Process of globalization and basic traits of Serbian national character

Directory of Open Access Journals (Sweden)

Atlagić Marko

2010-01-01

Full Text Available In contemporary world globalization, along with many perplexities, increasingly takes on the universal/cosmopolitan character in spite of all geographical, national, racial, religious and alignment barriers. Information exchange, scientific achievements and technology are nowadays world process. Economy increasingly becomes global. Serbia and Serbian people have their own specific character, which is defined by three significant characteristics: sovereignty and territorial integrity, aspirations to social justice, the rule of people and democracy. The creators of global society should take into consideration these three important characteristics of Serbian people with which Serbian political elite is to familiarize them, for the sake of more rapid and complete process of integration of Serbs into global processes from both Serbia and its neighboring countries would benefit.

An outline for Serbian political tradition in the work of Slobodan Jovanović

Directory of Open Access Journals (Sweden)

Bazić Jovan R.

2016-01-01

Full Text Available The paper presents considerations of the research on the Serbian political tradition in the work of Slobodan Jovanović (1869-1958, a famous Serbian lawyer, historian, writer and politician, who had a very important role in the development of the Serbian political thought. His work is extensive and varied, but in essence, it relates to the whole of political life in Serbia in the second half of the nineteenth and the first half of the twentieth century. Almost all the elements that make up the Serbian political tradition can be observed in his work. All these elements are contained in the discussion of political institutions in the 19th century Serbia, the rule of the Obrenović dynasty, political parties and party leaders, political ideas and movements in Serbia and Yugoslavia, extreme political behavior and Serbian national character. Jovanović found the origins of Serbian political tradition in the epic poetry and the Kosovo myth, as well as in the poetry of Njegoš. This was a decisive factor in the formation of general ideas about the Serbs as a freedom-loving, heroic and justice-loving people. At the same time, this is where the origins of the idea of Serbs as a disunited nation can be found. Jovanović paid the greatest attention to issues concerning the content of Serbian political tradition, namely: constitutional system, political institutions, parliamentary life, inter-party struggles, political events, the role of the individual in politics and culture, authoritarianism and political violence. He pointed to the political ideas that were coming from the West and which were accepted with mistrust by the patriarchal Serbian society. He appreciated the role of political parties in the democratization of political life, but he also warned of the dangers that threatened national unity: party favouritism and intolerance. In the analyses of the Serbian national character, Jovanović was of the opinion that the Serbs are predominantly a

Affirmation Modality in Bulgarian, Macedonian and Serbian

Directory of Open Access Journals (Sweden)

Marcin Grygiel

2015-06-01

Full Text Available Affirmation Modality in Bulgarian, Macedonian and Serbian In the case of affirmation modality the speakers transform their utterances by stressing or attributing a positive value as an additional component added to the semantic structure of a proposition. This type of affirmative polarization is triggered in opposition to negation or hypothetically negative contexts. The goal of the present paper is twofold: on the one hand to compare and contrast affirmative periphrastic constructions in Bulgarian, Macedonian and Serbian and, on the other hand, to ascertain what these constructions reveal regarding the organization of grammatical categories in general and the status of affirmation modality as a coherent and homogenous category with a linguistic validity.

Translational equivalents and composition of the entries in bilingual English-Serbian dictionaries

Directory of Open Access Journals (Sweden)

Zečević Snežana M.

2013-01-01

Full Text Available The aim of this paper is the analysis of translational eqivalents as well as of the composition of the entries in bilingual English-Serbian dictionaries. It is initially assumed that there are different microstructure and macrostructure of the dictionaries of different volume and purpose, likewise the correspondence of translational equivalents of their entries. The analysis conducted for the requirements of this paper included six randomly chosen lexemes of the English language taken from three bilingual dictionaries that were contrasted with their equivalent lexemes presented in the monolingual English dictionary which was later used for checking. The results of the analysis presented less meaning of the lexemes in Colloquial and Universal English-Serbian Dictionary while the utmost variety of semantic dimensions was noted in Encyclopedic English-Serbian Dictionary which by its quality and organization presents an inexhaustible source of information necessary for translating texts from English to Serbian language.

Etymology of the Serbian language: With a glance at the past and a look into the future

Directory of Open Access Journals (Sweden)

Vlajić-Popović Jasna B.

2017-01-01

Full Text Available After an introductory overview of previous achievements in the field, abroad and at home, during the 19th and 20th centuries, this paper deals with the present state of Serbian etymology (i.e. etymology of the Serbian language among the Serbs which, for several decades now, has been closely related to the Etymological Department of the Serbian Language Institute of the Serbian Academy of Sciences and Arts. Following an explanation of elements of the etymological analysis, we offer a comparison of the methodologies applied in compiling the two dictionaries presently under development at the Department, a thesaurus-type Etimološki rečnik srpskoga jezika (ERSJ - Etymological Dictionary of the Serbian Language and the concise Priručni etimološki rečnik srpskoga jezika (PERSJ - Concise Etymological Dictionary of the Serbian Language. Finally, we present a preliminary projection of the future development of Serbian etymology with a suggested agenda. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 178007: Etimološka istraživanja srpskog jezika i izrada Etimološkog rečnika srpskog jezika

The Indicative and Subjunctive "da"-complements in Serbian A Syntactic-Semantic Approach

Science.gov (United States)

Todorovic, Natasa

2012-01-01

A syntactic-semantic investigation of subjunctive and indicative "da"-complements in Serbian is conducted in this project. After a careful comparison of Serbian sentence constructions with "da"-complements to the equivalent sentence structures in languages of the Balkans as well as other Slavic languages, it is clearly…

Origin of differences between Serbian and Roma children in social intelligence test's achievement

Directory of Open Access Journals (Sweden)

Đigić Gordana

2008-01-01

Full Text Available The goal of the presented research is to identify the origin of differences between Serbian (N=166 and Roma children (N=169 of primary school age in achievement on Modified Rosenzweig Test, used as a measure of social intelligence (Roma children had lower results than Serbian children. Results show that these differences can be partly explained with extreme inviolable socio-economic and cultural status of Roma children. Social intelligence test's scores are significantly correlated with socio-economic and cultural status; this correlation is more apparent in Roma than in Serbian sample. Differences between Serbian and Roma children become less apparent when we control the influence of socio-economic and cultural status. Parent's educational level is recognized as the most important indicator of socio-economic and cultural status. Another way to identify the origin of differences was directed to investigation of adequacy of used test as a measure of social intelligence of Roma children. Our assumption that some items make whole test unfair for Roma children is not confirmed. However, results concerning the relation between experience with particular social situations and success in particular test items, and results concerning the different structures of implicite understanding of social intelligence by Serbian and Roma parents, point out that test key favors responses that Serbian people accept as optimal in task situation, while the responses according to Roma implicite understanding of social intelligence are less valued.

Arhai’s Balkan folktronica: Serbian ethno music reimagined for British market

Directory of Open Access Journals (Sweden)

Medić Ivana

2014-01-01

Full Text Available This article focuses on Serbian composer Jovana Backović and her band/project Arhai, founded in Belgrade in 1998. The central argument is that Arhai made a transition from being regarded a part of the Serbian ethno music scene (which flourished during the 1990s and 2000s to becoming a part of the global world music scene, after Jovana Backović moved from her native Serbia to the United Kingdom to pursue an international career. This move did not imply a fundamental change of her musical style, but a change of cultural context and market conditions that, in turn, affected her cultural identity. [Projekat Ministarstva nauke Republike Srbije, br. 177004: Serbian Musical Identities within Local and Global Frameworks: Traditions, Changes, Challenges

Images of Miloje M. Vasić in Serbian Archaeology

Directory of Open Access Journals (Sweden)

Aleksandar Palavestra

2016-02-01

Full Text Available Miloje M. Vasić, "the first academically educated archaeologist in Serbia", has a strange destiny in the Serbian archaeology. On the one hand, he has been elevated to the post of the "founding father" of the discipline, with almost semidivine status and iconic importance, while on the other hand, his works have been largely unread and neglected. This paradoxical split is the consequence of the fact that Vasić has been postulated as the universal benchmark of the archaeological practice in Serbia, regardless of his interpretation of the past on the grounds of the archaeological record – the essence of archaeology. Strangely, the life and work of Vasić have not been the subject of much writing, apart from several obituaries, two short appropriate texts (Srejović, Cermanović, and rare articles in catalogues and collections dedicated to the research of Vinča (Garašanin, Srejović, Tasić, Nikolić and Vuković. The critical analysis of his whole interpretive constellation, with "The Ionian colony Vinča" being its brightest star, was limited before the World War II to the rare attempts to rectify the chronology and identify the Neolithic of the Danube valley (Fewkes, Grbić, Holste. After the war, by the middle of the 20th century, the interpretation of Vasić has been put to severe criticism of his students (Garašanin, Milojčić, Benac, which led to the significant paradigm shift, the recognition of the importance of the Balkan Neolithic, and the establishment of the culture-historical approach in the Serbian archaeology. However, from this moment on, the reception of Vasić in the Serbian archaeology has taken a strange route: Vasić as a person gains in importance, but his works are neglected, though referred to, but almost in a cultic fashion, without reading or interpreting them. Rare is a paper on the Neolithic of the Central Balkans that does not call upon the name of Vasić and his four- volume "Vinča", in which Neolithic is not

Sentiment Classification of Documents in Serbian: The Effects of Morphological Normalization and Word Embeddings

Directory of Open Access Journals (Sweden)

V. Batanović

2017-11-01

Full Text Available An open issue in the sentiment classification of texts written in Serbian is the effect of different forms of morphological normalization and the usefulness of leveraging large amounts of unlabeled texts. In this paper, we assess the impact of lemmatizers and stemmers for Serbian on classifiers trained and evaluated on the Serbian Movie Review Dataset. We also consider the effectiveness of using word embeddings, generated from a large unlabeled corpus, as classification features.

Reliability and validity of Serbian version of children's dental fear questionnaire

Directory of Open Access Journals (Sweden)

Lalić Maja

2015-01-01

Full Text Available Background/Aim. Dental anxiety leads to avoidance of dental treatment and could lead to impaired oral health. The aim of this study was to determine the reliability of the Serbian version of Children’s Fear Survey Schedule Dental Subscale (CFSS-DS and the relations between dental anxiety and oral health status in a sample of Serbian schoolchildren. Methods. The CFSS-DS scale was translated into Serbian and administered to 231 (12-year old patients of the Pediatric Dental Department, Public Health Center Čukarica, Belgrade. The number of healthy, decayed, missing and filled teeth (DMFT score in children was determined by a clinical exam. Results. The average CFSS-DS score was 26.47 ± 10.33. The girls reported higher anxiety than the boys (p < 0.05. Most common fears were drilling, choking, going to the hospital and anesthesia. Lower CFSS-DS scores were recorded in children with all healthy teeth (p < 0.05. Children with higher CFSS-DS scores mostly visit the dentist due to pain or parental insistence, and those with lower anxiety scores more often visited dentist due to regular check-ups or non-invasive treatments (p < 0.01. A high value of the Cronbach's coefficient of internal consistency (α = 0.88 was found in the entire scale. Conclusion. The Serbian version of CFSS-DS questionnaire is reliable and valid psychometric instrument for evaluation of dental fear in Serbian children. Dental anxiety negatively affects dental attendance and oral health of the examined schoolchildren.

Cultural borrowing - Serbian jogurt between the east and the west

Directory of Open Access Journals (Sweden)

Petrović Snežana M.

2015-01-01

Full Text Available The paper offers an analysis of the cultural borrowing process of the Turkish word yoğurt ‘yogurt’ in Serbian. The study begins with the analysis of the Serbian lexical material from the 19th century, when the word jogurt was marked as an exclusively foreign word. The comparison with the present status of the meaning and usage of the word jogurt in contemporary Serbian, in which the word is part of the standard language, shows two different layers of the borrowing process: the Ottoman Turkish period and the Non-Turkish one. The most recent, Post-Ottoman borrowing layer is illustrated by the usage of jogurt as an element of a proverb that is a calque from the Turk. Sutten ağzı yanan yoğurdu (veya ayranı ufleyerek yer (veya icer “who gets burned by milk, blows into yogurt as well”. Aiming to present a complex process of this cultural borrowing, the data from Serbian is compared to the relevant data from other Balkan and European languages. [Projekat Ministarstva nauke Republike Srbije, br. 178007: Etimološka istraživanja srpskog jezika i izrada Etimološkog rečnika srpskog jezika i br. 178009: Lingvistička istraživanja savremenog srpskog književnog jezika i izrada Rečnika srpskohrvatskog književnog i narodnog jezika SANU

The seals of Karadjordje and of other most prominent leaders in the First Serbian uprising

Directory of Open Access Journals (Sweden)

Atlagić Marko

2007-01-01

Full Text Available The seals which carry the symbols of the First Serbian Uprising appeared quite early, only a few months after its breakout. The seals with the Uprising symbols have a distinct West-European heraldic form. According to their main symbols, these seals belong to either the monogram or the coat-of-arms type. In this paper, the seals of Vozd Karadjordje Proviteljstvujušči Sovjet [Rulling Council], Mladen Milanović, Stojan Čupić Voivode Marko Katić, as well as of Luka Lazarević have been analysed. The central symbols of their seals are a reflection of the then Serbian society (the Serbian lands, the Serbian army, war and justness.

Traditional perception of Greeks in Serbian oral tradition

Directory of Open Access Journals (Sweden)

Konjik Ivana

2006-01-01

Full Text Available Based on material on Greeks from Vuk’s corpus of epic poems, we discuss the construction of ethnic stereotype of Greeks in Serbian language. However, the limitation of the paper’s possible conclusion lies in the nature of the corpus: Vuk had deliberately chosen one material over another, therefore, the corpus relating to Greeks cannot be considered as representative of the whole Serbian folk poems. Therefore, the discussion is limited to certain elements of the stereotype. Nevertheless, these Serbian epic folk poems contain many layers: historical, geographical, sociological, mythological and so on, with a strong foundation in traditional culture; thus, they provide an insight into geo-political situation of the time period, viewpoints, perspectives and experiences of other ethnic groups that Serbs have been into contact with. In particular, the relationship toward Greeks was marked with pronounced patriarchal attitude concerning others: we-others, ours-foreign, good-bad. In this sense, Greeks are portrayed as foreign, and as such, as a potential source of danger. On the other hand, Greeks are Christian Orthodox, which associates them with the category ours. In socio-economic sense, they were traders and wealthy, respected gentlemen. In epical-heroic profile, they were not considered as great heroes, but as "lousy army", and frequently, as unfaithful.

Applied ethnomusicology in Serbia: Politics and policies of Serbian ethnomusicological Society

Directory of Open Access Journals (Sweden)

Dumnić Marija

2012-01-01

Full Text Available This paper deals with ethnomusicological research methodologies, the application of ethnomusicological knowledge outside academic institutions and ideologies which have contributed to ethnomusicological discourses in Serbia. Furthermore, state policy on ethnomusicology and folk music is analyzed. The recent institutionalisation of applied ethnomusicology, i.e. direct ethnomusicological engagement in society, which represents a turning point in the development of ethnomusicology, is particularly emphasized. The difference between contemporary applied ethnomusicology and ethnomusicology is in direct engagement: goals are changed, new strategies of (field- work are introduced, folk music as a political tool is adopted, neutrality of research positions is destabilized, resulting in the emergence of the greatest problem of the discipline - ethics. Applied ethnomusicology in Serbia is especially interesting not only because of local cultural characteristics, but also because of the specific position of Serbian ethnomusicology in the scientific world map. The activities of the Serbian Ethnomusiclogical Society are analyzed as a representative example of successful public engagement. The projects of the Society are classified according to the type of animation (cultural and scientific. The promotion of Serbian folk music, folk music of national minorities and bagpipe-playing revitalization fall into the first category, whereas the second one comprises scientific round tables and the projects dealing with the preservation of Serbian folk music heritage.

The identity controversies about Albanians in Serbian historiography

Directory of Open Access Journals (Sweden)

Đorđević Radomir D.

2013-01-01

Full Text Available The period of our new historiography is mostly burdened by a political discourse of a new establishment, with which the so called period of "brotherhood and unity" began in the former Yugoslavia. In that period of time, but also after the fall of socialism in 1998, fascination with Yugoslavism is still present in the Serbian history. There are almost no textbooks or monographs in which a dogmatic way of thinking is critically reviewed as incomprehensible in our historical science. This is especially related to the problem of Albanian ethnogenesis and their presence in the Balkans. By adopting this imposed opinion that the Albanians are a native population, our historians directly made an immense damage to the Serbian people.

The foundation and work of the Serbian bookstore in Thessaloniki (1890-1896

Directory of Open Access Journals (Sweden)

Zarković Vesna S.

2017-01-01

Full Text Available At the end of the 19th century, diplomatic activity of the Kingdom of Serbia was reinforced. It had especially come to the fore when in 1886 Stojan Novaković was appointed as the deputy in Constantinople. He, as an experienced diplomat, realized the significance of the national idea spreading, and worked actively to that end. After the signing of consular convention, and opening of Serbian consulates in Osman's Empire, conditions for the opening of larger number of schools were created for which the permissions from Turkish authorities were to be acquired. As the number of Serbian pupils increased, and the numbers of schools as well, the issue of books supply was raised, which was not easy at all in that time. Turkish government issued the permission in 1890 that books for Serbian schools should be printed in Constantinople. All books which were to be printed had to pass the censorship of the Educational Committee. Thanks to the reinforced Serbian diplomatic activity in spreading the national idea, some shifts were made, which led representatives of Serbs in Osman's Empire to the idea of opening bookstores. Almost in the same time, bookstores in Priština, Prizren, and Thessaloniki were opened. The bookstore in Thessaloniki bore the official title the Serbian bookstore, and managed to work and survive despite the propaganda of Bulgarian exarchists which tried to thwart its existence frequently by associating with Turkish authorities. The business activity report was filed to the Consulate, which regulated its activities through contracts and measures.

Serbian Volunteers And Russian Revolution Of 1917

Directory of Open Access Journals (Sweden)

Ia. V. Vishniakov

2017-01-01

Full Text Available Using original documents from the Russian State Military Historical Archive, many of which are introduced for the first time, the author reveals details of creation and activities of the Serbian Volunteer Corps formed from captured soldiers and officers of the Austro-Hungarian army inOdessain the Summer 1916. The same autumn it received a baptism of fire in Dobruja fighting in the separate corps of the Russian army under the command of General Zayonchkovsky. The research interest in studying the activities of “national” and "international" military units within the Russian army is connected with the question of expediency and effectiveness of using such forces against those for whom they have not so long ago shed blood. The author, contrary to the popular opinion of Serbian historians, shows that the call to join the First Serbian division did not arouse mass enthusiasm among the prisoners of war both Serbs and representatives of other Yugoslav nations because of well-founded fears for their close relatives living in the Dual Monarchy and a fairly comfortable stay in the Russian captivity. At the same time, the author emphasizes that this military unit, commanded by officers of the Serbian regular army, was considered by the political leadership ofSerbiaas the basis of the future armed forces of the new state ofYugoslavia. The article shows that the events of the Russian Revolution of 1917 influenced the future fate of this military formation. Many of its soldiers later found themselves on different sides of the front in the Russian civil war. A special attention is payed to the interethnic conflict erupted in the corps between the Serbs on the one side and the Croats and Slovenes on the other. The author introduces a significant body of primary documents showing the nuances of relations in the corps between representatives of various Yugoslav nations. The article emphasizes that the relationship of the Serbs, Croats and Slovenes within the

THE PLANNING, PROGRAMING, BUDGETING SYSTEM AND ITS IMPLEMENTATION IN THE SERBIAN MINISTRY OF DEFENSE

Directory of Open Access Journals (Sweden)

Sasa RADUSKI

2010-01-01

Full Text Available The main purpose of introducing the PPBES to the Serbian Ministry of Defense and the Serbian Armed Forces is to provide a rational management of resources and to maintain and build capacity of the Ministry and the Serbian Armed Forces in order to achieve their goals, objectives and missions.Expected results of implementation of the PPBES are reflected in increasing the efficiency and rationalization of the defense planning to a higher level, ensuring compatibility with defense planning and budgeting system of the state and developing a foundation for the effective management of defense resources.

Local Culinary Traditions in the Integration Process of Serbian Food Market with European Union

Directory of Open Access Journals (Sweden)

Tadeusz Czekalski

2017-12-01

Full Text Available Its huge area of cultivated lands (about 5 million hectares makes Serbia stand out against other states of the Balkan region. Food products are still one of the most important components of Serbian export. From 1 March 2012, when Serbia was granted the candidate status to the European Union, making ready to effectively competite with the Member States of the EU, which offer very similar products, became a chance of survival for Serbia’s agricultural and –food industry sector . A chance to increase the absorbency of the internal market creates an increasing culinary awareness in the Serbian society; despite the economic crisis, the Serbians are looking for new, previously unknown tastes or new taglines for tastes already known in Serbian cuisine. The real challenge for Serbian agriculture is the promotion of culinary tourism, which involves exhibiting the ability to compete with other Balkan countries by depicting a more diverse range of attractions. Promotion of the regional products is done by events typical for culinary tourism – festivals, culinary competitions, culinary tourist routes, as well as reconstructions of medieval cuisine. In the realities of Serbia, culinary tourism opens the opportunities for sustainable development of the periphery areas and, at the same time, makes it possible to retain old customs and traditions.

Acquired dyslexia in Serbian speakers with Broca's and Wernicke's aphasia.

Science.gov (United States)

Vuković, Mile; Vuković, Irena; Miller, Nick

2016-01-01

This study examined patterns of acquired dyslexia in Serbian aphasic speakers, comparing profiles of groups with Broca's versus Wernicke's aphasia. The study also looked at the relationship of reading and auditory comprehension and between reading comprehension and reading aloud in these groups. Participants were 20 people with Broca's and 20 with Wernicke's aphasia. They were asked to read aloud and to understand written material from the Serbian adaptation of the Boston Diagnostic Aphasia Examination. A Serbian Word Reading Aloud Test was also used. The people with Broca's aphasia achieved better results in reading aloud and in reading comprehension than those with Wernicke's aphasia. Those with Wernicke's aphasia showed significantly more semantic errors than those with Broca's aphasia who had significantly more morphological and phonological errors. From the data we inferred that lesion sites accorded with previous work on networks associated with Broca's and Wernicke's aphasia and with a posterior-anterior axis for reading processes centred on (left) parietal-temporal-frontal lobes. Copyright © 2016 Elsevier Inc. All rights reserved.

Categories of fruit and vegetables: Attributes and definitions in Serbian

Directory of Open Access Journals (Sweden)

Dilparić Branislava M.

2011-01-01

Full Text Available According to the results of an empirical investigation performed by E. Rosch and K. Mervis (1975, the prototype structures of the categories FRUIT and VEGETABLES, the two superordinate and neighbouring categories with no clear-cut boundaries between them, are formed by family resemblances. Each category has only two attributes ('(part of a plant' and 'edible' which are common to all its members and yet not sufficient to define the category and separate it from other categories of edible (parts of plants. Through the analysis and comparison of a number of definitions for FRUIT and VEGETABLES (obtained in a questionnaire-based survey from a hundred native speakers of Serbian; taken from Lexicography and Conceptual Analysis by A. Wierzbicka; taken from five general dictionaries of the Serbian language, the author of this paper attempts to determine the group of attributes that could play a key role in differentiating the observed categories and to search for the most appropriate way to define the two categories in Serbian which would hopefully be acceptable to both modern (prototype semantics and practical lexicography.

"It All Ended in an Unsporting Way": Serbian Football and the Disintegration of Yugoslavia, 1989-2006

OpenAIRE

Mills, Richard

2009-01-01

Part of a wider examination into football during the collapse of Eastern European Communism between 1989 and 1991, this article studies the interplay between Serbian football and politics during the period of Yugoslavia's demise. Research utilizing interviews with individuals directly involved in the Serbian game, in conjunction with contemporary Yugoslav media sources, indicates that football played an important proactive role in the revival of Serbian nationalism. At the same time the Yugos...

Psychometric Evaluation of the Serbian Version of the Multidimensional Students' Life Satisfaction Scale

Science.gov (United States)

Jovanovic, Veljko; Zuljevic, Dragan

2013-01-01

The main purpose of this study was to evaluate psychometric properties of the Serbian version of the Multidimensional Students' Life Satisfaction Scale (MSLSS). The research was carried out on a sample of 408 high school students (250 females, 158 males), with the mean age 16.6. The Serbian version of the MSLSS has demonstrated good psychometric…

"Serbian" Cultural Events in Buda and Pest between 1860 and 1867

OpenAIRE

Tömöry, Miklós

2015-01-01

"Serbian" Cultural Events in Buda and Pest between 1860 and 1867 Miklós Tömöry (Erasmus Mundus Master "TEMA" - Budapest-Prague-Paris) Abstract Key terms: nationalism, Serbian history, Habsburg Empire, Buda and Pest, urban cultural milieus Situated at the very heart of the Habsburg-ruled Hungarian Kingdom, the twin cities of Buda and Pest played an important role as centres of modern Hungarian (Magyar) and Slavic national movements as well in the course of the nineteenth century. Public and se...

External relationships and marketing practices in Serbian firms: The intangible capital perspective

Directory of Open Access Journals (Sweden)

Mitić Sanja

2015-01-01

Full Text Available This paper presents selected results of research on intangible capital in Serbian firms. The results are part of a broader research project, based on a survey of a sample of Serbian firms. The focus of the project is the various forms of intangible capital, and in this paper we analyse whether and to what degree firms build up their brand capital and increase marketing competencies, and what kind of external relationships they experience. The results provide the first insight into the development of the marketing resources of Serbian firms and show that this element of intangibles is gradually improving but still is at a low level. We find significant differences in the use of marketing resources between firms in regard to their size, international market experience, and ownership type. A more significant development of brand capital, external relationships, and marketing innovations and competencies is found in larger firms, firms with considerable international business experience compared to firms primarily oriented to the domestic market, and in foreign-owned firms. After identifying the strengths and weaknesses of marketing practices in Serbian enterprises we suggest some measures for overcoming the analyzed constraints in order to improve firms’ market positioning, especially in foreign markets.[Projekat Ministarstva nauke Republike Srbije, br. 179062

Common scale features of the recent Greek and Serbian church chant traditions

Directory of Open Access Journals (Sweden)

Peno Vesna

2008-01-01

Full Text Available This paper is an attempt to show the similarity between the Serbian and Greek Post-Byzantine chanting traditions, especially those which relate to the scale organization of modes. Three teachers and reformers from Constantinople, Chrisantos, Gregorios and Chourmousios, established a fairly firm theoretical system for the first time during the long history of church chant. One of the main results of their reform, beside changes relating to neums, was the assignment of strict sizes to the intervals in the natural tonal system. There are three kinds of natural scales: diatonic, chromatic and encharmonic. They all have their place in the Greek Anastasimatarion chant book, whose first edition was prepared by Petar Peloponesios, and later edited by Ionnes Protopsaltes. The first, first plagal and forth plagal modes are diatonic in each of their melos, with very few exceptions; the second and second plagal are soft and hard chromatic, while the third and varis are encharmonic. It is important to note that the Greek chanter is very conscious of the scale foundation of the melody, so he begins to chant the apechima foremost, the intonation formula that comprehends all indisposed details to enter the adequate mode, i. e. melos. One mode could use one sort of scale for all groups of melodies - melos. However, in some modes there are different melos, whose scale organisation is not equal at all. That means that it is not proper to equate mode with scale, but rather to look for the specific scale's shape through the melodies that belong to the melos. The absence of formal Serbian church music theory and, especially, the very conservative way in which church melodies are learnt by ear and by heart, has caused significant gaps, which preclude an adequate approach to the essentional principals of Serbian chant. Over the years many Serbian chanters and musicians have noted down church melodies, especially those from the Octoechos, in F or in G, with the key

Analysis of Serbian Military Riverine Units Capability for Participation in the United Nations Peacekeeping Operations

Directory of Open Access Journals (Sweden)

Slobodan Radojevic

2017-06-01

Full Text Available This paper analyses required personnel, training capacities and equipment for participation in the United Nations peacekeeping operations with the riverine elements. In order to meet necessary capabilities for engagement in United Nations peacekeeping operations, Serbian military riverine units have to be compatible with the issued UN requirements. Serbian Armed Forces have the potential to reach such requirements with the River Flotilla as a pivot for the participation in UN missions. Serbian Military Academy adopted and developed educational and training program in accordance with the provisions and recommendations of the IMO conventions and IMO model courses. Serbian Military Academy has opportunities for education and training military riverine units for participation in the United Nations peacekeeping operations. Moreover, Serbia has Multinational Operations Training Center and Peacekeeping Operations Center certified to provide selection, training, equipping and preparations of individuals and units to the United Nations multinational operations.

The Use of Hungarian and Serbian in the City of Szabadka/Subotica : An Empirical Study

Directory of Open Access Journals (Sweden)

Siarl Ferdinand

2017-09-01

Full Text Available In this study Ferdinand and Komlosi analyze the use of Hungarian and Serbian in the city of Szabadka/Subotica, which is located in the Serbian region of Northern Vajdaság/Vojvodina. A mostly Hungarian speaking city for centuries, Szabadka/Subotica suffered the strong pro-Serbian language policy implemented by the Yugoslavian government from the end of the First World War until the dismantlement of Yugoslavia in the 1990s, which gave Hungarian and other local minority languages a second chance to survive. Nowadays, Szabadka/Subotica is home to two main language groups, southern Slavic languages such a Serbian and Croatian (over sixty per cent and Hungarian (thirty three per cent. Although Ferdinand and Komlosi employed official figures from the Serbian censuses to determine the size of each group, the situation of each language was mapped through empirical observation of language use in informal conversations, in official signage, and in permanent as well as temporary commercial signage. The results show that the role of Serbian (mostly written in Latin script is dominant in almost all spheres of public life and as a lingua franca among various groups. Nevertheless, Hungarian maintains a strong presence in the city, especially in the center and in its northwestern districts. In this paper, Ferdinand and Komlosi aim to contribute to a better general understanding of group dynamics in bilingual settings and, specifically, to provide a clearer view of the language situation in one of the Hungarian-speaking regions lost by the historic Kingdom of Hungary after World War I.

The Serbian panagiarion from Vatopedi

Directory of Open Access Journals (Sweden)

Miljković Bojan

2012-01-01

Full Text Available The panagiarion made out of rhinoceros horn from Vatopedi is one of the few vessels of that kind which originate from the Middle Ages. Its creation can be dated to the end of the 14th, or first half of the 15th century, at the time of very lively relations between this Athonite monastery and the Serbian despotate. [Projekat Ministarstva nauke Republike Srbije, br. 177032: Tradicija, inovacija i identitet u vizantijskom svetu, registrovanom pod brojem

Job satisfaction and gender differences in job satisfaction of teachers in Serbian primary schools

Directory of Open Access Journals (Sweden)

Gligorović Bojana

2014-01-01

Full Text Available This paper aims to examine Serbian primary teachers' job satisfaction as well as the differences in job satisfaction between male and female teachers. The participants were 362 teachers from 57 primary schools in Serbia. Nine dimensions of job satisfaction (Pay, Promotion, Supervision, Fringe Benefits, Contingent Rewards, Operating Procedures, Co-Workers, Nature of Work, Communication were measured. The results indicate that from the dimensions of job satisfaction, Serbian primary teachers are most satisfied with the Nature of work, Communication and Supervision, while the major sources of Serbian primary teachers' job dissatisfaction are Fringe benefits, Pay and Operating procedures. When it comes to the gender difference in job satisfaction, T-test analysis shows slightly higher satisfaction among female teachers, while statistically significant difference exists only in two dimensions: Supervision and Nature of work. Serbian policy makers in the field of education as well as school administrators should pay close attention to teachers' job satisfaction and its improvement considering that it is an essential to the continuing growth of school effectiveness.

Validation of the Serbian adaptation of the Trait Emotional Intelligence Questionnaire-Child Form (TEIQue-CF

Directory of Open Access Journals (Sweden)

Banjac Sonja

2016-01-01

Full Text Available This study investigated trait EI in childhood in a Serbian population by validating a Serbian adaptation of the Trait Emotional Intelligence Questionnaire - Child Form (TEIQue-CF. All 606 participants (Mage = 10.33, SD = 1.55 completed the TEIQue-CF, the Reading the Mind in the Eyes Test (revised version, and the Guess Who peer assessment. Data on academic achievement and truancy were also obtained. The Serbian TEIQue-CF demonstrated robust psychometric properties with satisfactory internal consistencies and extensive evidence of validity in relation to criteria such as emotion recognition, academic grades, truancy rates, and peer ratings. Factor analyses suggested a two-factor solution for the total sample, but a unifactorial structure for the two groups of younger children aged 8 to 9 and 10 to 11. Overall, the results corroborate the validity of the Serbian adaptation and the theoretical and practical importance of the construct of trait EI in children. [Projekat Ministarstva nauke Republike Srbije, br. 179018

Derivational morphology and Serbian EFL learners: Three perspectives on the acquisition process

Directory of Open Access Journals (Sweden)

Dimitrijević-Savić Jovana V.

2011-01-01

Full Text Available Although it has long been an under-researched topic in the field of applied linguistics, morphological knowledge is nowadays regarded as a key component of vocabulary acquisition. The past two decades have witnessed a proliferation of studies of both L1 and L2 learning contexts which shed light on various issues, ranging from morphological processing to receptive/productive knowledge of derivational and inflectional morphology. However, investigations into the acquisition of English morphology by Serbian EFL learners have, to our knowledge, been scarce. The purpose of this paper is, therefore, to explore the productive derivational knowledge of upper-intermediate Serbian EFL learners by means of three different instruments: a test focusing on the knowledge of the four main word family members (nouns, verbs, adjectives, adverbs, a test of cognate and non-cognate derivatives employing six cognate English-Serbian suffixes (-ous/-oz(an, -ize/-izovati, -ation/-acija -ism/-iz(am, -ist/-ist(a, -ity/-itet and a contextualized word-formation skill test. A combination of a qualitative and quantitative approach to data analysis has revealed the difficulties Serbian EFL learners have been experiencing in their morphology/vocabulary classes and it has enabled us to identify common mistakes and weak spots. Our results have pedagogical implications and could be put to use in curriculum design and methodology.

Byzantine influence on the Serbian customary law in the 9th century

Directory of Open Access Journals (Sweden)

Đekić Đorđe N.

2016-01-01

Full Text Available By the 10th century Serbian law recognized the following ways of dispute resolution: revenge and appeasement, and it may be indirectly proved that there was a system of compensation. As punishments, there was banishment into exile, blinding and a death sentence. Since revenge, appeasement and compensation system appear in the pre-state period, while the death penalty has its roots in the blood feud, that indicates they are all of local origin. A question remains about the origin of banishment and blinding a fallen ruler, that is, a rival to the throne. In the first half of the 9th century the Byzantine Empire managed to reinstate its power over the Adriatic Sea, to impose itself over the Serbian states, to Christianise them and to legalise ruling families in the Serbian lands. Suffice to say that in 869 the Serbian states fight wars on the Byzantine side. Origin of influences on the ways of the punishment we seek in Byzantium, or better still, in its legal practice. It has been found that Byzantium used to send their conquered rivals to the throne into exile, punishing them by blinding them, so we draw a conclusion that in the matter of punishment, i.e. in the customary law, it exercised its influence on Serbia.

Lytostratigraphy of the eocene sediments in the Serbian-Macedonian Massif, Republic of Macedonia

OpenAIRE

Stojanova, Violeta; Petrov, Gose; Sijakova-Ivanova, Tena

2017-01-01

This paper presents the lithostratography of the eocene sedimentary series in the Serbian Macedonian massif on the territory of the Republic of Macedonia. Sediments of Eocene age in the Serbian Macedonian massif are represented in the Delchevo, Deve Bair and Strumi ca basin, with the orientation of NW-SE to S-J. With lithostratigraphic studies of eocene sediments in the basins in SMM, 3 superposition lithostratigraphic units (lithozones) were isolated:...

Maritime Training Serbian Autonomous Vessel Protection Detachment

Directory of Open Access Journals (Sweden)

Šoškić Svetislav D.

2014-06-01

Full Text Available The crisis in Somalia has caused appearance of piracy at sea in the Gulf of Aden and the Western Indian Ocean. Somali pirates have become a threat to economic security of the world because almost 30 percent of world oil and 20 percent of global trade passes through the Gulf of Aden. Solving the problem of piracy in this part of the world have included international organizations, institutions, military alliances and the states, acting in accordance with international law and UN Security Council resolutions. The European Union will demonstrate the application of a comprehensive approach to solving the problem of piracy at sea and the crisis in Somalia conducting naval operation — EU NAVFOR Atalanta and operation EUTM under the Common Security and Defense Policy. The paper discusses approaches to solving the problem of piracy in the Gulf of Aden and the crisis in Somalia. Also, the paper points to the complexity of the crisis in Somalia and dilemmas correctness principles that are applied to solve the problem piracy at sea. One of goals is protections of vessels of the World Food Programme (WFP delivering food aid to displaced persons in Somalia. Republic of Serbia joined in this mission and trained and sent one a autonomous team in this military operation for protection WFP. This paper consist the problem of modern piracy, particularly in the area of the Horn of Africa became a real threat for the safety of maritime ships and educational process of Serbian Autonomous vessel protection detachment. Serbian Military Academy adopted and developed educational a training program against piracy applying all the provisions and recommendations of the IMO conventions and IMO model courses for Serbian Autonomous vessel protection detachment.

On social femininatives in Serbian and other Slavic languages

Directory of Open Access Journals (Sweden)

Piper Predrag J.

2016-01-01

Full Text Available Social femininatives, such as Serbian pevačica, učiteljica, upravnica, available in all Slavic languages, have in recent decades become a subject of language policy based on political correctness in the field of gender relations. As part of this language policy, the requirement is put forward of creating feminine neologisms in respect of each masculine noun, designating a profession or social status. The use of the ideological and political criteria in order to change the grammatical structure of the language is typical of more or less all modern Slavic literary languages. A common feature of such language policy is their communicative and grammatical groundlessness. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 178021: Opis i standardizacija savremenog srpskog jezika

The agreement to exchange (permutatio in roman, Byzantine and Serbian mediaeval law

Directory of Open Access Journals (Sweden)

Šarkić Srđan

2015-01-01

Full Text Available The first part of this paper is dedicated to the definition of the agreement to exchange (permutatio and emphasizes the difference, made by Roman lawyers, between exchange (barter and sale (emptio-venditio. The second part analyses Byzantine legal sources that mention this old contract, while the third part is dedicated to Serbian legal documents. In Serbian legal documents the exchange was mentioned as the agreement between a monarch and a monastery or a natural person (individual, concerning donations that were given to the Church.

Low competitiveness of undeveloped areas: 'Narrow throat' of Serbian economy

Directory of Open Access Journals (Sweden)

Vuković Darko

2009-01-01

Full Text Available Inconsistent development policy and traditionally inherited poverty, lack of adequate institutional support and the impact of the transition of Serbian economy are affected the deepening of the parameters of underdeveloped areas in Serbia (South Serbia and Stari Ras and appear of new underdeveloped area (Borski basen. These areas have very low competitiveness and represent bottleneck in the overall competitiveness of Serbian economy. Low Serbian competitiveness caused by many problems (corruption, ineffective legal system and weak protection of contracts, political instability and others, where undeveloped areas represent a special dimension of this problem, with their specific problems, current from almost every social standpoint. This paper explains the specific factors that are the largest source of uncompetitiveness underdeveloped areas, analyzing economic, demographic and socio-political factors, as well as infrastructure, unemployment and education. Results showed that these indicators of competitiveness in underdeveloped areas have far less values than the same indicators in other areas in Serbia. The major causes of low competitiveness of underdeveloped areas (except common with the Republic of Serbia are: low employment, low economic activity, low productivity, low investments, poor educational and demographic structure, underdeveloped infrastructure and socio-political uncertainty. At the end, the paper presents the measures and incentives which increase competitiveness of underdeveloped areas.

The 'long and winding road' of Serbian Law (back to Europe

Directory of Open Access Journals (Sweden)

Pürner Stefan

2014-01-01

Full Text Available In this article, the author analyses the development of law of the SFRJ and the contemporary Serbian Law since the 1980s up to date in selected areas of law, and examines how 'European' it has been throughout this period. In this context, the term 'European' is not to be understood in terms of harmonization with the acquis but rather as a pre-stage in this course which implies a general orientation towards continental European principles and openness towards other European states (in particular, concerning the legal provisions on foreign investment. The analysis has yielded the following conclusions: Under a 'socialist layer' (including, for example, the Constitution of SFRY, the Law on Associated Labour and some provisions of the Criminal Law such as Article 133, the law of the SFRJ in the 1980s was much more European than it is actually known in Western Europe. The examples may be found in the substantive provisions of the 1978 Law on Obligations and in the field of procedural law, particularly in the Law on Civil Procedure was tailored upon the model of the Austrian Civil Procedure Code (called the 'Klein'sche ZPO'. Moreover, in the field of constitutional and administrative judiciary, the SFRY was not only ahead of the other socialist countries but also ahead of a lot of other Western European countries. The opening towards other European states was also reflected in the legislation on foreign investment. In this context, it is worth noting that the SFRJ was the first socialist state which enacted such legislation as early as in 1967. By enacting the Law on the Social Capital and the Law on Enterprises, the SFRY began the transformation of its legal system in 1988, well before the fall of the Berlin wall and considerable earlier than the traditional socialist states. For these reasons, it is justified to say that the law of the SFRY and Serbia during the socialist time was (underneath the layer of socialist law already more European than a

Octoechos: A model and inspiration for Serbian medieval hymnographer

Directory of Open Access Journals (Sweden)

Subotin-Golubović Tatjana

2011-01-01

Full Text Available Octoechos is not merely a musical manual in everyday use during the service in Orthodox Church, but also a comprehensive anthology of church poetry. It contains poetical works of great Byzantine poets, such as John of Damascus, Joseph the Hymnographer, Andrew of Crete. The use of Octoechos during the service is strictly regulated by Typicon. After accepting the Orthodox rite, the Slavs were acquainted with Octoechos which has undoubtedly made a great impression on the attentive audiences present at the service. Octoechos has also influenced the work of medieval Serbian hymnographers all of whom were, as it is well known, pious men. The influence of the poetics typical of hymns of the Octoechos has already been present in the Akoluthia to St. Simeon written by St. Sava. In the hymnographical work of Theodosius this influence is even more present, especially in his Canons on the eight modes (echoi that follow the pattern of the supplicatory canons of the Octoechos. Ephraim, who was the Serbian patriarch in two turns (1375-1379, 1389-1392, wrote his church hymns and prayers following those of the Octoechos. Ephraim composed his stichera dedicated to Christ and Theotokos following the regular change of tones of the Octoechos. The spirit of Octoechos has also marked the work of the last Serbian anonymous hymnographers who wrote Akoluthia to the Translation of the holy relics of Saint Apostle Luke to Serbia and the Paraklisis to St. Luke (mid 15th century.

HOW TO HELP SERBIAN ACADEMIC RESEARCHERS BECOME QUALIFIED ACADEMIC WRITERS FOR INTERNATIONAL READERSHIP

Directory of Open Access Journals (Sweden)

Savka Blagojevic

2011-06-01

Full Text Available Academic writing for international readership is almost always done in English, which in turn, may bring about certain difficulties to non- English academics who are not accustomed to English academic writing norms. Therefore, some linguistic researches, conducted in order to find out the differences between the English academic style and those of non-English ones, are aimed at making non-English academics aware of cross-cultural differences in writing styles and help them modify their own writing style to the requirements of the English academic norms. Thus, in order to help Serbian academics publish internationally, we have initiated a small-scale research by comparing academic re search articles written by English and Serbian academics: thirty from humanities (sociology, psychology and philosophy and thirty from hard sciences (chemistry, geology and environmental pollution. The research presented in the paper focuses the two most important discourse areas in academic articles written by English and Serbian writers: 1. Discourse organization, and 2.Th e choice of rhetoric strategies. The obtained results have pr oven that the two groups of writers display different preferences in their writing styles (which will be presented numerically and on the basis of this fact certain suggestions have been offered, concerning the form that Serbian academic articles should have in order to be published for the international discourse community.

Suretyship in Serbian and comparative legal systems

Directory of Open Access Journals (Sweden)

Pajtić Bojan

2014-01-01

Full Text Available The author has compared the institute of suretyship in Serbian law and other comparative legal systems, both continental and common-law. With the development of economy, these instruments of creditor's protection in the contractual relationship have gained full promotion. The analysis of the similarities and differences in the treatment of suretyship implies a relationship between the European legal systems.

Serbian musical criticism and essay writings during the XIXth and the first half of the XXth century as a subject of musicology research

Directory of Open Access Journals (Sweden)

Vasić Aleksandar N.

2006-01-01

Full Text Available The beginning of 2006 marked two decades since the death of Stana Djurić-Klajn, the first historian of Serbian musical literature. This is the exterior motive for presenting a summary of the state and results of up-to-date musicology research into Serbian musical criticism and essay writings during the XIXth and the first half of the XXth century, alongside the many works dedicated to this branch of national musical history, recently published. In this way the reader is given a detailed background of these studies – mainly the authors' names, books, studies, articles, as well as the problems of this branch of Serbian musicology. The first research is associated with the early years of the XXth century, that is, to the work of bibliography. The pioneer of Serbian ethnomusicology, Vladimir R. Djordjević composed An Essay of the Serbian Musical Bibliography until 1914, noting selected XIXth century examples of Serbian literature on music. Bibliographic research was continued by various institutions and experts during the second half of the XXth century: in Zagreb (today Republic of Croatia; the Yugoslav Institute for Lexicography, Novi Sad (Matica srpska; and Belgrade (Institute for Literature and Art, Slobodan Turlakov, Ljubica Djordjević, Staniša Vojinović etc. In spite of the efforts of these institutions and individuals, a complete analytic bibliography of music in Serbian print of the last two centuries has unfortunately still not been made. The most important contributions to historical research, interpretation and validation of Serbian musical criticism and essay writings were given by Stana Djurić-Klajn, Dr Roksanda Pejović and Dr Slobodan Turlakov. Professor Stana Djurić-Klajn was the first Serbian musicologist to work in this field of Serbian music history. She wrote a significant number of studies and articles dedicated to Serbian musical writers and published their selected readings. Prof. Klajn is the author and editor of the

The use of colour name yellow in English and Serbian phraseologisms

Directory of Open Access Journals (Sweden)

Ratković Jelena R.

2011-01-01

Full Text Available This work shows in what ways the colour name yellow is associated with extra-linguistic reality in the English language. In Serbian translations, we can see many similarities, but also the absolute impossibility of finding either formal or partial correspondents considering metaphorical phraseologisms, or pure idioms, such as for example, those in which this colour is associated with jealousy (He wears yellow stockings or cowardice (He's yellow. The most similar comparisons are those with the sunshine and gold, but there are those that, when translated into Serbian, sound strange, such as yellow as marigold or yellow as a crow's foot. Similarly, it would be strange to use this colour name describing a face (or a whole person looking unhealthy, where in Serbian we use comparison 'yellow as wax'. Metonymically, the colour transfers and labels the whole group of people who supposedly have such a colour, as can be seen from examples high yellow, yellow peril, yellow line. In the Serbian language, people from Asia are also sometimes called the 'yellow', and in Serbian, as well as in the English language, this term has derogatory meaning, but the English language is a bit richer in these phraseologisms, perhaps because people from this continent started to settle in the territory of English-speaking countries earlier than in our country. In the English language, people are qualified by the phraseologisms yellow admiral and yellow dog as well, and those are also pure idioms: it is only possible to translate them into the Serbian language by semantic correspondents - nickname for those who were promoted from captain to admiral and smuggler of alcoholic beverages (or, in another sememe 'the one who is in opposition to the Union of merchants or trade unions'. Common to both languages is the use of this colour name for descriptions of old things (or people, as can be seen from the phraseologisms 'the sere and yellow leaf', 'the paper yellowed with age' and

Logo and semiosis: From an icon sign to the Serbian culture symbol

Directory of Open Access Journals (Sweden)

Bašić Ivana

2012-01-01

Full Text Available A logo is most commonly observed as an emblem with intent to be widely recognized as a permanent symbol, or an icon, additionally permitting correlative meanings within a designative context. In the particular example of the Glossary of Serbian culture logo the opportunities of elements of design (coded iconic message, non-coded iconic message and linguistic message have been analyzed with intention to ascertain communication with future users of the Index conveying the desired message not only about specificities of Serbian culture but also its complexity and unifying nature with the global culture. A logo is observed as a multi-parametric code transcending form a concept of artistic design to a “rhetoric figure” in context of presentation and promotion of Serbian culture. While the art of designing, as a discipline, has the objective of artistic modulation, as well as an aesthetic effect, it also, in this case, represents the form of the governmental strategy in communication with others and formation of the cultural identity of its citizens.

[Anniversaries of the Serbian Medical Society. 60 years since its founding. The dream is fulfilled--the home of the Serbian Medical Society is opened].

Science.gov (United States)

Vuković, Z

1998-01-01

The Serbian Medical Society was founded in Belgrade in 1872, 126 years ago. At that time, Serbia was liberated from the Ottoman domination, and was one of some thirty existing independent states gaining international recognition in 1878. In 1932 an old dream has been fulfilled--on the occasion of the 60th anniversary of the existence and activity of the Serbian Medical Society--the home of Serbian Medical Society was opened. A 30-year-long period in which the building of the Home was one of the main preoccupations and a "guiding light" of Serbian doctors thus ended. Money from charitable funds was used, which caused certain benefactors to be praised as noted personalities. Medical practice in those days was in the state of choice. There were no means for adequate treatment of certain ailments, and therapy without realistic scientific base was given, often covered by fictitious reasons. This was especially true for tuberculosis and cancer. Under the pretext of the introduction of "new therapeutical approaches" into medical practice and treatment, diverse pharmaceutical formulas were introduced without knowledge of their real effect--injections of milk, drug containing animal embrional cells and special attention was paid to transplantation of the sexual glands. The injection of "camphor oil" (5 cc) was thus "recommended, harmless but useless". The treatment of tuberculosis, which domineered the pathology of population, was very chaotic. The greatest number of drugs for "successful cure" were to be found here. Most commotion was caused by the so-called Friedman's cure for tuberculosis which was rejected only after vigorous debates. Our drug "Joannin" on the basis of "the old tuberculine" was also represented in this confusion (and Koch himself was forced to recant it). This medicament was also hailed as "successful cure". The origin of serious scientific efforts, however, are to be found around newly formed journal "Medicinski pregled", which attracted new and

The Western accounts on early Albanian-Serbian interactions and the Kosovo myth

Directory of Open Access Journals (Sweden)

MA. Arben Salihu

2017-06-01

Full Text Available For most of the last millennium, the Balkan region, has been associated with conflicts, wars and instability. Indeed, even today, the situation is very tense. Finding the causes of it, is imperative, but that still does not resolve the deep divisions that are ingrained. The aim of this study is to explore what the Western literature reveals about Balkan enmities, more specifically Albanian-Serbian hostilities throughout past centuries, by focusing at certain periods or events that had a great impact in historical context. The study focuses extensively on Kosovo myth, but also on other specific episodes of Albanian- Serbian interaction, namely Serbian Empire, 1389 Kosovo battle, the description event of Murat I death, and 1806 Serbian Revolution among others. One must bear in mind that Albanians and Serbs presented a united front in certain battles and fights (namely in 1389 and 1806, but later turned guns against each other, resulting in thousands unnecessary deaths. This occurred not because their respective citizens wanted so, but was largely incited through government myths and insincere propaganda. Taking exclusively the Western perspective in this context, whose exploration of events in the Balkans is pretty detailed, only enriches the quality of this study. This research concludes that the region should and must learn from past mistakes that living with myths, wars and propaganda leads to nowhere. The Balkan more than ever needs proactive and creative leaders that shift the minds of Balkan people towards elimination, or at least diminishing, of both physical and mental boundaries against each other.

The presidential elections in Montenegro and the destruction of Serbian national consciousness

Directory of Open Access Journals (Sweden)

Ćurković Miša

2008-01-01

Full Text Available Author uses example of the last presidential elections in Montenegro trying to analyze several factors of transition at the Balkans. The overview of the elections' process shows that international community is the key factor in preventing democratic changes in this small state. The main reason for this attitude is geopolitical rearrangement of the Balkans intended toward oppression and cleaning of Serbian factor in former Yugoslav republics. Finally, author shows that crucial factor of this chain in making of new constellation is business and Serbian political elite, whose behavior displays absolute lack of national consciousness, responsibility and solidarity.

Evaluation of food safety management systems in Serbian dairy industry

Directory of Open Access Journals (Sweden)

Igor Tomašević

2016-01-01

Full Text Available This paper reports incentives, costs, difficulties and benefits of food safety management systems implementation in the Serbian dairy industry. The survey involved 27 food business operators with the national milk and dairy market share of 65 %. Almost two thirds of the assessed dairy producers (70.4 % claimed that they had a fully operational and certified HACCP system in place, while 29.6 % implemented HACCP, but had no third party certification. ISO 22000 was implemented and certified in 29.6 % of the companies, while only 11.1 % had implemented and certified IFS standard. The most important incentive for implementing food safety management systems for Serbian dairy producers was to increase and improve safety and quality of dairy products. The cost of product investigation/analysis and hiring external consultants were related to the initial set-up of food safety management system with the greatest importance. Serbian dairy industry was not greatly concerned by the financial side of implementing food safety management systems due to the fact that majority of prerequisite programmes were in place and regularly used by almost 100 % of the producers surveyed. The presence of competency gap between the generic knowledge for manufacturing food products and the knowledge necessary to develop and implement food safety management systems was confirmed, despite the fact that 58.8 % of Serbian dairy managers had university level of education. Our study brings about the innovation emphasizing the attitudes and the motivation of the food production staff as the most important barrier for the development and implementation of HACCP. The most important identified benefit was increased safety of dairy products with the mean rank scores of 6.85. The increased customer confidence and working discipline of staff employed in food processing were also found as important benefits of implementing/operating HACCP. The study shows that the level of HACCP

The framework for financial stability: Serbian and Ukrainian approaches

Directory of Open Access Journals (Sweden)

Maryna Nikonova

2015-12-01

Full Text Available The development and implementation of any policy require the creation of preconditions for ensuring the independence of such a policy. In order to provide such preconditions, it is necessary to build up an institutional framework and regulate the key principles of development and implementation of an appropriate policy. the macroprudential policy is no exception, either. The macroprudential policy is a new policy area, which aims to identify, analyze and counter risks to the financial system as a whole, as opposed to traditional microprudential regulation and supervision, whose focus is exclusively on the risks of individual institutions. In many countries, the processes of appropriate legislation and building an institutional framework are ongoing. The article is focused on a comparative analysis of the Serbian and the Ukrainian approaches to macroprudential policymaking. The differences and the similarities between the Ukrainian and the Serbian macroprudential policymaking models are generalized.

Study of the influence of the soil and plant natures and pollution on the radon and thoron alpha activities inside various herbal infusions by using solid state nuclear track detectors

International Nuclear Information System (INIS)

Misdaq, M.A.; Ait nouh, F.; Bourzik, W.; Lamine, J.

2000-01-01

Different medicinal plant, spinach and cereal samples have been analysed by using neutron activation analysis and radiochemical separation. The solid state nuclear track detectors technique was utilized for uranium and thorium contents determination as well as for alpha, beta, and gamma dose rates evaluation in various geological and ceramic samples. In this study, uranium and thorium contents have been determined in different plant samples, soils in which they have been grown and in herbal infusions made by boiling the studied plants in potable water by using CR-39 and LR-115 solid state nuclear track detectors. Radon and thoron alpha activities per unit volume inside the plants, soils and herbal infusions studied have been evaluated. The radon transfers between soils and plants as well as between plants and herbal infusions have been investigated. The influence of pollution due to different material dusts on radon and thoron alpha activities inside the plants and their corresponding infusions has been studied. (author)

Weasel claims in advertisements in English and Serbian

Directory of Open Access Journals (Sweden)

Vidaković Mirna M.

2017-01-01

Full Text Available This paper investigates the use of weasel claims in advertisements in English and Serbian. Weasel claims represent a form of covert communication and are characterized by the use of deliberately vague and misleading language. In the advertising discourse, this linguistic device helps advertisers to deal with sensitive issues, overcome consumers' distrust and thus influence their behavior. The research has been conducted on a corpus of 100 advertisements that belong to various categories, such as cars, cleaning products, cosmetics, drinks, food, etc., published in printed magazines and online sources from the year 2000 onwards. The aim of the analysis is to identify manifestations of weasel claims in the corpus, establish similarities and differences regarding their use in the given languages, and show how they influence the interpretation of the advertising message and create consumer behavioral patterns. Descriptive and contrastive analyses have been employed in the research. The study also draws on Grice's Cooperative Principle. The results will show that this deceptive tool is widespread in both languages and that its use in the advertising discourse in Serbian requires further research.

Empirically based solutions for the Serbian adaptation of a parent report inventory used in the assessment of child language development

Directory of Open Access Journals (Sweden)

Anđelković Darinka

2017-01-01

Full Text Available The study is aimed at providing empirical basis for the adaptation of the MacArthur-Bates’ Communicative Development Inventories (CDIs for Serbian language, a parent report instrument for the language development assessment. Two sources of data were used in order to provide the basis for selection of items and evaluation of their linguistic, cultural and developmental validity: a. Serbian Corpus of Early Child Language (SCECL, and b. focus groups with experts and parents/caregivers. Exploration of the frequency of words/forms in Serbian child language and the qualitative analysis of focus groups discussions provided criteria for selection/adjustment of items in the course of inventory adaptation. The results also revealed that parents are naturally more focused on semantic and communicational aspects of utterances, and insufficiently aware of formal properties of their children’s production. The paper presents significant changes and modifications of the instrument in the course of its adaptation for Serbian, which is a step closer to the final aim - providing a standardized instrument for the assessment of language development in Serbian. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. ON179033, Grant no. ON179034 and Grant no. III47008

A Balkan-style French revolution?: The 1804 Serbian Uprising in European perspective

Directory of Open Access Journals (Sweden)

Bataković Dušan T.

2005-01-01

Full Text Available The Serbian uprising of 1804-13, initially a peasant rebellion against abuses of power by local janissaries, turned into a national and social revolution from 1806. During its second phase (late 1806 - early 1807, Serbian insurgents openly proclaimed their demand for independence. Encouraged by their military achievements, the insurgent leaders began to seek wider Balkan support for their struggle against Ottoman domination. Although its political claims were a mixture of modern national and romantic historic rights, the uprising gave hope to all Balkan Christians that the Ottoman defeat was an achievable goal. For the Balkan nations it was a French Revolution adapted to local conditions: the principle of popular sovereignty was opposed to the principle of legitimism; a new peasant-dominated society was created in which, due to the lack of the aristocracy and well-established middle classes, agrarian egalitarianism was combined with the rising aspirations of a modern nation. Its long-term effects on the political and social landscape of the whole region justified the assessment of the eminent German historian Leopold von Ranke who described the uprising, by analogy with the French example, as the Serbian Revolution.

The influence of the soil and plant natures and pollution on the radon and thoron alpha-activities inside various herbal infusions by using solid state nuclear track detectors

International Nuclear Information System (INIS)

Misdaq, M.A.; Nouh, F.A.; Bourzik, W.

2001-01-01

Uranium and thorium contents were determined in samples of various plants in the soils in which the plants were grown, and in herbal infusions made by boiling the plants in potable water, using CR-39 and LR-115 solid state nuclear track detectors. In addition, radon and thoron alpha-activities per unit volume inside the plants, soils and herbal infusions were measured. These measurements were completed by an investigation of the radon transfer between soils and plants and that between plants and herbal infusions, and also by the investigation of the influence of pollution due to different material dusts on the radon and thoron alpha activities inside the plants and their infusions. (author)

Serbian SNF Repatriation Operation. Issues, Solving, Lesson

Energy Technology Data Exchange (ETDEWEB)

Smirnov, A. [Research and Development Company ' Sosny' , Moscow (Russian Federation)

2011-07-01

reactor site location all types of transport means were used in this transportation: empty casks were delivered by road and air, SNF was transported by road, rail and sea. The success of the Serbian Project is the result of professionalism and efficient cooperation of many national and international organizations. The lessons learned are useful and could be used in other projects of fuel removal and decommission of nuclear facilities. (author)

The rise and growth of Serbian banking until World war I: Part one: Creation of preconditions for the rise of Serbian banking until 1878

Directory of Open Access Journals (Sweden)

Stojanović Biljana

2016-01-01

Full Text Available The development of Serbian banking during the 19th century was a gradual process that underwent two distinctive stages with the turning point in 1878 when Serbia became an independent state by the international agreement concluded at the Berlin Peace Conference. In the first stage, until 1878, the vassal state of Serbia had been introducing necessary political, economic and institutional preconditions for the rise of banking that led to the creation of the first organized credits and banks. At the end of this stage, there were two types of proper banks: state banks and privately-owned banks. Since the authorities of the vassal state of Serbia played a key role in preparing institutional framework for the banking operations and in organizing the first credit facilities, it could be argued that Serbian banking arose in the 19th century as a result of both state-backed and growthinduced processes.

A CRITICAL REVIEW OF THE ENGLISH LANGUAGE TEXTBOOK WITH EMPHASIS ON ENGLISH-SERBIAN GLOSSARY

OpenAIRE

Иван Књижар

2012-01-01

In this paper we made a critical review of textbook Messages 1 with emphasis on English-Serbian glossary. Since this textbook is intended for pupils of 5th grade, we examined its appropriateness for this age group. In addition, we did lexical and semantic analysis of a glossary that is incorporated in the textbook. Messages 1 is extraordinarily designed textbook. It is alsko uitable for pupils of 5th grade whose first language is not English. In terms of the English-Serbian glossary, there is...

Serbian music criticism in the first half of the twentieth century: Its canon, its method and its educational role

Directory of Open Access Journals (Sweden)

Vasić Aleksandar

2008-01-01

Full Text Available Serbian music criticism became a subject of professional music critics at the beginning of the twentieth century, after being developed by music amateurs throughout the whole previous century. The Serbian Literary Magazine (1901- 1914, 1920-1941, the forum of the Serbian modernist writers in the early 1900s, had a crucial role in shaping the Serbian music criticism and essayistics of the modern era. The Serbian elite musicians wrote for the SLM and therefore it reflects the most important issues of the early twentieth century Serbian music. The SLM undertook the mission of educating its readers. The music culture of the Serbian public was only recently developed. The public needed an introduction into the most important features of the European music, as well as developing its own taste in music. This paper deals with two aspects of the music criticism in the SLM, in view of its educational role: the problem of virtuosity and the method used by music critics in this magazine. The aesthetic canon of the SLM was marked by decisively negative attitude towards the virtuosity. Mainly concerned by educating the Serbian music public in the spirit of the highest music achievements in Europe, the music writers of the SLM criticized both domestic and foreign performers who favoured virtuosity over the 'essence' of music. Therefore, Niccolò Paganini, Franz Liszt, and even Peter Tchaikowsky with his Violin concerto became the subject of the magazine's criticism. However their attitude towards the interpreters with both musicality and virtuoso technique was always positive. That was evident in the writings on Jan Kubelík. This educational mission also had its effect on the structure of critique writings in the SLM. In their wish to inform the Serbian public on the European music (which they did very professionally, the critics gave much more information on biographies, bibliographies and style of the European composers, than they valued the interpretation

Serbian migration policy concerning irregular migration and asylum in the context of the EU integration process

Directory of Open Access Journals (Sweden)

Marta Stojić-Mitrović

2016-02-01

Full Text Available In this paper I would like to present Serbian migration policy concerning irregular migration and asylum in the context of the attempts of the Serbian state to become a member of the European Union. I would describe the history of the asylum system prior and after the implementation of the independent asylum system in Serbia in 2008. My presentation of the Serbian migration policy would be channelled by the analysis of some particular political issues, such as the externalization of the EU borders’ control, as well as some relevant elements of the European integration process, like visa liberalization. The second, more culturally specific dimension of the issue would be accessed through the demonstration of both legislative and public conceptualizations of the irregular migrants, asylum seekers and refugees in Serbia.

Encouraging initiative, cooperation and creativity in teaching Serbian language and literature

Directory of Open Access Journals (Sweden)

Stevanović Jelena

2013-01-01

Full Text Available Instruction in Serbian language and literature serves to prepare and in a certain way enable the students to follow other school subjects, which points to its special relevance for total education. Unfortunately, research results indicate that students’ knowledge in this field is not entirely satisfactory. One of the reasons maybe the fact that this knowledge is not sufficiently used in practice, which can have an unfavourable impact on students’ response to more and more complex demands set by the education system of the 21st century. Additionally, the problem can also be related to the fact that dogmatic-reproductive and reproductive-explicative methodical approaches are still used in the classes of Serbian language and literature, while less attention is paid to creative work, cooperative learning and students’ initiative, the competences that should be developed first and foremost during the initial education. This paper aims at pointing to the methods and procedures that contribute to the encouragement of initiative, cooperation and creativity in primary school students in the instruction in Serbian language and literature. Among other tings, we point out to the innovation of the drama method as an integral approach to teaching contents, which serves to adopt more quality knowledge via focused role-playing activities and drama techniques, primarily in the field of literature, and enables the durability and quality of the aesthetic perception and the reception of literature. It is also pointed to the fact that instruction that includes creative work, initiative and cooperative relations enhances student competences not only in knowledge and skills in Serbian language and literature, but also at the level of emotional and social relations between students. [Projekat Ministarstva nauke Republike Srbije, br. 47008: Unapređivanje kvaliteta i dostupnosti obrazovanja u procesima modernizacije Srbije i br. 179034: Od podsticanja inicijative

Phonological complexity and prosodic structure in assessment of Serbian phonological development

Directory of Open Access Journals (Sweden)

Nevena Buđevac

2010-06-01

Full Text Available In this research we investigate the relevance of phonological parameters in acquisition of Serbian language. Implementation of British Test of Phonological Screeing (TOPhS, van der Lely and Harris, 1999 has revealed that phonological complexity (syllabic and metrical structure influences accuracy in non-word repetition task and could be used in assessment of phonological development of typically developing children, as well as of children with Grammatical Specific Language Impairment (G-SLI (van der Lely and Harris, 1999; Gallon, Harris & van der Lely, 2007. Having in mind phonological properties of Serbian language (Zec, 2000, 2007, we hypothesized that several parameters can be used in assessment of phonological development in Serbian: a. onset (consonants cluster at the beginning of syllable; b. rime (consonant at the end of syllable. c. word of three syllables, and d. placement of stressed syllable in a word. Combination of these parameters gave us a list of 96 pseudo words of different levels of complexity. Participants were 14 adults and 30 children from kindergarten divided into three age groups (3, 4 and 5 years. Task for the participants was to loudly repeat every pseudo-word, and their reproduction was recorded. Transcription of their answers and coding of errors allowed us to analyze impact of different parameters on accuracy of phonological reproduction in children of different ages. The results indicate that the ability for reproduction of Serbian phonological properties develops in early preschool period. The most difficult is cluster of consonants at the beginning of syllable, and consonant at the end of syllable. These two parameters are even more difficult for reproduction in three-syllable words or in words that have more then one parameter marked. Placement of stress in a word is acquired even before 3 years. In other words, the results have shown that investigated features could be good indicators in assessment of early

The East and the West in the polemical context of the Serbian music between the two World Wars

Directory of Open Access Journals (Sweden)

Tomašević Katarina D.

2005-01-01

Full Text Available This article represents a fragment of the author's doctoral dissertation Serbian Music at the Crossroads of the East and the West? On the Dialogue between the Traditional and the Modern in Serbian Music between the Two World Wars (the review of the thesis see on www.newsound.org.yu, issue No 24. The thesis (mentor: prof. Dr Mirjana Veselinović-Hofman was defended at the Faculty of Music, Belgrade, on January 2004. A revised text of the dissertation is forthcoming, in an edition of the Institute of Musicology of the Serbian Academy of Sciences and Arts. The article describes the creative orientation of composers Miloje Milojević, Petar Konjović and Josip Slavenski as the key figures of the epoch, indicates their choices of an Eastern or Western orientation, and explains the antagonism between the poetics of the "Europeans" and the representatives of avant-garde trends. The topicality of the East-West dichotomy in the critical consciousness of the protagonist of this period is marked as one of the main and the most important dilemma of the polemical context of the Serbian art after the World War I. Conducted from standpoints "Pro et Contra Europe", East-West discussion was also the part of the debate of Serbian national art's development strategy in the new, modern epoch of its history.

Motives for food choice among Serbian consumers

OpenAIRE

Gagić Snježana; Jovičić Ana; Tešanović Dragan; Kalenjuk Bojana

2014-01-01

People's motives for food choice depend on a number of very complex economic, social and individual factors. A Food Choice Questionnaire (FCQ), an instrument that measures the importance of factors underlying food choice, was used to reveal the Serbian consumers' food choice motives by survey of 450 respondents of different age groups. A confirmatory factor analysis was conducted on the motive items, using 11 factors. Previous research shows that the nutrition in Serbia is not balanced enough,...

Effects of chronic infusion of a GABAA receptor agonist or antagonist into the vestibular nuclear complex on vestibular compensation in the guinea pig.

Science.gov (United States)

Gliddon, Catherine M; Darlington, Cynthia L; Smith, Paul F

2005-06-01

The aim of this study was to determine the effects of chronic infusion of a GABA(A) receptor agonist/antagonist into the ipsilateral or contralateral vestibular nuclear complex (VNC) on vestibular compensation, the process of behavioral recovery that occurs after unilateral vestibular deafferentation (UVD). This was achieved by a mini-osmotic pump that infused, over 30 h, muscimol or gabazine into the ipsilateral or contralateral VNC. Spontaneous nystagmus (SN), yaw head tilt (YHT), and roll head tilt (RHT) were measured. Infusion of muscimol or gabazine into either the ipsilateral or the contralateral VNC had little effect on SN compensation. In contrast, infusion of muscimol (250, 500, and 750 ng) into the contralateral VNC and gabazine (31.25, 62.5, and 125 ng) into the ipsilateral VNC significantly affected YHT and RHT (p 0.05). Interestingly, the effects of muscimol and gabazine on YHT and RHT were consistent throughout the first 30 h post-UVD. Infusion of muscimol (62.5, 125, and 250 ng) into the ipsilateral VNC and gabazine (125, 375, and 750 ng) into the contralateral VNC had little effect on YHT and RHT or their rate of compensation. These results suggest that the ipsilateral gabazine and contralateral muscimol infusions are modifying the expression of the symptoms without altering the mechanism of compensation. Furthermore, the neurochemical mechanism responsible for vestibular compensation can cope with the both the GABA(A) receptor-mediated and the UVD-induced decrease in resting activity.

Criticism of the narrative works of Gabriel García Márquez in Serbian literary magazines

Directory of Open Access Journals (Sweden)

Vesna Z Dickov

2014-12-01

Full Text Available Since the Serbian translation of the novel One Hundred Years of Solitude appeared in 1973, the narrative works of Gabriel García Márquez have continued to interest Serbian critics. After an initial break with readers’ expectations, criticism of the magical realism and other aspects of the prose of García Márquez soon (from 1975 began to develop in Serbia, and intensified in the later seventies of the last century as well as at the end of the first decade of the 21st century, when a series of essays, reviews, articles and studies were published on the novels, stories, reportages, essays and memoirs of García Márquez, including his journalistic work. Half of the texts written by Serbian critics for literary journals came out in Belgrade, especially in Književna reč (The Literary Word, the most prolific authors being Radomir Ivanović and Branko Anđić. The judgment of Serbian critics, presented in the literary magazines, which was based frequently on the latest advances in narratology, genealogy and comparative literature, has contributed greatly to the shaping of readers’ expectations not only regarding Gabriel García Márquez’s prose but also new Latin American narrative in general.

Deoxynivalenol occurrence in Serbian maize under different weather conditions

Directory of Open Access Journals (Sweden)

Jajić Igor M.

2017-01-01

Full Text Available The aim of this paper was to investigate deoxynivalenol (DON occurrence in maize samples originating from two harvest seasons in Serbia. The key differences between harvest seasons were weather conditions, specifically the humidity. The samples were analyzed using high performance liquid chromatography with DAD detection, after clean-up on SPE columns. In samples from 2014, DON was found in 82 (100.0% samples with the average content of 2.517 mg/kg (ranged from 0.368 to 11.343 mg/kg. Two samples exceeded maximum level permitted by EU regulations. However, analyzing larger number of samples (163 from 2015 harvest season, DON was present in 51 (31.3% samples in significantly lower concentrations (average of 0.662 mg/kg, ranged from 0.106 to 2.628 mg/kg. None of the samples from 2015 exceeded maximum level permitted by EU regulations. The data on DON presence in Serbian maize were in relation to the different weather conditions that prevailed during the two harvest seasons. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 172042

Views of Europe among Serbian political and cultural elite in late 20th and early 21st century

Directory of Open Access Journals (Sweden)

Jakšić Božidar

2006-01-01

Full Text Available On the basis of his own previous research the author examines views of Europe held by the Serbian political and cultural elite in the late 20th and early 21st century. Unable to meet the challenges of the historical moment, this elite has brought Serbia into open conflict with its closest neighbors and exposed its citizens to international sanctions. War-mongering propaganda of the major state-controlled media was developing feelings of xenophobia and frustration among citizens. The collusion between authoritarian government and war profiteers was systematically destroying the lives of Serbian citizens, bringing them to the brink of material impoverishment and spiritual misery. The process of dissolution of the common Yugoslav state is coming to its end in the first decade of this century. Just as it lacked wisdom political will or strength to prevent armed conflicts and crimes, the Serbian elite today is unable to condemn war crimes, to face disastrous consequences of its own policies, and to help Serbian citizens find their way to prosperity.

Serbian translation of French Code of Civil Procedure from 1837: Part two: Legal terminology of the translation

Directory of Open Access Journals (Sweden)

Stanković Uroš N.

2015-01-01

Full Text Available The article deals with legal terms appearing in Serbian translation of French Code of Civil Procedure (Code de procédure civile, 1806 authored by Serbian writer and politician Lazar Zuban (1795-1850. The author made an attempt to determine whether the terms used by Zuban had existed in historical sources previous to the translator's work. If so, it would mean that Zuban was using already existing technical terms. In cases in which he failed to find certain legal term in texts older than Zuban's work, the author tried to establish if the unfound term had been the translator's invention. As to the terms of civil law, Zuban mostly took over words already present in Serbian vocabulary at the time. This fact is easily explainable: family, property, contracts, torts, inheritage are very present in people's everyday life, which brought about terminology of civil law to be relatively developed. On the contrary, terms belonging to the civil procedure were scarce because judiciary and court procedure in the time of Zuban's work were still being on rudimentary level. That is the reason why the translator had to forge his own legal terms. Zuban did not translate German legal terms (the translator used German translation of a Code as protograph mechanically; he was making effort to fathom the meaning of a word in question and find its adequate Serbian equivalent. In some cases that effort was fruitful. Nevertheless, in a long term Zuban's labor was in vain, as none of his forged words survived in Serbian legal terminology.

Allergen labelling in meat, dairy and cereal products from the Serbian market

Science.gov (United States)

Spirić, D.; Nikolić, D.; Ćirić, J.; Janković, S.; Stefanović, S.; Janković, V.; Teodorović, V.

2017-09-01

Allergens in food are a great health risk, because of the ratio of severity of problems compared to small amounts of ingested allergen. Since 2014, Serbian producers and importers of food have been obliged to declare allergens from the list of Codex Alimentarius on the product packaging. Surveillance of different meat, diary, and cereal product took place in 2016, with aim of checking if the Serbian regulatory requirements for labelling of allergens in food are being fulfilled. Out of 68 different meat products, 20 were not labelled for allergens. Thirty-six labels of various dairy products were examined revealing that allergen information was included on 27 of them. Only one of eight examined cereal products did not have allergen labelling.

Culture can make the state: For the centenary of the death of the Serbian scientist and statesman Stojan Novakovic

Directory of Open Access Journals (Sweden)

Vuković Đorđe

2015-01-01

Full Text Available Numerous political, national and cultural issues that are more than a century dealt with the great Serbian statesman and scientist Stojan Novakovic historical destiny again set before generation of contemporary Serbian intellectuals and patriots. In this article we will try to point out the fundamental point of view Novakovic, designed and imbued his elaborate knowledge and experience as prime minister, diplomats, parliamentarians, scientists, publicists. Novakovic highlights the signs by which not only can we fathom the significance of certain historical phenomena and processes that followed the Serbian society, but also to recognize and determine the challenges we will inevitably face and intertwine in the future. Political ideas about building and strengthening state-permanent form, the necessity of a national program, as well as cultural and educational tasks at which he testified, have a lasting, zavjetanu force, as well as the message that the national aspirations of the Serbian people should be reflected and implemented through universal human, universal values. Today's situation in Serbian society witnessed how wise and far-sighted Novakovic warnings to constitutional order and freedoms of people are losing every sense of importance and if you do not come from the universal acceptance of legality, order, permanence and serious work, diligent preservation of all violence and arbitrariness. The aim of a strong rule of law and to prevent that ever happening again arbitrariness of individuals who should be placed on her forehead. Novakovic was particularly interested in how to be 'dismembered Serbian nation' to know each other, closer and unify national culture. He notes that there is no freedom without education, making education and politics must act together.

Undergraduate business students' attitudes towards CSR and competitiveness of Serbian economy

Directory of Open Access Journals (Sweden)

Ćoćkalo Dragan

2015-01-01

Full Text Available This paper presents the findings of the research dealing with the importance of corporate social responsibility (CSR and its connections with competitiveness. The authors deal with competitiveness of enterprises, as well as activities that promote socially responsible business in Serbia. Special attention is given to the review and analysis of research results of Serbian undergraduate business students' attitudes on CSR and competitiveness. In a five-year- period the research included over 3,300 examinees. The population was built on students from universities and business schools located in total 22 cities and municipalities in Serbia. The research was conducted using questionnaire. Among other, the research has shown that a number of examinees were not informed of the CSR. Students experience the Serbian economy as uncompetitive and have identified several factors that are lacking in the development of competitiveness.

The Political Mobilization of Serbian Communists in the First Phase of the "Antibureaucratic Revolution"

Directory of Open Access Journals (Sweden)

Vladimir Ribić

2016-02-01

Full Text Available This paper offers an analysis of concrete actions and legitimations, and also of the elements of the action- and legitimation basis of the Serbian communists’ political moblization conducted during the first phase of the so-called Antibureaucratic Revolution, which began in April 1987 with Slobodan Miloševi R’s speech in Kosovo Polje, and came to an end with the intra-party showdown at the Eighth Session of the Serbian Communist Party’s Central Committee in September of the same year. The paper also provides a reconstruction of the political context in which the mobilization was conducted.

Research of consumers’ attitudes on the organic food consumption in the Serbian enclaves in Kosovo

Directory of Open Access Journals (Sweden)

Maksimović Goran

2017-01-01

Full Text Available The organic production in Serbian enclaves in Kosovo has a great potential based on the extensive production mostly in hilly-mountainous areas with rich and convenient environment for the organic production of medicinal plants, fruits, vegetables, wine, honey etc., but it still keeps developing. The enclave can realise a high income, and thereby also an economic basis for the sustainable development of multifunctional agricultural holdings in Serbian enclaves, by the production and sale of organic products on local markets. In this paper, the authors study the consumers’ attitudes on purchase and consumption of organic food in Serbian enclaves in Kosovo. Empirical research was carried out on a spatial sample of 300 respondents, by a personal communication technique using the questionnaire as an instrument of research method. Areas of research are towns: Northern Kosovska Mitrovica, Leposavic, Zubin Potok and Gracanica. Goal of the research is to discover the preferences, motives, attitudes and interests of consumers for buying the organic products, based on a defined survey to recognise the basic features of supply and the demand of organic agricultural and food products. After analysing the conducted survey, we have discovered that the organic food market in Serbian enclaves in Kosovo has not been sufficiently developed; it is necessary to expand the range of organic agriculture products and a constant supply is required, better marketing, and better information and education of consumers in order to raise supply to a higher level.

Some features of a typical house as perceived by native speakers of English and of Serbian

Directory of Open Access Journals (Sweden)

Dilparić Branislava M.

2015-01-01

Full Text Available The paper reports findings from one of the two differently-designed surveys conducted among groups of both native speakers of English and native speakers of Serbian with a common general objective to obtain a picture of better candidates for a role of the whole (to be analyzed into its constituent elements in the contrastive study on the lexical field a house and its parts in English and Serbian. The specific objective of the survey presented here, however, was to build up the target picture with some of the features of the ideal example of the house category, such as the shape of the house, the key materials its principal structural elements (foundations, walls, a roof are made of, the number of residential units in the house and the type of the household that occupies it, the number of the house levels, the minimum of its interior spatial components and their functions, the types of systemic parts in the house, the status and position of the house relative to surround­ing buildings, etc. Also, taking into consideration that the demographic profiles of the survey participants reflected various cultural backgrounds (which significantly influence the formation of mental images of a typical sample of the category, the survey aimed to compare the similarities and differences between the 'English' and the 'Serbian' typical house, that is the features assigned to a typical house by most of the surveyed representa­tives of Anglo-American and by those of Serbian culture. Judging exclusively by the features observed and the results obtained, the study concludes that the 'English' and the 'Serbian' typical house look very similar in many aspect and that the two different cultures are not as distant as they may seem.

"Social horror": A critical analysis of ideological and poetic function of the motive of victim in the contemporary Serbian film

Directory of Open Access Journals (Sweden)

Kronja Ivana

2016-01-01

Full Text Available This paper analyses achievements of Serbian cinematography after 2000, which narrative strategies and visual aesthetics are focused on the issues of violence and victims in the context of social despair, post-communist transition and ongoing global value crisis. Films made by Mladen Đorđević Life and Death of a Porn Gang (2009, Srđan Spasojević A Serbian Movie (2010, and Marko Novaković Menagerie (2012 integrate these complex characteristics of disintegration of Serbian community and dysfunctional state system into their cinematic poetics. These films present examples of radical film aesthetics, which, through strategies of making things unusual, and the influence of underground, pornography and horror on the realistic drama, speak about permanently traumatised Serbian society. They directly connect collective political state and the domain of personal, family, intimate and sexual, controversially relying on the images and narratives of gender misogyny and the violence it produces and its victims. The paper critically approaches these issues from the gender- feminist perspective.

Nationality non-discrimination in Serbian tax treaty law

OpenAIRE

Kostić Svetislav V.

2014-01-01

This paper deals with the nationality non-discrimination provision in Serbian double taxation treaties. First the author analyses the historical development of the nationality non-discrimination clause found the in the OECD Model Tax Convention and illustrates the dilemmas related to its interpretation, particularly the relevance of residence of taxpayers for comparability purposes and the application of Art. 24.1 of the OECD Model Tax Convention. Subsequently, the author turns his attention ...

[Articles on elderly in Serbian medical journals].

Science.gov (United States)

Despotović, Nebojsa; Milosević, Dragoslav P; Erceg, Predrag; Davidović, Mladen

2009-01-01

Population aging is a feature of all countries in the world. According to statistics, the Republic of Serbia is one of the countries with the majority of the elderly. Taking this into account, are articles on the elderly well represented in domestic medical journals? The aim of the paper was to determine whether there was a sufficient number of articles on the elderly in domestic medical journals. The articles on the elderly were searched using search engines in domestic and foreign medical journals for the last 5 years compared with the number of articles on children in the same publications for the same period. In the Serbian Citation Index, 11 articles on the topic of the elderly, and 487 on children were registered. In Srpski arhivza celokupno lekarstvo, there was registered only one article on the topic of the elderly, and 30 on children. In Vojnosanitetskipregled, 2 articles on the elderly and 13 on children were registered (p articles on the elderly and 759 articles on children; in the JAMA, there were 63 articles on the elderly and 303 articles on children; and in The Lancet, in the last five years, 46 articles on the elderly and 148 articles on children were published. The themes of the elderly were rarely represented in Serbian medical journals.This has reduced the interest of physicians in medical problems of this growing population of patients and further sent them away from making standards in the diagnosis and treatment of the elderly.

Mechanisms of cell death induced by infusion sets leachables in in vitro experimental settings.

Science.gov (United States)

Kozlovskaya, Luba; Stepensky, David

2015-01-30

Leachable materials that are released from infusion sets during their use can induce local and systemic toxic effects. We studied the mechanisms and kinetics of cell death induced by infusion sets leachates in vitro using L-929 and bEnd. 3 cells. Changes in cell morphology and metabolic activity were determined using light microscopy and the MTT test, respectively. Detailed analysis of the mechanisms of cell death was performed using membrane integrity and caspases 3 and 7 activity tests, annexin V-FITC/7-AAD analysis by FACS, and DAPI nuclear staining followed by confocal microscopy. Infusion sets released toxic leachables and induced toxic effects. Latex flashball was the most toxic part of the studied infusion sets, and it potently induced cell oncosis via increased permeability of the cell membrane. Latex-induced decrease in cells metabolic activity and cell death were not accompanied by activation of caspases 3 and 7, changes in nuclear morphology, or substantial annexin V-FITC cell staining. Leachables from the tube part of the infusion sets were less toxic, and induced some biochemical changes without altering the cells morphology. Further studies are needed to reveal the in vivo toxicity of infusion sets and its correlation with the results of in vitro toxicity studies. Copyright © 2014 Elsevier B.V. All rights reserved.

On certain particularities of the Serbian comparative against the background of its situation in other Slavonic languages

Directory of Open Access Journals (Sweden)

Mitrinović Vera

2003-01-01

Full Text Available The paper deals with a special kind of comparative without an overt secundum comparationis, as exemplified by, say, Pale su jače kiše 'stronger rains have fallen', which is freely used in Serbian; it is called, according to the grammatical tradition, absolute comparative. Attention has been drawn, while attempts were made at revealing the crucial features of the absolute comparative, to the fact that it is marked for its "amplified extension" on the scale of gradation; this shows that the comparative in the kind of use now under consideration has not lost its nature of an instrument of comparison. The grammatical structure in question has also been characterized as displaying sui generis semantic indefiniteness: the point is that the lack of the second object of comparison makes the scope of application of a given feature on the gradation scale rather fuzzy. The first part of the paper presents the distribution of the absolute comparative within the Slavonic linguistic area; the presentation is based on the existing grammars of particular Slavonic languages (however, Bulgarian and Macedonian have not been accounted for; the reason was that these languages have been "balcanized". The evidence supplied by grammars allows us to distinguish, within the Slavonic area, two zones: the zone of marginal use of the form in question (Russian or its limited use (Polish, and the zone of its active use, including Slovak, Czech, Sorbian, Slovenian and Serbian. The second part of the work describes the contrast between the situation in Serbian, on the one hand, and the situation in Polish, on the other: the focus is on the distinct divergence of the two languages in terms of textual distribution, frequency of occurrence and stylistic characteristics of the investigated structure. On the basis of the materials of bilateral translations of belletristic works, as well as those of the Serbian journalistic texts (as appearing in Internet, selected types of

Online Corporate Learning in the Serbian Market

Directory of Open Access Journals (Sweden)

Vladimir Zočević

2011-03-01

Full Text Available The purpose of this paper is to examine corporate learning relationsbetween companies, and to investigate the possibility ofconverting of traditional corporate trainings and meetings to modernmeans of communication and education, with particular referenceto the application of online training and the videoconferencesystem in the process. In addition, the objective of this paperis to examine how well informed companies are about the technologyand its introduction into everyday business practice. Theresearch underlines the results of the analyses concerning thepractical aspect of videoconferences both in Serbian companiesand in foreign ones operating through branches in Serbia.

Infusion cisternography

International Nuclear Information System (INIS)

Magnaes, B.; Rootwelt, K.; Sjaastad, O.

1976-01-01

A source of error in cerebrospinal fluid (CSF) infusion tests is leakage at the dural puncture site. The addition of a bolus of radionuclide to the infusion fluid was helpful in detecting the existence of leakage as shown by increased infusion pressure in six of eight patients studied with and without scintigraphic evidence of leakage. Comparison of CSF dynamics in 26 patients studied by infusion cisternography and conventional cisternography showed similar patterns, suggesting no alteration of CSF dynamics by the artificial CSF infusion. Combining the two tests, therefore, resulted in simple identification of the leakage and saved the patient time and discomfort

Historical tradition in Serbian genre literature

Directory of Open Access Journals (Sweden)

Đorđević Ivan

2008-01-01

Full Text Available This paper discusses two Serbian science-fiction stories with a special emphasis on the motives in their narrative structure; the motive analysis is focused on those motives that represent a transposition of 'historical tradition' elements. The key words connecting images appearing in this context are: fear of losing (national identity and a strategy of resistance towards those, who presumably, want to 'take over' the identity. In this sense, a return to 'the historical tradition', in the analyzed texts, aims to reassess certain past models indicating at the same time those that have successfully served and endured as historical models in this discourse.

The Old Serbian Alexander Romance and the Greek Phyllada

Directory of Open Access Journals (Sweden)

Krzysztof Usakiewicz

2014-12-01

Full Text Available The paper includes a short introduction and four excerpts from the Old Serbian Alexander Romance translated into Polish by Maciej Falski.   Tekst zawiera krótką prezentację zagadnienia filiacji Opowieści o Aleksandrze w bałkańskiej przestrzeni kulturowej oraz przekład fragmentów tzw. Serbskiej Aleksandreidy na język polski.

Attitudes of Serbian adults towards e-cigarette use

OpenAIRE

Biljana Kilibarda; Srmena Krstev; Nadezda Nikolic; Nevena Sovic; Nada Kosic Bibic

2017-01-01

Introduction To analyze the attitudes of Serbian adults related to e-cigarettes and provide a basis for the development of targeted interventions. Material and Methods Data were obtained through a survey among the adult population of Serbia conducted via face to face interviewing on a nationally representative sample of 1041 citizens of Serbia 18+ years old. Results Smoking prevalence was calculated at 39.2% (40% male, 39% female). Prevalence of ever use e-cigarettes was 11% ...

BREAD-MAKING QUALITY OF SLOVAK AND SERBIAN WHEAT VARIETIES

Directory of Open Access Journals (Sweden)

Tatiana Bojňanská

2014-02-01

Full Text Available The basic prerequisite for the production of bakery products of a good quality is the knowledge of the quality parameters of raw materials introduced in the production process and the ability to use their potential. The bread making properties of 17 pure European wheat cultivars were analysed. Baking experiments were carried out according to the methodology of the research workplace; 1000 g of flour was processed with the addition of salt, sugar and yeast. Fermentation for 35 minutes at 30 ° C was followed by the baking with steaming (at 240 ° C and then 220 ° C. During an experimental baking test the selected parameters: loaf volume (cm3, specific loaf volume (cm3.100g-1 loaf, volume efficiency (cm3.100g-1 flour, cambering (loaf height/width ratio, bread yield (%, bread yield baking loss (% in bread were evaluated. Loaf volume has been considered as the most important criterion for the bread-making quality. In the analysed samples (11 varieties of Slovak origin and 6 varieties of Serbian origin, the value of this parameter ranged from 3575 cm3 to 5575 cm3 with higher values occurred in Slovak varieties (average 4 640.91 cm3 compared to the Serbian varieties (average 4 363.33 cm3. Based on the complex evaluation of wheat varieties of the Slovak and Serbian origin assessing the selected quality parameters of the baking experiment it can be concluded that in terms of baking quality the three Slovak varieties IS Ezopus, Bonavita and Jarissa were the best. Therefore, they are recommended for cultivation and their subsequent use in the baking industry, in particular for the production of bread According to a baking quality the evaluated varieties can be sorted from best to worst in the following order: IS Ezopus (SK > Bonavita (SK > Jarissa (SK > IS Questor > Etida (SRB > Venistar (SK > Renesansa (SRB > IS Conditor (SK > IS Corvinus (SK > Zvezdana (SRB > Simonida (SRB > Viglanka (SK > IS Agape (SK > NS 40S (SRB > Panonnija (SRB > IS Escoria (SK

The work of the couple Brailowsky in the mirror of Serbian critiques

Directory of Open Access Journals (Sweden)

Mosusova Nadežda

2003-01-01

Full Text Available Leonid (1867-1937 and Rimma (1877-1959 Brailowsky brought to Belgrade National theatre (together with other Russian emigrated stage and costume designers the spirit of the World of Art (Mir Iskusstva, making décor and costumes for 18 performances during the period of 1921-1924. Les romanesques by Edmond Rostand, Le malade imaginaire by Molière, Shakespeare's Richard III, Merchant of Venice and King Lear and two Serbian dramas, Offenbach's Hoffmann's Tales, Faust by Gounod, Smetana's Bartered Bride, Bizet's Carmen Onegin and Queen of Spades by Tchaikovsky, Massenet's Manon, The Tsar's Bride by Rimsky-Korsakov, The Wedding of Miloš by Petar Konjović, the Serbian opera composer, two ballets, Sheherazade and Nutcracker. The artists, husband and wife, were praised for their modernization of the Belgrade scene, for their vivid realization of sets and costumes, for their novelties, especially in Serbian historical dramas by Branislav Nušić and Milutin Bojić, and Shakespeare as well. In operas and ballets they were also respected in some extent, but the pictorial, sometimes independent value of their scenic work, although inspired by music, arouse opposing questions among the musical critics, who could not accept their too bright colors which once conquered Paris in the scenic interpretation of Leon Bakst or Nikolai Roerich. To avoid resistance of Belgrade critics the couple decided to leave Yugoslav capital for Italy where they continued successfully their artistic career.

Writers and chanters in the nineteenth century as keepers of the tradition of Serbian church music

Directory of Open Access Journals (Sweden)

Marjanović Nataša

2014-01-01

Full Text Available In this paper, parts of the memoir literary works from the second half of the nineteenth century are presented as important sources for the research of Serbian traditional church chant. The testimonies on church music from diaries, memoirs and autobiographical notes by famous Serbian writers, statesmen and politicians, namely Jovan Subotić, Jakov Ignjatović, Milan Savić, Milica Stojadinović Srpkinja, Todor Stefanović Vilovski, Vladimir Jovanović and Kosta Hristić, were analyzed. Those writings bring to light a time when church chant was appreciated as an important part of the spiritual, folk heritage and had an important role in everyday culture of Serbian people both in the Habsburg Monarchy and in the Principality and Kingdom of Serbia. The authors wrote about musical skills of chanters from clerical, church circles and about the practice of chanting among school teachers. They also described different kinds of musical performances of church chant among laymen and children. These sources testify to writers’ general and musical education and experiences, to their environment and its relation to the aesthetics of spiritual folk tradition. This paper also analyzes sources in the context of the history and theory of literature, having in mind the authors’ commentary techniques and narrative style. Those issues are discussed in relation to the poetics of romanticism, Biedermeier and realism in Serbian literature. [Projekat Ministarstva nauke Republike Srbije, br. 177004: Identiteti srpske muzike od lokalnih do globalnih okvira: tradicije, promene, izazovi

Infusion Extractor

Science.gov (United States)

Chang-Diaz, Franklin R.

1988-01-01

Apparatus and method of removing desirable constituents from an infusible material by infusion extraction, where a piston operating in a first chamber draws a solvent into the first chamber where it may be heated, and then moves the heated solvent into a second chamber containing the infusible material, and where infusion extraction takes place. The piston then moves the solvent containing the extract through a filter into the first chamber, leaving the extraction residue in the second chamber.

Analysis of cervical cancer cells treated with radiotherapy or arterial infusion chemotherapy

International Nuclear Information System (INIS)

Izutu, Toshihiko; Nishiya, Iwao

1995-01-01

The present study was designed to analyze cervical cancer cells treated with radiotherapy or intraarterial infusion of CDDP using image analysis. Total nuclear extinction (TE), 5 N-exceeding rate (5 NER) and nuclear area (NA) gradually increased following irradiation, in cervical cancer cases. TE and 5 NER increased markedly following radiotherapy in good response cases. TE, 5 NER and NA were not-changed following irradiation in poor response cases. 5 NER, in good prognostic cases was higher than in poor prognostic cases, significantly among cervical cancer cases treated with radiotherapy. 5 NER and NA increased dramatically in good response cases treated with intraarterial infusion of CDDP. (author)

The Role of Serbian Higher Business Education in Overcoming the Challenges of SME Managers

Directory of Open Access Journals (Sweden)

Maja Kočevar

2014-06-01

Full Text Available In this exploratory study, in-depth interviews with Serbian managers of small and medium-sized enterprises (SMEs were conducted to identify their main work-related challenges and the extent to which formal higher business education has helped them to overcome these challenges. Serbian SME managers find the main challenges to be related to HR- and marketing-related issues, followed by country-specific problems, such as dealing with bureaucracy, difficulties in obtaining financial resources, and coping with delayed payments. They see considerable deficits in the current system of higher business education, specifically referring to a lack of practice-oriented teaching methods and insufficient cooperation between the universities and the business sector.

Models of kulture in Nabokov's memoirs and translation memoirs in Serbian and Croatian language

Directory of Open Access Journals (Sweden)

Razdobudko-Čović Larisa I.

2012-01-01

Full Text Available The paper presents an analysis of two Serbian translations of V. Nabokov's memoirs, that is the translation of the novel 'Drugie berega' ('The Other Shores' published in Russian as an authorized translation from the original English version 'Conclusive Evidence', and the translation of Nabokov's authorized translation from Russian to English entitled 'Speak, Memory'. Creolization of three models of culture in translation from the two originals - Russian and English - Is presented. Specific features of the two Serbian translations are analyzed, and a survey of characteristic mistakes caused by some specific characteristics of the source language is given. Also, Nabokov's very original approach to translation which is quite interpretative is highlighted.

Modelling the benchmark spot curve for the Serbian

Directory of Open Access Journals (Sweden)

Drenovak Mikica

2010-01-01

Full Text Available The objective of this paper is to estimate Serbian benchmark spot curves using the Svensson parametric model. The main challenges that we tackle are: sparse data, different currency denominations of short and longer term maturities, and infrequent transactions in the short-term market segment vs daily traded medium and long-term market segment. We find that the model is flexible enough to account for most of the data variability. The model parameters are interpreted in economic terms.

Model of experimental clonal seed orchard for the production of Serbian spruce šPicea omorika /Panc./Purkyne intraspecific hybrids

Directory of Open Access Journals (Sweden)

Šijačić-Nikolić Mirjana

2002-01-01

Full Text Available The presented model for the establishment of an experimental clonal seed orchard of Serbian spruce was designed based on the results of the analysis and assessment of the genetic potential of Serbian spruce seedling seed orchard at Godovik. Based on the results of the analyses, eight superior half-sib lines of Serbian spruce were selected, of which 24 genotypes were selected. Their hybridisation, by the model of incomplete diallel cross resulted in 21 combinations at the level of half-sib lines, i.e. 48 combinations at the level of parent genotypes. The applied study methods identified the potentially valuable genotypes-cone producers i.e. pollinators, which will be fixed by cloning in the seed orchard of the second generation for the production of the promising hybrids.

Monitoring process hygiene in Serbian retail establishments

Science.gov (United States)

Vesković Moračanin, S.; Baltić, T.; Milojević, L.

2017-09-01

The present study was conducted to estimate the effectiveness of sanitary procedures on food contact surfaces and food handlers’ hands in Serbian retail establishments. For that purpose, a total of 970 samples from food contact surfaces and 525 samples from workers’ hands were microbiologically analyzed. Results of total aerobic plate count and total Enterobacteriaceae count showed that the implemented washing and disinfection procedures, as a part of HACCP plans, were not effective enough in most retail facilities. Constant and intensive education of employees on proper implementation of sanitation procedures are needed in order to ensure food safety in the retail market.

Serbian oil sector: A new energy policy regulatory framework and development strategies

International Nuclear Information System (INIS)

Karovic Maricic, Vesna; Danilovic, Dusan; Lekovic, Branko

2012-01-01

Serbia has established a great part of new legislative and institutional framework as a basis for all energy sub-sectors' development in compliance with EU energy acquis. Main objectives of Serbian energy policy outlined in the new Energy Law are focused to increasing the energy supply security, energy efficiency, competitiveness of the energy market, use of renewable energy sources and environmental protection. Further steps of Serbia toward full EU membership concerning the new energy policy regulatory framework involve implementing and enforcing legislation. Besides considering the issue of Serbian energy policy and degree of its framework's alignment with the EU acquis, this paper provides an overview of new development strategies in the oil sector. The aim of Gazprom neft, a majority owner of the Petroleum industry of Serbia, is to increase crude oil production to 3 million tonnes, refining and sales volume of petroleum products to 5 million tonnes by 2020. Strategic development projects in crude oil and petroleum products transportation are: petroleum product pipeline construction in Serbia and Pan-European oil pipeline. The basic prerequisites for oil supply security, regarding the future high dependency of Serbian economy on imported oil, are establishment of the emergency oil stocks and diversification of supply sources. - Highlight: ► New energy policy regulatory framework significantly complied with EU acquis. ► Full EU membership requires implementing and enforcing new energy legislation. ► NIS-Gazpromneft has defined ambitious oil sector's development programmes to 2020. ► Supply security requires mandatory oil stocks and supply source diversification.

Intersectoral partnerships constitution, framework for Serbian tourism competitiveness growth

Directory of Open Access Journals (Sweden)

Jegdić Vaso

2010-01-01

Full Text Available Intersectoral partnership is a means of strategic management that incorporates economical, social and environmental developmental aims. The Serbian tourist industry is characterized by numerous small and average-sized enterprises with limited resources for research, development, marketing and other investments. That requires addressing other subjects (stakeholders. By establishing partnership networks and clusters, stakeholders acquire necessary means and get opportunities for the development and improvement of competition of tourist products and destinations.

Universal Dependencies for Serbian in Comparison with Croatian and Other Slavic Languages

DEFF Research Database (Denmark)

Starovic, Mirjana; Samardzic, Tanja; Agic, Zeljko

2017-01-01

The paper documents the procedure of building a new Universal Dependencies (UDv2) treebank for Serbian starting from an existing Croatian UDv1 treebank and taking into account the other Slavic UD annotation guidelines. We describe the automatic and manual annotation procedures, discuss the annota...

NOx and SO2 emission factors for Serbian lignite Kolubara

Directory of Open Access Journals (Sweden)

Jovanović Vladimir V.

2012-01-01

Full Text Available Emission factors are widely accepted tool for estimation of various pollutants emissions in USA and EU. Validity of emission factors is strongly related to experimental data on which they are based. This paper is a result of an effort to establish reliable NOx and SO2 emission factors for Serbian coals. The results of NOx and SO2 emissions estimations based on USA and EU emission factors from thermal power plants Nikola Tesla Obrenovac A and B utilizing the Serbian lignite Kolubara are compared with experimental data obtained during almost one decade (2000-2008 of emissions measurements. Experimental data are provided from regular annual emissions measurement along with operational parameters of the boiler and coal (lignite Kolubara ultimate and proximate analysis. Significant deviations of estimated from experimental data were observed for NOx, while the results for SO2 were satisfactory. Afterwards, the estimated and experimental data were plotted and linear regression between them established. Single parameter optimization was performed targeting the ideal slope of the regression line. Results of this optimization provided original NOx and SO2 emission factors for Kolubara lignite.

What, how, and why in Serbian music after the Second World War, in the light of ideological-political upheavals

Directory of Open Access Journals (Sweden)

Veselinović-Hofman Mirjana

2017-01-01

Full Text Available The subject of this paper concerns the consideration of the social and artistic position of Serbian music within the framework of socialist cultural policies and the post-socialist culture of Serbia in transition. That position will be examined from the perspective of some vital creative issues in respect of which aesthetic, poetical and stylistic streams have often been formed or modified, and weighed against each other. This involves the problems of what and how, which ultimately lie at the root of every musical trend and more generally in art, coupled with the problem of why as a certain point of ‘rotation’ at which both the what and the how are met and modified. [Project of the Serbian Ministry of Education, Science and Technological Development: Identities of Serbian Music in the World Cultural Context

Measuring positive and negative affect and physiological hyperarousal among Serbian youth.

Science.gov (United States)

Stevanovic, Dejan; Laurent, Jeff; Lakic, Aneta

2013-01-01

This study extended previous cross-cultural work regarding the tripartite model of anxiety and depression by developing Serbian translations of the Positive and Negative Affect Scale for Children (PANAS-C), the Physiological Hyperarousal Scale for Children (PH-C), and the Affect and Arousal Scale (AFARS). Characteristics of the scales were examined using 449 students (M age = 12.61 years). Applying item retention criteria established in other studies, PH-C, PANAS-C, and AFARS translations with psychometric properties similar to English-language versions were identified. Preliminary validation of the scales was conducted using a subset of 194 students (M age = 12.37 years) who also completed measures of anxiety and depression. Estimates of reliability, patterns of correlations among scales, and age and gender differences were consistent with previous studies with English-speaking samples. Findings regarding scale validity were mixed, although consistent with existing literature. Serbian translations of the PH-C, PANAS-C, and AFARS mirror the original English-language scales in terms of both strengths and weaknesses.

Ludwik Fleck’s concepts slicing through the Gordian Knot of Serbian Archaeology

Directory of Open Access Journals (Sweden)

Monika Milosavljević

2016-12-01

Full Text Available This article delves into the work of a researcher group based around the Center for Theoretical Archaeology in Belgrade (2007 – present and the path they have taken to establish a foundation for further archaeological development within Serbia. This process illuminates the conceptual tools Fleck originally formulated - thought collectives, thought style, proto-ideas – which have played a significant role in the deconstruction of the concept of scientific fact and in the historicization / socialization of the theory of knowledge. For the Serbian archaeological community, one of the most fiendish aspects has been the ever present correlation between the field and the construction of a national identity - an especially painful theme for the postwar Balkans whose borders are still imprecisely defined. Hence, this work pays special attention to long held beliefs of ethnicity, ethnogenesis and continuity, emanating from outdated racial anthropology, but unfortunately still held as fact in Serbian archaeology.

Serbian insurance market: Select issues

Directory of Open Access Journals (Sweden)

Obadović Mirjana M.

2010-01-01

Full Text Available Every day insurance companies face a number of risks arising from the insurance industry itself, as well as risks arising from insurance company operations. In this constant fight against risks insurance companies use different models and methods that help them better understand, have a more comprehensive view of, and develop greater tolerance towards risks, in order to reduce their exposure to these risks. The model presented in this paper has been developed for implementation in insurance risk management directly related to insurance company risk, i.e. it is a model that can reliably determine the manner and intensity with which deviations in the initial insurance risk assessment affect insurance company operations, in the form of changes in operational risks and consequently in insurance companies’ business strategies. Additionally we present the implementation of the model in the Serbian market for the period 2005-2010.

Life and work of Pavle Šeroglić (1800-1857: Part one: Draft biography of the first reviewer of Serbian Civil Code

Directory of Open Access Journals (Sweden)

Drakić Gordana M.

2016-01-01

Full Text Available The article sheds light on life and work of the first reviwer of Serbian Civil Code Pavle Šeroglić. The paper is divided in two parts, first of which is concerned with Šeroglić's private and public life, as the second provides data on his career as a barrister. Šeroglić was born on July 25th, 1800 in Sremski Karlovci. He finished elementary school and renown Sremski Karlovci Grammar School in his place of birth. Having completed his middle school education, Šeroglić studied philosophy in Szeged and law in Sárospatak, Pest and Vienna. As Šeroglić was a bachelor who had no children, he had been very supportive towards his nephew Grigorije (latter German Anđelić, who later became the patriarch of Serbian Orthodox Church. Šeroglić was the benefactor of Sremski Karlovci Grammar School, to which he donated money and books. Besides then patriarch of Serbian Orthodox Church Josif Rajačić, Šeroglić is the most creditable figure for building an orthodox garrison chapel in Petrovaradin. In the beginning of his work as a barrister, Šeroglić was often accused of some acts beyond the limit of morality, such as giving legal advice for both parties in civil lawsuits. Notwithstanding such behaviour, in the years to come Šeroglić represented some very prominent individuals and institutions, such as former Serbian prince Miloš Obrenović, Austrian military treasury, inheritance mass of deceased Serbian metropolitan Stefan Stanković, catholic church Saint Mary of Snow (Tekije in Sremski Karlovci, and famous Serbian poet Jovan Jovanović Zmaj's father in law Pavle Ličanin. Šeroglić died on February 12th, 1857. He testated all his property to Sremski Karlovci Grammar School. During his lifetime Šeroglić showed goodness and generosity towards his cousins, Sremski Karlovci Grammar School and Serbian Orthodox Church. As a barrister, however, he did not always distinguish himself in morality, but judging by the names of his clients, he

Use of traditional motives in Serbian science-fiction literature

Directory of Open Access Journals (Sweden)

Đorđević Ivan

2006-01-01

Full Text Available Subject of this paper is consideration of use of traditional motives in Serbian science-fiction literature in relation with socio-cultural milieu of Serbia from late 80s until now. The author tries to point out ways of usage and construction of some traditional and mythological patterns in certain literature works. This genre of literary production is perceived as a popular culture phenomenon - with this premise, the paper intents to analyze communication process between text and audiences.

The Economic Viability of Ethnicity: Economic Behavior as an Expression of Ethnic Identity among Serbian Immigrants in the USA

Directory of Open Access Journals (Sweden)

Saša Nedeljković

2016-03-01

Full Text Available The economic aspect of ethnicity represents a wide topic of research which still hasn’t been extensively studied in Serbian ethnology and anthropology. It encompasses numerous kinds of relationships between people who belong to the same ethnic group, as well as all kinds of economic discrimination or economic favorizing based on ethnic identity. In this paper I shall attempt to highlight some of the basic characteristics of this issue, and to point out the interconnectedness of economic behavior and ethnic identity, based on one case study. I shall also demonstrate some of the specifics of the socio-economic system within which the studied topic was considered (USA, as well as the complex and ambiguous influence that this system has had on ethnic identity through certain economic actions. The paper focuses on the economic aspect of ethnicity of the Serbian Diaspora in the US, and certain specific issues are considered through the example of the economic behavior of one Serbian immigrant from Romania.

The prevalence of PAI-1 4G/5G gene variant in Serbian population

Directory of Open Access Journals (Sweden)

Đorđević Valentina

2013-01-01

Full Text Available Introduction: Plasminogen activator inhibitor 1 (PAI-1 has a major role in inhibition of firinolysis and normal haemostasis. The presence of the PAI-1 4G/4G genotype leads to increased expression of PAI-1. High blood level of PAI-1 is associated with many diseases such as thrombosis, cerebral insult, myocardial infarction, pregnancy loss, preeclampsia, insulin resistance, type 2 diabetes, breast cancer and asthma. In this study, the prevalence of PAI-1 4G/5G gene variant was determined in healthy subjects from Serbian population. Methods: The study was carried out in a group of 210 healthy subjects (105 women and 105 men. The presence of PAI-1 4G/5G gene variant was detected by PCR-RFLP analysis. Results: The prevalence of PAI-1 4G/4G genotype was 34.76% and it was increased compared to PAI-1 5G/5G genotype (19.05%. The most frequent was PAI-1 4G/5G genotype (46.19%. Allelic frequency for 4G allele was higher (0.58 compared to 5G allele (0.42. Conclusions: The prevalence of PAI-1 4G/5G gene variant in Serbian population is similar to the neighboring populations. Results of this study represent the first data for Serbian population. This study could be useful for further research where the role of PAI-1 4G/5G gene variant will be assessed in the pathogenesis of many diseases.

ELF in English language teaching: Researching attitudes of Serbian academic community

Directory of Open Access Journals (Sweden)

Ošmjanski Vera B.

2016-01-01

Full Text Available The aim of the empirical part of the research was to explore the attitude of the Serbian academic community towards the English language used as lingua franca (ELF, i.e. neutral variety of the English language. The results might be a starting point in considering whether to include ELF in the language policy and, consequently, into English curricula in Serbia. The research included members of Serbian academic community, students of different departments, and English language teachers in the state owned and privately owned universities in Belgrade, Novi Sad and Nis. After examining their attitudes towards key postulates of ELF the conclusions are that it is necessary to start discussions about the concepts of the variety and to reassess current deeply rooted ideas about the English language from the perspective of modern linguistic trends. The need for a more liberal approach to the variety is not generated only in the needs of the market, i.e. those people to whom English is a practical means of international communication, but also the need to adjust ELT (English Language Teaching to modern linguistic tendencies and the European Council recommendations.

The impact of ethnocentrism on Serbian consumers

Directory of Open Access Journals (Sweden)

Veljković Saša

2009-01-01

Full Text Available The purpose of this paper is to examine the impact of consumer ethnocentrism on the intention to buy local products by Serbian consumers. Modern business trends and market changes are followed by new trends in consumer behaviour. Many changes in all segments of economy and society occurred in last few years in Republic of Serbia. Changes were especially influenced by: strong foreign competition, transition, change in values, economy and society liberalization, local culture, and as well by globalization and all other kinds of socio­economic and psychological factors. The globalization of markets presents considerable challenges and opportunities for domestic and international marketers. All these have been influencing on people differentiation concerning ethnocentrism.

The question of autonomy of Bosnia and Herzegovina as Serbian self-defence

Directory of Open Access Journals (Sweden)

Mikić Đorđe

2012-01-01

Full Text Available This work discusses the historical struggle of Serbian people in Bosnia and Herzegovina for the autonomous freedom, through numerous rebellions and uprisings in the 19th century, such as rebellions and uprisings of Serbs in Šumadija. After its success in Serbia under the rule of Miloš Obrenović, Serbs' struggle for the autonomous freedom in Bosnia and Herzegovina in the last period of the Ottoman and later Austro-Hungarian authority was a 'categorical imperative of Serbian self defence'. Resistance to foreign occupiers in Bosnia and Herzegovina was repeated after the disintegration of Yugoslavia in 1991, with the struggle for the autonomous freedom in the Republic of Srpska, for its achievements, challenges and perspectives. On both of these occasions, Serbian people remained and fought for their freedom and unity in the community with other nations. On both of these occasions, destiny and outcome of this successful struggle with opponents were earlier in hands of great powers and later in hands of powerful states. Their earlier and later attitudes towards Serbs were different. Compared to Bulgarians and Bulgaria, or Cretans and Crete, after whose uprisings the great powers awarded them the autonomy, they only promised the same to Serbs while some of them opposed it and corrupted, up until the end of the First World War. It was similar with the struggle of Serbs in Bosnia and Herzegovina for freedom in the achieved Republic of Srpska, up until the United States of America took Bosnia and Herzegovina in its own hands. The States, in cooperation with the Contact Group members, ended the civil war in Bosnia and Herzegovina at the meeting in Dayton in the USA in 1995, while at the same time legitimizing the Republic of Srpska within the two-entity Bosnia and Herzegovina.

Psychometric properties of the Serbian version of the Empathy Quotient (S-EQ

Directory of Open Access Journals (Sweden)

Dimitrijević Aleksandar

2012-01-01

Full Text Available In the present study we examined psychometric properties of the Serbian translation of the Empathy Quotient scale (S-EQ. The translated version of the EQ was applied on a sample of 694 high-school students. A sub-sample consisting of 375 high-school students also completed the Interpersonal Reactivity Index (IRI, another widely used empathy measure. The following statistical analyses were applied: internal consistency analysis, explanatory (EFA and confirmatory (CFA factor analyses, and factor congruence analysis. Correlation with IRI and gender differences were calculated to demonstrate validity of the instrument. Results show that the Serbian 40-item version of EQ has lower reliability (Cronbach’s alpha = .782 than the original. The originally proposed one factor structure of the instrument was not confirmed. The short version with 28 items showed better reliablity (alpha= .807. The three-factor solution (cognitive empathy, emotional reactivity, and social skills showed good cross-sample stability (Tucker congruence coefficient over .8 but the results of CFA confirmed the solution proposed in the reviewed literature only partially. The mean scores are similar to those obtained in the other studies, and, as expected, women have significantly higher scores than men. Correlations with all subscales of IRI are statistically significant for the first two subscales of EQ, but not for the „social skills.” We concluded that the Serbian version of the „Empathy Quotient” is a useful research tool which can contribute to cross-cultural studies of empathy, although its psychometric characteristics are not as good as those obtained in the original study. We also suggest that a 28-item should be used preferably to the original 40-item version. [Projekat Ministarstva nauke Republike Srbije, br. 179018: Identification, measurement and development of cognitive and emotional competences important for a society oriented to European integrations

Towards 3D Cadastre in Serbia: Development of Serbian Cadastral Domain Model

Directory of Open Access Journals (Sweden)

Aleksandra Radulović

2017-10-01

Full Text Available This paper proposes a Serbian cadastral domain model as the country profile for the real estate cadastre, based on the Land Administration Domain Model (LADM, defined within ISO 19152. National laws and other legal acts were analyzed and the incorrect applications of the law are outlined. The national “Strategy of measures and activities for increasing the quality of services in the field of geospatial data and registration of real property rights in the official state records”, which was adopted in 2017, cites the shortcomings of the existing cadastral information system. The proposed profile can solve several problems with the system, such as the lack of interoperability, mismatch of graphic and alphanumeric data, and lack of an integrated cadastral information system. Based on the existing data, the basic concepts of the Serbian cadastre were extracted and the applicability of LADM was tested on an obtained conceptual model. Upon obtaining positive results, a complete country profile was developed according to valid national laws and rulebooks. A table of mappings of LADM classes and country profile classes is presented in this paper, together with an analysis of the conformance level. The proposed Serbian country profile is completely conformant at the medium level and on several high-level classes. LADM also provides support for three-dimensional (3D representations and 3D registration of rights, so the creation of a country profile for Serbia is a starting point toward a 3D cadastre. Given the existence of buildings with overlapping rights and restrictions in 3D, considering expanding the spatial profile with 3D geometries is necessary. Possible solutions to these situations were analyzed. Since the two-dimensional (2D cadastre in Serbia is not fully formed, the proposed solution is to use the 2D model for simple right situations, and the 3D model for more complex situations.

The impact of Privatisation – Empiric analysis and results in Serbian industry

Directory of Open Access Journals (Sweden)

Ivan Nikolic

2014-04-01

Full Text Available The privatization concept, applied after the 2000 changes, failed to bring the expected performance to Serbian industry. Privatization partly initiated the enterprises restructuring in some fields of manufacturing industry. It brought fresh capital, new technologies and new managerial know-how. However, the result thereof was far weaker than the initially expected. The reasons for the said, but also the end aims of the given process, are analyzed in detail throughout the following article. The research is based on the processing of data from financial statements, submitted by the companies from the Serbian non-financial corporate sector in the period 2002-2007. Panel analysis disclosed the way in which the results of each of the observed ownership forms have changed over time in different sectors and branches of the industry. On the other hand, we also tested the hypothesis according to which privatization effects on the companies’ performances significantly vary depending on the company size, whereby the effects of capital sales model have been implicitly assessed.

Music in Serbian literary magazine and Yugoslav ideology

Directory of Open Access Journals (Sweden)

Vasić Aleksandar N.

2004-01-01

Full Text Available It is worth noting that the important journal of the history of Serbian literature and music, the Serbian Literary Magazine (1901 - 1914, 1920 1941, became more Yugoslav-oriented within a relatively short period following its inception. From its early beginning to 1906, the Magazine’s musical critics did not actively express its Yugoslav ideology. But from 1907 there was an increase of interest in both the music and the musicians from Croatia and Slovenia. In 1911 the Croatian Opera spent almost two weeks in Belgrade performing; the composer and musicologist, Miloje Milojević began to develop the idea of union with Slavs from the South in a critical analysis he rendered of their performance. Until the end of the first/old series, SLM highlighted a noticeable number of texts about Croatians and Slovenians: critical reviews of Croatian musical books, concerts of Slovenian artists in Belgrade, score editions of Slovenian music performances of instrument soloists from Zagreb in Belgrade - as well as notes about the musical work of Croatian Academy (Yugoslav Academy of Sciences and Arts, Zagreb. Echoes of rare tours of Serbian musicians in South Slavs cultural centers did not go unheard, either. In the older series of the journal, lasting and two-fold relations had already begun to lean towards Yugoslav ideology. From one side, even before World War I, Yugoslav ideology in the Magazine was accepted as a program objective of Serbian political and cultural elite. On the other, the journal does not appear to have negotiated any of its aesthetic criterion when estimating musical events that came from Zagreb and Ljubljana to Belgrade - at least not "in the name of Yugoslav ideology". In later series of SLM, the Yugoslav platform was being represented as official ideological statehood of newly created Kingdoms of Serbs, Croats and Slovenians (1918, i.e., the Kingdom of Yugoslavia (1929. At that time, the Magazine had occasional literary cooperation from

Balkans as a cultural symbol in the Serbian music of the first half of the twentieth century

Directory of Open Access Journals (Sweden)

Milanović Biljana

2008-01-01

Full Text Available Focus on the internalization of Western images in the Balkans has special significance in researching Serbian art. The functioning of Balkanism as it overlapped and intersected with Orientalism is indicated in the text by an examination of the cases of Petar Konjović, Miloje Milojević and Josip Slavenski, the three significant composers working in Serbia during the first half of the twentieth century. Their modernistic projects present different metaphors of the Balkans. Nevertheless each of them is marked by desire to change the Balkan image into a 'positive' one and thus stands as a special voice for Serbian and regional placing in European competition for musical spaces.

Contextualization of early modernism in Serbian music: Case studies of two works from 1912

Directory of Open Access Journals (Sweden)

Milanović Biljana

2006-01-01

Full Text Available This study deals with the first Serbian oratorio, Vaskrsenje (Resurrection by Stevan Hristić, and the first Serbian musical drama, Divina Tragoedia by Milenko Paunović. These works are based on two different interpretations of the same theme (the Resurrection of Jesus Christ. They were composed almost at the same time (1912, but separately, with no inter-textual relations. They represent the first steps of Modernism in Serbian music. Hristić’s work follows the French and Italian heritage whereas Paunović’s is connected with the German, post-Wagnerian tradition. In this text we highlight the different intensities of modernity realized by the composers, by comparing numerous aspects of the theme, genre and style with new types of expressiveness and procedures in the treatment of all musical resources. The parallel investigation of the oratorio and musical drama shows the closeness of these two young composers in their musical attempts, but also emphasizes some factors that were decisive for the public presentation of their works. Hristić predicted that the genre of oratorio had better chances of placement than, for example, a symphonic or musical-dramatic composition. Actually, a choir had strong links with tradition and it presented a significant means of potential communication, as well as penetrating novelties into other parts of the oratorio. Due to his readiness to make an effort and to compromise, the composer succeeded in performing his work. On the other hand, Paunović did not anticipate problems in the national cultural system of his time. Numerous aspects of his work, which prevented performance, confirm this. The chosen genre of German musical drama was a very speculative investment in the local musical context. Furthermore, the score was inappropriate for the real reproductive potential of Serbian performers. In addition, an avant-garde gesture was marked by the blasphemous treatment of the New-Testament theme in the dramatic

Clinical research involving minors in international and serbian regulations.

Science.gov (United States)

Planojević, Nina; Zivojinović, Dragica

2013-07-01

Participation in clinical trials can be useful for the health of a person, in who it is conducted, but it does not have to be - it can even be harmful. Therefore, primary motive to accept such risk is humanity and human wish to contribute to the progress of medicine; this is expressed by personal consent. The consent, however, can be an expression of personal humanity, and for this, it is not logical that someone can give consent on behalf of someone else, as it is done by a legally authorized representative on behalf of a minor. Therefore, authors raise 3 questions: What are the reasons to consider representative's consent acceptable? How should a model of regulations look like in order to provide the most complete possible protection to a minor? Is actual regulation of minors' position within international and Serbian law, analyzed here by authors for their specific solutions, acceptable? Representative's consent is acceptable only for therapeutic research, because these can bring benefits to everyone's health, including a minor in which those are conducted - this is an acceptable (secondary) motive of participation in the research. Expression of humanity on other's behalf, typical for non-therapeutic research, is not acceptable; this makes ban of minors' participation in non-therapeutic research more appropriate regulation model. International regulations are not in accordance to results presented in the paper for allowing participation of minors both in therapeutic and non-therapeutic research. Serbian regulation is closer to the most acceptable regulation model.

Serbian Astronomers in Science Citation Index in the XX Century

Science.gov (United States)

Dimitrijevic, Milan S.

The book is written paralelly in Serbian and English. The presence of works of Serbian astronomers and works in astronomical journals published by other Serbian scientists, in Science Citation Index within the period from 1945 up to the end of 2000, has been analyzed. Also is presented the list of 38 papers which had some influence on the development of astronomy in the twentieth century. A review of the development of astronomy in Serbia in the last century is given as well. Particular attention is payed to the Astronomical Observatory, the principal astronomical institution in Serbia, where it is one of the oldest scientific organizations and the only autonomous astronomical institute. Its past development forms an important part of the history of science and culture in these regions. In the book is also considered and the history of the university teaching of astronomy in Serbia after the second world war. First of all the development of the Chair of Astronomy at the Faculty of Mathematics in Belgrade, but also the teaching of astronomy at University in Novi Sad, Ni and Kragujevac is discussed. In addition to professional Astronomy, well developed in Serbia is also the amateur Astronomy. In the review is first of all included the largest and the oldest organization of amateur-astronomers in Serbia, founded in 1934. Besides, here are the Astronomical Society "Novi Sad", ADNOS and Research Station "Petnica". In Valjevo, within the framework of the Society of researchers "Vladimir Mandic - Manda", there is active also the Astronomical Group. In Kragujevac, on the roof of the Institute of Physics of the Faculty of Sciences, there is the "Belerofont" Observatory. In Ni, at the close of the sixties and the start of the seventies, there was operating a branch of the Astronomical Society "Rudjer Bokovic", while at the Faculty of Philosophy there existed in the period 1976-1980 the "Astro-Geophysical Society". In the year 1996 there was founded Astronomical Society

Characteristics of Serbian foreign trade of agricultural and food products

Directory of Open Access Journals (Sweden)

Božić Dragica

2016-01-01

Full Text Available Agricultural and food products are a significant segment of the total foreign trade of Serbia, which is characterized by a relatively high import dependency, modest export and constantly present deficit. In such conditions, agrarian sector serves as a stabilizer, and its importance is reflected in the permanently positive balance, increased participation, particularly in total exports, and balancing the trade balance of the country. The aim of the paper is to analyze the basic characteristics of foreign trade of agricultural and food products of Serbia in the period 2005-2015. The tendencies in export, import, and the level of coverage of import by export of agro-food (or agrarian products are analysed. The participation of these products in the total foreign trade of Serbia is also considered, followed by the comparison of this indicator with the neighbouring countries. In the next part of the paper, the structure of Serbian export and import of agricultural and food products (by product groups is analysed. Special attention is given to the territorial orientation of export and import of agrarian products by the most important trade partners. In order to conduct more comprehensive analysis of comparative advantages, or competitiveness of certain groups of agro-food products of Serbia in the exchange with the world, indicator of Revealed Comparative Advantage (RCA is calculated. The analysis of qualitative competitiveness is derived using the indicator - unit value of export and import. The analysis points to the dynamic growth in the value of Serbian export and import of agro-food products, with the constant surplus of trade balance in the observed period. These products are significantly represented in the structure of the total foreign trade of the country, particularly in export (with about 20%. RCA indicators show that Serbia has a comparative advantage in trade of agro-food products to the world in primary products and products of lower

[Jubilees of the Serbian Medical Society. Golden jubilee--a time of renewal and remembrance].

Science.gov (United States)

Vuković, Z

1998-01-01

The Serbian medical association was founded in Belgrade 125 years ago. At that time, Serbia was liberated from the Ottoman domination, and was one of some thirty existing independent states gaining international recognition in 1878. The physicians of the Serbian medical association have shared the fate of their people over the past 125 years. This is best illustrated by the fact that Serbia lost more than 1,000,000 people in World War I and that every third doctor in Serbia lost his life serving his people during the war. This was the highest expression of philanthropy, unsurpassed in the history of mankind. The period of time after the war, was the time of renewal and commemoration. In that time John Maynard Keynes, one of the most outstanding figures in the field of world economics, was on the Peace Conference in Paris, after the World War I, in charge of estimating war damages and the degree of destruction in the Allied countries, but without considering their losses in "human capital"-- the only exception he made for Serbia. In his book "The Economic Consequences of the Peace (published in 1920) he wrote: "The losses of Serbia, although from a human point of view her sufferings were the greatest of all, are not measured pecuniarily by great figures, on account of her low economic development." He quoted some extraordinary figures of the loss of life--"at above 1,000,000, or more than one-third of the population of Old Serbia." In the end he concludes: "Of all the Allies, Serbian sufferings and losses were proportionately the greatest, and after Serbian, the French. In these times, also, according to professor Hichmann (Geographical Statistical Atlas 1920) "it was found, when the nations counted their losses after the war, that Serb casualties amounted to 23% of her population as compared with 3.7% for Great Britain, 8.5% for France and 9.3% for Germany. No small nation can suffer a loss such as Serbia, drawn moreover entirely from its able-bodied manhood

Gender differentiation in the lexicon of the serbian language

Directory of Open Access Journals (Sweden)

Дарія Володимирівна Девлиш

2015-03-01

Full Text Available The article focuses its attention on the concepts "gender", "gender stereotype" and linguistic picture of the world. The lexicon of the Serbian language was researched through the prism of the analysis of synonymic rows which are used to represent character traits of men and women. In the structure of these concepts the following terms were pointed out: external characteristics, physical characteristics, internal characteristics, intellectual characteristics. Within the framework of the microcomponent “internal characteristics” two different negative features of both genders were analyzed: indecisive man, rude man; talkative woman, angry woman. 

A decade of sulphite control in Serbian meat industry and the effect of HACCP.

Science.gov (United States)

Tomasevic, Igor; Dodevska, Margarita; Simić, Milan; Raicevic, Smiljana; Matovic, Violeta; Djekic, Ilija

2018-03-01

In total 7351 meat preparations and fresh processed meat products were analysed from 555 different Serbian meat producers over a 10-year period, 4.5 years before and 5.5 years after mandatory Hazard Analysis and Critical Control Points (HACCP) implementation. From the obtained results, it could be concluded that HACCP has contributed to a better alignment of practices with the legal provisions. The share of non-compliant samples dropped from 18.6% before HACCP to 8.3% after its mandatory implementation. Average sulphite concentrations for all categories of meat preparations and fresh processed meat products decreased by 43%, declining from 33.6 to 19.3 mg kg -1 . Typical misuse and frequent abuse of sulphites was independent of a season. Application of HACCP principles in the Serbian meat industry raised awareness about the misuse of sulphites and contributed to a better control, minimising exposure to sulphites.

The Ethnopsychological Framework of the Croatian and Serbian Nations

Directory of Open Access Journals (Sweden)

Ivo Rendić-Miočević

2000-06-01

Full Text Available The author proceeds from the opinion of E. Gellner that nationalism creates nations, and not vice versa. In South-East Europe homogeneity has been brought about through a traditional model, wherein archetypes and psychological matrices, especially those based on hajduk (bandit myths, proved to be persistent during the 20th century, even in its closing decades. As the historical framework in his analysis, the author uses the concept of Illyricum, and not of the Balkans. The later term was invented only at the beginning of the 20th century and it does not have any historical, cultural or geographic validity. In research on the problem of nationalism and nations in South-East Europe it is possible to apply an ethnopsychological approach, in which Freudian theories can be of great help. In order to understand archetypes that still survive in the area of ancient Illyricum, one must analyse three historical models that were formed during the long centuries in this region: 1 the Croatian-Pannonian feudal model as well as the Mediterranean one in the West, 2 the patriarchal model in the mid-areas, 3 the Serbian “despotic” model in the East. In regard to patriarchal society, the author recognises in its ideology (national songs, myths etc. the Kraljević Marko syndrome (with projections, paranoia and narcism as its symptoms. The author emphasises that the parental super-ego is transferred to children, and so becomes the upholding factor of tradition and values. Mediaeval Serbia, in which Church and State were linked, had a different social development from European society. “Oriental despotism” as a dominant type can be seen in Serbian history from the Nemanjić period, through the Ottoman epoch to the modern Serbian state. During the Ottoman period, a homogeneous national culture prevailed, which was deeply marked by the Dinaric heritage. Stimulating paranoia and projects in the population, the modern state, assisted by the Church, threatened

Safety in Serbian animal source food industry and the impact of hazard analysis and critical control points: A review

Science.gov (United States)

Tomašević, I.; Đekić, I.

2017-09-01

There is a significant lack of HACCP-educated and/or HACCP-highly trained personnel within the Serbian animal source food workforces and veterinary inspectors, and this can present problems, particularly in hazard identification and assessment activities. However, despite obvious difficulties, HACCP benefits to the Serbian dairy industry are widespread and significant. Improving prerequisite programmes on the farms, mainly through infrastructural investments in milk collectors and transportation vehicles on one hand, and increasing hygiene awareness of farmers through training on the other hand has improved the safety of milk. The decline in bacterial numbers on meat contact surfaces, meat handlers’ hands and cooling facilities presents strong evidence of improved process hygiene and justifies the adoption of HACCP in Serbian meat establishments. Apart from the absence of national food poisoning statistics or national foodborne disease databases, the main obstacle to fully recognising the impact of HACCP on the safety of animal source food in Serbia is the lack of research regarding the occurrence of chemical and/or physical hazards interrelated with its production.

Assessing attitudes towards statistics among medical students: psychometric properties of the Serbian version of the Survey of Attitudes Towards Statistics (SATS.

Directory of Open Access Journals (Sweden)

Dejana Stanisavljevic

Full Text Available BACKGROUND: Medical statistics has become important and relevant for future doctors, enabling them to practice evidence based medicine. Recent studies report that students' attitudes towards statistics play an important role in their statistics achievements. The aim of the study was to test the psychometric properties of the Serbian version of the Survey of Attitudes Towards Statistics (SATS in order to acquire a valid instrument to measure attitudes inside the Serbian educational context. METHODS: The validation study was performed on a cohort of 417 medical students who were enrolled in an obligatory introductory statistics course. The SATS adaptation was based on an internationally accepted methodology for translation and cultural adaptation. Psychometric properties of the Serbian version of the SATS were analyzed through the examination of factorial structure and internal consistency. RESULTS: Most medical students held positive attitudes towards statistics. The average total SATS score was above neutral (4.3±0.8, and varied from 1.9 to 6.2. Confirmatory factor analysis validated the six-factor structure of the questionnaire (Affect, Cognitive Competence, Value, Difficulty, Interest and Effort. Values for fit indices TLI (0.940 and CFI (0.961 were above the cut-off of ≥0.90. The RMSEA value of 0.064 (0.051-0.078 was below the suggested value of ≤0.08. Cronbach's alpha of the entire scale was 0.90, indicating scale reliability. In a multivariate regression model, self-rating of ability in mathematics and current grade point average were significantly associated with the total SATS score after adjusting for age and gender. CONCLUSION: Present study provided the evidence for the appropriate metric properties of the Serbian version of SATS. Confirmatory factor analysis validated the six-factor structure of the scale. The SATS might be reliable and a valid instrument for identifying medical students' attitudes towards statistics in the

Assessing attitudes towards statistics among medical students: psychometric properties of the Serbian version of the Survey of Attitudes Towards Statistics (SATS).

Science.gov (United States)

Stanisavljevic, Dejana; Trajkovic, Goran; Marinkovic, Jelena; Bukumiric, Zoran; Cirkovic, Andja; Milic, Natasa

2014-01-01

Medical statistics has become important and relevant for future doctors, enabling them to practice evidence based medicine. Recent studies report that students' attitudes towards statistics play an important role in their statistics achievements. The aim of the study was to test the psychometric properties of the Serbian version of the Survey of Attitudes Towards Statistics (SATS) in order to acquire a valid instrument to measure attitudes inside the Serbian educational context. The validation study was performed on a cohort of 417 medical students who were enrolled in an obligatory introductory statistics course. The SATS adaptation was based on an internationally accepted methodology for translation and cultural adaptation. Psychometric properties of the Serbian version of the SATS were analyzed through the examination of factorial structure and internal consistency. Most medical students held positive attitudes towards statistics. The average total SATS score was above neutral (4.3±0.8), and varied from 1.9 to 6.2. Confirmatory factor analysis validated the six-factor structure of the questionnaire (Affect, Cognitive Competence, Value, Difficulty, Interest and Effort). Values for fit indices TLI (0.940) and CFI (0.961) were above the cut-off of ≥0.90. The RMSEA value of 0.064 (0.051-0.078) was below the suggested value of ≤0.08. Cronbach's alpha of the entire scale was 0.90, indicating scale reliability. In a multivariate regression model, self-rating of ability in mathematics and current grade point average were significantly associated with the total SATS score after adjusting for age and gender. Present study provided the evidence for the appropriate metric properties of the Serbian version of SATS. Confirmatory factor analysis validated the six-factor structure of the scale. The SATS might be reliable and a valid instrument for identifying medical students' attitudes towards statistics in the Serbian educational context.

Radionuclide content in laundry detergents commercially available on the Serbian market and assessment of radiological environmental hazards

Directory of Open Access Journals (Sweden)

Vukanac Ivana S.

2017-01-01

Full Text Available Laundry detergents are chemicals widely used in everyday life, and in numerous industry branches. In order to perceive the radiological aspect of environmental pollution by wastewater, the analysis of laundry detergents available on the Serbian market was undertaken. Laundry detergent samples were measured by means of gamma spectrometry and the results are presented in this paper. Analysis of the obtained activity concentrations showed that laundry detergents in Serbia mostly fulfill the international recommendation and requirements regarding the phosphate content. Besides that, the content of the detected radionuclides in laundry detergent samples indicates the minor radiological risk to the environment via wastewaters. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 171018

Classical elements in the endowments of Serbian XIII century donors

OpenAIRE

Gligorijević-Maksimović Mirjana

2009-01-01

In Byzantine painting, starting from the XIII and particularly during the XIV century, there was a visible return to models from the period of Antiquity. The influences of ancient, ostensibly, Hellenistic heritage were reflected in the shapes, in the content of the compositions, as well as in the drawing, modellation and colours. In the art that came into being in the course of the XIII century, in the endowments of the Serbian donors numerous elements emerged that had existed in ancient art....

Mihailo Lalić and Serbian Ethnology: Ethnography and Mimesis of Patriarchal Society in Montenegrin Highlands

Directory of Open Access Journals (Sweden)

Gordana Gorunović

2017-12-01

Full Text Available My starting point is the yet unexplored supposition that Lalić’s realistic writing about the reality contains also a real ethnological and anthropological reference, first of all comments on the Serbian ethnology of the first half of the 20th century, its traditional paradigm, and strategy of ethnographic writing. My second supposition is that the deeper structure of Lalić’s historical novels is “inscribed” by the genre of ethnography which, together with other text types and stylistic means, contributes to the virtuoso construction of great narratives about the Montenegrin life world in historical perspective. Finally, an analysis of Lalić’s discourse reveals that despite the Marxist inspired criticism of ethnology as part of the Serbian national science, the discipline was an inevitable point of reference in the narrative construction of Montenegrin identity. 

Serbian translation of the 20-item toronto alexithymia scale: Psychometric properties and the new methodological approach in translating scales

Directory of Open Access Journals (Sweden)

Trajanović Nikola N.

2013-01-01

Full Text Available Introduction. Since inception of the alexithymia construct in 1970’s, there has been a continuous effort to improve both its theoretical postulates and the clinical utility through development, standardization and validation of assessment scales. Objective. The aim of this study was to validate the Serbian translation of the 20-item Toronto Alexithymia Scale (TAS-20 and to propose a new method of translation of scales with a property of temporal stability. Methods. The scale was expertly translated by bilingual medical professionals and a linguist, and given to a sample of bilingual participants from the general population who completed both the English and the Serbian version of the scale one week apart. Results. The findings showed that the Serbian version of the TAS-20 had a good internal consistency reliability regarding total scale (α=0.86, and acceptable reliability of the three factors (α=0.71-0.79. Conclusion. The analysis confirmed the validity and consistency of the Serbian translation of the scale, with observed weakness of the factorial structure consistent with studies in other languages. The results also showed that the method of utilizing a self-control bilingual subject is a useful alternative to the back-translation method, particularly in cases of linguistically and structurally sensitive scales, or in cases where a larger sample is not available. This method, dubbed as ‘forth-translation’, could be used to translate psychometric scales measuring properties which have temporal stability over the period of at least several weeks.

Greek loanwords in Serbian vernaculars on the territory of Vojvodina

Directory of Open Access Journals (Sweden)

Vlajić-Popović Jasna

2011-01-01

Full Text Available This paper presents a pilot version of a more comprehensive study on Greek loanwords in Serbian vernaculars which will deal with their identification, distribution, periodisation, and adaptation. The materials excerpted from the presently existing dialectal dictionaries will be compared with the data from three classical sources on the topic: VASMER, POPOVIĆ 1953-1955, and SKOK. In this phase our goal was to find out whether there is any point in proceeding with the study of Greek loanwords in Serbian, after the results that have been reached by the three abovementioned authors. Our choice for the pilot analysis is Rečnik srpskih govora Vojvodine (RSGV because of its size, representativeness and actuality: it is the largest single dictionary (ten volumes comprising over 2,000 pages, it has covered the vastests continual territory (at the same time most distant from the line of contact with Greek, and also beyond the borders of the Balkan linguistic unity, it falls in the number of the most up-to-date ones (published in the period 2001 to 2011. The paper offers not just a linear inventory of Grecisms from RSGV, but a classification of types of divergencies from the standard body of Grecisms. It features primarily novelties - be they represented by new words (ponomarh ‘cleric’, mironisati ‘to pray in the church’, parasnik ‘unruly person’, by new semantics (buklijaš ‘horse ridden by the man who carries buklija’, Grk ‘shopkeeper’, katarka ‘long pole onto which knife for cutting the fishing-net is poised’, kolaba ‘structure for drying meat in the attic’, kondir ‘bucket for cattle; mode of cutting wine’, krevet ‘laundry; chair; the lower layer of sheaves in a stook’, liman ‘underwater source’, mira ‘extract produced by cooking large amounts of fish in little water, used as an additon to fish-stew’, paripa ‘horse farm’, by new formation (krevetnjača ‘a solid piece of wood fencing a straw

On Selected Somatic Phraseologisms in Modern Greek and Serbian (translation Jerneja Kavčič

Directory of Open Access Journals (Sweden)

Predrag Mutavdžić

2011-12-01

Full Text Available Bearing in mind that every element of the linguistic system can be subordinated to the communicative function of language, the authors of this paper seek to provide a contrastive structural and semantic analysis of a particular lexico-semantic group of somatic idioms or phraseologisms (phraseological units containing the names of bodily organs found in the Modern Greek and Serbian languages. This brief analysis, based on a corpus gathered from dictionaries and translated books, is a pioneer work in its field either in Greek or in Serbian literature on phraseology. Since somatic phraseologisms diverge in their structure and semantic features, the authors attempt to find parallels between the two languages in their use of concrete concept forms, with the ultimate aim of explaining and expressing their metaphorical abstract meanings. This entails focusing on a selection of somatic phraseologisms which belong to separate phraseological inventories of the two languages.

Infusion volume control and calculation using metronome and drop counter based intravenous infusion therapy helper.

Science.gov (United States)

Park, Kyungnam; Lee, Jangyoung; Kim, Soo-Young; Kim, Jinwoo; Kim, Insoo; Choi, Seung Pill; Jeong, Sikyung; Hong, Sungyoup

2013-06-01

This study assessed the method of fluid infusion control using an IntraVenous Infusion Controller (IVIC). Four methods of infusion control (dial flow controller, IV set without correction, IV set with correction and IVIC correction) were used to measure the volume of each technique at two infusion rates. The infused fluid volume with a dial flow controller was significantly larger than other methods. The infused fluid volume was significantly smaller with an IV set without correction over time. Regarding the concordance correlation coefficient (CCC) of infused fluid volume in relation to a target volume, IVIC correction was shown to have the highest level of agreement. The flow rate measured in check mode showed a good agreement with the volume of collected fluid after passing through the IV system. Thus, an IVIC could assist in providing an accurate infusion control. © 2013 Wiley Publishing Asia Pty Ltd.

Serbian Written Sources on the Tatars and the Golden Horde (first half of the 14th century

Directory of Open Access Journals (Sweden)

Aleksandar Uzelac

2014-01-01

Full Text Available Serbian narrative and documentary texts, written in the first half of the XIV century, represent valuable source material for the research of Tatar political and military influence in the Balkan lands. Most important among them are Vita of King Stephen Uroš II Milutin (1282–1321, extant in three different editions and Vita of Archbishop Daniel II (1324–1337. The first one offers insight into the relations between the Kingdom of Serbia and the powerful Juchid prince Nogai, while in the latter, the key role of Tatar contingents in internal power struggle between king Milutin and his brother Stephen Dragutin is mentioned. The presence of Tatars in the Battle of Velbazhd (1330, fought between Serbia and the Bulgarian Empire, is also attested in various sources, including the so-called Old Serbian chronicles and the Code of Law of Emperor Stephen Dušan (1349. Another group of sources analyzed in the text are several apocryphal writings of South Slavic literature. Their value lies in the fact that they reflect the image of the Tatars in the eyes of the Balkan Slavs. Last, but not least important testimony of Tatar activities in Serbian lands is preserved in place-names of Tatar origin, recorded in royal charters, issued by Milutin’s son Stephen (1321–1331 and grandson Stephen Dušan (1331–1355.

The Serbian version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR).

Science.gov (United States)

Susic, Gordana; Vojinovic, Jelena; Vijatov-Djuric, Gordana; Stevanovic, Dejan; Lazarevic, Dragana; Djurovic, Nada; Novakovic, Dusica; Consolaro, Alessandro; Bovis, Francesca; Ruperto, Nicolino

2018-04-01

The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient-reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the Serbian language. The reading comprehension of the questionnaire was tested in 10 JIA parents and patients. Each participating centre was asked to collect demographic, clinical data and the JAMAR in 100 consecutive JIA patients or all consecutive patients seen in a 6-month period and to administer the JAMAR to 100 healthy children and their parents. The statistical validation phase explored descriptive statistics and the psychometric issues of the JAMAR: the three Likert assumptions, floor/ceiling effects, internal consistency, Cronbach's alpha, interscale correlations, test-retest reliability, and construct validity (convergent and discriminant validity). A total of 248 JIA patients (5.2% systemic, 44.3% oligoarticular, 23.8% RF-negative polyarthritis, 26.7% other categories) and 100 healthy children were enrolled in three centres. The JAMAR components discriminated healthy subjects from JIA patients. All JAMAR components revealed good psychometric performances. In conclusion, the Serbian version of the JAMAR is a valid tool for the assessment of children with JIA and is suitable for use both in routine clinical practice and clinical research.

Verbal aptitude and the use of grammar information in Serbian language

Directory of Open Access Journals (Sweden)

Lalović Dejan

2006-01-01

Full Text Available The research presented in this paper was an attempt to find differences in the use of grammatical information carried by the function words in Serbian. The aim was to determine the level of word processing at which grammatical information shows its differential effects in groups of subjects who themselves differ in verbal ability. For this purpose, the psycholinguistic tasks applied were grammatically primed reading aloud and grammatically primed grammatical classification with an appropriate control of extra-linguistic factors that may have affected aforementioned tasks. Verbal aptitude was assessed in a psychometric manner, and the subjects were divided into "high verbal" and "low verbal" groups. Taking into account statistical control of extra-linguistic factors, the results indicate that groups of high verbal and low verbal subjects cannot be differentiated based on reading aloud performance. The high verbal subjects, however, were more efficient in grammatical classification than low verbal subjects. The results also indicated that the presence of grammatical information embedded in function words-primes had a stronger effect on word processing in low verbal group. Such pattern of results testify to the advantage of high verbal subjects in lexical and post lexical processing, while no differences were established in the word recognition processes. The implications of these findings were considered in terms of test construction for the assessment of verbal ability in Serbian language. .

Mandatory and Voluntary Disclosures of Serbian Listed Companies - Achieved Level and Some Recommendation for Improving their Relevance

Directory of Open Access Journals (Sweden)

Ksenija Denčić-Mihajlov

2016-04-01

Full Text Available Purpose – This paper investigates mandatory and voluntary disclosure practices of non-financial listed companies on the Belgrade Stock Exchange. The results help in determining the level of transparency of Serbian s listed companies and in formulating recommendations for improving the quality and relevance of disclosed information. Design/methodology/approach – We focus on modeling both mandatory and voluntary disclosure indices for financial and non-financial information in order to evaluate the level of disclosure of 63 Serbian companies for reporting period 2012. Findings – We found the low level of both mandatory and voluntary disclosures. Concerning mandatary disclosure, the information that is least frequently disclosed by the sample companies are those related to the material content of the financial statements (information on changes in accounting estimates and corrections of fundamental errors in the previous period, as well as related companies. Serbian companies usually disclose information that contributes to their greater visibility. Similar to the mandatory disclosure, usually published voluntary information are mostly "neutral" from the point of impact on the values reported in the financial statements, which do not contribute to a better understanding of the financial position, profitability and cash flows of the company. Research limitations/implications – There is a limitation concerning the sample size (which is generally intrinsic to Serbian capital market size and the sample structure (research is limited to listed non-financial companies. The study covers the annual reports for 2012 which in Serbia coincides with a crisis period. The same research methodology could be applied on a larger and comprehensive database (non-listed companies and include period after 2012, which will allow the analysis of evolution of disclosure practices by companies within new accounting framework. Originality/value – The authors give

Application of multi-criteria analysis and GIS in ecotourism development (Case study: Serbian Danube region

Directory of Open Access Journals (Sweden)

Stojković Sanja

2015-01-01

Full Text Available Ecotourism can be defined as responsible travel to natural areas that conserves the environment and cultural heritage and improves the well-being of local people. Sustainable planning and management of ecotourism development are important and necessary for increasing positive and decreasing negative effects on the complex environment. This paper analyses the suitability of selected protected natural areas in the Serbian Danube region for the purposes of ecotourism development. The multi-criteria analysis includes several natural and socio-economic factors and criteria which influence ecotourism development. The integration of Geographic Information System (GIS and Analytic Hierarchy Process (AHP greatly facilitates the decision-making process in the ecotourism destination planning. A suitability map of the analysed protected natural areas for ecotourism development as one of the sustainable tourism types is highlighted as a result of this paper. Such analysis assists in the objective promotion of ecotourism destinations and thus contributes to the improvement of Serbian tourism development. [Projekat Ministarstva nauke Republike Srbije, br. 176008

The estimation of long-run relationship between Serbian and German economic growth

Directory of Open Access Journals (Sweden)

Nikolić Ivan

2016-01-01

Full Text Available Germany has always had an essential influence on Serbia's economic development. Today, Germany is Europe's economic and political superstar so this is even more pronounced. Hence, the aim of this paper is to explore the fundamental causal relationship between German and Serbian economy. In doing so, after the introductory part, where we emphasized interconnection in terms of investment, foreign trade, employment, new technologies etc., we are extending our study using quarterly 2004q1-2015q2 GDP data of both Serbia and Germany to estimate the Vector Error Correction model (VECM. The results suggest that there is co-integration between Serbia's and Germany's economic growth. The statistically significant negative coefficient on êt-1 indicates that Serbian GDP responds to a temporary disequilibrium between the Germany and Serbia. On the other hand, Germany does not appear to respond to a disequilibrium between the two economies; the t-ratio on êt-1 is statistically insignificant. These results support the idea that economic conditions in Serbia depend on those in Germany incomparably more than conditions in Germany depend on Serbia. Despite a solid long-term impact, there is not short run causality running from GerGDP to SrbGDP.

Socioeconomic Inequalities in Mental Health of Adult Population: Serbian National Health Survey.

Science.gov (United States)

Santric-Milicevic, Milena; Jankovic, Janko; Trajkovic, Goran; Terzic-Supic, Zorica; Babic, Uros; Petrovic, Marija

2016-01-01

The global burden of mental disorders is rising. In Serbia, anxiety is the leading cause of disability-adjusted life years. Serbia has no mental health survey at the population level. The information on prevalence of mental disorders and related socioeconomic inequalities are valuable for mental care improvement. To explore the prevalence of mental health disorders and socioeconomic inequalities in mental health of adult Serbian population, and to explore whether age years and employment status interact with mental health in urban and rural settlements. Cross-sectional study. This study is an additional analysis of Serbian Health Survey 2006 that was carried out with standardized household questionnaires at the representative sample of 7673 randomly selected households - 15563 adults. The response rate was 93%. A multivariate logistic regression modeling highlighted the predictors of the 5 item Mental Health Inventory (MHI-5), and of chronic anxiety or depression within eight independent variables (age, gender, type of settlement, marital status and self-perceived health, education, employment status and Wealth Index). The significance level in descriptive statistics, chi square analysis and bivariate and multivariate logistic regressions was set at pinequalities contributed by differences in age, education, employment, marriage and the wealth status of the adult population.

Degradation of landscape in Serbian ski resorts-aspects of scale and transfer of impacts

Directory of Open Access Journals (Sweden)

Ristić Ratko

2009-01-01

Full Text Available The environmental impacts in Serbian ski resorts (Kopaonik, Zlatibor, Stara planina, Divčibare are very strong, leading to degradation of unique mountain landscape, and functionality losses. Processes of urbanization, construction or improvement works, cause hard degradation of topsoil and native vegetation. The logging, large excavation activities, erosion, noise and water pollution constantly impact the habitats of all animal and plant species residing in small areas. The process leads to severe fragmentation of the remaining old-growth forests, endangering future subsistence. Consequences of mismanagement in ski areas are noticeable in downstream sections of river beds, causing floods and bed-load deposition, with high concentration of pollutants, in reservoirs for water supply. Legal nature-protection standards are weakly implemented in regional ski areas. Effective protection of landscape in Serbian ski-areas is based on careful considerations of impact assessment at all levels of planning (spatial and urban planning and designing activities, which enables application of restoration concept, in accordance with general goals of environmental protection (preserving biodiversity, CO2 sequestration, attenuation of effects of global climate changes.

Impact of the Serbian Banking Regulatory Framework Development on the Economic Growth of Serbia

Directory of Open Access Journals (Sweden)

Nenad Milojević

2013-04-01

Full Text Available The dynamic relationship between the banking regulatory framework and Basel capital standards, on the one side and economic growth and other macroeconomic indicators on the other side, attracts international academic and business circles for many years. Perceived from the Serbian perspective, the impact of the banking regulation development, or the Basel standards application, on economic growth is one of the most actual issues, especially since Serbia starting from December 31st 2011, began the Basel II application. The fact that the National Bank of Serbia and the Serbian commercial banks, gradually directed attention to more actual Basel III standard, further increasing the importance of the topic that this paper will be addressed. Quantitative and qualitative analyzes that were performed during the research presented in this paper indicate a significant potential for further positive effects, including economic growth, due to the implementation of Basel standards in Serbia. Positive results of application largely depend on adequate preparation, analysis and actions of all relevant parties in Basel standards implementation.

Investor relations on the internet: Analysis of companies on the Serbian stock market

Directory of Open Access Journals (Sweden)

Đorđević Bojan

2012-01-01

Full Text Available Stockholders and other interested parties used to exchange information in writing by means of physical submission, while today with just a click on any known company’s Internet page it is possible to acquire both the information needed and its financial situation. The aim of this work is to indicate the lack of corporate culture and investor communication on the Serbian stock market by analyzing investor relations via the e-communication tools of some of the best Serbian companies. This study investigates investor relations on the Internet of companies listed on the Belgrade Stock Exchange (BELEX 15 and BELEX LINE. For this purpose, the websites of the 20 largest listed companies of the Republic of Serbia were screened for investor relations items. Results obtained by using a three-stage model show that most companies in Serbia are at the second stage of internet investor relations, i.e., where information available through other sources is combined to better inform investors. In the third stage companies use the full interactive possibilities of the Internet for investor relations purposes. The author also stresses that the quality of investor relations must be a part of every company’s strategic vision.

Continuous-infusion adriamycin

International Nuclear Information System (INIS)

Benjamin, R.S.; Chawla, S.P.; Ewer, M.S.; Hortobagyi, G.N.

1986-01-01

This chapter discusses the diminished cardiotoxicity as well as diminished nausea and vomiting with continuous infusions of adriamycin to patients undergoing radiation therapy, particularly with infusions of 48 hours or longer, and best with 96-hour infusions, the longest duration that has been studied systematically. In breast cancer, data show that more adriamycin is better, but only for a selected subgroup of patients: those with complete remission. The diminished cardiotoxicity makes the use of adriamycin more attractive in the adjuvant situation, where increased safety will decrease the chances of long-term complications and make retreatment easy for cured patients who develop second malignancies

Work Engagement in Serbia: Psychometric Properties of the Serbian Version of the Utrecht Work Engagement Scale (UWES

Directory of Open Access Journals (Sweden)

Ivana B. Petrović

2017-10-01

Full Text Available Work engagement is defined as a positive, affective-motivational state of work-related well-being characterized by vigor, dedication and absorption. The Utrecht Work Engagement Scale (UWES is the most frequently used measure of work engagement. The aim of this study was to analyze the psychometric properties of the Serbian versions of the UWES-17 and UWES-9. The sample consisted of 860 employees from a number of organizations and jobs across Serbia. Based on the UWES-17 findings, the data confirm both the three-factor and one-factor solutions by giving a slight advantage to the three-factor solution. As for the UWES-9, based on the PCFA and CFA, the one-factor solution was obtained as the preferred one. Taking into account the UWES-9 reliability and correlation patterns of its subscales with other well-being variables, both one- and three-factor solutions of the UWES-9 are suggested for future research. Serbian versions of both the UWES-17 and UWES-9 have satisfactory psychometric properties with high reliability, factorial structure in line with the theoretical model, and good predictive validity. The study contributes to enhanced understanding of work engagement by offering an insight from the Serbian cultural and economic context, significantly different from the UWES originating setting. There is still a need for exploring how employees from Serbia conceptualize work engagement, as well as for further, more stringent investigating of the cultural invariance of the UWES factorial structure.

Work Engagement in Serbia: Psychometric Properties of the Serbian Version of the Utrecht Work Engagement Scale (UWES).

Science.gov (United States)

Petrović, Ivana B; Vukelić, Milica; Čizmić, Svetlana

2017-01-01

Work engagement is defined as a positive, affective-motivational state of work-related well-being characterized by vigor, dedication and absorption. The Utrecht Work Engagement Scale (UWES) is the most frequently used measure of work engagement. The aim of this study was to analyze the psychometric properties of the Serbian versions of the UWES-17 and UWES-9. The sample consisted of 860 employees from a number of organizations and jobs across Serbia. Based on the UWES-17 findings, the data confirm both the three-factor and one-factor solutions by giving a slight advantage to the three-factor solution. As for the UWES-9, based on the PCFA and CFA, the one-factor solution was obtained as the preferred one. Taking into account the UWES-9 reliability and correlation patterns of its subscales with other well-being variables, both one- and three-factor solutions of the UWES-9 are suggested for future research. Serbian versions of both the UWES-17 and UWES-9 have satisfactory psychometric properties with high reliability, factorial structure in line with the theoretical model, and good predictive validity. The study contributes to enhanced understanding of work engagement by offering an insight from the Serbian cultural and economic context, significantly different from the UWES originating setting. There is still a need for exploring how employees from Serbia conceptualize work engagement, as well as for further, more stringent investigating of the cultural invariance of the UWES factorial structure.

Attitudes toward Shock Advertising of Western-European and Serbian University Students With Regard To Public Health Context (Anti-Smoking and Anti-HIV/AIDS Campaigns)

OpenAIRE

Krstic, Tamara

2007-01-01

The main objective of this dissertation is to examine attitudes toward shock advertising of western-European and Serbian university students with regard to public health context (anti-smoking and anti-HIV/AIDS campaigns). Although the use of shock advertising is widely adopted in practice, there has not been extensive research with regard to this topic. Public health context is of special interest in this dissertation as there is an urge for social marketing on Serbian market. The results of ...

Mergers and concentrations occurring on the basis of acquiring of control in Serbian and EU competition law

Directory of Open Access Journals (Sweden)

Fišer-Šobot Sandra S.

2016-01-01

Full Text Available Relevant Serbian and EU competition legislation does not define what is considered a concentration, but regulates which business transactions lead to concentrations of undertakings. Concentrations can be differentiated according to whether the concentration affects legal position of the merging undertakings. A concentration shall be deemed to arise where a change of control on a lasting basis results from the merger of two or more previously independent undertakings or parts of undertakings. Second type of concentrations occurs in the case of an acquisition of control. Finally, the concentration shall be deemed to arise in the case of creation of a joint venture performing on a lasting basis all the functions of an autonomous economic entity. This paper analyses mergers and concentrations occurring on the basis of acquiring of control in Serbian and EU competition law.

Thrombolytic treatment for acute ischemic cerebral stroke: intraarterial urokinase infusion vs. intravenous heparin and urokinase infusion

International Nuclear Information System (INIS)

Ko, Gi Young; Suh, Dae Chul; Lee, Jae Hong; Kim, Jun Hyoung; Choi, Choong Gon; Lee, Ho Kyu; Lee, Myoung Chong

1996-01-01

To evaluate the efficacy and limitation of intra-arterial urokinase (IAUK) infusion for treatment of acute cerebral stroke. Twenty-seven acute cerebral stroke patients treated with IAUK infusion within six hours of stroke onset were reviewed. All patients showed normal initial brain findings on CT. In 21 patients, urokinase(5-15 x 10 5 IU) was administered through a microcatheter placed into or proximal to occluded segment. Mechanical disruption of thrombus by guidewire was performed in 17 patients. Angiographic and clinical responses and complications after IAUK infusion, were evaluated and the results were compared with those of intravenous heparin(N=19) and urokinase infusion(N=19). Complete or partial angiographic recanalization of occluded segment was found in 18 patients (67%), and neurologic improvement was followed in 14 patients(52%). The degree of improvement on the stroke scale score after IAUK infusion was statistically more significant(p<0.05) than that shown after intravenous heparin and urokinase infusion. Complications after IAUK infusion were large(15%) and small amount intracerebral hemorrhage(15%), contrast leakage into brain parenchyma(11%), and gastrointestinal bleeding(4%). Between the IAVK and the intravenous urokinase infusion group, differences in extent and types of complications were statistically insignificant, but were significantly higher in those two groups than in the intravenous heparin infusion group. IAUK infusion may be effective for the treatment of acute cerebral stroke

Abstract legal effect of juridical acts in European and Serbian law

Directory of Open Access Journals (Sweden)

Dudaš Atila

2012-01-01

Full Text Available In this paper the author gives an overview of the development from abstract to causal juridical acts and explains the abstract legal effect of juridical acts in present-day European civil law (in the law of Germany, Austria, Switzerland and France. He concludes that in contemporary law juridical acts cannot have full abstract legal effect, as in archaic legal orders, because modern legal orders do not allow the creation of claims and debts in a way that entirely excludes the possibility to scrutinize whether a juridical act is null and void for the infringement of public order by its aim. In relation to the law of Serbia, the author refers to the difference between juridical acts that create obligations, that is claims and debts, and acts by which the parties merely dispose of the claims and debts already imposed. This division of juridical acts has its origins in the German legal culture, but it is fairly applicable to the Serbian law, as well. The author points out that the requirement of the Law on obligations, that all juridical acts must have a valid cause, applies without exception to juridical acts imposing an obligation (the so-called Verpflichtungsgeschäfte, regardless of whether they are concluded in the form of an abstract of causal act, i.e. whether the purpose of the transaction is determinable from their content. In this context he refers to the standpoint adopted in the doctrine that the cause of juridical acts gains relevance by three means: by the agreement of the parties, objection of the respondent and when the court determines ex officio whether the contract is contrary to public order. The author supports the point of view that in Serbian law juridical acts aimed merely to disposing of claims and debts already imposed (the so-called Verfügungsgeschäfte may have a legal effect, which is independent from their cause. For these reasons, the author is of the opinion that in present-day legal orders, hence in Serbian law too

Subcutaneous insulin infusion: change in basal infusion rate has no immediate effect on insulin absorption rate

International Nuclear Information System (INIS)

Hildebrandt, P.; Birch, K.; Jensen, B.M.; Kuehl, C.

1986-01-01

Eight insulin-dependent diabetic patients were simultaneously given subcutaneous infusions (1.12 IU/h each) of 125 I-labeled Actrapid insulin in each side of the abdominal wall. After 24 h of infusion, the size of the infused insulin depots was measured by external counting for 5 h. The basal infusion rate was then doubled in one side and halved in the other for the next 4 h. Finally, 1.12 IU/h of insulin was given in both sides of the abdominal wall for an additional 3 h. The changes in the size of the depots were measured, and the absorption rates for each hour were calculated. During the first 5 h of infusion, the depot size was almost constant (approximately 5 IU) with an absorption rate that equaled the infusion rate. Doubling the infusion rate led to a significant increase in depot size, but the absorption rate remained unchanged for the first 3 h, and only thereafter was a significant increase seen. When the infusion rate was reduced to the initial 1.12 IU/h, the absorption rate remained elevated during the next 3 h. Correspondingly, when the infusion rate was decreased, the depot size also decreased, but the absorption rate remained unchanged for the first 3 h. The results show that a change in the basal insulin infusion rate does not lead to any immediate change in the insulin absorption rate. This should be considered when planning an insulin-infusion program that includes alteration(s) in the basal-rate setting

Total protein and lipid contents of canned fish on the Serbian market

OpenAIRE

Marković Goran; Mladenović Jelena; Cvijović Milica; Miljković Jelena

2015-01-01

Total protein and lipid contents were analysed in 5 samples of canned fish (sardines, Atlantic mackerel fillets, tuna in olive oil, smoked Baltic sprat and herring fillets) available on the Serbian market. Standard methods for the determination of protein (Kjeldahl method) and lipid (Soxhlet method) contents were used on drained samples. The protein content was 21.31% on average, with a range of 18.59% - 24.17%. Total lipids showed considerably large variations (5.49% - 35.20%), and averaged ...

Chasmophytic forests of Ostrya carpinifolia in west-Serbian canyons

Directory of Open Access Journals (Sweden)

Karadžić, B.

2017-09-01

Full Text Available Variability patterns and biodiversity components of chasmophytic forests of Ostrya carpinifolia in westSerbian ravine habitats were analyzed in this article. Investigations were performed in four gorges along Gornja Trešnjica, Gradac, Ljutina and Lim rivers. Chasmophytic hop hornbeam forests occur on steep slopes (25° to 50° at elevations ranging from 260 m to 1200 m, on all aspects. These forests grow on screes, rocky clifs, colluvial gravel, on shallow soils on dolomites, limestone and serpentine. Canonical correspondence analysis indicates that moisture, light and temperature gradients are the main factors affecting diversification of investigated forests. The greatest alpha diversity was detected in Brodarevo and Gostun gorges, along the Lim River.

Restoration of eroded surfaces in Serbian ski-areas

Directory of Open Access Journals (Sweden)

Ristić Ratko

2009-01-01

Full Text Available The environmental impacts in Serbian ski areas are very strong, leading to landscape degradation and functionality losses. Construction or improvement works cause serious destruction of topsoil and native vegetation. Some activities enhance erosion production and sediment yield: clear cuttings; trunk transport down the slope; road construction and large excavations. Also, lack of erosion control works in ski areas, especially between April and October, result in various forms of land degradation such as furrows, gullies, landslides, or debris from rock weathering. The consequences of mismanagement in ski areas are noticeable in downstream sections of river beds, causing floods and bed-load deposition. Planning and designing activities, with the application of technical and biotechnical erosion control structures, through the concept of restoration, are necessary measures in the protection of ski areas.

Shadow of the Brussels Agreement over the Republic of Srpska: The way term 'betrayal' appeared in Serbian national discourse

Directory of Open Access Journals (Sweden)

Reljić Slobodan

2013-01-01

Full Text Available After signing of the Brussels Agreement (April, 2013 and the beginning of the more rapid giving away of the national territory's 15% without resistance, the government in Belgrade is facing issues raised by the public: Is the Republic of Srpska next part of the national corps that is going to be systematically renounced of, for the sake of shady promises by the West to join the European Union? Geopolitical relations in which the entire process is taking place suggest new perception of 'Serbian question's' solving. In Serbian national discourse a standing point has occurred that radicalizes the public opinion additionally - national betrayal. That puts the government and the public opinion in front of a dilemma: more authoritarianism or more rapid disorganization.

Infusion MR arteriography during hepatic arterial infusion chemotherapy. Evaluation of clinical usefulness

International Nuclear Information System (INIS)

Uchino, Minako; Takizawa, Kenji

2003-01-01

We developed a new method of infusion MR arteriography (IMRA) via an implantable port system using an infusion pump for the evaluation of drug distribution during hepatic arterial infusion chemotherapy. The purposes of this study were to optimize the method and evaluate its clinical usefulness. We used 3D-T1 turbo field echo (TFE) as the most suitable sequence for IMRA according to the results of a phantom model experiment. We examined 33 cases of liver cancer that had been treated by arterial infusion chemotherapy via the port system. The following investigations were performed: degree of tumor enhancement, intra- and extra- hepatic perfusion abnormality, and related toxicity. The evaluation of images was performed separately by two radiologists. IMRA provided good images of contrast enhancement, to reveal the perfusion patterns. The treatment response rate in the tumor group with well enhancement was higher than that of the group with poor enhancement (p<0.0001). Extrahepatic perfusion was well visualized and was correlated with toxicity (p<0.0001). IMRA is a useful method to evaluate drug perfusion for the optimization of arterial infusion chemotherapy. (author)

From a reading devoted monk to an idealist prompter: the Serbian Quixotes across the centuries

Directory of Open Access Journals (Sweden)

Jasna Stojanović

2012-12-01

Full Text Available In this paper we analyze the characters of several Serbian novels published from the Enlightenment to the present day, whose main characters show obvious resemblances with Cervantes’ Don Quixote: Dositej Obradović´s Život i priključenija (1783, Jovan Sterija Popović´s Roman bez romana (1838, various novels of Jakov Ignjatović (Večiti mladoženja, 1878; Vasa Rešpekt, 1875; Milan Narandžić, 1860-1862, and Sančova verzija by Ratomir Damjanović (1999. We analyze their personalities, pointing out the similarities with their model and then exploring the differences or particularities emanating from either the author’s style, the period of its creation and/or the poetics of the Serbian literature. Our goal is to investigate the manner and the level in which the Cervantine legacy has been creatively transformed and what constant characteristics of the personality of Don Quixote have resisted the passage of time.

Similarities and Differences between the Romanian and Serbian Proverbs. Vuk Stefanovic Karadzic and Anton Pann

Directory of Open Access Journals (Sweden)

Virginia POPOVIĆ

2011-01-01

Full Text Available Sayings and proverbs are the elements of spirit and wisdom of a people, represent the force of thought and metaphor, intelligence and spiritual wisdom, the power of observation, the truths of skills argumentation and to explore life, the power of language to express much in few words. From everything that exists in literary creation, a particular difficulty lies in translating sayings and proverbs from one language to another. From what has created in the whole literary work, a particular challenge is to translate the sayings and proverbs from one language to another. Romanian and Serbian reflects very well the virtues which are adapted to express sayings and proverbs, communicate more in a few words say more than what is said with words, if that partner has the satisfaction to decipher the intentions of the author. Both pickers’ sayings, Vuk Karadzic and Anton Pann have desire as their collections through this remember the sayings and proverbs Serbian and Romanian, and contributed to their entry into our everyday language, and gave the magnitude and expressiveness.

Assessment of possible association between rs378854 and prostate cancer risk in the Serbian population

Directory of Open Access Journals (Sweden)

Brajušković G.

2013-01-01

Full Text Available Prostate cancer (PCa is the second most commonly diagnosed cancer among men worldwide. Despite its high incidence rate, the molecular basis of PCa onset and its progression remains little understood. Genome-wide association studies (GWAS have greatly contributed to the identification of single nucleotide polymorphisms (SNP associated with PCa risk. Several GWAS identified 8q24 as one of the most significant PCa-associated regions. The aim of this study was to evaluate the association of SNP rs378854 at 8q24 with PCa risk in the Serbian population. The study population included 261 individuals diagnosed with PCa, 257 individuals diagnosed with benign prostatic hyperplasia (BPH and 106 healthy controls. Data quality analysis yielded results showing deviations from Hardy-Weinberg equilibrium in groups of PCa patients and BPH patients as well as in the control group. There was no significant association between alleles and genotypes of the genetic variant rs378854 and PCa risk in the Serbian population. [Projekat Ministarstva nauke Republike Srbije, br. 173016

An audit of hospital based outpatient infusions and a pilot program of community-based monoclonal antibody infusions.

LENUS (Irish Health Repository)

Doran, J-P

2012-02-01

INTRODUCTION: Infliximab, a chimeric monoclonal antibody to tumour necrosis factor alpha, is administered as an intravenous infusion requiring a costly hospital day case or inpatient admission. METHODS: An audit of all current therapies given by intravenous infusions in an outpatient setting in St Vincent\\'s University Hospital (SVUH) was undertaken. Furthermore, in conjunction with TCP homecare, we established in a general practise health clinic, the first Irish community infusion centre for the administration of infliximab in August 2006. RESULTS: All outpatient departments indicated that they would favour a centralized hospital infusion unit. There were no adverse events and the mean global satisfaction improved in the community infliximab infusion pilot programme of seven patients. CONCLUSION: This study suggests efficiencies in providing centralized infusion facilities, while the community based infusion of infliximab is feasible and safe in this small cohort and identifies the community infusion unit as a viable and cost efficient alternative for administration of infliximab.

Fumonisins production potential of Fusarium verticillioides isolated from Serbian maize and wheat kernels

Directory of Open Access Journals (Sweden)

Krstović Saša Z.

2017-01-01

Full Text Available The production of fumonisins by potentially toxigenic Fusarium verticillioides isolates originating from Serbian maize and wheat kernels was tested in vitro. A total of six F. verticillioides isolates were incubated on yeast extract sucrose medium (YESA for 4 weeks at 25 °C in the dark. Their toxin production potential was tested by applying a modified HPLC method for determination of fumonisins in cereals, since the TLC method gave no results. Analyses were performed on a HPLC-FLD system after sample extraction from YESA and extract cleanup on a SPE column. Although the isolates were tested for fumonisin B1, B2 and B3, only fumonisin B1 was detected. The results showed that all tested isolates had toxigenic potential for fumonisin B1 production. The average fumonisin B1 production of the isolates ranged from 7 to 289 μg/kg, thus indicating a highly variable toxigenic potential among the isolates. Isolate 1282 expressed the highest toxigenic potential for fumonisin B1 production (289 μg/kg, while isolate 2533/A showed a questionable potential for fumonisin production (7 μg/kg. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. TR 31023

Bronchial arterial infusion versus bronchial combined pulmonary arterial infusion for pulmonary metastatic tumors

International Nuclear Information System (INIS)

Dong Sheng; Dong Weihua; Jia Ningyang; Zhang Dianbo; Xiao Xiangsheng

2008-01-01

Objective: To evaluate the pulmonary metastatic tumor response to different ways of transcatheter arterial infusion. Methods: Thirty-five patients with pulmonary metastatic tumors were randomized divided into two groups: 15 patients with 49 lesions treated with bronchial arterial infusion (BAI) and 20 patients with 65 lesions treated with bronchial arterial infusion (BM)combined with pulmonary arterial infusion (PAI). The therapeutic response was assessed by the WHO evaluation criteria. Results: The total effective rate(CR + PR) of BAI was 65.3% (32/49), PAI + BAI was 61.5%(40/65) showing no statistical difference. The median survival time of BAI was 9 mo, BAI + PAI was 11.5 mo, demonstrating no statistical significance. Conclusions: BAI should be the primary treatment for pulmonary metastatic tumor. (authors)

Direct results of recent multidisciplinary ethno-genetic research of the Serbs and the Serbian population (in Aleksandrovac district

Directory of Open Access Journals (Sweden)

Todorović Ivica

2014-01-01

Full Text Available The paper presents immediate results of a multidisciplinary research into ethno genesis, that is, the origin of the Serbs and the Serbian population, based on genetic indicators. The most direct results of the carried out survey are 85 haplotypes with 17 DYS markers/locuses of the respondents from Aleksandrovac district, a representative area as it is in the very centre of Serbian, Kosovo-Resava linguistic and cultural zone. Unlike previous texts that the authors have written on this subject, this paper, for the first time, presents actual results which correlate ethnological facts - starting from older up to latest records on origin - with genetic results obtained owing to the cooperation of the SASA Institute of Ethnography and the Laboratory for DNA analysis of the National forensic centre at the Ministry of Interior, Republic of Serbia. In this way, new findings, which could have been summoned only by parallel use of ethnological and genetic information (and which are given in the paper as clear proofs of necessity and effectiveness of the applied methodological approach, are being obtained and presented. Among other things, the given results of the preliminary survey (compared with the latest relevant surveys by other authors and institutions indicate the dominance of 12a and R1a haplogroups, decisive in the ethnogenesis of the Slavs, which matches common Serbian perception of the Serbs as of a nation of the Slav language and origin.

Anthropocentric language theory and Serbian case systems

Directory of Open Access Journals (Sweden)

Topolinjska Zuzana

2002-01-01

Full Text Available The author understands case as a relationship of syntactic dependence between a subordinated noun phrase and the governing syntactic construction (predicative expression and/or another noun phrase. The above definition construes case as a universal category characteristics of all the languages sharing the nomen vs verbum opposition. Particular cases are conceived as primarily semantically motivated. The two relevant semantic parameters are /+/ -human / (or /+/ -animated/ and /+/ -localized/, i. e. - in other words - the so-called hierarchy of animateness and the spatial location of the objects that the corresponding noun phrases refer to. N and D are being characterized as /+ hum/, A and I as /-hum/ and L as belonging to another semantic paradigm is defined simply as /+ loc/. Results of the analyses of morphological syncretism's and of syntactic exponents of the NPs-dependence found in Serbian case systems support the above tentative interpretation of the case as a (semantic and syntactic category.

[Epilepsy treatment in Serbian medieval monastery hospitals].

Science.gov (United States)

Ilić-Tasić, Slobodanka; Pantović, Mihailo; Jović, Nebojsa; Ravanić, Dragan; Obradović, Dejan; Sretenović, Srdjan; Pantović, Maja; Pantović, Vesna

2009-01-01

Emperor John III Ducas Vatatzes (ruled from 1222-1254) and his son Theodore II Lascaris (ruled from 1254-1258) both suffered from epilepsy. On his journeys to Nicaea, St Sava visited emperors Theodore I Lascaris (ruled from 1204-1222) and John II Vatatzes, who richly rewarded him, which was probably of crucial importance for the foundation of hospitals in the Monastery of Hilandar and the Monastery of Studenica These hospitals had special departments for the treatment of patints with epilepsy. According to researches conducted up-to-date, these departments are considered to be the oldest institutions for epilepsy treatment. Monastery hospitals in the West served primarily as a shelter for the poor and patients with chronic incurable diseases. The development of Serbian monastery hospitals was a long process and it included institutions that lasted for a long time (for over two centuries) in which, among others, those affected by epilepsy were cured.

Motives for food choice among Serbian consumers

Directory of Open Access Journals (Sweden)

Gagić Snježana

2014-01-01

Full Text Available People's motives for food choice depend on a number of very complex economic, social and individual factors. A Food Choice Questionnaire (FCQ, an instrument that measures the importance of factors underlying food choice, was used to reveal the Serbian consumers' food choice motives by survey of 450 respondents of different age groups. A confirmatory factor analysis was conducted on the motive items, using 11 factors. Previous research shows that the nutrition in Serbia is not balanced enough, and therefore the analysis of motives for food choice is considered a useful tool for the planning of more efficient public policies and interventions aimed at influencing healthier eating habits. Hence the results can be useful for researchers as well as for public institutions which deal with creating the strategy of public health or businessmen who produce and sell food products, because knowing consumer behaviour is necessary for product success on the market.

Mineral Composition of Selected Serbian Propolis Samples

Directory of Open Access Journals (Sweden)

Tosic Snezana

2017-06-01

Full Text Available The aim of this work was to determine the content of 22 macro- and microelements in ten raw Serbian propolis samples which differ in geographical and botanical origin as well as in polluted agent contents by atomic emission spectrometry with inductively coupled plasma (ICP-OES. The macroelements were more common and present Ca content was the highest while Na content the lowest. Among the studied essential trace elements Fe was the most common element. The levels of toxic elements (Pb, Cd, As and Hg were also analyzed, since they were possible environmental contaminants that could be transferred into propolis products for human consumption. As and Hg were not detected in any of the analyzed samples but a high level of Pb (2.0-9.7 mg/kg was detected and only selected portions of raw propolis could be used to produce natural medicines and dietary supplements for humans. Obtained results were statistically analyzed, and the examined samples showed a wide range of element content.

Compliance of the legal treatment of experimental animals in Serbian legislation with the legislation of the European Union

Directory of Open Access Journals (Sweden)

Vidić-Trninić Jelena

2013-01-01

Full Text Available The author focuses on compliance of the legal treatment of experimental animals in Serbian law with the provisions of the European legislation. Analysing, on one hand, the treatment that experimental animals have under the law of European Union, and on the other hand, the treatment that they have in the law of Serbia, in accordance with the relevant acts and subordinate legislation acts, this article seeks to answer the question whether the degree of legal protection of experimental animals in domestic law is satisfactory, as well as whether and to what extent the relevant national legislation complies with the European standards. At the same time, the article attempts to point out the appropriate measures necessary to be taken in the future in order to achieve as high quality and comprehensive protection of experimental animals as possible in Serbian law.

Causal-implicative relationships in the Serbian hypotaxis (Complex of generative complex sentences

Directory of Open Access Journals (Sweden)

Vojvodić Dojčil P.

2015-01-01

Full Text Available The paper analyzes the causal-implicative relationships in the segmented complex sentences with a “closed” (asymmetric, mandatory bi-situational generative (conditional semantic structure on the corpus of the Serbian language. The generative (conditional semantic structure consists of meaningfully interconnected antecedents and consequents that are based on the principle of subordination. These sentences are characterized with a general causal link due to the specific implicative relationship between the segments that can be realized within dependent clauses with diverse categorically-differential semantics (i.e. causal, consecutive, final, conditional and concessive. The author reaches a conclusion that the given implicative relationships (P ⇒ Q, P ⇐ Q/Q ⇒ P, P ⇔Q, P ⇒ Q´ Δ P´ ⇒ Q represent, in fact, semantic invariants of generative complex sentences. It is pointed out that the structure, formation and functioning of these relationships (sentences are always determined by the interconnectedness of syntax and lexicon. They are based on a general causal adverbial meaning of the conjunctions in a subordinate clause, which are also used to determine the adverbial semantics of a sentence as a whole. The article discusses in particular the aspectual-temporal correlations that are realized in complex sentences with a generative structure. It has been noted very often in the literature that there is no differentiation made among all of the types of the hypothetical conditionality - real, eventual, potential and unreal. The paper analyzes taxis of simultaneity and succession (anteriority/posteriority of the main and subordinate clause predicates in conditional sentences as a special type of the relative-temporal relationships within the same temporal plan. In order to interpret these correlations, the Serbian data was compared to the data in Russian and Polish. It is noted that the Northern Slavic languages (in this case Russian and

Effect of steel and teflon infusion catheters on subcutaneous adipose tissue blood flow and infusion counter pressure in humans

DEFF Research Database (Denmark)

Højbjerre, Lise; Skov-Jensen, Camilla; Kaastrup, Peter

2009-01-01

BACKGROUND: Subcutaneous tissue is an important target for drug deposition or infusion. A local trauma may induce alterations in local microcirculation and diffusion barriers with consequences for drug bioavailability. We examined the influence of infusion catheters' wear time on local...... microcirculation and infusion counter pressure. METHODS: One steel catheter and one Teflon (Dupont, Wilmington, DE) catheter were inserted in subcutaneous, abdominal adipose tissue (SCAAT) in 10 healthy, lean men. The catheters were infused with isotonic saline at a rate of 10 microL/h for 48 h. Another steel...... catheter and a Teflon catheter were inserted contralateral to the previous catheters after 48 h. The infusion counter pressure was measured during a basal infusion rate followed by a bolus infusion. The measurements during a basal rate infusion were repeated after the bolus infusion. Adipose tissue blood...

FINANCIAL ASPECTS OF CURRENT ASSETS MANAGEMENT IN SERBIAN ECONOMY

Directory of Open Access Journals (Sweden)

Jugoslav Aničić

2017-04-01

Full Text Available Efficient current assets management should provide optimum level of company’s net current assets as interrelation between current assets and short-term liabilities. The companies whose short-term liabilities are not proportionate to cashable current assets face the problem of insolvency and all negative consequences caused by insolvency. Rate of return to total assets measures how good is the management’s use of the company property for the purpose of creating operating profit, regardless of the fact how these assets are financed. Serbian economy is burdened by insolvency and significant indebtedness under unfavorable loan terms, so adequate attention has to be dedicated to the matters of the structure of operating property and its financing in order to improve competitiveness and efficiency of business.

Members of young Bosnia between Serbian and Yugoslav identity

Directory of Open Access Journals (Sweden)

Mastilović Draga

2014-01-01

Full Text Available Although they were considered the ideologists of Yugoslav identity before the First World War, the members of Young Bosnia were not united regarding this issue. This is illustrated by the attitudes of the two main ideologists of the movement Vladimir Gaćinović and Dimitrije Mitrinović. Contrary to Mitrinović, who was one of the most eager promoters of the idea of the unity of the South Slavs, Gaćinović was distrustful of this idea. He understood it as the 'pouring Croatian water in Serbian wine'. Both of them had a big number of followers in students' revolutionary organizations, and these Serb-Croat and Yugoslav organizations were responsible for the Assassination at Sarajevo.

Applicability of a Serbian version of the “Oral Impacts on Daily Performance (OIDP” index - assessment of oral health-related quality of life

Directory of Open Access Journals (Sweden)

Stančić Ivica

2012-01-01

Full Text Available Background/Aim. The Oral Impacts on Daily Performance (OIDP is a well-known psychometric test used internationally to assess the oral health-related quality of life. The interview and self-administrated questionnaire both assess the degree to which oral health problems have affected the life of the participants over the previous 6 months. The aim of this study was to translate the OIDP index into Serbian and to assess its reliability in practice as its initial verification in the Serbian speaking area. Methods. Following an internationally established methods, the OIDP scale was translated using standardized methodology that consisted of forward translation, pilot study and backward translation. Results. A pilot study was carried out with 44 respondents (24 males i 20 females using a preliminar Serbian version of the OIDP index. All patients were aged over 65 years. A total of 68.2% of the participants replied that they had at least one OIDP impact on daily life in the past 6 months. These troubles were most prominent during eating (47.7% and speaking (36.4%, but there is a little impact of troubles in the domain of psychosocial sphere. The corrected item-total correlation coefficients for all items were above the minimum recommended level of 0.20 for including an item in a scale. The standardized Cronbach’s alpha coefficient was 0.75. Conclusion. Based on these results, we can conclude that this index is suitable for use in everyday practice in Serbian speaking area providing useful information required to assess oral health-related quality of life.

Reliability, construct and criterion-related validity of the Serbian adaptation of the trait emotional intelligence questionnaire (TEIQue

Directory of Open Access Journals (Sweden)

Jolić-Marjanović Zorana

2014-01-01

Full Text Available This paper presents evidence on the reliability and validity of the Serbian adaptation of the Trait Emotional Intelligence Questionnaire (TEIQue, an instrument designed to comprehensively assess emotional intelligence conceived as a constellation of emotionrelated self-perceptions. Study participants were 254 adults, who completed the Serbian TEIQue, NEO-FFI, MSCEIT, EQ-short, and RSPWB. The results indicate that the adapted TEIQue is a psychometrically sound assessment tool: internal consistencies were mostly acceptable at facet, generally good at factor, and excellent at whole-scale level; the fourfactor structure was confirmed by means of CFA; convergent-discriminant validity was established through meaningful associations with related constructs, indicating that trait EI is closely aligned with affect and self-efficacy related constructs from the realm of personality (i.e., E, N, C, and Empathy, but shows only moderate overlap with ability EI; finally, incremental validity was demonstrated in the prediction of psychological wellbeing, over and above the Big Five. [Projekat Ministarstva nauke Republike Srbije, br. 179018

Hippocampal infusions of glucose reverse memory deficits produced by co-infusions of a GABA receptor agonist.

Science.gov (United States)

Krebs-Kraft, Desiree L; Parent, Marise B

2008-02-01

Although septal infusions of glucose typically have positive effects on memory, we have shown repeatedly that this treatment exacerbates memory deficits produced by co-infusions of gamma-aminobutyric acid (GABA) receptor agonists. The present experiments tested whether this negative interaction between glucose and GABA in the medial septum would be observed in the hippocampus, a brain region where glucose typically has positive effects on memory. Specifically, we determined whether hippocampal infusions of glucose would reverse or exacerbate memory deficits produced by hippocampal co-infusions of the GABA receptor agonist muscimol. Fifteen minutes prior to either assessing spontaneous alternation (SA) or continuous multiple trial inhibitory avoidance (CMIA) training, male Sprague-Dawley-derived rats were given bilateral hippocampal infusions of vehicle (phosphate-buffered saline [PBS], 1 microl/2 min), glucose (33 or 50 nmol), muscimol (0.3 or 0.4 microg, SA or 3 microg, CMIA) or muscimol and glucose combined in one solution. The results indicated that hippocampal infusions of muscimol alone decreased SA scores and CMIA retention latencies. More importantly, hippocampal infusions of glucose, at doses that had no effect when infused alone, attenuated (33 nmol) or reversed (50 nmol) the muscimol-induced memory deficits. Thus, although co-infusions of glucose with muscimol into the medial septum impair memory, the present findings show that an opposite effect is observed in the hippocampus. Collectively, these findings suggest that the memory-impairing interaction between glucose and GABA in the medial septum is not a general property of the brain, but rather is brain region-dependent.

Crystallite size distribution of clay minerals from selected Serbian clay deposits

Directory of Open Access Journals (Sweden)

Simić Vladimir

2006-01-01

Full Text Available The BWA (Bertaut-Warren-Averbach technique for the measurement of the mean crystallite thickness and thickness distributions of phyllosilicates was applied to a set of kaolin and bentonite minerals. Six samples of kaolinitic clays, one sample of halloysite, and five bentonite samples from selected Serbian deposits were analyzed. These clays are of sedimentary volcano-sedimentary (diagenetic, and hydrothermal origin. Two different types of shape of thickness distribution were found - lognormal, typical for bentonite and halloysite, and polymodal, typical for kaolinite. The mean crystallite thickness (T BWA seams to be influenced by the genetic type of the clay sample.

Subcutaneous infusion in palliative care: a focus on the neria soft 90 infusion set.

Science.gov (United States)

Gabriel, Janice

2014-11-01

Subcutaneous administration of medications and/or fluids can play a crucial part in supporting patients at home and thereby avoiding the need for hospitalisation. It is an area of patient care that has received little attention compared with other types of parenteral therapies. However, it is an effective and safe route for continuous administration for individuals requiring palliative care. Technological advancements have led to improved subcutaneous infusion devices, such as fine-gauge cannulae with integral sharps protection, as well as integral hypoallergenic dressings. These design features not only help to increase patient comfort but also minimise the potential for needlestick injuries, as well as providing the health professional with one sterile package containing all of the components needed to establish subcutaneous infusion. However, technological developments alone are insufficient to improve patient outcomes. Knowledge of the individual patient, together with their diagnosis and intended treatment, will influence the choice of subcutaneous infusion device, with the overall aim of minimising the potential for complications and improving comfort. This paper provides an overview of subcutaneous infusion, including the importance of patient assessment and the education and training needs of health professionals, and then focuses on one specific subcutaneous infusion device: the neria soft 90 infusion set.

On-line Delivery for Serbo-Croatian (Bosniac, Croatian, Serbian: Tailoring Technology to the Learner

Directory of Open Access Journals (Sweden)

Danko Sipka

2004-01-01

Full Text Available Tbis paper discusses the project of full on-line delivery of an introductory Serbo-Croatian (Bosniac, Croatian, Serbian course at the Arizona State University Critical Languages Institute. The issue of tailoring technology to meet diversified needs of a wide range of learners (from heritage speakers of the three Serbo-Croatian speaking ethnic communities to professional non-heritage learners is in the center of the discussion.

Epidemiological characteristics of hepatitis A in Serbian areas of Kosovo and Metohia

Directory of Open Access Journals (Sweden)

Stevanović Jasmina

2016-01-01

Full Text Available Hepatitis A is an acute viral disease of the liver caused by the hepatitis A virus (HAV .In many areas of the world represents a significant epidemiological problem, and the infection is usually transmitted by contact, rarely contaminated water and food. The main objective of the study was to identify the most important epidemiological characteristics of hepatitis A in Serbian areas of Kosovo and Metohija. We used the data of reporting of infectious diseases, reports on infectious diseases (seven-day, month, year of the Department of Public Health Pristina in Kosovska Mitrovica. In our research we used epidemiological Studies of cross-section (cross-sectional. Between 2003-2015. in Kosovo and Metohija (Serbian middle registered 223 cases of hepatitis A. The average incidence in the reporting period was 11.03 / 10,0000. Analysis of age distribution revealed that the most common incidence in people aged 15-19 years, and the rarest people aged 50-59 years. Hepatitis A occurs throughout the year, showing seasonal variations. Trend of incidence shows a negative trend with a reduction in the number of cases in the territory of Kosovo and Metohija. Based on the results of our study we can conclude that hepatitis A is an important public health and socioeconomic problem. In order to prevent hepatitis A, it is important to continue to improve hygiene and sanitary conditions of life as the best general preventive measures.

The attractiveness of Serbian market in attracting international companies in tourism sector

Directory of Open Access Journals (Sweden)

Tornjanski Aleksandra

2015-01-01

Full Text Available The entry of international companies in the field of tourism in the domestic market creates a huge potential for its growth, greater involvement in the international tourism, flow of people and information as well as transfer of new technologies. Furthermore, international companies in the field of tourism develop tourism in the country they enter and it is therefore necessary to prepare the domestic market for their entry. Controlled and uncontrolled factors both have impact on the attractiveness of a country as a potential market and consequently affect its business operations. Various barriers to entry may be administrative and real (actual, thus affecting the development of market for entry and business operations of companies interested in internationalization in the field of tourism. The subject of this paper is to analyze the market entry barriers of Serbia faced by international companies in the field of tourism. The main objective of this paper is to evaluate if the Serbian market is attractive for entry of international companies in the field of tourism by analysis of its market entry barriers. The results show that the Serbian market still has to work to reduce market entry barriers, in order to become more attractive for entry of international companies in tourism. Manifold advantages of the global companies' entry in the market are that they are perceived as strong incentives for countries such as Serbia to develop their market and make it more accessible to enter.

Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer.

Science.gov (United States)

Yang, Lijun; Kress, Benjamin T; Weber, Harris J; Thiyagarajan, Meenakshisundaram; Wang, Baozhi; Deane, Rashid; Benveniste, Helene; Iliff, Jeffrey J; Nedergaard, Maiken

2013-05-01

Neurodegenerative diseases such as Alzheimer's are associated with the aggregation of endogenous peptides and proteins that contribute to neuronal dysfunction and loss. The glymphatic system, a brain-wide perivascular pathway along which cerebrospinal fluid (CSF) and interstitial fluid (ISF) rapidly exchange, has recently been identified as a key contributor to the clearance of interstitial solutes from the brain, including amyloid β. These findings suggest that measuring changes in glymphatic pathway function may be an important prognostic for evaluating neurodegenerative disease susceptibility or progression. However, no clinically acceptable approach to evaluate glymphatic pathway function in humans has yet been developed. Time-sequenced ex vivo fluorescence imaging of coronal rat and mouse brain slices was performed at 30-180 min following intrathecal infusion of CSF tracer (Texas Red- dextran-3, MW 3 kD; FITC- dextran-500, MW 500 kD) into the cisterna magna or lumbar spine. Tracer influx into different brain regions (cortex, white matter, subcortical structures, and hippocampus) in rat was quantified to map the movement of CSF tracer following infusion along both routes, and to determine whether glymphatic pathway function could be evaluated after lumbar intrathecal infusion. Following lumbar intrathecal infusions, small molecular weight TR-d3 entered the brain along perivascular pathways and exchanged broadly with the brain ISF, consistent with the initial characterization of the glymphatic pathway in mice. Large molecular weight FITC-d500 remained confined to the perivascular spaces. Lumbar intrathecal infusions exhibited a reduced and delayed peak parenchymal fluorescence intensity compared to intracisternal infusions. Lumbar intrathecal contrast delivery is a clinically useful approach that could be used in conjunction with dynamic contrast enhanced MRI nuclear imaging to assess glymphatic pathway function in humans.

Trans fatty acid content in Serbian margarines: Urgent need for legislative changes and consumer information.

Science.gov (United States)

Vučić, Vesna; Arsić, Aleksandra; Petrović, Snježana; Milanović, Sandra; Gurinović, Mirjana; Glibetić, Maria

2015-10-15

This study examined the fatty acid (FA) composition of 13 (7 soft and 6 hard) Serbian margarines. Significantly higher amounts of trans fatty acids (TFA) were found in hard margarines (up to 28.84% of total FA), than in soft ones (0.17-6.89%). Saturated FA (SFA) were present with 22.76-51.17%. Oleic acid ranged from 26.78% to 43.78%. The proportion of polyunsaturated FA (PUFA) was 22.15-49.29% in soft margarines, but only 8.02-15.28% in hard margarines, probably due to the hydrogenisation process. The atherogenic and thrombogenic indexes (AI and TI, respectively) in soft margarines were relatively low (AI 0.23-0.63 and TI 0.44-0.97), but in hard margarines AI and particularly TI were high (1.03-1.67 and 1.96-3.04, respectively). These findings suggest that FA composition of Serbian margarines should be improved by replacing atherogenic TFA and SFA with beneficial ones, in order to avoid adverse effects on health. Therefore legislative changes and consumer information are urgently needed. Copyright © 2015 Elsevier Ltd. All rights reserved.

The ideology of moderated modernism in Serbian music and musicology

Directory of Open Access Journals (Sweden)

Medić Ivana

2007-01-01

Full Text Available The term ′moderated modernism′ has been current for quite some time in Serbian music historiography, but there have been only a few attempts to define it. I shall try to define the term, introduce some of its key concepts and features and demonstrate its applicability. Although moderated modernism was an international phenomenon which had divergent manifestations in various periods before and after the Second World War throughout Europe, my aim is to focus on the period between the decline of Socialist Realism and the ascent of post-modernism (roughly 1950 to 1980 in socialist Serbia, and to discuss the discourses and ideologies surrounding moderated modernism then and there.

Choice of root canal irrigants by Serbian dental practitioners

Directory of Open Access Journals (Sweden)

Tošić Goran

2016-01-01

Full Text Available Background/Aim. Root canal treatment is considered to be the one of the most important procedures in endodontic treatment. To irrigate the root canal it is most common to use sodium hypochlorite (NaOCl, chlorhexodine, ethylenediami-netetraacetic acid (EDTA, local anesthetic solution, while the most used in Serbia is hydrogen peroxide (H2O2. The aim of this survey was to reveal the preferred root canal irrigants used by general dental practitioners in Serbia and to determine the influence of the continuing education program, delivered over the 3-year observation period, on work habits of dental practitioners. This was the first comprehensive survey of this nature carried out in Serbia. Methods. The survey was conducted in two instances, a 4-month observation period each, from November 1, 2009 to March 1, 2010 and from November 1, 2012 to March 1, 2013. Internet Web Page Survey was posted on the official web site of the Serbian Association of Private Dentists. In the first survey, 569 completed questionnaires were subjected to analysis. In the next attempt (3 years later, the survey was launched again and 615 completed questionnaires were analyzed using the same criteria. The statistical analysis was carried out with simple descriptive statistics applying the χ2 test, at a significance level of p < 0.05. Results. The first survey included 569 dental practitioners, while 3 years later the number of them was 615. Analyzing the questionnaires revealed the number of 10 to 30 interventins on the root canal montly. The most commonly used irrigant solution was H2O2 in 2009, while in 2012 it was yet H2O2, but also NaOCl, chlorhexodine, and a little less EDTA. Conclusion. This study shows significant changes in the irrigation protocol applied in Serbian dental community. After 3 years of observation, NaOCl became widely accepted as the irrigant of choice, whereas H2O2 lost its popularity.

Soldiers suicides risk factors in the Serbian Army Forces

Directory of Open Access Journals (Sweden)

Dedić Gordana

2010-01-01

Full Text Available Background/Aim. Analyses of suicide risk factors enable to undertake appropriate preventive measures within the Suicide Prevention Program in Military Environment, which was fully applied in 2003 in the Serbian Army Forces. The aim of our study was to identify the most important suicide risk factors in soldiers within the period from 1998 to 2007. Methods. Analysis of suicide risk factors was carried out on the basis of data obtained by psychological suicide autopsy. The control group was matched with adapted soldiers by socio-demographic factors. A descriptive statistical analysis was used. Comparison of groups of soldiers was done by the t-test and Pearson's χ2-test. Results. A total of 35 soldiers aged 22-49 years (21.76 ± 1.76 years on average committed suicide within the period 1999-2007, the 2/3 within, and 1/3 out of a military compound. More than one half soldiers committed suicide after transferring to a different post. Soldiers who committed suicide had come from uncompleted, dysfunctional families (p < 0.05. In comparison with the adapted soldiers, in premilitary period they had more interpersonal problems with their comrades (p < 0.001 and problems with law (p < 0.05. During military service, alcohol consumption was less presented; they used to have fewer separation problems (p < 0.05 and to be rarely awarded (p < 0.001 in comparison with the adapted soldiers. A soldier who committed suicide was emotionally and socially immature persons. The commonest motives for suicide were: decreased capacity of adaptation to military service, actual psychic disturbance, emotional interruption, fear of environment judgment, actual family problems, but in the one fifth, motive stayed unrecognized. Conclusion. Suicide risk factors in soldiers are primary in their immature personality organization, its relation with family and military environment factors which, in coexistence with actual life accidents, result in suicide as a consequence. A

Memories of Serbian victims under Bulgarian occupation in Leskovački glasnik (1915-1918

Directory of Open Access Journals (Sweden)

Antić Dejan D.

2015-01-01

Full Text Available The Serbian army was forced to retreat towards Metohija and Albania eventually due to the armed aggression and attacks from the north and east in October 1915 by the united forces of the German and Austro-Hungarian units against the Kingdom of Serbia. Together with the army, the monarch, executive and legislative branch, intellectuals and civilians also retreated, not wanting to fall in the hands of the incoming army formations of the Central Powers. Following the retreat of the government and army bodies, the territory of the Kingdom of Serbia found itself under the control of the enemy forces, which started the 3-year period of occupation. The subject of this paper are the texts written by the newspaper called Leskovački glasnik (Leskovac Messenger in the period between World War I and World War II, which dealt with the sufferings of the Serbian civilians in the Bulgarian occupied zone from 1915 to 1918. Special attention is paid to the Leskovački glasnik's reports about marking the anniversary of the Bulgarian terror and killings of Serbs, about opening and consecration of memorials, about the heroic deeds and the tragic destiny of the people in south Serbia.

Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing

DEFF Research Database (Denmark)

Jensen, Vivi Flou Hjorth; Molck, Anne-Marie; Martensson, Martin

2017-01-01

compound in these studies, and a comparator model of persistent exposure by HI infusion from external pumps has recently been developed to support toxicological evaluation of long-acting insulin analogues. However, this model requires single housing of the animals. Developing an insulin-infusion model...... which allows group housing would therefore greatly improve animal welfare. The aim of the present study was to investigate the suitability of implantable infusion pumps for HI infusion in group-housed rats. Group housing of rats implanted with a battery-driven pump proved to be possible. Intravenous...... infusion of HI lowered blood glucose levels persistently for two weeks, providing a comparator model for use in two-week repeated-dose toxicity studies with new long-acting insulin analogues, which allows group housing, and thereby increasing animal welfare compared with an external infusion model....

Adequateness of applying the Zmijewski model on Serbian companies

Directory of Open Access Journals (Sweden)

Pavlović Vladan

2012-12-01

Full Text Available The aim of the paper is to determine the accuracy of the prediction of Zmijewski model in Serbia on the eligible sample. At the same time, the paper identifies model's strengths, weaknesses and limitations of its possible application. Bearing in mind that the economic environment in Serbia is not similar to the United States at the time the model was developed, Zmijewski model is surprisingly accurate in the case of Serbian companies. The accuracy was slightly weaker than the model results in the U.S. in its original form, but much better than the results model gave in the U.S. in the period 1988-1991, and 1992-1999. Model gave also better results in Serbia comparing those in Croatia, even in Croatia model was adjusted.

LEAN MANUFACTURING IN TWO SERBIAN FOOD COMPANIES - CASE STUDIES

Directory of Open Access Journals (Sweden)

Ilija Đekić

2012-06-01

Full Text Available This paper gives an overview of a 9 month experience in implementing lean manufacturing tools in two Serbian food companies. Both companies have certified quality and food safety management systems and are food exporters. One of them is a big producer with more than 1000 employees with a three shift serial production while the other is a small producer with one shift and batch oriented production. Results showed that six tools were chosen by both companies - Total productive maintenance, Poka yoke, batch reduction, layout improvement, standardization of work and visual management. The big company implemented also cellular and flow, Jidoka, quick changeovers and 5S. None of the companies expressed interest at implementing Just-In-Time, Kanban, Self-inspection and Value stream mapping at this stage of the project.

How can the Serbian diaspora contribute much more to the development at home country?

OpenAIRE

Grečić Vladimir

2016-01-01

This article analyzes the existing contribution of the Serbian diaspora to the development at home country, and features of its major effects as a partner in the process of economic development. No doubt, the spiritus movens of the contemporary and future economic and social progress is and will be the economy of ideas and creativity. The key factors of this new economy are education, research and innovation. To achieve competitiveness in an increasingly gl...

Some Challenges of Creating a New Brand of Serbian Tourism: Case Study – The Republic of Užice

Directory of Open Access Journals (Sweden)

Miroslav Ivanović

2009-01-01

Full Text Available Throughout the national history, the southwestern Serbia has been considered as a strong communist center during the National War of Liberation under the authority of Tito, the Communist Party and the ideology of communism holders. This period is presented by the memorial complexes, squares, the Fires of Republic of Užice events, exhibitions in the rebellion museums, busts... These symbols of the past should not be exposed to oblivion, but must be freed of ideological stereotypes and megalomania. The Republic of Užice, as tourist product, is not yet evaluated, nor covered by the range of additional contents that could be a part of the tourist offer in this area. Historical facts and legends create inexhaustible possibility for tourist promotion of the Republic of Užice. This paper presents the possibility of creating a new brand in Serbian tourism and its significance for reviving neglected part of Serbian national history

Strontium-rubidium infusion pump with in-line dosimetry

International Nuclear Information System (INIS)

Barker, S.L.; Loberg, M.D.

1986-01-01

A strontium-rubidium infusion system is described which consists of: (a) means for generating rubidium 82 in a solution which can be infused into a patient; (b) means for infusing the solution into a patient; (c) means for measuring the radioactivity present in the solution as it is infused into the patient; and (d) means for controlling the means for infusing in response to the amount of radioactivity which has been infused into the patient

The U.S. home infusion market.

Science.gov (United States)

Monk-Tutor, M R

1998-10-01

Medicare legislation stimulated the development of home care services but also resulted in fragmentation of service components. In the 1980s, prospective pricing and diagnosis-related groups, and resulting pressures to reduce inpatient length of stay, prompted additional growth of the industry. Even so, in 1995 home care represented only 3% of total national expenditures on health care. The annual growth rate of the home infusion industry dropped from 64% in 1982-86 to 24% in 1986-93. While revenue per patient for home infusion is expected to decrease under managed care, an increasing number of patients will support continued market growth. The home infusion market is highly competitive, with only a few large national providers and many small local providers. In 1996, 29% of acute care hospitals provided or were developing a home care program. Community pharmacists' options in the home infusion area include independent services, partnerships, joint ventures, contracts with hospitals, and franchises. The home infusion market is being integrated into alternative sites, such as ambulatory infusion centers (AICs), as providers attempt to diversify to maintain managed care contracts. AICs provide infusion therapy and nursing to noninstitutionalized, nonhome-bound patients. Untapped sources for future growth of the infusion market include long-term-care facilities. More consistent studies of the home care market are needed. Despite slowed growth in recent years, home care has a strong market in the United States.

Early mechanism of action of arterially infused ethanol: an experimental study on the influence of infusion speed

International Nuclear Information System (INIS)

Han, Joon Koo

1988-01-01

Abdominal aortography and histopathologic examination after absolute ethanol infusion at fast (0.4cc/sec) and slow speed (0.04cc/sec) were performed on 16 rats (2 controls. 7 fast infusion group. 7 slow infusion group). Angiographic and histopathologic findings were correlated and the findings of slow and fast infusion groups were studied. The results are as follows: 1. Histopathologic findings of the fast infusion group revealed wide area of glomerular and tubular collapses, obliteration of the free space between the Bowmann's capsule and glomerulus, sloughing and loss of the endothelium, fresh thrombi attached to the wall, and cleavage of the muscle layer of the arteries. 2. Angiographic findings of the fast infusion group revealed luminal irregularity, early obstruction of the aorta and the renal arteries, and delayed circulation time. 3. Histopathologic findings of the slow infusion group revealed degenerated, coalesced red blood cell packed in the glomeruli, focal areas of severe glomerular and tubular damage on relatively normal background, endothelial and muscular damage of the arteries. 4. Angiographic findings of the slow infusion group revealed focal perfusion defect of the kidney, delayed circulation time, and mild luminal irregularity, but there was no obstruction of the major arteries. 5. In conclusion, author believes that endothelial damage and thrombus formation from the damaged vessel wall, as well as direct cytotoxicity and in situ emboli formation play a significant role in the embolic effect of absolute ethanol.

The Byzantine apocalyptic tradition a fourteenth-century Serbian version of the Apocalypse of Anastasia

Directory of Open Access Journals (Sweden)

Marjanović-Dušanić Smilja

2011-01-01

Full Text Available Early translations of the Apocalypse of Anastasia into Old Church Slavonic appear in several versions incorporated into miscellanies of the zbornik (collection type. These texts belong to various genres of religious prose and are usually assembled in apocryphal collections about journeys to the other world. The earliest known Serbian version of the Apocalypse of Anastasia is the fourteenth-century manuscript dated to about 1380 (MS 29. The present paper gives an analysis of this narrative.

IT Education as an Opportunity for Uprising of Serbian Economy

Directory of Open Access Journals (Sweden)

Božidar Radenković

2014-07-01

Full Text Available The analysis of IT market in Serbia indicates an increase in exports of IT services. Consequently, the need for experts with competitive skills in modern information and communication technologies rises. International priorities related to the application of IT in business and science until the year 2020 include: e-education, cloud computing, mobile technologies, internet of things, ubiquitous and pervasive computing, social media, virtual reality, and big data. Designing environment for providing IT services in these fields can be an opportunity for the development of Serbian economy, because it does not require high infrastructural investments, only investments in education. This paper gives a proposal for leveraging higher education and lifelong learning in Serbia, with respect to the demands of the IT market.

21 CFR 880.5725 - Infusion pump.

Science.gov (United States)

2010-04-01

... Infusion pump. (a) Identification. An infusion pump is a device used in a health care facility to pump fluids into a patient in a controlled manner. The device may use a piston pump, a roller pump, or a... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Infusion pump. 880.5725 Section 880.5725 Food and...

[Dr. Jovan Andrejević Jols, the first Serbian anatomist life, work and achievement].

Science.gov (United States)

Sakač, Dejan; Sakač, Vladimir; Čabarkapa, Velibor; Bugarski, Vojislava

2011-01-01

Doctor Jovan Andrejević Joles was one of the most educated Serbs of the 19th century, a medical doctor, scientist, journalist and translator. He was born in 1883 in Novi Sad. Even as a student of medicine he was active in scientific work, which resulted in a paper entiteled "The fine structure of the liver," later published in one of the most eminent medical journals in Europe. He completed the study of medicine in Vienna. He did not accept the position at the Medical Faculty in Vienna, and returned to Novi Sad, where he quickly gained an excellent reputation as a physician. He participated in the founding of the Serbian National Theatre in 1861, he was also one of the most active contributors of Matica Srpska, wrote many articles, critics and reviews, and was also regarded as the founder of aesthetic romanticism in Serbs. With Laza Kostić, he was the first among the Serbs to translate Shakespeare. At that time, when he was only 30 years old, he wrote about a brand-new art - photography. He lived in a harmonious marriage with Jelena - Ilka Bajić, who after Joles' death remarried to a captain of the Serbian army, and after his murder, became famous for the assassination attempt of King Milan Obrenović (recorded in history textbooks as the "Rebellion of Ilka"). Dr. Jovan Andrejevć died prematurely of tuberculosis, at that time an incurable disease, in 1864 in Novi Sad.

The global financial crisis and the behavior of short-term interest rates: International and Serbian aspects

Directory of Open Access Journals (Sweden)

Đukić Đorđe

2009-01-01

Full Text Available Throughout the current global financial crisis the market has continued to fall due to a lack of confidence of those banks that are not yet prepared to lend on the interbank money market. For instance, the negative repercussions of the crisis onto the Serbian financial sector have created a number of issues including a significant increase in lending rates, a difficulty, or impossibility, for the corporate sector to use cheap cross-border loans and a reduction in the supply of foreign exchange on that basis. The inability of the National Bank of Serbia to follow the aggressive reduction of the key interest rate that has been implemented by central banks in developed countries, partly explains the lack of a decline in short-term interest rates by the Serbian banking industry. The first section of the paper focuses on the effects of the financial crisis through the behavior of short-term interest rates in the US and Europe, while the second section gives an estimation of the effects of the global financial crisis on interest rates in the banking industry in Serbia.

Application of productive research tasks in working with gifted students in teaching Serbian language and literature

Directory of Open Access Journals (Sweden)

Stakić Mirjana M.

2015-01-01

Full Text Available In the work we examine the possibility of application of productive research tasks in working with gifted students in teaching Serbian language and literature. Using specific examples of interpretations of literary works we show that productive research assignments encourage students' creative and inventive expression, creativity, imagination and criticality and enable them to develop in accordance with their personality, individual preferences and abilities. In the examples of their use in problem solving, we determine how productive research tasks are conducive to gifted students who need to learn through problem solving and school work and to experience learning as a challenge. They present the basis for independent research, which allows gifted students to express their own creativity and the need to acquire new, challenging knowledge, and represent a powerful motivational tool that teachers can use in order to further develop their talent. Creative application of the productive research tasks in teaching Serbian language and literature is the possibility that the education of gifted students is not treated as elitist question, but to transform teaching process into development of giftedness and talent, where the role of the teacher in the teaching process rises to the role of the mentor.

Great War legacies in Serbian culture

Directory of Open Access Journals (Sweden)

Milojković-Đurić Jelena

2015-01-01

Full Text Available In the aftermath of the Great War, Ivo Andrić published a number of poems, essays and short stories describing the hard-won victorious outcome as transient to the dire reality of the inordinate loss of human lives and suffering. Yet, personal experiences, although perceived as ephemeral, helped to define the historical discourse capturing man’s resolve to persist in his chosen mission. Over time, Serbian literature and fine arts sustained an unfinished dialogue of the past and the present, merging the individual voices with the collective voices to construct the national narrative. The young writer Miloš Crnjanski observed the sights of destruction and despair that seemed to pale in new literary works pertaining to the war. His novel A Diary about Čarnojević was closely related to his own perilous wartime journey as a conscript in the Austrian army. The vastness of Pannonian plains and Galician woods must have invoked a comparison of sorts with another historic chapter recorded in the collective consciousness of his nation: the Great Migration of Serbs led by Patriarch Arsenije III Čarnojević (Crnojević in 1690. The very title of the novel contained a powerful reference to the migration, and its illustrious historic leader which has not been discussed or explored before.

[A Case of HPN, In Which QOL Improvement Was Achieved by Combining Continuous Infusion with Once-Weekly Intermittent Infusion - Contribution of Pharmacists to Health Promotion among Home Patients Receiving Infusion Therapy].

Science.gov (United States)

Takeda, Namihiro; Hamana, Tomoko; Oka, Toyoka; Hirohara, Masayoshi; Kushida, Kazuki

2016-12-01

Patients receiving parenteral nutrition at home have the following two options: 24-h continuous or intermittent infusion. To date, for patients with impaired glucose tolerance and/or other metabolic disorders or for those with decreased cardiac/ pulmonary/renal function, it is desirable to opt for continuous infusion to minimize the variance in the body's metabolic rate as much as possible. Furthermore, it should be noted that continuous infusion evokes a stronger feeling among patients of being constrained because it restricts their everyday activities. This case witnesses collaborations among the patient's doctor, dispensary's pharmacy, and patient's family. Because ofthe use ofintermittent infusion more or less once per week in addition to continuous infusion, significant improvement in quality of life was achieved, and the patient was able to enjoy taking a short trip. To assist a home patient receiving infusion therapy, it is essential that the pharmacist be equipped with skills to manage risks associated with infusion therapy and have knowledge about insurance to cover incidents concerning infusion fluids or medical materials. It will certainly depend on the degree ofindependence ofpatients and the level ofcare their families can provide; however, should we manage to use a similar medical procedure in at least a few cases in the future, we may be able to contribute to "joie de vivre" in home patients receiving infusion therapy.

Psychometric Properties of the Serbian Version of the Maslach Burnout Inventory-Human Services Survey: A Validation Study among Anesthesiologists from Belgrade Teaching Hospitals.

Science.gov (United States)

Matejić, Bojana; Milenović, Miodrag; Kisić Tepavčević, Darija; Simić, Dušica; Pekmezović, Tatjana; Worley, Jody A

2015-01-01

We report findings from a validation study of the translated and culturally adapted Serbian version of Maslach Burnout Inventory-Human Services Survey (MBI-HSS), for a sample of anesthesiologists working in the tertiary healthcare. The results showed the sufficient overall reliability (Cronbach's α = 0.72) of the scores (items 1-22). The results of Bartlett's test of sphericity (χ(2) = 1983.75, df = 231, p Kaiser-Meyer-Olkin measure of sampling adequacy (0.866) provided solid justification for factor analysis. In order to increase sensitivity of this questionnaire, we performed unfitted factor analysis model (eigenvalue greater than 1) which enabled us to extract the most suitable factor structure for our study instrument. The exploratory factor analysis model revealed five factors with eigenvalues greater than 1.0, explaining 62.0% of cumulative variance. Velicer's MAP test has supported five-factor model with the smallest average squared correlation of 0,184. This study indicated that Serbian version of the MBI-HSS is a reliable and valid instrument to measure burnout among a population of anesthesiologists. Results confirmed strong psychometric characteristics of the study instrument, with recommendations for interpretation of two new factors that may be unique to the Serbian version of the MBI-HSS.

Psychometric Properties of the Serbian Version of the Maslach Burnout Inventory-Human Services Survey: A Validation Study among Anesthesiologists from Belgrade Teaching Hospitals

Directory of Open Access Journals (Sweden)

Bojana Matejić

2015-01-01

Full Text Available We report findings from a validation study of the translated and culturally adapted Serbian version of Maslach Burnout Inventory-Human Services Survey (MBI-HSS, for a sample of anesthesiologists working in the tertiary healthcare. The results showed the sufficient overall reliability (Cronbach’s α = 0.72 of the scores (items 1–22. The results of Bartlett’s test of sphericity (χ2 = 1983.75, df = 231, p<0.001 and Kaiser-Meyer-Olkin measure of sampling adequacy (0.866 provided solid justification for factor analysis. In order to increase sensitivity of this questionnaire, we performed unfitted factor analysis model (eigenvalue greater than 1 which enabled us to extract the most suitable factor structure for our study instrument. The exploratory factor analysis model revealed five factors with eigenvalues greater than 1.0, explaining 62.0% of cumulative variance. Velicer’s MAP test has supported five-factor model with the smallest average squared correlation of 0,184. This study indicated that Serbian version of the MBI-HSS is a reliable and valid instrument to measure burnout among a population of anesthesiologists. Results confirmed strong psychometric characteristics of the study instrument, with recommendations for interpretation of two new factors that may be unique to the Serbian version of the MBI-HSS.

Quartz OSL dating of late quaternary Chinese and Serbian loess: A cross Eurasian comparison of dust mass accumulation rates

DEFF Research Database (Denmark)

Peric, Zoran; Adolphi, Emma Lagerbäck; Stevens, Thomas

2018-01-01

on multi-millennial timescales, with no detailed examination of dust MAR at the two ends of the Eurasian loess belt on shorter, sub-orbital scales. Here we present a detailed quartz optically stimulated luminescence (OSL) chronology from the Serbian Titel Loess Plateau (Veliki Surduk loess core...

Infusion-related reactions to infliximab in patients with rheumatoid arthritis in a clinical practice setting: relationship to dose, antihistamine pretreatment, and infusion number.

Science.gov (United States)

Wasserman, Michael J; Weber, Deborah A; Guthrie, Judith A; Bykerk, Vivian P; Lee, Peter; Keystone, Edward C

2004-10-01

We describe infusion-related reactions to infliximab (during infusion or within 1 hour postinfusion) in patients with active rheumatoid arthritis (RA) treated in a quaternary care center. We followed 113 patients for a mean of 60.6 +/- 28.9 weeks, obtaining 10.5 +/- 4.9 infusions per patient. We observed 1183 infusions resulting in 104 infusion reactions (8.8%). All reactions resolved within several hours following cessation of the infusion and none was serious enough to warrant hospitalization. Reactions included allergic reactions (pruritus, urticaria) in 4.2% of infusions, cardiopulmonary (hypotension, hypertension, tachycardia) in 3.0%, and miscellaneous reactions (headache, nausea, vomiting) in 2.0%. Reactions occurred in 8.0% of 3 mg/kg infusions and in 10.3% of 5 mg/kg infusions. Reactions occurred in 13.2% of infusions that involved antihistamine pretreatment compared to only 7.5% of infusions that involved no pretreatment. At both infliximab doses, there was a similar frequency of infusion reactions in patients pretreated due to a previous infusion (12.6%) compared to those pretreated strictly based on infusion number (14.7%). A number of the reactions involving antihistamine pretreatment may be explained by known side effects of diphenhydramine, including headache, dizziness, nausea, and palpitations. Infusion-related reactions to infliximab were infrequent, rarely severe, and easily manageable. The frequency of reactions was equivalent in patients treated with 3 mg/kg compared to 5 mg/kg. Reactions were significantly more frequent in infusions where patients were pretreated with the antihistamine diphenhydramine, compared to those not involving pretreatment.

Extended infusion versus intermittent infusion of imipenem in the treatment of ventilator-associated pneumonia.

Science.gov (United States)

Ibrahim, Mohamed M; Tammam, Tarek Fouad; Ebaed, Mohy El Deen; Sarhan, Hatem A; Gad, Gamal F; Hussein, Amal K

2017-01-01

Mechanical ventilation support can be the main source of ventilator-associated pneumonia (VAP). VAP is a serious infection that may be associated with dangerous gram-negative bacteria mainly, and it leads to an increase in the mortality in the intensive care unit (ICU). Imipenem is one of the strongest antibiotics now available for treating VAP which is associated with gram-negative and gram-positive bacteria, and it belongs to beta-lactam antibiotic group (carbapenem). This study tried to investigate the efficacy of imipenem against VAP when it was infused within 180 min versus the efficacy when it was infused within 30-60 min. This study was conducted in main ICU in general hospital which consists of surgical and medical beds within 2 years. One hundred and eighty-seven patients were enrolled on it. This study is a retrospective cohort which was conducted within 2 years. The efficacy of imipenem which was administered by intermittent infusion (30-60 min) within first year was compared with the efficacy of imipenem which was administered by extended infusion (180 min) within second year in the field of VAP curing and cost reduction. All data were collected retrospectively from patient medical files and were statistically analyzed by SPSS version 20. The study was designed to measure clinical and cost reduction outcomes, mortality and hospital stay. The results indicated that there is a significant decrease in mortality, number of recurrent infection, and ICU stay length, and the number of mechanical ventilator days was associated with extended imipenem infusion during the second year of the study. The use of imipenem with extended infusion over 3 hours enhances its clinical outcomes in the treatment of VAP.

Understanding Infusion Pumps.

Science.gov (United States)

Mandel, Jeff E

2018-04-01

Infusion systems are complicated electromechanical systems that are used to deliver anesthetic drugs with moderate precision. Four types of systems are described-gravity feed, in-line piston, peristaltic, and syringe. These systems are subject to a number of failure modes-occlusion, disconnection, siphoning, infiltration, and air bubbles. The relative advantages of the various systems and some of the monitoring capabilities are discussed. A brief example of the use of an infusion system during anesthetic induction is presented. With understanding of the functioning of these systems, users may develop greater comfort.

Theoretical points of view on the notion of cause (consideration of contracts in the Serbian doctrine of civil law till the adoption of the law on obligations

Directory of Open Access Journals (Sweden)

Dudaš Atila

2011-01-01

Full Text Available In this paper the author analyzes the different points of view on the notion of cause (consideration in contract in the Serbian doctrine of civil law as until the adoption of the Law on Obligations in 1978. Having in mind that the Law, adhering to the normative solutions of the French Civil Code, explicitly regulates the institution of cause of contract, as one of the conditions of formation and validity of contract, its adoption can certainly be considered as an event of a watershed importance in respect of the analysis of various theoretical points of view on the notion of cause of contract in the Serbian literature. The fact that the institution of cause of contract had not been explicitly regulated in Serbian positive law as until the adoption of Law on Obligations had its effect on the evolution of doctrine in this period in two ways. On one hand, the range of differing theoretical points of view was very wide, covered as good as all the relevant streams in the doctrine of cause, from the ones accepting this institution (so-called causalistic theories to the ones denying its legal significance in any sense (so-called anticausalistic theories. By the adoption of the Law on Obligations in 1978 the notion of cause of contract became a legal institution in Serbian positive law that had a profound impact on the evolution of doctrine. On one hand, the cause of contract was not a neglectable legal notion any more, therefore it seems entirely logical that there is as good as no authority since then who has not dedicated to the notion of cause of contract an article or two, or at least a separate part in their textbooks. On the other hand, the determination of the legislator to assign the Serbian legal system to the family of legal systems in which the notion of cause of contract is stipulated as one of conditions of formation and validity of contract, led to the shrinkage of the diapason of various, often conflicting, points of view on cause of

Swelling and infusion of tea in tea bags.

Science.gov (United States)

Yadav, Geeta U; Joshi, Bhushan S; Patwardhan, Ashwin W; Singh, Gurmeet

2017-07-01

The present study deals with swelling and infusion kinetics of tea granules in tea bags. The swelling and infusion kinetics of tea bags differing in tea loading and tea bag shapes were compared with loose tea. Increment in temperature and dipping frequency of tea bag in hot water increased the infusion kinetics of tea bags. Reduction in particle size enhanced the swelling and infusion kinetics of tea in a tea bag. The effects of tea particle size, tea bag dipping rate, loading of tea granules in tea bag and tea bag shapes on infusion kinetics were investigated. Increase in tea loading in tea bags resulted in reduced infusion kinetics. Double chambered tea bag showed the highest swelling (30%) and infusion kinetics (8.30% Gallic acid equivalence) while single chambered tea bags showed the lowest kinetics, amongst the various bags studied. The swelling and infusion kinetics of loose tea was always faster and higher than that of tea bags. It was found that overall effect of percentage filling of tea granules and height of tea bed in a tea bag affects tea infusion kinetics the most. Weibull model was found to be in good agreement with the swelling data.

Factors driving behavioural intentions: Study of Serbian mobile operator customers

Directory of Open Access Journals (Sweden)

Senić Vladimir

2016-01-01

Full Text Available The concept of perceived value is increasingly becoming a subject of interest for authors and researchers in the field of services marketing. Perceived value represents a multi-dimensional concept that consists of a number of components. In the conducted study, four key components were analyzed: emotional value, social value, functional value and monetary value. The objective of the study was to determine the impact of four identified components of value on customer satisfaction, as well as to test impact of customer satisfaction, corporate social responsibility and corporate reputation on behavioural intentions among Serbian mobile operator customers. Research originates from the assumption that to establish long-term relationships with customers, apart from generating customer satisfaction, issues like customer perception of corporate reputation and corporate responsibility are also of great significance.

Infusion's greenfield subsidiary in Poland

NARCIS (Netherlands)

Williams, C.; van Eerde, W.; The, D.

2012-01-01

The president of Infusion Development Corporation was reviewing the progress of the new subsidiary the company had set up 15 months earlier in Krakow, Poland. The purpose of the subsidiary was to work with other Infusion offices around the world to provide innovative software development services to

Economic analysis of pre-emptive right in the Serbian Law on property restitution and compensation

OpenAIRE

Baturan Luka O.

2015-01-01

This paper is application of cost-benefit analysis on a pre-emptive rights, which is established by the Serbian Law on Property Restitution and Compensation. The basic hypothesis is that this law institute disturbs efficiency of resource allocation, and decreases social welfare. There are a few better and more efficient institutes which can be used for gaining of goods in public ownership. To prove this hypothesis, we used neo-institutional economy method and normative method. In the first pa...

BALLET FOR CHILDREN AT THE SERBIAN NATIONAL THEATRE IN NOVI SAD (1972-2017

Directory of Open Access Journals (Sweden)

Svenka Savić

2018-02-01

Full Text Available Ballets for children have been recognized as a unique genre of the dance art. From the point of children ballet production of the Yugoslav ballet assembly very little was documented, and this particularly referred to the Serbian production. Children‘s ballets aim to provide an experience for young people, to educate on dance art and to attract, engage and sustain children as an audience for major ballet houses. They challenge a whole range of difficultes and problems that have to be solved by the choreographers and dancers. For example, the first major challenge in taking children to the ballet is that the story is told entirely through dance, and many children find this aspect of the ballet difficult to appreciate. The author examined the representations of the ballet body and analyzed how this and some other difficulties have been solved in children‘s ballet production of the Serbian National Theatre Ballet (SNP in Novi Sad during the long period of forty five years, from the first performances in 1972 up to now, namely to 2017. In addition, the author has made an inventory by listing repertoir, choreografies, and stories. She was tracking the number of performances for each production and the number of audience to conclude on the impact of the children‘s ballet. The implication of the paper is that the possibile solutions referred to in the paper could be seen as a suggestion for the future opportunities of the production, particularly in the case of the future premieres.

Pharmacokinetics and toxicology of continuously infused nitroimidazoles

International Nuclear Information System (INIS)

Eifel, P.J.; Brown, J.M.

1984-01-01

The pharmacokinetics and toxicology of misonidazole (MISO) and SR-2508 given by continuous intraperitoneal infusion were studied in female C 3 H mice. The survival (time to death) of animals receiving continuous infusions of SR-2508 and MISO was compared and related to plasma concentration, rate of infusion and total amount of drug delivered. Brain and plasma concentrations were determined by HPLC. For SR-2508, plasma concentration was directly proportional to the infusion rate. However, as the infusion rate of MISO was doubled, the plasma concentration of MISO increased approximately 6-fold, reflecting a substantial increase in the apparent half-life. The brain/plasma concentration ratio in animals infused for up to 6 days with SR-2508 remained constant, at approximately 0.09. At plasma concentrations of 0.08-1.5 mM, animals receiving SR-2508 survived approximately 3 times as long as animals exposed to a comparable plasma concentration of MISO. Even at the lowest infusion rates employed in this study, the survival of mice receiving SR-2508 was much shorter than would have been predicted if the toxicity of these two drugs were solely related to the integral brain exposure. The low brain/plasma concentration ratio of SR-2508 was maintained throughout long continuous exposures

Jasenovac – A Past that Does Not Pass : The Presence of Jasenovac in Croatian and Serbian Collective Memory of Conflict

NARCIS (Netherlands)

Odak, S.; Benčić, A.

2016-01-01

In this article the authors discuss the role of Jasenovac Concentration Camp in Croatian and Serbian political and social spheres. Connecting the historical data with the analysis of the recent mutual accusations of genocide between the Republic of Croatia and the Republic of Serbia before the

MONITORING TETESAN INFUS BERBASIS MIKROKONTROLER ATMEGA16

Directory of Open Access Journals (Sweden)

Ardiyanto Iqbal Nugroho

2015-09-01

Penelitian ini menghasilkan suatu alat monitoring tetesan infus yang dapat memberikan informasi mengenai laju kecepatan tetesan dan kondisi cairan pada infus. Sistem yang secara realtime dimonitoring oleh perawat ini dapat mengurangi permasalahan yang timbul karena kelalaian petugas. Sehingga perawat tidak secara manual dalam mengatur kecepatan tetesan infus dan meningkatkan pelayanan kepada pasien.

Neglecting the Maxim of Manner: How Readers Understand New Anglicisms Used in the Serbian Print Media

Directory of Open Access Journals (Sweden)

Olga Panić-Kavgić

2017-06-01

Full Text Available The paper deals with the reception of new anglicisms by native speakers of Serbian, from semantic and pragmatic viewpoints, through theoretical and empirical observations. The main goal of the paper is to demonstrate to what extent and in what ways speakers understand anglicisms which they regularly encounter in Serbian daily newspapers and weekly magazines. It is through Grice's Cooperative Principle that the relationship between the journalist and the reader is examined and described. The conclusions are based on an analysis of the results of a large-scale research project conducted on a representative sample of native speakers who constitute the target readership of the selected newspapers and magazines. The research tool – an extensive written questionnaire – was created on the basis of a large corpus of anglicisms extracted from non-specialist daily and weekly press. The results of the analysis corroborate the initial hypothesis that there are varying degrees of noise in the communication channel between the journalist and reader, and that the journalist does not adhere to the Cooperative Principle. The way in which one of its maxims is regularly disregarded cannot fit into the existing classification and displays characteristics of a new category here termed ‘neglecting the maxim of manner’.

Determination of 24-hour insulin infusion pattern by an artificial endocrine pancreas for intravenous insulin infusion with a miniature pump

DEFF Research Database (Denmark)

Kølendorf, K; Christiansen, J S; Bojsen, J

1981-01-01

UNLABELLED: Intravenous insulin infusion with a glucose controlled insulin infusion system (GCIIS) is known to restore glucose homeostasis. A simpler approach to improve blood glucose regulation is preprogrammed intravenous insulin infusion with portable pumps without sensor-mediated feedback. We...... report a study designed to evaluate whether the preprogrammed insulin infusion pattern to be used in the miniature insulin infusion pump (MIIP) could be optimized by concomitant employment of the GCIIS for blood glucose control. Six juvenile-onset insulin-dependent diabetics (mean age 31 yrs) were...... studied. Mean blood glucose (MBG) was 6.2 mmol/l +/- 0.5 (SD) during glucose controlled infusion and 5.3 +/- 0.6 during the combined MIIP + GCIIS-day. The insulin requirements calculated from the s.c. regimen (56 U +/- 10 SD) were identical to the GCIIS-measured (51 U +/- 14) and to the amounts delivered...

An anthropometric study of Serbian metal industry workers.

Science.gov (United States)

Omić, S; Brkić, V K Spasojevic; Golubović, T A; Brkić, A D; Klarin, M M

2017-01-01

There are recent studies using new industrial workers' anthropometric data in different countries, but for Serbia such data are not available. This study is the first anthropometric study of Serbian metal industry workers in the country, whose labor force is increasingly employed both on local and international markets. The metal industry is one of Serbia's most important economic sectors. To this end, we collected the basic static anthropometric dimensions of 122 industrial workers and used principal components analysis (PCA) to obtain multivariate anthropometric models. To confirm the results, the dimensions of an additional 50 workers were collected. The PCA methodology was also compared with the percentile method. Comparing both data samples, we found that 96% of the participants are within the tolerance ellipsoid. According to this study, multivariate modeling covers a larger extent of the intended population proportion compared to percentiles. The results of this research are useful for the designers of metal industry workstations. This information can be used in dimensioning the workplace, thus increasing job satisfaction, reducing the risk of injuries and fatalities, and consequently increasing productivity and safety.

The stages of modernism in Serbian music

Directory of Open Access Journals (Sweden)

Milin Melita

2006-01-01

Full Text Available In order to consider this topic, it was first necessary to discuss certain problems of terminology and periodisation relating to musical modernism in general. It is already familiar the extent to which the terms "new music", "modernist", "contemporary" and "avant-garde" music have been used interchangeably, as synonyms. For this reason, it was first important to outline the period of musical modernism as almost generally accepted, which is regarded as an epoch comprising three different periods: (I period of early modernism (1890–1918, announced by a break with later romanticism and a turn towards French Impressionism, Austro-German Expressionism and Russian "folkloric Expressionism"; (II period of "classical modernism"(1919–1945 that witnessed a diffusion of neo-classicism and serialism; (III period of "high modernism" (1946–1972 characterized by highly experimental compositional techniques such as integral serialism and aleatoricism. In relation to this, avant-garde movements are seen as radically innovative and subversive tendencies within this modernist epoch, and while certain postmodernist ideas can be recognized as early as the 1950s, postmodernism as a movement hadn’t gained its full potency until the 1970s. Since then, it has assumed different forms of existence as well as having assimilated a continued form of ‘modernist project’. The second part of the article proposes a periodisation of Serbian musical modernism, which is divided into four stages. The first stage (1908–1945 was a period where elements of Impressionism and German expressionism were creatively introduced into the works of several leading composers (Petar Konjović, Stevan Hristić, Miloje Milojević, Josip Slavenski, Marko Tajčević. The second stage (1929–1945 was marked by a group of composers who studied in Prague and assimilated certain progressive compositional techniques such as free tonality, atonality dodecaphony, microtonality and athematicism

The influence of perceived discrimination, sense of control, self-esteem and multiple discrepancies on the mental health and subjective well-being in Serbian immigrants in Canada

Directory of Open Access Journals (Sweden)

Vukojević Vesna

2016-01-01

Full Text Available The study focuses on the mental health and subjective well-being (SWB of Serbian immigrants of the first generation in Canada. We wanted to examine if perceived discrimination, sense of control, self-esteem and perceived multiple discrepancy affect their mental health and SWB. Our results indicate that self-esteem and sense of control have a positive effect on mental health and all aspects of the SWB, while the perceived discrimination and perceived multiple discrepancy negatively affect SWB and mental health. Self-esteem was the most salient predictor of mental health, while the perceived multiple discrepancy was the most salient predictor of life satisfaction of Serbian immigrants.

Analysis of Y chromosome microdeletions and CFTR gene mutations as genetic markers of infertility in Serbian men

Directory of Open Access Journals (Sweden)

Dinić Jelena

2007-01-01

Full Text Available Background/Aim. Impaired fertility of a male partner is the main cause of infertility in up to one half of all infertile couples. At the genetic level, male infertility can be caused by chromosome aberrations or gene mutations. The presence and types of Y chromosome microdeletions and cystic fybrosis transmembrane conductance regulator (CFTR gene mutations as genetic cause of male infertility was tested in Serbian men. The aim of this study was to analyze CFTR gene mutations and Y chromosome microdelations as potential causes of male infertility in Serbian patients, as well as to test the hypothesis that CFTR mutations in infertile men are predominantly located in the several last exons of the gene. Methods. This study has encompassed 33 men with oligo- or azoospermia. The screening for Y chromosome microdeletions in the azoospermia factor (AZF region was performed by multiplex PCR analysis. The screening of the CFTR gene was performed by denaturing gradient gel electrophoresis (DGGE method. Results. Deletions on Y chromosome were detected in four patients, predominantly in AZFc region (four of total six deletions. Mutations in the CFTR gene were detected on eight out of 66 analyzed chromosomes of infertile men. The most common mutation was F508del (six of total eight mutations. Conclusion. This study confirmed that both Y chromosome microdeletions and CFTR gene mutations played important role in etiology of male infertility in Serbian infertile men. Genetic testing for Y chromosome microdeletions and CFTR gene mutations has been introduced in routine diagnostics and offered to couples undergoing assisted reproduction techniques. Considering that both the type of Y chromosome microdeletion and the type of CFTR mutation have a prognostic value, it is recommended that AZF and CFTR genotyping should not only be performed in patients with reduced sperm quality before undergoing assisted reproduction, but also for the purpose of preimplantation and

Phase-contrast cerebrospinal fluid flow magnetic resonance imaging in qualitative evaluation of patency of CSF flow pathways prior to infusion of chemotherapeutic and other agents into the fourth ventricle.

Science.gov (United States)

Patel, Rajan P; Sitton, Clark W; Ketonen, Leena M; Hou, Ping; Johnson, Jason M; Romo, Seferino; Fletcher, Stephen; Shah, Manish N; Kerr, Marcia; Zaky, Wafik; Rytting, Michael E; Khatua, Soumen; Sandberg, David I

2018-03-01

Nuclear medicine studies have previously been utilized to assess for blockage of cerebrospinal fluid (CSF) flow prior to intraventricular chemotherapy infusions. To assess CSF flow without nuclear medicine studies, we obtained cine phase-contrast MRI sequences that assess CSF flow from the fourth ventricle down to the sacrum. In three clinical trials, 18 patients with recurrent malignant posterior fossa tumors underwent implantation of a ventricular access device (VAD) into the fourth ventricle, either with or without simultaneous tumor resection. Prior to infusing therapeutic agents into the VAD, cine MRI phase-contrast CSF flow sequences of the brain and total spine were performed. Velocity encoding (VENC) of 5 and 10 cm/s was used to confirm CSF flow from the fourth ventricular outlets to the cervical, thoracic, and lumbar spine. Qualitative CSF flow was characterized by neuroradiologists as present or absent. All 18 patients demonstrated CSF flow from the outlets of the fourth ventricle down to the sacrum with no evidence of obstruction. One of these patients, after disease progression, subsequently showed obstruction of CSF flow. No patient required a nuclear medicine study to assess CSF flow prior to initiation of infusions. Fourteen patients have received infusions to date, and none has had neurological toxicity. CSF flow including the fourth ventricle and the total spine can be assessed noninvasively with phase-contrast MRI sequences. Advantages over nuclear medicine studies include avoiding both an invasive procedure and radiation exposure.

Infusing PDA technology into nursing education.

Science.gov (United States)

White, Ann; Allen, Patricia; Goodwin, Linda; Breckinridge, Daya; Dowell, Jeffery; Garvy, Ryan

2005-01-01

Use of the personal digital assistant (PDA) has been infused into the accelerated baccalaureate program at Duke University to help prepare nursing students for professional practice. The authors provide an overview of the use of PDAs in the classroom, laboratory, and clinical setting. Technical aspects of PDA infusion and steps to ensure regulatory compliance are explored. Benefits of PDA use by both faculty and students in the program and challenges met with the infusion of this technology are also described.

Cult of mother Jugović in Serbian epic poetry

Directory of Open Access Journals (Sweden)

Baćović Vukašin K.

2010-01-01

Full Text Available The poetry about Kosovo is a poetry about the Fenix Bird and torture. Because of its esthetic worthiness it is included in the greatest poetry accomplishments of Serbian people and the human kind in general. The Death of the Mother of Jugović is the poem in which spirit trolds the central position. The nature of this mother is characterized by two most supreme human feelings: patriotism and maternity. The poem accumulates pain reaching enormous power of personal, family and collective misery. Love of the mother of Jugović is always fresh because it rises from the never ending spring of a mother's soul. Only great poets such as: Sofocles in Antigona, Aesylus in Prometheus Bound, Shakespeare in Hamlet, Njegoš in The Mountain Wreath and some particular poets of the Bible created similar poetic branches. The cult of the mother of Jugović needs to be breaded new generations may reach new cognitions and new worlds.

Methodological spot of establishing silt deposit concentration in Serbian rivers

Directory of Open Access Journals (Sweden)

Dragićević Slavoljub

2007-01-01

Full Text Available Recent methodology of sampling and establishing silt deposit concentration in Serbian rivers is associated to numerous deficiencies. Daily concentrations of this type of river deposit on the most of the hydrological gauges were obtained on the base of only one measurement, which takes into consideration the matter of representative ness of those samples. Taking the samples of deposit in one point on the profile is little bit problematic because of dispersion of the obtained results. Very important matter is the question of choice of the sampling location. This analyses of data may lead to serious spots in calculating total carried deposit. From the above mentioned reasons, we decided to take precise measurements of silt deposit concentration as well as to establish methodological spots of measurements. The results of these measurements are analyzed and presented in this paper.

Mortgage development in Serbia, specialty in Serbian Civil Code from 1844. year

Directory of Open Access Journals (Sweden)

Popov Danica

2012-01-01

Full Text Available The history of Serbian mortgage law is not too long. The mortgage law began in first half of XIX century. The first Act about mortgage was The Intabulation Law from 1839. year. Mortgage is a right of lien on an immovable which authorizes the creditor to seek satisfaction of his claim for the value of such immovable before of other creditors that do not have mortgage on it, as well as before creditors who have acquired mortgage on such immovable subsequent on him, irrespective of a contingent change of owner of the encumbered immovable. The mortgage was based on some rules. The mortgage is accessory rights. One of the basic features of a security right is its dependence on the claim. The mortgage creditor is entitled to request satisfaction of the claim from the value of immovable encumbered by mortgage, regardless of whether it is still in possession of the mortgage debitor or it has been convened into ownership of a third party. This The Intabulation Law is changed twice. For the first time in 1842 year, and second time in 1853. year. The lack of both changes was missing the principle of speciality. Principle of speciality marks the fact that a guarantee (security, may secure only a definite claim of one creditor and that the guarantee may exist only on a definite set of objects (assets. On one hand speciality of real security interest forbids securing an indefinite number of claims or an indefinite amount of claim, and, on the other, forbids the prospect of indefinite assets, or all assets of the debitor be subject of to such a security interest. This lack are eliminate in the new Intabulation Law from 1854. year, which was incorporated into Serbian Civil Code from 1844. year. The subject of this article is The Intabulation Law from 1854. year.

The effect of glucagon on infusion cholangiography

International Nuclear Information System (INIS)

Evans, A.F.; Whitehouse, G.H.

1979-01-01

An assessment has been made of the effects of glucagon on biliary tract opacification during intravenous cholangiography. Two series of infusion cholangiograms were obtained at two investigating centres designated A and B. In series A, 41 patients had ioglycamide infusions at a rate of 0.2833 g min -1 over 1 h. In series B, 31 patients had ioglycamide infusions at a rate of 0.3886 g min -1 over 30 min. Radiographs were taken in both series immediately at the end of the infusion, 10 min later and 30 min after the infusion. Two mg of intravenous glucagon was injected into alternate cases in both series A and B immediately after the first radiograph was taken at the completion of the ioglycamide infusion. Two observers in each series then assessed the radiographic opacification of the biliary system without prior knowledge of which patients had received the glucagon. Delineation of the biliary system was considered better in both series in those patients who received glucagon when compared with the controls. Gallbladder opacification was definitely increased in series A in those receiving glucagon, and a similar tendency was shown in series B. The amount of contrast in the upper intestine was increased in series A in the glucagon group, but not in series B. It is concluded that glucagon improves visualisation of the biliary tract, especially the gallbladder at infusion cholangiography. (author)

Gender-Based Content of Educational Materials for the Study of Serbian Language in Lower-Stage Grades of Elementary Education

Science.gov (United States)

Trifunovic, Vesna; Petrovic, Ruzica

2014-01-01

This paper presents the results of analysis of educational materials for the study of Serbian language in lower-stage grades of elementary education (intended for students from 7 through 11 years old) from gender perspective. The first part of the paper presents the process of institutionalization of gender-based education in the Republic of…

Pulsatile versus steady infusions for hepatic artery chemotherapy

International Nuclear Information System (INIS)

Kim, E.E.; Haynie, T.P.; Wright, K.C.; Chaynsangavej, C.; Gianturco, C.; Lamki, L.; Wallace, S.

1984-01-01

Hepatic artery chemotherapy for unresectable liver tumors requires an even distribution of the drugs in the tumor or vascular bed. This cannot be determined angiographically because the drugs are infused at a much lower rate than the contrast media. It is easy, however, to determine the quality of the perfusion by injecting a small volume of Tc-99m MAA in one of the side ports while chemotherapeutic agent is being infused at the same rate. Usually this shows a uniform, satisfactory distribution of isotope. Occasionally, however, some areas fail to receive Tc-99m in spite of what appears to be a good position of the catheter tip. Since ''streaming'' of the infused drugs has been blamed for their uneven distribution, the authors decided to compare the usual steady flow infusions with infusions made pulsatile by the addition of a pulsing device (Gianturco Pump) attached to the infusion tubing. Eighty-three patients were studied with steady as well as pulsatile infusions. In 16 of these patients the perfusion pattern was definitely changed by the pulsatile infusion. In one patient the pulsatile mode resulted in an unwanted gastric perfusion. In 5 patients the distribution was improved in one hepatic lobe and in 10 patients it was improved in both lobes. These results show that hepatic artery perfusions can occasionally be improved by pulsing the infusate. However, pulsing can produce the unwanted perfusion of extra-hepatic areas

Liquid-liquid displacement in slippery liquid-infused membranes (SLIMs)

OpenAIRE

Bazyar, Hanieh; Lv, Pengyu; Wood, Jeffery A.; Porada, Slawomir; Lohse, Detlef; Lammertink, Rob G. H.

2018-01-01

Liquid-infused membranes inspired by slippery liquid-infused porous surfaces (SLIPS) have been recently introduced to membrane technology. The gating mechanism of these membranes is expected to give rise to anti-fouling properties and multi-phase transport capabilities. However, the long-term retention of the infusion liquid has not yet been explored. To address this issue, we investigate the retention of the infusion liquid in slippery liquid-infused membranes (SLIMs) via liquid-liquid displ...

Contractual liability: In European, comparative and Serbian law

Directory of Open Access Journals (Sweden)

Salma Jožef

2011-01-01

Full Text Available Contractual liability is an important topic of the ongoing reform of the effective Serbian Law on Obligations (2007-2009, which aims to harmonize the national legislation in this field with the laws of the European Union. In this paper the author analyzes the evolution of the traditional European civil codes (the German BGB, French Code civil, the Austrian ABGB the Swiss OR and the Hungarian Civil Code, with due attention to the doctrine and jurisprudence, taking into account the proposed reforms of the effective Serbian Law on Obligations concerning issues of contractual liability, such as the legal consequences of nonperformance, misperformance, default, etc. The author is of the opinion that the notion of the breach of contract doesn't cover all the cases in which contractual liability arises, although it embraces nonperformance, misperformance and default. The notion of contractual liability, namely, covers not only the cases of breach of contract, but the infringement of public policy, good morals and mandatory rules, which all lead to the nullity of the contract. In cases of voidable contracts (that is in case of defects of contractual will, such as mistake, deceit and duress it is questionable whether the scope of contractual liability should be extended to mistake, which is a case of nonconscious discrepancy between contractual will and its expression. It is undisputable that contractual liability arises in case of deceit and duress, to the burden of the party acting in bad faith. The rescission of contract entails a separate complex of legal issues, since it may be justified by the other party's breach of the contract. It can also be onesided, two-sided or by a mutual agreement. Furthermore, specific rules apply to rescission of contract due to changed circumstances. In case of termination of a contract by mutual agreement, the parties usually agree on the extent of liability, that is on the extent of indemnification. Contractual

Aspects of Linguistic Politeness in Serbian. A Data-based Comparison with German

Directory of Open Access Journals (Sweden)

Katrin Schlund

2014-12-01

Full Text Available The article investigates forms of address and request behaviour in Serbian as compared to German. It is based on an empirical study with authentic speech data and a survey among na-tive speakers of the two languages. While the corpora of authentic speech data document mainly service encounters and other minimal everyday interactions, the survey aims at reveal-ing the judgements and attitudes of native speakers towards different request strategies. The results point towards the well-known distinction between "solidarity cultures" in the East and "distance cultures" in the West. However, such findings must be treated with caution as other factors seem to influence the range of strategies available in the two languages as well.

Financial analysis for the infusion alliance.

Science.gov (United States)

Perucca, Roxanne

2010-01-01

Providing high-quality, cost-efficient care is a major strategic initiative of every health care organization. Today's health care environment is transparent; very competitive; and focused upon providing exceptional service, safety, and quality. Establishing an infusion alliance facilitates the achievement of organizational strategic initiatives, that is, increases patient throughput, decreases length of stay, prevents the occurrence of infusion-related complications, enhances customer satisfaction, and provides greater cost-efficiency. This article will discuss how to develop a financial analysis that promotes value and enhances the financial outcomes of an infusion alliance.

Assessing and identifying transitional losers and winners in the Serbian society

Directory of Open Access Journals (Sweden)

Trifunović Vesna

2012-01-01

Full Text Available This paper presents ways to assess and evaluate losers and winners in the Serbian transitional society, through several concrete examples. Therefore, the paper is a follow-up of the manuscript published in the previous Bulletin of Institute of ethnography, and fits into the theoretical framework already stated. The main indicator of a variety of assessment regarding losers and winners is found among comments made by visitors of relevant Internet web sites, referring to news about societal problems and issues during the process of post-socialist transformation. These are directly linked with a phenomenon of losing or winning in transition, such as unemployment, poverty, criminal, success, failure, wealth, and power. Hence, news from two internet sites "Blic" i "B92" served as a source, while their visitors ‘commentaries to the particular news served in the analysis. Specific news was used to define a particular problem or issue, and the commentaries were seen as reactions to the news. The commentaries contain readers’ attitudes, assessment of particular issues and discourses overview. These comments were chosen based on whether they refer directly to the problem of losing/winning in transition, and on their diversity regarding assessment of the problem itself. At the same time, posted texts on the mentioned sites were not unbiased, and they can also serve to identify losers and winners of transition. Defining a category of losers or winners in transition is a complex issue of various interpretations and constructions, making thus a discrepancy in attributed meanings among the members of Serbian society. Controversy and contradictions in expressed attitudes about losers and winners, as well as understanding of these categories, could be explained by various aspects and outlooks held. In brief, an existing particular social heteroglossia, assumes many different readings and attitudes regarding the categories, caused by various factors. The

Morphological and hydrological characteristics of the Serbian border zone towards Bulgaria

Directory of Open Access Journals (Sweden)

Đurović Predrag

2013-01-01

Full Text Available Morphological and hydrological analyses of the characteristics of the Serbian border zone towards Bulgaria were performed. The morphological analysis included the mountain (Stara Planina, Tupižnica, Svrljiške Planine, Suva Planina and Vidlič, structural basin (Zaječar, Knjaževac, Svrljig and Bela Palanka and valley (Veliki Timok, Beli Timok, Visočica, Dragovištica parts. Within the hydrological analysis, the areas with the highest and lowest annual amount of precipitation were identified, as well as the hottest and coldest areas. The change of river basins runoff was analysed, as well as the distribution of waters throughout the year in the studied area. The most important elements of the water balance were shown and the hydrological characteristics of the karst terrain were analysed.

A comparison of two nuclear-medical techniques for effective renal plasma flow determination in rabbits: Radiation controlled infusion-pump and whole-body measurement according to Oberhausen

International Nuclear Information System (INIS)

Mayer-Wehrstein, R.

1981-01-01

Two nuclear techniques were investigated for determination of the effective renal plasma flow with J-131-Hippuran in rabbits: whole-body measurement according to Oberhausen and clearance determination with a radiation controlled feed back infusion pump. In the first method the clearance determination follows after a single injection of the testing substance in the decreasing phase of the blood level, in the second method a constant blood level of the testing substance is maintained. A technique was developed for the determination of the blood-tissue ratio by considering the values determined by the constant blood level. This way the exact clearance values were computet for the decreasing plasma level. Nineteen clearance determinations were performed in rabbits altogether. (orig.) [de

Network externalities in telecommunication industry: An analysis of Serbian market

Directory of Open Access Journals (Sweden)

Trifunović Dejan

2016-01-01

Full Text Available This paper deals with network competition and provides empirical analysis of market concentration, network and call externalities, access pricing, price discrimination and switching costs in Serbian mobile phone telecommunications market. It is shown that network externalities governed the expansion of this market until 2008. Upon entry of VIP incumbents didn't engage in predatory behaviour towards entrant aiming to benefit from locked- in users. The policy of mobile phone number portability reduced on-net prices and substantially increased consumer's surplus. In contrast to some previous research, this policy was pro-competitive in Serbia. We have also determined that users of the network with the largest market share benefit the most from call externalities. Finally, one network does not price discriminate between outgoing and incoming roaming calls, which implies that users of this network have higher level pecuniary externalities in roaming compared to users of price discriminating networks.

Infusion Antihypoxants in Children with Critical Conditions

Directory of Open Access Journals (Sweden)

Yu. S. Aleksandrovich

2014-01-01

Full Text Available Hypoxia and mitochondrial damage are a key component of the pathogenesis and tanatogenesis of a critical condition, suggesting the need for its prevention and maximally rapid elimination. Objective: to analyze the efficacy and safety of infusion antihypoxants used in critically ill children from the results of researches. Materials and methods. Available investigations dealing with infusion therapy in children and papers on the use of infusion antihypoxants in adults in 2005 to 2013 were sought in the medical databases PubMed and Cochrane Library with their free availability and analyzed. Results. The analysis included 70 trials. The pathophysiology and pathobiochemistry of hypoxia in critically ill children are given; the current principles of its correction by infusion therapy are considered in detail. Particular emphasis is placed on trials evaluating the efficacy and safety of succinic acid solutions in children. Main indications for and contraindications to their use are demonstrated. Conclusion. The use of Krebs cycle substrate-based infusion antihypoxants (malate, succinate is an effective and promising procedure for the intensive therapy and correction of hypoxia in both adults and children with critical conditions. Considering the fact that papers on the use of infusion antihypoxants in children are scanty, there is a need for further investigations. 

Work related characteristics, work-home and home-work interference and burnout among primary healthcare physicians: a gender perspective in a Serbian context.

Science.gov (United States)

Putnik, Katarina; Houkes, Inge

2011-09-23

Little information exists on work and stress related health of medical doctors in non-EU countries. Filling this knowledge gap is needed to uncover the needs of this target population and to provide information on comparability of health related phenomena such as burnout across countries. This study examined work related characteristics, work-home and home-work interference and burnout among Serbian primary healthcare physicians (PHPs) and compared burnout levels with other medical doctors in EU countries. Data were collected via surveys which contained Maslach Burnout Inventory and other validated instruments measuring work and home related characteristics. The sample consisted of 373 PHPs working in 12 primary healthcare centres. Data were analysed using t-tests and Chi square tests. No gender differences were detected on mean scores of variables among Serbian physicians, who experience high levels of personal accomplishment, workload, job control and social support, medium to high levels of emotional exhaustion, medium levels of depersonalisation and work-home interference, and low levels of home-work interference. There were more women than men who experienced low job control and high depersonalisation. Serbian physicians experienced significantly higher emotional exhaustion and lower depersonalisation than physicians in some other European countries. To diminish excessive workload, the number of physicians working in primary healthcare centres in Serbia should be increased. Considering that differences between countries were detected on all burnout subcomponents, work-related interventions for employees should be country specific. The role of gender needs to be closely examined in future studies as well.

Work related characteristics, work-home and home-work interference and burnout among primary healthcare physicians: A gender perspective in a Serbian context

Directory of Open Access Journals (Sweden)

Houkes Inge

2011-09-01

Full Text Available Abstract Background Little information exists on work and stress related health of medical doctors in non-EU countries. Filling this knowledge gap is needed to uncover the needs of this target population and to provide information on comparability of health related phenomena such as burnout across countries. This study examined work related characteristics, work-home and home-work interference and burnout among Serbian primary healthcare physicians (PHPs and compared burnout levels with other medical doctors in EU countries. Methods Data were collected via surveys which contained Maslach Burnout Inventory and other validated instruments measuring work and home related characteristics. The sample consisted of 373 PHPs working in 12 primary healthcare centres. Data were analysed using t-tests and Chi square tests. Results No gender differences were detected on mean scores of variables among Serbian physicians, who experience high levels of personal accomplishment, workload, job control and social support, medium to high levels of emotional exhaustion, medium levels of depersonalisation and work-home interference, and low levels of home-work interference. There were more women than men who experienced low job control and high depersonalisation. Serbian physicians experienced significantly higher emotional exhaustion and lower depersonalisation than physicians in some other European countries. Conclusions To diminish excessive workload, the number of physicians working in primary healthcare centres in Serbia should be increased. Considering that differences between countries were detected on all burnout subcomponents, work-related interventions for employees should be country specific. The role of gender needs to be closely examined in future studies as well.

Bureaucratic behavior: A review of the theory and its application to Serbian public administration

Directory of Open Access Journals (Sweden)

Žarković-Rakić Jelena

2007-01-01

Full Text Available A professional and competent public administration is necessary for successful transition from a socialist, centrally planned economy to a functioning market democracy. The difficulty lies in building an organized and effective civil service sector. This paper gives a brief overview of formal bureaucratic reasoning, beginning with Niskanen’s theory, followed by the principal-agent model. The "Weberian state hypothesis", which provides an alternative view of bureaucracies in less developed countries, is subsequently explored. Finally, the currant state of Serbian public administration is described, along with a discussion of challenges to be addressed in the future.

Proceedings of the VI Serbian-Bulgarian Astronomical Conference, May 7 - 11 2008, Belgrade, Serbia

Science.gov (United States)

Dimitrijević, M. S.; Tsvetkov, M.; Popović, L. C.; Golev, V.

2009-07-01

The Sixth Serbian-Bulgarian Astronomical Conference was organized by Belgrade Astronomical Observatory, and held in Belgrade, in the building of Mathematical Faculty in Jagiceva Street, from 75th to 11th May 2008. Co-organizers were Mathematical Faculty, Astronomical Society "Rudjer Boskovic", Institute of Astronomy of the Bulgarian Academy of Sciences (BAS), Space Research Institute of BAS and Department of Astronomy of the University of Sofia. Co-chairmen of the Scientific Organizing Committee were Milan Dimitrijevic and Milcho Tsvetkov and Co-vice chairmen Luka C. Popovic and Valeri Golev. Chair of the Local Organizing Committee was Andjelka Kovacevic. The conference [was] attended by 58 participants. From Serbia were 36, from Belgrade Astronomical Observatory, Mathematical Faculty, Faculty of Sciences from Nis, Institute of Physics from Zemum, High School for pedagogues of occupational studies from Aleksinac, Faculty of Sciences from Kragujevac, Mathematical Institute of Serbian Academy of Sciences and Arts, Astronomical Society "Rudjer Boskovic" and Astronomical Society "Magellanic Cloud." From Bulgaria were present 17 colleagues: Svetlana Boeva, Ana Borisova, Momchil Dechev, Peter Duchlev, Lostadinka Koleva, Georgi Petrov, Vasil Popov, Konstatin Stavrev, Katya Ysvetkova and Milcho Tsvetkov from Institute of Astronomy of BAS, Rumen Bogdanovski and Krasmimira Ianova from Space Research Institute of BAS, Georgi R. Ivanov, Georgi Petrov and Grigor Nikolov from Department of Astronomy, Sofia University "St Kliment Ohridski,", Yavor Chapanov from Central Laboratory for Geodesy of BAS and Petya Pavlova from Technical University of Sofia, Branch Plovdiv. Besides participants from Serbia and Bulgaria the Conference [was] attended [by] Vlado Milicevic from Canada, Jan Vondrak from Czech Republic, Aytap Sezer from Turkey and Tetyana Sergeeva and Alexandr Sergeev from Ukraine. On the Conference were presented 13 invited lectures, 22 short talks and 35 posters, in total

The History of Target-Controlled Infusion

NARCIS (Netherlands)

Struys, Michel M. R. F.; De Smet, Tom; Glen, John (Iain) B.; Vereecke, Hugo E. M.; Absalom, Anthony R.; Schnider, Thomas W.

Target-controlled infusion (TCI) is a technique of infusing IV drugs to achieve a user-defined predicted (target) drug concentration in a specific body compartment or tissue of interest. In this review, we describe the pharmacokinetic principles of TCI, the development of TCI systems, and technical

Analysis of the Capital Budgeting Practices: Serbian Case

Directory of Open Access Journals (Sweden)

Lidija Barjaktarovic

2016-09-01

Full Text Available This paper addresses two major research questions: which techniques firms in Serbia use for project evaluation, and how the Serbian companies calculate their cost of capital. The authors have created the questionnaire and the sample consisting of 65 companies that responded to the enquiry (out of 392 during the year 2015. The results showed that payback criterion is the most dominant capital budgeting technique used by firms in Serbia. Further, the results revealed that large firms as well as multinational firms are more inclined to use discounted cash flow capital budgeting techniques and other sophisticated techniques. Finally, the authors have concluded that the CAPM is not the dominant method for calculating cost of capital by the companies from the sample analyzing the overall sample. Consequently, skilled human capital, the adequate knowledge and developed procedures may contribute to accepting capital budgeting techniques such as discounted cash flow analysis and other sophisticated techniques by larger portion of the companies in Serbia. Finally, existence of perfect financial market is a necessary precondition for implementing all these contemporary financial concepts and its development has to be posed as one of the priorities in the years to come.

Brand positioning through banking services' offer: Serbian perspective

Directory of Open Access Journals (Sweden)

Novčić Branka

2012-01-01

Full Text Available The subject of this paper relates to the determination of interdependent relationship of the key elements necessary for the positioning of brands in the banking market in Serbia. The main goal of this paper is to analyze the way in which managers of banks in Serbia perceived brand positioning of banks in which they work, and the value of the customer service offer - corporate clients. Research focuses on identifying and comparing the dependent relationships between the key elements of offers' brand positioning: brand awareness, brand associations, perceived quality and brand loyalty. For the purpose of the research presented in this paper on-line surveying techniques was applied. 49 responses were collected form banking managers responsible for corporate clients. Results were analyzed using one-way analysis of variance (ANOVA.Acquired results indicate that there is a strong correlation between the observed elements: awareness of the brand-brand associations, brand association-perceived quality and perceived quality of brand-loyalty. Also, this paper provides an overview of the current position of the banking brands, as well as guidelines for improving the position of banking brands on the Serbian market.

Low-dose factor VIII infusion in Chinese adult haemophilia A patients: pharmacokinetics evidence that daily infusion results in higher trough level than with every-other-day infusion with similar factor VIII consumption.

Science.gov (United States)

Hua, B; Lee, A; Fan, L; Li, K; Zhang, Y; Poon, M-C; Zhao, Y

2017-05-01

Pharmacokinetics (PK) modelling suggests improvement of trough levels are achieved by using more frequent infusion strategy. However, no clinical study data exists to confirm or quantify improvement in trough level, particularly for low-dose prophylaxis in patients with haemophilia A. To provide evidence that low dose daily (ED) prophylaxis can increase trough levels without increasing FVIII consumption compared to every-other-day (EOD) infusion. A cross-over study on 5 IU kg -1 FVIII daily vs. 10 IU kg -1 EOD infusions, each for 14 days was conducted at the PUMCH-HTC. On the ED schedule, trough (immediate prior to infusion), and peak FVIII:C levels (30 min after infusion) were measured on days 1-5; and trough levels alone on days 7, 9, 11 and 13. For the EOD schedule, troughs, peaks and 4-h postinfusion were measured on day 1; troughs and peaks on days 3, 5, and 7; troughs alone on days 9, 11 and 13 and 24-h postinfusion on days 2, 4 and 6. FVIII inhibitors were assessed on days 0 and 14 during both infusion schedules. Six patients were enrolled. PK evidence showed that daily prophylaxis achieved higher (~2 times) steady-state FVIII trough levels compared to EOD with the same total factor consumption. The daily prophylaxis had good acceptability among patients and reduced chronic pain in the joints in some patients. Our PK study shows low-dose factor VIII daily infusion results in higher trough level than with EOD infusion with similar factor VIII consumption in Chinese adult haemophilia A patients. © 2017 John Wiley & Sons Ltd.

An experimental study on the influence of infusion speed on the early mechanism of embolic effect of arterially infused absolute Ethanol in the rat

International Nuclear Information System (INIS)

Han, Joon Koo; Kim, Woo Ho; Lee, Byung Hee; Park, Kil Sun; Park, Jae Hyung; Kim, Chu Wan; Han, Man Chung

1990-01-01

In order to clarify the early mechanism of action of the tissue necrosis induced by intraarterially infused absolute ethanol, abdominal aortography and histopathologic examination after absolute ethanol infusion into aorta at fast (0.4ml/sec) and slow speed (0.04ml/sec) were performed on 22 rats (2 controls, 7 in fast infusion group, 7 in slow infusion group, 3 in fast and 3 in slow infusion groups during aorta compression, respectively). Histopathologic features under the light and scanning electron microscope were correlated with the angiographic findings within 30 minutes after ethanol infusion. The results are as follows : 1. In fast infusion group, histopathologic examination of the kidney showed severe glomerular and tubular damage. Extensive damage on endothelial and medial layer was noted in arteries, and fresh thrombi originated from the damaged arterial wall were seen. 2. Angiographic findings in the fast infusion group were luminal irregularity and early obstruction of large arteries. And circulation time was prolonged. 3. In slow infusion group, histopathologic examination of the kidney showed focal area of severe glomerular and tubular damage on relatively normal background. Endothelial and muscular damage was noted in arteries, but the degree of the damage was less severe than that of the fast infusion group. 4. Angiographic findings in the slow infusion group were focal perfusion defect of the kidney, delayed circulation time, and mild luminal irregularity, but obstruction of the major arteries was not seen

Infusing Systems Thinking into Career Counseling

Science.gov (United States)

Ryan, Charles W.; Tomlin, James H.

2010-01-01

This study examined the role of career counselors in infusing systems thinking into occupational advising. The authors conducted a qualitative review and analysis of selected literature on systems thinking and analyzed trends for adaptation to career counseling practice. This analysis suggests that career counselors need to infuse systems…

Is continuous infusion of imipenem always the best choice?

Science.gov (United States)

Suchánková, Hana; Lipš, Michal; Urbánek, Karel; Neely, Michael N; Strojil, Jan

2017-03-01

Monte Carlo simulations allow prediction and comparison of concentration-time profiles arising from different dosing regimens in a defined population, provided a population pharmacokinetic model has been established. The aims of this study were to evaluate the population pharmacokinetics of imipenem in critically ill patients with hospital-acquired pneumonia (HAP) and to assess the probability of target attainment (PTA) and cumulative fraction of response (CFR) using EUCAST data. A two-compartment model based on a data set of 19 subjects was employed. Various dosage regimens at 0.5-h and 3-h infusion rates and as continuous infusion were evaluated against the pharmacodynamic targets of 20%fT >MIC , 40%fT >MIC and 100%fT >MIC . For the target of 40%fT >MIC , all 0.5-h infusion regimens achieved optimal exposures (CFR ≥ 90%) against Escherichia coli and Staphylococcus aureus, with nearly optimal exposure against Klebsiella pneumoniae (CFR ≥ 89.4%). The 3-h infusions and continuous infusion exceeded 97% CFR against all pathogens with the exception of Pseudomonas aeruginosa and Acinetobacter spp., where the maximum CFRs were 85.5% and 88.4%, respectively. For the 100%fT >MIC target, only continuous infusion was associated with nearly optimal exposures. Higher PTAs for the targets of 40%fT >MIC and 100%fT >MIC were achieved with 3-h infusions and continuous infusion in comparison with 0.5-h infusions; however, continuous infusion carries a risk of not reaching the MIC of less susceptible pathogens in a higher proportion of patients. In critically ill patients with HAP with risk factors for Gram-negative non-fermenting bacteria, maximum doses administered as extended infusions may be necessary. Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

Folk Beliefs, Religion and Spiritualism in Serbian Society in the 19th and first half of the 20th Century

Directory of Open Access Journals (Sweden)

Ana Banić-Grubišić

2016-02-01

Full Text Available Review of the book by Radmila Radić. Narodna verovanja, religija i spiritizam u srpskom društvu 19. i u prvoj polovini 20. veka. [Folk Beliefs, Religion and Spiritualism in Serbian Society in the 19th and first half of the 20th Century]. 2009. Beograd: Institut za noviju istoriju Srbije, pp. 295

Economic Indicators of Condition and Tendencies of Serbian Economy

Directory of Open Access Journals (Sweden)

Zorica SREDOJEVIĆ

2011-12-01

Full Text Available Global economic crisis has, following financial crisis, hit real sector, and as after effect, large number, mostly developed countries in the world are in recession. Serbian industry is also influenced by global economic crisis. Outer debt is significantly and constantly increasing since beginning of transition process. Main cause to it is rather large disproportion between import and export. Trends in structure of outer debt indicate on notable decrease of national debt on account to private one, during whole transition period. On short term there is no significant risk for country on account of outer debt, but for long term elimination of this risk, it is necessary to considerably increase total export. Former policies should be linked to unconventional employment initiatives, as for new labour, as for redundant ones from restructuring economy branches. State has prominent role in transition process, by helping market exhibit its functions through physical and institutional infrastructure, as well trough public sector, removing most of the market obstacles, and stimulating technical-technological development and education.

Krypton 81m infusion studies. Chapter 18

International Nuclear Information System (INIS)

Kaplan, E.; Mayron, L.W.; Friedman, A.M.; Gindler, J.E.

1978-01-01

A technique is described to give a continuous, constant-rate, intravascular infusion of 81 Krsup(m). Modifications of earlier generators included production of sodium-free 81 Rb, the use of a solution of commercial sterile isotonic non-ionic 5% dextrose-in-water as an eluant, the incorporation of a constant-rate infusion pump, and the miniaturization of the generator column and catheter system. Results are presented of studies of 81 Krsup(m) distribution in dogs, using both intravenous and intra-arterial infusion. (author)

Assesment of the Interest Rates in the Serbian Banking Sector

Directory of Open Access Journals (Sweden)

Barjaktarović Lidija

2014-05-01

Full Text Available Lending interest rates (IR in the Serbian market are generally viewed as high. In accordance with the official NBS (National bank of Serbia data for 2010: lending (IR was 10.4% p.a., deposit IR was 4.2% p.a., and spread was 6.3% p.a. At the same time, IR on cross-border loans was 3.7% p.a. It means that the use of cross-border loans was a better solution for companies which were in position to take them. The indicator of IR spread in Serbia got worse and came down to 106th position (it used to be ranked 90th in 2009; WEF. If we analyse the structure of IR spread, we can notice that there is room for decreasing the level of active IR in the area of country risk premium and funding spread. Pearson Correlation shows that IR has strong relation with return on assets and volume of collected deposits i.e. profit margin per product.

Russian attempts on constitutional issue of insurgent Serbia (1804-1813: Part two: Establishment of a Serbian government by Constantine Rodofinikin

Directory of Open Access Journals (Sweden)

Šarkić Srđan

2014-01-01

Full Text Available The second attempt at constitutional organization, called Osnovanije Praviteljstva Sebskago (Establishment of a Serbian Government, was made by Constantine Constantinovich Rodofinikin, a Russian representative of Greek origine, immediatly after his arrival in Serbia (August 2, 1807. It was signed by Karađorđe on August 20, 1807. According to this project, the supreme power in liberated Serbia was to be executed by the Praviteljstvujušči Senat, i.e. a governing senate, composed of three categories of members: military commanders (vojvode, former honorable members of the council (sovjet and elected representatives of the nahiyes (Turkish districts or counties. The first two categories were to be nobles with a lifelong membership in the senate, while the members of the third category were able to achieve nobility only if elected three times into the senate. Karađorđe was to preside over the senate, bearing the title of svetlejši knez, 'sublime prince,' who would have the right of three votes. Rodofinikin did not consider Karađorđe to be an appropriate person to collaborate with. As a leader of the Uprising, responsible for its military success, Karađorđe demanded urgent, concrete and conditionless Russian aid. On the other hand, Karađorđe wanted autonomous and apsolutic power. Rodofinikin in his Establishment of a Serbian Government, gave him only the presidency over the Senate and the right of three votes. According to this Act, Karađorđe's power was neither hereditary, nor for a lifetime. Karađorđe was not at all satisfied with Rodofinikin's document, but he agreed to the Act thinking that it was the necessary price for Russian support. The aim of Rodofinikin, as well as Paulucci, was to ensure Russian influence in Serbia. However, Paulucci wanted to place Russian officers in all of the governing and commanding positions, while Rodofinikin's desire was to create some kind of Serbian aristocracy, faithful to Russia. During his

Somatotype of top-level serbian rhythmic gymnasts.

Science.gov (United States)

Purenović-Ivanović, Tijana; Popović, Ružena

2014-03-27

Body size and build influence performance in many sports, especially in those belonging to the group of female aesthetic sports (rhythmic gymnastics, artistic gymnastics, and figure skating). These sports pose high specific demands upon the functional, energy, motor and psychological capacities of athletes, but also upon the size, body build and composition of the performers, particularly of the top-level female athletes. The study of the top athletes (rhythmic gymnasts, in this case) may provide valuable information on the morphological requirements for achieving success in this sport. Therefore, the main objective of this research was to analyze the somatotype of 40 Serbian top-level rhythmic gymnasts, aged 13.04±2.79, and to form the five age group categories. The anthropometric variables included body height, body mass, the selected diameters, girths and skinfolds, and the Heath-Carter anthropometric somatotype. All of the anthropometric data were collected according to International Biological Programme, and then processed in the Somatotype 1.2. The applied analysis of variance indicated an increase in endomorphic component with age. The obtained results show that the balanced ectomorph is a dominant somatotype, being similar for all of the athletes that took part in the research (3.54-3.24-4.5). These results are in line with the ones obtained in previous studies.

Clinical applications of continuous infusion chemotherapy ahd concomitant radiation therapy

International Nuclear Information System (INIS)

Rosenthal, C.J.; Rotman, M.

1986-01-01

This book presents information on the following topics: theoretical basis and clinical applications of 5-FU as a radiosensitizer; treatment of hepatic metastases from gastro intestingal primaries with split course radiation therapy; combined modality therapy with 5-FU, Mitomycin-C and radiation therapy for sqamous cell cancers; treatment of bladder carcinoma with concomitant infusion chemotherapy and irradiation; a treatment of invasiv bladder cancer by the XRT/5FU protocol; concomitant radiation therapy and doxorubicin by continuous infusion in advanced malignancies; cis platin by continuous infusion with concurrent radiation therapy in malignant tumors; combination of radiation with concomitant continuous adriamycin infusion in a patient with partially excised pleomorphic soft tissue sarcoma of the lower extremeity; treatment of recurrent carcinoma of the paranasal sinuses using concomitant infusion cis-platinum and radiation therapy; hepatic artery infusion for hepatic metastases in combination with hepatic resection and hepatic radiation; study of simultaneous radiation therapy, continuous infusion, 5FU and bolus mitomycin-C; cancer of the esophagus; continuous infusion VP-16, bolus cis-platinum and simultaneous radiation therapy as salvage therapy in small cell bronchogenic carcinoma; and concomitant radiation, mitomycin-C and 5-FU infusion in gastro intestinal cancer

How can the Serbian diaspora contribute much more to the development at home country?

Directory of Open Access Journals (Sweden)

Grečić Vladimir

2016-01-01

Full Text Available This article analyzes the existing contribution of the Serbian diaspora to the development at home country, and features of its major effects as a partner in the process of economic development. No doubt, the spiritus movens of the contemporary and future economic and social progress is and will be the economy of ideas and creativity. The key factors of this new economy are education, research and innovation. To achieve competitiveness in an increasingly global economic environment it is necessary: the adequate supply and quality of the workforce in the field of research and development. In the last two and a half decades, Serbia's brain drain was quite massive. Thus in the Serbian diaspora there are reputable scientists and successful managers in all fields. Diaspora, the people link between countries, can be the source of cooperation. Consequently, the most important is the question of whether and under what conditions Serbia’s brain drain can be reversed to brain gain. The author argue that the diasporas and migrants could play a crucial role in the development of home country, by presentation of their different experiences. Engaging the Diaspora in the development of home country largely depends on the home country. Talents remain an important component of countries’ and businesses’ long-term competitiveness. In support of this thesis, the author presents the most significant and most successful examples of good practice, arguing that this experience can be used in Serbia, of course, taking into account some of its specificities. The question: how they develop, retain and attract talent should therefore remain high on the agenda of policymakers and business leaders for the foreseeable future of Serbia.

Review of 130 years of research on cyanobacteria in aquatic ecosystems in Serbia presented in a Serbian Cyanobacterial Database

Directory of Open Access Journals (Sweden)

Zorica Svirčev

2017-05-01

Full Text Available The presence of toxic cyanobacteria in aquatic ecosystems in the territory of the Republic of Serbia was surveyed over a period of several decades. Increasing attention is being paid to some negative consequences that may be caused by these microorganisms. Information from available literary sources regarding the distribution and frequency of cyanobacteria and their toxins over a period of 130 years, together with the effects on humans and wildlife in aquatic ecosystems, were gathered and incorporated into a Serbian Cyanobacterial Database created for the CYANOCOST Action. This database encompasses information on 65 aquatic ecosystems, including rivers, lakes, ponds, canals, irrigation reservoirs, reservoirs used for drinking water supply and reservoirs used for other purposes. Cyanobacterial blooms were found in almost 80% of the investigated aquatic ecosystems. The analysis of the research showed the presence of more than 70 species, including blooms of 24 species from 13 genera. Five species of cyanobacteria: Microcystis aeruginosa, Aphanizomenon flos-aquae, Planktothrix agardhii, Microcystis flos-aquae and Planktothrix rubescens frequently formed blooms in the investigated waterbodies and cyanotoxins were also detected in some of them, which had certain negative effects. Here, we present an overview of data contained in the Serbian Cyanobacterial Database, concerning cyanobacterial distribution, cyanotoxin production and associated biological effects in different types of water bodies from the Republic of Serbia. Also, recent important and major cases of cyanobacterial blooming in reservoirs used for drinking water supply: at Vrutci and Ćelije, the Aleksandrovac irrigation reservoir, the Ponjavica River and Lake Palić, including systematic research on the Lake Ludoš and few fishponds are further described. It can be concluded that cyanobacteria and cyanotoxins are omnipresent in different water bodies throughout the Republic of Serbia

Canadian Palliative Community Milrinone Infusions: A Case Series.

Science.gov (United States)

Reimche, Ruthanne; Salcedo, Daniel

2016-01-01

Abstract Symptom managementfor end-of-life heartfailure (HF) patients is a significant concern. Currently, Canadian practice does not support community milrinone therapy in end-of-life HF patients. Two patients had severe HF that was unresponsive to optimal medications. Further optimization and furosemide infusions were ineffective for symptom management. Both patients' symptoms were better controlled with optimal medication, furosemide, and milrinone infusions. A tailored discharge plan was developed to assist with community milrinone infusions. We discuss the challenges and successes of transitioning two patients to the community. By providing symptom management and meaningful patient and family experience, both patients were able to die in a setting of their choosing. Milrinone infusions as a bridge to end of life may improve symptoms and quality of life. Select patients may benefit from milrinone infusions with resources put in place; these end-of-life HF patients can be supported in the community.

A new infusion pathway intactness monitoring system.

Science.gov (United States)

Ogawa, Hidekuni; Yonezawa, Yoshiharu; Maki, Hiromichi; Ninomiya, Ishio; Sata, Koji; Hamada, Shingo; Caldwell, W Morton

2006-01-01

A new infusion pathway monitoring system has been developed for hospital and home use. The system consists of linear integrated circuits and a low-power 8-bit single chip microcomputer which constantly monitors the infusion pathway intactness. An AC (alternating current) voltage is induced on the patient's body by electrostatic coupling from the normal 100 volt, 60 Hz AC power line wiring field in the patient's room. The induced AC voltage can be recorded by a main electrode wrapped around the infusion polyvinyl chloride tube. A reference electrode is wrapped on the electrode to monitor the AC voltage around the main electrode. If the injection needle or infusion tube becomes detached, then the system detects changes in the induced AC voltages and alerts the nursing station, via the nurse call system or PHS (personal handy phone system).

Comparison of the intracoronary continuous infusion method using a microcatheter and the intravenous continuous adenosine infusion method for inducing maximal hyperemia for fractional flow reserve measurement.

Science.gov (United States)

Yoon, Myeong-Ho; Tahk, Seung-Jea; Yang, Hyoung-Mo; Park, Jin-Sun; Zheng, Mingri; Lim, Hong-Seok; Choi, Byoung-Joo; Choi, So-Yeon; Choi, Un-Jung; Hwang, Joung-Won; Kang, Soo-Jin; Hwang, Gyo-Seung; Shin, Joon-Han

2009-06-01

Inducing stable maximal coronary hyperemia is essential for measurement of fractional flow reserve (FFR). We evaluated the efficacy of the intracoronary (IC) continuous adenosine infusion method via a microcatheter for inducing maximal coronary hyperemia. In 43 patients with 44 intermediate coronary lesions, FFR was measured consecutively by IC bolus adenosine injection (48-80 microg in left coronary artery, 36-60 microg in the right coronary artery) and a standard intravenous (IV) adenosine infusion (140 microg x min(-1) x kg(-1)). After completion of the IV infusion method, the tip of an IC microcatheter (Progreat Microcatheter System, Terumo, Japan) was positioned at the coronary ostium, and FFR was measured with increasing IC continuous adenosine infusion rates from 60 to 360 microg/min via the microcatheter. Fractional flow reserve decreased with increasing IC adenosine infusion rates, and no further decrease was observed after 300 microg/min. All patients were well tolerated during the procedures. Fractional flow reserves measured by IC adenosine infusion with 180, 240, 300, and 360 microg/min were significantly lower than those by IV infusion (P < .05). Intracoronary infusion at 180, 240, 300, and 360 microg/min was able to shorten the times to induction of optimal and steady-stable hyperemia compared to IV infusion (P < .05). Functional significances were changed in 5 lesions by IC infusion at 240 to 360 microg/min but not by IV infusion. The results of this study suggest that an IC adenosine continuous infusion method via a microcatheter is safe and effective in inducing steady-state hyperemia and more potent and quicker in inducing optimal hyperemia than the standard IV infusion method.

Inhibition of endogenous lactate turnover with lactate infusion in humans

International Nuclear Information System (INIS)

Searle, G.L.; Feingold, K.R.; Hsu, F.S.; Clark, O.H.; Gertz, E.W.; Stanley, W.C.

1989-01-01

The extent to which lactate infusion may inhibit endogenous lactate production, though previously considered, has never been critically assessed. To examine this proposition, single injection tracer methodology (U- 14 C Lactate) has been used for the estimation of lactate kinetics in 12 human subjects under basal conditions and with the infusion of sodium lactate. The basal rate of lactate turnover was measured on a day before the study with lactate infusion, and averaged 63.7 + 5.5 mg/kg/h. Six of these individuals received a stable lactate infusion at an approximate rate of 160 mg/kg/h, while the remaining six individuals were infused at the approximate rate of 100 mg/kg/h. It has been found that stable lactate infused at rates approximating 160 mg/kg/h consistently produced a complete inhibition of endogenous lactate production. Infusion of lactate at 100 mg/kg/h caused a lesser and more variable inhibition of endogenous lactate production (12% to 64%). In conclusion, lactate infusion significantly inhibits endogenous lactate production

Síndrome da infusão do propofol Síndrome de la infusión del propofol Propofol infusion syndrome

Directory of Open Access Journals (Sweden)

Fabiano Timbó Barbosa

2007-10-01

Full Text Available JUSTIFICATIVA E OBJETIVOS: A síndrome da infusão do propofol tem sido descrita como uma síndrome rara e quase sempre fatal que ocorre após infusão prolongada desse fármaco. Ela pode resultar em acidose metabólica grave, rabdomiólise, colapso cardiovascular e morte. O objetivo deste artigo foi mostrar aspectos relacionados com a síndrome da infusão do propofol por meio da revisão de literatura. CONTEÚDO: Estão definidas as características da síndrome da infusão do propofol quanto à fisiopatologia, características clínicas, tratamento e recomendações de dose para pacientes gravemente enfermos. CONCLUSÕES: O propofol deve ser usado com cautela quando se planeja seu uso sob regime de infusão contínua por períodos prolongados. O surgimento de sinais sugestivos da síndrome da infusão do propofol indica a suspensão imediata do fármaco e início de medidas de suporte.JUSIFICATIVA Y OBJETIVOS: El síndrome de la infusión del propofol ha sido descrito como un síndrome raro y frecuentemente fatal que ocurre después de la infusión prolongada de ese fármaco. Puede resultar en acidez metabólica grave, rabdomiólisis, colapso cardiovascular y deceso. El objetivo de este artículo fue mostrar aspectos relacionados al síndrome de la infusión del propofol a través de la revisión de la literatura. CONTENIDO: Están definidas las características del síndrome de la infusión del propofol en cuanto a la fisiopatología, características clínicas, tratamiento y recomendaciones de dosis para pacientes gravemente enfermos. CONCLUSIONES: El propofol debe ser usado con cautela cuando se planea su uso bajo el régimen de infusión continua por períodos prolongados. El aparecimiento de señales sugestivas del síndrome de la infusión del propofol indica la suspensión inmediata del fármaco y el inicio de medidas de soporte.BACKGROUND AND OBJECTIVES: Propofol infusion syndrome has been described as a rare, and frequently fatal

Effect of Insulin Infusion on Liver Protein Synthesis during Hemodialysis

DEFF Research Database (Denmark)

Reinhard, Mark; Frystyk, Jan; Jespersen, Bente

2011-01-01

Background Hemodialysis (HD) is a catabolic procedure that may contribute to the high frequency of protein-energy wasting among patients receiving maintenance HD. The present study investigated the additional effect of glucose and glucose-insulin infusion on liver protein synthesis during HD...... compared with a meal alone. Methods In a randomized cross-over study with three arms, 11 non-diabetic HD patients were assigned to receive a conventional HD session with either: • no treatment (NT) • IV infusion of glucose (G) • IV infusion of glucose-insulin (GI) During infusions blood glucose levels were...... maintained at 8.0-10.0 mmol/L by additional glucose infusion. Glucose and glucose-insulin infusions were commenced 2 h prior to HD and continued throughout the HD session. Fasting blood samples were collected at baseline before infusion and followed by the only meal allowed during the study. Results Blood...

Work Engagement in Serbia: Psychometric Properties of the Serbian Version of the Utrecht Work Engagement Scale (UWES)

OpenAIRE

Petrović, Ivana B.; Vukelić, Milica; Čizmić, Svetlana

2017-01-01

Work engagement is defined as a positive, affective-motivational state of work-related well-being characterized by vigor, dedication and absorption. The Utrecht Work Engagement Scale (UWES) is the most frequently used measure of work engagement. The aim of this study was to analyze the psychometric properties of the Serbian versions of the UWES-17 and UWES-9. The sample consisted of 860 employees from a number of organizations and jobs across Serbia. Based on the UWES-17 findings, the data co...

Three minute versus six minute adenosine infusion in myocardial perfusion scintigraphy

International Nuclear Information System (INIS)

Gopinath, G.; Naojee, S.A.; Croasdale, J.; Johnson, G.; Hilson, A.J.W.; Buscombe, J.R.

2003-01-01

Pharmacological stress imaging techniques are used widely in clinical nuclear cardiology for evaluation of ischemic heart disease. Adenosine is often used but is expensive and causes significant side effects .The aim of this retrospective review was to study the tolerance and efficacy, of adenosine infusion of a 3 minute (min) versus the conventional 6 min stress protocol and to assess the cost efficiency of the 3 min protocol. Three hundred thirty one patients had myocardial scintigraphy using adenosine as a stressing agent. Blood pressure, heart rate and ECG were recorded at baseline and during the test. Symptoms (flushing, headache, chest pain, dyspnoea, neck pain) were recorded throughout the adenosine infusion. All the patients had had either 6 min or 3 min adenosine infusion at 140 mg/kg per minute. 169 of them had side effects. Flushing (32% at 3 min vs 50 % at 6 min, p<0.05), headache (11.5% at 3 min vs 7 % at 6 min p-not significant-ns), chest pain (8% at 3 min vs 13 % at 6 min, ns), dyspnoea (7% at 3 min vs %10 at 6 min, ns), ECG changes (10% at 3 min vs 28% at 6 min, p<0.05), neck pain (4.5% at 3 min vs 9% at 6 min, ns), abdominal discomfort (3% at 3 min vs 3% at 6 min, ns) and fall in blood pressure (6% at 3 min vs 8.5% at 6 min, ns). The change in heart rate was not significant with either protocol. The 6 min and 3 min infusions of adenosine had similar accuracy (73% vs 70%) for the detection of coronary artery disease. The patients tolerated the 3 min protocol better with only 40% of the patients having minimal side effects compared with 60% for the 6 mon protocol. The 3 min protocol is also cost effective as it uses less adenosine and therefore reduces total costs by 40 US$ per patient. (author)

Development of energy management system - Case study of Serbian car manufacturer

International Nuclear Information System (INIS)

Gordic, Dusan; Babic, Milun; Jovicic, Nebojsa; Sustersic, Vanja; Koncalovic, Davor; Jelic, Dubravka

2010-01-01

The procedure of development of energy management system applied to an existing company (Serbian car producer 'Zastava') is shown in the paper. The aim of the paper is to provide a guideline for entrepreneurs in metal-working industry in implementing energy management system. First of all, paper includes: critical analysis of existing energy management system (energy matrix), principles of effective energy management organization (with energy manager and energy team in its structure) and energy management politics. Based on the results of energy auditing and performed technological and economical feasibility studies several energy saving measures related to different energy sources (steam, hot water, compressed air, electricity and water) were proposed, implemented and valuated. The proposed measures are not exclusively related to car assembly industry; they can be easily applied to other metal-working facilities with minor modifications. Such energy management system reduces energy costs and increase profitability of a factory.

Lipolytic response to glucose infusion in human subjects

International Nuclear Information System (INIS)

Wolfe, R.R.; Peters, E.J.

1987-01-01

The authors have determined the effect of various rates of glucose infusion on the rates of release of glycerol (R/sub a/ glycerol), free fatty acids (R/sub a/ FFA), and on energy metabolism in normal human volunteers. Plasma kinetics were determined with use of the stable isotopic tracers D-5-glycerol and [1- 13 C]palmitate, and energy metabolism was determined by indirect calorimetry. The effect of glucose infusion on R/sub a/ glycerol and R/sub a/ FFA was dose-dependent. At 4 mg x kg -1 x min -1 , both R/sub a/ glycerol and R/sub a/ FFA were suppressed; at 8 mg x kg -1 x min -1 , R/sub a/ FFA was even more depressed, but R/sub a/ glycerol was similar to the value during the 4 mg x kg -1 x min -1 infusion. At all infusion rates tested, the amount of potential energy available from the sum of the glucose infusion and endogenously mobilized fat was always greater than when no glucose was infused. Glucose decreased fat mobilization by both inhibiting lipolysis and stimulating reesterification, thus causing a significant increase in triglyceride-fatty acid substrate cycling within the adipose tissue. Plasma insulin was determined by radioimmunoassay

The impact of an educational film on promoting knowledge and attitudes toward HIV in soldiers of the Serbian armed forces

Directory of Open Access Journals (Sweden)

Jadranin Željko

2015-01-01

Full Text Available Background/Aim. Millions of soldiers around the world represent one of the most vulnerable populations regarding exposure to human immunodeficiency virus (HIV infection. The programs for HIV prevention remain the most viable approach to reducing the spread of HIV infection. Very few studies have tested the effectiveness of HIV preventive interventions undertaken in military population. The aim of this study was to determine the effectiveness of educational film to transfer knowledge about HIV infection to soldiers. Methods. We performed a quasi-experimental study among 102 soldiers of the Serbian Armed Forces. The experimental intervention consisted of the HIV knowledge pre-questionnaire, watching a film on HIV knowledge, then the post-HIV knowledge questionnaire. The results of pre-and post-HIV knowledge questionnaires were compared. Results. There were 23 questions in the test. The average total score on the questionnaire before watching the film was 18.23 and after watching it was 20.14, which was statistically significant difference (p < 0.001. Conclusions. The results of the study show that viewing a film on HIV infection is an effective method of transferring knowledge about HIV to the Serbian military population.

Comparison of infusion pumps calibration methods

Science.gov (United States)

Batista, Elsa; Godinho, Isabel; do Céu Ferreira, Maria; Furtado, Andreia; Lucas, Peter; Silva, Claudia

2017-12-01

Nowadays, several types of infusion pump are commonly used for drug delivery, such as syringe pumps and peristaltic pumps. These instruments present different measuring features and capacities according to their use and therapeutic application. In order to ensure the metrological traceability of these flow and volume measuring equipment, it is necessary to use suitable calibration methods and standards. Two different calibration methods can be used to determine the flow error of infusion pumps. One is the gravimetric method, considered as a primary method, commonly used by National Metrology Institutes. The other calibration method, a secondary method, relies on an infusion device analyser (IDA) and is typically used by hospital maintenance offices. The suitability of the IDA calibration method was assessed by testing several infusion instruments at different flow rates using the gravimetric method. In addition, a measurement comparison between Portuguese Accredited Laboratories and hospital maintenance offices was performed under the coordination of the Portuguese Institute for Quality, the National Metrology Institute. The obtained results were directly related to the used calibration method and are presented in this paper. This work has been developed in the framework of the EURAMET projects EMRP MeDD and EMPIR 15SIP03.

Continuous indomethacin infusion may be less effective than bolus infusions for ductal closure in very low birth weight infants

NARCIS (Netherlands)

de Vries, NKS; Jagroep, FK; Jaarsma, AS; Elzenga, NJ; Bos, AF

The effectiveness of continuous indomethacin (INDO) infusion versus bolus infusions for closure of patent ductus arteriosus (PDA) was investigated. The study design was an open-label case series (continuous INDO) with historic controls matched for gestational age (bolus INDO). Ductal closure rates

Vocal fold submucosal infusion technique in phonomicrosurgery.

Science.gov (United States)

Kass, E S; Hillman, R E; Zeitels, S M

1996-05-01

Phonomicrosurgery is optimized by maximally preserving the vocal fold's layered microstructure (laminae propriae). The technique of submucosal infusion of saline and epinephrine into the superficial lamina propria (SLP) was examined to delineate how, when, and why it was helpful toward this surgical goal. A retrospective review revealed that the submucosal infusion technique was used to enhance the surgery in 75 of 152 vocal fold procedures that were performed over the last 2 years. The vocal fold epithelium was noted to be adherent to the vocal ligament in 29 of the 75 cases: 19 from previous surgical scarring, 4 from cancer, 3 from sulcus vocalis, 2 from chronic hemorrhage, and 1 from radiotherapy. The submucosal infusion technique was most helpful when the vocal fold epithelium required resection and/or when extensive dissection in the SLP was necessary. The infusion enhanced the surgery by vasoconstriction of the microvasculature in the SLP, which improved visualization during cold-instrument tangential dissection. Improved visualization facilitated maximal preservation of the SLP, which is necessary for optimal pliability of the overlying epithelium. The infusion also improved the placement of incisions at the perimeter of benign, premalignant, and malignant lesions, and thereby helped preserve epithelium uninvolved by the disorder.

Infusion of radionuclides throughout pregnancy

International Nuclear Information System (INIS)

Mountford-Lister, P.G.; Lambert, B.E.; Milner, A.C.; Kang, X.Z.

1992-01-01

This work is part of a long-term study to examine the cancer incidence in the offspring of mice exposed to 239 Pu or 147 Pm throughout pregnancy. The need to model the human intake scenario and the possibility of a critical period during uterine development necessitates constant availability of radionuclides throughout pregnancy. Various methods (multiple daily injections, infusion by external cannula and infusion by indwelling osmotic pump) have been examined and osmotic infusion pumps chosen. These pumps result in a near-constant blood concentration for up to 21 days. Part of the study is the estimation of dose to the critical haemopoietic tissues of the pup from a knowledge of the radionuclide distribution and kinetics. At present the distribution has been followed from birth to 180 days. Activity in the suckling pups at 7 days old is around 1 percent of the infused activity, though most of this is accounted for by the contents of the stomach and gastrointestinal tract. The liver and femur account for around 0.025 percent and 0.012 percent respectively per pup. Activity increases in both liver and femur during lactation after which both concentration and activity fall with time. Long-term studies with the pups of dams exposed to a range of 239 Pu concentrations between 0-70 kBq/kg are underway. Correlation of average organ dose with tumour incidence will be determined at completion of the life-span study. (Author) 39 refs., 5 tabs., 6 figs

Cross-Border Landscape: Construction of Natural Heritage and Local Development at Bulgarian-Serbian Borderlands

Directory of Open Access Journals (Sweden)

I. Markov

2015-08-01

Full Text Available Normally nature is examined as a phenomenon which is subject to natural laws; it belongs to the field of natural sciences. In constructivist perspective the environment is subsumed under the symbolism of humans’ tradition and culture. From such point of view the very notion of nature is unthinkable without taking into account its existence and understanding in a specific social, economic and cultural context of definite time, space and society. In the proposed paper I proceed from this paradigm in examination of a definite natural landscape which, however, is divided by the political border. The research attention is focused on a region of Bulgarian-Serbian borderlands – the area where the Erma River flows. The river takes its sources in Serbia and though it is not very long, it is notable for passing the Bulgarian-Serbian border twice, and for its two remarkable gorges – the Gorge of Tran in Bulgaria and the Gorge of Poganovo in Serbia. During the socialist period this border region was under strong military and police control. The crossing of the border was formally impossible; the borderlands remained peripheral industrially undeveloped areas and were putted under strong depopulation. However, the lands on either side of the border preserved its pristine nature. During the last two decades the preserved natural landscape and certain nature objects have been turned into more important landmarks and included in the value scale of local communities as symbols and heritage. In result, the above mentioned gorges have become more important part of strategic priorities in the local policies of revival of these economically undeveloped borderlands in the Western Bulgaria and Eastern Serbia. Nowadays the local efforts are uniting through different joint cross-border projects and activities in the sphere of nature preservation and eco-tourism.

Problem continuity in discontinuity of development of Serbian industry

Directory of Open Access Journals (Sweden)

Šljukić Marica

2017-01-01

Full Text Available In this paper the author uses a comparative analysis in order to show the discontinuity in the process of the industrial development of the Serbian society, as well as to point out the fact that the almost same problems have not been mastered throughout the whole process of industrialization. Besides the historical data, the data of the empirical research are used. The goal of the empirical research was to determine the real and the possible degree and intensity of the influence of the structural social changes to the organizing of industrial work. The research had been done from 2011 to 2013 using the multiple case study method, and it included six organizations from different sectors of industry. By comparison of different phases of the industrial development in Serbia the author concludes the continuity of the following problems: accumulation of capital, technical and technological underdevelopment and dependence, raw materials dependence, and the deficit of the competent work force (especially managers. The biggest and the basic problem, which encompasses all four problems mentioned above, has been the absence of the strategy of the industrial development throughout the whole process of this development.

Design of Infusion Schemes for Neuroreceptor Imaging

DEFF Research Database (Denmark)

Feng, Ling; Svarer, Claus; Madsen, Karine

2016-01-01

for bolus infusion (BI) or programmed infusion (PI) experiments. Steady-state quantitative measurements can be made with one short scan and venous blood samples. The GABAA receptor ligand [(11)C]Flumazenil (FMZ) was chosen for this purpose, as it lacks a suitable reference region. Methods. Five bolus [(11)C...... state was attained within 40 min, which was 8 min earlier than the optimal BI (B/I ratio = 55 min). Conclusions. The system can design both BI and PI schemes to attain steady state rapidly. For example, subjects can be [(11)C]FMZ-PET scanned after 40 min of tracer infusion for 40 min with venous...

Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials

Directory of Open Access Journals (Sweden)

Van Arendonk Kyle J

2011-06-01

Full Text Available Abstract Background The emergence of multi-drug resistant Gram-negatives (MDRGNs coupled with an alarming scarcity of new antibiotics has forced the optimization of the therapeutic potential of available antibiotics. To exploit the time above the minimum inhibitory concentration mechanism of β-lactams, prolonging their infusion may improve outcomes. The primary objective of this meta-analysis was to determine if prolonged β-lactam infusion resulted in decreased mortality and improved clinical cure compared to intermittent β-lactam infusion. Methods Relevant studies were identified from searches of MEDLINE, EMBASE, and CENTRAL. Heterogeneity was assessed qualitatively, in addition to I2 and Chi-square statistics. Pooled relative risks (RR and 95% confidence intervals (CI were calculated using Mantel-Haenszel random-effects models. Results Fourteen randomized controlled trials (RCTs were included. Prolonged infusion β-lactams were not associated with decreased mortality (n= 982; RR 0.92; 95% CI:0.61-1.37 or clinical cure (n = 1380; RR 1.00 95% CI:0.94-1.06 compared to intermittent infusions. Subgroup analysis for β-lactam subclasses and equivalent total daily β-lactam doses yielded similar results. Most studies had notable methodological flaws. Conclusions No clinical advantage was observed for prolonged infusion β-lactams. The limited number of studies with MDRGNs precluded evaluation of prolonged infusion of β-lactams for this subgroup. A large, multicenter RCT with critically ill patients infected with MDRGNs is needed.

Intravenous lidocaine infusion--a new treatment of chronic painful diabetic neuropathy?

DEFF Research Database (Denmark)

Kastrup, J; Petersen, P; Dejgård, A

1987-01-01

after lidocaine infusion compared to after saline infusion (P less than 0.05 and P less than 0.02, respectively). The duration of the individual effect ranged from 3 to 21 days. Lidocaine infusion had no effect on the objective measurements of neuropathy. Intravenous lidocaine infusion seems to be a new...

Measuring vulnerability to depression: The Serbian scrambled sentences test - SSST

Directory of Open Access Journals (Sweden)

Novović Zdenka

2014-01-01

Full Text Available The goal of this study was to establish whether the SSST, a Serbian language scrambled sentences instrument, is a reliable measure of depressive cognitive bias, and whether it captures the suppression tendency as participants exert the additional cognitive effort of memorizing a six-digit number while completing the task. The sample consisted of 1071 students, randomly assigned into two groups. They completed the SSST divided into two blocks of 28 sentences, together with additional cognitive task during either the first or second block, and after that a number of instruments to establish validity of the SSST. The test was shown to be a reliable instrument of depressive cognitive bias. As a measure of suppression the SSST performed partly as expected, only when load was applied in the second half of the test, and fatigue and cognitive effort enhanced suppression. The advantages of the test versus self-description measures were discussed. [Projekat Ministarstva nauke Republike Srbije, br. 179006: Hereditary, environmental, and psychological factors of mental health

The impact of foreign investors on the Serbian stock market

Directory of Open Access Journals (Sweden)

Rakočević Rade

2016-01-01

Full Text Available Frontier markets, such as Serbia, which are at the early stages of development, are characterized by very low level of solvency, absence of corporate management rules and reports to the public, insufficiently developed regulations, as well as significant participation of foreign portfolio investors in the exchange. Those are usually foreign investment funds specialized in risky investments at such markets; they apply the principle of geographic portfolio diversification in their investment policy. At the Belgrade Stock Exchange, foreign investors have been present at the stock market since 2002 and they participated in high volumes in stock buying during the stock market growth in the period from 2002 to 2007, whereas during the crisis at the Serbian capital market from 2008 to 2010 there was a significant increase in foreign investors' participation on the selling side and a withdrawal from the Belgrade Stock Exchange. Such behavior of foreign investors was initially prompted by local factors, but was intensified by the global financial crisis and will be analyzed in this paper.

Radiation shielding properties of high performance concrete reinforced with basalt fibers infused with natural and enriched boron

Energy Technology Data Exchange (ETDEWEB)

Zorla, Eyüp; Ipbüker, Cagatay [University of Tartu, Institute of Physics (Estonia); Biland, Alex [US Basalt Corp., Houston (United States); Kiisk, Madis [University of Tartu, Institute of Physics (Estonia); Kovaljov, Sergei [OÜ Basaltest, Tartu (Estonia); Tkaczyk, Alan H. [University of Tartu, Institute of Physics (Estonia); Gulik, Volodymyr, E-mail: volodymyr.gulik@gmail.com [Institute for Safety Problems of Nuclear Power Plants, Lysogirska 12, of. 201, 03028 Kyiv (Ukraine)

2017-03-15

Highlights: • Basalt fiber infused with natural and enriched boron in varying proportions. • Gamma-ray attenuation remains stable with addition of basalt-boron fiber. • Improvement in neutron shielding for nuclear facilities producing fast fission spectrum. • Basalt-boron fiber could decrease the shielding thickness in thermal spectrum reactors. - Abstract: The importance of radiation shielding is increasing in parallel with the expansion of the application areas of nuclear technologies. This study investigates the radiation shielding properties of two types of high strength concrete reinforced with basalt fibers infused with 12–20% boron oxide, containing varying fractions of natural and enriched boron. The gamma-ray shielding characteristics are analyzed with the help of the WinXCom, whereas the neutron shielding characteristics are modeled and computed by Monte Carlo Serpent code. For gamma-ray shielding, the attenuation coefficients of the studied samples do not display any significant variation due to the addition of basalt-boron fibers at any mixing proportion. For neutron shielding, the addition of basalt-boron fiber has negligible effects in the case of very fast neutrons (14 MeV), but it could considerably improve the neutron shielding of concrete for nuclear facilities producing a fast fission spectrum (e.g. with reactors as BN-800, FBTR) and thermal neutron spectrum (Light Water Reactors (LWR)). It was also found that basalt-boron fiber could decrease the thickness of radiation shielding material in thermal spectrum reactors.

Radiation shielding properties of high performance concrete reinforced with basalt fibers infused with natural and enriched boron

International Nuclear Information System (INIS)

Zorla, Eyüp; Ipbüker, Cagatay; Biland, Alex; Kiisk, Madis; Kovaljov, Sergei; Tkaczyk, Alan H.; Gulik, Volodymyr

2017-01-01

Highlights: • Basalt fiber infused with natural and enriched boron in varying proportions. • Gamma-ray attenuation remains stable with addition of basalt-boron fiber. • Improvement in neutron shielding for nuclear facilities producing fast fission spectrum. • Basalt-boron fiber could decrease the shielding thickness in thermal spectrum reactors. - Abstract: The importance of radiation shielding is increasing in parallel with the expansion of the application areas of nuclear technologies. This study investigates the radiation shielding properties of two types of high strength concrete reinforced with basalt fibers infused with 12–20% boron oxide, containing varying fractions of natural and enriched boron. The gamma-ray shielding characteristics are analyzed with the help of the WinXCom, whereas the neutron shielding characteristics are modeled and computed by Monte Carlo Serpent code. For gamma-ray shielding, the attenuation coefficients of the studied samples do not display any significant variation due to the addition of basalt-boron fibers at any mixing proportion. For neutron shielding, the addition of basalt-boron fiber has negligible effects in the case of very fast neutrons (14 MeV), but it could considerably improve the neutron shielding of concrete for nuclear facilities producing a fast fission spectrum (e.g. with reactors as BN-800, FBTR) and thermal neutron spectrum (Light Water Reactors (LWR)). It was also found that basalt-boron fiber could decrease the thickness of radiation shielding material in thermal spectrum reactors.

Forearm metabolism during infusion of adrenaline

DEFF Research Database (Denmark)

Simonsen, L; Stefl, B; Bülow, J

2000-01-01

Human skeletal muscle metabolism is often investigated by measurements of substrate fluxes across the forearm. To evaluate whether the two forearms give the same metabolic information, nine healthy subjects were studied in the fasted state and during infusion of adrenaline. Both arms were...... catheterized in a cubital vein in the retrograde direction. A femoral artery was catheterized for blood sampling, and a femoral vein for infusion of adrenaline. Forearm blood flow was measured by venous occlusion strain-gauge plethysmography. Forearm subcutaneous adipose tissue blood flow was measured...... by the local 133Xe washout method. Metabolic fluxes were calculated as the product of forearm blood flow and a-v differences of metabolite concentrations. After baseline measurements, adrenaline was infused at a rate of 0.3 nmol kg-1 min-1. No difference in the metabolic information obtained in the fasting...

THE OWNERSHIP STRUCTURE AS A CORPORATE GOVERNANCE MECHANISM IN SERBIAN HOTELS

Directory of Open Access Journals (Sweden)

Pero Petrovic

2010-06-01

Full Text Available This article analyses the development in Serbien tourism sector during the last decade. The article is focused on the ownership structure and company performance in the light of corporate governance theory and the actuel privatisation process. Previous research has proven that Serbien state is a poor and pasive owner,whereas private owners and amployees are more active and more interested in their company’s economic performance. This article shows that the transition to private ownership in the Serbian hotels sector has not been finished. Consequently, state-owned and investment funds remain important owners of Serbien hotels. The financial performance of hotel companies is below average in the economy and can be correlated with the current ownership structure. Since the current ownership structure has a negative impact on the hotel sector competitiveness, an ownership change is needed to boost the sector’s competitivensess and the competitivensess of Serbia as tourist destination.

ArtsIN: Arts Integration and Infusion Framework

Science.gov (United States)

Hartle, Lynn C.; Pinciotti, Patricia; Gorton, Rebecca L.

2015-01-01

Teaching to meet the diverse learning needs of twenty-first century, global learners can be challenging, yet a growing body of research points to the proved successes of arts-infused and integrated curricula, especially for building capacity for learning and motivation. This article presents the ArtsIN: Arts Integration and Infusion framework, a…

Bupivacaine constant continuous surgical wound infusion versus continuous epidural infusion for post cesarean section pain, randomized placebo-controlled study

Directory of Open Access Journals (Sweden)

Hossam A. ELShamaa

2016-10-01

Conclusion: The current study demonstrated that bupivacaine administered by continuous epidural infusion provided a significantly lower pain scores with mobilization, and hence better analgesia for post cesarean section pain in the first postoperative day compared to continuous bupivacaine wound infusion through fenestrated catheter using the constant flow PainFusor system.

Delivery interaction between co-infused medications: an in vitro modeling study of microinfusion.

Science.gov (United States)

Tsao, Amy C; Lovich, Mark A; Parker, Michael J; Zheng, Hui; Peterfreund, Robert A

2013-01-01

To test the hypothesis that steady-state drug delivery by continuous infusion is predictably affected by a second drug infusion in the same lumen. Clinicians commonly administer two drugs by continuous infusion through one central venous catheter lumen (co-infusion). To limit fluid delivery, low flow rate carriers transport concentrated drug solutions; a method called microinfusion. How microinfusion delivery of one drug is affected by a second drug infusion has not been explored. Two water-soluble dyes, tartrazine and erioglaucine, infused at 3 ml · h(-1), modeled drug delivery through a four stopcock linear manifold and catheter lumen. A pump drove a carrier fluid (10 ml · h(-1)). After tartrazine reached steady-state delivery, erioglaucine entered downstream or upstream of the tartrazine infusion. Quantitative spectrophotometry measured dye delivery. Starting erioglaucine's infusion upstream of tartrazine's entry caused a transient tartrazine bolus (duration 10 min, peak drug delivery 20% higher than target levels). Starting erioglaucine's infusion downstream produced a similar amplitude, briefer, bolus. Stopping the erioglaucine infusion caused a transient reduction in tartrazine delivery. Measured delivery profiles were comparable to prediction models. We confirmed the hypothesis that delivery of one infused drug is transiently affected by starting or stopping a second drug infusion in the same line. The magnitude of the changes can be estimated quantitatively. The clinical impact depends on the drugs being co-infused and patient sensitivity, but could be clinically important; the findings have safety implications for infused medication delivery to critically ill or anesthetized children. We recommend minimizing infusion system dead volumes, connecting the most essential infusion(s) to the main fluid pathway as close as possible to the patient, and recognizing the potential for unintended alterations in delivery when multiple drugs co-infuse. © 2012

CYP3A5 Polymorphism In Serbian Paediatric Epileptic Patients On Carbamazepine Treatment

Directory of Open Access Journals (Sweden)

Milovanovic Dragana Dragas

2015-06-01

Full Text Available Carbamazepine exhibits significant inter-individual variability in its efficacy and safety, which leads to unpredictable therapy outcomes for the majority of patients. Although its complex biotransformation depends on CYP3A5 activity, evidence of association between carbamazepine treatment outcomes and CYP3A5 functional variations remains inconclusive. The aim of the present study was to investigate the distribution of two of the functionally important CYP3A5 variants *2 and *3 as well as their effects on carbamazepine dose requirements, plasma concentrations and clearance in a Serbian population. The study involved 40 paediatric epileptic patients on steady-state carbamazepine treatment. Genotyping was conducted using the PCR-RFLP method, and carbamazepine plasma concentrations were determined using the HPLC method. CYP3A5*2 and *3 polymorphisms were found at frequencies of 0.0% and 97.5%, respectively, which corresponds well to previously published data for Caucasians. No differences in CYP3A5*3 allele frequencies were detected among epileptic patients in comparison to healthy volunteers within similar ethnic populations (p>0.08, indicating that CYP3A5 polymorphism does not represent a risk factor for epilepsy development. There was an observed tendency towards lower dosage requirements (mean±SD: 15.06±4.45 mg/kg vs. 18.74±5.55 mg/kg; p=0.26, higher plasma concentrations (mean±SD: 0.45±0.13 mg/kg vs. 0.38±0.03 mg/kg; p=0.47 and lower clearance (mean±SD: 0.14±0.05 mg/kg vs. 0.15±0.01 mg/kg; p=0.79 of carbamazepine in homozygous carriers of CYP3A5*3/*3 compared to heterozygous CYP3A5*1A/*3 Serbians. Because these genotype groups did not differ significantly in terms of their carbamazepine pharmacokinetics parameters, the proposed effects of CYP3A5*3 on carbamazepine metabolism could not be confirmed.

Continuous infusion of chemotherapy: focus on 5-fluorouracil and fluorodeoxyuridine

NARCIS (Netherlands)

Poorter, R. L.; Bakker, P. J.; Veenhof, C. H.

1998-01-01

Continuous infusion of chemotherapy is one of the developments to try to improve the treatment of metastatic cancer. There is a sound theoretical rationale to deliver cytotoxic drugs as a continuous infusion. Furthermore, the development of reliable venous access devices and portable infusion pumps

Safe and tolerable one-hour pamidronate infusion for multiple myeloma patients

Directory of Open Access Journals (Sweden)

Dimitrios Chantzichristos

2008-09-01

Full Text Available Dimitrios Chantzichristos, Andréasson Björn, Johansson PeterDepartment of Internal Medicine, Uddevalla Hospital, Uddevalla, SwedenBackground: Once a month, patients with multiple myeloma received an infusion of bisphosphonates, principally to reduce osteoclastic bone resorption. Recommended infusion time for pamidronate is 2 hours in the US and 4 hours in Europe because of its potential nephrotoxicity. From 2003, a 90 mg infusion of pamidronate was provided over 1 hour to patients with no pre-existing renal impairment, in the Daily Care Unit at Uddevalla Hospital.Method: Retrospective analysis of the renal deterioration, serum calcium, and adverse effects in patients with multiple myeloma treated with 1-hour pamidronate 90 mg infusion from January 2003 to April 2007.Results: Seventy-nine patients provided valuable data. A total number of 846 infusions were given and the median number of infusion to each patient was 11. Significant creatinine elevation was seen in 7 patients (8.9%, after 19 infusions (2.2%. Renal deterioration occurred in 5 of these 7 patients, which was related to progress of the myeloma or opportunistic infections. Prevalence of infusion-related events was 0.8% and the mean total S-Ca was 0.05 mmol/L lower than the baseline.Conclusion: Few events of renal deterioration, hypocalcemia, or other adverse effects resulted from a 1-hour pamidronate 90 mg infusion for multiple myeloma patients with no pre-existing renal impairment.Keywords: bisphosphonates, pamidronate, multiple myeloma, infusion time

Septal co-infusions of glucose with the benzodiazepine agonist chlordiazepoxide impair memory, but co-infusions of glucose with the opiate morphine do not.

Science.gov (United States)

Krebs-Kraft, Desiree L; Parent, Marise B

2010-03-30

We have found repeatedly that medial septal (MS) infusions of glucose impair memory when co-infused with the gamma-amino butyric acid (GABA) agonist muscimol. The present experiments sought to determine whether the memory-impairing effects of this concentration of glucose would generalize to another GABA(A) receptor agonist and to an agonist from another neurotransmitter system that is known to impair memory. Specifically, we determined whether the dose of glucose that produces memory deficits when combined with muscimol in the MS would also impair memory when co-infused with the GABA(A) receptor modulator chlordiazepoxide (CDP) or the opiate morphine. Male Sprague-Dawley rats were given MS co-infusions and then 15 min later tested for spontaneous alternation or given shock avoidance training (retention tested 48 h later). The results showed that MS infusions of the higher dose of glucose with morphine did not produce memory deficits, whereas, the performance of rats given MS co-infusions of CDP with glucose was impaired. These findings suggest that the memory-impairing effects of brain glucose administration may involve an interaction with the GABA(A) receptor. (c) 2009 Elsevier Inc. All rights reserved.

75 FR 21641 - Infusion Pumps; Public Meeting; Request for Comments

Science.gov (United States)

2010-04-26

...] Infusion Pumps; Public Meeting; Request for Comments AGENCY: Food and Drug Administration, HHS. ACTION... announcing a public meeting regarding external infusion pumps. The purpose of the meeting is to inform the public about current problems associated with external infusion pump use, to help the agency identify...

Using higher doses to compensate for tubing residuals in extended-infusion piperacillin-tazobactam.

Science.gov (United States)

Lam, Wendy J; Bhowmick, Tanaya; Gross, Alan; Vanschooneveld, Trevor C; Weinstein, Melvin P

2013-06-01

To mathematically assess drug losses due to infusion line residuals and evaluate methods to compensate for drug loss due to residual volumes in intravenous pump tubing. Literature was accessed through Ovid MEDLINE (1996-February 2013), using combinations of the search terms tubing residuals, residual volume, residual medication, intravenous infusions, intravenous injections, piperacillin, piperacillin-tazobactam, β-lactams, equipment design, infusion pumps, extended infusion, extended administration, and prolonged infusion. In addition, select reference citations from publications identified were reviewed. All articles that involved extended-infusion piperacillin-tazobactam implementation strategies were included in the review. Infusion pump characteristics and tubing residuals can affect extended-infusion piperacillin-tazobactam dosing strategies. Two studies addressing tubing residuals were identified. Both studies recommended increasing infusion volumes to compensate for tubing residuals. One study also recommended decreasing infusion-line dead space by using alternative infusion pump systems. Study calculations suggest that higher doses of piperacillin-tazobactam may be used to account for medication left in tubing residuals if alternative infusion pump systems cannot be obtained, and increased infusion volumes are not an option. Extended-infusion piperacillin-tazobactam has been used as a method of maximizing pharmacodynamic target attainment. Use of higher doses of piperacillin-tazobactam may be a reasonable method to compensate for drug loss due to residual volumes in large-bore intravenous pump tubing.

Superselective intraarterial infusion therapy for head and neck carcinomas

International Nuclear Information System (INIS)

Nakatani, Hiroaki; Sawada, Shoichi; Takeda, Taizo

2004-01-01

We report the results of superselective intraarterial cisplatin (CDDP) infusion therapy combined with irradiation for 23 patients, mainly advanced head and neck carcinoma. All patients received intraarterial CDDP infusions with intravenous sodium thiosulfate (STS) neutralization. CDDP infusion was performed by the Seldinger's technique in 16 patients and by the implanted intraarterial reservoir system in 7 patients. STS was also infused by the reservoir system implanted at the forearm in most patients. An overall response was observed in 21 of the 23 (91.3%) patients. Complete and partial responses were achieved in 16 (69.6%) and 5 (21.7%) patients, respectively. There were no patients with worse than grade III complications. We concluded that superselective intraarterial infusion therapy with a high dose of CDDP and STS was very effective for the management of advanced head and neck carcinomas and we recommend the implantable reservoir system for both CDDP and STS administration as an easy and low-invasive method. (author)

The cognitive processing of the allomorphy in Serbian

Directory of Open Access Journals (Sweden)

Jovanović Tamara

2008-01-01

Full Text Available In this work, we explored cognitive status of suffix allomorphy of the masculine nouns in instrumental singular in Serbian language (eg. mišom-mišem; pužom-pužem. Allomorphy represents distinct variations in form of the morpheme which does not influence it’s function and meaning (cf. Lyons, 1968. Despite it’s frequent appearance in speech and language production, it has rarely been a subject of psycholinguistic explorations. First goal of this research was to determine whether the cognitive processing of allomorphic nouns has it’s specificities and second goal was to create the base for making and testing hypothesis regarding morphological and/or phonological factors that influence suffix alternation in forming of instrumental singular of masculine nouns. We conducted visual lexical decision experiment and applied a questionnaire created for the needs of investigating allomorphy in language production. Results showed that at least two processes influence cognitive processing of masculine nouns in instrumental singular: (a certain morpho-phonological restrictions that influence appearance of the suffix-em, and (b allomorphy - variations in suffix in instrumental singular. In addition, the findings indicate that allomorphy could be the consequence of the tendency to use more frequent suffix (-om, that eases the processing, and blocks the influence of the morpho-phonological restrictions.

Infusion pressure and pain during microneedle injection into skin of human subjects

Science.gov (United States)

Gupta, Jyoti; Park, Sohyun; Bondy, Brian; Felner, Eric I.; Prausnitz, Mark R.

2011-01-01

Infusion into skin using hollow microneedles offers an attractive alternative to hypodermic needle injections. However, the fluid mechanics and pain associated with injection into skin using a microneedle have not been studied in detail before. Here, we report on the effect of microneedle insertion depth into skin, partial needle retraction, fluid infusion flow rate and the co-administration of hyaluronidase on infusion pressure during microneedle-based saline infusion, as well as on associated pain in human subjects. Infusion of up to a few hundred microliters of fluid required pressures of a few hundred mmHg, caused little to no pain, and showed weak dependence on infusion parameters. Infusion of larger volumes up to 1 mL required pressures up to a few thousand mmHg, but still usually caused little pain. In general, injection of larger volumes of fluid required larger pressures and application of larger pressures cause more pain, although other experimental parameters also played a significant role. Among the intradermal microneedle groups, microneedle length had little effect; microneedle retraction lowered infusion pressure but increased pain; lower flow rate reduced infusion pressure and kept pain low; and use of hyaluronidase also lowered infusion pressure and kept pain low. We conclude that microneedles offer a simple method to infuse fluid into the skin that can be carried out with little to no pain. PMID:21684001

Performance management system in sale and distribution: A case of Serbian company

Directory of Open Access Journals (Sweden)

Aleksandar Jankulović

2013-09-01

Full Text Available Background: Performance management system (PMS is the process of quantifying action which leads to organizational efficiency, competitiveness and growth. Performance measurement is the vital element of quality management system (QMS. Innovative companies have a strong culture, clear sense of mission and purpose, a well thought out strategy and business philosophy of continuous improvement, driven by QMS. Implementation of QMS ISO9001 standards has encouraged many organizations to develop and implement performance management system. Statement of quality objectives and Measurement, analysis and improvement as a part of QMS which leads to continual improvement is a vital part of success of company. Therefore PMS influence on sale, distribution and logistics companies with a complex processes and great number of subjects in supply chain are of great importance for their success. Methods: In our research we analyse measures and measurement approaches and frameworks that exist in logistic management and based on that we present results from one SME from eastern European country. We use case study research and therefore we conduct interviews with managers, employees and QMS/PMS implementation staff in sale and distribution company. Results: The aim of this study was to estimate the value of various metrics of the evaluation of QMS implementation. The study was based on case study in one Serbian sale and distribution company specifically in measurement part and metrics that are essential for their business and to compare them with approaches existed in literature. We reveal some obstacles in collecting data for measurement and benchmarking in Serbian market. Different metrics for efficient management of company are implemented in this company based on sales results and customer satisfaction.  Conclusion:  The importance of the research is in the fact that implementation of QMS reveal the need for PMS implementation and therefore results in certain

Psychometric properties of the Serbian version of the negative acts questionnaire - revised

Directory of Open Access Journals (Sweden)

Vukelić Milica

2015-01-01

Full Text Available The Negative Acts Questionnaire-Revised (NAQ-R, together with its earlier version, The Negative Acts Questionnaire (NAQ, is one of the most utilized instruments for exploring workplace bullying, both in applied and scientific research. Contrary to its widespread use, there are a few published NAQ-R validation studies. In this paper we wanted to support developing grounds for future cultural analysis, comparison and development of the NAQ-R which was created as an instrument primarily for measuring workplace bullying in Anglo- American cultural settings. The aim of this study was to analyze the psychometric properties of the Serbian translation of the Negative Acts Questionnaire-Revised (NAQ-R by exploring its factor structure, internal consistency and criterion validity. The sample comprised 1710 employees from both private and public sector in Serbia. Principal component analysis revealed one component that explained almost 60% of the total variance. The Confirmatory factor analysis was carried out in order to test the one, two and three factor solutions suggested by the authors of the NAQ. The results of CFA confirmed all three solutions, but only fairly, as some of the fit indicators did not reach the expected values. Reliability analysis showed excellent internal consistency of the NAQ-R (Cronbach’s alpha=0.96. The significant correlations of the NAQ-R with job and organization related measures, and subjective health and well-being measures provided evidence of its construct validity. Higher correlations of the NAQ-R with a set of work related behaviors than the correlations with health related measures were in accordance with the nature of the phenomenon that is primarily focused on work-disabling behaviors. The results of this study showed acceptable psychometric properties of the Serbian translation of the NAQ-R. Obtained findings indicate that the future development of the Negative Acts Questionnaire-Revised could follow two streams

Captured ‘Realities’ of Human Trafficking: Analysis of photographs illustrating stories on trafficking into the sex industry in Serbian media

Directory of Open Access Journals (Sweden)

Elena Krsmanovic

2016-09-01

Full Text Available Past research has looked at how the media frames human trafficking, but has seldom included analysis of visual representations. To bridge this gap, this paper scrutinises stereotypical representations of persons trafficked into the sex industry in photographs published in Serbian online media from 2011 to 2014. To uncover characteristics of dominant tropes in this sample, a method of semiotic analysis is applied. The analysis argues that images are dominated by portrayals of trafficked persons that fit into one of two frames: powerless victim or unworthy prostitute. Male figures are rarely presented in these photographs, but when present, they are shown to hurt or control the women depicted alongside them. Chains, padlocks, barcodes, whip marks, and other symbols associated with slavery are present to a lesser extent. However, they testify to the tendency to link human trafficking to slavery and to use the moral potential of the anti-slavery rhetoric. Photographs are too easily seen as authentic, factual transcripts of reality. This paper suggests that these images tell us more about societal fear of insecurity, ideas about gender, erotic obsessions and morality than about human trafficking itself. It also argues that the meaning of trafficking is shaped by the deeply embedded codes of patriarchy and hidden misogyny present in Serbian society.

Associations between bolus infusion of hydrocortisone, glycemic variability and insulin infusion rate variability in critically Ill patients under moderate glycemic control

NARCIS (Netherlands)

van Hooijdonk, Roosmarijn T. M.; Binnekade, Jan M.; Bos, Lieuwe D. J.; Horn, Janneke; Juffermans, Nicole P.; Abu-Hanna, Ameen; Schultz, Marcus J.

2015-01-01

We retrospectively studied associations between bolus infusion of hydrocortisone and variability of the blood glucose level and changes in insulin rates in intensive care unit (ICU) patients. 'Glycemic variability' and 'insulin infusion rate variability' were calculated from and expressed as the

Prepreg and infusion processes for modern wind turbine blades

Energy Technology Data Exchange (ETDEWEB)

Shennan, C. [Hexcel, Cambridge (United Kingdom)

2013-09-01

The different elements of wind turbine blades have been analyzed for their main function, performance requirements and drivers. Key drivers can be simplified to either performance or cost. The use of prepreg and infusion to make these blade elements has then been compared and shows, from a comparison of test laminates, that prepreg typically delivers higher mechanical performance on both glass and carbon. One of the main process differences, cure temperature, has been overcome with the introduction of M79 which cures at 70 deg. - 80 deg. C. M79 combines this low cure temperature with a much lower reaction enthalpy allowing shorter cure cycles. This means that prepregs can now be cured in the same molds, at the same temperatures and with the same foam as used in a conventional infusion process. Although prepreg and infusion are usually used separately for making blade elements, they may also be used in combination: co-infused and co-cured using prepregs for the hard to infuse unidirectional load-carrying elements and infusion for the other elements. This can thus simplify the production process. The conclusion is that unidirectional prepregs are ideally suited for the performance driven parts of the blade such as in load carrying elements. (Author)

Virtual existence in contemporary Serbian novel

Directory of Open Access Journals (Sweden)

Gordić-Petković Vladislava S.

2017-01-01

Full Text Available The paper sets out to explore the perspectives and strategies of virtual existence in contemporary Serbian novel in order to illustrate radical changes in the concept of reality and writers' concern with the fidelity to experience. A new surge of the so-called digital realism emerges simultaneously with the increase of awareness that the line between our digital selves and our real-world selves has become blurred and difficult to explain, while new technologies are required to go beyond what our human senses can encompass and deliver. The fictional realism of the digital age will also commit itself to young or middle-aged individuals that passionately attempt to define their aims and objectives so that they could fit into a newly constructed and acquired concept of reality. This is the case with the protagonists in the novels by Ivančica Đerić, Tamara Jecić and Aleksandar Ilić, all of them questioning both their offline and online identities. Their everyday life in a postmillennial world includes many intersecting empirical and virtual realities: love, career and sex take place in a dimension which ignores geography and physical distance and ultimately alters the concepts of time and space, as well the concepts of privacy and intimacy. The paper intends to examine the ways new digital technologies contribute to representations of reality in the novels of both accomplished and aspiring authors whose novels deal with ways of life amid social networks. The novels we analyzed show that the distinction between the virtual and the real world narrows, as the narratives range from intimate confession in letters and journals to tweets, notes and statuses, introducing verbal and structural experimental practices which involve shifting points of view.

Use of propofol infusion in alcohol withdrawal-induced refractory delirium tremens

DEFF Research Database (Denmark)

Lorentzen, Kristian; Lauritsen, Anne Øberg; Bendtsen, Asger Ole

2014-01-01

in case reports. We aimed to evaluate the treatment of delirium tremens with propofol infusion for 48 h. MATERIAL AND METHODS: This study was a single-centre retrospective cohort analysis of 15 patient journals covering the period from May 2012 to September 2013. RESULTS: Five women and ten men were...... and mechanically ventilated in the intensive care unit. The mean propofol infusion rate was 4.22 mg/kg/h. Thirteen patients received supplemental infusion of opioids, whereas seven required concomitant vasopressor infusion. Once propofol infusion was discontinued after 48 h, 12 patients had a long awakening...

Advancing medication infusion safety through the clinical integration of technology.

Science.gov (United States)

Gerhart, Donald; O'Shea, Kristen; Muller, Sharon

2013-01-01

Adverse drug events resulting from errors in prescribing or administering medications are preventable. Within a hospital system, numerous technologies are employed to address the common sources of medication error, including the use of electronic medical records, physician order entry, smart infusion pumps, and barcode medication administration systems. Infusion safety is inherently risky because of the high-risk medications administered and the lack of integration among the stand-alone systems in most institutions. Intravenous clinical integration (IVCI) is a technology that connects electronic medical records, physician order entry, smart infusion pumps, and barcode medication administration systems. It combines the safety features of an automatically programmed infusion pump (drug, concentration, infusion rate, and patient weight, all auto-programmed into the device) with software that provides visibility to real-time clinical infusion data. Our article describes the characteristics of IVCI at WellSpan Health and its impact on patient safety. The integrated infusion system has the capability of reducing medication errors, improving patient care, reducing in-facility costs, and supporting asset management. It can enhance continuous quality improvement efforts and efficiency of clinical work flow. After implementing IVCI, the institution realized a safer patient environment and a more streamlined work flow for pharmacy and nursing.

Attacks of the soccer teams participating in the champions league and the Serbian super liga

Directory of Open Access Journals (Sweden)

Janković Aleksandar

2016-01-01

Full Text Available The area of tactics in soccer game is of particular importance for modern soccer development. The analysis and improvement of spatio-temporal indicators as well as the game principles related to tactics may be crucial to the achievement of competitive results. This study is aimed at comparing tactical manifestations of the teams competing in the top quality European club competition, the Champions League, and the best Serbian soccer championship by analyzing competitive activity. The results of the conducted research were obtained by observing an overall of 20 randomly selected matches, 10 of the Champions League (CL and 10 of the Serbian Super Liga (SSL, which is a sufficient number of matches for making conclusions about the competitions respectively. In the previously designed observing protocol, using a method of notation, we analyzed all the attacks completed by shooting at the opponent's goal. The structure of successfully realized attacks was assessed on the basis of: accuracy, types of realized offensive actions; area of starting the action, manner of realization of passes completed (assists and distance from the goal from which a shot on goal was executed. The study showed that there are certain common characteristics, but also there are differences in the structure of successfully realized attacks between the two analyzed competitions. The teams of the CL competition had significantly greater number of effective attacks per match (p = 0. 006, they realized their offensive activities with slightly greater number of players (p = 0.002 and number of passes (p = 0.000, whereas there are no significant differences in the area of starting successful attacks, the manner of realization of assists and distance from which shots on goal were executed. The study results may define certain guidelines in training technology when preparing the teams of the SSL competition for taking part in the European soccer cups.

Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults.

Science.gov (United States)

Tampakakis, Emmanouil; Tabit, Corey E; Holbrook, Monika; Linder, Erika A; Berk, Brittany D; Frame, Alissa A; Bretón-Romero, Rosa; Fetterman, Jessica L; Gokce, Noyan; Vita, Joseph A; Hamburg, Naomi M

2016-01-11

Endoplasmic reticulum (ER) stress and the subsequent unfolded protein response may initially be protective, but when prolonged, have been implicated in atherogenesis in diabetic conditions. Triglycerides and free fatty acids (FFAs) are elevated in patients with diabetes and may contribute to ER stress. We sought to evaluate the effect of acute FFA elevation on ER stress in endothelial and circulating white cells. Twenty-one healthy subjects were treated with intralipid (20%; 45 mL/h) plus heparin (12 U/kg/h) infusion for 5 hours. Along with increased triglyceride and FFA levels, intralipid/heparin infusion reduced the calf reactive hyperemic response without a change in conduit artery flow-mediated dilation consistent with microvascular dysfunction. To investigate the short-term effects of elevated triglycerides and FFA, we measured markers of ER stress in peripheral blood mononuclear cells (PBMCs) and vascular endothelial cells (VECs). In VECs, activating transcription factor 6 (ATF6) and phospho-inositol requiring kinase 1 (pIRE1) proteins were elevated after infusion (both P<0.05). In PBMCs, ATF6 and spliced X-box-binding protein 1 (XBP-1) gene expression increased by 2.0- and 2.5-fold, respectively (both P<0.05), whereas CHOP and GADD34 decreased by ≈67% and 74%, respectively (both P<0.01). ATF6 and pIRE1 protein levels also increased (both P<0.05), and confocal microscopy revealed the nuclear localization of ATF6 after infusion, suggesting activation. Along with microvascular dysfunction, intralipid infusion induced an early protective ER stress response evidenced by activation of ATF6 and IRE1 in both leukocytes and endothelial cells. Our results suggest a potential link between metabolic disturbances and ER stress that may be relevant to vascular disease. © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

Mixing in the human carotid artery during carotid drug infusion studied with PET

International Nuclear Information System (INIS)

Junck, L.; Koeppe, R.A.; Greenberg, H.S.

1989-01-01

The safety and efficacy of drug infusion into the carotid artery require adequate mixing of the infused solution with carotid blood. Using positron emission tomography (PET), we studied the mixing of solutions infused into the human carotid artery in seven patients by analyzing the distribution of [15O]H2O infused into the carotid artery and by vein. At four infusion rates ranging from 0.5 to 10 ml/min, the variability in distribution averaged 16.5-17.8% among the pixels in a large volume of interest, without dependence on the infusion rate. The overall correlation between [15O]H2O influx with arterial infusion and [15O]H2O influx with venous injection was 0.78-0.82 at the four infusion rates, with no trend toward higher correlations at the faster infusion rates. The distribution into the anterior, middle, and posterior cerebral artery territories differed from distribution throughout the entire carotid territory by an average of 6.2-9.6% at the four infusion rates, with no trend toward smaller differences at the faster infusion rates. Infusions performed into a vinyl tube simulating the carotid artery indicated that at 0.5 ml/min, the velocity of fluid exiting the catheter makes no apparent contribution to mixing. We conclude that with infusions at the carotid bifurcation, mixing in the human carotid artery is complete or nearly complete over a wide range of infusion rates. The mixing appears to result from the patterns of blood flow within the artery, and not from jet effects at the catheter tip

Brain SPECT by intraarterial infusion of 99mTc-HMPAO for assessing the cerebral distribution of carotid artery infusions in patient with brain tumor

International Nuclear Information System (INIS)

Kosuda, Shigeru; Kusano, Shoichi; Aoki, Shigeki

1993-01-01

In order to assess the cerebral distribution of intracarotid chemotherapy, 17 postoperative patients with brain tumor underwent brain SPECT obtrained by intraarterial infusion of 18.5 MBq of 99m Tc-d,l,-hexamethylpropyleneamine oxime ( 99m Tc-HMPAO). Injection methods were continuous (5.0 ml/min) or pulsatile infusion with supra- or infraophthalmic catheterization. The findings obtained by brain SPECT were frequently different from those of angiography and/or DSA. In supraophthalmic catheterization with continuous infusion, only 2 of 10 studies (20%) had homogeneous distribution and 5 of them (50%) had maldistribution of 99m Tc-HMPAO which appears in association with laminar flow effect. The remaining 3 studies showed localized distribution (two: tumor localization, one: healthy brain localization). On the other hand, all of 5 studies with pulsatile infusion had homogeneous distribution of 99m Tc-HMPAO. In infraophthalmic catheterization, all but one of 5 studies had homogeneous distribution with continuous infusion. These results suggest that pulsatile infusion may be effective in eliminating maldistribution of 99m Tc-HMPAO in supraophthalmic catheterization. In conclusion, we are convinced that 99m Tc-HMPAO is a useful intraarterial agent for assessing cerebral distribution of intracarotid chemotherpay. (author)

The Tolerability and Efficacy of Rapid Infliximab Infusions in Patients with Inflammatory Bowel Disease.

Science.gov (United States)

Qazi, Taha; Shah, Bhavesh; El-Dib, Mohammed; Farraye, Francis A

2016-02-01

Few studies have assessed the loss of efficacy or patient and caregiver satisfaction with rapid infliximab infusions. The aim of this study is to assess the tolerability, loss of efficacy and to describe the impact on resource utilization and patient satisfaction in rapid infliximab infusions. Subjects with inflammatory bowel disease receiving rapid infliximab infusions were included in the study. Subjects received maintenance infusions from June 2011 to June 2013. Incidence of adverse reactions and the total number of rapid infliximab infusions were recorded. Efficacy was compared to published studies evaluating the long-term efficacy of infliximab infusions. Patient satisfaction was addressed through a survey following the implementation of the rapid infusion protocol. Seventy-five subjects with IBD were included in the study. Five hundred and twenty-two rapid infliximab infusions were provided to patients. There were no acute or delayed infusion reactions. Ten subjects (13 %) required either a dose escalation or interval adjustment between infliximab infusions. A majority of patients reported increased satisfaction with 1-h infliximab infusions, and 97 % of surveyed patients opted to continue rapid infusions. The rapid infliximab infusion protocol increased infusion unit efficiency by increasing capacity by 15 %. Cost savings in the elimination of nursing time translated to approximately $108,150 savings at our institution. Rapid infliximab infusions do not appear to increase the risk of loss of response compared to historical studies of long-term infliximab efficiency. A rapid infliximab infusion protocol improved efficiency in our infusion unit and increased patient and nursing satisfaction.

Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia.

Science.gov (United States)

Comelon, M; Raeder, J; Stubhaug, A; Nielsen, C S; Draegni, T; Lenz, H

2016-04-01

The aim of this study was to examine if gradual withdrawal of remifentanil infusion prevented opioid-induced hyperalgesia (OIH) as opposed to abrupt withdrawal. OIH duration was also evaluated. Nineteen volunteers were enrolled in this randomized, double-blinded, placebo-controlled, crossover study. All went through three sessions: abrupt or gradual withdrawal of remifentanil infusion and placebo. Remifentanil was administered at 2.5 ng ml(-1) for 30 min before abrupt withdrawal or gradual withdrawal by 0.6 ng ml(-1) every five min. Pain was assessed at baseline, during infusion, 45-50 min and 105-110 min after end of infusions using the heat pain test (HPT) and the cold pressor test (CPT). The HPT 45 min after infusion indicated OIH development in the abrupt withdrawal session with higher pain scores compared with the gradual withdrawal and placebo sessions (both Pwithdrawal compared with placebo (P=0.93). In the CPT 50 min after end of infusion there was OIH in both remifentanil sessions compared with placebo (gradual P=0.01, abrupt Pwithdrawal of remifentanil infusion in the HPT. After abrupt withdrawal OIH was present in the HPT. In the CPT there was OIH after both gradual and abrupt withdrawal of infusion. The duration of OIH was less than 105 min for both pain modalities. NCT 01702389. EudraCT number 2011-002734-39. © The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Psychometric evaluation and validation of the Serbian version of “Reading the mind in the eyes” test

Directory of Open Access Journals (Sweden)

Đorđević Jelena

2017-01-01

Full Text Available “Reading the Mind in the Eyes” test (RMET is one of the most popular and widely used measures of individual differences in Theory of Mind (ToM capabilities. Despite demonstrating good validity in differentiating various clinical groups exhibiting ToM deficits from unimpaired controls, previous studies raised the question of the RMET’s homogeneity, latent structure, and reliability. The aim of this study is to provide evidence on psychometric properties, latent structure, and validity of the newly adapted Serbian version of the RMET. In total, 260 participants (61.9% females took part in the study. The sample consisted of both unimpaired controls (76.5%, and a clinical group of participants that are believed to demonstrate ToM deficits (23.5%, namely, persons diagnosed with schizophrenia and bipolar disorder (54.1% females. RMET has demonstrated fair psychometric properties (KMO = .723; α = .747; H1 = .076; H5 = .465, successfully differentiating between clinical group and control [F (1,254 = 26.175, p <.001, η2 p = .093], while typical gender differences in performance were found only in control group. Tests of several models based on the previous literature revealed that the affect-specific factors underlying performance on RMET demonstrate poor fit. The best fitting model obtained included reduced scale with a single-factor underlying the test’s performance (TLI = .953, CFI = .958, RMSEA = .020. Based on the fit parameters we propose 18-item short-form of the Serbian version of RMET (KMO = .797; α = .728; H1 = .129; H5 = .677 for economic, reliable and valid measurement of ToM abilities.

RA Research nuclear reactor - Annual report 1987

International Nuclear Information System (INIS)

1987-12-01

Annual report concerning the project 'RA research nuclear reactor' for 1987, financed by the Serbian ministry of science is divided into two parts. First part is concerned with RA reactor operation and maintenance, which is the task of the Division for reactor engineering of the Institute for multidisciplinary studies and RA reactor engineering. Second part deals with radiation protection activities at the RA reactor which is the responsibility of the Institute for radiation protection. Scientific council of the Institute for multidisciplinary studies and RA reactor engineering has stated that this report describes adequately the activity and tasks fulfilled at the RA reactor in 1989. The scope and the quality of the work done were considered successful both concerning the maintenance and reconstruction, as well as radiation protection activities [sr

Research nuclear reactor RA - Annual Report 1989

International Nuclear Information System (INIS)

Sotic, O.

1989-12-01

Annual report concerning the project 'RA research nuclear reactor' for 1989, financed by the Serbian ministry of science is divided into two parts. First part is concerned with RA reactor operation and maintenance, which is the task of the Division for reactor engineering of the Institute for multidisciplinary studies and RA reactor engineering. Second part deals with radiation protection activities at the RA reactor which is the responsibility of the Institute for radiation protection. Scientific council of the Institute for multidisciplinary studies and RA reactor engineering has stated that this report describes adequately the activity and tasks fulfilled at the RA reactor in 1989. The scope and the quality of the work done were considered successful both concerning the maintenance and reconstruction, as well as radiation protection activities [sr

Symptomatic Tarlov Cysts: Surgical Treatment by Subcutaneous Infusion Port.

Science.gov (United States)

Huang, Ying; Zhu, Tong; Lin, Hongyi; Li, Jing; Zeng, Tao; Lin, Jian

2018-05-01

The treatment of Tarlov cysts is challenging and difficult. The objective of our study was to describe the security and efficacy of the subcutaneous infusion port for drainage of symptomatic Tarlov cysts. The authors executed a retrospective review of data from 5 symptomatic Tarlov cysts patients who were treated using a subcutaneous infusion port from June 2014 to July 2017. Numerical Rating Scale scores and the Japanese Orthopedic Association scores of back pain were analyzed. Complications and adverse effects on postoperative days 1, 7, 14, and 28 were also analyzed. The mean follow-up was 12.6 months. Five adults (3 females and 2 males) who had been symptomatic received a subcutaneous infusion port. After treatment, all patients experienced pain relief and pain alleviation lasted from 1 day to 3 years without complications and adverse effects. A subcutaneous infusion port is a useful treatment option for symptomatic Tarlov cysts. When the patients' symptoms returned and the cysts repressurized, we quickly and simply drained the cysts by using the infusion port. Copyright © 2018 Elsevier Inc. All rights reserved.

Vacuum infusion manufacturing and experimental characterization of Kevlar/epoxy composites

International Nuclear Information System (INIS)

Ricciardi, M. R.; Giordano, M.; Antonucci, V.; Langella, A.; Nele, L.

2014-01-01

Epoxy/Kevlar composites have been manufactured by conventional Vacuum Infusion process and the Pulse Infusion technique. Pulse Infusion allows to control the pressure of the vacuum bag on the dry fiber reinforcement by using a proper designed pressure distributor that induces a pulsed transverse action and promotes the through thickness resin flow. The realized composite panel have been mechanically characterized by performing tensile and short beam shear tests according with the ASTM D3039 and ASTM D2344/D 2344M standard respectively in order to investigate the effect of Pulse Infusion on the tensile strength and ILSS

Vacuum infusion manufacturing and experimental characterization of Kevlar/epoxy composites

Science.gov (United States)

Ricciardi, M. R.; Giordano, M.; Langella, A.; Nele, L.; Antonucci, V.

2014-05-01

Epoxy/Kevlar composites have been manufactured by conventional Vacuum Infusion process and the Pulse Infusion technique. Pulse Infusion allows to control the pressure of the vacuum bag on the dry fiber reinforcement by using a proper designed pressure distributor that induces a pulsed transverse action and promotes the through thickness resin flow. The realized composite panel have been mechanically characterized by performing tensile and short beam shear tests according with the ASTM D3039 and ASTM D2344/D 2344M standard respectively in order to investigate the effect of Pulse Infusion on the tensile strength and ILSS.

Rapid infusion with rituximab: short term safety in systemic autoimmune diseases

DEFF Research Database (Denmark)

Larsen, Janni Lisander; Jacobsen, Soren

2013-01-01

To describe the incidence, types and severity of adverse events, related to an accelerated regime of rituximab infusion in patients with various autoimmune diseases. Fifty-four patients with systemic autoimmune disease, to be treated with 1,000 mg of rituximab twice 2 weeks apart, participated. Pre......-medication (oral prednisolone, anti-histamine and paracetamol) was administered 1-4 h before infusion start. The first infusion was administered over a period of 195 min. The second infusion over a period of 90 min. Any adverse events were classified using the Clinical Trials Classification of Adverse Events...... (CTCAE) v. 3.0. Ten patients (18.5%) experienced at least one infusion-related reaction (IRR) ever. The first infusion was associated with reactions in 4 CTCAE categories of which rhinitis were the most frequent. The CTCAE severity grading showed six patients (11.1%) had a grade 1 reaction. One patient...

Hospital management training and improvement in managerial skills: Serbian experience.

Science.gov (United States)

Supic, Zorica Terzic; Bjegovic, Vesna; Marinkovic, Jelena; Milicevic, Milena Santric; Vasic, Vladimir

2010-06-01

The purpose of this study was to analyze the improvement of managerial skills of hospitals' top managers after a specific management training programme, and to explore possible predictors and relations. The study was conducted during the years 2006 and 2007 with cohort of 107 managers from 20 Serbian general hospitals. The managers self-assessed the improvement in their managerial skills before and after the training programme. After the training programme, all managers' skills had improved. The biggest improvement was in the following skills: organizing daily activities, motivating and guiding others, supervising the work of others, group discussion, and situation analysis. The least improved were: applying creative techniques, working well with peers, professional self-development, written communication, and operational planning. Identified predictors of improvement were: shorter years of managerial experience, type of manager, type of profession, and recognizing the importance of the managerial skills in oral communication, evidence-based decision making, and supervising the work of others. Specific training programme related to strategic management can increase managerial competencies, which are an important source of competitive advantage for organizations. Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

Infusion of iloprost without a peristaltic pump: Safety and tolerability

Directory of Open Access Journals (Sweden)

Paola Faggioli

2013-04-01

Full Text Available Introduction: Iloprost is a potent prostacyclin (PGI2 analogue that is effective in the treatment of peripheral arterial disease, vasculitis, pulmonary hypertension, and secondary Raynaud’s phenomenon. Intravenous infusions are generally administered with the aid of a peristaltic pump to reduce the risk of adverse reactions caused by unintentional increases in the infusion rate. This increases the cost of care in terms of equipment and personnel and may limit the use of this drug. Materials and methods: We retrospectively analyzed 18,432 iloprost infusions administered between 1999 and 2009 to 272 patients with systemic sclerosis (n = 253 and 19 with peripheral arterial disease (n = 19. All infusions were administered in the day hospital over 6 h with a normal IV set-up with a roller flow regulator. Flow rates were set to deliver iloprost at 1-2 ng/kg/min. Rates were verified by direct drop counts during the first 15-20 minutes of the infusion and at each subsequent check. Results: There were no adverse events that were fatal, life-threatening, or associated with prolongation of hospitalization and very few events requiring intensive care or continuous monitoring. The latter included 4 cases of tachycardia/arrhythmia (extrasystoles in most cases, 3 cases of hypotension (systolic pressure < 80 mmHg, and 2 cases of hypertension (BP > 170/100 mmHg. All other adverse reactions were mild, reversible, and similar to those seen with iloprost infusion with peristaltic pump. Only one patient had to be switched to another prostanoid (due to intolerance. Discussion: Iloprost infusion administered with a normal IV flow regulator appears to be as safe, well tolerated, and effective as traditional infusion with a peristaltic pump.

Natriuretic peptide infusion reduces myocardial injury during acute ischemia/reperfusion

DEFF Research Database (Denmark)

Kousholt, Birgitte S.; Larsen, Jens Kjærgaard Rolighed; Bisgaard, Line Stattau

2012-01-01

Aim: The aim of this study was to determine whether a natriuretic peptide infusion during reperfusion can reduce cardiomyocyte ischemia–reperfusion damage. Materials and methods: The effect of B-type natriuretic peptide (BNP) activity was assessed in vitro and in vivo: the cellular effect...... in apoptotic changes in the BNP-stimulated cells. Pigs tolerated the BNP and CD-NP (a CNP analogue) infusion well, with a decrease in systemic blood pressure (~15 mmHg) and increased diuresis compared with the controls. Left ventricular pressure decreased in the pigs that received BNP infusion compared...... with controls (P=0.02). A similar trend was observed in the pigs that received CD-NP infusion, although this was not significant (P=0.3). BNP and CD-NP infusion in pigs reduced total cardiac troponin T release by 46 and 40%, respectively (P=0.0015 and 0.0019), and were associated with improved RNA integrity...

Natriuretic peptide infusion reduces myocardial injury during acute ischemia/reperfusion

DEFF Research Database (Denmark)

Kousholt, Birgitte S.; Larsen, Jens Kjærgaard Rolighed; Bisgaard, Line Stattau

2012-01-01

Aim: The aim of this study was to determine whether a natriuretic peptide infusion during reperfusion can reduce cardiomyocyte ischemia–reperfusion damage. Materials and methods: The effect of B-type natriuretic peptide (BNP) activity was assessed in vitro and in vivo: the cellular effect...... in apoptotic changes in the BNP-stimulated cells. Pigs tolerated the BNP and CD-NP (a CNP analogue) infusion well, with a decrease in systemic blood pressure (∼15 mmHg) and increased diuresis compared with the controls. Left ventricular pressure decreased in the pigs that received BNP infusion compared...... with controls (P=0.02). A similar trend was observed in the pigs that received CD-NP infusion, although this was not significant (P=0.3). BNP and CD-NP infusion in pigs reduced total cardiac troponin T release by 46 and 40%, respectively (P=0.0015 and 0.0019), and were associated with improved RNA integrity...

Musical instruments depicted in medieval Serbian art under oriental and western influences

Directory of Open Access Journals (Sweden)

Pejović Roksanda

2005-01-01

Full Text Available Researching musical instruments on frescoes, miniatures, icons and sculptural decorations of mediaeval Serbian art, painted and sculptured in the manner of Byzantine art, we discover Oriental and Western influences. Musical instruments arriving from the Orient were unchanged for centuries and those from West Europe were mainly used in the Middle Ages or the Renaissance. Oriental and Western influences can be observed on instruments of all families-idiophones, membranophones, bowed and string instruments, as well as on aero phones. The same form of some crotales and cymbals can be found both in Oriental and Western art, the majority of membranophones are of Oriental origin, but the tambourine on Bodani frescoes originated in West Europe. Lyres and angular harps are close to Antique tradition. Some bowed instruments, psalteries, lutes, harps, short horns, business and shawms have Oriental patterns and other instruments of these families accepted Western shapes. There are, as well, same kinds of bowed instruments and S-trumpets peculiar for both continents.

Aluminum bioavailability from tea infusion.

Science.gov (United States)

Yokel, Robert A; Florence, Rebecca L

2008-12-01

The objective was to estimate oral Al bioavailability from tea infusion in the rat, using the tracer (26)Al. (26)Al citrate was injected into tea leaves. An infusion was prepared from the dried leaves and given intra-gastrically to rats which received concurrent intravenous (27)Al infusion. Oral Al bioavailability (F) was calculated from the area under the (26)Al, compared to (27)Al, serum concentration x time curves. Bioavailability from tea averaged 0.37%; not significantly different from water (F=0.3%), or basic sodium aluminum phosphate (SALP) in cheese (F=0.1-0.3%), but greater than acidic SALP in a biscuit (F=0.1%). Time to maximum serum (26)Al concentration was 1.25, 1.5, 8 and 4.8h, respectively. These results of oral Al bioavailability x daily consumption by the human suggest tea can provide a significant amount of the Al that reaches systemic circulation. This can allow distribution to its target organs of toxicity, the central nervous, skeletal and hematopoietic systems. Further testing of the hypothesis that Al contributes to Alzheimer's disease may be more warranted with studies focusing on total average daily food intake, including tea and other foods containing appreciable Al, than drinking water.

Tolerance to continuous intrathecal baclofen infusion can be reversed by pulsatile bolus infusion

NARCIS (Netherlands)

Heetla, H. W.; Staal, M. J.; van Laar, T.

Study design: Pilot study. Objective: To study the effect of pulsatile bolus infusion of intrathecal baclofen (ITB) on daily ITB dose, in patients showing dose increases, probably due to tolerance. Setting: Department of neurology and neurosurgery, University Medical Center Groningen, the

Educational Applications for Blind and Partially Sighted Pupils Based on Speech Technologies for Serbian

Science.gov (United States)

Lučić, Branko; Ostrogonac, Stevan; Vujnović Sedlar, Nataša; Sečujski, Milan

2015-01-01

The inclusion of persons with disabilities has always represented an important issue. Advancements within the field of computer science have enabled the development of different types of aids, which have significantly improved the quality of life of the disabled. However, for some disabilities, such as visual impairment, the purpose of these aids is to establish an alternative communication channel and thus overcome the user's disability. Speech technologies play the crucial role in this process. This paper presents the ongoing efforts to create a set of educational applications based on speech technologies for Serbian for the early stages of education of blind and partially sighted children. Two educational applications dealing with memory exercises and comprehension of geometrical shapes are presented, along with the initial tests results obtained from research including visually impaired pupils. PMID:26171422

Educational Applications for Blind and Partially Sighted Pupils Based on Speech Technologies for Serbian.

Science.gov (United States)

Lučić, Branko; Ostrogonac, Stevan; Vujnović Sedlar, Nataša; Sečujski, Milan

2015-01-01

The inclusion of persons with disabilities has always represented an important issue. Advancements within the field of computer science have enabled the development of different types of aids, which have significantly improved the quality of life of the disabled. However, for some disabilities, such as visual impairment, the purpose of these aids is to establish an alternative communication channel and thus overcome the user's disability. Speech technologies play the crucial role in this process. This paper presents the ongoing efforts to create a set of educational applications based on speech technologies for Serbian for the early stages of education of blind and partially sighted children. Two educational applications dealing with memory exercises and comprehension of geometrical shapes are presented, along with the initial tests results obtained from research including visually impaired pupils.

Intraarterial infusion chemotherapy for the treatment of metastatic liver cancer

International Nuclear Information System (INIS)

Arai, Yasuaki; Kido, Choichiro

1987-01-01

Some techniques of the most recent interventional radiology are very useful for the treatment of metastatic liver cancer and changing the style of hepatic infusion chemotherapy. This report shows our latest results and methods of hepatic infusion chemotherapy for metastatic liver cancer. 1. For the catheter placement, a new catheterization route via the left subclavian artery into the hepatic artery was developed and performed in 132 cases. Superselective catheterization succeeded in 123 cases (93.2 %). This procedure is less invasive than laparotomy and less troublesome than other percutaneous routes. 2. For useful infusion system, an implantable injection port ''Reservoir'' was developed and it was used in 87 cases. This method makes arterial infusion chemotherapy easy, and imploves their quality of life. 3. To acquire adequate drug delivery, arterial redistribution by steel coils was done, and 109 arteries in 80 cases were occluded. This method is very useful to make multiple hepatic artery single and it is important to avoid gasroduodenal complications. 4. Now, using these techniques, the phase II study of 5FU, ADM, MMC combined hepatic infusion in patients with non-resectable metastatic liver cancer is done. Up to this time, such a phase study on arterial infusion chemotherapy was difficult because of technical problems, but these new techniques make it possible. In conclusion, these new methods change the style and conception of hepatic infusion, and these make much progress on the treatment of patients with metastatic liver cancer. (author)

Planetary Science Technology Infusion Study: Findings and Recommendations Status

Science.gov (United States)

Anderson, David J.; Sandifer, Carl E., II; Sarver-Verhey, Timothy R.; Vento, Daniel M.; Zakrajsek, June F.

2014-01-01

The Planetary Science Division (PSD) within the National Aeronautics and Space Administrations (NASA) Science Mission Directorate (SMD) at NASA Headquarters sought to understand how to better realize a scientific return on spacecraft system technology investments currently being funded. In order to achieve this objective, a team at NASA Glenn Research Center was tasked with surveying the science and mission communities to collect their insight on technology infusion and additionally sought inputs from industry, universities, and other organizations involved with proposing for future PSD missions. This survey was undertaken by issuing a Request for Information (RFI) activity that requested input from the proposing community on present technology infusion efforts. The Technology Infusion Study was initiated in March 2013 with the release of the RFI request. The evaluation team compiled and assessed this input in order to provide PSD with recommendations on how to effectively infuse new spacecraft systems technologies that it develops into future competed missions enabling increased scientific discoveries, lower mission cost, or both. This team is comprised of personnel from the Radioisotope Power Systems (RPS) Program and the In-Space Propulsion Technology (ISPT) Program staff.The RFI survey covered two aspects of technology infusion: 1) General Insight, including: their assessment of barriers to technology infusion as related to infusion approach; technology readiness; information and documentation products; communication; integration considerations; interaction with technology development areas; cost-capped mission areas; risk considerations; system level impacts and implementation; and mission pull. 2) Specific technologies from the most recent PSD Announcements of Opportunities (AOs): The Advanced Stirling Radioisotope Generator (ASRG), aerocapture and aeroshell hardware technologies, the NASA Evolutionary Xenon Thruster (NEXT) ion propulsion system, and the

Continuous intravenous infusions of bromodeoxyuridine as a clinical radiosensitizer

International Nuclear Information System (INIS)

Kinsella, T.J.; Mitchell, J.B.; Russo, A.; Aiken, M.; Morstyn, G.; Hsu, S.M.; Rowland, J.; Glatstein, E.

1984-01-01

Twelve patients were treated with continuous intravenous (24-hour) infusions of bromodeoxyuridine (BUdR) at 650 or 1000 mg/m2/d for up to two weeks. Myelosuppression, especially thrombocytopenia, was the major systemic toxicity and limited the infusion period to nine to 14 days. However, bone marrow recovery occurred within seven to ten days, allowing for a second infusion in most patients. Local toxicity (within the radiation field) was minimal, with the exception of one of four patients, who underwent abdominal irradiation. Pharmacology studies revealed a steady-state arterial plasma level of 6 x 10(-7) mol/L and 1 x 10(-6) mol/L during infusion of 650 and 1000 mg/m2/d, respectively. In vivo BUdR uptake into normal bone marrow was evaluated in two patients by comparison of preinfusion and postinfusion in vitro radiation survival curves of marrow CFUc with enhancement ratios (D0-pre/D0-post) of 1.8 (with 650 mg/m2/d) and 2.5 (with 1000 mg/m2/d). In vivo BUdR incorporation into normal skin and tumor cells using an anti-BUdR monoclonal antibody and immunohistochemistry was demonstrated in biopsies from three patients revealing substantially less cellular incorporation into normal skin (less than 10%) compared with tumor (up to 50% to 70%). The authors conclude that local and systemic toxicity of continuous infusion of BUdR at 1000 mg/m2/d for approximately two weeks is tolerable. The observed normal tissue toxicity is comparable with previous clinical experience with intermittent (12 hours every day for two weeks) infusions of BUdR. Theoretically, a constant infusion should allow for greater incorporation of BUdR into cycling tumor cells and thus, for further enhancement of radiosensitization

21 CFR 880.2420 - Electronic monitor for gravity flow infusion systems.

Science.gov (United States)

2010-04-01

... and Personal Use Monitoring Devices § 880.2420 Electronic monitor for gravity flow infusion systems. (a) Identification. An electronic monitor for gravity flow infusion systems is a device used to... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electronic monitor for gravity flow infusion...

Questionnaire of social probability and potential consequences: Examination of reliability and validity on Serbian population

Directory of Open Access Journals (Sweden)

Ranđelović Kristina M.

2014-01-01

Full Text Available Prejudice in judgment has an important role in cognitive models of psychopathology. Every selective processing of emotionally relevant stimuli is called cognitive prejudice. One of the cognitive prejudices that is considered a key factor of socially - anxious disorder is prejudice in judgment. It is defined as a disposition to overestimate the probability of occurrence of negative social events in the near future, as well as potential consequences (agitation that might follow them. The perception of danger is essentially determined by a joined effect of subjective assessment of probability and agitation created by certain events. The researches have shown that socially-anxious individuals have a more expressive prejudice in judgment and that it can be reduced by applying certain psychotherapeutic and pharmacological treatments, which proves its relevance for the socially-anxious disorder. Considering the significance of the prejudice in judgment construct for the research and clinical practice and the lack of instruments that is operational in our country, the basic purpose of this paper is to check metric characteristics of the Serbian version of one of the most often mentioned and used questionnaires aimed at the assessment of this construct. It is the Questionnaire of social probability and potential consequences, which has two subscales: 1 to examine the reliability of the questionnaire on the sample of examinees from Serbia; 2 to examine the latent structure of the questionnaire and 3 to examine the construct of validity of the questionnaire by checking the correlations with other relevant constructs (personality traits, anxiety as a trait and fear of negative evaluation.The was adapted for Serbian language from English. The sample consists of 166 examinees, aged from 19 to 29 (AS = 21,73; SD = 1,43. The questionnaire for sensitivity to confirmation assessment was used to estimate personality traits, Anxiety as a trait was estimated by the

Systemic and regional hemodynamic effects of enalaprilat infusion in experimental normotensive sepsis

Directory of Open Access Journals (Sweden)

L. Rahal

Full Text Available Angiotensin-converting enzyme inhibitors have been shown to improve splanchnic perfusion in distinct shock states. We hypothesized that enalaprilat potentiates the benefits of early fluid resuscitation in severe experimental sepsis, particularly in the splanchnic region. Anesthetized and mechanically ventilated mongrel dogs received an intravenous infusion of live Escherichia coli over a period of 30 min. Thereafter, two interventions were performed: fluid infusion (normal saline, 32 mL/kg over 30 min and enalaprilat infusion (0.02 mg kg-1 min-1 for 60 min in randomized groups. The following groups were studied: controls (fluid infusion, N = 4, E1 (enalaprilat infusion followed by fluid infusion, N = 5 and E2 (fluid infusion followed by enalaprilat infusion, N = 5. All animals were observed for a 120 min after bacterial infusion. Mean arterial pressure, cardiac output (CO, portal vein blood flow (PVBF, systemic and regional oxygen-derived variables, and lactate levels were measured. Rapid and progressive reductions in CO and PVBF were induced by the infusion of live bacteria, while minor changes were observed in mean arterial pressure. Systemic and regional territories showed a significant increase in oxygen extraction and lactate levels. Widening venous-arterial and portal-arterial pCO2 gradients were also detected. Fluid replacement promoted transient benefits in CO and PVBF. Enalaprilat after fluid resuscitation did not affect systemic or regional hemodynamic variables. We conclude that in this model of normotensive sepsis inhibition of angiotensin-converting enzyme did not interfere with the course of systemic or regional hemodynamic and oxygen-derived variables.

Theories of cause (consideration of contract in the Serbian doctrine of civil law after the adoption of the Law on Obligations

Directory of Open Access Journals (Sweden)

Dudaš Atila

2012-01-01

Full Text Available The adoption of the Law on Obligations in 1978 can certainly be considered as an event of watershed importance in respect to the analysis of various theoretical points of view on the notion of cause (consideration of contract in the Serbian literature. The fact that it had not been explicitly regulated in Serbian positive law until the adoption of Law had a profound impact on the evolution of doctrine in this period. The range of differing theoretical points of view was very wide, covering essentially all the relevant streams in the doctrine of cause, from the ones accepting it (so-called causalistic theories, through the ones explaining it solely by the notion of exchange of assets (so-called economic theories, to the ones denying its legal significance in any sense (so called anticausalistic theories. The most distinguished authorities in Serbian literature of contract law, who studied the notion of cause of contract in the period until the promulgation of the Law, were Dragoljub Aranđelović, Živojin Perić, Lazar Marković, Andrija Gams, Stevan Jakšić, Vladimir Kapor and Mihailo Konstantinović. The Law on Obligations explicitly regulates the notion of cause of contract as one of the preconditions of validity and effect of a contract, which had a substantial impact on the evolution of doctrine. On the one hand, being an institution of positive law, there is hardly an author who had not devoted some attention to the notion of cause of contract. In this paper the author analyzes the points of view of Stojan Cigoj, Ljubiša Milošević, Živomir Đorđević, Boris Vizner, Martin Vedriš, Želimir Šmalcelj, Jakov Radišić, Slobodan Perović, Jožef Salma and Oliver Antić. On the other hand, the scope of various, often conflicting, theories on cause of contract in Serbian literature shrank. One can recognize a tendency of abandonment of points of view disavowing any legal relevance of cause of contract and the majority of contemporary

Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury

Directory of Open Access Journals (Sweden)

Honglei Guo

2016-01-01

Full Text Available Aldosterone (Aldo is critically involved in the development of renal injury via the production of reactive oxygen species and inflammation. Endoplasmic reticulum (ER stress is also evoked in Aldo-induced renal injury. In the present study, we investigated the role of ER stress in inflammation-mediated renal injury in Aldo-infused mice. C57BL/6J mice were randomized to receive treatment for 4 weeks as follows: vehicle infusion, Aldo infusion, vehicle infusion plus tauroursodeoxycholic acid (TUDCA, and Aldo infusion plus TUDCA. The effect of TUDCA on the Aldo-infused inflammatory response and renal injury was investigated using periodic acid-Schiff staining, real-time PCR, Western blot, and ELISA. We demonstrate that Aldo leads to impaired renal function and inhibition of ER stress via TUDCA attenuates renal fibrosis. This was indicated by decreased collagen I, collagen IV, fibronectin, and TGF-β expression, as well as the downregulation of the expression of Nlrp3 inflammasome markers, Nlrp3, ASC, IL-1β, and IL-18. This paper presents an important role for ER stress on the renal inflammatory response to Aldo. Additionally, the inhibition of ER stress by TUDCA negatively regulates the levels of these inflammatory molecules in the context of Aldo.

Ubiquitous Sensor Networks: Efisiensi Sistem Kontrol Cairan Infus Pasien Rawat Inap

Directory of Open Access Journals (Sweden)

BUDI RAHMADYA

2017-07-01

Full Text Available ABSTRAKPenelitian ini membahas tentang sistem kontrol cairan infus pada pasien dengan memanfaatkan teknologi sensor networks dan mikrokontroler arduino uno.  Sensor yang digunakan adalah sensor Ultrasonik HC-SR04 yang difungsikan untuk mendeteksi sisa cairan infus. Data yang terbaca oleh sensor dikirimkan menggunakan jaringan nirkabel/wireless dari Transmitter (Tx di ruang pasien ke Receiver (Rx di ruang perawat dengan menggunakan modul wireless Xbee S2. Efisiensi dari sistem kontrol yang dibuat yaitu ketika sensor mendeteksi cairan infus mendekati batas habis cairan yang telah ditentukan maka motor yang berada pada selang infus akan berfungsi untuk menutup aliran cairan infus pada selang. Dari simulasi yang dilakukan, didapatkan hasil presentasi error ketinggian cairan infus sebesar 1.96% dan presentasi error volume cairan sebesar 2.16%. Performa dari modul wireless Xbee S2 juga di ujicoba dengan mengirimkan data dari Xbee end device ke Xbee coordinator dalam penelitian ini. Kata kunci: Infus, Sensor Networks, Sensor Ultrasonik HC-SR04, Xbee S2 dan Mikrokontroler Arduino Uno.ABSTRACTThis research discusses about intravenous fluids Control System on Patients, utilizing sensor network technology and Arduino Uno microcontroller. We used  HC-SR04 Ultrasonic sensors to detect the review time intravenous fluids. The sensors data is readable by transmitted using wireless network/wireless from Transmitter (Tx in Patients Into Space Receiver (Rx at nurse room with using XBee wireless device S2. The efficiency of the control system were made, namely when the sensor detects the approaching limits of intravenous fluids discharged liquid that has been determined then the motor that was on the infus line will serve to close the infusion fluid flow in the line. In our simulations we found, the findings obtained Presentation intravenous fluids altitude error is 1.96% and presentations volume Liquid error is 2.16%. The performance of network devices XBee S2

The satiety effects of intragastric macronutrient infusions in fatty and lean Zucker rats.

Science.gov (United States)

Maggio, C A; Greenwood, M R; Vasselli, J R

1983-09-01

To evaluate satiety in the hyperphagic, genetically obese Zucker "fatty" (fafa) rat, food-deprived fatty and lean (FaFa) control rats were given equicaloric intragastric infusions consisting largely of fat, carbohydrate, or protein. Relative to distilled water infusion, these infusions resulted in immediate reductions of food intake in both fatty and lean rats allowed to feed 20 min post-infusion. Cumulative food intakes remained reduced throughout the 2 hr period of observation. Thus, despite its hyperphagia, the fatty rat is responsive to the satiating effect of infused nutrients. However, the relative satiating effectiveness of the macronutrient infusions differed for the two genotypes. In lean rats, the different macronutrient infusions resulted in equivalent reductions of feeding. In contrast, in fatty rats, fat was the least satiating and protein was the most satiating macronutrient. Moreover, compared to lean rats, fatty rats displayed less initial suppression of feeding after fat infusion and greater overall suppression after protein infusion. These effects are consistent with the long-term feeding behavior of the fatty rat for the different macronutrients and may be related to pre- and postabsorptive metabolic alterations that have been documented in this animal.

About the composition and processing of precious metals from the Serbian medieval mines

Directory of Open Access Journals (Sweden)

Kovačević-Kojić Desanka

2013-01-01

Full Text Available Account Books of the Caboga (Kabužić Brothers 1426-1433 (Squarço - Reminder, Diary and Ledger from the Historical Archive of Dubrovnik provide new evidence about the high degree of treatment and composition of precious metals from the Serbian medieval mines. First of all, that the residue, after the purification of unprocessed into fine silver, was copper. Even the price of this process is listed. In the Squarço, in two items in a receipt from 1430, there is previously unknown data about auriferous silver (argento di glama, the composition of which, besides gold, also included copper, and the precisely determined shares of these metals per litre. Apart from the Account Books of the Caboga (Kabužić Brothers, other written sources and hitherto geological explorations have provided no clues regarding the presence of copper in the auriferous silver mines.

A case for the introduction of numerical fiscal rules in the Serbian Constitution

Directory of Open Access Journals (Sweden)

Begović Boris

2017-01-01

Full Text Available The recommendation of numerical fiscal rules in Serbia, presented in this paper, is based on the inherent bias of fiscal policy towards expenditure, and consequently continuous fiscal deficit and excessive sovereign debt. It is recommended that simple and straightforward numeric fiscal rules should be introduced into the Serbian Constitution. There should be two cumulative numerical fiscal rules, the first regarding the ceiling on sovereign debt and the second regarding the ceiling on net new borrowing. Neither of the rules may be violated. The ceiling on the debt level should be prescribed by the Constitution. The ceiling on new net borrowing should depend on the distance of the sovereign debt from the debt ceiling. An illustrative example is provided, with a debt ceiling of 60%. However, the Fiscal Council should specify a specific sovereign debt ceiling as part of the proposed constitutional amendment.

Clinical experience with contrast infusion sonography as an Essure confirmation test.

Science.gov (United States)

Connor, Viviane F

2011-06-01

The purpose of this study was to assess the clinical experience, including the feasibility, safety, compliance, and efficacy, of contrast infusion sonography as an Essure (Conceptus Inc, Mountain View, CA) confirmation test. A retrospective chart review and telephone survey were conducted at an academic multispecialty group. The study participants were women with Essure intervention who underwent contrast infusion sonography, transvaginal sonography, and hysterosalpingography as Essure confirmation tests. The main outcome measures included the feasibility, safety, compliance, and efficacy of contrast infusion sonography as a first-line Essure confirmation test. A total of 118 women had successful bilateral Essure placement. Of the 63 who consented to contrast infusion sonography, 53 (84.1%) had proper bilateral placement and tubal occlusion and were encouraged to rely on Essure. Four were suspected of having unilateral tubal patency; hysterosalpingography in 2 confirmed bilateral tubal occlusion, and 2 were noncompliant with second-line hysterosalpingography. Three patients suspected of having unsatisfactory or uncertain placement on initial transvaginal sonography were encouraged to undergo hysterosalpingography in lieu of contrast infusion sonography, which confirmed unsatisfactory placement in 2 and proper placement and occlusion in 1. Three contrast infusion sonographic procedures could not be completed because of technical issues; therefore, contrast infusion sonography was feasible in 95.2% of the patients (60 of 63). No notable adverse events occurred. Only 17 patients were noncompliant with any confirmation test, yielding an overall compliance rate of 86% (101 of 118). No pregnancies occurred during 669 woman-months of follow-up. The average reimbursement for contrast infusion sonography was US$251.78. Preliminary clinical data suggest that contrast infusion sonography is a feasible, safe, and accurate Essure confirmation test, which is well accepted by

Thallium-201 infusion imaging

International Nuclear Information System (INIS)

Alazraki, N.; Kralios, A.; Wooten, W.W.

1988-01-01

To test the accuracy of Thallium-201 coronary artery infusion imaging of the earth during rapid changes in blood flow through a major coronary artery, the author performed a study in dogs correlating electromagnetic flow probe recordings with 201 Tl scintillation camera acquisitions. Hyperemic vascular response was produced experimentally in a major coronary artery by occlusion and release interventions which altered flow from baseline to zero during occlusion (20 seconds), followed by rapid flow increases approaching three times baseline immediately upon release of the occlusion. Flow returned to the baseline level within 60 seconds following release. Flow was also altered in a controlled fashion by other interventions. Recordings of Thallium uptake in the myocardium were displayed as a time histogram (counts per second squared vs time) which correlated very closely with electromagnetic flow probe recordings of flow (R=o.82-0.97). These experiments demonstrate a high degree of accuracy in Thallium infusion imaging to detect rapid changes in flow through a major coronary artery

Incidence and severity of phlebitis in patients receiving peripherally infused amiodarone.

Science.gov (United States)

Boyce, Brenda A Brady; Yee, Barbara Homer

2012-08-01

Nurses noted that the rate of phlebitis was high when intravenous amiodarone was infused via a peripheral site. Hospital policy recommends a central vascular catheter, but this method is often not feasible because the drug is administered in emergent situations for short periods. To determine the rate and severity of phlebitis in patients given peripherally infused amiodarone. The literature, policy, and procedures for administration of amiodarone were reviewed; the pharmacy was consulted; and a data collection tool was developed. The tool was pilot tested and revised, and face validation was established. Data were collected during a 6-month period. A convenience sample was used. The study included a total of 12 patients. Each new infusion of intravenous amiodarone was considered a separate occurrence, for a total of 24 infusions. Various grades of phlebitis developed in 8 patients (67%). Phlebitis developed at 12 of the 24 infusion sites (50%). Patients receiving peripherally infused amiodarone are at high risk for phlebitis. This complication may lead to infection, additional medical intervention, delay in treatment, and prolonged hospitalization.

Effects of radiolabelled monoclonal antibody infusion on blood leukocytes in cancer patients

International Nuclear Information System (INIS)

Gridley, D.S.; Slater, J.M.; Stickney, D.R.

1990-01-01

This study was undertaken to investigate the effects of a single infusion of radiolabelled murine monoclonal antibody (MAb) on peripheral blood leukocytes in cancer patients. Eleven patients with disseminated colon cancer, malignant melanoma, or lung adenocarcinoma were infused with 111In-labelled anti-ZCE 025, anti-p97 type 96.5c, or LA 20207 MAb, respectively. Blood samples were obtained before infusion, immediately after infusion (1 hr), and at 4 and 7 days postinfusion. Flow cytometry analysis of CD3+, CD4+, CD8+, CD16+, and CD19+ lymphocytes showed increasing CD4:CD8 ratios in seven patients after infusion. This phenomenon was not restricted to antibody subclass or to type of cancer. Two of the remaining patients exhibited a marked post-infusion increase in CD8+ cells. In all three patients with malignant melanoma, decreasing levels of CD16+ lymphocytes were noted after infusion and natural killer cell cytotoxicity showed fluctuations which paralleled the changes in the CD16+ subpopulation. Oxygen radical production by phagocytic cells was markedly affected in three subjects. These results suggest that a single infusion of radiolabelled murine MAb may alter the balance of critical lymphocyte subpopulations and modulate other leukocyte responses in cancer patients

Absorption of subcutaneously infused insulin: influence of the basal rate pulse interval.

Science.gov (United States)

Hildebrandt, P; Birch, K; Jensen, B M; Kühl, C; Brange, J

1985-01-01

Eight insulin-dependent diabetic patients were given two constant infusions (each 1 IU/h) of 125I-labeled insulin into the abdominal subcutaneous tissue for about 12 h. Insulin was infused in pulses into one side of the abdomen in 6-min intervals (by means of an Auto-Syringe pump) and in the other side of the abdomen, insulin was infused in 1-h intervals (by means of a Medix pump). The size of the subcutaneous depots was continuously measured by counting the radioactivity at the infusion sites. After starting the infusions, the two depots were built up to steady-state levels at the same time and of the same size (approximately 3 IU) and with similar absorption rates. Thus, during basal rate insulin infusion, identical insulin absorption kinetics was achieved, irrespective of a 10-fold difference in the pulse rate.

A new infusion pathway monitoring system utilizing electrostatic induced potential.

Science.gov (United States)

Maki, Hiromichi; Yonezawa, Yoshiharu; Ogawa, Hidekuni; Ninomiya, Ishio; Sada, Kouji; Hamada, Shingo; Hahn, Alien W; Caldwell, W Morton

2006-01-01

We have developed a new infusion pathway monitoring system employing linear integrated circuits and a low-power 8-bit single chip microcomputer. The system is available for hospital and home use and it constantly monitors the intactness of the pathway. The sensor is an electro-conductive polymer electrode wrapped around the infusion polyvinyl chloride infusion tube. This records an AC (alternating current) voltage induced on the patient's body by electrostatic coupling from the normal 100 volt, 60 Hz AC power line wiring field in the patient's room. If the injection needle or infusion tube becomes detached, then the system detects changes in the induced AC voltage and alerts the nursing station, via the nurse call system or PHS (personal handy phone System).

Analog experiment of transarterial catheter hyperthermic infusion in vitro

International Nuclear Information System (INIS)

Fan Shufeng Li Zheng; Gu Weizhong; Ru Fuming

2006-01-01

Objective: To investigate the factors related to the heating effect by transarterial catheter hyperthermic infusion with the evaluation of the feasibility in controlling the tumor temperature. Methods: Infusing 55-68 degree C liquid at the speed of 10-40 ml/min through 6F, 5F or 3F catheter with different length respectively under the similar clinical condition. The liquid temperature at the terminal exit of the catheter was measured with a digital thermometer. The factors related to the liquid temperature at the exit of the catheter were analyzed by multiple regression analysis. Results: The infusion temperature , rate and the catheter length were the main related factors to the liquid temperature at the exit of the catheter as the condition similar in clinical use. When 60-65 degree C liquid was infused at the rate of 20-40 ml/min through 5F catheter with length of 80 cm, the mean and 95% confident interval of the liquid temperature at the catheter exit were (47.55±0.44) degree C and 44.61-48.49 degree C respectively. Conclusions: The liquid temperature at the exit of infusion catheter can be regulated and controlled through adjusting the liquid perfusion temperature and speed. (authors)

Effect of Intravenous Infusion Solutions on Bioelectrical Impedance Spectroscopy.

Science.gov (United States)

Yap, Jason; Rafii, Mahroukh; Azcue, Maria; Pencharz, Paul

2017-05-01

Bioelectrical impedance (BIA) is often used to measure body fluid spaces and thereby body composition. However, in acute animal studies, we found that impedance was driven by the saline content of intravenous (IV) fluids and not by the volume. The aim of the study was to investigate the effect of 3 different fluids acutely administered on the change in impedance, specifically resistance (R). Nine healthy adults participated in 3 treatment (0.9% saline, 5% dextrose, and a mixture of 0.3% saline + 3.3% dextrose) experiments on nonconsecutive days. They all received 1 L of one of the treatments intravenously over a 1-hour period. Repeated BIA measurements were performed prior to IV infusion and then every 5 minutes for the 1-hour infusion period, plus 3 more measurements up to 15 minutes after the completion of the infusion. The change in R in the 0.9% saline infusion experiment was significantly lower than that of the glucose and mixture treatment ( P < .001). Bioelectrical impedance spectroscopy and BIA measure salt rather than the volume changes over the infusion period. Hence, in patients receiving IV fluids, BIA of any kind (single frequency or multifrequency) cannot be used to measure body fluid spaces or body composition.

Intravenous Ketamine Infusions for Neuropathic Pain Management: A Promising Therapy in Need of Optimization.

Science.gov (United States)

Maher, Dermot P; Chen, Lucy; Mao, Jianren

2017-02-01

Intravenous ketamine infusions have been used extensively to treat often-intractable neuropathic pain conditions. Because there are many widely divergent ketamine infusion protocols described in the literature, the variation in these protocols presents a challenge for direct comparison of one protocol with another and in discerning an optimal protocol. Careful examination of the published literature suggests that ketamine infusions can be useful to treat neuropathic pain and that certain characteristics of ketamine infusions may be associated with better clinical outcomes. Increased duration of relief from neuropathic pain is associated with (1) higher total infused doses of ketamine; (2) prolonged infusion durations, although the rate of infusion does not appear to be a factor; and (3) coadministration of adjunct medications such as midazolam and/or clonidine that mitigate some of the unpleasant psychomimetic side effects. However, there are few studies designed to optimize ketamine infusion protocols by defining what an effective infusion protocol entails with regard to a respective neuropathic pain condition. Therefore, despite common clinical practice, the current state of the literature leaves the use of ketamine infusions without meaningful guidance from high-quality comparative evidence. The objectives of this topical review are to (1) analyze the available clinical evidence related to ketamine infusion protocols and (2) call for clinical studies to identify optimal ketamine infusion protocols tailored for individual neuropathic pain conditions. The Oxford Center for Evidence-Based Medicine classification for levels of evidence was used to stratify the grades of clinical recommendation for each infusion variable studied.

Vasiljević’s collections of folk melodies: A Serbian musical treasure

Directory of Open Access Journals (Sweden)

Radinović Sanja

2016-01-01

Full Text Available Miodrag A. Vasiljević (1903-1963 was given a unique opportunity to span two great developmental stages in the history of Serbian ethnomusicology, occurring in the middle of the 20th century. The first of them was between the two World Wars, the stage in which Serbian musical folklore became Vasiljević’s life passion and in which he accomplished his early professional achievements. In the next stage, which started after World War II, he reached the zenith of his creation in slightly less than twenty years, setting new standards of the discipline, and providing fundamental directions for his successors, thereby immeasurably enlarging the corpus of collected material. Due all of these revolutionary innovations from the post-war period, Vasiljević is rightly considered to be not only the founder of modern Serbian ethnomusicology, but also the first person in Serbia worthy of being called an ethnomusicologist in the full sense of the word. Of the numerous results by which Vasiljević permanently indebted his people, the most pronounced does not belong to the category of pioneering endeavours, but is manifested in his melographic opus - an achievement which even today has not been surpassed in Serbia in terms of its span, scope and value. Such great productivity in recording resulted from the fact that Vasiljević had been devoted to melography from his childhood, and most intensely from 1932 to the end of his life. The exact number of examples which Vasiljević transcribed directly in the field before 1951 and those which he recorded on a tape-recorder after that time is still unknown, since many of them are still unavailable to the public, but it can be assumed that there are several thousand melodies in total. Among them are 3,198 which have already been published. That precious corpus of Vasiljević’s available material is contained in twelve collections (the largest number ever regarding any collector in Serbia so far, issued from 1950 to

Plasma concentrations of fentanyl with subcutaneous infusion in palliative care patients.

Science.gov (United States)

Miller, R S; Peterson, G M; Abbott, F; Maddocks, I; Parker, D; McLean, S

1995-12-01

1. Plasma concentrations of fentanyl were measured by g.c. in 20 patients (median age: 75 years and range: 54-86 years; eight females) in palliative care receiving the drug by continuous s.c. infusion (median rate: 1200 micrograms day-1 and range: 100-5000 micrograms day-1). 2. The infusion rate was significantly related to the duration of therapy (Spearman rho = 0.56, P Infusion rates and both total and unbound plasma concentrations of fentanyl were correlated (Spearman rho = 0.92, P infusion in the palliative care setting, which necessitates careful titration of dosage according to individual clinical response.

LPS infusion suppresses serum FGF21 levels in healthy adult volunteers

DEFF Research Database (Denmark)

Lauritzen, Esben Stistrup; Rittig, Nikolaj; Bach, Ermina

2017-01-01

circulating levels of FGF21 after lipopolysaccharide (LPS) infusion. DESIGN: Two randomized, single blinded, placebo-controlled crossover trials were used. SETTING: The studies were performed at a university hospital clinical research center. PATIENTS AND INTERVENTIONS: Study 1 (LPS bolus): Eight young......, healthy, lean males were investigated two times: 1) after isotonic saline injection, and 2) after LPS injection (bolus of 1 ng/kg). Each study day lasted 4 hours. Study 2 (continuous LPS infusion): Eight, healthy males were investigated two times: 1) during continuously isotonic saline infusion, and 2......) during continuously LPS infusion (0.06 ng/kg/h). Each study day lasted 4 hours. Circulating FGF21 levels were quantified every second hour by an immunoassay. RESULTS: A LPS bolus resulted in a late suppression (t = 240 minutes) of serum FGF21 (P=0.035). Continuous LPS infusion revealed no significant...

Intra-arterial cis-diamminedichloroplatinum infusion treatment for widespread hepatocellular carcinoma

International Nuclear Information System (INIS)

Park, Sung Il; Yang, Hee Chul; Lee, Do Yon; Shim, Yong Woon; Kim, Sang Heum; Kim, Myeong Jin; Lee, Jong Tae; Yoo, Hyung Sik

1997-01-01

The purpose of this study is to evaluate the therapeutic efficacy of intra-arterial infusion of Cis-diamminedichloroplatinum (C-DDP) for the treatment of hepatocellular carcinomas with widespread involvement. We retrospectively analyzed 22 patients who between July 1994 and June 1996 had undergone intra-arterial c-DDP infusion therapy for the treatment of hepatocellular carcinomas with widespread involvement. The hepatomas involved both lobes in ten, portal venous obstructions in fourteen, arterio-portal shunts in nine, and arterio-venous shunts in two. Proper hepatic artery was selected for infusion of 100 mg/BSA of C-DDP. The same procedure was repeated every 3 to 4 weeks, and the total number of infusions was 65. On the basis of WHO criteria, response was classified as complete remission, partial remission, stable, or progression of the disease. Six-month and one-year survival rates were estimated, and adverse reactions were evaluated. Although the response rate is not high, intra-arterial C-DDP infusion therapy can be used as an alternative treatment for hepatocellular carcinomas with widespread involvement; adverse reactions are tolerable. (author). 16 refs., 3 figs

Vascular effects of intravenous intralipid and dextrose infusions in obese subjects.

Science.gov (United States)

Gosmanov, Aidar R; Smiley, Dawn D; Peng, Limin; Siquiera, Joselita; Robalino, Gonzalo; Newton, Christopher; Umpierrez, Guillermo E

2012-10-01

Hyperglycemia and elevated free fatty acids (FFA) are implicated in the development of endothelial dysfunction. Infusion of soy-bean oil-based lipid emulsion (Intralipid®) increases FFA levels and results in elevation of blood pressure (BP) and endothelial dysfunction in obese healthy subjects. The effects of combined hyperglycemia and high FFA on BP, endothelial function and carbohydrate metabolism are not known. Twelve obese healthy subjects received four random, 8-h IV infusions of saline, Intralipid 40 mL/h, Dextrose 10% 40 mL/h, or combined Intralipid and dextrose. Plasma levels of FFA increased by 1.03±0.34 mmol/L (p=0.009) after Intralipid, but FFAs remained unchanged during saline, dextrose, and combined Intralipid and dextrose infusion. Plasma glucose and insulin concentrations significantly increased after dextrose and combined Intralipid and dextrose (all, pdextrose infusion had neutral effects on BP and FMD. The co-administration of lipid and dextrose decreased FMD by 2.4%±2.1% (p=0.002) from baseline, but did not significantly increase systolic or diastolic BP. Short-term Intralipid infusion significantly increased FFA and BP; in contrast, FFA and BP were unchanged during combined infusion of Intralipid and dextrose. Combined Intralipid and dextrose infusion resulted in endothelial dysfunction similar to Intralipid alone. Copyright © 2012 Elsevier Inc. All rights reserved.

Technology Infusion Challenges from a Decision Support Perspective

Science.gov (United States)

Adumitroaie, V.; Weisbin, C. R.

2009-01-01

In a restricted science budget environment and increasingly numerous required technology developments, the technology investment decisions within NASA are objectively more and more difficult to make such that the end results are satisfying the technical objectives and all the organizational constraints. Under these conditions it is rationally desirable to build an investment portfolio, which has the highest possible technology infusion rate. Arguably the path to infusion is subject to many influencing factors, but here only the challenges associated with the very initial stages are addressed: defining the needs and the subsequent investment decision-support process. It is conceivable that decision consistency and possibly its quality suffer when the decision-making process has limited or no traceability. This paper presents a structured decision-support framework aiming to provide traceable, auditable, infusion- driven recommendations towards a selection process in which these recommendations are used as reference points in further discussions among stakeholders. In this framework addressing well-defined requirements, different measures of success can be defined based on traceability to specific selection criteria. As a direct result, even by using simplified decision models the likelihood of infusion can be probed and consequently improved.

Antioxidant and Astroprotective Effects of a Pulicaria incisa Infusion

Directory of Open Access Journals (Sweden)

Anat Elmann

2012-01-01

Full Text Available Oxidative stress is involved in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases. Astrocytes, the most abundant glial cells in the brain, protect neurons from reactive oxygen species (ROS and provide them with trophic support, such as glial-derived neurotrophic factor (GDNF. Thus, any damage to astrocytes will affect neuronal survival. In the present study, an infusion prepared from the desert plant Pulicaria incisa (Pi was tested for its protective and antioxidant effects on astrocytes subjected to oxidative stress. The Pi infusion attenuated the intracellular accumulation of ROS following treatment with hydrogen peroxide and zinc and prevented the H2O2-induced death of astrocytes. The Pi infusion also exhibited an antioxidant effect in vitro and induced GDNF transcription in astrocytes. It is proposed that this Pi infusion be further evaluated for use as a functional beverage for the prevention and/or treatment of brain injuries and neurodegenerative diseases in which oxidative stress plays a role.

Rapid-infusion rituximab in lymphoma treatment: 2-year experience in a single institution.

Science.gov (United States)

Atay, Sevcan; Barista, Ibrahim; Gundogdu, Fatma; Akgedik, Kiymet; Arpaci, Afey

2012-05-01

Rituximab is a chimeric anti-CD20 monoclonal antibody. We aimed to explore the safety and tolerability of rapid infusion rituximab, (over 90 minutes) in patients with non-Hodgkin's lymphoma at Hacettepe University Department of Medical Oncology. Adult patients diagnosed with non-Hodgkin's lymphoma who were to receive rituximab were included in the study. The schedule of administration for cycle 1 was unaltered and delivered according to the product monograph. All subsequent cycles were administered over a total infusion time of 90 minutes (20% of the dose in the first 30 minutes, then the remaining 80% over 60 minutes, total dose delivered in 500 mL). All patients were observed for infusion-related reactions during the rituximab infusion, and vital signs were recorded every 15 minutes. From July 2006 to December 2008, 75 patients with non-Hodgkin's lymphoma were treated with rituximab-based chemotherapy. A total of 372 infusions were administered. The majority of patients were treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone, or rituximab only. The 90-minute rituximab infusion schedule was well tolerated, with no grade 3 or 4 infusion-related adverse events observed. A rapid infusion rituximab over 90 minutes is well tolerated and safe when administered as the second and subsequent infusions in the course of therapy.

Tracer studies with aortic infusion result in improper tracer distribution

International Nuclear Information System (INIS)

Wisneski, J.A.; Brooks, G.A.; Neese, R.A.; Stanley, W.C.; Morris, D.L.; Gertz, E.W.

1986-01-01

It has been suggested that lactate turnover can be accurately assessed by infusing radioactive lactate tracer into the aorta and sampling blood in the vena cava. However, there may be streaming of newly infused tracer in the aorta, resulting in a nonuniform arterial specific activity (SA). Furthermore vena caval blood may not be representative of mixed venous blood. The authors examined this problem in 7 anesthetized dogs with sampling catheters in the pulmonary (PA), carotid (CA), and femoral (FA) arteries, and the superior (SVC) and inferior (IVC) vena cavi. [1- 14 C]lactate was continuously infused into the left ventricle through a catheter introduced through the femoral artery. The same SA (dpm/μmol) was found in the CA and FA, indicating adequate mixing of newly infused tracer with trace. Three dogs showed differences between SVC, IVC and PA, suggesting a mixed venous sample can not be obtained from the VC. When the catheter was moved into the aorta, wide differences in SA appeared between the CA and FA, clearly reflecting streaming of tracer. These differences also appeared in the SVC and IVC. In conclusion, adequate mixing does not occur between tracer and trace in arterial blood with aortic infusion. Further, VC sampling will not give a consistent mixed venous SA. Therefore, for practical reasons, aortic tracer infusion with vena caval sampling will lead to erroneous turnover values

Scavenged body heat powered infusion pump

International Nuclear Information System (INIS)

Bell, Alexander; Ehringer, William D; McNamara, Shamus

2013-01-01

An infusion pump powered by body heat is investigated in this paper, with the goal of addressing the needs of dermal wound healing. The infusion pump incorporates a Knudsen gas pump, a type of thermally driven pump, to pneumatic push the pharmaceutical agent from a reservoir. Two designs are considered: an integrated pump and reservoir, and a design with cascaded pump and reservoir. Thermal models are developed for both pumps, and the simulations agree well with the experimental results. The integrated pump and reservoir design uses hydrophobic materials to prevent a flow from occurring unless the infusion pump is placed on a human body. Flow rates in the µL min −1 range for the integrated pump and reservoir, and approximately 70 µL min −1 for the cascaded pump were obtained. The dynamic behavior of the cascaded pump is described based on the thermal models. Multiple copies of the cascaded pump are easily made in series or parallel, to increase either the pressure or the flow rate. The flow rate of multiple pumps in series does not change, and the pressure of multiple pumps in parallel does not change. (paper)

A new venous infusion pathway monitoring system.

Science.gov (United States)

Maki, Hiromichi; Yonezawa, Yoshiharu; Ogawa, Hidekuni; Ninomiya, Ishio; Sata, Koji; Hamada, Shingo; Caldwell, W Morton

2007-01-01

A new infusion catheter pathway monitoring system employing linear integrated circuits and a low-power 8-bit single chip microcomputer has been developed for hospital and home use. The sensor consists of coaxial three-layer conductive tapes wrapped around the polyvinyl chloride infusion tube. The inner tape is the main electrode, which records an AC (alternating current) voltage induced on the patient's body by electrostatic coupling from the normal 100 volt, 60 Hz AC power line wiring field in the patient's room. The outside tape layer is a reference electrode to monitor the AC voltage around the main electrode. The center tape layer is connected to system ground and functions as a shield. The microcomputer calculates the ratio of the induced AC voltages recorded by the main and reference electrodes and if the ratio indicates a detached infusion, alerts the nursing station, via the nurse call system or low transmitting power mobile phone.

From communism to capitalism via the wars: The landscape of Serbian music 1985-2005

Directory of Open Access Journals (Sweden)

Milin Melita

2008-01-01

Full Text Available Two related processes were taking place in ex-Yugoslavia during the chosen period: 1 The transition from communism to capitalism, and 2 unsuccessful dealing with the political/economical crisis that led to the wars in the 1990s, both followed by the necessity to face the outcome and establish new identities. Although those eventful and tragic two decades have deeply shaken Serbian society, the art music production has not mirrored them in ways that might have been expected. Whereas pacifistic and oppositional political ideas were openly voiced in the public life, the majority of composers wished to distance themselves from explicit engagement in their works. That was probably due to the mistrust that art music, whose influence has always been very limited in the country, could make a strong impact on the political events.

Effect of glucose-insulin-potassium infusion on thallium myocardial clearance

International Nuclear Information System (INIS)

Wilson, R.A.; Okada, R.D.; Strauss, H.W.; Pohost, G.M.

1983-01-01

Factors influencing the rate of 201 Tl clearance from the myocardium have not been clearly defined. This study determined the effect of an intravenous infusion of glucose-insulin-potassium (GIK) on the net 201 Tl clearance rates from myocardium with and without initial 201 Tl loading. Anesthetized open-chest dogs underwent 5 min of left anterior descending coronary artery occlusion and intravenous 201 Tl was injected and the occlusion released 5 min later. Thirty minutes after 201 Tl injection, 30 ml of either GIK (nine dogs) or saline (five dogs) was infused intravenously. The clearance rates of 201 Tl from the anterior wall (without initial 201 Tl loading) and from the posterior wall (with initial 201 Tl loading) were monitored with miniaturized cadmium telluride detectors placed on the myocardium. Calculation of net myocardial clearance rates was performed by linear regression analysis from serial 1 min counts. Compared with saline infusion, GIK increased the net clearance of 201 Tl from both myocardial regions with and without initial loading. The most marked change induced by GIK infusion was in the myocardial region without initial 201 Tl loading; a net increase in 201 Tl activity (72 +/- 42 cpm/30 min) was converted into a net loss (-594 +/- 228 cpm/30 min). There was no significant change in 201 Tl clearance after the saline infusion. Heart rate, aortic and left atrial pressure, sonomicrometer-measured transmural myocardial wall thickness, microsphere-determined myocardial blood flow, and blood glucose and potassium concentrations did not change significantly during GIK or saline infusions. Thus, GIK infusion appears to increase net 201 Tl clearance from myocardial zones with and without initial 201 Tl loading

Intractable Polyuria Mimicking Diabetes Insipidus-Source Traced to Vecuronium Infusion.

Science.gov (United States)

Haldar, Rudrashish; Samanta, Sukhen; Singla, Ankush

2016-01-01

Continuous infusion of vecuronium is a commonly used technique for patients requiring prolonged neuromuscular blockade for mechanical ventilation. As compared with older neuromuscular blocking agents, it confers the advantages of rapid excretion and intermediate duration of action. Prolongation of neuromuscular blockade and muscle weakness are the known complications of continuous vecuronium infusion. This report attempts to describe polyuria, as a hitherto unknown complication of vecuronium infusion, which can occur due to the mannitol present in commercially available preparation of vecuronium bromide.

Attribute based selection of thermoplastic resin for vacuum infusion process

DEFF Research Database (Denmark)

Prabhakaran, R.T. Durai; Lystrup, Aage; Løgstrup Andersen, Tom

2011-01-01

The composite industry looks toward a new material system (resins) based on thermoplastic polymers for the vacuum infusion process, similar to the infusion process using thermosetting polymers. A large number of thermoplastics are available in the market with a variety of properties suitable...... for different engineering applications, and few of those are available in a not yet polymerised form suitable for resin infusion. The proper selection of a new resin system among these thermoplastic polymers is a concern for manufactures in the current scenario and a special mathematical tool would...... be beneficial. In this paper, the authors introduce a new decision making tool for resin selection based on significant attributes. This article provides a broad overview of suitable thermoplastic material systems for vacuum infusion process available in today’s market. An illustrative example—resin selection...

Infusion of hypertonic saline before elective hysterectomy: effects on cytokines and stress hormones

DEFF Research Database (Denmark)

Kolsen-Petersen, J A; Bendtzen, K; Tonnesen, E

2008-01-01

Infusion of hypertonic saline provides early haemodynamic benefits and may affect the immune system. It is unknown if infusion of hypertonic saline affects plasma cytokines and stress hormones after surgery.......Infusion of hypertonic saline provides early haemodynamic benefits and may affect the immune system. It is unknown if infusion of hypertonic saline affects plasma cytokines and stress hormones after surgery....

The structure of the lexical personality descriptors in Serbian language

Directory of Open Access Journals (Sweden)

Smederevac Snežana

2007-01-01

Full Text Available Two studies, both originating from a larger psycholexical study in Serbian language, are presented here. Two questionnaires, Lexi and PL have been constructed in the psycholexical study. The questionnaires differ by the formulation of their respective items: while the items of the Lexi contain adjectives, the items of the PL are in the form of statements. The first study presented in this paper examines the latent structure of the Lexi questionnaire, while the second one deals with the latent structure of the PL. In both studies, principal component analysis was applied, and the number of components to be retained in the analysis was determined according to the Scree criterion. Also, Promax rotation was applied in both studies. Seven components which were extracted in the first study have been interpreted as Negative Valence, Negative Emotionality, Aggressiveness, Conscientiousness, Positive Emotionality, Positive Valence and Openness to Experience. The content of these dimensions is obviously similar to the dimensions of Tellegen and Waller’s Big Seven model. In the second study, five components were extracted, and interpreted as Sociability, Anxiety, Aggressiveness, Activity and Impulsivity. The content of the dimensions extracted in the second study corresponds with the dimensions of Marvin Zuckerman’s Alternative Five - Factor Model.

Local Intraarterial Thrombolysis: In Vitro Comparison Between Automatic and Manual Pulse-Spray Infusion

International Nuclear Information System (INIS)

Froelich, Jens J.; Freymann, Christina; Hoppe, Martin; Thiel, Thomas; Wagner, H. Joachim; Barth, Klemens H.; Klose, Klaus J.

1996-01-01

Purpose: Manual and automatic pulse-spray infusion techniques are compared in vitro to evaluate the efficacy of thrombolysis and the distribution of urokinase and saline solution within thrombus using a pulse-spray catheter. Methods: A pulse-spray catheter was introduced into a human thrombus within a stenotic flow model. Automatic and manual pulsed infusion of urokinase and automatic pulsed infusion of saline solution were compared. To quantify the efficacy of thrombolysis, pressure gradients were recorded proximal and distal to the thrombus and during the course of infusion. Distribution of infused urokinase was assessed radiographically. Results: The fastest and most homogeneous dissolution of the thrombus was achieved with automatic pulsed infusion of urokinase, shown by decreasing transthrombotic pressure gradients (p < 0.001, Wilcoxon, matched pairs). Manual pulsed infusion of urokinase or saline solution resulted in inhomogeneous thrombus dissolution and delayed thrombolysis. Conclusion: Application of automatic pulse-spray injectors seems beneficial for more effective and homogeneous intraarterial pulse-spray thrombolysis when compared with conventional manual pulsed technique

Value of infusion-DSA (Digital Subtraction Angiography) in diagnosis of primary hepatocellular carcinoma

International Nuclear Information System (INIS)

Kwon, Jeong Mi; Kim, So Sun; Huh, Jin Do; Kim, Ho Joon; Chun, Byung Hee; Joh, Young Duk

1991-01-01

In order to evaluate diagnostic effectiveness of the infusion-study, the authors prospectively evaluated hepatic digital subtraction angiography of bolus and infusion studies in 71 patients with hepatocellular carcinoma. In contrast to Bolus-DSA, which involves a 2 second injection of 10cc of contrast medium, the Infusion-DSA uses a protracted (10sec) injection, a lower injection rate, and larger total dose of contrast medium (20cc). The information yield of arterial and capillary phases of Infusion-DSA was compared with that of Bolus-DSA and graded as 'improved(+)', 'equivalent( ± )', or 'poor(-)'. Also, the contribution of Infusion-DSA to the diagnosis was classified into one of five in a graded system. In 29 hepatocellular patients, the Infusion-DSA was helpful in detecting daughter nodules, fibrous capsule and arteriovenous shunt. Infusion-DSA is a useful complementary technique in the diagnosis of hepatocellular carcinoma and was also helpful in determining the selection of the therapeutic modality of hepatocellular carcinoma

Rapid-Infusion Rituximab in Lymphoma Treatment: 2-Year Experience in a Single Institution

Science.gov (United States)

Atay, Sevcan; Barista, Ibrahim; Gundogdu, Fatma; Akgedik, Kiymet; Arpaci, Afey

2012-01-01

Purpose: Rituximab is a chimeric anti-CD20 monoclonal antibody. We aimed to explore the safety and tolerability of rapid infusion rituximab, (over 90 minutes) in patients with non-Hodgkin's lymphoma at Hacettepe University Department of Medical Oncology. Patients and Methods: Adult patients diagnosed with non-Hodgkin's lymphoma who were to receive rituximab were included in the study. The schedule of administration for cycle 1 was unaltered and delivered according to the product monograph. All subsequent cycles were administered over a total infusion time of 90 minutes (20% of the dose in the first 30 minutes, then the remaining 80% over 60 minutes, total dose delivered in 500 mL). All patients were observed for infusion-related reactions during the rituximab infusion, and vital signs were recorded every 15 minutes. Results: From July 2006 to December 2008, 75 patients with non-Hodgkin's lymphoma were treated with rituximab-based chemotherapy. A total of 372 infusions were administered. The majority of patients were treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone, or rituximab only. The 90-minute rituximab infusion schedule was well tolerated, with no grade 3 or 4 infusion-related adverse events observed. Conclusion: A rapid infusion rituximab over 90 minutes is well tolerated and safe when administered as the second and subsequent infusions in the course of therapy. PMID:22942806

On metaphorical designation of humans, animals, plants and things in Serbian and English language

Directory of Open Access Journals (Sweden)

Rakić Stanimir

2004-01-01

Full Text Available In this paper I examine compound names of plants, animals, human beings and other things in which at least one nominal component designates a part of the body or clothes, or some basic elements of houshold in Serbian and English. The object of my analysis are complex derivatives of the type (adjective noun + suffix in Serbian and componds of the type noun's + noun, noun + noun and adjective + noun in English. I try to show that there is a difference in metaphorical designation of human beings and other living creatures and things by such compound nouns. My thesis is that the metathorical designation of human beings by such compounds is based on the symbolic meaning of some words and expressions while the designation of other things and beings relies on noticed similarity. In Serbian language such designation is provided by comples derivatives praznoglavac 'empty-headed person', tupoglavac 'dullard' debolokoiac 'callos person', golobradac 'young, inexperienced person' žutokljunac 'tledling' (fig, in English chicken liver, beetle brain birdbrain, bonehead, butterfingers, bigwig, blackleg, blue blood bluestocking, eat's paw, deadhead,fat-guts,fathead, goldbrick (kol hardhat, hardhead, greenhorn, redcoat (ist, redneck (sl, thickhead, etc. Polisemous compounds like eat's paw lend support for this thesis because their designation of human beings is based on symbolic meaning of some words or expressions. I hypothesize that the direction and extend of the possible metaphorization of names may be accounted for by the following hierarchy (11 people - animals - plants - meterial things. Such hierarchy is well supported by the observations of Lakoff (1987 and Taylor (1995 about the role of human body in early experience and perception ofthe reality. Different restrictions which may be imposed in the hierarchy (11 should be the matter of further study, some of which have been noted on this paper. The compounds of this type denoting people have

Chemistry in Serbian journals in the second half of the 19th century

Directory of Open Access Journals (Sweden)

Cvjetićanin Stanko M.

2008-01-01

Full Text Available The aim of this paper is selection and analysis of articles with chemistry content in selected Serbian journals in the second half of the 19th century, which were aimed towards general public, in order to get insight into the level and quality of additional chemistry informing of readers. Two journals were selected, that contained entertaining, literature and scientific content ('Sedmica' and 'Vila', and two other, with entertainment and literature nature ('Danica' and 'Matica'. The analyzed journals primarily addressed the general public and played an important role in readers' information and education. Historical method was applied in this research. The above-mentioned journals were analyzed separately, with the short historical survey. Complete editions of these journals were analyzed, and the selection of articles was made according to the textual content or the title itself. The chemistry content presented in these journals is of the great variety. Among other things, interesting comments of the chemical schoolbooks are found, as well as lectures on science.

Hereditary motor and sensory neuropathy Lom type in a Serbian family.

Science.gov (United States)

Dacković, J; Keckarević-Marković, M; Komazec, Z; Rakocević-Stojanović, V; Lavrnić, D; Stević, Z; Ribarić, K; Romac, S; Apostolski, S

2008-10-01

Hereditary motor and sensory neuropathy Lom type (HMSNL), also called CMT 4D, a hereditary autosomal recessive neuropathy, caused by mutation in N-Myc downstream regulated gene 1 (NDRG1 gene), was first described in a Bulgarian Gypsy population near Lom and later has been found in Gypsy communities in Italy, Spain, Slovenia and Hungary. We present two siblings with HMSNL, female and male, aged 30 and 26, respectively in a Serbian non-consanguineous family of Gypsy ethnic origin. They had normal developmental milestones. Both had symptoms of lower limb muscle weakness and walking difficulties with frequent falls, which began at the age of seven. At the age of 12, they developed hearing problems and at the age of 15 hand muscle weakness. Neurological examination revealed sensorineural hearing loss, dysarthria, severe distal and mild proximal muscle wasting and weakness, areflexia and impairment of all sensory modalities of distal distribution. Electrophysiological study revealed denervation with severe and early axonal loss. Sensorineural hearing loss was confirmed on electrocochleography and brainstem evoked potentials. Molecular genetic testing confirmed homozygote C564t (R148X) mutation in NDRG1 gene.

CLIMATE CHANGE AND THE RISK MANAGEMENT IN SERBIAN INLAND WATERWAY TRANSPORT

Directory of Open Access Journals (Sweden)

Todor Backalic

2012-12-01

Full Text Available Climate changes require special attention and global monitoring. Impacts on nature and industry are increasingly evident. Water transport could be the backbone of the future European combined transport system. Unfortunately, risks in water transport are perhaps an under researched area and consequently, this article outlines a rationale, why it is necessary to develop competence about risk in water transport. The development of the cargo transport in river traffic depends directly on technical-exploitative characteristics of the network of inland waterways. Research of navigational abilities of inland waterways always comes before building ships or making a transport schedule. Navigation characteristics of rivers have to be determined as precise as possible, especially from the aspect of determination the possible draught of vessels. River transport due to their operational business and environmental conditions faced with several risks having different degrees of consequences. Current risk assessment methods for water transport just consider some dramatic events. We present a new method for the assessment of risk and vulnerability of water transport where river depth represents a crucial part. The analysis of water level changes on Serbian rivers during the last sixty years was done.

Econometric modelling of Serbian current account determinants: Jackknife Model Averaging approach

Directory of Open Access Journals (Sweden)

Petrović Predrag

2014-01-01

Full Text Available This research aims to model Serbian current account determinants for the period Q1 2002 - Q4 2012. Taking into account the majority of relevant determinants, using the Jackknife Model Averaging approach, 48 different models have been estimated, where 1254 equations needed to be estimated and averaged for each of the models. The results of selected representative models indicate moderate persistence of the CA and positive influence of: fiscal balance, oil trade balance, terms of trade, relative income and real effective exchange rates, where we should emphasise: (i a rather strong influence of relative income, (ii the fact that the worsening of oil trade balance results in worsening of other components (probably non-oil trade balance of CA and (iii that the positive influence of terms of trade reveals functionality of the Harberger-Laursen-Metzler effect in Serbia. On the other hand, negative influence is evident in case of: relative economic growth, gross fixed capital formation, net foreign assets and trade openness. What particularly stands out is the strong effect of relative economic growth that, most likely, reveals high citizens' future income growth expectations, which has negative impact on the CA.

Dextrose boluses versus burette dextrose infusions in prevention of ...

African Journals Online (AJOL)

Background: Hypoglycemia is a major cause of morbidity and mortality among preterm infants and its management remains a challenge in resource limited settings. Use of dextrose infusion by the recommended infusion pumps is not feasible in our environment due to their high costs and yet the current use of mini dextrose ...

Nuclear renaissance or premature try

International Nuclear Information System (INIS)

Coderch, M.

2008-01-01

After the economic failure of the 70's and not having been able to solve for decades its multiple problems, the nuclear industry was suffering a slow but inescapable agony. However, the need to reduce CO 2 emissions and the likely arrival of the worldwide peak of oil production have infused new life to the nuclear option, and it has again become one of the main topics of discussion in the worldwide energy debate. But in this debate we tend to forget that the causes of the abrupt end of the first nuclear era have not disappeared, and that for this reason it may well be that we are lead to a repetition of the events that induced its first demise. The much talked nuclear renaissance is thus likely to end up as a premature miscarriage. (Author)

Measuring the influence of blood component infusion rate on recipient vital signs.

Science.gov (United States)

Gehrie, E A; Hendrickson, J E; Tormey, C A

2015-11-01

One of the challenges surrounding blood component administration is the determination of an appropriate rate of infusion. There are very few evidence-based guidelines available to guide healthcare providers looking for a 'standard' infusion rate for red blood cells (RBCs), plasma or platelets (PLTs). Our objective was to determine the extent to which blood component infusion rates were associated with changes in transfusion recipient vital signs. We retrospectively examined records of 3496 component infusions (RBCs, n = 2359; PLTs, n = 478; plasma, n = 659) over a 1-year period at a 362-bed multispecialty hospital. The following data were collected for each transfusion: blood product volume and infusion time, recipient pre- and post-transfusion temperature, blood pressure and pulse rate, and hospital ward where transfusion occurred. Plasma (median 10.4 ml/min) was infused faster than PLTs (median 7.2 ml/min, P 20 ml/min) and clinically significant reported changes in vital signs. There does not appear to be a strong correlation between infusion rate and significant changes in recipient temperature, blood pressure or pulse rate. Based on these data, a reasonable rate for routine transfusion is 2-3 ml/min for RBCs and 7-10 ml/min for plasma and PLTs. Faster infusion rates (>20 ml/min) likely can be applied with close patient monitoring if there is a more urgent need for transfusion. © 2015 International Society of Blood Transfusion.

Romanian-Serbian relations and the Banat question during the First World War

Directory of Open Access Journals (Sweden)

Sandu Traian

2006-01-01

Full Text Available Relations between Serbia and Romania throughout the war are viewed from the standpoint of the two countries' rivaling claims on the Banat and within the framework of power balance in the Allied camp with an emphasis on the position of the Romanian government and statesmen. Obviously, Romania's position was more favourable during the first two war years as the Allies sought to win her over for the Entente. Thus the Banat was included in compensations for her entering the war on the side of the Allies. Romania's defeat, however, produced a complete shift in the balance of power, with Romania now in an unenviable position, especially following the breach of the Salonica Front in September 1918. From the Romanian perspective, the Banat's destiny also depended on divergent political positions on the domestic scene. The fate of the Banat was eventually decided by the advancing Serbian army which took the whole territory, though under French command. The final decision became a responsibility of the Paris Peace Conference.

Subanesthetic, Subcutaneous Ketamine Infusion Therapy in the Treatment of Chronic Nonmalignant Pain.

Science.gov (United States)

Zekry, Olfat; Gibson, Stephen B; Aggarwal, Arun

2016-06-01

This study was designed to describe the efficacy and toxicity of subcutaneous ketamine infusions and sublingual ketamine lozenges for the treatment of chronic nonmalignant pain. Data were collected prospectively on 70 subjects managed in an academic, tertiary care hospital between 2007 and 2012 who received between 3 and 7 days of subanesthetic, subcutaneous ketamine infusion. Data were analyzed for efficacy, adverse effects, and reduction in use of opioid medication. We also analyzed whether subsequent treatment with sublingual ketamine lozenges resulted in longer-term efficacy of the beneficial effects of the initial ketamine infusion. There was a significant reduction in pain intensity measured by numerical rating scale (NRS) from mean of 6.38 before ketamine to 4.60 after ketamine (P ketamine infusion from a mean morphine equivalent dose (MMED) of 216 mg/day before ketamine to 89 mg/day after ketamine (P ketamine infusion was 59%. No subjects increased their use of opioids during their hospitalization for the ketamine infusion. A small proportion of subjects who responded to the infusion were continued on ketamine lozenges. This group was followed for between 3 months and 2 years. The use of ketamine lozenges after the infusion resulted in 31% of these subjects being able to cease their use of opioids compared with only 6% who did not receive ketamine lozenges. Eleven percent of subjects who received lozenges subsequently increased their opioid usage. Adverse effects were fairly common, but only mild, with 46% of patients experiencing light-headedness and dizziness, 25% tiredness and sedation, 12% headaches, 12% hallucinations, and 8% vivid dreams. Adverse effects were easily managed by reducing the rate of the ketamine infusion. The administration of subanesthetic, subcutaneous ketamine infusion was well tolerated, with mostly mild adverse effects and no serious adverse effects. The infusion provided significant pain relief in subjects who had failed a wide

[How to promote the respect of good infusion practices by meeting health care professionals?].

Science.gov (United States)

Le Reste, C; Fiedler, A; Dubois, S; Dewailly, A; Le Du, I; Cogulet, V

2016-05-01

Health care professionals often forget that there are risks associated with infusion therapy even if it is a common care. In order to assess this practice and to draw potential improvement actions, an audit of local gravity-flow intravenous infusion practices was conducted. The audit, based on a grid including 66 items from the medical prescription to the end of the infusion therapy administration, was conducted in the 6 units which use the most gravity-flow intravenous infusion devices. A multidisciplinary working group was created to decide and organize priority corrective measures in order to improve infusion practices and quality of healthcare. The audit enabled to observe 90hours of nurse's practices (96 infusions) and highlighted heterogeneity in infusion, in some cases inappropriate infusion practices and misuse of infusion devices. We found 4 main issues: labelling infusion therapy, training of health care professionals on good practices, support the purchase of infusion pumps and standardize perfusion line. An interactive educational program for nurses (workshops) was organized to enhance the respect of good practices: infusion identification at any time, respect of hygiene rules, flow rate regulation by counting drops, appropriate use of pumps and flow rate regulators. The audit drew up work priorities. The workshops made easier exchanges between professionals and had a warm welcome that's why it is essential to carry on such training. This collaborative approach between pharmacists, nurses, hygienists and biomedical technicians contribute to drug management improvement and promote optimal patient care. Copyright © 2015 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.

Animal model of rapid crystalloid infusion in rats

Directory of Open Access Journals (Sweden)

Flavio Stillitano Orgaes

2013-04-01

Full Text Available PURPOSE: To describe an animal model of rapid intravenous infusion with different volumes of crystalloid and discuss the clinical findings. METHODS: Fifty six male Wistar rats were used, divided randomly in seven groups (n = 8. The rats of groups 1 to 6 received lactated Ringer´s solution intravenously, in the rate of 25 ml/min, with different volumes proportional to blood volume (BV. The rats of group 0 were submitted to the same procedure, but did not receive the fluid (control group. The data included respiratory rate, heart rate, saturation of peripheral oxygen (SpO2 in two times (before and after the infusion, and upshots (respiratory arrest and death. Dunnett´s test and ANOVA were used. RESULTS: The clinical signs significantly changed in the 2, 2.5 and 3 fold BV groups. The respiratory arrest was observed in the 1.5, 2, 2.5 and 3 fold BV groups, but death was present only in 2.5 and 3 fold BV groups. CONCLUSIONS: The infusion of crystalloid in the same volume of blood volume did not cause significant variation in respiratory and heart rate, saturation of peripheral oxygen and did not induce respiratory arrest. The infusion of a volume of 3 fold blood volume was lethal to all animals.

Impact of infusion speed on the safety and effectiveness of prothrombin complex concentrate

OpenAIRE

Pabinger , Ingrid; Tiede , Andreas; Kalina , Uwe; Knaub , Sigurd; Germann , Reinhard; Ostermann , Helmut

2009-01-01

Abstract Prothrombin complex concentrate (PCC) infusion is preferred for emergency reversal of coumarin therapy. Rapid infusion can potentially save crucial time; however, the possible impact of high infusion speed on PCC safety and effectiveness has not been delineated. In a prospective multinational clinical trial with 43 patients receiving PCC (Beriplex? P/N) for emergency reversal of coumarin therapy, infusion speeds were selected by the investigators. In a two-phase statistica...

Infusion Nursing: An Evidence-Based Approach - Third edition Alexander Mary Infusion Nursing: An Evidence-Based Approach - Third edition 625pp Elsevier 9781416064107 1416064109 [Formula: see text].

Science.gov (United States)

2010-11-03

This book considers all aspects of infusion therapy and provides a solid evidence base. Its 30 chapters are well organised into six sections covering physiological considerations, infusion therapies and nursing practice.

A new venous infusion path monitoring system utilizing electrostatic induced potential.

Science.gov (United States)

Ogawa, Hidekuni; Yonezawa, Yoshiharu; Maki, Hiromichi; Caldwell, W Morton

2008-01-01

A new venous infusion pathway monitoring system has been developed for hospital and home use. The system consists of linear and digital integrated circuits and a low-power 8-bit single chip microcomputer which constantly monitors the infusion pathway intactness. A 330 kHz AC voltage, which is induced on the patient's body by electrostatic coupling from a 330 kHz pulse oscillator, can be recorded by main and reference electrodes wrapped around the infusion polyvinyl chloride tube. If the injection needle or infusion tube becomes detached, then the system detects changes in the induced AC voltages and alerts the nursing station, via the nurse call system or PHS (personal handy phone system).

Haemolytic anaemia as a complication to intravenous immunoglobulin infusion

DEFF Research Database (Denmark)

Markvardsen, Lars Høj; Harbo, Thomas; Christiansen, Ingelise

performed before and two weeks after infusion of IVIg. Following treatment blood haemoglobin declined from 8.6±0.8 to 8.1±1.3mmol/l, p... naive patients are susceptible to develop haemolysis. Haemolytic anaemia is a severe side effect that seems to be more frequent after immunoglobulin infusions than previously recognized....

Gaia science alerts and the observing facilities of the Serbian-Bulgarian mini-network telescopes

Directory of Open Access Journals (Sweden)

Damljanović G.

2014-01-01

Full Text Available The astrometric European Space Agency (ESA Gaia mission was launched in December 19, 2013. One of the tasks of the Gaia mission is production of an astrometric catalog of over one billion stars and more than 500000 extragalactic sources. The quasars (QSOs, as extragalactic sources and radio emitters, are active galactic nuclei objects (AGNs whose coordinates are well determined via Very Long Baseline Interferometry (VLBI technique and may reach sub-milliarcsecond accuracy. The QSOs are the defining sources of the quasi-inertial International Celestial Reference Frame (ICRF because of their core radio morphology, negligible proper motions (until sub-milliarcsecond per year, and apparent point-like nature. Compact AGNs, visible in optical domain, are useful for a direct link of the future Gaia optical reference frame with the most accurate radio one. Apart from the above mentioned activities, Gaia has other goals such as follow-up of transient objects. One of the most important Gaia's requirements for photometric alerts is a fast observation and reduction response, that is, submition of observations within 24 hours. For this reason we have developed a pipeline. In line with possibilities of our new telescope (D(cm/F(cm=60/600 at the Astronomical Station Vidojevica (ASV, of the Astronomical Observatory in Belgrade, we joined the Gaia-Follow-Up Network for Transients Objects (Gaia-FUN-TO for the photometric alerts. Moreover, in view of the cooperation with Bulgarian colleagues (in the frst place, SV, one of us (GD initiated a local mini-network of Serbian { Bulgarian telescopes useful for the Gaia-FUN-TO and other astronomical purposes. During the next year we expect a new 1.4 m telescope at ASV site. The speed of data processing (from observation to calibration server could be one day. Here, we present an overview of our activities in the Gaia-FUN-TO which includes establishing Serbian { Bulgarian mini-network (of five telescopes at three sites

Radiographic and Histologic Study After Infusion of Contrast Media into Rabbit Submandibular Gland

International Nuclear Information System (INIS)

Nah, Kyung Soo; Park, Tae Won

1990-01-01

50 submandibular glands of rabbits were examined historadiologically after infusion with normal and over volumes of physiologic saline and 5 radiographic contrast media. The results were as follows: 1. All water soluble contrast media showed similar radiographic contrasts and absorbed about 5 minutes after infusion except Telebrix 30 which took 30 minutes in both normal and overfilled glands. 2. Lipid soluble medium, Lipiodol UF had excellent radiographic contrast and could be seen on the radiograms even after 24 hours after infusion. 3. Salivary glands infused with physiologic saline didn't show any histologic changes except slight duct dilation right after infusion. 4. Telebrix 30 caused mild to moderate duct dilation and inflammation at immediate and 24 hours after infusion which was more severe in overfilled glands. At 7 days after infusion, there were mild to moderate fibrosis of the gland and areas of necrosis was seen in overfilled glands. 5. Hypaque 60% showed similar histologic reactions to Telebrix 30 except more severe tissue destruction at 7 days after infusion. 6. Urografin 60% showed mildest histologic changes among the media used in the study. 7. Biliscopin had mild duct dilation which returned to normal after 7 days but there were moderate inflammation and tissue necrosis at that time. 8. Lipiodol UF showed severe duct dilation with numerous vacuoles and there were tissue fibrosis at 7 days after infusion but no tissue necrosis was seen.

Clinical evaluation of preoperative arterial infusion chemotherapy and surgical operation for colorectal carcinoma

International Nuclear Information System (INIS)

Yuan Jianhua; Zhao Zhongsheng; Deng Gaoli; Hu Tingyang; Yu Wenqiang; Chen Fanghong; Luo Zuyan; Ru Guoqing; Dong Quanjin; Tu Shiliang

2003-01-01

Objective: To investigate the clinical values of preoperative arterial infusion chemotherapy and surgical operation for colorectal carcinoma. Methods: 66 patients with colorectal carcinoma were subjected to percutaneous femoral artery catheterization by Seldinger's technique with infusion of anti-cancer drugs. The resection was performed 5-30 days after the arterial infusion (mean 12 days). In 50 surgical specimens of the 66 cases, histological findings were evaluated including the density and distribution of the apoptosis cells under the observation by DNA nick end labelling technique. Of which 22 specimens before arterial infusion chemotherapy (got from biopsy of preoperation) and 25 normal mucosa (got from normal surgical specimens) were used as controls. Results: The total histological response rate was 100% with grade I in 20 cases, grade II in 21 cases, grade III in 9 cases. The densities of the apoptosis cells were 31.47 ± 5.58 before arterial infusion chemotherapy, 76.69 ± 17.12 after arterial infusion chemotherapy and 8.01 ± 3.39 in normal mucosa. The density of the apoptosis cells after arterial infusion chemotherapy was significantly higher than that before arterial infusion chemotherapy (P 2 =4.696, P>0.30). There were no significant differences in the apoptosis of adenocarcinoma during different pathological stages (F=0.001376, P>0.05). Conclusions: Peroperative transcatheter arterial infusion chemotherapy resulting in apoptosis of adenocarcinoma, can raise the radical operation rate, and prolong survival rate for colorectal carcinoma patients

The effect of tubing dwell time on insulin adsorption during intravenous insulin infusions.

Science.gov (United States)

Thompson, Cecilia D; Vital-Carona, Jessica; Faustino, E Vincent S

2012-10-01

Insulin adsorbs to plastic tubing, which decreases the concentration of an insulin solution delivered from an intravenous infusion set. Dwelling insulin within tubing before starting the infusion decreases adsorption but delays treatment initiation and wastes time in infusion preparation. The lack of data on dwell time effects results in wide variability in practice. We aim to determine the effect of dwell time on insulin concentration from intravenous infusion tubing. In this in vitro study, we used insulin solutions with concentrations of 0.1 unit/mL, 1 unit/mL, and 10 units/mL. Each solution dwelled in intravenous infusion sets for 0, 15, 30, or 60 min. After the dwell, we measured insulin concentrations from the solution bags and tubing. We repeated each insulin concentration-dwell time combination five times. Comparisons were performed using analyses of variance. For each of the three insulin concentrations, the mean insulin concentrations from the tubing were not significantly different between dwell times. Duration of dwell time did not affect insulin adsorption in polypropylene intravenous infusion sets. We recommend that following a 20-mL flush, insulin infusions can be started without any dwell time. Removal of dwell times may improve clinical practice by minimizing preparation time and will allow faster initiation of insulin infusion therapy.

Choice of infusion-sampling mode for tracer studies of free fatty acid metabolism

International Nuclear Information System (INIS)

Jensen, M.D.; Rogers, P.J.; Ellman, M.G.; Miles, J.M.

1988-01-01

To determine the preferred infusion-sampling mode for isotopic studies of free fatty acid (FFA) metabolism, tracer [( 14 C]palmitate) was infused into the left ventricle of five anesthetized dogs, and tracee ([ 3 H]palmitate) was infused into three separate peripheral veins of each dog. The [ 14 C]palmitate specific activity (SA) was lower in mixed venous than arterial blood, and [ 3 H]palmitate SA was equal in both sites. The actual infusion rate of [ 3 H]palmitate [2.15 +/- 0.31 X 10(5) disintegrations/min (dpm).kg-1.min-1] could be accurately predicted (2.14 +/- 0.32 X 10(5) dpm.kg-1.min-1) using the known [ 14 C]palmitate infusion rate and the arterial plasma [ 14 C]-to-[ 3 H]palmitate ratio. In contrast, the mixed venous [ 14 C]-to-[ 3 H]palmitate ratio resulted in overestimates (P less than 0.05) of the actual [ 3 H]palmitate infusion rate. In summary, venous tracer infusion with arterial blood sampling for FFA tracer studies provides the most accurate estimates of tracee rate of appearance

Infusion and sampling site effects on two-pool model estimates of leucine metabolism

International Nuclear Information System (INIS)

Helland, S.J.; Grisdale-Helland, B.; Nissen, S.

1988-01-01

To assess the effect of site of isotope infusion on estimates of leucine metabolism infusions of alpha-[4,5-3H]ketoisocaproate (KIC) and [U- 14 C]leucine were made into the left or right ventricles of sheep and pigs. Blood was sampled from the opposite ventricle. In both species, left ventricular infusions resulted in significantly lower specific radioactivities (SA) of [ 14 C]leucine and [ 3 H]KIC. [ 14 C]KIC SA was found to be insensitive to infusion and sampling sites. [ 14 C]KIC was in addition found to be equal to the SA of [ 14 C]leucine only during the left heart infusions. Therefore, [ 14 C]KIC SA was used as the only estimate for [ 14 C]SA in the equations for the two-pool model. This model eliminated the influence of site of infusion and blood sampling on the estimates for leucine entry and reduced the impact on the estimates for proteolysis and oxidation. This two-pool model could not compensate for the underestimation of transamination reactions occurring during the traditional venous isotope infusion and arterial blood sampling

Behaviour of homologous 125I fibrinogen after thrombin and ancrod infusion in rabbits

International Nuclear Information System (INIS)

Setter, R.

1977-01-01

The behaviour of radioactively labelled fibrinogen after infusion of thrombin or ancrod is investigated. Common factors and differences in the behaviour of fibrinogen after infusion of these two enzymes, which act proteolytically on the fibrinogen, are dealt with. Rabbits received an i.v. injection of homologous 125 I-fibrinogen 3 days before ancrod or thrombin infusion. On the day of the experiments, one group of animals received an ancrod infusion (1.5 U/kg body weight for 30 minutes), the other a thrombin infusion (600 U/kg body weight for 60 minutes). Intravenous ancrod and thrombin infusions lowered the fibrinogen level to 30% or 50% of the initial value due to intravascular coagulation. About 50% of the 125 I fibrinogen was transformed after ancrod exposure into a non-coagulating fraction of fibrinogen derivatives which produces no fibrinolytic decomposition products. (orig./AJ) [de

Coping with socially sensitive topics discourse on interethnic marriages among elderly members of the Serbian minority in Hungary

Directory of Open Access Journals (Sweden)

Ilić Marija

2010-01-01

Full Text Available Drawing on the field research conducted in the Serbian community in Szigetcsép, Hungary, the paper examines interlocutors’ oral discourse on interethnic marriages. Until the Second World War, the Serbs in Hungary, rural communities in particular, mainly practised endogamy. In the post-war era, however, they tended to be among the minority groups with the highest rate of exogamic marriages. Conse­quently, the interviewees established discourse links between “interethnic marriages”, “loss of native language” and “fear of identity loss”. The analytical focus is on the interlocutors’ internal dialogism between the authoritative word of the ancestors and autobiographical assertions.

The flow Rate Accuracy of Elastomeric Infusion Pumps After Repeated Filling.

Science.gov (United States)

Mohseni, Masood; Ebneshahidi, Amin

2014-05-01

One of the frequent applications of elastomeric infusion pumps is postoperative pain management. In daily practice, the disposable pumps get refilled with modified medication combinations in the successive days; although, the accuracy of infusion rates is unknown to clinicians. Our aim was to evaluate the effect of repeated filling on the delivery rate accuracy of an elastomeric pump available in our market. We examined 10 elastomeric infusion pumps (BOT-802, Nanchang Biotek Medical Device Company, China) with 100 mL capacity and nominal flow of 5 mL/h. Each pump was filled for three times, accounting for 30 series of experiments. A microset scaled in mL was used to measure the pump deliveries. Flow profile and reliability of infusion rate were analyzed after repeated use. The mean flow rate in the three series of measurements showed a gradual increase; however, the difference was not statistically significant (5.01 ± 0.07 vs. 5.03 ± 0.06 vs. 5.06 ± 0.08 mL/h; P = 0.81). The percentage of the flow rate error (deviation from 5 mL/h ± 15%) was 100% in the first and second hours of infusion, 96% in the third hour, 60% in the 20th hour and zero percent in the rest of the infusion time. This study indicated that the delivery rate accuracy of elastomeric infusion pumps is preserved after repeated usage. These laboratory findings suggested that elastomeric pumps could be safely refilled in the successive days to provide postoperative analgesia.

Retrospective analysis of detomidine infusion for standing chemical restraint in 51 horses.

Science.gov (United States)

Wilson, D V; Bohart, G V; Evans, A T; Robertson, S; Rondenay, Y

2002-01-01

To assess the effectiveness of a detomidine infusion technique to provide standing chemical restraint in the horse. Retrospective study. Fifty-one adult horses aged 9.5 ± 6.9 years (range 1-23 years) and weighing 575 ± 290.3 kg. Records of horses presented to our clinic over a 3-year period in which a detomidine infusion was used to provide standing chemical restraint were reviewed. Information relating to the types of procedure performed, duration of infusion, drug dosages and adjunct drugs administered was retrieved. Detomidine was administered as an initial bolus loading dose (mean ± SD) of 7.5 ± 1.87 μg kg -1 . The initial infusion rate was 0.6 μg kg -1 minute -1 , and this was halved every 15 minutes. The duration of the infusion ranged from 20 to 135 minutes. Twenty horses received additional detomidine or butorphanol during the procedure. All horses undergoing surgery received local anesthesia or epidural analgesia in addition to the detomidine infusion. A wide variety of procedures were performed in these horses. Detomidine administered by infusion provides prolonged periods of chemical restraint in standing horses. Supplemental sedatives or analgesics may be needed in horses undergoing surgery. An effective method that provides prolonged periods of chemical restraint in standing horses is described. The infusion alone did not provide sufficient analgesia for surgery and a significant proportion of animals required supplemental sedatives and analgesics. Copyright © 2002 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.

Safety and efficacy of gas-forced infusion (air pump) in coaxial phacoemulsification.

Science.gov (United States)

Chaudhry, Prashaant; Prakash, Gaurav; Jacob, Soosan; Narasimhan, Smita; Agarwal, Sunita; Agarwal, Amar

2010-12-01

To evaluate the safety and efficacy of gas-forced infusion (air pump) in uncomplicated coaxial phacoemulsification. Dr. Agarwal's Eye Hospital, Chennai, India. Comparative case series. Specular microscopy and optical coherence tomography were used to analyze the endothelium, central macular thickness (CMT), and peripapillary retinal nerve fiber layer (RNFL) thickness before and approximately 1, 7, 30, and 90 days after coaxial phacoemulsification with (infusion group) or without (control group) gas-forced infusion. Surgical time, surge, phaco energy, irrigation fluid volume, surgical ease, complications, and visual gain in the 2 groups were compared. The mean endothelial cell loss was lower in the infusion group than in the control group (6.98% ± 8.46% [SD] versus 10.54% ± 11.24%; P = .045) and the irrigation/aspiration time significantly shorter (54 ± 39 seconds versus 105 ± 84 seconds; P = .0001). The surgery was rated as easier with gas-forced infusion (scale 1 to 10: mean 8.3 ± 2.1 versus 6.6 ± 1.6; P = .00002). However, the amount of irrigating fluid volume was higher in the infusion group (117 ± 37 mL versus 94 ± 41 mL; P = .003). No surge occurred in the infusion group; it occurred a mean of 3.00 ± 4.16 times in the control group (PGas-forced infusion was safe and effective in controlling surge and increased the safety, ease, and speed of coaxial phacoemulsification. Copyright © 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

Composition of antioxidants and amino acids in Stevia leaf infusions.

Science.gov (United States)

Periche, Angela; Koutsidis, Georgios; Escriche, Isabel

2014-03-01

Stevia, a non-caloric natural sweetener with beneficial properties and considerable antioxidants and amino acids, is increasingly consumed as an infusion. This work evaluates the influence of the conditions (temperature: 50, 70 or 90 °C and time: 1, 5, 20 or 40 min) applied to obtain Stevia infusions, on antioxidants (total phenols, flavonoids and antioxidant activity) and amino acids. The total concentration of the eleven amino acids found was 11.70 mg/g in dried leaves and from 6.84 to 9.11 mg/g per gram of Stevia in infusions. However, infusions showed higher levels of certain amino acids (alanine, asparagine, leucine and proline), and greater values of the three antioxidant parameters in comparison with dry leaves. Temperature had more influence (minimum values at 50 °C and maximum at 90 °C) than time in the case of antioxidants. At 90 °C there were no important increases in the extraction of antioxidant compounds after 5 min; each gram of Stevia had 117 mg trolox (total antioxidant activity), 90 mg gallic acid (total phenols) and 56 mg catechin equivalents (flavonoids). Varying the temperature and time conditions no notable differences were observed in the concentrations of the majority of amino acids. However, the infusion treatment at 90 °C for 5 min was the best, as it gave the highest yield of 8 of the 11 amino acids. Therefore, with respect to the compounds analyzed in this study, the best way to obtain Stevia leaf infusions is the same as the domestic process, almost boiling water for a short time.

Tolerance and diagnostic accuracy of an abbreviated adenosine infusion for myocardial scintigraphy: a randomized, prospective study.

Science.gov (United States)

Treuth, M G; Reyes, G A; He, Z X; Cwajg, E; Mahmarian, J J; Verani, M S

2001-01-01

The objectives of this study were 2-fold: (1) to determine the tolerance of adenosine perfusion tomography with the use of an abbreviated (3-minute) infusion in comparison to the standard (6-minute) infusion, and (2) to assess the relative diagnostic accuracy of a 3-minute adenosine infusion in patients referred for arteriography. An abbreviated adenosine infusion may decrease the frequency and duration of side effects and be a more cost-effective alternative. We prospectively randomized 599 patients undergoing adenosine myocardial perfusion tomography to either a 3-minute or 6-minute adenosine infusion at 140 microg/kg per minute. Among the 599 enrolled patients, 142 subsequently underwent coronary angiography. Patients randomized to the 3-minute adenosine infusion tolerated the procedure better than those randomized to the standard infusion (P <.01). Flushing, headache, neck pain, and atrioventricular block were all significantly less frequent (P <.01) with the abbreviated infusion. Moreover, patients receiving the abbreviated infusion had less hypotension and tachycardia (P <.05). The sensitivity of the test for detection of coronary artery disease was 88% for both the 3- and 6-minute infusions. In patients with abnormal scan results, perfusion defect size was slightly larger in those receiving a 6-minute infusion versus those receiving a 3-minute infusion (P =.05). An abbreviated 3-minute adenosine infusion, in combination with perfusion tomography, has similar sensitivity for detection of coronary artery disease and is better tolerated than the standard 6-minute infusion.

Perisciatic infusion of ropivacaine and analgesia after hallux valgus repair

DEFF Research Database (Denmark)

Zaric, D; Jørgensen, B G; Laigaard, F

2010-01-01

Moderate to severe pain after hallux valgus repair can be successfully treated with a continuous popliteal sciatic nerve block in ambulatory patients. Different anesthesiologists use various infusion rates for this purpose. The aim of this study was to compare the analgesic efficacy of two infusion...

Continuous Intravenous Sub-Dissociative Dose Ketamine Infusion for Managing Pain in the Emergency Department

Directory of Open Access Journals (Sweden)

Jefferson Drapkin

2018-03-01

Full Text Available Introduction: Our objective was to describe dosing, duration, and pre- and post-infusion analgesic administration of continuous intravenous sub-dissociative dose ketamine (SDK infusion for managing a variety of painful conditions in the emergency department (ED. Methods: We conducted a retrospective chart review of patients aged 18 and older presenting to the ED with acute and chronic painful conditions who received continuous SDK infusion in the ED for a period over six years (2010–2016. Primary data analyses included dosing and duration of infusion, rates of pre- and post-infusion analgesic administration, and final diagnoses. Secondary data included pre- and post-infusion pain scores and rates of side effects. Results: A total of 104 patients were enrolled in the study. Average dosing of SDK infusion was 11.26 mg/hr, and the mean duration of infusion was 135.87 minutes. There was a 38% increase in patients not requiring post-infusion analgesia. The average decrease in pain score was 5.04. There were 12 reported adverse effects, with nausea being the most prevalent. Conclusion: Continuous intravenous SDK infusion has a role in controlling pain of various etiologies in the ED with a potential to reduce the need for co-analgesics or rescue analgesic administration. There is a need for more robust, prospective, randomized trials that will further evaluate the analgesic efficacy and safety of this modality across a wide range of pain syndromes and different age groups in the ED.

Infusing Software Engineering Technology into Practice at NASA

Science.gov (United States)

Pressburger, Thomas; Feather, Martin S.; Hinchey, Michael; Markosia, Lawrence

2006-01-01

We present an ongoing effort of the NASA Software Engineering Initiative to encourage the use of advanced software engineering technology on NASA projects. Technology infusion is in general a difficult process yet this effort seems to have found a modest approach that is successful for some types of technologies. We outline the process and describe the experience of the technology infusions that occurred over a two year period. We also present some lessons from the experiences.

Socioeconomic Inequalities in Mental Health of Adult Population: Serbian National Health Survey

Directory of Open Access Journals (Sweden)

Milena Santric Milicevic

2016-02-01

Full Text Available Background: The global burden of mental disorders is rising. In Serbia, anxiety is the leading cause of disability-adjusted life years. Serbia has no mental health survey at the population level. The information on prevalence of mental disorders and related socioeconomic inequalities are valuable for mental care improvement. Aims: То explore the prevalence of mental health disorders and socioeconomic inequalities in mental health of adult Serbian population, and to explore whether age years and employment status interact with mental health in urban and rural settlements. Study Design: Cross-sectional study. Methods: This study is an additional analysis of Serbian Health Survey 2006 that was carried out with standardized household questionnaires at the representative sample of 7673 randomly selected households – 15563 adults. The response rate was 93%. A multivariate logistic regression modeling highlighted the predictors of the 5 item Mental Health Inventory (MHI-5, and of chronic anxiety or depression within eight independent variables (age, gender, type of settlement, marital status and self-perceived health, education, employment status and Wealth Index. The significance level in descriptive statistics, chi square analysis and bivariate and multivariate logistic regressions was set at p<0.05. Results: Chronic anxiety or depression was seen in 4.9% of the respondents, and poor MHI-5 in 47% of respondents. Low education (Odds Ratios 1.32; 95% confidence intervals=1.16-1.51, unemployment (1.36; 1.18-1.56, single status (1.34; 1.23-1.45, and Wealth Index middle class (1.20; 1.08-1.32 or poor (1.33; 1.21-1.47 were significantly related with poor MHI-5. Unemployed persons in urban settlements had higher odds for poormMHI-5 than unemployed in rural areas (0.73; 0.59-0.89. Single (1.50; 1.26-1.78, unemployed (1.39; 1.07-1.80 and inactive respondents (1.42; 1.10-1.83 had a higher odds of chronic anxiety or depression than married individuals, or

Metaphors in terminological collocations in English language and their equivalents in Serbian

Directory of Open Access Journals (Sweden)

Orčić Lidija S.

2017-01-01

Full Text Available The framework of this paper is the theory of conceptual metaphor where metaphor is the transfer of a more concrete source domain into a more abstract target domain. Metaphor is a fundamental human ability to speak about abstract concepts using specific terms where the meaning of a term is transferred to another, thus achieving semantic extensions. Although it was thought that in terminology polysemantic expressions are not desirable, in recent decades this traditional view has been abandoned. Metaphor is used not only as a linguistic decoration in language, but as a means of argumentation. It may be noted that the metaphor, as a universal phenomenon, is also common in business English discourse. The subject of our interest is to investigate collocations made up of those nouns and adjectives, which, according to the Oxford Business English Dictionary for Learners of English, are most frequently used in this field. The main objective of this work is to identify and analyze the source and target domains in metaphors in English collocations that contain these nouns and adjectives, and detect mechanisms applied in translating into Serbian. We categorised metaphors in collocations into four groups. The first group consists of metaphors in which the source domain is expressed with the living beings: inanimate entities are described as if they were alive. In these examples, the personification is used to explain abstract concepts, forces and processes in order to present them in a more understandable way. The second group consists of metaphors in which animals are the source domain and their behavior and characteristics serve as a starting point. In business discourse people and institutions are described with such metaphors. In the third group we included the metaphors based on objects that users are familiar with in everyday life. The fourth group consists of metaphors in which the source domain are natural phenomena. When translating a metaphor we

Intracranial hemodynamics during intravenous infusion of glyceryl trinitrate

DEFF Research Database (Denmark)

Iversen, H.K.; Holm, S.; Friberg, L.

2008-01-01

The mechanisms of glyceryl trinitrate (GTN)-induced headache are not fully elucidated. In this study we administered GTN 0.5 microg/kg/min i.v. for 20 min in six healthy volunteers. Before, during and 60 min after the infusion, we investigated regional cerebral blood flow (rCBF), cerebral blood...... volume (CBV), both estimated with SPECT, and blood flow velocity (BFV) in the middle cerebral artery (MCA), measured with transcranial Doppler. Headache was scored on a numerical verbal rating (0-10) scale. rCBF was unchanged, CBV was slightly increased (13%) during GTN infusion, whereas BFV decreased...... both during (20%) and 60 min (15%) after GTN. Headache was short-lived and maximal during infusion. This discrepancy of time-effect curves for the effect of GTN on headache and dilatation of MCA indicates that MCA is most likely not the primary source of pain in GTN-induced headache. The time...

Glucagon infusion increases rate of purine synthesis de novo in rat liver

International Nuclear Information System (INIS)

Itakura, Mitsuo; Maeda, Noriaki; Tsuchiya, Masami; Yamashita, Kamejiro

1987-01-01

Based on the parallel increases of glucagon, the second peak of hepatic cAMP, and the rate of purine synthesis de novo in the prereplicative period in regenerating rate liver after a 70% hepatectomy, it was hypothesized that glucagon is responsible for the increased rate of purine synthesis de novo. To test this hypothesis, the effect of glucagon or dibutyryl cAMP infusion on the rate of purine synthesis de novo in rat liver was studied. Glucagon infusion but not insulin or glucose infusion increased the rate of purine synthesis de novo, which was assayed by [ 14 C]glycine or [ 14 C]formate incorporation, by 2.7- to 4.3-fold. Glucagon infusion increased cAMP concentrations by 4.9-fold and 5-phosphoribosyl-1-pyrophosphate concentrations by 1.5-fold in liver but did not change the specific activity of amidophosphoribosyltransferase or purine ribonucleotide concentrations. Dibutyryl cAMP infusion also increased the rate of purine synthesis de novo by 2.2- to 4.0-fold. Because glucagon infusion increased the rate of purine synthesis de novo in the presence of unchanged purine ribonucleotide concentrations, it is concluded that glucagon after infusion or in animals after a 70% hepatectomy is playing an anabolic role to increase the rate of purine synthesis de novo by increasing cAMP and 5-phosphoribosyl-1-pyrophosphate concentrations

Effects of adenosine infusion into renal interstitium on renal hemodynamics

International Nuclear Information System (INIS)

Pawlowska, D.; Granger, J.P.; Knox, F.G.

1987-01-01

This study was designed to investigate the hemodynamic effects of exogenous adenosine in the interstitium of the rat kidney. Adenosine or its analogues were infused into the renal interstitium by means of chronically implanted capsules. In fusion of adenosine decreased glomerular filtration rate (GFR) from 0.81 +/- 0.06 to 0.37 +/- 0.06 ml/min while having no effect on renal blood flow (RBF). The metabolically stable analogue, 2-chloradenosine (2-ClAdo), decreased GFR from 0.73 +/- 0.07 to 021 +/- 0.06 ml/min. Interstitial infusion of theophylline, an adenosine receptor antagonist, completely abolished the effects of adenosine and 2-ClAdo on GFR. The distribution of adenosine, when infused into the renal interstitium, was determined using radiolabeled 5'-(N-ethyl)-carboxamidoadenosine (NECA), a metabolically stable adenosine agonist. After continuous infusion, [ 3 H]NECA was distributed throughout the kidney. The effects of NECA to reduce GFR were similar to those of adenosine and 2-ClAdo. They conclude that increased levels of adenosine in the renal interstitium markedly decrease GFR without affecting RBF in steady-state conditions. The marked effects of adenosine agonists during their infusion into the renal interstitium and the complete blockade of these effects by theophylline suggest an extracellular action of adenosine

Reassessment of primed constant-infusion tracer method to measure urea kinetics

International Nuclear Information System (INIS)

Jahoor, F.; Wolfe, R.R.

1987-01-01

The validity of the primed constant-infusion tracer technique to make short-term measurements of urea production rates (R/sub a/) in humans in a physiological steady state and during disruption of steady state was evaluated. Four subjects received a primed constant infusion (P/I = 560 min) of [ 13 C]urea for 8 h. A plateau in urea enrichment was reached after 2 h and maintained throughout. When [ 13 C]- and [ 18 O]urea were simultaneously infused into four subjects at P/I ratios of 560:1 and 360:1, respectively, both tracers reached plateau enrichment at the same time (2-4 h). The enrichment at plateau was a function of the infusion rate rather than the priming dose, and calculated urea R/sub a/ was the same with either prime. In five additional experiments the technique responded acutely to a physiological perturbation (alanine infusion) in a dose-dependent manner. The results confirm that this technique is appropriate for short-term measurements of urea R/sub a/, and the requirement for accuracy in estimating the priming dose is not impractically stringent

Hippocampal Infusion of Zeta Inhibitory Peptide Impairs Recent, but Not Remote, Recognition Memory in Rats

Directory of Open Access Journals (Sweden)

Jena B. Hales

2015-01-01

Full Text Available Spatial memory in rodents can be erased following the infusion of zeta inhibitory peptide (ZIP into the dorsal hippocampus via indwelling guide cannulas. It is believed that ZIP impairs spatial memory by reversing established late-phase long-term potentiation (LTP. However, it is unclear whether other forms of hippocampus-dependent memory, such as recognition memory, are also supported by hippocampal LTP. In the current study, we tested recognition memory in rats following hippocampal ZIP infusion. In order to combat the limited targeting of infusions via cannula, we implemented a stereotaxic approach for infusing ZIP throughout the dorsal, intermediate, and ventral hippocampus. Rats infused with ZIP 3–7 days after training on the novel object recognition task exhibited impaired object recognition memory compared to control rats (those infused with aCSF. In contrast, rats infused with ZIP 1 month after training performed similar to control rats. The ability to form new memories after ZIP infusions remained intact. We suggest that enhanced recognition memory for recent events is supported by hippocampal LTP, which can be reversed by hippocampal ZIP infusion.

Responses to Starch Infusion on Milk Synthesis in Low Yield Lactating Dairy Cows

Directory of Open Access Journals (Sweden)

Yang Zou

2015-09-01

Full Text Available The effect of starch infusion on production, metabolic parameters and relative mRNA abundance was investigated in low yield lactating cows from 86 days in milk. Six Holstein cows fitted with permanent ruminal cannulas were arranged into one of two complete 3×3 Latin squares and infused with a starch solution containing 800 grams starch for 16 days. The three treatments were: i ruminal and abomasal infusion with water (Control; ii ruminal infusion with cornstarch solution and abomasal infusion with water (Rumen; iii ruminal infusion with water and abomasal infusion with cornstarch solution (Abomasum. There were no significant differences (p>0.05 among the three treatments with low yield lactating cows in feed and energy intake, milk yield and composition, plasma metabolism, or even on gene expression. However, cows receiving starch through rumen performed better than directly through the abomasum during the glucose tolerance test procedure with a higher area under the curve (AUC; p = 0.08 and shorter half-time (t1/2; p = 0.11 of plasma insulin, therefore, it increased glucose disposal, which stated a lipid anabolism other than mobilization after energy supplementation. In conclusion, extra starch infusion at concentration of 800 g/d did not enhance energy supplies to the mammary gland and improve the lactating performance in low yield lactating cows.

Ejection experience in Serbian air force, 1990-2010

Directory of Open Access Journals (Sweden)

Pavlović Miroslav

2014-01-01

Full Text Available Background/Aim. Ejection injuries are the problem for air forces. The present risk for injuries is still too high, approximately 30-50%. This study was an effort to determine factors responsible for and contributing to injuries in the Serbian Air Force (SAF in the last two decades. Methods. All ejection cases in the SAF between 1990 and 2010 were analyzed. The collected data were: aircraft type, ejection seat generation, pilots ´ age and experience, causes of ejection, aeronautical parameters, the condition of aircraft control and types of injuries. For ease of comparison the U.S. Air Force Safety Regulation was used to define of major injuries: hospitalization for 5 days or more, loss of consciousness for over 5 min, bone fracture, joint dislocation, injury to any internal organ, any third-degree burn, or second-degree burn over 5% of the body surface area. Results. There were 52 ejections (51 pilots and 1 mechanic on 44 airplanes. The ejected persons were from 22 to 46 years, average 32 years. Major injuries were present in 25.49% cases. Of all the ejected pilots 9.61% had fractures of thoracic spine, 11.53% fractures of legs, 3.48% fractures of arms. Of all major injuries, fractures of thoracic spine were 38.46%. None of the pilots had experienced ejection previously. Conclusion. Our results suggest to obligatory take preventive measures: magnetic resonance imaging (MRI scan must be included in the standard pilot selection procedure and procedure after ejection. Physical conditioning of pilots has to be improved. Training on ejection trainer has to be accomplished, too.

Software Engineering Technology Infusion Within NASA

Science.gov (United States)

Zelkowitz, Marvin V.

1996-01-01

Abstract technology transfer is of crucial concern to both government and industry today. In this paper, several software engineering technologies used within NASA are studied, and the mechanisms, schedules, and efforts at transferring these technologies are investigated. The goals of this study are: 1) to understand the difference between technology transfer (the adoption of a new method by large segments of an industry) as an industry-wide phenomenon and the adoption of a new technology by an individual organization (called technology infusion); and 2) to see if software engineering technology transfer differs from other engineering disciplines. While there is great interest today in developing technology transfer models for industry, it is the technology infusion process that actually causes changes in the current state of the practice.

Carbon Nanotube Infused Launch Vehicle Structures

Data.gov (United States)

National Aeronautics and Space Administration — For the past 5 years Orbital ATK has been investing in, prototyping, and testing carbon nanotube infused composite structures to evaluate their impact on launch...

Antioxidant capacity and polyphenolic content of blueberry (Vaccinium corymbosum L.) leaf infusions.

Science.gov (United States)

Piljac-Zegarac, J; Belscak, A; Piljac, A

2009-06-01

Antioxidant capacity and polyphenolic content of leaf infusions prepared from six highbush blueberry cultivars (Vaccinium corymbosum L.), one wild lowbush blueberry cultivar (Vaccinium myrtillus L.), and one commercially available mix of genotypes were determined. In order to simulate household tea preparation conditions, infusions were prepared in water heated to 95 degrees C. The dynamics of extraction of polyphenolic antioxidants were monitored over the course of 30 minutes. Extraction efficiency, quantified in terms of the total phenol (TP) content, and antioxidant capacity of infusions, evaluated by the ferric reducing antioxidant power (FRAP) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging assays, were compared with cultivar type and extraction time. The 30-minute infusions exhibited the highest TP content and antioxidant capacity according to all three assays. Wild blueberry infusion had the highest TP content (1,879 mg/L gallic acid equivalents [GAE]) and FRAP values (20,050 microM). The range of TP values for 30-minute infusions was 394-1,879 mg/L GAE with a mean of 986 mg/L GAE across cultivars; FRAP values fell between 3,015 and 20,050 microM with a mean of 11,234 microM across cultivars. All 30-minute infusions exhibited significant scavenging capacity for DPPH(*) and ABTS(*+) radicals, comparable to different concentrations of catechin, gallic acid, and 6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid. Overall, tested infusions showed significant reducing capacity as well as radical scavenging potential, which places blueberry leaf tea high on the list of dietary sources of antioxidants.

The efficacy of intraperitoneal saline infusion for percutaneous radiofrequency ablation for hepatocellular carcinoma

International Nuclear Information System (INIS)

Park, Soo Young; Tak, Won Young; Jeon, Seong Woo; Cho, Chang Min; Kweon, Young Oh; Kim, Sung Kook; Choi, Yong Hwan

2010-01-01

Objective: To evaluated the efficacy and safety of radiofrequency ablation (RFA) with intraperitoneal saline infusion. Background: Ultrasound-guided RFA is not always feasible due to the tumor location, possible adjacent tissue damage or poor sonographic identification. Patients and methods: Ultrasound-guided RFA with intraperitoneal saline infusion was performed in 116 patients between June 2001 and March 2008. Results: The overall technical feasibility of the intraperitoneal saline infusions was 90.5% (105 patients). The purposes of the intraperitoneal saline infusion were achieved in 100 patients (86.2%) by visualizing the tumor located in hepatic dome (47 patients), prevent adjacent organ damage (42 patients) and withdrawing overlying omentum (10 patients). Complete ablation of tumor was accomplished in 102 patients (87.9%). Complications associated with the treatment occurred in seven patients (6.0%). There was no case of adverse event directly related to intraperitoneal saline infusion. Conclusions: Intraperitoneal saline infusion is an effective and safe procedure that can be used to overcome the current limitations of ultrasound-guided RFA.

Saline Infusion Markedly Reduces Impedance and Improves Efficacy of Pulmonary Radiofrequency Ablation

International Nuclear Information System (INIS)

Gananadha, Sivakumar; Morris, David Lawson

2004-01-01

Radiofrequency ablation (RFA) is a relatively new technique that has been investigated for the treatment of lung tumors. We evaluated for the first time the in vivo use of saline infusion during radiofrequency ablation of sheep lung. We performed RFA on 5 sheep using open and closed chest RFA and the RITA starburst XL and Xli probes using saline infusion with the Xli probe. The impedance and volume of ablation were compared. A total of 16 ablations were produced, 5 percutaneously and 11 open. The impedance during percutaneous and open RFA without saline infusion was 110 ± 16.2 and 183.3 ± 105.8 O, respectively. With the saline infusion the impedance was 71.3 ± 22O and 103.6 ± 37.5O. The effect of this was a significantly larger volume of ablation using the saline infusion during percutaneous RFA (90.6 ± 23 cm 3 vs 10.47 ± 2.9 cm 3 , p = 0.01) and open RFA (107.8 ± 25.8 cm 3 vs 24.9 ± 19.3 cm 3 , p = 0.0002). Saline infusion during RFA is associated with lower impedance, higher power delivery and larger lesion size.

Saline Infusion Markedly Reduces Impedance and Improves Efficacy of Pulmonary Radiofrequency Ablation

International Nuclear Information System (INIS)

Gananadha, Sivakumar; Morris, David Lawson

2004-01-01

Radiofrequency ablation (RFA) is a relatively new technique that has been investigated for the treatment of lung tumors. We evaluated for the first time the in vivo use of saline infusion during radiofrequency ablation of sheep lung. We performed RFA on 5 sheep using open and closed chest RFA and the RITA starburst XL and Xli probes using saline infusion with the Xli probe. The impedance and volume of ablation were compared. A total of 16 ablations were produced, 5 percutaneously and 11 open. The impedance during percutaneous and open RFA without saline infusion was 110 ± 16.2 and 183.3 ± 105.8 O, respectively. With the saline infusion the impedance was 71.3 ± 22O and 103.6 ± 37.5O. The effect of this was a significantly larger volume of ablation using the saline infusion during percutaneous RFA (90.6 ± 23 cm 3 vs 10.47 ± 2.9 cm 3 , p = 0.01) and open RFA (107.8 ± 25.8 cm 3 vs 24.9 ± 19.3 cm 3 , p = 0.0002). Saline infusion during RFA is associated with lower impedance, higher power delivery and larger lesion size

[Methods of preventing phlebitis induced by infusion of fosaprepitant].

Science.gov (United States)

Kohno, Emiko; Kanematsu, Sayaka; Okazaki, Satoshi; Ogata, Makoto; Kanemitsu, Meiko; Yamashita, Hiromi; Syuntou, Kaori; Sekita, Masako; Nishioka, Ryoko; Yoshida, Hideyuki

2015-03-01

At our hospital, we use aprepitant for nausea and vomiting when administering highly emetic anticancer agents, according to "Guidelines for the Appropriate Use of Antiemetic Agents" given by the Japan Society of Clinical Oncology. We initiated the intravenous administration of fosaprepitant for better compliance compared with aprepitant; however, we observed phlebitis after the infusion of fosaprepitant. Therefore, we investigated measures to reduce phlebitis associated with the infusion of fosaprepitant. For the first premedication, fosaprepitant (150 mg) was dissolved in 100 mL of saline and administered for 30 minutes; 1 of 2 patients showed grade 4 phlebitis. For the modified premedication, fosaprepitant, dexamethasone, and 5- HT(3) antagonist were dissolved in 100 mL of saline and administered for 30 minutes. The modified premedication was administered to a total of 27 patients; 5 patients developed mild phlebitis (grade 1), but infusion could be continued by treating their phlebitis with a hot pack. We used a combination of dexamethasone and 5-HT(3) antagonist with fosaprepitant as a modified premedication in order to avoid drug-induced vascular damage, which resulted in the pH decreasing to 6.20-7.55 (close to neutral) and a shorter infusion time.

Online feedback-controlled renal constant infusion clearances in rats.

Science.gov (United States)

Schock-Kusch, Daniel; Shulhevich, Yury; Xie, Qing; Hesser, Juergen; Stsepankou, Dzmitry; Neudecker, Sabine; Friedemann, Jochen; Koenig, Stefan; Heinrich, Ralf; Hoecklin, Friederike; Pill, Johannes; Gretz, Norbert

2012-08-01

Constant infusion clearance techniques using exogenous renal markers are considered the gold standard for assessing the glomerular filtration rate. Here we describe a constant infusion clearance method in rats allowing the real-time monitoring of steady-state conditions using an automated closed-loop approach based on the transcutaneous measurement of the renal marker FITC-sinistrin. In order to optimize parameters to reach steady-state conditions as fast as possible, a Matlab-based simulation tool was established. Based on this, a real-time feedback-regulated approach for constant infusion clearance monitoring was developed. This was validated by determining hourly FITC-sinistrin plasma concentrations and the glomerular filtration rate in healthy and unilaterally nephrectomized rats. The transcutaneously assessed FITC-sinistrin fluorescence signal was found to reflect the plasma concentration. Our method allows the precise determination of the onset of steady-state marker concentration. Moreover, the steady state can be monitored and controlled in real time for several hours. This procedure is simple to perform since no urine samples and only one blood sample are required. Thus, we developed a real-time feedback-based system for optimal regulation and monitoring of a constant infusion clearance technique.

Radiation resistance of microorganisms on unsterilized infusion sets

DEFF Research Database (Denmark)

Christensen, E. Ahrensburg; Kristensen, H.; Hoborn, J.

1991-01-01

Three different methods were used for detecting and isolating microorganisms with high radiation resistance from the microbial contamination on infusion sets prior to sterilization. By all three methods, microorganisms with a radiation resistance high enough to be a critical factor in a steriliza......Three different methods were used for detecting and isolating microorganisms with high radiation resistance from the microbial contamination on infusion sets prior to sterilization. By all three methods, microorganisms with a radiation resistance high enough to be a critical factor...

Effect of transdermal glyceryl trinitrate and anti-inflammatory gel in infusion phlebitis.

Science.gov (United States)

Cökmez, Atilla; Gür, Serhat; Genç, Hüdai; Deniz, Sümer; Tarcan, Ercüment

2003-10-01

Phlebitis is the commonest complication of intravenous infusion. It has been suggested that it is initiated by venoconstriction at the infusion site, hence treatment with a vasodilator may reduce its incidence. A prospective controlled study was carried out on the effect of transdermal glyceryl trinitrate (GTN) and topical anti-inflammatory gel (non-steroidal anti-inflammatory drug; NSAID) on the survival of peripheral intravenous infusion in 386 patients. A total of 34.9% (43 out of 123) of the infusions failed in the control group compared with 14.1% (18 out of 127) in the NSAID group (P NSAI gel and GTN but NSAI gel is more effective than GTN.

ARTICULATION DISORDERS IN SERBIAN LANGUAGE IN CHILDREN WITH SPEECH PATHOLOGY.

Science.gov (United States)

Dmitrić, Tanja; Veselinović, Mila; Mitrović, Slobodan M

2015-01-01

Articulation is the result of speech organs and it means clean, clear and distinct pronunciation of voices in words. A prospective study included 24 children between 5 and 15 years of age, of both sexes. All children were monolingual, Serbian being their native language. The quality of articulation was tested with Triage articulation test. Neither omission nor distortion of plosives was observed in any of them, whereas substitution of plosives occurred in 12% of patients. Omission of affricates was not observed in any of the subjects, but substitution and distortion occurred in 29%, and 76% of subjects, respectively. Omission of fricatives was found in 29% subjects, substitution in 52%, and distortion in 82% of subjects. Omission and distortion of nasals was not recorded in any of the subjects, and substitution occurred in 6% of children. Omission of laterals was observed in 6%, substitution in 46% and distortion in 52% of subjects with articulation disorders. Discussion and Articulation disorders were observed not only in children diagnosed with dyslalia but in those with dysphasia and stuttering as well. Children with speech disorders articulate vowels best, then nasals and plosives. Articulation of fricatives and laterals was found to be most severely deviated, including all three disorders, i.e. substitution, omission and distortion. Spasms of speech muscles and vegetative reactions were also observed in this study, but only in children with stuttering.

Gallbladder ejection fraction (GBEF): after 0.02(G/KG cholecystokinin (CCK) infusion over 30 minutes in patients with a low probability of gallbladder disease

International Nuclear Information System (INIS)

Docherty, P.; Micallef, L.; Gruenewald, S.; Larcos, G.

2003-01-01

Full text: Recent literature suggests that an infusion of 0.02 (g/Kg of CCK results in a narrower range of normal GBEF than an infusion 0.01(g/Kg of. Our aim was to investigate the effect of a 30-minutes infusion of 0.02 (g/Kg, in patients with a low probability of gallbladder disease. Sixty patients presenting with abdominal symptoms were referred to West mead Medical Imaging over a 9-month period for DISIDA biliary scans. 1-minute dynamic images were collected over 90 minutes. The CCK infusion was commenced when the gallbladder was well filled. GBEF was calculated from background corrected time activity curves over the gallbladder. Sixteen patients were excluded because of previous cholecystectomy or known gallbladder disease. Thirty-three patients were considered to have a low probability of gallbladder disease after final diagnoses were obtained from referring doctors. The mean GBEF for this group was 65.6%, SD 17.2 with a mean range 28-98% compared with mean 56.9%, SD 18.1 with a mean range 21-85% of our previous study using 0.01(gCCK. Females exhibited lower GBEFs than males while females under 50 gave the lowest mean. We concluded that the higher dose infusion causes more complete gallbladder emptying, and that there is a difference in GBEF between males and females of different ages. We question the validity of the same 'Normal' range being applied to both genders and all age groups. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

Blood-brain barrier opening by isotonic saline infusion in normotensive and hypertensive animals

Energy Technology Data Exchange (ETDEWEB)

Rapoport, S I [Baltimore City Hospitals, MD (USA)

1978-01-01

The blood-brain barrier to intravascular Evans blue-albumin was opened in monkeys and rabbits by infusing isotonic saline for 15 s into the common carotid artery, when the external carotid was clamped temporarily and the lingual was catheterized for measuring pressure. Barrier opening correlated better with infusion pressure than with infusion rate, and occurred at carotid artery pressures above 170 mmHg. Systematic hypertension induced by Aramine increased barrier vulnerability by causing a higher net carotid artery pressure to be attained at a given infusion rate.

Developing a System for Integraded Automatic Control of Mutiple Infusion Pumps : The Multiplex infusion system

NARCIS (Netherlands)

Doesburg, Frank

2013-01-01

Most errors in ICUs are related to intravenous (IV) therapy. Previous studies suggested that hard to operate infusion pumps and the high cognitive workload for ICU nurses contribute to these errors. Conventional IV therapy requires separate lumens for incompatible IV drugs. This often requires the

Clinical assessment of first pass radionuclide ventriculography after dipyridamole infusion in patients with coronary artery disease

International Nuclear Information System (INIS)

Kanaya, Tohru; Tono-oka, Ichiro; Satoh, Satoshi; Yamaguchi, Yoshiko; Hoshi, Hikaru; Ikeda, Kozue; Tsuiki, Kai; Yasui, Shoji; Komatani, Akio

1986-01-01

First pass radionuclide ventriculography (RNV) was performed after dipyridamole (D) infusion in 33 patients with coronary artery disease (CAD) and 15 normal volunteers. RNV findings after D infusion were compared with those of conventional exercise RNV and body surface ECG mapping (MAP). For patients with multiple vessel disease, left ventricular ejection fraction (LVEF) was significantly lower after D infusion than at rest. Wall motion abnormality (WMA) sites induced by D infusion were well coincident with those induced by exercise. Pressure rate product at exercise was significantly higher than that after D infusion, suggesting the different mechanism of the occurrence of WMA after D infusion and at exercise. The incidence of ischemic reaction tended to be higher after D infusion than at exercise in 25 patients with CAD. There was negative correlation between ST depression on MAP after D infusion and LVEF on RNV after D infusion. This RNV after D infusion can be used as a supplement tool to conventional exercise RNV in the evaluation of the degree of coronary artery lesions and preserved left ventricular function. (Namekawa, K.)

Reversal of behavioral depression by infusion of an alpha-2 adrenergic agonist into the locus coeruleus.

Science.gov (United States)

Simson, P G; Weiss, J M; Hoffman, L J; Ambrose, M J

1986-04-01

This experiment demonstrated that behavioral depression produced by exposure of rats to strong uncontrollable shocks could be reversed by infusion of the alpha-2 adrenergic agonist clonidine into the region of the locus coeruleus (LC). A 20-min infusion, through bilateral cannulae, into the locus coeruleus of clonidine, piperoxane (alpha-2 antagonist) or inactive vehicle (0.85% saline), was given beginning 70 min after the animals were removed from the stress situation. The dose and volume of drug given in the infusion (0.16 microgram/microliter, 0.1 microliter/min) had been previously shown to produce effects specific to the locus coeruleus (Weiss, Simson, Hoffman, Ambrose, Cooper and Webster, 1986; Neuropharmacology 25: 367-384). At the conclusion of the infusion, active behavior of animals was measured in a 15-min swim test. Results showed that stressed animals infused with vehicle exhibited significantly less active behavior in the swim test than did non-stressed animals infused with vehicle, thereby showing the usual behavioral depression seen after exposure to an uncontrollable stress. Stressed animals infused with clonidine showed no difference in active behavior in comparison to non-stressed animals infused with vehicle and showed significantly more activity than did the stressed animals infused with vehicle. Stressed animals infused with piperoxane showed no significant difference in activity in comparison to the stressed animals infused with vehicle and were significantly less active than either the non-stressed animals infused with vehicle or the stressed animals infused with clonidine. Thus, infusion into the locus coeruleus of the alpha-2 agonist clonidine, but not the alpha-2 antagonist piperoxane, eliminated behavioral depression.(ABSTRACT TRUNCATED AT 250 WORDS)

Quality-improvement analytics for intravenous infusion pumps.

Science.gov (United States)

Skledar, Susan J; Niccolai, Cynthia S; Schilling, Dennis; Costello, Susan; Mininni, Nicolette; Ervin, Kelly; Urban, Alana

2013-04-15

The implementation of a smart-pump continuous quality-improvement (CQI) program across a large health system is described, with an emphasis on key metrics for outcomes analyses and program refinement. Three years ago, the University of Pittsburgh Medical Center health system launched a CQI initiative to help ensure the safe use of 6000 smart pumps in its 14 inpatient facilities. A centralized team led by pharmacists is responsible for the retrieval and interpretation of smart-pump data, which is continuously transmitted to a main server. CQI findings are regularly posted on the health system's interdisciplinary intranet. Monitored metrics include rates of compliance with preprogrammed infusion limits, the top 20 drugs involved in alerts, drugs associated with alert-override rates of ≥90%, numbers of alerts by infusion type, nurse responses to alerts, and alert rate per drug library update. Based on the collected CQI data and site-specific requests, four systemwide updates of the smart-pump drug library were performed during the first 18 months of the program, reducing "nuisance alerts" by about 10% per update cycle and enabling targeted interventions to reduce rapid-infusion errors, other adverse drug events (ADEs), and pump-programming workarounds. Over one 12-month period, bedside alerts prompted nurses to reprogram or cancel continuous infusions an average of 400 times per month, potentially averting i.v. medication ADEs. A smart-pump CQI program is an effective tool for enhancing the safety of i.v. medication administration. The ongoing refinement of the drug library through the development and implementation of key interventions promotes the growth and sustainability of the smart-pump initiative systemwide.

"I’m a poor lonesome cowboy and a long way from home…": Serbian Documentary Films about Guest Workers

Directory of Open Access Journals (Sweden)

Marija Krstić

2016-02-01

Full Text Available In this paper I will analyze Serbian documentary films about guest workers dating from the last decade of the 20th and the first decade of the 21st century, using the perspective of visual anthropology. I question the popular cultural notions about guest workers in films Весеље у Ждрелу (A Celebration in Zdrelo by author Kamenko Katic, Звона позне јесени (The Bells of Late Autumn by author Zoran Milenovic, Кад је Милорад удавао ћерку (When Milorad Gave His Daughter in Marriage by author Vladimir Milisavljevic, Странац тамо, странац овде (A Foreigner There, a Foreigner Here by author Sandra Mandic and 242 метра живота (242 Meters of Life by author Novica Savic. The films deal with a number of issues: the economic aspects of guest workers’ lives, their liminal character, the issues of the second and third generations of guest workers, going away "temporarily" to work, and religious rituals. Even though the films were made recently, they all follow the lives of Vlach and Serbian, or rather Yugoslav guest workers who left to find temporary work abroad in Western Europe in the 1960’s and 1970’s. This serves the purpose of avoiding to deal with contemporary reasons for emigrating from Serbia and thus the possible critiques of current regimes or policies in power at the time the films were made.

Using miniature osmotic infusion pumps to maintain tritiated thymidine exposure to cells in culture

International Nuclear Information System (INIS)

Neely, J.E.; Hake, D.A.

1982-01-01

To provide a constant level of tracer doses of tritiated thymidine to cultured cells during continuous infusion, miniature osmotic infusion pumps were used to provide replacement thymidine. By determining the loss of isotope from the media during nonreplacement, the rate of constant infusion replacement to maintain thymidine levels was calculated. The replacement rates were similar for the three cell lines examined and allowed a standard osmotic pump infusion

Blood-brain barrier opening by isotonic saline infusion in normotensive and hypertensive animals

International Nuclear Information System (INIS)

Rapoport, S.I.

1978-01-01

The blood-brain barrier to intravascular Evans blue-albumin was opened in monkeys and rabbits by infusing isotonic saline for 15 s into the common carotid artery, when the external carotid was clamped temporarily and the lingual was catheterized for measuring pressure. Barrier opening correlated better with infusion pressure than with infusion rate, and occurred at carotid artery pressures above 170 mmHg. Systematic hypertension induced by Aramine increased barrier vulnerability by causing a higher net carotid artery pressure to be attained at a given infusion rate. (Auth.)

Boron biodistribution in Beagles after intravenous infusion of 4-dihydroxyborylphenylalanine-fructose complex

International Nuclear Information System (INIS)

Kulvik, M.E.; Vaehaetalo, J.K.; Benczik, J.; Snellman, M.; Laakso, J.; Hermans, R.; Jaerviluoma, E.; Rasilainen, M.; Faerkkilae, M.; Kallio, M.E.

2004-01-01

Boron biodistribution after intravenous infusion of 4-dihydroxyborylphenylalanine-fructose (BPA-F) complex was investigated in six dogs. Blood samples were evaluated during and following doses of 205 and 250 mg/kgbw BPA in a 30 min infusion, and 500 mg/kgbw in a 1 h infusion. Samples from whole blood, urine, brain and other organs were analysed for boron content after varying times following the onset of infusion. The whole blood boron concentrations declined from 27 to 8.4 ppm over the period of 39-165 min after the onset of infusion and the levels increased from 1.9 to 12 ppm in the grey matter of the brain over the same period. The boron concentrations in whole blood decreased steadily, whereas the boron values in brain tissue rose steadily with time. It was concluded that whole blood boron concentrations do not seem to reflect accurately the boron concentration in brain tissue at respective time points

Anaphylaxis after intravenous infusion of dexketoprofen trometamol

Directory of Open Access Journals (Sweden)

Sertac Guler

2016-09-01

Full Text Available Dexketoprofen trometamol (DT, a nonsteroidal anti-inflammatory drug, is a highly water-soluble salt and active enantiomer of rac-ketoprofen. Its parenteral form is commonly used for acute pain management in emergency departments of our country. Side effects such as diarrhea, indigestion, nausea, stomach pain, and vomiting may be seen after the use of DT. Anaphylactic shock (AS secondary to infusion of DT is very rare and, to our knowledge, it is the first case report describing this side effect. This case report was presented to emphasize that AS may be seen after the use of DT. Keywords: Anaphylactic shock, Dexketoprofen trometamol, Intravenous infusion (MeSH database

Continuous subcutaneous insulin infusion in diabetes: patient populations, safety, efficacy, and pharmacoeconomics

OpenAIRE

Pozzilli, Paolo; Battelino, Tadej; Danne, Thomas; Hovorka, Roman; Jarosz?Chobot, Przemyslawa; Renard, Eric

2015-01-01

Summary The level of glycaemic control necessary to achieve optimal short?term and long?term outcomes in subjects with type 1 diabetes mellitus (T1DM) typically requires intensified insulin therapy using multiple daily injections or continuous subcutaneous insulin infusion. For continuous subcutaneous insulin infusion, the insulins of choice are the rapid?acting insulin analogues, insulin aspart, insulin lispro and insulin glulisine. The advantages of continuous subcutaneous insulin infusion ...

Tumor and liver drug uptake following hepatic artery and portal vein infusion

International Nuclear Information System (INIS)

Sigurdson, E.R.; Ridge, J.A.; Kemeny, N.; Daly, J.M.

1987-01-01

Anatomic dye injection studies of the blood supply of colorectal hepatic metastases suggest that tumors are supplied predominantly by the hepatic artery. Using 13 N amino acids with dynamic gamma camera imaging in patients with colorectal hepatic metastases, it has been shown that hepatic artery infusion results in a significantly greater nutrient delivery to tumor compared with portal vein infusion. However, direct measurements of drug levels in tumor following hepatic artery and portal vein infusion in humans have not previously been reported. Patients with metastatic colorectal cancer confined to the liver received fluorodeoxyuridine (FUdR) through the hepatic artery or through the portal vein. All patients had previously failed systemic chemotherapy. Five patients with hepatic artery catheters were matched (by age, serum lactic dehydrogenase levels, percent hepatic replacement, and tumor size) with five patients with portal vein catheters. At operation, 3 H-FUdR (1 microCi/kg) and /sup 99m/Tc-macroaggregated albumin (MAA) (6 mCi) were injected into the hepatic artery or portal vein. Liver and tumor biopsies were obtained two and five minutes later. 3 H and /sup 99m/Tc were measured per gram tissue by scintillation and gamma counting. The mean liver levels following hepatic artery infusion (23.9 +/- 11.4 nmol/g) and portal vein infusion (18.4 +/- 14.5 nmol/g) did not differ. However, the mean tumor FUdR level following hepatic artery infusion was 12.4 +/- 12.2 nmol/g, compared with a mean tumor FUdR level following portal vein infusion of 0.8 +/- 0.7 nmol/g (P less than .01). This low level of tumor drug uptake after portal vein infusion of FUdR predicts minimal tumor response to treatment via this route. Thus, regional chemotherapy for established colorectal hepatic metastases should be administered through the hepatic artery

Role of executive agencies for energy efficiency with a view on activities of Serbian Energy Efficiency Agency

Directory of Open Access Journals (Sweden)

Kovačić Bojan J.

2012-01-01

Full Text Available Many countries, particularly in Europe, have executive energy efficiency agencies at national, regional and local levels that are organized in different ways. For all of them, it is common that there are existing strategic needs in their countries for enhancement of conditions and measures for rational use of energy and fuels. Serbian Energy Efficiency Agency was established in 2002 within the reform of the energy sector in Serbia and its current status was defined in 2004 by the Energy Law. It contributes to the improvement of social responsibility towards energy in all structures of the state and society, by proposing energy efficiency incentives, promoting importance of energy efficiency, as well as by managing energy efficiency and renewable energy programs and projects.

Kidney function in normal man during short-term growth hormone infusion

DEFF Research Database (Denmark)

Parving, H H; Noer, I; Mogensen, C E

1978-01-01

Kidney function was studied in 9 normal males before and during a 2 h growth hormone (GH) infusion of 50 ng/kg/min. The following variables were measured during each 20 min clearance period: glomerular filtration rate, GFR, effective renal plasma flow, RPF (steady state infusion technique...... with urinary collections using [125I]iothalamate and [131I]iodohippurate), and urinary albumin and beta2-microglobulin excretion rates (radioimmunoassays). The GH infusion resulted in a 10-fold increase in plasma GH concentration. All the above mentioned variables remained practically unchanged during...... the infusion except for a small (-5%) but significant decrease in renal plasma flow (P less than 0.01). Our negative results contrast to the findings of increased GFR and RPF during prolonged GH administration and suggest that GH requires several hours or days for its renal effects to become manifest....

Effect of perioperative insulin infusion on surgical morbidity and mortality

DEFF Research Database (Denmark)

Gandhi, Gunjan Y; Murad, M Hassan; Flynn, Errol David

2008-01-01

To conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of perioperative insulin infusion on outcomes important to patients.......To conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the effect of perioperative insulin infusion on outcomes important to patients....

Propofol Infusion Syndrome: A Retrospective Analysis at a Level 1 Trauma Center

Directory of Open Access Journals (Sweden)

James H. Diaz

2014-01-01

Full Text Available Objectives. The propofol infusion syndrome (PRIS, a rare, often fatal, condition of unknown etiology, is defined by development of lipemic serum, metabolic acidosis, rhabdomyolysis, hepatomegaly, cardiac arrhythmias, and acute renal failure. Methods. To identify risk factors for and biomarkers of PRIS, a retrospective chart review of all possible PRIS cases during a 1-year period was conducted at a level 1 trauma hospital in ICU patients over 18 years of age receiving continuous propofol infusions for ≥3 days. Additional study inclusion criteria included vasopressor support and monitoring of serum triglycerides and creatinine. Results. Seventy-two patients, 61 males (84.7% and 11 females (15.3%, satisfied study inclusion criteria; and of these, 3 males met the study definition for PRIS, with 1 case fatality. PRIS incidence was 4.1% with a case-fatality rate of 33%. The mean duration of propofol infusion was 6.96 days. A positive linear correlation was observed between increasing triglyceride levels and infusion duration, but no correlation was observed between increasing creatinine levels and infusion duration. Conclusions. Risk factors for PRIS were confirmed as high dose infusions over prolonged periods. Increasing triglyceride levels may serve as reliable biomarkers of impending PRIS, if confirmed in future investigations with larger sample sizes.

Sympathetic responses during saline infusion into the veins of an occluded limb.

Science.gov (United States)

Cui, Jian; McQuillan, Patrick; Moradkhan, Raman; Pagana, Charles; Sinoway, Lawrence I

2009-07-15

Animal studies have shown that the increased intravenous pressure stimulates the group III and IV muscle afferent fibres, and in turn induce cardiovascular responses. However, this pathway of autonomic regulation has not been examined in humans. The aim of this study was to examine the hypothesis that infusion of saline into the venous circulation of an arterially occluded vascular bed evokes sympathetic activation in healthy individuals. Blood pressure, heart rate, and muscle sympathetic nerve activity (MSNA) responses were assessed in 19 young healthy subjects during local infusion of 40 ml saline into a forearm vein in the circulatory arrested condition. From baseline (11.8 +/- 1.2 bursts min(-1)), MSNA increased significantly during the saline infusion (22.5 +/- 2.6 bursts min(-1), P Blood pressure also increased significantly during the saline infusion. Three control trials were performed during separate visits. The results from the control trial show that the observed MSNA and blood pressure responses were not due to muscle ischaemia. The present data show that saline infusion into the venous circulation of an arterially occluded vascular bed induces sympathetic activation and an increase in blood pressure. We speculate that the infusion under such conditions stimulates the afferent endings near the vessels, and evokes the sympathetic activation.

Effect of different infusion regimens on colonic motility and efficacy of colostomy irrigation.

Science.gov (United States)

Gattuso, J M; Kamm, M A; Myers, C; Saunders, B; Roy, A

1996-10-01

The colonic motility response and short-term clinical effectiveness of colonic irrigation was studied in five patients with an end-colostomy, each of whom was studied on up to six occasions, using volumes of 500 and 1500 ml water infused under gravity and over a period of 2.5 and 5 min with a pump. The median baseline colonic luminal pressure was 14 cmH2O and rose to 42 cmH2O with a 500-ml infusion, and to 74 cmH2O with a 1500-ml infusion. Irrigation induced high-pressure (over 200 cmH2O) propagated waves which caused the efflux of colonic contents. These were more numerous after a 1500- than a 500-ml infusion (median 4.5 versus 2.0 respectively). There was no difference between the two volumes infused in the incidence of colostomy break-through before subsequent irrigation. Colostomy irrigation with 500-1500 ml water appears to produce intracolonic pressure rises that are safe. These volumes can be infused rapidly under gravity alone.

Intra-arterial and intraportal infusion liver scintigraphy using 99mTc-labeled colloid

International Nuclear Information System (INIS)

Inoue, Yusuke; Ohtake, Tohru; Momose, Toshimitsu; Watanabe, Toshiaki; Kosaka, Noboru; Nishikawa, Jun-ichi; Sasaki, Yasuhito; Sawada, Toshio; Muto, Tetsuichiro

1991-01-01

Intra-arterial infusion liver scintigraphy was performed in 11 patients with primary or metastatic liver tumor. and intraportal infusion liver scintigraphy was performed in 6 patients for prophylaxis of liver metastasis from colorectal cancer. 99m Tc-Sn colloid or 99m Tc-phytate was administered through the catheter of which tip was placed in the portal vein or the hepatic artery, and then liver image was obtained. When 99m Tc-phytate was infused intra-arterially, significant amount of the infused tracer passed through the liver and we could not get sufficient information to assess the distribution of drug administered through the catheter. On the other hand, intraportal infusion liver scintigraphy using 99m Tc-Sn colloid or 99m Tc-phytate and intra-arterial infusion liver scintigraphy using 99m Tc-Sn colloid revealed heterogenity of liver uptake, tracer uptake in spleen, low uptake area corresponding to the liver tumor and high uptake area around it. The findings will be clinically useful, and these methods are thought to be helpful to confirm the satisfactory drug distribution. (author)

Induration at Injection or Infusion Site May Reduce Bioavailability of Parenteral Phenobarbital Administration.

Science.gov (United States)

Nakayama, Hirokazu; Echizen, Hirotoshi; Ogawa, Ryuichi; Akabane, Atsuya; Kato, Toshiaki; Orii, Takao

2017-06-01

Phenobarbital is well tolerated and effective for controlling agitation or preventing convulsion at the end of life. No information is available concerning parenteral bioavailability of phenobarbital when induration develops at the injection or infusion site. We investigated whether induration at injection or infusion site is related to phenobarbital bioavailability via parenteral routes of continuous subcutaneous infusion and intermittent subcutaneous or intramuscular injection. A retrospective analysis was conducted on the medical data obtained from 18 patients who received chronic subcutaneous or intramuscular injections of phenobarbital for the prevention of convulsions and underwent plasma concentration monitoring of the drug. Patients whose concomitant medications were altered during the observation periods were excluded from the analysis. Comparisons were performed for concentration/dose (C/D) ratios obtained from patients with induration at injection or infusion sites (induration group, n = 6) and those without induration (noninduration group, n = 12). P phenobarbital may be reduced when induration develops at the injection or infusion site in patients treated parenterally by continuous subcutaneous infusion or intramuscular injection.

Analysis of pre-service and in-service views of evolution of Serbian teachers

Directory of Open Access Journals (Sweden)

Stanisavljević Jelena

2015-01-01

Full Text Available We analysed the potential differences between the conceptions of Serbian pre-service and in-service teachers using controlled parameters such as acceptance of the evolution theory. Our sample includes Primary School teachers as well as Secondary School teachers of Biology and of Language. We show that the ideas of pre-service (PreB and in-service biology teachers (InB are more evolutionary than those of their colleagues. In contrast, most creationist responses came from the groups of pre-service language (PreL and pre-service primary teachers (PreP. The agnostic teachers are more evolutionist than other teachers. The more a teacher believes in God and practices religion, the more creationist he or she is, but a great number of teachers who believe in God are evolutionist or simultaneously evolutionist and creationist. There is a positive correlation between evolutionist answers and the attitude that „Science and religion should be separated“, and „religion and politics should be separated“. [Projekat Ministarstva nauke Republike Srbije, br. 173038 i br. III 43001

Heavy metals and PAHs in canned fish supplies on the Serbian market.

Science.gov (United States)

Novakov, Nikolina J; Mihaljev, Željko A; Kartalović, Brankica D; Blagojević, Bojan J; Petrović, Jelana M; Ćirković, Miroslav A; Rogan, Dragan R

2017-09-01

The aim of this study was to determine the level of heavy metals and polycyclic aromatic hydrocarbons (PAHs) in 57 samples of canned tuna, 25 samples of canned sardines, and 16 samples of canned smoked sprouts, collected from supermarkets in Serbia. Heavy metal levels (lead, cadmium, mercury, arsenic, iron, copper, and zinc) were determined using an inductive coupled plasma mass spectrometry method. Sixteen analysed PAHs were determined using a gas chromatography-mass spectrometry method. The trace elements in canned fish were in the range (mg kg -1 ) of 0.01-0.28 for lead, 0.003-0.08 for cadmium, 0.007-0.64 for mercury, 0.17-3.73 for arsenic, 3.88-52.2 for iron, 0.2-5.95 for copper, and 1.35-44.5 for zinc. Total PAH levels reached 17.67 µg kg -1 in canned tuna and 15.12 µg kg -1 in sardines, whereas in smoked sprouts it amounted to 57.19 µg kg -1 . Some of the samples contained cadmium, arsenic, copper, and benzo(a)pyrene above the limits as set by the European and Serbian legislation.

Violence in social memory intimate beliefs regarding operation storm in the Croatian and Serbian publics

Directory of Open Access Journals (Sweden)

Đerić Gordana

2008-01-01

Full Text Available This text is part of a research conducted under the working title "What do we talk about when we are silent and what are we silent about when we are talking? - premises for the anthropology of silence about the nearest past." In the first part the author investigates the meaning of silence in the Croatian and Serbian press right before and during Croatia's Operation Storm. The ratio between silence, suppression of information and forgetting, on the one hand, and social memory, on the other, has been elaborated in the final part of the text by following reports about the anniversaries of Operation Storm in both Croatian and Serbian publics. The starting point lies in the belief that the phenomenon of silence (and suppression of information, being an immanent part of each discourse, represents an important factor in the creation of social relationships and system of value models, that it has important communication and cognitive functions and that the performance character lies in its essence. In short, silence makes it possible to form the prevailing image about this event, even if it does not construct it indirectly - through speech. The author has elaborated on the meaning of silence in the context of Operation Storm partly because studies about the breakup of Yugoslavia frequently mention silence as a manipulation strategy employed by some of the sides in the conflict (or analysts dealing with Yugoslav topics, while not a single study systematically investigates the semantic of silence and suppression of information in these conflicts. Most importantly, taking into account the frequency of direct silence in the newspaper discourse and rhetoric strategies that point at silence indirectly from the context and discourse, the author focuses on the relationship between the event (situation and silence. In order to shed light on the way in which Operation Storm is remembered, i.e. forgotten, in the stakeholders' publics and political imageries, she

intravenous infusion of chlorimipramine (anafranil)

African Journals Online (AJOL)

the already extensive outpatient facilities at Johannesburg. Hospital as well as the Tara Neuro-Psychiatric Hospital for long-term therapy. Technique of Chlorimipramine Infusion. Initially 1 ampoule of chlorimipramine 25 mg in 250 mg of 5°~ dextrose saline was administered intravenously at the rate of 60 drops per minute.

Cardiovascular effects of intravenous ghrelin infusion in healthy young men

DEFF Research Database (Denmark)

Vestergaard, Esben Thyssen; Andersen, Niels Holmark; Hansen, Troels Krarup

2007-01-01

Ghrelin infusion improves cardiac function in patients suffering from cardiac failure, and bolus administration of ghrelin increases cardiac output in healthy subjects. The cardiovascular effects of more continuous intravenous ghrelin exposure remain to be studied. We therefore studied the cardio......Ghrelin infusion improves cardiac function in patients suffering from cardiac failure, and bolus administration of ghrelin increases cardiac output in healthy subjects. The cardiovascular effects of more continuous intravenous ghrelin exposure remain to be studied. We therefore studied...... the cardiovascular effects of a constant infusion of human ghrelin at a rate of 5 pmol/kg per minute for 180 min. Fifteen healthy, young (aged 23.2 ± 0.5 yr), normal-weight (23.0 ± 0.4 kg/m2) men volunteered in a randomized double-blind, placebo-controlled crossover study. With the subjects remaining fasting, peak...... myocardial systolic velocity S′, tissue tracking TT, left ventricular ejection fraction EF, and endothelium-dependent flow-mediated vasodilatation were measured. Ghrelin infusion increased S′ 9% (P = 0.002) and TT 10% (P

Use of a variable tracer infusion method to determine glucose turnover in humans

International Nuclear Information System (INIS)

Molina, J.M.; Baron, A.D.; Edelman, S.V.; Brechtel, G.; Wallace, P.; Olefsky, J.M.

1990-01-01

The single-compartment pool fraction model, when used with the hyperinsulinemic glucose clamp technique to measure rates of glucose turnover, sometimes underestimates true rates of glucose appearance (Ra) resulting in negative values for hepatic glucose output (HGO). We focused our attention on isotope discrimination and model error as possible explanations for this underestimation. We found no difference in [3-3H] glucose specific activity in samples obtained simultaneously from the femoral artery and vein (2,400 +/- 455 vs. 2,454 +/- 522 dpm/mg) in 6 men during a hyperinsulinemic euglycemic clamp study where insulin was infused at 40 mU.m-2.min-1 for 3 h; therefore, isotope discrimination did not occur. We compared the ability of a constant (0.6 microCi/min) vs. variable tracer infusion method (tracer added to the glucose infusate) to measure non-steady-state Ra during hyperinsulinemic clamp studies. Plasma specific activity fell during the constant tracer infusion studies but did not change from base line during the variable tracer infusion studies. By maintaining a constant plasma specific activity the variable tracer infusion method eliminates uncertainty about changes in glucose pool size. This overcame modeling error and more accurately measures non-steady-state Ra (P less than 0.001 by analysis of variance vs. constant infusion method). In conclusion, underestimation of Ra determined isotopically during hyperinsulinemic clamp studies is largely due to modeling error that can be overcome by use of the variable tracer infusion method. This method allows more accurate determination of Ra and HGO under non-steady-state conditions

Targeting chemotherapy via arterial infusion for advanced gastric cancer

Directory of Open Access Journals (Sweden)

Zhi-yu CAO

2011-10-01

Full Text Available Objective To evaluate the clinical effects of chemotherapy via arterial infusion in treatment of advanced gastric cancer.Methods Forty-seven patients with advanced gastric cancer were given chemotherapy via arterial infusion.Chemotherapy plan was as follows: 5-Fluorouracil(Fu 500mg/m2,cyclophosphamide(MMX 10mg/m2,Hydroxycamptothecin(HPT 20mg/m2,once per week,2 weeks as a course,a total of 2-3 courses.Results After chemotherapy via arterial infusion,complete remission(CR was achieved in 1 case,partial remission(PR in 28 cases,stabilization of disease(SD in 16 cases,progression of disease(PD was found in 2 cases,and rate with response(CR+PR was 61.7%.Four of 28 PR patients underwent tumorectomy,the pathology revealed the presence of cancer cells around the vascular vessels,manifesting karyopyknosis,karyorrhexis,coagulation and necrosis of cytoplasm,intercellular edema,hyperplasia of fibroblasts,inflammatory cell infiltration,thickening of endothelium,and thrombosis.One,two and three-year survival rates were 70.2%,14.9% and 2.1%,respectively.The average survival period was 17.2 months.Conclusion Targeting chemotherapy via arterial infusion,as a part of the combined treatment,is beneficial to the patients with unresectable advanced gastric cancer.

Systemic, pulmonary and renal haemodynamic and renal morphologic effects of intravenously infused iodixanol

International Nuclear Information System (INIS)

Sunnegaardh, O.; Hietala, S.O.; Holtz, E.; Nycomed A/S, Oslo

1990-01-01

The systemic, pulmonary and renal haemodynamic effects following an intravenous infusion (1 ml/s, 4 ml/kg) of a non-ionic isoosmolar contrast medium (iodixanol) were investigated in 8 pigs. Histopathologic changes occurring after infusion of iodixanol were studied by repeated renal biopsies. Iodixanol caused a significant increase of cardiac output, mean right atrial pressure, mean pulmonary arterial pressure, mean pulmonary arterial occlusion pressure and mean arterial pressure. There was a decrease of the systemic and pulmonary vascular resistances. Most renal biopsies showed no pathologic findings after infusion of iodixanol but in 3 specimens proteinaceous content was observed 15 min after infusion. (orig.)

Stabilization of a percutaneously implanted port catheter system for hepatic artery chemotherapy infusion

International Nuclear Information System (INIS)

Shindoh, Noboru; Ozaki, Yutaka; Kyogoku, Shinsuke; Yamana, Daigo; Sumi, Yukiharu; Katayama, Hitoshi

1999-01-01

A port catheter system for hepatic artery infusion chemotherapy was implanted percutaneously via the left subclavian artery in 41 patients for treatment of unresectable liver metastases. The catheter tip was inserted into the gastroduodenal artery (GDA), the end hole was occluded with a guidewire fragment, and a side-hole for infusion was positioned at the bifurcation of the proper hepatic artery and the GDA. The GDA was embolized with steel coils around the infusion catheter tip via a transfemoral catheter. This procedure is designed to reduce the incidence of hepatic artery occlusion and infusion catheter dislocation.

Transarterial Infusion Chemotherapy Using Cisplatin-Lipiodol Suspension With or Without Embolization for Unresectable Hepatocellular Carcinoma

International Nuclear Information System (INIS)

Kawaoka, Tomokazu; Aikata, Hiroshi; Takaki, Shintaro; Katamura, Yoshio; Hiramatsu, Akira; Waki, Koji; Takahashi, Shoichi; Hieda, Masashi; Toyota, Naoyuki; Ito, Katsuhide; Chayama, Kazuaki

2009-01-01

We evaluate the long-term prognosis and prognostic factors in patients treated with transarterial infusion chemotherapy using cisplatin-lipiodol (CDDP/LPD) suspension with or without embolization for unresectable hepatocellular carcinoma (HCC). Study subjects were 107 patients with HCC treated with repeated transarterial infusion chemotherapy alone using CDDP/LPD (adjusted as CDDP 10mg/LPD 1ml). The median number of transarterial infusion procedures was two (range, one to nine), the mean dose of CDDP per transarterial infusion chemotherapy session was 30 mg (range, 5.0-67.5 mg), and the median total dose of transarterial infusion chemotherapy per patient was 60 mg (range, 10-390 mg). Survival rates were 86% at 1 year, 40% at 3 years, 20% at 5 years, and 16% at 7 years. For patients with >90% LPD accumulation after the first transarterial infusion chemotherapy, rates were 98% at 1 year, 60% at 3 years, and 22% at 5 years. Multivariate analysis identified >90% LPD accumulation after the first transarterial infusion chemotherapy (p = 0.001), absence of portal vein tumor thrombosis (PVTT; p < 0.001), and Child-Pugh class A (p = 0.012) as independent determinants of survival. Anaphylactic shock was observed in two patients, at the fifth transarterial infusion chemotherapy session in one and the ninth in the other. In conclusion, transarterial infusion chemotherapy with CDDP/LPD appears to be a useful treatment option for patients with unresectable HCC without PVTT and in Child-Pugh class A. LPD accumulation after the first transarterial infusion chemotherapy is an important prognostic factor. Careful consideration should be given to the possibility of anaphylactic shock upon repeat infusion with CDDP/LPD.

The European platform for financial education as incentive for the national efforts in implementing financial literacy programs: The case of the Association of Serbian Banks

Directory of Open Access Journals (Sweden)

Sredojević Slađana

2017-01-01

Full Text Available A sustainable financial system relies on two pillars: the functional and healthy financial institutions, as well as the financially competent customers-investors-entrepreneurs. The responsibility for the implementation of training programs and preparation for the well-informed choice does not lie only with the natural persons and legal entities. This is a shared responsibility of different stakeholders: individuals, families, small and medium enterprises, public administration, the Ministry of Education, the financial services sector, employers and representatives of trade unions and consumer protection organizations as well as other civil society initiatives. A prime example of such an integrated approach towards the same goal is the European Platform for Financial Education, an initiative launched by the European Banking Federation, the European Banking Training Network and other institutions (professional associations, in February 2017 in Brussels as an incentive for the national level efforts in implementing the respective financial literacy programs. In this paper we analyzed the importance and role of the European Platform for Financial Education in the case of the Serbian banking sector through the activities of the Association of Serbian Banks. These activities will be implemented by the Association of Banks of Serbia continuously throughout the year, and after the celebration of the European Money Week on 27-31 March 2017.

Differential effects of insulin injections and insulin infusions on levels ...

African Journals Online (AJOL)

Studies have shown that while injections of insulin cause an increase in fat mass, infusions of insulin increase fat mass. The aim of this paper was to test the hypothesis that if an increase in glycogen is an indicator of an impending increase in adipose mass, then insulin infusions should not increase glycogen, while insulin ...

Effect of serotonin infusions on the mean plasma concentrations of ...

African Journals Online (AJOL)

Milk samples were assayed for protein, fat and lactose constituents. The daily amounts of milk were determined throughout the experiment. Infusions of 1 ng 5HT did not change the plasma concentrations of the T3, T4 and GH throughout the experiment period. Infusions of 4 and 8 ng 5HT significantly (p<0.01) increased the ...

Simultaneous infusion of glutamine and branched-chain amino acids (BCAA) to septic rats does not have more favorable effect on protein synthesis in muscle, liver, and small intestine than separate infusions.

Science.gov (United States)

Holecek, Milan; Muthny, Tomas; Kovarik, Miroslav; Sispera, Ludek

2006-01-01

Glutamine and branched-chain amino acids (BCAA; valine, leucine, and isoleucine) are used as nutrition supplements in the treatment of proteocatabolic illness. We hypothesized that simultaneous administration of BCAA and glutamine affects protein metabolism more significantly than separate administration. In the present study, we evaluated their effect on protein synthesis in skeletal muscle, liver, and jejunum of septic rats. Twenty-four hours after induction of sepsis by subcutaneous injection of turpentine, the rats were infused for 6 hours with 5 mL of 1.75% glutamine, 1.75% BCAA, 1.75% glutamine+BCAA, or saline solution. The control group consisted of intact rats infused with saline. Protein synthesis was measured at the end of infusion by a "flooding method" with [3,4,5-(3)H]phenylalanine. In turpentine-treated animals, we observed a decrease in glutamine concentration in blood plasma and skeletal muscle, a decrease in BCAA concentration in liver and jejunum, and a decrease in protein synthesis in all tissues. Glutamine or glutamine+BCAA infusion increased glutamine concentration in plasma and muscle and stimulated protein synthesis in the liver. The BCAA infusion enhanced concentrations of BCAA in plasma and tissues, but the effect of BCAA on protein synthesis was insignificant. Synergistic effect of simultaneous infusion of glutamine and BCAA on protein synthesis was not observed. We conclude that glutamine infusion to rats with septic injury may significantly improve impaired protein synthesis in the liver and that there is no synergistic effect of glutamine and BCAA infusion on protein synthesis in skeletal muscle, liver, and jejunum.

Tracer measured substrate turnover requires arterial sampling downstream of infusion site

International Nuclear Information System (INIS)

Stanley, W.C.; Neese, R.A.; Gertz, E.W.; Wisneski, J.A.; Morris, D.L.; Brooks, G.A.

1986-01-01

Measurement of metabolite turnover (Rt) with radioactive tracers is done by either infusing tracer venously and sampling specific activity (SA) arterially (V-A modes), or by infusing into the aorta and sampling venous blood (A-V mode). Using the Fick principle, the necessity for using the V-A mode can be demonstrated. If tracer is infused into the left ventricle, in a steady state the Rt is the product of arterial trace concentration, the cardiac output, and the tracer extraction ratio for the whole body. This is expressed as: Rt = Ca x Qx ((*Ca - *Cv)/*Ca) (Eq1) where C=trace concentration (μmol/ml), *C=tracer conc. (dpm/ml), a=arterial, v-=mixed venous, and Q=cardiac output (ml/min). Rearranging the equation: Rt = Qx(*Ca - *Cv)/SAa = F/SAa (Eq2) where SAa is *Ca/Ca, and Qx (*Ca-*Cv) equals the infusion rate (F). The authors compared Eqs1 and 2 (Rt = F/SAa) in 3 anesthetized dogs in which [1- 14 C] lactate was infused into the left ventricle, and blood was sampled arterially downstream from the infusion site and in the pulmonary artery. Eqs 1 and 2 gave similar results for Rt (45.9 vs. 43.9 μmol/kg min), while substituting SAv for SAa (A-V mode) into Eq 2 gave a higher Rt (53.6). When SAv (A-V mode) is used, the specific activity seen by the tissues (SAa) is not considered in the calculation of Rt. Therefore, only the V-A mode meets the requirements for tracer measured metabolite turnover

Resin infusion of large composite structures modeling and manufacturing process

Energy Technology Data Exchange (ETDEWEB)

Loos, A.C. [Michigan State Univ., Dept. of Mechanical Engineering, East Lansing, MI (United States)

2006-07-01

The resin infusion processes resin transfer molding (RTM), resin film infusion (RFI) and vacuum assisted resin transfer molding (VARTM) are cost effective techniques for the fabrication of complex shaped composite structures. The dry fibrous preform is placed in the mold, consolidated, resin impregnated and cured in a single step process. The fibrous performs are often constructed near net shape using highly automated textile processes such as knitting, weaving and braiding. In this paper, the infusion processes RTM, RFI and VARTM are discussed along with the advantages of each technique compared with traditional composite fabrication methods such as prepreg tape lay up and autoclave cure. The large number of processing variables and the complex material behavior during infiltration and cure make experimental optimization of the infusion processes costly and inefficient. Numerical models have been developed which can be used to simulate the resin infusion processes. The model formulation and solution procedures for the VARTM process are presented. A VARTM process simulation of a carbon fiber preform was presented to demonstrate the type of information that can be generated by the model and to compare the model predictions with experimental measurements. Overall, the predicted flow front positions, resin pressures and preform thicknesses agree well with the measured values. The results of the simulation show the potential cost and performance benefits that can be realized by using a simulation model as part of the development process. (au)

Experience of the air medical evacuation team of Serbian armed forces in the united nations mission in the Democratic Republic of Congo - deployment stress and psychological adaptation

Directory of Open Access Journals (Sweden)

Joković Danilo B.

2016-01-01

Full Text Available Background/Aim. Wars of the nineties in former Yugoslavia, Somalia, Rwanda imposed new tasks to the United Nations (UN forces, such as providing humanitarian aid, protection of civilians, peacekeeping, and in many instances providing armed enforcement of peace. The aim of this study was an observational analysis of Serbian participation in the UNs Mission in the Democratic Republic of Congo with the emphasis on stress and coping techniques. Methods. Serbian contribution in this mission dates back to April 2003 till the present days with a military contingent consisting of six members as a part of Air Medical Evacuation Team. The observed stressogenous factors acted before arrival to the mission area and in the mission area. In this paper we analysed ways to overcome them. Results. The productive ways of overwhelming stress used in this mission were: honesty and openness in interpersonal communications, dedication to work, maintaining discipline and order, strict following of appropriate regime of work, diet, rest and recreation; regular communication with family and organizing and participation in various social, cultural and sports manifestations. Conclusion. This analysis indicates that out of all the observed factors, the most important is appropriate selection of personnel.

Palliation of inoperable head and neck cancer: combined intra-arterial infusion chemotherapy and irradiation

International Nuclear Information System (INIS)

Armstrong, A.L.; Meeker, W.R.

1978-01-01

Palliation of unresectable head and neck cancer remains a difficult problem. Because of excellent results reported by others with infusion of vinblastine, methotrexate, and 5-fluorouracil into the external carotid artery followed by irradiation before curative surgery, we applied this technic to 22 patients with advanced head and neck cancer. Fifteen patients from this group who had chemotherapy infusion followed by radiation therapy are compared with 21 patients who received radiation therapy alone. Both groups were similar in distribution of primary site, histology, and TNM stage. Of 15 patients, 14 (93%) had partial or complete tumor regression after both arterial chemotherapy infusion and irradiation, while 14 of 17 patients (82%) receiving primary irradiation had partial or complete response. Drug toxicity and complications related to infusion occurred in all patients. Most patients in both groups had short survivals (mean of 14.1 months in infusion chemotherapy and radiation vs 9.1 months in primary irradiation). One patient remains alive in the infusion group and two in the control group; however, all have recurrent disease. Results indicate a slight increase in survival time with the addition of infusion chemotherapy to irradiation in palliative treatment of head and neck cancer

Chemoradiotherapy using retrograde superselective intra-arterial infusion for advanced oral cancer

International Nuclear Information System (INIS)

Mitsudo, Kenji; Iwai, Toshinori; Mitsunaga, Sachiyo

2011-01-01

Concurrent chemoradiotherapy using retrograde superselective intra-arterial infusion demonstrates good local control and overall survival rates due to the advantage of simultaneous infusion of anticancer agent with the synergistic effects of chemotherapy and radiotherapy. This study evaluated the therapeutic results, overall survival and local control rates in patients with advanced oral cancer treated with definitive concurrent chemoradiotherapy using retrograde superselective intra-arterial infusion. A total of 688 patients with carcinoma of the head and neck were referred to our institution between January 2001 and December 2006. Among them, 175 patients with carcinoma of the oral cavity underwent definitive concurrent chemoradiotherapy using retrograde superselective intra-arterial infusion. Treatment consisted of superselective intra-arterial infusions (docetaxel, total 60 mg/m 2 , cisplatin, total 125-150 mg/m 2 ) and daily concurrent radiotherapy (total 50-60 Gy) for 5-6 weeks. Four weeks after the completion of all treatments, patients underwent biopsy of the primary lesion and radiological examinations. Complete response (CR) of the primary site was achieved in 160 (91.4%) of the 175 patients. Residual disease at the primary site was seen in 15 patients (8.6%), and 14 patients (8.0%) showed local recurrence during follow-up. Five-year survival and local control rates were 71.6% and 82.2%, respectively. (author)

Insulin compatibility with polymer materials used in external pump infusion systems.

Science.gov (United States)

Melberg, S G; Havelund, S; Villumsen, J; Brange, J

1988-04-01

In a study designed to mimic actual user conditions for external insulin pump infusion, the insulin quality after passage through the infusion set was assessed by various analytical methods, including high performance liquid chromatography. The two infusion sets tested consisted of, firstly, a polyvinylchloride/rubber syringe and a polyvinylchloride catheter sterilized by gamma irradiation and, secondly, a polyethylene/polypropylene syringe connected to a polyethylene catheter and sterilized by ethylene oxide. The insulin solution delivered through the PVC infusion set showed a reduction of preservative to less than 30% of the initial content and increased formation of chemical transformation products of insulin varying from twice the reference level during the first day to more than three times on the third day. By contrast, the polyethylene/polypropylene infusion system showed only a minor decrease in preservative content and no increase in chemical transformation. These effects were observed irrespective of the brand of insulin and were not affected by increase of the zinc content of the insulin solution. Investigation of the influence of the sterilization methods performed on polyvinylchloride and polyethylene catheters revealed that gamma irradiated polyvinylchloride catheters were markedly harmful to the insulin solution, whereas ethylene oxide sterilization did not influence the chemical stability of insulin.

Anomalies in target-controlled infusion: an analysis after 20 years of clinical use.

Science.gov (United States)

Engbers, F H M; Dahan, A

2018-05-01

Although target-controlled infusion has been in use for more than two decades, its benefits are being obscured by anomalies in clinical practice caused by a number of important problems. These include: a variety of pharmacokinetic models available in open target-controlled infusion systems, which often confuse the user; the extrapolation of anthropomorphic data which provokes anomalous adjustments of dosing by such systems; and the uncertainty of regulatory requirements for the application of target-controlled infusion which causes uncontrolled exploitation of drugs and pharmacokinetic models in target-controlled infusion devices. Comparison of performance of pharmacokinetic models is complex and mostly inconclusive. However, a specific behaviour of a model in a target-controlled infusion system that is neither intended nor supported by scientific data can be considered an artefact or anomaly. Several of these anomalies can be identified in the current commercially available target-controlled infusion systems and are discussed in this review. © 2018 The Association of Anaesthetists of Great Britain and Ireland.

Home therapy with continuous infusion of factor VIII after minor surgery or serious haemorrhage.

Science.gov (United States)

Varon, D; Schulman, S; Bashari, D; Martinowitz, U

1996-10-01

Administration of factor VIII (F VIII) concentrates by continuous infusion is now routinely used at several haemophilia centers but almost exclusively for hospitalized patients. We evaluated various aspects of home therapy with continuous infusion of an immunoaffinity purified F VIII concentrate (Monoclate P®, Armour) in patients who would normally have been treated with high doses in bolus injections or with continuous infusion as in-patients. Twenty haemophilia A patients, eight after minor surgery and 12 for serious haemorrhage, received continuous infusion with undiluted F VIII by a minipump for a mean of 0.9 days in the hospital, followed by 3.3 days at home. Infusion bags were exchanged every 2.5 days. No haemorrhagic complications occurred, and five haemorrhages that had been resistant to treatment with bolus injections responded promptly to the continuous infusion. There were no technical problems and patient compliance and acceptance was good. We find this mode of therapy safe, efficacious and convenient for the patients as well as for the staff.

Cardiovascular effects of dobutamine and phenylephrine infusion in sevoflurane-anesthetized Thoroughbred horses.

Science.gov (United States)

Ohta, Minoru; Kurimoto, Shinjiro; Ishikawa, Yuhiro; Tokushige, Hirotaka; Mae, Naomi; Nagata, Shun-ichi; Mamada, Masayuki

2013-11-01

To determine dose-dependent cardiovascular effects of dobutamine and phenylephrine during anesthesia in horses, increasing doses of dobutamine and phenylephrine were infused to 6 healthy Thoroughbred horses. Anesthesia was induced with xylazine, guaifenesin and thiopental and maintained with sevoflurane at 2.8% of end-tidal concentration in all horses. The horses were positioned in right lateral recumbency and infused 3 increasing doses of dobutamine (0.5, 1.0 and 2.0 µg/kg/min) for 15 min each dose. Following to 30 min of reversal period, 3 increasing doses of phenylephrine (0.25, 0.5 and 1.0 µg/kg/min) were infused. Cardiovascular parameters were measured before and at the end of each 15-min infusion period for each drug. Blood samples were collected every 5 min during phenylephrine infusion period. There were no significant changes in heart rate throughout the infusion period. Both dobutamine and phenylephrine reversed sevoflurane-induced hypotension. Dobutamine increased both mean arterial blood pressure (MAP) and cardiac output (CO) as the result of the increase in stroke volume, whereas phenylephrine increased MAP but decreased CO as the result of the increase in systemic vascular resistance. Plasma phenylephrine concentration increased dose-dependently, and these values at 15, 30 and 45 min were 6.2 ± 1.2, 17.0 ± 4.8 and 37.9 ± 7.3 ng/ml, respectively.

Reduction of {sup 68}Ga-PSMA renal uptake with mannitol infusion. Preliminary results

Energy Technology Data Exchange (ETDEWEB)

Matteucci, Federica; Caroli, Paola; Celli, Monica; Fantini, Lorenzo; Paganelli, Giovanni [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Nuclear Medicine Unit, Meldola (Italy); Mezzenga, Emilio; Sarnelli, Anna [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Medical Physics Unit, Meldola (Italy); Di Iorio, Valentina [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Oncology Pharmacy, Meldola (Italy); Moretti, Andrea; Galassi, Riccardo [AUSL Romagna, Nuclear Medicine Unit, Forli (Italy); De Giorgi, Ugo [Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Department of Medical Oncology, Meldola (Italy)

2017-12-15

Urea-based prostate-specific membrane antigen (PSMA) ligands labelled with {sup 68}Ga or {sup 177}Lu are new tracers with great potential for theranostic approaches in prostate cancer. However, clinical studies have shown that the kidneys are one of the off-target organs along with the salivary and lacrimal glands. In the kidneys, PSMA is physiologically expressed in the apical epithelium of the proximal tubules, and mannitol acts as an osmotic diuretic in these tubules. We investigated the potential of mannitol to reduce renal uptake of {sup 68}Ga-PSMA. Kidney uptake (SUVmax) was calculated in nine patients undergoing {sup 68}Ga-PSMA PET/CT at baseline (b-PET/CT) and after intravenous infusion of 500 ml of 10% mannitol (m-PET/CT). Two different infusion schemes for mannitol were used: (1) 500 ml mannitol was infused over 40 min after {sup 68}Ga-PSMA administration (A-infusion) and (2) 250 ml mannitol was infused over 15 min before and again after {sup 68}Ga-PSMA administration (B-infusion). In patients receiving the A-infusion, mean SUV{sub max} increased by 11.9% and 7.4% in the right and left kidney, respectively. In patients receiving the B-infusion, mean SUV{sub max} decreased by 24.3% and 22.4% in the right and left kidney, respectively. Our preliminary findings indicate that mannitol may play a role in reducing off-target {sup 68}Ga-PSMA renal uptake. Administration of the osmotic diuretic should be rapid and start before {sup 68}Ga-PSMA injection. These results warrant dosimetric studies in patients treated with {sup 177}Lu-PSMA to find the best scheme for mannitol administration. (orig.)

Adjectives meaning ‘curly’ in the Serbian language: On the material of the common Slavic linguistic atlas

Directory of Open Access Journals (Sweden)

Bjeletić Marta Ž.

2016-01-01

Full Text Available This paper draws on etymological analysis of Serbian adjectives meaning ‘curly’, registered in the material of the Common Slavic Linguistic Atlas (the Personal Characteristics of Man volume. Those that can be traced back to Pro to-Slavic prototypes (kokorav, kudrav, kuštrav have no clear and/or in disputable etymology. The same is true of the adjectives of uncertain Pro to-Slavic antiquity (čečerav, grguljav. The se forms are evidently expressive, which is indicated by their variants (čečurav, čičurav; gregurav, grgurav, and the expressive lexicon is a language domain where no single etymological solution is absolutely reliable. Some of the adjectives analysed result from formal and semantic contaminations, which obscures their original structures (čečverast, čkogrtljav, kekerast, kovrdžav, kvrčav. The most transparent among them are deverbals (čupav, frckan, grčkav, vrtkav, although not all of the respective verbs have generally accepted interpretations at the Proto-Slavic level. The concepts lying at the basis of motivation models, realised by adjectives meaning ‘curly’, include the following: ‘to tear, pull apart’ (čupav, kudrav, ‘to bend’ (kuštrav, ‘something bent, knotty’ (grguljav, ‘to turn, shake’ (frckav, kovrčav, vrtkav, ‘to contract’ (grčkav, kvrčav, ‘something raised, sticking out’ (čečerav, čečverast, kekerast, kokorav. However, the final conclusions about the antiquity and distribution of the particular lexemes, onomasiological tendencies and potential lexical isoglosses can be reached only through an analysis of the complete Slavic material, which will be available after the publication of the mentioned volume of the CSLA. [Project of the Serbian Ministry of Education, Science and Technological Development, Grant no. 178007: Etimološka istraživanja srpskog jezika i izrada Etimološkog rečnika srpskog jezika

Apparent contact angle and contact angle hysteresis on liquid infused surfaces.

Science.gov (United States)

Semprebon, Ciro; McHale, Glen; Kusumaatmaja, Halim

2016-12-21

We theoretically investigate the apparent contact angle and contact angle hysteresis of a droplet placed on a liquid infused surface. We show that the apparent contact angle is not uniquely defined by material parameters, but also has a dependence on the relative size between the droplet and its surrounding wetting ridge formed by the infusing liquid. We derive a closed form expression for the contact angle in the limit of vanishing wetting ridge, and compute the correction for small but finite ridge, which corresponds to an effective line tension term. We also predict contact angle hysteresis on liquid infused surfaces generated by the pinning of the contact lines by the surface corrugations. Our analytical expressions for both the apparent contact angle and contact angle hysteresis can be interpreted as 'weighted sums' between the contact angles of the infusing liquid relative to the droplet and surrounding gas phases, where the weighting coefficients are given by ratios of the fluid surface tensions.

Effects of erythrocyte infusion on VO2max at high altitude

DEFF Research Database (Denmark)

Young, Jette Feveile; Sawka, M N; Muza, S R

1996-01-01

This study investigated whether autologous erythrocyte infusion would ameliorate the decrement in maximal O2 uptake (VO2max) experienced by lowlanders when they ascend to high altitude. VO2max was measured in 16 men (treadmill running) at sea level (SL) and on the 1st (HA1) and 9th (HA9) days...... of high-altitude (4,300 m) residence. After VO2max was measured at SL, subjects were divided into two matched groups (n = 8). Twenty-four hours before ascent to high altitude, the experimental group received a 700-ml infusion of autologous erythrocytes and saline (42% hematocrit), whereas the control...... group received only saline. The VO2max of erythrocyte-infused [54 +/- 1 (SE) ml.kg-1.min-1] and control subjects (52 +/- 2 ml.kg-1.min-1) did not differ at SL before infusion. The decrement in VO2max on HA1 did not differ between groups, averaging 26% overall, despite higher (P

Decreasing the infusion rate reduces the proarrhythmic risk of NS-7

DEFF Research Database (Denmark)

Detre, Elke; Thomsen, Morten Bækgaard; Beekman, Jet D

2005-01-01

1 The rate of infusion has been suggested to be important for drug-induced torsades de pointes (TdP) arrhythmias. We investigated the repolarisation-prolonging effects and proarrhythmic properties of NS-7, a neuroprotective drug in development, using two different infusion rates. 2 A fast (5 min...... intravenously (i.v.)) escalating dosing regimen (0.3 and 3.0 mg kg(-1), n=4) of NS-7 was investigated in anaesthetised control dogs in sinus rhythm (SR). This was compared to a slow infusion (60 min i.v.) of one dose (3.0 mg kg(-1), n=4) NS-7. The similar dosing regimens were investigated in anaesthetised dogs...... with chronic, complete AV block (CAVB), an animal model of TdP (n=6). 3 No electrophysiological effects were seen after 0.3 mg kg(-1) NS-7. Fast infusion of 3.0 mg kg(-1) caused prolongation of repolarisation, for example, heart rate corrected QT interval (QT(c)): in SR: 6+/-1%; in CAVB: 10+/-7%, which...

Existence of a current price as a precondition for abstract method for calculating damages in international and Serbian sales law

Directory of Open Access Journals (Sweden)

Fišer-Šobot Sandra

2014-01-01

Full Text Available If the contract is avoided and there is a current price for the goods, the party claiming damages may recover the difference between the price fixed by the contract and the current price at specific time and at specific place. Abstract calculation of loss is possible only when the contract goods have current price. Current price is the price generally charged for such goods sold under comparable circumstances in the trade concerned. According to the CISG and Serbian Law of Obligations, for the determination of the current price is relevant time of avoidance. This general rule is not applicable in international sales law when the party claiming damages has avoided the contract after taking over the goods. In that case, the current price at the time of taking over shall be applicable instead of the current price at the time of avoidance. Current price rule contained in the Art. 76(2 of the CISG presupposes that the current price is the price prevailing at the place where the delivery of the goods should have been made, or if there is no current price at the place, the price at such other place as serves as a reasonable substitute, making due allowance for differences in the cost of transporting the goods. Pursuant to Art. 524(2 Of Serbian Law of Obligations, however, relevant is the price in the market of the place of effecting the transaction. Formulation place of effecting the transaction is unclear and vague and can create different problems. Therefore, this rule should be amended and the relevant place should be the place of delivery.

The development of the penal system in Serbian criminal law

Directory of Open Access Journals (Sweden)

Jakšić Dušan

2013-01-01

Full Text Available The continuous development of the penal system in Serbia is reflected in significant changes within the criminal legislative solutions. The most important legal document of the medieval Serbia, 'Dušan's Code' was characterized by harsh corporal and death punishments taken from the Byzantine law. During the Ottoman period 'Dušan's Code' was no longer in use, and with the beginning of the First Serbian Uprising, the adoption of individual legislations began. The Criminal Code of the Principality of Serbia, adopted in 1860, introduced a novelty of major and minor penalties, including, most importantly, several types of detention. The Criminal Code of the Kingdom of Yugoslavia was adopted in 1929 and it predicted different types of sanctions other than fines. The main feature of the Criminal Code of the Kingdom of Yugoslavia was permanent abolition of the corporal punishment. After the Second World War, the newly formed government adopted new criminal codes and new forms of punishment, which remained unchanged from the Novel in 1959 up until the dissolution of the SFRY. Contemporary criminal legislation of the Republic of Serbia is characterized by the abolition of the death penalty, seizure of property and the introduction of new penalties, which should, instead of short prison sentences, serve as an alternative. Throughout its statehood, from the Middle Ages up until today, Serbia has always had a continuity of the penal system development parallel with its development, primarily in Europe.

A randomised controlled trial of two infusion rates to decrease reactions to antivenom.

Directory of Open Access Journals (Sweden)

Geoffrey K Isbister

Full Text Available BACKGROUND: Snake envenoming is a major clinical problem in Sri Lanka, with an estimated 40,000 bites annually. Antivenom is only available from India and there is a high rate of systemic hypersensitivity reactions. This study aimed to investigate whether the rate of infusion of antivenom reduced the frequency of severe systemic hypersensitivity reactions. METHODS AND FINDINGS: This was a randomized comparison trial of two infusion rates of antivenom for treatment of non-pregnant adult patients (>14 y with snake envenoming in Sri Lanka. Snake identification was by patient or hospital examination of dead snakes when available and confirmed by enzyme-immunoassay for Russell's viper envenoming. Patients were blindly allocated in a 11 randomisation schedule to receive antivenom either as a 20 minute infusion (rapid or a two hour infusion (slow. The primary outcome was the proportion with severe systemic hypersensitivity reactions (grade 3 by Brown grading system within 4 hours of commencement of antivenom. Secondary outcomes included the proportion with mild/moderate hypersensitivity reactions and repeat antivenom doses. Of 1004 patients with suspected snakebites, 247 patients received antivenom. 49 patients were excluded or not recruited leaving 104 patients allocated to the rapid antivenom infusion and 94 to the slow antivenom infusion. The median actual duration of antivenom infusion in the rapid group was 20 min (Interquartile range[IQR]:20-25 min versus 120 min (IQR:75-120 min in the slow group. There was no difference in severe systemic hypersensitivity reactions between those given rapid and slow infusions (32% vs. 35%; difference 3%; 95%CI:-10% to +17%;p = 0.65. The frequency of mild/moderate reactions was also similar. Similar numbers of patients in each arm received further doses of antivenom (30/104 vs. 23/94. CONCLUSIONS: A slower infusion rate would not reduce the rate of severe systemic hypersensitivity reactions from current high

Distribution of 14C-morphine and macromolecules in the brain and liver and their nuclei in pregnant rats and their foetuses after infusion of morphine into pregnant rats at near-term

International Nuclear Information System (INIS)

Steele, W.J.; Johannesson, T.

1975-01-01

Timed-pregnant (day 21 or 22) Sprague-Dawley rats were administered 14 C-morphine (2.85 mci/mmol) 5 mg/kg/hr, or saline in equivalent volumes, by continuous intravenous infusion for periods of up to 4hrs. The brains and livers of the maternal rats and of their foetuses were collected and their nuclei were isolated. The tissues and nuclei isolated from them were analyzed for DNA, RNA, protein content and radioactivity. Morphine infused maternal rats exhibited no significant difference in the total amount of DNA, RNA and protein in the brain or in the concentration of these constituents in brain nuclei. The concentration of nuclear RNA in foetal brain of morphine infused mothers was significantly lower at 4 hrs than that of saline infused controls. It was concluded that RNA synthesis in the foetal brain must be much more sensitive to the inhibitory effect of morphine on macromolecular synthesis than that in maternal brain. The change in nuclear RNA concentration in foetal brain became significantly different when morphine reached its highest level in foetal brain nuclei. The morphine concentration (pmol 14 C-morphine equivalents per mg DNA) in the brain of foetal and maternal rats was the same at each time period, whereas the maternal liver levels were at least eight times greater than those in foetal liver. The concentrations in foetal brain nuclei were 2-14 times greater than those in maternal brain nuclei, whereas levels in the latter were found to be low and virtually constant at all time periods tested. It was concluded that foetal brain nuclei have a greater capacity to bind or retain morphine than maternal brain nuclei. (author)

Haemolysis following rapid experimental red blood cell transfusion--an evaluation of two infusion pumps

DEFF Research Database (Denmark)

Hansen, Tom Giedsing; Sprogøe-Jakobsen, U; Pedersen, C M

1998-01-01

The vast majority of infusion pumps used for rapid transfusion of large amounts of blood have never been properly examined regarding their influence on the quality of the red blood cells (RBCs) infused. In this study, we evaluated the effect of two different infusion pumps on the degree of RBC...

Use of di(2-ethylhexyl)phthalate-containing infusion systems increases the risk for cholestasis.

Science.gov (United States)

von Rettberg, Heike; Hannman, Torsten; Subotic, Ulrike; Brade, Joachim; Schaible, Thomas; Waag, Karl Ludwig; Loff, Steffan

2009-08-01

Most polyvinylchloride infusion systems are plasticized with up to 60% of di(2-ethylhexyl)phthalate (DEHP). DEHP is easily extracted from the tubing by total parenteral nutrition (TPN) solutions and has been shown to have toxic effects on various organ systems including the liver in animals and humans. A role was postulated for DEHP in the development of hepatobiliary dysfunction in premature and newborn infants receiving parenteral nutrition, and the incidence of cholestasis was investigated after changing from polyvinylchloride infusion systems to polyvinylchloride-free infusion systems. Two 3-year periods from 1998 to 2004 were investigated retrospectively before and after changing from polyvinylchloride to polyvinylchloride-free infusion systems in our department. This resulted in 1 group of 30 patients treated with polyvinylchloride lines and a second group of 46 patients treated with polyvinylchloride-free lines. The 2 groups were examined for the incidence of cholestasis and other possible contributing factors. Statistics were performed by using SAS software (SAS Institute, Cary, NC). After changing infusion systems, the incidence of cholestasis dropped from 50% to 13%. Using DEHP-plasticized polyvinylchloride infusion systems for TPN increased the risk for cholestasis by a factor of 5.6. The use of polyvinylchloride lines correlated strongly with the development of TPN-associated cholestasis (P = .0004). Using DEHP-containing polyvinylchloride infusions systems contributes to the development of cholestasis. Therefore, the use of DEHP-free infusion systems for TPN is recommended, especially in premature and newborn infants.

Complications Following Balloon-Occluded Arterial Infusion Chemotherapy for Pelvic Malignancies

International Nuclear Information System (INIS)

Sugimoto, Koji; Hirota, Shozo; Imanaka, Kazufumi; Kawabe, Tetsuya; Nakayama, Yoshiharu; Takeuchi, Yasuhito

1999-01-01

Purpose: To evaluate the incidence and causes of complications associated with balloon-occluded arterial infusion chemotherapy (BOAI) for pelvic malignancies. Methods: In 34 courses of BOAI in 22 patients with pelvic malignancies, we analyzed the incidence of complications as well as the effect of the dose of the anticancer drugs, the infusion site, and the number of BOAI administrations on these complications. Complications were divided into two categories: cystitis-like symptoms and neurological complications such as pain, numbness, and paresthesia of the lower extremities and the hip. Results: Eleven patients (50%) suffered from complications, seven (31.8%) from neurological complications and four (18.2%) from cystitis-like symptoms. The complications appeared in 14 courses (42.4%) of BOAI, neurological complications in 10 (30.3%) and cystitis-like symptoms in four (12.1%). A high dose of anti-cancer drugs and infusion from the anterior division tended to induce neurological complications more frequently; however, the cystitis-like symptoms were not related to any factors. Conclusion: Our results indicate that a smaller dose of anti-cancer drugs should be infused from the bilateral internal iliac arteries for safer pelvic BOAI

Residues and contaminants in tea and tea infusions: a review.

Science.gov (United States)

Abd El-Aty, A M; Choi, Jeong-Heui; Rahman, Md Musfiqur; Kim, Sung-Woo; Tosun, Alev; Shim, Jae-Han

2014-01-01

Consumers are very aware of contaminants that could pose potential health hazards. Most people drink tea as an infusion (adding hot water); however, in some countries, including India, China and Egypt, tea is drunk as a decoction (tea and water are boiled together). An infusion usually brings the soluble ingredients into solution, whereas a decoction brings all soluble and non-soluble constituents together. Therefore, a cup of tea may contain various kinds of contaminants. This review focuses on green and black tea because they are most commonly consumed. The target was to examine the transfer rate of contaminants - pesticides, environmental pollutants, mycotoxins, microorganisms, toxic heavy metals, radioactive isotopes (radionuclides) and plant growth regulators - from tea to infusion/brewing, factors contributing to the transfer potential and contaminants degradation, and residues in or on the spent leaves. It is concluded that most contaminants leaching into tea infusion are not detected or are detected at a level lower than the regulatory limits. However, the traditional practice of over-boiling tea leaves should be discouraged as there may be a chance for more transfer of contaminants from the tea to the brew.

Association between continuous peripheral i.v. infusion of 3% sodium chloride injection and phlebitis in adults.

Science.gov (United States)

Meng, Lina; Nguyen, Cherwyn M; Patel, Samit; Mlynash, Michael; Caulfield, Anna Finley

2018-03-01

One institution's experience with use of peripheral i.v. (PIV) catheters for prolonged infusions of 3% sodium chloride injection at rates up to 100 mL/hr is described. A prospective, observational, 13-month quality assurance project was conducted at an academic medical center to evaluate frequencies of patient and catheter phlebitis among adult inpatients who received both an infusion of 3% sodium chloride injection for a period of ≥4 hours through a dedicated PIV catheter and infusions of routine-care solutions (RCSs) through separate PIV catheters during the same hospital stay. Sixty patients received PIV infusions through a total of 291 catheters during the study period. The majority of patients (78%) received infusions of 3% sodium chloride injection for intracranial hypertension, with 30% receiving such infusions in the intensive care unit. Phlebitis occurred in 28 patients (47%) during infusions of 3% sodium chloride and 26 patients (43%) during RCS infusions ( p = 0.19). Catheter phlebitis occurred in 73 catheters (25%), with no significant difference in the frequencies of catheter phlebitis with infusion of 3% sodium chloride versus RCSs (30% [32 of 106 catheters]) versus 22% [41 of 185 catheters]), p = 0.16). Patient and catheter phlebitis rates were not significantly different with infusions of 3% sodium chloride injection versus RCSs, suggesting that an osmolarity cutoff value of 900 mOsm/L for peripheral infusions of hypertonic saline solutions may not be warranted. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.