L’OCDE évalue les compétences des adultes

OpenAIRE

Bardi, Anne-Marie

2014-01-01

Une dizaine d’années après les premiers résultats du Programme international de suivi des acquis des élèves (PISA), l’Organisation de coopération et de développement économiques (OCDE) livre une étude sur les compétences des adultes de 16 à 65 ans. Ce nouveau Programme pour l’évaluation internationale des compétences des adultes (PIIAC) est conçu en cycles, dont le premier s’achève en 2013. Il vise à informer sur la maîtrise des compétences jugées indispensables pour évoluer dans un monde hyp...

COMP-1 promotes competitive advantage of nematode sperm

Science.gov (United States)

Hansen, Jody M; Chavez, Daniela R; Stanfield, Gillian M

2015-01-01

Competition among sperm to fertilize oocytes is a ubiquitous feature of sexual reproduction as well as a profoundly important aspect of sexual selection. However, little is known about the cellular mechanisms sperm use to gain competitive advantage or how these mechanisms are regulated genetically. In this study, we utilize a forward genetic screen in Caenorhabditis elegans to identify a gene, comp-1, whose function is specifically required in competitive contexts. We show that comp-1 functions in sperm to modulate their migration through and localization within the reproductive tract, thereby promoting their access to oocytes. Contrary to previously described models, comp-1 mutant sperm show no defects in size or velocity, thereby defining a novel pathway for preferential usage. Our results indicate not only that sperm functional traits can influence the outcome of sperm competition, but also that these traits can be modulated in a context-dependent manner depending on the presence of competing sperm. DOI: http://dx.doi.org/10.7554/eLife.05423.001 PMID:25789512

Tennessee Comptroller of the Treasury (TN COMP)

Data.gov (United States)

Social Security Administration — The Tennessee Comptroller of the Treasury (TN COMP) uses SSA's assistance in administering the Tennessee Property Tax Rebate Program. SSA provides assistance through...

The CompHP Core Competencies Framework for Health Promotion in Europe

Science.gov (United States)

Barry, Margaret M.; Battel-Kirk, Barbara; Dempsey, Colette

2012-01-01

Background: The CompHP Project on Developing Competencies and Professional Standards for Health Promotion in Europe was developed in response to the need for new and changing health promotion competencies to address health challenges. This article presents the process of developing the CompHP Core Competencies Framework for Health Promotion across…

Apprentissage mobile et acquisition de la compétence pluriculturelle

Directory of Open Access Journals (Sweden)

LI Yue

2016-11-01

Full Text Available À mesure de l’évolution accélérée des technologies modernes, de nouveaux moyens d’apprentissage sont apparus dans le domaine de l’éducation, ce qui nous amène à nous demander comment en profiter en vue de favoriser l’enseignement/apprentissage du FLE. Dans cet article, nous prêtons une attention particulière à l’application de l’apprentissage mobile dans l’acquisition de la compétence pluriculturelle. Après une analyse de la compétence pluriculturelle, de l’apprentissage mobile, et de sa potentialité de développement en Chine, nous présentons les applications potentielles de l’apprentissage mobile dans l’acquisition de la compétence pluriculturelle des apprenants chinois de français.

CompTIA A+ complete study guide exams 220-801 and 220-802

CERN Document Server

Docter, Quentin; Skandier, Toby

2012-01-01

CompTIA Authorized, fully updated Study Guide for the leading IT certification: CompTIA A+ CompTIA A+ is the de facto certification for IT technicians. Some vendors even require employees to achieve certification as part of their job training. This book prepares you for both required exams: 220-801 and 220-802. Totally updated to cover the 2012 exams, this popular prep guide covers all the exam objectives. Readers will also have access to additional study tools, including the Sybex Test Engine with bonus practice exams, electronic flashcards, and a glossary of important terms in searchable PD

Autosomal dominant precocious osteoarthropathy due to a mutation of the cartilage oligomeric matrix protein (COMP) gene: further expansion of the phenotypic variations of COMP defects

Energy Technology Data Exchange (ETDEWEB)

Kawaji, Hiroyuki [Department of Orthopaedic Surgery, Sanyudo Hospital, 6-1-219 Chuou, Yonezawa, Yamagata 992-0045 (Japan); Nishimura, Gen [Department of Radiology, Nasu Chuou Hospital, Tochigi (Japan); Watanabe, Sobei; Sasaki, Akira; Sano, Tokuhisa [Department of Orthopaedic Surgery, Tohoku Kohsei-Nenkin Hospital, Miyagi (Japan); Mabuchi, Akihiko; Ikeda, Toshiyuki; Ikegawa, Shiro [Laboratory for Bone and Joint Diseases, SNP Research Center, Tokyo (Japan); Ohashi, Hirofumi [Division of Medical Genetics, Saitama Children' s Medical Center, Saitama (Japan)

2002-12-01

We report on a Japanese family of four generations with an autosomal dominant precocious osteoarthropathy. The cardinal clinical manifestations of affected individuals were painful weight-bearing large joints, which started in late childhood or adolescence. The radiological hallmarks included coxa plana, mild epiphyseal dysplasia of the knee, and round talar domes with tibiotalar slant in childhood, which evolved into degenerative joint diseases in adulthood. The disease phenotype was cosegregated with a mutation of the cartilage oligomeric matrix protein (COMP) gene in the family members, who underwent molecular evaluation. COMP mutations have been reported in a mild form of multiple epiphyseal dysplasia (MED), Ribbing type, as well as allied disorders with more severe manifestations, such as MED Fairbank type and pseudoachondroplasia. Unlike previously reported cases with the Ribbing type, the present patients did not have short stature or brachydactyly. This report expands further the phenotypic variations of COMP defects. (orig.)

Compétences pour les PME de l'Amérique centrale dans l'économie ...

International Development Research Centre (IDRC) Digital Library (Canada)

... compétences nécessaires; b) des recherches pour comprendre les modèles sociaux ... Il existe un lien bien documenté entre les compétences nécessaires pour ... Bien que ces compétences ne soient pas nécessairement axées sur les TIC, ...

Les compétences évaluatives des formateurs d'enseignants

OpenAIRE

Jorro , Anne

2005-01-01

Dans cette communication, je présenterai une recherche exploratoire conduite auprès de formateurs d'enseignants dont les missions d'accompagnement des professeurs - stagiaires supposent des compétences évaluatives. Or, les formateurs d'enseignants entrevoient quasi naturellement la nécessité de gagner des compétences analytiques sur l'activité observée. Ces professionnels recourent plus volontiers à des moments d'analyse de pratiques et déclarent éprouver des difficultés à investir l'évaluati...

CompTIA Security+ Review Guide Exam SY0-301

CERN Document Server

Stewart, James M

2011-01-01

Reinforce your preparation for CompTIA's new Security+ exam with this focused review tool Before you take CompTIA's new Security+ exam SY0-301, reinforce your learning with a thorough review and lots of practice. The new edition of this concise guide helps you do just that. It covers all six domains of exam SY0-301, all exam objectives, and includes a helpful "Exam Essentials" section after each domain to help you zero in on what you need to know for the exam. A companion CD offers additional study tools, including two complete practice exams, over a hundred electronic flashcards, and more.Rev

Mass-Spectrometry Based Structure Identification of "Known-Unknowns" Using the EPA's CompTox Dashboard (ACS Spring National Meeting) 4 of 7

Science.gov (United States)

The CompTox Dashboard is a publicly accessible database provided by the National Center for Computational Toxicology at the US-EPA. The dashboard provides access to a database containing ~720,000 chemicals and integrates a number of our public-facing projects (e.g. ToxCast and Ex...

A new Brief computerized cognitive screening battery (CompCogs for early diagnosis of Alzheimer's disease

Directory of Open Access Journals (Sweden)

Helenice Charchat Fichman

Full Text Available Abstract Screening tests for early diagnosis of dementia are of great clinical relevance. The ideal test set must be brief and reliable, and should probe cognitive components impaired in Alzheimer's disease (AD. Objectives: To develop a new Computerized Cognitive Screening test (CompCogs, and to investigate its validity for the early diagnosis of AD, and evaluate its heuristic value in understanding the processing of information in AD. Methods: The computerized neuropsychological performance battery, originally including six tests, was applied in forty seven patients with probable mild AD and 97 controls matched for age and education. This computerized neuropsychological test battery, developed with MEL Professional, allows control of timing and order of stimuli presentation, as well as recording of response type and latency. A brief-screening version, CompCogs, was selected using the most discriminative neuropsychological test variables derived from logistic regression analysis. Full battery administration lasted about 40 minutes, while the CompCogs took only 15 minutes. Results: CompCogs included the Face test (correct response and Word and Forms with Short term memory tests (reaction time. CompCogs presented 91.8% sensitivity and 93.6% specificity for the diagnosis of AD using ROC analyses of AD diagnosis probability derived by logistic regression. Conclusions: CompCogs showed high validity for AD early diagnosis and, therefore, may be a useful alternative screening instrument.

[Clinical features and COMP gene mutation in a family with a pseudoachondroplasia child].

Science.gov (United States)

Lu, Chun-Ting; Guo, Li; Zahng, Zhan-Hui; Lin, Wei-Xia; Song, Yuan-Zong; Feng, Lie

2013-11-01

This study aimed to report the clinical characteristics and COMP gene mutation of a family with pseudoachondroplasia (PSACH), a relatively rare spinal and epiphyseal dysplasia that is inherited as an autosomal dominant trait. Clinical information on a 5-year-2-month-old PSACH child and his parents was collected and analyzed. Diagnosis was confirmed by PCR amplification and direct sequencing of all the 19 exons and their flanking sequences of COMP gene, and the mutation was further ascertained by cloning analysis of exon 10. The child presented with short and stubby fingers, bow leg, short limb dwarfism and metaphysic broadening in long bone as well as lumbar lordosis. A mutation c.1048_1116del (p.Asn350_Asp372del) in exon 10, inherited from his father who did not demonstrate any phenotypic feature of PSACH, was detected in the child. PSACH was diagnosed definitively by means of COMP mutation analysis, on the basis of the child's clinical and imaging features. The non-penetrance phenomenon of COMP mutation was described for the first time in PSACH.

Cloud essentials CompTIA authorized courseware for exam CLO-001

CERN Document Server

Hausman, Kirk; Sampaio, Telmo

2013-01-01

CompTIA-Authorized courseware for the Cloud Essentials Exam (CLO-001) What better way to get up to speed on cloud computing than with this new book in the popular Sybex Essentials series? Cloud Essentials covers the basics of cloud computing and its place in the modern enterprise. Explore public and private clouds; contrast the ""as a service"" models for PaaS, SaaS, IaaS, or XaaS platforms; plan security; and more. In addition, the book covers the exam objectives for the both the CompTIA Cloud Essentials (Exam CLO-001) exam and the EXIN Cloud Computing Foundation (EX0-1

Immediate loading versus immediate provisionalization of maxillary single-tooth replacements: a prospective randomized study with BioComp implants

NARCIS (Netherlands)

Lindeboom, Jerome A.; Frenken, Joost W.; Dubois, Leander; Frank, Michael; Abbink, Ingmar; Kroon, Frans H.

2006-01-01

PURPOSE: The aim of this prospective randomized study was to evaluate the clinical outcome of immediately loaded solid plasma sprayed (TPS) BioComp (BioComp Industries BV, Vught, The Netherlands) implants versus immediate provisionalized but non-loaded BioComp implants in the anterior and premolar

Ingénierie des compétences et scénarisation pédagogique

Directory of Open Access Journals (Sweden)

Josianne Basque

2007-01-01

Full Text Available Cet article décrit un processus d’ingénierie éducative orienté compétences d’une activité d’autoévaluation et son intégration à un scénario pédagogique de cours à distance. Cette description est documentée par deux cas d’application dans un contexte de formation universitaire à distance. Le travail d’ingénierie utilise une approche en autogestion des compétences pour concevoir l’activité d’autoévaluation et l’instrumentaliser avec l’outil logiciel web d’autodiagnostic des compétences, appelé Compétences+. Cet acte d’ingénierie pédagogique porte l’attention de l’enseignant-concepteur sur une démarche centrée sur l’apprentissage dans une perspective d’autogestion des connaissances et de sa validation dans un usage en contexte isomorphe à une situation professionnelle réelle.

SlaVaComp Fonts Converter

Directory of Open Access Journals (Sweden)

Simon Skilevic

2013-12-01

Full Text Available This paper presents a fonts converter that was developed as a part of the Freiburg project on historical corpus linguistics. The tool named SlaVaComp-Konvertierer converts Church Slavonic texts digitized with non-Unicode fonts into the Unicode format without any loss of information contained in the original file and without damage to the original formatting. It is suitable for the conversion of all idiosyncratic fonts—not only Church Slavonic—and therefore can be used not only in Palaeoslavistic, but also in all historical and philological studies.

SyGuS-Comp 2016: Results and Analysis

Directory of Open Access Journals (Sweden)

Rajeev Alur

2016-11-01

Full Text Available Syntax-Guided Synthesis (SyGuS is the computational problem of finding an implementation f that meets both a semantic constraint given by a logical formula φ in a background theory T, and a syntactic constraint given by a grammar G, which specifies the allowed set of candidate implementations. Such a synthesis problem can be formally defined in SyGuS-IF, a language that is built on top of SMT-LIB. The Syntax-Guided Synthesis Competition (SyGuS-Comp is an effort to facilitate, bring together and accelerate research and development of efficient solvers for SyGuS by providing a platform for evaluating different synthesis techniques on a comprehensive set of benchmarks. In this year's competition we added a new track devoted to programming by examples. This track consisted of two categories, one using the theory of bit-vectors and one using the theory of strings. This paper presents and analyses the results of SyGuS-Comp'16.

Hydroxychloroquine induces inhibition of collagen type II and oligomeric matrix protein COMP expression in chondrocytes

Directory of Open Access Journals (Sweden)

Tao Li

2016-06-01

Full Text Available The aim of this study was to investigate the effect of hydroxychloroquine on the level of collagen type II and oligomeric matrix protein COMP expression in chondrocytes of knee osteoarthritis. The rate of growth in cartilage cells was analyzed using MTT assay whereas the Col-2 and COMP expression levels were detected by RT-PCR and Western blotting analyses. For the determination of MMP-13 expression, ELISA test was used. The results revealed no significant change in the rate of cartilage cell proliferation in hydroxychloroquine-treated compared to untreated cells. Hydroxychloro-quine treatment exhibited concentration- and time-dependent effect on the inhibition of collagen type II and COMP expression in chondrocytes. However, its treatment caused a significant enhancement in the expression levels of MMP-13 compared to the untreated cells. Therefore, hydroxychloro-quine promotes expression of MMP-13 and reduces collagen type II and COMP expression levels in chondrocytes without any significant change in the growth of cells.

Informatisation de la gestion des compétences : évaluation de la démarche dans une collectivité territoriale

OpenAIRE

Bachelet, Catherine; Galey, Béatrice

2013-01-01

Notion répandue mais difficile à cerner, la gestion des compétences peut être définie comme une instrumentation sur laquelle les acteurs professionnels de la GRH se fondent pour instruire leurs décisions de gestion (Gilbert, 2003). Constituée d'un « ensemble de pratiques visant à acquérir, stimuler et réguler les compétences des salariés » (Defélix et Retour, 2003), elle permet d'améliorer l'adéquation entre les compétences nécessaires et les compétences disponibles, pour optimiser la compéti...

Radar Precoder Design for Spectral Coexistence with Coordinated Multi-point (CoMP) System

OpenAIRE

Mahal, Jasmin A.; Khawar, Awais; Abdelhadi, Ahmed; Clancy, T. Charles

2015-01-01

This paper details the design of precoders for a MIMO radar spectrally coexistent with a MIMO cellular network. We focus on a coordinated multi-point (CoMP) system where a cluster of base stations (BSs) coordinate their transmissions to the intended user. The radar operates in two modes, interference-mitigation mode when it avoids interference with the CoMP system and cooperation mode when it exchanges information with it. Using either the conventional Switched Null Space Projection (SNSP) or...

COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice.

Directory of Open Access Journals (Sweden)

Joanna Kosacka

Full Text Available BACKGROUND: Leptin-deficient ob/ob mice are a model of type 2 diabetes induced peripheral neuropathy. Ob/ob mice exhibit obesity, insulin resistance, hyperglycaemia, and alterations of peripheral nerve fibres and endoneural microvessels. Here we test the hypothesis that cartilage oligomeric matrix protein (COMP-Ang-1, a soluble and stabile form of Ang-1 which promotes angiogenesis and nerve growth, improves regeneration of nerve fibres and endoneural microvessels in ob/ob mice. METHODS AND FINDINGS: COMP-Ang-1 (100 ng/ml or NaCl were intraperitoneally (i.p. injected into male (N = 184, 3-month old, ob/ob or ob/+ mice for 7 and 21 days. We measured expression of Nf68, GAP43, Cx32, Cx26, Cx43, and TNFα in sciatic nerves using Western blot analysis. To investigate the inflammation in sciatic nerves, numbers of macrophages and T-cells were counted after immunofluorescence staining. In ultrathin section, number of myelinated/non-mylinated nerve fibers, g-ratio, the thickness of Schwann cell basal lamina and microvessel endothelium were investigated. Endoneural microvessels were reconstructed with intracardial FITC injection. Treatment with COMP-Ang-1 over 21 days significantly reduced fasting blood glucose and plasma cholesterol concentrations compared to saline treated ob/ob mice. In addition, COMP-Ang-1 treatment: 1 up-regulated expression of Nf68 and GAP43; 2 improved expression of gap junction proteins including connexin 32 and 26; 3 suppressed the expression of TNFα and Cx43 and 4 led to decreased macrophage and T-cell infiltration in sciatic nerve of ob/ob mice. The significant changes of sciatic nerve ultrastructure were not observed after 21-day long COMP-Ang-1 treatment. COMP-Ang-1 treated ob/ob mice displayed regeneration of small-diameter endoneural microvessels. Effects of COMP-Ang-1 corresponded to increased phosphorylation of Akt and p38 MAPK upon Tie-2 receptor. CONCLUSIONS: COMP-Ang-1 recovers molecular biomarkers of neuropathy

Cartilage oligomeric matrix protein (COMP) in rheumatoid arthritis and its correlation with sonographic knee cartilage thickness and disease activity.

Science.gov (United States)

Sakthiswary, Rajalingham; Rajalingam, Shamala; Hussein, Heselynn; Sridharan, Radhika; Asrul, Abdul Wahab

2017-12-01

The aim of the study is to investigate the correlation of serum cartilage oligomeric matrix protein (COMP) levels with articular cartilage damage based on sonographic knee cartilage thickness (KCT) and disease activity in rheumatoid arthritis (RA). A total of 61 RA patients and 27 healthy controls were recruited in this study. Serum samples were obtained from all subjects to determine the serum COMP levels. All subjects had bilateral ultrasound scan of their knees. The KCT was based on the mean of measurements at three sites: the medial condyle, lateral condyle and intercondylar notch. Besides, the RA patients were assessed for their disease activity based on 28-joint-based Disease Activity Score (DAS 28). Serum COMP concentrations were significantly elevated in the RA patients compared to the controls (p = 0.001). The serum COMP levels had an inverse relationship with bilateral KCT in RA subjects and the healthy controls. COMP correlated significantly with disease activity based on DAS 28 (r = 0.299, p = 0.010), disease duration (r = 0.439, p = correlation between serum COMP and DAS 28 scores was comparable to the traditional markers of inflammation: erythrocyte sedimentation rate (ESR) (r = 0.372, p = 0.003) and C-reactive protein (CRP) (r = 0.305, p = 0.017). The serum COMP is a promising biomarker in RA which reflects disease activity and damage to the articular cartilage.

Modelagem de dispositivo Iosipescu para medição de propriedades de cisalhamento de materiais compósitos

OpenAIRE

Fabrício Nascimento Ribeiro

2013-01-01

Os projetos de novas aeronaves possuem suas estruturas primárias fabricados em materiais compósitos, o que resulta em diferentes tipos de cargas agindo em peças de compósitos. O comportamento de compósitos sujeitos a carga de cisalhamento é algo difícil de caracterizar especialmente porque os ensaios de cisalhamento possuem dificuldades em obter uma condição de cisalhamento puro e uniforme. O presente trabalho busca modelar o ensaio de cisalhamento Iosipescu com o método de elementos finitos,...

Développer des compétences interactionnelles en collaborant à distance

Directory of Open Access Journals (Sweden)

Charlotte Dejean-Thircuir

2010-01-01

Full Text Available Cet article vise à montrer de quelles façons des étudiants d’un Master2 professionnel de didactique des langues engagés dans la réalisation d’une tâche collaborative à distance sont amenés à mettre en œuvre et à développer des compétences interactionnelles et des compétences instrumentales en construisant des schèmes d’utilisation de l’outil de communication qu’est le chat, dans ce contexte particulier. Cette étude s’inscrit dans le champ de la communication pédagogique médiatisée par ordinateur; l’analyse des interactions verbales entre étudiants s’appuie sur des outils issus du champ de la pragmatique linguistique interactionniste.

Compósitos a partir de materiais de fontes renováveis como alternativa para o desenvolvimento de produtos

Directory of Open Access Journals (Sweden)

Eliana Paula Calegari

2016-04-01

Full Text Available A preocupação ambiental tem gerado interesse na pesquisa de novos materiais que estejam alinhados com os princípios da sustentabilidade. Entre esses materiais, atualmente, encontram-se os compósitos produzidos a partir de recursos de fontes renováveis. Este artigo apresenta os resultados de um estudo de caso acerca de produtos em que são empregados os referidos compósitos. Realizou-se uma pesquisa na rede mundial de computadores usando a ferramenta de buscas google sobre produtos fabricados com esses compósitos e comparou-se com produtos fabricados a partir de materiais usualmente utilizados na indústria, tais como polímeros, metais e cerâmicas. Constatou-se que os compósitos feitos a partir de fontes renováveis estão sendo, principalmente, aplicados em embalagens, na produção de ferramentas para jardinagem e vasos para plantas. Dessa forma, observou-se que os referidos compósitos podem substituir materiais comumente empregados na indústria atendendo aos requisitos funcionais e estéticos demandados na confecção desses produtos.

Compósitos de borracha natural com polianilina Composites of natural rubber with polyaniline

Directory of Open Access Journals (Sweden)

Patrini D. Galiani

2007-06-01

Full Text Available Compósitos de borracha natural (Hevea brasiliensis-BN/polianilina - PANI, com diferentes composições foram obtidos através da polimerização por emulsão do monômero anilina na presença da BN e do ácido dodecilbenzeno sulfônico (DBSA. Filmes finos e homogêneos foram obtidos por prensagem a quente. Os compósitos foram caracterizados por condutividade elétrica, FTIR, UV-vis-NIR, DSC e difração de raios X. Compósito com condutividade elétrica cerca de 14 ordens de grandeza maior que a BN foi obtido. Este alto valor de condutividade é atribuído à formação da PANI no estado dopado no compósito, que foi verificado através das técnicas de UV-vis-NIR e FTIR. Os resultados obtidos com a técnica de DSC e difratometria de raios X indicaram que os polímeros são imiscíveis e que a presença da borracha não altera significantemente a fase cristalina da PANI-DBSA no compósito.In this work composites with different compositions were obtained from natural rubber (Hevea brasiliensis (NR and polyaniline (PANI using the emulsion polymerization of aniline in the presence of NR and dodecylbenzenesulfonic acid (DBSA. The samples in film form were obtained by pressing the precipitate at 100 °C for 5 minutes. The composites were characterized by electrical conductivity, Fourier-transform infrared spectroscopy (FTIR, UV-vis-NIR spectroscopy, differential scanning calorimetry (DSC and X ray diffraction. Composites with electrical conductivity about 14 orders of magnitude higher than NR were obtained. The UV-vis-NIR and FTIR spectra showed that PANI-DBSA was formed in the composites, thus making it responsible for their high conductivity. The DSC thermograms indicated that the two polymers are immiscible and X ray diffraction evidenced that NB does not considerably affect PANI-DBSA crystalline phase in the composite.

The EPA CompTox Dashboard and Underpinning Software Architecture – a platform for data integration for environmental chemistry data (ACS Fall Meeting 7 of 12)

Science.gov (United States)

The CompTox Dashboard was developed by the Environmental Protection Agency’s National Center for Computational Toxicology. This dashboard has been architected in a manner that allows for the deployment of multiple “applications”, both as publicly available databases, and for dep...

Êtres capables et compétents : lecture anthropologique et pistes pragmatiques

OpenAIRE

Genard, Jean-Louis; Cantelli, Fabrizio

2008-01-01

Les termes « compétences » et « capacités » occupent depuis quelques années une place de plus en plus importante dans le vocabulaire de la sociologie, notamment de la sociologie pragmatique. On les retrouve toutefois aussi dans d’autres champs théoriques (le terme capabilities chez Amartya Sen) ou dans le vocabulaire des politiques publiques qui évoquent des politiques de « capacitation », ou des « seuils de compétences ». Face à ce constat, l’article développe l’hypothèse d’un véritable tour...

Functional Development of the Octenol Response in Aedes aegypti

Science.gov (United States)

2013-03-07

the expression of biogenic amine receptor genes in the antennae of honey bees (Apis mellifera). J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav...Masterman, R., Ross, R., and Mesce, K. A. (2003). Hygienic behavior in the honey bee (Apis mellifera L.) and the modulatory role of octopamine. J...CO2, octenol, lactic acid, and ammonia, is carried out by recep- tor proteins located in the dendritic membrane of ORNs; these receptors belong to

Comparative Analyses of Aryl Hydrocarbon Receptor Structure, Function, and Evolution in Marine Mammals

Science.gov (United States)

2007-02-01

function in early vertebrates: inducibility of cytochrome P450 1A in agnathan and elasmobranch fish . Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 120...J.Y., A.G. McArthur and J.J. Stegeman. 2005b. Characterization of a cetacean aromatase (CYP19) and the phylogeny and functional conservation of... phylogeny of cetaceans prompts revision of morphological transformations. Trends in Ecology and Evolution 10:328-334. Nei, M., P. Xu and G. Glazko

The semantics of Chemical Markup Language (CML for computational chemistry : CompChem

Directory of Open Access Journals (Sweden)

Phadungsukanan Weerapong

2012-08-01

Full Text Available Abstract This paper introduces a subdomain chemistry format for storing computational chemistry data called CompChem. It has been developed based on the design, concepts and methodologies of Chemical Markup Language (CML by adding computational chemistry semantics on top of the CML Schema. The format allows a wide range of ab initio quantum chemistry calculations of individual molecules to be stored. These calculations include, for example, single point energy calculation, molecular geometry optimization, and vibrational frequency analysis. The paper also describes the supporting infrastructure, such as processing software, dictionaries, validation tools and database repositories. In addition, some of the challenges and difficulties in developing common computational chemistry dictionaries are discussed. The uses of CompChem are illustrated by two practical applications.

On-line process analysis innovation: DiComp (tm) shunting dielectric sensor technology

Science.gov (United States)

Davis, Craig R.; Waldman, Frank A.

1993-01-01

The DiComp Shunting Dielectric Sensor (SDS) is a new patent-pending technology developed under the Small Business Innovation Research Program (SBIR) for NASA's Kennedy Space Center. The incorporation of a shunt electrode into a conventional fringing field dielectric sensor makes the SDS uniquely sensitive to changes in material dielectric properties in the KHz to MHz range which were previously detectable only at GHz measurement frequencies. The initial NASA application of the SDS for Nutrient Delivery Control has demonstrated SDS capabilities for thickness and concentration measurement of Hoagland nutrient solutions. The commercial introduction of DiComp SDS technology for concentration and percent solids measurements in dispersions, emulsions and solutions represents a new technology for process measurements for liquids in a variety of industries.

The semantics of Chemical Markup Language (CML) for computational chemistry : CompChem.

Science.gov (United States)

Phadungsukanan, Weerapong; Kraft, Markus; Townsend, Joe A; Murray-Rust, Peter

2012-08-07

: This paper introduces a subdomain chemistry format for storing computational chemistry data called CompChem. It has been developed based on the design, concepts and methodologies of Chemical Markup Language (CML) by adding computational chemistry semantics on top of the CML Schema. The format allows a wide range of ab initio quantum chemistry calculations of individual molecules to be stored. These calculations include, for example, single point energy calculation, molecular geometry optimization, and vibrational frequency analysis. The paper also describes the supporting infrastructure, such as processing software, dictionaries, validation tools and database repositories. In addition, some of the challenges and difficulties in developing common computational chemistry dictionaries are discussed. The uses of CompChem are illustrated by two practical applications.

Estudo do comportamento da resina base na formulação de compósitos de politetrafluoretileno com bronze

OpenAIRE

Ronaldo Euzébio Bento

2011-01-01

Resumo: Esse trabalho concentra os estudos na investigação das propriedades de resistência a tração e alongamento do compósito de Politetrafluoretileno (PTFE) com 60% de bronze após a substituição do tipo de PTFE utilizado na formulação desse compósito. Atualmente esse compósito utiliza PTFE convencional na formulação e o objetivo é alterar para PTFE modificado. A motivação para essa alteração deveu-se ao fato que o PTFE convencional apresenta disponibilidade limitada dificultando o desenvolv...

CompTIA Linux+ study guide exam LX0-103 and exam LX0-104

CERN Document Server

Bresnahan, Christine

2015-01-01

CompTIA Authorized Linux+ prepCompTIA Linux+ Study Guide is your comprehensive study guide for the Linux+ Powered by LPI certification exams. With complete coverage of 100% of the objectives on both exam LX0-103 and exam LX0-104, this study guide provides clear, concise information on all aspects of Linux administration, with a focus on the latest version of the exam. You'll gain the insight of examples drawn from real-world scenarios, with detailed guidance and authoritative coverage of key topics, including GNU and Unix commands, system operation, system administration, system services, secu

CompTIA Linux+ Complete Study Guide (Exams LX0-101 and LX0-102)

CERN Document Server

Smith, Roderick W

2010-01-01

Prepare for CompTIA's Linux+ Exams. As the Linux server and desktop markets continue to grow, so does the need for qualified Linux administrators. CompTIA's Linux+ certification (Exams LX0-101 and LX0-102) includes the very latest enhancements to the popular open source operating system. This detailed guide not only covers all key exam topics—such as using Linux command-line tools, understanding the boot process and scripts, managing files and file systems, managing system security, and much more—it also builds your practical Linux skills with real-world examples. Inside, you'll find:. Full co

Emprego experimental da placa de compósito poli-hidroxibutirado/hidroxiapatita na fixação femoral em gatos

Directory of Open Access Journals (Sweden)

E.G.L. Alves

2010-10-01

Full Text Available Avaliou-se o compósito de poli-hidroxibutirado (PHB 70% e hidroxiapatita (HA 30% na forma de placas para fixação óssea em gatos. Foram usadas placas do compósito com 60mm de comprimento por 10mm de largura e espessura variando de 3mm no centro a 5mm nas extremidades, com seis orifícios. A placa do compósito foi empregada na fixação de osteotomia de fêmur em quatro gatos, totalizando seis intervenções. Verificou-se a ruptura de cinco placas (83,3% até o quarto dia e de uma placa (16,7% aos 21 dias, quando se observou um calo ósseo exuberante. O resultado da implantação da placa no gato mostrou que o compósito não possui resistência suficiente para ser empregado como placas de fixação de fêmur em gatos.

Teaching Competencies for the Online Environment | Enseigner les compétences pour l’environnement en ligne

Directory of Open Access Journals (Sweden)

Heather Marie Farmer

2016-08-01

Full Text Available The goals of this study are to identify key competency areas that lead to success in online instruction and to develop a framework that supports professional development and self-assessment. To identify the key competency areas, skills and behaviours presented within current literature were analyzed. Secondly, gaps were identified and levels of competence were determined within each key competency area. The resulting analysis produced the Online Teaching Competency (OTC Matrix including five competency areas: Community & Netiquette, Active Teaching/Facilitating, Instructional Design, Tools & Technology, and Leadership & Instruction. This leveled competency matrix can be used to inform professional development in the online teaching environment and is also a useful guide in the areas of self-assessment, portfolio design, and the development and evaluation of professional development opportunities. Cette étude a comme objectifs de cerner les principaux domaines de compétences qui mènent à la réussite de l’instruction en ligne et de développer un cadre qui soutient le développement professionnel et l’autoévaluation. Afin de cerner les principaux domaines de compétences, une analyse des aptitudes et comportements présentés dans les études actuelles a été réalisée. Deuxièmement, les écueils ont été cernés et les niveaux de compétence ont été déterminés au sein de chaque domaine de compétences. L’analyse qui en a résulté a généré la matrice des compétences de l’enseignement en ligne, comprenant cinq domaines de compétences : collectivité et nétiquette, enseignement actif/animation active, conception de l’instruction, outils et technologie, ainsi que leadership et instruction. Cette matrice graduée peut servir à façonner le développement professionnel dans un environnement d’enseignement en ligne. Elle sert aussi de guide pratique pour les domaines de l’auto-évaluation, de la conception de

Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases.

Directory of Open Access Journals (Sweden)

Katarzyna A Piróg

Full Text Available Pseudoachondroplasia (PSACH and multiple epiphyseal dysplasia (MED are skeletal disorders resulting from mutations in COMP, matrilin-3 or collagen IX and are characterised by short-limbed dwarfism and premature osteoarthritis. Interestingly, recent reports suggest patients can also manifest with muscle weakness. Here we present a detailed analysis of two mouse models of the PSACH/MED disease spectrum; ΔD469 T3-COMP (PSACH and V194D matrilin-3 (MED. In grip test experiments T3-COMP mice were weaker than wild-type littermates, whereas V194D mice behaved as controls, confirming that short-limbed dwarfism alone does not contribute to PSACH/MED-related muscle weakness. Muscles from T3-COMP mice showed an increase in centronuclear fibers at the myotendinous junction. T3-COMP tendons became more lax in cyclic testing and showed thicker collagen fibers when compared with wild-type tissue; matrilin-3 mutant tissues were indistinguishable from controls. This comprehensive study of the myopathy associated with PSACH/MED mutations enables a better understanding of the disease progression, confirms that it is genotype specific and that the limb weakness originates from muscle and tendon pathology rather than short-limbed dwarfism itself. Since some patients are primarily diagnosed with neuromuscular symptoms, this study will facilitate better awareness of the differential diagnoses that might be associated with the PSACH/MED spectrum and subsequent care of PSACH/MED patients.

Acetylcholinesterase of the Sand Fly, Phlebotomus papatasi (Scopoli): Construction, Expression and Biochemical Properties of the G119S Orthologous Mutant

Science.gov (United States)

2014-12-10

C, Pasteur N, Philips A, Fort P, Raymond M: Insecticide resistance in mosquito vectors. Nature 2003, 423:136–137. 27. Weill W, Lutfalla G, Mogensen K...Chandre F, Berthomieu A, Berticat C, Pasteur N, Philips A, Fort P, Raymond M: Corrigendum:Insecticide resistance in mosquito vectors. Nature 2003...1 biochemical properties. Comp Biochem Physiol B 2008, 150:271–277. 46. Alout H, Labbé P, Berthomieu A, Pasteur N, Weill M: Multiple duplications of

COMP-angiopoietin 1 increases proliferation, differentiation, and migration of stem-like cells through Tie-2-mediated activation of p38 MAPK and PI3K/Akt signal transduction pathways

Energy Technology Data Exchange (ETDEWEB)

Kook, Sung-Ho [Cluster for Craniofacial Development and Regeneration Research, Institute of Oral Biosciences and School of Dentistry, Chonbuk National University, Jeonju (Korea, Republic of); Lim, Shin-Saeng [School of Dentistry and Dental Research Institute, Seoul National University, Seoul (Korea, Republic of); Cho, Eui-Sic; Lee, Young-Hoon; Han, Seong-Kyu; Lee, Kyung-Yeol [Cluster for Craniofacial Development and Regeneration Research, Institute of Oral Biosciences and School of Dentistry, Chonbuk National University, Jeonju (Korea, Republic of); Kwon, Jungkee [College of Veterinary Medicine, Chonbuk National University, Jeonju (Korea, Republic of); Hwang, Jae-Won; Bae, Cheol-Hyeon [Cluster for Craniofacial Development and Regeneration Research, Institute of Oral Biosciences and School of Dentistry, Chonbuk National University, Jeonju (Korea, Republic of); Seo, Young-Kwon [Research Institute of Biotechnology, Dongguk University, Seoul (Korea, Republic of); Lee, Jeong-Chae, E-mail: leejc88@jbnu.ac.kr [Cluster for Craniofacial Development and Regeneration Research, Institute of Oral Biosciences and School of Dentistry, Chonbuk National University, Jeonju (Korea, Republic of)

2014-12-12

Highlights: • COMP-Ang1 induces Tie-2 activation in BMMSCs, but not in primary osteoblasts. • Tie-2 knockdown inhibits COMP-Ang1-stimulated proliferation and osteoblastogenesis. • Tie-2 knockdown prevents COMP-Ang1-induced activation of PI3K/Akt and p38 MAPK. • COMP-Ang1 induces migration of cells via activation of PI3K/Akt and CXCR4 pathways. • COMP-Ang1 stimulates in vivo migration of PDLSCs into a calvarial defect site of rats. - Abstract: Recombinant COMP-Ang1, a chimera of angiopoietin-1 (Ang1) and a short coiled-coil domain of cartilage oligomeric matrix protein (COMP), is under consideration as a therapeutic agent capable of inducing the homing of cells with increased angiogenesis. However, the potentials of COMP-Ang1 to stimulate migration of mesenchymal stem cells (MSCs) and the associated mechanisms are not completely understood. We examined the potential of COMP-Ang1 on bone marrow (BM)-MSCs, human periodontal ligament stem cells (PDLSCs), and calvarial osteoblasts. COMP-Ang1 augmented Tie-2 induction at protein and mRNA levels and increased proliferation and expression of runt-related transcription factor 2 (Runx2), osterix, and CXCR4 in BMMSCs, but not in osteoblasts. The COMP-Ang1-mediated increases were inhibited by Tie-2 knockdown and by treating inhibitors of phosphoinositide 3-kinase (PI3K), LY294002, or p38 mitogen-activated protein kinase (MAPK), SB203580. Phosphorylation of p38 MAPK and Akt was prevented by siRNA-mediated silencing of Tie-2. COMP-Ang1 also induced in vitro migration of BMMSCs and PDLSCs. The induced migration was suppressed by Tie-2 knockdown and by CXCR4-specific peptide antagonist or LY294002, but not by SB203580. Furthermore, COMP-Ang1 stimulated the migration of PDLSCs into calvarial defect site of rats. Collectively, our results demonstrate that COMP-Ang1-stimulated proliferation, differentiation, and migration of progenitor cells may involve the Tie-2-mediated activation of p38 MAPK and PI3K/Akt pathways.

COMP-angiopoietin 1 increases proliferation, differentiation, and migration of stem-like cells through Tie-2-mediated activation of p38 MAPK and PI3K/Akt signal transduction pathways

International Nuclear Information System (INIS)

Kook, Sung-Ho; Lim, Shin-Saeng; Cho, Eui-Sic; Lee, Young-Hoon; Han, Seong-Kyu; Lee, Kyung-Yeol; Kwon, Jungkee; Hwang, Jae-Won; Bae, Cheol-Hyeon; Seo, Young-Kwon; Lee, Jeong-Chae

2014-01-01

Highlights: • COMP-Ang1 induces Tie-2 activation in BMMSCs, but not in primary osteoblasts. • Tie-2 knockdown inhibits COMP-Ang1-stimulated proliferation and osteoblastogenesis. • Tie-2 knockdown prevents COMP-Ang1-induced activation of PI3K/Akt and p38 MAPK. • COMP-Ang1 induces migration of cells via activation of PI3K/Akt and CXCR4 pathways. • COMP-Ang1 stimulates in vivo migration of PDLSCs into a calvarial defect site of rats. - Abstract: Recombinant COMP-Ang1, a chimera of angiopoietin-1 (Ang1) and a short coiled-coil domain of cartilage oligomeric matrix protein (COMP), is under consideration as a therapeutic agent capable of inducing the homing of cells with increased angiogenesis. However, the potentials of COMP-Ang1 to stimulate migration of mesenchymal stem cells (MSCs) and the associated mechanisms are not completely understood. We examined the potential of COMP-Ang1 on bone marrow (BM)-MSCs, human periodontal ligament stem cells (PDLSCs), and calvarial osteoblasts. COMP-Ang1 augmented Tie-2 induction at protein and mRNA levels and increased proliferation and expression of runt-related transcription factor 2 (Runx2), osterix, and CXCR4 in BMMSCs, but not in osteoblasts. The COMP-Ang1-mediated increases were inhibited by Tie-2 knockdown and by treating inhibitors of phosphoinositide 3-kinase (PI3K), LY294002, or p38 mitogen-activated protein kinase (MAPK), SB203580. Phosphorylation of p38 MAPK and Akt was prevented by siRNA-mediated silencing of Tie-2. COMP-Ang1 also induced in vitro migration of BMMSCs and PDLSCs. The induced migration was suppressed by Tie-2 knockdown and by CXCR4-specific peptide antagonist or LY294002, but not by SB203580. Furthermore, COMP-Ang1 stimulated the migration of PDLSCs into calvarial defect site of rats. Collectively, our results demonstrate that COMP-Ang1-stimulated proliferation, differentiation, and migration of progenitor cells may involve the Tie-2-mediated activation of p38 MAPK and PI3K/Akt pathways

Resistência de união de compósitos do tipo Bulk Fill: análise in vitro

Directory of Open Access Journals (Sweden)

Caroline de Farias CHARAMBA

2017-03-01

Full Text Available Resumo Introdução A classe dos compósitos Bulk-Fill tem obtido popularidade com a promessa de ser fotopolimerizado efetivamente em camadas de até quatro milímetros, fato que contrasta com os dois milímetros requisitados para os compósitos convencionais para manutenção da adesividade da restauração. Objetivo O objetivo deste estudo foi analisar a resistência de união à dentina de restaurações confeccionadas com compósitos do tipo Bulk-Fill. Material e método Foram utilizados 15 terceiros molares humanos, cuja superfície oclusal foi cortada e a dentina foi exposta. Esses elementos dentários foram divididos em três grupos conforme o material restaurador utilizado. O sistema adesivo usado foi o mesmo para todos os grupos. Posteriormente, os dentes restaurados foram cortados para originar palitos de aproximadamente 1 mm de largura, 1 mm de profundidade e 8 mm de altura, que foram fixados às garras do dispositivo de microtração. Foram utilizados dez palitos de cada dente, totalizando 50 palitos por grupo. Os dados de resistência de união à microtração foram expressos em megapascal (MPa. As fraturas foram analisadas em microscópio óptico. Os dados foram analisados através dos testes ANOVA e Tukey (p<0,05. Resultado Os três compósitos estudados diferiram estatisticamente entre si (p<0,000. Os compósitos Bulk-Fill apresentaram resistências de união semelhantes e superiores ao convencional (p<0,000. A fratura mais encontrada foi a mista, em todos os grupos. Conclusão Os compósitos Bulk-Fill apresentaram maiores valores de resistência de união com a técnica restauradora utilizada.

Modelos de percolação elétrica aplicados para compósitos poliméricos condutores

Directory of Open Access Journals (Sweden)

Paulo Henrique da Silva Leite Coelho

Full Text Available Resumo O presente artigo apresenta a aplicação e adequação dos modelos de percolação elétrica em trabalhos experimentais e teóricos da literatura para compósitos poliméricos condutores. Foi realizado um levantamento das publicações referentes aos modelos estudados para os diferentes tipos de cargas condutoras mais aplicadas na preparação destes compósitos, tais como pós metálicos, grafite, negro de fumo, nanofibras e nanotubos de carbono. A discussão está apresentada quanto à adequação dos modelos ao comportamento dos compósitos na influência das cargas nas propriedades elétricas de matrizes poliméricas.

Equivalent flow rate concept used in near field transport model COMP23 - Proposed values for SR 97

International Nuclear Information System (INIS)

Moreno, L.

1998-11-01

SKB is using NUCTRAN to calculate transport of radionuclides from a possible defective canister into the far field. NUCTRAN is included in the Performance Assessment model chain that calculates the release from the canister into the biosphere. In the chain, NUCTRAN is denoted COMP23. In order to calculate the transport of radionuclides by diffusion into the flowing water in the rock, NUCTRAN uses the concept of equivalent flow rate, Q eq . To calculate the value of Q eq in the different paths, COMP23 needs information about the Darcy velocity, the geometry of the system, material properties and the flow porosity in the rock. At present, this information is supplied to COMP23 by means of three parameters. The aim of this note is to propose a method to calculate the flow equivalent within the SR 97 project. Estimated intervals of the factors to adopt HYDRASTAR results to COMP23 are presented. Since it is difficult to give general validity to the factors, solely proposed factor intervals are presented to obtain equivalent flow rate values for COMP23. To obtain accurate equivalent flow rate values, information about the hydraulic conditions at canister locations in the groundwater model should be available for the near field model or the Q eq values could be calculated directly in the groundwater flow model. One of the main tasks in the SR 97 project is to show the barrier performance of the rock using different alternative models for flow and transport. In addition, the Alternative Model Project (AMP) aims to show how robust the assessment model description is, in terms of relevant far field performance measures. In the AMP, three main approaches were used, namely, the Stochastic Continuum approach, the Channel Network model and the Discrete Feature Network model

Efeito do tratamento alcalino de fibras de Curauá sobre as propriedades de compósitos de matriz biodegradável

Directory of Open Access Journals (Sweden)

Lílian Vanessa Rossa Beltrami

2014-06-01

Full Text Available Neste trabalho avaliou-se a influência do tratamento alcalino das fibras de curauá, nas concentrações de 1, 5 e 10%(m/v de NaOH, nas propriedades dos compósitos com matriz de PHBV e 20% m/m de fibras de curauá. Os compósitos foram moldados por extrusão e injeção e avaliadas suas as propriedades morfológicas, térmicas e mecânicas. Os resultados de FTIR mostraram que o tratamento alcalino promoveu modificações na estrutura das fibras de curauá, comprovadas pela remoção da hemicelulose e da lignina, evidenciadas pela ausência das bandas típicas destes compostos. Nos compósitos com fibras de curauá tratadas com solução de NaOH na concentração de 5% apresentaram um aumento de 30% na resistência à flexão e 12% na resistência ao impacto, quando comparados aos compósitos com fibras sem tratamento. Estes resultados indicam que o tratamento alcalino promoveu uma melhoria na adesão das fibras na matriz, o que melhorou significativamente as propriedades mecânicas dos compósitos.

Jet-Like Flow and Thrust From a Flexible Flapping Foil in Stationary Fluid

Science.gov (United States)

2009-12-29

considered as a movable hinge point which travels over the flap region resulting in differential flap portions, pulling and pushing the fluid about this 15...Fliegenflugel und Hypothesen uber zugeordnete instationare Stromungseffekte,” J. Comp. Physiol., vol. 133, pp. 351–355, 1979. [24] Rayner, J. M. V., “A vortex...ring by giving an impulse to a circular disk and then dissolving it away,” J. App. Phys., vol. 24, no. 1, pp. 104, 1953. 17 [28] Wagner H., “ Uber die

Neurophysiological Study of Vector Responses to Repellents.

Science.gov (United States)

1980-08-01

hexanoic acid by the migratory locust and the honey bee . J. Comp. Physiol. 87, 277-284 (1973). Mctver, S. B.: Fine structure of antennal grooved pegs of the...and replace those receptor proteins undergoing normal or accelerated turnover. Half-times of 10 to 30 hr are associated with these processes. In the... Substitution for the a-hydroxyl of lactic acid by -SH, -Br, -NH2, =0, -CU13, or -H produced responses of varying degrees of effectiveness from strong (-SH, =0

Desenvolvimento e análise de compósitos cimentícios híbridos de alto desempenho

Directory of Open Access Journals (Sweden)

V. J. Ferrari

Full Text Available Neste trabalho, estudou-se o efeito da hibridização em compósitos cimentícios numa tentativa de modificar o material em sua microestrutura e melhorar o processo de transferência de tensões da matriz cimentícia para as fibras de aço. Para tanto, fibras curtas e microfibras de aço foram adicionadas a uma matriz cimentícia de argamassa para confecção de corpos-de-prova prismáticos entalhados e com dimensões de 150 mm x 150 mm x 500 mm. Os corpos-de-prova foram submetidos a ensaios de flexão com carga no meio do vão sob o controle dos deslocamentos de abertura da entrada do entalhe (CMOD. O desempenho dos compósitos híbridos foi comparado ao dos compósitos produzidos somente com a adição da fibra curta de aço e também ao da matriz sem fibras. Os resultados foram analisados considerando-se os parâmetros de tenacidade flexional e tenacidade ao fraturamento do material. O processo de hibridização permitiu obter compósitos de alto desempenho.

Compósitos à base de gesso com resíduos de EVA e vermiculita

OpenAIRE

Oliveira,Marilia P. de; Barbosa,Normando P.; Torres,Sandro M.; Leal,Antonio F.; Silva,Cibelle G.

2012-01-01

O gesso é um dos materiais de construção mais antigos de que se tem conhecimento. Algumas de suas propriedades lhes conferem vantagens, tais como resistência ao fogo e isolamentos térmico e acústico. Objetivou-se, com este trabalho, avaliar as propriedades físico-mecânicas de compósitos à base de gesso com a incorporação de resíduos da indústria de calçados, o etileno acetato de vinila (EVA) e a vermiculita. O desenvolvimento desses compósitos tem como propósito a produção de elementos de rev...

Entre structure et action : la compétence communicative des TIC

Directory of Open Access Journals (Sweden)

Serge Agostinelli

2011-06-01

Full Text Available Cet article théorique explore comment les concepts de structure et d’action permettent une approche originale du concept de compétence dans le domaine des TIC. Cette approche relève d’une recherche de compatibilité entre des modèles issus des Technologies qui proposent les structures socio-techniques et ceux des Sciences Humaines qui organisent l’action des individus. Les modèles théoriques invoqués de domaines disciplinaires différents (sociologie, ethnométhodologie, psychologie sociale, linguistique, sciences de l’éducation et sciences de l’information-communication donnent au concept de compétence en TIC une nouvelle consistance, plus anthropocentrée et moins technico-pratique. Ils posent la question du rapport entre micro et macro, du rapport de l’individu au groupe, et posent aussi la question ontologique des structures. Les compétences ne se réduisent pas à la seule connaissance des aspects techniques, mais sont élargies à la maîtrise des conditions d’utilisation adéquate et des possibilités offertes par la technique. Utiliser les technologies, c’est construire de la relation grâce aux compétences communicatives des TIC.This theoretical article investigates how the concepts of structure and action allow an original approach of the concept of skill in the field of ICT. This approach concerns a search for compatibility between stemming models Technologies which propose the socio-technical structures and those of the Human Sciences who organize the action of the individuals. The theoretical models called by different disciplinary domains (sociology, ethnomethodology, social psychology, linguistic, education, communication and information science give to the concept of skill in ICT a new consistency, more anthropology centred and less technico-practical. They ask the question of the relationship between micro and macro, the relationship of the individual to the group, and also ask the ontological question

Nig. J. Physiol. Sci.

African Journals Online (AJOL)

olayemitoyin

lasunigeria.org. Manuscript Accepted: May, 2011. INTRODUCTION. Nitric oxide synthase (NOS) is regulated by protein- protein interactions. Recently, we used real time measurement of basal NOS function by DAF assay in live endothelial cells ...

La transmission efficace des compétences via Internet : exemple pratique

NARCIS (Netherlands)

Caniëls, M.C.J.

2005-01-01

Les universités sont de plus en plus nombreuses à adopter des modèles pédagogiques novateurs, plutôt axés sur le développement des compétences que sur la reproduction des connaissances. Ces nouveaux modèles pédagogiques soulignent l’importance de la mise en application des connaissances et du

CompTIA A+ certification all-in-one for dummies

CERN Document Server

Clarke, Glen E

2012-01-01

Comprehensive coverage of everything you must know to pass CompTIA's A+ exam A+ is the gateway certification into many IT careers, and interest in certification is exploding. This bestselling A+ certification guide is updated to cover the new A+ exam. It includes the new Windows coverage and reflects the revised emphasis on objectives. Nine minibooks focus individually on specific hardware and OS characteristics including installation and configuration, diagnostics, preventive maintenance, motherboard and processors, printers, networking, and fundamentals. A companion website contains the popu

CompTIA network+ study guide exam N10-006

CERN Document Server

Lammle, Todd

2015-01-01

All-star N10-006 prep, fully updated for the new exam The CompTIA Network+ Study Guide is your one-stop comprehensive resource in preparing for exam N10-006 Bestselling author and networking Guru Todd Lammle guides you through 100% of all exam objectives detailing the fundamental concepts you will need to know to prepare for the exam. Coverage includes network technologies, installation and configuration, media and topologies, security, and much more, plus practical examples drawn from real-world situations. You also gain access to practice exams and electronic flashcards that facilitate info

Intelligence économique, compétitivité et cohésion sociale

Directory of Open Access Journals (Sweden)

Luc Marie Quoniam

2005-12-01

Full Text Available Book review: Intelligence économique, compétitivité et cohésion sociale by Bernard Carayon (.pdf rapportPublished by: Ministère de l’Intérieur français Année d'édition : 2003 Réf. : 9782110054913, 176 pages, 21x29,7 cm ISBN : 2-11-005491-3

Análise da influência do traço nas propriedades do compósito cimento-madeira

Directory of Open Access Journals (Sweden)

Alessandra Monique Weber

2017-08-01

Full Text Available Os compósitos de cimento com adição de madeira apresentam vantagens, quando comparados a outros materiais convencionais da construção civil, como resistência à água, ao fogo e aos agentes deterioradores. Um dos obstáculos para o uso desse compósito é a inibição causada pela madeira na cura do cimento, devido aos componentes da madeira afetarem as reações, tendo como consequência um compósito de baixa qualidade. Dessa forma, este trabalho teve por objetivo avaliar diferentes traços do compósito cimento-madeira, utilizando resíduos de Pinus spp., por meio de ensaios de laboratório. Foi utilizado o cimento Portland CP II Z 32, relação água/cimento igual a 0,4; o aditivo químico escolhido foi o cloreto de cálcio para acelerar a pega. Para a comparação de desempenho, foram delimitadas quatro dosagens diferentes, com teores de adição de madeira de 10%, 20%, 25% e 33% em relação à massa de cimento. Para a análise, foram feitos ensaios das propriedades físicas e mecânicas para todas as dosagens, sendo, posteriormente, submetidas à análise da variância e teste de Tukey. Os resultados dos ensaios das propriedades físicas e mecânicas dos compósitos demonstraram que, para as relações escolhidas, quanto menor for a adição de madeira melhores serão os resultados das propriedades, mas mesmo os traços com maiores teores de madeira apresentam resultados relevantes, atentando-se apenas para o fato da relação água/cimento ser baixa para os casos analisados, e, devido a isso, ter influenciado negativamente nos resultados.

Developing Consensus on the CompHP Professional Standards for Health Promotion in Europe

Science.gov (United States)

Speller, Viv; Parish, Richard; Davison, Heather; Zilnyk, Anna

2012-01-01

Building on the CompHP Core Competencies for health promotion the Professional Standards for Health Promotion have been developed and consulted on across Europe. The standards were formulated to fit within the complexity of professional, occupational and educational standards frameworks in Europe as learning outcome standards with performance…

CompTIA Network+ Review Guide (Exam N10-004)

CERN Document Server

Ferguson, Bill

2009-01-01

Serving as a concise, focused study aid to help you prepare for the leading non-vendor-specific networking certification exam, this book features more review questions and study review features than any other guide, with over 120 review questions, two bonus exams, and electronic Flashcard, as well as a searchable Glossary of Terms database on CD-ROM. Fully updated for the first revision of the CompTIA Network+ exam since 2005, the book is organized by exam objectives and broken into six parts corresponding to the six domain areas of the Network+ exam: technologies, media and topologies, device

Functional analysis of the interdependence between DNA uptake sequence and its cognate ComP receptor during natural transformation in Neisseria species.

Directory of Open Access Journals (Sweden)

Jamie-Lee Berry

Full Text Available Natural transformation is the widespread biological process by which "competent" bacteria take up free DNA, incorporate it into their genomes, and become genetically altered or "transformed". To curb often deleterious transformation by foreign DNA, several competent species preferentially take up their own DNA that contains specific DUS (DNA uptake sequence watermarks. Our recent finding that ComP is the long sought DUS receptor in Neisseria species paves the way for the functional analysis of the DUS-ComP interdependence which is reported here. By abolishing/modulating ComP levels in Neisseria meningitidis, we show that the enhancement of transformation seen in the presence of DUS is entirely dependent on ComP, which also controls transformation in the absence of DUS. While peripheral bases in the DUS were found to be less important, inner bases are essential since single base mutations led to dramatically impaired interaction with ComP and transformation. Strikingly, naturally occurring DUS variants in the genomes of human Neisseria commensals differing from DUS by only one or two bases were found to be similarly impaired for transformation of N. meningitidis. By showing that ComPsub from the N. subflava commensal specifically binds its cognate DUS variant and mediates DUS-enhanced transformation when expressed in a comP mutant of N. meningitidis, we confirm that a similar mechanism is used by all Neisseria species to promote transformation by their own, or closely related DNA. Together, these findings shed new light on the molecular events involved in the earliest step in natural transformation, and reveal an elegant mechanism for modulating horizontal gene transfer between competent species sharing the same niche.

Alors ? méthode de français fondée sur l'approche des compétences : niveau B1 : CD et DVD inclus

CERN Document Server

Di Giura, Marcella

2008-01-01

Une nouvelle méthode qui propose des stratégies spécifiques pour l'acquisition des compétences communicatives, linguistiques et culturelles. Alors ? respecte les échelles de compétences des niveaux A1, A2 et B1 du CECRL.

Phrenic motoneurons: output elements of a highly organized intraspinal network.

Science.gov (United States)

Ghali, Michael George Zaki

2018-03-01

pontomedullary respiratory network generates the respiratory pattern and relays it to bulbar and spinal respiratory motor outputs. The phrenic motor system controlling diaphragm contraction receives and processes descending commands to produce orderly, synchronous, and cycle-to-cycle-reproducible spatiotemporal firing. Multiple investigators have studied phrenic motoneurons (PhMNs) in an attempt to shed light on local mechanisms underlying phrenic pattern formation. I and colleagues (Marchenko V, Ghali MG, Rogers RF. Am J Physiol Regul Integr Comp Physiol 308: R916-R926, 2015.) recorded PhMNs in unanesthetized, decerebrate rats and related their activity to simultaneous phrenic nerve (PhN) activity by creating a time-frequency representation of PhMN-PhN power and coherence. On the basis of their temporal firing patterns and relationship to PhN activity, we categorized PhMNs into three classes, each of which emerges as a result of intrinsic biophysical and network properties and organizes the orderly contraction of diaphragm motor fibers. For example, early inspiratory diaphragmatic activation by the early coherent burst generated by high-frequency PhMNs may be necessary to prime it to overcome its initial inertia. We have also demonstrated the existence of a prominent role for local intraspinal inhibitory mechanisms in shaping phrenic pattern formation. The objective of this review is to relate and synthesize recent findings with those of previous studies with the aim of demonstrating that the phrenic nucleus is a region of active local processing, rather than a passive relay of descending inputs.

De la terre à la table : renforcer les compétences des agriculteurs ...

International Development Research Centre (IDRC) Digital Library (Canada)

De la terre à la table : renforcer les compétences des agriculteurs urbains en organisation et en mise en marché (Moyen-Orient et Afrique du Nord). Le réseau ... Stichting International Network of Resource Centres on Urban Agriculture and Food Security. Pays d' institution. Pays-Bas. Site internet. http://www.ruaf.org ...

CompTIA Network+ Certification Study Guide, Exam N10-004

CERN Document Server

Shimonski, Robert

2009-01-01

CompTIA's Network+ certification is a globally-recognized, vendor neutral exam that has helped over 235,000 IT professionals reach further and higher in their careers. The 2009 Network+ exam (N10-004) is a major update with more focus on security and wireless aspects of networking. Our new study guide has been updated accordingly with focus on network, systems, and WAN security and complete coverage of today's wireless networking standards. As always this companion covers the core Network+ material including basic design principles, management and operation of a network infrastructure, and tes

Compósitos polímero-madeira preparados por polimerização in situ de metil metacrilato usando aditivos bifuncionais

Directory of Open Access Journals (Sweden)

Bruno Dufau Mattos

2015-12-01

Full Text Available Resumo O presente trabalho teve por objetivo a confecção de compósitos polímero-madeira por meio de polimerização in situ de metil metacrilato (MMA, utilizando ácido metacrílico (MAA e glicidil metacrilato (GMA como agentes de ligação e reticulação. Amostras de madeira de guapuruvu foram impregnadas em um sistema de vácuo e pressão e polimerizadas em estufa a 90°C por 10h, usando 1,5% de peroxido de benzoíla como catalisador. Os compósitos foram caracterizados por meio de testes de absorção de água e estabilidade dimensional, molhabilidade, ATR-IR, TGA, MEV e WPG. Os espectros de ATR-IR mostraram incrementos nas bandas a 1746, 1460, e 1145 cm–1, referentes as estruturas químicas dos polímeros dentro da madeira, confirmado posteriormente pelas imagens de MEV. A termogravimetria apontou reações químicas entre os copolímeros e a parede celular da madeira nos compósitos com GMA e MAA. Os compósitos preparados com MMA apresentaram incrementos acima de 50% nas propriedades higroscópicas e de estabilidade dimensional, entretanto a adição de GMA e MAA resultou em maiores incrementos nas mesmas propriedades, entre 66-90%.

Correlation of serum cartilage oligomeric matrix protein (COMP) and interleukin-16 (IL-16) levels with disease severity in primary knee osteoarthritis: A pilot study in a Malaysian population.

Science.gov (United States)

Das Gupta, Esha; Ng, Wei Ren; Wong, Shew Fung; Bhurhanudeen, Abdul Kareem; Yeap, Swan Sim

2017-01-01

The aim of this study was to investigate the correlations between serum cartilage oligomeric matrix protein (COMP), interleukin-16 (IL-16) and different grades of knee osteoarthritis (KOA) in Malaysian subjects. Ninety subjects were recruited comprising 30 with Kellgren-Lawrence (K-L) grade 2 KOA, 27 with K-L grade 3 KOA, 7 with grade 4 KOA, and 30 healthy controls. All subjects completed the Western Ontario and McMaster Universities Arthritis Index (WOMAC) questionnaire. Serum COMP and IL-16 levels were measured using ELISA and their values log transformed to ensure a normal distribution. There was no significant differences in levels of log serum COMP and IL-16 between healthy controls and KOA patients. There were no significant differences in the log serum COMP and IL-16 levels within the different K-L grades in the KOA patients. In KOA patients, log serum IL-16 levels significantly correlated with the WOMAC score (p = 0.001) and its subscales, pain (p = 0.005), stiffness (p = 0.019) and physical function (p<0.0001). Serum IL-16 levels were significantly higher in Malaysian Indians compared to Malays and Chinese (p = 0.024). In this multi-ethnic Malaysian population, there was no difference in serum COMP and IL-16 levels between healthy controls and patients with KOA, nor was there any difference in serum COMP or IL-16 levels across the various K-L grades of KOA. However, there were significant inter-racial differences in serum IL-16 levels.

Processamento de plásticos e materiais compósitos: comportamento mecânico de componentes em serviço

OpenAIRE

Capela, Carlos Alexandre Bento

2010-01-01

As vantagens dos materiais plásticos, tais como facilidade de processamento, baixo custo, alta produtividade e versatilidade, permite obter plásticos e materiais compósitos de matriz polimérica para um grande número de aplicações em engenharia. Os materiais compósitos são, actualmente, muito utilizados não só na indústria aeroespacial, mas, também, num crescente número de aplicações de Engenharia Mecânica, tais como componentes de máquinas, vasos de pressão, equipamentos industriais de proces...

Efeito do condicionamento ambiental nas propriedades de cisalhamento e viscoelásticas de compósitos híbridos metal-fibra

OpenAIRE

Damato, Cesar Augusto [UNESP

2010-01-01

O desenvolvimento da tecnologia dos compósitos híbridos, combinando laminados poliméricos reforçados com fibras longas e placas metálicas, normalmente ligas de alumínio, denominados de CHMF, tem como uma de suas finalidades formar um conjunto de materiais que combine elevados valores de resistência mecânica, resistência ao impacto, rigidez e baixa massa específica. Essa combinação de propriedades torna os CHMF particularmente atrativos como substituintes das ligas metálicas e dos compósitos t...

Avaliação dos modos de falha sob impacto de compósitos de matriz polimérica reforçados por fibras

Directory of Open Access Journals (Sweden)

Marcelo M. M. Naglis

1998-03-01

Full Text Available RESUMO: Neste trabalho é feita uma avaliação dos modos de falha de compósitos de matriz polimérica reforçados por fibras de vidro, carbono ou aramida, submetidos a carregamento dinâmico. Os compósitos unidirecionais analisados foram fabricados por prensagem e cura à vácuo de lâminas de pré-impregnados. A energia total absorvida na fratura mostrou uma correlação inversamente proporcional ao módulo elástico das fibras usadas como reforço. Os compósitos com fibras de carbono falharam de um modo frágil. Para estes compósitos o comportamento ao impacto pode ser modelado usando-se uma análise puramente elástica. Para os compósitos com fibras de vidro a falha foi controlada por um mecanismo misto de cisalhamento ao longo da interface fibra-matriz e tensão normal trativa atuando perpendicularmente às fibras. O modelo elástico empregado para simular o comportamento ao impacto subestima a energia absorvida por estes compósitos, porém, a diferença entre os valores experimentais e os calculados não ultrapassou 20 %. A falha dos compósitos com fibras aramidas foi atribuída, principalmente, ao componente de tensão trativa atuando perpendicularmente às fibras. Nestes compósitos foi observado arrancamento superficial nas fibras aramidas e o comportamento ao impacto não obedece o modelo elástico empregado.ABSTRACT: In this work an evaluation of the fracture mode of fiber reinforced resin matrix composites submitted to three point bending dynamic impact testing was undertaken. The unidirectional glass, carbon and aramid fiber-epoxy matrix composites used were fabricated by vacuum bagging prepreg laminas. The energy absorbed to fracture the composites had an inverse correlation to the fibres' elastic modulus. The carbon fiber composites failed in a brittle mode. The analysis of the fracture surfaces showed that for the glass fiber composites, the failure is controlled by a coupled mechanism of shear along the fiber

Efeito de aditivos desaerantes nas características de compósitos de epóxi/fibras de vidro

Directory of Open Access Journals (Sweden)

Alexsandro Oliveira

2014-01-01

Full Text Available A presença de vazios é um importante fator a afetar as propriedades de compósitos poliméricos. Existem várias causas para a formação de vazios, entre elas, o aprisionamento de gás (frequentemente gás úmido durante o processo de impregnação dos reforços fibrosos com resina e os voláteis gerados durante a formulação da resina. A quantidade de bolhas de ar aprisionadas pode ser, por vezes, reduzida se o sistema de resina é sujeito a um processo de desgaseificação por vácuo ou pelo uso de aditivos químicos especiais. O objetivo deste trabalho é investigar o efeito de um agente desaerante nas propriedades finais de compósitos de resina epóxi moldados pelo processo de RTM utilizando como reforço mantas e tecidos de fibras de vidro. Os compósitos produzidos foram avaliados quanto as suas propriedades de tração, flexão, dureza, short beam e análise dinâmico mecânica (DMA. Em geral, a utilização do aditivo desaerante não provocou alterações significativas nas propriedades mecânicas, tais como resistência e módulo de tração e flexão, as quais são determinadas principalmente pelo tipo e fração volumétrica de fibras. Contudo, os resultados de resistência ao cisalhamento e de dureza mostram um efeito positivo com a inclusão do agente desaerante, levando à melhora na qualidade dos compósitos.

Influência de Negro de Fumo Modificado com Polianilina na Estrutura de Compósitos com Poli(Fluoreto de Vinilideno

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Zucolotto Valtencir

2002-01-01

Full Text Available Compósitos condutores elétricos a base de poli(fluoreto de vinilideno (PVDF e negro de fumo modificado com polianilina (Eeonomer® foram preparados através do processamento por fusão. Resultados de reometria de torque indicaram que a presença de polianilina no negro de fumo é vantajosa ao processamento por fusão, reduzindo a viscosidade do fundido em comparação com a aditivação com negro de fumo puro. Compósitos contendo acima de 5% em peso de Eeonomer® apresentaram condutividade da ordem de 10-2 S/cm. Esse valor se manteve estável mesmo após tratamento térmico a 150degreesC por 170 h em atmosfera ambiente. Análises por calorimetria diferencial de varredura (DSC e difração de Raios-X mostraram que o tipo e a quantidade de Eeonomer®, assim como a taxa de resfriamento da amostra, podem afetar a temperatura de fusão, o grau de cristalinidade e a fase cristalina do PVDF presente no compósito.

Resistência ao Cisalhamento Interlaminar de Compósitos com Resina Epóxi com Diferentes Arranjos das Fibras na Presença de Vazios

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Costa Michelle L.

2001-01-01

Full Text Available A presença de vazios em compósitos estruturais pode ter efeitos significativos. Em geral, os vazios diminuem a resistência estática e a vida em fadiga de laminados. Essa influência é bastante pronunciada na resistência ao cisalhamento interlaminar, compressão, entre outras, onde as propriedades mecânicas da matriz exercem maior influência sobre o comportamento do compósito. O presente artigo descreve o estudo do efeito da porosidade na resistência ao cisalhamento interlaminar de sistemas de compósitos de tecido e tape (fitas unidirecionais de carbono aglutinados com matriz epóxi. Os laminados foram produzidos de maneira semelhante, bem como o processo de introdução de vazios (na faixa de 0a 12% de porosidade.Os compósitos foram avaliados por análises microscópicas e inspeção ultra-sônica e os valores de atenuação medidos foram convertidos em coeficientes de absorção para permitir uma normalização dos dados. O critério de fratura de Mar-Lin apresentou bom ajuste, mostrando-se adequado para o estudo de porosidade em compósitos. Por meio desse critério foi determinado que somente os laminados com porosidade acima de 0,9% para tecido de carbono/epóxi e acima de 0,75% para laminados de tape de carbono/epóxi é que apresentam redução de suas propriedades mecânicas

Influência do tratamento químico da fibra de bananeira em compósitos de poli(etileno-co-acetato de vinila com e sem agente de expansão

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Matheus V. G. Zimmermann

2014-01-01

Full Text Available Neste trabalho foi avaliada a influência do tratamento alcalino na fibra de bananeira (FB e seu uso como agente de reforço em compósitos expandidos de poli(etileno-co-acetato de vinila - EVA. O processo de mistura dos compósitos ocorreu em um misturador de rolos aberto e após conformados e expandidos em uma prensa aquecida com moldes de volumes variáveis. Os compósitos foram avaliados por suas propriedades mecânicas, térmicas e morfológicas. Os resultados indicam que o tratamento alcalino promove a extração de componentes menos estáveis na FB, tais como a lignina, hemicelulose, ceras e óleos de baixo peso molecular. O uso da FB nos compósitos proporciona um decréscimo das propriedades mecânicas de resistência à tração e rasgo em relação ao EVA puro devido a moderadas propriedades de interface polímero-fibra. Nos compósitos expandidos, as propriedades mecânicas decrescem com a diminuição da densidade em função da maior presença de espaços vazios no interior dos compósitos, porém as propriedades mecânicas específicas de resistência ao rasgo apresentaram melhores resultados com 10 pcr de FB em todos os moldes utilizados.

Modèles et méthodologies d’analyse des compétences. Le double éclairage des pratiques et des recherches de Hajjar et Baubion-Broye

Directory of Open Access Journals (Sweden)

Jacques Leplat

2005-11-01

Full Text Available Le thème des compétences est d’actualité et de nombreuses disciplines se sentent concernées par son étude, notamment différentes spécialités de la psychologie, de l’ergonomie et de la sociologie. Octares témoigne de cet intérêt puisqu’il a déjà édité deux ouvrages sur ce thème : Leplat, J. et de Montmollin, M. (eds. (2001. Les compétences en ergonomie. Recueil de textes. Dupray, A., Guitton, C. & Monchatre, S. (eds.. (2003. Réfléchir la compétence. Approches sociologiques, juridiques, éco...

Avaliação das propriedades mecânicas e morfológicas de compósitos de PEAD com pó de Pinus taeda e alumina calcinada

Directory of Open Access Journals (Sweden)

Karine Grison

2015-08-01

Full Text Available ResumoNeste estudo foram desenvolvidos compósitos utilizando PEAD, pó de madeira (Pinus taeda, alumina calcinada e dois diferentes tipos de agentes compatibilizantes para avaliação das propriedades morfológicas e mecânicas dos mesmos. Para aumentar a interação entre a matriz polimérica e o pó de madeira foram utilizados 2% de polietileno graftizado com anidrido maleico em todas as formulações. Para efeito comparativo foi desenvolvida uma formulação com viniltrietoxisilano como compatibilizante para a alumina calcinada. O teor de cargas variou de 4% a 33% para os compósitos de carga única e mantiveram o percentual de 28% para os compósitos com as duas cargas. A interação entre a matriz polimérica e as cargas, proporcionada pelo agente compatibilizante anidrido maleico, foi observada nas micrografias da interface da matriz/carga. A utilização do silano não proporcionou efeito adicional nas propriedades mecânicas dos compósitos. Os compósitos isentos de alumina apresentaram maior resistência à tração, porém na resistência à flexão a presença da alumina contribuiu para o aumento desta propriedade provavelmente devido à pequena interação existente entre a interface do seu grão e a matriz polimérica.

Structure Identification Using High Resolution Mass Spectrometry Data and the EPA’s CompTox Chemistry Dashboard (EAS)

Science.gov (United States)

The iCSS CompTox Dashboard is a publicly accessible dashboard provided by the National Center for Computation Toxicology at the US-EPA. It serves a number of purposes, including providing a chemistry database underpinning many of our public-facing projects (e.g. ToxCast and ExpoC...

Chenu F. (2015). L’évaluation des compétences professionnelles. Une mise à l'épreuve des notions et présupposés théoriques sous-jacents

OpenAIRE

Wittorski, Richard

2016-01-01

Dans son ouvrage intitulé L’évaluation des compétences professionnelles, Florent Chenu s’intéresse à une question « chargée » tant sur le plan scientifique (définitions multiples du terme compétence, souvent aujourd’hui considéré comme un « mot valise ») que sur le plan social (des enjeux et débats sociaux vifs concernant les modalités d’évaluation des compétences et, au-delà, concernant la façon de les reconnaître dans les milieux du travail). Dans ce contexte particulier, proposer une publi...

Resposta tecidual ao compósito 50% hidroxiapatita: 50% poli-hidroxibutirato para substituição óssea em coelhos Tissue response to the composite 50% hydroxyapatite: 50% polyhydroxybutyrate for bone substitution in rabbits

Directory of Open Access Journals (Sweden)

E.C. Carlo

2009-08-01

Full Text Available Avaliaram-se a biocompatibilidade, a osseointegração, a osseocondução e a biodegradação de compósitos de 50% hidroxiapatita (HAP-91® e 50% poli-hidroxibutirato. O compósito foi implantado em defeitos ósseos em 12 coelhos (grupo experimental, sendo comparado a defeitos não preenchidos (grupo-controle, de igual número. Os parâmetros clínicos dor, claudicação, infecção, deiscência e edema foram avaliados nos primeiros oito dias após a cirurgia e aos 45 e 90 dias. Radiografias foram realizadas aos oito, 45 e 90 dias após a cirurgia em quatro animais por grupo que, em seguida, foram submetidos à eutanásia para coleta de amostras destinadas a análises histológica e histomorfométrica. Não ocorreram diferenças entre os grupos para todos os parâmetros clínicos. Radiografias demonstraram um compósito com radiopacidade semelhante à do osso vizinho e contato direto entre osso e compósito aos 45 e 90 dias. Diferença significativa foi observada entre a porcentagem dos tecidos ósseo e conjuntivo dentro do defeito nos dias oito, 45 e 90, assim como na interface aos 45 e 90 dias. Foram observadas projeções dos tecidos ósseo e conjuntivo no interior do compósito e sinais de biodegradação na ausência de infiltrado inflamatório. Pode-se concluir que o compósito é biocompatível, osseocondutor, biodegradável e se integra ao tecido ósseo.The biocompatibility, osseointegration, osseoconductivity, and biodegradation of a 50-50% hydroxyapatite (HAP-91®-polyhydroxybutyrate were evaluated. The composite was implanted in bone defects of 12 rabbits (experimental group, being compared to unfilled defects (control group, 12 animals. The clinical parameters of pain, lameness, infection, dehiscence, and edema were evaluated during the first eight days and on the 45th and 90th days after surgery. Radiographs were taken in four animals per group at 8, 45, and 90 days after surgery, when animals were euthanized to collect samples for

Compósitos à base de gesso com resíduos de EVA e vermiculita Gypsum-based composites with EVA waste and vermiculite

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Marilia P. de Oliveira

2012-06-01

Full Text Available O gesso é um dos materiais de construção mais antigos de que se tem conhecimento. Algumas de suas propriedades lhes conferem vantagens, tais como resistência ao fogo e isolamentos térmico e acústico. Objetivou-se, com este trabalho, avaliar as propriedades físico-mecânicas de compósitos à base de gesso com a incorporação de resíduos da indústria de calçados, o etileno acetato de vinila (EVA e a vermiculita. O desenvolvimento desses compósitos tem como propósito a produção de elementos de revestimento para proteção térmica de alvenarias. Para determinar a influência dos teores de resíduo de EVA e vermiculita e da relação água/gesso nas propriedades massa específica aparente e nas resistências a flexão e a compressão, foram incorporados cinco diferentes percentuais desses materiais, combinados com três relações água/gesso. Os resultados foram analisados por meio da estatística multivariável e indicaram que a massa específica aparente de ambos os compósitos e a resistência à flexão do compósito com vermiculita, mostraram maior dependência da relação água/gesso; por sua vez, o percentual de agregado apresentou maior influência na resistência à flexão do compósito com EVA e na resistência a compressão de ambos os compósitos.Gypsum is one of the oldest known building materials. Some of its properties confer advantages such as fire resistance, thermal and acoustic insulation. This work aims to study the physical and mechanical properties of gypsum-based composite with the incorporation of residues from the footwear industry ethylene vinyl acetate (EVA and vermiculite. The aim to develop these composites is to produce components for thermal protection of masonry. To determine the influence of different residue levels of EVA and vermiculite, and the water/plaster ratio on the bulk density, flexural and compressive strength, five different percentages of these materials were incorporated combined with

Deployed Flight Test of the Iraqi Air Force Comp Air 7SLX (CA-7)

Science.gov (United States)

2014-02-28

been built with a castering nose wheel mounted to the engine mount, a simple yet effective design. The team purchased new engine mounts and castering ...nose wheels from Aero Comp Inc. to solve these problems on all the CA-7s they refurbished, which Fred Webster called “a pretty big modification .”22...from a Cessna 310. The UAE had made numerous other modifications .2 The United States Central Command Air Forces (CENTAF) was working with the

Effects of Dicto-Comp and Dictation on the Writing Skill of Female Adult Iranian EFL Learners

Science.gov (United States)

Adel, Rahil; Hashemian, Mahmood

2015-01-01

This study was an attempt to clarify and remind L2 learners/teachers of 2 kinds of writing: dicto-comp and dictation. We explored the effect of controlled writing on the accuracy of the writing of adult Iranian EFL learners. Prior to the study, the homogeneity of 30 adult EFL learners was checked through an OPT test. Thirty participants were…

The CompTox Chemistry Dashboard: a community data resource for environmental chemistry.

Science.gov (United States)

Williams, Antony J; Grulke, Christopher M; Edwards, Jeff; McEachran, Andrew D; Mansouri, Kamel; Baker, Nancy C; Patlewicz, Grace; Shah, Imran; Wambaugh, John F; Judson, Richard S; Richard, Ann M

2017-11-28

Despite an abundance of online databases providing access to chemical data, there is increasing demand for high-quality, structure-curated, open data to meet the various needs of the environmental sciences and computational toxicology communities. The U.S. Environmental Protection Agency's (EPA) web-based CompTox Chemistry Dashboard is addressing these needs by integrating diverse types of relevant domain data through a cheminformatics layer, built upon a database of curated substances linked to chemical structures. These data include physicochemical, environmental fate and transport, exposure, usage, in vivo toxicity, and in vitro bioassay data, surfaced through an integration hub with link-outs to additional EPA data and public domain online resources. Batch searching allows for direct chemical identifier (ID) mapping and downloading of multiple data streams in several different formats. This facilitates fast access to available structure, property, toxicity, and bioassay data for collections of chemicals (hundreds to thousands at a time). Advanced search capabilities are available to support, for example, non-targeted analysis and identification of chemicals using mass spectrometry. The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the Dashboard has been aggregated over the past 15 years by both manual and auto-curation techniques within EPA's DSSTox project. DSSTox chemical content is subject to strict quality controls to enforce consistency among chemical substance-structure identifiers, as well as list curation review to ensure accurate linkages of DSSTox substances to chemical lists and associated data. The Dashboard, publicly launched in April 2016, has expanded considerably in content and user traffic over the past year. It is continuously evolving with the growth of DSSTox into high-interest or data-rich domains of interest to EPA, such

Comparação do comportamento à flexão com restrições à deflexão de placas de compósitos de matriz polimérica epoxídica em função do tipo de fibra de reforço

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Morais Willy A. de

2003-01-01

Full Text Available Placas finas de compósitos de matriz polimérica epoxídica reforçada por fibras de vidro, carbono ou aramida, bem como placas de um compósito híbrido vidro-aramida, foram submetidas a ensaios de flexão. As condições de fixação dos corpos de prova foram tais que o ensaios foram realizados com deflexão restrita. Os resultados experimentais obtidos para a deflexão máxima dos compósitos puderam ser qualitativamente previstos usando-se o método de balanço de energia de Ritz. Os compósitos reforçados por fibras de carbono apresentaram os maiores valores de energia de iniciação e de força máxima, o que foi atribuído às altas propriedades intrínsecas das fibras. As propriedades específicas do compósito híbrido foram superiores às dos compósitos apenas com fibras de vidro ou fibras aramidas. Este efeito sinergístico indicou um projeto adequado na fabricação deste compósito. O modo de falha macroscópico de todos os compósitos foi semelhante. Na face frontal, a interação compósito - punção seguiu o comportamento previsto pela Lei de Hertz. Na face posterior, houve preferencialmente delaminação.

CompNanoTox2015: novel perspectives from a European conference on computational nanotoxicology on predictive nanotoxicology

Energy Technology Data Exchange (ETDEWEB)

Bañares, Miguel A. [Instituto de Catalisis y Petroleoquimica, ICP, CSIC, Madrid, Spain,; Haase, Andrea [German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Berlin, Germany,; Tran, Lang [Statistics and Toxicology Section, Institute of Occupational Medicine, Edinburgh, UK,; Lobaskin, Vladimir [School of Physics, University College Dublin, Dublin, Ireland,; Oberdörster, Günter [Department of Environmental Medicine, University of Rochester, Rochester, NY, USA,; Rallo, Robert [Departament d’Enginyeria Informatica i Matematiques, Universitat Rovira i Virgili, Tarragona, Spain,; Advanced Computing, Mathematics, and Data Division, Pacific Northwest National Laboratory, Richland, WA, USA,; Leszczynski, Jerzy [Interdisciplinary Nanotoxicity Center, Jackson State University, Jackson, MS, USA,; Hoet, Peter [Public Health, Unit Lung Toxicology, K. U. Leuven, Leuven, Belgium,; Korenstein, Rafi [Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel,; Hardy, Barry [Technology Park Basel, Douglas Connect GmbH, Basel, Switzerland,; Puzyn, Tomasz [Laboratory of Environmental Chemometrics, Faculty of Chemistry, University of Gdansk, Gdansk, Poland

2017-08-09

A first European Conference on Computational Nanotoxicology, CompNanoTox, was held in November 2015 in Benahavís, Spain with the objectives to disseminate and integrate results from the European modeling and database projects (NanoPUZZLES, ModENPTox, PreNanoTox, MembraneNanoPart, MODERN, eNanoMapper and EU COST TD1204 MODENA) as well as to create synergies within the European NanoSafety Cluster. This conference was supported by the COST Action TD1204 MODENA on developing computational methods for toxicological risk assessment of engineered nanoparticles and provided a unique opportunity for crossfertilization among complementary disciplines. The efforts to develop and validate computational models crucially depend on high quality experimental data and relevant assays which will be the basis to identify relevant descriptors. The ambitious overarching goal of this conference was to promote predictive nanotoxicology, which can only be achieved by a close collaboration between the computational scientists (e.g. database experts, modeling experts for structure, (eco) toxicological effects, performance and interaction of nanomaterials) and experimentalists from different areas (in particular toxicologists, biologists, chemists and material scientists, among others). The main outcome and new perspectives of this conference are summarized here.

Effet sur la compétitivité des réglementations relatives à la gestion des effluents

DEFF Research Database (Denmark)

Andersen, Mikael Skou

2004-01-01

Grâce à un regard approfondi sur le secteur laitier dans les pays de l'OCDE, cette étude permet de mieux analyser l'impact des subventions à l'agriculture et des politiques de l'environnement sur l'environnement et sur la compétitivité internationale des produits laitiers. Ce chapitre étudie les ...

Non-Radial Oscillation Modes of Superfluid Neutron Stars Modeled with CompOSE

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Prashanth Jaikumar

2018-03-01

Full Text Available We compute the principal non-radial oscillation mode frequencies of Neutron Stars described with a Skyrme-like Equation of State (EoS, taking into account the possibility of neutron and proton superfluidity. Using the CompOSE database and interpolation routines to obtain the needed thermodynamic quantities, we solve the fluid oscillation equations numerically in the background of a fully relativistic star, and identify imprints of the superfluid state. Though these modes cannot be observed with current technology, increased sensitivity of future Gravitational-Wave Observatories could allow us to observe these oscillations and potentially constrain or refine models of dense matter relevant to the interior of neutron stars.

Foraging dives by post-breeding northern pintails

Science.gov (United States)

Miller, Michael R.

1983-01-01

Dabbling ducks (Anatini), including Northern Pintails (Anas acuta), typically feed by “tipping-up” (Bellrose, Ducks, Geese, and Swans of North America, Stackpole Books, Harrisburg, Pennsylvania, 1976) in shallow water. Pintails are not as adapted for diving as members of Aythyini or Oxyurini (Catlett and Johnston, Comp. Biochem. Physiol. 47A:925-931, 1974); however, incidents of foraging dives by small numbers of pintails have been reported (Chapman et al., Br. Birds 52:60, 1959; Bourget and Chapdelaine, Wildfowl 26:55-57, 1975). This paper reports on forage diving by a flock of several hundred pintails. Ecological explanations are suggested to account for the behavior and comparisons with tip-up feeding are presented.

Usinabilidade de materiais compósitos poliméricos para aplicações automotivas

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Juan Carlos Horta Gutiérrez

2014-12-01

Full Text Available A cada dia o avanço tecnológico nos leva a encruzilhadas como a construção de veículos mais leves, com menor consumo de combustível e mais seguros. Neste sentido, materiais compósitos poliméricos são materiais usados atualmente em diferentes aplicações nas quais a leveza combinada com um alto módulo de elasticidade são características importantes. Poliamidas reforçadas com fibras de vidro se apresentam como materiais de grande futuro em aplicações automotivas. Desta forma, torna-se importante o estudo do comportamento deste tipo de material quando submetidos a processos de usinagem. Dentre os processos de usinagem o processo de furação é um dos mais utilizados nos componentes de material compósito. Neste trabalho será analisada a influência do avanço, da velocidade de corte e da geometria da ferramenta na força de avanço, pressão específica de corte e desvios dimensionais do furo realizado. Os testes foram realizados em poliamida sem reforço (PA6 e reforçada com 30% fibra de vidro (PA66-GF30 utilizando brocas de carbonetos sinterizados (K20 com ângulos de ponta diferente. Os resultados apontam claramente para a melhor usinabilidade do material reforçado em comparação ao sem reforço.

Compósito para fabricação de implantes reabsorvíveis para osteossíntese: avaliação da biocompatibilidade em coelhos Composite for the fabrication of resorbable implants for osteosynthesis: biocompatibility evaluation in rabbits

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Emily Correna Carlo

2009-02-01

Full Text Available A biocompatibilidade, a osseointegração e a reabsorção de compósitos contendo 10% de hidroxiapatita (HAP-91® e 90% de polihidroxibutirato foram analisadas após implantação em defeitos ósseos em coelhos. Foram obtidos dados clínicos, radiográficos, histológicos e histomorfométricos aos oito, 45 e 90 dias após a realização da cirurgia, sendo os resultados comparados aos de defeitos não-preenchidos. Não foram observadas diferenças significativas entre os grupos para os parâmetros clínicos avaliados. Radiografias demonstraram o compósito em contato direto com osso aos 45 e 90 dias. Tecido ósseo se formou normalmente no defeito e na interface com o material, quando comparado ao controle. Não foi observado infiltrado inflamatório. Em todos os dias, a porcentagem de tecido ósseo foi maior que a de tecido conjuntivo (P=0,001 aos 8 e 45 dias e 0,022 aos 90 dias dentro dos defeitos. Foram observados tecidos ósseo e conjuntivo na interface com o compósito, sendo o último significativamente maior que o primeiro aos 90 dias (P=0,004. Foram observados sinais de reabsorção do compósito: células gigantes na superfície de fragmentos do compósito separados do bloco original. Portanto, pode-se concluir que o compósito é biocompatível em coelhos, reabsorvível e se integra ao tecido ósseo.Biocompatibility, osseointegration, and resorption of a 10% hydroxyapatite (HAP-91® - 90% polyhydroxybutyrate composite were analyzed after implantation in rabbits´ bone defects. Clinical, radiographic, histologic and histomorphometric data were collected on the 8th, 45th, and 90th days after surgery and the results were compared to those of unfilled defects. No significant differences between groups for the evaluated clinical parameters existed. Radiographs showed bone-composite direct contact. Bone tissue was formed normally in the defect and at the composite-tissue interface when compared to the control. No inflammatory infiltrated was

Dicósimo, Daniel y Simonassi, Silvia (comp., Trabajadores y empresarios en la Argentina del siglo XX: indagaciones desde la historia social

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Valeria Ianni

2013-01-01

Full Text Available Dicósimo, Daniel y Simonassi, Silvia (comp., Trabajadores y empresarios en la Argentina del siglo XX: indagaciones desde la historia social, Prohistoria ediciones, Rosario, 2011 (194 págs..

Security Administrator Street Smarts A Real World Guide to CompTIA Security+ Skills

CERN Document Server

Miller, David R

2011-01-01

A step-by-step guide to the tasks involved in security administration If you aspire to a career in security administration, one of your greatest challenges will be gaining hands-on experience. This book takes you through the most common security admin tasks step by step, showing you the way around many of the roadblocks you can expect on the job. It offers a variety of scenarios in each phase of the security administrator's job, giving you the confidence of first-hand experience. In addition, this is an ideal complement to the brand-new, bestselling CompTIA Security+ Study Guide, 5th Edition o

The US EPA CompTox Chemistry Dashboard as a source of data to fill data gaps for chemical sources of risk

Science.gov (United States)

Chemical risk assessment is both time-consuming and difficult because it requires the assembly of data for chemicals generally distributed across multiple sources. The US EPA CompTox Chemistry Dashboard is a publicly accessible web-based application providing access to various da...

32 CFR 651.14 - Integration with Army planning.

Science.gov (United States)

2010-07-01

... Religious Freedom Act. (7) Fish and Wildlife Coordination Act. (8) Comprehensive Environmental Response... 12898, 3 CFR, 1994 Comp., p. 859). (14) Indian Sacred Sites (Executive Order 13007, 3 CFR, 1996 Comp., p...

Real-time prediction of Physicochemical and Toxicological Endpoints Using the Web-based CompTox Chemistry Dashboard (ACS Fall meeting) 10 of 12

Science.gov (United States)

The EPA CompTox Chemistry Dashboard developed by the National Center for Computational Toxicology (NCCT) provides access to data for ~750,000 chemical substances. The data include experimental and predicted data for physicochemical, environmental fate and transport and toxicologi...

Corticosterone release in oxytocin gene deletion mice following exposure to psychogenic versus non-psychogenic stress.

Science.gov (United States)

Amico, Janet A; Cai, Hou-ming; Vollmer, Regis R

2008-09-19

Both anxiety-related behavior [J.A. Amico, R.C. Mantella, R.R. Vollmer, X. Li, Anxiety and stress responses in female oxytocin deficient mice, J. Neuroendocrinol. 16 (2004) 1-6; R.C. Mantella, R.R. Vollmer, X. Li, J.A. Amico, Female oxytocin-deficient mice display enhanced anxiety-related behavior, Endocrinology 144 (2003) 2291-2296] and the release of corticosterone following a psychogenic stress such as exposure to platform shaker was greater in female [J.A. Amico, R.C. Mantella, R.R. Vollmer, X. Li, Anxiety and stress responses in female oxytocin deficient mice, J. Neuroendocrinol. 16 (2004) 1-6; R.C. Mantella, R.R. Vollmer, L. Rinaman, X. Li, J.A. Amico, Enhanced corticosterone concentrations and attenuated Fos expression in the medial amygdala of female oxytocin knockout mice exposed to psychogenic stress, Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 (2004) R1494-R1504], but not male [R.C. Mantella, R.R. Vollmer, J.A. Amico, Corticosterone release is heightened in food or water deprived oxytocin deficient male mice, Brain Res. 1058 (2005) 56-61], oxytocin gene deletion (OTKO) mice compared to wild type (WT) cohorts. In the present study we exposed OTKO and WT female mice to another psychogenic stress, inserting a rectal probe to record body temperature followed by brief confinement in a metabolic cage, and measured plasma corticosterone following the stress. OTKO mice released more corticosterone than WT mice (Pstress. In contrast, if OTKO and WT female and male mice were administered insulin-induced hypoglycemia, an acute physical stress, corticosterone release was not different between genotypes. The absence of central OT signaling pathways in female mice heightens the neuroendocrine (e.g., corticosterone) response to psychogenic stress, but not to the physical stress of insulin-induced hypoglycemia.

Compósitos de Borracha Natural com Compostos Condutivos à Base de Negro de Fumo e Polímero Condutor Natural Rubber Composites with Conductive Compounds based on Carbon Black and Conducting Polymers

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Marinalva A. dos Santos

2001-09-01

Full Text Available Neste trabalho foram desenvolvidos compósitos condutores elétricos de borracha natural contendo negro de fumo e compostos condutivos baseados em polímeros condutores (Eenomer®. Os compósitos foram processados a quente num reômetro de torque HAAKE e moldados por prensagem. Foram obtidas placas homogêneas, flexíveis e com ótimo acabamento superficial. Os compósitos foram analisados pelas medidas de torque no processamento, medidas de condutividade elétrica, análise termogravimétrica (TGA, calorimetria diferencial de varredura (DSC e ensaios de tração. Estes compósitos apresentaram valores de condutividade elétrica entre 10-7 a 10-1 S/cm, dependendo do tipo de negro de fumo ou composto condutivo utilizado e da quantidade destes no compósito. A análise térmica demonstrou que os compósitos são termicamente estáveis até cerca de 300°C. Os compostos condutivos atuam como reforço para a borracha natural melhorando suas propriedades mecânicas sem perder significativamente sua flexibilidade.In this work, electrically conducting composites of natural rubber with carbon black and natural rubber with conductive compounds containing electrically conducting polymers (Eenomer® were developed. The composites were processed in a torque reometer HAAKE and then hot pressed. Homogeneous and flexible plates were obtained with excellent surface finish. The composites were analysed by the torque measurement during processing, electrical conductivity, thermogravimetric analysis (TGA, differential scanning calorimetric (DSC and mechanical analysis. Conductivity in the order of 10-7 to 10-1 S/cm were achieved, depending on the type of carbon black or conductive compound used and their content in the composite. Thermal analysis demonstrated that the compounds are thermally stable until 300°C. The conductive compounds act as reinforcements in the natural rubber matrix, improving its mechanical properties without significant loss on its

Compósito de colágeno com silicato e hidroxiapatita como material para endodontia: preparação e caracterização = Collagen composite with silicate and hydroxyapatite as endodontic material: preparation and characterization

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E'Gues, Miguel Antônio Menezes

2008-01-01

Full Text Available Objetivo: Este trabalho teve por objetivo preparar e caracterizar um novo compósito de colágeno com silicato e hidroxiapatita que possa vir a ser utilizado como material endodôntico em capeamento pulpar direto e em pulpotomia. Metodologia: Os materiais utilizados como matéria-prima foram colágeno do tipo I na forma aniônica, silicato (cimento Portland Branco e hidroxiapatita sintetizada. Estes materiais foram misturados em proporções variadas de modo a obter um material compósito na forma de pasta. Os materiais obtidos foram caracterizados por técnicas de calorimetria exploratória diferencial, termogravimetria, microscopia eletrônica de varredura (MEV, espectrometria de dispersão de energia de Raios-X e espectroscopia na região do infravermelho. Resultados: A presença de colágeno no compósito foi demonstrada por transições térmicas típicas daquelas encontradas para o colágeno do tipo I (~48ºC, independentemente da proporção utilizada, e também por imagens de MEV, onde as fibras colagênicas também puderam ser observadas interligando as partículas de silicato. A composição química de todos compósitos de colágeno foi praticamente idêntica à do silicato utilizado. Conclusão: Os resultados mostraram que a estrutura da matriz de colágeno nos compósitos testados não foi alterada. Esta é uma característica importante para a utilização em endodontia do material compósito proposto, objetivando uma reparação tecidual de forma "mais natural"

Tutorat à distance et développement des compétences professionnelles des futurs enseignants d’anglais langue seconde

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Mariane Gazaille

2011-03-01

Full Text Available S’insérant au cœur du processus d’enseignement et définissant l’intervention éducative, l’enseignant joue un rôle crucial dans tout système d’éducation. La qualité de la formation des maîtres (FM prend ici toute son importance en ce qu’elle vise à former des enseignants professionnels compétents. Pourtant, malgré la révision des programmes de FM, avance-t-on encore aujourd’hui que davantage pourrait être fait pour rapprocher théorie et pratique en FM. La présente étude vise à documenter cette question en s’intéressant aux effets d’un projet expérimental de tutorat inter-ordre2 à distance comme outil de formation pour les futurs enseignants de langues secondes. Les apprentissages rapportés sont classifiés puis comparés aux 12 compétences professionnelles (CP qui orientent la FM au Québec (Canada. Les résultats suggèrent que le tutorat à distance permet le développement intégré de plusieurs composantes des CPs visées en FM et la conscientisation des futurs enseignants vis-à-vis de celles-ci.Shaping and defining the instruction process, teachers play a pivotal role in any education system. In this perspective, the quality of teacher education is an issue of high importance in that it aims at training professional and competent teachers. Yet, and in spite of the revisions teacher training programs have undergone, it seems that more could be done to bring theory and practice closer in the field of teacher education. The current study aimed at documenting the question by studying the impacts of an experimental cross-level distance tutoring project on second language student teachers’ learning. Learning reported is first grouped and then contrasted to the 12 core professional competencies that orientate teacher training programs in Québec (Canada. Results suggest that distance tutoring allows for the integrated development of a number of features from different professional competencies as well as

Eugeniusz Misiło, comp. and ed., with an intro. Akcja “Wisła” 1947: Dokumenty i materiały.

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Jerzy Borzęcki

2016-02-01

Full Text Available Eugeniusz Misiło, comp. and ed., with an intro. Akcja “Wisła” 1947: Dokumenty i materiały. Warsaw: Archiwum Ukraińskie and Management Academy Group, 2012. 1246 pp. Illustrations. Maps. Documents section. Appendices section. Biographies sections. Miscellaneous lists. English-language summary. Indexes. Cloth.

Compósitos SiCf /SiC utilizados em sistemas de proteção térmica SiCf /SiC composites for thermal protection systems

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M. Florian

2005-09-01

Full Text Available Compósitos de carbeto de silício (SiC reforçado com fibras de carbeto de silício (SiCf são materiais candidatos em potencial para utilização em sistemas de proteção térmica em altas temperaturas devido principalmente à boa condutividade térmica na direção da fibra e muito baixa condutividade térmica na direção transversal à fibra, alta dureza, estabilidade térmica e à corrosão por oxidação. O compósito SiCf/SiC possui uma matriz de SiC reforçada com fibras contínuas policristalinas de SiC e é obtido por reações de conversão em altas temperaturas e atmosfera controlada, utilizando o compósito carbono/carbono como precursor. O processo de Reação Química em Vapor (CVR foi utilizado para a fabricação de compósitos SiCf/SiC com alta pureza na fase de SiC-beta. O compósito precursor de carbono/carbono foi fabricado com fibra de carbono não estabilizada e matriz carbonosa derivada da resina fenólica na forma de carbono isotrópico. O compósito convertido exibiu uma densidade de 1,75 g/cm³, com 40% de porosidade aberta e resistência à flexão de 80 MPa medida por ensaio flexão em 4 pontos. A área especifica medida pela técnica de BET é dependente da temperatura de conversão e das condições inicias do precursor de carbono, podendo chegar a 18 m²/g.Composites based on silicon carbide are potential candidate materials for thermal protection systems mainly due to its good thermal conductivity in fiber direction and very low transversal thermal conductivity, high hardness, corrosion and thermal resistance. SiCf/SiC composite presents a SiC matrix reinforced with SiC polycrystalline continuous fibers. The composite was obtained by conversion reactions at high temperature and controlled atmosphere from a carbon/carbon composite precursor. The CVR process was used to fabricate SiC /SiC composite with crystalline high-purity beta-SiC from a carbon-carbon precursor fabricated with non-stabilized carbon fiber and

Influência da relação estequiométrica resina/endurecedor em propriedades mecânicas de compósitos ternários hierárquicos resina - epóxi/tecido de fibra de carbono/nanotubos de carbono

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Kássio André Lacerda

2014-01-01

Full Text Available A produção de materiais que apresentem alto desempenho em suas aplicações exige avanços tecnológicos e científicos. Os elevados valores de resistência à tração e módulo de elasticidade, aliados à flexibilidade, baixa densidade e alta razão de aspecto, fazem dos nanotubos de carbono excepcionais candidatos para reforçar compósitos poliméricos. Preparamos por laminação sistemas compósitos ternários à base de resina epóxi/tecidos de fibra de carbono (para os binários, acrescendo nanotubos de carbono para os sistemas ternários. Os parâmetros estequiométricos do sistema epoxídico (valor de Phr e concentração de nanotubos de carbono empregado nos sistemas compósitos tiveram avaliadas suas morfologias (MEV, propriedades térmicas (TG e mecânicas (ASTM D790. Embora o sistema epoxídico com Phr 10,0 tenha apresentado uma maior estabilidade térmica, os compósitos ternários produzidos a partir do sistema com Phr 26,6 mostraram valores de tensão máxima e módulo de elasticidade até 8 vezes maiores que aqueles produzidos com o sistema Phr 10. A adição de nanotubos de carbono aos compósitos com Phr 26,6 resultou em ganhos adicionais de aproximadamente 38 e 15% na tensão máxima e no módulo de elasticidade, respectivamente. Esses resultados revelaram a limitação nos métodos de integralização de nanoestruturas a sistemas compósitos, onde as dispersões estão limitadas a uma série de fatores inerentes a interação química e/ou física durante a fabricação dos compósitos nanoestruturados.

Invention de soi et compétences à l’ère des réseaux sociaux

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Daniel Apollon

2011-06-01

Full Text Available Les réseaux sociaux en ligne encouragent de nouvelles approches de la compétence centrées sur la construction biographique de l’individu et l’invention de soi. Ce nouvel art de faire des « produsagers », répond au besoin d’inventer une réponse individuelle et collective au sentiment aliénant de vacuité des sociétés post-industrielles et post-traditionnelles. Combinant opposition et soumission aux éléments structurants et aliénants de cette modernité tardive, ces produsagers réactualisent diverses ruses, tactiques et schèmes immémoriaux déjà explorés par divers auteurs avant Internet. Sur cette toile de fond, l’auteur propose une réinterprétation plus large de la notion de compétence.Social media practices encourage new approaches and visions of competence focusing on the construction of individual biography and the "invention of oneself". The new "artful skills" of "produsers" address the need to invent individual and collective responses to the sense of alienating emptiness pervading postindustrial and posttraditional societies. Combining and submission and opposition to both structuring and alienating aspects of late modernity, these produsagers actualize various tricks, tactics and immemorial schemes already mapped by various authors before the Internet. On this backdrop the author proposes a broader reinterpretation of the concept of competence.

Les représentations des enseignants quant à leurs profils de compétences relatives à l’ordinateur : vers une théorie des TIC en éducation

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François Desjardins

2005-02-01

Full Text Available Depuis plusieurs années, dans la littérature, on peut sentir un besoin de préciser l’ensemble de connaissances et de compétences relatives aux ordinateurs nécessaires à l’enseignement et à l’apprentissage. Dans ce contexte, cette recherche vise à développer un modèle global qui permettrait de classer à la fois les outils, leurs usages, leurs incidences ainsi que les connaissances et compétences impliquées dans l’intégration des TIC en éducation de façon à pouvoir comprendre les diverses relations qui existent entre chacune de ces composantes. Une première opérationnalisation de ce modèle a donné lieu au développement d’un instrument permettant de recueillir les représentations des enseignants quant à leurs compétences. Cet article présente le modèle élaboré, le questionnaire qui en a découlé et les résultats des premières analyses statistiques des profils recueillis auprès de plus de 600 enseignants francophones de l’Ontario.

Evaluar la Coordinación Motriz Global en Educación Secundaria: El Test Motor SportComp. [Motor co-ordination assessment in Secondary Education: The SportComp Test].

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Luis Miguel Ruiz-Perez

2017-07-01

Full Text Available El objetivo de este estudio fue el desarrollo y evaluación métrica del Test Motor SportComp, instrumento diseñado para ayudar a los profesores de educación física en la evaluación de la coordinación motriz global de sus alumnos de Educación Secundaria. En la actualidad no existen tests que evalúen la coordinación motriz de forma válida y fiable y que puedan ser empleados por el profesorado de educación física en el contexto de sus clases de manera rápida y económica. El presente test se construyó a partir de una revisión de la literatura científica sobre medición motriz entre los 12 y 17 años. La validez de contenido de las pruebas empleadas fue evaluada por expertos y las pruebas seleccionadas fueron aplicadas a 5732 escolares de estas edades. Se analizaron los resultados mediante la técnica de componentes principales que permitió la extracción de un solo factor formado por 5 tareas motrices relacionadas con la coordinación motriz global. El Coeficiente de Correlación Intraclase (CCI permitió obtener una fiabilidad test-retest de (CCI=0,91. Asimismo, mostró una satisfactoria validez criterial con la batería MABC-2 uno de los más reconocidos para la detección de problemas de coordinación motriz. Las propiedades métricas del presente test son muy satisfactorias y ofrecen buenas posibilidades para ser empleado por los profesores de educación física en sus clases por su bajo coste económico, poco tiempo de aplicación reclamado y poseer normas ajustadas por edad y sexo. Asimismo, este test ofrece el potencial de poder servir para detectar a los alumnos con sospecha de poseer problemas de coordinación motriz y por lo tanto contribuir a la mejora de los programas de educación física que palíen esta condición. Abstract The purpose of this study was the development and metric evaluation of the SportComp Motor Test, an instrument designed to aid physical education teachers in the assessment of gross motor

Impregnação de filmes do compósito de policarbonato (PC e sílica-gel (Si com corante fotocrômico em fluido supercrítico - DOI: 10.4025/actascitechnol.v32i1.1999

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Fernanda de Almeida Fin de Lima

2009-12-01

Full Text Available O objetivo deste trabalho foi estudar a impregnação do corante fotocromático Reversacol Graphit® em filmes do compósito de policarbonato (PC e sílica-gel (Si, com a finalidade de obter aplicações em lentes fotocrômicas. Filmes de PC puros também foram impregnados nas mesmas condições, para verificar o efeito da adição de sílica-gel. Os filmes do compósito foram produzidos em proporções de Si:PC de 1:40 e 1:80 (m m-1, pelo método casting. Para a impregnação do corante Reversacol Graphit® nos filmes obtidos foi utilizado o processo supercrítico, pela sua eficiência e benefícios. A impregnação foi feita nos tempos de 15, 30, 45, 60, 90, 120, 150 e 180 min. A temperatura e a pressão adotadas foram de 60ºC e 120 bar. A quantidade de pigmento impregnado nos filmes de Si:PC – 1:40 e 1:80 (m m-1 foi de 29 e 23% de massa de corante por massa de compósito, respectivamente, e para o filme de PC puro foi de apenas 2,2% massa de corante por massa de compósito. Pelas análises térmicas, verificou-se que os filmes do compósito apresentaram maior estabilidade térmica. Pela técnica de microscopia eletrônica, observou-se que os filmes de PC puro e dos compósitos Si:PC – 1:40 e 1:80 (m m-1 apresentaram uma superfície lisa e homogênea.

Desenvolvimento de perfis extrudados de compósitos de polietileno de alta densidade com farinha de madeira

OpenAIRE

Cristiano Ribeiro de Santi

2009-01-01

A extrusão de perfis poliméricos apresenta algumas peculiaridades decorrentes do comportamento de fluxo destes materiais durante o processamento. Por outro lado, o projeto e construção de matrizes para perfis ainda tem sido mais resultado da experiência dos profissionais envolvidos do que um projeto de engenharia na sua essência. Neste trabalho, procurou-se aliar conceitos de engenharia auxiliada por computador ao comportamento reológico de compósitos termoplásticos reforçados com madeira no ...

Desenvolvimento e fabrico de compósitos de matriz polimérica com fibras naturais

OpenAIRE

Pereira, Júlio Miguel da Cruz Rodrigues

2017-01-01

Os compósitos de matriz polimérica com fibras curtas têm propriedades que se têm vindo a relevar como extremamente interessantes para uma ampla variedade de aplicações. Presentemente são fabricados, com recurso a diversas técnicas de processamento, desde componentes específicos para aplicação aeroespacial até artefactos de grande difusão. Estão na agenda mundial, os problemas com a poluição de materiais de origem plástica que fazem uso do petróleo como matéria-prima, a biodegradação destes...

Reforço em compósito de cimento portland através da adição nanotubos de carbono de paredes múltiplas

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Rogerio Daltro Knuth

2016-07-01

Full Text Available A pesquisa desenvolvida no presente trabalho esta embasada na aplicação da nanotecnologia a novos compósitos cimentícios, visando à melhoria das propriedades das argamassas. O objetivo do trabalho foi o de analisar o desempenho físico e mecânico e a ancoragem de uma argamassa de revestimento produzida com nanotubos de carbono de paredes múltiplas (NTCPM, adicionados na quantidade de 0,30% em relação à massa de cimento do compósito, comparativamente ao desempenho com uma argamassa industrializada. Para o presente estudo foi necessário funcionalizar e dispersar os NTCPM, utilizando-se os ácidos sulfúrico (H2SO4 e nítrico (HNO3, e a dispersão foi por ultrassom. Os NTCPM funcionalizados foram neutralizados com hidróxido de amônio (NH3. Foram realizados ensaios de caracterização física e mecânica no estado fresco e no estado endurecido nas argamassas de revestimento com NTCPM e industrializada e análise microestrutura. Os resultados obtidos indicam que a argamassa com NTCPM apresenta melhor desempenho que a argamassa industrializada, no tocante a densidade, consistência, viscosidade, resistência à tração e resistência a compressão axial. Palavras-chave: Argamassas de revestimento. Nanotubos de carbono. Compósitos. Propriedades físicas e mecânicas. Microestrutura.

SDN-controlled topology-reconfigurable optical mobile fronthaul architecture for bidirectional CoMP and low latency inter-cell D2D in the 5G mobile era.

Science.gov (United States)

Cvijetic, Neda; Tanaka, Akihiro; Kanonakis, Konstantinos; Wang, Ting

2014-08-25

We demonstrate the first SDN-controlled optical topology-reconfigurable mobile fronthaul (MFH) architecture for bidirectional coordinated multipoint (CoMP) and low latency inter-cell device-to-device (D2D) connectivity in the 5G mobile networking era. SDN-based OpenFlow control is used to dynamically instantiate the CoMP and inter-cell D2D features as match/action combinations in control plane flow tables of software-defined optical and electrical switching elements. Dynamic re-configurability is thereby introduced into the optical MFH topology, while maintaining back-compatibility with legacy fiber deployments. 10 Gb/s peak rates with <7 μs back-to-back transmission latency and 29.6 dB total power budget are experimentally demonstrated, confirming the attractiveness of the new approach for optical MFH of future 5G mobile systems.

Les compétences infirmières mobilisées dans un service d'oncologie pédiatrique pour répondre aux besoins de l'enfant et sa famille: travail de Bachelor

OpenAIRE

Alemanno, Gaëtan; Lorency, Vincent; Morf, Benjamin; Delajoux, Annie

2013-01-01

Dans ce travail de bachelor, nous nous intéressons aux compétences infirmières en onco-hématologie pédiatrique. En faisant cette recherche, nous mettons en évidences le vécu des parents dont l’enfant est malade, ainsi que leurs différents besoins ressentis, que ce soit de l’enfant ou des proches aidants. Nous identifions ces compétences en comparant, les actions et pratiques infirmières, avec le modèle de Calgary.

Estudo de propriedades dinâmico-mecânicas de um compósito aeronáutico de CFRP com fios de ligas com memória de forma embebidos

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Zoroastro Torres Vilar

2016-01-01

Full Text Available Resumo Este trabalho trata-se de um estudo experimental do comportamento de propriedades termomecânicas de um compósito ativo, obtido através da introdução de diferentes frações volumétricas de fios de uma liga NiTi com efeito de memoria de forma em uma matriz polimérica reforçada com fibras de carbono (CFRP. Para tal estudo, inicialmente fez-se uma análise do módulo elástico de um pré preg de CFRP aeronáutico com diferentes posições de ângulo de fibras de carbono, a fim de determinar a matriz mais adequada para a introdução de fios de NiTi para obter compósito ativo. Verificou-se que a matriz com fibras alinhadas a 15º apresenta-se como uma boa opção para a obtenção de compósitos ativos, sendo utilizada para a fabricação de amostras de CFRP/NiTi. As amostras tiveram seu potencial de ativação avaliado através da análise da variação do módulo de elasticidade com o aumento da temperatura usando a técnica de Análise Dinâmico-Mecânica (DMA. Através dos resultados obtidos, verificou-se a capacidade de ativação dos compósitos CFRP/NiTi, os quais apresentam variação positiva de módulo de elasticidade ao serem aquecidos acima da temperatura de transformação dos fios NiTi.

Influência da adição de uma carga nanoparticulada no desempenho de compósitos poliuretano/fibra de juta Influence of a nanoparticulate filler addition on the mechanical properties of polyurethane/jute fiber composites

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José R. A. Neto

2007-03-01

Full Text Available Neste trabalho as propriedades mecânicas de um compósito, formado a partir de uma matriz de poliuretano derivado do óleo de mamona e reforçada por um tecido tramado de juta, foram avaliadas. O efeito da adição de pequenos teores de bentonita cálcica e sódica sobre as propriedades mecânicas da matriz de poliuretano e de compósitos poliuretano/juta também foi investigado. Os resultados indicam que a incorporação de fibra de juta à matriz poliuretana promoveu melhora significativa nas propriedades sob tração dos compósitos. A adição de pequenos teores de argila à matriz alterou o desempenho mecânico dos compósitos, porém os resultados não foram os esperados. O compósito híbrido poliuretano/argila/fibra de juta, contudo, apresentou propriedades mecânicas superiores às dos compósitos reforçados unicamente com tecido de juta, o que indica uma atuação sinérgica dos reforços híbridos argila/juta.In this work the mechanical properties of polyurethane/jute fiber composites were evaluated as a function of fiber content and mineral filler addition. A polyurethane (PU derived from castor oil was used as the matrix and hessian cloth as reinforcement. The effect of the incorporation of small amounts of local clay (bentonite, in its calcium and sodium forms, on the mechanical properties of polyurethane/jute composites was also investigated. The results indicate that the tensile properties of the composites substantially increased with jute fiber addition and that although the mechanical properties of the matrix were affected by the addition of nanoparticulate clay, the improvement was not as expected. This was attributed to poor mixing and dispersion of the filler, which was confirmed by SEM. A synergistic effect was observed for the hybrid clay/jute fiber composites, with considerable improvement in the mechanical performance of the hybrid composites.

MED, COMP, multilayered and NEIN: an overview of multiple epiphyseal dysplasia

Energy Technology Data Exchange (ETDEWEB)

Lachman, Ralph S. [International Skeletal Dysplasia Registry, UCLA School of Medicine, Radiological Services, Department of Pediatrics, Los Angeles, CA (United States); International Skeletal Dysplasia Registry, Los Angeles, CA (United States); Krakow, Deborah; Cohn, Daniel H.; Rimoin, David L. [International Skeletal Dysplasia Registry, UCLA School of Medicine, Radiological Services, Department of Pediatrics, Los Angeles, CA (United States)

2005-02-01

This overview covers the group of disorders that presents radiographically as multiple epiphyseal dysplasia (MED). The disorders include ''classic MED'' (Ribbing and Fairbank types): MED that is caused by mutations in the cartilage oligomeric matrix protein (COMP), type IX collagen, and matrilin 3 genes (MATN3); and MED with multilayered patella, brachydactyly, and clubbed feet resultant from mutations in gene defect diastrophic dysplasia (DTDST). The recently identified gene/molecular abnormalities in these disorders have made more exact identification possible in many cases, although clinical testing is not always available. However, there are specific radiographic findings that allow the accurate diagnosis to be made, thus potentially guiding which molecular defect(s) should be investigated. The modes of inheritance of these distinct MED conditions are not identical. When a specific diagnosis is made, proper genetic counseling as well as prognostication, management issues and complications can be delineated to the patient and family. This review will include the mechanics of diagnostic and molecular triage for these disorders. (orig.)

Former aux TICE : entre compétences techniques et modèles pédagogiques

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Jacques Béziat

2012-01-01

Full Text Available Cette contribution discute des enjeux et des limites d’une formation aux compétences techniques attendues des futurs enseignants d’école primaire. Une formation est certainement nécessaire pour espérer voir des pratiques pédagogiques avec les TICE se développer en classe. Mais ce n’est qu’un des leviers pour leur intégration dans les pratiques scolaires. Une formation aux TICE suppose que l’on mette l’accent sur l’analyse de pratiques. Plus que de former « simplement » à l’usage pédagogique d’outils numériques, il est indispensable de former à la complexité de leurs enjeux intellectuels et pratiques.

Estudos das propriedades mecânicas e térmicas do polímero biodegradável poli-3-hidroxibutirato (PHB) e de compósitos PHB/pó de madeira.

OpenAIRE

Miriam Lúcia Chiquetto Machado

2008-01-01

O objetivo deste trabalho foi o estudo das propriedades mecânicas e térmicas do PHB e de compósitos de PHB/pó de madeira processados, reprocessados e irradiados. Foram preparados compósitos com PHB e pó de madeira com concentrações de PHB/pó de madeira de 90/10, 80/20 e 70/30 (m/m). Foram realizados ensaios de propriedades mecânicas, HDT, ponto de amolecimento Vicat, TGA e DSC. A incorporação do pó de madeira aumentou o grau de cristalinidade e a temperatura de cristalização do polímero, e no...

GeoComp-n, an advanced system for the processing of coarse and medium resolution satellite data. Part 2: biophysical products for Northern ecosystems

Energy Technology Data Exchange (ETDEWEB)

Cihlar, J. [Canada Centre for Remote Sensing, Natural Resources Canada, Ottawa, Ontario (Canada); Chen, J. [Canada Centre for Remote Sensing, Natural Resources Canada, Ottawa, Ontario (Canada); Univ. of Toronto, Dept. of Geography, Toronto, Ontario (Canada); Li, Z. [Canada Centre for Remote Sensing, Natural Resources Canada, Ottawa, Ontario (Canada); Univ. of Maryland, Dept of Meteorology, College Park, MD (United States)] [and others

2002-02-01

Effective use of satellite data for environmental monitoring requires consistent, high-throughput processing of large volumes of data as it is transformed from raw measurements to useful higher level products. 'GeoComp-n', the next generation of the Geocoding and Compositing System developed at the Canada Centre for Remote Sensing, Natural Resources Canada, was developed as a software solution to this challenge, for use with satellites that provide daily data for the landmass of Canada or comparably large areas. In this paper, the authors discuss the characteristics of the algorithms and methods used in the generation of GeoComp-n products. The theoretical basis and assumptions in the algorithms are described, and the quality of the products is discussed based on validation studies. Examples of a suite of products for Canada during one 10-day period illustrate the diversity and quality of observations for the terrestrial biosphere that may be derived frequently and over large areas from satellites. Issues related to quality assessment in a production environment are also discussed. (author)

GeoComp-n, an advanced system for the processing of coarse and medium resolution satellite data. Part 2: biophysical products for Northern ecosystems

International Nuclear Information System (INIS)

Cihlar, J.; Chen, J.; Li, Z.

2002-01-01

Effective use of satellite data for environmental monitoring requires consistent, high-throughput processing of large volumes of data as it is transformed from raw measurements to useful higher level products. 'GeoComp-n', the next generation of the Geocoding and Compositing System developed at the Canada Centre for Remote Sensing, Natural Resources Canada, was developed as a software solution to this challenge, for use with satellites that provide daily data for the landmass of Canada or comparably large areas. In this paper, the authors discuss the characteristics of the algorithms and methods used in the generation of GeoComp-n products. The theoretical basis and assumptions in the algorithms are described, and the quality of the products is discussed based on validation studies. Examples of a suite of products for Canada during one 10-day period illustrate the diversity and quality of observations for the terrestrial biosphere that may be derived frequently and over large areas from satellites. Issues related to quality assessment in a production environment are also discussed. (author)

Les effets sur la compétitivité internationale des réglementations relatives à la gestion des effluents d'élevage

DEFF Research Database (Denmark)

Andersen, Mikael Skou

2003-01-01

différences sensibles de compétitivité de la production porcine et d’une concurrence internationale croissante sur le marché de la viande de porc explique que l’on se préoccupe de la charge financière imposée par les politiques de l’environnement aux éleveurs, notamment en ce qui concerne la gestion des...

COMP report: CPQR technical quality control guidelines for low-dose-rate permanent seed brachytherapy.

Science.gov (United States)

Beaulieu, Luc; Radford, Dee-Ann; Eduardo Villarreal-Barajas, J

2018-03-14

The Canadian Organization of Medical Physicists (COMP), in close partnership with the Canadian Partnership for Quality Radiotherapy (CPQR) has developed a series of Technical Quality Control (TQC) guidelines for radiation treatment equipment. These guidelines outline the performance objectives that equipment should meet in order to ensure an acceptable level of radiation treatment quality. The TQC guidelines have been rigorously reviewed and field tested in a variety of Canadian radiation treatment facilities. The development process enables rapid review and update to keep the guidelines current with changes in technology. This article contains detailed performance objectives and safety criteria for low-dose-rate (LDR) permanent seed brachytherapy. © 2018 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

Les facteurs influançant les compétences des infirmiers et des infirmières en matière de soins spirituels dans un contexte de soins somatiques: une revue de littérature étoffée

OpenAIRE

Bédaton, Stéphanie; Hayoz, Marine; Schenevey Perroulaz, Eliane

2013-01-01

Les facteurs influençant les compétences des infirmiers et des infirmières en matière de soins spirituels dans un contexte de soins somatiques. Objectif : identifier la place de la spiritualité dans les soins et identifier les facteurs aidants et les obstacles qui influencent les compétences des infirmières dans le domaine de la spiritualité dans un contexte de soins somatiques.

Using semi-automated curation workflows to collect, organize, and curate the data and models necessary to support the EPA CompTox chemical dashboard (ACS Spring meeting)

Science.gov (United States)

With the increasing need to leverage data and models to perform cutting edge analyses within the environmental science community, collection and organization of that data into a readily accessible format for consumption is a pressing need. The EPA CompTox chemical dashboard is i...

Using the US EPA's CompTox Dashboard to support identification and screening of emerging organic contaminants in the environment (ACS Spring National meeting) 2 of 7

Science.gov (United States)

The US EPA’s iCSS CompTox Dashboard is a curated, publicly accessible resource provided by the National Center for Computational Toxicology (https://comptox.epa.gov). The Dashboard provides support for toxicology and risk assessment within and external to the EPA (including ToxC...

Classe de langue et compétence évaluative des enseignants : entre pratiques évaluatives et politique éducative

Directory of Open Access Journals (Sweden)

Mina Sadiqui

2014-12-01

Dans une dernière partie nous esquisserons, en nous basant sur une approche didactique, quelques repères qui permettraient à tout enseignant ou futur enseignant de repenser les éléments organisateurs d’un dispositif d’évaluation ,et donc de construire une compétence évaluative en classe de langue, si on veut vraiment mettre en place une nouvelle politique éducative relative à l’enseignement/apprentissage des langues ,en l’occurrence celle du FLE au lycée au Maroc.

Les pôles de compétitivité : le recours au modèle des clusters ?

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Jean Bouinot

2007-03-01

Full Text Available Introduction : définition d’un cluster En novembre 2004, le gouvernement a lancé un appel d’offre pour structurer des pôles de compétitivité que les praticiens français n’hésitent pas à qualifier de cluster, littéralement un rassemblement du type « bouquet de fleurs ». Pour une définition théorique on peut s’appuyer sur une comparaison avec le modèle du district industriel italien (MDII. Le district est spécialisé dans un produit donné (chaussures de sport à Montebelluna, le leader mondial e...

FoRSIC : De l'ingénierie des compétences à l'ingénierie des connaissances.

OpenAIRE

Ertzscheid , Olivier; Link-Pezet , Jo; Lacombe , Elisabeth

2002-01-01

FoRSIC [1] est un dispositif d'ingénierie des connaissances, qui s'ancre dans le champ de la formation à la recherche documentaire. Après avoir précisé le contexte théorique qui le sous-tend, nous décrirons ici les méthodologies qui nous ont permis de faire émerger des représenta-tions structurantes et partageables de ce domaine, à l'aide d'une ontologie des compétences docu-mentaires que nous relions au réseau sémantique du modèle de domaine.

Avaliação da Resistência Interlaminar do Compósito PEI/Fibras de Carbono Soldado pelo Método de Resistência Elétrica

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Jonas Frank Reis

Full Text Available Resumo: O presente trabalho tem como principal objetivo avaliar a efetividade do processo de soldagem por resistência elétrica em compósitos de matriz poli (éterimida reforçados com fibras contínuas de carbono, a partir do estudo das propriedades térmicas e mecânicas da junta soldada. Para a avaliação das propriedades térmicas, as amostras do material soldado foram submetidas às análises por termogravimetria e por análise termomecânica. Já com o intuito de se estudar a interface resultante da soldagem, estudos foram realizados a partir dos ensaios de cisalhamento ILSS e Iosipescu, assim como por End-Notched Flexure (ENF. Os resultados das análises térmicas em laminados de PEI/fibras de carbono não soldados mostram que o início da degradação para estes compósitos ocorre a 460 °C, e ainda é evidenciado que a temperatura de transição vítrea para amostras soldadas é aproximadamente 15% superior aos resultados provenientes de amostras não soldadas. Nos ensaios mecânicos mostram que houve um aumento de 32% e de 20%, respectivamente, nos resultados de cisalhamento interlaminar por ILSS e por Iosipescu nas amostras soldadas, quando estas são comparadas a amostras não soldadas. Os resultados do ensaio de ENF apresentam valores satisfatórios de tenacidade à fratura interlaminar nos compósitos soldados em relação aos valores encontrados em literatura.

SCIDAC Center for simulation of wave particle interactions CompX participation

Energy Technology Data Exchange (ETDEWEB)

Harvey, R.W. [CompX, Del Mar, CA (United States)

2017-11-14

beyond to achieve the needed physics, resolution, and/or statistics to address these issues. CompX provides computer codes and analysis for the calculation of the electron and ion distributions in velocity-space and plasma radius which are necessary for reliable calculations of power deposition and toroidal current drive due to combined radiofrequency and neutral beam at high injected powers. It has also contributed to ray tracing modeling of injected radiofrequency powers, and to coupling between full-wave radiofrequency wave models and the distribution function calculations. In the course of this research, the Fokker-Planck distribution function calculation was made substantially more realistic by inclusion of finite-width drift-orbit effects (FOW). FOW effects were also implemented in a calculation of the phase-space diffusion resulting from radiofrequency full-wave models. Average level of funding for CompX was approximately three man-months per year.

Compósitos Bioativos Obtidos a Partir da Inserção de Vidro Bioativo em Matriz de Poli(Metacrilato de Metila Bioactive Composites Obtained from Bioactive Glass Particles into Poly(Methyl Methacrylate

Directory of Open Access Journals (Sweden)

Paulo E. Silva Junior

2001-09-01

Full Text Available Várias biocerâmicas são capazes de se ligarem a tecidos vivos (bioatividade, no entanto apresentam propriedades mecânicas muito diferentes daquelas exibidas por tecidos naturais. Tal fato acaba por restringir o uso desses materiais em um mais extenso número de aplicações biomédicas. Compósitos de matriz polimérica reforçada com uma fase bioativa podem combinar o comportamento bioativo característico de algumas biocerâmicas com propriedades mecânicas próximas à de tecidos humanos. O presente trabalho tem como objetivo sintetizar e caracterizar compósitos de matriz polimérica reforçada por partículas de vidro bioativo. Os compósitos foram produzidos a partir da polimerização em massa de metacrilato de metila na presença de partículas de vidro bioativo (vidro de silicato de cálcio, fósforo e sódio. Partículas de vidro foram adicionadas ao monômero em diversas concentrações para permitir a variação das propriedades mecânicas e da bioatividade desses compósitos. A bioatividade dos materiais produzidos foi avaliada através de testes in vitro realizados a 37ºC em uma solução simuladora do fluido humano por períodos de tempo de 0 hora a 30 dias. Em seguida, os compósitos submetidos aos testes in vitro foram caracterizados por espectroscopia de infravermelho. O procedimento de síntese mostrou-se eficaz na produção de compósitos com diferentes frações volumétricas de partículas distribuídas homogeneamente pelo material. Os resultados dos testes in vitro revelaram a deposição de uma camada de hidroxiapatita carbonatada (HCA na superfície dos materiais, comprovando a bioatividade dos compósitos. Foi ainda observado que a cinética de deposição da camada de HCA pode ser controlada pela fração volumétrica da fase bioativa.Some bioceramics have the ability to bind to tissues but they show mechanical properties very different from the ones of natural tissues. This fact restricts the use of these

Apport de la théorie du sentiment d’autoefficacité pour le développement de la compétence technopédagogique des futurs enseignants

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Sonia Lefebvre

2015-01-01

Full Text Available Le texte s’intéresse à la formation technopédagogique des futurs enseignants, et plus précisément, aux pratiques à déployer en formation initiale pour accroître leur compétence professionnelle à intégrer les TIC. Les pratiques proposées prennent appui sur la théorie du sentiment d’autoefficacité d’Albert Bandura, ce sentiment pouvant influencer leur compétence à intégrer les TIC. Appuyé par des travaux empiriques, le texte aborde les sources susceptibles d’influencer l’autoefficacité à intégrer les TIC dans un cadre pédagogique et identifie des pistes d’action à envisager. Enfin, la réflexion amène à repenser les interventions des formateurs tant en formation initiale qu’en formation continue et à remettre en question, sur le plan empirique, les dispositifs de formation.

État des lieux de la Gestion prévisionnelle des Emplois et des Compétences dans le secteur de la métallurgie : cas de l'entreprise Duferco Coating de Beautor

OpenAIRE

Marie Amélie Cloez

2011-01-01

Ce mémoire traite de la gestion prévisionnelle des emplois et des compétences dans le secteur de la métallurgie, plus précisément au sein de l'entreprise Duferco Coating située à Beautor. Ce mémoire cible le secteur de la métallurgie parce qu'il fut l'un des premiers secteurs à mettre en place cette démarche. Depuis la loi de deux mille cinq, les entreprises de plus de trois cent salariés doivent mettre en place un accord GPEC qui leur permet de prévoir leurs besoins en termes de compétences ...

Diametral tensile strength of composite resins submitted to different activation techniques Resistência à tração diametral de compósitos resinosos submetidos a diferentes técnicas de ativação

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Denise Sá Maia Casselli

2006-09-01

Full Text Available The aim of this study was to evaluate the diametral tensile strength (DTS of composite resins submitted to different curing techniques. Four composite resins were tested in this study: Targis (Ivoclar, Solidex (Shofu, Charisma (Heraeus-Kulzer and Filtek Z250 (3M Espe. Sixty-four cylindrical specimens were prepared and divided into eight groups according to each polymerization technique (n = 8. The indirect composite resins (Targis and Solidex were polymerized with their respective curing systems (Targis Power and EDG-lux; Charisma and Filtek Z250 were light-cured with conventional polymerization (halogen light and additionally, with post-curing systems. Specimens were stored in artificial saliva at 37°C for one week. DTS tests were performed in a Universal Testing Machine (0.5 mm/min. The data were statistically analyzed by ANOVA and Duncan tests. The results were (MPa: Z250/EDG-lux: 69.04ª; Z250/Targis Power: 68.57ª; Z250/conventional polymerization: 60.75b; Charisma/Targis Power: 52.34c; Charisma/conventional polymerization: 49.17c; Charisma/EDG-lux: 47.98c; Solidex: 36.62d; Targis: 32.86d. The results reveal that the post-cured Z250 composite resin showed the highest DTS means. Charisma composite presented no significant differences when activation techniques were compared. Direct composite resins presented higher DTS values than indirect resins.O objetivo do trabalho foi avaliar a resistência à tração diametral (DTS de compósitos submetidos a diferentes técnicas de polimerização. Foram testados quatro compósitos neste estudo: Targis (Ivoclar, Solidex (Shofu, Charisma (Heraeus-Kulzer e Filtek Z250 (3M Espe. Foram confeccionados 64 corpos-de-prova cilíndricos, que foram divididos em 8 grupos de acordo com a técnica de polimerização (n = 8. Os compósitos indiretos (Targis e Solidex foram polimerizados com seus respectivos sistemas de ativação (Targis Power e EDG-lux; Charisma e Filtek Z250 foram fotoativados com polimeriza

Propriedades mecânicas de tração de compósitos poliéster/tecidos híbridos sisal/vidro Properties of polyester/hibrid sisal-glass fabrics

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Laura H. de Carvalho

2006-03-01

Full Text Available O desempenho e o custo de compósitos podem ser alterados por hibridização e, neste sentido, é relativamente comum o uso combinado de fibras e reforços minerais no desenvolvimento destes materiais. No presente trabalho o desempenho mecânico de compósitos poliéster insaturado/ tecidos híbridos sisal-vidro foram investigados em função do teor de fibra e direção do teste. Foram confeccionados três tecidos híbridos (com 30, 40 e 50% em peso de vidro com fios de sisal no urdume e fibras de vidro na trama. Os compósitos foram moldados por compressão à temperatura ambiente com os tecidos alinhados. Os resultados indicam que houve um aumento nas propriedades mecânicas de tração de todos os compósitos com o aumento do teor de fibras. Para os compósitos reforçados por tecidos com baixo teor de fibra de vidro, as propriedades tenderam a ser mais elevadas quando os testes foram conduzidos na direção do sisal, enquanto que para os tecidos com elevado teor de vidro, o oposto foi observado. Estes comportamentos foram associados ao teor de fibra de vidro na direção do teste e ao diâmetro das fibras de sisal. Em baixos teores de fibra o sisal agiria como inclusão ou defeito, prejudicando as propriedades mecânicas; em elevados teores as propriedades do vidro suplantariam os defeitos provocados pelo sisal.Hybridization can alter both mechanical performance and cost of polymer composites, and novel composite materials can be obtained by the combination of both fibrous and mineral reinforcements. In the present work the mechanical performance of unsaturated polyester/hybrid sisal-glass fabrics was determined as a function of fibre content and test direction. Three different hybrid fabrics (30, 40 and 50% w/w glass content with sisal strings in the warp and glass roving in the weft were hand weaved. Aligned fabric compression moulded composites were obtained at room temperature. The results showed enhanced properties with fibre content

How should collective and distributed skills be considered in professional skills management? Quelle prise en compte des compétences collectives et distribuées dans la gestion des compétences professionnelles ? Cómo tomar en cuenta las competencias colectivas y distribuidas en la gestión de las competencias profesionales ?

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Catherine Delgoulet

2008-05-01

Full Text Available The purpose of this paper is to discuss how collective and distributed skills are considered in a professional competence management system by associating sociological and ergonomic work approaches. Collective work in companies is currently paradoxical: on the one hand, its value is increased through various forms of cooperation, and on the other hand, it is restricted in its makeup and sustainability by new kinds of employment. However, the results of our study, carried out in a large industrial and retailing company in a high-risk sector, highlight that a “single” and individual professional competence management system is a partial system. Work contexts should take into account technical specialties, changes in populations, changes in technology, etc. An efficient skills management system therefore ought to combine both individual and collective approaches in order to anticipate organizations that promote the development of collective and/or distributed skills, and training situations that promote their construction and transmission.L’objectif de cet article est de discuter de la prise en compte des compétences collectives et distribuées dans un dispositif de gestion des compétences en associant des approches sociologiques et ergonomiques du travail. Le travail collectif dans l’entreprise est aujourd’hui paradoxal : valorisé dans l’organisation par des formes variées de coopérations et contraint et fragilisé dans sa constitution et pérennité face à de nouvelles formes d’emploi. Cependant, les résultats de cette étude, réalisée dans une grande entreprise industrielle et commerciale d’un secteur à risques, montrent qu’un dispositif de gestion de compétences ne peut être « unique ». Il doit se décliner selon des contextes, des spécialités, des évolutions de populations, des évolutions technologiques, etc. Une articulation des points de vue individuel et collectif est nécessaire pour une gestion des

Quelle prise en compte des compétences collectives et distribuées dans la gestion des compétences professionnelles ? How should collective and distributed skills be considered in professional skills management? Cómo tomar en cuenta las competencias colectivas y distribuidas en la gestión de las competencias profesionales ?

Directory of Open Access Journals (Sweden)

Catherine Delgoulet

2008-05-01

Full Text Available L’objectif de cet article est de discuter de la prise en compte des compétences collectives et distribuées dans un dispositif de gestion des compétences en associant des approches sociologiques et ergonomiques du travail. Le travail collectif dans l’entreprise est aujourd’hui paradoxal : valorisé dans l’organisation par des formes variées de coopérations et contraint et fragilisé dans sa constitution et pérennité face à de nouvelles formes d’emploi. Cependant, les résultats de cette étude, réalisée dans une grande entreprise industrielle et commerciale d’un secteur à risques, montrent qu’un dispositif de gestion de compétences ne peut être « unique ». Il doit se décliner selon des contextes, des spécialités, des évolutions de populations, des évolutions technologiques, etc. Une articulation des points de vue individuel et collectif est nécessaire pour une gestion des compétences qui permette de prévoir : des organisations propices au développement des compétences distribuées ou collectives, des situations de formation favorisant leur construction et leur transmission.The purpose of this paper is to discuss how collective and distributed skills are considered in a professional competence management system by associating sociological and ergonomic work approaches. Collective work in companies is currently paradoxical: on the one hand, its value is increased through various forms of cooperation, and on the other hand, it is restricted in its makeup and sustainability by new kinds of employment. However, the results of our study, carried out in a large industrial and retailing company in a high-risk sector, highlight that a “single” and individual professional competence management system is a partial system. Work contexts should take into account technical specialties, changes in populations, changes in technology, etc. An efficient skills management system therefore ought to combine both

PC Technician Street Smarts, Updated for the 2009 Exam A Real World Guide to CompTIA A+ Skills

CERN Document Server

Pyles, James

2009-01-01

An inside look into the life of a PC technician-from everyday tasks to the challenging roadblocks Gaining hands-on experience is considered the most difficult part of trying to break into the PC technician. Building on the standards set by CompTIA-and endorsed by the IT industry worldwide-this book takes you one step further than what you might simply learn in a classroom and shows you how to actually perform the various tasks you can expect to encounter on the job. The Street Smarts series is designed to help current or aspiring IT professionals put their certification to work for them. Full

Fabricação de compósitos com matriz de alumina reforçada com whiskers de mulita

OpenAIRE

Salles, Mário César Fernandez de

2008-01-01

Neste trabalho foram fabricados compósitos cerâmicos utilizando alumina como matriz e whiskers de mulita como reforço. As composições de whiskers foram 10, 20, 30 e 40% em peso. Os whiskers de mulita utilizados como matérias-primas foram obtidos através do tratamento térmico do mineral topázio incolor no Laboratório de Tratamento Térmico de Materiais do ICEB/UFOP. A alumina de elevada pureza foi fornecida pela empresa Alfa Apesar. As matérias primas, após serem pesadas, foram submetidas a um ...

Les compétences infirmières forensiques en milieu carcéral face aux patients atteints de troubles mentaux: une revue de littérature étoffée

OpenAIRE

Davet, Eloïse; Friedli, Karen; Machuret, Bastien; Reyff, Marie de

2015-01-01

Le but de cette revue de littérature étoffée est de mettre en évidence les compétences des infirmières forensiques travaillant, en milieu carcéral, avec des patients atteints de troubles mentaux.

Compósitos de borracha natural ou policloropreno e celulose II: influência do tamanho de partícula Natural rubber or chloroprene rubber and cellulose II composites: influence of particle size

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Bruno de A. Napolitano

2004-01-01

Full Text Available O objetivo deste trabalho foi o desenvolvimento de compósitos claros com propriedades de interesse tecnológico utilizando elastômeros com diferentes polaridades. Para que este objetivo fosse atingido, celulose II em pó foi usada como carga, em borracha natural (NR ou policloropreno (CR. A celulose II foi obtida por coagulação da solução de xantato de celulose em meio ácido, sob agitação constante e à temperatura ambiente, constituindo uma nova forma de obtenção deste tipo de carga. Compósitos com 10 phr de celulose II com NR e CR, respectivamente, foram desenvolvidos tendo como variável o tamanho de partícula da carga. As propriedades mecânicas e os aspectos microscópicos dos diferentes compósitos foram avaliados e comparados com aqueles das formulações sem carga. Os resultados permitiram identificar o compósito como o de melhor resultado, influenciado pela polaridade da matriz elastomérica e pelo tamanho de partícula da carga, conseqüência das condições de moagem usadas.The aim of this work was to develop light composites with properties of technological interest by using elastomers of different polarities. This was achieved by employing cellulose II, in the powder form, as filler in natural rubber (NR and chloroprene (CR. Cellulose II was obtained by coagulation of cellulose xanthate solution, in acid medium, under stirring and at room temperature, which represents, to our knowledge, a new way of obtaining this type of filler. Composites with 10phr of cellulose II and NR or CR were prepared having the particle size as variable. The mechanical properties and the microscopic aspect of the different composites were evaluated and compared with compounds without filler. The results indicated best results for the CR composite, influenced by the polarity of the elastomeric matrix and by the particle size, as a consequence of the milling conditions of the filler used.

Structure Identification Using the US EPA's CompTox Chemistry Dashboard (CompTox CoP)

Science.gov (United States)

Community of practice webinar presentation on the Identification of unknowns in non-targeted analyses (NTA) requires the integration of complementary data types to generate a confident consensus structure.

Compósitos biodegradáveis de polihidroxibutirato (PHB reforçado com farinha de madeira: propriedades e degradação

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José Claudio Caraschi

2002-04-01

Full Text Available O objetivo deste trabalho foi preparar e avaliar compósitos poliméricos mais compatíveis com o ambiente, ou seja, a obtenção de materiais que sejam biodegradáveis e que apresentem uma maior velocidade de degradação no ambiente. Os compósitos foram preparados a partir do plástico biodegradável polihidroxibutirato (PHB com e sem reforço de farinha de madeira, um resíduo agroindustrial, nas proporções de 10% a 40% em massa, pelo processo de extrusão e moldagem por injeção. As amostras foram avaliadas quanto à estabilidade dimensional, à absorção de água, à resistência química e à degradação natural em cinco diferentes situações ambientais, por diversos períodos de tempo. Os resultados obtidos indicaram que todas as amostras sofreram degradações evidenciadas pela perda de massa e pela descoloração em todas as situações avaliadas, e que a utilização de farinha de madeira resultou em materiais com menor resistência química e maiores taxa de absorção de umidade e velocidade de degradação no ambiente.

Análise de ensaios in vitro do compósito de 50% HA-50% TiO2 fabricados pelo método da esponja polimérica

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A. G. S. Galdino

2014-12-01

Full Text Available À medida que há uma melhoria na tecnologia aplicada à saúde humana, a expectativa de vida vem aumentando, mas nem todas as partes do corpo podem manter suas funções com o processo de envelhecimento. A engenharia tecidual foi desenvolvida para substituir, reparar ou reconstruir tecidos ou órgãos perdidos ou danificados por acidentes ou doenças graves através da utilização e desenvolvimento de novos materiais, que sejam biocompatíveis, bioabsorvíveis, porosos, entre outras características. O objetivo deste trabalho é avaliar através dos ensaios in vitro o compósito poroso de hidroxiapatita - titânia (HA-TiO2, com composição de 50% HA - 50% TiO2 para obter arcabouços utilizados para engenharia tecidual óssea. Os corpos de prova foram produzidos pelo método da esponja polimérica, utilizando bicarbonato de sódio como ligante e floculante. A sinterização foi realizada em três temperaturas: a 1250 ºC; 1300 ºC e 1350 ºC. Linhagens imortalizadas de fibroblastos e osteoblastos foram utilizadas para avaliar o compósito frente à citotoxicidade, crescimento e adesão celular. Nesses ensaios foram utilizados três corpos de prova porosos em um intervalo de cinco dias. Os resultados obtidos mostraram-se satisfatórios, com adesão e crescimento das células de fibroblastos e osteoblastos, o que serve como indicador para que esse compósito seja submetido posteriormente a ensaios in vivo.

Predição do comportamento térmico de tubos compósitos através de redes neurais Prediction of thermal behavior of composite tubes using neural networks

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Sheila Contant

2004-12-01

Full Text Available Compósitos poliméricos (plásticos reforçados são materiais formados a partir de um reforço (fase descontínua, normalmente uma fibra e uma matriz polimérica. Esse tipo de material apresenta várias vantagens em relação aos materiais convencionais de engenharia. Entre os métodos de fabricação de compósitos poliméricos está o filament winding (filamento contínuo ou enrolamento filamentar, um processo empregado na fabricação de sólidos de revolução, como tubos e tanques. Neste trabalho, redes neurais artificiais, uma ferramenta computacional inspirada no funcionamento do cérebro humano, foram aplicadas ao processo de filament winding para predição do comportamento térmico de tubos compósitos durante a etapa de cura. Informações sobre o comportamento térmico das peças compósitas podem auxiliar na seleção do ciclo de cura, que é um dos desafios na obtenção de peças de qualidade e a um baixo custo. As redes neurais foram treinadas com dados obtidos através do modelo Lee-Springer. A metodologia foi validada com resultados experimentais da literatura.Polymeric composites or reinforced plastics are materials made with a polymer matrix and a reinforcement. These materials have many advantages when compared to conventional engineering materials. Among the manufacturing methods for composite parts from continuous fiber reinforcement is the filament winding, often used to fabricate closed-surface structures such as tubes and tanks. In this work artificial neural networks, a computational tool inspired in the human brain, were applied in the filament winding process to predict the thermal behavior of composite tubes during the curing step. Information about the thermal behavior of composite parts may help in the selection of the appropriate cure cycle, which is one of the challenges in obtaining quality parts at low cost. Networks were trained with data obtained with the Lee-Springer model. The methodology was validated

Influência da espessura nas propriedades mecânicas de compósitos híbridos interlaminares de curauá/vidro/poliéster

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Clarissa C. Angrizani

2014-01-01

Full Text Available O interesse do uso de fibras vegetais (ex. juta, sisal e curauá para aplicações mais nobres, como em reforço de materiais compósitos poliméricos, vem aumentando com o passar dos anos devido a aspectos diversos e, em especial, à legislação ambiental e à conscientização sobre o ciclo de vida dos produtos. Diante deste contexto, o objetivo deste trabalho é obter materiais compósitos híbridos interlaminares curauá/vidro/poliéster insaturado por moldagem por compressão à quente e analisar a dependência das suas propriedades mecânicas com a espessura. A resistência short beam da amostra mais espessa diminuiu devido ao seu maior teor de vazios. Além disso, a amostra mais delgada apresentou menor dureza, e resistência ao impacto, à tração e ao cisalhamento Iosipescu, atribuído em parte a sua menor fração volumétrica de fibras. De modo geral, o laminado considerado mais adequado foi aquele formado por oito camadas, sendo quatro de fibra de vidro e quatro de curauá, desde que esforços fletores não sejam críticos.

Feixes de fibras Lignocelulósicas refinadas mecanicamente em compósitos cimentícios para avaliação da resistência à tração

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Flávio Airton knuth

2017-07-01

Full Text Available As fibras vegetais têm características particulares em relação a outros tipos de fibras usadas em compósitos. Os estudos utilizam, em sua maioria, fibras cuja lignina fora previamente removida pelo processo de polpação. Segundo a literatura, a lignina prejudica a ancoragem fibra-matriz. No entanto, sem a lignina, é necessário que seja feito tratamento superficial no conjunto fibroso. Isso por que as fibras sofrem processo de inchamento e retração no interior da matriz devido a seu caráter hidrofílico, o que diminui sua vida útil. No entanto, a despeito das considerações literárias, esse trabalho se propõe a fazer uso da vantagem de proteção, estruturação e impermeabilização que a lignina exerce sobre as fibras vegetais. Isso implica na necessidade de suprir a redução da resistência do compósito, especialmente à tração, que a lignina causa pela sua atuação negativa na ancoragem fibra-matriz. Para tanto, fibras lignocelulósicas extraídas de talos de banana foram submetidas a processo de refinamento mecânico. Segundo a literatura, a fibra sofre modificações na sua parede externa quando submetida a esse refinamento. Ao final do processo, foram obtidas fibras com formato helicoidal e superfície corrugada o que resultou em maior aderência no conjunto fibra-matriz. As fibras submetidas ao maior grau de refinamento aumentaram a resistência do compósito à tração na compressão diametral em 40% em relação a corpo de prova de cimento puro.

Sinterização ultrarrápida por micro-ondas de compósitos particulados PZT/FCO preparados por mistura em ultrassom

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C. P. Fernandez

Full Text Available Resumo Pós de Pb(Zr0,53Ti0,47O3 (PZT e Fe2CoO4 (FCO, foram sintetizados separadamente pelo método Pechini e misturados em ultrassom, nas proporções molares 80/20 e 50/50 (PZT/FCO. Os compósitos preparados foram prensados e submetidos à sinterização em forno convencional e sinterização ultrarrápida assistida por micro-ondas. A caracterização estrutural e microestrutural das amostras foram realizadas por difração de raios X e microscopia eletrônica de varredura, respectivamente. Medidas de constante dielétrica em função da temperatura, resistividade elétrica e coeficiente de acoplamento magnetoelétrico foram também realizadas. Os resultados evidenciaram que o método de mistura do PZT com a FCO por ultrassom foi rápido e eficiente, gerando, após sinterização, compósitos particulados com conectividade global (0-3 e distribuição uniforme de grãos da fase ferromagnética (FCO na matriz ferroelétrica (PZT. Da análise estrutural, verificou-se que a sinterização por micro-ondas propiciou um arranjo diferenciado no esquema de conectividade local na amostra (1-3 e (2-3, relacionada com a intensificação dos processos de difusão que ocorrem nesse tipo de sinterização principalmente em sistemas nanométricos. Pelos altos valores de resistividade obtidos, comprovou-se que a integridade das fases foi conservada nos dois métodos de sinterização, sendo mais eficiente na sinterização por micro-ondas, característica que garantiu o comportamento magnetoelétrico em todos os compósitos estudados neste trabalho. Os valores do campo Hmax foram dependentes da concentração da fase ferrita e da sinterização; para a composição 80/20 de 1,4 e 1,9 kOe, e para 50/50 de 3,5 e 3,0 kOe nas amostras sinterizadas por micro-ondas e convencionalmente, compatíveis com a literatura e que confirmaram a integridade das fases constituintes PZT e FCO.

A3byComp: A Support tool for Basic Implementation of Competency Management Systems in Social Entities

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Daniel CLAVERO HERRERO

2015-12-01

Full Text Available The importance of managing processes related to people working in institutions within the scope of FEAPS evidenced by the increasing incorporation into the strategy of the organizations policies aimed at improving the working conditions of workers and in the development of competence management systems aimed at promoting professional development, which aims greater effectiveness and efficiency in providing support for improving the quality of life of people with disabilities and their families. At the same time, banks have highlighted the need for specific instruments and tools that facilitate the implementation of these systems. In Extremadura, it has been developed a software tool for the implementation of basic competence management systems called A3byComp that has been freely available to the entire network promoting industry collaboration aimed mutual learning.

L’usage des contes francophones pour le développement des compétences langagières

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Nataša Žugelj

2015-12-01

Full Text Available Les contes traditionnels sont un genre littéraire qui constitue un excellent support authentique pour le travail sur la langue dans une classe de FLE. S’ils sont accompagnés d’activités variées et ludiques, la découverte ou le perfectionnement d’une langue étrangère peut se faire d’une manière plaisante avec des apprenants de tous âges. En effet, ils se prêtent bien au développement des compétences langagières et sont un excellent terrain d’observations linguistiques, d’enrichissement lexical. De plus, par leur relative brièveté et par un contenu universellement connu, ils proposent un cadre rassurant pour l’exploitation pédagogique.    

Consumer skills contribute to maintaining and diffusing heritage food products Les compétences des consommateurs contribuent au maintien et à la diffusion d’aliments patrimoniaux

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Didier Chabrol

2011-05-01

Full Text Available Our food heritage is not only limited to food products and production techniques, it also includes the consumption skills and technologies (CST used to obtain what the consumer requires from a food product. In a specific food culture, a given food product is linked to specific CSTs. In this paper, we examine this aspect of food heritage through the examples of raw ham in Italy, France and Spain, rice varieties and chocolate. We then discuss two types of conjunction / disjunction between food products and food CSTs: controlled diffusion and diffusion through education. We conclude that the sustainability of localized, “origin” or “terroir” products depends on the existence of skilled consumers. The transmission and diffusion of these skills and technologies are thus factors in the permanence and diffusion of the product itself.Le patrimoine alimentaire n’est pas constitué exclusivement de produits et de techniques de production, mais aussi de compétences et techniques de consommation (CTC utilisées par les consommateurs pour obtenir d’un produit alimentaire l’utilité ou le service qu’ils en attendent. Dans une culture alimentaire donnée, un produit alimentaire spécifique est lié à des CTC spécifiques. Cette dimension du patrimoine alimentaire est examinée à travers les exemples du jambon cru en Italie, en Espagne et en France, de différents riz, et du chocolat. Nous discutons ensuite deux types de cohérences / incohérences entre produits et CTC : contrôle par la source, diffusion par l’éducation. Nous concluons que la durabilité de produits locaux, d’origine ou de terroir dépend de l’existence de consommateurs compétents. La transmission et la diffusion des compétences et techniques de consommation sont donc des facteurs de la pérennité et de la diffusion du produit lui-même.

Un test de classement en ligne pour évaluer les niveaux de compétence et constituer des groupes classes

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Patricia Kohler

2012-01-01

Full Text Available L’Université de Fribourg a développé un test de classement en ligne avec la plateforme Moodle pour évaluer les compétences des étudiants en langues étrangères (compréhension orale, compréhension écrite et production écrite selon le Cadre européen commun de référence du Conseil de l’Europe. Une démarche qualité nous a aidé à réfléchir sur les modèles de tests de classement en ligne de sorte que nos résultats soient transférables à d’autres contextes que l’enseignement des langues étrangères. Nous avons évalué l’acceptabilité de notre test avec, d’une part, les données quantitatives produites par Moodle lorsque les étudiants passent le test. D’autre part, nous avons analysé les entretiens d’étudiants décrivant leur expérience avec le test. Certains résultats montrent la pertinence du modèle de test : la durée des sous-tests, l’utilité d’une auto-évaluation et la nécessité de sous-tests sur chaque compétence. D’autres résultats se dégagent sur la représentation qu’a l’usager d’un test en ligne qui remet en question des rapports fondamentaux de l’individu au temps, à l’espace, à l’identité et à ses sensibilités d’ordre culturel.

Influência de estabilizantes na degradação foto-oxidativa de filmes de compósitos de SWy-1/poli(óxido de etileno

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Patrícia Coelho Lombardo

2015-02-01

Full Text Available Compósitos de poli(óxido de etileno (PEO com argila montmorilonita SWy-1 e estabilizantes (2-hidroxibenzofenona e tinuvin 770 foram preparados pelo método de intercalação em solução. Os filmes obtidos foram expostos a irradiação UV, e os produtos da fotodegradação foram monitorados por FTIR (Fourier Transform Infrared Spectroscopy, ou Espectroscopia no infravermelho por transformada de Fourier e SEC (Size Exclusion Chromatography, ou cromatografia de exclusão por tamanho. O PEO puro apresentou maior coeficiente de degradação, kd, comparado com as demais amostras. O sistema que apresentou o menor valor para o coeficiente de degradação (kd = 1,9×10–6 mol g–1 h-1 foi o compósito de PEO/5%SWy-1 com 0,25% de tinuvin 770. Nesse caso, a estabilização da matriz de PEO pode ser atribuída à argila juntamente com o tinuvin 770. A argila dispersa e absorve a irradiação UV, e o tinuvin age como estabilizante do tipo HALS (do inglês hindered amine light stabilizer, ou estabilizantes à luz tipo aminas impedidas.

Compósitos à base de cimento reforçados com polpa celulósica de bambu. Parte I: Determinação do teor de reforço ótimo Cement-based composite reinforced with bamboo pulp. Part I: Determination of optimum reinforcement percentage

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Marcos A. S. dos Anjos

2003-08-01

Full Text Available Este trabalho apresenta os resultados experimentais de um estudo em que se procurou desenvolver compósitos de matriz cimentícia reforçada com polpa de bambu. Foram usados dois tipos de polpa: refinada e sem refino. Fez-se variar o teor de fibras de 0 a 16% em massa de cimento e se desenvolveu um processo com sucção, moldagem e prensagem para fabricação dos compósitos. As relações constitutivas dos compósitos foram definidas através de ensaio a compressão e tração de corpos-de-prova cilíndricos de 5x10 cm e do ensaio de flexão em três pontos. A partir delas, foi obtida a capacidade de absorção de energia. Determinaram-se, também, algumas propriedades físicas, como absorção, porosidade aparente, densidade seca e úmida dos compósitos. Os resultados mostraram melhor performance dos compósitos com fibras refinadas em relação àquelas com fibras sem refino e também indicaram que o teor ótimo de fibras refinadas se situou em torno de 8%, quando promoveram notáveis melhoramentos das propriedades mecânicas dos compósitos em relação à matriz plena.This work presents the experimental results of a study which intended to develop a composite with cementations matrix reinforced with bamboo pulp. Two types of pulps were used: refined and unrefined pulps. The fibre content varied between 0 and 16% cement (weight basis. After the preparation of fresh composite mix the experimental specimens were prepared applying a specially developed process based on Hastshek method using suction then moulding and pressing. The compression, tension and the flexural behavior and their constitutive relations were established using 5 cm diameter by 10 cm high cylindrical specimens and three point bending tests at respectively. The energy absorbing capacity of the new composites was also established. Physical properties such as water absorption, apparent porosity, dry and humid density were also obtained. The results showed a better performance

Avaliação da biodegradação de compósitos de poli(ε-caprolactona/fibra de coco verde Evaluation of biodegradation poly(ε-caprolactone/green coconut fiber

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Marcia C. A. M. Leite

2010-01-01

Full Text Available Uma classe de plásticos com destaque crescente são os polímeros biodegradáveis, como a Poli(ε-caprolactona (PCL. Quando esses polímeros são utilizados para elaboração de compósitos com fibras naturais, novas propriedades são agregadas. Existem vários métodos de modificação química da fibra para melhorar a adesão dessas fibras em matrizes poliméricas. Neste trabalho foi estudada a biodegradabilidade em solo simulado de compósitos de PCL/fibra de coco (antes e após a modificação química da fibra por reação de acetilação com avaliação da perda de massa e da modificação da morfologia. A espectroscopia na região do infravermelho mostrou a eficiência da reação de acetilação nas fibras. Os compósitos enterrados em solo simulado apresentaram perda de massa e a degradação das amostras foi confirmada pela modificação da morfologia observada através de análises como as Microscopias Óptica e Eletrônica de Varredura. O comportamento térmico dos compósitos, analisado por Calorimetria Diferencial de Varredura mostrou diferença no teor de cristalinidade da matriz com a incorporação da fibra.Biodegradable polymers such as poly (ε-caprolactone (PCL have received increasing attention. New properties are achieved when these polymers are used in composites with natural fibers. Several methods exist for the chemical modification of the fiber to improve adhesion to the polymer matrices. This work deals with the biodegradation in simulated soil of PCL/coconut fiber composites (before and after fiber chemical modification by acetylation - reaction with the evaluation of mass loss and morphology. Infrared spectroscopy has shown the efficiency of fiber acetylation. The composites buried in simulated soil presented weight loss. The degradation of the samples was confirmed by the morphology modification observed by Scanning Electron Microscopy and Optical Microscopy analysis. The thermal properties analyzed with

Efeitos do tipo de poliestireno de alto impacto nas propriedades de compósitos termoplásticos com farinha de resíduo de madeira The effects of the high impact polystyrene morphology on the properties of wood-plastic composites

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Wladimir L. Vianna

2004-12-01

Full Text Available A tecnologia dos chamados Compósitos Termoplásticos com Madeira envolve conceitos de compatibilidade e processabilidade e apresenta grandes desafios tecnológicos para a formulação e estabilização da mistura. Devido à baixa estabilidade térmica da celulose, a grande maioria das resinas termoplásticas utilizadas na preparação desses compósitos está restrita às resinas poliolefinicas, estirênicas e ao poli(cloreto de vinila. O Poliestireno de Alto Impacto (HIPS é um termoplástico bifásico de grande versatilidade de propriedades decorrentes das variações de composição e morfologia das partículas de borracha dispersas na matriz estirênica. Além da sua temperatura relativamente baixa de processamento, estas características tornam o HIPS um termoplástico de grande interesse para aplicações em compósitos com farinha de resíduo de madeira, uma vez que a otimização do balanço de propriedades de rigidez e impacto pode ser alcançada através do controle da morfologia e da formulação do compósito. No presente estudo, "tipos" comerciais de HIPS com diferenças no índice de fluidez e na distribuição do tamanho de partículas foram utilizados na preparação de compósitos termoplásticos com farinha de resíduo de madeira. As propriedades mecânicas dos compósitos obtidos foram discutidas em termos das características morfológicas dos HIPS utilizados e da quantidade de farinha de resíduo de madeira no compósito. Pela simples aplicação da regra das misturas, mostrou-se que devido à baixa densidade do resíduo de madeira, o reforço celulósico poderia ser utilizado eficientemente na substituição de cargas minerais ou fibra de vidro em compósitos termoplásticos com um melhor desempenho em termos de resistência e rigidez específica. A microscopia eletrônica de varredura foi utilizada na análise de superfícies de fratura para ilustrar a dispersão da farinha de madeira na matriz estirênica, a

Efeito de impactos repetidos de baixa energia em compósitos pultrudados

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Morais Willy Ank de

2001-01-01

Full Text Available Danos internos podem ser gerados em compósitos de matriz polimérica submetidos a impactos de baixa energia. O efeito repetido de eventos desse tipo pode levar, eventualmente, à falha da estrutura. Neste trabalho dois tipos de perfis pultrudados foram submetidos a impactos por queda livre de peso de 0,5 m e 1,0 m de altura. Os resultados obtidos foram analisados em função da disposição das fibras nos perfis e mostram que a existência de uma camada rica em resina em um dos perfis, contribui para reduzir significativamente o desempenho deste perfil. Este comportamento foi associado à formação prematura de trincas na camada rica em resina. O número de eventos de impacto, o tempo de duração de cada choque e a forma da área danificada foram correlacionados com a presença, ou não, da região rica em resina. Os resultados obtidos indicam ainda que a diferença na microestrutura dos perfis analisados é mais significativa para os ensaios de menor energia (queda de 0,5 m. Para os ensaios de maior energia (queda de 1 m a configuração do material teve apenas uma importância secundária.

Caracterização mecânica e térmica de compósitos de poli (cloreto de vinila reforçados com fibras de sisal Mechanical and thermal characterization of the polyvinyl chloride-sisal fibers composites

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Gilson S. Martins

2004-12-01

Full Text Available Compósitos de PVC, plastificados com diferentes sistemas de plastificação e reforçados com fibras de sisal, foram processados em moinho de dois rolos. A influência do tipo e teor do plastificante, do comprimento e do teor das fibras nas propriedades dos compósitos obtidos foi estudada. Dois tipos de plastificantes foram usados, um líquido (do tipo poliéster e um sólido permanente (copolímero etileno/ acetato de vinila/ monóxido de carbono. As fibras usadas foram previamente lavadas com água a 80 °C por uma hora. Os compósitos, com fibras curtas aleatoriamente distribuídas, foram caracterizados através de ensaio mecânico de resistência à tração, microscopia eletrônica de varredura (MEV, e análises térmicas de calorimetria exploratória diferencial (DSC e análise por termogravimetria (TG. O comprimento ótimo de fibra obtido para os compósitos foi de 6 mm. O uso do plastificante sólido mostrou-se viável e promoveu uma maior molhabilidade da fibra pela matriz nos compósitos, principalmente para teores acima de 40 pcr. As análises térmicas mostraram que a substituição do plastificante líquido pelo plastificante sólido não afetou a estabilidade térmica das matrizes e dos compósitos.Composites consisting of flexible polyvinyl chloride (PVC, plasticized with two different types of plasticizers and reinforced with sisal fibers, were processed on a two-roll mixing mill. Two plasticizers were used, a liquid plasticizer (polyester and a permanent solid plasticizer (ethylene/ vinyl acetate/ carbon monoxide copolymer - Elvaloy® , to form two kinds of polymeric matrices. For each one of these matrices, the influence of plasticizers type, plasticizers content, size and quantity of sisal fibers in the composite properties has been studied. The fibers were washed with water at 80 °C during one hour. The composites with randomly distributed short fibers were characterized by mechanical analysis, scanning electron microscopy

Efeito da modificação de superfície de fibras nas propriedades mecânicas de compósitos a base de poli (tereftalato de butileno reforçado por fibras naturais inorgânicas

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Felipe Darabas Rzatki

2014-06-01

Full Text Available O presente trabalho visa investigar a viabilidade de utilização de fibras naturais de sílica amorfa (FNSA como agente de reforço em polímeros de engenharia, assim como avaliar o seu potencial como alternativa às fibras de vidro curtas em aplicações industriais. Diferentes modificações na química de superfície dessas fibras foram avaliadas buscando melhorar a adesão na interface entre fibras e matriz, e consequentemente, melhorar as propriedades mecânicas do compósito. As modificações superficiais das FNSA foram realizadas através de agentes de acoplamento do tipo silano, providos com funções orgânicas distintas. O PBT foi selecionado como matriz devido a sua conhecida facilidade de processamento, mesmo após a incorporação de grandes quantidades de aditivos. A modificação das FNSA foi avaliada a partir da análise termogravimétrica acoplada à espectroscopia no infravermelho com transformada de Fourier. A resistência mecânica e fratura dos compósitos foi investigada por ensaios de tração e microscopia eletrônica de varredura. Finalmente, obtiveram-se compósitos com fibras modificadas com resistência à tração 40% superior ao material base puro.

Comportamento da viscosidade de um compósito vidro-partícula de alumina Viscosity behaviour of a glass-alumina particle composite

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J. A. Rodrigues

2003-04-01

Full Text Available O aumento na produção de concretos refratários de alto desempenho tem demandado proporcional acréscimo no entendimento do comportamento reológico de suspensões concentradas de sólidos. Os concretos podem ser considerados como sistemas contendo agregados cujo diâmetro médio de partícula é superior a 100 mm e partículas finas que constituem a matriz. A reologia desse sistema é determinada, predominantemente, pela viscosidade da matriz, porém influenciada por parâmetros associados aos agregados. Este trabalho simula um sistema fluido-partícula, empregando um compósito vidro-partícula de alumina, caracterizando-o quanto à sua viscosidade em temperaturas em torno de 600 °C. Um viscosímetro de flexão foi empregado para medir as altas viscosidades do compósito. São mostrados resultados de viscosidade para diferentes teores de partículas de alumina. O sistema vidro-partícula apresentou um máximo na viscosidade para teores em torno de 50%-vol de partículas. Até aproximadamente 40%-vol de partículas, o compósito se comporta como um sistema newtoniano entre 560 ºC e 670 °C. Os resultados deste trabalho indicam a possibilidade de simulação da reologia na preparação de concretos refratários e da fluência do concreto operando em alta temperatura.Basic knowledge on rheological behaviour of highly concentrated suspensions is nowadays a very important issue in the refractory industry, regarding the production of high-performance castables. Refractory castables can be considered as a system containing aggregates and particles larger than 100 mm and finer ones constituting a matrix. In that system, the rheological behaviour is mainly determined by the viscosity of the matrix, although it is affected by parameters related to the aggregates. This work simulates a fluid-particle system through the use of a glass-alumina particle composite which viscosity was evaluated at temperatures close to 600 ºC. A beam-bending viscometer

Leader mode d'emploi 10 compétences essentielles pour communiquer, collaborer et innover

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Paquet, René

2013-01-01

Communiquer efficacement, favoriser la collaboration, stimuler la créativité et résoudre les conflits dans un climat de coopération, voilà les aptitudes qui caractérisent le leader qui dirige avec brio. Que vous soyez à la barre d'une équipe de cinq ou de trente personnes, vous trouverez dans cet ouvrage tous les outils pour entretenir la motivation de vos employés, susciter les bonnes réactions, éviter les faux pas, maximiser votre productivité et ainsi devenir un meneur de premier ordre. Quelques conseils à appliquer : Prendre le temps de créer une relation avec chacun de mes collaborateurs. Apprendre les règles, les normes et les valeurs de l'organisation. Favoriser le développement des compétences et l'acquisition des connaissances. Établir des canaux de communication. Exprimer des attentes claires. Quelques erreurs à éviter Faire de la micro-gestion : tenter de tout contrôler. Travailler en vase clos. Remettre à plus tard les tâches moins agréables. Rester dans ma zone de confort ...

Estudo da flamabilidade e resistência à chama de compósito de poliéster insaturado e fibra da folha do abacaxizeiro (PALF)

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Ribeiro, Luciene Mendes

2011-01-01

Na presente pesquisa foram desenvolvidos compósitos com fibras da folha do abacaxizeiro (PALF - Pineapple Leaf Fiber), utilizando resina de poliéster insaturado como matriz, incorporando retardante de chama em diferentes composições. As fibras da folha do abacaxizeiro foram obtidas na ramada 4 do município de Ielmo Marinho no Estado do Rio Grande do Norte. A resina de poliéster insaturado e o catalisador foram comprados no comércio. O retardante de chama de alumina trihidratada (hidróxido de ...

Final Scientific/Technical Report, USDOE Award DE-FG-02ER54684, Recipient: CompX, Project Title: Fokker-Planck/Ray Tracing for Electron Bernstein and Fast Wave Modeling in Support of NSTX

International Nuclear Information System (INIS)

Harvey, R.W.

2009-01-01

This DOE grant supported fusion energy research, a potential long-term solution to the world's energy needs. Magnetic fusion, exemplified by confinement of very hot ionized gases, i.e., plasmas, in donut-shaped tokamak vessels is a leading approach for this energy source. Thus far, a mixture of hydrogen isotopes has produced 10's of megawatts of fusion power for seconds in a tokamak reactor at Princeton Plasma Physics Laboratory in New Jersey. The research grant under consideration, ER54684, uses computer models to aid in understanding and projecting efficacy of heating and current drive sources in the National Spherical Torus Experiment, a tokamak variant, at PPPL. The NSTX experiment explores the physics of very tight aspect ratio, almost spherical tokamaks, aiming at producing steady-state fusion plasmas. The current drive is an integral part of the steady-state concept, maintaining the magnetic geometry in the steady-state tokamak. CompX further developed and applied models for radiofrequency (rf) heating and current drive for applications to NSTX. These models build on a 30 year development of rf ray tracing (the all-frequencies GENRAY code) and higher dimensional Fokker-Planck rf-collisional modeling (the 3D collisional-quasilinear CQL3D code) at CompX. Two mainline current-drive rf modes are proposed for injection into NSTX: (1) electron Bernstein wave (EBW), and (2) high harmonic fast wave (HHFW) modes. Both these current drive systems provide a means for the rf to access the especially high density plasma--termed high beta plasma--compared to the strength of the required magnetic fields. The CompX studies entailed detailed modeling of the EBW to calculate the efficiency of the current drive system, and to determine its range of flexibility for driving current at spatial locations in the plasma cross-section. The ray tracing showed penetration into NSTX bulk plasma, relatively efficient current drive, but a limited ability to produce current over the whole

Effect of resin liners on the microleakage of class V dental composite restorations Efeito do uso de forradores resinosos sobre a microinfiltração de restaurações classe V em compósito odontológico

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Roberta Caroline Bruschi Alonso

2004-03-01

Full Text Available PURPOSE: The aim of this study was to evaluate the effect of an adhesive applied in layers of different thickness or in association with a filled adhesive or with a low viscosity composite liner on the microleakage of composite restorations. METHODS: Forty bovine incisors were prepared with round cavities (4mm diameter X 2mm depth on the cementoenamel junction. The teeth were assigned to four groups according to the liner used: 1 (control - application of 1 layer of the Scotchbond Multi Purpose adhesive system (SBMP; 2 - application of 3 layers of SBMP; 3 - application of 1 layer of SBMP followed by application of one layer of Optibond FL adhesive; 4 - application of one layer of SBMP followed by application of flowable composite Flow-it. All cavities were restored using composite resin Z100. The microleakage test was conducted according to ISO (TR11405. Data were analyzed by Kruskall-Wallis test (a=0.05. RESULTS: Group 4 showed less leakage than Group 1. Groups 2 and 3 showed intermediate values and there were no statistical differences when they were compared to the values of Groups 1 and 4 CONCLUSION: The use of resin liners with flowable composites can reduce the microleakage of composite restorations.OBJETIVO: O objetivo desse estudo foi avaliar os efeitos da aplicação de um adesivo em diferentes espessuras ou em associação com um adesivo com carga ou com compósito de baixa viscosidade na microinfiltração marginal de restaurações com compósito odontológico. MÉTODOS: Quarenta incisivos bovinos foram selecionados e cavidades circulares (4mm de diâmetro X 2mm de profundidade foram preparadas na região da junção cemento-esmalte. Os dentes foram então divididos em quatro grupos de acordo com o forramento utilizado: 1: (controle aplicação do sistema de união Scotchbond Multi Uso (SBMU - 1 camada de adesivo; 2: aplicação de 3 camadas do adesivo SBMU; 3: aplicação do SBMU, seguido pela aplicação de uma camada do adesivo

Compósitos de HDPE com resíduos de fibras têxteis. Parte I: caracterização mecânica HDPE composites with textile fibers waste. Part I: mechanical characterization

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Maira Finkler

2005-07-01

Full Text Available Neste trabalho são apresentados e discutidos os resultados das propriedades mecânicas de novos materiais compósitos preparados com resíduos de fibras têxteis poliméricas e de polímeros commodities. As fibras naturais oferecem vantagens sobre as sintéticas, em termos de propriedades mecânicas e térmicas. Os compósitos foram preparados a partir da mistura de polietileno de alta densidade (HDPE e resíduos de fibras têxteis (50% algodão /50% acrílico em teores crescentes de 10 a 40%, em um misturador de alta velocidade, utilizando Surlyn 2601, Polybond 3009 e Polybond 1009 como agentes compatibilizantes. Corpos-de-prova para ensaios de tração, flexão e impacto foram produzidos a partir de chapas obtidas em uma prensa hidráulica. Os compósitos que utilizaram agentes compatibilizantes apresentaram os melhores resultados de resistência à tração e à flexão, principalmente com 5% do agente Polybond 3009 e 20 a 40% de resíduos de fibras têxteis.In this work, results of mechanical properties of new composites based on textile fiber residues from clothing industry and commodity polymers are discussed. Natural fibers offer some advantages over synthetic ones, regarding mechanical and thermal properties. The composites were produced by mixing high density polyethylene with the textile fibers (50% cotton /50% acrylic in increasing contents, from 10 to 40% in a thermokinetic mixer, using Surlyn 2601, Polybond 3009 and Polybond 1009 as coupling agents. The tensile, flexural and impact samples were produced by cutting sheets obtained in a hydraulic press. The composites with coupling agents showed good results of tensile and flexural strength, mainly with 5% of Polybond 3009 and 20-40% of textile fiber residues.

Formation des formateurs en ligne : obstacles, rôles et compétences

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Louise Sauvé

2004-01-01

Full Text Available L’adoption d’une technologie de l’information et de la communication (TIC pour la formation ne peut se faire sans changement dans l’organisation. Ces changements touchent les formateurs, hommes et femmes, qui ont une histoire professionnelle, une mentalité, des pratiques qui se sont construites au cours des années et dans un contexte précis de travail. Or les changements technologiques peuvent déstabiliser la vie professionnelle des formateurs. Il est donc essentiel de gérer ce changement, car le succès des projets d’introduction des TIC dans la formation n’est plus fonction de la puissance des technologies, mais plutôt de la capacité des formateurs à exploiter leur potentiel afin de changer et d’améliorer l’efficience du processus d’apprentissage. C’est dans un contexte d’implantation d’une formation des formateurs en ligne que se situe cet article qui aborde les questions suivantes : quels sont les obstacles au changement par rapport à l’adoption des TIC dans le milieu de la formation? Quels sont les principaux rôles d’un formateur en ligne (ou e-formateur? Quelles sont les compétences générales que les formateurs doivent développer pour soutenir les apprenants dans un contexte de formation en ligne (synchrone et asynchrone?

Análise da durabilidade de compósitos cimentícios de elevada capacidade de deformação reforçados com fibras

OpenAIRE

Fernanda Bianchi Pereira da Costa

2015-01-01

Apesar do avanço tecnológico crescente na construção civil, a falta de durabilidade das estruturas de concreto, tanto em edificações como pavimentação, tem sido constatada com acentuada assiduidade e proporção. O compósito cimentício de elevada deformação, também conhecido como Engineered Cementitious Composites (ECC), foi difundido a partir do conceito de concretos de alto desempenho reforçado com fibras, visando suprir o comportamento frágil do concreto convencional e problemas relacionados...

Análise modal teórica via método dos elementos finitos de uma viga feita a base de materiais compósitos

OpenAIRE

Faria, Antônio; Silva, Vânia; Carvalho, Jonas; Tita, Volnei

2002-01-01

Com o desenvolvimento tecnológico houve um aumento nos requisitos de projeto que promoveram um conseqüente aumento na necessidade de novos materiais que combinassem propriedades de baixo peso e alta resistência que atendessem a esses requisitos. Dentre estes materiais, destacam-se os materiais compósitos por combinar baixo peso e alta rigidez. Assim procura-se neste artigo, através de análises numéricas, descrever a influência da seqüência de empilhamento das lâminas no comportame...

Osseointegração clínica-radiológica do compósito hidroxiapatita-lignina entre implante metálico e tecido ósseo em coelho Clinical-radiographic osseointegration of hydroxyapatite-lignin composite between metallic implant and bone tissue in rabbit

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M.M. Martinez

2009-08-01

Full Text Available Para avaliar o compósito hidroxiapatita-lignina na osseointegração entre implante metálico e o tecido ósseo, foram utilizados 20 coelhos adultos, nos quais foi realizada uma falha óssea na face lateral proximal de ambas as tíbias. Na tíbia esquerda, introduziu-se, no canal medular, um pino intramedular de Schanz revestido com o compósito em sua parte rosqueada, após o preenchimento daquele com 1000mg do compósito. A falha cortical foi preenchida com o compósito. O mesmo foi feito na tíbia direita, porém sem a utilização do compósito, servindo como controle. A avaliação clínica baseou-se na deiscência, claudicação, sensibilidade dolorosa e circunferência tibial. Foram realizadas radiografias imediatamente após a cirurgia e aos oito, 30, 60, 90 e 120 dias do pós-operatório. A maioria dos animais apresentou evolução clínica normal. Nas radiografias do grupo tratado, houve decréscimo da radiopacidade no defeito e no espaço medular até tornar-se semelhante à do osso circunvizinho, quadro inverso ao do grupo-controle. Conclui-se que o compósito hidroxiapatita-lignina não mostrou indícios clínicos de rejeição e que o tecido visualizado na altura da falha óssea e ao redor do pino intramedular tinha radiopacidade semelhante à do osso circunvizinho, o que sugere que o material promoveu a integração com o tecido ósseo.This study evaluated a sinthetic hydroxyapatite-lignin composite for osseoingration between metallic implant and bone tissue. Twenty New Zealand rabbits were used. A defect was made a the proximal region of lateral surfaces of both tibias. An intramedullary pin was inserted in the medullary cavity of the left tibia after filling the cavity with 1,000mg of the composite and covering the thread part of the pin with the composite. The same procedure was made in control tibias without the composite. Clinical evaluation was based on inflammatory reaction, dehiscence, lameness, pain, and tibial

Propriedades de compósitos híbridos de borracha nitrílica, fibras de sisal e carbonato de cálcio Properties of nitrile rubber, sisal fiber and calcium carbonate hybrid composites

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Marco A. Iozzi

2004-06-01

Full Text Available Neste trabalho, estudou-se a influência do teor de carbonato de cálcio nas propriedades mecânicas e térmicas da borracha nitrílica, e do comprimento das fibras de sisal nas propriedades mecânicas dos compósitos de borracha nitrílica/fibras de sisal, e borracha nitrílica/carbonato de cálcio/fibras de sisal. Os materiais foram caracterizados através de ensaios mecânicos de resistência à tração, microscopia eletrônica de varredura (MEV, e termogravimetria (TG. O melhor desempenho mecânico dos compósitos com as fibras curtas aleatoriamente distribuídas foi obtido para o comprimento das fibras de 6 mm, e teor de carbonato de 67 pcr. A análise térmica mostrou que os compósitos são estáveis até cerca de 300 °C. Os resultados mostraram que os materiais obtidos possuem uma boa relação custo/benefício tornando promissora sua utilização.In this work, nitrile rubber with sisal fibers composites and nitrile rubber with calcium carbonate and sisal fibers composites were developed. The influence from the calcium carbonate amount and size of sisal fibers on the composite properties was studied. The composites, with short fibers randomly distributed, were characterized by mechanical analysis, scanning electron microscopy (SEM, and thermogravimetric analysis (TGA. The optimal size of sisal fibers to reinforce the nitrile matrix was 6 mm. The ideal volume of calcium carbonate was 67 phr. TGA analysis demonstrated that the composites are stable up to 300 °C. The materials developed have a good cost/benefits relation, being therefore promising their utilization.

Preparação e caracterização de materiais compósitos SiC/caulim/Al via "squeeze-casting" Preparation and characterization of SiC/kaolin/Al composite materials by squeeze- casting

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M. Freitas

2009-09-01

Full Text Available Na busca de materiais com propriedades diferenciadas, vem aumentando nos últimos anos as pesquisas em materiais compósitos. Um dos importantes métodos de fabricação destes compósitos é o processo de infiltração sob pressão de metal fundido denominado "squeeze-casting". Este processo oferece algumas vantagens, tais como facilidade de produzir o compósito, baixo custo e capacidade de formação de estruturas em rede. Neste trabalho foram produzidos e caracterizados compósitos SiC-Al, com concentrações em caulim variando entre 10 e 50% em substituição a fase majoritária SiC. As pré-formas cerâmicas foram produzidas controlando-se a fração granulométrica do SiC/caulim para uma melhor infiltração. Estas pré-formas, após sinterização a 1100 ºC/1 h, resultaram altamente porosas, sendo a porosidade aumentada com o aumento do caulim em substituição ao SiC. Análises de DRX mostraram a existência de partículas de quartzo além da fase SiC como constituintes das pré-formas. Durante o processo de infiltração e tratamento térmico, o alumínio no estado líquido reagiu preferencialmente com o quartzo e outros aluminossilicatos da pré-forma reduzindo-os, precipitando alumina e silício na microestrutura, a qual apresentou também alumínio em excesso que não reagiu no processo. A sílica e os silicatos da pré-forma, ao reagirem preferencialmente com o alumínio, evitaram a reação do Al com o SiC, prevenindo a formação da fase Al4C3,, a qual é altamente higroscópica e causa a degradação do compósito. Dependendo da composição, os compósitos SiC-caulim-Al desenvolvidos neste trabalho, podem ser usados em aplicações que envolvam elevada resistência mecânica à flexão (240 a 300 MPa, baixa densidade e dureza superficial entre 180 e 380 kgf/mm².In search of materials with different properties, has been increasing the research on composite materials in recent years. One of the important methods of

Resíduos de sisal como reforço em compósitos de polipropileno virgem e reciclado Virgin and recycled polypropylene composites reinforced with sisal by-product

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Francisco Rosário

2011-01-01

Full Text Available Foram estudadas as propriedades térmicas e mecânicas de compósitos de polipropileno, virgem e reciclado, reforçados com 30% em massa de fibras residuais de sisal, assim como o perfil de processamento e a morfologia da matriz polimérica. Para tanto, foram determinadas a resistência à tração, o módulo de Young, alongamento na ruptura, e energia de impacto. As amostras também foram caracterizadas por MEV, DMTA e TG. Para ambos os compósitos de polipropileno, virgem e reciclado, com a adição das fibras, o alongamento na ruptura mostrou uma queda significativa, enquanto que a resistência à tração não sofreu grandes variações. Houve um aumento significativo nos valores de tração na ruptura e de energia de impacto com a adição das fibras de sisal na matriz de polipropileno. As análises térmicas mostraram ligações secundárias, como as ligações polares, entre as fibras e a matriz, concordando com o comportamento mecânico dos compósitos. Constatou-se que a temperatura de transição vítrea não variou após a adição da fibra.The mechanical and thermal properties of virgin and recycled polypropylene composites reinforced with 30% by mass of residual sisal fibers were studied, in addition to an analysis of the extrusion process and morphology of the polymeric matrix. Tensile strength, Young's modulus, elongation at break, and impact energy were determined. The samples were also characterized by SEM, DMTA and TG analyses. Elongation at break of the composites presented a significant decrease, while the tensile strength was not affected significantly by addition of sisal fibers. A significant increase was observed in the tension of rupture and in the impact energy of the composite reinforced with sisal fiber. The thermal analyses indicated secondary interactions, such as polar interactions, between the fibers and the matrix, consistent with the mechanical behavior of the composites. The glass transition temperature has not

Avaliação da remoção de cromo (III por materiais compósitos porosos adsorventes de PE-g-MA, fibra de coco e quitosana, usando planejamento experimental

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Dilma Alves Costa

2017-04-01

Full Text Available RESUMO Os processos de adsorção podem ser empregados no tratamento de efluentes líquidos contendo metais pesados visando a reduzir os danos ambientais. Porém, o alto custo dos materiais adsorventes justifica a aplicação de adsorventes alternativos, como a fibra de coco (FC e a quitosana (Q. Assim, este trabalho teve como objetivo desenvolver compósitos porosos adsorventes a partir da mistura de polietileno graftizado com anidrido maleico/FC/Q/NaCl, como agente porogênico (PE-g-MA/FC/Q/NaCl, e avaliar estatisticamente a capacidade de adsorção do cromo (III em solução, com auxílio do software Statistica 5.0®. Os resultados mostraram que a eficiência do processo sofreu influência das dimensões da FC, do teor de Q e do pH da solução contendo Cr (III. A capacidade máxima de remoção de Cr (III por unidade de massa do compósito foi de 42,28 mg.g-1.

L’ingénierie pédagogique à base d’objets et le référencement par les compétences

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Gilbert Paquette

2004-01-01

Full Text Available Nous situons l’ingénierie pédagogique au confluent du design pédagogique, du génie logiciel et de l’ingénierie cognitive. Puis, dans l’optique d’une ingénierie pédagogique à base d’objets, nous proposons une méthode permettant de représenter graphiquement les connaissances et les compétences, puis de les associer aux ressources d’apprentissage. Par la suite, nous montrons comment cette méthode peut contribuer à améliorer la qualité des environnements en ligne à chacune des phases de leur cycle de vie.

An unusual form of spondyloepiphyseal dysplasia, with advanced carpal and spinal end-plate ossification mimicking COMP-mutation-like multiple epiphyseal dysplasia

Energy Technology Data Exchange (ETDEWEB)

Pazzaglia, Ugo E.; Zarattini, Guido [University of Brescia Medical School, Department of Orthopaedics and Traumatology, Brescia (Italy); Beluffi, Giampiero [Fondazione IRCCS Policlinico S. Matteo, Section of Paediatric Radiology, Department of Radiodiagnosis, Pavia (Italy)

2008-07-15

We present a child with irregular ossification of tubular bone epiphyses, short bones, and spine. The radiographic evolution of bones undergoing endochondral ossification was followed from the age of 1 year 9 months to 6 years. The unusual features demonstrated in this child made classification difficult: pseudoachondroplasia was excluded because no mutations of the COMP gene were found. Considering the evolution of the radiographic appearances, the most likely diagnosis would seem to be an unusual form of spondyloepiphyseal dysplasia, mimicking some aspects of multiple epiphyseal dysplasia. Endochondral ossification was diffusely altered with a mixture of epiphyseal ossification delay associated with acceleration and early fusion. This case was a unique presentation within the family, suggesting a mutation in the affected child. (orig.)

An unusual form of spondyloepiphyseal dysplasia, with advanced carpal and spinal end-plate ossification mimicking COMP-mutation-like multiple epiphyseal dysplasia

International Nuclear Information System (INIS)

Pazzaglia, Ugo E.; Zarattini, Guido; Beluffi, Giampiero

2008-01-01

We present a child with irregular ossification of tubular bone epiphyses, short bones, and spine. The radiographic evolution of bones undergoing endochondral ossification was followed from the age of 1 year 9 months to 6 years. The unusual features demonstrated in this child made classification difficult: pseudoachondroplasia was excluded because no mutations of the COMP gene were found. Considering the evolution of the radiographic appearances, the most likely diagnosis would seem to be an unusual form of spondyloepiphyseal dysplasia, mimicking some aspects of multiple epiphyseal dysplasia. Endochondral ossification was diffusely altered with a mixture of epiphyseal ossification delay associated with acceleration and early fusion. This case was a unique presentation within the family, suggesting a mutation in the affected child. (orig.)

Síntese e caracterização de compósito magnético nanoestruturado contendo óxido de manganês para remoção de íons Cd(II do meio aquoso

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A. P. Heitmann

2014-09-01

Full Text Available O tratamento de efluentes contendo cádmio é de grande interesse devido à persistência desse contaminante no meio ambiente e às graves doenças que pode causar ao homem. No presente trabalho, foi utilizado o compósito magnético Mn3O4/Fe3O4 como adsorvente do íon cádmio (II em meio aquoso. O material adsorvente foi sintetizado e caracterizado segundo as técnicas de difração de raios X (DRX, espectroscopia Raman, microscopia eletrônica de transmissão e sorção de N2 (BET. Ênfase foi dada à quantificação das fases do compósito pela análise de DRX combinada ao método Rietveld. O estudo de adsorção foi realizado variando o pH do meio e a concentração do íon cádmio em solução. A análise dos resultados possibilitou verificar que a remoção de Cd(II utilizando compósito magnético Mn3O4/Fe3O4 em meio aquoso é dependente do pH duplicando a medida que o pH varia de 3 para 7. O estudo de imobilização do íon contaminante em solução apresentou valores significativos de capacidade máxima de adsorção, de 12,3 mgCd/g no pH 6 e 13,6 mgCd/g no pH 7, indicando uma remoção de até 98% para concentrações baixas do íon, sugerindo que o adsorvente apresenta elevado potencial para remoção de Cd(II em meio aquoso.

Peregrinação e alegoria: uma leitura doCompêndio Narrativo do Peregrino da América

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Jean Luiz Neves Abreu

Full Text Available Resumo:A obra de Nuno Marques Pereira, Compêndio narrativo do peregrino da América, publicada em 1728, pertence ao vasto repertório da literatura de cunho moralizante produzida entre os séculos XVI e XVIII. Trata-se da narrativa de viagem que um suposto "peregrino" faz da Baía de Todos os Santos à Capitania das Minas, na qual discorre sobre os costumes religiosos no Brasil e aborda temas diversos, analisados à luz de uma teologia moral. Este artigo propõe analisar como Nuno Marques Pereira articula elementos discursivos disponíveis na tradição, como é o caso da alegoria e do diálogo, e o exame dos costumes e das práticas religiosas que observa na sociedade da América Portuguesa no século XVIII, que atuam como elementos decisivos na construção do texto.

Reconnaître et valoriser les compétences "associatives" : les enjeux de la transmission dans l'accompagnement des parcours bénévoles

OpenAIRE

Tardif Bourgoin , Florence

2012-01-01

Atelier 22 : Travail social et bénévolat; Les exigences de professionnalisation dans le champ de l'action sociale préoccupent les associations dans un contexte de réduction des financements. Sont formulés des objectifs en vue de la qualification des bénévoles. Les dispositifs d'accompagnement qui se développent posent alors la question des transmissions mises en oeuvre : s'agit-il de transmettre une activité, des compétences, des valeurs ? Qu'en est-il du côté des Centres sociaux qui inscrive...

La professionnalisation de la formation universitaire d’enseignants de français : quelles compétences visées ?

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PHAM Duy Thien

2016-12-01

Full Text Available Bien former à un métier est devenu une préoccupation de la société vietnamienne. Car la qualité de la formation professionnelle laisse toujours à désirer. L’université dispensant traditionnellement des formations dites académiques les repense dans une perspective de professionnalisation. La logique académique et la logique professionnelle peuvent-elles être compatibles l’une avec l’autre ? Si la formation universitaire se professionnalise, qu’est-ce qu’elle apportera aux étudiants pour que ceux-ci, une fois diplômés, soient reconnus comme étant compétents et aptes à travailler ? Notre article propose de répondre à ces questions. Les réflexions qui y sont présentées proviennent de notre travail de thèse, portant sur la professionnalisation des guides touristiques vietnamiens.

Efeito de diferentes fotopolimerizadores e meio de imersão na rugosidade e na cor de um compósito nanoparticulado

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Suéllen Campos PLASTER

Full Text Available Resumo Introdução O consumo excessivo de refrigerantes parece alterar as propriedades dos compósitos e essa alteração pode estar relacionada à unidade fotopolimerizadora. Objetivo Avaliar a alteração da rugosidade superficial (ΔR e da cor (ΔE de um compósito polimerizado por diferentes fotopolimerizadores, imerso em água destilada ou Coca-Cola®. Metodologia Sessenta amostras da resina nanoparticulada (FiltekMR Z350 XT, 3M foram distribuídas de acordo com as diferentes unidades de fotopolimerização: a luz halógena de quartzo-tungstênio-halogênio (QTH; b Luz de Emissão Diodo - LED 1 com ponteira de polímero; c LED 2 com ponteira de fibra ótica. Metade de cada grupo (n=10 foi mantida em água destilada ou imersa em Coca-Cola® 2×/dia por 20 minutos, durante 14 dias. Os dados foram submetidos aos testes Mann-Whitney e Kruskal-Wallis (p≤0,05. Resultado A ΔR não foi significante entre os grupos: em água: QTH = 0,006; LED 1 = 0,019; LED 2 = 0,010 (p=0,33; em refrigerante: QTH = 0,021; LED 1= 0,011; LED 2 = 0,030 (p=0,86. A ΔE não foi significativa entre os fotopolimerizadores: em água: QTH = 1,40; LED 1 = 1,80; LED 2 = 1,60 (p=0,31; em refrigerante: QTH = 2,51; LED 1= 1,91; LED 2 = 2,61 (p=0,41, mas foi significante comparando os meios de imersão (p=0,01, exceto para LED 1 (p=0,54. Conclusão As unidades fotopolimerizadoras não interferiram na rugosidade superficial e na cor da resina composta nanoparticulada. Os mergulhos diários em refrigerante não alteraram a lisura, mas alteraram a cor de modo visualmente perceptível, mas clinicamente aceitável, conforme os parâmetros da literatura científica.

Earthquake Monitoring: SeisComp3 at the Swiss National Seismic Network

Science.gov (United States)

Clinton, J. F.; Diehl, T.; Cauzzi, C.; Kaestli, P.

2011-12-01

procedures, the nonlinloc algorithm was implemented for manual and automatic locations using 1D and 3D velocity models; plugins for improved automatic phase picking and Ml computation were developed; and the graphical user interface for manual review was extended (including pick uncertainty definition; first motion focal mechanisms; interactive review of station magnitude waveforms; full inclusion of strong motion data). SC3 locations are fully compatible with those derived from the existing in-house processing tools and are stored in a database derived from the QuakeML data model. The database is shared with the SED alerting software, which merges origins from both SC3 and external sources in realtime and handles the alerting procedure. With the monitoring software being transitioned to SeisComp3, acquisition, archival and dissemination of SED waveform data now conforms to the seedlink and ArcLink protocols and continuous archives can be accessed via SED and all EIDA (European Integrated Data Archives) web-sites. Further, a SC3 module for waveform parameterisation has been developed, allowing rapid computation of peak values of ground motion and other engineering parameters within minutes of a new event. An output of this module is USGS ShakeMap XML. n minutes of a new event. An output of this module is USGS ShakeMap XML.

Influência do método de polimerização na microdureza de compósitos microhíbridos armazenados em água destilada = Influence of curing method on the micro hardness of microhybrid composites immersed in distilled water

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Herbstrith Segundo, Regênio Mahfuz

2007-01-01

Full Text Available O objetivo do presente estudo é comparar e avaliar a microdureza Vickers de um compósito restaurador microhíbrido ativado por dois tipos de unidades polimerizadoras e armazenados em água destilada. Trinta espécimes foram feitos com resina Charisma B1, para cada um dos regimes de polimerização: fotopolimerização por luz halógena, fotopolimerização por LED e fotopolimerização mais ciclo adicional em autoclave. Foram feitas duas leituras de microdureza Vickers por corpo de prova em 1 dia, 7 dias e 14 dias de imersões. O ciclo adicional de polimerização mostrou uma tendência de aumentar os valores de microdureza dos compósitos restauradores, não mostrando diferenças estatisticamente significantes entre LED e Luz Halógena (p > 0,05

Integrated Physiological Mechanisms of Exercise Performance, Adaptation, and Maladaptation to Heat Stress

Science.gov (United States)

2011-10-01

en t 120 130 140 150 160 Marathon time, min 170 180 190 25 20 15 10 WBGT, °C Figure 11 Nomogram examining the potential performance decre- ment (y...otherwise healthy individuals participating in marathon and ultramarathon competition (81, 95, 168, 391), military training (132, 304), and recreational ...humans. J Appl Physiol 107: 1519-1525, 2009. 111. Ely MR, Cheuvront SN, Roberts WO, Montain SJ. Impact of weather on marathon -running performance

Caracterização Mecânica de Compósitos de Poliamida/Fibra de Carbono Via Ensaios de Cisalhamento Interlaminar e de Mecânica da Fratura Mechanical Characterization of Polyamide/Carbon Fiber Composites by Using Interlaminar Shear Strength and Fracture Mechanical Tests

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Edson C. Botelho

2002-01-01

Full Text Available Compósitos termoplásticos a partir de poliamidas 6 e 6,6 e tecido de fibras de carbono com 40, 50 e 60 % em volume de reforço foram processados via moldagem por compressão a quente e caracterizados por ensaios mecânicos destrutivos (cisalhamento interlaminar em três pontos (short-beam, cisalhamento interlaminar por compressão (CST e ensaios de mecânica da fratura e por inspeção não-destrutiva (ultra-som e microscopias óptica e eletrônica de varredura. Os resultados obtidos mostraram que os compósitos termoplásticos processados apresentaram uma distribuição homogênea do polímero no reforço. Entretanto, nos compósitos com maior quantidade de poliamida (40 % de reforço foram observadas regiões ricas em matriz entre as camadas de tecido. Os ensaios de mecânica da fratura (DCB e ENF e de cisalhamento interlaminar em três pontos não apresentaram falha interlaminar, não sendo observada a propagação de trincas de forma homogênea e retilínea no interior do material. Em função destes resultados foi utilizado o ensaio de cisalhamento por compressão, desenvolvido no Institute of Polymer Research Dresden da Alemanha, que permitiu uma caracterização mais precisa dos compósitos termoplásticos estudados. Foi observado também, a partir dos ensaios de CST, que os compósitos obtidos da poliamida 6,6 apresentaram um aumento no valor do cisalhamento interlaminar de até 20 % com o aumento do volume de fibras.Thermoplastics composites of polyamide 6 and 6.6 reinforced with carbon fiber fabric were obtained by compression molding and characterized by destructive (short-beam, compression shear (CST and fracture mechanics testing as well as by non-destructive inspection (ultrasound analysis, optical and scanning electron microscopy. The results show that, in general, the matrix was homogeneously distributed about the reinforcing fabric. However, for the composites with higher polyamide content (>50% matrix-rich regions were

Resistência mecânica de compósitos cimentícios leves utilizando resíduos industriais e fibras de sisal Mechanical resistence of lightweight cement composites utilizing industrial residues and fibers of sisal

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Nivaldo T. de Arruda Filho

2012-08-01

Full Text Available A valorização de materiais alternativos incorporados com resíduos como opção ao convencional deve possibilitar a geração de um produto com qualidade, estética, produtividade e com potencial de reduzir impactos da poluição ambiental. Este trabalho foi realizado com o objetivo de desenvolver elementos construtivos para forro e divisórias, a partir de matrizes cimentícias com incorporação de resíduos industriais (resíduo cerâmico, etil vinil acetato - EVA e fibras de sisal. Desenvolveram-se técnicas de moldagem em matrizes cimentícias autoadensáveis e se avaliou a resistência mecânica dos novos compósitos. Uma placa com resíduos de EVA foi produzida e, através de trabalhos de reologia, encontrou-se a pasta matriz de revestimento desta placa, com teor adequado de adições pozolânicas e aditivo superplastificante. Avaliaram-se as resistências mecânicas das placas, da pasta matriz de revestimento encontrada, com e sem adição de fibras, e do novo compósito formado pela união desses dois elementos. Utilizou-se a técnica de alinhamento de fibras com o intuito de incrementar resistência ao novo compósito leve. A adição da matriz com fibras alinhadas melhorou a resistência a flexão do novo compósito.The appreciation of alternative materials incorporated in waste as an option to conventional material should enable to generate a product with quality, aesthetics, productivity and reduce the potential impacts of environmental pollution. This study aims to develop constructive elements for ceilings and walls from cementitious matrix incorporating industrial waste (ceramic waste, ethyl vinyl acetate - EVA and sisal fibers. Moulding techniques to produce self-compacting cementitious matrices were developed and the strength of the new composites were evaluated. A plate with EVA waste was produced and through rheology studies, a matrix plaster for coating of plate surface was found, with appropriate content of pozzolanic and

Impregnação de filmes do compósito de policarbonato (PC e sílicagel (Si com corante fotocrômico em fluido supercrítico = Impregnation of composite from polycarbonate (PC and silica gel (Si films with photochromic dye in supercritical fluid

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Fernanda de Almeida Fin de Lima

2010-01-01

Full Text Available O objetivo deste trabalho foi estudar a impregnação do corante fotocromático Reversacol Graphit® em filmes do compósito de policarbonato (PC e sílica-gel (Si, com a finalidade de obter aplicações em lentes fotocrômicas. Filmes de PC puros também foramimpregnados nas mesmas condições, para verificar o efeito da adição de sílica-gel. Os filmes do compósito foram produzidos em proporções de Si:PC de 1:40 e 1:80 (m m-1, pelo método casting. Para a impregnação do corante Reversacol Graphit nos filmes obtidos foiutilizado o processo supercrítico, pela sua eficiência e benefícios. A impregnação foi feita nos tempos de 15, 30, 45, 60, 90, 120, 150 e 180 min. A temperatura e a pressão adotadas foram de 60ºC e 120 bar. A quantidade de pigmento impregnado nos filmes de Si:PC – 1:40e 1:80 (m m-1 foi de 29 e 23% de massa de corante por massa de compósito, respectivamente, e para o filme de PC puro foi de apenas 2,2% massa de corante por massa de compósito. Pelas análises térmicas, verificou-se que os filmes do compósito apresentarammaior estabilidade térmica. Pela técnica de microscopia eletrônica, observou-se que os filmes de PC puro e dos compósitos Si:PC – 1:40 e 1:80 (m m-1 apresentaram uma superfície lisa e homogênea.The aim of this work was to study the impregnation of the photochromic dye Reversacol Graphit® in composite films ofpolycarbonate (PC and silica gel, with the purpose of finding applications in photochromic lenses. Pure PC films were also impregnated in the same conditions, to verify the effect of the silica-gel addition. The composites films were produced in Si:PC ratios of 1:40 and 1:80 (m m-1, using the casting method . For the impregnation of the dye Reversacol Graphit in the obtained films, the supercritical process was used due to its efficiency and benefits. The impregnation was made in the times of 15, 30, 45, 60, 90, 120, 150 and 180 minutes. The adopted temperature and pressure

El programa “Regla y compás”. Una experiencia utilizando un software gratuito para generar ambientes de aprendizaje en matemática

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Zuleyka Suárez Valdes-Ayala

2004-12-01

Full Text Available The program “Regla y Compás” (“Ruler and Compasses” is useful to support the teaching of Math processes in geometry by means of a computer. One of the advantages it offers is that it may be obtained gratuitously in the internet. The way in which this type of programs allows for corporative and interdisciplinary work will by analyzed. For this purpose, the experiences obtained during the research project “Teaching high school mathematics whit free online software: The Ruler and Compasses case” will be discussed. The latter enabled the elaboration of tree manuals: “User's manual”, “Student's manual” and Teacher`s manual”. The objective is to facilitate the teaching of geometry through 32 practice and learning sessions.

77 FR 69627 - Findings of Research Misconduct

Science.gov (United States)

2012-11-20

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Research Misconduct... Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, grant R56 DK063025, and National... Physiol. 291(6):C1271-8, 2006 Am J. Physiol. Cell Physiol. 294(1):C295-305, 2008 J. Lipid Res. 42:1444...

Estudo da influência de tratamentos químicos da fibra de sisal nas propriedades de compósitos com borracha nitrílica Study of the influence from chemical treatments of sisal fibers on the properties of composites with nitrile rubber

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Marco A. Iozzi

2010-01-01

Full Text Available A influência de diferentes tratamentos das fibras de sisal nas propriedades dos compósitos de borracha nitrílica/fibras de sisal, e borracha nitrílica/carbonato de cálcio/fibras de sisal foi investigada. Os compósitos, com fibras curtas aleatoriamente distribuídas, foram processados em moinho de dois rolos e caracterizados através de ensaios mecânicos de resistência à tração, microscopia eletrônica de varredura (MEV, análise por termogravimetria (TG e calorimetria exploratória diferencial (DSC. O tratamento de mercerização das fibras levou a uma maior adesão na interface fibra/matriz. O uso combinado de 67 pcr de carbonato com 33 pcr de fibras de sisal mercerizadas produziu um compósito com aumento significativo no módulo de elasticidade e sem perda da resistência à tração de ruptura. Os resultados da análise térmica mostraram que os compósitos são termicamente estáveis até cerca de 300 °C. Os materiais obtidos possuem uma boa relação custo/benefício tornando promissora sua utilização.In this work, composites were produced with nitrile rubber and sisal fibers, and nitrile rubber with calcium carbonate and sisal fibers. The composites were processed on a two-roll mixing mill and their properties were investigated with regard to the influence of chemical treatments of the fibers. The composites, with short fibers randomly distributed, were characterized by mechanical analysis, scanning electron microscopy (SEM, thermogravimetric analysis (TGA and differential scanning calorimetry (DSC. Mercerization treatment of the fibers promoted increasing the adhesion between the fiber and the rubber matrix. The composites of nitrile rubber with 67 pcr of calcium carbonate and 33 pcr of mercerized sisal fibers showed the best mechanical properties. Thermal analysis demonstrated that the composites are thermally stable up to 300 °C. The materials developed have a good cost/benefit relationship making their utilization

Materiais compósitos à base de gesso contendo eva (Etileno Acetato de Vinila) e vermiculita: otimização de misturas e propriedades termomecânicas

OpenAIRE

Oliveira, Marilia Pereira de

2009-01-01

O gesso é um dos materiais de construção mais antigos que se tem conhecimento. Algumas de suas propriedades lhe confere vantagens como, resistência ao fogo, isolamentos térmico e acústico. Em virtude de ser um ligante menos agressivo ao ambiente que o cimento Portland, seu uso deve ser incentivado e novas aplicações estudadas. Este trabalho teve como objetivo estudar as propriedades físico-mecânicas e térmicas de compósitos à base de gesso com a incorporação de vermiculita e de...

Síntese de um poli (ácido âmico para aplicação como interfase em compósitos termoplásticos de alto desempenho Synthesis of a poly (amic acid for appplication as interphase in high performance thermoplastic composites

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Liliana B. Nohara

2004-06-01

Full Text Available O objetivo do presente trabalho é apresentar a síntese de um poli (ácido âmico (PAA a ser utilizado como formador de interfase no processamento de compósitos termoplásticos de alto desempenho. Os materiais compósitos termoplásticos constituídos de um reforço rígido e de uma matriz dúctil têm as suas propriedades mecânicas fortemente dependentes do mecanismo de transferência de carga fibra/matriz. Por esse motivo, a região da interface/interfase nos materiais compósitos possui um papel fundamental nas propriedades finais do material. O PAA surge como uma alternativa para melhorar a adesão fibra/matriz na região interfacial em compósitos de alto desempenho, constituídos de matrizes termoplásticas, reforçadas com fibras de carbono ou vidro. O PAA é utilizado na forma de sal, na preparação de suspensões poliméricas de matrizes termoplásticas. O PAA estudado neste trabalho foi sintetizado utilizando-se os reagentes BTDA e DHPr. Em seguida, o PAA foi convertido em PI por imidização em solução. Análises por FTIR mostram o sucesso da síntese do PAA e da sua conversão em PI. As técnicas de DSC e TGA determinaram as temperaturas de transição vítrea (~213 °C e de decomposição (~310 °C, respectivamente. Estes resultados motivam a utilização do PAA/PI como formador de interfase na obtenção de compósitos termoplásticos com temperaturas de processamento abaixo de 310 °C.This work is aimed at presenting the synthesis of a poly (amic acid (PAA to be used as interphase precursor in the manufacturing of high performance thermoplastic composites. Thermoplastic composites comprising a rigid reinforcement and a ductile matrix have their mechanical properties strongly dependent on the load transfer mechanism between the reinforcement and matrix. For this reason, the interface/interphase region plays a fundamental hole in the final properties of the composite materials. PAA appeared as an alternative to improve the

De la compétence de service aux compétences de coordination et d’orchestration : Autour du conseiller funéraire From service competency to coordination and orchestration skills: the funeral director De la competencia de servicio a las competencias de coordinación y de orquestación : el consejero fúnebre

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Sandrine Caroly

2006-05-01

Full Text Available Partir à la découverte du « conseiller funéraire », personnage emblématique de la profession de pompes funèbres, nous donne accès aux principaux registres de compétence des opérateurs funéraires, tout au long d’une prestation de service qui conjugue traitement du corps, service public et ritualité funéraire. Maître d’œuvre des obsèques, le conseiller se découvre historiquement comme une figure à géométrie variable, évoluant d’une fonction de personnage public, au cœur des réseaux notables et religieux de la communauté locale, à celle de conseiller technico-commercial, cependant de plus en plus investi d’un rôle « d’officiant » dans la production des funérailles comme bien culturel et symbolique. Cet article s’intéresse à la manière dont les compétences du conseiller funéraire sont mises en œuvre à travers trois principaux registres de compétence : la gestion de l’interaction avec le client, la coordination interprofessionnelle et enfin « l’orchestration » de l’événement et du sacré dans le déroulement des opérations funéraires. L’analyse de l’activité funéraire révèle des propriétés essentielles des compétences de service.In describing the funeral director, who is the symbol of funeral services, we gain access to the main skill registries of funeral operators during the entire provision of services, which include: the handling of the deceased, the public service, and the funeral ritual. As the individual who manages the funeral, the funeral director historically is a person with variable geometry, evolving from a public persona within the local community’s important religious networks to that of a technical and commercial consultant, but increasingly invested with the role of "officiant" in the production of funerals as cultural and symbolic property. This article is interested in how the funeral director’s skills are applied through three main skill registries

La compétition interspécifique entre la truite commune (Salmo trutta L. et la truite arc-en-ciel (Oncorhynchus Mykiss Walbaum : influence sur les modèles d'habitat

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BARAN P.

1995-04-01

Full Text Available L'influence de la compétition interspécifique sur l'occupation de l'habitat physique du ruisseau d'Estibère a été étudiée sur deux populations de truite arc-en-ciel (Oncorhynchus mykiss, vivant respectivement en allopatrie et en sympatrie avec une population de truite commune (Salmo trutta L.. Le taux d'occupation de la Surface Pondérée Utile (SPU calculée par la méthode des microhabitats (BOVEE, 1982 est significativement supérieur (t de Student, p < 0.05 pour la population allopatrique de truite arc-en-ciel par rapport à la population sympatrique. La surface d'abris, la pente et le taux d'occupation de la SPU par les truites communes permettent d'expliquer 77 % de la variation d'occupation de l'habitat physique par les adultes de truites arc-en-ciel. Pour les truites communes, la surface d'abris explique à elle seule, 81 % de la variation du taux d'occupation de l'habitat par les adultes. Selon l'espèce et le stade de développement considéré, la compétition interspécifique peut être un élément déterminant dans l'occupation de l'habitat physique potentiel.

Lysine and glutamate transport in the erythrocytes of common brushtail possum, Tammar Wallaby and eastern grey, kangaroo.

Science.gov (United States)

Ogawa, E; Kuchel, P W; Agar, N S

1998-04-01

It was recently coincidentally discovered, using 1H NMR spectroscopy, that the erythrocytes of two species of Australian marsupials, Tammar Wallaby (Macropus eugenii) and Bettong (Bettongia penicillata), contain relatively high concentrations of the essential amino acid lysine (Agar NS, Rae CD, Chapman BE, Kuchel PW. Comp Biochem Physiol 1991;99B:575-97). Hence, in the present work the rates of transport of lysine into the erythrocytes from the Common Brushtail Possum (Dactylopsilia trivirgata) and Eastern Grey Kangaroo (Macropus giganteus) (which both have low lysine concentrations), and Tammar Wallaby were studied, to explore the mechanistic basis of this finding. The concentration-dependence of the uptake was studied with lysine alone and in the presence of arginine, which may be a competitor of the transport in some species. In relation to GSH metabolism, glutamate uptake was determined in the presence and absence of Na+. The data was analysed to yield estimates of the maximal velocity (Vmax) and the Km in each of the species. Erythrocytes from Tammar Wallaby lacked saturable lysine transport in contrast to the other two species. The glutamate uptake was normal in all three animals for adequate GSH biosynthesis.

Collaboration in the competitive world of science: lessons to be learned from William T. Keeton.

Science.gov (United States)

Zupanc, Günther K H

2015-10-01

The tremendous increase in the number of authors and institutional affiliations on papers published in the natural sciences over the last few decades is commonly interpreted as an indicator of an increase in the collaborative spirit. However, a closer analysis suggests that this development reflects an increase in cooperation (defined as a strategy to divide labor among participants), rather than a rise in collaboration (defined as a mutual engagement of participants in a coordinated effort to jointly solve a problem). An exception to this development was William T. Keeton (1933-1980), who, as a faculty member at Cornell University, pioneered research into pigeon homing. A direct result of his willingness to openly share ideas and collaborate with other investigators is the article by Hagstrum and Manley (J Comp Physiol A, 2015) in this issue of the Journal of Comparative Physiology A. Their study is based on data from experiments Keeton and his collaborators conducted some 40 years ago. Despite the age of these data, their analysis and the interpretation of the results are likely to stimulate fruitful discussion in the field of avian orientation.

Propriedades reométricas e mecânicas e morfologia de compósitos desenvolvidos com resíduos elastoméricos vulcanizados Cure characteristics, mechanical properties and morphology of composites developed with addition of elastomeric vulcanized ground scraps

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Aline Zanchet

2007-03-01

Full Text Available Uma alternativa para as empresas geradoras de resíduos elastoméricos é a incorporação dos mesmos em suas formulações. Esse trabalho tem como objetivo preparar compósitos a partir da incorporação de resíduos industriais de SBR (copolímero de butadieno-estireno e de EPDM (terpolímero de etileno-propileno-dieno, em formulação ASTM específica para cada tipo de elastômero. Foram avaliadas as propriedades reométricas, mecânicas e morfológicas dos compósitos desenvolvidos. A incorporação do resíduo permitiu a obtenção de produtos que vulcanizam em menores tempos quando comparados a composições sem resíduo. A quantidade de resíduo, para o melhor resultado de resistência à tração foi de 37 e de 196 phr para os compósitos com SBR e EPDM, respectivamente. As micrografias de MEV corroboraram os resultados mecânicos dessas composições, indicando melhor homogeneidade do resíduo na respectiva matriz elastomérica.One alternative for elastomeric scraps generation is its incorporation in conventional formulations in the industry itself. In this work, compositions with incorporation of SBR (styrene butadiene rubber and EPDM (ethylene propylene diene rubber industrial scraps, in specific ASTM formulation for each elastomer, were prepared. Rheometric characteristics, mechanical properties and the morphology of the compounds developed were evaluated. With the ground scraps incorporation the vulcanization time decreases, comparing with compounds without ground scraps. The amount of scraps for the best tensile strength properties was 37 and 196 phr for SBR and EPDM compositions, respectively. Micrographs corroborated the mechanical results, indicating the best homogeneity of the scraps in the elastomeric matrix for these compositions.

Intercomparison of measurements of NO2 concentrations in the atmosphere simulation chamber SAPHIR during the NO3Comp campaign

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H. Fuchs

2010-01-01

Full Text Available NO2 concentrations were measured by various instruments during the NO3Comp campaign at the atmosphere simulation chamber SAPHIR at Forschungszentrum Jülich, Germany, in June 2007. Analytical methods included photolytic conversion with chemiluminescence (PC-CLD, broadband cavity ring-down spectroscopy (BBCRDS, pulsed cavity ring-down spectroscopy (CRDS, incoherent broadband cavity-enhanced absorption spectroscopy (IBB\\-CEAS, and laser-induced fluorescence (LIF. All broadband absorption spectrometers were optimized for the detection of the main target species of the campaign, NO3, but were also capable of detecting NO2 simultaneously with reduced sensitivity. NO2 mixing ratios in the chamber were within a range characteristic of polluted, urban conditions, with a maximum mixing ratio of approximately 75 ppbv. The overall agreement between measurements of all instruments was excellent. Linear fits of the combined data sets resulted in slopes that differ from unity only within the stated uncertainty of each instrument. Possible interferences from species such as water vapor and ozone were negligible under the experimental conditions.

Création et utilisation de ressources pédagogiques sur support numérique pour l'apprentissage d'une L2 : quelles compétences pour l'enseignant ? Designing and using digital learning resources for second language acquisition: what skills do teachers need?

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Paul Arthaud

2006-11-01

Full Text Available À l'Université de Technologie de Belfort-Montbéliard, des ressources pédagogiques sur support numérique ont été créées afin d'être intégrées au dispositif d'enseignement d'une UV d'anglais destinée à des élèves-ingénieurs. Dans le cadre d'une recherche-action, la nature et la fonction de ces ressources ont été établies à la lumière de connaissances théoriques, et les effets de leur intégration ont fait l'objet de mesures. Cet article se concentre sur les compétences qui ont été requises pour mettre en place ces ressources : compétences dans les domaines de la didactique des langues et de la création de pages HTML. Une ébauche de référentiel métier est proposée. Même si les résultats de cette expérience semblent positifs, la question demeure de savoir s'il est possible d'être en même temps enseignant et concepteur de ressources sur support numérique. Des éléments de réponse se trouvent peut-être davantage du côté de la gestion du temps, de la motivation et des savoir-faire relationnels que du seul côté des compétences informatiques. Cette expérience n'a nullement pour vocation de fixer les règles d'un exemple à suivre. Néanmoins, elle illustre le fait que la recherche-action peut être un moyen efficace de canaliser la diversité des motivations des enseignants impliqués dans des démarches innovantes et de promouvoir la responsabilité déontologique et épistémologique, ce qui contribuera à l'amélioration des pratiques d'enseignement.At the University of Technology of Belfort-Montbéliard, digital learning resources have been designed for and integrated with the pedagogical structure of an English credit course for engineering students. Within an action research procedure, the nature and functions of these resources have been established in the light of theoretical knowledge, and the effects of this integration have been assessed. This article focuses on the skills - in the fields of

L’exercice fédéré des compétences locales. À propos de la fonction de «chef de file» en droit des collectivités territoriales français

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Cédric Groulier

2009-06-01

Full Text Available La révision constitutionnelle du 28 mars 2003 a introduit dans le droit des collectivités territoriales un dispositif que l’on pourrait qualifier d’exercice fédéré des compétences locales. Selon l’article 72 alinéa 5 de la Constitution, lorsque l’exercice d’une compétence nécessite le concours de plusieurs collectivités territoriales, la loi peut autoriser l’une d’entre elles ou un de leurs groupements à organiser les modalités de leur action commune, autrement dit à exercer les fonctions de chef de file. À travers cette figure du chef de file, la Constitution semble admettre un principe de superposition entre collectivités territoriales, dérogeant à la règle de l’interdiction des tutelles entre collectivités, liée à leur liberté d’administration. Toutefois, la portée effective de ce nouveau dispositif repose sur sa mise en œuvre législative : or, le législateur fait montre d’une grande réserve, sans doute injustifiée, qui maintient l’idée de superposition entre collectivités à l’état de virtualité.

Compósito cimentício reforçado com fibras de carbono para recuperação de monumentos históricos Cementicious composites made with steatite residue reinforced with carbon fiber

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T. H. Panzera

2010-12-01

Full Text Available O intemperismo, como fenômeno natural, atinge não somente materiais produzidos pelo homem, como também construções feitas de rochas naturais. No entanto, a evolução intempérica geralmente ocorre em ritmo muito lento em relação à duração dos empreendimentos humanos. Contudo, há situações em que este se acelera, afetando as obras de engenharia, sobretudo as obras de arte, monumentos históricos e fachadas de igrejas consideradas patrimônio da humanidade. O presente trabalho investigou o efeito da adição de fibra de carbono em compósitos cimentícios de resíduos de esteatito visando à recuperação de peças confeccionadas com este mineral, popularmente conhecido como "pedra-sabão". As propriedades físico-mecânicas tais como, densidade volumétrica e resistência mecânica à flexão foram investigadas neste experimento. Concluiu-se que a adição de fibra de carbono aumenta significativamente a resistência mecânica dos compósitos além da redução de seu peso específico, permitindo o reaproveitamento de um maior percentual de resíduos de esteatito no compósito final.Weathering is a natural phenomenon that affects both the engineering materials and natural rocks used for construction. The weathering evolution generally occurs at a slow pace when compared with the overall durability of the construction elements. However, in some cases the weathering may develop much quicker, affecting the engineering constructions and also historical buildings such as monuments and churches. This work investigated the effect of carbon fibre addition into cementitious composites made with residues of steatite, a mineral, also known as soapstone, for restoration of craftwork elements. The material's properties, such as bulk density and flexural strength were investigated. It is possible to conclude that the carbon fibre addition increases the flexural strength of the composites and reduces the specific weight, allowing for the use of a

Influência da adição e da modificação química de uma carga mineral nanoparticulada nas propriedades mecânicas e no envelhecimento térmico de compósitos poliuretano/sisal Influence of a nanoparticulate mineral filler addition and chemical modification of the mechanical properties and thermal aging of PU/Sisal composites

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Maria Roberta O. Pinto

2005-11-01

Full Text Available Este trabalho trata do efeito da hibridização do reforço, através da adição de uma carga mineral (bentonita nanoparticulada, no desempenho mecânico de compósitos poliuretano/sisal contendo 25% em massa de fibras de sisal e moldados por compressão. As propriedades mecânicas, de tração e impacto, dos sistemas compósitos estudados foram avaliadas em função do teor (0-10% em massa e de modificações químicas da carga mineral. Os efeitos do envelhecimento térmico nas propriedades tênseis (sigma, E, épsilon de compósitos selecionados também foram investigados. O reforço mineral (Bentonita sódica Brasgel-PA foi empregado em quatro formas, a saber: a como fornecido (sem tratamento, b tratado com ácido clorídrico (0,6N, c modificado com cloreto de dodecil dimetil benzil amônio (Dodigen e d modificado com brometo de cetil trimetil amônio (Cetremide. Os resultados indicam que a incorporação da bentonita eleva as propriedades mecânicas dos compósitos e que melhores propriedades foram obtidas quando a bentonita foi tratada com o ácido clorídrico. O envelhecimento térmico em tempos curtos (até 4 dias provocou elevação no módulo elástico e resistência na ruptura dos compósitos, o que foi atribuído à pós-cura da matriz. Em tempos longos (32 dias a exposição térmica causou decréscimo nas propriedades tênseis (sigma, E, épsilon dos compósitos investigados, o que foi atribuído à degradação oxidativa da matriz e dos reforços. O compósito mais resistente ao envelhecimento térmico foi o híbrido cuja carga mineral foi organofilizada com o sal Cetremide. Anáslies por DRX e MEV indicam que a estrutura dos compósitos híbridos é um misto de micro e nanocompósito.This work deals with filler hybridization effects, by the addition of a nanoparticulate mineral filler (bentonite, on the mechanical performance of compression molded Polyurethane/sisal composites with 25 wt % fiber content. Composite tensile and

Viabilidade de utilização de um compósito de matriz cerâmica com cargas recicláveis na fabricação de equipamentos solares

OpenAIRE

Mota, Maria Kalionara de Freitas

2012-01-01

Foi concebido e estudado um compósito de matriz cerâmica composto por gesso, cimento, EPS, pneu, PET e água para construir protótipos solares competitivos em eficiência com outros equipamentos de materiais convencionais já construídos e estudados e de menor custo de fabricação. Foram construídos dois fornos/fogões solares tipo caixa, uma caixa térmica para ser refrigerada por energia solar, um secador solar e um fogão solar a concentração. Foram determinadas as proporções dos materiais ...

Factors in Maximal Power Production and in Exercise Endurance Relative to Maximal Power

Science.gov (United States)

1988-10-13

Mechanical efficiency of fast -and slow - twitch muscle fibers in mnan during cycling. J. ADLi Physiol.:Reespirat. Environ. Exercise Physiol. 47: 263- 267...R.S. Hikida, and F.C. Hagerman. Myofibrillar ATPase activity in hu-man muscle fast - twitch subtypes. Histochem. 78: 405-408, 1983. 31. Suzuki, Y...capacity and muscle fibre composition in mnan. J. Physiol (London) 354: 73P, 1984. 21. Margaria, R., P. Aghemo, and E. Rovelli. Measurement of muscular

Polimerização complementar em autoclave, microondas e estufa de um compósito restaurador direto = The effect of post-cure heating in autoclave, microwave oven and conventional oven on direct composite resin

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Arossi, Guilherme Anziliero

2007-01-01

Full Text Available Com o objetivo de tornar o processo de confecção de restaurações indiretas mais acessível, reduzindo seus custos com a resina utilizada e os métodos de polimerização complementar, este estudo testou a possibilidade de se utilizar resinas diretas com métodos de polimerização complementar alternativos. Corpos de prova foram confeccionados com a resina Charisma e fotopolimerizados por 20 segundos. Em seguida as amostras foram submetidas à polimerização complementar em autoclave, microondas e estufa. Foram estabelecidos dois grupos controles: um controle negativo, que consistiu na utilização da resina Charisma fotopolimerizada convencionalmente (20s; e um grupo controle positivo, formado por amostras do compósito restaurador indireto Targis. O ensaio de microdureza Knoop foi realizado após uma semana de armazenagem e os resultados submetidos à análise estatística. Os três métodos de polimerização complementar propostos determinaram um aumento na microdureza do compósito restaurador direto quando comparado ao controle negativo (p 0,05. Conclui-se que, considerando o desenho experimental deste estudo, a polimerização complementar em autoclave, microondas ou estufa aumenta a microdureza da resina Charisma previamente fotopolimerizada

Estudo das propriedades de compósitos biodegradáveis de amido/glúten de milho/glicerol reforçados com fibras de sisal Study of properties of biodegradable composites of starch/gluten/glycerol reinforced with sisal fibers

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Elisângela Corradini

2008-01-01

Full Text Available Neste estudo, fibras de sisal foram utilizadas como reforço para a matriz constituída de amido, glúten de milho e glicerol. O teor de fibra em relação a matriz variou de 5 a 30%. O processamento da matriz e dos compósitos foi realizado em um reômetro de torque Haake à 130 °C, 50 rpm por 10 minutos. As misturas obtidas foram moldadas por compressão à quente. As propriedades mecânicas; termodinâmico-mecânico (DMTA e de absorção de água foram investigadas em função do teor de fibras na matriz de amido/glúten de milho/glicerol. O aumento do conteúdo de fibra provocou uma melhoria nas propriedades mecânicas dos compósitos com relação à matriz. O compósito reforçado com 30% de fibra de sisal apresentou aumento no módulo de elasticidade e tensão na ruptura de aproximadamente de 560 e 162%, respectivamente e diminuição nos valores de elongação na ruptura de 81%. Os resultados obtidos por DMTA mostraram aumento progressivo do módulo de armazenamento (E' e diminuição do módulo de amortecimento (tan d com o aumento do teor de fibra, confirmando o efeito de reforço das fibras de sisal na matriz de amido/glúten de milho/glicerol. A incorporação das fibras na matriz também provocou diminuição da absorção de umidade e no coeficiente de difusão de água. A análise da morfologia dos compósitos mostrou boa dispersão das fibras na matriz.Biocomposites using starch/gluten/glycerol as matrix and sisal fibers were produced by melt-mixing in an intensive batch mixer connected to a torque rheometer at 130 °C. The samples were compression molded and than characterized by water absorption and mechanical test. In tensile test, the increasing in the Young's modulus and ultimate tensile strenght were respectively of aproximately 560 and 162% in relation to matrix, whereas elongation at break decreased. The storage modulus increased with increasing fiber content whereas tan d curves decreased, confirming the reinforcing

Effect of light curing tip distance and resin shade on microhardness of a hybrid resin composite Efeito da distância da ponta do aparelho de fotoativação e da cor na microdureza superficial de um compósito híbrido

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Flávio Henrique Baggio Aguiar

2005-12-01

Full Text Available Resin composite shades and resin composite polymerization performed with a distanced light tip are factors that can affect polymerization effectiveness. Thisin vitro study aimed to evaluate the influence of curing tip distance and resin shade on the microhardness of a hybrid resin composite (Z250 - 3M ESPE. Forty-five resin composite specimens were randomly prepared and divided into nine experimental groups (n = 5: three curing tip distances (2 mm, 4 mm, and 8 mm and three resin shades (A1, A3.5, and C2. All samples were polymerized with a continuous output at 550 mW/cm². After 24 hours, Knoop microhardness measurements were obtained on the top and bottom surfaces of the sample, with a load of 25 grams for 10 seconds. Five indentations were performed on each surface of each sample. Results showed that bottom surface samples light-cured at 2 mm and 4 mm presented significantly higher hardness values than samples light-cured at 8 mm. The resin shade A1 presented higher hardness values and was statistically different from C2. The resin shade A3.5 did not present statistical differences from A1 and C2. For the top surface, there were no statistical differences among the curing tip distances. For all experimental conditions, the top surface showed higher hardness values than the bottom surface. It was concluded that light curing tip distance and resin shade are important factors to be considered for obtaining adequate polymerization.A cor do compósito e a polimerização realizada com a ponta do aparelho de fotoativação distante da superfície do compósito são fatores que podem afetar a efetividade de polimerização. Assim, o objetivo deste estudo in vitro foi avaliar a influência desses fatores na microdureza superficial de um compósito híbrido (Z250 - 3M ESPE. Quarenta e cinco espécimes de compósito foram aleatoriamente preparados de acordo com os nove grupos experimentais (n = 5: três distâncias de fotoativação (2 mm, 4 mm e 8 mm e

Regulation of renal function and structure by the signaling Na/K-ATPase.

Science.gov (United States)

Xie, Jeffrey X; Li, Xin; Xie, Zijian

2013-12-01

The Na/K-ATPase as an essential ion pump was discovered more than 50 years ago (Skou (1989) Biochim. Biophys. Acta 1000, 439-446; Feraille and Doucet (2001) Physiol. Rev. 81, 345-418). The signaling function of Na/K-ATPase has been gradually appreciated over the last 20 years, first from the studies of regulatory effects of ouabain on cardiac cell growth. Several reviews on this topic have been written during the last few years (Schoner and Scheiner-Bobis (2007) Am. J. Physiol. Cell. Physiol. 293, C509-C536; Xie and Cai (2003) Mol. Interv. 3, 157 - 168; Bagrov et al. (2009) Pharmacol. Rev. 61, 9-38; Tian and Xie (2008) Physiology 23, 205-211; Fontana et al. (2013) FEBS J. 280, 5450-5455; Blanco and Wallace (2013) Am. J. Physiol. Renal Physiol. 305, F797-F812). This article will focus on the molecular mechanism of Na/K-ATPase-mediated signal transduction and its potential regulatory role in renal physiology and diseases. © 2013 International Union of Biochemistry and Molecular Biology.

Estudo experimental do reforço à flexão em vigas de concreto armado com balanço utilizando compósitos com tecidos de fibras de carbono

OpenAIRE

Araújo, Ana; Sánchez, Emil; Velasco, Marta

2004-01-01

Esse trabalho apresenta um estudo sobre o comportamento e o desempenho de vigas de concreto armado reforçadas à flexão utilizando-se compósitos de fibra de carbono. O programa experimental constituído pelo ensaio de sete vigas biapoiadas com um vão em balanço, todas com a mesma seção transversal, armaduras de aço e vãos idênticos, sendo o momento positivo máximo igual ao do momento negativo máximo. O concreto utilizado foi projetado para fornecer uma resistência à compressão de 20 MPa e o aço...

Detailing the relation between renal T2* and renal tissue pO2 using an integrated approach of parametric magnetic resonance imaging and invasive physiological measurements.

Science.gov (United States)

Pohlmann, Andreas; Arakelyan, Karen; Hentschel, Jan; Cantow, Kathleen; Flemming, Bert; Ladwig, Mechthild; Waiczies, Sonia; Seeliger, Erdmann; Niendorf, Thoralf

2014-08-01

This study was designed to detail the relation between renal T2* and renal tissue pO2 using an integrated approach that combines parametric magnetic resonance imaging (MRI) and quantitative physiological measurements (MR-PHYSIOL). Experiments were performed in 21 male Wistar rats. In vivo modulation of renal hemodynamics and oxygenation was achieved by brief periods of aortic occlusion, hypoxia, and hyperoxia. Renal perfusion pressure (RPP), renal blood flow (RBF), local cortical and medullary tissue pO2, and blood flux were simultaneously recorded together with T2*, T2 mapping, and magnetic resonance-based kidney size measurements (MR-PHYSIOL). Magnetic resonance imaging was carried out on a 9.4-T small-animal magnetic resonance system. Relative changes in the invasive quantitative parameters were correlated with relative changes in the parameters derived from MRI using Spearman analysis and Pearson analysis. Changes in T2* qualitatively reflected tissue pO2 changes induced by the interventions. T2* versus pO2 Spearman rank correlations were significant for all interventions, yet quantitative translation of T2*/pO2 correlations obtained for one intervention to another intervention proved not appropriate. The closest T2*/pO2 correlation was found for hypoxia and recovery. The interlayer comparison revealed closest T2*/pO2 correlations for the outer medulla and showed that extrapolation of results obtained for one renal layer to other renal layers must be made with due caution. For T2* to RBF relation, significant Spearman correlations were deduced for all renal layers and for all interventions. T2*/RBF correlations for the cortex and outer medulla were even superior to those between T2* and tissue pO2. The closest T2*/RBF correlation occurred during hypoxia and recovery. Close correlations were observed between T2* and kidney size during hypoxia and recovery and for occlusion and recovery. In both cases, kidney size correlated well with renal vascular conductance

Thermoregulatory Responses to Intermittent Exercise Are Influenced by Knit Structure of Underwear

Science.gov (United States)

1990-01-01

determined at 120 min, when Swo,(K3) and Swt(K4) were lower compared to both Sw,,(K2) and Swot (K5) 400 (Fig. 3). 300 Skin wettednessEE The knit...dew Pugh LGC (1966) Clothing insulation and accidential hypo- point temperature sensor. J Appl Physiol 52: 1658- 1660 thermia in youth. Nature 209: 1281...insulation. J Appl Physiol 8:539-545 cise and thermal stress. Physiol Rev 54:75-159 Hardy JI), )uBois EF (1938) Basal metabolism, radiation, Saltin B

Propriedades mecânicas de materiais compósitos à base de cimento Portland e resina epoxi Mechanical properties of composite materials based on portland cement and epoxy resin

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T. H. Panzera

2010-03-01

Full Text Available O estudo de materiais de alto desempenho e multifuncionais, como os compósitos poliméricos cimentícios, tem sido o foco de inúmeras pesquisas na indústria da construção civil. Este trabalho investiga o efeito da combinação de uma fase polimérica termorrígida, uma resina epóxi, com cimento Portland branco estrutural, seguido da avaliação da resistência à compressão e módulo de elasticidade. Este compósito, quando comparado individualmente com as suas matérias-prima originais, promove um aumento da resistência mecânica à compressão, redução da massa específica e, também uma mudança significativa do comportamento mecânico. As mudanças nas propriedades mecânicas estão associadas à hidratação da fase cimentícia na presença da resina, fato comprovado através da análise espectroscópica na região do infravermelho.The study of multi-functional materials of high performance, as the polymeric-cementitious composites, has been the focus of several researches in the industry of the civil engineering. This work investigates the effect of the combination of a thermorigid epoxy phase and the white Portland cement, followed by the evaluation of its compressive strength and modulus of elasticity. This composite, when the phases are individually compared, provides an increase of the compressive strength, a reduction of the density, and a significant change of the mechanical behaviour. The changes in mechanical behaviour are associated with the hydration of cement in the presence of resin, which was evident after infrared spectroscopy analysis.

Amino acid specificity of fibers of the facial/trigeminal complex innervating the maxillary barbel in the Japanese sea catfish, Plotosus japonicus.

Science.gov (United States)

Caprio, John; Shimohara, Mami; Marui, Takayuki; Kohbara, Jun; Harada, Shuitsu; Kiyohara, Sadao

2015-12-01

The Japanese sea catfish, Plotosus japonicus, possesses taste and solitary chemoreceptor cells (SCCs) located on the external body surface that detect specific water-soluble substances. Here, we identify two major fiber types of the facial/trigeminal complex that transmit amino acid information to the medulla. Both single and few fiber preparations respond to amino acid stimulation in the 0.1 μM to mM range. One fiber type responds best to glycine and l-alanine (i.e. Gly/Ala fibers) whereas the other fiber type is best stimulated by l-proline and glycine betaine (hereafter referred to only as betaine) (i.e. Pro/Bet fibers). We demonstrate that betaine, which does not alter the pH of the seawater and therefore does not activate the animals' highly sensitive pH sensors (Caprio et al., Science 344:1154-1156, 2014), is sufficient to elicit appetitive food search behavior. We further show that the amino acid specificity of fibers of the facial/trigeminal complex in P. japonicus is different from that in Ariopsis felis (Michel and Caprio, J. Neurophysiol. 66:247-260, 1991; Michel et al., J. Comp. Physiol. A. 172:129-138, 1993), a representative member of the only other family (Ariidae) of extant marine catfishes. Copyright © 2015 Elsevier Inc. All rights reserved.

Estudo das propriedades mecânicas e térmicas do polímero Poli-3-hidroxibutirato (PHB e de compósitos PHB/pó de madeira Study of mechanical and thermal properties of the polymer Poly-3-hydroxybutyrate (PHB and PHB/wood flour composites

Directory of Open Access Journals (Sweden)

Miriam L. C. Machado

2010-01-01

Full Text Available O PHB (Poli-3-hidroxibutirato é um termoplástico biodegradável sintetizado por fermentação submersa a partir de matérias-primas renováveis. A utilização de fibras naturais tem sido pesquisada visando melhorar as propriedades e reduzir o custo do PHB. O objetivo deste trabalho foi o estudo das propriedades mecânicas (resistência à tração, térmicas (Análise termogravimétrica,TGA, e Calorimetria Exploratória Diferencial, DSC e reológicas (torque em câmera de mistura e Índice de Fluidez do PHB e de compósitos de PHB/pó de madeira processados e irradiados. Foram preparados compósitos com concentrações de PHB/pó de madeira de 90/10, 80/20 e 70/30 (m/m. Os materiais foram processados através das seguintes etapas de processamento: calandragem, fragmentação, extrusão, granulação, secagem e moldagem por injeção para confecção dos corpos de prova. A incorporação do pó de madeira aumentou o grau de cristalinidade e a temperatura de cristalização do polímero, e nos compósitos PHB/pó de madeira 80/20 e 70/30 a rigidez do material aumentou. A irradiação após o processamento (dose de 30 kGy provocou aumento da rigidez do PHB puro e dos compósitos PHB/pó de madeira 90/10 e 80/20, embora outras propriedades tenham decrescido. O compósito PHB/pó de madeira 70/30 apresentou os melhores resultados em termos econômicos e de processamento.PHB (Polyhydroxybutyrate is a biodegradable thermoplastic synthesized by submerse fermentation of renewable raw materials. The use of natural fibers has been largely researched to improve PHB properties, as well as reducing its cost. The purpose of this work was the study of the mechanical, thermal properties and rheological analyses (torque in mixer camera and melt flow index of processed and irradiated PHB, as well as PHB/wood flour composites. PHB/wood flour composites were prepared with PHB/wood relation of 90/10, 80/20 and 70/30 (w/w. Both pure PHB and composites were

Étude de la technique d'échange ionique avec compétition. Cas du dépôt de platine sur support solide acide par échange cationique Research on the Ion Exchange Technique with Competition. Case of Platinum Deposit on a Solid Acid Support by Cation Exchange

Directory of Open Access Journals (Sweden)

Ribeiro F.

2006-11-01

Full Text Available Cet article présente une étude détaillée de la technique de dépôt de platine sur support acide par échange cationique avec compétition. Cette technique permet d'obtenir à la fois une dispersion quasi atomique et une répartition macroscopique homogène du métal sur la surface du solide. En l'absence de limitations diffusionnelles extra-granulaires, les résultats expérimentaux sont en bon accord avec les prévisions théoriques . This article is a detailed examination of the technique of depositing platinum on an acid support by cation exchange with compétition. This technique produces both a quasi-atomic dispersion and a homogeneous macroscopic distribution of the métal onthe surface of the solid. In the absence of extragranular diffusion limitations, experimental findings are in good agreement with theoretical predictions.

Numerical Integration Techniques for Curved-Element Discretizations of Molecule–Solvent Interfaces

Science.gov (United States)

Bardhan, Jaydeep P.; Altman, Michael D.; Willis, David J.; Lippow, Shaun M.; Tidor, Bruce; White, Jacob K.

2012-01-01

Surface formulations of biophysical modeling problems offer attractive theoretical and computational properties. Numerical simulations based on these formulations usually begin with discretization of the surface under consideration; often, the surface is curved, possessing complicated structure and possibly singularities. Numerical simulations commonly are based on approximate, rather than exact, discretizations of these surfaces. To assess the strength of the dependence of simulation accuracy on the fidelity of surface representation, we have developed methods to model several important surface formulations using exact surface discretizations. Following and refining Zauhar’s work (J. Comp.-Aid. Mol. Des. 9:149-159, 1995), we define two classes of curved elements that can exactly discretize the van der Waals, solvent-accessible, and solvent-excluded (molecular) surfaces. We then present numerical integration techniques that can accurately evaluate nonsingular and singular integrals over these curved surfaces. After validating the exactness of the surface discretizations and demonstrating the correctness of the presented integration methods, we present a set of calculations that compare the accuracy of approximate, planar-triangle-based discretizations and exact, curved-element-based simulations of surface-generalized-Born (sGB), surface-continuum van der Waals (scvdW), and boundary-element method (BEM) electrostatics problems. Results demonstrate that continuum electrostatic calculations with BEM using curved elements, piecewise-constant basis functions, and centroid collocation are nearly ten times more accurate than planartriangle BEM for basis sets of comparable size. The sGB and scvdW calculations give exceptional accuracy even for the coarsest obtainable discretized surfaces. The extra accuracy is attributed to the exact representation of the solute–solvent interface; in contrast, commonly used planar-triangle discretizations can only offer improved

Role of 5-hydroxytryptamine mechanisms in mediating the effects of small intestinal glucose on blood pressure and antropyloroduodenal motility in older subjects

NARCIS (Netherlands)

Gentilcore, Diana; Little, Tanya J.; Feinle-Bisset, Christine; Samsom, Melvin; Smout, Andre J. P. M.; Horowitz, Michael; Jones, Karen L.

2007-01-01

5-hydroxytryptamine mechanisms in mediating the effects of small intestinal glucose on blood pressure and antropyloroduodenal motility in older subjects. Am J Physiol Gastrointest Liver Physiol 293: G692-G698, 2007. First published August 9, 2007; doi:10.1152/ajpgi.00199.2007.-Postprandial

Spironolactone ameliorates transplant vasculopathy in renal chronic transplant dysfunction in rats

NARCIS (Netherlands)

Waanders, Femke; Rienstra, Heleen; Boer, Mark Walther; Zandvoort, Andre; Rozing, Jan; Navis, Gerjan; van Goor, Harry; Hillebrands, Jan-Luuk

Waanders F, Rienstra H, Walther Boer M, Zandvoort A, Rozing J, Navis G, van Goor H, Hillebrands JL. Spironolactone ameliorates transplant vasculopathy in renal chronic transplant dysfunction in rats. Am J Physiol Renal Physiol 296: F1072-F1079, 2009. First published February 25, 2009;

Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia

NARCIS (Netherlands)

Kroening, Sven; Neubauer, Emily; Wullich, Bernd; Aten, Jan; Goppelt-Struebe, Margarete

2010-01-01

Kroening S, Neubauer E, Wullich B, Aten J, Goppelt-Struebe M. Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia. Am J Physiol Renal Physiol 298:F796-F806, 2010. First published December 23, 2009;

Endothelial progenitor cell dysfunction in patients with progressive chronic kidney disease

NARCIS (Netherlands)

Krenning, Guido; Dankers, Patricia Y. W.; Drouven, Johannes W.; Waanders, Femke; Franssen, Casper F. M.; van Luyn, Marja J. A.; Harmsen, Martin C.; Popa, Eliane R.

Krenning G, Dankers PY, Drouven JW, Waanders F, Franssen CF, van Luyn MJ, Harmsen MC, Popa ER. Endothelial progenitor cell dysfunction in patients with progressive chronic kidney disease. Am J Physiol Renal Physiol 296: F1314-F1322, 2009. First published April 1, 2009; doi:

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African Journals Online (AJOL)

Dr Olaleye

of regional blood flow regulation and cardiovascular function in health and disease states. ... The PSS was bubbled throughout with 95% O2 - 5% CO2 gas mixture with the ..... transport of Mg2+ . Am. J Physiol Heart Cir Physiol. 300: H486-H492.

Annual Targets, UAVs and Range Operations Symposium and Exhibition (49th) Held in Fort Walton Beach, Florida on October 25-27, 2011

Science.gov (United States)

2011-10-27

COMP Mountain Home COMP Shaw COMP Barksdale COMP Hill COMP Homestead ARB COMP Savannah CRTC COMP Gulfport CRTC COMP Alpena CRTC COMP Montana...Spangdahlem AB Aviano AB Kadena AB Programmed: 165 Baseline Pods purchase in FY12 (del FY13) Alpena CRTC Holloman AFB Eielson AFB Planned: 368...ARQ-52(V)2 ARQ-52B(V)2 ARDS (HDIS) ASQ- T35A P4NS (NACTS-RSI) KITS (Kadena) ASQ-T34 ASQ-T46 AKITS ( Alpena ) Israel No Datalink No Datalink P4R1 ASQ

High Efficiency Heat Exchanger for High Temperature and High Pressure Applications

Energy Technology Data Exchange (ETDEWEB)

Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Lv, Qiuping [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division; Moisseytsev, Anton [Argonne National Lab. (ANL), Argonne, IL (United States). Nuclear Engineering Division

2017-09-29

CompRex, LLC (CompRex) specializes in the design and manufacture of compact heat exchangers and heat exchange reactors for high temperature and high pressure applications. CompRex’s proprietary compact technology not only increases heat exchange efficiency by at least 25 % but also reduces footprint by at least a factor of ten compared to traditional shell-and-tube solutions of the same capacity and by 15 to 20 % compared to other currently available Printed Circuit Heat Exchanger (PCHE) solutions. As a result, CompRex’s solution is especially suitable for Brayton cycle supercritical carbon dioxide (sCO2) systems given its high efficiency and significantly lower capital and operating expenses. CompRex has already successfully demonstrated its technology and ability to deliver with a pilot-scale compact heat exchanger that was under contract by the Naval Nuclear Laboratory for sCO2 power cycle development. The performance tested unit met or exceeded the thermal and hydraulic specifications with measured heat transfer between 95 to 98 % of maximum heat transfer and temperature and pressure drop values all consistent with the modeled values. CompRex’s vision is to commercialize its compact technology and become the leading provider for compact heat exchangers and heat exchange reactors for various applications including Brayton cycle sCO2 systems. One of the limitations of the sCO2 Brayton power cycle is the design and manufacturing of efficient heat exchangers at extreme operating conditions. Current diffusion-bonded heat exchangers have limitations on the channel size through which the fluid travels, resulting in excessive solid material per heat exchanger volume. CompRex’s design allows for more open area and shorter fluid proximity for increased heat transfer efficiency while sustaining the structural integrity needed for the application. CompRex is developing a novel improvement to its current heat exchanger design where fluids are directed to alternating

Theory of Synaptic Plasticity in Visual Cortex.

Science.gov (United States)

1992-12-23

15 Hubel, D. H. and Wiesel, T. N. (1959). Integrative action in the cat’s lateral geniculate body . J. Physiol, 148:574-591. Hubel, D. H. and Wiesel, T...of these afferents derive from the lateral geniculate nucleus (LGN) and from other cortical neurons. We have approached the analysis of this complex...agreement with what is seen experimentally. 3.2 Neurobiological Foundations for the Assumptions of the BCM Theory Recent advances in our understanding of

To Ensure the Integrity of the Cryogenic Propellant Depot Tank Within the Expected Radiation and Space Debris Environment, Phase II

Data.gov (United States)

National Aeronautics and Space Administration — HyPerComp Engineering, Inc. (HEI) proposes to develop well characterized, structurally reliable filament wound composite pressure vessels for use in both cryogenic...

Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis

NARCIS (Netherlands)

Schaffert, Courtney S.; Duryee, Michael J.; Bennett, Robert G.; DeVeney, Amy L.; Tuma, Dean J.; Olinga, Peter; Easterling, Karen C.; Thiele, Geoffrey M.; Klassen, Lynell W.

Schaffert CS, Duryee MJ, Bennett RG, DeVeney AL, Tuma DJ, Olinga P, Easterling KC, Thiele GM, Klassen LW. Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis. Am J Physiol Gastrointest Liver Physiol 299: G661-G668, 2010. First published July 1, 2010; doi:

Circulating microRNAs as diagnostic biomarkers for cardiovascular diseases

NARCIS (Netherlands)

Tijsen, Anke J.; Pinto, Yigal M.; Creemers, Esther E.

2012-01-01

Tijsen AJ, Pinto YM, Creemers EE. Circulating microRNAs as diagnostic biomarkers for cardiovascular diseases. Am J Physiol Heart Circ Physiol 303: H1085-H1095, 2012. First published August 31, 2012; doi:10.1152/ajpheart.00191.2012.-One of the major challenges in cardiovascular disease is the

L-NIL prevents renal microvascular hypoxia and increase of renal oxygen consumption after ischemia-reperfusion in rats

NARCIS (Netherlands)

Legrand, Matthieu; Almac, Emre; Mik, Egbert G.; Johannes, Tanja; Kandil, Asli; Bezemer, Rick; Payen, Didier; Ince, Can

2009-01-01

Legrand M, Almac E, Mik EG, Johannes T, Kandil A, Bezemer R, Payen D, Ince C. L-NIL prevents renal microvascular hypoxia and increase of renal oxygen consumption after ischemia-reperfusion in rats. Am J Physiol Renal Physiol 296: F1109-F1117, 2009. First published February 18, 2009;

Análise do efeito higrotérmico no comportamento em fadiga de compósitos de PPS/fibras de carbono On the analysis of hygrothermal effect on fatigue behavior of PPS/carbon fiber composite

Directory of Open Access Journals (Sweden)

Maria C. M. de Faria

2012-01-01

Full Text Available O contínuo crescimento na utilização de compósitos termoplásticos em componentes estruturais na indústria aeroespacial deve-se, primordialmente, à flexibilidade de projeto, excelência de suas propriedades mecânicas e baixa massa específica, aliadas aos elevados valores de resistência mecânica e rigidez e baixa incidência de corrosão, atendendo aos severos requisitos de desempenho quando em serviço dessas estruturas. Componentes com exigências estruturais, quando expostos a ambientes agressivos como elevada temperatura e umidade, podem ter suas propriedades mecânicas sensibilizadas por esses fatores ambientais, e devem ser cuidadosamente avaliados antes de serem colocados em serviço. Em função do que foi exposto este trabalho tem como objetivo contribuir para a avaliação do efeito higrotérmico na resistência à fadiga do compósito termoplástico PPS/fibras de carbono. Os materiais estudados foram cedidos pela empresa holandesa TenCate, fornecedora de laminados da Airbus e EMBRAER. Os resultados obtidos neste trabalho mostram que compósitos de PPS/fibras de carbono apresentam um aumento nos valores de resistência à tração quando condicionados higrotermicamente, devido à plasticização desta matriz polimérica, aumentando, consecutivamente, sua tenacidade à fratura. Entretanto, a partir dos ensaios realizados, foi constatado que o condicionamento higrotérmico não alterou de forma significativa o comportamento de vida em fadiga dos laminados PPS-C.The continued growth in the use of polymer composites in structural components in the aerospace industry is due primarily to the design flexibility, excellent mechanical properties and low density, combined with the high values of mechanical strength and stiffness and low incidence of corrosion, with which these structures meet several performance requirements when in service. Components with structural requirements may have their mechanical properties affected when

Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time

NARCIS (Netherlands)

Kramer, Andrea B.; van Timmeren, Mirjan M.; Schuurs, Theo A.; Vaidya, Vishal S.; Bonventre, Joseph V.; van Goor, Harry; Navis, Gerjan

Kramer AB, van Timmeren MM, Schuurs TA, Vaidya VS, Bonventre JV, van Goor H, Navis G. Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time. Am J Physiol Renal Physiol 296: F1136-F1145, 2009. First published February

Differential effects of NF-kappa B and p38 MAPK inhibitors and combinations thereof on TNF-alpha- and IL-1 beta-induced proinflammatory status of endothelial cells in vitro

NARCIS (Netherlands)

Kuldo, JM; Westra, J; Asgeirsdottir, SA; Kok, RJ; Oosterhuis, K; Rots, MG; Schouten, JP; Limburg, PC; Molema, G

Differential effects of NF- kappa B and p38 MAPK inhibitors and combinations thereof on TNF-alpha- and IL- 1 beta- induced proinflammatory status of endothelial cells in vitro. Am J Physiol Cell Physiol 289: C1229 - C1239, 2005. First published June 22, 2005; doi: 10.1152/ ajpcell. 00620.2004.

Sur la reconnaissance de la compétence exclusive des groupements religieux afin d‘instaurer leur structure intrinsèque et les normes intérieures des relations en tant qu’une des garanties ...

Directory of Open Access Journals (Sweden)

Philip Ryabykh

2012-11-01

SOMMAIRE: 1. Brève histoire de l’affaire – 2. Préambule – 3. Protection de la compétence exclusive des groupements religieux en vue d’instaurer leur structure intrinsèque et les normes intérieures des relations au point de vue de la législation de la Roumanie – 4. Application du principe de l’autonomie des groupements religieux et du principe de l’inadmissibilité d’intervenir pour l’État aux affaires intérieures des groupements religieux – 5. Non-contradiction de la Convention des exigences intérieures des groupements religieux sur la loyauté et la conformité des personnes se trouvant dans les relations de service avec le groupement religieux – 6. Absence des raisons fournies par les faits juridiques suffisantes et justifiant réellement l’assimilation (la mise au même niveau des groupements religieux avec n’importe quelles autres organisations-employeurs dans la sphère de la réglementation des relations de travail – 7. Légalité de l’instauration des restrictions à la création et les activités des syndicats dans les certaines sphères des relations publiques – 8. Compétence de la Roumanie de fixer dans la législation les restrictions à la liberté des syndicats conformément à la sphère des relations religieuses – 9. Signification des résultats du jugement de l’affaire «Syndicat “Le Bon Pasteur” c. Roumanie» (requête 2330/09 pour L’Église Orthodoxe Russe- 10. Conclusion.

Modificação de fibra de carbono com PBLH e sua utilização em compósitos com resina epoxídica Hydroxyl-terminated polybutadiene-grafted carbon fiber in epoxy resin-based composites

Directory of Open Access Journals (Sweden)

Fábio L. Barcia

1999-06-01

Full Text Available Fibras de carbono contendo 1,4 e 2,1mmol/g de grupos carboxila e hidroxila fenólica, respectivamente, foram modificadas através de reação com TDI, resultando em fibras contendo 3,1 mmol/g de grupos isocianato. A introdução de grupos isocianato na superfície da fibra tornou possível a sua modificação com polibutadieno líquido hidroxilado. Fibras de carbono modificadas e não modificadas foram empregadas na preparação de compósitos com resina epoxídica, sendo observado um aumento considerável de resistência ao impacto em compósitos constituídos de fibras de carbono enxertadas com PBLH, devido, provavelmente, à natureza elastomérica da interface e à melhor adesão interfacial.Carbon fibers containing 1,4 e 2,1 mmol/g of carboxyl and phenolic hydroxyl groups, respectively, were modified through the reaction with TDI. The presence of isocyanate groups at the fiber surface made possible the fiber modification with hydroxyl terminated polybutadiene (HTPB. These modified and unmodified carbon fibers were employed in the preparation of epoxy resin-based composites. A substantial improvement in the impact properties was observed in the composites with HTPB-grafted carbon fibers when compared to unmodified carbon fibers. These results may be attributed to a higher interfacial adhesion promoted by reactions between the functional groups present at the modified carbon fiber surface and the epoxy matrix.

Role of Spironolactone Chalcone in the Prevention of Peritoneal ...

African Journals Online (AJOL)

Results: Spironolactone chalcone treatment at a dose of 30 mg/kg body ... fibrosis in PD patients using various drugs and ... Rockville, Maryland, USA) cultures in a brain– ... mL blood samples were collected from the vena .... The transport barrier in intraperitoneal therapy. Am J Physiol Renal Physiol 2005; 288: F433-. 442.

Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex

NARCIS (Netherlands)

Taherzadeh, Zhila; VanBavel, Ed; de Vos, Judith; Matlung, Hanke L.; van Montfrans, Gert; Brewster, Lizzy M.; Seghers, Leonard; Quax, Paul H. A.; Bakker, Erik N. T. P.

2010-01-01

Taherzadeh Z, VanBavel E, de Vos J, Matlung HL, van Montfrans G, Brewster LM, Seghers L, Quax PH, Bakker EN. Strain-dependent susceptibility for hypertension in mice resides in the natural killer gene complex. Am J Physiol Heart Circ Physiol 298: H1273-H1282, 2010. First published February 12, 2010;

Compétition pour l'azote inorganique entre le pelagos et le benthos dans un écosystème côtier oligotrophe. Effets sur la dynamique de l'écosystème.

OpenAIRE

Lepoint, Gilles

2001-01-01

Résumé de la thèse intitulée : Compétition pour l’azote inorganique entre le benthos et le pelagos d’un milieu côtier oligotrophe. Effets sur la dynamique de l’écosystème. Dissertation présentée le 9 mai 2001 par Gilles Lepoint en vue de l’obtention du grade de Docteur en Sciences de l’Université de Liège. Dans la Baie de la Revellata (Calvi, Corse, France), comme dans de nombreux sites côtiers méditerranéens, les biocénoses benthiques sont très développées et productives, malgré le c...

Electrotonic vascular signal conduction and nephron synchronization

DEFF Research Database (Denmark)

Marsh, D.J.; Toma, I.; Sosnovtseva, Olga

2009-01-01

Marsh DJ, Toma I, Sosnovtseva OV, Peti-Peterdi J, Holstein-Rathlou NH. Electrotonic vascular signal conduction and nephron synchronization. Am J Physiol Renal Physiol 296: F751-F761, 2009. First published December 30, 2008; doi:10.1152/ajprenal.90669.2008.-Tubuloglomerular feedback (TGF) and the ......Marsh DJ, Toma I, Sosnovtseva OV, Peti-Peterdi J, Holstein-Rathlou NH. Electrotonic vascular signal conduction and nephron synchronization. Am J Physiol Renal Physiol 296: F751-F761, 2009. First published December 30, 2008; doi:10.1152/ajprenal.90669.2008.-Tubuloglomerular feedback (TGF......) and the myogenic mechanism control afferent arteriolar diameter in each nephron and regulate blood flow. Both mechanisms generate self-sustained oscillations, the oscillations interact, TGF modulates the frequency and amplitude of the myogenic oscillation, and the oscillations synchronize; a 5: 1 frequency ratio...... is the most frequent. TGF oscillations synchronize in nephron pairs supplied from a common cortical radial artery, as do myogenic oscillations. We propose that electrotonic vascular signal propagation from one juxtaglomerular apparatus interacts with similar signals from other nephrons to produce...

A 3-D Approach for Teaching and Learning about Surface Water Systems through Computational Thinking, Data Visualization and Physical Models

Science.gov (United States)

Caplan, B.; Morrison, A.; Moore, J. C.; Berkowitz, A. R.

2017-12-01

Understanding water is central to understanding environmental challenges. Scientists use `big data' and computational models to develop knowledge about the structure and function of complex systems, and to make predictions about changes in climate, weather, hydrology, and ecology. Large environmental systems-related data sets and simulation models are difficult for high school teachers and students to access and make sense of. Comp Hydro, a collaboration across four states and multiple school districts, integrates computational thinking and data-related science practices into water systems instruction to enhance development of scientific model-based reasoning, through curriculum, assessment and teacher professional development. Comp Hydro addresses the need for 1) teaching materials for using data and physical models of hydrological phenomena, 2) building teachers' and students' comfort or familiarity with data analysis and modeling, and 3) infusing the computational knowledge and practices necessary to model and visualize hydrologic processes into instruction. Comp Hydro teams in Baltimore, MD and Fort Collins, CO are integrating teaching about surface water systems into high school courses focusing on flooding (MD) and surface water reservoirs (CO). This interactive session will highlight the successes and challenges of our physical and simulation models in helping teachers and students develop proficiency with computational thinking about surface water. We also will share insights from comparing teacher-led vs. project-led development of curriculum and our simulations.

Statistical analysis plan for the Pneumatic CompREssion for PreVENting Venous Thromboembolism (PREVENT) trial: a study protocol for a randomized controlled trial.

Science.gov (United States)

Arabi, Yaseen; Al-Hameed, Fahad; Burns, Karen E A; Mehta, Sangeeta; Alsolamy, Sami; Almaani, Mohammed; Mandourah, Yasser; Almekhlafi, Ghaleb A; Al Bshabshe, Ali; Finfer, Simon; Alshahrani, Mohammed; Khalid, Imran; Mehta, Yatin; Gaur, Atul; Hawa, Hassan; Buscher, Hergen; Arshad, Zia; Lababidi, Hani; Al Aithan, Abdulsalam; Jose, Jesna; Abdukahil, Sheryl Ann I; Afesh, Lara Y; Dbsawy, Maamoun; Al-Dawood, Abdulaziz

2018-03-15

The Pneumatic CompREssion for Preventing VENous Thromboembolism (PREVENT) trial evaluates the effect of adjunctive intermittent pneumatic compression (IPC) with pharmacologic thromboprophylaxis compared to pharmacologic thromboprophylaxis alone on venous thromboembolism (VTE) in critically ill adults. In this multicenter randomized trial, critically ill patients receiving pharmacologic thromboprophylaxis will be randomized to an IPC or a no IPC (control) group. The primary outcome is "incident" proximal lower-extremity deep vein thrombosis (DVT) within 28 days after randomization. Radiologists interpreting the lower-extremity ultrasonography will be blinded to intervention allocation, whereas the patients and treating team will be unblinded. The trial has 80% power to detect a 3% absolute risk reduction in the rate of proximal DVT from 7% to 4%. Consistent with international guidelines, we have developed a detailed plan to guide the analysis of the PREVENT trial. This plan specifies the statistical methods for the evaluation of primary and secondary outcomes, and defines covariates for adjusted analyses a priori. Application of this statistical analysis plan to the PREVENT trial will facilitate unbiased analyses of clinical data. ClinicalTrials.gov , ID: NCT02040103 . Registered on 3 November 2013; Current controlled trials, ID: ISRCTN44653506 . Registered on 30 October 2013.

A model of frequency tuning in the basilar papilla of the Tokay gecko, Gekko gecko.

Science.gov (United States)

Authier, S; Manley, G A

1995-01-01

This paper uses the quantitative details of the anatomy of the auditory papilla in the Tokay gecko Gekko gecko (as described in the companion paper) to make a quantitative model predicting the tonotopic organization of two of the three papillar areas. Assuming that hair-cell bundle stiffness is similar to that of other species, a model of resonance frequencies for the apical areas of the papilla was constructed, taking into account factors such as the number of hair cells per resonant unit, their bundle dimensions, the volume of the tectorial mass, etc. The model predicts that the apical pre- and postaxial areas, although anatomically adjacent, respond to different frequency ranges, a phenomenon not yet reported from any vertebrate. The model predicts that together, these areas respond best to frequencies between 1.1 and 5.3 kHz, close to the range found physiologically [Eatock et al. (1981) J. Comp. Physiol. 142, 203-218] (0.8 to 5 kHz) for the high-frequency range for this species. Only physiological experiments tracing responses to specific papillar nerve fibres can confirm or refute these interesting predictions of the model. The model also indicates that, compared to free-standing hair-cell bundles, the semi-isolated tectorial structures called sallets not only lower the range of characteristic frequencies but also increase the frequency selectivity of the attached hair cells.

Learned helplessness: validity and reliability of depressive-like states in mice.

Science.gov (United States)

Chourbaji, S; Zacher, C; Sanchis-Segura, C; Dormann, C; Vollmayr, B; Gass, P

2005-12-01

The learned helplessness paradigm is a depression model in which animals are exposed to unpredictable and uncontrollable stress, e.g. electroshocks, and subsequently develop coping deficits for aversive but escapable situations (J.B. Overmier, M.E. Seligman, Effects of inescapable shock upon subsequent escape and avoidance responding, J. Comp. Physiol. Psychol. 63 (1967) 28-33 ). It represents a model with good similarity to the symptoms of depression, construct, and predictive validity in rats. Despite an increased need to investigate emotional, in particular depression-like behaviors in transgenic mice, so far only a few studies have been published using the learned helplessness paradigm. One reason may be the fact that-in contrast to rats (B. Vollmayr, F.A. Henn, Learned helplessness in the rat: improvements in validity and reliability, Brain Res. Brain Res. Protoc. 8 (2001) 1-7)--there is no generally accepted learned helplessness protocol available for mice. This prompted us to develop a reliable helplessness procedure in C57BL/6N mice, to exclude possible artifacts, and to establish a protocol, which yields a consistent fraction of helpless mice following the shock exposure. Furthermore, we validated this protocol pharmacologically using the tricyclic antidepressant imipramine. Here, we present a mouse model with good face and predictive validity that can be used for transgenic, behavioral, and pharmacological studies.

Study of surface alterations of composite and ionomeric materials submitted to simulation of a high cariogenic challenge Estudo da erosão superficial de materiais compósitos e inoméricos submetidos à simulação de um alto desafio cariogênico

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Alexandre Rezende VIEIRA

1999-12-01

Full Text Available We evaluated the surface of composite resins and glass-ionomer cements in a situation of high cariogenic challenge. Based on seventy-five standard test specimens of one glass-ionomer cement (Chelon Fil - ESPE, one resin-modified glass-ionomer (Vitremer - 3M, two polyacid-modified composite (VariGlass and Dyract - Dentsply and one composite resin (Heliomolar - Vivadent, submitted to fourteen days of demineralization and remineralization cycling to simulate a high cariogenic challenge, the erosive aspects of the surface of the materials were assessed. All of the samples were evaluated by scanning electronic microscope and compared with another five test specimens of each material, prepared in the same way and serving as control. All of the materials studied suffered erosive action by the media, with different characteristics due to the different compositions, after being submitted to in vitro simulation of a high cariogenic challenge.O objetivo deste trabalho foi avaliar a superfície de compósitos e cimentos de ionômero de vidro, frente a uma situação de alto desafio cariogênico. A partir de setenta e cinco corpos-de-prova padronizados de um cimento de ionômero de vidro (Chelon Fil - ESPE, um ionômero de vidro resina-modificado (Vitremer - 3M, dois compósitos poliácido-modificados (VariGlass e Dyract - Dentsply e um compósito (Heliomolar - Vivadent, e após serem submetidos a quatorze dias a ciclagens de desmineralização e remineralização, para simular um alto desafio cariogênico, foram avaliados os aspectos erosivos da superfície dos materiais. Todos os corpos-de-prova foram avaliados ao microscópio eletrônico de varredura e comparados com cinco outros corpos-de-prova de cada material, confeccionados da mesma forma e que serviram como controle. Todos os materiais estudados sofreram ação erosiva dos meios, com características distintas, devido às suas diferentes composições, após serem submetidos à simulação in vitro

Estudo das propriedades elétricas e térmicas de compósitos nanoestruturados de poli(sulfeto de fenileno reforçados com nanotubos de carbono

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Bruno Ribeiro

2015-02-01

Full Text Available Neste trabalho o comportamento de cristalização e a condutividade elétrica de compósitos nanoestruturados de poli(sulfeto de fenileno reforçado com nanotubos de carbono de paredes múltiplas obtidos através da técnica de mistura em fusão foram estudados. A incorporação do nanoreforço na matriz polimérica foi responsável por um aumento da cristalinidade devido ao fenômeno de nucleação heterogênea. A condutividade elétrica do PPS apresentou um aumento de 11 ordens de magnitude quando 2,0 m/m% de MWCNT foram adicionados a matriz polimérica. Além disso, o limite de percolação elétrica encontrado para este sistema foi de 1,4 m/m% de MWCNT, revelando a formação de uma rede condutiva tridimensional no interior da matriz polimérica.

Cartilage oligomeric matrix protein specific antibodies are pathogenic

DEFF Research Database (Denmark)

Geng, Hui; Nandakumar, Kutty Selva; Pramhed, Anna

2012-01-01

-specific monoclonal antibodies (mAbs). METHODS: B cell immunodominant regions on the COMP molecule were measured with a novel enzyme-linked immunosorbent assay using mammalian expressed full-length mouse COMP as well as a panel of recombinant mouse COMP fragments. 18 mAbs specific to COMP were generated......ABSTRACT: INTRODUCTION: Cartilage oligomeric matrix protein (COMP) is a major non-collagenous component of cartilage. Earlier, we developed a new mouse model for rheumatoid arthritis using COMP. This study was undertaken to investigate the epitope specificity and immunopathogenicity of COMP...

A first comparison of irregularity and ion drift velocity measurements in the E-region

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R. A. Makarevich

2006-09-01

Full Text Available E-region irregularity velocity measurements at large flow angles with the STARE Finland coherent VHF radar are considered in context of the ion and electron velocity data provided by the EISCAT tristatic radar system, CUTLASS Finland coherent HF radar, and IMAGE fluxgate magnetometers. The data have been collected during a special experiment on 27 March 2004 during which EISCAT was scanning between several E- and one F-region altitudes along the magnetic field line. Within the E-region, the EISCAT measurements at two altitudes of 110 and 115 km are considered while the electron velocity is inferred from the EISCAT ion velocity measurements at 278 km. The line-of-sight (l-o-s VHF velocity measured by STARE _{VHF los} is compared to the ion and electron velocity components (V_{i0 comp} and V_{e0 comp} along the STARE l-o-s direction. The comparison with V_{e0 comp} for the entire event shows that the measurements exhibit large scatter and small positive correlation. The correlation with V_{e0 comp} was substantial in the first half of the interval under study when V_{e0 comp} was larger in magnitude. The comparison with V_{i0 comp} at 110 and 115 km shows a considerable positive correlation, with VHF velocity being typically larger (smaller in magnitude than V_{i0 comp} at 110 km (115 km so that V_{VHF los} appears to be bounded by the ion velocity components at two altitudes. It is also demonstrated that the difference between V_{VHF los} and V_{i0 comp} at 110 km can be treated, in the first approximation, as a linear function of the effective backscatter height h_eff also counted from 110 km; h_eff varies in the range 108–114 km due to the altitude integration effects in the scattering cross-section. Our results are consistent with the notion that VHF

DNR Land Records Search Portal

Science.gov (United States)

- ENGINEERING PLAT FILE 311 - AK STATE LAND SUR 312 - UNORGANIZED BOROUGH 313 - RECORD OF SURVEY 314 - EASEMENT - ARCHAEOLOGICAL SITE 513 - PARK USE PERMIT 521 - SUBDIVISION SALE COMP 522 - AGRICULTURAL SALE COMP 523 - ODDLOT UPLAND 539 - OTHER SALE NON-COMP 541 - SUBDIVISION LEASE COMP 542 - AGRICULTURAL LEASE COMP 543 - ODDLOT

Une formation à distance pour la certification des compétences à l’ère du numérique : le projet C2i Université Laval - Université de Bordeaux

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Jean-François Lévesque

2010-01-01

Full Text Available Il est désormais devenu indispensable de maîtriser les technologies de l’information et de la communication (TIC pour entreprendre avec succès des études universitaires. Sur ce point, la prise de conscience est de plus en plus forte et la question de la certification des compétences requises à l’ère du numérique devient un enjeu pour les universités. À partir d’un projet pilote mené dans le cadre de la collaboration internationale entre l’Université Laval (Québec et l’Université de Bordeaux (France, nous nous interrogeons dans cet article sur les conditions de mise en place d’une formation à distance en réponse à cette préoccupation.

Avaliação da temperatura de transição vítrea de compósitos poliméricos reparados de uso aeronáutico Evaluation of glass transition temperature of the repaired polymeric composites of aeronautical use

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Jane M. F. de Paiva

2006-03-01

Full Text Available Este trabalho mostra a avaliação da temperatura de transição vítrea (Tg, por DMTA, de três famílias de compósitos poliméricos reparados, tendo como laminados base tecidos de fibras de carbono/resina epóxi modificada com elastômero (F584, vidro/resina epóxi (F161 e aramida/resina epóxi (F161. Os compósitos foram laminados manualmente por processo convencional e curados em autoclave de indústria aeronáutica. Posteriormente, danos foram simulados sendo, em seguida, reparados adotando-se a técnica de sobreposição de camadas de pré-impregnados de resina epóxi (F155, com adição de filme adesivo de epóxi (FM 73. As curvas DMTA mostram os efeitos da combinação de diferentes sistemas de resinas na Tg e, conseqüentemente, na temperatura de serviço do componente reparado. O material de reparo utilizado, baseado em pré-impregnados com resina epóxi F155 e filme adesivo de epóxi, provocou a redução da Tg dos compósitos reparados. Para os laminados base com tecido de fibras de carbono e vidro foram verificadas reduções de aproximadamente 30 °C na Tg. Este efeito foi mais pronunciado (redução de aproximadamente 40 °C quando o laminado reparado de aramida foi submetido a condicionamento higrotérmico a temperatura e umidade elevadas. Esta redução na Tg dos laminados reparados é atribuída à migração do adesivo para o pré-impregnado de resina epóxi F155 utilizado no reparo, durante o processo de cura, e à plasticização do sistema polimérico pela água, durante o condicionamento higrotérmico. A redução da Tg leva a uma conseqüente redução da temperatura de serviço do compósito polimérico reparado.This work shows the evaluation of the glass transition temperature (Tg by DMTA of three different families of repaired polymeric composites, manufactured with carbon fiber fabric/epoxy F584, glass fabric/epoxy F161 and aramide fabric/epoxy F161, respectively. The composites were laminated by conventional hand

Caracterização mecânica e morfológica de compósitos de polipropileno e fibras de coco verde: influência do teor de fibra e das condições de mistura Mechanical and morphological characterization of polypropylene and green coconut fiber composites: influence of fiber content and mixture conditions

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Marina H. Ishizaki

2006-01-01

Full Text Available Compósitos de polipropileno com 10, 20 e 30% em volume de fibra de coco verde foram obtidos em câmara de mistura Haake, tendo como variáveis a temperatura de processamento e a velocidade de cisalhamento. O módulo de flexão e as características morfológicas dos diferentes compósitos obtidos foram avaliados e comparados com o polipropileno puro. Foi observado que a temperatura de 170 °C, a velocidade do rotor de 60rpm e o teor de fibra de coco verde de 30% forneceram o melhor desempenho quanto à flexão. Essas observações foram comprovadas pela análise da morfologia.Polypropylene composites containing 10, 20 and 30% in volume of green coconut fiber were prepared in a Haake chamber at various processing temperatures and shear rates. The flexural modulus and morphological characteristics of the composites were evaluated and compared with pure polypropylene. Optimization experiments indicated that a temperature of 170 °C, shear rate of 60rpm and green coconut fiber content of 30% showed the best properties by flexural modulus. These observations were confirmed by a morphology analysis.

Wireless coordinated multicell systems architectures and precoding designs

CERN Document Server

Nguyen, Duy H N

2014-01-01

This SpringerBrief discusses the current research on coordinated multipoint transmission/reception (CoMP) in wireless multi-cell systems. This book analyzes the structure of the CoMP precoders and the message exchange mechanism in the CoMP system in order to reveal the advantage of CoMP. Topics include interference management in wireless cellular networks, joint signal processing, interference coordination, uplink and downlink precoding and system models. After an exploration of the motivations and concepts of CoMP, the authors present the architectures of a CoMP system. Practical implementati

Comportamento balístico de compósito de polietileno de altíssimo peso molecular: efeito da radiação gama Ballistic behaviour of ultra-high molecular weight polyethylene: effect of gamma radiation

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Andreia L. S. Alves

2004-06-01

Full Text Available Os materiais compósitos de matriz polimérica (PMCs reforçados por fibras são considerados excelentes materiais de engenharia. Em aplicações estruturais, quando uma elevada relação resistência peso é fundamental para o projeto, os PMCs vêm substituindo com sucesso diversos materiais convencionais. Materiais têxteis são utilizados, desde a 2ª Guerra Mundial, como blindagens balísticas. Materiais fabricados com fibra do polietileno de altíssimo peso molecular (UHMWPE são empregados na produção de blindagens, para proteção pessoal e em carros de combate. Todavia, em virtude de terem sido desenvolvidos e comercializados mais recentemente, não existem informações suficientes sobre o desempenho balístico desses materiais após a sua exposição aos agentes ambientais. No presente trabalho foi estudado o comportamento balístico de placas compósitas fabricadas com fibra de polietileno de altíssimo peso molecular (UHMWPE, após sua exposição à radiação gama. Os resultados dos testes balísticos foram relacionados com as alterações macromoleculares induzidas pela irradiação por meio de ensaios mecânicos (dureza, impacto e flexão e físico-químicos (espectroscopia no infravermelho, calorimetria diferencial de varredura e análise termogravimétrica. Foi verificado que a irradiação gama provoca modificações nas cadeias macromoleculares do polímero, que alteram as propriedades mecânicas do compósito de UHMWPE, reduzindo, nas doses de radiação mais elevadas, o seu desempenho balístico. Estes resultados são apresentados e discutidos.The fiber reinforced polymer matrix composites (PMCs are considered excellent engineering materials. In structural applications, when a high strength-to-weight ratio is fundamental for the design, PMCs are successfully replacing many conventional materials. Since World War II textile materials have been used as ballistic armor. Materials manufactured with ultrahigh molecular weight

Efeito da degradação ambiental nas propriedades de cisalhamento de compósitos PPS/fibra de carbono Effect of environmental degradation on shear properties of PPS /carbon fiber composites

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Anahi P. Costa

2011-01-01

Full Text Available Os compósitos termoplásticos avançados são uma alternativa a compósitos termorrígidos em algumas aplicações aeronáuticas, devido a ganhos em propriedades. Dentre as matrizes termoplásticas, o PPS (poli sulfeto de fenileno destaca-se devido às suas características estruturais. O objetivo deste trabalho é avaliar a influência do condicionamento ambiental sobre o comportamento de resistência ao cisalhamento de PPS / fibras de carbono. Por esta razão, amostras deste material foram condicionadas em solução salina, em banho higrotérmico e sob radiação UV. Após estes condicionamentos os corpos-de-prova foram avaliados quanto a sua resistência aos cisalhamentos interlaminar (ILSS e Iosipescu e os resultados obtidos foram comparados. Quando comparado ao valor de cisalhamento interlaminar obtido do compósito não-climatizado (58,4 ± 1,9 MPa, os valores de cisalhamento interlaminar ILSS decaíram em torno de 14 e 3%, respectivamente, após banho higrotérmico e banho salino. Sob condicionamento por radiação UV houve um decréscimo de 2% após exposição por 300 horas, 11% após 600 horas e 9% após 900 horas. Já o laminado ensaiado pelo método Iosipescu teve uma tensão de cisalhamento no plano de 109,2 ± 0,4 MPa. Com condicionamentos, teve um decréscimo de 6% após banho higrotérmico e 12% após banho salino. A exposição à radiação UV provocou na resistência de cisalhamento no plano um decaimento de 6% para o condicionamento de 300 horas, 10% para o condicionamento de 600 horas e 14% para o condicionamento por 900 horas.Advanced thermoplastic composites are an alternative to thermoset composites in many aeronautical applications owing to their superior properties. Among the thermoplastic matrix, PPS (poly phenylene sulfide stands out due to its structural characteristics. The objective of this study is to evaluate the influence of environmental conditioning on the shear behavior of PPS / carbon fiber composites

Preparação de fibras de polipropileno modificadas com grupos mercaptan e sua utilização em compósitos com resina epoxídica

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Dutra Rita C. L.

1999-01-01

Full Text Available Fibras de polipropileno modificadas com grupos mercaptan foram desenvolvidas através de processo de extrusão/fiação de misturas contendo PP e EVA modificado com grupos mercaptan (EVASH. A superfície destas fibras foi analisada por espectroscopia foto-eletrônica de raios-X (XPS, espectroscopia no infravermelho com transformada de Fourier, utilizando-se a técnica de refletância difusa (DRIFTS, tensão superficial e microscopia eletrônica de varredura. A partir destas técnicas, chegou-se à conclusão que o componente polar (EVASH se situa próximo à superfície da fibra. A utilização destas fibras em compósitos com resina epoxídica resultou em aumento considerável da resistência ao impacto e da temperatura de transição vítrea do material, indicando boa adesão interfacial matriz-fibra. Estas interações foram comprovadas por análise dinâmico-mecânicas.

Pulmonary Stress Induced by Hyperthermia: Role of Airway Sensory Nerves

Science.gov (United States)

2016-01-01

Myers AC, Kajekar R, Undem BJ. Allergic inflammation-induced neuropeptide production in rapidly adapting afferent nerves in guinea pig airways. Am J...induced neuro- peptide production in rapidly adapting afferent nerves in guinea pig airways. Am. J. Physiol. Lung Cell. Mol. Physiol. 282, L775–L781...co-localization of transient receptor po- tential vanilloid (trpv)1 and sensory neuropeptides in the guinea - pig respiratory system. Neuroscience

Cartilage oligomeric matrix protein associates differentially with erosions and synovitis and has a different temporal course in cyclic citrullinated peptide antibody (anti-CCP)-positive versus anti-CCP-negative early rheumatoid arthritis

DEFF Research Database (Denmark)

Christensen, Anne F; Lindegaard, Hanne; Hørslev-Petersen, Kim

2011-01-01

-suppressive effect. We aimed to compare circulating cartilage oligomeric matrix protein (COMP), a marker of cartilage turnover, in untreated anti-CCP-positive and anti-CCP-negative RA, and to study the temporal pattern of COMP through 4 years of treatment, including the relationship to imaging and clinical findings.......048). In anti-CCP-positive patients, COMP exhibited a parabolic course over 4 years, while COMP in anti-CCP-negative patients had an almost linear course. In anti-CCP-positive patients, COMP was associated with MRI edema and erosion score, while COMP was correlated with synovitis score in anti...

RNAi reduces expression and intracellular retention of mutant cartilage oligomeric matrix protein.

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Karen L Posey

2010-04-01

Full Text Available Mutations in cartilage oligomeric matrix protein (COMP, a large extracellular glycoprotein expressed in musculoskeletal tissues, cause two skeletal dysplasias, pseudoachondroplasia and multiple epiphyseal dysplasia. These mutations lead to massive intracellular retention of COMP, chondrocyte death and loss of growth plate chondrocytes that are necessary for linear growth. In contrast, COMP null mice have only minor growth plate abnormalities, normal growth and longevity. This suggests that reducing mutant and wild-type COMP expression in chondrocytes may prevent the toxic cellular phenotype causing the skeletal dysplasias. We tested this hypothesis using RNA interference to reduce steady state levels of COMP mRNA. A panel of shRNAs directed against COMP was tested. One shRNA (3B reduced endogenous and recombinant COMP mRNA dramatically, regardless of expression levels. The activity of the shRNA against COMP mRNA was maintained for up to 10 weeks. We also demonstrate that this treatment reduced ER stress. Moreover, we show that reducing steady state levels of COMP mRNA alleviates intracellular retention of other extracellular matrix proteins associated with the pseudoachondroplasia cellular pathology. These findings are a proof of principle and the foundation for the development of a therapeutic intervention based on reduction of COMP expression.

Investigating the role of feedback and motivation in clinical reaction time assessment.

Science.gov (United States)

Eckner, James T; Chandran, Srikrishna; Richardson, James K

2011-12-01

To investigate the influence of performance feedback and motivation during 2 tests of simple visuomotor reaction time (RT). Cross-sectional, observational study. Outpatient academic physiatry clinic. Thirty-one healthy adults (mean [SD], 54 ± 15 years). Participants completed a clinical test of RT (RT(clin)) and a computerized test of RT with and without performance feedback (RT(compFB) and RT(compNoFB), respectively) in randomly assigned order. They then ranked their degree of motivation during each test. RT(clin) measured the time required to catch a suspended vertical shaft by hand closure after release of the shaft by the examiner. RT(compFB) and RT(compNoFB) both measured the time required to press a computer key in response to a visual cue displayed on a computer monitor. Performance feedback (visual display of the previous trial and summary results) was provided for RT(compFB), but not for RT(compNoFB). Means and standard deviations of RT(clin), RT(compFB), and RT(compNoFB) and participants' self-reported motivation on a 5-point Likert scale for each test. There were significant differences in both the means and standard deviations of RT(clin), RT(compFB), and RT(compNoFB) (F(2,60) = 81.66, P motivation between RT(clin) and RT(compFB), both of which were reported to be more motivating than RT(compNoFB). The stronger correlation between RT(clin) and RT(compFB) as well as the higher reported motivation during RT(clin) and RT(compFB) testing suggest that performance feedback is a positive motivating factor that is inherent to RT(clin) testing. RT(clin) is a simple, inexpensive technique for measuring RT and appears to be an intrinsically motivating task. This motivation may promote faster, more consistent RT performance compared with currently available computerized programs, which do not typically provide performance feedback. Copyright © 2011 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

Influência de diferentes condições higrotérmicas na resistência à tração de compósitos de fibra de carbono/epóxi modificada Influence of different hygrothermal conditions on the tensile strength of carbon/epoxy 8552 composites

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José Antônio P. Cunha

2006-01-01

Full Text Available Este trabalho foi direcionado para a análise dos efeitos higrotérmicos na resistência à tração de compósitos poliméricos termorrígidos. Foram investigados os efeitos da umidade e da temperatura sobre as resistências à tração longitudinal e à tração transversal de compósitos ([0/0]s de fita de carbono unidirecional impregnada com resina epóxi 8552. Os ensaios de resistência à tração longitudinal, realizados à temperatura ambiente, mostraram que as amostras não perderam sua resistência quando condicionadas. Porém, os compósitos apresentaram uma redução na sua resistência quando submetidos à câmara de climatização (80 °C e 90% de umidade e ensaiados à temperatura elevada. Já nos ensaios de tração transversal foi observado que as amostras submetidas à câmara de névoa salina e ensaiadas à temperatura ambiente apresentaram uma pequena redução na sua resistência, porém as amostras submetidas à câmara de climatização mostraram uma redução acentuada na resistência As amostras ensaiadas à temperatura elevada e submetidas à câmara de névoa salina apresentaram uma pequena diminuição na sua resistência (11%. Já uma acentuada diminuição da resistência à tração transversal (51% foi observada quando as amostras de compósitos poliméricos foram submetidas à câmara de climatização e ensaiadas à temperatura elevada. Também foram obtidas fotomicrografias via microscopia eletrônica de varredura (MEV das seções de fraturas das amostras ensaiadas em tração em todos os tipos de condicionamento estudados no presente trabalho. Todos estes fatos mostraram que a matriz polimérica é afetada nos ensaios à temperatura elevada.This work focused the analysis of hygrothermal ageing effects on the tensile strength of thermoset laminated composites. Humidity and temperature effects on the longitudinal and transversal tensile strengths of carbon fiber/epoxy 8552 unidirectional laminates tape

Les albums de jeunesse en langues étrangères, un moyen détourné pour développer les compétences inférentielles et interprétatives des élèves ?

OpenAIRE

Isoz, Annick; Gremaud, Coralie; Deschoux, Carole-Anne

2016-01-01

Les albums en langues étrangères peuvent-ils être une entrée pour développer les compétences inférentielles et interprétatives? De nombreux élèves présentent des difficultés en compréhension écrite. Or lorsqu’on se penche sur la question, nous constatons que cette dernière est très peu enseignée et que les élèves ont souvent une représentation erronée de ce qu’est l’acte de lire. Ils la réduisent à une compréhension mot à mot et ne prennent pas en compte les dimensions inférentielles et inter...

Preparação e caracterização do compósito PVDF/Pani com partículas de níquel

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Gabriel da Cruz Dias

Full Text Available Resumo Neste trabalho partículas de níquel foram incorporadas através da mistura física do pó resultante da mistura PVDF/Pani obtido por síntese química. Filmes homogêneos foram obtidos através da prensagem a temperatura de 180°C. A partir dos resultados pode-se notar alterações favoráveis e desfavoráveis nas propriedades do compósito após a incorporação e como estas tornam-se dependentes da incorporação. Os resultados de difratometria apresentaram picos característicos tanto da fase α da matriz polimérica e das partículas de níquel, e juntamente com as analises térmicas, que não há alteração na estrutura conformacional e a configuracional. Mesmo apresentando uma boa estabilidade térmica a incorporação indica que além da presença do polímero condutor como o aumento de partículas são prejudiciais às propriedades mecânicas finais da amostra. As micrografias apresentam as partículas de forma dispersas ao longo do filme e determinantes para os valores de condutividade elétrica e obtenção de uma fase magnética.

Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis

DEFF Research Database (Denmark)

Geng, Hui; Carlsen, Stefan; Nandakumar, Kutty

2008-01-01

ABSTRACT: INTRODUCTION: Cartilage oligomeric matrix protein (COMP) is a homopentameric protein in cartilage. The development of arthritis, like collagen-induced arthritis (CIA), involves cartilage as a target tissue. We have investigated the development of CIA in COMP-deficient mice. METHODS: COMP......-deficient mice in the 129/Sv background were backcrossed for 10 generations against B10.Q mice, which are susceptible to chronic CIA. COMP-deficient and wild-type mice were tested for onset, incidence, and severity of arthritis in both the collagen and collagen antibody-induced arthritis models. Serum anti......-collagen II and anti-COMP antibodies as well as serum COMP levels in arthritic and wild-type mice were measured by enzyme-linked immunosorbent assay. RESULTS: COMP-deficient mice showed a significant early onset and increase in the severity of CIA in the chronic phase, whereas collagen II-antibody titers were...

Materiais compósitos particulados em matriz epóxi reforçados com serragem, cimento e silicato de magnésio

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Zélia Maria Velloso Missagia

Full Text Available Este trabalho tem como objetivo investigar propriedades físicas (densidade volumétrica e absorção de água e mecânicas (módulo de elasticidade e resistência à compressão de materiais compósitos particulados em matriz epóxi reforçados com serragem de madeira, cimento Portland e silicato de magnésio. Um planejamento experimental inicial foi elaborado envolvendo apenas a resina epóxi e a serragem de madeira. Posteriormente, elegeu-se o tratamento que forneceu os maiores valores para o módulo de elasticidade na compressão. Sobre a condição escolhida, foram desenvolvidas outras quatro, incorporando-se 10% e 20% em frações mássicas de partículas de silicato de magnésio e cimento Portland sobre a resina. Os compostos com 30% de serragem de madeira Eucalyptus grandis e faixa granulométrica 50-80 US-Tyler apresentaram os melhores valores para o módulo de elasticidade na compressão, sendo utilizados como condição de referência para a inclusão das partículas de cimento e do talco. O emprego do cimento nos compostos conferiu aumentos significativos no módulo de elasticidade à compressão, densidade e redução na absorção de água.

Exercise Performance of Sea-Level Residents at 4300 m After 6 Days at 2200 m

Science.gov (United States)

2009-11-01

commercially available energy bars and fruit juice (food composition 5 510 kcal, 14 gm fat, 65 gm carbohydrate, 32 gm protein) at 1 to 2 h prior to the...Intermittent altitude exposures improve muscular performance at 4300 m . J Appl Physiol 2003 ; 95 : 1824 – 32 . 3. Beidleman BA, Muza SR...in volumes of blood, plasma and red cell in dehydration . J Appl Physiol 1974 ; 37 : 247 – 8 . 8. Evans WO, Robinson SM, Horstman DH

Physical Activity, Aging, and Physiological Function.

Science.gov (United States)

Harridge, Stephen D R; Lazarus, Norman R

2017-03-01

Human evolution suggests that the default position for health is to be physically active. Inactivity, by contrast, has serious negative effects on health across the lifespan. Therefore, only in physically active people can the inherent aging process proceed unaffected by disuse complications. In such individuals, although the relationship between age and physiological function remains complex, function is generally superior with health, well being, and the aging process optimized. ©2017 Int. Union Physiol. Sci./Am. Physiol. Soc.

Effects of Simulated Pathophysiology on the Performance of a Decision Support Medical Monitoring System for Early Detection of Hemodynamic Decompensation in Humans

Science.gov (United States)

2017-02-01

Physiol 97: 1272-1280, 2012. 554 44. Serrador JM, Picot PA, Rutt BK, Shoemaker JK, and Bondar RL. MRI measures of middle 555 cerebral artery diameter in...artery diameter during hypocapnia and 567 hypercapnia in humans using ultra high-field MRI . J Appl Physiol 117: 1084-1089, 2014. PMID: 25190741. 568...in chronically instrumented rats. Journal of Cardiovascular Pharmacology 21: 829-833, 1993. 26. Leonetti P, Audat F, Girard A, Laude D, Lefrère F

Biocompatibility, osteointegration, osteoconduction, and biodegradation of a hydroxyapatite-polyhydroxybutyrate composite

Directory of Open Access Journals (Sweden)

Emily Correna Carlo Reis

2010-08-01

Full Text Available In this work, biocompatibility, osteointegration, osteoconductivity, and biodegradation of a hydroxyapatite polyhydroxybutyrate new composite were evaluated. The composite was implanted in rabbits' bone defects and clinical, radiographic, histological, and histomorphometric data of these animals were compared with those of unfilled defects on the days 8th, 45th, and 90th after surgery. No significant differences existed between the groups for the evaluated clinical parameters. Radiographs showed bone-composite direct contact. Bone formed within the defect, interface and inside the composite. Significant differences were found between the bone and connective tissues percentage within the defect at all dates and at the interface on the 45th day, bone tissue prevailing. Composite's biodegradation signs were evident: giant cells on the surface of composite fragments separated from the original block in the absence of inflammatory infiltrate. These data supported that such composite was biocompatible, biodegradable, osteoconductive and integrate to bone.A biocompatibilidade, osteointegração, osteocondução e biodegradação de um novo compósito de hidroxiapatita e polihidroxibutirato foram avaliados. O compósito foi implantado em defeitos ósseos em coelhos e dados clínicos, radiográficos, histológicos e histomorfométricos foram comparados aos de defeitos não preenchidos aos 8, 45 e 90 dias após a cirurgia. Não foram observadas diferenças significantes entre os grupos para os parâmetros clínicos avaliados. Contato direto entre osso e compósito foi observado nas radiografias. Tecido ósseo se formou dentro do defeito, interface e dentro do compósito. Foram observadas diferenças significativas entre a porcentagem dos tecidos ósseo e conjuntivo dentro do defeito em todas as datas de avaliação e na interface aos 45 dias, com predominância do tecido ósseo. Sinais de biodegradação foram observados: células gigantes na superf

Êtres capables et compétents : lecture anthropologique et pistes pragmatiques

Directory of Open Access Journals (Sweden)

Fabrizio Cantelli

2008-04-01

Full Text Available Les termes « compétences » et « capacités » occupent depuis quelques années une place de plus en plus importante dans le vocabulaire de la sociologie, notamment de la sociologie pragmatique. On les retrouve toutefois aussi dans d’autres champs théoriques (le terme capabilities chez Amartya Sen ou dans le vocabulaire des politiques publiques qui évoquent des politiques de « capacitation », ou des « seuils de compétences ». Face à ce constat, l’article développe l’hypothèse d’un véritable tournant anthropologique dont l’éclaircissement oblige à réfléchir sur de nouveaux frais les ambiguïtés des coordonnées anthropologiques sur lesquelles s’est bâtie la seconde modernité, celle qui s’ouvre aux alentours du 18e siècle. Rappelant à quel point le vocabulaire de la « capacité » était déjà inscrit dans les repères anthropologiques du 18e et du 19e siècles, fondant alors une disjonction stricte des êtres, accordant aux uns ce qu’ils refusaient aux « incapables », l’article suggère que nous en viendrions aujourd’hui progressivement à penser l’homme dans l’ordre de la conjonction, toujours fragile, toujours vulnérable, mais jamais non plus sans ressources, sans « capacités » qu’il s’agit alors d’éveiller, d’équiper. Cette hypothèse ouvre alors d’intéressantes perspectives pour contextualiser la spécificité de la sociologie pragmatique et son succès actuel, pour saisir la pertinence et les limites de son outillage conceptuel et méthodologique. Il se termine sur une réflexion quant à la manière de saisir les situations où les acteurs ne sont pas capables, évoquant alors deux voies empruntées par la sociologie pragmatique pour aborder cette question, une voie agonistique d’abord, une voie inquiète ensuite.Being capable and skilled : anthropological reading and pragmacticThe terms “competences” and “capacities” have occupied for a few years

An Organization-Based View of Strategy and an Integrative Framework of Strategic Management

OpenAIRE

Li, Xin

2017-01-01

Just like scholars distinguish two types of firm’s external environment, i.e., competitive and institutional, we make a distinction between two types of firm’s internal environment, i.e., resources and organization. Based on this distinction, we propose an organization-based view of strategy (OBV), not only as a label to unite various organization-related issues within the strategy field, but also as a fourth research paradigm to supplement to three existing paradigms, i.e., industry- or comp...

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization

Science.gov (United States)

Take, Kazumi; Mochida, Taisuke; Maki, Toshiyuki; Satomi, Yoshinori; Hirayama, Megumi; Nakakariya, Masanori; Amano, Nobuyuki; Adachi, Ryutaro; Sato, Kenjiro; Kitazaki, Tomoyuki; Takekawa, Shiro

2016-01-01

Monoacylglycerol O-acyltransferase 2 (MGAT2) catalyzes the synthesis of diacylglycerol (DG), a triacylglycerol precursor and potential peripheral target for novel anti-obesity therapeutics. High-throughput screening identified lead compounds with MGAT2 inhibitory activity. Through structural modification, a potent, selective, and orally bioavailable MGAT2 inhibitor, compound A (compA), was discovered. CompA dose-dependently inhibited postprandial increases in plasma triglyceride (TG) levels. Metabolic flux analysis revealed that compA inhibited triglyceride/diacylglycerol resynthesis in the small intestine and increased free fatty acid and acyl-carnitine with shorter acyl chains than originally labelled fatty acid. CompA decreased high-fat diet (HFD) intake in C57BL/6J mice. MGAT2-null mice showed a similar phenotype as compA-treated mice and compA did not suppress a food intake in MGAT2 KO mice, indicating that the anorectic effects were dependent on MGAT2 inhibition. Chronic administration of compA significantly prevented body weight gain and fat accumulation in mice fed HFD. MGAT2 inhibition by CompA under severe diabetes ameliorated hyperglycemia and fatty liver in HFD-streptozotocin (STZ)-treated mice. Homeostatic model assessments (HOMA-IR) revealed that compA treatment significantly improved insulin sensitivity. The proximal half of the small intestine displayed weight gain following compA treatment. A similar phenomenon has been observed in Roux-en-Y gastric bypass-treated animals and some studies have reported that this intestinal remodeling is essential to the anti-diabetic effects of bariatric surgery. These results clearly demonstrated that MGAT2 inhibition improved dyslipidemia, obesity, and diabetes, suggesting that compA is an effective therapeutic for obesity-related metabolic disorders. PMID:26938273

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization.

Directory of Open Access Journals (Sweden)

Kazumi Take

Full Text Available Monoacylglycerol O-acyltransferase 2 (MGAT2 catalyzes the synthesis of diacylglycerol (DG, a triacylglycerol precursor and potential peripheral target for novel anti-obesity therapeutics. High-throughput screening identified lead compounds with MGAT2 inhibitory activity. Through structural modification, a potent, selective, and orally bioavailable MGAT2 inhibitor, compound A (compA, was discovered. CompA dose-dependently inhibited postprandial increases in plasma triglyceride (TG levels. Metabolic flux analysis revealed that compA inhibited triglyceride/diacylglycerol resynthesis in the small intestine and increased free fatty acid and acyl-carnitine with shorter acyl chains than originally labelled fatty acid. CompA decreased high-fat diet (HFD intake in C57BL/6J mice. MGAT2-null mice showed a similar phenotype as compA-treated mice and compA did not suppress a food intake in MGAT2 KO mice, indicating that the anorectic effects were dependent on MGAT2 inhibition. Chronic administration of compA significantly prevented body weight gain and fat accumulation in mice fed HFD. MGAT2 inhibition by CompA under severe diabetes ameliorated hyperglycemia and fatty liver in HFD-streptozotocin (STZ-treated mice. Homeostatic model assessments (HOMA-IR revealed that compA treatment significantly improved insulin sensitivity. The proximal half of the small intestine displayed weight gain following compA treatment. A similar phenomenon has been observed in Roux-en-Y gastric bypass-treated animals and some studies have reported that this intestinal remodeling is essential to the anti-diabetic effects of bariatric surgery. These results clearly demonstrated that MGAT2 inhibition improved dyslipidemia, obesity, and diabetes, suggesting that compA is an effective therapeutic for obesity-related metabolic disorders.

Combining ability for maize grain yield and other agronomic ...

African Journals Online (AJOL)

STORAGESEVER

2009-06-03

Jun 3, 2009 ... the parameters except plant height, while specific combining ability (sca) and gca x year effects were significant only for grain yield. However, Tze Comp4 ... and days to flowering, with Hei 97 Tze Comp3 C4 combining very well with 3 parents (Acr 90 Pool 16-Dt,. Tze Comp4-Dmr Srbc2 and Tze Comp4 C2).

Evolutionary Medicine: The Ongoing Evolution of Human Physiology and Metabolism.

Science.gov (United States)

Rühli, Frank; van Schaik, Katherine; Henneberg, Maciej

2016-11-01

The field of evolutionary medicine uses evolutionary principles to understand changes in human anatomy and physiology that have occurred over time in response to environmental changes. Through this evolutionary-based approach, we can understand disease as a consequence of anatomical and physiological "trade-offs" that develop to facilitate survival and reproduction. We demonstrate how diachronic study of human anatomy and physiology is fundamental for an increased understanding of human health and disease. ©2016 Int. Union Physiol. Sci./Am. Physiol. Soc.

Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high-protein diet

OpenAIRE

Andriamihaja, Mireille; Davila-Gay, Anne-Marie; Eklou, Mamy; Petit, Nathalie; Delpal, Serge; Allek, Fadhila; Blais, Anne; Delteil, Corine; Tomé, Daniel; Blachier, Francois

2010-01-01

Andriamihaja M, Davila A, Eklou-Lawson M, Petit N, Delpal S, Allek F, Blais A, Delteil C, Tome D, Blachier F. Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high-protein diet. Am J Physiol Gastrointest Liver Physiol 299: G1030-G1037, 2010. First published August 5, 2010; doi: 10.1152/ajpgi.00149.2010.-Hyperproteic diets are used in human nutrition to obtain body weight reduction. Although increased protein ingestion results in an increased transf...

Développer et personnaliser les compétences info-communicationnelles des enseignants de français langue étrangère – un impératif face à une mutation des publics apprenant au Centre du Vietnam

Directory of Open Access Journals (Sweden)

HOANG Thi Thu Hanh

2016-12-01

Full Text Available Selon notre témoignage, le nombre d’apprenants de FLE au centre du Vietnam ne baisse pas mais les objectifs et les motivations ont changé et bien varié. Vu les débouchés francophones, il y a moins d’étudiants qui choisissent comme leur première option d’études universitaires les sciences du langage français et la didactique du FLE, mais de plus en plus nombreux sont ceux qui étudient le français comme un moyen de se professionnaliser et ou pour un objectif personnel (étudier ou faire un stage dans un pays francophone, consulter les documents en français, communiquer avec la clientèle francophone, participer à des réseaux sociaux, etc.. Cette situation témoigne d’une évolution des attentes où s’expriment un pouvoir d’action élargie et l’intégration dans un monde global largement numérisé. Se dessine ainsi progressivement une nouvelle voie pour l’apprentissage du FLE,résultat d’une convergence entre notre héritage culturel complexe et un milieu technique devenu un lieu de sociabilité sans précédent. Ces dernières années, plusieurs courants de pensée se sont intéressés à l’essor des TICE et à l’explosion des pratiques info-communicationnelles. Deux concepts dominent : l’information litéracy anglo-saxonne et nord-américaine et la culture de l’information francophone et européenne. La première, plus utilitariste, est centrée sur l’opérationnel dans une société de la connaissance ; la seconde propose de sortir d’une vision techniciste de la communication et vise le développement non seulement de compétences mais aussi de connaissances pour un monde ouvert. Compétences et connaissances que les enseignants doivent dorénavant maitriser avant de les transmettre.

Otimização da interface/interfase de compósitos termoplásticos de fibra de carbono/PPS pelo uso do poli(ácido âmico do tipo BTDA/DDS Optimization of the interface/interphase of carbon fiber/PPS thermoplastic composites using BTDA/DDS poly(amic acid

Directory of Open Access Journals (Sweden)

Liliana B. Nohara

2007-09-01

Full Text Available No presente trabalho duas técnicas de manufatura de compósitos termoplásticos estruturais são investigadas: a de moldagem por compressão a quente convencional e a de pré-impregnação via suspensão polimérica. A primeira consiste na impregnação do reforço via polímero fundido; enquanto que a segunda faz uso de suspensões poliméricas aquosas, onde a impregnação do reforço ocorre pelo contato deste com a suspensão aquosa de partículas da matriz polimérica. Esta técnica combina a matriz polimérica em pó com um outro polímero formador da suspensão, um poli(ácido âmico - PAA, sendo que os dois polímeros são simultaneamente depositados sobre o reforço, durante a impregnação. Este mesmo PAA, em uma segunda fase do processo, é convertido termicamente em uma poliimida (PI podendo formar uma região de interfase entre o reforço e a matriz polimérica. Este trabalho tem como objetivo a síntese e a caracterização de um PAA, à base de BTDA/DDS, e a avaliação de sua influência na formação da região de interfase em compósitos de poli(sulfeto de fenileno (PPS/fibras de carbono. Resultados de DSC e TG mostram o sucesso da síntese do PAA e de sua conversão em PI, esta com estabilidade térmica até 396 °C. O compósito processado pela técnica de suspensão polimérica apresenta resistência ao cisalhamento interlaminar (56,3 MPa 12,6% superior ao compósito obtido por moldagem por compressão a quente convencional (50,0 MPa. Estes resultados são confirmados por análises das superfícies de fratura, que mostram que o uso do PAA melhora a interfase do PPS/fibra de carbono.In the present work two different manufacturing techniques of thermoplastic composites are investigated: the conventional hot compression molding and the aqueous suspension prepregging. The first one involves the impregnation of the reinforcement with molten polymer; while the second one uses aqueous polymeric suspensions, where the reinforcement

Note de synthèse sur la sélection de niche spatiale et la compétition chez le jeune saumon Atlantique (Salmo salar et la truite commune (Salmo trutta en milieu lotique

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HEGGENES J.

1995-04-01

Full Text Available La sélection de l'habitat analysée à partir d'un ensemble de données récoltées sur des cours d'eau hétérogènes du point de vue spatio-temporel doit être interprétée en fonction du site et de l'échelle d'étude. La microniche spatiale fondamentale du juvénile de saumon Atlantique et de truite commune est caractérisée en été par une forte préférence pour une faible valeur de la vitesse de courant focale en raison d'une stratégie de gain énergétique basée essentiellement sur une prise alimentaire de la faune dérivante qui permet de maximiser les comportements de prise de position et d'attente du poisson. Cette microniche est également dépendante de la taille : chez le saumon, les plus gros parrs sont tolérants ; par contre chez la truite, une préférence accrue pour les habitats profonds est observée lorsqu'elles grossissent. La niche effective de la truite est relativement plus structurée par des valeurs élevées de la profondeur d'eau et des valeurs faibles de vitesse de courant lorsqu'elle est comparée à celle du saumon caractérisée par de faibles hauteurs d'eau et par des vitesses de courant élevées. Ces différences proviennent d'une plus grande tolérance du saumon pour les fortes vitesses de courant, combinée à un déplacement de la niche de cette espèce par suite d'une compétition avec la truite qui est plus agressive. Cette compétition interactive et interspécifique aboutit à une réduction de la niche spatiale effective chez le Saumon lorsque les paramètres vitesse de courant et profondeur d'eau sont pris en compte simultanément, et pas chez la truite.

Cartilage oligomeric matrix protein enhances matrix assembly during chondrogenesis of human mesenchymal stem cells.

Science.gov (United States)

Haleem-Smith, Hana; Calderon, Raul; Song, Yingjie; Tuan, Rocky S; Chen, Faye H

2012-04-01

Cartilage oligomeric matrix protein/thrombospondin-5 (COMP/TSP5) is an abundant cartilage extracellular matrix (ECM) protein that interacts with major cartilage ECM components, including aggrecan and collagens. To test our hypothesis that COMP/TSP5 functions in the assembly of the ECM during cartilage morphogenesis, we have employed mesenchymal stem cell (MSC) chondrogenesis in vitro as a model to examine the effects of COMP over-expression on neo-cartilage formation. Human bone marrow-derived MSCs were transfected with either full-length COMP cDNA or control plasmid, followed by chondrogenic induction in three-dimensional pellet or alginate hydrogel culture. MSC chondrogenesis and ECM production was estimated based on quantitation of sulfated glycosaminoglycan (sGAG) accumulation, immunohistochemistry of the presence and distribution of cartilage ECM proteins, and real-time RT-PCR analyis of mRNA expression of cartilage markers. Our results showed that COMP over-expression resulted in increased total sGAG content during the early phase of MSC chondrogenesis, and increased immuno-detectable levels of aggrecan and collagen type II in the ECM of COMP-transfected pellet and alginate cultures, indicating more abundant cartilaginous matrix. COMP transfection did not significantly increase the transcript levels of the early chondrogenic marker, Sox9, or aggrecan, suggesting that enhancement of MSC cartilage ECM was effected at post-transcriptional levels. These findings strongly suggest that COMP functions in mesenchymal chondrogenesis by enhancing cartilage ECM organization and assembly. The action of COMP is most likely mediated not via direct changes in cartilage matrix gene expression but via interactions of COMP with other cartilage ECM proteins, such as aggrecan and collagens, that result in enhanced assembly and retention.

CARTILAGE OLIGOMERIC MATRIX PROTEIN ENHANCES MATRIX ASSEMBLY DURING CHONDROGENESIS OF HUMAN MESENCHYMAL STEM CELLS

Science.gov (United States)

Haleem-Smith, Hana; Calderon, Raul; Song, Yingjie; Tuan, Rocky S.; Chen, Faye H.

2011-01-01

Cartilage oligomeric matrix protein/thrombospondin-5 (COMP/TSP5) is an abundant cartilage extracellular matrix (ECM) protein that interacts with major cartilage ECM components, including aggrecan and collagens. To test our hypothesis that COMP/TSP5 functions in the assembly of the ECM during cartilage morphogenesis, we have employed mesenchymal stem cell (MSC) chondrogenesis in vitro as a model to examine the effects of COMP over-expression on neo-cartilage formation. Human bone marrow-derived MSCs were transfected with either full-length COMP cDNA or control plasmid, followed by chondrogenic induction in three-dimensional pellet or alginate-hydrogel culture. MSC chondrogenesis and ECM production was estimated based on quantitation of sulfated glycosaminoglycan (sGAG) accumulation, immunohistochemistry of the presence and distribution of cartilage ECM proteins, and real-time RT-PCR analyis of mRNA expression of cartilage markers. Our results showed that COMP over-expression resulted in increased total sGAG content during the early phase of MSC chondrogenesis, and increased immuno-detectable levels of aggrecan and collagen type II in the ECM of COMP-transfected pellet and alginate cultures, indicating more abundant cartilaginous matrix. COMP transfection did not significantly increase the transcript levels of the early chondrogenic marker, Sox9, or aggrecan, suggesting that enhancement of MSC cartilage ECM was effected at post-transcriptional levels. These findings strongly suggest that COMP functions in mesenchymal chondrogenesis by enhancing cartilage ECM organization and assembly. The action of COMP is most likely mediated not via direct changes in cartilage matrix gene expression but via interactions of COMP with other cartilage ECM proteins, such as aggrecan and collagens, that result in enhanced assembly and retention. PMID:22095699

Interfacial stress affects rat alveolar type II cell signaling and gene expression

OpenAIRE

Hobi, Nina; Ravasio, Andrea; Haller, Thomas

2012-01-01

Previous work from our group (Ravasio A, Hobi N, Bertocchi C, Jesacher A, Dietl P, Haller T. Am J Physiol Cell Physiol 300: C1456–C1465, 2011.) showed that contact of alveolar epithelial type II cells with an air-liquid interface (IAL) leads to a paradoxical situation. It is a potential threat that can cause cell injury, but also a Ca2+-dependent stimulus for surfactant secretion. Both events can be explained by the impact of interfacial tensile forces on cellular structures. Here, the streng...

Estudo da cinética de decomposição de compósitos nanoestruturados de poli (sulfeto de fenileno reforçados com nanotubos de carbono

Directory of Open Access Journals (Sweden)

Bruno Ribeiro

2014-12-01

Full Text Available O objetivo deste trabalho consiste na obtenção de compósitos nanoestruturados de poli (sulfeto de fenileno (PPS reforçados com nanotubos de carbono de paredes múltiplas (MWCNT por meio da técnica de mistura em fusão, e posterior caracterização de suas propriedades morfológicas e térmicas. A análise por microscopia eletrônica de transmissão foi utilizada com o intuito de avaliar a qualidade da dispersão dos MWCNTs na matriz polimérica. A partir das curvas de termogravimetria obtidas, foi observado um aumento na temperatura máxima de degradação pela adição do nanoreforço na matriz polimérica. Além disso, o modelo matemático de Ozawa-Wall-Flynn foi utilizado com o intuito de determinar os parâmetros cinéticos de degradação. Os resultados mostraram um aumento de aproximadamente 25 ºC na temperatura máxima de degradação (Tmax quando uma pequena quantidade de MWCNT (0,5 wt % foi considerada. Este fato contribuiu para o aumento da estabilidade térmica do PPS.

Physiological Demands of Simulated Off-Road Cycling Competition

Directory of Open Access Journals (Sweden)

Gerhard Smekal, Serge P. von Duvillard, Maximilian Hörmandinger, Roland Moll, Mario Heller, Rochus Pokan, David W. Bacharach, Linda M. LeMura, Paul Arciero

2015-12-01

Full Text Available The purpose of the study was to measure the demands of off-road cycling via portable spirometry, leg-power output (PO, heart rate (HR and blood lactate (BLa concentration. Twenty-four male competitive cyclists (age: 29±7.2 yrs, height: 1.79 ± 0.05 m, body mass: 70.0 ± 4.9 kg, VO2peak: 64.9 ± 7.5 ml·kg-1·min-1 performed simulated mountain bike competitions (COMP and laboratory tests (LabT. From LabT, we determined maximal workload and first and second ventilatory thresholds (VT1, VT2. A high-performance athlete (HPA was used for comparison with three groups of subjects with different sport-specific performance levels. Load profiles of COMP were also investigated during uphill, flat and downhill cycling. During the COMP, athletes achieved a mean oxygen uptake (VO2COMP of 57.0 ± 6.8 ml·kg-1·min-1 vs. 71.1 ml·kg-1·min-1 for the HPA. The POCOMP was 2.66±0.43 W·kg-1 and 3.52 W·kg-1 for the HPA. POCOMP, VO2COMP and HRCOMP were compared to corresponding variables at the VT2 of LabT. LabT variables correlated with racing time (RTCOMP and POCOMP (p < 0.01 to <0.001; r-0.59 to -0.80. The VO2peak (LabT accounted for 65% of variance of a single COMP test. VO2COMP, POCOMP and also endurance variables measured from LabTs were found as important determinants for cross-country performance. The high average VO2COMP indicates that a high aerobic capacity is a prerequisite for successful COMP. Findings derived from respiratory gas measures during COMPs might be useful when designing mountain bike specific training.

¿Qué otras competencias debe tener el profesorado del alumnado inmigrante? (What Other Skills Should Have Teachers of Immigrant Students? (Quelles compétences doivent avoir les professeurs des élèves immigrés? (Quais outras competências deve ter o professorado de alunos imigrantes?

Directory of Open Access Journals (Sweden)

Hilario Murua-Cartón

2012-12-01

Full Text Available ResumenEste artículo de investigación se deriva del proyectoDesarrollo de competencias específicas del profesora- do y personal de apoyo para lograr la integración del alumnado inmigrante, iniciado en el curso 2008/09, sobre las competencias que debe presentar el profe- sorado que trabaja con alumnado inmigrante en las etapas de enseñanza infantil y primaria. Se planteó un cuestionario con 35 ítems referidos a Consciencia, Actitud, Conocimiento y Destreza y Habilidades. Tam- bién contó con preguntas abiertas sobre los niveles de satisfacción, expectativas de formación, situación personal... de los encuestados. En las conclusiones se observan la falta de preparación del profesorado para trabajar con alumnado inmigrante y su predisposición para la mejora de su práctica educativa.AbstractThis research article resulting from the project Development of speci- fic competences of teachers and su- pport staff to achieve the integration of immigrant students, started in the academic year 2008/09, on the skills required from the teachers working with immigrant students in stages of early childhood in Primary Education. It raised a questionnaire with 35 items related to: Awareness, Attitude, Skills and Knowledge and Skills. Also fea- tured open questions on satisfaction levels, training expectations, personal situation, of respondents. The conclu- sions noted the lack of preparation of teachers to work with immigrant stu- dents and their willingness to improve their educational practice.RésuméCet article de recherche découle du projet Développement de compéten- ces spécifiques des professeurs et du personnel d'appui pour réussir dans l'intégration des élèves immigrés; ce projet a commencé dans le cours 2008- 2009, par rapport aux compétences que les professeurs d’enseignement enfantin et primaire doivent avoir pour travailler avec des élèves immigrés. On a proposé un questionnaire avec tren- te-cinq 35 items référés �

Cardiovascular Physiology of Dinosaurs.

Science.gov (United States)

Seymour, Roger S

2016-11-01

Cardiovascular function in dinosaurs can be inferred from fossil evidence with knowledge of how metabolic rate, blood flow rate, blood pressure, and heart size are related to body size in living animals. Skeletal stature and nutrient foramen size in fossil femora provide direct evidence of a high arterial blood pressure, a large four-chambered heart, a high aerobic metabolic rate, and intense locomotion. But was the heart of a huge, long-necked sauropod dinosaur able to pump blood up 9 m to its head? ©2016 Int. Union Physiol. Sci./Am. Physiol. Soc.

RED BLOOD CELL AND WHOLE BLOOD GLUTATHIONE REDOX STATUS IN ENDURANCE-TRAINED MEN FOLLOWING A SKI MARATHON

Directory of Open Access Journals (Sweden)

Eve Unt

2008-09-01

Full Text Available The aim of the present study was to evaluate the changes in glutathione redox ratio (GSSG·GSH-1 in red blood cells (RBCs and whole blood in well-trained men following a ski marathon. 16 male subjects (27.0 ± 4.7 yrs, 1.81 ± 0.06 m, 77.6 ± 9.6 kg, VO2max 66.2 ± 5.7 ml·kg-1·min-1 were examined before the competition (pre- COMP, after the competition (post-COMP and during an 18-hour recovery period (RECOV. There was a slight decrease in reduced glutathione (GSH in blood and in RBCs in post-COMP. During RECOV, the GSH level in blood was reduced, the GSH level in RBCs was significantly elevated (a statistically significant difference as compared to the pre-COMP level. The post-COMP GSSG·GSH-1 in full blood did not increase significantly, but its increase was statistically significant during the 18-hour recovery period. During the post-COMP and RECOV, the GSSG·GSH-1 in RBCs slightly decreased in comparison with the pre-COMP. Vitamin C concentration in serum increased in post-COMP (49% vs. pre- COMP and decreased to the baseline level during RECOV. In conclusion, our data show that acute exercise slightly increases the GSSG·GSH-1 in whole blood, while GSSG·GSH-1 in RBCs significantly decreases. Thus, exercise-related changes in the non-enzymatic components of the glutathione system (GSSG and GSH in whole blood and RBCs are not identical

Modificação da rugosidade de fibras de carbono por método químico para aplicação em compósitos poliméricos

Directory of Open Access Journals (Sweden)

Burakowski Liliana

2001-01-01

Full Text Available O presente trabalho aborda o tratamento superficial de fibras de carbono por ácidos clorídrico e nítrico, visando o aumento controlado da rugosidade superficial da fibra e assim melhorar a ligação fibra/matriz no processamento de compósitos poliméricos reforçados com fibras longas. Foram utilizadas fibras de carbono com size, da empresa Toray. Essas foram tratadas com os ácidos clorídrico e nítrico, a 103°C, em concentrações de 35,5 % e 97 %, em massa, respectivamente, em tempos de exposição de 5, 10, 20, 30, 40 e 60 minutos. As fibras modificadas quimicamente foram caracterizadas por microscopia eletrônica de varredura e por ensaios mecânicos de tração e os dados foram tratados pelo método estatístico de Weibull. Os resultados mostram que os tratamentos empregados modificam a superfície da fibra e que períodos de tratamento superiores a 20 minutos as danificam, degradando de maneira significativa as suas propriedades mecânicas.

Resistência ao cisalhamento da colagem com compósitos utilizando potencializador de adesão Shear bond strength of composites using an adhesion booster

Directory of Open Access Journals (Sweden)

Edivaldo de Morais

2011-10-01

Full Text Available OBJETIVO: avaliar a resistência ao cisalhamento dos compósitos Transbond XT e Concise Ortodôntico utilizando o potencializador de adesão Ortho Primer. MÉTODOS: a amostra consistiu de 90 incisivos bovinos divididos em seis grupos (n=15. Todos os dentes receberam profilaxia com pedra-pomes e condicionamento do esmalte com ácido fosfórico. No Grupo I, utilizou-se Transbond XT de maneira convencional. O Grupo II foi semelhante ao I, porém, aplicou-se o Ortho Primer ao invés do XT Primer. No Grupo III, após condicionamento, o esmalte foi contaminado com saliva, aplicou-se o Ortho Primer e colagem com Transbond XT. No Grupo IV, utilizou-se o Concise Ortodôntico de maneira convencional. O Grupo V foi semelhante ao IV, porém, utilizou-se o Ortho Primer ao invés da resina fluida. No Grupo VI, após condicionamento, o esmalte foi contaminado com saliva, aplicou-se o Ortho Primer e colagem com Concise. Os corpos de prova foram armazenados em água destilada em estufa a 37ºC por 24h e submetidos ao ensaio de resistência ao cisalhamento. Os dados foram submetidos à ANOVA e ao teste de Tukey (5%. RESULTADOS: a resistência da colagem no Grupo IV foi estatisticamente superior à dos Grupos II, III e VI (p0,05. O Transbond XT e o Concise utilizados convencionalmente obtiveram os maiores valores adesivos. O Ortho Primer em esmalte seco atuou efetivamente como agente de união dos compósitos avaliados. Em esmalte contaminado, a colagem com Concise obteve baixa resistência adesiva.OBJECTIVE: The aim of this study was to evaluate the shear bond strength of the Transbond XT and Concise Orthodontics composites using the Ortho Primer adhesion booster. METHODS: The sample consisted of 90 bovine incisors divided in 6 groups (n=15. All teeth were submitted to prophylaxes with pumice stone and etching with phosphoric acid. In Group I the Transbond XT was used conventionally. Group II was similar to Group I, however, Ortho Primer was used instead of XT

Defense AT and L. Volume 44, Number 5

Science.gov (United States)

2015-10-01

priorities— all while integrating corporate branding initiatives. Smaller companies often do not enjoy the luxury of dedicated staffs, and the...future programs with examples of ways to increase cost- effectiveness , efficiency and success. Cost Capability Analysis Introduction to a Technique Frank...compe- titions and stressed “best value” source selections so we could take advantage of the most cost- effective radios available. Our “system” had a

The Firewall and Security of Information Systems

OpenAIRE

Radut Carmen; Albici Mihaela; Tenovici Cristina Otilia

2010-01-01

Information security is a broader concept which refers to ensuring the integrity, confidentiality and availability of information. The dynamics of information technology to induce new risks to which organizations must implement new measures of control. Technological development has been accompanied by security solutions, equipment manufacturers and applications including technical methods of protection performance. However, while in information technology change is exponential, the human comp...

Desenvolvimento de compósitos poliméricos baseados em polipropileno reciclado visando o uso como placas absorvedoras de energia solar

Directory of Open Access Journals (Sweden)

Leonardo Azevedo Massulo

2016-06-01

Full Text Available Devido à crescente demanda por energias sustentáveis, gestão de resíduos e o uso de materiais recicláveis, o presente trabalho objetivou o desenvolvimento de compósitos poliméricos de matriz de polipropileno reciclado visando o uso como placas absorvedoras de energia solar. Nessa matriz polimérica adicionou-se como fase dispersa um resíduo do tabaco (pó de fumo empregando teores de 10%, 15%, 20%, 25% e 30%, em massa. Além disso, estudou-se a adição de negro de fumo junto ao pó de fumo, utilizando teores de 6% e 10% de cada fase dispersa. As formulações foram misturadas em homogeneizador de laboratório, moídas em moinhos de facas e processadas por moldagem por compressão a 180°C, obtendo-se placas com dimensões de 400x400mm e espessura de 4 mm, as quais, foram caracterizadas e avaliadas em testes de absorção de calor, tração, flexão, dureza e densidade. Os resultados indicaram potencial de aplicação no sistema de aquecimento solar de água devido aos resultados de absorção térmica. Também, a utilização do negro de fumo como fase dispersa mostrou-se uma grande contribuição para as características mecânicas do material. Outro importante resultado diz respeito a possibilidade de se estar usando um polímero reciclado e um resíduo industrial gerado em grande quantidade, tal como é o pó de fumo, na produção das placas caracterizando assim um ganho ambiental.

Efeito da forma de processamento e do tratamento da fibra de curauá nas propriedades de compósitos com poliamida-6 Effect of the processing method and curauá fiber treatment on the properties of polyamide-6 composites

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Paulo A. Santos

2009-01-01

Full Text Available O interesse pela utilização de fibras vegetais como reforço para polímeros tem aumentado recentemente devido às suas vantagens ambientais e tecnológicas. Este trabalho avaliou o uso de fibras de Curauá para substituir a fibra de vidro em compósitos de poliamida-6. Teores de fibra de 0, 20, 30 ou 40 wt% e comprimento de 0,1 ou 10 mm foram analisados. Parte das fibras foi tratada com plasma de N2 ou lavados com solução de NaOH, para melhorar a adesão fibra/matriz. Compósitos com 20 wt% de fibra curta ou longa, sem ou com pré-tratamento, foram preparados em misturador interno e em duas extrusoras dupla-rosca, co-rotantes, interpenetrantes. Corpos de prova destas amostras moldados por injeção foram submetidos a testes de propriedades mecânicas (tração, flexão e impacto e térmicas (HDT. Observou-se que para as amostras com fibras sem tratamento processadas em extrusora, a não-secagem das matérias-primas melhorou a adesão interfacial fibra/matriz e que as propriedades mecânicas destes compósitos são melhores que a da PA-6 sem reforço, mas ainda não superam a PA-6 reforçada com fibra de vidro. Entretanto, sua menor densidade, sua resistência ao impacto, temperatura de deflexão térmica e contração de moldagem, comparáveis às da PA-6 reforçada com fibra de vidro, podem viabilizar a substituição desta em aplicações específicas. Este foi o primeiro trabalho a estudar o uso de fibra de curauá como reforço de um termoplástico de engenharia como a poliamida-6.The interest for the use of vegetal fibers as polymer reinforcement has recently increased because of their unique environmental and technological advantages. This work evaluated the use of Curauá fibers in polyamide-6 composites, aiming at glass fiber replacement. Fiber contents of 0, 20, 30 and 40 wt% and fiber lengths of 0.1 or 10 mm were analyzed. Part of short fibers were treated with N2 plasma, or washed with NaOH solution, to improve their adhesion to

High Performance Split-Stirling Cooler Program

Science.gov (United States)

1982-09-01

or crankcase subassembly includes the two drive cranks 1800 apart, the two motor bearings, the flywheel and target wheel . This assembly is dynamically...DISPLACER SEAL FRICTION REGENERATOR FLOW @ lOPSI E"I’ •’ REGENERATOR RUNOUT COMP. BRG. LUBRICATION "COMP. PISTON SEAL COMP. PISTON SEAL FRICTION INTER

Effect of light-activation methods and water storage on the flexural strength of two composite resins and a compomer Efeito da fotoativação e da armazenagem em água na resistência à flexão de duas resinas compostas e um compômero

Directory of Open Access Journals (Sweden)

Leonardo Eloy Rodrigues Filho

2006-04-01

Full Text Available The present study evaluated the flexural strength of three composite resins recommended for direct esthetic restorations: a polyacid modified composite (Dyract AP, a unimodal composite resin (Filtek Z250 and a hybrid composite resin (Point 4. The variation factors, apart from the type of composite resin, were the light activation method and the water storage period. The composite resins were light-cured in continuous mode (40 s, 500 mW/cm² or in ramp mode (0-800 mW/cm² for 10 s followed by 30 s at 800 mW/cm² and stored for 24 hours or 30 days in distilled water at 37°C. The data were analyzed by ANOVA and Tukey test for multiple comparisons (alpha = 0.05. The composite resin Z250 presented the highest mean flexural strength (166.74 MPa and Dyract AP presented the lowest one (129.76 MPa. The storage for 30 days decreased the flexural strength in ramp mode (24 h: 156.64 MPa; 30 days: 135.58 MPa. The light activation method alone did not lead to different flexural strength values.O presente estudo analisou a resistência à flexão de três compósitos recomendados para restaurações estéticas diretas: um compósito poliácido-modificado (Dyract AP, uma resina composta unimodal (Filtek Z250 e uma resina composta híbrida (Point 4. Os fatores de variação, além do tipo de compósito, foram o método de fotoativação e o período de armazenagem em água. Os materiais foram fotoativados continuamente por 40 s (500 mW/cm² ou com intensidade de luz crescente (0-800 mW/cm² por 10 s seguidos de 30 s a 800 mW/cm². Os períodos de armazenagem foram de 24 horas ou 30 dias em água destilada a 37°C. Os dados foram submetidos à análise de variância e ao teste de Tukey para comparações múltiplas (alfa = 0,05. A resina composta Z250 apresentou a maior média de resistência à flexão (166,74 MPa e a Dyract AP, a menor (129,76 MPa. A armazenagem por 30 dias diminuiu a resistência à flexão para o método de fotoativação crescente (24 h

Cartilage oligomeric matrix protein in patients with juvenile idiopathic arthritis: relation to growth and disease activity

DEFF Research Database (Denmark)

Bjørnhart, Birgitte; Juul, Anders; Nielsen, Susan

2009-01-01

OBJECTIVE: Cartilage oligomeric matrix protein (COMP) has been identified as a prognostic marker of progressive joint destruction in rheumatoid arthritis. In this population based study we evaluated associations between plasma concentrations of COMP, disease activity, and growth velocity...... in patients with recent-onset juvenile idiopathic arthritis (JIA). COMP levels in JIA and healthy children were compared with those in healthy adults. Plasma levels of insulin-like growth factor I (IGF-1), which has been associated with COMP expression and growth velocity, were studied in parallel. METHODS......: 87 patients with JIA entered the study, including oligoarticular JIA (n = 34), enthesitis-related arthritis (n = 8), polyarticular rheumatoid factor (RF)-positive JIA (n = 2), polyarticular RF-negative JIA (n = 27), systemic JIA (n = 6), and undifferentiated JIA (n = 10). Plasma levels of COMP were...

Aerodynamic performance of a hovering hawkmoth with flexible wings: a computational approach

OpenAIRE

Nakata, Toshiyuki; Liu, Hao

2011-01-01

Insect wings are deformable structures that change shape passively and dynamically owing to inertial and aerodynamic forces during flight. It is still unclear how the three-dimensional and passive change of wing kinematics owing to inherent wing flexibility contributes to unsteady aerodynamics and energetics in insect flapping flight. Here, we perform a systematic fluid-structure interaction based analysis on the aerodynamic performance of a hovering hawkmoth, Manduca, with an integrated comp...

Evaluation of Real-Time and Off-Line Performance of the Virtual Seismologist Earthquake Early Warning Algorithm in Switzerland

Science.gov (United States)

Behr, Yannik; Clinton, John; Cua, Georgia; Cauzzi, Carlo; Heimers, Stefan; Kästli, Philipp; Becker, Jan; Heaton, Thomas

2013-04-01

The Virtual Seismologist (VS) method is a Bayesian approach to regional network-based earthquake early warning (EEW) originally formulated by Cua and Heaton (2007). Implementation of VS into real-time EEW codes has been an on-going effort of the Swiss Seismological Service at ETH Zürich since 2006, with support from ETH Zürich, various European projects, and the United States Geological Survey (USGS). VS is one of three EEW algorithms that form the basis of the California Integrated Seismic Network (CISN) ShakeAlert system, a USGS-funded prototype end-to-end EEW system that could potentially be implemented in California. In Europe, VS is currently operating as a real-time test system in Switzerland. As part of the on-going EU project REAKT (Strategies and Tools for Real-Time Earthquake Risk Reduction), VS installations in southern Italy, western Greece, Istanbul, Romania, and Iceland are planned or underway. In Switzerland, VS has been running in real-time on stations monitored by the Swiss Seismological Service (including stations from Austria, France, Germany, and Italy) since 2010. While originally based on the Earthworm system it has recently been ported to the SeisComp3 system. Besides taking advantage of SeisComp3's picking and phase association capabilities it greatly simplifies the potential installation of VS at networks in particular those already running SeisComp3. We present the architecture of the new SeisComp3 based version and compare its results from off-line tests with the real-time performance of VS in Switzerland over the past two years. We further show that the empirical relationships used by VS to estimate magnitudes and ground motion, originally derived from southern California data, perform well in Switzerland.

3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase and NF-κB pathways.

Science.gov (United States)

Ali, Irshad; Manzoor, Zahid; Koo, Jung-Eun; Kim, Jung-Eun; Byeon, Sang-Hee; Yoo, Eun-Sook; Kang, Hee-Kyoung; Hyun, Jin-Won; Lee, Nam-Ho; Koh, Young-Sang

2017-12-01

Seaweeds are rich in bioactive compounds in the form of vitamins, phycobilins, polyphenols, carotenoids, phycocyanins and polysaccharides; many of these are known to have advantageous applications in human health. 3-Hydroxy-4,7-megastigmadien-9-one (comp) was isolated from Ulva pertusa (U. pertusa) Kjellman (Ulvaceae), which is a familiar edible green seaweed. This study evaluates the anti-inflammatory activity of comp in CpG DNA-stimulated bone marrow-derived dendritic cells (BMDCs). For evaluating the effect of comp on cytokines production, BMDCs were treated with doses of comp (0, 0.5, 1, 2, 5, 10, 25 and 50 μM) for 1 h before stimulation with CpG DNA (1 μM). Cytokine production was measured by ELISA. Western blotting was conducted for evaluating effect of comp (50 μM) on MAPKs and NF-κB pathways. Luciferase reporter gene assay was conducted for effect of comp (0, 5, 10 and 25 μM) on transcriptional activity of AP-1 and NF-κB. Comp exhibited strong inhibition of interleukin (IL)-12 p40, IL-6 and TNF-α cytokine production with IC 50 values of 6.02 ± 0.35, 27.14 ± 0.73, and 7.56 ± 0.21 μM, respectively. It blocked MAPKs and NF-κB pathways by inhibiting the phosphorylation of ERK1/2, JNK1/2, p38 and IκBα. In addition, it strongly inhibited the transcriptional activity of AP-1 and NF-κB with IC 50 values of 8.74 ± 0.31 and 12.08 ± 0.24 μM, respectively. Taken together, these data suggest that comp has a significant anti-inflammatory property and warrants further studies concerning the potential of comp for medicinal use.

Improving the use of principal component analysis to reduce physiological noise and motion artifacts to increase the sensitivity of task-based fMRI.

Science.gov (United States)

Soltysik, David A; Thomasson, David; Rajan, Sunder; Biassou, Nadia

2015-02-15

Functional magnetic resonance imaging (fMRI) time series are subject to corruption by many noise sources, especially physiological noise and motion. Researchers have developed many methods to reduce physiological noise, including RETROICOR, which retroactively removes cardiac and respiratory waveforms collected during the scan, and CompCor, which applies principal components analysis (PCA) to remove physiological noise components without any physiological monitoring during the scan. We developed four variants of the CompCor method. The optimized CompCor method applies PCA to time series in a noise mask, but orthogonalizes each component to the BOLD response waveform and uses an algorithm to determine a favorable number of components to use as "nuisance regressors." Whole brain component correction (WCompCor) is similar, except that it applies PCA to time-series throughout the whole brain. Low-pass component correction (LCompCor) identifies low-pass filtered components throughout the brain, while high-pass component correction (HCompCor) identifies high-pass filtered components. We compared the new methods with the original CompCor method by examining the resulting functional contrast-to-noise ratio (CNR), sensitivity, and specificity. (1) The optimized CompCor method increased the CNR and sensitivity compared to the original CompCor method and (2) the application of WCompCor yielded the best improvement in the CNR and sensitivity. The sensitivity of the optimized CompCor, WCompCor, and LCompCor methods exceeded that of the original CompCor method. However, regressing noise signals showed a paradoxical consequence of reducing specificity for all noise reduction methods attempted. Published by Elsevier B.V.

Value of Entheseal Ultrasonography and Serum Cartilage Oligomeric Matrix Protein in the Preclinical Diagnosis of Psoriatic Arthritis

Directory of Open Access Journals (Sweden)

Moataz Mohammed Samy Elbeblawy

2010-03-01

Full Text Available Objective: To evaluate the utility of entheseal ultrasonography and serum COMP in the preclinical diagnosis of psoriatic arthritis. Methods: 60 psoriatic patients were divided into: 30 patients with psoriasis (group I and 30 patients with psoriatic arthritis as control (group II. They underwent independent clinical and ultrasonographic examination of both lower limbs at the calcaneal insertions of Achilles tendons. Psoriatic arthritis disease activity and severity was assessed by modified DAS28 and Steinbrockers scores. Serum levels of COMP were measured for all patients by ELISA. Results: On clinical examination, no entheseal abnormalities were detected in group I while they were present in 23.3% of group II with statistically significant difference between them (P 0.05. Serum COMP were significantly elevated in group I and II with no statistically significant difference between them (mean ± SD 5.9 ± 3 and 6.8 ± 12 respectively, P > 0.05. Entheseal ultrasound was more specific (67% while serum COMP was more sensitive (87% in the preclinical diagnosis of psoriatic arthritis. Serum COMP levels were significantly correlated with CRP in both groups and with DAS28 and Steinbrockers scores in group II (P < 0.01. Conclusion: Entheseal ultrasonography and serum COMP levels may be used complementary to each other for preclinical diagnosis of psoriatic arthritis. Serum COMP seems to be promising prognostic marker for psoriatic arthritis patients.

Analytical Role of Corporate Strategy in Growth and Expansion of Unilever Pakistan

OpenAIRE

Hassan Abbas

2018-01-01

The corporate strategy plays an integral role in providing business entities with a market direction. The formulation and implementation of corporate strategy aids in providing businesses with abilities and capabilities so as to maintain and develop adequate pace with the consistently changing business environment, aids in the development of a strategic vision and focus on overall business goals and objectives, strengthens decision making and most importantly helps in the provision of a compe...

Nurse competencies for health promotion in the mental health context

OpenAIRE

Aguiar,Maria Isis Freire de; Lima,Hélder de Pádua; Braga,Violante Augusta Batista; Aquino,Priscila de Souza; Pinheiro,Ana Karina Bezerra; Ximenes,Lorena Barbosa

2012-01-01

OBJECTIVE: To identify the competencies of nurses to health promotion in psychiatric and mental health context. METHODS: Integrative review of literature performed through search using the keywords: "mental health" and "professional competence", in the databases SciELO, LILACS, CINAHL, PubMed, Scopus and Cochrane, in the period of 2003 to 2011. 215 studies were identified, of these, six followed the inclusion criteria. RESULTS: Based on the National Panel for Psychiatric Mental Health NP Comp...

Obesity and Cardiometabolic Defects in Heart Failure Pathology.

Science.gov (United States)

Halade, Ganesh V; Kain, Vasundhara

2017-09-12

Obesity is a major global epidemic that sets the stage for diverse multiple pathologies, including cardiovascular disease. The obesity-related low-grade chronic inflamed milieu is more pronounced in aging and responsive to cardiac dysfunction in heart failure pathology. Metabolic dysregulation of obesity integrates with immune reservoir in spleen and kidney network. Therefore, an integrative systems biology approach is necessary to delay progressive cardiac alternations. The purpose of this comprehensive review is to largely discuss the impact of obesity on the cardiovascular pathobiology in the context of problems and challenges, with major emphasis on the diversified models, and to study cardiac remodeling in obesity. The information in this article is immensely helpful in teaching advanced undergraduate, graduate, and medical students about the advancement and impact of obesity on cardiovascular health. © 2017 American Physiological Society. Compr Physiol 7:1463-1477, 2017. Copyright © 2017 John Wiley & Sons, Inc.

Comptia Network+ review guide exam N10-006

CERN Document Server

Ferguson, Bill

2015-01-01

Be prepared for the Network+ exam CompTIA Network+ Review Guide is your ideal study companion for preparing for the CompTIA Network+ exam (N10-006). This concise review is the perfect companion to the CompTIA Network+ Study Guide and the CompTIA Network+ Deluxe Study Guide, with full exam coverage organized by objective for quick review and reinforcement of key topics. Each of the book's five parts is devoted to a specific domain area of the exam, providing a focused review to bolster areas of weak understanding. You get access to the Sybex test engine, which includes two bonus practice tests

Tendências tecnológicas do uso do sisal em compósitos a partir da prospecção em documentos de patentes

Directory of Open Access Journals (Sweden)

Felipe Scopel

2013-01-01

Full Text Available As fibras naturais têm sido pesquisadas e empregadas de maneira crescente no desenvolvimento de produtos com sustentabilidade econômica, social e ambiental, sendo o sisal uma das mais importantes para o Brasil, pela sua posição de liderança na produção mundial. O presente artigo analisa a evolução temporal e o interesse das empresas e instituições em tecnologias associadas ao sisal, a partir de informações e indicadores extraídos de documentos de patentes no período de 1960 a 2009. Foi verificado o crescente patenteamento associado ao sisal em áreas de química, ciência dos materiais e dos polímeros, com destaque para o reforço do de compósitos plásticos. Além do crescente número de patentes, houve também um expressivo aumento do número de empresas e instituições titulares das patentes, o que reflete a possível desconcentração do mercado nesse crescimento do interesse pelas tecnologias associadas ao sisal. O Brasil, apesar da sua proeminência na produção do sisal, possui pequena presença no patenteamento mundial. Também foi verificada a importância da análise de patentes para o acompanhamento da evolução das tecnologias e interesses, pela disponibilidade de informações públicas que podem ser transformadas em indicadores úteis para análise de tecnologia e mercado associados ao sisal ou a outras áreas tecnológicas.

Rev-erbα and the circadian transcriptional regulation of metabolism

DEFF Research Database (Denmark)

Gerhart-Hines, Z.; Lazar, M. A.

2015-01-01

The circadian clock orchestrates the coordinated rhythmicity of numerous metabolic pathways to anticipate daily and seasonal changes in energy demand. This vital physiol. function is controlled by a set of individual clock components that are present in each cell of the body, and regulate each ot...... between circadian rhythm and tissue-specific biol. networks and its relevance to organismal physiology.......The circadian clock orchestrates the coordinated rhythmicity of numerous metabolic pathways to anticipate daily and seasonal changes in energy demand. This vital physiol. function is controlled by a set of individual clock components that are present in each cell of the body, and regulate each...

Compósitos de cimento - borracha de pneus: efeito da escória nas propriedades Tire rubber-cement composites: effect of slag on properties

Directory of Open Access Journals (Sweden)

N. Segre

2006-12-01

Full Text Available Compósitos de cimento-borracha de pneus preparados com cimentos tipo I e contendo adições de três diferentes escórias foram estudados. Resistência à flexão, absorção de água e resistência ao ataque ácido foram investigadas. Um decréscimo no módulo de ruptura (MOR foi observado para todos os corpos de prova contendo borracha, quando comparados com os corpos de prova sem borracha (controles. Para as pastas controle e com borracha e argamassas controle, preparadas com cimento com escória, o MOR aumenta com o aumento da atividade hidráulica da escória utilizada, até valores indistinguíveis dos obtidos para as argamassas e pastas preparadas com cimento tipo I. Argamassas com borracha apresentaram valores de MOR independentes do cimento utilizado. Uma redução na sorção de água é observada para corpos de prova controle e contendo borracha, preparados com todos os cimentos contendo adição de escória, quando comparados com os corpos de prova preparados com cimento tipo I. Para corpos de prova de argamassa com borracha, quanto mais baixa é a basicidade da escória, menor é a sorção de água dos compósitos. Estes resultados indicam baixa porosidade e consequentemente uma melhor adesão entre a borracha e a matriz de cimento nestes corpos de prova. Além disso, uma velocidade menor de sorção de água é observada para os corpos de prova com borracha, com destaque para os corpos de prova com cimento que contém a escória menos básica, quando comparados com os controles. Resultados de ataque ácido aos corpos e prova de argamassas, preparadas com os cimentos contendo adição de escória, mostram que a susceptibilidade dos corpos de prova frente à degradação por ácido é governada não somente por aspectos microestruturais, como porosidade e permeabilidade, mas também por aspectos químicos, como diferenças na quantidade de álcalis presentes nas escórias ou quantidade de escória não reagida nos corpos de prova

Flow and solute transport in backfilled tunnel and collapsed backfill - possible extension of Comp32

International Nuclear Information System (INIS)

Neretnieks, Ivars

2006-09-01

considerably and in fact is nearly as effective as if the same water flowrate were to flow in the pores of the backfill and be in direct contact with the sorbing backfill. A collapsed region at the top of the tunnel thus does not have a detrimental effect on the nuclide movement. In fact, by forming a high conductivity channel on top of the backfill most or practically all water that flows in the tunnels will move there. As a consequence there will be much less flow in the backfill itself. The nuclide will have to diffuse from the canister up to the ceiling of the tunnel before it can move along the tunnel. Numerical computations are also used to simulate the combined effects of diffusion from a damage at the top of a canister up to and into the backfill and further transport along the tunnel. An intact backfill as well as a collapsed backfill are simulated. The results confirm the analysis based on the simpler models. The so called Near Field Model Comp32 used in SKB performance assessment modeling could directly be extended to account for flow along the tunnel with or without a collapsed part

Flow and solute transport in backfilled tunnel and collapsed backfill - possible extension of Comp32

Energy Technology Data Exchange (ETDEWEB)

Neretnieks, Ivars [Royal Inst. of Technology, Stockholm (Sweden). Dept. of Chemical Engineering and Technology

2006-09-15

migration considerably and in fact is nearly as effective as if the same water flowrate were to flow in the pores of the backfill and be in direct contact with the sorbing backfill. A collapsed region at the top of the tunnel thus does not have a detrimental effect on the nuclide movement. In fact, by forming a high conductivity channel on top of the backfill most or practically all water that flows in the tunnels will move there. As a consequence there will be much less flow in the backfill itself. The nuclide will have to diffuse from the canister up to the ceiling of the tunnel before it can move along the tunnel. Numerical computations are also used to simulate the combined effects of diffusion from a damage at the top of a canister up to and into the backfill and further transport along the tunnel. An intact backfill as well as a collapsed backfill are simulated. The results confirm the analysis based on the simpler models. The so called Near Field Model Comp32 used in SKB performance assessment modeling could directly be extended to account for flow along the tunnel with or without a collapsed part.

Improvement of reduced serum cartilage oligomeric matrix protein levels in systemic juvenile idiopathic arthritis patients treated with the anti-interleukin-6 receptor monoclonal antibody tocilizumab.

Science.gov (United States)

Nakajima, Shoko; Naruto, Takuya; Miyamae, Takako; Imagawa, Tomoyuki; Mori, Masaaki; Nishimaki, Shigeru; Yokota, Shumpei

2009-01-01

In this study, we determined serum cartilage oligomeric matrix protein (COMP) levels in systemic juvenile idiopathic arthritis (sJIA) patients during both the active and the remission phases to investigate how the growth cartilage turnover changed under tocilizumab treatment. Specimens were collected from 201 healthy children under 16 years of age with no growth impairment, and paired sera were collected from 11 sJIA patients treated with tocilizumab. Disease activity was assessed from white blood cell count, erythrocyte sedimentation rate, C-reactive protein, and ferritin, and the COMP concentration was determined by sandwich enzyme-linked immunosorbent assay. Serum COMP concentrations were found independent of age, and the mean value in healthy children was 17.74+/-5.6 U/L. The mean serum COMP in sJIA patients during the active phase was 10.75+/-3.9 U/L, lower than that of healthy children. The mean serum COMP in the remission phase (14.89+/-3.9 U/L) was significantly higher than that in the active period (P<0.05). These results suggested that in sJIA patients, a reduced serum COMP concentration is a useful marker of active disease and growth impairment, and that the growth cartilage turnover suppressed during the active phase is improved in the remission phase under tocilizumab treatment.

Coffee seeds isotopic composition as a potential proxy to evaluate Minas Gerais, Brazil seasonal variations during seed maturation

Science.gov (United States)

Rodrigues, Carla; Maia, Rodrigo; Brunner, Marion; Carvalho, Eduardo; Prohaska, Thomas; Máguas, Cristina

2010-05-01

between plant physiology and local climate variations as well as the particularly soil geology. De Castro, R. D., Marraccini, P., 2006. Cytology, biochemistry and molecular changes during coffee fruit development. Braz. J. Plant Physiol., 18(1) : 175 - 199. Rodrigues, C. I., Maia, R. Miranda, M., Ribeirinho, M., Nogueira, J. M. F., Máguas, C., 2009. Stable isotope analysis for green coffee bean: A possible method for geographical origin discrimination. J. Food Comp. Anal. 22, 463-471 Rodrigues, C., Prohaska, T., Máguas, C., 2009. Strontium and Oxygen Isotope Fingerprinting of Green Coffee Beans and its Potential to Proof Authenticity of Coffee. Food Chem. (submitted). Acknowledgements Carla Rodrigues wishes to thank Fundação para a Ciência e a Tecnologia for a grant (SFRH/BD/28354/2006). Financial support by the Austrian Science Foundation (FWF START grant 267 N11) is highly acknowledged.

The EPA CompTox Chemistry Dashboard - an online resource for environmental chemists (ACS Spring Meeting)

Science.gov (United States)

The U.S. Environmental Protection Agency (EPA) Computational Toxicology Program integrates advances in biology, chemistry, and computer science to help prioritize chemicals for further research based on potential human health risks. This work involves computational and data drive...

Comp23/Nuctran user's guide. Proper version 1.1.6

International Nuclear Information System (INIS)

Romero, L.; Thompson, A.; Moreno, L.; Neretnieks, I.; Widen, H.; Boghammar, A.

1999-10-01

NUCTRAN is a fast multiple path model that calculates nuclide transport in the near field of a repository as occurring through a network of resistances and capacitances coupled together like an electrical circuit network. The model, which is a very coarsely discretized integrated finite difference model, was devised to be very fast and compact by embedding analytical solutions at sensitive zones. The code allows the user to simultaneously consider a multitude of pathways by which the nuclides are transported by diffusion to the flowing water in fractures surrounding the barrier system. The nuclide dissolution may be calculated using two approaches, a solubility limit approach or a congruent dissolution approach. The conceptual model used in NUCTRAN can be represented by three bodies. The bodies are the source, the barrier system, and the sinks. The source is defined as a well-mixed compartment. The barrier system is the physical medium by which the nuclides migrate to reach the sinks located in the surrounding system or outside of the region considered as the barrier system. The sinks, considered as recipients where the water flows, are fully defined by a local equivalent flow rate. The purpose of this document is to assist the user in managing problems with NUCTRAN. An overview of the theory, numerical method, and the code designed to solve the problem are presented. Finally, an example is handled in detail

Effect of post-thaw addition of seminal plasma on motility, viability and chromatin integrity of cryopreserved donkey jack (Equus asinus) spermatozoa.

Science.gov (United States)

Sabatini, C; Mari, G; Mislei, B; Love, Cc; Panzani, D; Camillo, F; Rota, A

2014-12-01

Pregnancy rates in donkeys after artificial insemination with cryopreserved semen are still low, compared to the horse species. Addition of autologous seminal plasma to frozen-thawed semen appeared to improve pregnancy rates. The aims of this study were to evaluate (1) sperm motility and plasma membrane integrity after thawing (T0) and after one and 2 h (T1 and T2) of post-thaw incubation in either 0% (SP0) or 70% (SP70) autologous seminal plasma and (2) sperm motility, plasma membrane integrity and DNA quality (%COMP-αt) after thawing (T0) and after 2 and 4 h (T2 and T4) of post-thaw incubation in either 0% (SP0), 5% (SP5) or 20% (SP20) homologous seminal plasma. In experiment 1, seminal plasma decreased total and progressive sperm motility and plasma membrane intact spermatozoa immediately after dilution and at all following time points (p < 0.05). In experiment 2, total and progressive motility did not differ between treatments immediately after dilution and between SP0 and SP5 at T2, while they were lower in both SP5 and SP20 than in SP0 at T4. Plasma membrane intact sperm cells did not differ between SP0 and SP5 and were lower in SP20 at all time points. DNA quality was not affected by treatment immediately after dilution and was significantly worse for SP20 after 4 h of incubation (p < 0.05). The post-thaw addition of seminal plasma at the tested concentrations did not improve donkey frozen semen characteristics in vitro over time. © 2014 Blackwell Verlag GmbH.

Mathematical foundations of the dendritic growth models.

Science.gov (United States)

Villacorta, José A; Castro, Jorge; Negredo, Pilar; Avendaño, Carlos

2007-11-01

At present two growth models describe successfully the distribution of size and topological complexity in populations of dendritic trees with considerable accuracy and simplicity, the BE model (Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997) and the S model (Van Pelt and Verwer in Bull. Math. Biol. 48:197-211, 1986). This paper discusses the mathematical basis of these models and analyzes quantitatively the relationship between the BE model and the S model assumed in the literature by developing a new explicit equation describing the BES model (a dendritic growth model integrating the features of both preceding models; Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997). In numerous studies it is implicitly presupposed that the S model is conditionally linked to the BE model (Granato and Van Pelt in Brain Res. Dev. Brain Res. 142:223-227, 2003; Uylings and Van Pelt in Network 13:397-414, 2002; Van Pelt, Dityatev and Uylings in J. Comp. Neurol. 387:325-340, 1997; Van Pelt and Schierwagen in Math. Biosci. 188:147-155, 2004; Van Pelt and Uylings in Network. 13:261-281, 2002; Van Pelt, Van Ooyen and Uylings in Modeling Dendritic Geometry and the Development of Nerve Connections, pp 179, 2000). In this paper we prove the non-exactness of this assumption, quantify involved errors and determine the conditions under which the BE and S models can be separately used instead of the BES model, which is more exact but considerably more difficult to apply. This study leads to a novel expression describing the BE model in an analytical closed form, much more efficient than the traditional iterative equation (Van Pelt et al. in J. Comp. Neurol. 387:325-340, 1997) in many neuronal classes. Finally we propose a new algorithm in order to obtain the values of the parameters of the BE model when this growth model is matched to experimental data, and discuss its advantages and improvements over the more commonly used procedures.

Fractografia de compósito estrutural aeronáutico submetido à caracterização de tenacidade à fratura interlaminar em modo I Fractography of aeronautical composite structures submitted to mode I interlaminar fracture toughness characterization

Directory of Open Access Journals (Sweden)

Geraldo Maurício Cândido

2012-01-01

Full Text Available Muitos componentes das modernas aeronaves estão sendo manufaturados em compósitos poliméricos. Laminados de resina epóxi modificada reforçada com fibras de carbono contínuas são empregados em estruturas primárias e secundárias para reduzir o peso e melhorar o desempenho operacional. Porém, se ocorrer uma falha circunstancial, o processo de fratura desses laminados é complexo e pode envolver mecanismos de danos interlaminares. A delaminação é a descontinuidade interlaminar que pode se propagar de forma catastrófica com a aplicação de cargas mecânicas. O ensaio de corpos de prova denominado de Double Cantilever Beam (DCB é o método mais utilizado para determinar a tenacidade à fratura em Modo I de compósitos estruturais. Neste trabalho, amostras preparadas de um laminado de tecido bidirecional, estilo plain weave, foram submetidas ao carregamento estático de delaminação em Modo I, à temperatura ambiente. A análise fractográfica das superfícies delaminadas foi realizada por microscopia eletrônica de varredura. Os resultados mostram que o processo de fratura se inicia nas bolsas de resina após um inserto de Teflon® e se propaga ao longo das regiões ricas em resina posicionadas nos interstícios de entrelaçamento das mechas da trama e da urdidura. Os principais aspectos fractográficos revelados são identificados, documentados e discutidos neste trabalho.Many components of modern aircrafts are now manufactured from polymer composites. Reinforced laminates with continuous carbon fibers and modified epoxy resin are employed in primary and secondary structures to reduce weight and improve the aircraft performance. However, if a circumstantial failure happens, the complex fracture process of the laminates may involve interlaminar damage mechanisms. The delamination is the interlaminar discontinuity which may propagate catastrophically with the application of mechanical loads. The Double Cantilever Beam (DCB is the most

Xeon Phi - A comparison between the newly introduced MIC architecture and a standard CPU through three types of problems.

OpenAIRE

Kristiansen, Joakim

2016-01-01

As Moore s law continues, processors keep getting more cores packed together on the chip. This thesis is an empirical study of the rather newly introduced Intel Many Integrated Core (IMIC) architecture found in the Intel Xeon Phi. With roughly 60 cores connected by a high performance on-die interconnect, the Intel Xeon Phi makes an interesting candidate for High Performance Computing. By digging into parallel algorithms solving three well known problems, our goal is to optimize, test and comp...

Mathematics++ selected topics beyond the basic courses

CERN Document Server

Kantor, Ida; Šámal, Robert

2015-01-01

Mathematics++ is a concise introduction to six selected areas of 20th century mathematics providing numerous modern mathematical tools used in contemporary research in computer science, engineering, and other fields. The areas are: measure theory, high-dimensional geometry, Fourier analysis, representations of groups, multivariate polynomials, and topology. For each of the areas, the authors introduce basic notions, examples, and results. The presentation is clear and accessible, stressing intuitive understanding, and it includes carefully selected exercises as an integral part. Theory is comp

Perspectives de la rupture quantique 2025-2050 : vers une interprétation quantique du Knowledge Marketing et une NBIC(Q)S Convergence

OpenAIRE

CURBATOV, Oleg

2015-01-01

International audience; Perspectives de la rupture quantique 2025-2050 : vers une interprétation quantique du Knowledge Marketing et une NBIC(Q)S Convergence ----------------par Oleg Curbatov, chapitre d'ouvrage : « Knowledge Marketing : être compétent dans une économie compétitive », Impressum, 2015 ---------------------------- Les recherches qui ont été porté à la fois sur la connaissance du consommateur, la compétence du client et les situations de co-création, nous ont permis d " explorer...

Automatic calculation of massive two-loop self-energies with XLOOPS

International Nuclear Information System (INIS)

Franzkowski, J.

1997-01-01

Within the program package XLOOPS it is possible to calculate self-energies up to the two-loop level for arbitrary massive particles. The program package -written in MAPLE (Char et al., Maple V Language Reference Manual (Springer, 1991); Char et al., Maple V Library Reference Manual (Springer, 1991)) - is designed to deal with the full tensor structure of the occurring integrals. This means that applications are not restricted to those cases where the reduction to scalars via equivalence theorem is allowed. The algorithms handle two-loop integrals analytically if this is possible. For those topologies where no analytic result for the general mass case is available, the diagrams are reduced to integral representations which encounter at most at two-fold integration. These integral representations are numerically stable and can be performed easily using VEGAS (Lepage, J. Comp. Phys. 27 (1978) 192; Lepage, Cornell Univ. Preprint CLNS-80/447 (1980)). (orig.)

Hvad enhver kordreng skal kunne. Betragtning af motetten Ut Phebi radiis af Josquin Desprez

DEFF Research Database (Denmark)

Christoffersen, Peter Woetmann

2003-01-01

Josquin Desprez, Ut Phebi radiis, motet, prayer mode, hexachord, Ockeghem, Brumel, Isaac, Compère, sound, udtryk......Josquin Desprez, Ut Phebi radiis, motet, prayer mode, hexachord, Ockeghem, Brumel, Isaac, Compère, sound, udtryk...

Influência da Velocidade de Rotação do Rebite na Microestrutura e no Desempenho Mecânico de Juntas de Compósito Termofixo Rebitadas por Fricção

Directory of Open Access Journals (Sweden)

Natascha Zocoller Borba

2016-03-01

Full Text Available Resumo A Rebitagem por Fricção tem se demonstrado como alternativa para união de perfis de compósito termofixo aplicados na construção civil, frente às necessidades atuais por tecnologias eficientes de união de estruturas multimateriais. Nesse processo, a extremidade de um rebite metálico é plastificada e forjada dentro de um componente polimérico, via calor friccional. Sua viabilidade técnica já foi demonstrada para juntas de Ti-6Al-4V/poliéster termofixo reforçado com fibra de vidro. Este artigo tem como objetivo complementar esse estudo através da análise do efeito da velocidade de rotação do rebite na temperatura do processo, microestrutura e propriedades mecânicas locais e globais das juntas. Foram fabricadas juntas com dois níveis de velocidade de rotação: 9000 rpm e 10000 rpm (os demais parâmetros foram mantidos constantes. Temperaturas do processo (655-765 °C superiores em 96% da temperatura de início de decomposição da matriz de poliéster (370 °C foram atingidas, desencadeando degradação polimérica acentuada na região de união. O aumento da velocidade de rotação e, portanto, do aporte térmico, não contribuiu estatisticamente para o aumento na profundidade de penetração e na largura da extremidade deformada do rebite. Porém, a extensão da área polimérica degradada aumentou em 47%, a qual resultou em redução proporcional de 50% da resistência à tração das juntas (de 4,0 ± 1,2 kN para 2,0 ± 0,7 kN. Adicionalmente, mapas de microdureza no rebite evidenciaram possíveis transformações de fase da liga que favoreceram seu endurecimento, com o aumento da velocidade de rotação. Contudo, nenhuma correlação pôde ser evidenciada entre a dureza e o desempenho mecânico das juntas sob tração, já que as amostras falharam majoritariamente por arrancamento completo do rebite da placa de compósito. Portanto, no desenvolvimento de juntas rebitadas por fricção de Ti-6Al-4V/ poli

75 FR 15736 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

Science.gov (United States)

2010-03-30

... Kansas City, MO....... 02/22/10 02/10/10 Pharmaceuticals (Comp). 73543 Bumble Bee Foods, LLC (Comp..., Siemens World Boise, ID 02/24/10 02/23/10 Travel (Wkrs). 73561 Musashi Auto Parts (State).. Battle Creek...

Changes in Cartilage Biomarker Levels During a Transcontinental Multistage Footrace Over 4486 km.

Science.gov (United States)

Mündermann, Annegret; Klenk, Christopher; Billich, Christian; Nüesch, Corina; Pagenstert, Geert; Schmidt-Trucksäss, Arno; Schütz, Uwe

2017-09-01

Cartilage turnover and load-induced tissue changes are frequently assessed by quantifying concentrations of cartilage biomarkers in serum. To date, information on the effects of ultramarathon running on articular cartilage is scarce. Serum concentrations of cartilage oligomeric matrix protein (COMP), matrix metalloproteinase (MMP)-1, MMP-3, MMP-9, COL2-3/4C long mono (C2C), procollagen type II C-terminal propeptide (CPII), and C2C:CPII will increase throughout a multistage ultramarathon. Descriptive laboratory study. Blood samples were collected from 36 runners (4 female; mean age, 49.0 ± 10.7 years; mean body mass index, 23.1 ± 2.3 kg/m 2 [start] and 21.4 ± 1.9 kg/m 2 [finish]) before (t 0 ) and during (t 1 : 1002 km; t 2 : 2132 km; t 3 : 3234 km; t 4 : 4039 km) a 4486-km multistage ultramarathon. Serum COMP, MMP-1, MMP-3, MMP-9, C2C, and CPII levels were assessed using commercial enzyme-linked immunosorbent assays. Linear mixed models were used to detect significant changes in serum biomarker levels over time with the time-varying covariates of body weight, running speed, and daily running time. Serum concentrations of COMP, MMP-9, and MMP-3 changed significantly throughout the multistage ultramarathon. On average, concentrations increased during the first measurement interval (MI1: t 1 -t 0 ) by 22.5% for COMP (95% CI, 0.29-0.71 ng/mL), 22.3% for MMP-3 (95% CI, 0.24-15.37 ng/mL), and 95.6% for MMP-9 (95% CI, 81.7-414.5 ng/mL) and remained stable throughout MI2, MI3, and MI4. Serum concentrations of MMP-1, C2C, CPII, and C2C:CPII did not change significantly throughout the multistage ultramarathon. Changes in MMP-3 were statistically associated with changes in COMP throughout the ultramarathon race (MMP-3: Wald Z = 3.476, P = .001). Elevated COMP levels indicate increased COMP turnover in response to extreme running, and the association between load-induced changes in MMP-3 and changes in COMP suggests the possibility that MMP-3 may be involved in the

Effects of nitrate and phosphate supply on chromophoric and fluorescent dissolved organic matter in the Eastern Tropical North Atlantic: a mesocosm study

Science.gov (United States)

Loginova, A. N.; Borchard, C.; Meyer, J.; Hauss, H.; Kiko, R.; Engel, A.

2015-12-01

In open-ocean regions, as is the Eastern Tropical North Atlantic (ETNA), pelagic production is the main source of dissolved organic matter (DOM) and is affected by dissolved inorganic nitrogen (DIN) and phosphorus (DIP) concentrations. Changes in pelagic production under nutrient amendments were shown to also modify DOM quantity and quality. However, little information is available about the effects of nutrient variability on chromophoric (CDOM) and fluorescent (FDOM) DOM dynamics. Here we present results from two mesocosm experiments ("Varied P" and "Varied N") conducted with a natural plankton community from the ETNA, where the effects of DIP and DIN supply on DOM optical properties were studied. CDOM accumulated proportionally to phytoplankton biomass during the experiments. Spectral slope (S) decreased over time indicating accumulation of high molecular weight DOM. In Varied N, an additional CDOM portion, as a result of bacterial DOM reworking, was determined. It increased the CDOM fraction in DOC proportionally to the supplied DIN. The humic-like FDOM component (Comp.1) was produced by bacteria proportionally to DIN supply. The protein-like FDOM component (Comp.2) was released irrespectively to phytoplankton or bacterial biomass, but depended on DIP and DIN concentrations. Under high DIN supply, Comp.2 was removed by bacterial reworking, leading to an accumulation of humic-like Comp.1. No influence of nutrient availability on amino acid-like FDOM component in peptide form (Comp.3) was observed. Comp.3 potentially acted as an intermediate product during formation or degradation of Comp.2. Our findings suggest that changes in nutrient concentrations may lead to substantial responses in the quantity and quality of optically active DOM and, therefore, might bias results of the applied in situ optical techniques for an estimation of DOC concentrations in open-ocean regions.

Complex sleep apnea syndrome

Directory of Open Access Journals (Sweden)

Wang J

2013-07-01

Full Text Available Juan Wang,1,* Yan Wang,1,* Jing Feng,1,2 Bao-yuan Chen,1 Jie Cao1 1Respiratory Department of Tianjin Medical University General Hospital, Tianjin, People's Republic of China; 2Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC, USA *The first two authors contributed equally to this work Abstract: Complex sleep apnea syndrome (CompSAS is a distinct form of sleep-disordered breathing characterized as central sleep apnea (CSA, and presents in obstructive sleep apnea (OSA patients during initial treatment with a continuous positive airway pressure (CPAP device. The mechanisms of why CompSAS occurs are not well understood, though we have a high loop gain theory that may help to explain it. It is still controversial regarding the prevalence and the clinical significance of CompSAS. Patients with CompSAS have clinical features similar to OSA, but they do exhibit breathing patterns like CSA. In most CompSAS cases, CSA events during initial CPAP titration are transient and they may disappear after continued CPAP use for 4–8 weeks or even longer. However, the poor initial experience of CompSAS patients with CPAP may not be avoided, and nonadherence with continued therapy may often result. Treatment options like adaptive servo-ventilation are available now that may rapidly resolve the disorder and relieve the symptoms of this disease with the potential of increasing early adherence to therapy. But these approaches are associated with more expensive and complicated devices. In this review, the definition, potential plausible mechanisms, clinical characteristics, and treatment approaches of CompSAS will be summarized. Keywords: complex sleep apnea syndrome, obstructive sleep apnea, central sleep apnea, apnea threshold, continuous positive airway pressure, adaptive servo-ventilation

Codon Bias Patterns of E. coli's Interacting Proteins.

Directory of Open Access Journals (Sweden)

Maddalena Dilucca

Full Text Available Synonymous codons, i.e., DNA nucleotide triplets coding for the same amino acid, are used differently across the variety of living organisms. The biological meaning of this phenomenon, known as codon usage bias, is still controversial. In order to shed light on this point, we propose a new codon bias index, CompAI, that is based on the competition between cognate and near-cognate tRNAs during translation, without being tuned to the usage bias of highly expressed genes. We perform a genome-wide evaluation of codon bias for E.coli, comparing CompAI with other widely used indices: tAI, CAI, and Nc. We show that CompAI and tAI capture similar information by being positively correlated with gene conservation, measured by the Evolutionary Retention Index (ERI, and essentiality, whereas, CAI and Nc appear to be less sensitive to evolutionary-functional parameters. Notably, the rate of variation of tAI and CompAI with ERI allows to obtain sets of genes that consistently belong to specific clusters of orthologous genes (COGs. We also investigate the correlation of codon bias at the genomic level with the network features of protein-protein interactions in E.coli. We find that the most densely connected communities of the network share a similar level of codon bias (as measured by CompAI and tAI. Conversely, a small difference in codon bias between two genes is, statistically, a prerequisite for the corresponding proteins to interact. Importantly, among all codon bias indices, CompAI turns out to have the most coherent distribution over the communities of the interactome, pointing to the significance of competition among cognate and near-cognate tRNAs for explaining codon usage adaptation. Notably, CompAI may potentially correlate with translation speed measurements, by accounting for the specific delay induced by wobble-pairing between codons and anticodons.

Maternal ADHD, Parenting, and Psychopathology Among Mothers of Adolescents With ADHD.

Science.gov (United States)

Babinski, Dara E; Pelham, William E; Molina, Brooke S G; Gnagy, Elizabeth M; Waschbusch, Daniel A; Wymbs, Brian T; Sibley, Margaret H; Derefinko, Karen J; Kuriyan, Aparajita B

2016-05-01

This study describes the parenting and psychopathology of mothers with ADHD of adolescents with ADHD (MCA), non-ADHD mothers of adolescents with ADHD (CA), and non-ADHD mothers of adolescents without ADHD (COMP). Two sets of pairwise comparisons: (a) COMP versus CA and (b) CA versus MCA were conducted. We hypothesized that CA would experience greater distress in parenting and psychopathology compared with COMP and that MCA would experience even more impairment compared with CA. Few differences emerged in comparisons of CA and COMP, with the exception of CA reporting greater parent-adolescent conflict and internalizing problems. In contrast, differences consistently emerged in comparisons of MCA and CA showing more difficulty for MCA in parenting and psychopathology. These findings underscore the need for treatments that address parental ADHD when adolescent ADHD is the intended target. © The Author(s) 2012.

Selection Behavior in the Market for Private Complementary Long-term Care Insurance in Germany

DEFF Research Database (Denmark)

Bauer, Jan; Schiller, Jörg; Schreckenberger, Christopher

is dominating in this market, with respect to both the decision to buy a CompLTCI policy and the decision about the extent of CompLTCI coverage. We identify occupational status, residential location and the holding of further supplementary health insurance policies as unused observables contributing...... to selection effects in this market. Our results suggest that non-linearitiesin the relationship of potential sources of selection to insurance coverage and risk should be considered. A panel data analysis shows that an increase in health insurance payouts is positively correlated with the uptake of Comp......In this paper, we analyze selection effects in the German market for private complementary longterm care insurance contracts (CompLTCI) within a static and dynamic framework. Using data on more than 98,000 individuals from a German insurance company, we provide evidence that advantageous selection...

UV-NIL replication of microlens arrays on flexible fluoropolymer substrates

DEFF Research Database (Denmark)

Jucius, Dalius; Lazauskas, Algirdas; Grigaliūnas, Viktoras

2018-01-01

This paper describes application of UV-NIL technique for the fabrication of hexagonal OrmoComp microlens arrays on flexible fluoropolymer substrates having exceptional chemical resistance, stability at elevated temperatures and high transmittance in the UV, visible, and infrared regions...... of the spectrum. Uniform and well-defined patterns of close-packed convex microlenses were formed in OrmoComp layers on H2 plasma treated FEP and ETFE substrates by UV-NIL replication of the metalized and liquid paraffin antiadhesive coated negative OrmoComp replicas of the master mold. UV-NIL replication...

High arterial compliance in cirrhosis is related to low adrenaline and elevated circulating calcitonin gene related peptide but not to activated vasoconstrictor systems

DEFF Research Database (Denmark)

Henriksen, Jens Henrik Sahl; Møller, S; Schifter, S

2001-01-01

catecholamines, renin activity, endothelin-1, and calcitonin gene related peptide (CGRP) at baseline and during oxygen inhalation. RESULTS: COMP(art) was significantly increased in cirrhotic patients compared with controls (1.32 v 1.06 ml/mm Hg; padrenaline levels (r=-0.......001) and central circulation time (r=-0.49; padrenaline (-16%; p... to COMP(art) disappeared. The relation of COMP(art) to CGRP and circulatory variables remained unchanged. CONCLUSION: Elevated arterial compliance in cirrhosis is related to low adrenaline, high CGRP, and systemic hyperdynamics but not to indicators of the activated vasoconstrictor systems (noradrenaline...

Cartilage oligomeric matrix protein in patients with juvenile idiopathic arthritis

DEFF Research Database (Denmark)

Bjørnhart, Birgitte; Juul, Anders; Nielsen, Susan

2009-01-01

Cartilage oligomeric matrix protein (COMP) has been identified as a prognostic marker of progressive joint destruction in rheumatoid arthritis. In this population based study we evaluated associations between plasma concentrations of COMP, disease activity, and growth velocity in patients...

C Chang foliar co es in g applic owpea growth cation cultiva h and n ...

African Journals Online (AJOL)

sunny

solutions is an important factor in controlling the severity of specific ion toxicities, ..... grown under hydroponic culture. J. Plant Physiol. 161:921-928. ... Zealand spinach (Tetragonia tretragonioides) and water spinach. (Ipomoea aquatica).

Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis

DEFF Research Database (Denmark)

Happonen, Kaisa E; Saxne, Tore; Aspberg, Anders

2010-01-01

Cartilage oligomeric matrix protein (COMP) is a structural component of cartilage, where it catalyzes collagen fibrillogenesis. Elevated amounts of COMP are found in serum during increased turnover of cartilage associated with active joint disease, such as rheumatoid arthritis (RA) and osteoarthr...

Integral or integrated marketing

Directory of Open Access Journals (Sweden)

Davčik Nebojša

2006-01-01

Full Text Available Marketing theorists and experts try to develop business efficient organization and to get marketing performance at higher, business integrated level since its earliest beginnings. The core issue in this paperwork is the dialectic and practical approach dilemma should we develop integrated or integral marketing approach in the organization. The presented company cases as well as dialectic and functional explanations of this dilemma clearly shows that integrated marketing is narrower approach than integral marketing if we take as focal point new, unique and completed entity. In the integration the essence is in getting different parts together, which do not have to make necessary the new entity. The key elements in the definition of the integral marketing are necessity and holistic, e.g. necessity to develop new, holistic entity.

An analytic solution to the homogeneous EIT problem on the 2D disk and its application to estimation of electrode contact impedances

International Nuclear Information System (INIS)

Demidenko, Eugene

2011-01-01

An analytic solution of the potential distribution on a 2D homogeneous disk for electrical impedance tomography under the complete electrode model is expressed via an infinite system of linear equations. For the shunt electrode model with two electrodes, our solution coincides with the previously derived solution expressed via elliptic integral (Pidcock et al 1995 Physiol. Meas. 16 77–90). The Dirichlet-to-Neumann map is derived for statistical estimation via nonlinear least squares. The solution is validated in phantom experiments and applied for breast contact impedance estimation in vivo. Statistical hypothesis testing is used to test whether the contact impedances are the same across electrodes or all equal zero. Our solution can be especially useful for a rapid real-time test for bad surface contact in clinical setting

Modeling serotonin uptake in the lung shows endothelial transporters dominate over cleft permeation

Science.gov (United States)

Bassingthwaighte, James B.

2013-01-01

A four-region (capillary plasma, endothelium, interstitial fluid, cell) multipath model was configured to describe the kinetics of blood-tissue exchange for small solutes in the lung, accounting for regional flow heterogeneity, permeation of cell membranes and through interendothelial clefts, and intracellular reactions. Serotonin uptake data from the Multiple indicator dilution “bolus sweep” experiments of Rickaby and coworkers (Rickaby DA, Linehan JH, Bronikowski TA, Dawson CA. J Appl Physiol 51: 405–414, 1981; Rickaby DA, Dawson CA, and Linehan JH. J Appl Physiol 56: 1170–1177, 1984) and Malcorps et al. (Malcorps CM, Dawson CA, Linehan JH, Bronikowski TA, Rickaby DA, Herman AG, Will JA. J Appl Physiol 57: 720–730, 1984) were analyzed to distinguish facilitated transport into the endothelial cells (EC) and the inhibition of tracer transport by nontracer serotonin in the bolus of injectate from the free uninhibited permeation through the clefts into the interstitial fluid space. The permeability-surface area products (PS) for serotonin via the inter-EC clefts were ∼0.3 ml·g−1·min−1, low compared with the transporter-mediated maximum PS of 13 ml·g−1·min−1 (with Km = ∼0.3 μM and Vmax = ∼4 nmol·g−1·min−1). The estimates of serotonin PS values for EC transporters from their multiple data sets were similar and were influenced only modestly by accounting for the cleft permeability in parallel. The cleft PS estimates in these Ringer-perfused lungs are less than half of those for anesthetized dogs (Yipintsoi T. Circ Res 39: 523–531, 1976) with normal hematocrits, but are compatible with passive noncarrier-mediated transport observed later in the same laboratory (Dawson CA, Linehan JH, Rickaby DA, Bronikowski TA. Ann Biomed Eng 15: 217–227, 1987; Peeters FAM, Bronikowski TA, Dawson CA, Linehan JH, Bult H, Herman AG. J Appl Physiol 66: 2328–2337, 1989) The identification and quantitation of the cleft pathway conductance from these

In vitro flowering in embryogenic cultures of Kinnow mandarin ...

African Journals Online (AJOL)

AJB SERVER

2006-08-17

Aug 17, 2006 ... Embryogenic cultures of Kinnow mandarin (C. nobilis Lour × C. deliciosa Tenora) were raised from unfertilized ovules ... development of efficient plant tissue culture procedures for in vitro ..... epiphytic orchid. Plant Physiol.

Sulfuric acid and hot water treatments enhance ex vitro and in vitro ...

African Journals Online (AJOL)

PRECIOUS

2009-11-16

Nov 16, 2009 ... vitro culture is conducted in a highly controlled environ- ment, it constitutes a ..... Constraints to symbiotic germination of terrestrial orchid seed in a. Mediterranean ... bioassays with tobacco tissue culture. Physiol. Plant.

AN INTEGRATED, ANIMATED MODEL OF THE (NA, K-ATPase HYDROLYTIC CYCLE

Directory of Open Access Journals (Sweden)

F.A. Leone

2006-07-01

Full Text Available The  (Na,  K-ATPase,  or  sodium  pump,  is  the  principal,  active  transport  system  that  establishes  sodium  and potassium  gradients  across  the  plasma  membranes  of  all  animal  cells.  Such  gradients  are  critical  to  sustaining important cellular functions like osmotic equilibrium, cell volume and pH homeostasis, among many others (Ann Rev Physiol 65: 817, 2003; Physiol 19: 377, 2004. This transport protein is a heterodimer that consists of a 110-kDa  -subunit  and  a  55-kDa,  glycosylated  -subunit.  A  group  of  seven  small  proteins,  known  as  FXYD  proteins  from  the sequence  of  a  conserved  motif  has  been  identified  recently,  and  one  of  these,  FXYD2,  constitutes  the  (Na,  K-ATPase  -subunit.  Our  model  is  based  on  conformational  changes  occurring  between  the  E1  and  E2  forms  of  the enzyme, which initiates its hydrolytic cycle at a high ATP/ADP ratio. While all steps are reversible, the model does not include  the reverse  reactions that can  take  place under appropriate conditions. The  E1 state  corresponds to that of the SERCA, recently crystallized (Science 304; 1672, 2004; Nature 430: 529, 2004. The animation was developed in Macromedia  Flash  8.0® and  illustrates  the  principle  of  an  alternating-access  model  of  an  ion  pump.  The  protein  is embedded  in  the  membrane  with  the  extracellular  face  uppermost  and  the  cytoplasmic  face  at  the  bottom.  Access from  the  cytoplasmic  or  extracellular  faces  to  the  cation-binding  sites,  located  in  the  transmembrane  moiety,  are controlled  by  two  gates  (moving  horizontal  bars,  and  conformations  showing  the  two  gates  closed  correspond  to states with occluded Na+ and K+ sites. Changes in cation-binding site structure entail

Studies on the relationship between cyanide-resistant respi-ration and expression of alternative oxidase in mung bean using antibodies prepared by synthetic polypeptide

Institute of Scientific and Technical Information of China (English)

LI; Chijun; (

2001-01-01

［1］Liang, Z., Liang, H. G., The respiratory metabolism of plants, in Plant Physiology and Molecular Biology (eds. Yu, S. W., Tang, Z. C.) (in Chinese), 2nd ed., Beijing: Science Press, 1998, 344-365.［2］Lü, C. S., Liang, H. G., Induced respiration in melon fruits, Scientia Sinica, 1963, 12(4): 616.［3］Liang, H. G., Lü, C. S., A comparative study of CN-resistant respiration in different cultures of tobacco callus, Plant Physiol., 1984, 75: 876.［4］Elthon, T. E., McIntosh, L., Identification of the alternative terminal oxidase of higher plant mitochondria, Proc. Natl. Acad. Sci. USA, 1987, 84: 8399.［5］Elthon, T. E., Nickels, R. L., McIntosh, L., Monoclonal antibodies to the alternative oxidase of higher plant mitochondria, Plant Physiol., 1989, 89: 1311.［6］Liang, W. S., Liang, H. G., Progress of the alternative oxidase, Chinese Bulletin of Botany (in Chinese), 1997, 14(2): 9.［7］Liang, W. S., Liang, H. G., Induction of alternative oxidase expression by endogenous ethylene in aging potato slices, Acta Phytophysiol. Sin. (in Chinese), 1999, 25(2): 205.［8］He, J. X., Wei, Z. Q., Liang, H. G., Effects of water stress on development, and operation and gene expression of cyanide-resistant respiratory pathway in wheat, Science in China, Ser. C, 1999, 42(3): 300.［9］McIntosh, L., Molecular biology of the alternative oxidase, Plant Physiol., 1994, 105: 781.［10］ Wang, J., Zhang, L. X., Liu, Z. L. et al., A possible calcium binding site in D1 protein: A fluorescence and FTIR study of the interaction between lanthanides and a synthetic peptide, Photosynthesis Research, 1995, 44: 297.［11］ Li, X. P., Du, L. F., Liang, H. G. et al., Preparation and identification of antidodecapeptide of polypeptide D1 or photosys-tem II reaction center, Prog. Biochem. Biophys. (in Chinese), 1997, 24(3): 283.［12］ Wen, J. Q., Liang, H. G., Studies on energy status and mitochondria respiration during growth and senescence of mung bean cotyledons, Physiol

Measuring Impact of EPAs Computational Toxicology Research (BOSC)

Science.gov (United States)

Computational Toxicology (CompTox) research at the EPA was initiated in 2005. Since 2005, CompTox research efforts have made tremendous advances in developing new approaches to evaluate thousands of chemicals for potential health effects. The purpose of this case study is to trac...

Genetics Home Reference: type 1 diabetes

Science.gov (United States)

... Jan 4. Review. Citation on PubMed or Free article on PubMed Central van Belle TL, Coppieters KT, von Herrath MG. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev. 2011 Jan;91( ...

Anti-diabetic and spermatogenic activity of Cocculus hirsutus (L) Diels

African Journals Online (AJOL)

Administrator

2007-05-16

May 16, 2007 ... lete or relative insufficiency of insulin secretion and insulin action (Balkau .... do not stimulate the pancreas and do not elevate circul- ating insulin levels. .... Physiology, section 7, Endocrinology, Am. Physiol. soc. Washington,.

Protective roles of nitric oxide on antioxidant systems in tall fescue ...

African Journals Online (AJOL)

ONOS

2010-01-18

Jan 18, 2010 ... Seedlings cultured hydroponically in a continuously aerated ... (Laspina et al., 2005; Sun et al., 2007) in 4 L of nutrient solution. (regenerated once ..... ascorbate-specific peroxidase in spinach chloroplasts. Plant Cell. Physiol.

Genetics and the Brain

Science.gov (United States)

... Epigenetic regulation of gene expression in physiological and pathological brain processes. Physiol Rev , 2011 Apr; 91(2): ... term potentiation and spine size enlargement. J. Neuroscience , March 18, 2009. 29(11):3395–3403 [xviii] Tapper, ...

Download this PDF file

African Journals Online (AJOL)

Shadan

2011-11-07

Nov 7, 2011 ... changes such as lipid peroxidation, protein, nucleic acids and photosynthetic ..... Responses of Antioxidants to Paraquat in Pea Leaves. Plant Physiol. .... enzymes and metabolism of 14 C-substrates in isolated leaf cells of.

Batch calculations in CalcHEP

International Nuclear Information System (INIS)

Pukhov, A.

2003-01-01

CalcHEP is a clone of the CompHEP project which is developed by the author outside of the CompHEP group. CompHEP/CalcHEP are packages for automatic calculations of elementary particle decay and collision properties in the lowest order of perturbation theory. The main idea prescribed into the packages is to make available passing on from the Lagrangian to the final distributions effectively with a high level of automation. According to this, the packages were created as a menu driven user friendly programs for calculations in the interactive mode. From the other side, long-time calculations should be done in the non-interactive regime. Thus, from the beginning CompHEP has a problem of batch calculations. In CompHEP 33.23 the batch session was realized by mean of interactive menu which allows to the user to formulate the task for batch. After that the not-interactive session was launched. This way is too restricted, not flexible, and leads to doubling in programming. In this article I discuss another approach how one can force an interactive program to work in non-interactive mode. This approach was realized in CalcHEP 2.1 disposed on http://theory.sinp.msu.ru/~pukhov/calchep.html

Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells.

Science.gov (United States)

Ferrini, Monica G; Garcia, Eduardo; Abraham, Andrea; Artaza, Jorge N; Nguyen, Sabine; Rajfer, Jacob

2018-06-01

COMP-4 is a natural compound-based dietary supplement consisting of the combination of ginger, Paullinia cupana, muira puama and l-citrulline, which when given long-term has been shown in the aged rat to a) upregulate iNOS in the penile smooth muscle cells (SMC), b) reverse the corporal SMC apoptosis and fibrosis associated with corporal veno-occlusive dysfunction (CVOD), and c) improve resulting erectile function. To elucidate the mechanism of how COMP-4 and its individual components modulate the iNOS-cGMP pathway, an in vitro study was conducted using a rat corporal primary SMC culture to determine its effect on NOS, soluble guanylate cyclase (sGC), cGMP and the phosphodiesterase 5 enzyme (PDE5). Primary SMC cultures using the explant technique were initiated by cutting small pieces of corporal tissue from 8 week old Sprague-Dawley rats. The SMC were grown in Dulbecco media with 20% fetal calf serum. The SMC were then incubated with or without COMP-4 (0.69 mg/ml) or its ingredients alone (ginger: 0.225 mg/ml; muira puama, Paullinia cupana and l-citrulline each at 0.9 mg/ml) for up to 24 h mRNA and protein were extracted and used for the determination of NOS, sGC and PDE5 content. cGMP content was determined by ELISA. L-NIL (4 μM) was used as an inhibitor of iNOS activity. Compared to the control values, COMP-4 upregulated expression of cGMP by 85%, induced a 42 fold increase in sGC as well as a 15 fold increase in both iNOS protein and mRNA content while it decreased both PDE5 mRNA and protein content each by about 50%. L-NIL completely inhibited the effect of COMP-4 on cGMP production. When compared with each of the individual four components of COMP-4, it appears that COMP-4 itself had the most profound effect in modulating each one the specific steps within the iNOS-cGMP pathway. This in vitro study demonstrates that COMP-4 is capable of activating the endogenous cellular iNOS-cGMP pathway within the CSM cells, which is theorized to be responsible

Security+ study guide study guide and practice exam

CERN Document Server

Dubrawsky, Ido; Dubrawsky

2007-01-01

Over 700,000 IT Professionals Have Prepared for Exams with Syngress Authored Study GuidesThe Security+ Study Guide & Practice Exam is a one-of-a-kind integration of text and and Web-based exam simulation and remediation. This system gives you 100% coverage of official CompTIA Security+ exam objectives plus test preparation software for the edge you need to achieve certification on your first try! This system is comprehensive, affordable, and effective!* Completely Guaranteed Coverage of All Exam ObjectivesAll five Security+ domains are covered in full: General Securi

Multidimensional singular integrals and integral equations

CERN Document Server

Mikhlin, Solomon Grigorievich; Stark, M; Ulam, S

1965-01-01

Multidimensional Singular Integrals and Integral Equations presents the results of the theory of multidimensional singular integrals and of equations containing such integrals. Emphasis is on singular integrals taken over Euclidean space or in the closed manifold of Liapounov and equations containing such integrals. This volume is comprised of eight chapters and begins with an overview of some theorems on linear equations in Banach spaces, followed by a discussion on the simplest properties of multidimensional singular integrals. Subsequent chapters deal with compounding of singular integrals

Structure identification by Mass Spectrometry Non-Targeted Analysis using the US EPA’s CompTox Chemistry Dashboard

Science.gov (United States)

Identification of unknowns in mass spectrometry based non-targeted analyses (NTA) requires the integration of complementary pieces of data to arrive at a confident, consensus structure. Researchers use chemical reference databases, spectral matching, fragment prediction tools, r...

Assessment of compost for suppression of Fusarium oxysporum and ...

African Journals Online (AJOL)

user

2012-08-28

Aug 28, 2012 ... Biological characteristics including compost inhabiting microbial ... A solid-liquid extraction was carried out then; pH was determined by using AS-501 pH ...... oxysporum in sweet basil. Crop Prot. ... Pesticide Biochem. Physiol.

Short Corr1munication

African Journals Online (AJOL)

1999). In vitro culture techniques have been used to study different aspects of gennination .... differentiation of protocomes, in seed callus of an orchid and correlated changes in free amino acids ... with tobacco tissue culture. Physiol. Plant.

Modeling and Event-Driven Simulation of Coordinated Multi-Point in LTE-Advanced with Constrained Backhaul

DEFF Research Database (Denmark)

Artuso, Matteo; Christiansen, Henrik Lehrmann

2014-01-01

multi-point joint transmission (CoMP JT). Field tests are generally considered impractical and costly for CoMP JT, therefore the need to provide a comprehensive and high-fidelity computer model to understand the impact of different design attributes and the applicability use cases. This paper presents...

Intracavernous Delivery of a Designed Angiopoietin-1 Variant Rescues Erectile Function by Enhancing Endothelial Regeneration in the Streptozotocin-Induced Diabetic Mouse

Science.gov (United States)

Jin, Hai-Rong; Kim, Woo Jean; Song, Jae Sook; Piao, Shuguang; Choi, Min Ji; Tumurbaatar, Munkhbayar; Shin, Sun Hwa; Yin, Guo Nan; Koh, Gou Young; Ryu, Ji-Kan; Suh, Jun-Kyu

2011-01-01

OBJECTIVE Patients with diabetic erectile dysfunction often have severe endothelial dysfunction and respond poorly to oral phosphodiesterase-5 inhibitors. We examined the effectiveness of the potent angiopoietin-1 (Ang1) variant, cartilage oligomeric matrix protein (COMP)-Ang1, in promoting cavernous endothelial regeneration and restoring erectile function in diabetic animals. RESEARCH DESIGN AND METHODS Four groups of mice were used: controls; streptozotocin (STZ)-induced diabetic mice; STZ-induced diabetic mice treated with repeated intracavernous injections of PBS; and STZ-induced diabetic mice treated with COMP-Ang1 protein (days −3 and 0). Two and 4 weeks after treatment, we measured erectile function by electrical stimulation of the cavernous nerve. The penis was harvested for histologic examinations, Western blot analysis, and cGMP quantification. We also performed a vascular permeability test. RESULTS Local delivery of the COMP-Ang1 protein significantly increased cavernous endothelial proliferation, endothelial nitric oxide (NO) synthase (NOS) phosphorylation, and cGMP expression compared with that in the untreated or PBS-treated STZ-induced diabetic group. The changes in the group that received COMP-Ang1 restored erectile function up to 4 weeks after treatment. Endothelial protective effects, such as marked decreases in the expression of p47phox and inducible NOS, in the generation of superoxide anion and nitrotyrosine, and in the number of apoptotic cells in the corpus cavernosum tissue, were noted in COMP-Ang1–treated STZ-induced diabetic mice. An intracavernous injection of COMP-Ang1 completely restored endothelial cell-cell junction proteins and decreased cavernous endothelial permeability. COMP-Ang1–induced promotion of cavernous angiogenesis and erectile function was abolished by the NOS inhibitor, N-nitro-L-arginine methyl ester, but not by the NADPH oxidase inhibitor, apocynin. CONCLUSIONS These findings support the concept of cavernous

Relationship between nitrogen and other chemical components in ...

African Journals Online (AJOL)

metabolism in the rumen. The higher stem lignin ... between nitrate reduction, protein synthesis and malate accumulation. Physiol. Plant. ... nitrate in plant tissue by nitration of salicylic acid. Comm. Soil Sci. Plant Anal. 6, 71. DEINUM, B., VAN ...

Department of Surgery, University of the Witwatersrand – a brief history

African Journals Online (AJOL)

result the departure of professors of anatomy and physiol- ogy was not permitted. .... details of the dog on which this surgery had been performed) and Underwood ... (Sholem Kay), breast cancer surgery (Myron Lange), thyroid diseases (Theo ...

Leukotriene B4 induces EMT and vimentin expression in PANC-1 pancreatic cancer cells: Involvement of BLT2 via ERK2 activation.

Science.gov (United States)

Kim, You Ri; Park, Mi Kyung; Kang, Gyeong Jin; Kim, Hyun Ji; Kim, Eun Ji; Byun, Hyun Jung; Lee, Moo-Yeol; Lee, Chang Hoon

2016-12-01

Leukotriene B 4 (LTB 4 ) is a leukocyte chemoattractant and plays a major role controlling inflammatory responses including pancreatitis. LTB 4 is known to be correlated with cancer progression. LTB 4 induces keratin phosphorylation and reorganization by activating extracellular regulated kinase (ERK) in PANC-1 pancreatic cancer cell lines. However, the role of LTB 4 in epithelial mesenchymal transition (EMT) and vimentin expression in pancreatic cancer cells is unknown. We examined whether LTB 4 induces EMT and vimentin expression by Western blot, si-RNA, and RT-PCR. LTB 4 induced morphological change, decreased E-cadherin expression and increased N-cadherin and vimentin expression. LTB4 increased migration and invasion of PANC-1 cancer cells. LTB 4 dose-dependently upregulated expression of vimentin in PANC-1 cancer cells. LTB 4 -induced vimentin expression was suppressed by LY255283 (BLT2 antagonist). Comp A, a BLT2 agonist, further increased vimentin expression. Gene silencing of BLT2 suppressed LTB 4 -or Comp A-induced vimentin expression in PANC-1 cells. The MEK inhibitor, PD98059 suppressed Comp A-induced vimentin expression. Comp A or transfection of plasmid containing BLT2 cDNA (pC BLT2 ) activated ERK, and BLT2 gene silencing suppressed Comp A-induced ERK activation. ERK2 siRNA abrogated Comp A-induced vimentin expression and ERK2 overexpression enhanced vimentin expression. One of well-known cause of ras mutation, cigarette smoke extracts increased BLT2 expression in PANC-1 cancer cells. Taken together, these results suggest that BLT2 is involved in LTB 4 -induced vimentin expression through ERK2 in PANC-1 cells. Copyright © 2016 Elsevier Ltd. All rights reserved.

Comparative evaluation of the sperm characteristics and ...

African Journals Online (AJOL)

olayemitoyin

J. Physiol. Sci. 29(June 2014) 055 –061 www.njps.com.ng. Comparative evaluation of the ... Summary: Cuscuta australis (C. australis) seed and stem are commonly used as .... 0.05, Values with different superscripts are significantly different.

The potential protective effects of erythropoietin and estrogen on ...

African Journals Online (AJOL)

Noha I. Hussien

2015-12-30

Dec 30, 2015 ... Kit to measure NO production following reduction of nitrate to nitrite using ..... tion of endothelial NO may eventually lead to the destruction of tubular ..... quent renal ischemia and reperfusion injury in mice. Am J Physiol.

Possible role of differential growth in airway wall remodeling in asthma

KAUST Repository

Moulton, D. E.; Goriely, A.

2011-01-01

Possible role of differential growth in airway wall remodeling in asthma. J Appl Physiol 110: 1003-1012, 2011. First published January 20, 2011; doi:10.1152/japplphysiol.00991.2010.- Airway remodeling in patients with chronic asthma is characterized

Comparação da profundidade de polimerização e microdureza de resinas bulk fill fotopolimerizáveis e de dupla-polimerização

OpenAIRE

Santos, Rute Maria Veredas dos

2016-01-01

Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz Objetivo: Avaliar e comparar a profundidade de polimerização e microdureza de compósitos bulk fill fotopolimerizáveis e de dupla-polimerização em diferentes períodos de tempo. Materiais e métodos: Confecionaram-se 25 amostras (n=25) para os compósitos fotopolimerizáveis Filtek™ Z250 (3M), Filtek™ Bulk Fill (3M), SonicFill™ 2 (Kerr) e x-tra fil (VOCO); n=40 para o compósito de dupla-polimeri...

Microcrystalline cellulose and sisal fibre reinforced cementitious composites

OpenAIRE

Ferreira, Stephany Maria Vieira

2016-01-01

Dissertação de mestrado integrado em Engenharia Civil (área de especialização em Perfil de Construções) Nas últimas décadas tem existido um crescente interesse em métodos alternativos de reforçar compósitos cimentícios. A utilização de fibras naturais como elemento de reforço tem sido bastante explorada ao longo dos anos, sendo que origina compósitos cimentícios com uma resistência ao impacto e à fissuração superior quando comparados com compósitos cimentícios comuns. Por outro...

Discrete-event simulation of coordinated multi-point joint transmission in LTE-Advanced with constrained backhaul

DEFF Research Database (Denmark)

Artuso, Matteo; Christiansen, Henrik Lehrmann

2014-01-01

Inter-cell interference in LTE-Advanced can be mitigated using coordinated multi-point (CoMP) techniques with joint transmission of user data . However, this requires tight coordination of the eNodeBs, usin g the X2 interface. In this paper we use discrete-event simulation to evaluate the latency...... requirements for the X2 interface and investigate the consequences of a constrained ba ckhaul. Our simulation results show a gain of the system throug hput of up to 120% compared to the case without CoMP for low-latency backhaul. With X2 latencies above 5 ms CoMP is no longer a benefit to the network....

Social Bots und Fake News - Was EU- und UNESCO-Referenzrahmen zum Lernen im digitalen Zeitalter darüber (nicht sagen

Directory of Open Access Journals (Sweden)

Dietmar Janetzko

2017-07-01

Full Text Available In den letzten Jahren haben internationale Organisationen wie die EU und die UNESCO eine Reihe von Vorschlägen und Strategiepapieren zur Bildung und Ausbildung im Zusammenhang mit digitalen Medien entwickelt. Mit den dabei entstandenen Rahmenkonzepten der EU (Digital Competence, DigComp sowie der UNESCO (Media and Information Literacy, MIL werden im Kern zwei zusammenhängende Ziele verfolgt: (i digitale Bildung bzw. digitale Kompetenzen, Fähigkeiten und zugehörige Einstellungen umfassend zu kartographieren sowie (ii über die dabei konzipierten edukativ-politischen Rahmenkonzepte Projektförderungen, Bildungs- bzw. Ausbildungsinitiativen sowie Gesetzesvorlagen anzustossen. Tatsächlich sind DigComp und MIL bereits dabei, auf internationaler Ebene einen prägenden Einfluss zu nahezu allen Fragen der Bildung und Ausbildung im Bereich digitaler Medien auszuüben. Beide Initiativen haben innerhalb der genannten Organisationen Leuchtturmcharakter, werden bislang aber von der allgemeinen Öffentlichkeit und der medienpädagogischen Fachöffentlichkeit kaum wahrgenommen. Dessen ungeachtet verbindet sich mit DigComp und MIL jeweils ein impliziter Anspruch auf einen – im Bedarfsfall zu aktualisierenden – Gesamtentwurf zur Analyse und Gestaltung medienpädagogischer Bildung und Ausbildung. Dies gilt für Gesetzesvorlagen, Regulierungen, Forschungsaktivitäten. Sind diese Rahmenkonzepte anschlussfähig an medienpädagogische Debatten über disruptive Versuche, in via soziale Medien geführte öffentliche Debatten einzugreifen, die sich über social bots, fake news oder andere Formen der Einflussnahme manifestieren? Erschliessen sie dazu Reflexionsräume und Handlungsoptionen? Geleitet von diesen Fragen betrachtet der vorliegende Aufsatz, die Rahmenkonzepte der EU und UNESCO, DigComp and MIL. Dabei zeigt sich, dass beide Rahmenkonzepte von Schieflagen gekennzeichnet sind. DigComp und MIL überbetonen die instrumentelle, auf Verwertung am

Aspectos da representação de Marco Túlio Cícero nos compêndios de História Universal do Ensino Secundário na Primeira República Brasileira (1889-1930 * Aspects of the representation of Marcus Tullius Cicero in textbooks on Universal History of the Second

Directory of Open Access Journals (Sweden)

ANDRÉ LUIZ CRUZ TAVARES

2012-04-01

Full Text Available O artigo tem como objetivo o estudo das origens e das características da representação de Marco Túlio Cícero (106-43 a.C. nos compêndios de História Universal utilizados no Ensino Secundário durante a Primeira República do Brasil (1888-1930, bem como a utilização dessa representação na construção identitária nacional republicana brasileira no início do século XX. Palavras-chave: Cícero – República – Brasil. Abstract: This paper aims to study the origins and characteristics of the representation of Marcus Tullius Cicero (103-46 BC in textbooks on Universal History used in Secondary Education during the First Republic of Brazil (1889-1930, as well as use of this representation in the Brazilian republican national identity construction in early twentieth century. Keywords: Cicero – Republic – Brazil.

Integration of Chandrasekhar's integral equation

International Nuclear Information System (INIS)

Tanaka, Tasuku

2003-01-01

We solve Chandrasekhar's integration equation for radiative transfer in the plane-parallel atmosphere by iterative integration. The primary thrust in radiative transfer has been to solve the forward problem, i.e., to evaluate the radiance, given the optical thickness and the scattering phase function. In the area of satellite remote sensing, our problem is the inverse problem: to retrieve the surface reflectance and the optical thickness of the atmosphere from the radiance measured by satellites. In order to retrieve the optical thickness and the surface reflectance from the radiance at the top-of-the atmosphere (TOA), we should express the radiance at TOA 'explicitly' in the optical thickness and the surface reflectance. Chandrasekhar formalized radiative transfer in the plane-parallel atmosphere in a simultaneous integral equation, and he obtained the second approximation. Since then no higher approximation has been reported. In this paper, we obtain the third approximation of the scattering function. We integrate functions derived from the second approximation in the integral interval from 1 to ∞ of the inverse of the cos of zenith angles. We can obtain the indefinite integral rather easily in the form of a series expansion. However, the integrals at the upper limit, ∞, are not yet known to us. We can assess the converged values of those series expansions at ∞ through calculus. For integration, we choose coupling pairs to avoid unnecessary terms in the outcome of integral and discover that the simultaneous integral equation can be deduced to the mere integral equation. Through algebraic calculation, we obtain the third approximation as a polynomial of the third degree in the atmospheric optical thickness

24 CFR 5.105 - Other Federal requirements.

Science.gov (United States)

2010-04-01

... implementing regulations at 24 CFR part 1; the Age Discrimination Act of 1975 (42 U.S.C. 6101-6107) and..., 1977 Comp., p. 393 and 3 CFR, 1987 Comp., p. 245) (Women's Business Enterprise). (b) Disclosure..., suspended, or ineligible contractors and participants. (d) Drug-Free Workplace. The Drug-Free Workplace Act...

Developing a Competency-Based Pan-European Accreditation Framework for Health Promotion

Science.gov (United States)

Battel-Kirk, Barbara; Van der Zanden, Gerard; Schipperen, Marielle; Contu, Paolo; Gallardo, Carmen; Martinez, Ana; Garcia de Sola, Silvia; Sotgiu, Alessandra; Zaagsma, Miriam; Barry, Margaret M.

2012-01-01

Background: The CompHP Pan-European Accreditation Framework for Health Promotion was developed as part of the CompHP Project that aimed to develop competency-based standards and an accreditation system for health promotion practice, education, and training in Europe. Method: A phased, multiple-method approach was employed to facilitate consensus…

On a User-Centric Base Station Cooperation Scheme for Reliable Communications

DEFF Research Database (Denmark)

Kim, Dong Min; Thomsen, Henning; Popovski, Petar

2017-01-01

In this paper, we describe CoMP2flex, a user-centric base station (BS) cooperation scheme that provides improvements in reliability of both uplink (UL) and downlink (DL) communications of wireless cellular networks. CoMP2flex supports not only cooperation of two BSs with same direction of traffic...

75 FR 11988 - Aviation Proceedings, Agreements Filed the Week Ending February 27, 2010

Science.gov (United States)

2010-03-12

... Air Transport Association. Subject: Mail Vote 625--Resolution 010p, TC3 Japan, Korea-South East Asia...: Members of the International Air Transport Association. Subject: PTC COMP Mail Vote 620, Resolution 024d... International Air Transport Association. Subject: PTC COMP Mail Vote 626, Resolution 011a, Mileage Manual Non TC...

BIO GRA PIEË VAN SE WENT IE NDE EN AGT IE NDEEEUSE SU ID

African Journals Online (AJOL)

Test

den Raad aangewezen en vertoond eene bekwame gelegenheid, in 's. Comp. verlaten Tuin, om aldaar eene goede begrafenisplaats te ordin- neren. en daar ter plaatse door de Diaconie, of de Ed. Comp. vooreerst een ommuurd Kerkhof, en met ter tijd een behoorlijk proper kerkje te laten maken, waarin de gequalificeerde ...

Evaluation of Patterns and Spatial Trends of Pesticide Residues

African Journals Online (AJOL)

dell

PCA of the data sets for pesticide residues in water, soil and sediments samples from ..... J. Sci. 38(3), 2012. 189. 0.00. 0.20. 0.40. 0.60. 0.80. 1.00. Comp[1]. Comp[2]. R. 2. X. (c u m. ) & ..... Environmental Management, 60: 215-. 225. Wiberg K ...

Modulation of sensory inhibition of motor evoked potentials elicited by TMS prior to movement?

DEFF Research Database (Denmark)

Leukel, Christian; Lundbye-Jensen, Jesper; Nielsen, Jens Bo

because the afferent information triggered the movement and therefore was important for motor performance. Alle et al. (2009). J Physiol 587:5163-5176 Chen et al. (1998). Ann Neurol 44:317-325 Tokimura et al. (2000). J Physiol 523 Pt 2:503-513......Short latency afferent inhibition (SAI) refers to a decrement of the size of a motor evoked potential (MEP) by transcranial magnetic stimulation (TMS) after electrical stimulation of a peripheral afferent nerve (PNS) (Tokimura et al. 2000). Since SAI occurs when TMS is applied at the time...... of corticospinal cells to TMS, which starts approximately 100 ms prior to the onset of movement (Chen et al. 1998). Thus, it is hypothesized that the modulation of the MEP prior to movement is linked to the afferent volley arriving at the sensorimotor cortex. It might be speculated that the MEP was facilitated...

Collagen XII and XIV, New Partners of Cartilage Oligomeric Matrix Protein in the Skin Extracellular Matrix Suprastructure*

Science.gov (United States)

Agarwal, Pallavi; Zwolanek, Daniela; Keene, Douglas R.; Schulz, Jan-Niklas; Blumbach, Katrin; Heinegård, Dick; Zaucke, Frank; Paulsson, Mats; Krieg, Thomas; Koch, Manuel; Eckes, Beate

2012-01-01

The tensile and scaffolding properties of skin rely on the complex extracellular matrix (ECM) that surrounds cells, vasculature, nerves, and adnexus structures and supports the epidermis. In the skin, collagen I fibrils are the major structural component of the dermal ECM, decorated by proteoglycans and by fibril-associated collagens with interrupted triple helices such as collagens XII and XIV. Here we show that the cartilage oligomeric matrix protein (COMP), an abundant component of cartilage ECM, is expressed in healthy human skin. COMP expression is detected in the dermal compartment of skin and in cultured fibroblasts, whereas epidermis and HaCaT cells are negative. In addition to binding collagen I, COMP binds to collagens XII and XIV via their C-terminal collagenous domains. All three proteins codistribute in a characteristic narrow zone in the superficial papillary dermis of healthy human skin. Ultrastructural analysis by immunogold labeling confirmed colocalization and further revealed the presence of COMP along with collagens XII and XIV in anchoring plaques. On the basis of these observations, we postulate that COMP functions as an adapter protein in human skin, similar to its function in cartilage ECM, by organizing collagen I fibrils into a suprastructure, mainly in the vicinity of anchoring plaques that stabilize the cohesion between the upper dermis and the basement membrane zone. PMID:22573329

Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure.

Science.gov (United States)

Agarwal, Pallavi; Zwolanek, Daniela; Keene, Douglas R; Schulz, Jan-Niklas; Blumbach, Katrin; Heinegård, Dick; Zaucke, Frank; Paulsson, Mats; Krieg, Thomas; Koch, Manuel; Eckes, Beate

2012-06-29

The tensile and scaffolding properties of skin rely on the complex extracellular matrix (ECM) that surrounds cells, vasculature, nerves, and adnexus structures and supports the epidermis. In the skin, collagen I fibrils are the major structural component of the dermal ECM, decorated by proteoglycans and by fibril-associated collagens with interrupted triple helices such as collagens XII and XIV. Here we show that the cartilage oligomeric matrix protein (COMP), an abundant component of cartilage ECM, is expressed in healthy human skin. COMP expression is detected in the dermal compartment of skin and in cultured fibroblasts, whereas epidermis and HaCaT cells are negative. In addition to binding collagen I, COMP binds to collagens XII and XIV via their C-terminal collagenous domains. All three proteins codistribute in a characteristic narrow zone in the superficial papillary dermis of healthy human skin. Ultrastructural analysis by immunogold labeling confirmed colocalization and further revealed the presence of COMP along with collagens XII and XIV in anchoring plaques. On the basis of these observations, we postulate that COMP functions as an adapter protein in human skin, similar to its function in cartilage ECM, by organizing collagen I fibrils into a suprastructure, mainly in the vicinity of anchoring plaques that stabilize the cohesion between the upper dermis and the basement membrane zone.

Lipid Profile and High Maternal Body Mass Index is Associated with ...

African Journals Online (AJOL)

Background: Preeclampsia is a leading cause of maternal mortality worldwide ... as earlier studies conducted by Turpin et al., (2008) focused on ..... Physiol Res 2006;55:491‑500. 9. ... Teichmann AT, Wieland H, Cremer P, Kulow G, Mehle U.

Unraveling possible association between quantitative trait loci (QTL ...

African Journals Online (AJOL)

fire7-

2016-10-05

Oct 5, 2016 ... The genes for host basal resistance seem to play similar roles in basal .... purpose DNA of each QTL-NILs was isolated following the CTAB isolation method ..... never sleep: non-host resistance in plants. J. Plant Physiol.

Influence of soil drought stress on photosynthesis, carbohydrates ...

African Journals Online (AJOL)

USER

2010-08-16

Aug 16, 2010 ... and the ability of plant to adapt to drought stress. (Bulbotko, 1973; Atkinson et ... drought stress. In general, little is known about the effects of soil drought ..... fluorescence, water relations, and leaf abscisic acid. Plant Physiol.

Effects of salmon calcitonin and calcitonin gene related peptide ...

African Journals Online (AJOL)

STORAGESEVER

2009-04-20

Apr 20, 2009 ... mucus and phospholipids in rats exposed to cold + restraint stress (CRS). .... and CGRP (10 µg/kg) were dissolved in sterile distilled water and injected ..... Liver. Physiol. 280: G470-G474. Allen A, Flemstrom G (2005).

Effect of soil salinity on the growth, amino acids and ion contents of ...

African Journals Online (AJOL)

jamil

2012-10-25

Oct 25, 2012 ... The response of plants to salt stress occurs in two ways, 1st is the rapid response ... hormone mediated process and control of plant senescence (Walters ..... Polyamines in plant-microbe interactions. Physiol. Mol. Plant Pathol ...

Computer Program Development Specification for Ada Integrated Environment. Ada Compiler Phases B5-AIE (1). COMP (1).

Science.gov (United States)

1982-11-05

INTERMETRICS INCORPORATED * 733 CONCORD AVENUE e CAMBRIDGE, MASSACHUSETTS 02138 1 6171 861-1340 B5-AIE(l) .COt4P(1) SET U _j ISTING AST.’ ISTINGDIN...header EZMAP DS A-OAMAP ’ address of exception handler map -- Code (instructions and literals) follows BODY ZQU * entry point to the unit Ist ...exceed a figure to be determined. (3) VIH limits the compiler to 200 subdomains accessible at once. This limits the number of units that may be WITHd

Pharmacophore-based screening of differentially-expressed PGF, DDIT4, COMP and CHI3L1 from hMSC cell lines reveals five novel therapeutic compounds for primary osteoporosis

Directory of Open Access Journals (Sweden)

Catherine Jessica Lai

2016-06-01

Full Text Available As many societies age, primary osteoporosis (PO is increasingly a major health problem. Current drug treatments such as alendronate and risedronate have known side effects. We took an agnostic empirical approach to find PO therapeutic compounds. We examined 13,548,960 probe data-points from mesenchymal stromal cell (hMSC lines and found that PGF, DDIT4, and COMP to be up-regulated, and CHI3L1, down-regulated. We then identified their druggable domains. For the up-regulated differentially-expressed genes, we used protein–protein interactions to find residue clusters as binding surfaces. We then employed pharmacophore models to screen 15,407,096 conformations of 22,723,923 compounds, which identified (6R,9R-6-(2-furyl-9-(1H-indol-3-yl-2-(trifluoromethyl-5,6,7, 9-tetrahydro-4H[1,2,4]triazolo[5,1],(2S-N1-[2-[2-(methylamino-2-oxo-ethyl]phenyl]-N2-phenylpyrrolidine-1,2-dicarboxamide, and 2-furyl-(1H-indol-3-yl-methyl-BLAHone as candidate compounds. For the down-regulated CH13L1, we relied on genome-wide disease signatures to identify (11alpha-9-fluoro-11,17,21-trihydroxypregn-4-ene-3,20-dione and Genistein as candidate compounds. Our approach differs from previous research as we did not confine our drug targets to hypothesized compounds in the existing literature. Instead, we allowed the full expression profile of PO cell lines to reveal the most desirable targets. Second, our differential gene analysis revealed both up- and down-regulated genes, in contrast to the literature, which has focused on inhibiting only up-regulated genes. Third, our virtual screening universe of 22,723,923 compounds was more than 100 times larger than those in the known literature.

Response of loblolly pine to complete woody and herbaceous control: projected yields and economic outcomes - the COMProject

Science.gov (United States)

James H. Miller; R.L. Busby; B.R. Zutter; S.M. Zedaker; M.B. Edwards; R.A. Newbold

1995-01-01

Abstract.Age-8 and -9 data from the 13 study plantations of the Competition Omission Monitoring Project (COMP) were used to project yields and derive economic outcomes for loblolly pine (Pinus taeda L.). COMP treatments were chop-burn, complete woody plant control, complete herbaceous plant control for 4 years, and complete woody...

TMFunction data: 656 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available , Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis -78.7 Electrogenic ...Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

Water stress induces overexpression of superoxide dismutases that ...

African Journals Online (AJOL)

SERVER

2007-09-05

Sep 5, 2007 ... Water stress is known to induce active oxygen species in plants. ... photosystem II photochemistry and whole plant growth against oxidative stress in these plants. ..... CO2. Plant Physiol. 110: 393-402. Sen Gupta A, Heinen JL, ...

Reference: 73 [Arabidopsis Phenome Database[Archive

Lifescience Database Archive (English)

Full Text Available et al. 2004 Mar. Plant Physiol. 134(3):1039-49. The availability of nitrogen is a limiting factor for plant growth in most soil...s. Allantoin and its degradation derivatives are a group of soil heterocyclic nitrogen co

Breeding elite japonica-type soft rice with high protein content ...

African Journals Online (AJOL)

STORAGESEVER

2009-01-19

Jan 19, 2009 ... hygromycin-resistant calli and regeneration of transgenic plants were performed ... Thirty rice seeds at the top of the ears of transgenic plants and the .... greater effect on the GC than the GT apart from its ability .... Cell Physiol.

A DHHC-type zinc finger protein gene regulates shoot branching in ...

African Journals Online (AJOL)

hope&shola

Arabidopsis. Key words: Arabidopsis, DHHC-type zinc finger protein, At5g04270, shoot branching. ..... and human HIP14 (Ducker et al., 2004), were isolated and identified to .... the control of branching in the rms1 mutant of pea. Plant Physiol.

75 FR 18084 - Changes in Flood Elevation Determinations

Science.gov (United States)

2010-04-09

... Street SW., Washington, DC 20472, (202) 646-2820, or (e-mail) [email protected] . SUPPLEMENTARY....; Reorganization Plan No. 3 of 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p. 376..., 2009; Wasserman, Mayor, City The Argus. of Freemont, 3300 Capitol Avenue, Fremont, CA 94538. San Diego...

75 FR 35674 - Changes in Flood Elevation Determinations

Science.gov (United States)

2010-06-23

..., DC 20472, (202) 646-2820, or (e-mail) [email protected] . SUPPLEMENTARY INFORMATION: The Federal... 1978, 3 CFR, 1978 Comp., p. 329; E.O. 12127, 44 FR 19367, 3 CFR, 1979 Comp., p.376. Sec. 65.4 [Amended... Argus. of Freemont, 3300 Capitol Avenue, Fremont, CA 94538. Riverside (FEMA Docket No.: B- City of...

LES COMPETENCES LANGAGIERES – SUGGESTION POUR UNE ADAPTATION STRATEGIQUE DANS LE MANAGEMENT DE L'ENTREPRISE

Directory of Open Access Journals (Sweden)

Constantin Felicia

2010-07-01

Full Text Available La dynamique de la société actuelle privilégie la libre circulation des personnes et de l'information. L'Europe, sans les frontières physiques qui séparaient autrefois les peuples, fournit le sentiment naturel d'un espace global, aujourd'hui violemment frappé par la crise économique. Dans le contexte des réductions des budgets, les entreprises doivent se redresser par l'implémentation de stratégies compétitives. Le modèle de la roue compétitive de Marc Ingham permet d'envisager les ressources humaines et leurs compétences linguistiques comme une valeur ajoutée, facteur stratégique révélateur de différences. La formation langagière étant cependant dispendieuse, nous suggérons une solution équilibrée et économique: la formation aux compétences partielles en langues étrangères par l'intercompréhension linguistique.

Multiple epiphyseal dysplasia: radiographic abnormalities correlated with genotype

Energy Technology Data Exchange (ETDEWEB)

Unger, S.L. [Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Los Angeles, CA (United States); Briggs, M.D.; Holden, P. [Wellcome Trust Centre for Cell-Matrix Research, University of Manchester (United Kingdom); Zabel, B. [Children' s Hospital, Univ. of Mainz (Germany); Ala-Kokko, L.; Paassilta, P.; Lohiniva, J. [Dept. of Medical Biochemistry, Univ. of Oulu (Finland); Rimoin, D.L. [Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Los Angeles, CA (United States); Department of Pediatrics, UCLA School of Medicine, Los Angeles, CA (United States); Lachman, R.S. [Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Los Angeles, CA (United States); Department of Pediatrics, UCLA School of Medicine, Los Angeles, CA (United States); Department of Radiology, UCLA School of Medicine, Los Angeles, CA (United States); Cohn, D.H. [Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Los Angeles, CA (United States); Department of Human Genetics, UCLA School of Medicine, Los Angeles, CA (United States)

2001-01-01

Multiple epiphyseal dysplasia (MED) is an osteochondrodysplasia characterized clinically by mild short stature and early-onset degenerative joint disease and radiographically by epiphyseal hypoplasia/dysplasia. MED is genetically heterogeneous, with autosomal dominant cases resulting from mutations in at least three genes: the cartilage oligomeric matrix protein (COMP) gene (EDM1) and the COL9A2 (EDM2) and COL9A3 (EDM3) genes of type IX procollagen. We present here a comparison of the radiographic phenotypes of MED patients with type IX collagen gene mutations and those with COMP gene mutations. We reviewed radiographs from two patients with MED produced by COMP mutations, two families with COL9A2 mutations, and one family with a mutation in COL9A3. The data demonstrated that the patients with type IX collagen defects had more severe joint involvement at the knees and relative hip sparing, while the patients with COMP mutations had significant involvement at the capital femoral epiphyses and irregular acetabuli. This pattern of joint involvement was consistent regardless of overall degree of severity of the phenotype. (orig.)

A rank-based algorithm of differential expression analysis for small cell line data with statistical control.

Science.gov (United States)

Li, Xiangyu; Cai, Hao; Wang, Xianlong; Ao, Lu; Guo, You; He, Jun; Gu, Yunyan; Qi, Lishuang; Guan, Qingzhou; Lin, Xu; Guo, Zheng

2017-10-13

To detect differentially expressed genes (DEGs) in small-scale cell line experiments, usually with only two or three technical replicates for each state, the commonly used statistical methods such as significance analysis of microarrays (SAM), limma and RankProd (RP) lack statistical power, while the fold change method lacks any statistical control. In this study, we demonstrated that the within-sample relative expression orderings (REOs) of gene pairs were highly stable among technical replicates of a cell line but often widely disrupted after certain treatments such like gene knockdown, gene transfection and drug treatment. Based on this finding, we customized the RankComp algorithm, previously designed for individualized differential expression analysis through REO comparison, to identify DEGs with certain statistical control for small-scale cell line data. In both simulated and real data, the new algorithm, named CellComp, exhibited high precision with much higher sensitivity than the original RankComp, SAM, limma and RP methods. Therefore, CellComp provides an efficient tool for analyzing small-scale cell line data. © The Author 2017. Published by Oxford University Press.

Aligning the National S&T Policy with the National Sustainable ...

International Development Research Centre (IDRC) Digital Library (Canada)

Compétences, gouvernance et nanotechnologies : pleins feux sur l'Inde. La nanotechnologie est la fabrication ou l'utilisation de matières ayant des dimensions comprises entre 1 et 100 nanomètres (1 mètre = 1 milliard de nanomètres) environ. Voir davantageCompétences, gouvernance et nanotechnologies : pleins feux ...

Hybrid palliation for critical systemic outflow obstruction: neither rapid stage 1 Norwood nor comprehensive stage 2 mitigate consequences of early risk factors.

Science.gov (United States)

Davies, Ryan R; Radtke, Wolfgang; Bhat, Majeed A; Baffa, Jeanne M; Woodford, Edward; Pizarro, Christian

2015-01-01

Hybrid palliation with branch pulmonary artery banding (bPAB) has become increasingly common in the early management of patients with critical left ventricular outflow obstruction. Optimal subsequent surgical palliation remains undefined. We retrospectively reviewed patients undergoing initial bPAB for single ventricle physiology with systemic outflow obstruction (2001-2013, n = 37). Patients were stratified by subsequent surgical palliation: stage 1 Norwood (St1N, n = 14), comprehensive stage 2 (CompSt2, n = 11), and none (n = 12). bPAB was performed at a median of 4 days and 2.7-kg, post-bPAB mortality was increased in patients with aortic atresia (odds ratio [OR] = 3.8, 95% confidence interval [CI] = 0.9-15.8) or birth weight <2 kg (OR = 13.8, 95% CI = 1.4-136.4). Palliation strategy did not affect transplant-free survival through second-stage palliation (St1N: 71.4%, CompSt2: 72.7%, P = .9). Among CompSt2 patients, there was a trend toward poorer survival with aortic atresia (0% vs 80%, P = .09); birth weight <2.5 kg was associated with decreased survival (0% vs 89.0%, P = .01). A trend toward lower survival with low birth weight was evident among St1N patients (<2 kg, OR = 0.1, 95% CI = 0.01-1.9, P = .09). CompSt2 mortality occurred on postoperative days 0 and 1. Mortality following St1N occurred at a median of 38.5 days (range = 23.5-104.5). Among survivors of stage 2 palliation, Fontan completion was performed in the same number of patients in each group (St1N: 6/8, 75%, CompSt2: 6/8, 75%). Both St1N and CompSt2 are viable options for subsequent palliation following initial hybrid procedure. Transplant-free survival and eventual Fontan candidacy are similar between groups. Delaying surgical palliation with the CompSt2 did not mitigate the impact of early risk factors such as low birth weight and aortic atresia. Copyright © 2015 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

Effect of irradiation mode and filling technique on resin/dentin bonding strength in class I cavities Efeito do modo de ativação e da técnica restauradora na resistência de união entre compósito e dentina em cavidades classe I

Directory of Open Access Journals (Sweden)

Alex José Souza dos Santos

2004-09-01

Full Text Available Factors such as light-curing mode, filling technique and cavity configuration may affect the bonding strength to dentin. This study evaluated the effect of irradiation mode and filling technique on resin/dentin bonding strength on the buccal wall of class I cavities in human teeth. Occlusal enamel was removed to expose a flat dentin surface. Occlusal cavities (4 x 3 x 3 mm were prepared in dentin. The adhesive Single Bond was applied according to the manufacturer's instructions and TPH Spectrum composite resin was placed using the following: oblique incremental, horizontal incremental or bulk filling techniques. The composite resin was light-cured either by continuous (600 mW/cm² for 40 s or Soft-Start (250 mW/cm² for 10 s + 600 mW/cm² for 30 s modes. Specimens of the control group were obtained by bonding the material to the flat exposed buccal wall of the cavity (C-factor = 1. The teeth were stored in water at 37ºC for 24 h and prepared for microtensile testing. Bonded beams of approximately 0.8 mm² were obtained from the buccal wall and tested with a tension of 0.5 mm/min. Results were analyzed by two-way ANOVA, Tukey's test and Dunnett's test (alpha = 0.05. Incremental placement techniques with both irradiation modes produced higher bonding strength values than the bulk technique (p Fatores como o modo de ativação, a técnica restauradora e a configuração cavitária podem afetar a resistência adesiva à dentina. Este estudo avaliou os efeitos dos modos de ativação e das técnicas restauradoras na resistência de união compósito/dentina na parede vestibular de restaurações classe I. O esmalte oclusal dos dentes foi removido para expor uma superfície dentinária planificada. Cavidades oclusais (4 x 3 x 3 mm foram preparadas em dentina. O adesivo Single Bond foi aplicado de acordo com as instruções do fabricante, e o compósito TPH Spectrum, inserido através de três diferentes técnicas: oblíqua incremental, horizontal

Dynamic exercise enhances regional cerebral artery mean flow velocity

DEFF Research Database (Denmark)

Linkis, P; Jørgensen, L G; Olesen, H L

1995-01-01

Dynamic exercise enhances regional cerebral artery mean flow velocity. J. Appl. Physiol. 78(1): 12-16, 1995.--Anterior (ACA) and middle (MCA) cerebral artery mean flow velocities (Vmean) and pulsatility indexes were determined using transcranial Doppler in 14 subjects during dynamic exercise afte...

TMFunction data: 665 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... 0 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 660 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... 0 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 659 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... 0 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 666 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... 0 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 657 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... 0 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 668 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... 0 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 658 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... 0 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

Perinatal and chronic hypothyroidism impair behavioural development in male and female rats.

NARCIS (Netherlands)

Wijk, van N.; Rijntjes, E.; Heijning, van de B.J.

2008-01-01

Perinatal and chronic hypothyroidism impair behavioural development in male and female rats. EXP PHYSIOL 00(0) 000-000, 0000. - A lack of thyroid hormone, i.e. hypothyroidism, during early development results in multiple morphological and functional alterations in the developing brain. In the

Genetics Home Reference: Tangier disease

Science.gov (United States)

... Maxfield FR, Tabas I. Role of cholesterol and lipid organization in disease. Nature. 2005 Dec 1;438(7068):612-21. ... Hubácek JA. ATP-binding cassette (ABC) transporters in human metabolism and diseases. Physiol Res. 2004;53(3):235-43. Review. ...

Effect of road transport stress on Erthrocyte Osmotic Fragility (EOF ...

African Journals Online (AJOL)

olayemitoyin

body of the vehicle was made of steel and the floor of ... height and the body mass index were noted and recorded ... Instruments Co., China) placed sublingually for 2 -3 ..... exercise. Eur. J. Appl. Physiol. 67: 132-137. Von- Borell, E. H. (2001).

Heavy metals and nutritional composition of some selected herbal ...

African Journals Online (AJOL)

saad

2012-09-20

Sep 20, 2012 ... Co, Cr, Hg, Mn, Ni, Pb and Zn) are toxic and lead to ... A stock standard solution of chloride and nitrate salts of zinc (Zn), copper (Cu), Iron (Fe), ..... of mouse neuronal excitability in culture of mouse hippocampus. J. physiol.

Associateship | Indian Academy of Sciences

Indian Academy of Sciences (India)

Home; Fellowship; Associateship. Associate Profile. Period: 1987–1989. Marimuthu, Dr G. Date of birth: 25 February 1954. Specialization: Chronobiology Address during Associateship: Dept. of Animal Behaviour & Physiol, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021. YouTube; Twitter ...

International Symposium on the Biology and Management of Aquatic Plants. Volume 31

Science.gov (United States)

1993-01-01

Yang. 1991. Lipid peroxidation and antioxidative transgenic plants overexpressing peroxidase. Plant Physiol 96:577- defense systems in early leaf...Factors 3. Chandrasena, J. P. N. R. and W. H. T. Dhammika. 1988. Studies on limiting the distribution of cogongrass, Imperata cylindrica, and torpe

Predicted Thermal Responses of Military Working Dog (MWD) to Chemical, Biological, Radiological, Nuclear (CBRN) Protective Kennel Enclosure

Science.gov (United States)

2011-08-01

used ( Hemingway , 1961; Crawford, 1962; Schmidt-Nielsen, 1970; Meyer, 1989). The panting frequency depends on individual MWD anthropometrics...of temperature regulation in the unanesthetized dog. J. Appl. Physiol. 213(2):547-556. 12. Hemingway , A. 1961. The panting response of normal un

SANCnews: Sector 4f, charged current TH1"-->

Science.gov (United States)

Arbuzov, A.; Bardin, D.; Bondarenko, S.; Christova, P.; Kalinovskaya, L.; Nanava, G.; Sadykov, R.; von Schlippe, W.

2007-08-01

In this paper we describe the implementation of the charged current decays of the type t→bl+νl(γ) in the framework of the SANC system. All calculations are done taking into account the one-loop electroweak correction in the standard model. The emphasis of this paper is on the presentation of numerical results. Various distributions are produced by means of a Monte Carlo integrator and event generator. Comparison with the results of the CompHEP and PYTHIA packages are presented for the Born and hard photon contributions. The validity of the cascade approximation at one-loop level is also studied.

Long Pulse Integrator of Variable Integral Time Constant

International Nuclear Information System (INIS)

Wang Yong; Ji Zhenshan; Du Xiaoying; Wu Yichun; Li Shi; Luo Jiarong

2010-01-01

A kind of new long pulse integrator was designed based on the method of variable integral time constant and deducting integral drift by drift slope. The integral time constant can be changed by choosing different integral resistors, in order to improve the signal-to-noise ratio, and avoid output saturation; the slope of integral drift of a certain period of time can be calculated by digital signal processing, which can be used to deduct the drift of original integral signal in real time to reduce the integral drift. The tests show that this kind of long pulse integrator is good at reducing integral drift, which also can eliminate the effects of changing integral time constant. According to experiments, the integral time constant can be changed by remote control and manual adjustment of integral drift is avoided, which can improve the experiment efficiency greatly and can be used for electromagnetic measurement in Tokamak experiment. (authors)

Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty.

Science.gov (United States)

Stout, Michael B; Justice, Jamie N; Nicklas, Barbara J; Kirkland, James L

2017-01-01

Advancing age is associated with progressive declines in physiological function that lead to overt chronic disease, frailty, and eventual mortality. Importantly, age-related physiological changes occur in cellularity, insulin-responsiveness, secretory profiles, and inflammatory status of adipose tissue, leading to adipose tissue dysfunction. Although the mechanisms underlying adipose tissue dysfunction are multifactorial, the consequences result in secretion of proinflammatory cytokines and chemokines, immune cell infiltration, an accumulation of senescent cells, and an increase in senescence-associated secretory phenotype (SASP). These processes synergistically promote chronic sterile inflammation, insulin resistance, and lipid redistribution away from subcutaneous adipose tissue. Without intervention, these effects contribute to age-related systemic metabolic dysfunction, physical limitations, and frailty. Thus adipose tissue dysfunction may be a fundamental contributor to the elevated risk of chronic disease, disability, and adverse health outcomes with advancing age. ©2017 Int. Union Physiol. Sci./Am. Physiol. Soc.

A mathematical model of endovascular heat transfer for human brain cooling

Science.gov (United States)

Salsac, Anne-Virginie; Lasheras, Juan Carlos; Yon, Steven; Magers, Mike; Dobak, John

2000-11-01

Selective cooling of the brain has been shown to exhibit protective effects in cerebral ischemia, trauma, and spinal injury/ischemia. A multi-compartment, unsteady thermal model of the response of the human brain to endovascular cooling is discussed and its results compared to recent experimental data conducted with sheep and other mammals. The model formulation is based on the extension of the bioheat equation, originally proposed by Pennes(1) and later modified by Wissler(2), Stolwijk(3) and Werner and Webb(4). The temporal response of the brain temperature and that of the various body compartments to the cooling of the blood flowing through the common carotid artery is calculated under various scenarios. The effect of the boundary conditions as well as the closure assumptions used in the model, i.e. perfusion rate, metabolism heat production, etc. on the cooling rate of the brain are systematically investigated. (1) Pennes H. H., “Analysis of tissue and arterial blood temperature in the resting forearm.” J. Appl. Physiol. 1: 93-122, 1948. (2) Wissler E. H., “Steady-state temperature distribution in man”, J. Appl. Physiol., 16: 764-740, 1961. (3) Stolwick J. A. J., “Mathematical model of thermoregulation” in “Physiological and behavioral temperature regulation”, edited by J. D. Hardy, A. P. Gagge and A. J. Stolwijk, Charles C. Thomas Publisher, Springfiels, Ill., 703-721, 1971. (4) Werner J., Webb P., “A six-cylinder model of human thermoregulation for general use on personal computers”, Ann. Physiol. Anthrop., 12(3): 123-134, 1993.

What is the Integral in Integral Education? From Progressive Pedagogy to Integral Pedagogy

Directory of Open Access Journals (Sweden)

Tom Murray

2009-06-01

Full Text Available Integrally-informed educational approaches have much in common withprogressive (including reform, alternative, holistic, and transformative approaches, andshare many of the same values. One function of the integral approach is to provide anoverarching model within which to coordinate different progressive methods. Thoughintegral adds much more than that, descriptions of integral education sometimes soundlike progressive educational principles recast with new terminology. This essay attemptsto clarify what the integral approach adds over and above progressive educationaltheories. After an overview of progressive pedagogical principles, the integral approachis discussed in terms of integral as a model, a method, a community, and a developmentalstage. Integral as a type of consciousness or developmental level is elaborated upon asconsisting of construct-awareness, ego-awareness, relational-awareness, and systemawareness,all important to the educational process. Finally, challenges and supportsystems for realizing integral education are discussed.

IntPath--an integrated pathway gene relationship database for model organisms and important pathogens.

Science.gov (United States)

Zhou, Hufeng; Jin, Jingjing; Zhang, Haojun; Yi, Bo; Wozniak, Michal; Wong, Limsoon

2012-01-01

Pathway data are important for understanding the relationship between genes, proteins and many other molecules in living organisms. Pathway gene relationships are crucial information for guidance, prediction, reference and assessment in biochemistry, computational biology, and medicine. Many well-established databases--e.g., KEGG, WikiPathways, and BioCyc--are dedicated to collecting pathway data for public access. However, the effectiveness of these databases is hindered by issues such as incompatible data formats, inconsistent molecular representations, inconsistent molecular relationship representations, inconsistent referrals to pathway names, and incomprehensive data from different databases. In this paper, we overcome these issues through extraction, normalization and integration of pathway data from several major public databases (KEGG, WikiPathways, BioCyc, etc). We build a database that not only hosts our integrated pathway gene relationship data for public access but also maintains the necessary updates in the long run. This public repository is named IntPath (Integrated Pathway gene relationship database for model organisms and important pathogens). Four organisms--S. cerevisiae, M. tuberculosis H37Rv, H. Sapiens and M. musculus--are included in this version (V2.0) of IntPath. IntPath uses the "full unification" approach to ensure no deletion and no introduced noise in this process. Therefore, IntPath contains much richer pathway-gene and pathway-gene pair relationships and much larger number of non-redundant genes and gene pairs than any of the single-source databases. The gene relationships of each gene (measured by average node degree) per pathway are significantly richer. The gene relationships in each pathway (measured by average number of gene pairs per pathway) are also considerably richer in the integrated pathways. Moderate manual curation are involved to get rid of errors and noises from source data (e.g., the gene ID errors in WikiPathways and

Using a classic paper by Robin Fahraeus and Torsten Lindqvist to teach basic hemorheology

DEFF Research Database (Denmark)

Toksvang, Linea Natalie; Berg, Ronan M G

2013-01-01

"The viscosity of the blood in narrow capillary tubes" by Robin Fåhraeus and Torsten Lindqvist (Am J Physiol 96: 562-568, 1931) can be a valuable opportunity for teaching basic hemorheological principles in undergraduate cardiovascular physiology. This classic paper demonstrates that a progressive...

TMFunction data: 662 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... -26.4 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 669 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... -34.7 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 670 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... -41.3 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

TMFunction data: 663 [TMFunction[Archive

Lifescience Database Archive (English)

Full Text Available Lambert G, Forster IC, Stange G, Biber J, Murer H. J Gen Physiol. 1999 Nov;114(5):637-52 cysteine mutagenesis... -25.3 Electrogenic Activity (Ip) electrophysiological ... NPT2A_RAT (Q06496) Helix ... mutagenesis; phosphate transport; electrophysiology; Xenopus laevis oocyte

note on variable incubation period within a clutch of eggs

African Journals Online (AJOL)

Compo Biochem. Physiol. 53A: 1-6. MENDELSOHN, 1. M., BIGOS, H. C. & LEDGER, 1. A. In press. The biology of the black-shouldered. NOTE ON VARIABLE. INCUBATION PERIOD WITHIN A. CLUTCH OF EGGS OF THE. LEOPARD TORTOISE. (GEOCHELONE P ARDALIS). (CHELONIA: CRYPTODIRA: TESTUDINIDAE).

Khan et al., Afr J Tradit Complement Altern Med. (2013) 10(3):436 ...

African Journals Online (AJOL)

AJTCAM

The effects of Duranta repens fruits were investigated on H2O2 induced .... Data were analyzed by one-way ANOVA and then post-hoc comparison (LSD test) by using ..... brain. J. Physiol. Pharmacol., 56: 23-36. 27. Shahat, A.A., Nazif, N.M., ...

Microfluidic monitoring of programmed cell death in living plant seed tissue

DEFF Research Database (Denmark)

Mark, Christina; Heiskanen, Arto; Zor, Kinga

highly specific responses to the phytohormones gibberellic acid and abscisic acid. Combined with the increasing usage as a model for studying plant protein secretion, these properties make the aleurone layer ideal for maintenance in a microfluidics system (Fath, Angelika, et al., (2001), Plant Physiol...

Physiological status of Drosophila suzukii (Diptera: Drosophilidae) affects their response to attractive odours

Science.gov (United States)

A comprehensive understanding of the biology of the invasive pest, Drosophila suzukii, is critical for the development of effective management strategies. Trapping is one technique used both for detection and control, however the efficacy of trapping can vary depending on the target insect’s physiol...

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African Journals Online (AJOL)

.; Mann, K.; Roitman, J.N.; Yatskievych, G.;. Proksch, M.; Proksch, P. J. Plant. Physiol., 1987, 131, 37. Adityachaudhury, N.; Rose, P.C. Int. Symp. Chem. Nat. Prod., 1978, 2, 183,. Berdwaj, D.K.; Jain, R.K.: Munjal, A.; Prasher, M. Indian J. Chem., ...

Maltase-glucoamylase: Mucosal regulator of prandial starch glucogenesis and complementary hepatic gluconeogenesis of mice

Science.gov (United States)

It was hypothesized that the slower rate of starch digestion by residual sucraseisomaltase (Si) maltase failed to fully regulate gluconeogenesis. In the present study the rate of gluconeogenesis was measured directly (J Appl Physiol 104: 944-951, 2008) and compared with exogenous glucose derived fro...

Micromonospora is a normal occupant of actinorhizal nodules

Indian Academy of Sciences (India)

2013-10-01

Oct 1, 2013 ... substitutions with Kimura's two-parameter method (Kimura. 1980), and ..... fixation in the management of temperate forests (eds) JC. Gordon, CT Wheeler ... Genilloud O 2012 Genus I. Micromonospora; in Bergey's manual of systematic .... Production and specificity of root hair deformation factor(s). Physiol.

International Symposium on the Biology and Management of Aquatic Plants Held in Daytona Beach, Florida on 12-16 July 1992, Volume 31

Science.gov (United States)

1993-01-01

antioxidative transgenic plants overexpressing peroxidase. Plant Physiol 96.577- defense systems in early leaf growth. J. Plant Growth Regul. 10- 187- 583...S. A. 1986. Effects of dalapon and glyphosate on Imperata cylindrica (L) Beauv. at different growth stages. MARDI Res. Bull. achieved. In addition

Power Systems Integration Laboratory | Energy Systems Integration Facility

Science.gov (United States)

| NREL Power Systems Integration Laboratory Power Systems Integration Laboratory Research in the Energy System Integration Facility's Power Systems Integration Laboratory focuses on the microgrid applications. Photo of engineers testing an inverter in the Power Systems Integration Laboratory

Identificação do dano induzido por fadiga e cura de micro trincas em compósitos cerâmicos particulados, voltados à aplicação em pavimentos flexíveis Fatigue damage induced and healing identification in particulate ceramic composites for application in flexible pavings

Directory of Open Access Journals (Sweden)

F. R. G. Nunes

2009-12-01

Full Text Available Um dos grandes defeitos ocorrentes no pavimento, ao longo de sua vida útil, é o trincamento por fadiga. Este problema, em geral, se inicia na base do revestimento asfáltico e se propaga para a sua superfície. A caracterização das misturas asfálticas, realizada comumente no Brasil, é baseada no número de ciclos que causam a ruptura no ensaio de fadiga. No entanto, tal número não é um parâmetro mecânico, podendo variar para diferentes condições de contorno. O objetivo do presente artigo é identificar parâmetros mecânicos, referentes ao trincamento por fadiga, do compósito asfáltico com agregado sintético de argila calcinada (ASAC. Para tanto, foi utilizado um modelo viscoelástico de dano contínuo, fundamentado em trabalhos de Shapery, Kim e Lee. Os resultados com o compósito estudado (ASAC mostraram que a perda de rigidez, baseada em uma variável interna de estado, pode ser um critério de fadiga; que o ensaio pode ser realizado para um nível de tensão; a cura de microtrincas durante os períodos de não solicitação da estrutura.One of the major distresses in flexible pavings, throughout its useful life, is the fatigue cracking. This problem, in general, initiates in the base of the asphalt layer and propagates for its surface. The characterization of the asphalt mixtures, carried out in Brazil, is based on the number of cycles that cause the rupture in the fatigue test. However, such number is not a mechanical parameter, varying for different boundary conditions. The objective of the present article is to identify mechanical parameters, referring fatigue cracking, of the asphalt composite with synthetic calcinated clay aggregates (SCCA. To this end, a continuum damage viscoelastic model was used based works from Shapery, Kim and Lee. The results with the composite studied (SCCA had shown: that the loss of rigidity, based on an internal state variable, can be a fatigue criterion; that the test can be carried through

Integral-preserving integrators

International Nuclear Information System (INIS)

McLaren, D I; Quispel, G R W

2004-01-01

Ordinary differential equations having a first integral may be solved numerically using one of several methods, with the integral preserved to machine accuracy. One such method is the discrete gradient method. It is shown here that the order of the method can be bootstrapped repeatedly to higher orders of accuracy. The method is illustrated using the Henon-Heiles system. (letter to the editor)

[Integrity].

Science.gov (United States)

Gómez Rodríguez, Rafael Ángel

2014-01-01

To say that someone possesses integrity is to claim that that person is almost predictable about responses to specific situations, that he or she can prudentially judge and to act correctly. There is a closed interrelationship between integrity and autonomy, and the autonomy rests on the deeper moral claim of all humans to integrity of the person. Integrity has two senses of significance for medical ethic: one sense refers to the integrity of the person in the bodily, psychosocial and intellectual elements; and in the second sense, the integrity is the virtue. Another facet of integrity of the person is la integrity of values we cherish and espouse. The physician must be a person of integrity if the integrity of the patient is to be safeguarded. The autonomy has reduced the violations in the past, but the character and virtues of the physician are the ultimate safeguard of autonomy of patient. A field very important in medicine is the scientific research. It is the character of the investigator that determines the moral quality of research. The problem arises when legitimate self-interests are replaced by selfish, particularly when human subjects are involved. The final safeguard of moral quality of research is the character and conscience of the investigator. Teaching must be relevant in the scientific field, but the most effective way to teach virtue ethics is through the example of the a respected scientist.

Two competitive enzyme immunoassays for the detection of IgG class antibodies to hepatitis a antigen

Directory of Open Access Journals (Sweden)

Claudia Lamarca Vitral

1991-06-01

Full Text Available Two competitive enzyme immunoassays (EIA techniques were developed: in the first (COMP-1, test sera were added together with HAV antigen on anti-HAV IgG-coated wells followed by an anti-HA VHRP conjugate; in the second (COMP-2, test sera and anti-HA VHRP conjugate competed for HAV epitopes previously adsorbed to anti-HA V IgG-coated wells. Both procedures used tetramethylbenzidine (TMB as a substrate. Both competitive tests were shown to be reproducible and suitable for routine diagnosis and research purposes.Foram desenvolvidos dois ensaios imunoenzimáticos (EIA competitivos: no primeiro (COMP-1 colocou-se numa placa sensibilizada com anti-HAVIgG as amostras teste juntamente como antígeno HA Vea seguir o conjugado anti-HA VHRP; no segundo (COMP-2, as amostras teste e o conjugado anti-HAV HRP competem pelos epitopos do antígeno HAV previamente absorvido na placa sensibilizada do anti-HAV IgG. O substrato utilizado foi tetrametilbenzidina (TMB. Ambas as técnicas mostraram ser produtíveis e aplicáveis para fins de diagnóstico e pesquisa.

Yield Stress Model for Molten Composition B-3

Science.gov (United States)

Davis, Stephen; Zerkle, David

2017-06-01

Composition B-3 (Comp B-3) is a melt-castable explosive composed of 60/40 wt% RDX/TNT (hexahydro-1,3,5-trinitro-1,3,5-triazine/2,4,6-trinitrotoluene). During casting operations thermal conditions are controlled which along with the low melting point of TNT and the insensitivity of the mixture to external stimuli leading to safe use. Outside these standard operating conditions a more rigorous model of Comp B-3 rheological properties is necessary to model thermal transport as Comp B-3 evolves from quiescent solid through vaporization/decomposition upon heating. One particular rheological phenomena of interest is Bingham plasticity, where a material behaves as a quiescent solid unless a sufficient load is applied, resulting in fluid flow. In this study falling ball viscometer data is used to model the change in Bingham plastic yield stresses as a function of RDX particle volume fraction; a function of temperature. Results show the yield stress of Comp B-3 (τy) follows the expression τy = B ϕ -ϕc N , where Φ and Φc are the volume fraction of RDX and a critical volume fraction, respectively and B and N are experimentally evaluated constants.

Comparative proteomic analysis of normal and collagen IX null mouse cartilage reveals altered extracellular matrix composition and novel components of the collagen IX interactome.

Science.gov (United States)

Brachvogel, Bent; Zaucke, Frank; Dave, Keyur; Norris, Emma L; Stermann, Jacek; Dayakli, Münire; Koch, Manuel; Gorman, Jeffrey J; Bateman, John F; Wilson, Richard

2013-05-10

Collagen IX is an integral cartilage extracellular matrix component important in skeletal development and joint function. Proteomic analysis and validation studies revealed novel alterations in collagen IX null cartilage. Matrilin-4, collagen XII, thrombospondin-4, fibronectin, βig-h3, and epiphycan are components of the in vivo collagen IX interactome. We applied a proteomics approach to advance our understanding of collagen IX ablation in cartilage. The cartilage extracellular matrix is essential for endochondral bone development and joint function. In addition to the major aggrecan/collagen II framework, the interacting complex of collagen IX, matrilin-3, and cartilage oligomeric matrix protein (COMP) is essential for cartilage matrix stability, as mutations in Col9a1, Col9a2, Col9a3, Comp, and Matn3 genes cause multiple epiphyseal dysplasia, in which patients develop early onset osteoarthritis. In mice, collagen IX ablation results in severely disturbed growth plate organization, hypocellular regions, and abnormal chondrocyte shape. This abnormal differentiation is likely to involve altered cell-matrix interactions but the mechanism is not known. To investigate the molecular basis of the collagen IX null phenotype we analyzed global differences in protein abundance between wild-type and knock-out femoral head cartilage by capillary HPLC tandem mass spectrometry. We identified 297 proteins in 3-day cartilage and 397 proteins in 21-day cartilage. Components that were differentially abundant between wild-type and collagen IX-deficient cartilage included 15 extracellular matrix proteins. Collagen IX ablation was associated with dramatically reduced COMP and matrilin-3, consistent with known interactions. Matrilin-1, matrilin-4, epiphycan, and thrombospondin-4 levels were reduced in collagen IX null cartilage, providing the first in vivo evidence for these proteins belonging to the collagen IX interactome. Thrombospondin-4 expression was reduced at the mRNA level

An Eye Oximeter for Combat Casualty Care

Science.gov (United States)

1999-12-01

function and to their vulnerability to ischemia: A com- mentary based on studies on retina," Gin. /. Physiol. Pharma - col. 70, S158-164 (1992). T. E...Huntsville Provided tutoring in freshman level Mechanics and Electricity and Magnetism courses and laboratories. • Taught Advanced Placement (AP) Physics

Nigerian Journal of Physiological Sciences: Editorial Policies

African Journals Online (AJOL)

Focus and Scope. Nigerian Journal of Physiological Sciences (Niger. J. Physiol. Sci.) is a biannual publication of the Physiological Society of Nigeria. It covers diverse areas of research in physiological sciences, publishing reviews in current research areas and original laboratory and clinical research in physiological ...

Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia

DEFF Research Database (Denmark)

Larsen, Steen; Scheede-Bergdahl, Celena; Whitesell, Thomas

2015-01-01

the groups when evaluating the more physiol. complex I and II linked OXPHOS capacity. These findings indicate that chronic hyperglycemia results in an elevated intrinsic mitochondrial respiratory capacity in both soleus and, at varying degree, plantaris muscle, findings that are consistent with human T1DM...

Nigerian Journal of Physiological Sciences

African Journals Online (AJOL)

Nigerian Journal of Physiological Sciences (Niger. J. Physiol. Sci.) is a biannual publication of the Physiological Society of Nigeria. It covers diverse areas of research in physiological sciences, publishing reviews in current research areas and original laboratory and clinical research in physiological sciences. Other websites ...

Oral glucose intake inhibits hypothalamic neuronal activity more effectively than glucose infusion

NARCIS (Netherlands)

Smeets, P.A.M.; Vidarsdottir, S.; Graaf, de C.; Stafleu, A.; Osch, M.J.P.; Viergever, M.A.; Pijl, H.; Grond, van der J.

2007-01-01

Oral glucose intake inhibits hypothalamic neuronal activity more effectively than glucose infusion. Am J Physiol Endocrinol Metab 293: E754-E758, 2007. First published June 12, 2007; doi:10.1152/ajpendo.00231.2007. - We previously showed that hypothalamic neuronal activity, as measured by the blood

Dynamic adaptation of cardiac baroreflex sensitivity to prolonged exposure to microgravity: data from a 16-day spaceflight

NARCIS (Netherlands)

Di Rienzo, Marco; Castiglioni, Paolo; Iellamo, Ferdinando; Volterrani, Maurizio; Pagani, Massimo; Mancia, Giuseppe; Karemaker, John M.; Parati, Gianfranco

2008-01-01

Di Rienzo M, Castiglioni P, Iellamo F, Volterrani M, Pagani M, Mancia G, Karemaker JM, Parati G. Dynamic adaptation of cardiac baroreflex sensitivity to prolonged exposure to microgravity: data from a 16-day spaceflight. J Appl Physiol 105: 1569-1575, 2008. First published August 28, 2008;

Monosodium Glutamate Toxicity

African Journals Online (AJOL)

Dr Olaleye

The brain is reportedly sensitive to monosodium glutamate (MSG) toxicity via oxidative stress. Sida acuta leaf ethanolic .... wherein the right hemisphere, was preserved for histology and fixed in 10% ... Biochemical Assays: The left hemisphere of the brain samples was ...... development in male and female rats. Exp Physiol.

Operational Based Vision Assessment Research: Depth Perception

Science.gov (United States)

2014-11-01

Potential hazards of viewing 3-D stereoscopic television, cinema and computer games: a review. Ophthalmic Physiol Opt 2011; 31:111-22. 75. Watt SJ...the 2012 Interservice/Industry Training, Simulation, and Education Conference (I/ITSEC); 2012 Dec 3-6; Orlando, FL. 82. Blake R, Fox R. The

Prevalence of central sleep apnea during continous positive airway pressure (CPAP) titration in subjects with obstructive sleep apnea syndrome at an altitude of 2640 m.

Science.gov (United States)

Bazurto Zapata, Maria Angelica; Martinez-Guzman, William; Vargas-Ramirez, Leslie; Herrera, Karen; Gonzalez-Garcia, Mauricio

2015-03-01

The occurrence of central apneas when applying positive pressure (CPAP) to patients with obstructive sleep apnea syndrome (OSAS) is called complex sleep apnea (CompSA). This causes poor adherence to CPAP and persistence of symptoms. In Bogota, a city located at an altitude of 2640 m above sea level, chronic hypoxemia can generate certain instability of the respiratory system during sleep which could increase the presence of central apnea. The aim was to establish the prevalence of central apnea (central apnea index >5/h) in adults with moderate or severe OSAS during CPAP titration, and the factors associated with this. Patients over 18 years old with OSAS were referred to the Fundacion Neumologica Colombiana Sleep Center, from January 2008 to June 2010. Polysomnogram (PSG) for CPAP titration was performed according to the American Academy of Sleep Medicine criteria. The prevalence was calculated and the clinical and baseline PSG factors associated with the CompSA were analyzed. We included 988 patients, 58% men. CompSA prevalence was 11.6%. Factors associated with CompSA were: central apneas in the baseline PSG (OR: 5.34 [3.49-8.16]), history of heart failure (OR: 2.53 [1.58-4.07]), and male sex (OR: 1.68 [1.06-2.69]). The prevalence of complex sleep apnea in Bogota (11.6%) was intermediate compared to the reported in lower altitudes. The factors associated with the development of CompSA were male sex, heart failure, and the presence of central apnea in the baseline PSG. Copyright © 2014 Elsevier B.V. All rights reserved.

Moxifloxacin in Pediatric Patients with Complicated Intra-Abdominal Infections: Results of the MOXIPEDIA Randomized Controlled Study.

Science.gov (United States)

Wirth, Stefan; Emil, Sherif G S; Engelis, Arnis; Digtyar, Valeri; Criollo, Margarita; DiCasoli, Carl; Stass, Heino; Willmann, Stefan; Nkulikiyinka, Richard; Grossmann, Ulrike

2018-01-18

This study was designed to evaluate primarily the safety and also the efficacy of moxifloxacin (MXF) in children with complicated intra-abdominal infections (cIAIs). In this multicenter, randomized, double-blind, controlled study, 451 pediatric patients aged 3 months to 17 years with cIAIs were treated with intravenous/oral MXF (N = 301) or comparator (COMP, intravenous ertapenem followed by oral amoxicillin/clavulanate; N = 150) for 5 to 14 days. Doses of MXF were selected based on the results of a Phase 1 study in pediatric patients (NCT01049022). The primary endpoint was safety, with particular focus on cardiac and musculoskeletal safety; clinical and bacteriological efficacy at test of cure were also investigated. The proportion of patients with adverse events (AEs) was comparable between the two treatment arms (MXF: 58.1% and COMP: 54.7%). The incidence of drug-related AEs was higher in the MXF arm than the COMP arm (14.3% and 6.7%, respectively). No cases of QTc interval prolongation-related morbidity or mortality were observed. The proportion of patients with musculoskeletal AEs was comparable between treatment arms; no drug-related events were reported. Clinical cure rates were 84.6% and 95.5% in the MXF and COMP arms, respectively, in patients with confirmed pathogen(s) at baseline. MXF treatment was well tolerated in children with cIAIs. However, a lower clinical cure rate was observed with MXF treatment compared with COMP. This study does not support a recommendation of MXF for children with cIAIs when alternative more efficacious antibiotics with better safety profile are available.

The Influence of Preprocessing Steps on Graph Theory Measures Derived from Resting State fMRI.

Science.gov (United States)

Gargouri, Fatma; Kallel, Fathi; Delphine, Sebastien; Ben Hamida, Ahmed; Lehéricy, Stéphane; Valabregue, Romain

2018-01-01

Resting state functional MRI (rs-fMRI) is an imaging technique that allows the spontaneous activity of the brain to be measured. Measures of functional connectivity highly depend on the quality of the BOLD signal data processing. In this study, our aim was to study the influence of preprocessing steps and their order of application on small-world topology and their efficiency in resting state fMRI data analysis using graph theory. We applied the most standard preprocessing steps: slice-timing, realign, smoothing, filtering, and the tCompCor method. In particular, we were interested in how preprocessing can retain the small-world economic properties and how to maximize the local and global efficiency of a network while minimizing the cost. Tests that we conducted in 54 healthy subjects showed that the choice and ordering of preprocessing steps impacted the graph measures. We found that the csr (where we applied realignment, smoothing, and tCompCor as a final step) and the scr (where we applied realignment, tCompCor and smoothing as a final step) strategies had the highest mean values of global efficiency (eg) . Furthermore, we found that the fscr strategy (where we applied realignment, tCompCor, smoothing, and filtering as a final step), had the highest mean local efficiency (el) values. These results confirm that the graph theory measures of functional connectivity depend on the ordering of the processing steps, with the best results being obtained using smoothing and tCompCor as the final steps for global efficiency with additional filtering for local efficiency.

Predictive parameters for selection of electronic tissue compensation radiotherapy in early-stage breast cancer patients after breast-conserving surgery.

Science.gov (United States)

Song, Yanbo; Zhang, Miao; Gan, Lu; Chen, Xiaopin; Zhang, Tao; Yue, Ning J; Goyal, Sharad; Haffty, Bruce; Ren, Guosheng

2016-05-31

Electronic tissue compensation (eComp) is an external beam planning technique allowing user to manually generate dynamic beam fluence to produce more uniform or modulated dose distribution. In this study, we compared the effectiveness between conventional three-dimensional conformal radiotherapy (3DCRT) and eComp for whole breast irradiation. 3DCRT and eComp planning techniques were used to generate treatment plans for 60 whole breast patients, respectively. The planning goal was to cover 95% of the planning target volume (PTV) with 95% of the prescription dose while minimizing doses to lung, heart, and skin. Comparing to 3DCRT plans, on the average, eComp treatment planning process was about 7 minutes longer, but resulted in lower lung V20Gy, lower mean skin dose, with similar heart dose. The benefits were more pronounced for larger breast patients. Statistical analyses were performed between critical organ doses and patient anatomic features, i.e., central lung distance (CLD), maximal heart distance (MHD), maximal heart length (MHL) and breast separation (BS) to explore any correlations and planning method selection. It was found that to keep the lung V20Gy lower than 20% and mean skin dose lower than 85% of the prescription dose, eComp was the preferred method for patients with more than 2.3 cm CLD or larger than 22.5 cm BS. The study results may be useful in providing a handy criterion in clinical practice allowing us to easily choose between different planning techniques to satisfy the planning goal with minimal increase in complexity and cost.

The Influence of Preprocessing Steps on Graph Theory Measures Derived from Resting State fMRI

Directory of Open Access Journals (Sweden)

Fatma Gargouri

2018-02-01

Full Text Available Resting state functional MRI (rs-fMRI is an imaging technique that allows the spontaneous activity of the brain to be measured. Measures of functional connectivity highly depend on the quality of the BOLD signal data processing. In this study, our aim was to study the influence of preprocessing steps and their order of application on small-world topology and their efficiency in resting state fMRI data analysis using graph theory. We applied the most standard preprocessing steps: slice-timing, realign, smoothing, filtering, and the tCompCor method. In particular, we were interested in how preprocessing can retain the small-world economic properties and how to maximize the local and global efficiency of a network while minimizing the cost. Tests that we conducted in 54 healthy subjects showed that the choice and ordering of preprocessing steps impacted the graph measures. We found that the csr (where we applied realignment, smoothing, and tCompCor as a final step and the scr (where we applied realignment, tCompCor and smoothing as a final step strategies had the highest mean values of global efficiency (eg. Furthermore, we found that the fscr strategy (where we applied realignment, tCompCor, smoothing, and filtering as a final step, had the highest mean local efficiency (el values. These results confirm that the graph theory measures of functional connectivity depend on the ordering of the processing steps, with the best results being obtained using smoothing and tCompCor as the final steps for global efficiency with additional filtering for local efficiency.

The Influence of Preprocessing Steps on Graph Theory Measures Derived from Resting State fMRI

Science.gov (United States)

Gargouri, Fatma; Kallel, Fathi; Delphine, Sebastien; Ben Hamida, Ahmed; Lehéricy, Stéphane; Valabregue, Romain

2018-01-01

Resting state functional MRI (rs-fMRI) is an imaging technique that allows the spontaneous activity of the brain to be measured. Measures of functional connectivity highly depend on the quality of the BOLD signal data processing. In this study, our aim was to study the influence of preprocessing steps and their order of application on small-world topology and their efficiency in resting state fMRI data analysis using graph theory. We applied the most standard preprocessing steps: slice-timing, realign, smoothing, filtering, and the tCompCor method. In particular, we were interested in how preprocessing can retain the small-world economic properties and how to maximize the local and global efficiency of a network while minimizing the cost. Tests that we conducted in 54 healthy subjects showed that the choice and ordering of preprocessing steps impacted the graph measures. We found that the csr (where we applied realignment, smoothing, and tCompCor as a final step) and the scr (where we applied realignment, tCompCor and smoothing as a final step) strategies had the highest mean values of global efficiency (eg). Furthermore, we found that the fscr strategy (where we applied realignment, tCompCor, smoothing, and filtering as a final step), had the highest mean local efficiency (el) values. These results confirm that the graph theory measures of functional connectivity depend on the ordering of the processing steps, with the best results being obtained using smoothing and tCompCor as the final steps for global efficiency with additional filtering for local efficiency. PMID:29497372

Transport parameter estimation from lymph measurements and the Patlak equation.

Science.gov (United States)

Watson, P D; Wolf, M B

1992-01-01

Two methods of estimating protein transport parameters for plasma-to-lymph transport data are presented. Both use IBM-compatible computers to obtain least-squares parameters for the solvent drag reflection coefficient and the permeability-surface area product using the Patlak equation. A matrix search approach is described, and the speed and convenience of this are compared with a commercially available gradient method. The results from both of these methods were different from those of a method reported by Reed, Townsley, and Taylor [Am. J. Physiol. 257 (Heart Circ. Physiol. 26): H1037-H1041, 1989]. It is shown that the Reed et al. method contains a systematic error. It is also shown that diffusion always plays an important role for transmembrane transport at the exit end of a membrane channel under all conditions of lymph flow rate and that the statement that diffusion becomes zero at high lymph flow rate depends on a mathematical definition of diffusion.

Energy Systems Integration Laboratory | Energy Systems Integration Facility

Science.gov (United States)

| NREL Integration Laboratory Energy Systems Integration Laboratory Research in the Energy Systems Integration Laboratory is advancing engineering knowledge and market deployment of hydrogen technologies. Applications include microgrids, energy storage for renewables integration, and home- and station

Energy Systems Integration Facility Videos | Energy Systems Integration

Science.gov (United States)

Facility | NREL Energy Systems Integration Facility Videos Energy Systems Integration Facility Integration Facility NREL + SolarCity: Maximizing Solar Power on Electrical Grids Redefining What's Possible for Renewable Energy: Grid Integration Robot-Powered Reliability Testing at NREL's ESIF Microgrid

Formación en emprendimiento en estudiantes de la carrera de administración de empresas en la Universidad Pública de Popayán = Entrepreneurial formation of business administration students of a Public Institution in Popayan, Colombia

Directory of Open Access Journals (Sweden)

Zamanda Correa Correa

2011-08-01

Les établissements d’enseignement encouragent l’esprit d’entreprise par le biais de l’éducation pour stimuler la création d’entreprises et la gestion d’affaires, mais ne forment en entrepreneuriat et n’incluent donc pas dans leurs programmes le développement des compétences propres aux entrepreneurs à succès. Pour former des étudiants entreprenants, il conviendrait de renforcer également le développement des modes de pensée et de comportement des entrepreneurs comme de leurs compétences (Kirby, 2004; OCDE, 2002 ; Sarasvathy 2001 ; (Gibb, 2005. Cet article examine les compétences entrepreneuriales à développer chez des étudiants d’administration d’entreprise d’une université publique. La méthodologie aborde différentes conceptions méthodologiques, quantitatives et qualitatives qui consistent en deux études: une analytique et une descriptive. Pour l’étude descriptive on effectue une description des principales compétences entrepreneuriales de la littérature spécialisée, cette analyse des données est effectuée avec le logiciel de statistiques SSPS 15,0 (par période et pays qui établit les vingt compétences les plus nommées dans la littérature spécialisée : les « risques calculés » apparaissant à hauteur de 70,3 %, l’initiative/autonomie à 59 ,5 % et l’innovation et créativité à 56,8 %. Les compétences en marketing, en logique mathématique et en sens de l’humour (2,7 %, se voient attribuées les dernières places du classement. La technique utilisée pour le consensus de l’étude analytique est la méthode Delphi. Une fois obtenues les réponses des experts, celles-ci sont traitées pour déterminer leur niveau de cohérence. Cette technique a permis d’identifier les compétences entrepreneuriales à développer chez les élèves d’administration d´entreprises recherchant pour leur formation universitaire la création d’une atmosphère favorable : initiative/autonomie, innovation

Glucosamine but not ibuprofen alters cartilage turnover in osteoarthritis patients in response to physical training

DEFF Research Database (Denmark)

Petersen, Susanne Germann; Saxne, T; Heinegard, D

2010-01-01

OBJECTIVE: To investigate changes in levels of serum cartilage oligomeric matrix protein (COMP) and urine c-telopeptide of type-2 collagen (CTX-II) as markers for cartilage turnover in patients with osteoarthritis (OA) of the knee, in response to muscle strength training in combination with treat......OBJECTIVE: To investigate changes in levels of serum cartilage oligomeric matrix protein (COMP) and urine c-telopeptide of type-2 collagen (CTX-II) as markers for cartilage turnover in patients with osteoarthritis (OA) of the knee, in response to muscle strength training in combination......). RESULTS: All three groups increased their muscle strength following 12 weeks of strength training (Preduced in the glucosamine-treated group after the training period (P=0.012), whereas they did not change in the two other groups. Glucosamine reduced COMP statistically...

Grid Integration Webinars | Energy Systems Integration Facility | NREL

Science.gov (United States)

Grid Integration Webinars Grid Integration Webinars Watch presentations from NREL analysts on various topics related to grid integration. Wind Curtailment and the Value of Transmission under a 2050 renewable curtailment under these high wind scenarios. Text Version Grid Integration Webinar: Exploring

Comportamento termomecânico de compósitos ativos preparados com nanocompósitos epóxi/argila organofílica e fios de liga Ni-Ti com memória de forma Thermomechanical behavior of active composites prepared with epoxy/organoclay nanocomposites and Ni-Ti shape memory alloy wires

Directory of Open Access Journals (Sweden)

Artur S. C. Leal

2012-01-01

Full Text Available Neste trabalho, nanocompósitos epóxi/argila organofílica foram selecionados como matriz por apresentarem valores de temperatura de transição vítrea (Tg e estabilidade térmica suficientemente alta para que fios de uma liga com memória de forma (LMF possam ser incorporados. Para tanto, quatro frações volumétricas de fios LMF de Ni-Ti (1,55, 2,56, 3,57 e 4,54% foram embebidas na matriz epoxídica diglicidil éter do bisfenol-A (DGEBA, reticulada com a amina aromática 4,4’-diamino difenil sulfona (DDS contendo 1 pcr da argila bentonita purificada organofiliada (APOC. A formação do nanocompósito foi confirmada por análise de difração de raio X, enquanto a transformação de fase dos fios de Ni-Ti foi determinada por análise dinâmico-mecânica (DMA. As amostras dos compósitos ativos preparados a partir da matriz de nanocompósito e fios de Ni-Ti foram caracterizadas principalmente por DMA. De acordo com os resultados obtidos foi constatada uma recuperação do módulo de armazenamento do compósito ativo durante o aquecimento na faixa de transformação de fase dos fios de Ni-Ti quando a fração volumétrica foi mantida em torno de 3,5%.In this work, epoxy/organoclay nanocomposites were selected as matrix for presenting high enough glass transition temperature (Tg and thermal stability values in order to be incorporated in shape memory alloys (SMA. Four volume fractions of SMA wires containing Ni-Ti (1.55, 2.56, 3.57 and 4.54% were embedded in diglycidyl ether of bisphenol A (DGEBA, cured with the aromatic amine 4,4’-diamino diphenyl sulfone (DDS and containing 1 phr of purified organobentonite (APOC. The formation of nanocomposite was confirmed by X ray diffraction analysis, while the phase transformation of Ni-Ti wires was determined by dynamic mechanical analysis (DMA. Samples of the active composites prepared from nanocomposite matrix and Ni-Ti wires were mainly characterized by DMA. A recovery of the storage modulus of

Avaliações térmica e reológica da matriz termoplástica PEKK utilizada em compósitos aeronáuticos Thermal and rheological evaluation of PEKK thermoplastic matrix for aeronautical application

Directory of Open Access Journals (Sweden)

Rogério L. Mazur

2008-09-01

Full Text Available A matriz termoplástica semicristalina PEKK (poli (éter-cetona-cetona tem recebido nos últimos anos uma atenção crescente pelas indústrias aeronáutica e espacial, no processamento de compósitos poliméricos avançados. As características de elevados valores de temperatura de transição vítrea, de resistência mecânica e de módulo de elasticidade, baixa absorção de umidade, excelente resistência a variações de condições climáticas, combinadas a uma relativa baixa massa específica faz do PEKK uma atrativa opção para uma variedade de aplicações, principalmente na área aeronáutica. O objetivo deste trabalho é correlacionar parâmetros térmicos e reológicos do PEKK, por meio das técnicas de calorimetria exploratória diferencial (DSC, termogravimetria (TG e reológica, no estabelecimento de um ciclo térmico de processamento, a ser utilizado na obtenção de laminados de PEKK com fibras de carbono, pela técnica de moldagem por compressão a quente de compósitos termoplásticos. Os resultados obtidos mostram que o PEKK apresenta um excelente balanço de propriedades, tais como elevada temperatura de transição vítrea (153-156 °C e moderadas temperaturas de processamento, localizadas entre suas temperaturas de fusão (310-325 °C e de degradação (352-366 °C, principalmente quando comparado com as matrizes atualmente mais utilizadas no setor aeronáutico: o PEEK (poli (éter-éter-cetona; o PEI (poli (éter-imida e o PPS(poli(sulfona. A partir dos resultados térmicos e reológicos obtidos estabeleceu-se um ciclo térmico a ser utilizado no processamento de laminados PEKK/fibras de carbono pelo uso da moldagem por compressão a quente.Semi-crystalline PEKK thermoplastic matrix used in advanced polymeric composites have received a lot of interest for aerospace application in the last years. The higher glass transition temperature, high strength and stiffness, low moisture absorption, excellent environmental

Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats

NARCIS (Netherlands)

Koeners, Maarten P.; Wesseling, Sebastiaan; Ulu, Arzu; Lopez Sepulveda, Rocio; Morisseau, Christophe; Braam, Branko; Hammock, Bruce D.; Joles, Jaap A.

Koeners MP, Wesseling S, Ulu A, Sepulveda RL, Morisseau C, Braam B, Hammock BD, Joles JA. Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. Am J Physiol Endocrinol Metab 300: E691-E698, 2011. First published January 25, 2011; doi:

Long-term mannitol-induced osmotic stress leads to stomatal ...

African Journals Online (AJOL)

GREGORY

2010-09-13

Sep 13, 2010 ... elasticity and solute adjustment in two Acacia nilotica subspecies. Physiol. Plant, 93: 217-224. Navarro A, Banon S, Olmos E, Sahchez-Blanco MJ (2007). Effect of sodium chloride on water potential components, hydraulic conductivity, gas exchange and leaf ultrastructure of Arbutus unedo plants. Plant Sci.

Thyroid Hormone Changes during Military Field Operations: Effects of Cold Exposure in the Arctic.

Science.gov (United States)

1991-12-20

reasons; however, they primarily appear related to the hypocaloric states induced by a negative energy balance, stress reactivity of the endocrine...physical strain and sleep deprivation, and the influence of a high calorie diet . Eur J Appl Physiol 49:343-348. 17. Opstad PK, Aakvaag A (1983). The

Massive weight loss-induced mechanical plasticity in obese gait

NARCIS (Netherlands)

Hortobagyi, Tibor; Herring, Cortney; Pories, Walter J.; Rider, Patrick; DeVita, Paul

2011-01-01

Hortobagyi T, Herring C, Pories WJ, Rider P, DeVita P. Massive weight loss-induced mechanical plasticity in obese gait. J Appl Physiol 111: 1391-1399, 2011. First published August 18, 2011; doi:10.1152/japplphysiol.00291.2011.-We examined the hypothesis that metabolic surgery-induced massive weight

A Study on the Gastrointestinal Hormones and the Gastric Acid Secretion during Physical Stress in Man,

Science.gov (United States)

1983-12-15

histological signs of hypo- activity during starvation (147), the severe sleep deprivation contri- butes probably most to the hypersecretion of...damaged as in gastritis (35). REFERENCES Waldum et al. (36) have shown a positive cor- 1. Brown OH. Levine ML. Lipkin. M Am J Physiol relation between the

Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects

NARCIS (Netherlands)

Korstanje, Ron; Desai, Jigar; Lazar, Gloria; King, Benjamin; Rollins, Jarod; Spurr, Melissa; Joseph, Jamie; Kadambi, Sindhuja; Li, Yang; Cherry, Allison; Matteson, Paul G.; Paigen, Beverly; Millonig, James H.

Korstanje R, Desai J, Lazar G, King B, Rollins J, Spurr M, Joseph J, Kadambi S, Li Y, Cherry A, Matteson PG, Paigen B, Millonig JH. Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects. Physiol Genomics 35:

Thermoregulatory, Behavioral, and Metabolic Responses to Heatstroke in a Conscious Mouse Model

Science.gov (United States)

2010-04-28

endogenous mechanisms are protective in promoting recovery in this syndrome. Clearly, our understanding of the physiolog- ical mechanisms of Tc...Behav 52: 1133–1139, 1992. 15. Kluger MJ. Fever: role of pyrogens and cryogens. Physiol Rev 71: 93–127, 1991. 16. Kurz A, Sessler DI, Tayefeh R

Symmetric positive differential equations and first order hyperbolic systems

International Nuclear Information System (INIS)

Tangmanee, S.

1981-12-01

We prove that under some conditions the first order hyperbolic system and its associated mixed initial boundary conditions considered, for example, in Kreiss (Math. Comp. 22, 703-704 (1968)) and Kreiss and Gustafsson (Math. Comp. 26, 649-686 (1972)), can be transformed into a symmetric positive system of P.D.E.'s with admissible boundary conditions of Friedrich's type (Comm. Pure Appl. Math 11, 333-418 (1958)). (author)

Integrated project delivery : The designer as integrator

NARCIS (Netherlands)

Wamelink, J.W.F.; Koolwijk, J.S.J.; van Doorn, A.J.

2012-01-01

Process innovation related to integrated project delivery is an important topic in the building industry. Studies on process innovation through the use of integrated contracts usually focus on contractors, and particularly on the possibility of forward integration into the building process. Three

Integrity and the Value of an Integrated Self

NARCIS (Netherlands)

Archer, Alfred

What is integrity and why is it valuable? One account of the nature of integrity, proposed by John Cottingham (2010) amongst others, is The Integrated Self View. On this account integrity is a formal relation of coherence between various aspects of a person. One problem that has been raised against

Integrated test schedule for buried waste integrated demonstration

International Nuclear Information System (INIS)

Brown, J.T.; McDonald, J.K.

1992-05-01

The Integrated Test Schedule incorporates the various schedules the Buried Waste Integrated Demonstration (BWID) supports into one document. This document contains the Federal Facilities Agreement and Consent Order schedules for the Idaho National Engineering Laboratory, Hanford Reservation, Oak Ridge Reservation, and Fernald Environmental Materials Center. Included in the Integrated Test Schedule is the Buried Waste Integrated Demonstration ''windows of opportunity'' schedule. The ''windows of opportunity'' schedule shows periods of time in which Buried Waste Integrated Demonstration Program-sponsored technology demonstrations could support key decisions in the Federal Facilities Agreement and Consent Order. Schedules for the Buried Waste Integrated Demonstration-sponsored technology task plans are categorized by technology area and divided by current fiscal year and out-year. Total estimated costs for Buried Waste Integrated Demonstration-sponsored Technology Task Plans for FY-92 through FY-97 are $74.756M

COMP Superscalar, an interoperable programming framework

Science.gov (United States)

Badia, Rosa M.; Conejero, Javier; Diaz, Carlos; Ejarque, Jorge; Lezzi, Daniele; Lordan, Francesc; Ramon-Cortes, Cristian; Sirvent, Raul

2015-12-01

COMPSs is a programming framework that aims to facilitate the parallelization of existing applications written in Java, C/C++ and Python scripts. For that purpose, it offers a simple programming model based on sequential development in which the user is mainly responsible for (i) identifying the functions to be executed as asynchronous parallel tasks and (ii) annotating them with annotations or standard Python decorators. A runtime system is in charge of exploiting the inherent concurrency of the code, automatically detecting and enforcing the data dependencies between tasks and spawning these tasks to the available resources, which can be nodes in a cluster, clouds or grids. In cloud environments, COMPSs provides scalability and elasticity features allowing the dynamic provision of resources.

COMP Superscalar, an interoperable programming framework

Directory of Open Access Journals (Sweden)

Rosa M. Badia

2015-12-01

Full Text Available COMPSs is a programming framework that aims to facilitate the parallelization of existing applications written in Java, C/C++ and Python scripts. For that purpose, it offers a simple programming model based on sequential development in which the user is mainly responsible for (i identifying the functions to be executed as asynchronous parallel tasks and (ii annotating them with annotations or standard Python decorators. A runtime system is in charge of exploiting the inherent concurrency of the code, automatically detecting and enforcing the data dependencies between tasks and spawning these tasks to the available resources, which can be nodes in a cluster, clouds or grids. In cloud environments, COMPSs provides scalability and elasticity features allowing the dynamic provision of resources.

Spinal Cord Studies in the African Giant Rat (Cricetomys gambianus ...

African Journals Online (AJOL)

olayemitoyin

J. Physiol. Sci. 30 (2015) 025 – 032 www.njps.com.ng. Spinal Cord Studies in the African Giant Rat (Cricetomys gambianus .... Body and Spinal Cord measurements of the AGR (C. gambianus), Mean ±SEM ... the eighth cervical segment appeared circular in shape. ... other lumbar segments, sacral and coccygeal segments.

Ussing Chamber

NARCIS (Netherlands)

Westerhout, J.; Wortelboer, H.; Verhoeckx, K.

2015-01-01

The Ussing chamber system is named after the Danish zoologist Hans Ussing, who invented the device in the 1950s to measure the short-circuit current as an indicator of net ion transport taking place across frog skin (Ussing and Zerahn, Acta Physiol Scand 23:110-127, 1951). Ussing chambers are

Responses of slaughter pigs to transport and Lairage sounds.

NARCIS (Netherlands)

Geverink, N.A.; Buhneman, A.; Burgwal, van J.A.; Lambooij, E.; Blokhuis, H.J.; Wiegant, V.M.

1998-01-01

Geverink, N.A., A. Bühnemann, J.A. van de Burgwal, E. Lambooij, H.J. Blokhuis and V.M. Wiegant. Responses of slaughter pigs to transport and lairage sounds. Physiol Behav 63(4) 667–673, 1998. The behavioral and physiological responses of pigs to transport and subsequent exposure to slaughterhouse

Effect of ghrelin on glucose regulation in mice

NARCIS (Netherlands)

Chacko, Shaji K.; Haymond, Morey W.; Sun, Yuxiang; Marini, Juan C.; Sauer, Pieter J. J.; Ma, Xiaojun; Sunehag, Agneta L.

Chacko SK, Haymond MW, Sun Y, Marini JC, Sauer PJJ, Ma X, Sunehag AL. Effect of ghrelin on glucose regulation in mice. Am J Physiol Endocrinol Metab 302: E1055-E1062, 2012. First published February 14, 2011; doi:10.1152/ajpendo.00445.2011.-Improvement of glucose metabolism after bariatric surgery

NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease

NARCIS (Netherlands)

Sandford, Andrew J.; Malhotra, Deepti; Boezen, H. Marike; Siedlinski, Mateusz; Postma, Dirkje S.; Wong, Vivien; Akhabir, Loubna; He, Jian-Qing; Connett, John E.; Anthonisen, Nicholas R.; Pare, Peter D.; Biswal, Shyam

2012-01-01

Sandford AJ, Malhotra D, Boezen HM, Siedlinski M, Postma DS, Wong V, Akhabir L, He JQ, Connett JE, Anthonisen NR, Pare PD, Biswal S. NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. Physiol Genomics 44: 754-763, 2012. First published June 12, 2012;

Arterial pressure oscillations are not associated with muscle sympathetic nerve activity in individuals exposed to central hypovolaemia

Science.gov (United States)

2011-09-19

and Victor A. Convertino1 1US Army Institute of Surgical Research, Fort Sam Houston, TX 78234, USA 2Department of Health and Kinesiology , University of...during intense lower body negative pressure to presyncope in humans. J Physiol 587, 4987–4999. Cooke WH, Ryan KL & Convertino VA (2004). Lower body

Improving planting pattern for intercropping in the whole production ...

African Journals Online (AJOL)

DR. NJ TONUKARI

2012-04-26

Apr 26, 2012 ... vegetable for the people or to enrich biodiversity of rubber plantations in the area of hundred-miles rubber ..... Influence of rubber canopy on intercrop productivity. Trans. Malaysian Soc. Plant Physiol. 2: 75-79. Lin Weifu, Zhou Zhongyu, Huang Shoufeng (1999). A review and prospect of intercropping in ...

guinea grass

African Journals Online (AJOL)

SAM

2014-05-07

May 7, 2014 ... of metals in P. maximum tissues decreased in the order root > stem > foliage. ... effect clean up by phytoremediation is a function of the plant type and ... the spatial distribution of electrical conductivity (EC) may ... metals were measured weekly according to the method of Onianwa ..... Plant Cell Physiol.

Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate

NARCIS (Netherlands)

Mizutani, Makoto; Ito, Yasuhiko; Mizuno, Masashi; Nishimura, Hayato; Suzuki, Yasuhiro; Hattori, Ryohei; Matsukawa, Yoshihisa; Imai, Masaki; Oliver, Noelynn; Goldschmeding, Roel; Aten, Jan; Krediet, Raymond T.; Yuzawa, Yukio; Matsuo, Seiichi

2010-01-01

Mizutani M, Ito Y, Mizuno M, Nishimura H, Suzuki Y, Hattori R, Matsukawa Y, Imai M, Oliver N, Goldschmeding R, Aten J, Krediet RT, Yuzawa Y, Matsuo S. Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate. Am J Physiol

PROPRIEDADES TERMOFÍSICAS DE COMPÓSITO DE MATRIZ DE GESSO E FIBRA VEGETAL

Directory of Open Access Journals (Sweden)

George Santos Marinho

2013-03-01

Full Text Available Foi desenvolvido um compósito de matriz de gesso e reforço de fibra vegetal (Cocos nucifera destinado à fabricação de elementos construtivos (e. g., placas para forração de coberturas e painéis de vedação. Corpos de prova foram produzidos na forma de sanduíche de gesso / fibra / gesso. Duas espessuras diferentes da fatia de fibra foram consideradas: 8 mm e 10 mm. Um corpo de prova de gesso sem a fatia de fibra foi fabricado para servir como padrão de comparação. Utilizando-se um equipamento analisador térmico, foram realizados ensaios para determinação das seguintes propriedades termofísicas dos corpos de prova: condutividade térmica (k, capacidade térmica volumétrica (.CP e difusividade térmica (. A partir dos resultados foi possível evidenciar vantagens do compósito em relação ao padrão. O menor valor de k conferiu ao compósito uma maior capacidade de isolação, possibilitando redução da carga térmica no interior das edificações devido à radiação solar. Nsse aspecto, o compósito se mostra adequado ao uso como elemento de vedação em edificações situadas em localidades de baixas latitudes (e. g., região Nordeste do Brasil. Além das vantagens citadas, o compósito pode proporcionar mais leveza e economia de material, possibilitando a produção de elementos construtivos mais esbeltos.