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Sample records for input variables screen

  1. Statistical identification of effective input variables. [SCREEN

    Energy Technology Data Exchange (ETDEWEB)

    Vaurio, J.K.

    1982-09-01

    A statistical sensitivity analysis procedure has been developed for ranking the input data of large computer codes in the order of sensitivity-importance. The method is economical for large codes with many input variables, since it uses a relatively small number of computer runs. No prior judgemental elimination of input variables is needed. The sceening method is based on stagewise correlation and extensive regression analysis of output values calculated with selected input value combinations. The regression process deals with multivariate nonlinear functions, and statistical tests are also available for identifying input variables that contribute to threshold effects, i.e., discontinuities in the output variables. A computer code SCREEN has been developed for implementing the screening techniques. The efficiency has been demonstrated by several examples and applied to a fast reactor safety analysis code (Venus-II). However, the methods and the coding are general and not limited to such applications.

  2. Are Financial Variables Inputs in Delivered Production Functions? Are Financial Variables Inputs in Delivered Production Functions?

    Directory of Open Access Journals (Sweden)

    Miguel Kiguel

    1995-03-01

    Full Text Available Fischer's classic (1974 paper develops conditions under which it is appropriate to use money as an input in a 'delivered' production function. In this paper, we extend Fischer's model I (the Baumol-Tobin inventory approach by incorporating credit into the analysis. Our investigation of the extended model brings out a very restrictive but necessary implicit assumption employed by Fischer to treat money as an input. Namely. that there exists a binding constraint on the use of money! A similar result holds for our more general model. Fischer's classic (1974 paper develops conditions under which it is appropriate to use money as an input in a 'delivered' production function. In this paper, we extend Fischer's model I (the Baumol-Tobin inventory approach by incorporating credit into the analysis. Our investigation of the extended model brings out a very restrictive but necessary implicit assumption employed by Fischer to treat money as an input. Namely. that there exists a binding constraint on the use of money! A similar result holds for our more general model.

  3. Variable Input and the Acquisition of Plural Morphology

    Science.gov (United States)

    Miller, Karen L.; Schmitt, Cristina

    2012-01-01

    The present article examines the effect of variable input on the acquisition of plural morphology in two varieties of Spanish: Chilean Spanish, where the plural marker is sometimes omitted due to a phonological process of syllable final /s/ lenition, and Mexican Spanish (of Mexico City), with no such lenition process. The goal of the study is to…

  4. Sensitivity Analysis of the ALMANAC Model's Input Variables

    Institute of Scientific and Technical Information of China (English)

    XIE Yun; James R.Kiniry; Jimmy R.Williams; CHEN You-min; LIN Er-da

    2002-01-01

    Crop models often require extensive input data sets to realistically simulate crop growth. Development of such input data sets can be difficult for some model users. The objective of this study was to evaluate the importance of variables in input data sets for crop modeling. Based on published hybrid performance trials in eight Texas counties, we developed standard data sets of 10-year simulations of maize and sorghum for these eight counties with the ALMANAC (Agricultural Land Management Alternatives with Numerical Assessment Criteria) model. The simulation results were close to the measured county yields with relative error only 2.6%for maize, and - 0.6% for sorghum. We then analyzed the sensitivity of grain yield to solar radiation, rainfall, soil depth, soil plant available water, and runoff curve number, comparing simulated yields to those with the original, standard data sets. Runoff curve number changes had the greatest impact on simulated maize and sorghum yields for all the counties. The next most critical input was rainfall, and then solar radiation for both maize and sorghum, especially for the dryland condition. For irrigated sorghum, solar radiation was the second most critical input instead of rainfall. The degree of sensitivity of yield to all variables for maize was larger than for sorghum except for solar radiation. Many models use a USDA curve number approach to represent soil water redistribution, so it will be important to have accurate curve numbers, rainfall, and soil depth to realistically simulate yields.

  5. Kriging atomic properties with a variable number of inputs

    Science.gov (United States)

    Davie, Stuart J.; Di Pasquale, Nicodemo; Popelier, Paul L. A.

    2016-09-01

    A new force field called FFLUX uses the machine learning technique kriging to capture the link between the properties (energies and multipole moments) of topological atoms (i.e., output) and the coordinates of the surrounding atoms (i.e., input). Here we present a novel, general method of applying kriging to chemical systems that do not possess a fixed number of (geometrical) inputs. Unlike traditional kriging methods, which require an input system to be of fixed dimensionality, the method presented here can be readily applied to molecular simulation, where an interaction cutoff radius is commonly used and the number of atoms or molecules within the cutoff radius is not constant. The method described here is general and can be applied to any machine learning technique that normally operates under a fixed number of inputs. In particular, the method described here is also useful for interpolating methods other than kriging, which may suffer from difficulties stemming from identical sets of inputs corresponding to different outputs or input biasing. As a demonstration, the new method is used to predict 54 energetic and electrostatic properties of the central water molecule of a set of 5000, 4 Å radius water clusters, with a variable number of water molecules. The results are validated against equivalent models from a set of clusters composed of a fixed number of water molecules (set to ten, i.e., decamers) and against models created by using a naïve method of treating the variable number of inputs problem presented. Results show that the 4 Å water cluster models, utilising the method presented here, return similar or better kriging models than the decamer clusters for all properties considered and perform much better than the truncated models.

  6. Dynamics Behavior Research on Variable Linear Vibration Screen with Flexible Screen Face

    Directory of Open Access Journals (Sweden)

    Changlong Du

    2014-08-01

    Full Text Available In order to enable the variable linear vibration screen with ideal movement behavior of screen surface and efficient screening capacity, five-freedom dynamic model and stability equations of the variable linear vibration screen were established based on power balance method and Hamilton principle. The motion behaviour of screen face was investigated, and − 0.10 m ≤ xf ≤ − 0.04 m was confirmed as the best range of exciting position. With analysis of stability equations, the stable requirement of vibration screen was obtained: the direction angle of exciting force should be 0 ≤ θ ≤ 45°. Screening processes of variable linear vibration screen with flexible screen face, variable linear vibration screen with fixed screen face and linear vibration screen were investigated and compared by numerical simulation method, the results show that variable linear vibration screen with flexible screen face have such characteristics as higher intensity of projection and efficient screening. The correctness of theoretical research and simulation research were verified through experiment, and all of the work would provide some guidance for designing and studying variable linear vibration screen with flexible screen face.

  7. Simulator comparison of thumball, thumb switch, and touch screen input concepts for interaction with a large screen cockpit display format

    Science.gov (United States)

    Jones, Denise R.; Parrish, Russell V.

    1990-01-01

    A piloted simulation study was conducted comparing three different input methods for interfacing to a large screen, multiwindow, whole flight deck display for management of transport aircraft systems. The thumball concept utilized a miniature trackball embedded in a conventional side arm controller. The multifunction control throttle and stick (MCTAS) concept employed a thumb switch located in the throttle handle. The touch screen concept provided data entry through a capacitive touch screen installed on the display surface. The objective and subjective results obtained indicate that, with present implementations, the thumball concept was the most appropriate for interfacing with aircraft systems/subsystems presented on a large screen display. Not unexpectedly, the completion time differences between the three concepts varied with the task being performed, although the thumball implementation consistently outperformed the other two concepts. However, pilot suggestions for improved implementations of the MCTAS and touch screen concepts could reduce some of these differences.

  8. Dynamics Behavior Research on Variable Linear Vibration Screen with Flexible Screen Face

    OpenAIRE

    Changlong Du; Kuidong Gao; Jianping Li; Hao Jiang

    2014-01-01

    In order to enable the variable linear vibration screen with ideal movement behavior of screen surface and efficient screening capacity, five-freedom dynamic model and stability equations of the variable linear vibration screen were established based on power balance method and Hamilton principle. The motion behaviour of screen face was investigated, and − 0.10 m ≤ xf ≤ − 0.04 m was confirmed as the best range of exciting position. With analysis of stability equations, the stable requirement ...

  9. Speaker Input Variability Does Not Explain Why Larger Populations Have Simpler Languages.

    Directory of Open Access Journals (Sweden)

    Mark Atkinson

    Full Text Available A learner's linguistic input is more variable if it comes from a greater number of speakers. Higher speaker input variability has been shown to facilitate the acquisition of phonemic boundaries, since data drawn from multiple speakers provides more information about the distribution of phonemes in a speech community. It has also been proposed that speaker input variability may have a systematic influence on individual-level learning of morphology, which can in turn influence the group-level characteristics of a language. Languages spoken by larger groups of people have less complex morphology than those spoken in smaller communities. While a mechanism by which the number of speakers could have such an effect is yet to be convincingly identified, differences in speaker input variability, which is thought to be larger in larger groups, may provide an explanation. By hindering the acquisition, and hence faithful cross-generational transfer, of complex morphology, higher speaker input variability may result in structural simplification. We assess this claim in two experiments which investigate the effect of such variability on language learning, considering its influence on a learner's ability to segment a continuous speech stream and acquire a morphologically complex miniature language. We ultimately find no evidence to support the proposal that speaker input variability influences language learning and so cannot support the hypothesis that it explains how population size determines the structural properties of language.

  10. Researches on the Model of Telecommunication Service with Variable Input Tariff Rates

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The paper sets up and studies the model of the telecommunication queue servicing system with variable input tariff rates, which can relieve the crowding system traffic flows during the busy hour to enhance the utilizing rate of the telecom's resources.

  11. Structure Analysis of Typical Fuzzy Controllers with Unequally Spaced Fuzzy Sets for Input and Output Variables

    Institute of Scientific and Technical Information of China (English)

    FAN Xingzhe; ZHANG Naiyao; LINing

    2001-01-01

    In this paper, a kind of typical fuzzycontrollers is defined, which have two inputs (e and△c) and one output (△u); triangular, symmetric andfull-overlapped membership functions for input vari-ables; singleton and symmetric membership func-tions for output variable; linear fuzzy control rules;Sum-Product inference method, and weighted meanmethod for defuzzification. For this kind of typicalfuzzy controllers we have analyzed their analyticalstructure, limiting structure and local stability.

  12. LCA of emerging technologies: addressing high uncertainty on inputs' variability when performing global sensitivity analysis.

    Science.gov (United States)

    Lacirignola, Martino; Blanc, Philippe; Girard, Robin; Pérez-López, Paula; Blanc, Isabelle

    2017-02-01

    In the life cycle assessment (LCA) context, global sensitivity analysis (GSA) has been identified by several authors as a relevant practice to enhance the understanding of the model's structure and ensure reliability and credibility of the LCA results. GSA allows establishing a ranking among the input parameters, according to their influence on the variability of the output. Such feature is of high interest in particular when aiming at defining parameterized LCA models. When performing a GSA, the description of the variability of each input parameter may affect the results. This aspect is critical when studying new products or emerging technologies, where data regarding the model inputs are very uncertain and may cause misleading GSA outcomes, such as inappropriate input rankings. A systematic assessment of this sensitivity issue is now proposed. We develop a methodology to analyze the sensitivity of the GSA results (i.e. the stability of the ranking of the inputs) with respect to the description of such inputs of the model (i.e. the definition of their inherent variability). With this research, we aim at enriching the debate on the application of GSA to LCAs affected by high uncertainties. We illustrate its application with a case study, aiming at the elaboration of a simple model expressing the life cycle greenhouse gas emissions of enhanced geothermal systems (EGS) as a function of few key parameters. Our methodology allows identifying the key inputs of the LCA model, taking into account the uncertainty related to their description.

  13. Variable structure control for MRAC systems with perturbations in input and output channels

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A design scheme of variable structure model reference control systems using only input and output measurements is presented for the systems with unmodeled dynamics and disturbances in input and output channels. The modeled part of the systems has relative degree greater than one and unknown upper bound of degree. By introducing some auxiliary signals and normalized signals with memory functions and appropriate choice of controller parameters, the developed variable structure controller guarantees the global stability of the closed-loop system and the arbitrarily small tracking error.

  14. Graphical user interface for input output characterization of single variable and multivariable highly nonlinear systems

    Directory of Open Access Journals (Sweden)

    Shahrukh Adnan Khan M. D.

    2017-01-01

    Full Text Available This paper presents a Graphical User Interface (GUI software utility for the input/output characterization of single variable and multivariable nonlinear systems by obtaining the sinusoidal input describing function (SIDF of the plant. The software utility is developed on MATLAB R2011a environment. The developed GUI holds no restriction on the nonlinearity type, arrangement and system order; provided that output(s of the system is obtainable either though simulation or experiments. An insight to the GUI and its features are presented in this paper and example problems from both single variable and multivariable cases are demonstrated. The formulation of input/output behavior of the system is discussed and the nucleus of the MATLAB command underlying the user interface has been outlined. Some of the industries that would benefit from this software utility includes but not limited to aerospace, defense technology, robotics and automotive.

  15. Not All Children Agree: Acquisition of Agreement when the Input Is Variable

    Science.gov (United States)

    Miller, Karen

    2012-01-01

    In this paper we investigate the effect of variable input on the acquisition of grammar. More specifically, we examine the acquisition of the third person singular marker -s on the auxiliary "do" in comprehension and production in two groups of children who are exposed to similar varieties of English but that differ with respect to adult…

  16. Effects of uncertainty in major input variables on simulated functional soil behaviour

    NARCIS (Netherlands)

    Finke, P.A.; Wösten, J.H.M.; Jansen, M.J.W.

    1997-01-01

    Uncertainties in major input variables in water and solute models were quantified and their effects on simulated functional aspects of soil behaviour were studied using basic soil properties from an important soil map unit in the Netherlands. Two sources of uncertainty were studied: spatial

  17. Effects of uncertainty in major input variables on simulated functional soil behaviour

    NARCIS (Netherlands)

    Finke, P.A.; Wösten, J.H.M.; Jansen, M.J.W.

    1996-01-01

    Uncertainties in major input variables in water and solute models were quantified and their effects on simulated functional aspects of soil behaviour were studied using basic soil properties from an important soil map unit in the Netherlands. Two sources of uncertainty were studied: spatial

  18. Urban vs. Rural CLIL: An Analysis of Input-Related Variables, Motivation and Language Attainment

    Science.gov (United States)

    Alejo, Rafael; Piquer-Píriz, Ana

    2016-01-01

    The present article carries out an in-depth analysis of the differences in motivation, input-related variables and linguistic attainment of the students at two content and language integrated learning (CLIL) schools operating within the same institutional and educational context, the Spanish region of Extremadura, and differing only in terms of…

  19. Urban vs. Rural CLIL: An Analysis of Input-Related Variables, Motivation and Language Attainment

    Science.gov (United States)

    Alejo, Rafael; Piquer-Píriz, Ana

    2016-01-01

    The present article carries out an in-depth analysis of the differences in motivation, input-related variables and linguistic attainment of the students at two content and language integrated learning (CLIL) schools operating within the same institutional and educational context, the Spanish region of Extremadura, and differing only in terms of…

  20. Analysis of input variables of an artificial neural network using bivariate correlation and canonical correlation

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Valter Magalhaes; Pereira, Iraci Martinez, E-mail: valter.costa@usp.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The monitoring of variables and diagnosis of sensor fault in nuclear power plants or processes industries is very important because a previous diagnosis allows the correction of the fault and, like this, to prevent the production stopped, improving operator's security and it's not provoking economics losses. The objective of this work is to build a set, using bivariate correlation and canonical correlation, which will be the set of input variables of an artificial neural network to monitor the greater number of variables. This methodology was applied to the IEA-R1 Research Reactor at IPEN. Initially, for the input set of neural network we selected the variables: nuclear power, primary circuit flow rate, control/safety rod position and difference in pressure in the core of the reactor, because almost whole of monitoring variables have relation with the variables early described or its effect can be result of the interaction of two or more. The nuclear power is related to the increasing and decreasing of temperatures as well as the amount radiation due fission of the uranium; the rods are controls of power and influence in the amount of radiation and increasing and decreasing of temperatures; the primary circuit flow rate has the function of energy transport by removing the nucleus heat. An artificial neural network was trained and the results were satisfactory since the IEA-R1 Data Acquisition System reactor monitors 64 variables and, with a set of 9 input variables resulting from the correlation analysis, it was possible to monitor 51 variables. (author)

  1. Bootstrap rank-ordered conditional mutual information (broCMI): A nonlinear input variable selection method for water resources modeling

    Science.gov (United States)

    Quilty, John; Adamowski, Jan; Khalil, Bahaa; Rathinasamy, Maheswaran

    2016-03-01

    The input variable selection problem has recently garnered much interest in the time series modeling community, especially within water resources applications, demonstrating that information theoretic (nonlinear)-based input variable selection algorithms such as partial mutual information (PMI) selection (PMIS) provide an improved representation of the modeled process when compared to linear alternatives such as partial correlation input selection (PCIS). PMIS is a popular algorithm for water resources modeling problems considering nonlinear input variable selection; however, this method requires the specification of two nonlinear regression models, each with parametric settings that greatly influence the selected input variables. Other attempts to develop input variable selection methods using conditional mutual information (CMI) (an analog to PMI) have been formulated under different parametric pretenses such as k nearest-neighbor (KNN) statistics or kernel density estimates (KDE). In this paper, we introduce a new input variable selection method based on CMI that uses a nonparametric multivariate continuous probability estimator based on Edgeworth approximations (EA). We improve the EA method by considering the uncertainty in the input variable selection procedure by introducing a bootstrap resampling procedure that uses rank statistics to order the selected input sets; we name our proposed method bootstrap rank-ordered CMI (broCMI). We demonstrate the superior performance of broCMI when compared to CMI-based alternatives (EA, KDE, and KNN), PMIS, and PCIS input variable selection algorithms on a set of seven synthetic test problems and a real-world urban water demand (UWD) forecasting experiment in Ottawa, Canada.

  2. Identification of multiple inputs single output errors-in-variables system using cumulant

    Institute of Scientific and Technical Information of China (English)

    Haihui Long; Jiankang Zhao

    2014-01-01

    A higher-order cumulant-based weighted least square (HOCWLS) and a higher-order cumulant-based iterative least square (HOCILS) are derived for multiple inputs single output (MISO) errors-in-variables (EIV) systems from noisy input/output data. Whether the noises of the input/output of the system are white or colored, the proposed algorithms can be insensitive to these noises and yield unbiased estimates. To realize adaptive pa-rameter estimates, a higher-order cumulant-based recursive least square (HOCRLS) method is also studied. Convergence analy-sis of the HOCRLS is conducted by using the stochastic process theory and the stochastic martingale theory. It indicates that the parameter estimation error of HOCRLS consistently converges to zero under a generalized persistent excitation condition. The use-fulness of the proposed algorithms is assessed through numerical simulations.

  3. Input variable selection for data-driven models of Coriolis flowmeters for two-phase flow measurement

    Science.gov (United States)

    Wang, Lijuan; Yan, Yong; Wang, Xue; Wang, Tao

    2017-03-01

    Input variable selection is an essential step in the development of data-driven models for environmental, biological and industrial applications. Through input variable selection to eliminate the irrelevant or redundant variables, a suitable subset of variables is identified as the input of a model. Meanwhile, through input variable selection the complexity of the model structure is simplified and the computational efficiency is improved. This paper describes the procedures of the input variable selection for the data-driven models for the measurement of liquid mass flowrate and gas volume fraction under two-phase flow conditions using Coriolis flowmeters. Three advanced input variable selection methods, including partial mutual information (PMI), genetic algorithm-artificial neural network (GA-ANN) and tree-based iterative input selection (IIS) are applied in this study. Typical data-driven models incorporating support vector machine (SVM) are established individually based on the input candidates resulting from the selection methods. The validity of the selection outcomes is assessed through an output performance comparison of the SVM based data-driven models and sensitivity analysis. The validation and analysis results suggest that the input variables selected from the PMI algorithm provide more effective information for the models to measure liquid mass flowrate while the IIS algorithm provides a fewer but more effective variables for the models to predict gas volume fraction.

  4. Rank correlation plots for use with correlated input variables in simulation studies

    Energy Technology Data Exchange (ETDEWEB)

    Iman, R.L.; Davenport, J.M.

    1980-11-01

    A method for inducing a desired rank correlation matrix on multivariate input vectors for simulation studies has recently been developed by Iman and Conover (SAND 80-0157). The primary intention of this procedure is to produce correlated input variables for use with computer models. Since this procedure is distribution free and allows the exact marginal distributions to remain intact, it can be used with any marginal distributions for which it is reasonable to think in terms of correlation. A series of rank correlation plots based on this procedure when the marginal distributions are normal, lognormal, uniform, and loguniform is presented. These plots provide a convenient tool for both aiding the modeler in determining the degree of dependence among variables (rather than guessing) and communicating with the modeler the effect of different correlation assumptions. 12 figures, 10 tables.

  5. Method and apparatus for smart battery charging including a plurality of controllers each monitoring input variables

    Science.gov (United States)

    Hammerstrom, Donald J.

    2013-10-15

    A method for managing the charging and discharging of batteries wherein at least one battery is connected to a battery charger, the battery charger is connected to a power supply. A plurality of controllers in communication with one and another are provided, each of the controllers monitoring a subset of input variables. A set of charging constraints may then generated for each controller as a function of the subset of input variables. A set of objectives for each controller may also be generated. A preferred charge rate for each controller is generated as a function of either the set of objectives, the charging constraints, or both, using an algorithm that accounts for each of the preferred charge rates for each of the controllers and/or that does not violate any of the charging constraints. A current flow between the battery and the battery charger is then provided at the actual charge rate.

  6. Wide Input Range Power Converters Using a Variable Turns Ratio Transformer

    DEFF Research Database (Denmark)

    Ouyang, Ziwei; Andersen, Michael A. E.

    2016-01-01

    A new integrated transformer with variable turns ratio is proposed to enable dc-dc converters operating over a wide input voltage range. The integrated transformer employs a new geometry of magnetic core with “four legs”, two primary windings with orthogonal arrangement, and “8” shape connection...... of diagonal secondary windings, in order to make the transformer turns ratio adjustable by controlling the phase between the two current excitations subjected to the two primary windings. Full-bridge boost dc-dc converter is employed with the proposed transformer to demonstrate the feasibility of the variable...

  7. Risk assessment of finishing beef cattle in feedlot: slaughter weights and correlation amongst input variables

    Directory of Open Access Journals (Sweden)

    Paulo Santana Pacheco

    2014-02-01

    Full Text Available The objective of this study was to evaluate the risk associated with finishing crossbred Charolais × Nellore steers in feedlot at different slaughter weights (425, 467 or 510 kg, considering or disregarding the correlation amongst random input variables. Data were collected from 2004 to 2010 and used in the simulation of the financial indicator Net Present Value (NPV. Animals slaughtered with 425, 467 or 510 kg were fed diets containing a roughage:concentrate ratio of 60:40 for 30, 65 and 94 days, respectively. In the simulation of NPV, a Latin Hypercube type of sampling was used, running 2000 interactions. An analysis of stochastic dominance of first and second orders was carried out as well as the Kolmogorov-Smirnov asymptotic test (to check for differences between pairs of curves of cumulative distributions, followed by sensitivity analysis using stepwise multivariate regression. Simulations of NPV considering the correlation amongst the input variables produced more consistent estimates of this financial indicator than simulations that disregarded it. The risk analysis showed that 467 kg slaughter weight presented the lowest risk for finishing cattle in feedlots when compared with 425 and 510 kg. The most important variables influencing the NVP are the prices of feeder and finished steers, initial and final weights, concentrate and roughage costs, and minimum rate of attractiveness; therefore, farmers should pay particular attention to these variables when making the decision of whether or not to use feedlot to finish beef cattle.

  8. Variable input observer for structural health monitoring of high-rate systems

    Science.gov (United States)

    Hong, Jonathan; Laflamme, Simon; Cao, Liang; Dodson, Jacob

    2017-02-01

    The development of high-rate structural health monitoring methods is intended to provide damage detection on timescales of 10 µs -10ms where speed of detection is critical to maintain structural integrity. Here, a novel Variable Input Observer (VIO) coupled with an adaptive observer is proposed as a potential solution for complex high-rate problems. The VIO is designed to adapt its input space based on real-time identification of the system's essential dynamics. By selecting appropriate time-delayed coordinates defined by both a time delay and an embedding dimension, the proper input space is chosen which allows more accurate estimations of the current state and a reduction of the convergence rate. The optimal time-delay is estimated based on mutual information, and the embedding dimension is based on false nearest neighbors. A simulation of the VIO is conducted on a two degree-of-freedom system with simulated damage. Results are compared with an adaptive Luenberger observer, a fixed time-delay observer, and a Kalman Filter. Under its preliminary design, the VIO converges significantly faster than the Luenberger and fixed observer. It performed similarly to the Kalman Filter in terms of convergence, but with greater accuracy.

  9. Optimality of Graphlet Screening in High Dimensional Variable Selection

    CERN Document Server

    Jin, Jiashun; Zhang, Qi

    2012-01-01

    Consider a linear regression model where the design matrix X has n rows and p columns. We assume (a) p is much large than n, (b) the coefficient vector beta is sparse in the sense that only a small fraction of its coordinates is nonzero, and (c) the Gram matrix G = X'X is sparse in the sense that each row has relatively few large coordinates (diagonals of G are normalized to 1). The sparsity in G naturally induces the sparsity of the so-called graph of strong dependence (GOSD). We find an interesting interplay between the signal sparsity and the graph sparsity, which ensures that in a broad context, the set of true signals decompose into many different small-size components of GOSD, where different components are disconnected. We propose Graphlet Screening (GS) as a new approach to variable selection, which is a two-stage Screen and Clean method. The key methodological innovation of GS is to use GOSD to guide both the screening and cleaning. Compared to m-variate brute-forth screening that has a computational...

  10. Simulation model structure numerically robust to changes in magnitude and combination of input and output variables

    DEFF Research Database (Denmark)

    Rasmussen, Bjarne D.; Jakobsen, Arne

    1999-01-01

    instabilities prevent the practical use of such a system model for more than one input/output combination and for other magnitudes of refrigerating capacities.A higher numerical robustness of system models can be achieved by making a model for the refrigeration cycle the core of the system model and by using...... variables with narrow definition intervals for the exchange of information between the cycle model and the component models.The advantages of the cycle-oriented method are illustrated by an example showing the refrigeration cycle similarities between two very different refrigeration systems.......Mathematical models of refrigeration systems are often based on a coupling of component models forming a “closed loop” type of system model. In these models the coupling structure of the component models represents the actual flow path of refrigerant in the system. Very often numerical...

  11. Attitude Control Considering Variable Input Saturation Limit for a Spacecraft Equipped with Flywheels

    Institute of Scientific and Technical Information of China (English)

    TIAN Lin; XU Shijie

    2012-01-01

    A new attitude controller is proposed for spacecraft whose actuator has variable input saturation limit.There are three identical flywheels orthogonally mounted on board.Each rotor is driven by a brushless DC motor (BLDCM).Models of spacecraft attitude dynamics and flywheel rotor driving motor electromechanics are discussed in detail.The controller design is similar to saturation limit linear assignment.An auxiliary parameter and a boundary coefficient are imported into the controller to guarantee system stability and improve control performance.A time-varying and state-dependent flywheel output torque saturation limit model is established.Stability of the closed-loop control system and asymptotic convergence of system states are proved via Lyapunov methods and LaSalle invarianee principle.Boundedness of the auxiliary parameter ensures that the control objective can be achieved,while the boundary parameter's value makes a balance between system control performance and flywheel utilization efficiency.Compared with existing controllers,the newly developed controller with variable torque saturation limit can bring smoother control and faster system response.Numerical simulations validate the effectiveness of the controller.

  12. A Study on the Fuzzy-Logic-Based Solar Power MPPT Algorithms Using Different Fuzzy Input Variables

    Directory of Open Access Journals (Sweden)

    Jaw-Kuen Shiau

    2015-04-01

    Full Text Available Maximum power point tracking (MPPT is one of the key functions of the solar power management system in solar energy deployment. This paper investigates the design of fuzzy-logic-based solar power MPPT algorithms using different fuzzy input variables. Six fuzzy MPPT algorithms, based on different input variables, were considered in this study, namely (i slope (of solar power-versus-solar voltage and changes of the slope; (ii slope and variation of the power; (iii variation of power and variation of voltage; (iv variation of power and variation of current; (v sum of conductance and increment of the conductance; and (vi sum of angles of arctangent of the conductance and arctangent of increment of the conductance. Algorithms (i–(iv have two input variables each while algorithms (v and (vi use a single input variable. The fuzzy logic MPPT function is deployed using a buck-boost power converter. This paper presents the details of the determinations, considerations of the fuzzy rules, as well as advantages and disadvantages of each MPPT algorithm based upon photovoltaic (PV cell properties. The range of the input variable of Algorithm (vi is finite and the maximum power point condition is well defined in steady condition and, therefore, it can be used for multipurpose controller design. Computer simulations are conducted to verify the design.

  13. Effect of variable heat input on the heat transfer characteristics in an Organic Rankine Cycle system

    Directory of Open Access Journals (Sweden)

    Aboaltabooq Mahdi Hatf Kadhum

    2016-01-01

    Full Text Available This paper analyzes the heat transfer characteristics of an ORC evaporator applied on a diesel engine using measured data from experimental work such as flue gas mass flow rate and flue gas temperature. A mathematical model was developed with regard to the preheater, boiler and the superheater zones of a counter flow evaporator. Each of these zones has been subdivided into a number of cells. The hot source of the ORC cycle was modeled. The study involves the variable heat input's dependence on the ORC system's heat transfer characteristics, with especial emphasis on the evaporator. The results show that the refrigerant's heat transfer coefficient has a higher value for a 100% load from the diesel engine, and decreases with the load decrease. Also, on the exhaust gas side, the heat transfer coefficient decreases with the decrease of the load. The refrigerant's heat transfer coefficient increased normally with the evaporator's tube length in the preheater zone, and then increases rapidly in the boiler zone, followed by a decrease in the superheater zone. The exhaust gases’ heat transfer coefficient increased with the evaporator’ tube length in all zones. The results were compared with result by other authors and were found to be in agreement.

  14. Effect of variable heat input on the heat transfer characteristics in an Organic Rankine Cycle system

    Directory of Open Access Journals (Sweden)

    Aboaltabooq Mahdi Hatf Kadhum

    2016-01-01

    Full Text Available This paper analyzes the heat transfer characteristics of an ORC evaporator applied on a diesel engine using measured data from experimental work such as flue gas mass flow rate and flue gas temperature. A mathematical model was developed with regard to the preheater, boiler and the superheater zones of a counter flow evaporator. Each of these zones has been subdivided into a number of cells. The hot source of the ORC cycle was modeled. The study involves the variable heat input's dependence on the ORC system's heat transfer characteristics, with especial emphasis on the evaporator. The results show that the refrigerant's heat transfer coefficient has a higher value for a 100% load from the diesel engine, and decreases with the load decrease. Also, on the exhaust gas side, the heat transfer coefficient decreases with the decrease of the load. The refrigerant's heat transfer coefficient increased normally with the evaporator's tube length in the preheater zone, and then increases rapidly in the boiler zone, followed by a decrease in the superheater zone. The exhaust gases’ heat transfer coefficient increased with the evaporator’ tube length in all zones. The results were compared with result by other authors and were found to be in agreement.

  15. Input variable selection for water resources systems using a modified minimum redundancy maximum relevance (mMRMR) algorithm

    Science.gov (United States)

    Hejazi, Mohamad I.; Cai, Ximing

    2009-04-01

    Input variable selection (IVS) is a necessary step in modeling water resources systems. Neglecting this step may lead to unnecessary model complexity and reduced model accuracy. In this paper, we apply the minimum redundancy maximum relevance (MRMR) algorithm to identifying the most relevant set of inputs in modeling a water resources system. We further introduce two modified versions of the MRMR algorithm ( α-MRMR and β-MRMR), where α and β are correction factors that are found to increase and decrease as a power-law function, respectively, with the progress of the input selection algorithms and the increase of the number of selected input variables. We apply the proposed algorithms to 22 reservoirs in California to predict daily releases based on a set from a 121 potential input variables. Results indicate that the two proposed algorithms are good measures of model inputs as reflected in enhanced model performance. The α-MRMR and β-MRMR values exhibit strong negative correlation to model performance as depicted in lower root-mean-square-error (RMSE) values.

  16. Behavioral and Electrophysiological Evidence for Early and Automatic Detection of Phonological Equivalence in Variable Speech Inputs

    Science.gov (United States)

    Kharlamov, Viktor; Campbell, Kenneth; Kazanina, Nina

    2011-01-01

    Speech sounds are not always perceived in accordance with their acoustic-phonetic content. For example, an early and automatic process of perceptual repair, which ensures conformity of speech inputs to the listener's native language phonology, applies to individual input segments that do not exist in the native inventory or to sound sequences that…

  17. Ergonomic problems regarding the interactive touch input via screens in onboard and ground-based flight control

    Science.gov (United States)

    Holzhausen, K. P.; Gaertner, K. P.

    1985-01-01

    A significant problem concerning the integration of display and switching functions is related to the fact that numerous informative data which have to be processed by man must be read from only a few display devices. A satisfactory ergonomic design of integrated display devices and keyboards is in many cases difficult, because not all functions which can be displayed and selected are simultaneously available. A technical solution which provides an integration of display and functional elements on the basis of the highest flexibility is obtained by using a cathode ray tube with a touch-sensitive screen. The employment of an integrated data input/output system is demonstrated for the cases of onboard and ground-based flight control. Ergonomic studies conducted to investigate the suitability of an employment of touch-sensitive screens are also discussed.

  18. Assessment of input uncertainty by seasonally categorized latent variables using SWAT

    Science.gov (United States)

    Watershed processes have been explored with sophisticated simulation models for the past few decades. It has been stated that uncertainty attributed to alternative sources such as model parameters, forcing inputs, and measured data should be incorporated during the simulation process. Among varyin...

  19. A GENERAL APPROACH BASED ON AUTOCORRELATION TO DETERMINE INPUT VARIABLES OF NEURAL NETWORKS FOR TIME SERIES FORECASTING

    Institute of Scientific and Technical Information of China (English)

    HUANG Wei; NAKAMORI Yoshiteru; WANG Shouyang

    2004-01-01

    Input selection is probably one of the most critical decision issues in neural network designing, because it has a great impact on forecasting performance. Among the many applications of artificial neural networks to finance, time series forecasting is perhaps one of the most challenging issues. Considering the features of neural networks, we propose a general approach called Autocorrelation Criterion (AC) to determine the inputs variables for a neural network. The purpose is to seek optimal lag periods, which are more predictive and less correlated. AC is a data-driven approach in that there is no prior assumption about the models for time series under study. So it has extensive applications and avoids a lengthy experimentation and tinkering in input selection. We apply the approach to the determination of input variables for foreign exchange rate forecasting and conduct comparisons between AC and information-based in-sample model selection criterion. The experiment results show that AC outperforms information-based in-sample model selection criterion.

  20. Neural Network Based Scheduling for Variable-Length Packets in Gigabit Router with Crossbar Switch Fabric and Input Queuing

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A high-speed and effective packet scheduling method is crucial to the performance of Gigabit routers. The paper studies the variable-length packet scheduling problem in Gigabit router with crossbar switch fabric and input queuing, and a scheduling method based on neural network is proposed. For the proposed method, a scheduling system structure fit for the variable-length packet case is presented first, then some rules for scheduling are given, At last, an optimal scheduling method using Hopfield neural network is proposed based on the rules. Furthermore, the paper discusses that the proposed method can be realized by hardware circuit. The simulation result shows the effectiveness of the proposed method.

  1. A DNA-based system for selecting and displaying the combined result of two input variables

    DEFF Research Database (Denmark)

    Liu, Huajie; Wang, Jianbang; Song, S

    2015-01-01

    Oligonucleotide-based technologies for biosensing or bio-regulation produce huge amounts of rich high-dimensional information. There is a consequent need for flexible means to combine diverse pieces of such information to form useful derivative outputs, and to display those immediately. Here we...... demonstrate this capability in a DNA-based system that takes two input numbers, represented in DNA strands, and returns the result of their multiplication, writing this as a number in a display. Unlike a conventional calculator, this system operates by selecting the result from a library of solutions rather...

  2. Improving land cover classification using input variables derived from a geographically weighted principal components analysis

    Science.gov (United States)

    Comber, Alexis J.; Harris, Paul; Tsutsumida, Narumasa

    2016-09-01

    This study demonstrates the use of a geographically weighted principal components analysis (GWPCA) of remote sensing imagery to improve land cover classification accuracy. A principal components analysis (PCA) is commonly applied in remote sensing but generates global, spatially-invariant results. GWPCA is a local adaptation of PCA that locally transforms the image data, and in doing so, can describe spatial change in the structure of the multi-band imagery, thus directly reflecting that many landscape processes are spatially heterogenic. In this research the GWPCA localised loadings of MODIS data are used as textural inputs, along with GWPCA localised ranked scores and the image bands themselves to three supervised classification algorithms. Using a reference data set for land cover to the west of Jakarta, Indonesia the classification procedure was assessed via training and validation data splits of 80/20, repeated 100 times. For each classification algorithm, the inclusion of the GWPCA loadings data was found to significantly improve classification accuracy. Further, but more moderate improvements in accuracy were found by additionally including GWPCA ranked scores as textural inputs, data that provide information on spatial anomalies in the imagery. The critical importance of considering both spatial structure and spatial anomalies of the imagery in the classification is discussed, together with the transferability of the new method to other studies. Research topics for method refinement are also suggested.

  3. Variable Structure Controller with Time-Varying Switching Surface under the Bound of Input using Evolution Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Min Jung; Choi, Young Kiu [Pusan National University (Korea); Kim, Hyun Sik [Agency for Defense Development (Korea); Jeon, Seong Jeub [Pukyong National University (Korea)

    1999-04-01

    Variable structure control law is well known to be a robust control algorithm and evolution strategy is used as an effective search algorithm in optimization problems. In this paper, we propose a variable structure controller with time-varying switching surface. We calculate the maximum value of switching surface gradient under the bound of input. To enhance the robustness, we choose a time-varying switching surface gradient that is of the 3 rd order polynomial form. Evolution strategy is used to optimize the parameters of the switching surface gradient. Finally, the proposed method is applied to position tracking control for BLDC motor. Experimental results show that the proposed method is more useful than the conventional variable structure control. (author). 8 refs., 16 figs., 1 tab.

  4. Experimental demonstration of continuous variable cloning with phase-conjugate inputs

    DEFF Research Database (Denmark)

    Sabuncu, Metin; Andersen, Ulrik Lund; Leuchs, G.

    2007-01-01

    We report the first experimental demonstration of continuous variable cloning of phase-conjugate coherent states as proposed by Cerf and Iblisdir [Phys. Rev. Lett. 87, 247903 (2001)]. In contrast to this proposal, the cloning transformation is accomplished using only linear optical components......, homodyne detection, and feedforward. As a result of combining phase conjugation with a joint measurement strategy, superior cloning is demonstrated with cloning fidelities reaching 89%....

  5. An Efficient Variable Screening Method for Effective Surrogate Models for Reliability-Based Design Optimization

    Science.gov (United States)

    2014-04-01

    reliability-based design optimization ( RBDO ) process, surrogate models are frequently used to reduce the number of simulations because analysis of a...the RBDO problem and thus mitigate the curse of dimensionality. Therefore, it is desirable to develop an efficient and effective variable...screening method for reduction of the dimension of the RBDO problem. In this paper, requirements of the variable screening method for deterministic design

  6. Comparison of friction stir welding heat transfer analysis methods and parametric study on unspecified input variables

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sung Wook; Jang, Beom Seon [Seoul National University, Seoul (Korea, Republic of)

    2014-10-15

    A three-dimensional numerical model was constructed to analyze the heat transfer of friction stir welding using Fluent and ANSYS multi-physics. The analysis result was used to calculate welding deformation and residual stress. Before the numerical simulation, several simplifying assumptions were applied to the model. Three different methods of heat transfer analysis were employed, and several assumptions were applied to each heat source model. In this work, several parametric studies were performed for certain unspecified variables. The calculated temperature data were compared with experimental data from relevant studies. Additionally, the advantages and disadvantages of the three heat transfer analysis methods were compared.

  7. Paleodust variability since the Last Glacial Maximum and implications for iron inputs to the ocean

    Science.gov (United States)

    Albani, S.; Mahowald, N. M.; Murphy, L. N.; Raiswell, R.; Moore, J. K.; Anderson, R. F.; McGee, D.; Bradtmiller, L. I.; Delmonte, B.; Hesse, P. P.; Mayewski, P. A.

    2016-04-01

    Changing climate conditions affect dust emissions and the global dust cycle, which in turn affects climate and biogeochemistry. In this study we use observationally constrained model reconstructions of the global dust cycle since the Last Glacial Maximum, combined with different simplified assumptions of atmospheric and sea ice processing of dust-borne iron, to provide estimates of soluble iron deposition to the oceans. For different climate conditions, we discuss uncertainties in model-based estimates of atmospheric processing and dust deposition to key oceanic regions, highlighting the large degree of uncertainty of this important variable for ocean biogeochemistry and the global carbon cycle. We also show the role of sea ice acting as a time buffer and processing agent, which results in a delayed and pulse-like soluble iron release into the ocean during the melting season, with monthly peaks up to ~17 Gg/month released into the Southern Oceans during the Last Glacial Maximum (LGM).

  8. Optimization modeling of U.S. renewable electricity deployment using local input variables

    Science.gov (United States)

    Bernstein, Adam

    For the past five years, state Renewable Portfolio Standard (RPS) laws have been a primary driver of renewable electricity (RE) deployments in the United States. However, four key trends currently developing: (i) lower natural gas prices, (ii) slower growth in electricity demand, (iii) challenges of system balancing intermittent RE within the U.S. transmission regions, and (iv) fewer economical sites for RE development, may limit the efficacy of RPS laws over the remainder of the current RPS statutes' lifetime. An outsized proportion of U.S. RE build occurs in a small number of favorable locations, increasing the effects of these variables on marginal RE capacity additions. A state-by-state analysis is necessary to study the U.S. electric sector and to generate technology specific generation forecasts. We used LP optimization modeling similar to the National Renewable Energy Laboratory (NREL) Renewable Energy Development System (ReEDS) to forecast RE deployment across the 8 U.S. states with the largest electricity load, and found state-level RE projections to Year 2031 significantly lower than thoseimplied in the Energy Information Administration (EIA) 2013 Annual Energy Outlook forecast. Additionally, the majority of states do not achieve their RPS targets in our forecast. Combined with the tendency of prior research and RE forecasts to focus on larger national and global scale models, we posit that further bottom-up state and local analysis is needed for more accurate policy assessment, forecasting, and ongoing revision of variables as parameter values evolve through time. Current optimization software eliminates much of the need for algorithm coding and programming, allowing for rapid model construction and updating across many customized state and local RE parameters. Further, our results can be tested against the empirical outcomes that will be observed over the coming years, and the forecast deviation from the actuals can be attributed to discrete parameter

  9. Quasi-supervised scoring of human sleep in polysomnograms using augmented input variables.

    Science.gov (United States)

    Yaghouby, Farid; Sunderam, Sridhar

    2015-04-01

    The limitations of manual sleep scoring make computerized methods highly desirable. Scoring errors can arise from human rater uncertainty or inter-rater variability. Sleep scoring algorithms either come as supervised classifiers that need scored samples of each state to be trained, or as unsupervised classifiers that use heuristics or structural clues in unscored data to define states. We propose a quasi-supervised classifier that models observations in an unsupervised manner but mimics a human rater wherever training scores are available. EEG, EMG, and EOG features were extracted in 30s epochs from human-scored polysomnograms recorded from 42 healthy human subjects (18-79 years) and archived in an anonymized, publicly accessible database. Hypnograms were modified so that: 1. Some states are scored but not others; 2. Samples of all states are scored but not for transitional epochs; and 3. Two raters with 67% agreement are simulated. A framework for quasi-supervised classification was devised in which unsupervised statistical models-specifically Gaussian mixtures and hidden Markov models--are estimated from unlabeled training data, but the training samples are augmented with variables whose values depend on available scores. Classifiers were fitted to signal features incorporating partial scores, and used to predict scores for complete recordings. Performance was assessed using Cohen's Κ statistic. The quasi-supervised classifier performed significantly better than an unsupervised model and sometimes as well as a completely supervised model despite receiving only partial scores. The quasi-supervised algorithm addresses the need for classifiers that mimic scoring patterns of human raters while compensating for their limitations.

  10. Sediment records of highly variable mercury inputs to mountain lakes in Patagonia during the past millennium

    Science.gov (United States)

    Ribeiro Guevara, S.; Meili, M.; Rizzo, A.; Daga, R.; Arribére, M.

    2010-04-01

    High Hg levels in the pristine lacustrine ecosystems of the Nahuel Huapi National Park, a protected zone situated in the Andes of Northern Patagonia, Argentina, have initiated further investigations on Hg cycling and source identification. Here we report Hg records in sedimentary sequences to identify atmospheric sources during the past millennium. In addition to global transport and deposition, a potential atmospheric Hg source to be considered is the local emissions associated with volcanic activity, because the Park is situated in the Southern Volcanic Zone. Two sediment cores were extracted from Lake Tonček, a small, high-altitude system reflecting mainly direct inputs associated with atmospheric contributions, and Lake Moreno Oeste, a much larger and deeper lake having an extended watershed covered mostly by native forest. The sedimentary sequences were dated based on both 210Pb and 137Cs profiles. In addition, tephra layers were identified and geochemically characterized for chronological application and to investigate any association of volcanic eruptions with Hg records. Hg concentrations in sediments were measured along with 32 other elements, as well as organic matter, subfossil chironomids, and biogenic silica. Observed background Hg concentrations, determined from the sequence domains with lower values, ranged from 50 to 100 ng g-1 dry weight (DW), whereas the surficial layers reached 200 to 500 ng g-1 DW. In addition to this traditional pattern, however, two deep domains in both sequences showed dramatically increased Hg levels reaching 400 to 650 ng g-1 DW; the upper dated to the 18th to 19th centuries, and the lower around the 13th century. These concentrations are not only elevated in the present profiles but also many-fold above the background values determined in other fresh water sediments, as were also the Hg fluxes, reaching 120 to 150 μg m-2 y-1 in Lake Tonček . No correlation was observed between Hg concentrations and the contents of

  11. Variable temperature performance of a fully screen printed transistor switch

    Science.gov (United States)

    Zambou, Serges; Magunje, Batsirai; Rhyme, Setshedi; Walton, Stanley D.; Idowu, M. Florence; Unuigbe, David; Britton, David T.; Härting, Margit

    2016-12-01

    This article reports on the variable temperature performance of a flexible printed transistor which works as a current driven switch. In this work, electronic ink is formulated from nanostructured silicon produced by milling polycrystalline silicon. The study of the silicon active layer shows that its conductivity is based on thermal activation of carriers, and could be used as active layers in active devices. We further report on the transistors switching operation and their electrical performance under variable temperature. The reliability of the transistors at constant current bias was also investigated. Analysis of the electrical transfer characteristics from 340 to 10 K showed that the printed devices' current ON/OFF ratio increases as temperature decreases making it a better switch at lower temperatures. A constant current bias on a terminal for up to six hours shows extraordinary stability in electrical performance of the device.

  12. Effects of reconstruction filter and input parameter variability on object detectability in CT imaging

    Science.gov (United States)

    Boedeker, Kirsten L.

    The purpose of this work is to investigate and quantify the effects of technical parameter variability and reconstruction algorithm on image quality and object detectability. To accomplish this, metrics of both noise and signal to noise ratio (SNR) are explored and then applied in object detection tasks using a computer aided diagnosis (CAD) system. The noise power spectrum (NPS) is investigated as a noise metric in that it describes both the magnitude of noise and the spatial characteristics of noise that are introduced by the reconstruction algorithm. The NPS was found to be much more robust than the conventional standard deviation metric. The noise equivalent quanta (NEQ) is also studied as a tool for comparing effects of acquisition parameters (esp. mAs) on noise and, as NEQ is not influenced by reconstruction filter or other post-processing, its utility for comparison across different techniques and manufacturers is demonstrated. The Ideal Bayesian Observer (IBO) and Non-Prewhitening Matched Filter (NPWMF) are investigated as SNR metrics under a variety of acquisition and reconstruction conditions. The signal and noise processes of image formation were studied individually, which allowed for analysis of their separate effects on the overall SNR. The SNR metrics were found to characterize the influence of reconstruction filter and technical parameter variability with high sensitivity. To correlate the above SNR metrics with detection, signal images were combined with noise images and passed to a CAD system. A simulated lung nodule detection task was performed on a series of objects of increasing contrast. The average minimum contrast detected and corresponding IBO and NPWMF SNR values were recorded over 100 trials for each reconstruction filter and technical parameter condition studied. Among the trends discovered, it was found that detectability scales with SNR as mAs is varied. Furthermore, the CAD system appears to under-perform when sharp algorithms are

  13. Predicting coral species richness: the effect of input variables, diversity and scale.

    Science.gov (United States)

    Richards, Zoe T; Hobbs, Jean-Paul A

    2014-01-01

    Coral reefs are facing a biodiversity crisis due to increasing human impacts, consequently, one third of reef-building corals have an elevated risk of extinction. Logistic challenges prevent broad-scale species-level monitoring of hard corals; hence it has become critical that effective proxy indicators of species richness are established. This study tests how accurately three potential proxy indicators (generic richness on belt transects, generic richness on point-intercept transects and percent live hard coral cover on point-intercept transects) predict coral species richness at three different locations and two analytical scales. Generic richness (measured on a belt transect) was found to be the most effective predictor variable, with significant positive linear relationships across locations and scales. Percent live hard coral cover consistently performed poorly as an indicator of coral species richness. This study advances the practical framework for optimizing coral reef monitoring programs and empirically demonstrates that generic richness offers an effective way to predict coral species richness with a moderate level of precision. While the accuracy of species richness estimates will decrease in communities dominated by species-rich genera (e.g. Acropora), generic richness provides a useful measure of phylogenetic diversity and incorporating this metric into monitoring programs will increase the likelihood that changes in coral species diversity can be detected.

  14. Predicting coral species richness: the effect of input variables, diversity and scale.

    Directory of Open Access Journals (Sweden)

    Zoe T Richards

    Full Text Available Coral reefs are facing a biodiversity crisis due to increasing human impacts, consequently, one third of reef-building corals have an elevated risk of extinction. Logistic challenges prevent broad-scale species-level monitoring of hard corals; hence it has become critical that effective proxy indicators of species richness are established. This study tests how accurately three potential proxy indicators (generic richness on belt transects, generic richness on point-intercept transects and percent live hard coral cover on point-intercept transects predict coral species richness at three different locations and two analytical scales. Generic richness (measured on a belt transect was found to be the most effective predictor variable, with significant positive linear relationships across locations and scales. Percent live hard coral cover consistently performed poorly as an indicator of coral species richness. This study advances the practical framework for optimizing coral reef monitoring programs and empirically demonstrates that generic richness offers an effective way to predict coral species richness with a moderate level of precision. While the accuracy of species richness estimates will decrease in communities dominated by species-rich genera (e.g. Acropora, generic richness provides a useful measure of phylogenetic diversity and incorporating this metric into monitoring programs will increase the likelihood that changes in coral species diversity can be detected.

  15. Symbolic dynamics marker of heart rate variability combined with clinical variables enhance obstructive sleep apnea screening

    Science.gov (United States)

    Ravelo-García, A. G.; Saavedra-Santana, P.; Juliá-Serdá, G.; Navarro-Mesa, J. L.; Navarro-Esteva, J.; Álvarez-López, X.; Gapelyuk, A.; Penzel, T.; Wessel, N.

    2014-06-01

    Many sleep centres try to perform a reduced portable test in order to decrease the number of overnight polysomnographies that are expensive, time-consuming, and disturbing. With some limitations, heart rate variability (HRV) has been useful in this task. The aim of this investigation was to evaluate if inclusion of symbolic dynamics variables to a logistic regression model integrating clinical and physical variables, can improve the detection of subjects for further polysomnographies. To our knowledge, this is the first contribution that innovates in that strategy. A group of 133 patients has been referred to the sleep center for suspected sleep apnea. Clinical assessment of the patients consisted of a sleep related questionnaire and a physical examination. The clinical variables related to apnea and selected in the statistical model were age (p variable based on non-linear dynamics of HRV (p variables. For diagnostic rule based only on clinical and physical variables, the corresponding area under the receiver operating characteristic (ROC) curve was 0.907 (95% confidence interval (CI) = 0.848, 0.967), (sensitivity 87.10% and specificity 80%). For the model including the average of a symbolic dynamic variable, the area under the ROC curve was increased to 0.941 (95% = 0.897, 0.985), (sensitivity 88.71% and specificity 82.86%). In conclusion, symbolic dynamics, coupled with significant clinical and physical variables can help to prioritize polysomnographies in patients with a high probability of apnea. In addition, the processing of the HRV is a well established low cost and robust technique.

  16. Modeling the BOD of Danube River in Serbia using spatial, temporal, and input variables optimized artificial neural network models.

    Science.gov (United States)

    Šiljić Tomić, Aleksandra N; Antanasijević, Davor Z; Ristić, Mirjana Đ; Perić-Grujić, Aleksandra A; Pocajt, Viktor V

    2016-05-01

    This paper describes the application of artificial neural network models for the prediction of biological oxygen demand (BOD) levels in the Danube River. Eighteen regularly monitored water quality parameters at 17 stations on the river stretch passing through Serbia were used as input variables. The optimization of the model was performed in three consecutive steps: firstly, the spatial influence of a monitoring station was examined; secondly, the monitoring period necessary to reach satisfactory performance was determined; and lastly, correlation analysis was applied to evaluate the relationship among water quality parameters. Root-mean-square error (RMSE) was used to evaluate model performance in the first two steps, whereas in the last step, multiple statistical indicators of performance were utilized. As a result, two optimized models were developed, a general regression neural network model (labeled GRNN-1) that covers the monitoring stations from the Danube inflow to the city of Novi Sad and a GRNN model (labeled GRNN-2) that covers the stations from the city of Novi Sad to the border with Romania. Both models demonstrated good agreement between the predicted and actually observed BOD values.

  17. Predictor Variables and Screening Protocol for Depressive and Anxiety Disorders in Cancer Outpatients.

    Directory of Open Access Journals (Sweden)

    Manuela Polidoro Lima

    Full Text Available Cancer patients are at increased risk of persistent depressive and anxiety symptoms and disorders compared to the general population. However, these issues are not always identified, which may worsen the prognosis and increase morbidity and mortality. Therefore, the objectives of this study are to identify predictor variables (demographic and clinical for the development of mood and anxiety disorders in cancer outpatients and to propose a probabilistic screening protocol considering these variables and certain standardized screening instruments.A total of 1,385 adults, of both genders, receiving outpatient cancer care were evaluated using a questionnaire and screening instruments. Thereafter, 400 of these subjects responded to the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID-IV by telephone to confirm or rule out the presence of a Current Major Depressive Episode (CMDE or Anxiety Disorder (AD.Of the patients surveyed, 64% met the criteria for CMDE and 41% for AD. Female gender was found to be a risk factor for both disorders, and the presence of previous psychiatric history and marital status (divorced and widowed were risk factors for anxiety disorders. When scoring above the recommended cutoff score, the screening instruments also indicated a risk of the studied disorders. Based on these findings, a screening protocol and nomograms were created for the quantification, combination and probabilistic estimate of risk, with accuracy indicators >0.68.The prevalence rates for the disorders under study are extremely high in cancer patients. The use of the proposed protocol and nomogram can facilitate rapid and wide screening, thus refining triage and supporting the establishment of criteria for referral to mental health professionals, so that patients can be properly diagnosed and treated.

  18. Neural network with a self-selection ability of input variables for a nonlinear system identification; Nyuryoku hensu no jiko sentaku noryoku wo sonaeta hisenkei system dotei yo neural network

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, T. [School of Medical Sciences, The University of Tokushima., Tokushima (Japan)

    1997-08-31

    When neural network is applied to identification problem with complex structure, structure of the network becomes larger in its scale and more complex as its input variables increase, because of necessity on effect of high order in the input variable within the network. In this study, a neural network with self-selection ability of the input variables is proposed. This network can remove the neuron related to the input variables from inner portion of the network according to the prediction error estimation standard and construct a neural network only by means of the neuron related to useful input variables, even when it contains unnecessary variables for its input variable. In this paper, by comparing with identification results obtained by conventional neural network or improved GMDH method, its effectiveness could be elucidated. And, it applied to short-term forecasting problem of air pollution concentration, to compare its estimation accuracy with those of other prediction models. 18 refs., 10 figs., 3 tabs.

  19. Variability of energy input into selected subsystems of the human-glove-tool system: a theoretical study.

    Science.gov (United States)

    Hermann, Tomasz; Dobry, Marian Witalis

    2017-05-31

    This article presents an application of the energy method to assess the energy input introduced into two subsystems of the human-glove-tool system. To achieve this aim, a physical model of the system was developed. This consists of dynamic models of the human body and the glove described in Standard No. ISO 10068:2012, and a model of a hand-held power tool. The energy input introduced into the subsystems, i.e., the human body and the glove, was analysed in the domain of energy and involved calculating three component energy inputs of forces. The energy model was solved using numerical simulation implemented in the MATLAB/simulink environment. This procedure demonstrates that the vibration energy was distributed quite differently in the internal structure of the two subsystems. The results suggest that the operating frequency of the tool has a significant impact on the level of energy inputs transmitted into both subsystems.

  20. Associations between Functional Movement Screen scores and performance variables in surf athletes.

    Science.gov (United States)

    Ferreira da Silva, Bruno A; Clemente, Filipe M; Lourenço Martins, Fernando M

    2017-02-22

    Functional Movement Screen (FMS) have been used to assess the movement patterns in daily sports practice. Some associations between FMS scores and physical variables have been found in some sports. Nevertheless, no study was conducted in surf. Eighteen surf athletes (11 male) participated in the study (18.3 ± 6.3 y; 60.0 ± 9.6 kg; 168.6 ± 8.1 cm). All participants completed anthropometrics, Knee to Wall test, Functional Movement Screen, Isometric Knee Extension, Handgrip, Squat and Countermovement Jump. Based on that, this study investigated: 1) the variance of FMS scores between gender; 2) the association between FMS scores and physical variables of strength of upper and lower limbs, power of lower limbs and anthropometric variables; and 3) which FMS scores best explain the physical performance variables. The analysis of comparison between gender of each item of FMS showed significant statistical differences only in Trunk Stability Push-Up (p = 0.01, ES=0.141). Kendall's Tau b correlation test between FMS scores and physical variables, revealed significant associations. After performed the stepwise multiple linear regression FMS Deep Squat and Trunk Stability Push-Up explains 57% of Knee to Wall test - right side and the model is statistically significant (F(2. 15) = 13.097; p-value = 0.001). In Squat Jump (height) the results show that FMS Trunk Stability Push-Up explains 50.3% of this dimension and the model is statistically significant (F(1. 16) = 18.182; p-value = 0.001). FMS individual scores seems to better explain physical variables than total score. Only Trunk Stability Push-Up test seems to be a reliable indicator to predict physical performance in surf athletes.

  1. Android multi-touch screen input system design and realization%Android多点触摸屏输入系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    石坚; 白瑞林; 邹骏宇; 马涛

    2012-01-01

    为了设计实用新型工业人机界面,提出了一种基于五点触摸校正和中位数均值滤波的Android多点触摸输入系统设计方法.采用五点触摸校正,根据触摸屏上采样的五个点,计算出校正系数,作为触屏校正参数;在mXT224控制器处理基础上,采用中位数均值阀限滤波,滤除触摸系统高斯噪声与尖峰噪声,并结合触摸校正参数校正输入坐标,逐级上传输入坐标信息,最终传递给上层应用程序.测试表明,基于优化的Android多点触摸输入系统在噪声很大环境下能够维持高信噪比(超过80∶i),并支持带手套或触笔触摸输入,反应时间小于10 ms,符合工业人机界面(HMI)设计要求.%In order to design a new practical industrial human-machine interface, a touch input system design way based on a five-point touch calibration and a median average filter algorithm is proposed. The system uses a five-point touch calibration to calculate the correction factor based on a sampling of five points of the touch screen as a touch-screen calibration parameters; based on mXT224 controller, it utilizes the average median threshold way to filter white Gaussian noise and spike noise, and then effectively corrects calculation of multi-point input, step by step uploads input coordinate information, and ultimately passes information to the upper application. The tests show that the noisy environment based on the optimization of the Android multi-touch input system can maintain a high signal to noise ratio (over 80: 1), and support with gloves or a stylus to touch input with the response time of less than 10 ms, which is accorded with the industrial Human-Machine Interface (HMI) design requirements.

  2. APPLICATION OF FRF ESTIMATOR BASED ON ERRORS-IN-VARIABLES MODEL IN MULTI-INPUT MULTI-OUTPUT VIBRATION CONTROL SYSTEM

    Institute of Scientific and Technical Information of China (English)

    GUAN Guangfeng; CONG Dacheng; HAN Junwei; LI Hongren

    2007-01-01

    The FRF estimator based on the errors-in-variables (EV) model of multi-input multi-output (MIMO) System is presented to reduce the bias error of FRF Hl estimator. The FRF Hl estimator is influenced by the noises in the inputs of the System and generates an under-estimation of the true FRF. The FRF estimator based on the EV model takes into account the errors in both the inputs and Outputs of the System and would lead to more accurate FRF estimation. The FRF estimator based on the EV model is applied to the waveform replication on the 6-DOF (degree-of-freedom) hydraulic Vibration table. The result shows that it is favorable to improve the control precision of the MIMO Vibration control system.

  3. Measurement method for urine puddle depth in dairy cow houses as input variable for ammonia emission modelling

    NARCIS (Netherlands)

    Snoek, J.W.; Stigter, J.D.; Ogink, Nico; Groot Koerkamp, P.W.G.

    2015-01-01

    Dairy cow houses are a major contributor to ammonia (NH3) emission in many European countries. To understand and predict NH3 emissions from cubicle dairy cow houses a mechanistic model was developed and a sensitivity analysis was performed to assess the contribution to NH3 emission of each input var

  4. Measurement method for urine puddle depth in dairy cow houses as input variable for ammonia emission modelling

    NARCIS (Netherlands)

    Snoek, J.W.; Stigter, J.D.; Ogink, Nico; Groot Koerkamp, P.W.G.

    2015-01-01

    Dairy cow houses are a major contributor to ammonia (NH3) emission in many European countries. To understand and predict NH3 emissions from cubicle dairy cow houses a mechanistic model was developed and a sensitivity analysis was performed to assess the contribution to NH3 emission of each input

  5. A comparison of fixed and variable kVp technique protocols for film-screen mammography.

    Science.gov (United States)

    McParland, B J; Boyd, M M

    2000-06-01

    Mammographic image quality, contrast and dose for a variable tube potential (kVp) technique protocol for film-screen mammography have been investigated. In this protocol, the tube potential is increased for larger breast thicknesses. Comparisons were made with fixed kVp protocols, in which the tube potential is kept constant and the breast thickness compensated for by prolonging the exposure ("fixed kVp" protocol). All measurements were performed on a mammography unit with a molybdenum target and filter. Image quality was quantified by image contrast, image detail detection and the minimum detectable dimension of low contrast objects. It was demonstrated that for a compressed breast thickness of less than about 40 mm, varying the tube potential had a negligible effect upon dose but a significant effect upon image quality. For a compressed breast thickness greater than about 60 mm, the effect of the tube potential upon image quality was much reduced; however, the effect upon dose was significantly greater. The variable kVp protocol takes advantage of this feature to yield a significantly lower dose for thicker breasts with a small reduction in image quality, often only within experimental uncertainty. For an exposure under automatic exposure control, increasing the tube potential from 26 kVp to 30 kVp for a breast of a reference tissue composition (50% adipose and 50% glandular) with a compressed thickness of 60 mm reduced the mean glandular dose from 6 mGy to 3.9 mGy (-35%), but increased the minimum detectable dimension of a low contrast mass from 0.8 (+/- 0.1) mm to 1.1 (+/- 0.1) mm. Adopting a variable kVp protocol led to a median patient mean glandular dose per film of 2.7 mGy, nearly independent of compressed breast thickness. In our survey, the mean age of women presenting for mammography is younger and the mean compressed breast thickness is less than reported from screening centres. This suggests that there will be a higher proportion of denser, glandular

  6. Derivation and analysis on the analytical structure of interval type-2 fuzzy controller with two nonlinear fuzzy sets for each input variable

    Institute of Scientific and Technical Information of China (English)

    Bin-bin LEI; Xue-chao DUAN; Hong BAO; Qian XU

    2016-01-01

    Type-2 fuzzy controllers have been mostly viewed as black-box function generators. Revealing the analytical struc-ture of any type-2 fuzzy controller is important as it will deepen our understanding of how and why a type-2 fuzzy controller functions and lay a foundation for more rigorous system analysis and design. In this study, we derive and analyze the analytical structure of an interval type-2 fuzzy controller that uses the following identical elements: two nonlinear interval type-2 input fuzzy sets for each variable, four interval type-2 singleton output fuzzy sets, a Zadeh AND operator, and the Karnik-Mendel type reducer. Through dividing the input space of the interval type-2 fuzzy controller into 15 partitions, the input-output relationship for each local region is derived. Our derivation shows explicitly that the controller is approximately equivalent to a nonlinear proportional integral or proportional differential controller with variable gains. Furthermore, by comparing with the analytical structure of its type-1 counterpart, potential advantages of the interval type-2 fuzzy controller are analyzed. Finally, the reliability of the analysis results and the effectiveness of the interval type-2 fuzzy controller are verified by a simulation and an experiment.

  7. Effect of variable annual precipitation and nutrient input on nitrogen and phosphorus transport from two Midwestern agricultural watersheds

    Science.gov (United States)

    Kalkhoff, Stephen J.; Hubbard, Laura E.; Tomer, Mark D.; James, D.E.

    2016-01-01

    Precipitation patterns and nutrient inputs affect transport of nitrate (NO3-N) and phosphorus (TP) from Midwest watersheds. Nutrient concentrations and yields from two subsurface-drained watersheds, the Little Cobb River (LCR) in southern Minnesota and the South Fork Iowa River (SFIR) in northern Iowa, were evaluated during 1996–2007 to document relative differences in timings and amounts of nutrients transported. Both watersheds are located in the prairie pothole region, but the SFIR exhibits a longer growing season and more livestock production. The SFIR yielded significantly more NO3-N than the LCR watershed (31.2 versus 21.3 kg NO3-N ha− 1 y− 1). The SFIR watershed also yielded more TP than the LCR watershed (1.13 versus 0.51 kg TP ha− 1 yr− 1), despite greater TP concentrations in the LCR. About 65% of NO3-N and 50% of TP loads were transported during April–June, and < 20% of the annual loads were transported later in the growing season from July–September. Monthly NO3-N and TP loads peaked in April from the LCR but peaked in June from the SFIR; this difference was attributed to greater snowmelt runoff in the LCR. The annual NO3-N yield increased with increasing annual runoff at a similar rate in both watersheds, but the LCR watershed yielded less annual NO3-N than the SFIR for a similar annual runoff. These two watersheds are within 150 km of one another and have similar dominant agricultural systems, but differences in climate and cropping inputs affected amounts and timing of nutrient transport.

  8. Effect of the spatiotemporal variability of rainfall inputs in water quality integrated catchment modelling for dissolved oxygen concentrations

    Science.gov (United States)

    Moreno Ródenas, Antonio Manuel; Cecinati, Francesca; ten Veldhuis, Marie-Claire; Langeveld, Jeroen; Clemens, Francois

    2016-04-01

    Maintaining water quality standards in highly urbanised hydrological catchments is a worldwide challenge. Water management authorities struggle to cope with changing climate and an increase in pollution pressures. Water quality modelling has been used as a decision support tool for investment and regulatory developments. This approach led to the development of integrated catchment models (ICM), which account for the link between the urban/rural hydrology and the in-river pollutant dynamics. In the modelled system, rainfall triggers the drainage systems of urban areas scattered along a river. When flow exceeds the sewer infrastructure capacity, untreated wastewater enters the natural system by combined sewer overflows. This results in a degradation of the river water quality, depending on the magnitude of the emission and river conditions. Thus, being capable of representing these dynamics in the modelling process is key for a correct assessment of the water quality. In many urbanised hydrological systems the distances between draining sewer infrastructures go beyond the de-correlation length of rainfall processes, especially, for convective summer storms. Hence, spatial and temporal scales of selected rainfall inputs are expected to affect water quality dynamics. The objective of this work is to evaluate how the use of rainfall data from different sources and with different space-time characteristics affects modelled output concentrations of dissolved oxygen in a simplified ICM. The study area is located at the Dommel, a relatively small and sensitive river flowing through the city of Eindhoven (The Netherlands). This river stretch receives the discharge of the 750,000 p.e. WWTP of Eindhoven and from over 200 combined sewer overflows scattered along its length. A pseudo-distributed water quality model has been developed in WEST (mikedhi.com); this is a lumped-physically based model that accounts for urban drainage processes, WWTP and river dynamics for several

  9. Using the Iterative Input variable Selection (IIS) algorithm to assess the relevance of ENSO teleconnections patterns on hydro-meteorological processes at the catchment scale

    Science.gov (United States)

    Beltrame, Ludovica; Carbonin, Daniele; Galelli, Stefano; Castelletti, Andrea

    2014-05-01

    Population growth, water scarcity and climate change are three major factors making the understanding of variations in water availability increasingly important. Therefore, reliable medium-to-long range forecasts of streamflows are essential to the development of water management policies. To this purpose, recent modelling efforts have been dedicated to seasonal and inter-annual streamflow forecasts based on the teleconnection between "at-site" hydro-meteorological processes and low frequency climate fluctuations, such as El Niño Southern Oscillation (ENSO). This work proposes a novel procedure for first detecting the impact of ENSO on hydro-meteorological processes at the catchment scale, and then assessing the potential of ENSO indicators for building medium-to-long range statistical streamflow prediction models. Core of this procedure is the adoption of the Iterative Input variable Selection (IIS) algorithm that is employed to find the most relevant forcings of streamflow variability and derive predictive models based on the selected inputs. The procedure is tested on the Columbia (USA) and Williams (Australia) Rivers, where ENSO influence has been well-documented, and then adopted on the unexplored Red River basin (Vietnam). Results show that IIS outcomes on the Columbia and Williams Rivers are consistent with the results of previous studies, and that ENSO indicators can be effectively used to enhance the streamflow forecast models capabilities. The experiments on the Red River basin show that the ENSO influence is less pronounced, inducing little effects on the basin hydro-meteorological processes.

  10. The impacts of interannual climate variability and agricultural inputs on water footprint of crop production in an irrigation district of China.

    Science.gov (United States)

    Sun, Shikun; Wu, Pute; Wang, Yubao; Zhao, Xining; Liu, Jing; Zhang, Xiaohong

    2013-02-01

    Irrigation plays an increasing important role in agriculture of China. The assessment of water resources utilization during agricultural production process will contribute to improving agricultural water management practices for the irrigation districts. The water footprint provides a new approach to assessing the agricultural water utilization. The present paper put forward a modified calculation method to quantify the water footprint of crop. On this basis, this paper calculated the water footprint of major crop in Hetao irrigation district, China. Then, it evaluated the influencing factors that caused the variability of crop water footprint during the study period. Results showed that: 1) the annual average water footprint of integrated-crop production in Hetao irrigation district was 3.91 m(3)kg(-1) (90.91% blue water and 9.09% green water). The crop production in the Hetao irrigation district mainly relies on blue water; 2) under the integrated influences of interannual climate variability and variation of agricultural inputs, the water footprint of integrated-crop production displayed a decreasing trend; 3) the contribution rate of the climatic factors to the variation of water footprint was only -6.90%, while the total contribution rate of the agricultural inputs factors was -84.31%. The results suggest that the water footprint of crop mainly depends on agricultural management rather than the regional climate and its variation. The results indicated that the water footprint of a crop could be controlled at a reasonable level by better management of all agricultural inputs and the improvement of water use efficiency in agriculture. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Polishing tool and the resulting TIF for three variable machine parameters as input for the removal simulation

    Science.gov (United States)

    Schneider, Robert; Haberl, Alexander; Rascher, Rolf

    2017-06-01

    The trend in the optic industry shows, that it is increasingly important to be able to manufacture complex lens geometries on a high level of precision. From a certain limit on the required shape accuracy of optical workpieces, the processing is changed from the two-dimensional to point-shaped processing. It is very important that the process is as stable as possible during the in point-shaped processing. To ensure stability, usually only one process parameter is varied during processing. It is common that this parameter is the feed rate, which corresponds to the dwell time. In the research project ArenA-FOi (Application-oriented analysis of resource-saving and energy-efficient design of industrial facilities for the optical industry), a touching procedure is used in the point-attack, and in this case a close look is made as to whether a change of several process parameters is meaningful during a processing. The ADAPT tool in size R20 from Satisloh AG is used, which is also available for purchase. The behavior of the tool is tested under constant conditions in the MCP 250 CNC by OptoTech GmbH. A series of experiments should enable the TIF (tool influence function) to be determined using three variable parameters. Furthermore, the maximum error frequency that can be processed is calculated as an example for one parameter set and serves as an outlook for further investigations. The test results serve as the basic for the later removal simulation, which must be able to deal with a variable TIF. This topic has already been successfully implemented in another research project of the Institute for Precision Manufacturing and High-Frequency Technology (IPH) and thus this algorithm can be used. The next step is the useful implementation of the collected knowledge. The TIF must be selected on the basis of the measured data. It is important to know the error frequencies to select the optimal TIF. Thus, it is possible to compare the simulated results with real measurement

  12. Patient variables and referral paradigms associated with osteoporosis screening and treatment in neurosurgical patients undergoing kyphoplasty.

    Science.gov (United States)

    Morr, Simon; Shakir, Hakeem J; Lipinski, Lindsay J; Dimopoulos, Vassilios G; Leonardo, Jody; Pollina, John

    2015-12-01

    OBJECT Vertebral fractures are the most common osteoporotic fracture. Bone density testing and medical treatment with bisphosphonates or parathormone are recommended for all patients with an osteoporotic fracture diagnosis. Inadequate testing and treatment of patients presenting with low-impact fractures have been reported in various specialties. Similar data are not available from academic neurosurgery groups. The authors assessed compliance with treatment and testing of osteoporosis in patients with vertebral compression fractures evaluated by the authors' academic neurosurgery service, and patient variable and health-systems factors associated with improved compliance. METHODS Data for patients who underwent percutaneous kyphoplasty for compression fractures was retrospectively collected. Diagnostic and medical interventions were tabulated. Pre-, intra-, and posthospital factors that had been theorized to affect the compliance of patients with osteoporosis-related therapies were tabulated and statistically analyzed. RESULTS Less than 50% of patients with kyphoplasty received such therapies. Age was not found to correlate with other variables. Referral from a specialist rather than a primary care physician was associated with a higher rate of bone density screening, as well as vitamin D and calcium therapy, but not bisphosphonate/parathormone therapy. Patients who underwent preoperative evaluation by their primary care physician were significantly more likely to receive bisphosphonates compared with those only evaluated by a hospitalist. Patients with unprovoked fractures were more likely to undergo multiple surgeries compared with those with minor trauma. CONCLUSIONS These results suggest poor compliance with current standard of care for medical therapies in patients with osteoporotic compression fractures undergoing kyphoplasty under the care of an academic neurosurgery service.

  13. Screening for haplotypic variability within Oesophagostomum bifurcum (Nematoda) employing a single-strand conformation polymorphism approach.

    Science.gov (United States)

    de Gruijter, J M; Polderman, A M; Zhu, X Q; Gasser, R B

    2002-06-01

    Genetic markers in the mitochondrial genome have proven useful for population genetic studies because of their maternal inheritance and relatively high evolutionary rates. In this study, we exploited the high resolution capacity of PCR-coupled single-strand conformation polymorphism (SSCP) to screen for sequence variation in part of the cytochrome c oxidase subunit 1 gene (p cox 1) among individuals of the parasitic nematode, Oesophagostomum bifurcum from human or Mona monkey hosts from Africa. SSCP analysis revealed distinct profiles among some of the individuals, and subsequent sequence analysis of representative samples defined 10 different haplotypes. For comparative purposes, the p cox 1 sequences for representatives of four other species of Oesophagostomum from livestock were included. While there were high levels (11.5-13.7%) of sequence difference among the latter species, there was no fixed nucleotide difference between O. bifurcum individuals from humans and those from monkeys. The data support the proposal that O. bifurcum from the two primate hosts represents a single species and that the haplotypic variability in p cox 1 represents population variation. The results reinforce the usefulness of the SSCP-sequencing approach for studying genetic variation in nematode populations using mitochondrial markers.

  14. High resolution variability in the Quaternary Indian monsoon inferred from records of clastic input and paleo-production recovered during IODP Expedition 355

    Science.gov (United States)

    Hahn, Annette; Lyle, Mitchell; Kulhanek, Denise; Ando, Sergio; Clift, Peter

    2016-04-01

    The sediment cores obtained from the Indus fan at Site U1457 during Expedition 355 of the International Ocean Discovery Program (IODP) contain a ca. 100m spliced section covering the past ca. 1Ma. We aim to make use of this unique long, mostly continuous climate archive to unravel the millennial scale atmospheric and oceanic processes linked to changes in the Indian monsoon climate over the Quaternary glacial-interglacial cycles. Our aim is to fill this gap using fast, cost-efficient methods (Fourier Transform Infrared Spectroscopy [FTIRS] and X-ray Fluorescence [XRF] scanning) which allow us to study this sequence at a millennial scale resolution (2-3cm sampling interval). An important methodological aspect of this study is developing FTIRS as a method for the simultaneous estimation of the sediment total inorganic carbon and organic carbon content by using the specific fingerprint absorption spectra of minerals (e.g. calcite) and organic sediment components. The resulting paleo-production proxies give indications of oceanic circulation patterns and serve as a direct comparison to the XRF scanning data. Initial results show that variability in paleo-production is accompanied by changes in the quantity and composition of clastic input to the site. Phases of increased deposition of terrigenous material are enriched in K, Al, Fe and Si. Both changes in the weathering and erosion focus areas affect the mineralogy and elemental composition of the clastic input as grain size and mineralogical changes are reflected in the ratios of lighter to heavier elements. Furthermore, trace element compositions (Zn, Cu, Mn) give indications of diagenetic processes and contribute to the understanding of the depositional environment. The resulting datasets will lead to a more comprehensive understanding of the interplay of the local atmospheric and oceanic circulation processes over glacial-interglacial cycles; an essential prerequisite for regional predictions of global climate

  15. Availability and variability in guidelines on diabetic retinopathy screening in Asian countries.

    Science.gov (United States)

    Wang, Louis Zizhao; Cheung, Carol Y; Tapp, Robyn J; Hamzah, Haslina; Tan, Gavin; Ting, Daniel; Lamoureux, Ecosse; Wong, Tien Yin

    2017-10-01

    Diabetic retinopathy (DR) is a blinding yet treatable complication of diabetes. DR screening is highly cost-effective at reducing blindness. Amidst the rapidly growing diabetic population in Asia, the prevalence of DR in the region is relatively less well known. To review existing national DR screening guidelines of 50 countries in Asia, compare them against the International Council of Ophthalmology (ICO) guideline, and summarise the prevalence rates of DR and sight-threatening DR (STDR) in these countries. We systematically searched for published guidelines from the National Guideline Clearinghouse and other databases, and contacted local diabetic and ophthalmological associations of all 50 Asian countries. Eleven Asian countries have published relevant guidelines, nine of which pertain to general diabetes care and two are DR-specific, covering less than half of Asia's population. The median DR prevalence among patients with diabetes is 30.5% (IQR: 23.2%-36.8%), similar to the USA and the UK. However, rates of STDR are consistently higher. All guidelines from the 11 Asian countries fulfil the ICO standard on when to start and repeat screening, except for screening interval for pregnant patients. However, only 2 of the 11 guidelines fulfil the ICO referral criteria and 6 partially fulfil. A third of the recommendations on screening process, equipment and personnel is either unavailable or incomplete. Countries in Asia need to establish more comprehensive and evidence-based DR screening guidelines to facilitate the execution of robust screening programmes that could help reduce DR-related blindness, improve patient outcomes and reduce healthcare costs. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  16. Forecasting Urban Water Demand via Machine Learning Methods Coupled with a Bootstrap Rank-Ordered Conditional Mutual Information Input Variable Selection Method

    Science.gov (United States)

    Adamowski, J. F.; Quilty, J.; Khalil, B.; Rathinasamy, M.

    2014-12-01

    This paper explores forecasting short-term urban water demand (UWD) (using only historical records) through a variety of machine learning techniques coupled with a novel input variable selection (IVS) procedure. The proposed IVS technique termed, bootstrap rank-ordered conditional mutual information for real-valued signals (brCMIr), is multivariate, nonlinear, nonparametric, and probabilistic. The brCMIr method was tested in a case study using water demand time series for two urban water supply system pressure zones in Ottawa, Canada to select the most important historical records for use with each machine learning technique in order to generate forecasts of average and peak UWD for the respective pressure zones at lead times of 1, 3, and 7 days ahead. All lead time forecasts are computed using Artificial Neural Networks (ANN) as the base model, and are compared with Least Squares Support Vector Regression (LSSVR), as well as a novel machine learning method for UWD forecasting: the Extreme Learning Machine (ELM). Results from one-way analysis of variance (ANOVA) and Tukey Honesty Significance Difference (HSD) tests indicate that the LSSVR and ELM models are the best machine learning techniques to pair with brCMIr. However, ELM has significant computational advantages over LSSVR (and ANN) and provides a new and promising technique to explore in UWD forecasting.

  17. Antibody screening tests variably overestimate the prevalence of hepatitis C virus infection among HIV-infected adults in Ghana.

    Science.gov (United States)

    King, S; Adjei-Asante, K; Appiah, L; Adinku, D; Beloukas, A; Atkins, M; Sarfo, S F; Chadwick, D; Phillips, R O; Geretti, A M

    2015-05-01

    HIV coinfection with HCV has been poorly studied in sub-Saharan Africa, and the reliability of available seroprevalence estimates remains uncertain. The study aim was to determine HCV RNA prevalence in HIV-infected subjects receiving care in Kumasi, Ghana, and relate the findings to HCV antibody detection. From a population of 1520 HIV-infected adults, all HBsAg-positive subjects (n = 236) and a random subset of HBsAg-negative subject (n = 172) were screened for HCV RNA using pooled plasma; positive samples were genotyped by core and NS5B sequencing. HCV antibodies were detected by three commercial screening assays and confirmed by the line immunoassay. HCV RNA was detected in 4/408 subjects (1.0%, 95% confidence interval 0.0-1.9%), comprising 3/236 (1.3%; 0.0-2.8%) HBsAg-positive and 1/172 (0.6%; 0.0-1.8%) HBsAg-negative subjects. HCV RNA-positive subjects showed reactivity in all three antibody screening assays. Among HCV RNA-negative subjects, 5/67 (7.5%), 5/67 (7.5%) and 19/67 (28.4%) showed antibody reactivity by each screening assay, respectively, including two (3.0%) with reactivity by all three assays. Only one sample (1.5%) had confirmed antibody reactivity by line immunoassay indicating past HCV infection. HCV-positive subjects (three males, two females) were aged 30-46 years, by questionnaire-based interview reported surgical procedures and blood transfusion as risk factors for infection. HCV genotypes were 2 (subtypes 2j, 2l, 2k/unassigned) and 1 (subtype unassigned). Without further testing, HCV antibody screening assays variably overestimated HCV prevalence among HIV-infected subjects in Ghana. These findings inform the interpretation of previous seroprevalence estimates based upon screening assays alone.

  18. Variable Quality and Readability of Patient-oriented Websites on Colorectal Cancer Screening.

    Science.gov (United States)

    Schreuders, Eline H; Grobbee, Esmée J; Kuipers, Ernst J; Spaander, Manon C W; Veldhuyzen van Zanten, Sander J O

    2017-01-01

    The efficacy of colorectal cancer (CRC) screening is dependent on participation and subsequent adherence to surveillance. The internet increasingly is used for health information and is important to support decision making. We evaluated the accuracy, quality, and readability of online information on CRC screening and surveillance. A Website Accuracy Score and Polyp Score were developed, which awarded points for various aspects of CRC screening and surveillance. Websites also were evaluated using validated internet quality instruments (Global Quality Score, LIDA, and DISCERN), and reading scores. Two raters independently assessed the top 30 websites appearing on Google.com. Portals, duplicates, and news articles were excluded. Twenty websites were included. The mean website accuracy score was 26 of 44 (range, 9-41). Websites with the highest scores were www.cancer.org, www.bowelcanceraustralia.org, and www.uptodate.com. The median polyp score was 3 of 10. The median global quality score was 3 of 5 (range, 2-5). The median overall LIDA score was 74% and the median DISCERN score was 45, both indicating moderate quality. The mean Flesch-Kincaid grade level was 11th grade, rating the websites as difficult to read, 30% had a reading level acceptable for the general public (Flesch Reading Ease > 60). There was no correlation between the Google rank and the website accuracy score (rs = -0.31; P = .18). There is marked variation in quality and readability of websites on CRC screening. Most websites do not address polyp surveillance. The poor correlation between quality and Google ranking suggests that screenees will miss out on high-quality websites using standard search strategies. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.

  19. The Association between Anthropometric Variables, Functional Movement Screen Scores and 100 m Freestyle Swimming Performance in Youth Swimmers

    OpenAIRE

    Daisy Bond; Laura Goodson; Samuel W. Oxford; Nevill, Alan M.; Michael J. Duncan

    2015-01-01

    This study examined the association between anthropometric variables, Functional Movement Screen (FMS) scores and 100 m freestyle swimming performance in early adolescent swimmers. Fifty competitive, national level, youth swimmers (21 males, 29 females, mean age ± SD = 13.5 ± 1.5 years, age range 11–16 years) performed an “all-out” 100 m freestyle (front crawl) swim as fast as they could in a 50 m pool. A median divide for 100 m timed swim was also used to divide the sample into faster or slo...

  20. Screening of variable importance for optimizing electrodialytic remediation of heavy metals from polluted harbour sediments

    DEFF Research Database (Denmark)

    Pedersen, Kristine B.; Lejon, Tore; Ottosen, Lisbeth M.

    2015-01-01

    Using multivariate design and modelling, the optimal conditions for electrodialytic remediation (EDR) of heavy metals were determined for polluted harbour sediments from Hammerfest harbour located in the geographic Arctic region of Norway. The comparative importance of the variables, current...... density, remediation time, light/no light, the liquid-solid ratio and stirring rate of the sediment suspension, was determined in 15 laboratory-scale EDR experiments by projection to latent structures (PLS). The relation between the X matrix (experimental variables) and the Y matrix (removal efficiencies...

  1. Life cycle assessment of intensive striped catfish farming in the Mekong Delta for screening hotspots as input to environmental policy and research agenda

    NARCIS (Netherlands)

    Bosma, R.H.; Pham Thi Ahn,; Potting, J.

    2011-01-01

    Purpose Intensive striped catfish production in the Mekong Delta has, in recent years, raised environmental concerns. We conducted a stakeholder-based screening life cycle assessment (LCA) of the intensive farming system to determine the critical environmental impact and their causative processes in

  2. Life cycle assessment of intensive striped catfish farming in the Mekong Delta for screening hotspots as input to environmental policy and research agenda

    OpenAIRE

    2011-01-01

    Purpose Intensive striped catfish production in the Mekong Delta has, in recent years, raised environmental concerns. We conducted a stakeholder-based screening life cycle assessment (LCA) of the intensive farming system to determine the critical environmental impact and their causative processes in producing striped catfish. Additional to the LCA, we assessed water use and flooding hazards in the Mekong Delta. Materials and methods The goal and scope of the LCA were defined in a stakeholder ...

  3. Screening of Problematic Internet Use Among Spanish Adolescents: Prevalence and Related Variables.

    Science.gov (United States)

    Gómez, Patricia; Rial, Antonio; Braña, Teresa; Golpe, Sandra; Varela, Jesús

    2017-04-01

    The opportunities and challenges related to Internet use continue to grow, as well as the social concern around problematic Internet use (PIU), online risky behaviors, and the intensive use of Internet, mainly among adolescents. The aim of this study was to conduct a general screening of PIU in a large sample of school-based adolescents in Spain (n = 40,955), providing updated prevalence data of PIU and different online risky practices, as well as rates of Internet and social network use. Differences between problematic and nonproblematic users were explored in terms of demographics, parental control, and motivations for using. The association between PIU and the involvement in other online risky behaviors was also analyzed, as well as the role of intensive use. The findings show that the global prevalence of PIU among Spanish adolescents is 16.3 percent although this is higher among females, those in their late teens, intensive users, and those without parental control. Logistic regression confirmed that both PIU and intensive use are risk factors for being involved in any online risky behavior. A tentative explanation could be that there is a common deficit of personal and social skills underlying PIU, intensive use, and most online risky practices. From our perspective, value-based education and life skills training are the best way to reach responsible and sensible use of Internet among adolescents. Parents, schools, institutions, and adolescents themselves are called upon to actively engage in facing this problem.

  4. Phytochemical screening and chemical variability in volatile oils of aerial parts of Morinda morindoides.

    Science.gov (United States)

    Kiazolu, J Boima; Intisar, Azeem; Zhang, Lingyi; Wang, Yun; Zhang, Runsheng; Wu, Zhongping; Zhang, Weibing

    2016-10-01

    Morinda morindoides is an important Liberian traditional medicine for the treatment of malaria, fever, worms etc. The plant was subjected to integrated approaches including phytochemical screening and gas chromatography mass spectrometry (GC-MS) analyses. Phytochemical investigation of the powdered plant revealed the presence of phenolics, tannins, flavonoids, saponins, terpenes, steroidal compounds and volatile oil. Steam distillation followed by GC-MS resulted in the identification of 47 volatiles in its aerial parts: 28 were in common including various bioactive volatiles. Major constituents of leaves were phytol (43.63%), palmitic acid (8.55%) and geranyl linalool (6.95%) and stem were palmitic acid (14.95%), eicosane (9.67%) and phytol (9.31%), and hence, a significant difference in the percentage composition of aerial parts was observed. To study seasonal changes, similarity analysis was carried out by calculating correlation coefficient (r) and vector angle cosine (z) that were more than 0.91 for stem-to-stem and leaf-to-leaf batches indicating considerable consistency.

  5. Screening of Catalyst and Important Variable for The Esterification of Acrylic Acid with 2 Ethylhexanol

    Science.gov (United States)

    Ahmad, M. A. A.; Chin, S. Y.

    2017-06-01

    The global demand of 2-ethylhexyl acrylate (2EHA) market has witnessed a significant growth in the past few years and this growth is anticipated to increase in the coming years. 2EHA is one of the basic organic building blocks that mainly used in the production of coatings, adhesives, superabsorbents, thickeners and plastic additives. Homogenous acid-catalysed esterification of acrylic acid (AA) with 2-ethylhexanol (2EH) is commonly used for the production of 2EHA. The homogeneous catalysts such as sulfuric and para-toluene sulfonic acid have resulted the costly and complicated downstream process that generates acidic, corrosive and non-environmental friendly waste. Therefore, it is importance to develop a cheaper process that employing heterogeneous catalysts and alternative raw material from wastewater containing acrylic acid. In this research, the study for the esterification of AA with 2EH catalysed by ion-exchange resin was conducted. The best sulfonic acid functional cation-exchange resin among SK104, SK1B, PK208, PK216, PK228, RCP145, and RCP160 was screened. PK208 outperformed the other resins and it was used subsequently in the parametric studies. The effect of important parameters (initial concentration of acrylic acid (AA), temperature, molar ratio of reactant (AA and 2EH), catalyst loading, and polymerisation inhibitor loading) was studied using 2 factorial design to determine the significant parameters to the esterification. It was found that the initial concentration of AA and temperature were most significantly affecting the esterification of AA with 2EH.

  6. Screening of formulation variables for the preparation of poly(epsilon-caprolactone) nanocapsules containing the local anesthetic benzocaine.

    Science.gov (United States)

    Moraes, Carolina Morales; de Matos, Angélica Prado; Grillo, Renato; de Melo, Nathalie F S; de Paula, Eneida; Dias Filho, Newton Luiz; Rosa, André Henrique; Fraceto, Leonardo Fernandes

    2011-03-01

    In this work we describe the screening of four parameters in the preparation, by nanoprecipitation, of poly(epsilon-caprolactone) nanocapsules, used as a drug carrier system for the local anesthetic, benzocaine. A 2(4-1) factorial experimental design was used to study the influence of four different independent variables (polymer, oily phase, Span 60 and Tween 80) on nanocapsule characteristics (size, polydispersion index, zeta potential) and drug loading capability. Best results were obtained using an aqueous formulation comprising 100 mg of polymer, 200 mg of oily phase, 40 mg of Span 60 and 60 mg of Tween 80 in a final volume of 10 mL which produced a colloidal system with particle size of 188 nm, zeta potential -32 mV, polydispersion index 0.07, and benzocaine association efficiency > 87%. These findings open the way for future clinical studies using such formulations.

  7. MRI screening for silicone breast implant rupture: accuracy, inter- and intraobserver variability using explantation results as reference standard

    Energy Technology Data Exchange (ETDEWEB)

    Maijers, M.C.; Ritt, M.J.P.F. [VU University Medical Centre, Department of Plastic, Reconstructive and Hand Surgery, De Boelelaan 1117, PO Box 7057, Amsterdam (Netherlands); Niessen, F.B. [VU University Medical Centre, Department of Plastic, Reconstructive and Hand Surgery, De Boelelaan 1117, PO Box 7057, Amsterdam (Netherlands); Jan van Goyen Clinic, Department of Plastic Surgery, Amsterdam (Netherlands); Veldhuizen, J.F.H. [MRI Centre, Amsterdam (Netherlands); Manoliu, R.A. [MRI Centre, Amsterdam (Netherlands); VU University Medical Centre, Department of Radiology, Amsterdam (Netherlands)

    2014-06-15

    The recall of Poly Implant Prothese (PIP) silicone breast implants in 2010 resulted in large numbers of asymptomatic women with implants who underwent magnetic resonance imaging (MRI) screening. This study's aim was to assess the accuracy and interobserver variability of MRI screening in the detection of rupture and extracapsular silicone leakage. A prospective study included 107 women with 214 PIP implants who underwent explantation preceded by MRI. In 2013, two radiologists blinded for previous MRI findings or outcome at surgery, independently re-evaluated all MRI examinations. A structured protocol described the MRI findings. The ex vivo findings served as reference standard. In 208 of the 214 explanted prostheses, radiologists agreed independently about the condition of the implants. In five of the six cases they disagreed (2.6 %), but subsequently reached consensus. A sensitivity of 93 %, specificity of 93 %, positive predictive value of 77 % and negative predictive value of 98 % was found. The interobserver agreement was excellent (kappa value of 0.92). MRI has a high accuracy in diagnosing rupture in silicone breast implants. Considering the high kappa value of interobserver agreement, MRI appears to be a consistent diagnostic test. A simple, uniform classification, may improve communication between radiologist and plastic surgeon. (orig.)

  8. The Association between Anthropometric Variables, Functional Movement Screen Scores and 100 m Freestyle Swimming Performance in Youth Swimmers

    Directory of Open Access Journals (Sweden)

    Daisy Bond

    2015-01-01

    Full Text Available This study examined the association between anthropometric variables, Functional Movement Screen (FMS scores and 100 m freestyle swimming performance in early adolescent swimmers. Fifty competitive, national level, youth swimmers (21 males, 29 females, mean age ± SD = 13.5 ± 1.5 years, age range 11–16 years performed an “all-out” 100 m freestyle (front crawl swim as fast as they could in a 50 m pool. A median divide for 100 m timed swim was also used to divide the sample into faster or slower groups. Height, body mass, skinfolds and limb lengths were also assessed. Maturation was calculated by proxy using anthropometric measures and participants also undertook the FMS as a measure of functional performance. Backwards linear regression indicated a significant model (p = 0.0001, Adjusted R2 = 0.638 explaining 63.8% of the variance in swim performance with total sum of skinfolds, upper leg length, lower leg length, hand length and total height significantly contributing to the model. Swimmers who were classed as fast had lower total sum of skinfolds (p = 0.005 and higher total FMS score (p = 0.005 compared to their slower peers. In summary, this study indicates that anthropometric variables significantly explained the variance in 100 m freestyle swimming performance in youth swimmers.

  9. Spectral Heart Rate Variability analysis using the heart timing signal for the screening of the Sleep Apnea-Hypopnea Syndrome.

    Science.gov (United States)

    Alvarez-Estevez, Diego; Moret-Bonillo, Vicente

    2016-04-01

    Some approaches have been published in the past using Heart Rate Variability (HRV) spectral features for the screening of Sleep Apnea-Hypopnea Syndrome (SAHS) patients. However there is a big variability among these methods regarding the selection of the source signal and the specific spectral components relevant to the analysis. In this study we investigate the use of the Heart Timing (HT) as the source signal in comparison to the classical approaches of Heart Rate (HR) and Heart Period (HP). This signal has the theoretical advantage of being optimal under the Integral Pulse Frequency Modulation (IPFM) model assumption. Only spectral bands defined as standard for the study of HRV are considered, and for each method the so-called LF/HF and VLFn features are derived. A comparative statistical analysis between the different resulting methods is performed, and subject classification is investigated by means of ROC analysis and a Naïve-Bayes classifier. The standard Apnea-ECG database is used for validation purposes. Our results show statistical differences between SAHS patients and controls for all the derived features. In the subject classification task the best performance in the testing set was obtained using the LF/HF ratio derived from the HR signal (Area under ROC curve=0.88). Only slight differences are obtained due to the effect of changing the source signal. The impact of using the HT signal in this domain is therefore limited, and has not shown relevant differences with respect to the use of the classical approaches of HR or HP.

  10. Enhancing the comparability of costing methods: cross-country variability in the prices of non-traded inputs to health programmes

    Directory of Open Access Journals (Sweden)

    Evans David B

    2006-04-01

    Full Text Available Abstract Background National and international policy makers have been increasing their focus on developing strategies to enable poor countries achieve the millennium development goals. This requires information on the costs of different types of health interventions and the resources needed to scale them up, either singly or in combinations. Cost data also guides decisions about the most appropriate mix of interventions in different settings, in view of the increasing, but still limited, resources available to improve health. Many cost and cost-effectiveness studies include only the costs incurred at the point of delivery to beneficiaries, omitting those incurred at other levels of the system such as administration, media, training and overall management. The few studies that have measured them directly suggest that they can sometimes account for a substantial proportion of total costs, so that their omission can result in biased estimates of the resources needed to run a programme or the relative cost-effectiveness of different choices. However, prices of different inputs used in the production of health interventions can vary substantially within a country. Basing cost estimates on a single price observation runs the risk that the results are based on an outlier observation rather than the typical costs of the input. Methods We first explore the determinants of the observed variation in the prices of selected "non-traded" intermediate inputs to health programmes – printed matter and media advertising, and water and electricity – accounting for variation within and across countries. We then use the estimated relationship to impute average prices for countries where limited data are available with uncertainty intervals. Results Prices vary across countries with GDP per capita and a number of determinants of supply and demand. Media and printing were inelastic with respect to GDP per capita, with a positive correlation, while the utilities

  11. The Screening Tool of Feeding Problems Applied to Children (STEP-CHILD): Psychometric Characteristics and Associations with Child and Parent Variables

    Science.gov (United States)

    Seiverling, Laura; Hendy, Helen M.; Williams, Keith

    2011-01-01

    The present study evaluated the 23-item Screening Tool for Feeding Problems (STEP; Matson & Kuhn, 2001) with a sample of children referred to a hospital-based feeding clinic to examine the scale's psychometric characteristics and then demonstrate how a children's revision of the STEP, the STEP-CHILD is associated with child and parent variables.…

  12. Wind Power Curve Modeling Using Statistical Models: An Investigation of Atmospheric Input Variables at a Flat and Complex Terrain Wind Farm

    Energy Technology Data Exchange (ETDEWEB)

    Wharton, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bulaevskaya, V. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Irons, Z. [Enel Green Power North America, Andover, MA (United States); Qualley, G. [Infigen Energy, Dallas, TX (United States); Newman, J. F. [Univ. of Oklahoma, Norman, OK (United States); Miller, W. O. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-09-28

    The goal of our FY15 project was to explore the use of statistical models and high-resolution atmospheric input data to develop more accurate prediction models for turbine power generation. We modeled power for two operational wind farms in two regions of the country. The first site is a 235 MW wind farm in Northern Oklahoma with 140 GE 1.68 turbines. Our second site is a 38 MW wind farm in the Altamont Pass Region of Northern California with 38 Mitsubishi 1 MW turbines. The farms are very different in topography, climatology, and turbine technology; however, both occupy high wind resource areas in the U.S. and are representative of typical wind farms found in their respective areas.

  13. Optimal Design of a Push-Pull-Forward Half-Bridge (PPFHB) Bidirectional DC–DC Converter With Variable Input Voltage

    DEFF Research Database (Denmark)

    Zhang, Zhe; Thomsen, Ole Cornelius; Andersen, Michael A. E.

    2012-01-01

    This paper presents a low-cost bidirectional isolated dc–dc converte, derived from dual-active-bridge converter for the power sources with variable output voltage like supercapacitors. The proposed converter consists of push-pull-forward circuit half-bridge circuit (PPFHB) and a high-frequency tr...... by digital signal processor for comparison purpose. Detailed test results verify the theoretical analysis and demonstrate the validity of optimization design method....

  14. Hf isotope evidence for variable slab input and crustal addition in basalts and andesites of the Taupo Volcanic Zone, New Zealand

    DEFF Research Database (Denmark)

    Waight, Tod Earle; Troll, Valentin R.; Gamble, J.A.

    2017-01-01

    variations likely represent variability in primary magma compositions as a result of different degrees of sediment addition at the slab-wedge interface. Coupled variations in isotopic composition, LILE/HFSE ratios (e.g. Rb/Zr and Ba/La) and SiO2 also clearly indicate that shallower level crustal interactions......Crustal contamination complicates the identification of primary mantle-derived magma compositions in Continental arcs. However,when crustal processes and components arewell characterised, it is possible to extrapolate through continental arc magma compositional arrays towards the Hf and Nd isotope...... compositions of uncontaminated primary magmas. This is because of the similar behaviour of Hf and Nd during fractional crystallisation and mantle melting, and the subsequent limited variation in Hf/Nd in mantle-derived magmas and in many crustal lithologies, resulting in linear contamination trends for Hf...

  15. Estimates of volume and magma input in crustal magmatic systems from zircon geochronology: the effect of modelling assumptions and system variables

    Science.gov (United States)

    Caricchi, Luca; Simpson, Guy; Schaltegger, Urs

    2016-04-01

    Magma fluxes in the Earth's crust play an important role in regulating the relationship between the frequency and magnitude of volcanic eruptions, the chemical evolution of magmatic systems and the distribution of geothermal energy and mineral resources on our planet. Therefore, quantifying magma productivity and the rate of magma transfer within the crust can provide valuable insights to characterise the long-term behaviour of volcanic systems and to unveil the link between the physical and chemical evolution of magmatic systems and their potential to generate resources. We performed thermal modelling to compute the temperature evolution of crustal magmatic intrusions with different final volumes assembled over a variety of timescales (i.e., at different magma fluxes). Using these results, we calculated synthetic populations of zircon ages assuming the number of zircons crystallising in a given time period is directly proportional to the volume of magma at temperature within the zircon crystallisation range. The statistical analysis of the calculated populations of zircon ages shows that the mode, median and standard deviation of the populations varies coherently as function of the rate of magma injection and final volume of the crustal intrusions. Therefore, the statistical properties of the population of zircon ages can add useful constraints to quantify the rate of magma injection and the final volume of magmatic intrusions. Here, we explore the effect of different ranges of zircon saturation temperature, intrusion geometry, and wall rock temperature on the calculated distributions of zircon ages. Additionally, we determine the effect of undersampling on the variability of mode, median and standards deviation of calculated populations of zircon ages to estimate the minimum number of zircon analyses necessary to obtain meaningful estimates of magma flux and final intrusion volume.

  16. Estimates of volume and magma input in crustal magmatic systems from zircon geochronology: the effect of modelling assumptions and system variables

    Directory of Open Access Journals (Sweden)

    Luca eCaricchi

    2016-04-01

    Full Text Available Magma fluxes in the Earth’s crust play an important role in regulating the relationship between the frequency and magnitude of volcanic eruptions, the chemical evolution of magmatic systems and the distribution of geothermal energy and mineral resources on our planet. Therefore, quantifying magma productivity and the rate of magma transfer within the crust can provide valuable insights to characterise the long-term behaviour of volcanic systems and to unveil the link between the physical and chemical evolution of magmatic systems and their potential to generate resources. We performed thermal modelling to compute the temperature evolution of crustal magmatic intrusions with different final volumes assembled over a variety of timescales (i.e., at different magma fluxes. Using these results, we calculated synthetic populations of zircon ages assuming the number of zircons crystallising in a given time period is directly proportional to the volume of magma at temperature within the zircon crystallisation range. The statistical analysis of the calculated populations of zircon ages shows that the mode, median and standard deviation of the populations varies coherently as function of the rate of magma injection and final volume of the crustal intrusions. Therefore, the statistical properties of the population of zircon ages can add useful constraints to quantify the rate of magma injection and the final volume of magmatic intrusions.Here, we explore the effect of different ranges of zircon saturation temperature, intrusion geometry, and wall rock temperature on the calculated distributions of zircon ages. Additionally, we determine the effect of undersampling on the variability of mode, median and standards deviation of calculated populations of zircon ages to estimate the minimum number of zircon analyses necessary to obtain meaningful estimates of magma flux and final intrusion volume.

  17. Utilization of prostate cancer screening according to dietary patterns and other demographic variables. The adventist health study-2.

    Science.gov (United States)

    Ibrayev, Yermek; Oda, Keiji; Fraser, Gary E; Knutsen, Synnove F

    2013-01-01

    Prostate-specific antigen test and digital rectal examination are considered important screening methods for early detection of prostate cancer. However, the utilization of prostate cancer screening varies widely and there is limited knowledge of the predictors of utilization. Self-reported prostate cancer screening utilization within the last 2 years was investigated among 11,162 black and non-black North American Seventh-day Adventist men, aged 50-75 years, with different dietary patterns and lifestyle characteristics. Blacks were more likely to screen for prostate cancer than non-blacks (Odds Ratio (OR)=1.38 (95% confidence interval (CI): 1.20-1.57). Those with a vegetarian diet, especially vegans, were less likely to follow screening guidelines, particularly among non-Blacks: vegans (OR=0.47, 0.39-0.58), lacto-ovo-vegetarians (OR=0.75, 0.66-0.86), and pesco-vegetarians (OR=0.74, 0.60-0.91) compared to non-vegetarians after adjusting for age, BMI, marital status, education, income, and family history of cancer. Trends for dietary patterns remained unchanged after stratification on age, family history of cancer, education, personal income, marital status, and BMI. Among black men, diet patterns showed no significant associations with utilization of prostate cancer screening, although vegans tended to underutilize screening compared to non-vegetarians (OR=0.70, 0.44-1.10). Vegetarians, especially non-black vegans, are less likely to follow recommended prostate cancer screening guidelines. The effect of diet was attenuated, and not statistically significant, among black men. Since only about 60% of US men follow prostate cancer screening guidelines, it is important to study reasons for non-compliance in order to increase utilization of preventive measures against prostate cancer.

  18. Determination of the Optimal Training Principle and Input Variables in Artificial Neural Network Model for the Biweekly Chlorophyll-a Prediction: A Case Study of the Yuqiao Reservoir, China

    Science.gov (United States)

    Liu, Yu; Xi, Du-Gang; Li, Zhao-Liang

    2015-01-01

    Predicting the levels of chlorophyll-a (Chl-a) is a vital component of water quality management, which ensures that urban drinking water is safe from harmful algal blooms. This study developed a model to predict Chl-a levels in the Yuqiao Reservoir (Tianjin, China) biweekly using water quality and meteorological data from 1999-2012. First, six artificial neural networks (ANNs) and two non-ANN methods (principal component analysis and the support vector regression model) were compared to determine the appropriate training principle. Subsequently, three predictors with different input variables were developed to examine the feasibility of incorporating meteorological factors into Chl-a prediction, which usually only uses water quality data. Finally, a sensitivity analysis was performed to examine how the Chl-a predictor reacts to changes in input variables. The results were as follows: first, ANN is a powerful predictive alternative to the traditional modeling techniques used for Chl-a prediction. The back program (BP) model yields slightly better results than all other ANNs, with the normalized mean square error (NMSE), the correlation coefficient (Corr), and the Nash-Sutcliffe coefficient of efficiency (NSE) at 0.003 mg/l, 0.880 and 0.754, respectively, in the testing period. Second, the incorporation of meteorological data greatly improved Chl-a prediction compared to models solely using water quality factors or meteorological data; the correlation coefficient increased from 0.574-0.686 to 0.880 when meteorological data were included. Finally, the Chl-a predictor is more sensitive to air pressure and pH compared to other water quality and meteorological variables. PMID:25768650

  19. A TCL/TK Widget for Display of MEDM Screens

    CERN Document Server

    Soliday, Robert

    2005-01-01

    A new Tcl/Tk widget has been created to display MEDM screens inside a Tcl/Tk application. Tcl/Tk parses the MEDM input files and the appropriate widgets are created and linked to the associated process variables. One advantage of this approach is that an X-Windows emulator is not required to view and manipulate the MEDM screen under a Windows operating system. Another benefit is that the MEDM screen can now be tightly integrated into a scripting language to attach higher-level logic to various process variable manipulations. Further details and examples of the new widget will be discussed.

  20. A TCL/TK widget for display of MEDM screens.

    Energy Technology Data Exchange (ETDEWEB)

    Soliday, R.; APS Operations Division

    2005-01-01

    A new Tcl/Tk widget has been created to display MEDM screens inside a Tcl/Tk application. Tcl/Tk parses the MEDM input files and the appropriate widgets are created and linked to the associated process variables. One advantage of this approach is that an X-Windows emulator is not required to view and manipulate the MEDM screen under a Windows operating system. Another benefit is that the MEDM screen can now be tightly integrated into a scripting language to attach higher-level logic to various process variable manipulations. Further details and examples of the new widget will be discussed.

  1. Utility of overnight pulse oximetry and heart rate variability analysis to screen for sleep-disordered breathing in chronic heart failure.

    Science.gov (United States)

    Ward, Neil R; Cowie, Martin R; Rosen, Stuart D; Roldao, Vitor; De Villa, Manuel; McDonagh, Theresa A; Simonds, Anita; Morrell, Mary J

    2012-11-01

    Sleep-disordered breathing (SDB) is under diagnosed in chronic heart failure (CHF). Screening with simple monitors may increase detection of SDB in a cardiology setting. This study aimed to evaluate the accuracy of heart rate variability analysis and overnight pulse oximetry for diagnosis of SDB in patients with CHF. 180 patients with CHF underwent simultaneous polysomnography, ambulatory electrocardiography and wrist-worn overnight pulse oximetry. SDB was defined as an apnoea-hypopnoea index ≥15/h. To identify SDB from the screening tests, the per cent very low frequency increment (%VLFI) component of heart rate variability was measured with a pre-specified cutoff ≥2.23%, and the 3% oxygen desaturation index was measured with a pre-specified cutoff >7.5 desaturations/h. 173 patients with CHF had adequate sleep study data; SDB occurred in 77 (45%) patients. Heart rate variability was measurable in 78 (45%) patients with area under the %VLFI receiver operating characteristic curve of 0.50. At the ≥2.23% cutoff, %VLFI sensitivity was 58% and specificity was 48%. The 3% oxygen desaturation index was measurable in 171 (99%) patients with area under the curve of 0.92. At the pre-specified cutoff of >7.5 desaturations/h, the 3% oxygen desaturation index had a sensitivity of 97%, specificity of 32%, negative likelihood ratio of 0.08 and positive likelihood ratio of 1.42. Diagnostic accuracy was increased using a cutoff of 12.5 desaturations/h, with sensitivity of 93% and specificity of 73%. The high sensitivity and low negative likelihood ratio of the 3% oxygen desaturation index indicates that pulse oximetry would be of use as a simple screening test to rule out SDB in patients with CHF in a cardiology setting. The %VLFI component of heart rate variability is not suitable for detection of SDB in CHF.

  2. Important Variables When Screening for Students at Suicidal Risk: Findings from the French Cohort of the SEYLE Study

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Kahn

    2015-09-01

    Full Text Available Due to early detection of mental ill-health being an important suicide preventive strategy, the multi-centre EU funded “Saving and Empowering Young Lives in Europe” (SEYLE study compared three school-based mental health promotion programs to a control group. In France, 1007 students with a mean age of 15.2 years were recruited from 20 randomly assigned schools. This paper explores the French results of the SEYLE’s two-stage screening program (ProfScreen and of the cross-program suicidal emergency procedure. Two-hundred-thirty-five ProfScreen students were screened using 13 psychopathological and risk behaviour scales. Students considered at risk because of a positive finding on one or more scales were offered a clinical interview and, if necessary, referred for treatment. A procedure for suicidal students (emergency cases was set up to detect emergencies in the whole cohort (n = 1007. Emergency cases were offered the same clinical interview as the ProfScreen students. The interviewers documented their reasons for referrals in a short report. 16,2% of the ProfScreen students (38/235 were referred to treatment and 2,7% of the emergency cases (27/1007 were also referred to treatment due to high suicidal risk. Frequent symptoms in those students referred for evaluation were depression, alcohol misuse, non-suicidal self-injuries (NSSI, and suicidal behaviours. According to the multivariate regression analysis of ProfScreen, the results show that the best predictors for treatment referral were NSSI (OR 2.85, alcohol misuse (OR 2.80, and depressive symptoms (OR 1.13. Analysis of the proportion for each scale of students referred to treatment showed that poor social relationships (60%, anxiety (50%, and suicidal behaviours (50% generated the highest rate of referrals. Qualitative analysis of clinician’s motivations to refer a student to mental health services revealed that depressive symptoms (51%, anxiety (38%, suicidal behaviours (40%, and

  3. Research on variable input washout algorithm for stewart platform vehicle simulator%六自由度平台车辆运动模拟器变输入洗出算法

    Institute of Scientific and Technical Information of China (English)

    罗竹辉; 魏燕定; 周晓军; 魏春雨

    2013-01-01

    For the purpose of enhancing the fidelity of Stewart platform vehicle simulator simulating dynamic motions of an actual vehicle, a variable input washout algorithm was proposed in combination with classic washout algorithm. Input signal of classic washout algorithm was differentiated and transformed based on the workspace of the simulator. High amplitude input signal was scaled to restrict the workspace of the simulator within its kinematic limitation. Low amplitude input signal was transformed by multiplying a time-varying proportionality coefficient. The time-varying proportionality coefficient was obtained using fuzzy adaptive algorithm. The inputs,output and rules of the fuzzy controller were set by the relationship between the human perception in the simulator and human perception in the vehicle and the input signal of the classic washout algorithm. The signal was taken as an example to simulate the perception about single degree of vehicle longitudinal motions, which was generated by real time dynamic software of the simulator. It shows that with the presented algorithm the simulator can not exceed the bound of the platform, and at the same time it can exploit the workspace of simulator efficiently and improve the fidelity of Stewart platform vehicle simulator simulating dynamic motions of an actual vehicle.%为提高六自由度平台车辆模拟器模拟真实车辆运动感觉的逼真度,结合经典洗出算法提出一种变输入洗出算法.根据模拟器运动空间,对经典洗出算法的输入信号按幅值大小进行划分、变换处理.高幅值输入信号采用缩放处理,以防止超出平台运动空间;低幅值输入信号乘上一个时变比例系数,时变比例系数的确定采用模糊自适应算法,根据人体在运动模拟器上的运动感觉、人体在车辆上的运动感觉以及输入信号的情况,选定模糊控制器的输入、输出和模糊控制规则.以车辆纵向加速度的模拟为例进行仿真,仿真

  4. QUESTIONNAIRES IN THE SCREENING FOR Schistosoma mansoni INFECTION: A STUDY OF SOCIO DEMOGRAPHIC AND WATER CONTACT VARIABLES IN FOUR COMMUNITIES IN BRAZIL

    Directory of Open Access Journals (Sweden)

    Lima e Costa Maria Fernanda F.

    1998-01-01

    Full Text Available The use of questionnaires has been recommended for identifying, at a lower cost, individuals at risk for schistosomiasis. In this study, validity of information obtained by questionnaire in the screening for Schistosoma mansoni infection was assessed in four communities in the State of Minas Gerais, Brazil. Explanatory variables were water contact activities, sociodemographic characteristics and previous treatment for schistosomiasis. From 677, 1474, 766 and 3290 individuals eligible for stool examination in the communities, 89 to 97% participated in the study. The estimated probability of individuals to be infected, if they have all characteristics identified as independently associated with S.mansoni infection, varied from 15% in Canabrava, to 42% in Belo Horizonte, 48% in Comercinho and 80% in São José do Acácio. Our results do not support the hypothesis that a same questionnaire on risk factors could be used in screening for S.mansoni infection in different communities.

  5. Anthropometric variables accurately predict dual energy x-ray absorptiometric-derived body composition and can be used to screen for diabetes.

    Directory of Open Access Journals (Sweden)

    Reza Yavari

    Full Text Available The current world-wide epidemic of obesity has stimulated interest in developing simple screening methods to identify individuals with undiagnosed diabetes mellitus type 2 (DM2 or metabolic syndrome (MS. Prior work utilizing body composition obtained by sophisticated technology has shown that the ratio of abdominal fat to total fat is a good predictor for DM2 or MS. The goals of this study were to determine how well simple anthropometric variables predict the fat mass distribution as determined by dual energy x-ray absorptometry (DXA, and whether these are useful to screen for DM2 or MS within a population. To accomplish this, the body composition of 341 females spanning a wide range of body mass indices and with a 23% prevalence of DM2 and MS was determined using DXA. Stepwise linear regression models incorporating age, weight, height, waistline, and hipline predicted DXA body composition (i.e., fat mass, trunk fat, fat free mass, and total mass with good accuracy. Using body composition as independent variables, nominal logistic regression was then performed to estimate the probability of DM2. The results show good discrimination with the receiver operating characteristic (ROC having an area under the curve (AUC of 0.78. The anthropometrically-derived body composition equations derived from the full DXA study group were then applied to a group of 1153 female patients selected from a general endocrinology practice. Similar to the smaller study group, the ROC from logistical regression using body composition had an AUC of 0.81 for the detection of DM2. These results are superior to screening based on questionnaires and compare favorably with published data derived from invasive testing, e.g., hemoglobin A1c. This anthropometric approach offers promise for the development of simple, inexpensive, non-invasive screening to identify individuals with metabolic dysfunction within large populations.

  6. The intra-hour variable quasar J1819$+$3845: 13-year evolution, jet polarization structure and interstellar scattering screen properties

    CERN Document Server

    de Bruyn, A G

    2014-01-01

    We examine the long-term evolution of the intra-hour variable quasar, J1819+3845, whose variations have been attributed to interstellar scintillation by extremely local turbulent plasma, located only 1-3pc from Earth. The variations in this source ceased some time between June 2006 and February 2007. The evolution of the source spectrum and the long-term lightcurve, and the persistent compactness of the source VLBI structure indicates that the cessation of rapid variability was associated with the passage of the scattering material out of the line of sight to the quasar. We present an analysis of the linear polarization variations and their relation to total intensity variations. The proper motion of polarized features in the quasar jet is found to be subluminal. Systematic time delays between Stokes I, Q and U, in combination with the structure of the source obtained from 8.4GHz VLBI data, confirm the estimate of the screen distance: 1-2pc, making the screen one of the nearest objects to the Solar System. We...

  7. Nitrogen loss from high N-input vegetable fields: a) Direct N2O emissions b) Spatiotemporal variability of N species (N2O, NH4+, NO3-) in soils

    Science.gov (United States)

    Palmer, I.; Pfab, H.; Ruser, R.; Fiedler, S.

    2009-04-01

    Nitrous oxide (N2O) is a greenhouse gas contributing to stratospheric ozone depletion. Soils are considered to be the major (70%) source for atmospheric N2O. Agriculture in general accounts for about 85% of the anthropogenic N2O emissions. Whereas 80% of these, are emitted from ag-riculturally used soils. Such estimations of N2O fluxes are associated with a high degree of uncertainties. Uncertainty of source strength estimates mainly results from local scale variability of known and unknown sources. It is not known how much uncertainty is due to unmeasured sources. For example, considerations of N2O fluxes from soils used for intensive vegetable production within inventories are still missing. We speculate that these types of arable soils act as ‚hot spots' for N2O. Given conditions (1) high N-input due to fertilization in concert with (2) easily mineralizable harvest residues should pro-mote disproportional high reaction rates in N-cycling and enhance N2O production as a by-product of nitrification and denitrification. Our investigation focused on the influence of: (1) N-input level (Ammonium Sulfate Nitrate (ASN)) below and above common N doses used for "good agricultural practice". (2) Application of modified fertilizers including nitrification inhibitor DMPP (Dimethylpyrazolphosphate, ENTEC®) and depot fertilization (pseudo-CULTAN) in comparison to non-fertilized control and common ASN application. (3) Effects of plant residues on N-cycling and (4) the deduction of mitigation strategies to reduce the potential N-loss from theses sites. The study was carried out during summer and autumn 2008 on a field cropped with cauliflower, located at the "Heidfeldhof" (South-West Germany; MAT 10.5°C, MAP 660 mm). Three different N-species (N2O; within gaseous soil phase, ammonium (NH4+) and nitrate (NO3-) extracted from bulk soil) were measured weekly in three different soil depths (0-25 cm; 25-50 cm and 50-75 cm) in a fully randomized field design. At same depths water

  8. Implementation of a Model Output Statistics based on meteorological variable screening for short‐term wind power forecast

    DEFF Research Database (Denmark)

    Ranaboldo, Matteo; Giebel, Gregor; Codina, Bernat

    2013-01-01

    is evaluated in two wind farms, located in different topographical areas and with different NWP grid spacing. Because of the high seasonal variability of NWP forecasts, it was considered appropriate to implement monthly stratified MOS. In both wind farms, the first predictors were always wind speeds (at....... The proposed MOS performed well in both wind farms, and its forecasts compare positively with an actual operative model in use at Risø DTU and other MOS types, showing minimum BIAS and improving NWP power forecast of around 15% in terms of root mean square error. Further improvements could be obtained...

  9. Queuing model with variable input rates, mistake service and impatient customers%输入率可变且有差错服务及不耐烦顾客的排队模型分析

    Institute of Scientific and Technical Information of China (English)

    潘全如

    2012-01-01

    在系统顾客容量不变的情况下,顾客到达系统后是否进入系统接受服务对销售行业影响是巨大的.从排队长度对顾客输入率的影响着手,研究了输入率、服务正确率及不耐烦顾客强度均与队长有关的排队模型,得出了进入系统的顾客流是泊松过程.系统中的顾客数是生灭过程,同时求得了系统的队长平稳分布,因没有进入系统而导致系统损失的概率、因不耐烦而离去的顾客的均值、单位时间内系统服务错误率、因系统容量有限而无法加入队列的损失概率等多项指标,得出了并非输入率越高系统就盈利越多、并非系统服务正确率越低系统就赚得越少等结论.还得到了能使企业利润最大化的系统容量及服务速度,为销售行业提高自己的销售业绩提供了很有价值的参考.%The customers do not necessarily get into the system though arriving at it in the case of a fixed customer number, which influences sales industry enormously. Focusing on the influence of queue length on input rate, we build up a queuing model with variable input rates,mistake service and impatient customers, and draw the following conclusions; the customers get into the system in Poissonian flow; the number of customers in the system is a birth-death process. We obtained the stationary queue length distribution of the model, the loss probability for the customers not entering the system while arriving at the system, the mean of the customers who leaves the system due to impatience, the service error rate per unit time and the loss probability for the customers not joining the queue due to the limited capacity of the system and so on. This paper also justifies the falsehood of the following assumptions: the bigger the input rate is, the more profit business will get; the bigger the number of impatient customers is, the less profit business will make. We also obtaind the appropriate service speed and capacity a

  10. Clinical Variability in Cardiovascular Disease Risk Factor Screening and Management in Adolescent and Young Adult Women with Polycystic Ovary Syndrome.

    Science.gov (United States)

    Baer, Tamara E; Milliren, Carly E; Walls, Courtney; DiVasta, Amy D

    2015-10-01

    To review the clinical presentation, evaluation, and management of normal-weight (NW), overweight (OW), and obese (OB) adolescent and young adult women with polycystic ovary syndrome (PCOS) during a 2-year follow-up. Retrospective chart review. One hundred seventy-three adolescent and young adult women, aged 12-22 years, diagnosed with PCOS. Demographic, health data, and laboratory measures were abstracted from 3 clinic visits: baseline and 1- and 2-year follow-up. Subjects were classified as NW, OW, or OB. Longitudinal data were analyzed using repeated-measures analysis of variance. Body mass index, self-reported concerns, and lifestyle changes. Most patients (73%) were OW or OB. Family history of type 2 diabetes was greater in OW (38%) and OB (53%) patients compared with NW (22%) patients (P = .002). Acanthosis nigricans was identified in OW (62%) and OB (21%) patients but not in NW patients (0%; P change in body mass index percentile occurred. Evidence-based interventions and recommendations for screening tests are needed to address CVD risk in adolescents and young adults with PCOS. Copyright © 2015 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  11. Mutation screening of familial Mediterranean fever in the Azeri Turkish population: Genotype-phenotype correlation and the clinical profile variability

    Directory of Open Access Journals (Sweden)

    Gharesouran Jalal

    2014-01-01

    Full Text Available Familial Mediterranean fever is known as a most frequent hereditary autoin-Xammatory among the autoinflammatory syndromes characterized by fever, arthritis and serosal inflammation. Clinically, the foremost severe symptom of the disease is amyloidosis, which may cause to renal failure. MEFV renal failure consists of ten exons and conservative mutations clustered in exon ten (M694V, V726A, M680I, M694I and exon two (E148Q are considered more common mutations within this coding region and that they are detected with a distinct frequency changes in line with ethnicity. The aim of this study was to research the spectrum of mutations in Azeri Turkish population. We evaluated the molecular test results of 82 patients and their parents from eighty families identified as having FMF clinical symptoms referred to Molecular Genetics Laboratory of the Department of Medical Genetics. Patients were referred by their physicians for MEFV mutation detection. The most frequent mutations were M694V respectively followed by M680I (G/C, V726A, M694I and E148Q mutations. A phenotypic variability was also ascertained between patients with different mutations and it must be considered within the daily management of FMF patients.

  12. On the variability of near-surface screen temperature anomalies in the 20 March 2015 solar eclipse.

    Science.gov (United States)

    Clark, Matthew R

    2016-09-28

    Near-surface air temperature (NSAT) anomalies during the 20 March 2015 solar eclipse are investigated at 266 UK sites, using operational data. The high density of observing sites, together with the wide range of ambient meteorological conditions, provided an unprecedented opportunity for analysis of the spatial variability of NSAT anomalies under relatively uniform eclipse conditions. Anomalies ranged from -0.03°C to -4.23°C (median -1.02°C). The maximum (negative) anomaly lagged the maximum obscuration by 15 min on average. Cloud cover impacted strongly on NSAT anomalies, with larger anomalies in clear-sky situations (peclipse, the topographical influences on NSAT anomalies were apparently dominated by variations in residual nocturnal inversion strength, as suggested by significant correlations between post-sunrise temperature and NSAT anomaly at clear-sky sites (larger negative anomalies with lower post-sunrise temperatures). The largest NSAT anomaly occurred at a coastal site where flow transitioned from onshore to offshore during the eclipse, in a situation with large coastal temperature gradients associated with antecedent nocturnal cooling.This article is part of the themed issue 'Atmospheric effects of solar eclipses stimulated by the 2015 UK eclipse'.

  13. Screening, expression, and characterization of an anti-human oxidized low-density lipoprotein single-chain variable fragment.

    Science.gov (United States)

    Kumano-Kuramochi, Miyuki; Fujimura, Takashi; Komba, Shiro; Maeda-Yamamoto, Mari; Machida, Sachiko

    2016-09-01

    Increased levels of oxidized low-density lipoprotein (OxLDL) in the blood circulation are correlated with atherosclerosis. Monoclonal antibody-based detection systems have been reported for OxLDL. We identified novel single-chain variable fragments (scFvs) having affinity for human OxLDL and related ligands. We constructed an scFv library from nonimmunized human spleen mRNA. Two types (γ+κ and μ+λ) of scFv phage libraries were enriched by biopanning, and five scFv clones with affinity for OxLDL were identified. The γκ5 scFv, which showed the highest affinity for OxLDL, was cloned into pET-22b(+) and expressed in Escherichia coli BL21(DE3). γκ5, expressed as an inclusion body in BL21(DE3), was refolded and purified. The specificity and sensitivity of γκ5 were analyzed using enzyme-linked immunosorbent assays (ELISAs). The γκ5 scFv showed affinity for OxLDL and acetylated LDL. The sensitivity of γκ5 to low concentrations (1-2 μg/mL) of OxLDL was higher than that to AcLDL and LDL. Finally, we developed a sandwich ELISA using γκ5 and CTLD14 (a lectin-like OxLDL receptor-1 ligand recognition region), which allowed specific detection of OxLDL at a level below 0.1 μg/mL. Our results indicated that the γκ5 scFv was a promising molecule for the detection of modified LDL at very low concentrations.

  14. Variabilidade espacial de atributos químicos de um argissolo para aplicação de insumos à taxa variável em diferentes formas de relevo Spatial variability of chemical attributes in an alfisol for variable rates of inputs in different forms of relief

    Directory of Open Access Journals (Sweden)

    Diogo M. Barbieri

    2008-12-01

    Full Text Available A agricultura de precisão implica análise da variabilidade espacial de fatores de produção e a aplicação de insumos de forma localizada. Várias são as causas que condicionam a variabilidade espacial dos solos, sendo o relevo um dos fatores mais importantes. O presente estudo teve por objetivo analisar a variabilidade espacial dos atributos químicos do solo e a elaboração de mapas de necessidade de aplicação de insumos de forma localizada, em áreas com diferentes formas de relevo. Duas parcelas de 1 ha cada foram delimitadas em áreas com topografia côncava e convexa. Foram retiradas, em cada área, 242 amostras de solos em 121 pontos, nas profundidades de solo de 0,00-0,20 m e 0,20-0,40 m. Os resultados de análise química foram submetidos às análises da estatística descritiva, geoestatística e interpolação por krigagem. A área convexa apresentou maior variabilidade espacial do solo em relação a área côncava. A adoção da agricultura de precisão possibilitou economia de aproximadamente 25 kg ha-1 de P2O5 na área côncava.The precision agriculture implies an analysis of spatial variability of production factors and the inputs application of located form. There are several factors that cause spatial variability in soils; relief is one of the most important ones. The objective of this study was to analyze the spatial variability, the chemical attributes of the soil and the elaboration of maps necessity for input application of located form, in areas with different relief forms. Two parcels of one hectare each were delimited in areas with concave and convex shaped topography. A set of 242 samples were collected from each area at 121 points in depths of 0.00-0.20 m and 0.20-0.40 m. The data were submitted to the descriptive statistical analyses, geostatistics and interpolation for kriging. The convex area presented more spatial variability of the soil in relation the concave area. The adoption of precision agriculture

  15. Seasonal and interannual variability of sedimentation and organic matter distribution in the Buor-Khaya Gulf: the primary recipient of input from Lena River and coastal erosion in the southeast Laptev Sea

    Directory of Open Access Journals (Sweden)

    A. N. Charkin

    2011-09-01

    Full Text Available Climate warming is amplified in the land-sea system of the East Siberian Arctic, which also holds large pools of vulnerable carbon in permafrost. This coastal area is strongly influenced by sediment and carbon transport from both its large rivers and extensive erosion of Pleistocene permafrost along its coastline. This study is investigating the coastal fate of the sediment and organic carbon delivered to the Buor-Khaya Gulf, which is the first recipient of the overwhelming fluvial discharge from the Lena River and is additionally receiving large input from extensive erosion of the coastal ice-complex (permafrost a.k.a. Yedoma; loess soil with high organic carbon content. Both water column suspended particulate matter (SPM and surface sediments were sampled at about 250 oceanographic stations in the Gulf in this multi-year effort, including one winter campaign, and analyzed for the distribution and sorting of sediment size, organic carbon content, and stable carbon isotope signals. The composition of the surface sediment suggests an overwhelmingly terrestrial contribution from both river and coastal erosion. The objective of this paper is to improve our understanding of the seasonal (i.e., winter vs summer and interannual variability of these coastal sedimentation processes and the dynamics of organic carbon (OC distribution in both the water column SPM and the surface sediments of the Buor-Khaya Gulf.

    Based on data collected during several years in the period 2000–2008, two different sedimentation regimes were revealed for the Buor-Khaya Gulf, the relative importance of each at a given time depend on hydrometeorological conditions, the Lena River water discharge and sea-ice regime: Type 1 erosion-accumulation and Type 2 accumulation.

    The Type 1 erosion-accumulation sedimentation regime is typical (2000–2006 for the ice-free period of the year (here considered in detail for August 2005. Under such conditions terrigenous

  16. ColloInputGenerator

    DEFF Research Database (Denmark)

    2013-01-01

    This is a very simple program to help you put together input files for use in Gries' (2007) R-based collostruction analysis program. It basically puts together a text file with a frequency list of lexemes in the construction and inserts a column where you can add the corpus frequencies. It requires...... it as input for basic collexeme collostructional analysis (Stefanowitsch & Gries 2003) in Gries' (2007) program. ColloInputGenerator is, in its current state, based on programming commands introduced in Gries (2009). Projected updates: Generation of complete work-ready frequency lists....

  17. Nitrogen loss from high N-input vegetable fields - a) direct N2O emissions b) Spatiotemporal variability of N species (N2O, NH4+, NO3-) in soils

    Science.gov (United States)

    Pfab, H.; Ruser, R.; Palmer, I.; Fiedler, S.

    2009-04-01

    Nitrous oxide is a climate relevant trace gas. It contributes 7.9 % to the total anthropogenic greenhouse gas emission and it is also involved in stratospheric ozone depletion. Approximately 85 % of the anthropogenic N2O emissions result from agricultural activities, more than 50 % are produced during microbial N-turnover processes in soils. Especially soils with high N-input (N-fertilizer and high amount of N in plant residues) like vegetable cropped soils are assumed to cause high N2O losses. The aims of the study presented were (i) to quantify the N2O loss from a vegetable field (lettuce-cauliflower crop rotation), (ii) to calculate an emission factor for the study site in Southwest Germany and to compare this factor with the default value provided by the IPCC (2006) and (iii) to test the emission reduction potential (Ammonium Sulfate Nitrate fertilizer, ASN either by reduced N-fertilization) in comparison with common N doses used for good agricultural practice or by the use of a nitrification inhibitor (DMPP), a banded N-application (lettuce) or a depot fertilization measure (pseudo-CULTAN in order to suppress nitrification). N2O fluxes determined with the closed chamber method were highly variable in time with strongly increased flux rates after N-fertilization in combination with rainfall or irrigation measures and after the incorporation of cauliflower crop residues. Using the mean soil nitrate contents of the top soil of our investigated treatments (0-25 cm depth), we could explain approximately 60 % of the variability of the cumulative N2O losses during the vegetation period of lettuce and cauliflower. The cumulative N2O emissions ranged between 0,99 kg N2O-N ha-1 from the unfertilized control plots (vegetation period) and 6,81 kg N2O-N ha-1 from the plots with the highest N-dose. Based on the guidelines of the IPCC (2006), we calculated an emission factor around 0,9 % for the cropping season. This value is in good agreement with the default value of the

  18. Construction of an artificially randomized IgNAR phage display library: screening of variable regions that bind to hen egg white lysozyme.

    Science.gov (United States)

    Ohtani, Maki; Hikima, Jun-ichi; Jung, Tae Sung; Kondo, Hidehiro; Hirono, Ikuo; Aoki, Takashi

    2013-02-01

    To develop a multi-antigen-specific immunoglobulin new antigen receptor (IgNAR) variable (V) region phage display library, CDR3 in the V region of IgNAR from banded houndshark (Triakis scyllium) was artificially randomized, and clones specific for hen egg white lysozyme (HEL) were obtained by the biopanning method. The nucleotide sequence of CDR3 in the V region was randomly rearranged by PCR. Randomized CDR3-containing segments of the V region were ligated into T7 phage vector to construct a phage display library and resulted in a phage titer of 3.7 × 10(7) PFU/ml. Forty clones that contained randomized CDR3 inserts were sequenced and shown to have different nucleotide sequences. The HEL-specific clones were screened by biopanning using HEL-coated ELISA plates. After six rounds of screening, nine clones were identified as HEL-specific, eight of which showed a strong affinity to HEL in ELISA compared to a negative control (i.e., empty phage clone). The deduced amino acid sequences of CDR3 from the HEL-specific phage clones fell into four types (I-IV): type I contains a single cysteine residue and type II-IV contain two cysteine residues. These results indicated that the artificially randomized IgNAR library is useful for the rapid isolation of antigen-specific IgNAR V region without immunization of target antigen and showed that it is possible to isolate an antigen-specific IgNAR V region from this library.

  19. An Objective Screening Method for Major Depressive Disorder Using Logistic Regression Analysis of Heart Rate Variability Data Obtained in a Mental Task Paradigm

    Directory of Open Access Journals (Sweden)

    Guanghao Sun

    2016-11-01

    Full Text Available Background and Objectives: Heart rate variability (HRV has been intensively studied as a promising biological marker of major depressive disorder (MDD. Our previous study confirmed that autonomic activity and reactivity in depression revealed by HRV during rest and mental task (MT conditions can be used as diagnostic measures and in clinical evaluation. In this study, logistic regression analysis (LRA was utilized for the classification and prediction of MDD based on HRV data obtained in an MT paradigm.Methods: Power spectral analysis of HRV on R-R intervals before, during, and after an MT (random number generation was performed in 44 drug-naïve patients with MDD and 47 healthy control subjects at Department of Psychiatry in Shizuoka Saiseikai General Hospital. Logit scores of LRA determined by HRV indices and heart rates discriminated patients with MDD from healthy subjects. The high frequency (HF component of HRV and the ratio of the low frequency (LF component to the HF component (LF/HF correspond to parasympathetic and sympathovagal balance, respectively.Results: The LRA achieved a sensitivity and specificity of 80.0% and 79.0%, respectively, at an optimum cutoff logit score (0.28. Misclassifications occurred only when the logit score was close to the cutoff score. Logit scores also correlated significantly with subjective self-rating depression scale scores (p < 0.05.Conclusion: HRV indices recorded during a mental task may be an objective tool for screening patients with MDD in psychiatric practice. The proposed method appears promising for not only objective and rapid MDD screening, but also evaluation of its severity.

  20. Screening and identification of human ZnT8-specific single-chain variable fragment (scFv) from type 1 diabetes phage display library.

    Science.gov (United States)

    Wu, Qian; Wang, Xiaodong; Gu, Yong; Zhang, Xiao; Qin, Yao; Chen, Heng; Xu, Xinyu; Yang, Tao; Zhang, Mei

    2016-07-01

    Zinc transporter 8 (ZnT8) is a major autoantigen and a predictive marker in type 1 diabetes (T1D). To investigate ZnT8-specific antibodies, a phage display library from T1D was constructed and single-chain antibodies against ZnT8 were screened and identified. Human T1D single-chain variable fragment (scFv) phage display library consists of approximately 1×10(8) clones. After four rounds of bio-panning, seven unique clones were positive by phage ELISA. Among them, C27 and C22, which demonstrated the highest affinity to ZnT8, were expressed in Escherichia coli Top10F' and then purified by affinity chromatography. C27 and C22 specifically bound ZnT8 N/C fusion protein and ZnT8 C terminal dimer with one Arg325Trp mutation. The specificity to human islet cells of these scFvs were further confirmed by immunohistochemistry. In conclusion, we have successfully constructed a T1D phage display antibody library and identified two ZnT8-specific scFv clones, C27 and C22. These ZnT8-specific scFvs are potential agents in immunodiagnostic and immunotherapy of T1D.

  1. Harmonize input selection for sediment transport prediction

    Science.gov (United States)

    Afan, Haitham Abdulmohsin; Keshtegar, Behrooz; Mohtar, Wan Hanna Melini Wan; El-Shafie, Ahmed

    2017-09-01

    In this paper, three modeling approaches using a Neural Network (NN), Response Surface Method (RSM) and response surface method basis Global Harmony Search (GHS) are applied to predict the daily time series suspended sediment load. Generally, the input variables for forecasting the suspended sediment load are manually selected based on the maximum correlations of input variables in the modeling approaches based on NN and RSM. The RSM is improved to select the input variables by using the errors terms of training data based on the GHS, namely as response surface method and global harmony search (RSM-GHS) modeling method. The second-order polynomial function with cross terms is applied to calibrate the time series suspended sediment load with three, four and five input variables in the proposed RSM-GHS. The linear, square and cross corrections of twenty input variables of antecedent values of suspended sediment load and water discharge are investigated to achieve the best predictions of the RSM based on the GHS method. The performances of the NN, RSM and proposed RSM-GHS including both accuracy and simplicity are compared through several comparative predicted and error statistics. The results illustrated that the proposed RSM-GHS is as uncomplicated as the RSM but performed better, where fewer errors and better correlation was observed (R = 0.95, MAE = 18.09 (ton/day), RMSE = 25.16 (ton/day)) compared to the ANN (R = 0.91, MAE = 20.17 (ton/day), RMSE = 33.09 (ton/day)) and RSM (R = 0.91, MAE = 20.06 (ton/day), RMSE = 31.92 (ton/day)) for all types of input variables.

  2. Effect of correlated inputs on DO (dissolved oxygen) uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Brown, L.C.; Song, Q.

    1988-06-01

    Although uncertainty analysis has been discussed in recent water-quality-modeling literature, much of the work has assumed that all input variables and parameters are mutually independent. The objective of this paper is to evaluate the importance of correlation among the model inputs in the study of model-output uncertainty. The model used for demonstrating the influence of input-variable correlation is the Streeter-Phelps dissolved oxygen equation. The model forms the basis of many of the water-quality models currently in use and the relationships between model inputs and output-state variables are well understood.

  3. The effects of haptic input on biomechanical and neurophysiological parameters of walking: A scoping review.

    Science.gov (United States)

    Oates, Alison R; Hauck, Laura; Moraes, Renato; Sibley, Kathryn M

    2017-08-09

    Walking is an important component of daily life requiring sensorimotor integration to be successful. Adding haptic input via light touch or anchors has been shown to improve standing balance; however, the effect of adding haptic input on walking is not clear. This scoping review systematically summarizes the current evidence regarding the addition of haptic input on walking in adults. Following an established protocol, relevant studies were identified using indexed data bases (Medline, EMBASE, PsychINFO, Google Scholar) and hand searches of published review articles on related topics. 644 references were identified and screened by a minimum of two independent researchers before data was extracted from 17 studies. A modified TREND tool was used to assess quality of the references which showed that the majority of studies were of moderate or high quality. Results show that adding haptic input changes walking behaviour. In particular, there is an immediate reduction in variability of gait step parameters and whole body stability, as well as a decrease in lower limb muscle activity. The effect of added haptic input on reflex modulation may depend on the limb of interest (i.e., upper or lower limb). Many studies did not clearly describe the amount and/or direction of haptic input applied. This information is needed to replicate and/or advance their results. More investigations into the use and design of the haptic tools, the attentional demands of adding haptic input, and clarity on short-term effects are needed. In addition, more is research needed to determine whether adding haptic input has significant, lasting benefits that may translate to fall prevention efforts. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Inventions on GUI for Touch Sensitive Screens

    OpenAIRE

    Mishra, Umakant

    2014-01-01

    A touch sensitive screen displays the information on the screen and also receives the input by sensing a user's touch on the same screen. This mechanism facilitates system interaction directly through the screen without needing a mouse or keyboard. This method has the advantage to make the system compact by removing keyboard, mouse and similar interactive device. However there are certain difficulties to implement a touch screen interface. The display screens of portable devices are becoming ...

  5. Input or intimacy

    Directory of Open Access Journals (Sweden)

    Judit Navracsics

    2014-01-01

    Full Text Available According to the critical period hypothesis, the earlier the acquisition of a second language starts, the better. Owing to the plasticity of the brain, up until a certain age a second language can be acquired successfully according to this view. Early second language learners are commonly said to have an advantage over later ones especially in phonetic/phonological acquisition. Native-like pronunciation is said to be most likely to be achieved by young learners. However, there is evidence of accentfree speech in second languages learnt after puberty as well. Occasionally, on the other hand, a nonnative accent may appear even in early second (or third language acquisition. Cross-linguistic influences are natural in multilingual development, and we would expect the dominant language to have an impact on the weaker one(s. The dominant language is usually the one that provides the largest amount of input for the child. But is it always the amount that counts? Perhaps sometimes other factors, such as emotions, ome into play? In this paper, data obtained from an EnglishPersian-Hungarian trilingual pair of siblings (under age 4 and 3 respectively is analyzed, with a special focus on cross-linguistic influences at the phonetic/phonological levels. It will be shown that beyond the amount of input there are more important factors that trigger interference in multilingual development.

  6. Access to Research Inputs

    DEFF Research Database (Denmark)

    Czarnitzki, Dirk; Grimpe, Christoph; Pellens, Maikel

    The viability of modern open science norms and practices depend on public disclosure of new knowledge, methods, and materials. However, increasing industry funding of research can restrict the dissemination of results and materials. We show, through a survey sample of 837 German scientists in life...... sciences, natural sciences, engineering, and social sciences, that scientists who receive industry funding are twice as likely to deny requests for research inputs as those who do not. Receiving external funding in general does not affect denying others access. Scientists who receive external funding...... of any kind are, however, 50% more likely to be denied access to research materials by others, but this is not affected by being funded specifically by industry....

  7. Access to Research Inputs

    DEFF Research Database (Denmark)

    Czarnitzki, Dirk; Grimpe, Christoph; Pellens, Maikel

    2015-01-01

    The viability of modern open science norms and practices depends on public disclosure of new knowledge, methods, and materials. However, increasing industry funding of research can restrict the dissemination of results and materials. We show, through a survey sample of 837 German scientists in life...... sciences, natural sciences, engineering, and social sciences, that scientists who receive industry funding are twice as likely to deny requests for research inputs as those who do not. Receiving external funding in general does not affect denying others access. Scientists who receive external funding...... of any kind are, however, 50 % more likely to be denied access to research materials by others, but this is not affected by being funded specifically by industry...

  8. Seasonal and interannual variability of sedimentation and organic matter distribution in the Buor Khaya Gulf – the primary recipient of input from Lena River and coastal erosion in the SE Laptev Sea

    Directory of Open Access Journals (Sweden)

    A. N. Charkin

    2011-02-01

    Full Text Available Climate warming is amplified in the land-sea system of the East Siberian Arctic, which also holds large pools of vulnerable carbon in permafrost. This coastal area is strongly influenced by sediment and carbon transport from both its large rivers and extensive erosion of Pleistocene permafrost along its coastline. This study is investigating the coastal fate of the sediment and organic carbon delivered to the Buor-Khaya Gulf, which is the first recipient of the 16 overwhelming fluvial discharge from the Lena River and is additionally receiving large input from extensive erosion of the coastal ice-complex (permafrost a.k.a. Yedoma; loess soil with high organic carbon content. Both water column suspended particulate matter (SPM and surface sediments were sampled at about 250 oceanographic stations in the Gulf in this multiyear effort, including one winter campaign, and analyzed for the distribution and sorting of sediment size, organic carbon content, and stable carbon isotope signals. The composition of the surface sediment suggests an overwhelmingly terrestrial contribution from both river and coastal erosion.

    Based on data collected during several years in the period 2000–2008, two different sedimentation regimes were revealed for the Buor-Khaya Gulf, the relative importance of each at a given time depend on hydrometeorological conditions, the Lena River water discharge and sea-ice regime: Type 1 erosion-accumulation and Type 2 accumulation.

    The Type 1 erosion-accumulation sedimentation regime is typical (2000–2006 for the ice-free period of the year (here considered in detail for August 2005. Under such conditions terrigenous sources of suspended particulate matter (SPM and particulate organic carbon (POC stem predominantly from river discharge, thermal erosion of coastal ice-complex and remobilized bottom sediments. The Type 2 accumulation sedimentation regime develops under ice

  9. [Near-infrared spectra combining with CARS and SPA algorithms to screen the variables and samples for quantitatively determining the soluble solids content in strawberry].

    Science.gov (United States)

    Li, Jiang-bo; Guo, Zhi-ming; Huang, Wen-qian; Zhang, Bao-hua; Zhao, Chun-jiang

    2015-02-01

    In using spectroscopy to quantitatively or qualitatively analyze the quality of fruit, how to obtain a simple and effective correction model is very critical for the application and maintenance of the developed model. Strawberry as the research object, this research mainly focused on selecting the key variables and characteristic samples for quantitatively determining the soluble solids content. Competitive adaptive reweighted sampling (CARS) algorithm was firstly proposed to select the spectra variables. Then, Samples of correction set were selected by successive projections algorithm (SPA), and 98 characteristic samples were obtained. Next, based on the selected variables and characteristic samples, the second variable selection was performed by using SPA method. 25 key variables were obtained. In order to verify the performance of the proposed CARS algorithm, variable selection algorithms including Monte Carlo-uninformative variable elimination (MC-UVE) and SPA were used as the comparison algorithms. Results showed that CARS algorithm could eliminate uninformative variables and remove the collinearity information at the same time. Similarly, in order to assess the performance of the proposed SPA algorithm for selecting the characteristic samples, SPA algorithm was compared with classical Kennard-Stone algorithm Results showed that SPA algorithm could be used for selection of the characteristic samples in the calibration set. Finally, PLS and MLR model for quantitatively predicting the SSC (soluble solids content) in the strawberry were proposed based on the variables/samples subset (25/98), respectively. Results show that models built by using the 0.59% and 65.33% information of original variables and samples could obtain better performance than using the ones obtained by using all information of the original variables and samples. MLR model was the best with R(pre)2 = 0.9097, RMSEP=0.3484 and RPD = 3.3278.

  10. The Kepler Input Catalog

    Science.gov (United States)

    Latham, D. W.; Brown, T. M.; Monet, D. G.; Everett, M.; Esquerdo, G. A.; Hergenrother, C. W.

    2005-12-01

    The Kepler mission will monitor 170,000 planet-search targets during the first year, and 100,000 after that. The Kepler Input Catalog (KIC) will be used to select optimum targets for the search for habitable earth-like transiting planets. The KIC will include all known catalogued stars in an area of about 177 square degrees centered at RA 19:22:40 and Dec +44:30 (l=76.3 and b=+13.5). 2MASS photometry will be supplemented with new ground-based photometry obtained in the SDSS g, r, i, and z bands plus a custom filter centered on the Mg b lines, using KeplerCam on the 48-inch telescope at the Whipple Observatory on Mount Hopkins, Arizona. The photometry will be used to estimate stellar characteristics for all stars brighter than K 14.5 mag. The KIC will include effective temperature, surface gravity, metallicity, reddening, distance, and radius estimates for these stars. The CCD images are pipeline processed to produce instrumental magnitudes at PSI. The photometry is then archived and transformed to the SDSS system at HAO, where the astrophysical analysis of the stellar characteristics is carried out. The results are then merged with catalogued data at the USNOFS to produce the KIC. High dispersion spectroscopy with Hectochelle on the MMT will be used to supplement the information for many of the most interesting targets. The KIC will be released before launch for use by the astronomical community and will be available for queries over the internet. Support from the Kepler mission is gratefully acknowledged.

  11. Serial Input Output

    Energy Technology Data Exchange (ETDEWEB)

    Waite, Anthony; /SLAC

    2011-09-07

    Serial Input/Output (SIO) is designed to be a long term storage format of a sophistication somewhere between simple ASCII files and the techniques provided by inter alia Objectivity and Root. The former tend to be low density, information lossy (floating point numbers lose precision) and inflexible. The latter require abstract descriptions of the data with all that that implies in terms of extra complexity. The basic building blocks of SIO are streams, records and blocks. Streams provide the connections between the program and files. The user can define an arbitrary list of streams as required. A given stream must be opened for either reading or writing. SIO does not support read/write streams. If a stream is closed during the execution of a program, it can be reopened in either read or write mode to the same or a different file. Records represent a coherent grouping of data. Records consist of a collection of blocks (see next paragraph). The user can define a variety of records (headers, events, error logs, etc.) and request that any of them be written to any stream. When SIO reads a file, it first decodes the record name and if that record has been defined and unpacking has been requested for it, SIO proceeds to unpack the blocks. Blocks are user provided objects which do the real work of reading/writing the data. The user is responsible for writing the code for these blocks and for identifying these blocks to SIO at run time. To write a collection of blocks, the user must first connect them to a record. The record can then be written to a stream as described above. Note that the same block can be connected to many different records. When SIO reads a record, it scans through the blocks written and calls the corresponding block object (if it has been defined) to decode it. Undefined blocks are skipped. Each of these categories (streams, records and blocks) have some characteristics in common. Every stream, record and block has a name with the condition that each

  12. Expanding circadian input, output, and the clock through genomic screens

    OpenAIRE

    2011-01-01

    Many aspects of mammalian physiology display circadian--or once daily--rhythms, such as heart rate, blood pressure, activity levels, metabolism, and liver regeneration. These rhythms are regulated by an entrainable, self-sustaining, cell-autonomous mechanism found in nearly every cell of the body: the circadian clock. The circadian clock itself represents a regulatory network, composed of interlocking negative feedback loops, that in turn is influenced by two other types of regulatory network...

  13. The concise cognitive test for dementia screening: Reliability and effects of demographic variables as compared to the mini mental state examination

    Directory of Open Access Journals (Sweden)

    Srinivasan Srikanth

    2010-12-01

    Full Text Available Background: The Mini Mental State Examination (MMSE is widely used for dementia screening but has several shortcomings such as prominent ceiling effects, inadequate sensitivity to mild cognitive impairment, and uneven sampling of the major cognitive domains. Aims: In this study, we pilot a new dementia screening test - the Concise Cognitive Test (CONCOG - designed to overcome the above short comings and describe the reliability measures and age, education, and gender effects. The CONCOG has a total score of 30, and has subtests for orientation, naming, registration, free recall and recognition of four words, semantic verbal fluency and copying. Patients and Methods: Participants were screened to exclude those with any neurological or psychiatric disease, simultaneously administered the CONCOG, and a Hybrid Mini Mental State Examination (HMMSE adapted from Folstein′s MMSE and Ganguli′s Hindi Mental State Examination. Results: The study sample had 204 subjects over the age of 60 years with a mean of 73 years and education level of 8 (4.5 years. Internal consistency for the CONCOG (Cronbach′s alpha was 0.74, inter-rater reliability (Kendall′s tau-b was 0.9, and the one-month test-retest reliability (Kendall′s tau-b was 0.7. Age and education level, but not gender, significantly influenced performance on both scales. Although the influence of age on the two scales was to a similar degree, the HMMSE was more affected by education than the CONCOG. Of 204 subjects, only 12 (5.7% subjects obtained the maximum score on the CONCOG compared with 30 (14.1% subjects on the HMMSE. The CONCOG took less than 10 minutes to complete in this sample. Age and education stratified norms are presented for the CONCOG. Conclusions: The CONCOG is a reliable cognitive screening measure. It has negligible ceiling effects, is less influenced by education compared with the HMMSE, and offers subscale scores for the major cognitive domains.

  14. Vision Screening

    Science.gov (United States)

    ... of Prematurity Strabismus Stye (defined) Vision Screening Vision Screening Recommendations Loading... Most Common Searches Adult Strabismus Amblyopia Cataract Conjunctivitis Corneal Abrasions Dilating Eye ...

  15. Should prior FIT results be incorporated as an additional variable to estimate risk of colorectal neoplasia? A prospective study of 5,813 screening colonoscopies.

    Directory of Open Access Journals (Sweden)

    Martin C S Wong

    Full Text Available Recent studies showed that previous negative results from faecal immunochemical tests (FITs for colorectal cancer (CRC screening was associated with lower risk of advanced neoplasia (AN. We evaluated whether prior FIT results should be included to estimate the risk of AN in 2008-2012.A community-based screening practice recruited 5,813 asymptomatic residents aged 50 to 70 years in Hong Kong for CRC screening. We included study participants who had (1. positive FIT with subsequent colonoscopy workup (FIT+ group; n = 356; (2. negative FIT in three consecutive years and received a colonoscopy (FIT- group; n = 857; (3. received colonoscopy without FIT (colonoscopy group; n = 473; and (4. received both colonoscopy and FIT at the same time (combined group; n = 4,127. One binary logistic regression model evaluated whether prior FIT results were associated with colonoscopy findings of AN.The proportion of participants having AN/CRC was 18.0% (FIT+, 5.5% (FIT-, 8.0% (colonoscopy group, and 4.3% (combined group, respectively. When compared with the colonoscopy group, those in the FIT- group were not significantly more or less likely to have AN/CRC (AOR = 0.77, 95% C.I. = 0.51 to 1.18, p = 0.230. Having one (AOR = 0.73, 95% C.I. 0.48-1.12, p = 0.151 or three consecutive negative FIT result (AOR = 0.98, 95% C.I. 0.60-1.62, p = 0.944 were not associated with lower risks of AN/CRC. Subjects in the FIT+ group was 3.32-fold (95% C.I. 2.07 to 5.32, p < 0.001 more likely to have AN/CRC.These findings indicated that subjects with negative FIT findings could be risk stratified similarly as those who had not previously received FIT.

  16. Linear Regression in High Dimension and/or for Correlated Inputs

    Science.gov (United States)

    Jacques, J.; Fraix-Burnet, D.

    2014-12-01

    Ordinary least square is the common way to estimate linear regression models. When inputs are correlated or when they are too numerous, regression methods using derived inputs directions or shrinkage methods can be efficient alternatives. Methods using derived inputs directions build new uncorrelated variables as linear combination of the initial inputs, whereas shrinkage methods introduce regularization and variable selection by penalizing the usual least square criterion. Both kinds of methods are presented and illustrated thanks to the R software on an astronomical dataset.

  17. Data-quality issues and alternative variable-screening methods in a questionnaire-based study on subclinical Salmonella enterica infection in Danish pig herds

    DEFF Research Database (Denmark)

    Stege, H.; Christensen, J.; Nielsen, J.P.

    2001-01-01

    Our aim was to determine risk factors for subclinical Salmonella enterica infection in Danish finishing-pig herds. In this paper, the evaluation, combining and initial reduction of variables is presented, along with assessment of the hypothesis in the preliminary statistical testing. The first...... seroprevalence. This resulted in a hybrid case-"control" design of the study and therefore, five different methods of categorising the data were used to ensure that variables were not wrongfully excluded as a result of using an improper design. Our questionnaire focused on management, infection......-limiting precautions and feed and feeding procedures. To establish the prevalence of S. enterica infection within herds at the time of the visit, 50 blood samples from each herd were collected and serologically examined. The reliability of each variable from the questionnaire was assessed and it was decided which...

  18. Input in Second Language Acquisition.

    Science.gov (United States)

    Gass, Susan M., Ed.; Madden, Carolyn G., Ed.

    This collection of conference papers includes: "When Does Teacher Talk Work as Input?"; "Cultural Input in Second Language Learning"; "Skilled Variation in a Kindergarten Teacher's Use of Foreigner Talk"; "Teacher-Pupil Interaction in Second Language Development"; "Foreigner Talk in the University…

  19. Inputs for L2 Acquisition.

    Science.gov (United States)

    Saleemi, Anjum P.

    1989-01-01

    Major approaches of describing or examining linguistic data from a potential target language (input) are analyzed for adequacy in addressing the concerns of second language learning theory. Suggestions are made for making the best of these varied concepts of input and for reformulation of a unified concept. (MSE)

  20. Input and Second Language Acquisition

    Institute of Scientific and Technical Information of China (English)

    周笑盈

    2011-01-01

    The behaviorist, the mentalist and the interactionist have different emphases on the role input in Second Language Acquisition. In order to protrude the importance of second language teaching, it is indispensible to discuss the characteristics of input and to explore its effects.

  1. The intra-hour variable quasar J1819+3845: 13-year evolution, jet polarization structure, and interstellar scattering screen properties

    NARCIS (Netherlands)

    de Bruyn, A. G.; Macquart, J.-P.

    2015-01-01

    We examine the long-term evolution of the intra-hour variable quasar, J1819+3845, whose variations have been attributed to interstellar scintillation by extremely local turbulent plasma, located only 1-3 pc from Earth. The variations in this source ceased some time in the period between June 2006 an

  2. A quality by design (QbD case study on enteric-coated pellets: Screening of critical variables and establishment of design space at laboratory scale

    Directory of Open Access Journals (Sweden)

    Shuling Kan

    2014-10-01

    Full Text Available The study aims to prepare naproxen enteric-coated pellets (NAP-ECPs by fluid-bed coating using QbD principle. Risk assessment was firstly performed by using failure mode and effect analysis (FMEA methodology. A Plackett–Burman design was then used for assessment of the most important variables affecting enteric-coated pellets characteristics. A Box–Behnken design was subsequently used for investigating the main, interactive, and quadratic effects of these variables on the response. By FMEA we discovered that eight factors should be considered to be high/important risk variables as compared with others. The responses of acid resistance and cumulative drug release were taken as critical quality attributes (CQAs. Pareto ranking analyses indicated that the coating weight gain (X7, triethyl citrate percentage (X1 and glycerol monostearate percentage (X2 were the most significant factors affecting the selected responses out of the eight high-risk variables. Optimization with response surface method (RSM further fully clarified the relationship between X7, X1, X2 and CQAs, and design space was established based on the constraints set on the responses. Due to the extreme coincidence of the predicted value generated by model with the observed value, the accuracy and robustness of the model were confirmed. It could be concluded that a promising NAP-ECPs was successfully designed using QbD approach in a laboratory scale.

  3. Toxicity screening of soils from different mine areas—A contribution to track the sensitivity and variability of Arthrobacter globiformis assay

    Energy Technology Data Exchange (ETDEWEB)

    Marques, Catarina R., E-mail: crmarques@ua.pt [Departamento de Biologia and CESAM (Centro de Estudos do Ambiente e do Mar), Universidade de Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro (Portugal); Caetano, Ana L. [Departamento de Biologia and CESAM (Centro de Estudos do Ambiente e do Mar), Universidade de Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro (Portugal); Haller, Andreas [ECT Oekotoxikologie GmbH, Böttgerstraße 2–14, D-65439 Flörsheim a. M. (Germany); Gonçalves, Fernando [Departamento de Biologia and CESAM (Centro de Estudos do Ambiente e do Mar), Universidade de Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro (Portugal); Pereira, Ruth [Faculdade de Ciências da Universidade do Porto, Rua do Campo Alegre, s/n, 4169-007 Porto (Portugal); Interdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), Universidade do Porto, Rua dos Bragas 289, P 4050-123 Porto (Portugal); Römbke, Jörg [ECT Oekotoxikologie GmbH, Böttgerstraße 2–14, D-65439 Flörsheim a. M. (Germany)

    2014-06-01

    Highlights: • The assay gave rapid and feasible discrimination of toxic soils to A. globiformis. • Sensitive and low variability response to soils from different regions. • Soil properties may interfere with metal toxicity and fluorescence measurements. • Proposal of a toxicity threshold for the contact assay regarding soils. • A. globiformis assay should be included in the Tier I of risk assessment frameworks. - Abstract: This study used the Arthrobacter globiformis solid-contact test for assessing the quality of soils collected in areas subjected to past and present mine activities in Europe (uranium mine, Portugal) and North Africa (phosphogypsum pile, Tunisia; iron mine, Morocco). As to discriminate the influence of soils natural variability from the effect of contaminants, toxicity thresholds were derived for this test, based on the dataset of each study area. Furthermore, the test sensitivity and variability was also evaluated. As a result, soils that inhibited A. globiformis dehydrogenase activity above 45% or 50% relatively to the control, were considered to be toxic. Despite the soil metal content determined, the properties of soils seemed to influence dehydrogenase activity. Overall, the contact test provided a coherent outcome comparing to other more time-consuming and effort-demanding ecotoxicological assays. Our results strengthened the feasibility and ecological relevance of this assay, which variability was quite reduced hence suggesting its potential integration within the test battery of tier 1 of soil risk assessment schemes.

  4. Does Input Quality Drive Measured Differences in Firm Productivity?

    DEFF Research Database (Denmark)

    Fox, Jeremy T.; Smeets, Valerie Anne Rolande

    2011-01-01

    One explanation for productivity dispersion is that the quality of inputs differs across firms. We add labor market history variables such as experience and firm and industry tenure, as well as general human capital measures such as schooling and sex. Adding these variables decreases the ratio of...

  5. Input saturation in nonlinear multivariable processes resolved by nonlinear decoupling

    Directory of Open Access Journals (Sweden)

    Jens G. Balchen

    1995-04-01

    Full Text Available A new method is presented for the resolution of the problem of input saturation in nonlinear multivariable process control by means of elementary nonlinear decoupling (END. Input saturation can have serious consequences particularly in multivariable control because it may lead to very undesirable system behaviour and quite often system instability. Many authors have searched for systematic techniques for designing multivariable control systems in which saturation may occur in any of the control variables (inputs, manipulated variables. No generally accepted method seems to have been presented so far which gives a solution in closed form. The method of elementary nonlinear decoupling (END can be applied directly to the case of saturation control variables by deriving as many control strategies as there are combinations of saturating control variables. The method is demonstrated by the multivariable control of a simulated Fluidized Catalytic Cracker (FCC with very convincing results.

  6. Toxicity screening of soils from different mine areas--a contribution to track the sensitivity and variability of Arthrobacter globiformis assay.

    Science.gov (United States)

    Marques, Catarina R; Caetano, Ana L; Haller, Andreas; Gonçalves, Fernando; Pereira, Ruth; Römbke, Jörg

    2014-06-15

    This study used the Arthrobacter globiformis solid-contact test for assessing the quality of soils collected in areas subjected to past and present mine activities in Europe (uranium mine, Portugal) and North Africa (phosphogypsum pile, Tunisia; iron mine, Morocco). As to discriminate the influence of soils natural variability from the effect of contaminants, toxicity thresholds were derived for this test, based on the dataset of each study area. Furthermore, the test sensitivity and variability was also evaluated. As a result, soils that inhibited A. globiformis dehydrogenase activity above 45% or 50% relatively to the control, were considered to be toxic. Despite the soil metal content determined, the properties of soils seemed to influence dehydrogenase activity. Overall, the contact test provided a coherent outcome comparing to other more time-consuming and effort-demanding ecotoxicological assays. Our results strengthened the feasibility and ecological relevance of this assay, which variability was quite reduced hence suggesting its potential integration within the test battery of tier 1 of soil risk assessment schemes. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Input management of production systems.

    Science.gov (United States)

    Odum, E P

    1989-01-13

    Nonpoint sources of pollution, which are largely responsible for stressing regional and global life-supporting atmosphere, soil, and water, can only be reduced (and ultimately controlled) by input management that involves increasing the efficiency of production systems and reducing the inputs of environmentally damaging materials. Input management requires a major change, an about-face, in the approach to management of agriculture, power plants, and industries because the focus is on waste reduction and recycling rather than on waste disposal. For large-scale ecosystem-level situations a top-down hierarchical approach is suggested and illustrated by recent research in agroecology and landscape ecology.

  8. Variable input parameter influence on river corridor prediction

    NARCIS (Netherlands)

    Zerfu, T.; Beevers, L.; Crosato, A.; Wright, N.

    2015-01-01

    This paper considers the erodible river corridor, which is the area in which the main river channel is free to migrate over a period of time. Due to growing anthropogenic pressure, predicting the corridor width has become increasingly important for the planning of development along rivers. Several a

  9. The Advanced LIGO Input Optics

    CERN Document Server

    Mueller, Chris; Ciani, Giacomo; DeRosa, Ryan; Effler, Anamaria; Feldbaum, David; Frolov, Valery; Fulda, Paul; Gleason, Joseph; Heintze, Matthew; King, Eleanor; Kokeyama, Keiko; Korth, William; Martin, Rodica; Mullavey, Adam; Poeld, Jan; Quetschke, Volker; Reitze, David; Tanner, David; Williams, Luke; Mueller, Guido

    2016-01-01

    The Advanced LIGO gravitational wave detectors are nearing their design sensitivity and should begin taking meaningful astrophysical data in the fall of 2015. These resonant optical interferometers will have unprecedented sensitivity to the strains caused by passing gravitational waves. The input optics play a significant part in allowing these devices to reach such sensitivities. Residing between the pre-stabilized laser and the main interferometer, the input optics is tasked with preparing the laser beam for interferometry at the sub-attometer level while operating at continuous wave input power levels ranging from 100 mW to 150 W. These extreme operating conditions required every major component to be custom designed. These designs draw heavily on the experience and understanding gained during the operation of Initial LIGO and Enhanced LIGO. In this article we report on how the components of the input optics were designed to meet their stringent requirements and present measurements showing how well they h...

  10. Nonlinear input-output systems

    Science.gov (United States)

    Hunt, L. R.; Luksic, Mladen; Su, Renjeng

    1987-01-01

    Necessary and sufficient conditions that the nonlinear system dot-x = f(x) + ug(x) and y = h(x) be locally feedback equivalent to the controllable linear system dot-xi = A xi + bv and y = C xi having linear output are found. Only the single input and single output case is considered, however, the results generalize to multi-input and multi-output systems.

  11. When Can Information from Ordinal Scale Variables Be Integrated?

    Science.gov (United States)

    Kemp, Simon; Grace, Randolph C.

    2010-01-01

    Many theoretical constructs of interest to psychologists are multidimensional and derive from the integration of several input variables. We show that input variables that are measured on ordinal scales cannot be combined to produce a stable weakly ordered output variable that allows trading off the input variables. Instead a partial order is…

  12. An alternative method for smartphone input using AR markers

    Directory of Open Access Journals (Sweden)

    Yuna Kang

    2014-07-01

    Full Text Available As smartphones came into wide use recently, it has become increasingly popular not only among young people, but among middle-aged people as well. Most smartphones adopt capacitive full touch screen, so touch commands are made by fingers unlike the PDAs in the past that use touch pens. In this case, a significant portion of the smartphone’s screen is blocked by the finger so it is impossible to see the screens around the finger touching the screen; this causes difficulties in making precise inputs. To solve this problem, this research proposes a method of using simple AR markers to improve the interface of smartphones. A marker is placed in front of the smartphone camera. Then, the camera image of the marker is analyzed to determine the position of the marker as the position of the mouse cursor. This method can enable click, double-click, drag-and-drop used in PCs as well as touch, slide, long-touch-input in smartphones. Through this research, smartphone inputs can be made more precise and simple, and show the possibility of the application of a new concept of smartphone interface.

  13. Depression Screening

    Science.gov (United States)

    ... Centers Diseases + Condition Centers Mental Health Medical Library Depression Screening (PHQ-9) - Instructions The following questions are ... this tool, there is also text-only version . Depression Screening - Manual Instructions The following questions are a ...

  14. Cancer Screening

    Directory of Open Access Journals (Sweden)

    Krishna Prasad

    2004-10-01

    Full Text Available Cancer screening is a means to detect cancer early with the goal of decreasing morbidity and mortality. At present, there is a reasonable consensus regarding screening for breast, cervical and colorectal cances and the role of screening is under trial in case of cancers of the lung,  ovaries and prostate. On the other hand, good screening tests are not available for some of the commonest cancers in India like the oral, pharyngeal, esophageal and stomach cancers.

  15. Cancer Screening

    OpenAIRE

    Krishna Prasad

    2004-01-01

    Cancer screening is a means to detect cancer early with the goal of decreasing morbidity and mortality. At present, there is a reasonable consensus regarding screening for breast, cervical and colorectal cances and the role of screening is under trial in case of cancers of the lung,  ovaries and prostate. On the other hand, good screening tests are not available for some of the commonest cancers in India like the oral, pharyngeal, esophageal and stomach cancers.

  16. Ensemble standar deviation of wind speed and direction of the FDDA input to WRF

    Data.gov (United States)

    U.S. Environmental Protection Agency — NetCDF file of the SREF standard deviation of wind speed and direction that was used to inject variability in the FDDA input. variable U_NDG_OLD contains standard...

  17. Agglomeration of mesoporous silica by melt and steam granulation. part II: screening of steam granulation process variables using a factorial design.

    Science.gov (United States)

    Vialpando, Monica; Albertini, Beatrice; Passerini, Nadia; Vander Heyden, Yvan; Rombaut, Patrick; Martens, Johan A; Van Den Mooter, Guy

    2013-11-01

    The objectives of this study were to identify the key process parameters during steam granulation of disordered mesoporous silica material Syloid® 244 FP (244) and to compare two different binders: polyvinylpyrrolidone (PVP) K25 and hydroxypropylmethyl cellulose (HPMC). Itraconazole (ITZ) was selected as the model compound for the development of an oral dosage form for enhanced release. Six factors: binder content, steam amount, mixing time, impeller speed, spray pause time, and filler content were investigated using a two-level quarter-fraction factorial design of experiment (DOE) for each binder type. As experimental responses, characteristics correlating to both granules and tablets were selected. Granules prepared from PVP resulted in an overall higher bulk density, granule size, increased flow properties, and better compression and compaction behavior. Although granulation with PVP resulted in the most ITZ to extract from the pores during processing, the premature drug release was less than 5%. The results of the DOE indicate that the risk of extracting the drug from the pores during processing is governed both by the process parameters and the binder properties. Centerpoint replicates of granules prepared with HPMC were highly variable.

  18. COGNITIVE INTERPRETATION OF INPUT HYPOTHESIS

    Institute of Scientific and Technical Information of China (English)

    WangHongyue; RenLiankui

    2004-01-01

    Krashen's Input Hypothesis, together with its earlier version, the Monitor Model is an influential theory in Second Language Acquisition research. In his studies, Krashen, on the one hand, emphasizes the part '“ comprehensible input” plays in learning a second language, on the other hand, he simply defines“comprehensible input” as “a little beyond the learner's current level”. What input can be considered as“a little beyond the learner's current level ”? Krashen gives no furtherexplanation. This paper tries to offer a more concrete and more detailed interpretation with Ausubel's Cognitive Assimilation theory.

  19. Input Hypothesis and its Controversy

    Institute of Scientific and Technical Information of China (English)

    金灵

    2016-01-01

    With Krashen's proposal of input hypothesis in 1980s, lots of contributions and further researches have been done in second language acquisition and teaching. Since it is impossible to undertake the exact empirical research to investigate its credibility, lots of criticisms are also aroused to disprove or adjust this hypothesis. However, due to its significant development in SLA, it is still valuable to explore the hypothesis and implications in language teaching to non-native speakers. This paper firstly focuses on the development of the input hypothesis, and then discusses some criticisms of this hypothesis.

  20. The Macaque Social Responsiveness Scale (mSRS: A Rapid Screening Tool for Assessing Variability in the Social Responsiveness of Rhesus Monkeys (Macaca mulatta.

    Directory of Open Access Journals (Sweden)

    Eric J Feczko

    Full Text Available Understanding the biological mechanisms underlying human neuropsychiatric disorders, such as autism spectrum disorder (ASD, has been hindered by the lack of a robust, translational animal model. Rhesus monkeys (Macaca mulatta display many of the same social behaviors that are affected in ASD, making them an excellent animal species in which to model social impairments. However, the social impairments associated with ASD may reflect extreme ends of a continuous distribution of traits. Thus, to validate the rhesus monkey as an animal model for studying social impairments that has strong translational relevance for ASD, researchers need an easily-implemented measurement tool that can quantify variation in social behavior dimensionally. The Social Responsiveness Scale (SRS is a 65-item survey that identifies both typical and atypical social behaviors in humans that covary with ASD symptom severity. A chimpanzee SRS has already been validated and the current study adapted this tool for use in the rhesus monkey (mSRS. Fifteen raters completed the mSRS for 105 rhesus monkeys living at the Yerkes National Primate Research Center. The mSRS scores showed a unimodal distribution with a positive skew that identified 6 statistical outliers. Inter-rater reliability was very strong, but only 17 of the 36 questions showed positive intra-item reliability. The results of an exploratory factor analysis identified 3 factors that explained over 60% of the variance, with 12 items significantly loading onto the primary factor. These items reflected behaviors associated with social avoidance, social anxiety or inflexibility and social confidence. These initial findings are encouraging and suggest that variability in the social responsiveness of rhesus monkeys can be quantified using the mSRS: a tool that has strong translational relevance for human disorders. With further modification, the mSRS may provide an promising new direction for research on the biological

  1. Double screening

    Energy Technology Data Exchange (ETDEWEB)

    Gratia, Pierre [Department of Physics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Hu, Wayne [Department of Astronomy and Astrophysics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Enrico Fermi Institute and Kavli Institute for Cosmological Physics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Joyce, Austin [Enrico Fermi Institute and Kavli Institute for Cosmological Physics, University of Chicago,South Ellis Avenue, Chicago, IL 60637 (United States); Ribeiro, Raquel H. [School of Physics and Astronomy, Queen Mary University of London,Mile End Road, London, E1 4NS (United Kingdom)

    2016-06-15

    Attempts to modify gravity in the infrared typically require a screening mechanism to ensure consistency with local tests of gravity. These screening mechanisms fit into three broad classes; we investigate theories which are capable of exhibiting more than one type of screening. Specifically, we focus on a simple model which exhibits both Vainshtein and kinetic screening. We point out that due to the two characteristic length scales in the problem, the type of screening that dominates depends on the mass of the sourcing object, allowing for different phenomenology at different scales. We consider embedding this double screening phenomenology in a broader cosmological scenario and show that the simplest examples that exhibit double screening are radiatively stable.

  2. Hybrid input function estimation using a single-input-multiple-output (SIMO) approach

    Science.gov (United States)

    Su, Yi; Shoghi, Kooresh I.

    2009-02-01

    A hybrid blood input function (BIF) model that incorporates region of interests (ROIs) based peak estimation and a two exponential tail model was proposed to describe the blood input function. The hybrid BIF model was applied to the single-input-multiple-output (SIMO) optimization based approach for BIF estimation using time activity curves (TACs) obtained from ROIs defined at left ventricle (LV) blood pool and myocardium regions of dynamic PET images. The proposed BIF estimation method was applied with 0, 1 and 2 blood samples as constraints for BIF estimation using simulated small animal PET data. Relative percentage difference of the area-under-curve (AUC) measurement between the estimated BIF and the true BIF was calculated to evaluate the BIF estimation accuracy. SIMO based BIF estimation using Feng's input function model was also applied for comparison. The hybrid method provided improved BIF estimation in terms of both mean accuracy and variability compared to Feng's model based BIF estimation in our simulation study. When two blood samples were used as constraints, the percentage BIF estimation error was 0.82 +/- 4.32% for the hybrid approach and 4.63 +/- 10.67% for the Feng's model based approach. Using hybrid BIF, improved kinetic parameter estimation was also obtained.

  3. World Input-Output Network.

    Directory of Open Access Journals (Sweden)

    Federica Cerina

    Full Text Available Production systems, traditionally analyzed as almost independent national systems, are increasingly connected on a global scale. Only recently becoming available, the World Input-Output Database (WIOD is one of the first efforts to construct the global multi-regional input-output (GMRIO tables. By viewing the world input-output system as an interdependent network where the nodes are the individual industries in different economies and the edges are the monetary goods flows between industries, we analyze respectively the global, regional, and local network properties of the so-called world input-output network (WION and document its evolution over time. At global level, we find that the industries are highly but asymmetrically connected, which implies that micro shocks can lead to macro fluctuations. At regional level, we find that the world production is still operated nationally or at most regionally as the communities detected are either individual economies or geographically well defined regions. Finally, at local level, for each industry we compare the network-based measures with the traditional methods of backward linkages. We find that the network-based measures such as PageRank centrality and community coreness measure can give valuable insights into identifying the key industries.

  4. On Adaptive Optimal Input Design

    NARCIS (Netherlands)

    Stigter, J.D.; Vries, D.; Keesman, K.J.

    2003-01-01

    The problem of optimal input design (OID) for a fed-batch bioreactor case study is solved recursively. Here an adaptive receding horizon optimal control problem, involving the so-called E-criterion, is solved on-line, using the current estimate of the parameter vector at each sample instant {tk, k =

  5. World Input-Output Network

    Science.gov (United States)

    Cerina, Federica; Zhu, Zhen; Chessa, Alessandro; Riccaboni, Massimo

    2015-01-01

    Production systems, traditionally analyzed as almost independent national systems, are increasingly connected on a global scale. Only recently becoming available, the World Input-Output Database (WIOD) is one of the first efforts to construct the global multi-regional input-output (GMRIO) tables. By viewing the world input-output system as an interdependent network where the nodes are the individual industries in different economies and the edges are the monetary goods flows between industries, we analyze respectively the global, regional, and local network properties of the so-called world input-output network (WION) and document its evolution over time. At global level, we find that the industries are highly but asymmetrically connected, which implies that micro shocks can lead to macro fluctuations. At regional level, we find that the world production is still operated nationally or at most regionally as the communities detected are either individual economies or geographically well defined regions. Finally, at local level, for each industry we compare the network-based measures with the traditional methods of backward linkages. We find that the network-based measures such as PageRank centrality and community coreness measure can give valuable insights into identifying the key industries. PMID:26222389

  6. Input in an Institutional Setting.

    Science.gov (United States)

    Bardovi-Harlig, Kathleen; Hartford, Beverly S.

    1996-01-01

    Investigates the nature of input available to learners in the institutional setting of the academic advising session. Results indicate that evidence for the realization of speech acts, positive evidence from peers and status unequals, the effect of stereotypes, and limitations of a learner's pragmatic and grammatical competence are influential…

  7. Optimal Inputs for System Identification.

    Science.gov (United States)

    1995-09-01

    The derivation of the power spectral density of the optimal input for system identification is addressed in this research. Optimality is defined in...identification potential of general System Identification algorithms, a new and efficient System Identification algorithm that employs Iterated Weighted Least

  8. Analog Input Data Acquisition Software

    Science.gov (United States)

    Arens, Ellen

    2009-01-01

    DAQ Master Software allows users to easily set up a system to monitor up to five analog input channels and save the data after acquisition. This program was written in LabVIEW 8.0, and requires the LabVIEW runtime engine 8.0 to run the executable.

  9. Remote input/output station

    CERN Multimedia

    1972-01-01

    A general view of the remote input/output station installed in building 112 (ISR) and used for submitting jobs to the CDC 6500 and 6600. The card reader on the left and the line printer on the right are operated by programmers on a self-service basis.

  10. World Input-Output Network.

    Science.gov (United States)

    Cerina, Federica; Zhu, Zhen; Chessa, Alessandro; Riccaboni, Massimo

    2015-01-01

    Production systems, traditionally analyzed as almost independent national systems, are increasingly connected on a global scale. Only recently becoming available, the World Input-Output Database (WIOD) is one of the first efforts to construct the global multi-regional input-output (GMRIO) tables. By viewing the world input-output system as an interdependent network where the nodes are the individual industries in different economies and the edges are the monetary goods flows between industries, we analyze respectively the global, regional, and local network properties of the so-called world input-output network (WION) and document its evolution over time. At global level, we find that the industries are highly but asymmetrically connected, which implies that micro shocks can lead to macro fluctuations. At regional level, we find that the world production is still operated nationally or at most regionally as the communities detected are either individual economies or geographically well defined regions. Finally, at local level, for each industry we compare the network-based measures with the traditional methods of backward linkages. We find that the network-based measures such as PageRank centrality and community coreness measure can give valuable insights into identifying the key industries.

  11. Input/output interface module

    Science.gov (United States)

    Ozyazici, E. M.

    1980-01-01

    Module detects level changes in any of its 16 inputs, transfers changes to its outputs, and generates interrupts when changes are detected. Up to four changes-in-state per line are stored for later retrieval by controlling computer. Using standard TTL logic, module fits 19-inch rack-mounted console.

  12. The advanced LIGO input optics

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Chris L., E-mail: cmueller@phys.ufl.edu; Arain, Muzammil A.; Ciani, Giacomo; Feldbaum, David; Fulda, Paul; Gleason, Joseph; Heintze, Matthew; Martin, Rodica M.; Reitze, David H.; Tanner, David B.; Williams, Luke F.; Mueller, Guido [University of Florida, Gainesville, Florida 32611 (United States); DeRosa, Ryan T.; Effler, Anamaria; Kokeyama, Keiko [Louisiana State University, Baton Rouge, Louisiana 70803 (United States); Frolov, Valery V.; Mullavey, Adam [LIGO Livingston Observatory, Livingston, Louisiana 70754 (United States); Kawabe, Keita; Vorvick, Cheryl [LIGO Hanford Observatory, Richland, Washington 99352 (United States); King, Eleanor J. [University of Adelaide, Adelaide, SA 5005 (Australia); and others

    2016-01-15

    The advanced LIGO gravitational wave detectors are nearing their design sensitivity and should begin taking meaningful astrophysical data in the fall of 2015. These resonant optical interferometers will have unprecedented sensitivity to the strains caused by passing gravitational waves. The input optics play a significant part in allowing these devices to reach such sensitivities. Residing between the pre-stabilized laser and the main interferometer, the input optics subsystem is tasked with preparing the laser beam for interferometry at the sub-attometer level while operating at continuous wave input power levels ranging from 100 mW to 150 W. These extreme operating conditions required every major component to be custom designed. These designs draw heavily on the experience and understanding gained during the operation of Initial LIGO and Enhanced LIGO. In this article, we report on how the components of the input optics were designed to meet their stringent requirements and present measurements showing how well they have lived up to their design.

  13. Colon cancer screening

    Science.gov (United States)

    Screening for colon cancer; Colonoscopy - screening; Sigmoidoscopy - screening; Virtual colonoscopy - screening; Fecal immunochemical test; Stool DNA test; sDNA test; Colorectal cancer - screening; Rectal ...

  14. Study of Chunks Input Approach

    Institute of Scientific and Technical Information of China (English)

    马静

    2003-01-01

    This paper is to describe and investigate Chunks (Lexical Phrases ) Input Approach in vocabulary learning strategies by means of achievement tests,questionnaire surveys and interviews. The study is to reveal how different learners combine different vocabulary learning strategies in their learning process. With the data collected, the author of this paper discusses and summarizes learners' individual differences in selecting vocabulary learning strategies with the hope of giving new insights into English teaching and learning.

  15. Distributed and Mixed Information in Monosynaptic Inputs to Dopamine Neurons.

    Science.gov (United States)

    Tian, Ju; Huang, Ryan; Cohen, Jeremiah Y; Osakada, Fumitaka; Kobak, Dmitry; Machens, Christian K; Callaway, Edward M; Uchida, Naoshige; Watabe-Uchida, Mitsuko

    2016-09-21

    Dopamine neurons encode the difference between actual and predicted reward, or reward prediction error (RPE). Although many models have been proposed to account for this computation, it has been difficult to test these models experimentally. Here we established an awake electrophysiological recording system, combined with rabies virus and optogenetic cell-type identification, to characterize the firing patterns of monosynaptic inputs to dopamine neurons while mice performed classical conditioning tasks. We found that each variable required to compute RPE, including actual and predicted reward, was distributed in input neurons in multiple brain areas. Further, many input neurons across brain areas signaled combinations of these variables. These results demonstrate that even simple arithmetic computations such as RPE are not localized in specific brain areas but, rather, distributed across multiple nodes in a brain-wide network. Our systematic method to examine both activity and connectivity revealed unexpected redundancy for a simple computation in the brain.

  16. Does Input Quality Drive Measured Differences in Firm Productivity?

    DEFF Research Database (Denmark)

    Fox, Jeremy T.; Smeets, Valerie Anne Rolande

    Firms in the same industry can differ in measured productivity by multiples of 3. Griliches (1957) suggests one explanation: the quality of inputs differs across firms. We add labor market history variables such as experience and firm and industry tenure, as well as general human capital measures...

  17. Rational Expansion for Nonlinear Input-Output Maps

    OpenAIRE

    1988-01-01

    This paper introduces a Rational Expansion for Nonlinear Input-Output MAPS. The method is new and is based on the rational expansion of functions of several complex variables. If truncated, this series reduces to a ratio of truncated Volterra series, A "feedback form" will be presented.

  18. Sensitivity of Monte Carlo simulations to input distributions

    Energy Technology Data Exchange (ETDEWEB)

    RamoRao, B. S.; Srikanta Mishra, S.; McNeish, J.; Andrews, R. W.

    2001-07-01

    The sensitivity of the results of a Monte Carlo simulation to the shapes and moments of the probability distributions of the input variables is studied. An economical computational scheme is presented as an alternative to the replicate Monte Carlo simulations and is explained with an illustrative example. (Author) 4 refs.

  19. Ground motion input in seismic evaluation studies

    Energy Technology Data Exchange (ETDEWEB)

    Sewell, R.T.; Wu, S.C.

    1996-07-01

    This report documents research pertaining to conservatism and variability in seismic risk estimates. Specifically, it examines whether or not artificial motions produce unrealistic evaluation demands, i.e., demands significantly inconsistent with those expected from real earthquake motions. To study these issues, two types of artificial motions are considered: (a) motions with smooth response spectra, and (b) motions with realistic variations in spectral amplitude across vibration frequency. For both types of artificial motion, time histories are generated to match target spectral shapes. For comparison, empirical motions representative of those that might result from strong earthquakes in the Eastern U.S. are also considered. The study findings suggest that artificial motions resulting from typical simulation approaches (aimed at matching a given target spectrum) are generally adequate and appropriate in representing the peak-response demands that may be induced in linear structures and equipment responding to real earthquake motions. Also, given similar input Fourier energies at high-frequencies, levels of input Fourier energy at low frequencies observed for artificial motions are substantially similar to those levels noted in real earthquake motions. In addition, the study reveals specific problems resulting from the application of Western U.S. type motions for seismic evaluation of Eastern U.S. nuclear power plants.

  20. Screening CO

    NARCIS (Netherlands)

    Ramírez, A.; Hagedoorn, S.; Kramers, L.; Wildenborg, T.; Hendriks, C.

    2010-01-01

    This paper describes the development and application of a methodology to screen and rank Dutch reservoirs suitable for long-term large scale CO2 storage. The screening focuses on off- and on-shore individual aquifers, gas and oil fields. In total 176 storage reservoirs have been taken int

  1. Choice of input fields in stochastic finite elements

    DEFF Research Database (Denmark)

    Ditlevsen, Ove Dalager; Tarp-Johansen, Niels Jacob

    1999-01-01

    , the flexibility field, as the input to the stochastic finite element model. To answer this question the focus should be on the error of the output of the mechanical model rather than on the input field itself when discretizing the held through replacing it by a field defined in terms of a finite number of random...... variables. Several reported discretization methods define these random variables as integrals of the product of the held and some suitable weight functions. In particular, the weight functions can be Dirac delta functions whereby the random variables become the field values at a finite set of given points....... The replacement field is often defined as the linear regression of the original field on the considered vector of the weighted integrals of the field. For example, this holds for discretizations obtained by truncation of the Karhunen-Loeve expansion of the field, but only approximately so for truncations...

  2. Choice of input fields in stochastic finite elements

    DEFF Research Database (Denmark)

    Ditlevsen, Ove Dalager; Tarp-Johansen, Niels Jacob

    1996-01-01

    , the flexibility field, as the input to the stochastic finite element model. To answer this question the focus should be on the error of the output of the mechanical model rather than on the input field itself when discretizing the field through replacing it by a field defined in terms of a finite number of random...... variables. Several reported discretization methods define these random variables as integrals of the product of the field and some suitable weight functions. In particular, the weight functions can be Dirac delta functions whereby the random variables become the field values at a finite set of given points....... The replacement field is often defined as the linear regression of the original field on the considered vector of the weighted integrals of the field. For example, this holds for discretizations obtained by truncation of the Karhunen-Loeve expansion of the field, but only approximately so for truncations...

  3. Screening and metamodeling of computer experiments with functional outputs. Application to thermal-hydraulic computations

    CERN Document Server

    Auder, Benjamin; Iooss, Bertrand; Marques, Michel

    2010-01-01

    To perform uncertainty, sensitivity or optimization analysis on scalar variables calculated by a cpu time expensive computer code, a widely accepted methodology consists in first identifying the most influential uncertain inputs (by screening techniques), and then in replacing the cpu time expensive model by a cpu inexpensive mathematical function, called a metamodel. This paper extends this methodology to the functional output case, for instance when the model output variables are curves. The screening approach is based on the analysis of variance and principal component analysis of output curves. The functional metamodeling consists in a curve classification step, a dimension reduction step, then a classical metamodeling step. An industrial nuclear reactor application (dealing with uncertainties in the pressurized thermal shock analysis) illustrates all these steps.

  4. Optimal Input Design for Aircraft Parameter Estimation using Dynamic Programming Principles

    Science.gov (United States)

    Morelli, Eugene A.; Klein, Vladislav

    1990-01-01

    A new technique was developed for designing optimal flight test inputs for aircraft parameter estimation experiments. The principles of dynamic programming were used for the design in the time domain. This approach made it possible to include realistic practical constraints on the input and output variables. A description of the new approach is presented, followed by an example for a multiple input linear model describing the lateral dynamics of a fighter aircraft. The optimal input designs produced by the new technique demonstrated improved quality and expanded capability relative to the conventional multiple input design method.

  5. Quadruple screen test

    Science.gov (United States)

    Quad screen; Multiple marker screening; AFP plus; Triple screen test; AFP maternal; MSAFP; 4-marker screen; Down syndrome - quadruple; Trisomy 21 - quadruple; Turner syndrome - quadruple; Spina bifida - ...

  6. Toxicology screen

    Science.gov (United States)

    Toxicology screening is most often done using a blood or urine sample. However, it may be done soon after the person swallowed the medication, using stomach contents taken through gastric lavage (stomach pumping) or after vomiting.

  7. Hypertension screening

    Science.gov (United States)

    Foulke, J. M.

    1975-01-01

    An attempt was made to measure the response to an announcement of hypertension screening at the Goddard Space Center, to compare the results to those of previous statistics. Education and patient awareness of the problem were stressed.

  8. Hypertension screening

    Science.gov (United States)

    Foulke, J. M.

    1975-01-01

    An attempt was made to measure the response to an announcement of hypertension screening at the Goddard Space Center, to compare the results to those of previous statistics. Education and patient awareness of the problem were stressed.

  9. Effects of input uncertainty on cross-scale crop modeling

    Science.gov (United States)

    Waha, Katharina; Huth, Neil; Carberry, Peter

    2014-05-01

    The quality of data on climate, soils and agricultural management in the tropics is in general low or data is scarce leading to uncertainty in process-based modeling of cropping systems. Process-based crop models are common tools for simulating crop yields and crop production in climate change impact studies, studies on mitigation and adaptation options or food security studies. Crop modelers are concerned about input data accuracy as this, together with an adequate representation of plant physiology processes and choice of model parameters, are the key factors for a reliable simulation. For example, assuming an error in measurements of air temperature, radiation and precipitation of ± 0.2°C, ± 2 % and ± 3 % respectively, Fodor & Kovacs (2005) estimate that this translates into an uncertainty of 5-7 % in yield and biomass simulations. In our study we seek to answer the following questions: (1) are there important uncertainties in the spatial variability of simulated crop yields on the grid-cell level displayed on maps, (2) are there important uncertainties in the temporal variability of simulated crop yields on the aggregated, national level displayed in time-series, and (3) how does the accuracy of different soil, climate and management information influence the simulated crop yields in two crop models designed for use at different spatial scales? The study will help to determine whether more detailed information improves the simulations and to advise model users on the uncertainty related to input data. We analyse the performance of the point-scale crop model APSIM (Keating et al., 2003) and the global scale crop model LPJmL (Bondeau et al., 2007) with different climate information (monthly and daily) and soil conditions (global soil map and African soil map) under different agricultural management (uniform and variable sowing dates) for the low-input maize-growing areas in Burkina Faso/West Africa. We test the models' response to different levels of input

  10. HCC screening; HCC-Screening

    Energy Technology Data Exchange (ETDEWEB)

    Albrecht, T. [Charite-Unversitaetsmedizin,Freie Universitaet und Humboldt-Universitaet zu Berlin, Klinik und Hochschulambulanz fuer Radiologie und Nuklearmedizin,Campus Benjamin Franklin, Berlin (Germany)

    2008-01-15

    Hepatocellular carcinoma (HCC) is one of the most frequently diagnosed tumour diseases throughout the world. In the vast majority of cases those affected are high-risk patients with chronic viral hepatitis and/or liver cirrhosis, which means there is a clearly identifiable target group for HCC screening. With resection, transplantation, and interventional procedures for local ablation, following early diagnosis curative treatment options are available with which 5-year survival rates of over 60% can be reached. Such early diagnosis is a reality only in a minority of patients, however, and in the majority of cases the disease is already in an advanced stage at diagnosis. One of the objects of HCC screening is diagnosis in an early stage when curative treatment is still possible. Precisely this is achieved by screening, so that the proportion of patients treated with curative intent is decisively higher. There is not yet any clear evidence as to whether this leads to a lowering of the mortality of HCC. As lower mortality is the decisive indicator of success for a screening programme the benefit of HCC screening has so far been neither documented nor refuted. Nonetheless, in large regions of the world it is the practice for high-risk patients to undergo HCC screening in the form of twice-yearly ultrasound examination and determination of AFP. (orig.) [German] Das hepatozellulaere Karzinom (HCC) ist eine der weltweit haeufigsten Tumorerkrankungen. Es tritt in der grossen Mehrzahl der Faelle bei Hochrisikopatienten mit chronischer Virushepatitis bzw. Leberzirrhose auf, woraus sich eine klar identifizierbare Zielgruppe fuer das HCC-Screening ergibt. Mit der Resektion, der Transplantation und interventionellen lokal ablativen Verfahren stehen bei rechtzeitiger Diagnosestellung kurative Therapieoptionen zur Verfuegung, die 5-Jahres-Ueberlebensraten von >60% erreichen. Diese rechtzeitige Diagnosestellung erfolgt jedoch nur bei einer Minderzahl der Patienten, waehrend die

  11. Repositioning Recitation Input in College English Teaching

    Science.gov (United States)

    Xu, Qing

    2009-01-01

    This paper tries to discuss how recitation input helps overcome the negative influences on the basis of second language acquisition theory and confirms the important role that recitation input plays in improving college students' oral and written English.

  12. A Practical pedestrian approach to parsimonious regression with inaccurate inputs

    Directory of Open Access Journals (Sweden)

    Seppo Karrila

    2014-04-01

    Full Text Available A measurement result often dictates an interval containing the correct value. Interval data is also created by roundoff, truncation, and binning. We focus on such common interval uncertainty in data. Inaccuracy in model inputs is typically ignored on model fitting. We provide a practical approach for regression with inaccurate data: the mathematics is easy, and the linear programming formulations simple to use even in a spreadsheet. This self-contained elementary presentation introduces interval linear systems and requires only basic knowledge of algebra. Feature selection is automatic; but can be controlled to find only a few most relevant inputs; and joint feature selection is enabled for multiple modeled outputs. With more features than cases, a novel connection to compressed sensing emerges: robustness against interval errors-in-variables implies model parsimony, and the input inaccuracies determine the regularization term. A small numerical example highlights counterintuitive results and a dramatic difference to total least squares.

  13. Linearisation via input-output injection of time delay systems

    Science.gov (United States)

    García-Ramírez, Eduardo; Moog, Claude H.; Califano, Claudia; Alejandro Márquez-Martínez, Luis

    2016-06-01

    This paper deals with the problem of linearisation of systems with constant commensurable delays by input-output injection using algebraic control tools based on the theory of non-commutative rings. Solutions for the problem of linearisation free of delays, and with delays of an observable nonlinear time-delay systems are presented based on the analysis of the input-output equation. These results are achieved by means of constructive algorithms that use the nth derivative of the output expressed in terms of the state-space variables instead of the explicit computation of the input-output representation of the system. Necessary and sufficient conditions are established in both cases by means of an invertible change of coordinates.

  14. Facilitating agricultural input distribution in Uganda - Experiences ...

    African Journals Online (AJOL)

    Mo

    The input supply market however, suffered a setback as a result of the ... Ltd. redefined the approach emphasizing a demand driven input market by shifting ... Training of business entrepreneurs in business planning, ... The strategy to increase rural demand for agricultural inputs ..... During season 2004A, the basic fertilizers.

  15. Effects of Auditory Input in Individuation Tasks

    Science.gov (United States)

    Robinson, Christopher W.; Sloutsky, Vladimir M.

    2008-01-01

    Under many conditions auditory input interferes with visual processing, especially early in development. These interference effects are often more pronounced when the auditory input is unfamiliar than when the auditory input is familiar (e.g. human speech, pre-familiarized sounds, etc.). The current study extends this research by examining how…

  16. 7 CFR 3430.607 - Stakeholder input.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Stakeholder input. 3430.607 Section 3430.607 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION... § 3430.607 Stakeholder input. CSREES shall seek and obtain stakeholder input through a variety of...

  17. 7 CFR 3430.15 - Stakeholder input.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Stakeholder input. 3430.15 Section 3430.15... Stakeholder input. Section 103(c)(2) of the Agricultural Research, Extension, and Education Reform Act of 1998... RFAs for competitive programs. CSREES will provide instructions for submission of stakeholder input...

  18. 7 CFR 3430.907 - Stakeholder input.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Stakeholder input. 3430.907 Section 3430.907 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION... Program § 3430.907 Stakeholder input. CSREES shall seek and obtain stakeholder input through a variety...

  19. A Latent Variable Investigation of the Phonological Awareness Literacy Screening-Kindergarten Assessment: Construct Identification and Multigroup Comparisons between Spanish-Speaking English-Language Learners (ELLs) and Non-ELL Students

    Science.gov (United States)

    Huang, Francis L.; Konold, Timothy R.

    2014-01-01

    Psychometric properties of the Phonological Awareness Literacy Screening for Kindergarten (PALS-K) instrument were investigated in a sample of 2844 first-time public school kindergarteners. PALS-K is a widely used English literacy screening assessment. Exploratory factor analysis revealed a theoretically defensible measurement structure that was…

  20. Control Board Digital Interface Input Devices – Touchscreen, Trackpad, or Mouse?

    Energy Technology Data Exchange (ETDEWEB)

    Thomas A. Ulrich; Ronald L. Boring; Roger Lew

    2015-08-01

    The authors collaborated with a power utility to evaluate input devices for use in the human system interface (HSI) for a new digital Turbine Control System (TCS) at a nuclear power plant (NPP) undergoing a TCS upgrade. A standalone dynamic software simulation of the new digital TCS and a mobile kiosk were developed to conduct an input device study to evaluate operator preference and input device effectiveness. The TCS software presented the anticipated HSI for the TCS and mimicked (i.e., simulated) the turbine systems’ responses to operator commands. Twenty-four licensed operators from the two nuclear power units participated in the study. Three input devices were tested: a trackpad, mouse, and touchscreen. The subjective feedback from the survey indicates the operators preferred the touchscreen interface. The operators subjectively rated the touchscreen as the fastest and most comfortable input device given the range of tasks they performed during the study, but also noted a lack of accuracy for selecting small targets. The empirical data suggest the mouse input device provides the most consistent performance for screen navigation and manipulating on screen controls. The trackpad input device was both empirically and subjectively found to be the least effective and least desired input device.

  1. Input calibration for negative originals

    Science.gov (United States)

    Tuijn, Chris

    1995-04-01

    One of the major challenges in the prepress environment consists of controlling the electronic color reproduction process such that a perfect match of any original can be realized. Whether this goal can be reached depends on many factors such as the dynamic range of the input device (scanner, camera), the color gamut of the output device (dye sublimation printer, ink-jet printer, offset), the color management software etc. The characterization of the color behavior of the peripheral devices is therefore very important. Photographs and positive transparents reflect the original scene pretty well; for negative originals, however, there is no obvious link to either the original scene or a particular print of the negative under consideration. In this paper, we establish a method to scan negatives and to convert the scanned data to a calibrated RGB space, which is known colorimetrically. This method is based on the reconstruction of the original exposure conditions (i.e., original scene) which generated the negative. Since the characteristics of negative film are quite diverse, a special calibration is required for each combination of scanner and film type.

  2. Esophageal Cancer Screening

    Science.gov (United States)

    ... Esophageal Cancer Prevention Esophageal Cancer Screening Research Esophageal Cancer Screening (PDQ®)–Patient Version What is screening? Go to ... the esophagus and the stomach). Being overweight . Esophageal Cancer Screening Key Points Tests are used to screen for ...

  3. Controlling chaos in balanced neural circuits with input spike trains

    Science.gov (United States)

    Engelken, Rainer; Wolf, Fred

    The cerebral cortex can be seen as a system of neural circuits driving each other with spike trains. Here we study how the statistics of these spike trains affects chaos in balanced target circuits.Earlier studies of chaos in balanced neural circuits either used a fixed input [van Vreeswijk, Sompolinsky 1996, Monteforte, Wolf 2010] or white noise [Lajoie et al. 2014]. We study dynamical stability of balanced networks driven by input spike trains with variable statistics. The analytically obtained Jacobian enables us to calculate the complete Lyapunov spectrum. We solved the dynamics in event-based simulations and calculated Lyapunov spectra, entropy production rate and attractor dimension. We vary correlations, irregularity, coupling strength and spike rate of the input and action potential onset rapidness of recurrent neurons.We generally find a suppression of chaos by input spike trains. This is strengthened by bursty and correlated input spike trains and increased action potential onset rapidness. We find a link between response reliability and the Lyapunov spectrum. Our study extends findings in chaotic rate models [Molgedey et al. 1992] to spiking neuron models and opens a novel avenue to study the role of projections in shaping the dynamics of large neural circuits.

  4. Optimization of precipitation inputs for SWAT modeling in mountainous catchment

    Science.gov (United States)

    Tuo, Ye; Chiogna, Gabriele; Disse, Markus

    2016-04-01

    Precipitation is often the most important input data in hydrological models when simulating streamflow in mountainous catchment. The Soil and Water Assessment Tool (SWAT), a widely used hydrological model, only makes use of data from one precipitation gauging station which is nearest to the centroid of each subcatchment, eventually corrected using the band elevation method. This leads in general to inaccurate subcatchment precipitation representation, which results in unreliable simulation results in mountainous catchment. To investigate the impact of the precipitation inputs and consider the high spatial and temporal variability of precipitation, we first interpolated 21 years (1990-2010) of daily measured data using the Inverse Distance Weighting (IDW) method. Averaged IDW daily values have been calculated at the subcatchment scale to be further supplied as optimized precipitation inputs for SWAT. Both datasets (Measured data and IDW data) are applied to three Alpine subcatchments of the Adige catchment (North-eastern Italy, 12100 km2) as precipitation inputs. Based on the calibration and validation results, model performances are evaluated according to the Nash Sutchliffe Efficiency (NSE) and Coefficient of Determination (R2). For all three subcatchments, the simulation results with IDW inputs are better than the original method which uses measured inputs from the nearest station. This suggests that IDW method could improve the model performance in Alpine catchments to some extent. By taking into account and weighting the distance between precipitation records, IDW supplies more accurate precipitation inputs for each individual Alpine subcatchment, which would as a whole lead to an improved description of the hydrological behavior of the entire Adige catchment.

  5. Turn customer input into innovation.

    Science.gov (United States)

    Ulwick, Anthony W

    2002-01-01

    It's difficult to find a company these days that doesn't strive to be customer-driven. Too bad, then, that most companies go about the process of listening to customers all wrong--so wrong, in fact, that they undermine innovation and, ultimately, the bottom line. What usually happens is this: Companies ask their customers what they want. Customers offer solutions in the form of products or services. Companies then deliver these tangibles, and customers just don't buy. The reason is simple--customers aren't expert or informed enough to come up with solutions. That's what your R&D team is for. Rather, customers should be asked only for outcomes--what they want a new product or service to do for them. The form the solutions take should be up to you, and you alone. Using Cordis Corporation as an example, this article describes, in fine detail, a series of effective steps for capturing, analyzing, and utilizing customer input. First come indepth interviews, in which a moderator works with customers to deconstruct a process or activity in order to unearth "desired outcomes." Addressing participants' comments one at a time, the moderator rephrases them to be both unambiguous and measurable. Once the interviews are complete, researchers then compile a comprehensive list of outcomes that participants rank in order of importance and degree to which they are satisfied by existing products. Finally, using a simple mathematical formula called the "opportunity calculation," researchers can learn the relative attractiveness of key opportunity areas. These data can be used to uncover opportunities for product development, to properly segment markets, and to conduct competitive analysis.

  6. SCREEN CUISINE

    National Research Council Canada - National Science Library

    Heather Baysa

    2010-01-01

    ... from the legendary restaurant; the World's First FoodTruck Drive-In Movie on Saturday, where the city's finest food-truck vendors park for the screenings; and the Brooklyn Burger W Beer Garden on Sunday, serving up hearty burgers and brews while you watch Anat Baron's Beer Wars. Tonight at 7, Water Taxi Beach, South Street Seaport.fest...

  7. Airport Screening

    Science.gov (United States)

    ... must be limited to a safe level. An American National Standards Institute/Health Physics Society industry standard states that the maxi- mum ... that does not directly damage DNA. 2 References American National ... Physics Society. Radiation safety for personnel security screening systems ...

  8. Global sensitivity analysis approach for input selection and system identification purposes--a new framework for feedforward neural networks.

    Science.gov (United States)

    Fock, Eric

    2014-08-01

    A new algorithm for the selection of input variables of neural network is proposed. This new method, applied after the training stage, ranks the inputs according to their importance in the variance of the model output. The use of a global sensitivity analysis technique, extended Fourier amplitude sensitivity test, gives the total sensitivity index for each variable, which allows for the ranking and the removal of the less relevant inputs. Applied to some benchmarking problems in the field of features selection, the proposed approach shows good agreement in keeping the relevant variables. This new method is a useful tool for removing superfluous inputs and for system identification.

  9. Estimating latency from inhibitory input

    DEFF Research Database (Denmark)

    Levakova, Marie; Ditlevsen, Susanne; Lansky, Petr

    2014-01-01

    to the stimulus by an increase in the firing rate. We focus on the estimation of the response latency in the case of inhibitory stimuli. Models used in this paper represent two different descriptions of response latency. We consider either the latency to be constant across trials or to be a random variable......Stimulus response latency is the time period between the presentation of a stimulus and the occurrence of a change in the neural firing evoked by the stimulation. The response latency has been explored and estimation methods proposed mostly for excitatory stimuli, which means that the neuron reacts....... In the case of random latency, special attention is given to models with selective interaction. The aim is to propose methods for estimation of the latency or the parameters of its distribution. Parameters are estimated by four different methods: method of moments, maximum-likelihood method, a method...

  10. Predictor variables of clergy pedophiles.

    Science.gov (United States)

    Ruzicka, M F

    1997-10-01

    File data on familial traits, past sexual experience as a victim, and other traits identified in the literature as leading toward pedophilia, were summarized for 10 convicted clergy pedophiles to construct a set of variables possibly useful for screening. Further research is underway to identify trauma in early life and those personality-related variables current studies indicate as relevant.

  11. Input estimation from measured structural response

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, Dustin [Los Alamos National Laboratory; Cross, Elizabeth [Los Alamos National Laboratory; Silva, Ramon A [Los Alamos National Laboratory; Farrar, Charles R [Los Alamos National Laboratory; Bement, Matt [Los Alamos National Laboratory

    2009-01-01

    This report will focus on the estimation of unmeasured dynamic inputs to a structure given a numerical model of the structure and measured response acquired at discrete locations. While the estimation of inputs has not received as much attention historically as state estimation, there are many applications where an improved understanding of the immeasurable input to a structure is vital (e.g. validating temporally varying and spatially-varying load models for large structures such as buildings and ships). In this paper, the introduction contains a brief summary of previous input estimation studies. Next, an adjoint-based optimization method is used to estimate dynamic inputs to two experimental structures. The technique is evaluated in simulation and with experimental data both on a cantilever beam and on a three-story frame structure. The performance and limitations of the adjoint-based input estimation technique are discussed.

  12. Input Method "Five Strokes": Advantages and Problems

    Directory of Open Access Journals (Sweden)

    Mateja PETROVČIČ

    2014-03-01

    Since the Five Stroke input method is easily accessible, simple to master and is not pronunciation-based, we would expect that the students will use it to input unknown characters. The survey comprises students of Japanology and Sinology at Department of Asian and African Studies, takes in consideration the grade of the respondent and therefore his/her knowledge of characters. This paper also discusses the impact of typeface to the accuracy of the input.

  13. Bilinearity in spatiotemporal integration of synaptic inputs.

    Directory of Open Access Journals (Sweden)

    Songting Li

    2014-12-01

    Full Text Available Neurons process information via integration of synaptic inputs from dendrites. Many experimental results demonstrate dendritic integration could be highly nonlinear, yet few theoretical analyses have been performed to obtain a precise quantitative characterization analytically. Based on asymptotic analysis of a two-compartment passive cable model, given a pair of time-dependent synaptic conductance inputs, we derive a bilinear spatiotemporal dendritic integration rule. The summed somatic potential can be well approximated by the linear summation of the two postsynaptic potentials elicited separately, plus a third additional bilinear term proportional to their product with a proportionality coefficient [Formula: see text]. The rule is valid for a pair of synaptic inputs of all types, including excitation-inhibition, excitation-excitation, and inhibition-inhibition. In addition, the rule is valid during the whole dendritic integration process for a pair of synaptic inputs with arbitrary input time differences and input locations. The coefficient [Formula: see text] is demonstrated to be nearly independent of the input strengths but is dependent on input times and input locations. This rule is then verified through simulation of a realistic pyramidal neuron model and in electrophysiological experiments of rat hippocampal CA1 neurons. The rule is further generalized to describe the spatiotemporal dendritic integration of multiple excitatory and inhibitory synaptic inputs. The integration of multiple inputs can be decomposed into the sum of all possible pairwise integration, where each paired integration obeys the bilinear rule. This decomposition leads to a graph representation of dendritic integration, which can be viewed as functionally sparse.

  14. Immobilized OBOC combinatorial bead array to facilitate multiplicative screening

    OpenAIRE

    Xiao, Wenwu; Bononi, Fernanda C.; Townsend, Jared; Li, Yuanpei; Liu, Ruiwu; Lam, Kit S.

    2013-01-01

    One-bead-one-compound (OBOC) combinatorial library screening has been broadly utilized for the last two decades to identify small molecules, peptides or peptidomimetics targeting variable screening probes such as cell surface receptors, bacteria, protein kinases, phosphatases, proteases etc. In previous screening methods, library beads were suspended in solution and screened against one single probe. Only the positive beads were tracked and isolated for additional screens and finally selected...

  15. Breast cancer screening

    Science.gov (United States)

    Mammogram - breast cancer screening; Breast exam - breast cancer screening; MRI - breast cancer screening ... performed to screen women to detect early breast cancer when it is more likely to be cured. ...

  16. Rapid Airplane Parametric Input Design (RAPID)

    Science.gov (United States)

    Smith, Robert E.

    1995-01-01

    RAPID is a methodology and software system to define a class of airplane configurations and directly evaluate surface grids, volume grids, and grid sensitivity on and about the configurations. A distinguishing characteristic which separates RAPID from other airplane surface modellers is that the output grids and grid sensitivity are directly applicable in CFD analysis. A small set of design parameters and grid control parameters govern the process which is incorporated into interactive software for 'real time' visual analysis and into batch software for the application of optimization technology. The computed surface grids and volume grids are suitable for a wide range of Computational Fluid Dynamics (CFD) simulation. The general airplane configuration has wing, fuselage, horizontal tail, and vertical tail components. The double-delta wing and tail components are manifested by solving a fourth order partial differential equation (PDE) subject to Dirichlet and Neumann boundary conditions. The design parameters are incorporated into the boundary conditions and therefore govern the shapes of the surfaces. The PDE solution yields a smooth transition between boundaries. Surface grids suitable for CFD calculation are created by establishing an H-type topology about the configuration and incorporating grid spacing functions in the PDE equation for the lifting components and the fuselage definition equations. User specified grid parameters govern the location and degree of grid concentration. A two-block volume grid about a configuration is calculated using the Control Point Form (CPF) technique. The interactive software, which runs on Silicon Graphics IRIS workstations, allows design parameters to be continuously varied and the resulting surface grid to be observed in real time. The batch software computes both the surface and volume grids and also computes the sensitivity of the output grid with respect to the input design parameters by applying the precompiler tool

  17. Computing Functions by Approximating the Input

    Science.gov (United States)

    Goldberg, Mayer

    2012-01-01

    In computing real-valued functions, it is ordinarily assumed that the input to the function is known, and it is the output that we need to approximate. In this work, we take the opposite approach: we show how to compute the values of some transcendental functions by approximating the input to these functions, and obtaining exact answers for their…

  18. Wave energy input into the Ekman layer

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This paper is concerned with the wave energy input into the Ekman layer, based on 3 observational facts that surface waves could significantly affect the profile of the Ekman layer. Under the assumption of constant vertical diffusivity, the analytical form of wave energy input into the Ekman layer is derived. Analysis of the energy balance shows that the energy input to the Ekman layer through the wind stress and the interaction of the Stokes-drift with planetary vorticity can be divided into two kinds. One is the wind energy input, and the other is the wave energy input which is dependent on wind speed, wave characteristics and the wind direction relative to the wave direction. Estimates of wave energy input show that wave energy input can be up to 10% in high-latitude and high-wind speed areas and higher than 20% in the Antarctic Circumpolar Current, compared with the wind energy input into the classical Ekman layer. Results of this paper are of significance to the study of wave-induced large scale effects.

  19. Analysis of the Denver Developmental Screening Test.

    Science.gov (United States)

    Sabin, James N.

    1978-01-01

    In an effort to validate the Denver Developmental Screening Test (DDST), the scores were compared with selected demographic, health history, and physical examination variables of migrant and seasonal farmworkers' preschool children in Colorado. (NQ)

  20. The range fraction: an applied method to characterize regional groundwater responses to climate inputs.

    Science.gov (United States)

    Leising, Joseph F; Lutz, Alexandra

    2014-12-01

    An important component of ongoing water-resource investigations in the eastern Great Basin, USA, has been to ascertain the impact of future predicted climate change on groundwater availability. As a first step in that analysis, it was hypothesized that potentiometric fluctuations at certain wells would reflect annual-scale precipitation variation. Potentiometric behavior at a well depends on local hydrologic conditions, well construction, and human activities, in addition to natural recharge and regional water levels. Moreover, measurement data are limited for many wells. After preliminarily screening, a large body of well and climate station data, short-term potentiometric responses to annual-scale climate inputs, were identified at 18 wells using a simple visualization methodology developed during the study. For water levels displaying multi-annual trends, the signals were measured as deviations from a linear trendline. Groundwater responses lagged precipitation signals by less than 1 year to as much as 3 years, with most wells showing at most a 1- to 2-year delay. Response amplitude was variable and strongly depended on the hydrologic setting of each well.

  1. Atmospheric Nitrogen input to the Kattegat

    DEFF Research Database (Denmark)

    Asman, W.A.H.; Hertel, O.; Berkowicz, R.

    1995-01-01

    An overview is given of the processes involved in the atmospheric deposition of nitrogen compounds. These processes are incorporated in an atmospheric transport model that is used to calculate the nitrogen input to the Kattegat, the sea area between Denmark and Sweden. The model results show...... that the total atmospheric nitrogen input to the Kattegat is approximately 960 kg N km(-2) yr(-1). The nitrogen input to the Kattegat is dominated by the wet depositions of NHx (42%) and NOy (30%). The contribution from the dry deposition of NHx is 17% and that of the dry deposition of NOy is 11......%. The contribution of the atmospheric input of nitrogen to the Kattegat is about 30% of the total input including the net transport from other sea areas, runoff etc....

  2. Input impedance characteristics of microstrip structures

    Directory of Open Access Journals (Sweden)

    A. I. Nazarko

    2015-06-01

    Full Text Available Introduction. Electromagnetic crystals (EC and EC-inhomogeneities are one of the main directions of microstrip devices development. In the article the input impedance characteristics of EC- and traditional microstrip inhomogeneities and filter based on EC-inhomogeneities are investigated. Transmission coefficient characteristics. Transmission coefficient characteristics of low impedance EC- and traditional inhomogeneities are considered. Characteristics are calculated in the software package Microwave Studio. It is shown that the efficiency of EC-inhomogeneity is much higher. Input impedance characteristics of low impedance inhomogeneities. Dependences of input impedance active and reactive parts of EC- and traditional inhomogeneities are given. Dependences of the active part illustrate significant low impedance transformation of nominal impedance. The conditions of impedance matching of structure and input medium are set. Input impedance characteristics of high impedance inhomogeneities. Input impedance characteristics of high impedance EC- and traditional inhomogeneities are considered. It was shown that the band of transformation by high impedance inhomogeneities is much narrower than one by low impedance inhomogeneities. Characteristics of the reflection coefficient of inhomogeneities are presented. Input impedance characteristics of narrowband filter. The structure of narrowband filter based on the scheme of Fabry-Perot resonator is presented. The structure of the filter is fulfilled by high impedance EC-inhomogeneities as a reflectors. Experimental and theoretical amplitude-frequency characteristics of the filter are presented. Input impedance characteristics of the filter are shown. Conclusions. Input impedance characteristics of the structure allow to analyse its wave properties, especially resonant. EC-inhomogeneity compared with traditional microstrip provide substantially more significant transformation of the the input impedance.

  3. A linearized input-output representation of flexible multibody systems for control synthesis

    NARCIS (Netherlands)

    Jonker, Jan B.; Aarts, Ronald G.K.M.; van Dijk, Johannes

    2009-01-01

    In this paper, a linearized input–output representation of flexible multibody systems is proposed in which an arbitrary combination of positions, velocities, accelerations, and forces can be taken as input variables and as output variables. The formulation is based on a nonlinear finite element

  4. Environmental Screening Assessment of Perchlorate Replacements

    Science.gov (United States)

    2007-08-01

    nitramido)dinitroethylene AP Ammonium perchlorate CAS Chemical Abstract Services DNNC 1,3,5,5-tetranitrohexahydropyrimidine EPI Estimation Program...can be created and pasted into the input screen or obtained from a linked file of Chemical Abstract Services (CAS) numbers. The EPI Suite Interface

  5. Integrate-and-fire vs Poisson models of LGN input to V1 cortex: noisier inputs reduce orientation selectivity.

    Science.gov (United States)

    Lin, I-Chun; Xing, Dajun; Shapley, Robert

    2012-12-01

    One of the reasons the visual cortex has attracted the interest of computational neuroscience is that it has well-defined inputs. The lateral geniculate nucleus (LGN) of the thalamus is the source of visual signals to the primary visual cortex (V1). Most large-scale cortical network models approximate the spike trains of LGN neurons as simple Poisson point processes. However, many studies have shown that neurons in the early visual pathway are capable of spiking with high temporal precision and their discharges are not Poisson-like. To gain an understanding of how response variability in the LGN influences the behavior of V1, we study response properties of model V1 neurons that receive purely feedforward inputs from LGN cells modeled either as noisy leaky integrate-and-fire (NLIF) neurons or as inhomogeneous Poisson processes. We first demonstrate that the NLIF model is capable of reproducing many experimentally observed statistical properties of LGN neurons. Then we show that a V1 model in which the LGN input to a V1 neuron is modeled as a group of NLIF neurons produces higher orientation selectivity than the one with Poisson LGN input. The second result implies that statistical characteristics of LGN spike trains are important for V1's function. We conclude that physiologically motivated models of V1 need to include more realistic LGN spike trains that are less noisy than inhomogeneous Poisson processes.

  6. Mathematical Models of the Sinusoidal Screen Family

    Directory of Open Access Journals (Sweden)

    Tajana Koren

    2011-06-01

    Full Text Available In this paper we will define a family of sinusoidal screening elements and explore the possibilities of their application in graphic arts, securities printing and design solutions in photography and typography editing. For this purpose mathematical expressions of sinusoidal families were converted into a Postscript language. The introduction of a random variable results in a countless number of various mutations which cannot be repeated without knowing the programming code itself. The use of the family of screens in protection of securities is thus of great importance. Other possible application of modulated sinusoidal screens is related to the large format color printing. This paper will test the application of sinusoidal screens in vector graphics, pixel graphics and typography. The development of parameters in the sinusoidal screen element algorithms gives new forms defined within screening cells with strict requirements of coverage implementation. Individual solutions include stochastic algorithms, as well as the autonomy of screening forms in regard to multicolor printing channels.

  7. Measuring Psychosocial Variables in Patients With (Sub) Acute Low Back Pain Complaints, at Risk for Chronicity A Validation Study of the Acute Low Back Pain Screening Questionnaire-Dutch Language Version

    NARCIS (Netherlands)

    Heneweer, Hans; van Woudenberg, Nienke J.; van Genderen, Frank; Vanhees, Luc; Wittink, Harriet

    2010-01-01

    Study Design. A validation study of the Acute Low Back Pain Screening Questionnaire Dutch Language Version (ALBPSQ-DLV). Objective. To determine internal consistency, construct and convergent validity of the ALBPSQ-DLV in a population of patients with (sub) acute low back pain (LBP) referred to prim

  8. An Avionics Touch Screen based Control Display Concept

    NARCIS (Netherlands)

    Mertens, M.; Damveld, H.J.; Borst, C.

    2012-01-01

    In many cockpits, control display units (CDUs) are vital input and information devices. In order to improve the usability of these devices, Barco, in cooperation with TU-Delft, created a touch screen control unit (TSCU), consisting of a high-quality multi-touch screen. The unit fits in the standard

  9. The cumulative risk of false-positive screening results across screening centres in the Norwegian Breast Cancer Screening Program

    Energy Technology Data Exchange (ETDEWEB)

    Roman, M., E-mail: Marta.Roman@kreftregisteret.no [Cancer Registry of Norway, Oslo (Norway); Department of Women and Children’s Health, Oslo University Hospital, Oslo (Norway); Skaane, P., E-mail: PERSK@ous-hf.no [Department of Radiology, Oslo University Hospital Ullevaal, University of Oslo, Oslo (Norway); Hofvind, S., E-mail: Solveig.Hofvind@kreftregisteret.no [Cancer Registry of Norway, Oslo (Norway); Oslo and Akershus University College of Applied Sciences, Faculty of Health Science, Oslo (Norway)

    2014-09-15

    Highlights: • We found variation in early performance measures across screening centres. • Radiologists’ performance may play a key role in the variability. • Potential to improve the effectiveness of breast cancer screening programs. • Continuous surveillance of screening centres and radiologists is essential. - Abstract: Background: Recall for assessment in mammographic screening entails an inevitable number of false-positive screening results. This study aimed to investigate the variation in the cumulative risk of a false positive screening result and the positive predictive value across the screening centres in the Norwegian Breast Cancer Screening Program. Methods: We studied 618,636 women aged 50–69 years who underwent 2,090,575 screening exams (1996–2010. Recall rate, positive predictive value, rate of screen-detected cancer, and the cumulative risk of a false positive screening result, without and with invasive procedures across the screening centres were calculated. Generalized linear models were used to estimate the probability of a false positive screening result and to compute the cumulative false-positive risk for up to ten biennial screening examinations. Results: The cumulative risk of a false-positive screening exam varied from 10.7% (95% CI: 9.4–12.0%) to 41.5% (95% CI: 34.1–48.9%) across screening centres, with a highest to lowest ratio of 3.9 (95% CI: 3.7–4.0). The highest to lowest ratio for the cumulative risk of undergoing an invasive procedure with a benign outcome was 4.3 (95% CI: 4.0–4.6). The positive predictive value of recall varied between 12.0% (95% CI: 11.0–12.9%) and 19.9% (95% CI: 18.3–21.5%), with a highest to lowest ratio of 1.7 (95% CI: 1.5–1.9). Conclusions: A substantial variation in the performance measures across the screening centres in the Norwegian Breast Cancer Screening Program was identified, despite of similar administration, procedures, and quality assurance requirements. Differences in the

  10. Numeric Input Relations for Relational Learning with Applications to Community Structure Analysis

    DEFF Research Database (Denmark)

    Jiang, Jiuchuan; Jaeger, Manfred

    2015-01-01

    distribution is defined by the model from numerical input variables that are only used for conditioning the distribution of discrete response variables. We show how numerical input relations can very easily be used in the Relational Bayesian Network framework, and that existing inference and learning methods......Most work in the area of statistical relational learning (SRL) is focussed on discrete data, even though a few approaches for hybrid SRL models have been proposed that combine numerical and discrete variables. In this paper we distinguish numerical random variables for which a probability...... need only minor adjustments to be applied in this generalized setting. The resulting framework provides natural relational extensions of classical probabilistic models for categorical data. We demonstrate the usefulness of RBN models with numeric input relations by several examples. In particular, we...

  11. Quantitative amyloid imaging using image-derived arterial input function.

    Directory of Open Access Journals (Sweden)

    Yi Su

    Full Text Available Amyloid PET imaging is an indispensable tool widely used in the investigation, diagnosis and monitoring of Alzheimer's disease (AD. Currently, a reference region based approach is used as the mainstream quantification technique for amyloid imaging. This approach assumes the reference region is amyloid free and has the same tracer influx and washout kinetics as the regions of interest. However, this assumption may not always be valid. The goal of this work is to evaluate an amyloid imaging quantification technique that uses arterial region of interest as the reference to avoid potential bias caused by specific binding in the reference region. 21 participants, age 58 and up, underwent Pittsburgh compound B (PiB PET imaging and MR imaging including a time-of-flight (TOF MR angiography (MRA scan and a structural scan. FreeSurfer based regional analysis was performed to quantify PiB PET data. Arterial input function was estimated based on coregistered TOF MRA using a modeling based technique. Regional distribution volume (VT was calculated using Logan graphical analysis with estimated arterial input function. Kinetic modeling was also performed using the estimated arterial input function as a way to evaluate PiB binding (DVRkinetic without a reference region. As a comparison, Logan graphical analysis was also performed with cerebellar cortex as reference to obtain DVRREF. Excellent agreement was observed between the two distribution volume ratio measurements (r>0.89, ICC>0.80. The estimated cerebellum VT was in line with literature reported values and the variability of cerebellum VT in the control group was comparable to reported variability using arterial sampling data. This study suggests that image-based arterial input function is a viable approach to quantify amyloid imaging data, without the need of arterial sampling or a reference region. This technique can be a valuable tool for amyloid imaging, particularly in population where reference

  12. Quantitative amyloid imaging using image-derived arterial input function.

    Science.gov (United States)

    Su, Yi; Blazey, Tyler M; Snyder, Abraham Z; Raichle, Marcus E; Hornbeck, Russ C; Aldea, Patricia; Morris, John C; Benzinger, Tammie L S

    2015-01-01

    Amyloid PET imaging is an indispensable tool widely used in the investigation, diagnosis and monitoring of Alzheimer's disease (AD). Currently, a reference region based approach is used as the mainstream quantification technique for amyloid imaging. This approach assumes the reference region is amyloid free and has the same tracer influx and washout kinetics as the regions of interest. However, this assumption may not always be valid. The goal of this work is to evaluate an amyloid imaging quantification technique that uses arterial region of interest as the reference to avoid potential bias caused by specific binding in the reference region. 21 participants, age 58 and up, underwent Pittsburgh compound B (PiB) PET imaging and MR imaging including a time-of-flight (TOF) MR angiography (MRA) scan and a structural scan. FreeSurfer based regional analysis was performed to quantify PiB PET data. Arterial input function was estimated based on coregistered TOF MRA using a modeling based technique. Regional distribution volume (VT) was calculated using Logan graphical analysis with estimated arterial input function. Kinetic modeling was also performed using the estimated arterial input function as a way to evaluate PiB binding (DVRkinetic) without a reference region. As a comparison, Logan graphical analysis was also performed with cerebellar cortex as reference to obtain DVRREF. Excellent agreement was observed between the two distribution volume ratio measurements (r>0.89, ICC>0.80). The estimated cerebellum VT was in line with literature reported values and the variability of cerebellum VT in the control group was comparable to reported variability using arterial sampling data. This study suggests that image-based arterial input function is a viable approach to quantify amyloid imaging data, without the need of arterial sampling or a reference region. This technique can be a valuable tool for amyloid imaging, particularly in population where reference normalization may

  13. What influences children's conceptualizations of language input?

    Science.gov (United States)

    Plante, Elena; Vance, Rebecca; Moody, Amanda; Gerken, LouAnn

    2013-10-01

    Children learning language conceptualize the nature of input they receive in ways that allow them to understand and construct utterances they have never heard before. This study was designed to illuminate the types of information children with and without specific language impairment (SLI) focus on to develop their conceptualizations and whether they can rapidly shift their initial conceptualizations if provided with additional input. In 2 studies, preschool children with and without SLI were exposed to an artificial language, the characteristics of which allowed for various types of conceptualizations about its fundamental properties. After being familiarized with the language, children were asked to judge test strings that conformed to the input in 1 of 4 different ways. All children preferred test items that reflected a narrow conceptualization of the input (i.e., items most like those heard during familiarization). Children showed a strong preference for phonology as a defining property of the artificial language. Restructuring the input to the child could induce them to track word order information as well. Children tend toward narrow conceptualizations of language input, but the nature of their conceptualizations can be influenced by the nature of the input they receive.

  14. Sensitivity analysis of a sound absorption model with correlated inputs

    Science.gov (United States)

    Chai, W.; Christen, J.-L.; Zine, A.-M.; Ichchou, M.

    2017-04-01

    Sound absorption in porous media is a complex phenomenon, which is usually addressed with homogenized models, depending on macroscopic parameters. Since these parameters emerge from the structure at microscopic scale, they may be correlated. This paper deals with sensitivity analysis methods of a sound absorption model with correlated inputs. Specifically, the Johnson-Champoux-Allard model (JCA) is chosen as the objective model with correlation effects generated by a secondary micro-macro semi-empirical model. To deal with this case, a relatively new sensitivity analysis method Fourier Amplitude Sensitivity Test with Correlation design (FASTC), based on Iman's transform, is taken into application. This method requires a priori information such as variables' marginal distribution functions and their correlation matrix. The results are compared to the Correlation Ratio Method (CRM) for reference and validation. The distribution of the macroscopic variables arising from the microstructure, as well as their correlation matrix are studied. Finally the results of tests shows that the correlation has a very important impact on the results of sensitivity analysis. Assessment of correlation strength among input variables on the sensitivity analysis is also achieved.

  15. Debye screening

    Science.gov (United States)

    Brydges, David C.; Federbush, Paul

    1980-10-01

    The existence and exponential clustering of correlation functions for a classical coulomb system at low density or high temperature are proven using methods from constructive quantum field theory, the sine gordon transformation and the Glimm, Jaffe, Spencer expansion about mean field theory. This is a vindication of a belief of long standing among physicists, known as Debye screening. That is, because of special properties of the coulomb potential, the configurations of significant probability are those in which the long range parts of r -1 are mostly cancelled, leaving an effective exponentially decaying potential acting between charge clouds. This paper generalizes a previous paper of one of the authors in which these results were obtained for a special lattice system. The present treatment covers the continuous mechanics situation, with essentially arbitrary short range forces and charge species. Charge symmetry is not assumed.

  16. Scaling of global input-output networks

    Science.gov (United States)

    Liang, Sai; Qi, Zhengling; Qu, Shen; Zhu, Ji; Chiu, Anthony S. F.; Jia, Xiaoping; Xu, Ming

    2016-06-01

    Examining scaling patterns of networks can help understand how structural features relate to the behavior of the networks. Input-output networks consist of industries as nodes and inter-industrial exchanges of products as links. Previous studies consider limited measures for node strengths and link weights, and also ignore the impact of dataset choice. We consider a comprehensive set of indicators in this study that are important in economic analysis, and also examine the impact of dataset choice, by studying input-output networks in individual countries and the entire world. Results show that Burr, Log-Logistic, Log-normal, and Weibull distributions can better describe scaling patterns of global input-output networks. We also find that dataset choice has limited impacts on the observed scaling patterns. Our findings can help examine the quality of economic statistics, estimate missing data in economic statistics, and identify key nodes and links in input-output networks to support economic policymaking.

  17. Input data to run Landis-II

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The data are input data files to run the forest simulation model Landis-II for Isle Royale National Park. Files include: a) Initial_Comm, which includes the location...

  18. Existence conditions for unknown input functional observers

    Science.gov (United States)

    Fernando, T.; MacDougall, S.; Sreeram, V.; Trinh, H.

    2013-01-01

    This article presents necessary and sufficient conditions for the existence and design of an unknown input Functional observer. The existence of the observer can be verified by computing a nullspace of a known matrix and testing some matrix rank conditions. The existence of the observer does not require the satisfaction of the observer matching condition (i.e. Equation (16) in Hou and Muller 1992, 'Design of Observers for Linear Systems with Unknown Inputs', IEEE Transactions on Automatic Control, 37, 871-875), is not limited to estimating scalar functionals and allows for arbitrary pole placement. The proposed observer always exists when a state observer exists for the unknown input system, and furthermore, the proposed observer can exist even in some instances when an unknown input state observer does not exist.

  19. Combined LTP and LTD of modulatory inputs controls neuronal processing of primary sensory inputs.

    Science.gov (United States)

    Doiron, Brent; Zhao, Yanjun; Tzounopoulos, Thanos

    2011-07-20

    A hallmark of brain organization is the integration of primary and modulatory pathways by principal neurons. However, the pathway interactions that shape primary input processing remain unknown. We investigated this problem in mouse dorsal cochlear nucleus (DCN) where principal cells integrate primary, auditory nerve input with modulatory, parallel fiber input. Using a combined experimental and computational approach, we show that combined LTP and LTD of parallel fiber inputs to DCN principal cells and interneurons, respectively, broaden the time window within which synaptic inputs summate. Enhanced summation depolarizes the resting membrane potential and thus lowers the response threshold to auditory nerve inputs. Combined LTP and LTD, by preserving the variance of membrane potential fluctuations and the membrane time constant, fixes response gain and spike latency as threshold is lowered. Our data reveal a novel mechanism mediating adaptive and concomitant homeostatic regulation of distinct features of neuronal processing of sensory inputs.

  20. Inadequacies of TPR and Krashen's Input Hypothesis

    Institute of Scientific and Technical Information of China (English)

    Meng Meng; LI Laifa

    2008-01-01

    In this paper,the rationale of TPR and the Input Hypothesis of Krashen which justifies practices of TPR are reviewed and criticized in the light of evidence from teachers'observation of a long-term TPR project.It is argued that the effectiveness of TPR is compromised by its inadequate attention to the complexity of classroom interactions and children's cognition.The Input Hypothesis is believed that it oversimplified the cognitive dynamics of language learning.

  1. Land Scale, Input-Output and Income

    Institute of Scientific and Technical Information of China (English)

    Mengzhi; DENG

    2013-01-01

    Based on the investigation of production, inputs and income of tobacco farmers in 337 families in 10 counties of which the specialty is tobacco in Henan Province in 2010, the differences in the production, inputs and income were discussed. Results suggested that in terms of land yield rate and tobacco growers income, the suitable proportion of land for tobacco production in Henan Province is from 0.33 to 0.67 hm2.

  2. Neural Networks with Complex and Quaternion Inputs

    OpenAIRE

    Rishiyur, Adityan

    2006-01-01

    This article investigates Kak neural networks, which can be instantaneously trained, for complex and quaternion inputs. The performance of the basic algorithm has been analyzed and shown how it provides a plausible model of human perception and understanding of images. The motivation for studying quaternion inputs is their use in representing spatial rotations that find applications in computer graphics, robotics, global navigation, computer vision and the spatial orientation of instruments. ...

  3. Significance of input correlations in striatal function.

    Directory of Open Access Journals (Sweden)

    Man Yi Yim

    2011-11-01

    Full Text Available The striatum is the main input station of the basal ganglia and is strongly associated with motor and cognitive functions. Anatomical evidence suggests that individual striatal neurons are unlikely to share their inputs from the cortex. Using a biologically realistic large-scale network model of striatum and cortico-striatal projections, we provide a functional interpretation of the special anatomical structure of these projections. Specifically, we show that weak pairwise correlation within the pool of inputs to individual striatal neurons enhances the saliency of signal representation in the striatum. By contrast, correlations among the input pools of different striatal neurons render the signal representation less distinct from background activity. We suggest that for the network architecture of the striatum, there is a preferred cortico-striatal input configuration for optimal signal representation. It is further enhanced by the low-rate asynchronous background activity in striatum, supported by the balance between feedforward and feedback inhibitions in the striatal network. Thus, an appropriate combination of rates and correlations in the striatal input sets the stage for action selection presumably implemented in the basal ganglia.

  4. Plasticity of the cis-regulatory input function of a gene.

    Directory of Open Access Journals (Sweden)

    Avraham E Mayo

    2006-04-01

    Full Text Available The transcription rate of a gene is often controlled by several regulators that bind specific sites in the gene's cis-regulatory region. The combined effect of these regulators is described by a cis-regulatory input function. What determines the form of an input function, and how variable is it with respect to mutations? To address this, we employ the well-characterized lac operon of Escherichia coli, which has an elaborate input function, intermediate between Boolean AND-gate and OR-gate logic. We mapped in detail the input function of 12 variants of the lac promoter, each with different point mutations in the regulator binding sites, by means of accurate expression measurements from living cells. We find that even a few mutations can significantly change the input function, resulting in functions that resemble Pure AND gates, OR gates, or single-input switches. Other types of gates were not found. The variant input functions can be described in a unified manner by a mathematical model. The model also lets us predict which functions cannot be reached by point mutations. The input function that we studied thus appears to be plastic, in the sense that many of the mutations do not ruin the regulation completely but rather result in new ways to integrate the inputs.

  5. Back propagation artificial neural network for community Alzheimer's disease screening in China

    Institute of Scientific and Technical Information of China (English)

    Jun Tang; Lei Wu; Helang Huang; Jiang Feng; Yefeng Yuan; Yueping Zhou; Peng Huang; Yan Xu; Chao Yu

    2013-01-01

    Alzheimer's disease patients diagnosed with the Chinese Classification of Mental Disorders diagnostic criteria were selected from the community through on-site sampling. Levels of macro and trace elements were measured in blood samples using an atomic absorption method, and neurotransmitters were measured using a radioimmunoassay method. SPSS 13.0 was used to establish a database, and a back propagation artificial neural network for Alzheimer's disease prediction was simulated using Clementine 12.0 software. With scores of activities of daily living, creatinine, 5-hydroxytryptamine, age, dopamine and aluminum as input variables, the results revealed that the area under the curve in our back propagation artificial neural network was 0.929 accuracy was 92.50%. The findings indicated that the results of back propagation artificial neural network established based on the above six variables were satisfactory for screening and diagnosis of Alzheimer's disease in patients selected from the community.

  6. A designed screening study with prespecified combinations of factor settings

    Energy Technology Data Exchange (ETDEWEB)

    Anderson-cook, Christine M [Los Alamos National Laboratory; Robinson, Timothy J [U. WYOMING

    2009-01-01

    In many applications, the experimenter has limited options about what factor combinations can be chosen for a designed study. Consider a screening study for a production process involving five input factors whose levels have been previously established. The goal of the study is to understand the effect of each factor on the response, a variable that is expensive to measure and results in destruction of the part. From an inventory of available parts with known factor values, we wish to identify a best collection of factor combinations with which to estimate the factor effects. Though the observational nature of the study cannot establish a causal relationship involving the response and the factors, the study can increase understanding of the underlying process. The study can also help determine where investment should be made to control input factors during production that will maximally influence the response. Because the factor combinations are observational, the chosen model matrix will be nonorthogonal and will not allow independent estimation of factor effects. In this manuscript we borrow principles from design of experiments to suggest an 'optimal' selection of factor combinations. Specifically, we consider precision of model parameter estimates, the issue of replication, and abilities to detect lack of fit and to estimate two-factor interactions. Through an example, we present strategies for selecting a subset of factor combinations that simultaneously balance multiple objectives, conduct a limited sensitivity analysis, and provide practical guidance for implementing our techniques across a variety of quality engineering disciplines.

  7. High concentrations of divalent cations isolate monosynaptic inputs from local circuits in the auditory midbrain

    Directory of Open Access Journals (Sweden)

    Shobhana eSivaramakrishnan

    2013-10-01

    Full Text Available Hierarchical processing of sensory information occurs at multiple levels between the peripheral and central pathway. Different extents of convergence and divergence in top down and bottom up projections makes it difficult to separate the various components activated by a sensory input. In particular, hierarchical processing at sub-cortical levels is little understood. Here we have developed a method to isolate extrinsic inputs to the inferior colliculus (IC, a nucleus in the midbrain region of the auditory system, with extensive ascending and descending convergence. By applying a high concentration of divalent cations (HiDi locally within the IC, we isolate a HiDi-sensitive from a HiDi-insensitive component of responses evoked by afferent input in brain slices and in vivo during a sound stimulus. Our results suggest that the HiDi sensitive component is a monosynaptic input to the IC, while the HiDi-insensitive component is a local polysynaptic circuit. Monosynaptic inputs have short latencies, rapid rise times and underlie first spike latencies. Local inputs have variable delays and evoke long-lasting excitation. In vivo, local circuits have variable onset times and temporal profiles. Our results suggest that high concentrations of divalent cations should prove to be a widely useful method of isolating extrinsic monosynaptic inputs from local circuits in vivo.

  8. Mental Health Screening Center

    Science.gov (United States)

    ... Releases & Announcements Public Service Announcements Partnering with DBSA Mental Health Screening Center These online screening tools are not ... you have any concerns, see your doctor or mental health professional. Depression This screening form was developed from ...

  9. Lung Cancer Screening

    Science.gov (United States)

    ... Treatment Lung Cancer Prevention Lung Cancer Screening Research Lung Cancer Screening (PDQ®)–Patient Version What is screening? Go ... These are called diagnostic tests . General Information About Lung Cancer Key Points Lung cancer is a disease in ...

  10. Skin Cancer Screening

    Science.gov (United States)

    ... Genetics of Skin Cancer Skin Cancer Screening Research Skin Cancer Screening (PDQ®)–Patient Version What is screening? ... These are called diagnostic tests . General Information About Skin Cancer Key Points Skin cancer is a disease ...

  11. Testicular Cancer Screening

    Science.gov (United States)

    ... Health Professional Testicular Cancer Treatment Testicular Cancer Screening Testicular Cancer Screening (PDQ®)–Patient Version What is screening? Go ... These are called diagnostic tests . General Information About Testicular Cancer Key Points Testicular cancer is a disease in ...

  12. Efficient biological process characterization by definitive-screening designs: the formaldehyde treatment of a therapeutic protein as a case study.

    Science.gov (United States)

    Erler, Axel; de Mas, Nuria; Ramsey, Philip; Henderson, Grant

    2013-03-01

    As part of the process-characterization campaign of a candidate vaccine product, a recently developed class of three-level designs-definitive-screening designs-was employed to select a quadratic model that describes the effect of six input process parameters, including protein concentration, formaldehyde-to-protein ratio, lysine concentration, reaction duration, pH, and reaction temperature, on a formylation protein-crosslinking reaction. This design requires only 17 experimental runs. The resulting model was then used to simulate 10,000 runs that account for the variability in the inputs expected on manufacturing scale. The extent of protein polymerization was predicted to be within specifications for all simulated runs, demonstrating the robustness of the unit operation for subsequent process validation and future commercial manufacturing.

  13. Analysis of Input and Output of China’s Agriculture Based on Canonical Correlation

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    I select effective irrigated area, consumption of agricultural chemical fertilizer, electricity consumed in rural areas, and total power of agricultural machinery as input variables of China’s agriculture; I select grain, bean, tobacco, oil-bearing crop and fruit as output variables of China’s agriculture. By using the data of China Statistical Yearbook in 2010, based on the analysis method of canonical correlation, I conduct research on the input and output of China’s agriculture. The results show that consumption of chemical fertilizer has the biggest impact on the agricultural output of China, followed by the input of total power of agricultural machinery; the canonical variable of agricultural output of China is mainly impacted by grain, oil-bearing crop and fruit; in terms of the selected variables, the output increase of grain, oil-bearing crop and fruit in China arises from the input increase of agricultural chemical fertilizer and machinery, and there is high-degree correlation between the two. According to the conclusions, the policy suggestions are put forward as follows: gradually decrease consumption of chemical fertilizer; increase the use of modern agricultural machinery; increase agricultural irrigation input.

  14. DC SQUIDS with planar input coils

    Energy Technology Data Exchange (ETDEWEB)

    Pegrum, C.M.; Donaldson, G.B.; Hutson, D.; Tugwell, A.

    1985-03-01

    We describe the key parts of our recent work to develop a planar thin-film DC SQUID with a closely-coupled spiral input coil. Our aim has been to make a device that is superior to present RF SQUID sensors in terms of sensitivity and long-term reliability. To be compatible with an RF SQUID the inductance of the input coils must be relatively large, typically 2..mu..H, and the input noise current in the white noise region should be below 10pA Hz /SUP -1/2/ . A low level of 1/f noise is also necessary for many applications and should be achieved without the use of complex noisecancelling circuitry. Our devices meet these criteria. We include a description of work on window and edge junction fabrication using ion beam cleaning, thermal oxidation and RF plasma processing.

  15. Nonlinearities with Non-Gaussian Inputs.

    Science.gov (United States)

    1978-03-01

    possessing a spectral density function . a constant. Then Jet arc tan [G(t)J be the input. By Theorem 3 this input is not bandlimited; and if The rando...such that the absolute ,,~~ovalue of any point in the spectrum is less than N. If the Gaussian process X(t) possesses a H ~ ) spectral density function (i.e...Gaussian process and th. series ii convergent pointvise as veil X(t ) possesses a spectral density function . as in an sense (51. Let z~( ) and g2

  16. Input/Output Subroutine Library Program

    Science.gov (United States)

    Collier, James B.

    1988-01-01

    Efficient, easy-to-use program moved easily to different computers. Purpose of NAVIO, Input/Output Subroutine Library, provides input/output package of software for FORTRAN programs that is portable, efficient, and easy to use. Implemented as hierarchy of libraries. At bottom is very small library containing only non-portable routines called "I/O Kernel." Design makes NAVIO easy to move from one computer to another, by simply changing kernel. NAVIO appropriate for software system of almost any size wherein different programs communicate through files.

  17. Network dynamics for optimal compressive-sensing input-signal recovery.

    Science.gov (United States)

    Barranca, Victor J; Kovačič, Gregor; Zhou, Douglas; Cai, David

    2014-10-01

    By using compressive sensing (CS) theory, a broad class of static signals can be reconstructed through a sequence of very few measurements in the framework of a linear system. For networks with nonlinear and time-evolving dynamics, is it similarly possible to recover an unknown input signal from only a small number of network output measurements? We address this question for pulse-coupled networks and investigate the network dynamics necessary for successful input signal recovery. Determining the specific network characteristics that correspond to a minimal input reconstruction error, we are able to achieve high-quality signal reconstructions with few measurements of network output. Using various measures to characterize dynamical properties of network output, we determine that networks with highly variable and aperiodic output can successfully encode network input information with high fidelity and achieve the most accurate CS input reconstructions. For time-varying inputs, we also find that high-quality reconstructions are achievable by measuring network output over a relatively short time window. Even when network inputs change with time, the same optimal choice of network characteristics and corresponding dynamics apply as in the case of static inputs.

  18. Input-output relations in biological systems: measurement, information and the Hill equation.

    Science.gov (United States)

    Frank, Steven A

    2013-01-01

    Biological systems produce outputs in response to variable inputs. Input-output relations tend to follow a few regular patterns. For example, many chemical processes follow the S-shaped Hill equation relation between input concentrations and output concentrations. That Hill equation pattern contradicts the fundamental Michaelis-Menten theory of enzyme kinetics. I use the discrepancy between the expected Michaelis-Menten process of enzyme kinetics and the widely observed Hill equation pattern of biological systems to explore the general properties of biological input-output relations. I start with the various processes that could explain the discrepancy between basic chemistry and biological pattern. I then expand the analysis to consider broader aspects that shape biological input-output relations. Key aspects include the input-output processing by component subsystems and how those components combine to determine the system's overall input-output relations. That aggregate structure often imposes strong regularity on underlying disorder. Aggregation imposes order by dissipating information as it flows through the components of a system. The dissipation of information may be evaluated by the analysis of measurement and precision, explaining why certain common scaling patterns arise so frequently in input-output relations. I discuss how aggregation, measurement and scale provide a framework for understanding the relations between pattern and process. The regularity imposed by those broader structural aspects sets the contours of variation in biology. Thus, biological design will also tend to follow those contours. Natural selection may act primarily to modulate system properties within those broad constraints.

  19. Ashtekar variables

    Science.gov (United States)

    Ashtekar, Abhay

    2015-05-01

    In the spirit of Scholarpedia, this invited article is addressed to students and younger researchers. It provides the motivation and background material, a summary of the main physical ideas, mathematical structures and results, and an outline of applications of the connection variables for general relativity. These variables underlie both the canonical/Hamiltonian and the spinfoam/path integral approaches in loop quantum gravity.

  20. Prenatal screening and genetics

    DEFF Research Database (Denmark)

    Alderson, P; Aro, A R; Dragonas, T

    2001-01-01

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we...... examine definitions of the relevant concepts in order to illustrate this point. The concepts are i) prenatal, ii) genetic screening, iii) screening, scanning and testing, iv) maternal and foetal tests, v) test techniques and vi) genetic conditions. So far, prenatal screening has little connection...... with precisely defined genetics. There are benefits but also disadvantages in overstating current links between them in the term genetic screening. Policy making and professional and public understandings about screening could be clarified if the distinct meanings of prenatal screening and genetic screening were...

  1. An Analysis of Input Hypothesis in English Teaching

    Institute of Scientific and Technical Information of China (English)

    赖菲菲

    2016-01-01

    Input plays a significant role in the process of foreign language teaching and learning. One of the most important studies about input is Krashen's Input Hypothesis, which emphasizes the importance of comprehensive input in foreign language teaching and learning. This paper aims to study the significance of Input Hypothesis and its application to English teaching.

  2. Effect of dynamic keyboard and word-prediction systems on text input speed in persons with functional tetraplegia.

    Science.gov (United States)

    Pouplin, Samuel; Robertson, Johanna; Antoine, Jean-Yves; Blanchet, Antoine; Kahloun, Jean Loup; Volle, Philippe; Bouteille, Justine; Lofaso, Frédéric; Bensmail, Djamel

    2014-01-01

    Information technology plays a very important role in society. People with disabilities are often limited by slow text input speed despite the use of assistive devices. This study aimed to evaluate the effect of a dynamic on-screen keyboard (Custom Virtual Keyboard) and a word-prediction system (Sibylle) on text input speed in participants with functional tetraplegia. Ten participants tested four modes at home (static on-screen keyboard with and without word prediction and dynamic on-screen keyboard with and without word prediction) for 1 mo before choosing one mode and then using it for another month. Initial mean text input speed was around 23 characters per minute with the static keyboard and 12 characters per minute with the dynamic keyboard. The results showed that the dynamic keyboard reduced text input speed by 37% compared with the standard keyboard and that the addition of word prediction had no effect on text input speed. We suggest that current forms of dynamic keyboards and word prediction may not be suitable for increasing text input speed, particularly for subjects who use pointing devices. Future studies should evaluate the optimal ergonomic design of dynamic keyboards and the number and position of words that should be predicted.

  3. Declarative Semantics of Input Consuming Logic Programs

    NARCIS (Netherlands)

    Bossi, Annalisa; Cocco, Nicoletta; Etalle, Sandro; Rossi, Sabina; Bruynooghe, Maurice; Lau, Kung-Kia

    2004-01-01

    Most logic programming languages actually provide some kind of dynamic scheduling to increase the expressive power and to control execution. Input consuming derivations have been introduced to describe dynamic scheduling while abstracting from the technical details. We review and compare the differe

  4. Input and age effects: Quo vadis?

    NARCIS (Netherlands)

    Weerman, F.

    2014-01-01

    The article discusses the important role played input in language acquisition. Topics include the difficulty in obtaining the difference between groups and languages, the visibility of the success of children concerning inflection in their knowledge, and the description of lexical mistake for monoli

  5. Selecting training inputs via greedy rank covering

    Energy Technology Data Exchange (ETDEWEB)

    Buchsbaum, A.L.; Santen, J.P.H. van [AT& T Bell Laboratories, Murray Hill, NJ (United States)

    1996-12-31

    We present a general method for selecting a small set of training inputs, the observations of which will suffice to estimate the parameters of a given linear model. We exemplify the algorithm in terms of predicting segmental duration of phonetic-segment feature vectors in a text-to-speech synthesizer, but the algorithm will work for any linear model and its associated domain.

  6. The Contrast Theory of negative input.

    Science.gov (United States)

    Saxton, M

    1997-02-01

    Beliefs about whether or not children receive corrective input for grammatical errors depend crucially on how one defines the concept of correction. Arguably, previous conceptualizations do not provide a viable basis for empirical research (Gold, 1967; Brown & Hanlon, 1970; Hirsh-Pasek, Treiman & Schneiderman, 1984). Within the Contrast Theory of negative input, an alternative definition of negative evidence is offered, based on the idea that the unique discourse structure created in the juxtaposition of child error and adult correct form can reveal to the child the contrast, or conflict, between the two forms, and hence provide a basis for rejecting the erroneous form. A within-subjects experimental design was implemented for 36 children (mean age 5;0), in order to compare the immediate effects of negative evidence with those of positive input, on the acquisition of six novel irregular past tense forms. Children reproduced the correct irregular model more often, and persisted with fewer errors, following negative evidence rather than positive input.

  7. Capital Power:From Input to Output

    Institute of Scientific and Technical Information of China (English)

    You Wanlong; Alice

    2009-01-01

    @@ After thirty yeas "going out" of China overseas investment,we learn from our failed lessons and also successful experience.Chinese enterprises are now standing at a new starting point of "going out".China is transforming from "capital input power" to "capital output power".

  8. Treatments of Precipitation Inputs to Hydrologic Models

    Science.gov (United States)

    Hydrological models are used to assess many water resources problems from agricultural use and water quality to engineering issues. The success of these models are dependent on correct parameterization; the most sensitive being the rainfall input time series. These records can come from land-based ...

  9. Input and Intake in Language Acquisition

    Science.gov (United States)

    Gagliardi, Ann C.

    2012-01-01

    This dissertation presents an approach for a productive way forward in the study of language acquisition, sealing the rift between claims of an innate linguistic hypothesis space and powerful domain general statistical inference. This approach breaks language acquisition into its component parts, distinguishing the input in the environment from…

  10. Input and Intake in Language Acquisition

    Science.gov (United States)

    Gagliardi, Ann C.

    2012-01-01

    This dissertation presents an approach for a productive way forward in the study of language acquisition, sealing the rift between claims of an innate linguistic hypothesis space and powerful domain general statistical inference. This approach breaks language acquisition into its component parts, distinguishing the input in the environment from…

  11. Declarative Semantics of Input Consuming Logic Programs

    NARCIS (Netherlands)

    Bossi, Annalisa; Cocco, Nicoletta; Etalle, Sandro; Rossi, Sabina; Bruynooghe, Maurice; Lau, Kung-Kia

    2004-01-01

    Most logic programming languages actually provide some kind of dynamic scheduling to increase the expressive power and to control execution. Input consuming derivations have been introduced to describe dynamic scheduling while abstracting from the technical details. We review and compare the differe

  12. Programmable Input for Nanomagnetic Logic Devices

    Directory of Open Access Journals (Sweden)

    Schmitt-Landsiedel D.

    2013-01-01

    Full Text Available A programmable magnetic input, based on the magnetic interaction of a soft and hard magnetic layer is presented for the first time. Therefore, a single-domain Co/Pt nanomagnet is placed on top of one end of a permalloy bar, separated by a thin dielectric layer. The permalloy bar of the introduced input structure is magnetized by weak easy-axis in-plane fields. Acting like a ’magnetic amplifier’, the generated fringing fields of the permalloy pole are strong enough to control the magnetization of the superimposed Co/Pt nanomagnets, which have high crystalline perpendicular magnetic anisotropy. This magnetostatic interaction results in a shift of the hysteresis curve of the Co/Pt nanomagnet, measured by magneto-optical Kerr microscopy. The Co/Pt nanomagnet is fixed by the fringing field of the permalloy and thereby not affected by the magnetic power clock of the Nanomagnetic Logic system. MFM measurements verify the functionality of the programmable magnetic input structure. The fringing fields are extracted from micromagnetic simulations and are in good agreement with experimental results. The introduced input structure enables switching the logic functionality of the majority gate from NAND to NOR during runtime, offering programmable Nanomagnetic Logic.

  13. Leaders’ receptivity to subordinates’ creative input: the role of achievement goals and composition of creative input

    NARCIS (Netherlands)

    Sijbom, R.B.L.; Janssen, O.; van Yperen, N.W.

    2015-01-01

    We identified leaders’ achievement goals and composition of creative input as important factors that can clarify when and why leaders are receptive to, and supportive of, subordinates’ creative input. As hypothesized, in two experimental studies, we found that relative to mastery goal leaders, perfo

  14. Leaders’ receptivity to subordinates’ creative input: the role of achievement goals and composition of creative input

    NARCIS (Netherlands)

    Sijbom, R.B.L.; Janssen, O.; van Yperen, N.W.

    2015-01-01

    We identified leaders’ achievement goals and composition of creative input as important factors that can clarify when and why leaders are receptive to, and supportive of, subordinates’ creative input. As hypothesized, in two experimental studies, we found that relative to mastery goal leaders, perfo

  15. Leaders’ receptivity to subordinates’ creative input: the role of achievement goals and composition of creative input

    NARCIS (Netherlands)

    R.B.L. Sijbom; O. Janssen; N.W. van Yperen

    2014-01-01

    We identified leaders’ achievement goals and composition of creative input as important factors that can clarify when and why leaders are receptive to, and supportive of, subordinates’ creative input. As hypothesized, in two experimental studies, we found that relative to mastery goal leaders, perfo

  16. Leaders’ receptivity to subordinates’ creative input: the role of achievement goals and composition of creative input

    NARCIS (Netherlands)

    Sijbom, R.B.L.; Janssen, O.; van Yperen, N.W.

    2015-01-01

    We identified leaders’ achievement goals and composition of creative input as important factors that can clarify when and why leaders are receptive to, and supportive of, subordinates’ creative input. As hypothesized, in two experimental studies, we found that relative to mastery goal leaders,

  17. Stomach (Gastric) Cancer Screening

    Science.gov (United States)

    ... Gastric Cancer Treatment Stomach Cancer Prevention Stomach Cancer Screening Research Stomach (Gastric) Cancer Screening (PDQ®)–Patient Version What is ... from the . There is no standard or routine screening test for stomach cancer. Several types of screening tests have been ...

  18. Prenatal screening and genetics

    NARCIS (Netherlands)

    Alderson, P.; Aro, A.R.; Dragonas, T.; Ettorre, E.; Hemminki, E.; Jalinoja, P.; Santalahti, P.; Tijmstra, T.

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we

  19. Prenatal screening and genetics

    NARCIS (Netherlands)

    Alderson, P.; Aro, A.R.; Dragonas, T.; Ettorre, E.; Hemminki, E.; Jalinoja, P.; Santalahti, P.; Tijmstra, T.

    2001-01-01

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we exami

  20. Prenatal screening and genetics

    DEFF Research Database (Denmark)

    Alderson, P; Aro, A R; Dragonas, T

    2001-01-01

    Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we ex...

  1. Numeric Input Relations for Relational Learning with Applications to Community Structure Analysis

    DEFF Research Database (Denmark)

    Jiang, Jiuchuan; Jaeger, Manfred

    2015-01-01

    Most work in the area of statistical relational learning (SRL) is focussed on discrete data, even though a few approaches for hybrid SRL models have been proposed that combine numerical and discrete variables. In this paper we distinguish numerical random variables for which a probability...... distribution is defined by the model from numerical input variables that are only used for conditioning the distribution of discrete response variables. We show how numerical input relations can very easily be used in the Relational Bayesian Network framework, and that existing inference and learning methods...... use the augmented RBN framework to define probabilistic models for multi-relational (social) networks in which the probability of a link between two nodes depends on numeric latent feature vectors associated with the nodes. A generic learning procedure can be used to obtain a maximum-likelihood fit...

  2. Screening for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Lindholt, J S; Juul, Svend; Henneberg, E W;

    1997-01-01

    rupture. Ultrasonographic screening for AAA takes 10 minutes per scan, and the sensitivity and specificity are high. Ultrasonographic screening for AAA is a reliable, safe and inexpensive method for screening, and screening for AAA is discussed worldwide. One point four percent of deaths among men from 65...... on uncertain assumptions concerning prevalence, incidence and risk of rupture. Therefore a randomized trial screening of 65-73 year old males is taking place in the County of Viborg in Denmark. Udgivelsesdato: 1997-Mar-24...

  3. Screening for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Lindholt, Jes Sanddal; Juul, Søren; Henneberg, E W;

    1997-01-01

    rupture. Ultrasonographic screening for AAA takes 10 minutes per scan, and the sensitivity and specificity are high. Ultrasonographic screening for AAA is a reliable, safe and inexpensive method for screening, and screening for AAA is discussed worldwide. One point four percent of deaths among men from 65...... on uncertain assumptions concerning prevalence, incidence and risk of rupture. Therefore a randomized trial screening of 65-73 year old males is taking place in the County of Viborg in Denmark....

  4. Effectiveness during ball screens in elite basketball games.

    Science.gov (United States)

    Gómez, Miguel-Ángel; Battaglia, Otavio; Lorenzo, Alberto; Lorenzo, Jorge; Jiménez, Sergio; Sampaio, Jaime

    2015-01-01

    Ball screens are one of the most frequently used tactical behaviour in elite basketball games. The aim of the present study was to identify their predictors of success related to time, space, players, and tasks performed. The sample was composed of 818 ball screens corresponding to 20 close games (mean differences in score of 3.1 ± 0.8 points) randomly selected from the playoff games of the Spanish Basketball League (2008-2011). Classification tree analysis (CHAID) was used to analyse which variable or combination of variables, better predicts effectiveness during ball screens. The main results allowed identifying interactions with dribbler actions after the screen and the orientation of the screen on the ball. The results showed no interaction with game quarter and quarter minute temporal-related variables in both analyses. The present findings allow improving coaches' strategic plans that involve selecting the most appropriate offensive approach when performing ball screens.

  5. Colonoscopy Screening Information Preferences Among Urban Hispanics

    OpenAIRE

    Ellison, Jennie; Jandorf, Lina; DuHamel, Katherine

    2011-01-01

    Existing disparities are evident in colorectal cancer (CRC) screening. We sought to assess preferred sources of colonoscopy screening information among Hispanics in East Harlem, NY. Face-to-face interviews were conducted among average-risk for CRC, non-symptomatic Hispanics in community-based sites and health clinics. SPSS 16 analysis explored the relationships between sociodemographic and health care variables and preferred sources of colonoscopy information for 395 participants. The top fou...

  6. Sharply notch cylindrical tension specimen for screening plane-strain fracture toughness. I - Influence of fundamental testing variables on notch strength. II Applications in aluminum alloy quality assurance of fracture toughness

    Science.gov (United States)

    Jones, M. H.; Bubsey, R. T.; Brown, W. F., Jr.; Bucci, R. J.; Collis, S. F.; Kohm, R. F.; Kaufman, J. G.

    1977-01-01

    A description is presented of studies which have been conducted to establish an improved technology base for a use of the sharply notched cylindrical specimen in quality assurance tests of aluminum alloy products. The results are presented of an investigation of fundamental variables associated with specimen preparation and testing, taking into account the influence of the notch root radius, the eccentricity of loading, the specimen diameter, and the notch depth on the sharp notch strength. Attention is given to the statistical procedures which are necessary to establish correlations between the sharp notch strength and the plane-strain fracture toughness for high-strength aluminum alloys.

  7. Risks of Esophageal Cancer Screening

    Science.gov (United States)

    ... Esophageal Cancer Prevention Esophageal Cancer Screening Research Esophageal Cancer Screening (PDQ®)–Patient Version What is screening? Go to ... the esophagus and the stomach). Being overweight . Esophageal Cancer Screening Key Points Tests are used to screen for ...

  8. Do efficiency scores depend on input mix?

    DEFF Research Database (Denmark)

    Asmild, Mette; Hougaard, Jens Leth; Kronborg, Dorte

    2013-01-01

    In this paper we examine the possibility of using the standard Kruskal-Wallis (KW) rank test in order to evaluate whether the distribution of efficiency scores resulting from Data Envelopment Analysis (DEA) is independent of the input (or output) mix of the observations. Since the DEA frontier...... is estimated, many standard assumptions for evaluating the KW test statistic are violated. Therefore, we propose to explore its statistical properties by the use of simulation studies. The simulations are performed conditional on the observed input mixes. The method, unlike existing approaches...... the assumption of mix independence is rejected the implication is that it, for example, is impossible to determine whether machine intensive project are more or less efficient than labor intensive projects....

  9. Multimodal interfaces with voice and gesture input

    Energy Technology Data Exchange (ETDEWEB)

    Milota, A.D.; Blattner, M.M.

    1995-07-20

    The modalities of speech and gesture have different strengths and weaknesses, but combined they create synergy where each modality corrects the weaknesses of the other. We believe that a multimodal system such a one interwining speech and gesture must start from a different foundation than ones which are based solely on pen input. In order to provide a basis for the design of a speech and gesture system, we have examined the research in other disciplines such as anthropology and linguistics. The result of this investigation was a taxonomy that gave us material for the incorporation of gestures whose meanings are largely transparent to the users. This study describes the taxonomy and gives examples of applications to pen input systems.

  10. Controlling Synfire Chain by Inhibitory Synaptic Input

    Science.gov (United States)

    Shinozaki, Takashi; Câteau, Hideyuki; Urakubo, Hidetoshi; Okada, Masato

    2007-04-01

    The propagation of highly synchronous firings across neuronal networks, called the synfire chain, has been actively studied both theoretically and experimentally. The temporal accuracy and remarkable stability of the propagation have been repeatedly examined in previous studies. However, for such a mode of signal transduction to play a major role in processing information in the brain, the propagation should also be controlled dynamically and flexibly. Here, we show that inhibitory but not excitatory input can bidirectionally modulate the propagation, i.e., enhance or suppress the synchronous firings depending on the timing of the input. Our simulations based on the Hodgkin-Huxley neuron model demonstrate this bidirectional modulation and suggest that it should be achieved with any biologically inspired modeling. Our finding may help describe a concrete scenario of how multiple synfire chains lying in a neuronal network are appropriately controlled to perform significant information processing.

  11. Virtual input device with diffractive optical element

    Science.gov (United States)

    Wu, Ching Chin; Chu, Chang Sheng

    2005-02-01

    As a portable device, such as PDA and cell phone, a small size build in virtual input device is more convenient for complex input demand. A few years ago, a creative idea called 'virtual keyboard' is announced, but up to now there's still no mass production method for this idea. In this paper we'll show the whole procedure of making a virtual keyboard. First of all is the HOE (Holographic Optical Element) design of keyboard image which yields a fan angle about 30 degrees, and then use the electron forming method to copy this pattern in high precision. And finally we can product this element by inject molding. With an adaptive lens design we can get a well correct keyboard image in distortion and a wilder fan angle about 70 degrees. With a batter alignment of HOE pattern lithography, we"re sure to get higher diffraction efficiency.

  12. Neuroprosthetics and the science of patient input.

    Science.gov (United States)

    Benz, Heather L; Civillico, Eugene F

    2017-01-01

    Safe and effective neuroprosthetic systems are of great interest to both DARPA and CDRH, due to their innovative nature and their potential to aid severely disabled populations. By expanding what is possible in human-device interaction, these devices introduce new potential benefits and risks. Therefore patient input, which is increasingly important in weighing benefits and risks, is particularly relevant for this class of devices. FDA has been a significant contributor to an ongoing stakeholder conversation about the inclusion of the patient voice, working collaboratively to create a new framework for a patient-centered approach to medical device development. This framework is evolving through open dialogue with researcher and patient communities, investment in the science of patient input, and policymaking that is responsive to patient-centered data throughout the total product life cycle. In this commentary, we will discuss recent developments in patient-centered benefit-risk assessment and their relevance to the development of neural prosthetic systems.

  13. Model based optimization of EMC input filters

    Energy Technology Data Exchange (ETDEWEB)

    Raggl, K; Kolar, J. W. [Swiss Federal Institute of Technology, Power Electronic Systems Laboratory, Zuerich (Switzerland); Nussbaumer, T. [Levitronix GmbH, Zuerich (Switzerland)

    2008-07-01

    Input filters of power converters for compliance with regulatory electromagnetic compatibility (EMC) standards are often over-dimensioned in practice due to a non-optimal selection of number of filter stages and/or the lack of solid volumetric models of the inductor cores. This paper presents a systematic filter design approach based on a specific filter attenuation requirement and volumetric component parameters. It is shown that a minimal volume can be found for a certain optimal number of filter stages for both the differential mode (DM) and common mode (CM) filter. The considerations are carried out exemplarily for an EMC input filter of a single phase power converter for the power levels of 100 W, 300 W, and 500 W. (author)

  14. Design of a 6 DOF Input Device in Telerobotics and Virtual Reality

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The principle of a 6 DOF (degrees of freedom) input device using ultrasonic distance measurement is presented in this paper. The system employs the method of measuring the time of flight. In addition, some techniques, including automatic gain control, self-adaptive variable threshold and temperature compensation, are also used to improve precision. Then, the positions and orientations of the input device can be calculated by the method of spatial analytic geometry. Meanwhile, commands from the 3-D input device are detected and carried out. The validity and precision of the input device are verified by the experiment in a robot system. The proposed device not only can be used for end-effector position and orientation measurement in telerobotics, but also can be an interactive device in virtual reality systems, such as helmet tracking, viewpoint navigation and object manipulation.

  15. Mechanical energy input to the world oceans due to atmospheric loading

    Institute of Scientific and Technical Information of China (English)

    WANG Wei; QIAN Chengchun; HUANG Ruixin

    2006-01-01

    Mechanical energy input to the oceans is one of the most important factors controlling the oceanic general circulation. The atmosphere transports mechanical energy to the oceans primarily through wind stress, plus changes of the sea level pressure (the so-called atmospheric loading). The rate of mechanical energy transfer into the ocean due to atmospheric loading is calculated, based on TOPEX/POSEIDON data over ten-year period (1993-2002). The rate of total energy input for the world oceans is estimated at 0.04TW (1TW=1012Watt), and most of this energy input is concentrated in the Southern Oceans and the Storm Tracks in the Northern Hemisphere. This energy input varied greatly with time, and the amplitude of the interannual variability over the past ten years is about 15%.

  16. Solar wind-magnetosphere energy input functions

    Energy Technology Data Exchange (ETDEWEB)

    Bargatze, L.F.; McPherron, R.L.; Baker, D.N.

    1985-01-01

    A new formula for the solar wind-magnetosphere energy input parameter, P/sub i/, is sought by applying the constraints imposed by dimensional analysis. Applying these constraints yields a general equation for P/sub i/ which is equal to rho V/sup 3/l/sub CF//sup 2/F(M/sub A/,theta) where, rho V/sup 3/ is the solar wind kinetic energy density and l/sub CF//sup 2/ is the scale size of the magnetosphere's effective energy ''collection'' region. The function F which depends on M/sub A/, the Alfven Mach number, and on theta, the interplanetary magnetic field clock angle is included in the general equation for P/sub i/ in order to model the magnetohydrodynamic processes which are responsible for solar wind-magnetosphere energy transfer. By assuming the form of the function F, it is possible to further constrain the formula for P/sub i/. This is accomplished by using solar wind data, geomagnetic activity indices, and simple statistical methods. It is found that P/sub i/ is proportional to (rho V/sup 2/)/sup 1/6/VBG(theta) where, rho V/sup 2/ is the solar wind dynamic pressure and VBG(theta) is a rectified version of the solar wind motional electric field. Furthermore, it is found that G(theta), the gating function which modulates the energy input to the magnetosphere, is well represented by a ''leaky'' rectifier function such as sin/sup 4/(theta/2). This function allows for enhanced energy input when the interplanetary magnetic field is oriented southward. This function also allows for some energy input when the interplanetary magnetic field is oriented northward. 9 refs., 4 figs.

  17. Sensory Synergy as Environmental Input Integration

    Directory of Open Access Journals (Sweden)

    Fady eAlnajjar

    2015-01-01

    Full Text Available The development of a method to feed proper environmental inputs back to the central nervous system (CNS remains one of the challenges in achieving natural movement when part of the body is replaced with an artificial device. Muscle synergies are widely accepted as a biologically plausible interpretation of the neural dynamics between the CNS and the muscular system. Yet the sensorineural dynamics of environmental feedback to the CNS has not been investigated in detail. In this study, we address this issue by exploring the concept of sensory synergy. In contrast to muscle synergy, we hypothesize that sensory synergy plays an essential role in integrating the overall environmental inputs to provide low-dimensional information to the CNS. We assume that sensor synergy and muscle synergy communicate using these low-dimensional signals. To examine our hypothesis, we conducted posture control experiments involving lateral disturbance with 9 healthy participants. Proprioceptive information represented by the changes on muscle lengths were estimated by using the musculoskeletal model analysis software SIMM. Changes on muscles lengths were then used to compute sensory synergies. The experimental results indicate that the environmental inputs were translated into the two dimensional signals and used to move the upper limb to the desired position immediately after the lateral disturbance. Participants who showed high skill in posture control were found to be likely to have a strong correlation between sensory and muscle signaling as well as high coordination between the utilized sensory synergies. These results suggest the importance of integrating environmental inputs into suitable low-dimensional signals before providing them to the CNS. This mechanism should be essential when designing the prosthesis’ sensory system to make the controller simpler

  18. EMOWARS: INTERACTIVE GAME INPUT MENGGUNAKAN EKSPRESI WAJAH

    Directory of Open Access Journals (Sweden)

    Andry Chowanda

    2013-11-01

    opportunity for researchers in affective game with a more interactive game play as well as rich and complex story. Hopefully this will improve the user affective state and emotions in game. The results of this research imply that happy emotion obtains 78% of detection, meanwhile the anger emotion has the lowest detection of 44.4%. Moreover, users prefer mouse and FER (face expression recognition as the best input for this game.

  19. Cometary micrometeorites and input of prebiotic compounds

    OpenAIRE

    2014-01-01

    The apparition of life on the early Earth was probably favored by inputs of extraterrestrial matter brought by carbonaceous chondrite-like objects or cometary material. Interplanetary dust collected nowadays on Earth is related to carbonaceous chondrites and to cometary material. They contain in particular at least a few percent of organic matter, organic compounds (amino-acids, PAHs,…), hydrous silicates, and could have largely contributed to the budget of prebiotic matter on Earth, about 4 ...

  20. Emowars: Interactive Game Input Menggunakan Ekspresi Wajah

    Directory of Open Access Journals (Sweden)

    Andry Chowanda

    2013-12-01

    Full Text Available Research in the affective game has received attention from the research communities over this lustrum. As a crucial aspect of a game, emotions play an important role in user experience as well as to emphasize the user’s emotions state on game design. This will improve the user’s interactivity while they playing the game. This research aims to discuss and analyze whether emotions can replace traditional user game inputs (keyboard, mouse, and others. The methodology used in this research is divided into two main phases: game design and facial expression recognition. The results of this research indicate that users preferred to use a traditional input such as mouse. Moreover, user’s interactivities with game are still slightly low. However, this is a great opportunity for researchers in affective game with a more interactive game play as well as rich and complex story. Hopefully this will improve the user affective state and emotions in game. The results of this research imply that happy emotion obtains 78% of detection, meanwhile the anger emotion has the lowest detection of44.4%. Moreover, users prefer mouse and FER (face expression recognition as the best input for this game.

  1. Molecular structure input on the web

    Directory of Open Access Journals (Sweden)

    Ertl Peter

    2010-02-01

    Full Text Available Abstract A molecule editor, that is program for input and editing of molecules, is an indispensable part of every cheminformatics or molecular processing system. This review focuses on a special type of molecule editors, namely those that are used for molecule structure input on the web. Scientific computing is now moving more and more in the direction of web services and cloud computing, with servers scattered all around the Internet. Thus a web browser has become the universal scientific user interface, and a tool to edit molecules directly within the web browser is essential. The review covers a history of web-based structure input, starting with simple text entry boxes and early molecule editors based on clickable maps, before moving to the current situation dominated by Java applets. One typical example - the popular JME Molecule Editor - will be described in more detail. Modern Ajax server-side molecule editors are also presented. And finally, the possible future direction of web-based molecule editing, based on technologies like JavaScript and Flash, is discussed.

  2. Incorporating User Input in Template-Based Segmentation.

    Science.gov (United States)

    Vidal, Camille; Beggs, Dale; Younes, Laurent; Jain, Sanjay K; Jedynak, Bruno

    2011-01-01

    We present a simple and elegant method to incorporate user input in a template-based segmentation method for diseased organs. The user provides a partial segmentation of the organ of interest, which is used to guide the template towards its target. The user also highlights some elements of the background that should be excluded from the final segmentation. We derive by likelihood maximization a registration algorithm from a simple statistical image model in which the user labels are modeled as Bernoulli random variables. The resulting registration algorithm minimizes the sum of square differences between the binary template and the user labels, while preventing the template from shrinking, and penalizing for the inclusion of background elements into the final segmentation. We assess the performance of the proposed algorithm on synthetic images in which the amount of user annotation is controlled. We demonstrate our algorithm on the segmentation of the lungs of Mycobacterium tuberculosis infected mice from μCT images.

  3. Sparse polynomial surrogates for aerodynamic computations with random inputs

    CERN Document Server

    Savin, Eric; Peter, Jacques

    2015-01-01

    This paper deals with some of the methodologies used to construct polynomial surrogate models based on generalized polynomial chaos (gPC) expansions for applications to uncertainty quantification (UQ) in aerodynamic computations. A core ingredient in gPC expansions is the choice of a dedicated sampling strategy, so as to define the most significant scenarios to be considered for the construction of such metamodels. A desirable feature of the proposed rules shall be their ability to handle several random inputs simultaneously. Methods to identify the relative "importance" of those variables or uncertain data shall be ideally considered as well. The present work is more particularly dedicated to the development of sampling strategies based on sparsity principles. Sparse multi-dimensional cubature rules based on general one-dimensional Gauss-Jacobi-type quadratures are first addressed. These sets are non nested, but they are well adapted to the probability density functions with compact support for the random in...

  4. Complex variables

    CERN Document Server

    Fisher, Stephen D

    1999-01-01

    The most important topics in the theory and application of complex variables receive a thorough, coherent treatment in this introductory text. Intended for undergraduates or graduate students in science, mathematics, and engineering, this volume features hundreds of solved examples, exercises, and applications designed to foster a complete understanding of complex variables as well as an appreciation of their mathematical beauty and elegance. Prerequisites are minimal; a three-semester course in calculus will suffice to prepare students for discussions of these topics: the complex plane, basic

  5. The Importance of Input and Interaction in SLA

    Institute of Scientific and Technical Information of China (English)

    党春花

    2009-01-01

    As is known to us, input and interaction play the crucial roles in second language acquisition (SLA). Different linguistic schools have different explanations to input and interaction Behaviorist theories hold a view that input is composed of stimuli and response, putting more emphasis on the importance of input, while mentalist theories find input is a necessary condition to SLA, not a sufficient condition. At present, social interaction theories, which is one type of cognitive linguistics, suggests that besides input, interaction is also essential to language acquisition. Then, this essay will discuss how input and interaction result in SLA.

  6. 间歇性电源高渗透电网输电规划方案评价和筛选方法%Evaluation and Screening Method for Power Grid Planning Schemes Under High Penetration of Variable Generation

    Institute of Scientific and Technical Information of China (English)

    杨海涛; 吉平; 宋墩文; 陈西颖

    2014-01-01

    基于对间歇性电源高渗透条件下电网规划的特殊影响因素以及现有规划方法和工具局限性的讨论,提出了电网接纳间歇性电源的能力指标和计及电网连锁反应过程的安全风险指标等方案补充评价指标;提出了基于风电场经济上可接受的最小年发电量和电网安全性等因素判断电网接纳风电能力是否合适的方法;还提出了应用了多种辅助软件的适用于间歇性电源高渗透电网输电综合规划的流程、方案评价和筛选方法。研究结果表明,采用上述方法可在间歇性电源高渗透电网规划方案综合比较选择中计及电网事故过程等复杂特性,是评价和筛选此类电网的规划方案的有效途径。%Following a discussion of the specific influencing factors in the power grid planning under high penetration of variable generation and the limitations of existing methods and tools for the planning,the supplementary evaluation indices for the planning,such as the capability of accommodating intermittent generation sources and the security risk index taking into account the cascade process,are presented.Secondly,a method of j udging whether the capability of admitting intermittent generation sources is rational or not on the basis of acceptability in terms of economy of the least annual energy outputs of the generation sources and the security of the power grid is presented.Finally,a method of employing a number of assistant software to form,analyze,assess and select the planning schemes is presented.The complex characteristics such as the process of contingency can be taken into account in comprehensive comparison and selection of the power grid planning schemes under high penetration of variable generation by utilizing the above method.It is an effective channel through which to evaluate and choose such power grid planning schemes.

  7. Cone inputs to murine striate cortex

    Directory of Open Access Journals (Sweden)

    Gouras Peter

    2008-11-01

    Full Text Available Abstract Background We have recorded responses from single neurons in murine visual cortex to determine the effectiveness of the input from the two murine cone photoreceptor mechanisms and whether there is any unique selectivity for cone inputs at this higher region of the visual system that would support the possibility of colour vision in mice. Each eye was stimulated by diffuse light, either 370 (strong stimulus for the ultra-violet (UV cone opsin or 505 nm (exclusively stimulating the middle wavelength sensitive (M cone opsin, obtained from light emitting diodes (LEDs in the presence of a strong adapting light that suppressed the responses of rods. Results Single cells responded to these diffuse stimuli in all areas of striate cortex. Two types of responsive cells were encountered. One type (135/323 – 42% had little to no spontaneous activity and responded at either the on and/or the off phase of the light stimulus with a few impulses often of relatively large amplitude. A second type (166/323 – 51% had spontaneous activity and responded tonically to light stimuli with impulses often of small amplitude. Most of the cells responded similarly to both spectral stimuli. A few (18/323 – 6% responded strongly or exclusively to one or the other spectral stimulus and rarely in a spectrally opponent manner. Conclusion Most cells in murine striate cortex receive excitatory inputs from both UV- and M-cones. A small fraction shows either strong selectivity for one or the other cone mechanism and occasionally cone opponent responses. Cells that could underlie chromatic contrast detection are present but extremely rare in murine striate cortex.

  8. Hearing Loss: Screening Newborns

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Hearing Loss Screening Newborns Past Issues / Spring 2015 Table of ... of newborns in the U.S. are screened for hearing loss before they leave the hospital. Research improves the ...

  9. Cervical Cancer Screening

    Science.gov (United States)

    ... Cancer found early may be easier to treat. Cervical cancer screening is usually part of a woman's health ... may do more tests, such as a biopsy. Cervical cancer screening has risks. The results can sometimes be ...

  10. Screening for Cervical Cancer

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Cervical Cancer The U.S. Preventive Services Task Force (Task Force) has issued final recommendations on Screening for Cervical Cancer . These recommendations are for women ...

  11. Screening for Ovarian Cancer

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Ovarian Cancer The U.S. Preventive Services Task Force (Task Force) has issued a final recommendation on Screening for Ovarian Cancer . This recommendation is for ...

  12. Video Screen Capture Basics

    Science.gov (United States)

    Dunbar, Laura

    2014-01-01

    This article is an introduction to video screen capture. Basic information of two software programs, QuickTime for Mac and BlueBerry Flashback Express for PC, are also discussed. Practical applications for video screen capture are given.

  13. Prostate Cancer Screening

    Science.gov (United States)

    ... a man's bladder that produces fluid for semen. Cancer screening is looking for cancer before you have any ... as an ultrasound, MRI, or a biopsy. Prostate cancer screening has risks: Finding prostate cancer may not improve ...

  14. Alcohol Use Screening

    Science.gov (United States)

    ... Centers Diseases + Condition Centers Mental Health Medical Library Alcohol Use Screening (AUDIT-C) - Instructions The following questions ... this tool, there is also text-only version . Alcohol Use Screening (AUDIT-C) - Manual Instructions The following ...

  15. Endometrial Cancer Screening

    Science.gov (United States)

    ... Transvaginal ultrasound Endometrial sampling Tests are used to screen for different types of cancer. Some screening tests ... endometrium by inserting a brush, curette , or thin, flexible tube through the cervix and into the uterus. ...

  16. Screening for Glaucoma

    Science.gov (United States)

    Understanding Task Force Recommendations Screening for Glaucoma The U.S. Preventive Services Task Force (Task Force) has issued a final recommendation statement on Screening for Glaucoma . This final recommendation statement ...

  17. Comparison between Input Hypothesis and Interaction Hypothesis

    Institute of Scientific and Technical Information of China (English)

    李佳

    2012-01-01

      Krashen’s Input hypothesis and Long’s Interaction hypothesis are both valuable research results in the field of language acquisition and play a significant role in language teaching and learning instruction. Through comparing them, their similarities lie in same goal and basis, same focus on comprehension and same challenge the traditional teaching concept. While the differences lie in Different ways to make exposure comprehensible and different roles that learners play. It is meaningful to make the compari⁃son because the results can be valuable guidance and highlights for language teachers and learners to teach or acquire a new lan⁃guage more efficiently.

  18. LISTENING COMPREHENSION: MORE THAN JUST COMPREHENSIBLE INPUT

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    In the ten years since the publication of Krashen’s theory on second language acquisition (SLA), the role of comprehensible input (CI) in the learning/acquiring of a language has received considerable attention (Krashen, 1982, 1985; Ellis, 1991, 1992; Long, 1983, 1985). As a result of these studies researchers now agree on the following points. Exposure to a language does not lead to acquisition; the personal accounts of so many language learners who have spent many years in a country or who have listened to endless hours of radio and television without being able to understand or speak the language attest to this fact.

  19. Operational modal analysis with non stationnary inputs

    OpenAIRE

    Gouache, Thibault; Morlier, Joseph; Michon, Guilhem; Coulange, Baptiste

    2013-01-01

    Operational modal analysis (OMA) techniques enable the use of in-situ and uncontrolled vibrations to be used to lead modal analysis of structures. In reality operational vibrations are a combination of numerous excitations sources that are much more complex than a random white noise or a harmonic. Numerous OMA techniques exist like SSI, NExT, FDD and BSS. All these methods are based on the fundamental hypothesis that the input or force applied to the structure to be analyzed is a stationary w...

  20. TSM control of the delayed input system

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The paper proposed a terminal sliding mode control method for the delayed input system with uncertainties. Firstly, through the state transformation, the original system was transformed into the non-delayed controllable canonical form system. Then the paper designed a terminal sliding mode and terminal sliding control law with Lyapunov method for the transformed system. Through the method, the reaching time of the any initial state and the convergencing time to the equilibrium points are constrained in finite time. The simulation results show the validation of the method.

  1. Intelligent Graph Layout Using Many Users' Input.

    Science.gov (United States)

    Yuan, Xiaoru; Che, Limei; Hu, Yifan; Zhang, Xin

    2012-12-01

    In this paper, we propose a new strategy for graph drawing utilizing layouts of many sub-graphs supplied by a large group of people in a crowd sourcing manner. We developed an algorithm based on Laplacian constrained distance embedding to merge subgraphs submitted by different users, while attempting to maintain the topological information of the individual input layouts. To facilitate collection of layouts from many people, a light-weight interactive system has been designed to enable convenient dynamic viewing, modification and traversing between layouts. Compared with other existing graph layout algorithms, our approach can achieve more aesthetic and meaningful layouts with high user preference.

  2. Flexible input, dazzling output with IBM i

    CERN Document Server

    Victória-Pereira, Rafael

    2014-01-01

    Link your IBM i system to the modern business server world! This book presents easier and more flexible ways to get data into your IBM i system, along with rather surprising methods to export and present the vital business data it contains. You'll learn how to automate file transfers, seamlessly connect PC applications with your RPG programs, and much more. Input operations will become more flexible and user-proof, with self-correcting import processes and direct file transfers that require a minimum of user intervention. Also learn novel ways to present information: your DB2 data will look gr

  3. Input-output-controlled nonlinear equation solvers

    Science.gov (United States)

    Padovan, Joseph

    1988-01-01

    To upgrade the efficiency and stability of the successive substitution (SS) and Newton-Raphson (NR) schemes, the concept of input-output-controlled solvers (IOCS) is introduced. By employing the formal properties of the constrained version of the SS and NR schemes, the IOCS algorithm can handle indefiniteness of the system Jacobian, can maintain iterate monotonicity, and provide for separate control of load incrementation and iterate excursions, as well as having other features. To illustrate the algorithmic properties, the results for several benchmark examples are presented. These define the associated numerical efficiency and stability of the IOCS.

  4. Example of input-output analysis

    Science.gov (United States)

    1975-01-01

    The thirty sectors included in the ECASTAR energy input-output model were listed. Five of these belong to energy producing sectors, fifteen to manufacturing industries, two to residential and commercial sectors, and eight to service industries. The model is capable of tracing impacts of an action in three dimensions: dollars, BTU's of energy, and labor. Four conservation actions considered were listed and then discussed separately, dealing with the following areas: increase in fuel efficiency, reduction in fuel used by the transportation and warehousing group, manufacturing of smaller automobiles, and a communications/transportation trade-off.

  5. Input data to run Landis-II

    Science.gov (United States)

    DeJager, Nathan R.

    2017-01-01

    The data are input data files to run the forest simulation model Landis-II for Isle Royale National Park. Files include: a) Initial_Comm, which includes the location of each mapcode, b) Cohort_ages, which includes the ages for each tree species-cohort within each mapcode, c) Ecoregions, which consist of different regions of soils and climate, d) Ecoregion_codes, which define the ecoregions, and e) Species_Params, which link the potential establishment and growth rates for each species with each ecoregion.

  6. Culture Input in Foreign Language Teaching

    Institute of Scientific and Technical Information of China (English)

    胡晶

    2009-01-01

    Language and culture are highly interrelated, that is to say, language is not only the carrier of culture but it is also restricted by culture. Therefore, foreign language teaching aiming at cultivate students' intercultural communication should take culture differences into consideration. In this paper, the relationship between language and culture will be discussed. Then I will illustrate the importance of intercultural communication. Finally, according to the present situation of foreign language teaching in China, several strategies for cultural input in and out of class will be suggested.

  7. Approximate input physics for stellar modelling

    CERN Document Server

    Pols, O R; Eggleton, P P; Han, Z; Pols, O R; Tout, C A; Eggleton, P P; Han, Z

    1995-01-01

    We present a simple and efficient, yet reasonably accurate, equation of state, which at the moderately low temperatures and high densities found in the interiors of stars less massive than the Sun is substantially more accurate than its predecessor by Eggleton, Faulkner & Flannery. Along with the most recently available values in tabular form of opacities, neutrino loss rates, and nuclear reaction rates for a selection of the most important reactions, this provides a convenient package of input physics for stellar modelling. We briefly discuss a few results obtained with the updated stellar evolution code.

  8. A pilot study comparing mouse and mouse-emulating interface devices for graphic input.

    Science.gov (United States)

    Kanny, E M; Anson, D K

    1991-01-01

    Adaptive interface devices make it possible for individuals with physical disabilities to use microcomputers and thus perform many tasks that they would otherwise be unable to accomplish. Special equipment is available that purports to allow functional access to the computer for users with disabilities. As technology moves from purely keyboard applications to include graphic input, it will be necessary for assistive interface devices to support graphics as well as text entry. Headpointing systems that emulate the mouse in combination with on-screen keyboards are of particular interest to persons with severe physical impairment such as high level quadriplegia. Two such systems currently on the market are the HeadMaster and the Free Wheel. The authors have conducted a pilot study comparing graphic input speed using the mouse and two headpointing interface systems on the Macintosh computer. The study used a single subject design with six able-bodied subjects, to establish a baseline for comparison with persons with severe disabilities. Results of these preliminary data indicated that the HeadMaster was nearly as effective as the mouse and that it was superior to the Free Wheel for graphics input. This pilot study, however, demonstrated several experimental design problems that need to be addressed to make the study more robust. It also demonstrated the need to include the evaluation of text input so that the effectiveness of the interface devices with text and graphic input could be compared.

  9. The Hubble Catalog of Variables

    Science.gov (United States)

    Sokolovsky, K.; Bonanos, A.; Gavras, P.; Yang, M.; Hatzidimitriou, D.; Moretti, M. I.; Karampelas, A.; Bellas-Velidis, I.; Spetsieri, Z.; Pouliasis, E.; Georgantopoulos, I.; Charmandaris, V.; Tsinganos, K.; Laskaris, N.; Kakaletris, G.; Nota, A.; Lennon, D.; Arviset, C.; Whitmore, B.; Budavari, T.; Downes, R.; Lubow, S.; Rest, A.; Strolger, L.; White, R.

    2017-09-01

    We aim to construct an exceptionally deep (V ≲ 27) catalog of variable objects in selected Galactic and extragalactic fields visited multiple times by the Hubble Space Telescope (HST). While HST observations of some of these fields were searched for specific types of variables before (most notably, the extragalactic Cepheids), we attempt a systematic study of the population of variable objects of all types at the magnitude range not easily accessible with ground-based telescopes. The variability timescales that can be probed range from hours to years depending on how often a particular field has been visited. For source extraction and cross-matching of sources between visits we rely on the Hubble Source Catalog which includes 107 objects detected with WFPC2, ACS, and WFC3 HST instruments. The lightcurves extracted from the HSC are corrected for systematic effects by applying local zero-point corrections and are screened for bad measurements. For each lightcurve we compute variability indices sensitive to a broad range of variability types. The indices characterize the overall lightcurve scatter and smoothness. Candidate variables are selected as having variability index values significantly higher than expected for objects of similar brightness in the given set of observations. The Hubble Catalog of Variables will be released in 2018.

  10. The Hubble Catalog of Variables

    Directory of Open Access Journals (Sweden)

    Sokolovsky K.

    2017-01-01

    Full Text Available We aim to construct an exceptionally deep (V ≲ 27 catalog of variable objects in selected Galactic and extragalactic fields visited multiple times by the Hubble Space Telescope (HST. While HST observations of some of these fields were searched for specific types of variables before (most notably, the extragalactic Cepheids, we attempt a systematic study of the population of variable objects of all types at the magnitude range not easily accessible with ground-based telescopes. The variability timescales that can be probed range from hours to years depending on how often a particular field has been visited. For source extraction and cross-matching of sources between visits we rely on the Hubble Source Catalog which includes 107 objects detected with WFPC2, ACS, and WFC3 HST instruments. The lightcurves extracted from the HSC are corrected for systematic effects by applying local zero-point corrections and are screened for bad measurements. For each lightcurve we compute variability indices sensitive to a broad range of variability types. The indices characterize the overall lightcurve scatter and smoothness. Candidate variables are selected as having variability index values significantly higher than expected for objects of similar brightness in the given set of observations. The Hubble Catalog of Variables will be released in 2018.

  11. Colorectal cancer screening.

    Science.gov (United States)

    Burt, Randall W; Cannon, Jamie A; David, Donald S; Early, Dayna S; Ford, James M; Giardiello, Francis M; Halverson, Amy L; Hamilton, Stanley R; Hampel, Heather; Ismail, Mohammad K; Jasperson, Kory; Klapman, Jason B; Lazenby, Audrey J; Lynch, Patrick M; Mayer, Robert J; Ness, Reid M; Provenzale, Dawn; Rao, M Sambasiva; Shike, Moshe; Steinbach, Gideon; Terdiman, Jonathan P; Weinberg, David; Dwyer, Mary; Freedman-Cass, Deborah

    2013-12-01

    Mortality from colorectal cancer can be reduced by early diagnosis and by cancer prevention through polypectomy. These NCCN Guidelines for Colorectal Cancer Screening describe various colorectal screening modalities and recommended screening schedules for patients at average or increased risk of developing colorectal cancer. In addition, the guidelines provide recommendations for the management of patients with high-risk colorectal cancer syndromes, including Lynch syndrome. Screening approaches for Lynch syndrome are also described.

  12. Screening for Lung Cancer

    Science.gov (United States)

    Mazzone, Peter J.; Naidich, David P.; Bach, Peter B.

    2013-01-01

    Background: Lung cancer is by far the major cause of cancer deaths largely because in the majority of patients it is at an advanced stage at the time it is discovered, when curative treatment is no longer feasible. This article examines the data regarding the ability of screening to decrease the number of lung cancer deaths. Methods: A systematic review was conducted of controlled studies that address the effectiveness of methods of screening for lung cancer. Results: Several large randomized controlled trials (RCTs), including a recent one, have demonstrated that screening for lung cancer using a chest radiograph does not reduce the number of deaths from lung cancer. One large RCT involving low-dose CT (LDCT) screening demonstrated a significant reduction in lung cancer deaths, with few harms to individuals at elevated risk when done in the context of a structured program of selection, screening, evaluation, and management of the relatively high number of benign abnormalities. Whether other RCTs involving LDCT screening are consistent is unclear because data are limited or not yet mature. Conclusions: Screening is a complex interplay of selection (a population with sufficient risk and few serious comorbidities), the value of the screening test, the interval between screening tests, the availability of effective treatment, the risk of complications or harms as a result of screening, and the degree with which the screened individuals comply with screening and treatment recommendations. Screening with LDCT of appropriate individuals in the context of a structured process is associated with a significant reduction in the number of lung cancer deaths in the screened population. Given the complex interplay of factors inherent in screening, many questions remain on how to effectively implement screening on a broader scale. PMID:23649455

  13. The Effects of Pre Modified Input, Interactionally Modified Input, and Modified Output on EFL Learners' Comprehension of New Vocabularies

    Science.gov (United States)

    Maleki, Zinat; Pazhakh, AbdolReza

    2012-01-01

    The present study was an attempt to investigate the effects of premodified input, interactionally modified input and modified output on 80 EFL learners' comprehension of new words. The subjects were randomly assigned into four groups of pre modified input, interactionally modified input, modified output and unmodified (control) groups. Each group…

  14. Selection of key ambient particulate variables for epidemiological studies - applying cluster and heatmap analyses as tools for data reduction.

    Science.gov (United States)

    Gu, Jianwei; Pitz, Mike; Breitner, Susanne; Birmili, Wolfram; von Klot, Stephanie; Schneider, Alexandra; Soentgen, Jens; Reller, Armin; Peters, Annette; Cyrys, Josef

    2012-10-01

    The success of epidemiological studies depends on the use of appropriate exposure variables. The purpose of this study is to extract a relatively small selection of variables characterizing ambient particulate matter from a large measurement data set. The original data set comprised a total of 96 particulate matter variables that have been continuously measured since 2004 at an urban background aerosol monitoring site in the city of Augsburg, Germany. Many of the original variables were derived from measured particle size distribution (PSD) across the particle diameter range 3 nm to 10 μm, including size-segregated particle number concentration, particle length concentration, particle surface concentration and particle mass concentration. The data set was complemented by integral aerosol variables. These variables were measured by independent instruments, including black carbon, sulfate, particle active surface concentration and particle length concentration. It is obvious that such a large number of measured variables cannot be used in health effect analyses simultaneously. The aim of this study is a pre-screening and a selection of the key variables that will be used as input in forthcoming epidemiological studies. In this study, we present two methods of parameter selection and apply them to data from a two-year period from 2007 to 2008. We used the agglomerative hierarchical cluster method to find groups of similar variables. In total, we selected 15 key variables from 9 clusters which are recommended for epidemiological analyses. We also applied a two-dimensional visualization technique called "heatmap" analysis to the Spearman correlation matrix. 12 key variables were selected using this method. Moreover, the positive matrix factorization (PMF) method was applied to the PSD data to characterize the possible particle sources. Correlations between the variables and PMF factors were used to interpret the meaning of the cluster and the heatmap analyses

  15. Between Stage and Screen

    NARCIS (Netherlands)

    Tornqvist, Egil

    1996-01-01

    Ingmar Bergman is worldwide known as a film and stage director. Yet no-one has attempted to compare his stage and screen activities. In Between stage and screen Egil Tornqvist examines formal and thematical correspondences and differences between a number of Bergman's stage, screen, and radio produc

  16. Screen time and children

    Science.gov (United States)

    ... obesity ) Screen time increases your child's risk of obesity because: Sitting and watching a screen is time that is not spent being physically active. TV commercials and other screen ads can lead to unhealthy food choices . Most of the time, the foods in ads ...

  17. Screen Practice in Curating

    DEFF Research Database (Denmark)

    Toft, Tanya Søndergaard

    2014-01-01

    During the past one and a half decade, a curatorial orientation towards "screen practice" has expanded the moving image and digital art into the public domain, exploring alternative artistic uses of the screen. The emergence of urban LED screens in the late 1990s provided a new venue that allowed...

  18. Principles of Cancer Screening.

    Science.gov (United States)

    Pinsky, Paul F

    2015-10-01

    Cancer screening has long been an important component of the struggle to reduce the burden of morbidity and mortality from cancer. Notwithstanding this history, many aspects of cancer screening remain poorly understood. This article presents a summary of basic principles of cancer screening that are relevant for researchers, clinicians, and public health officials alike. Published by Elsevier Inc.

  19. Breast awareness and screening.

    Science.gov (United States)

    Harmer, Victoria

    Breast cancer is the most commonly diagnosed cancer in the UK. Breast awareness and screening, along with better treatment, can significantly improve outcomes, and more women than ever are now surviving the disease. This article discusses breast awareness and screening, symptoms and risk factors for breast cancer, and how nurses can raise breast awareness and screening uptake.

  20. Interacting with notebook input devices: an analysis of motor performance and users' expertise.

    Science.gov (United States)

    Sutter, Christine; Ziefle, Martina

    2005-01-01

    In the present study the usability of two different types of notebook input devices was examined. The independent variables were input device (touchpad vs. mini-joystick) and user expertise (expert vs. novice state). There were 30 participants, of whom 15 were touchpad experts and the other 15 were mini-joystick experts. The experimental tasks were a point-click task (Experiment 1) and a point-drag-drop task (Experiment 2). Dependent variables were the time and accuracy of cursor control. To assess carryover effects, we had the participants complete both experiments, using not only the input device for which they were experts but also the device for which they were novices. Results showed the touchpad performance to be clearly superior to mini-joystick performance. Overall, experts showed better performance than did novices. The significant interaction of input device and expertise showed that the use of an unknown device is difficult, but only for touchpad experts, who were remarkably slower and less accurate when using a mini-joystick. Actual and potential applications of this research include an evaluation of current notebook input devices. The outcomes allow ergonomic guidelines to be derived for optimized usage and design of the mini-joystick and touchpad devices.

  1. Cometary micrometeorites and input of prebiotic compounds

    Directory of Open Access Journals (Sweden)

    Engrand C.

    2014-02-01

    Full Text Available The apparition of life on the early Earth was probably favored by inputs of extraterrestrial matter brought by carbonaceous chondrite-like objects or cometary material. Interplanetary dust collected nowadays on Earth is related to carbonaceous chondrites and to cometary material. They contain in particular at least a few percent of organic matter, organic compounds (amino-acids, PAHs,…, hydrous silicates, and could have largely contributed to the budget of prebiotic matter on Earth, about 4 Ga ago. A new population of cometary dust was recently discovered in the Concordia Antarctic micrometeorite collection. These “Ultracarbonaceous Antarctic Micrometeorites” (UCAMMs are dominated by deuterium-rich and nitrogen-rich organic matter. They seem related to the “CHON” grains identified in the comet Halley in 1986. Although rare in the micrometeorites flux (<5% of the micrometeorites, UCAMMs could have significantly contributed to the input of prebiotic matter. Their content in soluble organic matter is currently under study.

  2. Processing in (linear) systems with stochastic input

    Science.gov (United States)

    Nutu, Catalin Silviu; Axinte, Tiberiu

    2016-12-01

    The paper is providing a different approach to real-world systems, such as micro and macro systems of our real life, where the man has little or no influence on the system, either not knowing the rules of the respective system or not knowing the input of the system, being thus mainly only spectator of the system's output. In such a system, the input of the system and the laws ruling the system could be only "guessed", based on intuition or previous knowledge of the analyzer of the respective system. But, as we will see in the paper, it exists also another, more theoretical and hence scientific way to approach the matter of the real-world systems, and this approach is mostly based on the theory related to Schrödinger's equation and the wave function associated with it and quantum mechanics as well. The main results of the paper are regarding the utilization of the Schrödinger's equation and related theory but also of the Quantum mechanics, in modeling real-life and real-world systems.

  3. [Prosody, speech input and language acquisition].

    Science.gov (United States)

    Jungheim, M; Miller, S; Kühn, D; Ptok, M

    2014-04-01

    In order to acquire language, children require speech input. The prosody of the speech input plays an important role. In most cultures adults modify their code when communicating with children. Compared to normal speech this code differs especially with regard to prosody. For this review a selective literature search in PubMed and Scopus was performed. Prosodic characteristics are a key feature of spoken language. By analysing prosodic features, children gain knowledge about underlying grammatical structures. Child-directed speech (CDS) is modified in a way that meaningful sequences are highlighted acoustically so that important information can be extracted from the continuous speech flow more easily. CDS is said to enhance the representation of linguistic signs. Taking into consideration what has previously been described in the literature regarding the perception of suprasegmentals, CDS seems to be able to support language acquisition due to the correspondence of prosodic and syntactic units. However, no findings have been reported, stating that the linguistically reduced CDS could hinder first language acquisition.

  4. Input Subject Diversity Accelerates the Growth of Tense and Agreement: Indirect Benefits From a Parent-Implemented Intervention.

    Science.gov (United States)

    Hadley, Pamela A; Rispoli, Matthew; Holt, Janet K

    2017-09-18

    This follow-up study examined whether a parent intervention that increased the diversity of lexical noun phrase subjects in parent input and accelerated children's sentence diversity (Hadley et al., 2017) had indirect benefits on tense/agreement (T/A) morphemes in parent input and children's spontaneous speech. Differences in input variables related to T/A marking were compared for parents who received toy talk instruction and a quasi-control group: input informativeness and full is declaratives. Language growth on tense agreement productivity (TAP) was modeled for 38 children from language samples obtained at 21, 24, 27, and 30 months. Parent input properties following instruction and children's growth in lexical diversity and sentence diversity were examined as predictors of TAP growth. Instruction increased parent use of full is declaratives (ηp2 ≥ .25) but not input informativeness. Children's sentence diversity was also a significant time-varying predictor of TAP growth. Two input variables, lexical noun phrase subject diversity and full is declaratives, were also significant predictors, even after controlling for children's sentence diversity. These findings establish a link between children's sentence diversity and the development of T/A morphemes and provide evidence about characteristics of input that facilitate growth in this grammatical system.

  5. Conditional variable importance for random forests

    Directory of Open Access Journals (Sweden)

    Augustin Thomas

    2008-07-01

    Full Text Available Abstract Background Random forests are becoming increasingly popular in many scientific fields because they can cope with "small n large p" problems, complex interactions and even highly correlated predictor variables. Their variable importance measures have recently been suggested as screening tools for, e.g., gene expression studies. However, these variable importance measures show a bias towards correlated predictor variables. Results We identify two mechanisms responsible for this finding: (i A preference for the selection of correlated predictors in the tree building process and (ii an additional advantage for correlated predictor variables induced by the unconditional permutation scheme that is employed in the computation of the variable importance measure. Based on these considerations we develop a new, conditional permutation scheme for the computation of the variable importance measure. Conclusion The resulting conditional variable importance reflects the true impact of each predictor variable more reliably than the original marginal approach.

  6. Screening for colorectal cancer.

    Science.gov (United States)

    He, Jin; Efron, Jonathan E

    2011-01-01

    March is national colorectal cancer awareness month. It is estimated that as many as 60% of colorectal cancer deaths could be prevented if all men and women aged 50 years or older were screened routinely. In 2000, Katie Couric's televised colonoscopy led to a 20% increase in screening colonoscopies across America, a stunning rise called the "Katie Couric Effect". This event demonstrated how celebrity endorsement affects health behavior. Currently, discussion is ongoing about the optimal strategy for CRC screening, particularly the costs of screening colonoscopy. The current CRC screening guidelines are summarized in Table 2. Debates over the optimum CRC screening test continue in the face of evidence that 22 million Americans aged 50 to 75 years are not screened for CRC by any modality and 25,000 of those lives may have been saved if they had been screened for CRC. It is clear that improving screening rates and reducing disparities in underscreened communities and population subgroups could further reduce colorectal cancer morbidity and mortality. National Institutes of Health consensus identified the following priority areas to enhance the use and quality of colorectal cancer screening: Eliminate financial barriers to colorectal cancer screening and appropriate follow-up of positive results of colorectal cancer screening. Develop systems to ensure the high quality of colorectal cancer screening programs. Conduct studies to determine the comparative effectiveness of the various colorectal cancer screening methods in usual practice settings. Encouraging population adherence to screening tests and allowing patients to select the tests they prefer may do more good (as long as they choose something) than whatever procedure is chosen by the medical profession as the preferred test.

  7. [Colorectal cancer screening].

    Science.gov (United States)

    Castells, Antoni

    2015-09-01

    Colorectal cancer is one of malignancies showing the greatest benefit from preventive measures, especially screening or secondary prevention. Several screening strategies are available with demonstrated efficacy and efficiency. The most widely used are the faecal occult blood test in countries with population-based screening programmes, and colonoscopy in those conducting opportunistic screening. The present article reviews the most important presentations on colorectal cancer screening at the annual congress of the American Gastroenterological Association held in Washington in 2015, with special emphasis on the medium-term results of faecal occult blood testing strategies and determining factors and on strategies to reduce the development of interval cancer after colonoscopy.

  8. Multiple-Input Multiple-Output (MIMO Linear Systems Extreme Inputs/Outputs

    Directory of Open Access Journals (Sweden)

    David O. Smallwood

    2007-01-01

    Full Text Available A linear structure is excited at multiple points with a stationary normal random process. The response of the structure is measured at multiple outputs. If the autospectral densities of the inputs are specified, the phase relationships between the inputs are derived that will minimize or maximize the trace of the autospectral density matrix of the outputs. If the autospectral densities of the outputs are specified, the phase relationships between the outputs that will minimize or maximize the trace of the input autospectral density matrix are derived. It is shown that other phase relationships and ordinary coherence less than one will result in a trace intermediate between these extremes. Least favorable response and some classes of critical response are special cases of the development. It is shown that the derivation for stationary random waveforms can also be applied to nonstationary random, transients, and deterministic waveforms.

  9. The impact of temporal variability of biochemical markers PAPP-A and free β-hCG on the specificity of the first-trimester Down syndrome screening: a Croatian retrospective study

    Science.gov (United States)

    2010-01-01

    Background The variability of maternal serum biochemical markers for Down syndrome, free β-hCG and PAPP-A can have a different impact on false-positive rates between the 10+0 and 13+6 week of gestation. The study population comprised 2883 unaffected, singleton, spontaneously conceived pregnancies in Croatian women, who delivered apparently healthy child at term. Women were separated in 4 groups, dependently on the gestational week when the analyses of biochemical markers were performed. The concentrations of free β-hCG and PAPP-A in maternal serum were determined by solid-phase, enzyme-labeled chemiluminiscent immunometric assay (Siemens Immulite). Concentrations were converted to MoMs, according to centre-specific weighted regression median curves for both markers in unaffected pregnancies. The individual risks for trisomies 21, 18 and 13 were computed by Prisca 4.0 software. Findings There were no significant differences between the sub-groups, regarding maternal age, maternal weight and the proportion of smokers. The difference in log10 MoM free β-hCG values, between the 11th and 12th gestational week, was significant (p = 0.002). The difference in log10 MoM PAPP-A values between the 11th and 12th, and between 12th and 13th week of gestation was significant (p = 0.006 and p = 0.003, respectively). False-positive rates of biochemical risk for trisomies were 16.1% before the 11th week, 12.8% in week 12th, 11.9% in week 13th and 9.9% after week 13th. The differences were not statistically significant. Conclusions Biochemical markers (log10 MoMs) showed gestation related variations in the first-trimester unaffected pregnancies, although the variations could not be attributed either to the inaccuracy of analytical procedures or to the inappropriately settled curves of median values for the first-trimester biochemical markers. PMID:20630069

  10. Partial state and unknown input estimation for time-delay systems

    Science.gov (United States)

    Teh, P. S.; Trinh, H.

    2012-04-01

    This article considers the problem of estimating a partial set of the state vector and/or unknown input vector of linear systems driven by unknown inputs and time-varying delay in the state variables. Three types of reduced-order observers, namely, observers with delays, observers without internal delays and delay-free observers are proposed in this article. Existence conditions and design procedures are presented for the determination of parameters for each case of observers. Numerical examples are presented to illustrate the design procedures.

  11. Screen Practice in Curating

    DEFF Research Database (Denmark)

    Toft, Tanya Søndergaard

    2014-01-01

    During the past one and a half decade, a curatorial orientation towards "screen practice" has expanded the moving image and digital art into the public domain, exploring alternative artistic uses of the screen. The emergence of urban LED screens in the late 1990s provided a new venue that allowed...... for digital art to expand into public space. It also offered a political point of departure, inviting for confrontation with the Spectacle and with the politics and ideology of the screen as a mass communication medium that instrumentalized spectator positions. In this article I propose that screen practice...... to the dispositif of screen practice in curating, resulting in a medium-based curatorial discourse. With reference to the nomadic exhibition project Nordic Outbreak that I co-curated with Nina Colosi in 2013 and 2014, I suggest that the topos of the defined visual display area, frequently still known as "the screen...

  12. Developing the clinical components of a complex intervention for a glaucoma screening trial: a mixed methods study

    Directory of Open Access Journals (Sweden)

    2011-04-01

    Full Text Available Abstract Background Glaucoma is a leading cause of avoidable blindness worldwide. Open angle glaucoma is the most common type of glaucoma. No randomised controlled trials have been conducted evaluating the effectiveness of glaucoma screening for reducing sight loss. It is unclear what the most appropriate intervention to be evaluated in any glaucoma screening trial would be. The purpose of this study was to develop the clinical components of an intervention for evaluation in a glaucoma (open angle screening trial that would be feasible and acceptable in a UK eye-care service. Methods A mixed-methods study, based on the Medical Research Council (MRC framework for complex interventions, integrating qualitative (semi-structured interviews with 46 UK eye-care providers, policy makers and health service commissioners, and quantitative (economic modelling methods. Interview data were synthesised and used to revise the screening interventions compared within an existing economic model. Results The qualitative data indicated broad based support for a glaucoma screening trial to take place in primary care, using ophthalmic trained technical assistants supported by optometry input. The precise location should be tailored to local circumstances. There was variability in opinion around the choice of screening test and target population. Integrating the interview findings with cost-effectiveness criteria reduced 189 potential components to a two test intervention including either optic nerve photography or screening mode perimetry (a measure of visual field sensitivity with or without tonometry (a measure of intraocular pressure. It would be more cost-effective, and thus acceptable in a policy context, to target screening for open angle glaucoma to those at highest risk but for both practicality and equity arguments the optimal strategy was screening a general population cohort beginning at age forty. Conclusions Interventions for screening for open angle

  13. Analysis on relation between safety input and accidents

    Institute of Scientific and Technical Information of China (English)

    YAO Qing-guo; ZHANG Xue-mu; LI Chun-hui

    2007-01-01

    The number of safety input directly determines the level of safety, and there exists dialectical and unified relations between safety input and accidents. Based on the field investigation and reliable data, this paper deeply studied the dialectical relationship between safety input and accidents, and acquired the conclusions. The security situation of the coal enterprises was related to the security input rate, being effected little by the security input scale, and build the relationship model between safety input and accidents on this basis, that is the accident model.

  14. Auto Draw from Excel Input Files

    Science.gov (United States)

    Strauss, Karl F.; Goullioud, Renaud; Cox, Brian; Grimes, James M.

    2011-01-01

    The design process often involves the use of Excel files during project development. To facilitate communications of the information in the Excel files, drawings are often generated. During the design process, the Excel files are updated often to reflect new input. The problem is that the drawings often lag the updates, often leading to confusion of the current state of the design. The use of this program allows visualization of complex data in a format that is more easily understandable than pages of numbers. Because the graphical output can be updated automatically, the manual labor of diagram drawing can be eliminated. The more frequent update of system diagrams can reduce confusion and reduce errors and is likely to uncover symmetric problems earlier in the design cycle, thus reducing rework and redesign.

  15. Distribution Development for STORM Ingestion Input Parameters

    Energy Technology Data Exchange (ETDEWEB)

    Fulton, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-01

    The Sandia-developed Transport of Radioactive Materials (STORM) code suite is used as part of the Radioisotope Power System Launch Safety (RPSLS) program to perform statistical modeling of the consequences due to release of radioactive material given a launch accident. As part of this modeling, STORM samples input parameters from probability distributions with some parameters treated as constants. This report described the work done to convert four of these constant inputs (Consumption Rate, Average Crop Yield, Cropland to Landuse Database Ratio, and Crop Uptake Factor) to sampled values. Consumption rate changed from a constant value of 557.68 kg / yr to a normal distribution with a mean of 102.96 kg / yr and a standard deviation of 2.65 kg / yr. Meanwhile, Average Crop Yield changed from a constant value of 3.783 kg edible / m 2 to a normal distribution with a mean of 3.23 kg edible / m 2 and a standard deviation of 0.442 kg edible / m 2 . The Cropland to Landuse Database ratio changed from a constant value of 0.0996 (9.96%) to a normal distribution with a mean value of 0.0312 (3.12%) and a standard deviation of 0.00292 (0.29%). Finally the crop uptake factor changed from a constant value of 6.37e-4 (Bq crop /kg)/(Bq soil /kg) to a lognormal distribution with a geometric mean value of 3.38e-4 (Bq crop /kg)/(Bq soil /kg) and a standard deviation value of 3.33 (Bq crop /kg)/(Bq soil /kg)

  16. How sensitive are estimates of carbon fixation in agricultural models to input data?

    Directory of Open Access Journals (Sweden)

    Tum Markus

    2012-02-01

    Full Text Available Abstract Background Process based vegetation models are central to understand the hydrological and carbon cycle. To achieve useful results at regional to global scales, such models require various input data from a wide range of earth observations. Since the geographical extent of these datasets varies from local to global scale, data quality and validity is of major interest when they are chosen for use. It is important to assess the effect of different input datasets in terms of quality to model outputs. In this article, we reflect on both: the uncertainty in input data and the reliability of model results. For our case study analysis we selected the Marchfeld region in Austria. We used independent meteorological datasets from the Central Institute for Meteorology and Geodynamics and the European Centre for Medium-Range Weather Forecasts (ECMWF. Land cover / land use information was taken from the GLC2000 and the CORINE 2000 products. Results For our case study analysis we selected two different process based models: the Environmental Policy Integrated Climate (EPIC and the Biosphere Energy Transfer Hydrology (BETHY/DLR model. Both process models show a congruent pattern to changes in input data. The annual variability of NPP reaches 36% for BETHY/DLR and 39% for EPIC when changing major input datasets. However, EPIC is less sensitive to meteorological input data than BETHY/DLR. The ECMWF maximum temperatures show a systematic pattern. Temperatures above 20°C are overestimated, whereas temperatures below 20°C are underestimated, resulting in an overall underestimation of NPP in both models. Besides, BETHY/DLR is sensitive to the choice and accuracy of the land cover product. Discussion This study shows that the impact of input data uncertainty on modelling results need to be assessed: whenever the models are applied under new conditions, local data should be used for both input and result comparison.

  17. How sensitive are estimates of carbon fixation in agricultural models to input data?

    Science.gov (United States)

    Tum, Markus; Strauss, Franziska; McCallum, Ian; Günther, Kurt; Schmid, Erwin

    2012-02-01

    Process based vegetation models are central to understand the hydrological and carbon cycle. To achieve useful results at regional to global scales, such models require various input data from a wide range of earth observations. Since the geographical extent of these datasets varies from local to global scale, data quality and validity is of major interest when they are chosen for use. It is important to assess the effect of different input datasets in terms of quality to model outputs. In this article, we reflect on both: the uncertainty in input data and the reliability of model results. For our case study analysis we selected the Marchfeld region in Austria. We used independent meteorological datasets from the Central Institute for Meteorology and Geodynamics and the European Centre for Medium-Range Weather Forecasts (ECMWF). Land cover / land use information was taken from the GLC2000 and the CORINE 2000 products. For our case study analysis we selected two different process based models: the Environmental Policy Integrated Climate (EPIC) and the Biosphere Energy Transfer Hydrology (BETHY/DLR) model. Both process models show a congruent pattern to changes in input data. The annual variability of NPP reaches 36% for BETHY/DLR and 39% for EPIC when changing major input datasets. However, EPIC is less sensitive to meteorological input data than BETHY/DLR. The ECMWF maximum temperatures show a systematic pattern. Temperatures above 20°C are overestimated, whereas temperatures below 20°C are underestimated, resulting in an overall underestimation of NPP in both models. Besides, BETHY/DLR is sensitive to the choice and accuracy of the land cover product. This study shows that the impact of input data uncertainty on modelling results need to be assessed: whenever the models are applied under new conditions, local data should be used for both input and result comparison.

  18. Complex variables

    CERN Document Server

    Taylor, Joseph L

    2011-01-01

    The text covers a broad spectrum between basic and advanced complex variables on the one hand and between theoretical and applied or computational material on the other hand. With careful selection of the emphasis put on the various sections, examples, and exercises, the book can be used in a one- or two-semester course for undergraduate mathematics majors, a one-semester course for engineering or physics majors, or a one-semester course for first-year mathematics graduate students. It has been tested in all three settings at the University of Utah. The exposition is clear, concise, and lively

  19. Complex variables

    CERN Document Server

    Flanigan, Francis J

    2010-01-01

    A caution to mathematics professors: Complex Variables does not follow conventional outlines of course material. One reviewer noting its originality wrote: ""A standard text is often preferred [to a superior text like this] because the professor knows the order of topics and the problems, and doesn't really have to pay attention to the text. He can go to class without preparation."" Not so here-Dr. Flanigan treats this most important field of contemporary mathematics in a most unusual way. While all the material for an advanced undergraduate or first-year graduate course is covered, discussion

  20. Soil-Related Input Parameters for the Biosphere Model

    Energy Technology Data Exchange (ETDEWEB)

    A. J. Smith

    2004-09-09

    This report presents one of the analyses that support the Environmental Radiation Model for Yucca Mountain Nevada (ERMYN). The ''Biosphere Model Report'' (BSC 2004 [DIRS 169460]) describes the details of the conceptual model as well as the mathematical model and the required input parameters. The biosphere model is one of a series of process models supporting the postclosure Total System Performance Assessment (TSPA) for the Yucca Mountain repository. A schematic representation of the documentation flow for the Biosphere input to TSPA is presented in Figure 1-1. This figure shows the evolutionary relationships among the products (i.e., analysis and model reports) developed for biosphere modeling, and the biosphere abstraction products for TSPA, as identified in the ''Technical Work Plan for Biosphere Modeling and Expert Support'' (TWP) (BSC 2004 [DIRS 169573]). This figure is included to provide an understanding of how this analysis report contributes to biosphere modeling in support of the license application, and is not intended to imply that access to the listed documents is required to understand the contents of this report. This report, ''Soil-Related Input Parameters for the Biosphere Model'', is one of the five analysis reports that develop input parameters for use in the ERMYN model. This report is the source documentation for the six biosphere parameters identified in Table 1-1. The purpose of this analysis was to develop the biosphere model parameters associated with the accumulation and depletion of radionuclides in the soil. These parameters support the calculation of radionuclide concentrations in soil from on-going irrigation or ash deposition and, as a direct consequence, radionuclide concentration in other environmental media that are affected by radionuclide concentrations in soil. The analysis was performed in accordance with the TWP (BSC 2004 [DIRS 169573]) where the governing procedure

  1. Correlated neural variability in persistent state networks.

    Science.gov (United States)

    Polk, Amber; Litwin-Kumar, Ashok; Doiron, Brent

    2012-04-17

    Neural activity that persists long after stimulus presentation is a biological correlate of short-term memory. Variability in spiking activity causes persistent states to drift over time, ultimately degrading memory. Models of short-term memory often assume that the input fluctuations to neural populations are independent across cells, a feature that attenuates population-level variability and stabilizes persistent activity. However, this assumption is at odds with experimental recordings from pairs of cortical neurons showing that both the input currents and output spike trains are correlated. It remains unclear how correlated variability affects the stability of persistent activity and the performance of cognitive tasks that it supports. We consider the stochastic long-timescale attractor dynamics of pairs of mutually inhibitory populations of spiking neurons. In these networks, persistent activity was less variable when correlated variability was globally distributed across both populations compared with the case when correlations were locally distributed only within each population. Using a reduced firing rate model with a continuum of persistent states, we show that, when input fluctuations are correlated across both populations, they drive firing rate fluctuations orthogonal to the persistent state attractor, thereby causing minimal stochastic drift. Using these insights, we establish that distributing correlated fluctuations globally as opposed to locally improves network's performance on a two-interval, delayed response discrimination task. Our work shows that the correlation structure of input fluctuations to a network is an important factor when determining long-timescale, persistent population spiking activity.

  2. Robust input design for nonlinear dynamic modeling of AUV.

    Science.gov (United States)

    Nouri, Nowrouz Mohammad; Valadi, Mehrdad

    2017-09-01

    Input design has a dominant role in developing the dynamic model of autonomous underwater vehicles (AUVs) through system identification. Optimal input design is the process of generating informative inputs that can be used to generate the good quality dynamic model of AUVs. In a problem with optimal input design, the desired input signal depends on the unknown system which is intended to be identified. In this paper, the input design approach which is robust to uncertainties in model parameters is used. The Bayesian robust design strategy is applied to design input signals for dynamic modeling of AUVs. The employed approach can design multiple inputs and apply constraints on an AUV system's inputs and outputs. Particle swarm optimization (PSO) is employed to solve the constraint robust optimization problem. The presented algorithm is used for designing the input signals for an AUV, and the estimate obtained by robust input design is compared with that of the optimal input design. According to the results, proposed input design can satisfy both robustness of constraints and optimality. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  3. Against Comprehensible Input: The Input Hypothesis and the Development of Second-language Competence.

    Science.gov (United States)

    White, Lydia

    1987-01-01

    Discusses several objections to Krashen's Input Hypothesis which states that language acquisition is the learners' understanding of a language at a stage slightly higher than their current one because of their understanding of extralinguistic cues of the language. (Author/LMO)

  4. Effect of input compression and input frequency response on music perception in cochlear implant users.

    Science.gov (United States)

    Halliwell, Emily R; Jones, Linor L; Fraser, Matthew; Lockley, Morag; Hill-Feltham, Penelope; McKay, Colette M

    2015-06-01

    A study was conducted to determine whether modifications to input compression and input frequency response characteristics can improve music-listening satisfaction in cochlear implant users. Experiment 1 compared three pre-processed versions of music and speech stimuli in a laboratory setting: original, compressed, and flattened frequency response. Music excerpts comprised three music genres (classical, country, and jazz), and a running speech excerpt was compared. Experiment 2 implemented a flattened input frequency response in the speech processor program. In a take-home trial, participants compared unaltered and flattened frequency responses. Ten and twelve adult Nucleus Freedom cochlear implant users participated in Experiments 1 and 2, respectively. Experiment 1 revealed a significant preference for music stimuli with a flattened frequency response compared to both original and compressed stimuli, whereas there was a significant preference for the original (rising) frequency response for speech stimuli. Experiment 2 revealed no significant mean preference for the flattened frequency response, with 9 of 11 subjects preferring the rising frequency response. Input compression did not alter music enjoyment. Comparison of the two experiments indicated that individual frequency response preferences may depend on the genre or familiarity, and particularly whether the music contained lyrics.

  5. How Much Input Is Enough? Correlating Comprehension and Child Language Input in an Endangered Language

    Science.gov (United States)

    Meakins, Felicity; Wigglesworth, Gillian

    2013-01-01

    In situations of language endangerment, the ability to understand a language tends to persevere longer than the ability to speak it. As a result, the possibility of language revival remains high even when few speakers remain. Nonetheless, this potential requires that those with high levels of comprehension received sufficient input as children for…

  6. El análisis input-output

    Directory of Open Access Journals (Sweden)

    de Parada, Javier

    1964-07-01

    Full Text Available Economic development has been the permanent aim of the economic policy of every country. This requires a detailed knowledge of the relationships between the various economic activities, so that available resources can be applied to those activities that will lead to the greatest increase in the total national production, and also to the largest increment in labour vacancies, and exports. This optimum exploitation of available economic resources has been attempted width the introduction of the so called economic development plans. An important instrument in economic planning is the input output analysis. This article gives the basic hypotheses and the theoretical fundamentals underlying this type of analysis. From the latest input output table of Spanish economic activity, a secondary table has been prepared covering the aspects that affect construction most closely, so that the construction industry can also be subjected to this type of analysis. The predetermined variables have been taken to be the state provisions for future subsidies to the housing and road construction industries.Cuando en 1758 el Dr. F. Quesnay, médico de Luis XV, formula su famoso «Tableau Economique», las ideas sobre la interdependencia general de los sectores económicos calaron profundamente en el espíritu de los economistas de la época. La escuela fisiócrata, entonces en boga, consideraba el «dejar obrar» a las leyes naturales como la mejor forma de gobierno. Quesnay intuyó el movimiento natural circulatorio de los bienes económicos, y como fruto de sus investigaciones surgió el celebérrimo «Tableau Economique», que fue aclamado por sus contemporáneos como uno de los más grandes descubrimientos de la Historia.

  7. A Stochastic Collocation Method for Elliptic Partial Differential Equations with Random Input Data

    KAUST Repository

    Babuška, Ivo

    2010-01-01

    This work proposes and analyzes a stochastic collocation method for solving elliptic partial differential equations with random coefficients and forcing terms. These input data are assumed to depend on a finite number of random variables. The method consists of a Galerkin approximation in space and a collocation in the zeros of suitable tensor product orthogonal polynomials (Gauss points) in the probability space, and naturally leads to the solution of uncoupled deterministic problems as in the Monte Carlo approach. It treats easily a wide range of situations, such as input data that depend nonlinearly on the random variables, diffusivity coefficients with unbounded second moments, and random variables that are correlated or even unbounded. We provide a rigorous convergence analysis and demonstrate exponential convergence of the “probability error” with respect to the number of Gauss points in each direction of the probability space, under some regularity assumptions on the random input data. Numerical examples show the effectiveness of the method. Finally, we include a section with developments posterior to the original publication of this work. There we review sparse grid stochastic collocation methods, which are effective collocation strategies for problems that depend on a moderately large number of random variables.

  8. Screening in liver disease

    Institute of Scientific and Technical Information of China (English)

    Paolo Del Poggio; Marzio Mazzoleni

    2006-01-01

    A disease is suitable for screening if it is common, if the target population can be identified and reached and if both a good screening test and an effective therapy are available. Of the most common liver diseases only viral hepatitis and genetic hemochromatosis partially satisfy these conditions. Hepatitis C is common, the screening test is good and the therapy eliminates the virus in half of the cases, but problems arise in the definition of the target population. In fact generalized population screening is not endorsed by international guidelines,although some recommend screening immigrants from high prevalence countries. Opportunistic screening (case finding) of individuals with classic risk factors,such as transfusion before 1992 and drug addiction,is the most frequently used strategy, but there is disagreement whether prison inmates, individuals with a history of promiscuous or traumatic sex and health care workers should be screened. In a real practice setting the performance of opportunistic screening by general practitioners is low but can be ameliorated by training programs. Screening targeted to segments of the population or mass campaigns are expensive and therefore interventions should be aimed to improve opportunistic screening and the detection skills of general practitioners. Regarding genetic hemochromatosis there is insufficient evidence for population screening, but individual physicians can decide to screen racial groups with a high prevalence of the disease, such as people in early middle age and of northern European origin. In the other cases opportunistic screening of high risk individuals should be performed, with a high level of suspicion in case of unexplained liver disease, diabetes, juvenile artropathy, sexual dysfunction and skin pigmentation.

  9. A Study on the Input Hypothesis and Interaction Hypothesis

    Institute of Scientific and Technical Information of China (English)

    李雪清

    2016-01-01

    In Second Language Acquisition theory, input and interaction are considered as two key factors greatly influencing the learners’acquisition rate and quality, and therefore input and interaction research has been receiving increasing attention in re-cent years. Among the large amount of research, Krashen’s input hypothesis and Long’s interaction hypothesis are perhaps most influential theories, from which most of input and interaction studies have developed. Input hypothesis claims that compre-hensible input is the only one way to acquire language, whereas interaction hypothesis argues that interaction is necessary for language acquisition. Therefore,this thesis attempts to conduct a descriptive analysis between input hypothesis and interaction hypothesis, based on their basic ideas, theoretical basis, comparisons and empirical work. It concludes that input hypothesis and interaction hypothesis succeed in interpreting the process of language acquisition to some extent, and offer both theoretical and practical inspirations on second language teaching.

  10. Characterization of Input Current Interharmonics in Adjustable Speed Drives

    DEFF Research Database (Denmark)

    Soltani, Hamid; Davari, Pooya; Zare, Firuz

    2017-01-01

    -edge symmetrical regularly sampled Space Vector Modulation (SVM) technique, on the input current interharmonic components are presented and discussed. Particular attention is also given to the influence of the asymmetrical regularly sampled modulation technique on the drive input current interharmonics...

  11. STABILITY ANALYSIS OF THE DYNAMIC INPUT-OUTPUT SYSTEM

    Institute of Scientific and Technical Information of China (English)

    GuoChonghui; TangHuanwen

    2002-01-01

    The dynamic input-output model is well known in economic theory and practice. In this paper, the asymptotic stability and balanced growth solutions of the dynamic input-output system are considered. Under some natural assumptions which do not require the technical coefficient matrix to be indecomposable,it has been proved that the dynamic input-output system is not asymptotically stable and the closed dynamic input-output model has a balanced growth solution.

  12. Estimating nonstationary input signals from a single neuronal spike train

    OpenAIRE

    Kim, Hideaki; Shinomoto, Shigeru

    2012-01-01

    Neurons temporally integrate input signals, translating them into timed output spikes. Because neurons nonperiodically emit spikes, examining spike timing can reveal information about input signals, which are determined by activities in the populations of excitatory and inhibitory presynaptic neurons. Although a number of mathematical methods have been developed to estimate such input parameters as the mean and fluctuation of the input current, these techniques are based on the unrealistic as...

  13. Input modelling for subchannel analysis of CANFLEX fuel bundle

    Energy Technology Data Exchange (ETDEWEB)

    Park, Joo Hwan; Jun, Ji Su; Suk, Ho Chun [Korea Atomic Energy Research Institute, Taejon (Korea)

    1998-06-01

    This report describs the input modelling for subchannel analysis of CANFLEX fuel bundle using CASS(Candu thermalhydraulic Analysis by Subchannel approacheS) code which has been developed for subchannel analysis of CANDU fuel channel. CASS code can give the different calculation results according to users' input modelling. Hence, the objective of this report provide the background information of input modelling, the accuracy of input data and gives the confidence of calculation results. (author). 11 refs., 3 figs., 4 tabs.

  14. Regional Input Output Table for the State of Punjab

    OpenAIRE

    Singh, Inderjeet; Singh, Lakhwinder

    2011-01-01

    Because of policy relevance of regional input-output analysis, a vast literature on the construction of regional input-output tables has emerged in the recent past, especially on the non-survey and hybrid methods. Although, construction of regional input-output tables is not new in India, but generation of input-output table using non-survey methods is relatively a rare phenomenon. This work validates alternative non-survey, location quotient methodologies and finally uses comparatively bette...

  15. Do Variations in Detrital Inputs Influence Stable Soil Organic Matter? - An Experimental Approach

    Science.gov (United States)

    Lajtha, K.; Townsend, K.; Brewer, E.; Caldwell, B.; Kalbitz, K.; Plante, A.

    2007-12-01

    Recognition of the importance of feedbacks from plants in determining soil nutrient dynamics and C storage led to a large number of litter decomposition studies. Despite growing knowledge of short-term litter dynamics, we know relatively little about the fate of plant litter and its role in determining SOM content and nutrient cycling over time scales ranging from decades and centuries. To address this gap, we established long-term studies of controls on soil organic matter formation in an old-growth forest at the H.J. Andrews Experimental Forest, OR. This study complements a network of recently established similar experiments that pan climatic and soil gradients, as well as the original DIRT experiment established in the Wisconsin Arboretum in 1956 in both grassland and forested sites. The central goal of the DIRT project is to assess how rates and sources of plant litter inputs control the accumulation and dynamics of organic matter and nutrients in forest soils over decadal time scales. Treatment plots include doubled litter (needle) inputs , doubled wood, no above ground litter (screened) inputs, no root inputs (trenched), and no inputs (screened and trenched). For the 50th anniversary of the Wisconsin sites and the 10th anniversary of the H.J. Andrews site, we used sequential density fractionation of soils from all treatments to determine if adding or removing either below- or above-ground litter inputs influenced carbon stabilization as soil organic matter. After 50 years, double litter plots in both prairie and forested soils had higher %C in the 0-10 cm horizon. In the forested site, plots showed increased C content of the lightest fraction, which represents relatively young SOM with a short turnover time. However, the first two heavy fractions also showed increases in C with added aboveground litter, suggesting the importance of aboveground litter inputs to SOM in the forest. No such pattern existed for the prairie soil, and we hypothesize that this is

  16. Impact of magnetic saturation on the input-output linearising tracking control of an induction motor

    DEFF Research Database (Denmark)

    Dolinar, Drago; Ljusev, Petar; Stumberger, Gorazd

    2004-01-01

    This paper deals with the tracking control design of an induction motor, based on input-output linearization with magnetic saturation included. Magnetic saturation is represented by the nonlinear magnetizing curve of the iron core and is used in the control design, the observer of state variables......, and in the load torque estimator. An input-output linearising control is used to achieve better tracking performances of the drive. It is based on the mixed ”stator current - rotor flux linkage” induction motor model with magnetic saturation considered in the stationary reference frame. Experimental results show...... that the proposed input-output linearising tracking control with the included saturation behaves considerably better than the one without saturation, and that it introduces smaller position and speed errors, and better motor stiffness on account of the increased computational complexity....

  17. Input-output linearizing tracking control of induction machine with the included magnetic saturation

    DEFF Research Database (Denmark)

    Dolinar, Drago; Ljusev, Petar; Stumberger, Gorazd

    2003-01-01

    The tracking control design of an induction motor, based on input-output linearisation with magnetic saturation included is addressed. The magnetic saturation is represented by a nonlinear magnetising curve for the iron core and is used in the control, the observer of the state variables......, and in the load torque estimator. An input-output linearising control is used to achieve better tracking performances. It is based on the mixed 'stator current - rotor flux linkage' induction motor model with magnetic saturation considered in the stationary reference frame. Experimental results show...... that the proposed input-output linearising tracking control with saturation included behaves considerably better than the one without saturation, and that it introduces smaller position and speed errors, and better motor stiffness on account of the increased computational complexity....

  18. Impact of magnetic saturation on the input-output linearising tracking control of an induction motor

    DEFF Research Database (Denmark)

    Dolinar, Drago; Ljusev, Petar; Stumberger, Gorazd

    2004-01-01

    This paper deals with the tracking control design of an induction motor, based on input-output linearization with magnetic saturation included. Magnetic saturation is represented by the nonlinear magnetizing curve of the iron core and is used in the control design, the observer of state variables......, and in the load torque estimator. An input-output linearising control is used to achieve better tracking performances of the drive. It is based on the mixed ”stator current - rotor flux linkage” induction motor model with magnetic saturation considered in the stationary reference frame. Experimental results show...... that the proposed input-output linearising tracking control with the included saturation behaves considerably better than the one without saturation, and that it introduces smaller position and speed errors, and better motor stiffness on account of the increased computational complexity....

  19. Input-output linearizing tracking control of induction machine with the included magnetic saturation

    DEFF Research Database (Denmark)

    Dolinar, Drago; Ljusev, Petar; Stumberger, Gorazd

    2003-01-01

    The tracking control design of an induction motor, based on input-output linearisation with magnetic saturation included is addressed. The magnetic saturation is represented by a nonlinear magnetising curve for the iron core and is used in the control, the observer of the state variables......, and in the load torque estimator. An input-output linearising control is used to achieve better tracking performances. It is based on the mixed 'stator current - rotor flux linkage' induction motor model with magnetic saturation considered in the stationary reference frame. Experimental results show...... that the proposed input-output linearising tracking control with saturation included behaves considerably better than the one without saturation, and that it introduces smaller position and speed errors, and better motor stiffness on account of the increased computational complexity....

  20. Seasonal variability in the input of lead, barium and indium to Law Dome, Antarctica

    DEFF Research Database (Denmark)

    Burn-Nunes...[], L.J.; Vallelonga, Paul Travis; Loss, R.D.

    2011-01-01

    Lead (Pb) isotopic compositions and concentrations, and barium (Ba) and indium (In) concentrations have been determined at monthly resolution in five Law Dome (coastal Eastern Antarctica) ice core sections dated from similar to 1757 AD to similar to 1898 AD. 'Natural' background Pb concentrations...... more impurity laden air from the Southern Hemisphere continental regions to Eastern Antarctica and Law Dome. As this Pb is isotopically identical to that emitted from south-eastern Australia (Broken Hill, Port Pine) this implies a relatively direct air trajectory pathway from southern Australia to Law...

  1. A Non-Simulation Based Method for Inducing Pearson’s Correlation Between Input Random Variables

    Science.gov (United States)

    2008-04-23

    Thanks to Dr. Steven Book of MCR for his help in obtaining copies of several papers on correlation modules, without which this paper would not have been...risks, not estimating variation SWBS Description Upside Probable Downside 000 Administration 100 Hull 200 Propulsion 300 Electric Plant 400 Electonics ...Systems 500 Auxillary Systems 600 Outfit & Furnishings 700 Weapons 800 Integration & Engineering 900 Ship Assembly & Support Total SWBS Description

  2. Catchment2Coast: making the link between coastal resource variability and river inputs

    CSIR Research Space (South Africa)

    Monteiro, P

    2003-07-01

    Full Text Available boundaries, including the tradi- tional ones between river catchments and their adjacent coastal ecosystems. The Catchment2Coast Project aims to address these gaps in knowledge using a combination of numerical modelling and field observations... refinement of numerical modelling plat- forms, affording them the necessary degree of rigour and reliability for more generic usage as management and policy development support tools. The project uses as a case study the Incomati River–Maputo Bay system...

  3. A Variable Input-Output Model for Inflation, Growth, and Energy for the Korean Economy.

    Science.gov (United States)

    1983-12-01

    and the sales price of cukput as determinan-s of the technical coefficients were suggested by Walras [Ref. 4] and many other eco.cmis.s. (Ref. 5] Arrow...1967, 1975 and 1979. Seoul,Ko:rea: Fesearch Department. S. 4. Walras , L. Elemerts of Pure Economics, (3nglish Edition). George Allen and Urwin

  4. Screening for Atrial Fibrillation

    DEFF Research Database (Denmark)

    Freedman, Ben; Camm, A. John; Calkins, Hugh

    2017-01-01

    in September 2015 to promote discussion and research about AF screening as a strategy to reduce stroke and death and to provide advocacy for implementation of country-specific AF screening programs. During 2016, 60 expert members of AF-SCREEN, including physicians, nurses, allied health professionals, health...... economists, and patient advocates, were invited to prepare sections of a draft document. In August 2016, 51 members met in Rome to discuss the draft document and consider the key points arising from it using a Delphi process. These key points emphasize that screen-detected AF found at a single timepoint...... that guidelines require for AF diagnosis and would therefore be preferred as screening tools. Certain patient groups, such as those with recent embolic stroke of uncertain source (ESUS), require more intensive monitoring for AF. Settings for screening include various venues in both the community and the clinic...

  5. 42 CFR 460.138 - Committees with community input.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Committees with community input. 460.138 Section 460.138 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... community input. A PACE organization must establish one or more committees, with community input, to do...

  6. Comparison of Linear Microinstability Calculations of Varying Input Realism

    Energy Technology Data Exchange (ETDEWEB)

    G. Rewoldt

    2003-09-08

    The effect of varying ''input realism'' or varying completeness of the input data for linear microinstability calculations, in particular on the critical value of the ion temperature gradient for the ion temperature gradient mode, is investigated using gyrokinetic and gyrofluid approaches. The calculations show that varying input realism can have a substantial quantitative effect on the results.

  7. On the Nature of the Input in Optimality Theory

    DEFF Research Database (Denmark)

    Heck, Fabian; Müller, Gereon; Vogel, Ralf;

    2002-01-01

    The input has two main functions in optimality theory (Prince and Smolensky 1993). First, the input defines the candidate set, in other words it determines which output candidates compete for optimality, and which do not. Second, the input is referred to by faithfulness constraints that prohibit...

  8. REFLECTIONS ON THE INOPERABILITY INPUT-OUTPUT MODEL

    NARCIS (Netherlands)

    Dietzenbacher, Erik; Miller, Ronald E.

    2015-01-01

    We argue that the inoperability input-output model is a straightforward - albeit potentially very relevant - application of the standard input-output model. In addition, we propose two less standard input-output approaches as alternatives to take into consideration when analyzing the effects of disa

  9. Waste treatment in physical input-output analysis

    NARCIS (Netherlands)

    Dietzenbacher, E

    2005-01-01

    When compared to monetary input-output tables (MIOTs), a distinctive feature of physical input-output tables (PIOTs) is that they include the generation of waste as part of a consistent accounting framework. As a consequence, however, physical input-output analysis thus requires that the treatment o

  10. Screening for colorectal cancer

    DEFF Research Database (Denmark)

    Nielsen, Hans J; Jakobsen, Karen V; Christensen, Ib J

    2011-01-01

    Emerging results indicate that screening improves survival of patients with colorectal cancer. Therefore, screening programs are already implemented or are being considered for implementation in Asia, Europe and North America. At present, a great variety of screening methods are available including...... into improvements of screening for colorectal cancer includes blood-based biological markers, such as proteins, DNA and RNA in combination with various demographically and clinically parameters into a "risk assessment evaluation" (RAE) test. It is assumed that such a test may lead to higher acceptance among...... procedures for colorectal cancer. Therefore, results of present research, validating RAE tests, are awaited with interest....

  11. Lung cancer screening

    Energy Technology Data Exchange (ETDEWEB)

    Kazerooni, E.A. [Univ. of Michigan Medical Center, Ann Arbor, MI (United States)

    2005-11-15

    Lung cancer screening with CT remains controversial. Lung cancer is the leading cause of cancer death. To date, no screening test has been demonstrated to reduce mortality. Given the large population of adult cigarette smokers and former smokers worldwide, there is a large population at risk for lung cancer. While a lot has been learned from prospective single-arm cohort studies about the feasibility of performing annual CT to screen for lung cancer, many questions have also been raised. While we know that screening for lung cancer with CT detects many small nodules, with up to half the subjects having a positive baseline screen, and up to 75% of subjects having a positive screen at least once if screened annually for 5 years, the great majority of these nodules exhibit benign biologic behavior. The innumerable small nodules detected with screening CT, and diagnostic chest CT in general, present a daily clinical challenge, and result in extensive medical resource utilization and additional radiation exposure. Algorithms for how and when to follow small nodules detected on CT are in evolution. Ongoing studies are designed to determine if lung cancer screening with CT reduces lung cancer mortality. (orig.)

  12. [Overdiagnosis in cancer screening].

    Science.gov (United States)

    Cervera Deval, J; Sentís Crivillé, M; Zulueta, J J

    2015-01-01

    In screening programs, overdiagnosis is defined as the detection of a disease that would have gone undetected without screening when that disease would not have resulted in morbimortality and was treated unnecessarily. Overdiagnosis is a bias inherent in screening and an undesired effect of secondary prevention and improved sensitivity of diagnostic techniques. It is difficult to discriminate a priori between clinically relevant diagnoses and those in which treatment is unnecessary. To minimize the effects of overdiagnosis, screening should be done in patients at risk. Copyright © 2014 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

  13. Colorectal cancer screening.

    Science.gov (United States)

    Chan, Pak Wo Webber; Ngu, Jing Hieng; Poh, Zhongxian; Soetikno, Roy

    2017-01-01

    Colorectal cancer, which is the leading cancer in Singapore, can be prevented by increased use of screening and polypectomy. A range of screening strategies such as stool-based tests, flexible sigmoidoscopy, colonoscopy and computed tomography colonography are available, each with different strengths and limitations. Primary care physicians should discuss appropriate screening modalities with their patients, tailored to their individual needs. Physicians, patients and the government should work in partnership to improve uptake of colorectal cancer screening to reduce the morbidity and mortality from colorectal cancer. Copyright: © Singapore Medical Association.

  14. Colorectal cancer screening

    Directory of Open Access Journals (Sweden)

    Almeida Frederico Ferreira Novaes de

    2000-01-01

    Full Text Available Colorectal cancer (CRC is the third most common cancer in the world, and mortality has remained the same for the past 50 years, despite advances in diagnosis and treatment. Because significant numbers of patients present with advanced or incurable stages, patients with pre-malignant lesions (adenomatous polyps that occur as result of genetic inheritance or age should be screened, and patients with long-standing inflammatory bowel disease should undergo surveillance. There are different risk groups for CRC, as well as different screening strategies. It remains to be determined which screening protocol is the most cost-effective for each risk catagory. The objective of screening is to reduce morbidity and mortality in a target population. The purpose of this review is to analyze the results of the published CRC screening studies, with regard to the measured reduction of morbidity and mortality, due to CRC in the studied populations, following various screening procedures. The main screening techniques, used in combination or alone, include fecal occult blood tests, flexible sigmoidoscopy, and colonoscopy. Evidence from the published literature on screening methods for specific risk groups is scanty and frequently does not arise from controlled studies. Nevertheless, data from these studies, combined with recent advances in molecular genetics, certainly lead the way to greater efficacy and lower cost of CRC screening.

  15. ScreenOS Cookbook

    CERN Document Server

    Brunner, Stefan; Delcourt, David

    2008-01-01

    In the only book that completely covers ScreenOS, six key members of Juniper Network's ScreenOS development team help you troubleshoot secure networks using ScreenOS firewall appliances. Over 200 recipes address a wide range of security issues, provide step-by-step solutions, and include discussions of why the recipes work, so you can easily set up and keep ScreenOS systems on track. The easy-to-follow format enables you to find the topic and specific recipe you need right away.

  16. Fine motor control of the jaw following alteration of orofacial afferent inputs.

    Science.gov (United States)

    Kumar, Abhishek; Castrillon, Eduardo; Trulsson, Mats; Svensson, Krister G; Svensson, Peter

    2017-03-01

    The study was designed to investigate if alteration of different orofacial afferent inputs would have different effects on oral fine motor control and to test the hypothesis that reduced afferent inputs will increase the variability of bite force values and jaw muscle activity, and repeated training with splitting of food morsel in conditions with reduced afferent inputs would decrease the variability and lead to optimization of bite force values and jaw muscle activity. Forty-five healthy volunteers participated in a single experimental session and were equally divided into incisal, mucosal, and block anesthesia groups. The participants performed six series (with ten trials) of a standardized hold and split task after the intervention with local anesthesia was made in the respective groups. The hold and split forces along with the corresponding jaw muscle activity were recorded and compared to a reference group. The hold force and the electromyographic (EMG) activity of the masseter muscles during the hold phase were significantly higher in the incisal and block anesthesia group, as compared to the reference group (P motor control. Further, inhibition of afferent inputs from the orofacial or periodontal mechanoreceptors did not increase the variability of bite force values and jaw muscle activity; indicating that the relative precision of the oral fine motor task was not compromised inspite of the anesthesia. The results also suggest the propensity of optimization of bite force values and jaw muscle activity due to repeated splitting of the food morsels, inspite of alteration of sensory inputs. Skill acquisition following a change in oral sensory environment is crucial for understanding how humans learn and re-learn oral motor behaviors and the kind of adaptation that takes place after successful oral rehabilitation procedures.

  17. Comparison between Input Hypothesis and Interaction Hypothesis

    Institute of Scientific and Technical Information of China (English)

    宗琦

    2016-01-01

    Second Language Acquisition has received more and more attention since 1950s when it becomes an autonomous field of research. Linguists have carried out many theoretical and empirical studies with a sharp purpose to promote Second Language Acquisition. Krashen’s Input Hypothesis and Long’s Interaction Hypothesis are most influential ones among the studies. They both play important roles in language teaching and learning. The paper will present an account of the two great theories, includ-ing the main claims, theoretical foundations as well as some related empirical works and try to investigate commons and differ-ences between them, based on literature and empirical studies. The purpose of writing this paper is to provide a clear outline of the two theories and point out how they are interrelated yet separate predictions about how second language are learned. It is meaningful because the results can be valuable guidance and highlights for language teachers and learners to teach or acquire a language better.

  18. Investigating Text Input Methods for Mobile Phones

    Directory of Open Access Journals (Sweden)

    Barry O’Riordan

    2005-01-01

    Full Text Available Human Computer Interaction is a primary factor in the success or failure of any device but if an objective view is taken of the current mobile phone market you would be forgiven for thinking usability was secondary to aesthetics. Many phone manufacturers modify the design of phones to be different than the competition and to target fashion trends, usually at the expense of usability and performance. There is a lack of awareness among many buyers of the usability of the device they are purchasing and the disposability of modern technology is an effect rather than a cause of this. Designing new text entry methods for mobile devices can be expensive and labour-intensive. The assessment and comparison of a new text entry method with current methods is a necessary part of the design process. The best way to do this is through an empirical evaluation. The aim of the study was to establish which mobile phone text input method best suits the requirements of a select group of target users. This study used a diverse range of users to compare devices that are in everyday use by most of the adult population. The proliferation of the devices is as yet unmatched by the study of their application and the consideration of their user friendliness.

  19. Multi-Touch Screen Interfaces And Gesture Analysis: A Study

    Directory of Open Access Journals (Sweden)

    Mrudula Nimbarte

    2011-12-01

    Full Text Available The way how we handle computers today will soon change. The future technology will allow us tointeract with the computer on different level from the current technology what we are used to. The toolssuch as the mouse and the keyboard need to communicate with the computer will slowly disappearand be replaced with more comfortable and more natural tools for the human being to use. That future isalready here. The rate of how touch screen hardware and applications are used is growing rapidlyand will break new r e c o r ds in n e a r f ut u r e . This new technology requires different ways ofdetecting inputs from the user - inputs which will be made out of on- screen gestures rather than byclicking of buttons or scrolling mouse wheels. In this paper we s tudied the gestures defined formulti-touch screen interfaces, the methods used to detect them and how they are passed on to otherapplications.

  20. Parvalbumin-producing cortical interneurons receive inhibitory inputs on proximal portions and cortical excitatory inputs on distal dendrites.

    Science.gov (United States)

    Kameda, Hiroshi; Hioki, Hiroyuki; Tanaka, Yasuyo H; Tanaka, Takuma; Sohn, Jaerin; Sonomura, Takahiro; Furuta, Takahiro; Fujiyama, Fumino; Kaneko, Takeshi

    2012-03-01

    To examine inputs to parvalbumin (PV)-producing interneurons, we generated transgenic mice expressing somatodendritic membrane-targeted green fluorescent protein specifically in the interneurons, and completely visualized their dendrites and somata. Using immunolabeling for vesicular glutamate transporter (VGluT)1, VGluT2, and vesicular GABA transporter, we found that VGluT1-positive terminals made contacts 4- and 3.1-fold more frequently with PV-producing interneurons than VGluT2-positive and GABAergic terminals, respectively, in the primary somatosensory cortex. Even in layer 4, where VGluT2-positive terminals were most densely distributed, VGluT1-positive inputs to PV-producing interneurons were 2.4-fold more frequent than VGluT2-positive inputs. Furthermore, although GABAergic inputs to PV-producing interneurons were as numerous as VGluT2-positive inputs in most cortical layers, GABAergic inputs clearly preferred the proximal dendrites and somata of the interneurons, indicating that the sites of GABAergic inputs were more optimized than those of VGluT2-positive inputs. Simulation analysis with a PV-producing interneuron model compatible with the present morphological data revealed a plausible reason for this observation, by showing that GABAergic and glutamatergic postsynaptic potentials evoked by inputs to distal dendrites were attenuated to 60 and 87%, respectively, of those evoked by somatic inputs. As VGluT1-positive and VGluT2-positive axon terminals were presumed to be cortical and thalamic glutamatergic inputs, respectively, cortical excitatory inputs to PV-producing interneurons outnumbered the thalamic excitatory and intrinsic inhibitory inputs more than two-fold in any cortical layer. Although thalamic inputs are known to evoke about two-fold larger unitary excitatory postsynaptic potentials than cortical ones, the present results suggest that cortical inputs control PV-producing interneurons at least as strongly as thalamic inputs.

  1. Screen failure data in clinical trials: Are screening logs worth it?

    Science.gov (United States)

    Elm, Jordan J; Palesch, Yuko; Easton, J Donald; Lindblad, Anne; Barsan, William; Silbergleit, Robert; Conwit, Robin; Dillon, Catherine; Farrant, Mary; Battenhouse, Holly; Perlmutter, Aaron; Johnston, S Claiborne

    2014-08-01

    Clinical trials frequently spend considerable effort to collect data on patients who were assessed for eligibility but not enrolled. The Consolidated Standards of Reporting Trials (CONSORT) guidelines' recommended flow diagram for randomized clinical trials reinforces the belief that the collection of screening data is a necessary and worthwhile endeavor. The rationale for collecting screening data includes scientific, trial management, and ethno-socio-cultural reasons. We posit that the cost of collecting screening data is not justified, in part due to inability to centrally monitor and verify the screening data in the same manner as other clinical trial data. To illustrate the effort and site-to-site variability, we analyzed the screening data from a multicenter, randomized clinical trial of patients with transient ischemic attack or minor ischemic stroke (Platelet-Oriented Inhibition in New Transient Ischemic Attack and Minor Ischemic Stroke (POINT)). Data were collected on over 27,000 patients screened across 172 enrolling sites, 95% of whom were not enrolled. Although the rate of return of screen failure logs was high overall (95%), there were a considerable number of logs that were returned with 'no data to report' (23%), often due to administrative reasons rather than no patients screened. In spite of attempts to standardize the collection of screening data, due to differences in site processes, multicenter clinical trials face challenges in collecting those data completely and uniformly. The efforts required to centrally collect high-quality data on an extensive number of screened patients may outweigh the scientific value of the data. Moreover, the lack of a standardized definition of 'screened' and the challenges of collecting meaningful characteristics for patients who have not signed consent limits the ability to compare across studies and to assess generalizability and selection bias as intended. © The Author(s), 2014.

  2. Interleaved Boost-Half-Bridge Dual–Input DC-DC Converter with a PWM plus Phase-Shift Control for Fuel Cell Applications

    DEFF Research Database (Denmark)

    Zhang, Zhe; Andersen, Michael A. E.

    2013-01-01

    This paper presents an isolated dual-input DC-DC converter with a PWM plus phase-shift control for fuel cell hybrid energy systems. The power switches are controlled by phase shifted PWM signals with a variable duty cycle, and thus the two input voltages as well as the output voltage can...

  3. Inductor Compensation in Three Phase PFC Control with Decoupling the Input Voltage and Bus Voltage

    Directory of Open Access Journals (Sweden)

    Luo Guang

    2016-01-01

    Full Text Available As the nonlinear structure of the boost ac/dc topology, the PFC is difficult to be controlled. The average state space theory has revealed that the choke current is determined by duty-ratio coupled with input voltage and bus voltage, which makes the high-performance sine-wave current track control more challenging. To remove disturbing variables and reduce the zero-crossing distortion, the decoupling control strategy is presented. Also, it is shown in this paper that the variable inductance has a great influence on PFC and THDI. As the inductor in boost converter varies with the current, a compensating coefficient of current is also proposed. The decoupling strategy and the inductor compensation strategy are implemented on a UPS with three phase input voltage. Numerical simulation and experimental results has indicated the high-performance of these control strategy.

  4. A linearized input-output representation of flexible multibody systems for control synthesis

    Energy Technology Data Exchange (ETDEWEB)

    Jonker, J. B., E-mail: J.B.Jonker@utwente.nl; Aarts, R. G. K. M., E-mail: R.G.K.M.Aarts@utwente.nl; Dijk, J. van [University of Twente, Faculty of Engineering Technology (Netherlands)], E-mail: J.vanDijk@utwente.nl

    2009-03-15

    In this paper, a linearized input-output representation of flexible multibody systems is proposed in which an arbitrary combination of positions, velocities, accelerations, and forces can be taken as input variables and as output variables. The formulation is based on a nonlinear finite element approach in which a multibody system is modeled as an assembly of rigid body elements interconnected by joint elements such as flexible hinges and beams. The proposed formulation is general in nature and can be applied for prototype modeling and control system analysis of mechatronic systems. Application of the theory is illustrated through a detailed model development of an active vibration isolation system for a metrology frame of a lithography machine.

  5. Evaluation of Piloted Inputs for Onboard Frequency Response Estimation

    Science.gov (United States)

    Grauer, Jared A.; Martos, Borja

    2013-01-01

    Frequency response estimation results are presented using piloted inputs and a real-time estimation method recently developed for multisine inputs. A nonlinear simulation of the F-16 and a Piper Saratoga research aircraft were subjected to different piloted test inputs while the short period stabilator/elevator to pitch rate frequency response was estimated. Results show that the method can produce accurate results using wide-band piloted inputs instead of multisines. A new metric is introduced for evaluating which data points to include in the analysis and recommendations are provided for applying this method with piloted inputs.

  6. 盲用多点触摸输入法的设计与实现%DESIGN AND IMPLEMENTATION OF MULTI-TOUCH INPUT METHOD FOR BLIND USAGE

    Institute of Scientific and Technical Information of China (English)

    张居晓; 曾晓勤; 孟朝晖

    2015-01-01

    With the popularity of smart phones and other electronic products,the application of multi-touch screen has been increasingly widespread.However,since the smooth surface of the touch screen,the blinds cannot get the information through touching the screen,and it results in the difficulty for the blinds to input words on touch screen as well.The paper presents the Chinese input method by using online handwritten braille recognition technology with multi-touch gestures.This work not only enables the blinds to input text information through multi-point touch screen,but can also be applied to the sighted person in Chinese input with touch screen online handwritten braille recognition,and the speed of Chinese writing is much higher than existing handwriting input method for touch screen.%随着智能手机等电子产品的普及,多点触摸屏应用越来越广泛。但是因触摸屏表面较光滑,使得盲人不能通过触觉获得屏幕的信息,造成其输入文字困难。提出采用多点触摸联机手写识别盲文技术的汉字输入法。该方法不仅解决了盲人能利用多点触摸屏输入文字信息,也能应用于明眼人的触摸屏联机手写盲文识别进行汉字输入,其书写汉字速度远高于现有的触摸屏的手写输入法。

  7. Sedimentary iron inputs stimulate seagrass ( Posidonia oceanica) population growth in carbonate sediments

    Science.gov (United States)

    Marbà, Núria; Duarte, Carlos M.; Holmer, Marianne; Calleja, Maria Ll.; Álvarez, Elvira; Díaz-Almela, Elena; Garcias-Bonet, Neus

    2008-02-01

    The relationship between sedimentary Fe inputs and net seagrass population growth across a range of Posidonia oceanica meadows growing in carbonate Mediterranean sediments (Balearic Islands, Spain; SE Iberian Peninsula, Spain; Limassol, Cyprus; Sounion, Greece) was examined using comparative analysis. Sedimentary Fe inputs were measured using benthic sediment traps and the net population growth of P. oceanica meadows was assessed using direct census of tagged plants. The meadows examined ranged from meadows undergoing a severe decline to expanding meadows (specific net population growth, from -0.14 yr -1 to 0.05 yr -1). Similarly, Fe inputs to the meadows ranged almost an order of magnitude across meadows (8.6-69.1 mg Fe m -2 d -1). There was a significant, positive relationship between sedimentary iron inputs and seagrass net population growth, accounting for 36% of the variability in population growth across meadows. The relationship obtained suggested that seagrass meadows receiving Fe inputs below 43 mg Fe m -2 d -1 are vulnerable and in risk of decline, confirming the pivotal role of Fe in the control of growth and the stability of seagrass meadows in carbonate sediments.

  8. A new algorithm for importance analysis of the inputs with distribution parameter uncertainty

    Science.gov (United States)

    Li, Luyi; Lu, Zhenzhou

    2016-10-01

    Importance analysis is aimed at finding the contributions by the inputs to the uncertainty in a model output. For structural systems involving inputs with distribution parameter uncertainty, the contributions by the inputs to the output uncertainty are governed by both the variability and parameter uncertainty in their probability distributions. A natural and consistent way to arrive at importance analysis results in such cases would be a three-loop nested Monte Carlo (MC) sampling strategy, in which the parameters are sampled in the outer loop and the inputs are sampled in the inner nested double-loop. However, the computational effort of this procedure is often prohibitive for engineering problem. This paper, therefore, proposes a newly efficient algorithm for importance analysis of the inputs in the presence of parameter uncertainty. By introducing a 'surrogate sampling probability density function (SS-PDF)' and incorporating the single-loop MC theory into the computation, the proposed algorithm can reduce the original three-loop nested MC computation into a single-loop one in terms of model evaluation, which requires substantially less computational effort. Methods for choosing proper SS-PDF are also discussed in the paper. The efficiency and robustness of the proposed algorithm have been demonstrated by results of several examples.

  9. Soft Sensor for Inputs and Parameters Using Nonlinear Singular State Observer in Chemical Processes

    Institute of Scientific and Technical Information of China (English)

    许锋; 汪晔晔; 罗雄麟

    2013-01-01

    Chemical processes are usually nonlinear singular systems. In this study, a soft sensor using nonlinear singular state observer is established for unknown inputs and uncertain model parameters in chemical processes, which are augmented as state variables. Based on the observability of the singular system, this paper presents a simplified observability criterion under certain conditions for unknown inputs and uncertain model parameters. When the observability is satisfied, the unknown inputs and the uncertain model parameters are estimated online by the soft sensor using augmented nonlinear singular state observer. The riser reactor of fluid catalytic cracking unit is used as an example for analysis and simulation. With the catalyst circulation rate as the only unknown input without model error, one temperature sensor at the riser reactor outlet will ensure the correct estimation for the catalyst cir-culation rate. However, when uncertain model parameters also exist, additional temperature sensors must be used to ensure correct estimation for unknown inputs and uncertain model parameters of chemical processes.

  10. Seasonal variation of allochthonous and autochthonous energy inputs in an alpine stream

    Directory of Open Access Journals (Sweden)

    Stefano Fenoglio

    2014-10-01

    Full Text Available Despite the enormous importance of alpine streams, information about many aspects of their ecology is still insufficient. Alpine lotic systems differ in many environmental characteristics from those lower down, for example because above tree line streams drain catchments where terrestrial vegetation is scarce and allochthonous organic input is expected to be small. The main objectives of this study were to examine seasonal variation of autochthonous and allochthonous energetic inputs and their relationship with macroinvertebrate communities in the Po river, an alpine non-glacial stream (NW Italy. For one year, samplings were monthly performed in a homogeneous 100 m stream reach for discharge, autochthonous energy input (benthic chlorophyll a, allochthonous energy input (coarse particulate organic matter, abundance and structure of benthic macroinvertebrate community. Chlorophyll a concentrations were in the range of what reported for other alpine streams, but presented a time-lag with respect to what has been reported for glacial-fed mountain rivers. CPOM amounts were lower than those in lowland, forested streams of the same area but exhibited an intriguing, different seasonal variability, probably reported for the first time, with a maximum in spring and a minimum in winter. We collected 29,950 macroinvertebrates belonging to 13 families and 10 orders. Benthic communities were essentially dominated by Ephemeroptera, Plecoptera and Diptera. Scrapers was the most important FFG, but also Shredders were well represented. Relationships between chlorophyll a concentrations, CPOM availability and macroinvertebrate community characteristics were analysed and discussed considering the existence of different top-down or bottom-up regulation mechanisms. This study confirms that benthic algae constitute an essential resource for macroinvertebrates in alpine streams above the tree line but also underlines the importance of terrestrial organic input, a

  11. Estimation of Soil Carbon Input in France: An Inverse Modelling Approach

    Institute of Scientific and Technical Information of China (English)

    J.MEERSMANS; M.P.MARTIN; E.LACARCE; T.G.ORTON; S.DE BAETS; M.GOURRAT; N.P.A.SABY

    2013-01-01

    Development of a quantitative understanding of soil organic carbon (SOC) dynamics is vital for management of soil to sequester carbon (C) and maintain fertility,thereby contributing to food security and climate change mitigation.There are well-established process-based models that can be used to simulate SOC stock evolution; however,there are few plant residue C input values and those that exist represent a limited range of environments.This limitation in a fundamental model component (i.e.,C input) constrains the reliability of current SOC stock simulations.This study aimed to estimate crop-specific and environment-specific plant-derived soil C input values for agricultural sites in Prance based on data from 700 sites selected from a recently established French soil monitoring network (the RMQS database).Measured SOC stock values from this large scale soil database were used to constrain an inverse RothC modelling approach to derive estimated C input values consistent with the stocks.This approach allowed us to estimate significant crop-specific C input values (P < 0.05) for 14 out of 17 crop types in the range from 1.84 ± 0.69 t C ha-1 year-1 (silage corn) to 5.15 ± 0.12 t C ha-1 year-1 (grassland/pasture).Furthermore,the incorporation of climate variables improved the predictions.C input of 4 crop types could be predicted as a function of temperature and 8 as a function of precipitation.This study offered an approach to meet the urgent need for crop-specific and environment-specific C input values in order to improve the reliability of SOC stock prediction.

  12. Beyond Rainfall Multipliers: Describing Input Uncertainty as an Autocorrelated Stochastic Process Improves Inference in Hydrology

    Science.gov (United States)

    Del Giudice, D.; Albert, C.; Reichert, P.; Rieckermann, J.

    2015-12-01

    Rainfall is the main driver of hydrological systems. Unfortunately, it is highly variable in space and time and therefore difficult to observe accurately. This poses a serious challenge to correctly estimate the catchment-averaged precipitation, a key factor for hydrological models. As biased precipitation leads to biased parameter estimation and thus to biased runoff predictions, it is very important to have a realistic description of precipitation uncertainty. Rainfall multipliers (RM), which correct each observed storm with a random factor, provide a first step into this direction. Nevertheless, they often fail when the estimated input has a different temporal pattern from the true one or when a storm is not detected by the raingauge. In this study we propose a more realistic input error model, which is able to overcome these challenges and increase our certainty by better estimating model input and parameters. We formulate the average precipitation over the watershed as a stochastic input process (SIP). We suggest a transformed Gauss-Markov process, which is estimated in a Bayesian framework by using input (rainfall) and output (runoff) data. We tested the methodology in a 28.6 ha urban catchment represented by an accurate conceptual model. Specifically, we perform calibration and predictions with SIP and RM using accurate data from nearby raingauges (R1) and inaccurate data from a distant gauge (R2). Results show that using SIP, the estimated model parameters are "protected" from the corrupting impact of inaccurate rainfall. Additionally, SIP can correct input biases during calibration (Figure) and reliably quantify rainfall and runoff uncertainties during both calibration (Figure) and validation. In our real-word application with non-trivial rainfall errors, this was not the case with RM. We therefore recommend SIP in all cases where the input is the predominant source of uncertainty. Furthermore, the high-resolution rainfall intensities obtained with this

  13. Environmental Transport Input Parameters for the Biosphere Model

    Energy Technology Data Exchange (ETDEWEB)

    M. A. Wasiolek

    2003-06-27

    ], Section 6.2). Parameter values developed in this report, and the related FEPs, are listed in Table 1-1. The relationship between the parameters and FEPs was based on a comparison of the parameter definition and the FEP descriptions as presented in BSC (2003 [160699], Section 6.2). The parameter values developed in this report support the biosphere model and are reflected in the TSPA through the biosphere dose conversion factors (BDCFs). Biosphere modeling focuses on radionuclides screened for the TSPA-LA (BSC 2002 [160059]). The same list of radionuclides is used in this analysis (Section 6.1.4). The analysis considers two human exposure scenarios (groundwater and volcanic ash) and climate change (Section 6.1.5). This analysis combines and revises two previous reports, ''Transfer Coefficient Analysis'' (CRWMS M&O 2000 [152435]) and ''Environmental Transport Parameter Analysis'' (CRWMS M&O 2001 [152434]), because the new ERMYN biosphere model requires a redefined set of input parameters. The scope of this analysis includes providing a technical basis for the selection of radionuclide- and element-specific biosphere parameters (except for Kd) that are important for calculating BDCFs based on the available radionuclide inventory abstraction data. The environmental transport parameter values were developed specifically for use in the biosphere model and may not be appropriate for other applications.

  14. Adaptive control for an uncertain robotic manipulator with input saturations

    Institute of Scientific and Technical Information of China (English)

    Trong-Toan TRAN; Shuzhi Sam GE; Wei HE

    2016-01-01

    In this paper, we address the control problem of an uncertain robotic manipulator with input saturations, unknown input scalings and disturbances. For this purpose, a model reference adaptive control like (MRAC-like) is used to handle the input saturations. The model reference is input to state stable (ISS) and driven by the errors between the required control signals and input saturations. The uncertain parameters are dealt with by using linear-in-the-parameters property of robotic dynamics, while unknown input scalings and disturbances are handled by non-regressor based approach. Our design ensures that all the signals in the closed-loop system are bounded, and the tracking error converges to the compact set which depends on the predetermined bounds of the control inputs. Simulation on a planar elbow manipulator with two joints is provided to illustrate the effectiveness of the proposed controller.

  15. GGDC Productivity Level Database: International Comparisons of Output, Inputs and Productivity at the Industry Level

    OpenAIRE

    Inklaar, Robert; Timmer, Marcel P.

    2008-01-01

    In this paper we introduce the GGDC Productivity Level database. This database provides comparisons of output, inputs and productivity at a detailed industry level for a set of thirty OECD countries. It complements the EU KLEMS growth and productivity accounts by providing comparative levels and follows it in terms of country and industry coverage, variable definition and basic data (O?Mahony and Timmer, 2008). As such, the level and growth accounts can be used together in comparative analyse...

  16. Micromachined dual input axis rate gyroscope

    Science.gov (United States)

    Juneau, Thor Nelson

    The need for inexpensive yet reliable angular rate sensors in fields ranging from automotive to consumer electronics has motivated prolific micromachined rate gyroscope research. The vast majority of research has focused on single input axis rate gyroscopes based upon either translational resonance, such as tuning forks, or structural mode resonance, such as vibrating rings. However, this work presents a novel, contrasting approach based on angular resonance of a rotating rigid rotor suspended by torsional springs. The inherent symmetry of the circular design allows angular rate measurement about two axes simultaneously, hence the name micromachined dual-axis rate gyroscope. The underlying theory of operation, mechanical structure design optimization, electrical interface circuitry, and signal processing are described in detail. Several operational versions were fabricated using two different fully integrated surface micromachining processes as proof of concept. The heart of the dual-axis rate gyroscope is a ˜2 mum thick polysilicon disk or rotor suspended above the substrate by a four beam suspension. When this rotor in driven into angular oscillation about the axis perpendicular to the substrate, a rotation rate about the two axes parallel to the substrate invokes an out of plane rotor tilting motion due to Coriolis acceleration. This tilting motion is capacitively measured and on board integrated signal processing provides two output voltages proportional to angular rate input about the two axes parallel to the substrate. The design process begins with the derivation of gyroscopic dynamics. The equations suggest that tuning sense mode frequencies to the drive oscillation frequency can vastly increase mechanical sensitivity. Hence the supporting four beam suspension is designed such that electrostatic tuning can match modes despite process variations. The electrostatic tuning range is limited only by rotor collapse to the substrate when tuning-voltage induced

  17. Input/output plugin architecture for MDSplus

    Energy Technology Data Exchange (ETDEWEB)

    Stillerman, Joshua, E-mail: jas@psfc.mit.edu [Massachusetts Institute of Technology, 175 Albany Street, Cambridge, MA 02139 (United States); Fredian, Thomas, E-mail: twf@psfc.mit.edu [Massachusetts Institute of Technology, 175 Albany Street, Cambridge, MA 02139 (United States); Manduchi, Gabriele, E-mail: gabriele.manduchi@igi.cnr.it [Consorzio RFX, Euratom-ENEA Association, Corso Stati Uniti 4, Padova 35127 (Italy)

    2014-05-15

    The first version of MDSplus was released in 1991 for VAX/VMS. Since that time the underlying file formats have remained constant. The software however has evolved, it was ported to unix, linux, Windows, and Macintosh. In 1997 a TCP based protocol, mdsip, was added to provide network access to MDSplus data. In 2011 a mechanism was added to allow protocol plugins to permit the use of other transport mechanisms such as ssh to access data users. This paper describes a similar design which permits the insertion of plugins to handle the reading and writing of MDSplus data at the data storage level. Tree paths become URIs which specify the protocol, host, and protocol specific information. The protocol is provided by a dynamically activated shared library that can provide any consistent subset of the data store access API, treeshr. The existing low level network protocol called mdsip, is activated by defining tree paths like “host::/directory”. Using the new plugin mechanism this is re-implemented as an instance of the general plugin that replaces the low level treeshr input/output routines. It is specified by using a path like “mdsip://host/directory”. This architecture will make it possible to adapt the MDSplus data organization and analysis tools to other underlying data storage. The first new application of this, after the existing network protocol is implemented, will be a plugin based on a key value store. Key value stores, can provide inexpensive scalable, redundant data storage. An example of this might be an Amazon G3 plugin which would let you specify a tree path such as “AG3://container” to access MDSplus data stored in the cloud.

  18. Boiling on fins with wire screen of variable effective conductivity

    Directory of Open Access Journals (Sweden)

    Orzechowski Tadeusz

    2017-01-01

    Full Text Available The high scale of integration of modern equipment used for medical, military and other purposes puts heavy demands as regards the removal of great heat fluxes. This can be achieved only in exchangers that apply the phase change phenomena. Among many methods to improve boiling heat transfer, the wire mesh covering demonstrates some advantages due to the possibilities of designing the desired microstructure parameters, availability on the market, and low cost. The wire mesh microstucture with specified geometrical parameters produces anisotropy in conductivity. The different arrangement of the mesh layers relative to the direction of the heat flux is a cause of the change of temperature distribution within the layer. The consequence is a respective change in the discharge conditions of the gas phase and liquid feed. The experiments were conducted on fins covered with a single layer of copper mesh with lumen of 38 % and boiling FC-72 at ambient pressure. Compared with the smooth surface, the wire mesh structures yield an increase in the heat transfer rate at boiling. It is also shown that nucleate boiling is initiated at lower wall superheat. Formulas for longitudinal and perpendicular thermal conductivity are given for different mesh structure arrangements.

  19. Scoliosis Screening in Schools.

    Science.gov (United States)

    New York State Education Dept., Albany. Div. of Pupil Personnel Services.

    The booklet outlines New York state school policy and procedures for screening students for scoliosis, lateral curvature of the spine. It is explained that screening is designed to discover spinal deformities early enough to prevent surgery. Planning aspects, including organizing a planning team for the school district, are discussed. Among…

  20. Screening in multilayer graphene

    NARCIS (Netherlands)

    van Gelderen, R.; Olsen, Richard; de Morais Smith, C.

    2013-01-01

    In this paper, we study the static polarization in ABC-stacked multilayer graphene. Since the density of states diverges for these systems if the number of layers exceeds three, screening effects are expected to be important. In the random phase approximation, screening can be included through the p

  1. Scoliosis Screening in Schools.

    Science.gov (United States)

    New York State Education Dept., Albany. Div. of Pupil Personnel Services.

    The booklet outlines New York state school policy and procedures for screening students for scoliosis, lateral curvature of the spine. It is explained that screening is designed to discover spinal deformities early enough to prevent surgery. Planning aspects, including organizing a planning team for the school district, are discussed. Among…

  2. Colorectal Cancer Screening

    Science.gov (United States)

    ... screening tests have different risks or harms. Screening tests may cause anxiety when you are thinking about or getting ready ... is cancer when there really isn't) can cause anxiety and is usually followed by more tests (such as biopsy ), which also have risks. The ...

  3. Touch screens go optical

    DEFF Research Database (Denmark)

    Hanson, Steen Grüner; Jakobsen, Michael Linde; Pedersen, Henrik Chresten

    2012-01-01

    A simple optical implementation of a touch screen is made possible by disrupting the total internal reflection in a 2D waveguide.......A simple optical implementation of a touch screen is made possible by disrupting the total internal reflection in a 2D waveguide....

  4. Mammography screening in denmark

    DEFF Research Database (Denmark)

    Vejborg, Ilse Merete Munk; Mikkelsen, Ellen Margrethe; Garne, Jens Peter

    2011-01-01

    Mammography screening is offered healthy women, and a high standard on professional and organizational level is mandatory not only in the screening programme but even in the diagnostic work-up and treatment. The main goal is to achieve a substantial reduction in disease specific mortality...

  5. Mammography screening in Denmark

    DEFF Research Database (Denmark)

    Vejborg, Ilse; Mikkelsen, Ellen Margrethe; Garne, Jens Peter

    2011-01-01

    Mammography screening is offered healthy women, and a high standard on professional and organizational level is mandatory not only in the screening programme but even in the diagnostic work-up and treatment. The main goal is to achieve a substantial reduction in disease specific mortality...

  6. EIA screening in Denmark

    DEFF Research Database (Denmark)

    Nielsen, Eskild Holm; Christensen, Per; Kørnøv, Lone

    2005-01-01

    The article points out that EIA screening is effectively a regulatory instrument and it can be a cost-effective instrument with environmental benefits.......The article points out that EIA screening is effectively a regulatory instrument and it can be a cost-effective instrument with environmental benefits....

  7. Sedimentary input of trace metals from the Chukchi Shelf

    Science.gov (United States)

    Aguilar-Islas, A. M.; Seguré, M.; Rember, R.; Nishino, S.

    2014-12-01

    The distribution of trace metals in the Arctic Ocean has implications for their global cycles, yet until recently few trace metal observations were available from this rapidly changing ocean. Profiles of dissolved Fe from recent Japanese field efforts in the Western Canada Basin (2008, 2010) indicate the broad Chukchi Shelf as a source of Fe to the halocline of the Western Canada Basin. Here we present dissolved and particulate data for crustal (Al, Mn, Fe) and non-crustal elements (Co, Cu, Zn) from the productive Chukchi Sea to characterize the sedimentary input of these metals to shelf waters contributing to the halocline layer of the Canada Basin. Water column profiles were collected in late summer 2013 onboard the R/V Mirai at 10 stations from the Bering Strait to the slope, and at a time-series (10 days) station located over the outer shelf. A narrow and variable (5-10 m) benthic boundary layer was sampled at the time-series station with highly elevated dissolved and suspended particulate metal concentrations. High metal concentrations were also observed in the subsurface at a station over Barrow Canyon where mixing is enhanced. Reactivity of suspended particulate metals was determined by the leachable vs. refractory fractions. Metal concentrations were determined by ICP-MS. Trace metal transport from the shelf to the interior will be discussed in context with shelf mechanisms contributing to this export, and to expected future changes in the Arctic Ocean.

  8. Interneurons targeting similar layers receive synaptic inputs with similar kinetics.

    Science.gov (United States)

    Cossart, Rosa; Petanjek, Zdravko; Dumitriu, Dani; Hirsch, June C; Ben-Ari, Yehezkel; Esclapez, Monique; Bernard, Christophe

    2006-01-01

    GABAergic interneurons play diverse and important roles in controlling neuronal network dynamics. They are characterized by an extreme heterogeneity morphologically, neurochemically, and physiologically, but a functionally relevant classification is still lacking. Present taxonomy is essentially based on their postsynaptic targets, but a physiological counterpart to this classification has not yet been determined. Using a quantitative analysis based on multidimensional clustering of morphological and physiological variables, we now demonstrate a strong correlation between the kinetics of glutamate and GABA miniature synaptic currents received by CA1 hippocampal interneurons and the laminar distribution of their axons: neurons that project to the same layer(s) receive synaptic inputs with similar kinetics distributions. In contrast, the kinetics distributions of GABAergic and glutamatergic synaptic events received by a given interneuron do not depend upon its somatic location or dendritic arborization. Although the mechanisms responsible for this unexpected observation are still unclear, our results suggest that interneurons may be programmed to receive synaptic currents with specific temporal dynamics depending on their targets and the local networks in which they operate.

  9. Bayesian robot system identification with input and output noise.

    Science.gov (United States)

    Ting, Jo-Anne; D'Souza, Aaron; Schaal, Stefan

    2011-01-01

    For complex robots such as humanoids, model-based control is highly beneficial for accurate tracking while keeping negative feedback gains low for compliance. However, in such multi degree-of-freedom lightweight systems, conventional identification of rigid body dynamics models using CAD data and actuator models is inaccurate due to unknown nonlinear robot dynamic effects. An alternative method is data-driven parameter estimation, but significant noise in measured and inferred variables affects it adversely. Moreover, standard estimation procedures may give physically inconsistent results due to unmodeled nonlinearities or insufficiently rich data. This paper addresses these problems, proposing a Bayesian system identification technique for linear or piecewise linear systems. Inspired by Factor Analysis regression, we develop a computationally efficient variational Bayesian regression algorithm that is robust to ill-conditioned data, automatically detects relevant features, and identifies input and output noise. We evaluate our approach on rigid body parameter estimation for various robotic systems, achieving an error of up to three times lower than other state-of-the-art machine learning methods.

  10. Reconstruction of organochlorine compound inputs in the Tagus Prodelta.

    Science.gov (United States)

    Mil-Homens, Mário; Vicente, Maria; Grimalt, Joan O; Micaelo, Cristina; Abrantes, Fátima

    2016-01-01

    Twenty century time-resolved variability of riverine deposits of polychlorobiphenyls (PCBs), DDTs, hexachlorocyclohexanes (HCHs) and hexachlorobenzene (HCB) was studied in three (210)Pb dated sediment cores collected in a depositional shelf area adjacent to the Tagus estuary (the Tagus Prodelta). The geographic and temporal distribution patterns were consistent with discharge of these organochlorine compounds (OCs) in the area associated with the Tagus mouth. Their concentrations were not correlated with the sedimentary total organic carbon. The PCB down-core profiles were dominated by CB138 and CB153 (hexa-CBs) congeners followed by CB180 (hepta-CBs). Principal Component Analysis of the congener distributions of these compounds did not define temporal down-core trends. The ratios of DDT metabolites (p,p'-DDE/p,p'-DDT) were consistent with recent DDT inputs into the environment and/or earlier applications and long-term residence in soils/sediments until these were eroded and remobilized. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. Screening for abdominalt aortaaneurisme

    DEFF Research Database (Denmark)

    Lindholt, J S; Juul, Svend; Henneberg, E W

    1997-01-01

    In spite of increasing number of elective resections of abdominal aortic aneurysms (AAA) the mortality or ruptured AAA is increasing. The advantages of elective operations are obvious; the lethality is 2-6% while the lethality of ruptured AAA is 75-95%. However, AAA seldom causes symptoms before...... rupture. Ultrasonographic screening for AAA takes 10 minutes per scan, and the sensitivity and specificity are high. Ultrasonographic screening for AAA is a reliable, safe and inexpensive method for screening, and screening for AAA is discussed worldwide. One point four percent of deaths among men from 65...... to 80 year of age are caused by ruptured AAA. Screening men over 65 for AAA can theoretically prevent a substantial number of deaths. Our calculations predict one prevented AAA-death per 200-300 scans for a cost of about 4000 DKK per saved year of life. However, cost-benefit analyses are based...

  12. Dual arm robotic system with sensory input

    Science.gov (United States)

    Ozguner, U.

    1987-01-01

    The need for dual arm robots in space station assembly and satellite maintainance is of increasing significance. Such robots will be in greater demand in the future when numerous tasks will be assigned to them to relieve the direct intervention of humans in space. Technological demands from these robots will be high. They will be expected to perform high speed tasks with a certain degree of autonomy. Various levels of sensing will have to be used in a sophisticated control scheme. Ongoing research in control, sensing and real-time software to produce a two-arm robotic system than can accomplish generic assembly tasks is discussed. The control hierarchy and the specific control approach are discussed. A decentralized implementation of model-reference adaptive control using Variable Structure controllers and the incorporation of tactile feedback is considered.

  13. Time perspective and perceived risk as related to mammography screening.

    Science.gov (United States)

    Griva, Fay; Anagnostopoulos, Fotios; Potamianos, Gregory

    2013-01-01

    The present study explored the relation of time perspective to perceived risk for breast cancer and mammography screening. Women free from breast cancer (N = 194), eligible for mammography screening in terms of age, completed the Zimbardo Time Perspective Inventory (Zimbardo & Boyd, 1999) and measures of perceived risk, attitude toward performing mammography screening, intention to get a mammogram, and mammography screening behavior. Hierarchical multiple regression analysis revealed that perceived risk of breast cancer (β= .18, p < .01) and intention to be screened (β = .35, p < .01) were significantly associated with mammography screening, after controlling for the effects of sociodemographic (e.g., age, education, and economic level) and health-related variables (e.g., family history of breast cancer and previous benign breast disease). Path analyses including the main psychological variables indicated that perceived risk was indirectly related to intention via attitude (β = .17, p < .01), and to mammography screening through attitude and intention (β = .06, p < .01). Attitude was indirectly related to mammography screening via intention (β = .20, p < .01). Also, a significant indirect association was observed between future orientation and mammography screening, via perceived risk (β = .10, p < .01). Theoretical implications of study findings and suggestions for future research on use of mammography are presented.

  14. Barriers to cancer screening.

    Science.gov (United States)

    Womeodu, R J; Bailey, J E

    1996-01-01

    Many barriers to cancer screening have been summarized and discussed. Barriers have been documented in all patient populations, but some groups such as ethnic minorities and the elderly face unique barriers. The barriers to cancer screening, are multifactorial, but much of the responsibility for change must lie with health care providers and the health care delivery industry. This is not to free the patient of all responsibility, but some significant barriers are beyond their direct control. Take, for example, socioeconomic status, disease knowledge, and culturally related perceptions and myths about cancer detection and treatment. The health care industry must do a better job identifying and overcoming these barriers. The significant effects of provider counseling and advice must not be underestimated. Patients must first be advised, and then further actions must be taken if they reject the screening advice. Did they refuse adherence to recommendations because they do not view themselves as susceptible, because of overwhelming personal barriers, or because of a fatalistic attitude toward cancer detection and treatment? If that is the case, physicians and health care institutions must attempt to change perceptions, educate, and personalize the message so that patients accept their disease susceptibility [table: see text]. Multiple patient and provider risk factors have been identified that can be used to target patients particularly at high risk for inadequate cancer screening and providers at high risk for performing inadequate screening. Research has clearly demonstrated the effectiveness of interventions to improve tracking of patient and physician compliance with screening recommendations. Further research is needed to show the impact of managed-care penetration and payer status on screening efforts, and incentive schemes need to be tested that reward institutions and third-party payers who develop uniform standards and procedures for cancer screening. The

  15. No beneficial effect of preimplantation genetic screening in women of advanced maternal age with a high risk for embryonic aneuploidy

    NARCIS (Netherlands)

    Twisk, Moniek; Mastenbroek, Sebastiaan; Hoek, Annemieke; Heineman, Maas-Jan; van der Veen, Fulco; Bossuyt, Patrick M.; Repping, Sjoerd; Korevaar, Johanna C.

    2008-01-01

    Human preimplantation embryos generated through in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatments show a variable rate of numerical chromosome abnormalities or aneuploidies. Preimplantation genetic screening (PGS) has been designed to screen for aneuploidies in high

  16. No beneficial effect of preimplantation genetic screening in women of advanced maternal age with a high risk for embryonic aneuploidy

    NARCIS (Netherlands)

    Twisk, Moniek; Mastenbroek, Sebastiaan; Hoek, Annemieke; Heineman, Maas-Jan; van der Veen, Fulco; Bossuyt, Patrick M.; Repping, Sjoerd; Korevaar, Johanna C.

    2008-01-01

    Human preimplantation embryos generated through in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatments show a variable rate of numerical chromosome abnormalities or aneuploidies. Preimplantation genetic screening (PGS) has been designed to screen for aneuploidies in high

  17. Cost Analysis of Universal Screening vs. Risk Factor-Based Screening for Methicillin-Resistant Staphylococcus aureus (MRSA)

    Science.gov (United States)

    Roth, Virginia R.; Longpre, Tara; Coyle, Doug; Suh, Kathryn N.; Taljaard, Monica; Ramotar, Karamchand; Forster, Alan

    2016-01-01

    Background The literature remains conflicted regarding the most effective way to screen for MRSA. This study was designed to assess costs associated with universal versus risk factor-based screening for the reduction of nosocomial MRSA transmission. Methods The study was conducted at The Ottawa Hospital, a large multi-centre tertiary care facility with approximately 47,000 admissions annually. From January 2006-December 2007, patients underwent risk factor-based screening for MRSA on admission. From January 2008 to August 2009 universal MRSA screening was implemented. A comparison of costs incurred during risk factor-based screening and universal screening was conducted. The model incorporated probabilities relating to the likelihood of being tested and the results of polymerase chain reaction (PCR) testing with associated effects in terms of MRSA bacteremia and true positive and negative test results. Inputted costs included laboratory testing, contact precautions and infection control, private room costs, housekeeping, and length of hospital stay. Deterministic sensitivity analyses were conducted. Results The risk factor-based MRSA screening program screened approximately 30% of admitted patients and cost the hospital over $780 000 annually. The universal screening program screened approximately 83% of admitted patients and cost over $1.94 million dollars, representing an excess cost of $1.16 million per year. The estimated additional cost per patient screened was $17.76. Conclusion This analysis demonstrated that a universal MRSA screening program was costly from a hospital perspective and was previously known to not be clinically effective at reducing MRSA transmission. These results may be useful to inform future model-based economic analyses of MRSA interventions. PMID:27462905

  18. Cost Analysis of Universal Screening vs. Risk Factor-Based Screening for Methicillin-Resistant Staphylococcus aureus (MRSA.

    Directory of Open Access Journals (Sweden)

    Virginia R Roth

    Full Text Available The literature remains conflicted regarding the most effective way to screen for MRSA. This study was designed to assess costs associated with universal versus risk factor-based screening for the reduction of nosocomial MRSA transmission.The study was conducted at The Ottawa Hospital, a large multi-centre tertiary care facility with approximately 47,000 admissions annually. From January 2006-December 2007, patients underwent risk factor-based screening for MRSA on admission. From January 2008 to August 2009 universal MRSA screening was implemented. A comparison of costs incurred during risk factor-based screening and universal screening was conducted. The model incorporated probabilities relating to the likelihood of being tested and the results of polymerase chain reaction (PCR testing with associated effects in terms of MRSA bacteremia and true positive and negative test results. Inputted costs included laboratory testing, contact precautions and infection control, private room costs, housekeeping, and length of hospital stay. Deterministic sensitivity analyses were conducted.The risk factor-based MRSA screening program screened approximately 30% of admitted patients and cost the hospital over $780 000 annually. The universal screening program screened approximately 83% of admitted patients and cost over $1.94 million dollars, representing an excess cost of $1.16 million per year. The estimated additional cost per patient screened was $17.76.This analysis demonstrated that a universal MRSA screening program was costly from a hospital perspective and was previously known to not be clinically effective at reducing MRSA transmission. These results may be useful to inform future model-based economic analyses of MRSA interventions.

  19. Foraging under competition: the neural basis of input-matching in humans.

    Science.gov (United States)

    Mobbs, Dean; Hassabis, Demis; Yu, Rongjun; Chu, Carlton; Rushworth, Matthew; Boorman, Erie; Dalgleish, Tim

    2013-06-01

    Input-matching is a key mechanism by which animals optimally distribute themselves across habitats to maximize net gains based on the changing input values of food supply rate and competition. To examine the neural systems that underlie this rule in humans, we created a continuous-input foraging task where subjects had to decide to stay or switch between two habitats presented on the left and right of the screen. The subject's decision to stay or switch was based on changing input values of reward-token supply rate and competition density. High density of competition or low-reward token rate was associated with decreased chance of winning. Therefore, subjects attempted to maximize their gains by switching to habitats that possessed low competition density and higher token rate. When it was increasingly disadvantageous to be in a habitat, we observed increased activity in brain regions that underlie preparatory motor actions, including the dorsal anterior cingulate cortex and the supplementary motor area, as well as the insula, which we speculate may be involved in the conscious urge to switch habitats. Conversely, being in an advantageous habitat is associated with activity in the reward systems, namely the striatum and medial prefrontal cortex. Moreover, amygdala and dorsal putamen activity steered interindividual preferences in competition avoidance and pursuing reward. Our results suggest that input-matching decisions are made as a net function of activity in a distributed set of neural systems. Furthermore, we speculate that switching behaviors are related to individual differences in competition avoidance and reward drive.

  20. Does linguistic input play the same role in language learning for children with and without early brain injury?

    Science.gov (United States)

    Rowe, Meredith L; Levine, Susan C; Fisher, Joan A; Goldin-Meadow, Susan

    2009-01-01

    Children with unilateral pre- or perinatal brain injury (BI) show remarkable plasticity for language learning. Previous work highlights the important role that lesion characteristics play in explaining individual variation in plasticity in the language development of children with BI. The current study examines whether the linguistic input that children with BI receive from their caregivers also contributes to this early plasticity, and whether linguistic input plays a similar role in children with BI as it does in typically developing (TD) children. Growth in vocabulary and syntactic production is modeled for 80 children (53 TD, 27 BI) between 14 and 46 months. Findings indicate that caregiver input is an equally potent predictor of vocabulary growth in children with BI and in TD children. In contrast, input is a more potent predictor of syntactic growth for children with BI than for TD children. Controlling for input, lesion characteristics (lesion size, type, seizure history) also affect the language trajectories of children with BI. Thus, findings illustrate how both variability in the environment (linguistic input) and variability in the organism (lesion characteristics) work together to contribute to plasticity in language learning.

  1. Inhibitory Gating of Input Comparison in the CA1 Microcircuit.

    Science.gov (United States)

    Milstein, Aaron D; Bloss, Erik B; Apostolides, Pierre F; Vaidya, Sachin P; Dilly, Geoffrey A; Zemelman, Boris V; Magee, Jeffrey C

    2015-09-23

    Spatial and temporal features of synaptic inputs engage integration mechanisms on multiple scales, including presynaptic release sites, postsynaptic dendrites, and networks of inhibitory interneurons. Here we investigate how these mechanisms cooperate to filter synaptic input in hippocampal area CA1. Dendritic recordings from CA1 pyramidal neurons reveal that proximal inputs from CA3 as well as distal inputs from entorhinal cortex layer III (ECIII) sum sublinearly or linearly at low firing rates due to feedforward inhibition, but sum supralinearly at high firing rates due to synaptic facilitation, producing a high-pass filter. However, during ECIII and CA3 input comparison, supralinear dendritic integration is dynamically balanced by feedforward and feedback inhibition, resulting in suppression of dendritic complex spiking. We find that a particular subpopulation of CA1 interneurons expressing neuropeptide Y (NPY) contributes prominently to this dynamic filter by integrating both ECIII and CA3 input pathways and potently inhibiting CA1 pyramidal neuron dendrites.

  2. Uncertainty of input data for room acoustic simulations

    DEFF Research Database (Denmark)

    Jeong, Cheol-Ho; Marbjerg, Gerd; Brunskog, Jonas

    2016-01-01

    summarizes potential advanced absorption measurement techniques that can improve the quality of input data for room acoustic simulations. Lastly, plenty of uncertain input data are copied from unreliable sources. Software developers and users should be careful when spreading such uncertain input data. More......Although many room acoustic simulation models have been well established, simulation results will never be accurate with inaccurate and uncertain input data. This study addresses inappropriateness and uncertainty of input data for room acoustic simulations. Firstly, the random incidence absorption......-included input data are proven to produce perceptually noticeable changes in the objective parameters, such as the sound pressure level, and loudness-based reverberation time. Surfaces should not be assumed to be locally reacting, particularly for multi-layered absorbers having air cavities. Secondly...

  3. 广西地区中年打鼾者简单三参数筛查OSAHS的多中心研究%Simple three-variable screening tool for identification of patients with obstructive sleep apnea-hypopnea syndrome in middle-aged male snorers from Guangxi region: a multi-center study

    Institute of Scientific and Technical Information of China (English)

    潘凤锦; 刘建红; 谢宇萍; 雷志坚; 梁碧芳; 伍光腾; 周燕; 凌月福; 梁宪梅

    2015-01-01

    Objective To evaluate the correlation between three variables of neck circumference,body mass index (BMI) and Epworth sleepiness scale (ESS) and obstructive sleep apnea-hypopnea syndrome (OSAHS) and the value of three-variable screening tool among snorers in Guangxi region.Methods From May 2009 to June 2014,2 955 middle-aged consecutive patients with snoring were recruited from four hospitals of Guangxi Province.All subjects underwent polysomnography (PSG) and physical examinations including neck circumference,BMI and ESS.The diffrences of neck circumference,BMI and ESS were compared between OSAHS and non-OSAHS groups; the correlation between apnea-hypopnea index (AHI) and neck circumference,BMI and ESS were analyzed.The optimal cutoff point of three variables was selected by SPSS's Optimal Binning methods and screening score was assigned according to the Logistic regression coefficient.The recommended cutoff points were neck circumference ≥ 38.5 cm (3 points),BMI ≥ 25.7 kg/m2 (5 points),ESS ≥ 9 points (1 point) for males and neck circumference ≥ 34.5 cm (5 points),BMI ≥ 24.5 kg/m2 (2 points),ESS ≥ 7 points (1 points) for females.The best integral value was obtained through the receiver operating characteristic (ROC) curve.Results A total of 2 803 subjects fulfilled the study criteria.There were 2 366 males and 437 females.The average values of neck circumference,BMI and ESS were (38.7 ± 3.5) cm,(27.3 ± 3.6) kg/m2 and (8.6 ± 5.4) score respectively.Both males and females had a positive association between AHI and neck circumference,BMI and ESS (r =0.389,0.485,0.293,0.386,0.439 and 0.291 respectively,all P < 0.001).For males,at an integral value ≥6,the sensitivity was 71.4% in the diagnosis of OSAHS,specificity 65.5% and positive predictive value 91.1%.For females,at an integral value ≥3,the sensitivity was 73.3% in the diagnosis of OSAHS,specificity 63.6% and positive predictive value 66.3%.Conclusions In middle-aged snorers in

  4. Colorectal cancer screening

    Institute of Scientific and Technical Information of China (English)

    Ramona M McLoughlin; Colm A O'Morain

    2006-01-01

    Colorectal cancer is a major public health burden worldwide.There is clear-cut evidence that screening will reduce colorectal cancer mortality and the only contentious issue is which screening tool to use.Most evidence points towards screening with fecal occult blood testing.The immunochemical fecal occult blood tests have a higher sensitivity than the guaiac-based tests.In addition,their automation and haemoglobin quantification allows a threshold for colonoscopy to be selected that can be accommodated within individual health care systems.

  5. Screening for asbestbetingede sygdomme?

    DEFF Research Database (Denmark)

    Brauer, Charlotte; Baandrup, Ulrik; Jacobsen, Peter

    2009-01-01

    Screening programs for early detection of asbestos-related cancer have been considered. Conventional X-ray, computed tomography of the thorax, and the biomarkers osteopontin and mesothelin have been critically reviewed in the literature, together with survival data from screening programs...... in asbestos-exposed populations. Data do not currently support implementation of screening programs for asbestos-exposed persons in Denmark. Since mesothelioma is most often an occupational disease, these patients should be admitted to an occupational clinic for aetiological evaluation. Udgivelsesdato: 2009...

  6. Mammography screening in Denmark

    DEFF Research Database (Denmark)

    Vejborg, Ilse; Mikkelsen, Ellen Margrethe; Garne, Jens Peter;

    2011-01-01

    Mammography screening is offered healthy women, and a high standard on professional and organizational level is mandatory not only in the screening programme but even in the diagnostic work-up and treatment. The main goal is to achieve a substantial reduction in disease specific mortality......, but it is not possible to evaluate the effect on mortality until several years later, and continuously monitoring of the quality of all aspects of a screening programme is necessary. Based on other European guidelines, 11 quality indicators have been defined, and guidelines concerning organizational requirements...

  7. Screening for Pancreatic Cancer.

    Science.gov (United States)

    Wada, Keita; Takaori, Kyoichi; Traverso, L William

    2015-10-01

    Neither extended surgery nor extended indication for surgery has improved survival in patients with pancreatic cancer. According to autopsy studies, presumably 90% are metastatic. The only cure is complete removal of the tumor at an early stage before it becomes a systemic disease or becomes invasive. Early detection and screening of individuals at risk is currently under way. This article reviews the evidence and methods for screening, either familial or sporadic. Indication for early-stage surgery and precursors are discussed. Surgeons should be familiar with screening because it may provide patients with a chance for cure by surgical resection.

  8. Linking International Cancer Screening Efforts

    Science.gov (United States)

    Drs. Sudha Sivaram and Steve Taplin speak at the International Cancer Screening Network (ICSN) Meeting, which brings together individuals involved in cancer screening research and cancer screening programs from the ICSN’s member countries.

  9. Cervical cancer - screening and prevention

    Science.gov (United States)

    Cancer cervix - screening; HPV - cervical cancer screening; Dysplasia - cervical cancer screening; Cervical cancer - HPV vaccine ... Almost all cervical cancers are caused by HPV (human papilloma virus). HPV is a common virus that spreads through sexual contact. Certain ...

  10. Screening and diagnosis for HIV

    Science.gov (United States)

    HIV testing; HIV screening; HIV screening test; HIV confirmatory test ... Task Force. Final Update Summary: Human Immunodeficiency Virus (HIV) Infection: Screening. July 2015. www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/ ...

  11. Risks of Lung Cancer Screening

    Science.gov (United States)

    ... Treatment Lung Cancer Prevention Lung Cancer Screening Research Lung Cancer Screening (PDQ®)–Patient Version What is screening? Go ... These are called diagnostic tests . General Information About Lung Cancer Key Points Lung cancer is a disease in ...

  12. Development of ANFIS models for air quality forecasting and input optimization for reducing the computational cost and time

    Science.gov (United States)

    Prasad, Kanchan; Gorai, Amit Kumar; Goyal, Pramila

    2016-03-01

    This study aims to develop adaptive neuro-fuzzy inference system (ANFIS) for forecasting of daily air pollution concentrations of five air pollutants [sulphur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), ozone (O3) and particular matters (PM10)] in the atmosphere of a Megacity (Howrah). Air pollution in the city (Howrah) is rising in parallel with the economics and thus observing, forecasting and controlling the air pollution becomes increasingly important due to the health impact. ANFIS serve as a basis for constructing a set of fuzzy IF-THEN rules, with appropriate membership functions to generate the stipulated input-output pairs. The ANFIS model predictor considers the value of meteorological factors (pressure, temperature, relative humidity, dew point, visibility, wind speed, and precipitation) and previous day's pollutant concentration in different combinations as the inputs to predict the 1-day advance and same day air pollution concentration. The concentration value of five air pollutants and seven meteorological parameters of the Howrah city during the period 2009 to 2011 were used for development of the ANFIS model. Collinearity tests were conducted to eliminate the redundant input variables. A forward selection (FS) method is used for selecting the different subsets of input variables. Application of collinearity tests and FS techniques reduces the numbers of input variables and subsets which helps in reducing the computational cost and time. The performances of the models were evaluated on the basis of four statistical indices (coefficient of determination, normalized mean square error, index of agreement, and fractional bias).

  13. Comparison of Parameter Estimations Using Dual-Input and Arterial-Input in Liver Kinetic Studies of FDG Metabolism.

    Science.gov (United States)

    Cui, Yunfeng; Bai, Jing

    2005-01-01

    Liver kinetic study of [18F]2-fluoro-2-deoxy-D-glucose (FDG) metabolism in human body is an important tool for functional modeling and glucose metabolic rate estimation. In general, the arterial blood time-activity curve (TAC) and the tissue TAC are required as the input and output functions for the kinetic model. For liver study, however, the arterial-input may be not consistent with the actual model input because the liver has a dual blood supply from the hepatic artery (HA) and the portal vein (PV) to the liver. In this study, the result of model parameter estimation using dual-input function is compared with that using arterial-input function. First, a dynamic positron emission tomography (PET) experiment is performed after injection of FDG into the human body. The TACs of aortic blood, PV blood, and five regions of interest (ROIs) in liver are obtained from the PET image. Then, the dual-input curve is generated by calculating weighted sum of both the arterial and PV input curves. Finally, the five liver ROIs' kinetic parameters are estimated with arterial-input and dual-input functions respectively. The results indicate that the two methods provide different parameter estimations and the dual-input function may lead to more accurate parameter estimation.

  14. Analytical delay models for RLC interconnects under ramp input

    Institute of Scientific and Technical Information of China (English)

    REN Yinglei; MAO Junfa; LI Xiaochun

    2007-01-01

    Analytical delay models for Resistance Inductance Capacitance (RLC)interconnects with ramp input are presented for difierent situations,which include overdamped,underdamped and critical response cases.The errors of delay estimation using the analytical models proposed in this paper are less bv 3%in comparison to the SPICE-computed delay.These models are meaningful for the delay analysis of actual circuits in which the input signal is ramp but not ideal step input.

  15. The Application of Input Theory to English Classroom Teaching

    Institute of Scientific and Technical Information of China (English)

    刘坤

    2015-01-01

    Early in the 1980s, Stephen Krashen has proposed a comprehensive and overall Input Theory that explains how the sec⁃ond language is acquired. It is still very referential to present English classroom teaching. In this essay, applications of Input Theo⁃ry to English classroom teaching are developed from six aspects, involving the nature of second language acquisition, comprehensi⁃ble input and so on.

  16. Knowledge Management in Customer Integration: A Customer Input Management System

    OpenAIRE

    Füller, Kathrin; Abud, Elias; Böhm, Markus; Krcmar, Helmut

    2016-01-01

    Customers can take an active role in the innovation process and provide their input (e.g., ideas, idea evaluations, or complaints) to the different phases of the innovation process. However, the management of a huge amount of unstructured customer input poses a challenge for companies. Existing software solutions focus on the early stages of idea management, and neglect the interoperability of tools, sharing, and reuse of customer inputs across innovation cycles and departments. Following the...

  17. Nonparametric Independence Screening in Sparse Ultra-High Dimensional Additive Models

    CERN Document Server

    Fan, Jianqing; Song, Rui

    2011-01-01

    A variable screening procedure via correlation learning was proposed Fan and Lv (2008) to reduce dimensionality in sparse ultra-high dimensional models. Even when the true model is linear, the marginal regression can be highly nonlinear. To address this issue, we further extend the correlation learning to marginal nonparametric learning. Our nonparametric independence screening is called NIS, a specific member of the sure independence screening. Several closely related variable screening procedures are proposed. Under the nonparametric additive models, it is shown that under some mild technical conditions, the proposed independence screening methods enjoy a sure screening property. The extent to which the dimensionality can be reduced by independence screening is also explicitly quantified. As a methodological extension, an iterative nonparametric independence screening (INIS) is also proposed to enhance the finite sample performance for fitting sparse additive models. The simulation results and a real data a...

  18. Macroalgae δ 15 N values in well-mixed estuaries: indicator of anthropogenic nitrogen input or macroalgae metabolism?

    OpenAIRE

    Raimonet, Mélanie; Guillou, Gaël; Mornet, Françoise; Richard, Pierre

    2013-01-01

    International audience; Although nitrogen stable isotope ratio (d15N) in macroalgae is widely used as a bioindicator of anthropogenic nitrogen inputs to the coastal zone, recent studies suggest the possible role of macroalgae metabolism in d15N variability. Simultaneous determinations of d15N of dissolved inorganic nitrogen(DIN) along the landesea continuum, inter-species variability of d15N and its sensitivity to environmental factors are necessary to confirm the efficiency of macroalgae d15...

  19. Macroalgae delta N-15 values in well-mixed estuaries: Indicator of anthropogenic nitrogen input or macroalgae metabolism?

    OpenAIRE

    Raimonet, Melanie; Guillou, Gael; Mornet, Francoise; Richard, Pierre

    2013-01-01

    Although nitrogen stable isotope ratio (delta N-15) in macroalgae is widely used as a bioindicator of anthropogenic nitrogen inputs to the coastal zone, recent studies suggest the possible role of macroalgae metabolism in delta N-15 variability. Simultaneous determinations of delta N-15 of dissolved inorganic nitrogen (DIN) along the land sea continuum, inter-species variability of delta N-15 and its sensitivity to environmental factors are necessary to confirm the efficiency of macroalgae de...

  20. Krashen’s Input Hypothesis and Foreign Language Teaching

    Institute of Scientific and Technical Information of China (English)

    彭辉

    2013-01-01

    Krashen’s Input Hypothesis is one of the most important theories in second language acquisition.The theory provides a good theoretical framework for foreign language teaching in China.The paper introduces the basic ideas of Krashen’s second language acquisition theories,the concept of comprehensible input,and Krashen’s interpretation of input hypothesis.Thus,this paper aims to study Krashen’s Comprehensible Input and attempts to discover how to facilitate China’s foreign language teaching.

  1. Electronically Tunable High Input Impedance Voltage-Mode Multifunction Filter

    Science.gov (United States)

    Chen, Hua-Pin; Yang, Wan-Shing

    A novel electronically tunable high input impedance voltage-mode multifunction filter with single inputs and three outputs employing two single-output-operational transconductance amplifiers, one differential difference current conveyor and two capacitors is proposed. The presented filter can be realized the highpass, bandpass and lowpass functions, simultaneously. The input of the filter exhibits high input impedance so that the synthesized filter can be cascaded without additional buffers. The circuit needs no any external resistors and employs two grounded capacitors, which is suitable for integrated circuit implementation.

  2. The effects of redundant control inputs in optimal control

    Institute of Scientific and Technical Information of China (English)

    DUAN ZhiSheng; HUANG Lin; YANG Ying

    2009-01-01

    For a stabillzable system,the extension of the control inputs has no use for stabllizability,but it is important for optimal control.In this paper,a necessary and sufficient condition is presented to strictly decrease the quadratic optimal performance index after control input extensions.A similar result is also provided for H_2 optimal control problem.These results show an essential difference between single-input and multi-input control systems.Several examples are taken to illustrate related problems.

  3. Characteristic of energy input for laser forming sheet metal

    Institute of Scientific and Technical Information of China (English)

    Liqun Li(李俐群); Yanbin Chen(陈彦宾); Xiaosong Feng(封小松)

    2003-01-01

    Laser forming is a process in which laser-induced thermal deformation is used to form sheet metal withouta hard forming tool or external forces. The energy input of laser beam is the key factor for the temperatureand stress distribution of sheet metal. The purpose of this work is to investigate the influence of energyinput condition on heat input and deformation angle for two-dimension laser forming. Variations in heatinput resulting from material deformation was calculated and discussed in this paper at first. Furthermore,in laser forming under the condition of constant laser energy input, the effects of energy input mode ondeformation angle and temperature field were investigated.

  4. Orthogonal topography in the parallel input architecture of songbird HVC.

    Science.gov (United States)

    Elliott, Kevin C; Wu, Wei; Bertram, Richard; Hyson, Richard L; Johnson, Frank

    2017-06-15

    Neural activity within the cortical premotor nucleus HVC (acronym is name) encodes the learned songs of adult male zebra finches (Taeniopygia guttata). HVC activity is driven and/or modulated by a group of five afferent nuclei (the Medial Magnocellular nucleus of the Anterior Nidopallium, MMAN; Nucleus Interface, NIf; nucleus Avalanche, Av; the Robust nucleus of the Arcopallium, RA; the Uvaeform nucleus, Uva). While earlier evidence suggested that HVC receives a uniformly distributed and nontopographic pattern of afferent input, recent evidence suggests this view is incorrect (Basista et al., ). Here, we used a double-labeling strategy (varying both the distance between and the axial orientation of dual tracer injections into HVC) to reveal a massively parallel and in some cases topographic pattern of afferent input. Afferent neurons target only one rostral or caudal location within medial or lateral HVC, and each HVC location receives convergent input from each afferent nucleus in parallel. Quantifying the distributions of single-labeled cells revealed an orthogonal topography in the organization of afferent input from MMAN and NIf, two cortical nuclei necessary for song learning. MMAN input is organized across the lateral-medial axis whereas NIf input is organized across the rostral-caudal axis. To the extent that HVC activity is influenced by afferent input during the learning, perception, or production of song, functional models of HVC activity may need revision to account for the parallel input architecture of HVC, along with the orthogonal input topography of MMAN and NIf. © 2017 Wiley Periodicals, Inc.

  5. Extinction-Induced Variability in Human Behavior

    Science.gov (United States)

    Kinloch, Jennifer M.; Foster, T. Mary; McEwan, James S. A.

    2009-01-01

    Participants earned points by pressing a computer space bar (Experiment 1) or forming rectangles on the screen with the mouse (Experiment 2) under differential-reinforcement-of-low-rate schedules, followed by extinction. Variability in interresponse time (the contingent dimension) increased during extinction, as for Morgan and Lee (1996);…

  6. REEXAMINING THE ROLE OF INPUT AND THE FEATURES OF OPTIMAL INPUT——(Ⅰ)Role of Input:Why Is Input Essential for Learning to Take Place?

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The paper examines the role of input from a psychologicalperspective.By exploring the relation between language andthought,and the functions of memory,the paper aims to revealthat language,as a medium of thought,cannot be isolatedfrom thought in the thinking process.Therefore,input in thetarget language is to enable the learner to think in that language.Another idea borrowed from Psychology is the phenomenon offorgetting,which is resulted from interference.We argue thatproviding sufficient input for the learner is one of the effectiveways to minimize the degree of interference.The role of input isthen seen as the following:(1)fighting off mother tongueinterference;(2)internalizing L2 grammar;(3)defossilizingand maintaining interlanguage competence;(4)learningvocabulary in context.

  7. Neonatal cystic fibrosis screening test

    Science.gov (United States)

    Cystic fibrosis screening - neonatal; Immunoreactive trypsinogen; IRT test; CF - screening ... Cystic fibrosis is a disease passed down through families. CF causes thick, sticky mucus to build up in ...

  8. Barriers to screening mammography.

    Science.gov (United States)

    Sarma, Elizabeth A

    2015-01-01

    Breast cancer (BRCA) is the second most commonly diagnosed cancer among women in the USA, and mammography is an effective means for the early detection of BRCA. Identifying the barriers to screening mammography can inform research, policy and practice aiming to increase mammography adherence. A literature review was conducted to determine common barriers to screening mammography adherence. PsycINFO and PubMed databases were searched to identify studies published between 2000 and 2012 that examined barriers associated with reduced mammography adherence. Three thematic groups of barriers, based on social ecology, were identified from the literature: healthcare system-level, social and individual-level barriers. Researchers must consider screening behaviour in context and, therefore, should simultaneously consider each level of barriers when attempting to understand screening behaviour and create interventions to increase mammography adherence.

  9. Urine drug screen

    Science.gov (United States)

    Drug screen -- urine ... detect the presence of illegal and some prescription drugs in your urine. Their presence indicates that you recently used these drugs. Some drugs may remain in your system for ...

  10. Cervical Cancer Screening

    Science.gov (United States)

    ... are at increased risk for HPV infections. Other risk factors for cervical cancer include: Giving birth to many children. Smoking cigarettes. Using oral contraceptives ("the Pill"). Having a weakened immune system . Cervical Cancer Screening ...

  11. Rapid Lead Screening Test

    Science.gov (United States)

    ... Vitro Diagnostics Tests Used In Clinical Care Rapid Lead Screening Test Share Tweet Linkedin Pin it More ... reducing the need for a follow-up visit. Lead Risk Links Centers for Disease Control and Prevention ( ...

  12. Congenital hypothyroidism: Screening dilemma

    Directory of Open Access Journals (Sweden)

    Meena P Desai

    2012-01-01

    Full Text Available Primary sporadic congenital hypothyroidism (CH is the most common cause of hypothyroidism infancy early childhood in iodine sufficient region. Screening for neonatal CH began in 1970s. The rationale and reason for neonatal screening for CH (NSCH are well established. It is mandatory in most developed countries along with the screen for metabolic disorder. The possibility of measuring TSH and thyroid hormones in cord blood paved the way for newborn screening (NS for CH. Worldwide it is estimated that 25% of the live born population of 130 million babies undergo NSCH. Klein et al., by 1972 had shown improved CNS prognosis in CH treated by age 3 months. NSCH has largely eradicated the severe irreversible neurodevelopmental damage and reversed the chances of growth failure in infancy and early childhood.

  13. Preconception Carrier Screening

    Science.gov (United States)

    ... and Gaucher disease. People of African, Mediterranean, and Southeast Asian heritage should be offered screening for thalassemias ... Publications Committee Opinions Practice Bulletins Patient Education Green Journal Clinical Updates Practice Management Coding Health Info Technology ...

  14. Prenatal Genetic Screening Tests

    Science.gov (United States)

    ... cells from the fetus or placenta obtained through amniocentesis or chorionic villus sampling (CVS) . FAQ164 “Prenatal Genetic ... should be followed by a diagnostic test with amniocentesis or CVS. The cell-free DNA screening test ...

  15. Pancreatic Cancer Screening.

    Science.gov (United States)

    Das, Koushik K; Early, Dayna

    2017-09-06

    This review describes the rationale for pancreatic cancer screening, outlines groups that are at elevated risk for pancreatic cancer, and summarizes the relative risk in each setting. We also review the methods available for performing pancreatic cancer screening and the recommended screening intervals. Several genetic mutations have been identified that increase the risk for pancreatic cancer. Most are rare, however, and at-risk individuals are most often those with a strong family history of pancreatic cancer (with multiple family members affected) but no identifiable genetic mutation. Known genetic syndromes that increase the risk for pancreatic cancer include hereditary pancreatitis, familial atypical mole and multiple melanoma, Peutz-Jeghers syndrome, Lynch syndrome, BRCA mutations, and Li-Fraumeni syndrome. Genetic testing should be performed in conjunction with genetic counseling, and testing of an affected family member is preferred if possible.The goal of pancreatic cancer screening is to identify pancreatic cancer at an early, curable stage or, ideally, to identify precancerous lesions that can be resected to prevent the development of cancer. Imaging can be performed with either endoscopic ultrasound (EUS) or magnetic resonance cholangiopancreatography (MRCP). These techniques are generally considered to be complementary, although an advantage of EUS is that cysts or solid lesions can be sampled at the time of the procedure. Published results of small cohorts of high-risk patients in pancreatic cancer screening programs have demonstrated a high prevalence of small cystic lesions identified on EUS or MRCP, which often represent side-branch intraductal papillary mucinous neoplasms (IPMN). Knowledge of conditions and syndromes that increase pancreatic cancer risk allows one to identify those patients that may benefit from pancreatic cancer screening. As we gather evidence from large, international, multicenter cohorts of patients at high-risk for pancreatic

  16. Virtual screening against obesity.

    Science.gov (United States)

    Markt, P; Herdlinger, S; Schuster, D

    2011-01-01

    The development of novel drugs against obesity is one of the top priorities of worldwide drug research. In recent years, it has been facilitated by the application of virtual screening methods. In this review, we give a short introduction into obesity-related protein targets and computer-aided drug design techniques. Furthermore, we highlight the most successful virtual screening studies, outline their results, and provide suggestions for future anti-obesity drug development.

  17. Aircrew Screening Instruments Review

    Science.gov (United States)

    2007-09-01

    available tools . Several vendors indicated that they will have new selection instruments available within a few months. These are not listed. As noted...AFCAPS-FR-2011-0012 AIRCREW SCREENING INSTRUMENTS REVIEW Diane L. Damos Damos Aviation Services, Inc...June 2007 – August 2007 4. TITLE AND SUBTITLE Aircrew Screening Instruments Review 5a. CONTRACT NUMBER FA3089-06-F-0385 5b. GRANT NUMBER 5c

  18. The input and output management of solid waste using DEA models: A case study at Jengka, Pahang

    Science.gov (United States)

    Mohamed, Siti Rosiah; Ghazali, Nur Fadzrina Mohd; Mohd, Ainun Hafizah

    2017-08-01

    Data Envelopment Analysis (DEA) as a tool for obtaining performance indices has been used extensively in several of organizations sector. The ways to improve the efficiency of Decision Making Units (DMUs) is impractical because some of inputs and outputs are uncontrollable and in certain situation its produce weak efficiency which often reflect the impact for operating environment. Based on the data from Alam Flora Sdn. Bhd Jengka, the researcher wants to determine the efficiency of solid waste management (SWM) in town Jengka Pahang using CCRI and CCRO model of DEA and duality formulation with vector average input and output. Three input variables (length collection in meter, frequency time per week in hour and number of garbage truck) and 2 outputs variables (frequency collection and the total solid waste collection in kilogram) are analyzed. As a conclusion, it shows only three roads from 23 roads are efficient that achieve efficiency score 1. Meanwhile, 20 other roads are in an inefficient management.

  19. Screening efficiency and screen length of a linear vibrating screen using DEM 3D simulation

    Institute of Scientific and Technical Information of China (English)

    Wang Guifeng; Tong Xin

    2011-01-01

    The effect of screen length on the screening efficiency of particles is studied under various single parameter conditions including frequency,amplitude,vibration angle,and screen inclination.The Discrete Element Method (DEM) has been used to simulate the screening process.A functional relationship between screening efficiency and screen length is established.It is shown that screening efficiency and screen length have a complicated exponential relationship.Relationships between them are profoundly discussed and conclusions are easily drawn:low values of the parameters do not benefit screening; screening efficiency generally increases with screen length; screening efficiency reaches a plateau when these parameters are in range frequently encountered in practical applications.

  20. Modelling Implicit Communication in Multi-Agent Systems with Hybrid Input/Output Automata

    Directory of Open Access Journals (Sweden)

    Marta Capiluppi

    2012-10-01

    Full Text Available We propose an extension of Hybrid I/O Automata (HIOAs to model agent systems and their implicit communication through perturbation of the environment, like localization of objects or radio signals diffusion and detection. To this end we decided to specialize some variables of the HIOAs whose values are functions both of time and space. We call them world variables. Basically they are treated similarly to the other variables of HIOAs, but they have the function of representing the interaction of each automaton with the surrounding environment, hence they can be output, input or internal variables. Since these special variables have the role of simulating implicit communication, their dynamics are specified both in time and space, because they model the perturbations induced by the agent to the environment, and the perturbations of the environment as perceived by the agent. Parallel composition of world variables is slightly different from parallel composition of the other variables, since their signals are summed. The theory is illustrated through a simple example of agents systems.

  1. DYNAMIC DESIGN OF VARIABLE SPEED PLANAR LINKAGES

    Institute of Scientific and Technical Information of China (English)

    Yao Yanan; Yan Hongsen; Zou Huijun

    2005-01-01

    A method for improving dynamic characteristics of planar linkages by actively varying the speed function of the input link is presented. Design criteria and constraints for the dynamic design of variable speed planar linkages are developed. Both analytical and optimization approaches for determining suitable input speed functions to minimize the driving torque, the shaking moment, or both simultaneously of planar linkages, subject to various design requirements and constraints, are derived.Finally, some examples are given to illustrate the design procedure and to verify its feasibility.

  2. Partial Least Squares Regression Variable Screening Studies on Apple Soluble Solids NIR Spectral Detection%苹果可溶性固形物近红外光谱检测的偏最小二乘回归变量筛选研究

    Institute of Scientific and Technical Information of China (English)

    欧阳爱国; 谢小强; 周延睿; 刘燕德

    2012-01-01

    To improve the predictive ability and robustness of the NIR correction model of the soluble solid content (SSC) of apple, the reverse interval partial least squares method, genetic algorithm and the continuous projection method were implemented to select variables of the NIR spectroscopy of the soluble solid content (SSC) of apple, and the partial least squares regression model was established. By genetic algorithm for screening of the 141 variables of the correction model, prediction has the best effect. And compared to the full spectrum correction model, the correlation coefficient increased to 0. 96 from 0. 93, forecast root mean square error decreased from 0. 30°Brix to 0. 23°Brix. This experimental results show that the genetic algorithm combined with partial least squares regression method improved the detection precision of the NIR model of the soluble solid content (SSC) of apple.%为了提高苹果可溶性固形物含量近红外光谱校正模型的预测能力和稳健性,分别采用反向区间偏最小二乘法、遗传算法和连续投影算法,筛选苹果可溶性固形物的近红外光谱变量,并建立了偏最小二乘回归模型.利用遗传算法筛选的141个变量建立的校正模型,预测效果最好,与全谱建立的校正模型比较,预测相关系数,从0.93提高到0.96,预测均方根误差,从0.30°Brix降低到0.23°Brix.实验结果表明遗传算法结合偏最小二乘回归方法,有效地提高了苹果可溶性固形物近红外光谱检测模型的预测精度.

  3. The role of size of input box, location of input box, input method and display size in Chinese handwriting performance and preference on mobile devices.

    Science.gov (United States)

    Chen, Zhe; Rau, Pei-Luen Patrick

    2017-03-01

    This study presented two experiments on Chinese handwriting performance (time, accuracy, the number of protruding strokes and number of rewritings) and subjective ratings (mental workload, satisfaction, and preference) on mobile devices. Experiment 1 evaluated the effects of size of the input box, input method and display size on Chinese handwriting performance and preference. It was indicated that the optimal input sizes were 30.8 × 30.8 mm, 46.6 × 46.6 mm, 58.9 × 58.9 mm and 84.6 × 84.6 mm for devices with 3.5-inch, 5.5-inch, 7.0-inch and 9.7-inch display sizes, respectively. Experiment 2 proved the significant effects of location of the input box, input method and display size on Chinese handwriting performance and subjective ratings. It was suggested that the optimal location was central regardless of display size and input method.

  4. Lung cancer screening: Update

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyea Young [Dept. of Radiology, Center for Lung Cancer, National Cancer Center, Goyang (Korea, Republic of)

    2015-09-15

    Lung cancer is the leading cause of cancer deaths worldwide as well as in Korea. A recent National Lung Screening Trial in U.S. revealed that low-dose CT (LDCT) screening reduced lung cancer specific mortality by 20% in high risk individuals as compared to chest radiograph screening. Based on this evidence, several expert societies in U.S. and Korean multisociety collaborative committee developed guidelines for recommendation of lung cancer screening using annual LDCT in high risk populations. In most of the societies high risk groups are defined as persons aged 55 to 74 years, who are current smokers with history of smoking of more than 30 packs per year or ex-smokers, who quit smoking up to 15 or more years ago. The benefits of LDCT screening are modestly higher than the harms in high risk individuals. The harms included a high rate of false-positive findings, over-diagnosis and radiation-related deaths. Invasive diagnostic procedure due to false positive findings may lead to complications. LDCT should be performed in qualified hospitals and interpreted by expert radiologists. Recently, the American College of Radiology released the current version of Lung cancer CT screening Reporting and Data Systems. Education and actions to stop smoking must be offered to current smokers.

  5. Input dynamics of pesticide transformation products into surface water

    Science.gov (United States)

    Kern, Susanne; Singer, Heinz; Hollender, Juliane; Schwarzenbach, René P.; Fenner, Kathrin

    2010-05-01

    Some pesticide transformation products have been observed to occur in higher concentrations and more frequently than the parent active pesticide in surface water and groundwater. These products are often more mobile and sometimes more stable than the parent pesticide. If they also represent the major product into which the parent substance is transformed, these transformation products may dominate observed pesticide occurrences in surface water and groundwater. Their potential contribution to the overall risk to the aquatic environment caused by the use of the parent pesticide should therefore not be neglected in chemical risk and water quality assessments. The same is true for transformation products of other compound classes that might reach the soil environment, such as veterinary pharmaceuticals. However, the fate and input pathways of transformation products of soil-applied chemicals into surface water are not yet well understood, which largely prevents their appropriate inclusion into chemical risk and water quality assessments. Here, we studied whether prioritization methods based on available environmental fate data from pesticide registration dossiers in combination with basic fate models could help identify transformation products which can be found in relevant concentrations in surface and groundwater and which should therefore be included into monitoring programs. A three-box steady state model containing air, soil, and surface water compartments was used to predict relative inputs of pesticide transformation products into surface waters based on their physico-chemical and environmental fate properties. The model predictions were compared to monitoring data from a small Swiss river located in an intensely agricultural catchment (90 km2) which was flow-proportionally sampled from May to October 2008 and screened for 74 pesticides as well as 50 corresponding transformation products. Sampling mainly occurred during high discharge, but additional samples

  6. The effect of temporal variation on inputs and outputs of future-oriented land use systems in West Africa

    NARCIS (Netherlands)

    Hengsdijk, H.; Keulen, van H.

    2002-01-01

    The (semi-) arid area of West Africa is characterized by erratic rainfall that causes highly variable performances of cropping systems. This creates difficulties in strategic decision-making based on future-oriented production systems. In this paper, the degree of variation in inputs and outputs of

  7. Estimating net present value variability for deterministic models

    NARCIS (Netherlands)

    van Groenendaal, W.J.H.

    1995-01-01

    For decision makers the variability in the net present value (NPV) of an investment project is an indication of the project's risk. So-called risk analysis is one way to estimate this variability. However, risk analysis requires knowledge about the stochastic character of the inputs. For large, long

  8. Air temperature variability in a high-elevation Himalayan catchment

    NARCIS (Netherlands)

    Heynen, Martin; Miles, Evan; Ragettli, Silvan; Buri, Pascal; Immerzeel, Walter W.; Pellicciotti, Francesca

    2016-01-01

    Air temperature is a key control of processes affecting snow and glaciers in high-elevation catchments, including melt, snowfall and sublimation. It is therefore a key input variable to models of land-surface-atmosphere interaction. Despite this importance, its spatial variability is poorly

  9. Sensitivity of Chinese Industrial Wastewater Discharge Reduction to Direct Input Coefficients in an Input-output Context

    Institute of Scientific and Technical Information of China (English)

    TANG Zhipeng; GONG Peiping; LIU Weidong; LI Jiangsu

    2015-01-01

    Industrial wastewater discharge in China is increasing with the country's economic development and it is worthy of concern.The discharge is primarily relevant to the direct discharge coefficient of each sector of the economy,its direct input coefficient and the final demand in input-output models.In this study,we calculated the sensitivity of the reduction in the Chinese industrial wastewater discharge using the direct input coefficients based on the theory of error-transmission in an input-outpnt framework.Using input-output models,we calculated the direct and total industrial wastewater discharge coefficients.Analysis of 2007 input-output data of 30 sectors of the Chinese economy and of 30 provincial regions of China indicates that by lowering their direct input coefficients,the manufacturers of textiles,paper and paper products,chemical products,smelting and metal pressing,telecommunication equipment,computers and other electronic equipment will significantly reduce their amounts of industrial wastewater discharge.By lowering intra-provincial direct input coefficients to industrial sectors themselves of Jiangsu,Shandong and Zhejiang,there will be a significant reduction in industrial wastewater discharge for the country as a whole.Investment in production technology and improvement in organizational efficiency in these sectors and in these provinces can help lessen the direct input coefficients,thereby effectively achieving a reduction in industrial wastewater discharge in China via industrial restructuring.

  10. Carbon balance of renovated grasslands: input- or output-driven?

    Science.gov (United States)

    Choncubhair, Órlaith Ní; Osborne, Bruce; Lanigan, Gary

    2015-04-01

    Temperate grasslands constitute over 30% of the Earth's naturally-occurring biomes and make an important contribution towards the partial mitigation of anthropogenic greenhouse gas emissions by terrestrial ecosystems. In permanent temperate grasslands, biomass production and sward quality can deteriorate over time and periodic renovation activities, involving soil tillage and reseeding, are commonly carried out to halt this decline. Long-term cultivation of agricultural land has been associated with soil aggregate degradation and reduced soil carbon storage. However, the impact of these single tillage disturbances on C cycling in grasslands is less clear. This study evaluated gaseous and dissolved organic carbon (DOC) losses following a single tillage event by subjecting grassland lysimeters with contrasting soil drainage characteristics to simulated conventional inversion or minimum tillage. Field-scale CO2 emissions after conventional tillage were also quantified and empirically modelled over short- and medium-term timeframes to delineate the ecosystem response to environmental variables. Soil moisture was the limiting determinant of ecosystem carbon release following conventional tillage. Freshly-tilled soils were associated with reduced water retention and increased sensitivity to soil moisture, which was particularly pronounced following rewetting events. Significantly elevated but ephemeral CO2 effluxes were detected in the hours following inversion ploughing, however tillage disturbance did not generate significantly enhanced C emission rates in the medium term. Equally, DOC losses were not significantly amplified by conventional tillage compared with conservative minimum tillage and were predominantly controlled by soil drainage across tillage regimes. Our results suggest that a net ecosystem source of 120 to 210 g C m-2 over an approximately two-month period was most likely a consequence of reduced productivity and C input rather than enhanced soil CO2

  11. On the BICM Capacity - Part I: Binary Labelings, Arbitrary Input Distributions, and First-Order Asymptotics

    CERN Document Server

    Alvarado, Alex

    2010-01-01

    In this semitutorial paper (Part I of a two-part paper), the capacity of bit-interleaved coded modulation (BICM) is analyzed. We introduce a general model for BICM which considers all the variables affecting the BICM capacity: the binary labeling, the input distribution, and the signal set. We show that the relation between the BICM capacity and Eb/N0 is not always a one-to-one function, we analyze how to increase the BICM capacity by modifying the input symbol distribution, and we develop first-order asymptotics of the BICM capacity for constellations with arbitrary input distributions, dimensions, mean, variance, and binary labeling. For 8-ary pulse amplitude modulation (PAM) and around Es/N0=0 dB (0.75 bit/symbol), the folded binary code (FBC) results in a higher capacity than the binary reflected gray code (BRGC) and the natural binary code (NBC). For the same SNR, the 1 dB gap between the additive white Gaussian noise (AWGN) capacity and the BICM capacity can be reduced to 0.2 dB if the input symbol dist...

  12. Unraveling the photovoltaic technology learning curve by incorporation of input price changes and scale effects

    Energy Technology Data Exchange (ETDEWEB)

    Yu, C.F.; van Sark, W.G.J.H.M.; Alsema, E.A. [Department of Science, Technology and Society, Copernicus Institute for Sustainable Development and Innovation, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht (Netherlands)

    2011-01-15

    In a large number of energy models, the use of learning curves for estimating technological improvements has become popular. This is based on the assumption that technological development can be monitored by following cost development as a function of market size. However, recent data show that in some stages of photovoltaic technology (PV) production, the market price of PV modules stabilizes even though the cumulative capacity increases. This implies that no technological improvement takes place in these periods: the cost predicted by the learning curve in the PV study is lower than the market one. We propose that this bias results from ignoring the effects of input prices and scale effects, and that incorporating the input prices and scale effects into the learning curve theory is an important issue in making cost predictions more reliable. In this paper, a methodology is described to incorporate the scale and input-prices effect as the additional variables into the one factor learning curve, which leads to the definition of the multi-factor learning curve. This multi-factor learning curve is not only derived from economic theories, but also supported by an empirical study. The results clearly show that input prices and scale effects are to be included, and that, although market prices are stabilizing, learning is still taking place. (author)

  13. Estimation of NMVOC emissions using artificial neural networks and economical and sustainability indicators as inputs.

    Science.gov (United States)

    Stamenković, Lidija J; Antanasijević, Davor Z; Ristić, Mirjana Đ; Perić-Grujić, Aleksandra A; Pocajt, Viktor V

    2016-06-01

    This paper describes the development of an artificial neural network (ANN) model based on economical and sustainability indicators for the prediction of annual non-methane volatile organic compounds (NMVOCs) emissions in China for the period 2005-2011 and its comparison with inventory emission factor models. The NMVOCs emissions in China were estimated using ANN model which was created using available data for nine European countries, which NMVOC emission per capita approximately correspond to the Chinese emissions, for the period 2004-2012. The forward input selection strategy was used to compare the significance of particular inputs for the prediction of NMVOC emissions in the nine selected EU countries and China. The final ANN model was trained using only five input variables, and it has demonstrated similar accuracy in predicting NMVOC emissions for the selected EU countries that were used for the development of the model and then for China for which the input dataset was previously unknown to the ANN model. The obtained mean absolute percentage error (MAPE) values were 8 % for EU countries and 5 % for China. Also, the temporal trend of NMVOC emissions predicted in this study is generally consistent with the trend obtained using inventory emission models. The proposed ANN approach can represent a viable alternative for the prediction of NMVOC emissions at the national level, in particular for developing countries which are usually lacking emission data.

  14. Comparison study of input shaping techniques to control an underactuated flexible link system

    Science.gov (United States)

    Al Hamidi, Yasser; Rakotondrabe, Micky

    2016-05-01

    This paper compares between three different input shaping feedforward techniques, traditional (TIS), extra insensitive (EI), and modified input shaping (MIS), to reduce the vibration of a flexible link QUANSER system. The main challenge is that the system under test is an underactuated system: it has one input and two outputs. This makes the application of the input shaping techniques not utilizable directly. We therefore first propose to use a variable change at the output in order to make the process equivalent to a monovariable system without modification of the behavior and of the objective of the control. The experimental tests demonstrate the efficiency of the technique and the different results from the three control techniques are compared and discussed. It comes out that EI shapers are the most efficient in term of robustness. MIS shaper has a shorter length than that of a corresponding TIS shaper; however both shapers have the same ability of vibration suppression. Also MIS scheme is easier than the traditional scheme because the numerical optimization is unnecessary in the design of the MIS shaper. MIS shaper has an advantage over a TIS corresponding shaper in being capable of suppressing multimode of vibration.

  15. [Organized breast cancer screening].

    Science.gov (United States)

    Rouëssé, Jacques; Sancho-Garnier, Hélèn

    2014-02-01

    Breast screening programs are increasingly controversial, especially regarding two points: the number of breast cancer deaths they avoid, and the problem of over-diagnosis and over-treatment. The French national breast cancer screening program was extended to cover the whole country in 2004. Ten years later it is time to examine the risk/benefit ratio of this program and to discuss the need for change. Like all forms of cancer management, screening must be regularly updated, taking into account the state of the art, new evidence, and uncertainties. All screening providers should keep themselves informed of the latest findings. In the French program, women aged 50-74 with no major individual or familial risk factors for breast cancer are offered screening mammography and clinical breast examination every two years. Images considered non suspicious of malignancy by a first reader are re-examined by a second reader. The devices and procedures are subjected to quality controls. Participating radiologists (both public and private) are required to read at least 500 mammographies per year. The program's national participation rate was 52.7 % in 2012. When individual screening outside of the national program is taken into account (nearly 15 % of women), coverage appears close to the European recommendation of 65 %. Breast cancer mortality has been falling in France by 0.6 % per year for over 30 years, starting before mass screening was implemented, and by 1.5 % since 2005. This decline can be attributed in part to earlier diagnosis and better treatment, so that the specific impact of screening cannot easily be measured. Over-treatment, defined as the detection and treatment of low-malignancy tumors that would otherwise not have been detected in a person's lifetime, is a major negative effect of screening, but its frequency is not precisely known (reported to range from 1 % to 30 %). In view of these uncertainties, it would be advisable to modify the program in order to

  16. Vibration nullification of MEMS device using input shaping

    Science.gov (United States)

    Jordan, Scott; Lawrence, Eric M.

    2003-07-01

    The active silicon microstructures known as Micro-Electromechanical Systems (MEMS) are improving many existing technologies through simplification and cost reduction. Many industries have already capitalized on MEMS technology such as those in fields as diverse as telecommunications, computing, projection displays, automotive safety, defense and biotechnology. As they grow in sophistication and complexity, the familiar pressures to further reduce costs and increase performance grow for those who design and manufacture MEMS devices and the engineers who specify them for their end applications. One example is MEMS optical switches that have evolved from simple, bistable on/off elements to microscopic, freelypositionable beam steering optics. These can be actuated to discrete angular positions or to continuously-variable angular states through applied command signals. Unfortunately, elaborate closed-loop actuation schemes are often necessitated in order to stabilize the actuation. Furthermore, preventing one actuated micro-element from vibrationally cross-coupling with its neighbors is another reason costly closed-loop approaches are thought to be necessary. The Laser Doppler Vibrometer (LDV) is a valuable tool for MEMS characterization that provides non-contact, real-time measurements of velocity and/or displacement response. The LDV is a proven technology for production metrology to determine dynamical behaviors of MEMS elements, which can be a sensitive indicator of manufacturing variables such as film thickness, etch depth, feature tolerances, handling damage and particulate contamination. They are also important for characterizing the actuation dynamics of MEMS elements for implementation of a patented controls technique called Input Shaping«, which we show here can virtually eliminate the vibratory resonant response of MEMS elements even when subjected to the most severe actuation profiles. In this paper, we will demonstrate the use of the LDV to determine how

  17. Combined Adaptive and Predictive Control for a Teleoperation System with Force Disturbance and Input Delay

    Directory of Open Access Journals (Sweden)

    Enrico Franco

    2016-08-01

    Full Text Available This work presents a new discrete-time adaptive-predictive control algorithm for a system with force disturbance and input delay. This scenario is representative of a mechatronic device for percutaneous intervention with pneumatic actuation and long supply lines which is controlled remotely in the presence of an unknown external force resulting from needle-tissue interaction or gravity. The ultimate goal of this research is the robotic-assisted percutaneous intervention of the liver under Magnetic Resonance Imaging (MRI guidance. Since the control algorithm is intended for a digital microcontroller, it is presented in the discrete-time form. The controller design is illustrated for a 1 degree-of-freedom (DOF system and is conducted with a modular approach combining position control, adaptive disturbance compensation, and predictive control. The controller stability is analyzed and the effect of the input delay and of the tuning parameters is discussed. The controller performance is assessed with simulations considering a disturbance representative of needle insertion forces. The results indicate that the adaptive-predictive controller is effective in the presence of a variable disturbance and of a known or variable input delay.

  18. Input--output capital coefficients for energy technologies. [Input-output model

    Energy Technology Data Exchange (ETDEWEB)

    Tessmer, R.G. Jr.

    1976-12-01

    Input-output capital coefficients are presented for five electric and seven non-electric energy technologies. They describe the durable goods and structures purchases (at a 110 sector level of detail) that are necessary to expand productive capacity in each of twelve energy source sectors. Coefficients are defined in terms of 1967 dollar purchases per 10/sup 6/ Btu of output from new capacity, and original data sources include Battelle Memorial Institute, the Harvard Economic Research Project, The Mitre Corp., and Bechtel Corp. The twelve energy sectors are coal, crude oil and gas, shale oil, methane from coal, solvent refined coal, refined oil products, pipeline gas, coal combined-cycle electric, fossil electric, LWR electric, HTGR electric, and hydroelectric.

  19. Comfort constraints. Input for simulation of residents' behavior; Comforthinder. Input bij simulatie van bewonersgedrag

    Energy Technology Data Exchange (ETDEWEB)

    Phaff, H. [TNO Bouw en Ondergrond, Delft (Netherlands)

    2010-04-15

    Buildings in reality, use more energy than predicted. Among many causes, occupant behaviour plays an important role. Better simulation of occupant behaviour, with respect to thermal comfort and energy use of buildings, opens the possibility to design better, comfortable buildings that have lower energy consumption in reality. Thermal discomfort, a dynamical version of Fanger's PPD, is proposed to be used as input to simulate occupant behaviour via a 'flexible task list' and two Markov processes. [Dutch] Simulatie van bewonersgedrag m.b.t. energiegebruik in gebouwen biedt de mogelijkheid om gebouwen en bijbehorende energie installaties zo te ontwerpen dat ze prettiger zijn om in te wonen en te werken. Thermisch discomfort, een dynamische versie van PPD (percentage of dissatisfied persons) wordt hier voorgesteld om via een Markov-proces en een takenlijst bewonersgedrag mee te simuleren.

  20. Fast increases in urban sewage inputs to rivers of Indonesia

    NARCIS (Netherlands)

    Suwarno, D.; Löhr, A.; Kroeze, C.; Widianarko, B.

    2014-01-01

    We present estimates for nitrogen (N) and phosphorus (P) sewage inputs to 19 Indonesian rivers for 1970–2050. Future trends are based on the four scenarios of the Millennium Ecosystem Assessment. Our results indicate a rapid increase in N and P pollution from sewage over time. In 1970, N and P input