WorldWideScience

Sample records for induction bunching module

  1. Bunch identification module

    International Nuclear Information System (INIS)

    Fox, J.D.

    1981-01-01

    This module provides bunch identification and timing signals for the PEP Interaction areas. Timing information is referenced to the PEP master oscillator, and adjusted in phase as a function of region. Identification signals are generated in a manner that allows observers in all interaction regions to agree on an unambiguous bunch identity. The module provides bunch identification signals via NIM level logic, upon CAMAC command, and through LED indicators. A front panel ''region select'' switch allows the same module to be used in all regions. The module has two modes of operation: a bunch identification mode and a calibration mode. In the identification mode, signals indicate which of the three bunches of electrons and positrons are interacting, and timing information about beam crossing is provided. The calibration mode is provided to assist experimenters making time of flight measurements. In the calibration mode, three distinct gating signals are referenced to a selected bunch, allowing three timing systems to be calibrated against a common standard. Physically, the bunch identifier is constructed as a single width CAMAC module. 2 figs., 1 tab

  2. Evolution of dense spatially modulated electron bunches

    Science.gov (United States)

    Balal, N.; Bratman, V. L.; Friedman, A.

    2018-03-01

    An analytical theory describing the dynamics of relativistic moving 1D electron pulses (layers) with the density modulation affected by a space charge has been revised and generalized for its application to the formation of dense picosecond bunches from linear accelerators with laser-driven photo injectors, and its good agreement with General Particle Tracer simulations has been demonstrated. Evolution of quasi-one-dimensional bunches (disks), for which the derived formulas predict longitudinal expansion, is compared with that for thin and long electron cylinders (threads), for which the excitation of non-linear waves with density spikes was found earlier by Musumeci et al. [Phys. Rev. Lett. 106(18), 184801 (2011)] and Musumeci et al. [Phys. Rev. Spec. Top. -Accel. Beams 16(10), 100701 (2013)]. Both types of bunches can be used for efficiency enhancement of THz sources based on the Doppler frequency up-shifted coherent spontaneous radiation of electrons. Despite the strong Coulomb repulsion, the periodicity of a preliminary modulation in dense 1D layers persists during their expansion in the most interesting case of a relatively small change in particle energy. However, the period of modulation increases and its amplitude decreases in time. In the case of a large change in electron energy, the uniformity of periodicity is broken due to different relativistic changes in longitudinal scales along the bunch: the "period" of modulation decreases and its amplitude increases from the rear to the front boundary. Nevertheless, the use of relatively long electron bunches with a proper preliminary spatial modulation of density can provide a significantly higher power and a narrower spectrum of coherent spontaneous radiation of dense bunches than in the case of initially short single bunches with the same charge.

  3. Use beam steering dipoles to minimize aberrations associated with off-centered transit through the induction bunching module. Design an improved NDCX-I drift compression section to make best use of the new bunching module to optimize planned initial NDCX-I target experiments

    International Nuclear Information System (INIS)

    HIFS-VNL; Seidl, Peter; Seidl, P.; Barnard, J.; Bieniosek, F.; Coleman, J.; Grote, D.; Leitner, M.; Gilson, E.; Logan, B.G.; Lund, S.; Lidia, S.; Ni, P.; Ogata, D.; Roy, P.; Waldron, W.; Welch, D.; Wooton, C.

    2008-01-01

    This milestone has been met by: (1) calculating steering solutions and implementing them in the experiment using the three pairs of crossed magnetic dipoles installed in between the matching solenoids, S1-S4. We have demonstrated the ability to center the beam position and angle to < 1 mm and < 1 mrad upstream of the induction bunching module (IBM) gap, compared to uncorrected beam offsets of several millimeters and milli-radians. (2) Based on LSP and analytic study, the new IBM, which has twice the volt-seconds of our first IBM, should be accompanied by a longer drift compression section in order to achieve a predicted doubling of the energy deposition on future warm-dense matter targets. This will be accomplished by constructing a longer ferro-electric plasma source. (3) Because the bunched current is a function of the longitudinal phase space and emittance of the beam entering the IBM we have characterized the longitudinal phase space with a high-resolution energy analyzer

  4. Induction Acceleration of a Single RF Bunch in the KEK PS

    CERN Document Server

    Takayama, Ken; Arakida, Yoshio; Horioka, Kazuhiko; Igarashi, Susumu; Iwashita, Taiki; Kawasaki, Atsushi; Kishiro, Junichi; Kono, Tadaaki; Koseki, Kunio; Nakamura, Eiji; Sakuda, Makoto; Sato, Hikaru; Shiho, Makoto; Shimosaki, Yoshito; Shirakata, Masashi; Sueno, Tsuyoshi; Tokuchi, Akira; Torikai, Kota; Toyama, Takeshi; Wake, Masayoshi; Watanabe, Masao; Yamane, Isao

    2005-01-01

    A single bunch trapped in an RF bucket was accelerated by induction devices from 500 MeV to 8GeV beyond transition energy in the KEK-PS. This is the first demonstration of induction acceleration in a high energy circular ring. The acceleration was confirmed by measuring a temporal evolution of the RF phase through an entire acceleration.* Key devices in an induction acceleration system are an induction accelerating cavity capable of generating an induced voltage of 2kV/cell, a pulse modulator to drive the cavity (switching driver), and a DSP system to control gate signals for switching. Their remarkable characteristics are its repetition ratio of about 1MHz and duty factor of 50%. All devices have been newly developed at KEK so as to meet this requirement. The pulse modulator employing MOSFETs as switching elements is connected with the accelerating cavity through a long transmission cable in order to avoid a high-dose irradiation in the accelerator tunnel. The induction system has been running beyond more th...

  5. An induction Linac approach to phase rotation of a muon bunch in the production region of μ+-μ- colliders

    International Nuclear Information System (INIS)

    Turner, W.C.

    1995-01-01

    The possibility of using an induction linac for phase rotation, or equivalently flattening the head to tail mean energy sweep, of a muon bunch in the production region of a μ + - μ - is examined. Axial spreading of an accelerating bunch is analyzed and the form of appropriate induction cell voltage waveforms is derived. A set of parametric equations for the induction accelerator structure is given and specific solutions are presented which demonstrate the technological feasibility of the induction linac approach to phase rotation

  6. Self-modulation instability of a long proton bunch in plasmas

    CERN Document Server

    Kumar, Naveen; Lotov, Konstantin

    2010-01-01

    An analytical model for the self-modulation instability of a long relativistic proton bunch propagating in uniform plasmas is developed. The self-modulated proton bunch resonantly excites a large amplitude plasma wave (wake field), which can be used for acceleration of plasma electrons. Analytical expressions for the linear growth rate and the number of exponentiations are given. We use the full three-dimensional particle-in-cell (PIC) simulations to study the beam self-modulation and the transition to the nonlinear stage. It is shown that the self-modulation of the proton bunch competes with the hosing instability which tends to destroy the plasma wave. A method is proposed and studied through PIC simulations to circumvent this problem which relies on the seeding of the self-modulation instability in the bunch.

  7. Modulated electron bunch with amplitude front tilt in an undulator

    International Nuclear Information System (INIS)

    Geloni, Gianluca; Kocharyan, Vitali; Saldin, Evgeni

    2015-12-01

    In a previous paper we discussed the physics of a microbunched electron beam kicked by the dipole field of a corrector magnet by describing the kinematics of coherent undulator radiation after the kick. We demonstrated that the effect of aberration of light supplies the basis for understanding phenomena like the deflection of coherent undulator radiation by a dipole magnet. We illustrated this fact by examining the operation of an XFEL under the steady state assumption, that is a harmonic time dependence. We argued that in this particular case the microbunch front tilt has no objective meaning; in other words, there is no experiment that can discriminate whether an electron beam is endowed with a microbunch front tilt of not. In this paper we extend our considerations to time-dependent phenomena related with a finite electron bunch duration, or SASE mode of operation. We focus our attention on the spatiotemporal distortions of an X-ray pulse. Spatiotemporal coupling arises naturally in coherent undulator radiation behind the kick, because the deflection process involves the introduction of a tilt of the bunch profile. This tilt of the bunch profile leads to radiation pulse front tilt, which is equivalent to angular dispersion of the output radiation. We remark that our exact results can potentially be useful to developers of new generation XFEL codes for cross-checking their results.

  8. Induction accelerator test module for HIF

    International Nuclear Information System (INIS)

    Faltens, A.

    1991-04-01

    An induction linac test module suitable for investigating the drive requirements and the longitudinal coupling impedance of a high-power ion induction linac has been constructed by the Heavy Ion Fusion (HIF) group at LBL. The induction linac heavy ion driver for inertial confinement fusion (ICF) as presently envisioned uses multiple parallel beams which are transported in separate focusing channels but accelerated together in the induction modules. The resulting induction modules consequently have large beam apertures-1--2 meters in diameter- and correspondingly large outside diameters. The module geometry is related to a low-frequency ''gap capacity'' and high-frequency structural resonances, which are affected by the magnetic core loading and the module pulser impedance. A description of the test module and preliminary results are presented. 3 figs

  9. First Observation of the Seeded Proton Bunch Self-Modulation in Plasma

    CERN Document Server

    AUTHOR|(CDS)2093171; Vincke, Helmut

    In this thesis I observe experimentally and study in simulations the seeded selfmodulation of a relativistic proton bunch in AWAKE, the Advanced Proton Driven Plasma Wakefield Acceleration Experiment. The 400 GeV/c proton bunch from the CERN SPS with a rms length of 12 cm propagates in a 10m long plasma with a density adjustable between 2-10x10^14 electrons/cm3. The seeded self-modulation process results in focusing and defocusing of the protons, thereby forming a bunch train that resonantly drives wakefields to large amplitudes. I use the two-screen measurement setup, to observe the result of the proton bunch self-modulation and to learn about its physics (i.e. growth of the process). The idea is to obtain images of protons that were defocused by the transverse wakefields, 2 and 10m downstream the end of the plasma. From these images I determine the maximum transverse momentum of the defocused protons as well as infer their point of origin along the plasma. I use simulations to guide the understanding of the...

  10. NLC Hybrid Solid State Induction Modulator

    CERN Document Server

    Cassel, R L; Pappas, G C; Delamare, J E

    2004-01-01

    The Next Linear Collider accelerator proposal at SLAC requires a high efficiency, highly reliable, and low cost pulsed power modulator to drive the X-band klystrons. The original NLC envisions a solid state induction modulator design to drive up to 8 klystrons to 500 kV for 3 μs at 120 PPS with one modulator delivering greater than 1,000 MW pulse, at 500 kW average. A change in RF compression techniques resulted in only two klystrons needed pulsing per modulator at a reduced pulse width of 1.6 μsec or approximately 250 MW of the pulsed power and 80 kW of average powers. A prototype Design for Manufacturability (DFM) 8-pack modulator was under construction at the time of the change, so a redirection of modulator design was in order. To utilities the equipment which had already be fabricated, a hybrid modulator was designed and constructed using the DFM induction modulator parts and a conventional pulse transformer. The construction and performance of this hybrid two klystron Induction modul...

  11. Investigations on a Novel Inductive Concept Frequency Technique for the Grading of Oil Palm Fresh Fruit Bunches

    Directory of Open Access Journals (Sweden)

    Kunihisa Tashiro

    2013-02-01

    Full Text Available From the Malaysian harvester’s perspective, the determination of the ripeness of the oil palm (FFB is a critical factor to maximize palm oil production. A preliminary study of a novel oil palm fruit sensor to detect the maturity of oil palm fruit bunches is presented. To optimize the functionality of the sensor, the frequency characteristics of air coils of various diameters are investigated to determine their inductance and resonant characteristics. Sixteen samples from two categories, namely ripe oil palm fruitlets and unripe oil palm fruitlets, are tested from 100 Hz up to 100 MHz frequency. The results showed the inductance and resonant characteristics of the air coil sensors display significant changes among the samples of each category. The investigations on the frequency characteristics of the sensor air coils are studied to observe the effect of variations in the coil diameter. The effect of coil diameter yields a significant 0.02643 MHz difference between unripe samples to air and 0.01084 MHz for ripe samples to air. The designed sensor exhibits significant potential in determining the maturity of oil palm fruits.

  12. Power module assembly with reduced inductance

    Energy Technology Data Exchange (ETDEWEB)

    Ward, Terence G.; Stancu, Constantin C.; Jaksic, Marko; Mann, Brooks S.

    2018-03-13

    A power module assembly has a plurality of electrically conducting layers, including a first layer and a third layer. One or more electrically insulating layers are operatively connected to each of the plurality of electrically conducting layers. The electrically insulating layers include a second layer positioned between and configured to electrically isolate the first and the third layers. The first layer is configured to carry a first current flowing in a first direction. The third layer is configured to carry a second current flowing in a second direction opposite to the first direction, thereby reducing an inductance of the assembly. The electrically insulating layers may include a fourth layer positioned between and configured to electrically isolate the third layer and a fifth layer. The assembly results in a combined substrate and heat sink structure. The assembly eliminates the requirements for connections between separate substrate and heat sink structures.

  13. Modeling of a Stacked Power Module for Parasitic Inductance Extraction

    Science.gov (United States)

    2017-09-15

    ARL-TR-8138 ● SEP 2017 US Army Research Laboratory Modeling of a Stacked Power Module for Parasitic Inductance Extraction by...not return it to the originator. ARL-TR-8138 ● SEP 2017 US Army Research Laboratory Modeling of a Stacked Power Module for... Power Module for Parasitic Inductance Extraction 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Steven Kaplan

  14. Bunch by bunch feedback systems

    International Nuclear Information System (INIS)

    Tobiyama, Makoto

    2006-01-01

    Outlines of bunch-by-bunch feedback systems for suppressing multibunch instabilities in electron/positron storage rings are presented. The design principles and functions of the feedback components are reviewed. Recent topics of applying very fast and dense FPGA as feedback signal processor are also shown. (author)

  15. Bunch Length Measurements in SPEAR3

    Energy Technology Data Exchange (ETDEWEB)

    Corbett, W.J.; Fisher, A.; Huang, X.; Safranek, J.; Sebek, J.; /SLAC; Lumpkin, A.; /Argonne; Sannibale, F.; /LBL, Berkeley; Mok, W.; /Unlisted

    2007-11-28

    A series of bunch length measurements were made in SPEAR3 for two different machine optics. In the achromatic optics the bunch length increases from the low-current value of 16.6ps rms to about 30ps at 25ma/bunch yielding an inductive impedance of -0.17{Omega}. Reducing the momentum compaction factor by a factor of {approx}60 [1] yields a low-current bunch length of {approx}4ps rms. In this paper we review the experimental setup and results.

  16. Updating the induction module from single-pulse to double-pulses

    International Nuclear Information System (INIS)

    Huang Ziping; Wang Huacen; Deng Jianjun

    2002-01-01

    A double-pulse Linear Induced Accelerator (LIA) module is reconstructed based on a usual simple-pulse LIA module. By changing the length of one of the cables between the inductive cell and the Blumlein pulse forming line, two induction pulses with 90 ns FWHM and 150 kV pulse voltage are generated by the ferrite cores inductive cell. The interval time of the pulses is adjustable by changing the lengths of the cable

  17. Single-bunch kicker pulser

    International Nuclear Information System (INIS)

    Frey, W.W.

    1983-01-01

    The single-bunch kicker magnet is powered by a capacitor discharge pulser. The ferrite-core magnet is used to kick out one of twelve proton bunches circulating in the AGS (Alternating Gradient Synchrotron) into the experimental area. The magnet current pulse has a half-sinusoid shape, with a peak current of 2800 A. The pulse current rises and falls to zero, with minimum undershoot, in 410 nsec to minimize effects on adjacent bunches. The magnet inductance is 1.0 μHy. The pulser is mounted on the kicker magnet in the AGS ring, and is exposed to ionizing radiation. The HVDC power supply, controls, monitoring, and auxiliary circuits are housed approximately 300 feet away external to the ring. A two-gap thyratron is used to discharge the energy storage capacitor. Two hydrogen diodes are series connected to function as an inverse diode

  18. Single-bunch kicker pulser

    Energy Technology Data Exchange (ETDEWEB)

    Frey, W.W.

    1983-01-01

    The single-bunch kicker magnet is powered by a capacitor discharge pulser. The ferrite-core magnet is used to kick out one of twelve proton bunches circulating in the AGS (Alternating Gradient Synchrotron) into the experimental area. The magnet current pulse has a half-sinusoid shape, with a peak current of 2800 A. The pulse current rises and falls to zero, with minimum undershoot, in 410 nsec to minimize effects on adjacent bunches. The magnet inductance is 1.0 ..mu..Hy. The pulser is mounted on the kicker magnet in the AGS ring, and is exposed to ionizing radiation. The HVDC power supply, controls, monitoring, and auxiliary circuits are housed approximately 300 feet away external to the ring. A two-gap thyratron is used to discharge the energy storage capacitor. Two hydrogen diodes are series connected to function as an inverse diode.

  19. Effect of different methods of pulse width modulation on power losses in an induction motor

    Science.gov (United States)

    Gulyaev, Alexander; Fokin, Dmitrii; Shuharev, Sergey; Ten, Evgenii

    2017-10-01

    We consider the calculation of modulation power losses in a system “induction motor-inverter” for various pulse width modulation (PWM) methods of the supply voltage. Presented values of modulation power losses are the result of modeling a system “DC link - two-level three-phase voltage inverter - induction motor - load”. In this study the power losses in a system “induction motor - inverter” are computed, as well as losses caused by higher harmonics of PWM supply voltage, followed by definition of active power consumed by the DC link for a specified value mechanical power on the induction motor shaft. Mechanical power was determined by the rotation speed and the torque on the motor shaft in various quasi-sinusoidal supply voltage PWM modes. These calculations reveal the best coefficient of performance (COP) in a system of a variable frequency drive (VFD) with independent voltage inverter controlled by induction motor PWM.

  20. Feasibility of applying home-made amorphous core to induction module

    International Nuclear Information System (INIS)

    Chen Sifu; Li Xin; Huang Ziping

    2008-01-01

    The application of the homemade 1K101 amorphous core in induction module is reported in this paper. The properties of magnetic, insulation and stability are studied with the cores. A pulse with pulse width of 120 ns (FWFM), flattop of 72 ns (±1%) and rise time of 17 ns can be obtained with single-pulse induction module. Triple-pulse with the rise time of 35 ns, flat-top of 60 ns (±1%) and pulse width of 120 ns (FWFM) was obtained when tested with a formal linear induction module at MHz repetition burst mode. The effective average flux swing of the amorphous core is about 1.41 T. The cores work well with triple-pulse of 282 kV. The properties of the cores are stable and suitable for induction module. (authors)

  1. Controller Design for Direct Torque Controlled Space Vector Modulated (DTC-SVM) Induction Motor Drives

    DEFF Research Database (Denmark)

    Zelechowski, M.; Kazmierkowski, M.P.; Blaabjerg, Frede

    2005-01-01

    In this paper two different methods of PI controllers for direct torque controlled-space vector modulated induction motor drives have been studied. The first one is simple method based only on symmetric optimum criterion. The second approach takes into account the full model of induction motor in...

  2. Photon anti bunching versus phantom anti bunching?

    International Nuclear Information System (INIS)

    Miranowicz, A.; Ekert, A.; Ekert, A.; Bajer, J.; Leonski, W.

    1997-01-01

    Photon anti bunching defined by two-time correlation functions has hitherto, to our best knowledge, been considered to constitute a unique, well defined effect. We show explicitly that this is by no means the case. We analyze two of the most famous definitions showing that both anti bunching and bunching effects according to one definition can be accompanied by arbitrary photon correlation effects according to another. As an example we discuss a model of parametric frequency conversion. (authors)

  3. Investigation of induction cells and modulator design for heavy ion accelerators

    International Nuclear Information System (INIS)

    Fong, C.G.; Reginato, L.R.

    1992-01-01

    The induction linear accelerator has been a leading candidate in the U.S. for the acceleration of high current heavy ion beams to initiate inertial confinement fusion (ICF). This paper describes the rather unique parameters derived from the accelerator beam dynamics, and addresses the design and development of accelerator induction cells and their modulators to be used in a near-term driver scaling experiment named the Induction Linac Systems Experiments (ILSE) planned for construction starting in 1994. Work is underway to develop the cells and their pulse modulators. Tradeoffs between the amorphous core material, pulse length, rise and fall time are made against efficiency, costs and technical risks are discussed

  4. Design of a low parasitic inductance SiC power module with double-sided cooling

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Fei [The University of Tennessee, Knoxville; Liang, Zhenxian [Cree Inc.; Wang, Fei [ORNL; Wang, Zhiqiang [ORNL

    2017-03-01

    In this paper, a low-parasitic inductance SiC power module with double-sided cooling is designed and compared with a baseline double-sided cooled module. With the unique 3D layout utilizing vertical interconnection, the power loop inductance is effectively reduced without sacrificing the thermal performance. Both simulations and experiments are carried out to validate the design. Q3D simulation results show a power loop inductance of 1.63 nH, verified by the experiment, indicating more than 60% reduction of power loop inductance compared with the baseline module. With 0Ω external gate resistance turn-off at 600V, the voltage overshoot is less than 9% of the bus voltage at a load of 44.6A.

  5. Measurement of short bunches

    International Nuclear Information System (INIS)

    Wang, D.X.

    1996-01-01

    In recent years, there has been increasing interest in short electron bunches for different applications such as short wavelength FELs, linear colliders, and advanced accelerators such as laser or plasma wakefield accelerators. One would like to meet various requirements such as high peak current, low momentum spread, high luminosity, small ratio of bunch length to plasma wavelength, and accurate timing. Meanwhile, recent development and advances in RF photoinjectors and various bunching schemes make it possible to generate very short electron bunches. Measuring the longitudinal profile and monitoring bunch length are critical to understand the bunching process and longitudinal beam dynamics, and to commission and operate such short bunch machines. In this paper, several commonly used measurement techniques for subpicosecond bunches and their relative advantages and disadvantages are discussed. As examples, bunch length related measurements at Jefferson Lab are presented. At Jefferson Lab, bunch lengths as short as 84 fs have been systematically measured using a zero-phasing technique. A highly sensitive Coherent Synchrotron Radiation (CSR) detector has been developed to noninvasively monitor bunch length for low charge bunches. Phase transfer function measurements provide a means of correcting RF phase drifts and reproducing RF phases to within a couple of tenths of a degree. The measurement results are in excellent agreement with simulations. A comprehensive bunch length control scheme is presented. (author)

  6. Measurement of short bunches

    International Nuclear Information System (INIS)

    Wang, D.X.

    1996-01-01

    In recent years, there has been increasing interest in short electron bunches for different applications such as short wavelength FELs, linear colliders, and advanced accelerators such as laser or plasma wakefield accelerators. One would like to meet various requirements such as high peak current, low momentum spread, high luminosity, small ratio of bunch length to plasma wavelength, and accurate timing. Meanwhile, recent development and advances in RF photoinjectors and various bunching schemes make it possible to generate very short electron bunches. Measuring the longitudinal profile and monitoring bunch length are critical to understand the bunching process and longitudinal beam dynamics, and to commission and operate such short bunch machines. In this paper, several commonly used measurement techniques for subpicosecond bunches and their relative advantages and disadvantages are discussed. As examples, bunch length related measurements at Jefferson lab are presented. At Jefferson Lab, bunch lengths s short as 84 fs have been systematically measured using a zero-phasing technique. A highly sensitive Coherent Synchrotron Radiation (CSR) detector has been developed to noninvasively monitor bunch length for low charge bunches. Phase transfer function measurements provide a means of correcting RF phase drifts and reproducing RF phases to within a couple of tenths of a degree. The measurement results are in excellent agreement with simulations. A comprehensive bunch length control scheme is presented

  7. Results of Preliminary Tests of PAR Bunch Cleaning

    CERN Document Server

    Yao, Chihyuan; Grelick, Arthur; Lumpkin, Alex H; Sereno, Nicholas S

    2005-01-01

    A particle accumulator ring (PAR) is used at the Advanced Photon Source (APS) to collect multiple linac bunches and compress them into a 0.3-ns (rms) single bunch for booster injection. A 9.77-MHz fundamental rf system and a 117.3-MHz harmonic rf system are employed for initial beam capture and bunch length compression. Satellite bunches with very low charge form due to rf phase drifts or beam loading change. These satellites, when injected into the booster and then into the storage ring (SR), cause bunch impurity at three buckets from the target bucket. Storage ring and booster bunch cleaning was tried but proved to be difficult due to the top-up mode of operation in the storage ring and tune drift in the booster synchrotron. Recently we implemented a PAR bunch-cleaning system with tune-modulated harmonic rf knockout. Preliminary tests gave a measured SR bunch purity of better than 10

  8. 100 kV, 80 kJ low-induction capacitor module

    International Nuclear Information System (INIS)

    Andrezen, A.B.; Burtsev, V.A.; Vodovozov, V.M.; Drozdov, A.A.; Makeev, G.M.

    1980-01-01

    A low induction capacitor module has been developed to investigate THETA- and Z-pinch plasma. Energy output time of the module lays in the microsecond range. The 100 kV, 80 kJ module is based on low-induction castor capasitors. The module is equipped with two solid dielectric dischargers, the system of discharger ignition protection system and automatic system for charging of capacitors. The module discharge period T 0 =5.6 μs. The capacitor module has been used in investigations of electric explosions of Al plane foils in the pulverized quartz. The overvoltage Usub(max)/Usub(o) approximately equal to 10 has been received at the maximum intensity of the electric field Esub(max) approximately equal to 12 kV/sm [ru

  9. Analog Amplitude Modulation of a High Voltage, Solid State Inductive Adder, Pulse Generator Using MOSFETS

    International Nuclear Information System (INIS)

    Gower, E J; Sullivan, J S

    2002-01-01

    High voltage, solid state, inductive adder, pulse generators have found increasing application as fast kicker pulse modulators for charged particle beams. The solid state, inductive adder, pulse generator is similar in operation to the linear induction accelerator. The main difference is that the solid state, adder couples energy by transformer action from multiple primaries to a voltage summing stalk, instead of an electron beam. Ideally, the inductive adder produces a rectangular voltage pulse at the load. In reality, there is usually some voltage variation at the load due to droop on primary circuit storage capacitors, or, temporal variations in the load impedance. Power MOSFET circuits have been developed to provide analog modulation of the output voltage amplitude of a solid state, inductive adder, pulse generator. The modulation is achieved by including MOSFET based, variable subtraction circuits in the multiple primary stack. The subtraction circuits can be used to compensate for voltage droop, or, to tailor the output pulse amplitude to provide a desired effect in the load. Power MOSFET subtraction circuits have been developed to modulate short, temporal (60-400 ns), voltage and current pulses. MOSFET devices have been tested up to 20 amps and 800 Volts with a band pass of 50 MHz. An analog modulation cell has been tested in a five cell high, voltage adder stack

  10. A bunch clock for the Advanced Photon Source

    International Nuclear Information System (INIS)

    Lenkszus, F.R.; Laird, R.J.

    1997-01-01

    A bunch clock timing module has been developed for use by Advanced Photon Source beamlines. The module provides bunch pattern and timing information that can be used to trigger beamline data collection equipment. The module is fully integrated into the control system software (EPICS) which automatically loads it with the storage ring fill pattern at injection time. Fast timing outputs (1 ns FWHM) for each stored bunch are generated using the storage ring low-level rf and revolution clock as input references. Fiber-optic-based transmitters and receivers are used to transmit a 352-MHz low-level rf reference to distributed bunch clock modules. The bunch clock module is a single-width VME module and may be installed in a VME crate located near beamline instrumentation. A prototype has been in use on the SRI CAT beamline for over a year. The design and integration into the control system timing software along with measured performance results are presented

  11. Development of bunch by bunch transverse feedback system at Hefei light source

    International Nuclear Information System (INIS)

    Wang Junhua; Zheng Kai; Li Weimin; Yang Yongliang; Huang Longjun; Chen Yuanbo; Zhou Zeran; Wang Lin; Liu Zeping; Sun Baogen; Ma Li; Cao Jianshe; Yue Junhui; Liu Dekang; Ye Kairong

    2008-01-01

    This paper has introduced the development of the transverse bunch-by-bunch measurement and feedback system, including the experiment of damping the coupled bunch instability. Some key technologies on the system have been introduced: the vector calculation module as a signal processing module used to adjust the phase of the feedback signals, the feedback kicker cavity and the notch filter used to filter the DC component and revolution frequencies component in a signal and save the feedback power. The result of the feedback experiment is mentioned: the instability oscillation was damped when the feedback system was on. (authors)

  12. Bunched beam neutralization

    International Nuclear Information System (INIS)

    Gammel, G.M.; Maschke, A.W.; Mobley, R.M.

    1979-01-01

    One of the steps involved in producing an intense ion beam from conventional accelerators for Heavy Ion Fusion (HIF) is beam bunching. To maintain space charge neutralized transport, neutralization must occur more quickly as the beam bunches. It has been demonstrated at BNL that a 60 mA proton beam from a 750 kV Cockcroft--Walton can be neutralized within a microsecond. The special problem in HIF is that the neutralization must occur in a time scale of nanoseconds. To study neutralization on a faster time scale, a 40 mA, 450 kV proton beam was bunched at 16 MHz. A biased Faraday cup sampled the bunched beam at the position where maximum bunching was nominally expected, about 2.5 meters from the buncher. Part of the drift region, about 1.8 meters, was occupied by a series of Gabor lenses. In addition to enhancing beam transport by transverse focussing, the background cloud of electrons in the lenses provided an extra degree of neutralization. With no lens, the best bunch factor was at least 20. Bunch factor is defined here as the ratio of the distance between bunches to the FWHM bunch length. With the lens, it was hoped that the increased plasma frequency would decrease the neutralization time and cause an increase in the bunch factor. In fact, with the lens, the instantaneous current increased about three times, but the bunch factor dropped to about 10. Even with the lens, the FWHM of the bunches at the position of maximum bunching was still comparable to or less than the oscillation period of the surrounding electron plasma. Thus, the electron density in the lens must increase before neutralization could be effective in this case, or bunching should be done at a lower frequency

  13. Development of a Respiratory Inductive Plethysmography Module Supporting Multiple Sensors for Wearable Systems

    Directory of Open Access Journals (Sweden)

    Zhengbo Zhang

    2012-09-01

    Full Text Available In this paper, we present an RIP module with the features of supporting multiple inductive sensors, no variable frequency LC oscillator, low power consumption, and automatic gain adjustment for each channel. Based on the method of inductance measurement without using a variable frequency LC oscillator, we further integrate pulse amplitude modulation and time division multiplexing scheme into a module to support multiple RIP sensors. All inductive sensors are excited by a high-frequency electric current periodically and momentarily, and the inductance of each sensor is measured during the time when the electric current is fed to it. To improve the amplitude response of the RIP sensors, we optimize the sensing unit with a matching capacitor parallel with each RIP sensor forming a frequency selection filter. Performance tests on the linearity of the output with cross-sectional area and the accuracy of respiratory volume estimation demonstrate good linearity and accurate lung volume estimation. Power consumption of this new RIP module with two sensors is very low. The performance of respiration measurement during movement is also evaluated. This RIP module is especially desirable for wearable systems with multiple RIP sensors for long-term respiration monitoring.

  14. Fuzzy Logic Controlled Solar Module for Driving Three- Phase Induction Motor

    Science.gov (United States)

    Afiqah Zainal, Nurul; Sooi Tat, Chan; Ajisman

    2016-02-01

    Renewable energy produced by solar module gives advantages for generated three- phase induction motor in remote area. But, solar module's ou tput is uncertain and complex. Fuzzy logic controller is one of controllers that can handle non-linear system and maximum power of solar module. Fuzzy logic controller used for Maximum Power Point Tracking (MPPT) technique to control Pulse-Width Modulation (PWM) for switching power electronics circuit. DC-DC boost converter used to boost up photovoltaic voltage to desired output and supply voltage source inverter which controlled by three-phase PWM generated by microcontroller. IGBT switched Voltage source inverter (VSI) produced alternating current (AC) voltage from direct current (DC) source to control speed of three-phase induction motor from boost converter output. Results showed that, the output power of solar module is optimized and controlled by using fuzzy logic controller. Besides that, the three-phase induction motor can be drive and control using VSI switching by the PWM signal generated by the fuzzy logic controller. This concluded that the non-linear system can be controlled and used in driving three-phase induction motor.

  15. Fuzzy Logic Controlled Solar Module for Driving Three- Phase Induction Motor

    International Nuclear Information System (INIS)

    Zainal, Nurul Afiqah; Tat, Chan Sooi; Ajisman

    2016-01-01

    Renewable energy produced by solar module gives advantages for generated three- phase induction motor in remote area. But, solar module's output is uncertain and complex. Fuzzy logic controller is one of controllers that can handle non-linear system and maximum power of solar module. Fuzzy logic controller used for Maximum Power Point Tracking (MPPT) technique to control Pulse-Width Modulation (PWM) for switching power electronics circuit. DC-DC boost converter used to boost up photovoltaic voltage to desired output and supply voltage source inverter which controlled by three-phase PWM generated by microcontroller. IGBT switched Voltage source inverter (VSI) produced alternating current (AC) voltage from direct current (DC) source to control speed of three-phase induction motor from boost converter output. Results showed that, the output power of solar module is optimized and controlled by using fuzzy logic controller. Besides that, the three-phase induction motor can be drive and control using VSI switching by the PWM signal generated by the fuzzy logic controller. This concluded that the non-linear system can be controlled and used in driving three-phase induction motor. (paper)

  16. Beam bunch feedback

    International Nuclear Information System (INIS)

    Lambertson, G.

    1995-09-01

    When the electromagnetic fields that are excited by the passage of a bundle of charged particles persist to act upon bunches that follow, then the motions of the bunches are coupled. This action between bunches circulating on a closed orbit can generate growing patterns of bunch excursions. Such growth can often be suppressed by feedback systems that detect the excursion and apply corrective forces to the bunches. To be addressed herein is feedback that acts on motions of the bunch body centers. In addition to being useful for suppressing the spontaneous growth of coupled-bunch motions, such feedback can be used to damp transients in bunches injected into an accelerator or storage ring; for hadrons which lack strong radiation damping, feedback is needed to avoid emittance growth through decoherence. Motions excited by noise in magnetic fields or accelerating rf can also be reduced by using this feedback. Whether the action is on motions that are transverse to the closed orbit or longitudinal, the arrangement is the same. Bunch position is detected by a pickup and that signal is processed and directed to a kicker that may act upon the same bunch or some other portion of the collective beam pattern. Transverse motion is an oscillation with angular frequency ν perpendicular ω o where ω o is the orbital frequency 2π line-integral o. Longitudinal synchrotron oscillation occurs at frequency ω s = ν s ω o . The former is much more rapid, ν perpendicular being on the order of 10 while ν s is typically about 10 minus 1 to 10 minus 2

  17. A Multi-Cycle Q-Modulation for Dynamic Optimization of Inductive Links.

    Science.gov (United States)

    Lee, Byunghun; Yeon, Pyungwoo; Ghovanloo, Maysam

    2016-08-01

    This paper presents a new method, called multi-cycle Q-modulation, which can be used in wireless power transmission (WPT) to modulate the quality factor (Q) of the receiver (Rx) coil and dynamically optimize the load impedance to maximize the power transfer efficiency (PTE) in two-coil links. A key advantage of the proposed method is that it can be easily implemented using off-the-shelf components without requiring fast switching at or above the carrier frequency, which is more suitable for integrated circuit design. Moreover, the proposed technique does not need any sophisticated synchronization between the power carrier and Q-modulation switching pulses. The multi-cycle Q-modulation is analyzed theoretically by a lumped circuit model, and verified in simulation and measurement using an off-the-shelf prototype. Automatic resonance tuning (ART) in the Rx, combined with multi-cycle Q-modulation helped maximizing PTE of the inductive link dynamically in the presence of environmental and loading variations, which can otherwise significantly degrade the PTE in multi-coil settings. In the prototype conventional 2-coil link, the proposed method increased the power amplifier (PA) plus inductive link efficiency from 4.8% to 16.5% at ( R L = 1 kΩ, d 23 = 3 cm), and from 23% to 28.2% at ( R L = 100 Ω, d 23 = 3 cm) after 11% change in the resonance capacitance, while delivering 168.1 mW to the load (PDL).

  18. Micro-bunching diagnostics for the IFEL by coherent transition radiation

    International Nuclear Information System (INIS)

    Liu, Y.; Cline, D.B.

    1996-10-01

    Here, we propose an effective method for detecting micro-bunching effects (10 fs bunch length) produced by the IFEL interaction, by measuring the CTR spectrum. The pre-bunching of an initially energy- modulated c- beam passing through a wiggler (IFEL interaction) is studied. Simulation shows that more than 40% of electrons are pre- bunched in the micro-bunches. The longitudinal distribution of an optically pre-bunched beam is Fourier analyzed to find the dominant harmonics contributing to the CTR. The CTR spectrum is calculated analytically for the IFEL situation. A detection system has been built to demonstrate this technique

  19. KEKB bunch feedback systems

    Energy Technology Data Exchange (ETDEWEB)

    Tobiyama, M; Kikutani, E [National Lab. for High Energy Physics, Tsukuba, Ibaraki (Japan)

    1996-08-01

    Design and the present status of the bunch by bunch feedback systems for KEKB rings are shown. The detection of the bunch oscillation are made with the phase detection for longitudinal plane, the AM/PM method for transverse plane. Two GHz component of the bunch signal which is extracted with an analog FIR filter is used for the detection. Hardware two-tap FIR filter systems to shift the phase of the oscillation by 90deg will be used for the longitudinal signal processing. The same system will be used with no filtering but with only digital delay for transverse system. The candidate for the kicker and the required maximum power are also estimated. (author)

  20. Longitudinal Diagnostics for Short Electron Beam Bunches

    Energy Technology Data Exchange (ETDEWEB)

    Loos, H.; /SLAC

    2010-06-11

    Single-pass free electron lasers require high peak currents from ultra-short electron bunches to reach saturation and an accurate measurement of bunch length and longitudinal bunch profile is necessary to control the bunch compression process from low to high beam energy. The various state-of-the-art diagnostics methods from ps to fs time scales using coherent radiation detection, RF deflection, and other techniques are presented. The use of linear accelerators as drivers for free electron lasers (FEL) and the advent of single-pass (SASE) FELs has driven the development of a wide range of diagnostic techniques for measuring the length and longitudinal distribution of short and ultra-short electron bunches. For SASE FELs the radiation power and the length of the undulator needed to achieve saturation depend strongly on the charge density of the electron beam. In the case of X-ray FELs, this requires the accelerator to produce ultra-high brightness beams with micron size transverse normalized emittances and peak currents of several kA through several stages of magnetic bunch compression. Different longitudinal diagnostics are employed to measure the peak current and bunch profile along these stages. The measurement techniques can be distinguished into different classes. Coherent methods detect the light emitted from the beam by some coherent radiation process (spectroscopic measurement), or directly measure the Coulomb field traveling with the beam (electro-optic). Phase space manipulation techniques map the time coordinate onto a transverse dimension and then use conventional transverse beam diagnostics (transverse deflector, rf zero-phasing). Further methods measure the profile or duration of an incoherent light pulse emitted by the bunch at wavelengths much shorted than the bunch length (streak camera, fluctuation technique) or modulate the electron beam at an optical wavelength and then generate a narrow bandwidth radiation pulse with the longitudinal profile of

  1. Ciprofloxacin and Trimethoprim Cause Phage Induction and Virulence Modulation in Staphylococcus aureus

    Science.gov (United States)

    Goerke, Christiane; Köller, Johanna; Wolz, Christiane

    2006-01-01

    In Staphylococcus aureus strains of human origin, phages which integrate into the chromosomal gene coding for β-hemolysin (hlb) are widely distributed. Most of them encode accessory virulence determinants such as staphylokinase (sak) or enterotoxins. Here, we analyzed the effects of ciprofloxacin and trimethoprim on phage induction and expression of phage-encoded virulence factors by using isolates from patients with cystic fibrosis for which the induction of hlb-converting phages was demonstrated in vivo (C. Goerke, S. Matias y Papenberg, S. Dasbach, K. Dietz, R. Ziebach, B. C. Kahl, and C. Wolz, J. Infect. Dis. 189:724-734, 2004) as well as a φ13 lysogen of phage-cured strain 8325-4. Treatment of lysogens with subinhibitory concentrations of either antibiotic resulted in (i) delysogenization of strains resembling the isolates picked up after chronic lung infection and (ii) replication of phages in the bacterial host in a dose-dependent manner. Ciprofloxacin treatment resulted in enhanced recA transcription, indicating involvement of the SOS response in phage mobilization. Induction of φ13 was linked to elevated expression of the phage-encoded virulence gene sak, chiefly due to the activation of latent phage promoters. In summary, we could show the induction of hlb-converting phages and a subsequent virulence modulation of the host bacterium by ciprofloxacin and trimethoprim. PMID:16377683

  2. Hollow bunches production

    CERN Document Server

    Hancock, S

    2017-01-01

    Hollow bunches address the issue of high-brightnessbeams suffering from transverse emittance growth in a strongspace charge regime. During the Proton Synchrotron (PS)injection plateau, the negative space charge tune shift canpush the beam onto theQy=6integer resonance. Modify-ing the longitudinal bunch profile in order to reduce the peakline charge density alleviates the detrimental impact of spacecharge. To this end we first produce longitudinally hollowphase space distributions in the PS Booster by exciting aparametric resonance with the phase loop feedback system.These inherently flat bunches are then transferred to the PS,where the beam becomes less prone to the emittance growthcaused by the integer resonance.During the late 2016 machine development sessions inthe PS Booster we profited from solved issues from 2015and managed to reliably extract hollow bunches of1.3eVsmatched longitudinal area. Furthermore, first results to cre-ate hollow bunches with larger longitudinal emittances to-wards the LHC Inject...

  3. Bunch-by-bunch feedback for PEP II

    International Nuclear Information System (INIS)

    Oxoby, G.; Claus, R.; Eisen, N.; Fox, J.; Hindi, H.; Hoeflich, J.; Olsen, J.; Sapozhnikov, L.; Linscott, I.

    1993-01-01

    The proposed PEP II B factory at SLAC requires a feedback to damp out longitudinal synchrotron oscillations. A time domain, downsampled, bunch-by-bunch feedback system in which each bunch is treated as an oscillator being driven by disturbances from other bunches is presented as we review the evolution of the system design. Results from a synchrotron oscillation damping experiment conducted at the SLAC/SSRL/SPEAR ring are also presented in this paper

  4. Multi-bunch energy compensation in the NLC bunch compressor

    International Nuclear Information System (INIS)

    Zimmermann, F.; Raubenheimer, T.O.; Thomson, K.A.

    1996-06-01

    The task of the NLC bunch compressor is to reduce the length of each bunch in a train of 90 bunches from 4 mm, at extraction from the damping ring, to about 100 μm, suitable for injection into the X-band main linac. This task is complicated by longitudinal long-range wake fields and the multi-bunch beam loading in the various accelerating sections of the compressor. One possible approach to compensate the multi-bunch beam loading is to add two RF systems with slightly different frequencies (' Δf' scheme) to each accelerating section, as first proposed by Kikuchi. This paper summarizes the choice of parameters for three such compensating sections, and presents simulation results of combined single- and multi-bunch dynamics for four different NLC versions. The multi-bunch energy compensation is shown to be straightforward and its performance to be satisfactory

  5. Single bunch fast longitudinal instability

    International Nuclear Information System (INIS)

    Wang, J.M.; Pellegrini, C.

    1979-01-01

    Single bunch longitudinal instability producing an increase of the bunch area have been observed in proton synchrotron and storage rings. Signals at microwave frequencies are observed during the bunch blow-up and because of this the effect has been called the microwave instability. A similar increase in bunch area is observed also in electron storage rings, where it is usually referred to as the bunch lengthening effect. This paper is an attempt to obtain a more general theory of this effect. Here we describe the model used and the method of calculation, together with some general results. More detailed results will be given in another paper. The main result is the derivation of a condition for the existence of a fast longitudinal bunch blow-up. This condition is a generalized threshold formula, showing explicitly the dependence on the bunch energy spread and length. This condition is qualitatively in agreement with Boussard's suggestion

  6. Single bunch fast longitudinal instability

    International Nuclear Information System (INIS)

    Wang, J.M.; Pellegrini, C.

    1979-01-01

    Single bunch longitudinal instability producing an increase of the bunch areas has been observed in proton synchrotron and storage rings. Singals at microwave frequencies are observed during the bunch blow-up and because of this the effect has been called the microwave instability. A similar increase in bunch area is observed also in electron storage rings, where it is usually referred to as the bunch lengthening effect. This paper is an attempt to obtain a more general theory of this effect. Here we describe the model used and the method of calculation, together with some general results. The main result of this paper is the derivation of a condition for the existence of a fast longitudinal bunch blow-up. This condition is a generalized threshold formula, showing explicitly the dependence on the bunch energy spread and length

  7. Bunch length and impedance measurements in SPEAR

    International Nuclear Information System (INIS)

    Bane, K.; Donald, M.; Hofmann, A.; Jowett, J.; Lockman, W.; Morton, P.; Stege, R.; Spence, W.; Wilson, P.

    1988-05-01

    Subsequent to an extensive smoothing of the vacuum chamber a comprehensive study of the SPEAR impedance was undertaken. Bunch length, synchrotron quadrupole mode frequency, and parasitic mode loss were measured as functions of beam current. The results showed that, although the gross longitudinal impedance had indeed been reduced, the 'capacitive' component had also decreased relative to the 'inductive'--to the extent that previously compensated potential well distortion now induced bunch lengthening at low currents, and the turbulent threshold had actually been lowered. A specially designed multi-cell disc-loaded 'capacitor' cavity was shown to be capable of removing this effect by restoring the original compensation. A model of the new SPEAR impedance is also obtained. 7 refs., 6 figs

  8. Bunch length and impedance measurements in SPEAR

    International Nuclear Information System (INIS)

    Bane, K.; Donald, M.; Morton, P.; Stege, R.; Spence, W.; Wilson, P.; Hofmann, A.; Jowett, J.; Lockman, W.

    1988-01-01

    Subsequent to an extensive smoothing of the vacuum chamber a comprehensive study of the SPEAR impedance was undertaken. Bunch length, synchrotron quadrupole mode frequency, and parasitic mode loss were measured as functions of beam current. This paper shows that although the gross longitudinal impedance had indeed been reduced, the capacitive component had also decreased relative to the inductive - to the extent that previously compensated potential well distortion now induced bunch lengthening at low currents, and the turbulent threshold had actually been lowered. A specially designed multi-cell disc-loaded capacitor cavity was shown to be capable of removing this effect by restoring the original compensation. A model of the new SPEAR impedance is also obtained

  9. Performance analysis of variable speed multiphase induction motor with pole phase modulation

    Directory of Open Access Journals (Sweden)

    Liu Huijuan

    2016-09-01

    Full Text Available The pole phase modulation (PPM technique is an effective method to extend speed range and torque capabilities for an integrated starter and hybrid electric vehicles applications. In this paper, the five pole-phase combination types of a multiphase induction motor (IM with 36 stator slots and 36 stator conductors are presented and compared quantitatively by using the time-stepping finite element method (TS-FEM. The 36 stator conductors of the proposed multiphase IM are fed by a 36 leg inverter and the current phase angle and amplitude of each stator conductor can be controlled independently. This paper focuses on the winding connection, the PPM technique and the performance comparative analysis of each pole-phase combination types of the proposed multiphase IM. The flux distribution, air-gap flux density, output torque, core losses and efficiency of five pole-phase combination types have been investigated.

  10. Micro-bunching diagnostics for the ICA by coherent transition radiation

    International Nuclear Information System (INIS)

    Liu, Y.; Bogacz, S.A.; Cline, D.B.; Wang, X.J.; Pogorelsky, I.V.; Kimura, W.D.

    1995-01-01

    Here, the authors propose an effective method to detect micro-bunching effects (10 fs bunch length), produced by the ICA interaction, by using the CTR spectrum. The re-bunching of initially energy modulated e-beam passing through a Hydrogen gas cell (ICA interaction) is studied via a Monte Carlo simulation code (STI), as well as in a space-charge dominated region by a multi-particle time domain tracking code (PARMELA). The results show that even in a strong space-charge dominated region the re-bunching effect is still very pronounced. The erosion of bunching due to the space-charge defocusing washes out the final bunching peak only by about 10% (FWHM). The longitudinal distribution of a micro-bunched beam is Fourier analyzed to find the dominant harmonics contributing to the CTR. The CTR spectrum is calculated analytically for the ICA situation. A schematic of the experimental set up is also proposed

  11. Electro-Magnetic Bunch Length Measurement in LEP

    CERN Document Server

    Vos, L

    1998-01-01

    Bunch lengths between 3 and 12 mm have been measured routinely in LEP in 1997 with a small (7 mm diameter) button electrode. The measurement method is based on the spectral analysis of the electrode signal and relies on the fact that the transfer function of the complete set-up, including the signal cable, can be computed rather exactly thus eliminating the need for external calibration. The information of beam intensity is recovered as a by-product. It provides an interesting internal validation of the measurement by comparison with the normal intensity measurement. The system has been used to detect subtle but real bunch length changes with bunch intensity which can be attributed to the inductive impedance in LEP. A value for the imaginary (inductive) longitudinal impedance is derived from the observations. An indication for the resistive part of the impedance is given as well.

  12. Differential growth factor induction and modulation of human gastric epithelial regeneration

    International Nuclear Information System (INIS)

    Tetreault, Marie-Pier; Chailler, Pierre; Rivard, Nathalie; Menard, Daniel

    2005-01-01

    While several autocrine/paracrine growth factors (GFs) can all stimulate epithelial regeneration in experimentally wounded primary gastric cultures, clinical relevance for their non-redundant cooperative actions in human gastric ulcer healing is suggested by the sequential pattern of GF gene induction in vivo. Using new HGE cell lines able to form a coherent monolayer with tight junctions as well as using primary human gastric epithelial cultures, we show that EGF, TGFα, HGF and IGFs accelerate epithelial restitution upon wounding, independently of the TGFβ pathway (as opposed to intestinal cells). However, they differently modulate cell behavior: TGFα exerts strong effects (even more than EGF) on cytoplasmic spreading and non-oriented protruding activity of bordering cells whereas HGF preferentially coordinates single lamella formation, cell elongation and migration into the wound. IGF-I and IGF-II rather induce the alignment of bordering cells and maintain a compact monolayer front. The number of mitotic cells maximally increases with EGF, followed by TGFα and IGF-I,-II. The current study demonstrates that GFs differentially regulate the regeneration of human gastric epithelial cells through specific modulation of cell shape adaptation, migration and proliferation, further stressing that a coordination of GF activities would be necessary for the normal progression of post-wounding epithelial repair

  13. Measurement of femtosecond electron bunches

    International Nuclear Information System (INIS)

    Wang, D. X.; Krafft, G. A.; Sinclair, C. K.

    1997-01-01

    Bunch lengths as short as 84 fs (rms) have been measured at Jefferson Lab using a zero-phasing RF technique. To the best of our knowledge, this is the first accurate bunch length measurement in this regime. In this letter, an analytical approach for computing the longitudinal distribution function and bunch length is described for arbitrary longitudinal and transverse distributions. The measurement results are presented, which are in excellent agreement with numerical simulations

  14. Beam induced heating reduction by bunch flattening

    CERN Document Server

    Argyropoulos, T; Esteban Müller, JF; Jakobsen, S; Mastoridis, T; Metral, E; Mounet, N; Papotti, G; Pieloni, T; Salvant, B; Shaposhnikova, E; Timko, H

    2014-01-01

    The main purpose of this MD was to modify the beam induced heating on some critical LHC components by flattening the bunch distribution by applying an RF phase modulation. In this way, the beam spectrum was modified so that the power spectral density is reduced at low frequencies (below 1.1 GHz), which is the band of frequencies where the beam interaction with different component impedances is most critical. We present temperature measurements showing the beneficial effect of this latter distribution on some of the monitored devices. Longitudinal peak detected Schottky spectrum was also acquired during the first part of the MD with the intention of estimating the synchrotron frequency shift due to the reactive part of the longitudinal impedance. In the second part of the MD, an attempt to cure the transverse instability during the beta-squeeze was done by reducing the RF voltage to lengthen the bunches and enhance Landau Damping.

  15. Low-inductance switch and capacitor energy storage modules made of packages of industrial condensers IK50-3

    International Nuclear Information System (INIS)

    Bykov, Yu A; Krastelev, E G; Sedin, A A; Feduschak, V F

    2017-01-01

    A low-inductance module of a high-current capacitive energy storage with an operating voltage of 40 kV is developed. The design of the module is based on the application of capacitive sections of the industrial condenser IK50-3. The module includes two capacitors of 0.35 μF each, one common low-jitter triggered gas switch and 2 groups of output cables of 4 from each capacitor. A bus bars topology developed for the switch and cables connections provides a small total inductance of the discharge circuit, for the module with the output cables KVIM of 0.5 m long, it is lower than 40 nH. The set of 10 modules is now used for driving the 20 stages linear transformer for a fast charging of the pulse forming line of the high-current nanosecond accelerator. A design of the module and the results of tests of a single module and a set of 10 are presented. (paper)

  16. Bunching phase and constraints on echo enabled harmonic generation

    Science.gov (United States)

    Hemsing, E.

    2018-05-01

    A simple mathematical description is developed for the bunching spectrum in echo enabled harmonic generation (EEHG) that incorporates the effect of additional electron beam energy modulations. Under common assumptions, they are shown to contribute purely through the phase of the longitudinal bunching factor, which allows the spectral moments of the bunching to be calculated directly from the known energy modulations. In particular, the second moment (spectral bandwidth) serves as simple constraint on the amplitude of the energy modulations to maintain a transform-limited seed. We show that, in general, the impact on the spectrum of energy distortions that develop between the EEHG chicanes scales like the harmonic number compared to distortions that occur upstream. This may limit the parameters that will allow EEHG to reach short wavelengths in high brightness FELs.

  17. Optimization of a train of bunches for plasma wakefield acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Martorelli, Roberto

    2016-05-10

    Particle accelerators are a fundamental instrument for the understanding of fundamental mechanism in nature. The need of always higher energies for the particle beams requires a huge increase of the sizes of the accelerators using the actual technology. Moreover the highest energies are achieved nowadays by circular colliders, not perfectly suitable for acceleration of electrons and positrons due to the radiation losses. In order to overcome this problem a new branch of physics studying alternative technique for particle acceleration has been developed. Among the various alternatives a promising one is the plasma wakefield acceleration (PWFA), in which a driver bunch interacts with a cold background plasma, exciting a plasma wave. The electric field of the plasma wave is then used for the acceleration of a second bunch. Such a mechanism allows to reach fields strength far beyond currently available, limited by the dielectric strength of the material. Among the different driver configurations, a promising one is the use of a modulated beam, namely a train of bunches, that provides a coherent interference among the electric fields generated by the single bunches. Such mechanism is subjected to a renewed interest in view of the forthcoming AWAKE experiment at CERN in which the long proton beam produced at the SPS facility is used as a driver. This possibility is achieved thanks to the onset of the self-modulation instability that modulates the long beam in a train of approximately 100 bunches. In order to accelerate the witness bunch to high energies is necessary on the other hand an efficient exchange of energy from the driver to the accelerated bunch, as well as a long duration of the driver so that can propagates for kilometers. This thesis deals with this two last aspects. The aim of this work is to provide an optimization for the modulated driver in order to improve specific features of the PWFA. This work shows the possibility to achieve an improved efficiency

  18. Induction of salt tolerance in Azolla microphylla Kaulf through modulation of antioxidant enzymes and ion transport.

    Science.gov (United States)

    Abraham, Gerard; Dhar, Dolly Wattal

    2010-09-01

    Azolla microphylla plants exposed directly to NaCl (13 dsm(-1)) did not survive the salinity treatment beyond a period of one day, whereas plants exposed directly to 4 and 9 dsm(-1) NaCl were able to grow and produce biomass. However, plants pre-exposed to NaCl (2 dsm(-1)) for 7 days on subsequent exposure to 13 dsm(-1) NaCl were able to grow and produce biomass although at a slow rate and are hereinafter designated as pre-exposed plants. The pre-exposed and directly exposed plants distinctly differed in their response to salt in terms of lipid peroxidation, proline accumulation, activity of antioxidant enzymes, such as SOD, APX, and CAT, and Na(+)/K(+) ratio. Efficient modulation of antioxidant enzymes coupled with regulation of ion transport play an important role in the induction of salt tolerance. Results show that it is possible to induce salt adaptation in A. microphylla by pre-exposing them to low concentrations of NaCl.

  19. Nanoparticle curcumin ameliorates experimental colitis via modulation of gut microbiota and induction of regulatory T cells.

    Directory of Open Access Journals (Sweden)

    Masashi Ohno

    Full Text Available Curcumin is a hydrophobic polyphenol derived from turmeric, a traditional Indian spice. Curcumin exhibits various biological functions, but its clinical application is limited due to its poor absorbability after oral administration. A newly developed nanoparticle curcumin shows improved absorbability in vivo. In this study, we examined the effects of nanoparticle curcumin (named Theracurmin on experimental colitis in mice.BALB/c mice were fed with 3% dextran sulfate sodium (DSS in water. Mucosal cytokine expression and lymphocyte subpopulation were analyzed by real-time PCR and flow cytometry, respectively. The profile of the gut microbiota was analyzed by real-time PCR.Treatment with nanoparticle curcumin significantly attenuated body weight loss, disease activity index, histological colitis score and significantly improved mucosal permeability. Immunoblot analysis showed that NF-κB activation in colonic epithelial cells was significantly suppressed by treatment with nanoparticle curcumin. Mucosal mRNA expression of inflammatory mediators was significantly suppressed by treatment with nanoparticle curcumin. Treatment with nanoparticle curcumin increased the abundance of butyrate-producing bacteria and fecal butyrate level. This was accompanied by increased expansion of CD4+ Foxp3+ regulatory T cells and CD103+ CD8α- regulatory dendritic cells in the colonic mucosa.Treatment with nanoparticle curcumin suppressed the development of DSS-induced colitis potentially via modulation of gut microbial structure. These responses were associated with induction of mucosal immune cells with regulatory properties. Nanoparticle curcumin is one of the promising candidates as a therapeutic option for the treatment of IBD.

  20. CEBAF Upgrade Bunch Length Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, Mahmoud [Old Dominion Univ., Norfolk, VA (United States)

    2016-05-01

    Many accelerators use short electron bunches and measuring the bunch length is important for efficient operations. CEBAF needs a suitable bunch length because bunches that are too long will result in beam interruption to the halls due to excessive energy spread and beam loss. In this work, bunch length is measured by invasive and non-invasive techniques at different beam energies. Two new measurement techniques have been commissioned; a harmonic cavity showed good results compared to expectations from simulation, and a real time interferometer is commissioned and first checkouts were performed. Three other techniques were used for measurements and comparison purposes without modifying the old procedures. Two of them can be used when the beam is not compressed longitudinally while the other one, the synchrotron light monitor, can be used with compressed or uncompressed beam.

  1. Analysis of bunch by bunch oscillations with bunch trains at injection into LHC at 25 ns bunch spacing

    CERN Document Server

    Bartosik, H

    2012-01-01

    An MD on August 26, 2011 was dedicated to injection studies of bunch trains with 25 ns spacing and nominal intensity of approximately 1×10(11) protons per bunch. Due to an electrical glitch, the MD was stopped after two attempts of injecting a train of 48 bunches for beam 2. Both injections were aborted after less than 0.1 s. In particular, the first attempt with transverse damper on was dumped after 1000 turns while the second attempt with transverse damper off was dumped after 500 turns only. In this note, an analysis of the bunch by bunch oscillation data recorded with the post-mortem system from the transverse damper is presented. The presented data clearly shows the presence of instabilities that affect mainly the second half of the batch. This is compatible with what would be expected qualitatively in the presence of the electron cloud effect.

  2. High current induction linacs

    International Nuclear Information System (INIS)

    Barletta, W.; Faltens, A.; Henestroza, E.; Lee, E.

    1994-07-01

    Induction linacs are among the most powerful accelerators in existence. They have accelerated electron bunches of several kiloamperes, and are being investigated as drivers for heavy ion driven inertial confinement fusion (HIF), which requires peak beam currents of kiloamperes and average beam powers of some tens of megawatts. The requirement for waste transmutation with an 800 MeV proton or deuteron beam with an average current of 50 mA and an average power of 40 MW lies midway between the electron machines and the heavy ion machines in overall difficulty. Much of the technology and understanding of beam physics carries over from the previous machines to the new requirements. The induction linac allows use of a very large beam aperture, which may turn out to be crucial to reducing beam loss and machine activation from the beam halo. The major issues addressed here are transport of high intensity beams, availability of sources, efficiency of acceleration, and the state of the needed technology for the waste treatment application. Because of the transformer-like action of an induction core and the accompanying magnetizing current, induction linacs make the most economic sense and have the highest efficiencies with large beam currents. Based on present understanding of beam transport limits, induction core magnetizing current requirements, and pulse modulators, the efficiencies could be very high. The study of beam transport at high intensities has been the major activity of the HIF community. Beam transport and sources are limiting at low energies but are not significant constraints at the higher energies. As will be shown, the proton beams will be space-charge-dominated, for which the emittance has only a minor effect on the overall beam diameter but does determine the density falloff at the beam edge

  3. A Main Ring bunch length monitor by detecting two frequency components of the beam

    International Nuclear Information System (INIS)

    Ieiri, T.; Jackson, G.

    1989-01-01

    The bunch length is measured by detecting two revolution frequency harmonics of the beam and taking the ratio of their amplitudes. Two heterodyne receivers have been made to direct them, one at 53MHz and the other at 159MHz. These signals are picked-up by a stripline detector. An analog circuit provides a signal proportional to the bunch length. The monitor measures variation of the bunch length as a function of time in the Main Ring. The measured signal, which sometimes shows that the bunches are tumbling in phase space, can be damped by feedback to the RF amplitude modulator. 9 refs., 12 figs., 1 tab

  4. PF-KO system for single bunch mode operation of a storage ring

    International Nuclear Information System (INIS)

    Ohgaki, H.; Sugiyama, S.; Mikado, T.; Chiwaki, M.; Yamada, K.; Suzuki, R.; Sei, N.; Noguchi, T.; Yamazaki, T.

    1994-01-01

    A new RF-KO (RF knockout) system for the single bunch mode operation of a storage ring has been developed. The knockout signal is modulated by the sum signal of the RF acceleration frequency of the storage ring and a bunch selection signal. We do not need any special device or a timing unit with this method. We obtain a high purity of bunch structure in a short knock out time. The single bunch impurity of 0.2% has been achieved. (author)

  5. Characterestics of pico-second single bunch at the S-band linear accelerator

    International Nuclear Information System (INIS)

    Uesaka, Mitsuru; Kozawa, Takahiro; Kobayashi, Toshiaki; Ueda, Toru; Miya, Kenzo

    1994-01-01

    Measurement of the bunch structure of a pico-second single bunch was performed using a femto-second streak camera at the S-band linear accelerator of the University of Tokyo. The aim of this research is to investigate the feasibility of the generation of a femto-second single bunch at the S-band linac. The details of the bunch structure and energy spectrum of an original single bunch were precisely investigated in several operation modes where the RF phases in accelerating tubes and a prebuncher were varied. The femto-second streak camera was utilized to measure the bunch structure by one shot via Cherenkov radiation emitted by the electrons in the bunch. Next, an experiment for magnetic pulse compression of the original single bunch was carried out. Pulse shapes of the compressed bunchs for different energy modulation were also obtained by measuring Cherenkov radiation by one shot using the femto-second streak camera. Prior to the experiment, numerical tracking analysis to determine operating parameters for the magnetic pulse compression was also done. Measured pulse widths were compared with calculated ones. Finally, a 2 ps (full width at half maximum; FWHM) single bunch with an electric charge of 0.3 nC could be generated by the magnetic pulse compression. ((orig.))

  6. Longitudinal single-bunch instabilities

    International Nuclear Information System (INIS)

    Migliorati, M.; Palumbo, L.; Rome Univ. La Sapienza, Rome

    2001-02-01

    After introducing the concepts of longitudinal wakefield and coupling impedance, it is reviewed the theory of longitudinal single-bunch collective effects in storage rings. From the Fokker-Planck equation it is first derived the stationary solution describing the natural single-bunch regime, and then treat the problem of microwave instability, showing the different approaches used for estimating the threshold current. The lecture is ended with the semi-empirical laws that allow everyone to obtain the single-bunch behaviour above threshold, and with a description of the simulation codes that are now reliable tools for investigating all these effects

  7. Overview of bunch length measurements

    International Nuclear Information System (INIS)

    Lumpkin, A. H.

    1999-01-01

    An overview of particle and photon beam bunch length measurements is presented in the context of free-electron laser (FEL) challenges. Particle-beam peak current is a critical factor in obtaining adequate FEL gain for both oscillators and self-amplified spontaneous emission (SASE) devices. Since measurement of charge is a standard measurement, the bunch length becomes the key issue for ultrashort bunches. Both time-domain and frequency-domain techniques are presented in the context of using electromagnetic radiation over eight orders of magnitude in wavelength. In addition, the measurement of microbunching in a micropulse is addressed

  8. Spine formation pattern of adult-born neurons is differentially modulated by the induction timing and location of hippocampal plasticity.

    Directory of Open Access Journals (Sweden)

    Noriaki Ohkawa

    Full Text Available In the adult hippocampus dentate gyrus (DG, newly born neurons are functionally integrated into existing circuits and play important roles in hippocampus-dependent memory. However, it remains unclear how neural plasticity regulates the integration pattern of new neurons into preexisting circuits. Because dendritic spines are major postsynaptic sites for excitatory inputs, spines of new neurons were visualized by retrovirus-mediated labeling to evaluate integration. Long-term potentiation (LTP was induced at 12, 16, or 21 days postinfection (dpi, at which time new neurons have no, few, or many spines, respectively. The spine expression patterns were investigated at one or two weeks after LTP induction. Induction at 12 dpi increased later spinogenesis, although the new neurons at 12 dpi didn't respond to the stimulus for LTP induction. Induction at 21 dpi transiently mediated spine enlargement. Surprisingly, LTP induction at 16 dpi reduced the spine density of new neurons. All LTP-mediated changes specifically appeared within the LTP-induced layer. Therefore, neural plasticity differentially regulates the integration of new neurons into the activated circuit, dependent on their developmental stage. Consequently, new neurons at different developmental stages may play distinct roles in processing the acquired information by modulating the connectivity of activated circuits via their integration.

  9. Multi-bunch feedback systems

    CERN Document Server

    Lonza, M

    2008-01-01

    Coupled-bunch instabilities excited by the interaction of the particle beam with its surroundings can seriously limit the performance of circular particle accelerators. These instabilities can be cured by the use of active feedback systems based on sensors capable of detecting the unwanted beam motion and actuators that apply the feedback correction to the beam. The advances in electronic technology now allow the implementation of feedback loops using programmable digital systems. Besides important advantages in terms of flexibility and reproducibility, digital systems open the way to the use of novel diagnostic tools and additional features. The lecture will first introduce coupled-bunch instabilities analysing the equation of motion of charged particles and the different modes of oscillation of a multi-bunch beam, showing how they can be observed and measured. Different types of feedbacks systems will then be presented as examples of real implementations that belong to the history of multi-bunch feedback sy...

  10. Multi-bunch Feedback Systems

    CERN Document Server

    Lonza, M.

    2014-12-19

    Coupled-bunch instabilities excited by the interaction of the particle beam with its surroundings can seriously limit the performance of circular particle accelerators. These instabilities can be cured by the use of active feedback systems based on sensors capable of detecting the unwanted beam motion and actuators that apply the feedback correction to the beam. Advances in electronic technology now allow the implementation of feedback loops using programmable digital systems. Besides important advantages in terms of flexibility and reproducibility, digital systems open the way to the use of novel diagnostic tools and additional features. We first introduce coupled-bunch instabilities, analysing the equation of motion of charged particles and the different modes of oscillation of a multi-bunch beam, showing how they can be observed and measured. Different types of feedback systems will then be presented as examples of real implementations that belong to the history of multi-bunch feedback systems. The main co...

  11. Coasting beam theory applied to bunches

    International Nuclear Information System (INIS)

    Hereward, H.

    1975-01-01

    It is plausible to apply coasting beam criteria to bunches if one has short wavelength disturbances of the bunch and short memory wake fields, where short means short compared with a bunch length, for then one can argue that a piece of the bunch near the middle does not even know that the bunch has ends. Some other conditions probably required to validate this approach are discussed. The local Keil-Schnell criterion is derived from the local dispersion integral

  12. Resistive theory of bunch lengthening

    International Nuclear Information System (INIS)

    Month, M.; Messerschmid, E.

    1977-01-01

    A new theory of bunch lengthening in electron storage rings is proposed. The equilibrium bunch length is that length which stabilizes the bunch against the onset of ''fast'' resistive instability, caused by the combination of many high frequency resonators such as vacuum flanges. The heat dissipated in these impedance sources follows immediately from the bunch length. It is found that the anomalous bunch length is determined by a scaling parameter g = (hVcos phi/sub s/)/I. Data taken in SPEAR I and II, data in which g extends in value by more than three orders of magnitude, can be fit with an appropriate choice of high frequency, large width coupling impedance. The impedance functions for SPEAR I and II are taken to be the same, a reflection of the fact that the high frequency sources are chamber discontinuities rather than structures connected with the rf systems. A parameter search leads to an impedance characterized by a central frequency approximately 5 GHz, a width (FWHM) approximately 1.8 GHz and a peak impedance approximately 0.2 M OMEGA. The expected and observed higher mode resistance (i.e., heat dissipated) for SPEAR are compared and found to be in agreement. Predictions are given for PEP and PETRA

  13. Self-bunching electron guns

    CERN Document Server

    Mako, F; Weilhammer, Peter

    1999-01-01

    We report on three electron gun projects that are aimed at power tube and injector applications. The purpose of the work is to develop robust electron guns which produce self-bunched, high-current-density beams. We have demonstrated cold emission, long life, and tolerance to contamination. The cold emission process is based on secondary electron emission. FMT has studied this resonant bunching process which gives rise to high current densities (0.01-5 kA/cm/sup 2/), high charge bunches (up to 100 nC/bunch), and short pulses (1-100 ps) for frequencies from 1 to 12 GHz. The beam pulse width is nominally ~5% of the RF period. The first project is the L-Band Micro-Pulse Gun (MPG). Measurements show ~40 ps long microbunches at ~20 A/cm/sup 2/ without contamination due to air exposure. Lifetime testing has been carried out for about 18 months operating at 1.25 GHz for almost 24 hours per day at a repetition rate of 300 Hz and 5 mu s-long macro- pulses. About 5.8*10/sup 13/ micro-bunches or 62,000 coulombs have pass...

  14. Observation of coherent Smith-Purcell and transition radiation driven by single bunch and micro-bunched electron beams

    Science.gov (United States)

    Liang, Yifan; Du, Yingchao; Su, Xiaolu; Wang, Dan; Yan, Lixin; Tian, Qili; Zhou, Zheng; Wang, Dong; Huang, Wenhui; Gai, Wei; Tang, Chuanxiang; Konoplev, I. V.; Zhang, H.; Doucas, G.

    2018-01-01

    Generation of coherent Smith-Purcell (cSPr) and transition/diffraction radiation using a single bunch or a pre-modulated relativistic electron beam is one of the growing research areas aiming at the development of radiation sources and beam diagnostics for accelerators. We report the results of comparative experimental studies of terahertz radiation generation by an electron bunch and micro-bunched electron beams and the spectral properties of the coherent transition and SP radiation. The properties of cSPr spectra are investigated and discussed, and excitations of the fundamental and second harmonics of cSPr and their dependence on the beam-grating separation are shown. The experimental and theoretical results are compared, and good agreement is demonstrated.

  15. A large amount synthesis of nanopowder using modulated induction thermal plasmas synchronized with intermittent feeding of raw materials

    International Nuclear Information System (INIS)

    Tanaka, Y; Tsuke, T; Guo, W; Uesugi, Y; Ishijima, T; Watanabe, S; Nakamura, K

    2012-01-01

    A large amount synthesis method for titanium dioxide (TiO 2 ) nanopowder is proposed by direct evaporation of titanium powders using Ar-O 2 pulse-modulated induction thermal plasma (PMITP). To realize a large amount synthesis of nanopowder, the PMITP method was combined with the intermittent and heavy load feeding of raw material powder, as well as the quenching gas injection. The intermittent powder feeding was synchronized with the modulation of the coil current sustaining the PMITP for complete evaporation of the injected powder. Synthesized particles by the developed method were analyzed by FE-SEM and XRD. Results indicated that the synthesized particles by the 20-kW PMITP with a heavy loading rate of 12.3 g min −1 had a similar particle size distribution with the mean diameter about 40 nm to those with light loading of 4.2 g min −1 .

  16. A Modified Multiband Hysteresis Controlled DTC of Induction Machine with 27-level asymmetrical CHB-MLI with NVC modulation

    Directory of Open Access Journals (Sweden)

    Rohith Balaji Jonnala

    2018-03-01

    Full Text Available The influence of Direct Torque Controlled Induction Motor Drive in the area of industrial application is very high; it presents foremost area of controllability of load at different states of operation. The major snags to the controller are maintaining Constant Switching Frequency and Infeasibility state. This paper concentrates on rectifying these problems with Modified Multiband Hysteresis Controller and Nearest Vector Control Modulated Asymmetrical Cascaded H-Bridge Multilevel Inverter for the better drive operation. In this case proper modification in MHC gives the optimal utilizations of each control vector to avoid the infeasibility states with a Lookup-Table and Multilevel Inverter gives more number of control voltage vectors with constant switching frequency for flexible operation of drive with low disturbances. Direct Torque Control equipped with these two modules achieves better operating conditions with low Torque ripples, low distorted flux and speed with different loads, and all other satisfactory load operating parameters.

  17. Measurement of electron beam bunch phase length by rectangular cavities

    International Nuclear Information System (INIS)

    Afanas'ev, V.D.; Rudychev, V.G.; Ushakov, V.I.

    1976-01-01

    An analysis of a phase length of electron bunches with the help of crossed rectangular resonators with the Hsub(102) oscillation type has been made. It has been shown that the electron coordinates after the duplex resonator are described by an ellipse equation for a non-modulated beam. An influence of the initial energy spread upon the electron motion has been studied. It has been ascertained that energy modulation of the electron beam results in displacement of each electron with respect to the ellipse which is proportional to modulation energy, i.e. an error in determination of the phase length of an electron bunch is proportional to the beam energy spread. Relations have been obtained which enable to find genuine values of phases of the analyzed electrons with an accuracy up to linear multipliers

  18. Early cytokine modulation after the rapid induction phase of sublingual immunotherapy with mite monomeric allergoids.

    Science.gov (United States)

    Di Gioacchino, M; Perrone, A; Petrarca, C; Di Claudio, F; Mistrello, G; Falagiani, P; Dadorante, V; Verna, N; Braga, M; Ballone, E; Cavallucci, E

    2008-01-01

    The influence of different treatment schedules of sublingual immunotherapy (SLIT) in activating IL-10-producing T-cells, crucial in inducing allergen-specific tolerance, is not completely understood. The present work was designed to evaluate allergen driven interleukin release by mononuclear cells in the early phase of SLIT, after application of different induction schemes. Twenty mite-allergic patients were enrolled, 10 (group A) treated with a traditional 98 day induction scheme and 10 (group B) with a 16 day scheme with monomeric allergoid vaccine. At the end of the induction phase, the cumulative doses taken by group A and group B patients were equivalent to 50.5 and 50.3 microg of mite group 1 allergens, respectively. The release of Th1-, Th2- and Treg-related interleukins was assessed in culture supernatants of 5 microg/ml Der-p1-stimulated mononuclear cells, isolated before and after the induction phases. No relevant treatment-related side effects were observed. Interleukin release was similar in the two groups at the enrolment. Non-stimulated and Der p 1 stimulated release of studied cytokines was similar in the two groups at enrolment. Der p 1 stimulation significantly increased IL-10 release (pallergoids are utilized.

  19. Transverse and longitudinal coupled bunch instabilities in trains of closely spaced bunches

    International Nuclear Information System (INIS)

    Thompson, K.A.; Ruth, R.D.

    1989-03-01

    Damping rings for the next generation of linear collider may need to contain several bunch trains within which the bunches are quire closely spaced (1 or 2 RF wavelengths). Methods are presented for studying the transverse and longitudinal coupled bunch instabilities, applicable to this problem and to other cases in which the placement of the bunches is not necessarily symmetric. 5 refs., 1 fig

  20. Bunched beam longitudinal stability

    International Nuclear Information System (INIS)

    Baartman, R.

    1991-05-01

    Instabilities driven by narrow-band impedances can be stabilized by Landau damping arising from the synchrotron frequency spread due to the nonlinearity of the rf wave-form. We calculate stability diagrams for various phase space distributions. We find that distributions without tails are unstable in the 'negative mass' regime (inductive impedance below transition or capacitive impedance above transition). We also find that longitudinal instability thresholds of the (usually neglected) higher order radial modes are lower than expected. For example, the next to lowest dipole mode has a lower threshold than the lowest sextupole mode even though the latter has the larger growth rate in the absence of Landau damping. (Author) 5 refs., 5 figs

  1. Bunch coalescing and bunch rotation in the Fermilab Main Ring: Operational experience and comparison with simulations

    International Nuclear Information System (INIS)

    Martin, P.S.; Wildman, D.W.

    1988-01-01

    The Fermilab Tevatron I proton-antiproton collider project requires that the Fermilab Main Ring produce intense bunches of protons and antiprotons for injection into the Tevatron. The process of coalescing a small number of harmonic number h=1113 bunches into a single bunch by bunch-rotating in a lower harmonic rf system is described.The Main Ring is also required to extract onto the antiproton production target bunches with as narrow a time spread as possible. This operation is also discussed. The operation of the bunch coalescing and bunch rotation are compared with simulations using the computer program ESME. 2 refs., 8 figs

  2. Theoretical models for describing longitudinal bunch compression in the neutralized drift compression experiment

    Directory of Open Access Journals (Sweden)

    Adam B. Sefkow

    2006-09-01

    Full Text Available Heavy ion drivers for warm dense matter and heavy ion fusion applications use intense charge bunches which must undergo transverse and longitudinal compression in order to meet the requisite high current densities and short pulse durations desired at the target. The neutralized drift compression experiment (NDCX at the Lawrence Berkeley National Laboratory is used to study the longitudinal neutralized drift compression of a space-charge-dominated ion beam, which occurs due to an imposed longitudinal velocity tilt and subsequent neutralization of the beam’s space charge by background plasma. Reduced theoretical models have been used in order to describe the realistic propagation of an intense charge bunch through the NDCX device. A warm-fluid model is presented as a tractable computational tool for investigating the nonideal effects associated with the experimental acceleration gap geometry and voltage waveform of the induction module, which acts as a means to pulse shape both the velocity and line density profiles. Self-similar drift compression solutions can be realized in order to transversely focus the entire charge bunch to the same focal plane in upcoming simultaneous transverse and longitudinal focusing experiments. A kinetic formalism based on the Vlasov equation has been employed in order to show that the peaks in the experimental current profiles are a result of the fact that only the central portion of the beam contributes effectively to the main compressed pulse. Significant portions of the charge bunch reside in the nonlinearly compressing part of the ion beam because of deviations between the experimental and ideal velocity tilts. Those regions form a pedestal of current around the central peak, thereby decreasing the amount of achievable longitudinal compression and increasing the pulse durations achieved at the focal plane. A hybrid fluid-Vlasov model which retains the advantages of both the fluid and kinetic approaches has been

  3. Priming, induction and modulation of plant defence responses by bacterial lipopolysaccharides

    DEFF Research Database (Denmark)

    Newman, Mari-Anne; Dow, J. Maxwell; Molinaro, Antonio

    2007-01-01

    Bacterial lipopolysaccharides (LPSs) have multiple roles in plant-microbe interactions. LPS contributes to the low permeability of the outer membrane, which acts as a barrier to protect bacteria from plant-derived antimicrobial substances. Conversely, perception of LPS by plant cells can lead...... to the triggering of defence responses or to the priming of the plant to respond more rapidly and/or to a greater degree to subsequent pathogen challenge. LPS from symbiotic bacteria can have quite different effects on plants to those of pathogens. Some details are emerging of the structures within LPS...... that are responsible for induction of these different plant responses. The lipid A moiety is not solely responsible for all of the effects of LPS in plants; core oligosaccharide and O-antigen components can elicit specific responses. Here, we review the effects of LPS in induction of defence-related responses...

  4. Acceleration of a high-current single bunch in a linear accelerator

    International Nuclear Information System (INIS)

    Takeda, Seishi

    1984-01-01

    Some problems associated with the feasibility of an electron-positron linear collider with colliding energy of about 1x1 TeV are discussed. The first problem is related to the generation of high-current single bunch. A quasi-relativistic electron beam from an electron gun is injected into one bucket of the accelerating fields, in opposition to the longitudinal defocusing due to the space-charge effect. For generating a high-current single bunch, the beam bunching by means of the velocity modulation with a subharmonic prebuncher (SHPB) is indispensable. Three existing second generation single bunch electron linear accelerators (SLC, ANL and ISLR-Osaka Univ.) are briefly described. The results of the simulation of subharmonic-bunching is also reported. The second problem is associated with the physics of accelerating high-current single bunch. The longitudinal and transverse wake fields generated by a bunch-cavity interaction and the energy spread of the single bunch are analyzed and discussed. (Aoki, K.)

  5. Multi-bunch Feedback Systems

    International Nuclear Information System (INIS)

    Lonza, M; Schmickler, H

    2014-01-01

    Coupled-bunch instabilities excited by the interaction of the particle beam with its surroundings can seriously limit the performance of circular particle accelerators. These instabilities can be cured by the use of active feedback systems based on sensors capable of detecting the unwanted beam motion and actuators that apply the feedback correction to the beam. Advances in electronic technology now allow the implementation of feedback loops using programmable digital systems. Besides important advantages in terms of flexibility and reproducibility, digital systems open the way to the use of novel diagnostic tools and additional features. We first introduce coupled-bunch instabilities, analysing the equation of motion of charged particles and the different modes of oscillation of a multi-bunch beam, showing how they can be observed and measured. Different types of feedback systems will then be presented as examples of real implementations that belong to the history of multi-bunch feedback systems. The main components of a feedback system and the related issues will also be analysed. Finally, we shall focus on digital feedback systems, their characteristics, and features, as well as on how they can be concretely exploited for both the optimization of feedback performance and for beam dynamics studies

  6. Self-bunching electron guns

    Science.gov (United States)

    Mako, Frederick M.; Len, L. K.

    1999-05-01

    We report on three electron gun projects that are aimed at power tube and injector applications. The purpose of the work is to develop robust electron guns which produce self-bunched, high-current-density beams. We have demonstrated, in a microwave cavity, self-bunching, cold electron emission, long life, and tolerance to contamination. The cold process is based on secondary electron emission. FMT has studied using simulation codes the resonant bunching process which gives rise to high current densities (0.01-5 kA/cm2), high charge bunches (up to 500 nC/bunch), and short pulses (1-100 ps) for frequencies from 1 to 12 GHz. The beam pulse width is nominally ˜5% of the rf period. The first project is the L-Band Micro-Pulse Gun (MPG). Measurements show ˜40 ps long micro-bunches at ˜20 A/cm2 without contamination due to air exposure. Lifetime testing has been carried out for about 18 months operating at 1.25 GHz for almost 24 hours per day at a repetition rate of 300 Hz and 5 μs-long macro-pulses. Approximately 5.8×1013 micro-bunches or 62,000 coulombs have passed through this gun and it is still working fine. The second project, the S-Band MPG, is now operational. It is functioning at a frequency of 2.85 GHz, a repetition rate of 30 Hz, with a 2 μs-long macro-pulse. It produces about 45 A in the macro-pulse. The third project is a 34.2 GHz frequency-multiplied source driven by an X-Band MPG. A point design was performed at an rf output power of 150 MW at 34.2 GHz. The resulting system efficiency is 53% and the gain is 60 dB. The system efficiency includes the input cavity efficiency, input driver efficiency (a 50 MW klystron at 11.4 GHz), output cavity efficiency, and the post-acceleration efficiency.

  7. Turn-by-Turn and Bunch-by-Bunch Transverse Profiles of a Single Bunch in a Full Ring

    International Nuclear Information System (INIS)

    Kraus, R.; Fisher, A.S.

    2005-01-01

    The apparatus described in this paper can image the evolution of the transverse profile of a single bunch, isolated from a full PEP-II ring of 1500 bunches. Using this apparatus there are two methods of single bunch imaging; bunch-by-bunch beam profiling can image every bunch in the ring a single bunch at a time with the images of sequential bunches being in order, allowing one to see variations in beam size along a train. Turn-by-turn beam profiling images a single bunch on each successive turn it makes around the ring. This method will be useful in determining the effect that an injected bunch has on a stable bunch as the oscillations of the injected bunch damp out. Turn-by-turn imaging of the synchrotron light uses a system of lenses and mirrors to image many turns of both the major and minor axis of a single bunch across the photocathode of a gateable camera. The bunch-by-bunch method is simpler: because of a focusing mirror used in porting the light from the ring, the synchrotron light from the orbiting electrons becomes an image at a certain distance from the mirror; and since the camera does not use a lens, the photocathode is set exactly at this image distance. Bunch-by-bunch profiling has shown that in the Low Energy Ring (LER) horizontal bunch size decreases along a train. Turn-by-turn profiling has been able to image 100 turns of a single bunch on one exposure of the camera. The turn-by-turn setup has also been able to image 50 turns of the minor axis showing part of the damping process of an oscillating injected charge during a LER fill. The goal is to image the damping of oscillations of injected charge for 100 turns of both the major and minor axis throughout the damping process during trickle injection. With some changes to the apparatus this goal is within reach and will make turn-by-turn imaging a very useful tool in beam diagnostics

  8. Femtosecond electron bunches, source and characterization

    International Nuclear Information System (INIS)

    Thongbai, C.; Kusoljariyakul, K.; Rimjaem, S.; Rhodes, M.W.; Saisut, J.; Thamboon, P.; Wichaisirimongkol, P.; Vilaithong, T.

    2008-01-01

    A femtosecond electron source has been developed at the Fast Neutron Research Facility (FNRF), Chiang Mai University, Thailand. So far, it has produced electron bunches as short as σ z ∼180 fs with (1-6)x10 8 electrons per microbunch. The system consists of an RF-gun with a thermionic cathode, an alpha-magnet as a magnetic bunch compressor, and a linear accelerator as a post acceleration section. Coherent transition radiation emitted at wavelengths equal to and longer than the bunch length is used in a Michelson interferometer to determine the bunch length by autocorrelation technique. The experimental setup and results of the bunch length measurement are described

  9. MEASURING TEMPORAL PHOTON BUNCHING IN BLACKBODY RADIATION

    Energy Technology Data Exchange (ETDEWEB)

    Tan, P. K.; Poh, H. S.; Kurtsiefer, C. [Center for Quantum Technologies, 3 Science Drive 2, 117543 (Singapore); Yeo, G. H.; Chan, A. H., E-mail: pengkian@physics.org, E-mail: phyck@nus.edu.sg [Department of Physics, National University of Singapore, 2 Science Drive 3, 117551 (Singapore)

    2014-07-01

    Light from thermal blackbody radiators such as stars exhibits photon bunching behavior at sufficiently short timescales. However, with available detector bandwidths, this bunching signal is difficult to observe directly. We present an experimental technique to increase the photon bunching signal in blackbody radiation via spectral filtering of the light source. Our measurements reveal strong temporal photon bunching from blackbody radiation, including the Sun. This technique allows for an absolute measurement of the photon bunching signature g {sup (2)}(0), and thereby a direct statement on the statistical nature of a light source. Such filtering techniques may help revive the interest in intensity interferometry as a tool in astronomy.

  10. Measuring the electron bunch timing with femtosecond resolution at FLASH

    International Nuclear Information System (INIS)

    Bock, Marie Kristin

    2013-03-01

    Bunch arrival time monitors (BAMs) are an integral part of the laser-based synchronisation system which is being developed at the Free Electron Laser in Hamburg (FLASH).The operation principle comprises the measurement of the electron bunch arrival time relative to the optical timing reference, which is provided by actively length-stabilised fibre-links of the synchronisation system. The monitors are foreseen to be used as a standard diagnostic tool, not only for FLASH but also for the future European X-Ray Free-Electron Laser (European XFEL). The present bunch arrival time monitors have evolved from proof-of-principle experiments to beneficial diagnostic devices, which are almost permanently available during standard machine operation. This achievement has been a major objective of this thesis. The developments went in parallel to improvements in the reliable and low-maintenance operation of the optical synchronisation system. The key topics of this thesis comprised the characterisation and optimisation of the opto-mechanical front-ends of both, the fibre-links and the BAMs. The extent of applications involving the bunch arrival time information has been enlarged, providing automated measurements for properties of the RF acceleration modules, for instance, the RF on-crest phase determination and the measurement of energy fluctuations. Furthermore, two of the currently installed BAMs are implemented in an active phase and gradient stabilisation of specific modules in order to minimise the arrival time jitter of the electron bunches at the location of the FEL undulators, which is crucial for a high timing resolution of pump-probe experiments.

  11. Measuring the electron bunch timing with femtosecond resolution at FLASH

    Energy Technology Data Exchange (ETDEWEB)

    Bock, Marie Kristin

    2013-03-15

    Bunch arrival time monitors (BAMs) are an integral part of the laser-based synchronisation system which is being developed at the Free Electron Laser in Hamburg (FLASH).The operation principle comprises the measurement of the electron bunch arrival time relative to the optical timing reference, which is provided by actively length-stabilised fibre-links of the synchronisation system. The monitors are foreseen to be used as a standard diagnostic tool, not only for FLASH but also for the future European X-Ray Free-Electron Laser (European XFEL). The present bunch arrival time monitors have evolved from proof-of-principle experiments to beneficial diagnostic devices, which are almost permanently available during standard machine operation. This achievement has been a major objective of this thesis. The developments went in parallel to improvements in the reliable and low-maintenance operation of the optical synchronisation system. The key topics of this thesis comprised the characterisation and optimisation of the opto-mechanical front-ends of both, the fibre-links and the BAMs. The extent of applications involving the bunch arrival time information has been enlarged, providing automated measurements for properties of the RF acceleration modules, for instance, the RF on-crest phase determination and the measurement of energy fluctuations. Furthermore, two of the currently installed BAMs are implemented in an active phase and gradient stabilisation of specific modules in order to minimise the arrival time jitter of the electron bunches at the location of the FEL undulators, which is crucial for a high timing resolution of pump-probe experiments.

  12. Cyclooxygenase-2 induction in macrophages is modulated by docosahexaenoic acid via interactions with free fatty acid receptor 4 (FFA4).

    Science.gov (United States)

    Li, Xinzhi; Yu, Ying; Funk, Colin D

    2013-12-01

    Cyclooxygenase-2 (COX-2)-derived prostaglandins are implicated in numerous inflammatory disorders. The purpose of these studies was to examine previously unexplored interactions between COX-2 induction and docosahexaenoic acid (DHA) via the free fatty acid receptor 4 (FFA4) signaling pathway in murine RAW 264.7 cells and peritoneal macrophages challenged with lipopolysaccharide (LPS). DHA dose (IC50=18 μM)- and time-dependently reduced COX-2 expression, without affecting COX-1. DHA (25 μM for 24 h) decreased LPS-induced prostaglandin E2 (PGE2) synthesis by 81%, primarily through reducing COX-2 (60%), as well as down-regulating microsomal prostaglandin E synthase-1 (46%), but independently of peroxisome proliferator-activated receptors. FFA4 knockdown abrogated DHA effects on COX-2 induction, PGE2 production, and interleukin 6 (IL-6) gene expression. In the presence of inhibitors of eicosanoid metabolism via COX-2, 12/15-lipoxygenase and CYP450s (rofecoxib (1 μM), PD146176 (2 μM), or MS-PPOH (20 μM)), DHA was still effective in attenuating COX-2 induction. Moreover, Toll-like receptor 4 signaling via Akt/JNK phosphorylation and p65 nuclear translocation was repressed by DHA-activated FFA4 coupling with β-arrestin 2, which was reversed by FFA4 knockdown. These data support DHA modulation of COX-2 expression and activity, in part, via FFA4, which provides a new mechanistic explanation for some of the anti-inflammatory effects of DHA.

  13. Improvement of bunch-by-bunch beam current detection system in Hefei light source

    International Nuclear Information System (INIS)

    Zheng Kai; Wang Junhua; Liu Zuping; Li Weimin; Zhou Zeran; Yang Yongliang; Huang Longjun; Chen Yuanbo

    2006-01-01

    Bunch-by-bunch beam current detection system is an important facility in the multibunch storage ring. In this paper, the established bunch-by-bunch beam current detection systems for the accelerator such as Cornell, SLAC and KEKB were compared and studied. The design of the bunch-by-bunch beam current detection system for HLS, which was based on the bunch-by-bunch tracing measurement system in HLS was given. Both demodulation by sine wave and square were applied in this paper, the deviation of the detect system was determined by the longitudinal oscillation. Compared the data acquired from ADC with the data from DCCT, the ADC data was scaled by the bunch current. The standard deviations of linear fit were about 1%, and the standard deviations of polynomial fit were less than 0.5% in both sine wave and square wave demodulation. Some analysis of the measurement results also had been shown in this paper. (authors)

  14. Quantum beamstrahlung from gaussian bunches

    International Nuclear Information System (INIS)

    Chen, P.

    1987-08-01

    The method of Baier and Katkov is applied to calculate the correction terms to the Sokolov-Ternov radiation formula due to the variation of the magnetic field strength along the trajectory of a radiating particle. We carry the calculation up to the second order in the power expansion of B tau/B, where tau is the formation time of radiation. The expression is then used to estimate the quantum beamstrahlung average energy loss from e + e - bunches with gaussian distribution in bunch currents. We show that the effect of the field variation is to reduce the average energy loss from previous calculations based on the Sokolov-Ternov formula or its equivalent. Due to the limitation of our method, only an upper bound of the reduction is obtained. 18 refs

  15. Multi-bunch Feedback Systems

    OpenAIRE

    Lonza, M.; Schmickler, H.

    2016-01-01

    Coupled-bunch instabilities excited by the interaction of the particle beam with its surroundings can seriously limit the performance of circular particle accelerators. These instabilities can be cured by the use of active feedback systems based on sensors capable of detecting the unwanted beam motion and actuators that apply the feedback correction to the beam. Advances in electronic technology now allow the implementation of feedback loops using programmable digital systems. Besides importa...

  16. Influence of coil current modulation on polycrystalline diamond film deposition by irradiation of Ar/CH4/H2 inductively coupled thermal plasmas

    Science.gov (United States)

    Betsuin, Toshiki; Tanaka, Yasunori; Arai, T.; Uesugi, Y.; Ishijima, T.

    2018-03-01

    This paper describes the application of an Ar/CH4/H2 inductively coupled thermal plasma with and without coil current modulation to synthesise diamond films. Induction thermal plasma with coil current modulation is referred to as modulated induction thermal plasma (M-ITP), while that without modulation is referred to as non-modulated ITP (NM-ITP). First, spectroscopic observations of NM-ITP and M-ITP with different modulation waveforms were made to estimate the composition in flux from the thermal plasma by measuring the time evolution in the spectral intensity from the species. Secondly, we studied polycrystalline diamond film deposition tests on a Si substrate, and we studied monocrystalline diamond film growth tests using the irradiation of NM-ITP and M-ITP. From these tests, diamond nucleation effects by M-ITP were found. Finally, following the irradiation results, we attempted to use a time-series irradiation of M-ITP and NM-ITP for polycrystalline diamond film deposition on a Si substrate. The results indicated that numerous larger diamond particles were deposited with a high population density on the Si substrate by time-series irradiation.

  17. GPER1-mediated IGFBP-1 induction modulates IGF-1-dependent signaling in tamoxifen-treated breast cancer cells.

    Science.gov (United States)

    Vaziri-Gohar, Ali; Houston, Kevin D

    2016-02-15

    Tamoxifen, a selective estrogen receptor modulator, is a commonly prescribed adjuvant therapy for estrogen receptor-α (ERα)-positive breast cancer patients. To determine if extracellular factors contribute to the modulation of IGF-1 signaling after tamoxifen treatment, MCF-7 cells were treated with IGF-1 in conditioned medium (CM) obtained from 4-OHT-treated MCF-7 cells and the accumulation of phospho-Akt (S473) was measured. CM inhibited IGF-1-dependent cell signaling and suggesting the involvement of extracellular factors (ie. IGFBPs). A significant increase in IGFBP-1 mRNA and extracellular IGFBP-1 protein was observed in 4-OHT-treated MCF-7 cells. Knockdown experiments demonstrated that both GPER1 and CREB mediate IGFBP-1 induction. Furthermore, experiments showed that 4-OHT-dependent IGFBP-1 transcription is downstream of GPER1-activation in breast cancer cells. Additionally, neutralization and knockdown experiments demonstrated a role for IGFBP-1 in the observed inhibition of IGF-1 signaling. These results suggested that 4-OHT inhibits IGF-1 signaling via GPER1 and CREB mediated extracellular IGFBP-1 accumulation in breast cancer cells. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  18. Modulating effects of thyroid state on the induction of biotransformation enzymes byu 2,3,7,8-tetrachlorodibenzo-p-dioxin.

    NARCIS (Netherlands)

    Schuur, A.G.; Tacken, P.J.; Visser, T.J.; Brouwer, A.

    1998-01-01

    In this study we investigated to what extent the induction of detoxification enzymes by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is modulated by concomitant TCDD-induced changes in thyroid state. Euthyroid (Eu) male Sprague-Dawley rats, surgically thyroidectomized (Tx) rats and Tx rats receiving

  19. Global (volume-averaged) model of inductively coupled chlorine plasma : influence of Cl wall recombination and external heating on continuous and pulse-modulated plasmas

    NARCIS (Netherlands)

    Kemaneci, E.H.; Carbone, E.A.D.; Booth, J.P.; Graef, W.A.A.D.; Dijk, van J.; Kroesen, G.M.W.

    An inductively coupled radio-frequency plasma in chlorine is investigated via a global (volume-averaged) model, both in continuous and square wave modulated power input modes. After the power is switched off (in a pulsed mode) an ion–ion plasma appears. In order to model this phenomenon, a novel

  20. Enabling Junction Temperature Estimation via Collector-Side Thermo-Sensitive Electrical Parameters through Emitter Stray Inductance in High-Power IGBT Modules

    DEFF Research Database (Denmark)

    Luo, Haoze; Li, Wuhua; Iannuzzo, Francesco

    2018-01-01

    This paper proposes the adoption of the inherent emitter stray inductance LeE in high-power insulated gate bipolar transistor (IGBT) modules as a new dynamic thermo-sensitive electrical parameter (d-TSEP). Furthermore, a family of 14 derived dynamic TSEP candidates has been extracted and classified...

  1. High energy, low inductance, high current fiberglass energy storage capacitor for the Atlas Machine Marx modules

    CERN Document Server

    Cooper, R A; Ennis, J B; Cochrane, J C; Reass, W A; Parsons, W M

    1999-01-01

    The Los Alamos National Laboratory's Atlas Marx design team envisioned a double ended plastic case 60 kV, 15 nH, 650 kA, energy storage capacitor. A design specification was established and submitted to various vendors. Maxwell Energy Products drew from its development of large fiberglass case, high voltage, low inductance "FASTCAP" capacitors manufactured for Maxwell Technologies' ACE II, ACE III and ACE IV machines. This paper discusses the LANL specification and Maxwell Energy Products' successful design, Model No. 39232, 34.1 mu F, 60 kV, 13*29*27", the only capacitor qualified by LANL for the 23 Mega Joule Atlas application. Maxwell's past experience in this type of capacitor is covered. The performance data is reviewed and the life test data compared to the original calculated design life. Challenges included Maxwell's "keep it simple " design goal which was maintained to minimize the effort required to create and manufacture a nearly 600 pound capacitor. (1 refs).

  2. Modeling two-stage bunch compression with wakefields: Macroscopic properties and microbunching instability

    Directory of Open Access Journals (Sweden)

    R. A. Bosch

    2008-09-01

    Full Text Available In a two-stage compression and acceleration system, where each stage compresses a chirped bunch in a magnetic chicane, wakefields affect high-current bunches. The longitudinal wakes affect the macroscopic energy and current profiles of the compressed bunch and cause microbunching at short wavelengths. For macroscopic wavelengths, impedance formulas and tracking simulations show that the wakefields can be dominated by the resistive impedance of coherent edge radiation. For this case, we calculate the minimum initial bunch length that can be compressed without producing an upright tail in phase space and associated current spike. Formulas are also obtained for the jitter in the bunch arrival time downstream of the compressors that results from the bunch-to-bunch variation of current, energy, and chirp. Microbunching may occur at short wavelengths where the longitudinal space-charge wakes dominate or at longer wavelengths dominated by edge radiation. We model this range of wavelengths with frequency-dependent impedance before and after each stage of compression. The growth of current and energy modulations is described by analytic gain formulas that agree with simulations.

  3. Design of BEPCII bunch current monitor system

    International Nuclear Information System (INIS)

    Zhang Lei; Ma Huizhou; Yue Junhui; Lei Ge; Cao Jianshe; Ma Li

    2008-01-01

    BEPC II is an electron-positron collider designed to run under multi-bunches and high beam current condition. The accelerator consists of an electron ring, a positron ring and a linear injector. In order to achieve the target luminosity and implement the equal bunch charge injection, the Bunch Current Monitor (BCM) system is built on BEPC II. The BCM system consists of three parts: the front-end circuit, the bunch current acquisition system and the bucket selection system. The control software of BCM is based on VxWorks and EPICS. With the help of BCM system, the bunch current in each bucket can be monitored in the Central Control Room. The BEPC II timing system can also use the bunch current database to decide which bucket needs to refill to implement 'top-off' injection. (authors)

  4. Prefrontal and parietal activity is modulated by the rule complexity of inductive reasoning and can be predicted by a cognitive model.

    Science.gov (United States)

    Jia, Xiuqin; Liang, Peipeng; Shi, Lin; Wang, Defeng; Li, Kuncheng

    2015-01-01

    In neuroimaging studies, increased task complexity can lead to increased activation in task-specific regions or to activation of additional regions. How the brain adapts to increased rule complexity during inductive reasoning remains unclear. In the current study, three types of problems were created: simple rule induction (i.e., SI, with rule complexity of 1), complex rule induction (i.e., CI, with rule complexity of 2), and perceptual control. Our findings revealed that increased activations accompany increased rule complexity in the right dorsal lateral prefrontal cortex (DLPFC) and medial posterior parietal cortex (precuneus). A cognitive model predicted both the behavioral and brain imaging results. The current findings suggest that neural activity in frontal and parietal regions is modulated by rule complexity, which may shed light on the neural mechanisms of inductive reasoning. Copyright © 2014. Published by Elsevier Ltd.

  5. Beam diagnostics based on time-domain bunch-by-bunch data

    International Nuclear Information System (INIS)

    Teytelman, D.; Fox, J.; Hindi, H.; Limborg, C.; Linscott, I.; Prabhakar, S.; Sebek, J.; Young, A.; Drago, A.; Serio, M.; Barry, W.; Stover, G.

    1998-01-01

    A bunch-by-bunch longitudinal feedback system has been used to control coupled-bunch longitudinal motion and study the behavior of the beam at ALS, SPEAR, PEP-II, and DAΦNE. Each of these machines presents unique challenges to feedback control of unstable motion and data analysis. Here we present techniques developed to adapt this feedback system to operating conditions at these accelerators. A diverse array of techniques has been developed to extract information on different aspects of beam behavior from the time-domain data captured by the feedback system. These include measurements of growth and damping rates of coupled-bunch modes, bunch-by-bunch current monitoring, measurements of bunch-by-bunch synchronous phases and longitudinal tunes, and beam noise spectra. A technique is presented which uses the longitudinal feedback system to measure transverse growth and damping rates. Techniques are illustrated with data acquired at all of the four above-mentioned machines

  6. CPEB1 modulates lipopolysaccharide-mediated iNOS induction in rat primary astrocytes

    International Nuclear Information System (INIS)

    Kim, Ki Chan; Hyun Joo, So; Shin, Chan Young

    2011-01-01

    Highlights: → Expression and phosphorylation of CPEB1 is increased by LPS stimulation in rat primary astrocytes. → JNK regulates expression and phosphorylation of CPEB1 in reactive astrocytes. → Down-regulation of CPEB1 using siRNA inhibits oxidative stress and iNOS induction by LPS stimulation. → CPEB1 may play an important role in regulating inflammatory responses in reactive astrocytes induced by LPS. -- Abstract: Upon CNS damage, astrocytes undergo a series of biological changes including increased proliferation, production of inflammatory mediators and morphological changes, in a response collectively called reactive gliosis. This process is an essential part of the brains response to injury, yet much is unknown about the molecular mechanism(s) that induce these changes. In this study, we investigated the role of cytoplasmic polyadenylation element binding protein 1 (CPEB1) in the regulation of inflammatory responses in a model of reactive gliosis, lipopolysaccharide-stimulated astrocytes. CPEB1 is an mRNA-binding protein recently shown to be expressed in astrocytes that may play a role in astrocytes migration. After LPS stimulation, the expression and phosphorylation of CPEB1 was increased in rat primary astrocytes in a JNK-dependent process. siRNA-induced knockdown of CPEB1 expression inhibited the LPS-induced up-regulation of iNOS as well as NO and ROS production, a hallmark of immunological activation of astrocytes. The results from the study suggest that CPEB1 is actively involved in the regulation of inflammatory responses in astrocytes, which might provide new insights into the regulatory mechanism after brain injury.

  7. Bunch compression at the Stanford Linear Collider

    International Nuclear Information System (INIS)

    Holtzapple, R.L.; Decker, F.J.; Simopoulos, C.

    1995-08-01

    The production and measurement of short electron and positron bunches in the Stanford Linear Collider (SLC) will be presented in this paper. The bunches are compressed in a transport line between the damping rings and the linac. The electron and positron bunch distributions in the SLC linac have been measured using a Hamamatsu, model N3373-02, 500-femtosecond streak camera. The distributions were measured at the end of the SLC linac versus the bunch compressor RF voltage. The measurements are compared with simulations

  8. Certain features of FELs with short bunches

    International Nuclear Information System (INIS)

    Lebedev, A.N.

    2006-01-01

    The report is devoted to physics of free electron lasers operating in the short-wave domain where the bunch length could be less than the undulator length in the proper frame. Then the current component of the signal is locked within the bunch as in a cavity, while the electromagnetic component propagates freely. In contrast with gyrotrons where this regime can be of interest only for wavelengths comparable with the bunch length, we consider short waves in a bunch of arbitrary profile. Both amplification of an external harmonic signal and SASE regime, i.e. selective amplification of proper noises, are investigated

  9. Temporal characterization of ultrashort linearly chirped electron bunches generated from a laser wakefield accelerator

    Directory of Open Access Journals (Sweden)

    C. J. Zhang

    2016-06-01

    Full Text Available A new method for diagnosing the temporal characteristics of ultrashort electron bunches with linear energy chirp generated from a laser wakefield accelerator is described. When the ionization-injected bunch interacts with the back of the drive laser, it is deflected and stretched along the direction of the electric field of the laser. Upon exiting the plasma, if the bunch goes through a narrow slit in front of the dipole magnet that disperses the electrons in the plane of the laser polarization, it can form a series of bunchlets that have different energies but are separated by half a laser wavelength. Since only the electrons that are undeflected by the laser go through the slit, the energy spectrum of the bunch is modulated. By analyzing the modulated energy spectrum, the shots where the bunch has a linear energy chirp can be recognized. Consequently, the energy chirp and beam current profile of those bunches can be reconstructed. This method is demonstrated through particle-in-cell simulations and experiment.

  10. Measurement of Sub-Picosecond Electron Bunches via Electro-Optic Sampling of Coherent Transition Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Maxwell, Timothy John [Northern Illinois U.

    2012-01-01

    Future collider applications as well as present high-gradient laser plasma wakefield accelerators and free-electron lasers operating with picosecond bunch durations place a higher demand on the time resolution of bunch distribution diagnostics. This demand has led to significant advancements in the field of electro-optic sampling over the past ten years. These methods allow the probing of diagnostic light such as coherent transition radiation or the bunch wakefields with sub-picosecond time resolution. We present results on the single-shot electro-optic spectral decoding of coherent transition radiation from bunches generated at the Fermilab A0 photoinjector laboratory. A longitudinal double-pulse modulation of the electron beam is also realized by transverse beam masking followed by a transverse-to-longitudinal phase-space exchange beamline. Live profile tuning is demonstrated by upstream beam focusing in conjunction with downstream monitoring of single-shot electro-optic spectral decoding of the coherent transition radiation.

  11. Method for the determination of the three-dimensional structure of ultrashort relativistic electron bunches

    Energy Technology Data Exchange (ETDEWEB)

    Geloni, Gianluca; Ilinski, Petr; Saldin, Evgeni; Schneidmiller, Evgeni; Yurkov, Mikhail

    2009-05-15

    We describe a novel technique to characterize ultrashort electron bunches in Xray Free-Electron Lasers. Namely, we propose to use coherent Optical Transition Radiation to measure three-dimensional (3D) electron density distributions. Our method relies on the combination of two known diagnostics setups, an Optical Replica Synthesizer (ORS) and an Optical Transition Radiation (OTR) imager. Electron bunches are modulated at optical wavelengths in the ORS setup.When these electron bunches pass through a metal foil target, coherent radiation pulses of tens MW power are generated. It is thereafter possible to exploit advantages of coherent imaging techniques, such as direct imaging, diffractive imaging, Fourier holography and their combinations. The proposed method opens up the possibility of real-time, wavelength-limited, single-shot 3D imaging of an ultrashort electron bunch. (orig.)

  12. Insights into Host Cell Modulation and Induction of New Cells by the Corn Smut Ustilago maydis

    Directory of Open Access Journals (Sweden)

    Amey Redkar

    2017-05-01

    Full Text Available Many filamentous fungal pathogens induce drastic modulation of host cells causing abnormal infectious structures such as galls, or tumors that arise as a result of re-programming in the original developmental cell fate of a colonized host cell. Developmental consequences occur predominantly with biotrophic phytopathogens. This suggests that these host structures result as an outcome of efficient defense suppression and intimate fungal–host interaction to suit the pathogen’s needs for completion of its infection cycle. This mini-review mainly summarizes host cell re-programming that occurs in the Ustilago maydis – maize interaction, in which the pathogen deploys cell-type specific effector proteins with varying activities. The fungus senses the physiological status and identity of colonized host cells and re-directs the endogenous developmental program of its host. The disturbance of host cell physiology and cell fate leads to novel cell shapes, increased cell size, and/or the number of host cells. We particularly highlight the strategies of U. maydis to induce physiologically varied host organs to form the characteristic tumors in both vegetative and floral parts of maize.

  13. TRANSVERSE MODES FOR FLAT INTER-BUNCH WAKES*

    CERN Document Server

    Burov, A

    2013-01-01

    If inter-bunch wake fields are flat, i.e. their variations over a bunch length can be neglected, all coherent modes have the same coupled-bunch structure, provided the bunches can be treated as identical by their inner qualities (train theorem). If a flat feedback is strong enough, the transverse modes are single-bunch, provided the inter-bunch wakes are also flat (damper theorem).

  14. Correlation between morphological characters and estimated bunch ...

    African Journals Online (AJOL)

    The methodology of multiple linear regression (MLR) was used to estimate bunch weight. The most significant variables that were measured included number of leaves at harvest, number of fruits per bunch, FW, FL, rachis weight (RW) and stalk length (SL), generating the following prediction equation: BW= -5.249 + ...

  15. Femtosecond single electron bunch generation by rotating longitudinal bunch phase space in magnetic field

    International Nuclear Information System (INIS)

    Yang, J.; Kondoh, T.; Kan, K.; Kozawa, T.; Yoshida, Y.; Tagawa, S.

    2006-01-01

    A femtosecond (fs) electron bunching was observed in a photoinjector with a magnetic compressor by rotating the bunch in longitudinal phase space. The bunch length was obtained by measuring Cherenkov radiation of the electron beam with a femtosecond streak camera technique. A single electron bunch with rms bunch length of 98 fs was observed for a 32 MeV electron beam at a charge of 0.17 nC. The relative energy spread and the normalized transverse emittance of the electron beam were 0.2% and 3.8 mm-mrad, respectively. The effect of space charge on the bunch compression was investigated experimentally for charges from 0.17 to 1.25 nC. The dependences of the relative energy spread and the normalized beam transverse emittance on the bunch charge were measured

  16. Curvature radiation by bunches of particles

    International Nuclear Information System (INIS)

    Saggion, A.

    1975-01-01

    A bunch of relativistic particles moving on a curved trajectory is considered. The coherent emission of curvature radiation is described with particular regard to the role played by the 'shape' of the bunch as a function of its dimensions. It is found that the length of the bunch strongly affects the spectrum of the radiation emitted, with no effect on its polarization. For wavelengths shorter than the length of the bunch, the emitted intensity as a function of frequency shows recurrent maxima and minima, the height of the maxima being proportional to νsup(-5/3). The bunch dimensions perpendicular to the plane of the orbit affect both the spectral intensity and the polarization of the radiation. (orig./BJ) [de

  17. Feedback control of coupled-bunch instabilities

    International Nuclear Information System (INIS)

    Fox, J.D.; Eisen, N.; Hindi, H.; Linscott, I.; Oxoby, G.; Sapozhnikov, L.; Serio, M.

    1993-05-01

    The next generation of synchrotron light sources and particle accelerators will require active feedback systems to control multi-bunch instabilities. Stabilizing hundreds or thousands of potentially unstable modes in these accelerator designs presents many technical challenges. Feedback systems to stabilize coupled-bunch instabilities may be understood in the frequency domain (mode-based feedback) or in the time domain (bunch-by-bunch feedback). In both approaches an external amplifier system is used to create damping fields that prevent coupled-bunch oscillations from growing without bound. The system requirements for transverse (betatron) and longitudinal (synchrotron) feedback are presented, and possible implementation options developed. Feedback system designs based on digital signal-processing techniques are described. Experimental results are shown from a synchrotron oscillation damper in the SSRL/SLAC storage ring SPEAR that uses digital signal-processing techniques

  18. CORNELL: Bunch trains provide higher luminosity

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    The new colliding beam technique - ''bunch trains'' - at Cornell's electron-positron Storage Ring (CESR) has led to a new world record for colliding beam luminosity - 3.3 x 10 32 cm -2 s -1 . In the bid to increase reaction rate for any particular process, this luminosity is pushed as high as possible. Once all other luminosityincreasing cards have been played, the only practical way of making a large gain in luminosity is to increase the frequency of bunch-bunch collisions by increasing the number of bunches stored in the ring. However this is not without its own problems: • If the two beams travel the same orbit, the n bunches in one beam collide with the n bunches of the other at 2n points around the ring, and the resulting cumulative nonlinear beam-beam effect (tune shift) severely limits the luminosity attainable at any interaction point. • The destabilizing wakefield effects of bunches on each other increase as the number of bunches increases and the spacing between them decreases. • The synchrotron radiation emitted by the beams becomes a severe problem as the total beam current is raised: to overcome these effects means supplying radiofrequency power to maintain the beam energy, carrying away heat from the vacuum chamber walls, pumping out desorbed gases, and controlling Xray backgrounds in the experiment. In 1979, CESR was designed to run with a single bunch of electrons and a single bunch of positrons circulating on the same orbit and colliding head-on at two diametrically opposite points in the ring, where the CLEO and CUSB experiments were then located. Ideally one could store multiple bunches and solve the multiple collision point problem by using separate rings for the two beams, as in the CERN ISR proton-proton collider and in the original DORIS two-ring configuration at DESY, Hamburg, making the two beams intersect only at the experiments. A less expensive version of this two-ring scheme was accomplished at CESR in

  19. CORNELL: Bunch trains provide higher luminosity

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1995-09-15

    The new colliding beam technique - ''bunch trains'' - at Cornell's electron-positron Storage Ring (CESR) has led to a new world record for colliding beam luminosity - 3.3 x 10{sup 32} cm{sup -2}s{sup -1}. In the bid to increase reaction rate for any particular process, this luminosity is pushed as high as possible. Once all other luminosityincreasing cards have been played, the only practical way of making a large gain in luminosity is to increase the frequency of bunch-bunch collisions by increasing the number of bunches stored in the ring. However this is not without its own problems: • If the two beams travel the same orbit, the n bunches in one beam collide with the n bunches of the other at 2n points around the ring, and the resulting cumulative nonlinear beam-beam effect (tune shift) severely limits the luminosity attainable at any interaction point. • The destabilizing wakefield effects of bunches on each other increase as the number of bunches increases and the spacing between them decreases. • The synchrotron radiation emitted by the beams becomes a severe problem as the total beam current is raised: to overcome these effects means supplying radiofrequency power to maintain the beam energy, carrying away heat from the vacuum chamber walls, pumping out desorbed gases, and controlling Xray backgrounds in the experiment. In 1979, CESR was designed to run with a single bunch of electrons and a single bunch of positrons circulating on the same orbit and colliding head-on at two diametrically opposite points in the ring, where the CLEO and CUSB experiments were then located. Ideally one could store multiple bunches and solve the multiple collision point problem by using separate rings for the two beams, as in the CERN ISR proton-proton collider and in the original DORIS two-ring configuration at DESY, Hamburg, making the two beams intersect only at the experiments. A less expensive version of this two-ring scheme was accomplished at CESR in 1983, using

  20. Method and apparatus for control of coherent synchrotron radiation effects during recirculation with bunch compression

    Science.gov (United States)

    Douglas, David R; Tennant, Christopher

    2015-11-10

    A modulated-bending recirculating system that avoids CSR-driven breakdown in emittance compensation by redistributing the bending along the beamline. The modulated-bending recirculating system includes a) larger angles of bending in initial FODO cells, thereby enhancing the impact of CSR early on in the beam line while the bunch is long, and 2) a decreased bending angle in the final FODO cells, reducing the effect of CSR while the bunch is short. The invention describes a method for controlling the effects of CSR during recirculation and bunch compression including a) correcting chromatic aberrations, b) correcting lattice and CSR-induced curvature in the longitudinal phase space by compensating T.sub.566, and c) using lattice perturbations to compensate obvious linear correlations x-dp/p and x'-dp/p.

  1. Study of CSR longitudinal bunch compression cavity

    International Nuclear Information System (INIS)

    Yin Dayu; Li Peng; Liu Yong; Xie Qingchun

    2009-01-01

    The scheme of longitudinal bunch compression cavity for the Cooling Storage Ring (CSR)is an important issue. Plasma physics experiments require high density heavy ion beam and short pulsed bunch,which can be produced by non-adiabatic compression of bunch implemented by a fast compression with 90 degree rotation in the longitudinal phase space. The phase space rotation in fast compression is initiated by a fast jump of the RF-voltage amplitude. For this purpose, the CSR longitudinal bunch compression cavity, loaded with FINEMET-FT-1M is studied and simulated with MAFIA code. In this paper, the CSR longitudinal bunch compression cavity is simulated and the initial bunch length of 238 U 72+ with 250 MeV/u will be compressed from 200 ns to 50 ns.The construction and RF properties of the CSR longitudinal bunch compression cavity are simulated and calculated also with MAFIA code. The operation frequency of the cavity is 1.15 MHz with peak voltage of 80 kV, and the cavity can be used to compress heavy ions in the CSR. (authors)

  2. The 'Fresh-Bunch' technique in FELs

    International Nuclear Information System (INIS)

    Ben-Zvi, I.; Yang, K.M.; Yu, L.H.

    1991-01-01

    The 'Fresh Bunch' technique is being proposed as a method of increasing the gain and power of FEL amplifiers in which the length of the optical radiation pulse is shorter than the length of the electron bunch. In multi-stage FEL, electron beam energy spread is increased by the FEL interaction in the early stages. In the 'Fresh Bunch' technique, the low energy spread of the electron beam is recovered by shifting the radiation pulse to an undisturbed part of the electron bunch, thus improving the gain and trapping fraction in later stages. A test case for the application of the Fresh Bunch method is demonstrated by numerical simulation. In this particular example we examine a subharmonically seeded VUV Free-Electron Laser. We begin with the generation of harmonic radiation, which takes place over one part of the electron bunch. Then the radiation is shifted by means of a strong dispersive section to a fresh part of the bunch for exponential amplification and tapered wiggler amplification. By starting over with a new ensemble of electrons, the energy spread introduced by the bunching in the fundamental is removed, leading to an increased gain. Furthermore, it is possible to use a much stronger seed in the fundamental without incurring the penalty of a large energy spread later on. We note that more than a single application of the 'Fresh Bunch' method may be done in a single FEL multiplier-amplifier. Thus x-ray wavelengths may be reached by successive multiplication in a chain of FEL amplifiers starting from a tunable seed laser. 5 refs., 2 figs., 2 tabs

  3. Observation of coherently enhanced tunable narrow-band terahertz transition radiation from a relativistic sub-picosecond electron bunch train

    International Nuclear Information System (INIS)

    Piot, P.; Maxwell, T. J.; Sun, Y.-E; Ruan, J.; Lumpkin, A. H.; Thurman-Keup, R.; Rihaoui, M. M.

    2011-01-01

    We experimentally demonstrate the production of narrow-band (δf/f≅20% at f≅0.5THz) transition radiation with tunable frequency over [0.37, 0.86] THz. The radiation is produced as a train of sub-picosecond relativistic electron bunches transits at the vacuum-aluminum interface of an aluminum converter screen. The bunch train is generated via a transverse-to-longitudinal phase space exchange technique. We also show a possible application of modulated beams to extend the dynamical range of a popular bunch length diagnostic technique based on the spectral analysis of coherent radiation.

  4. Sensitivity of the CSR self-interaction to the local longitudinal charge concentration of an electron bunch

    CERN Document Server

    Li, R

    2001-01-01

    Recent measurements of the coherent synchrotron radiation (CSR) effects indicated that the observed emittance growth and energy modulation due to the orbit-curvature-induced bunch self-interaction are sometimes bigger than predictions based on Gaussian longitudinal charge distributions. In this paper, by performing a model study, we show both analytically and numerically that when the longitudinal bunch charge distribution involves concentration of charges in a small fraction of the bunch length, enhancement of the CSR self-interaction beyond the Gaussian prediction may occur. The level of this enhancement is sensitive to the level of the local charge concentration.

  5. Sensitive beam-bunch phase detector

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, S; Shepard, K W

    1984-11-15

    A sensitive heavy-ion beam-bunch phase detector has been developed by first examining the relationship between the sensitivity of an rf resonant cavity as a particle bunch detector and the shunt impedance of the same cavity as an accelerating structure. Then the various high shunt impedance rf cavities previously developed for accelerating heavy ions were evaluated for use as bunch detectors. A spiral-loaded geometry was chosen, built, and tested with beam. The sensitivity obtained, 14 V per electrical nA of beam, is a factor 3 higher than previously reported. (orig.).

  6. Sensitive beam-bunch phase detector

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, S; Shepard, K W [Argonne National Lab., IL (USA). Physics Div.

    1984-11-15

    A sensitive heavy-ion beam-bunch phase detector has been developed by first examining the relationship between the sensitivity of an RF resonant cavity as a particle bunch detector and the shunt impedance of the same cavity as an accelerating structure. Then the various high shunt impedance RF cavities previously developed for accelerating heavy ions were evaluated for use as bunch detectors. A spiral-loaded geometry was chosen, built, and tested with beam. The sensitivity obtained, 14 ..mu.. V per electrical nA of beam, is a factor 3 higher than previously reported.

  7. Bunch Compression Stability Dependence on RF Parameters

    CERN Document Server

    Limberg, T

    2005-01-01

    In present designs for FEL's with high electron peak currents and short bunch lengths, higher harmonic RF systems are often used to optimize the final longitudinal charge distributions. This opens degrees of freedom for the choice of RF phases and amplitudes to achieve the necessary peak current with a reasonable longitudinal bunch shape. It had been found empirically that different working points result in different tolerances for phases and amplitudes. We give an analytical expression for the sensitivity of the compression factor on phase and amplitude jitter for a bunch compression scheme involving two RF systems and two magnetic chicanes as well numerical results for the case of the European XFEL.

  8. Experimental demonstration of the KEK induction synchrotron

    International Nuclear Information System (INIS)

    Takayama, Ken; Torikai, Kota; Shimosaki, Yoshito; Kono, Tadaaki; Iwashita, Taiki; Arakida, Yoshio; Nakamura, Eiji; Shirakata, Masashi; Sueno, Takeshi; Wake, Masayoshi; Otsuka, Kazunori

    2007-01-01

    Recent progress in the KEK induction synchrotron is presented. In the recent experiment, by using a newly developed induction acceleration system instead of radio-wave acceleration devices, a single proton bunch injected from the 500 MeV Booster ring and captured by the barrier bucket created by the induction step-voltages was accelerated to 6 GeV in the KEK proton synchrotron

  9. Down sampled signal processing for a B Factory bunch-by-bunch feedback system

    International Nuclear Information System (INIS)

    Hindi, H.; Hosseini, W.; Briggs, D.; Fox, J.; Hutton, A.

    1992-03-01

    A bunch-by-bunch feedback scheme is studied for damping coupled bunch synchrotron oscillations in the proposed PEP II B Factory. The quasi-linear feedback systems design incorporates a phase detector to provide a quantized measure of bunch phase, digital signal processing to compute an error correction signal and a kicker system to correct the energy of the bunches. A farm of digital processors, operating in parallel, is proposed to compute correction signals for the 1658 bunches of the B Factory. This paper studies the use of down sampled processing to reduce the computational complexity of the feedback system. We present simulation results showing the effect of down sampling on beam dynamics. Results show that down sampled processing can reduce the scale of the processing task by a factor of 10

  10. Longitudinal bunch deformation of a multi-bunched beam in the TRISTAN Accumulation Ring

    International Nuclear Information System (INIS)

    Obina, T.; Satoh, K.; Kasuga, T.; Funakoshi, Y.; Tobiyama, M.

    1997-01-01

    A remarkable bunch deformation has been observed in the TRISTAN Accumulation Ring (AR) during multi-bunch operations. When two bunches that have different populations are stored in the ring, the bunch length of the weaker bunch is longer than that of the stronger one. The phenomenon can be explained as an effect of wake fields due to higher-order modes (HOMs) of accelerating cavities. We tried to find out the frequency of the mode and the strength of the wake field, and introduced a new technique called a test bunch measurement. The estimated field strength from the experiment shows a reasonable agreement with the calculation of HOM impedance. copyright 1997 American Institute of Physics

  11. Operational performance of a bunch by bunch digital damper in the Fermilab Main Injector

    International Nuclear Information System (INIS)

    Adamson, P.; Ashmanskas, W.J.; Foster, G.W.; Hansen, S.; Marchionni, A.; Nicklaus, D.; Semenov, A.; Wildman, D.; Kang, H.

    2005-01-01

    We have implemented a transverse and longitudinal bunch by bunch digital damper system in the Fermilab Main Injector, using a single digital board for all 3 coordinates. The system has been commissioned over the last year, and is now operational in all MI cycles, damping beam bunched at both 53MHz and 2.5MHz. We describe the performance of this system both for collider operations and high-intensity running for the NuMI project

  12. ANALYSIS OF PROCESSES IN AN INDEPENDENT GENERATOR WITH A NONCONTACT CASCADE THREE-PHASE MODULATED EXCITER VIA A STAR-CONNECTED CIRCUIT WITH A COMMON MODULATOR PHASE CONNECTION UNDER OPERATION TO AN INDUCTION MOTORS SITE

    Directory of Open Access Journals (Sweden)

    K.M. Vasyliv

    2013-04-01

    Full Text Available By means of a mathematical experiment, electromagnetic and electromechanical processes in an independent electric power supply system based on an asynchronized generator with a three-phase modulated exciter are investigated. The processes are analyzed to specify the working capacity of the power supply system during its operation to an induction motors site. Regularities of the electromagnetic and electromechanical processes behavior versus load intensity and the switch control system parameters are identified.

  13. Observations of bunch-by-bunch losses in the 2010 LHC proton physics operation

    CERN Document Server

    Papotti, G

    2011-01-01

    This document summarizes the bunch-by-bunch loss observations carried out during the 2010 proton physics run at the LHC. These observations proved beneficial to the improvement of operations, in particular in the early days of nominal intensity per bunch operation: then the plots initiated the removal of the tune split and motivated the modification of a filling scheme to remove parasitic encounters that heightened the losses on selected bunches. Along with plots from sample physics fills, summary plots for the year are shown. The colour coding is always chosen so to highlight the dependence of the losses on the filling scheme.

  14. Bunch-by-bunch longitudinal feedback system for PEP-II

    International Nuclear Information System (INIS)

    Oxoby, G.; Claus, R.; Fox, J.

    1994-06-01

    This paper describes the implementation of the bunch-by-bunch longitudinal feedback system for the PEP-II B Factory. Bunch spacing down to 2 ns is achieved using 500 Megasamples per second A/D and D/A converters, and AT ampersand T 1610 Digital Signal Processors are integrated to run a downsampled feedback algorithm for each bunch in parallel. This general purpose programmable system, packaged in VXI and VME, is modular and scalable to offer portability to other accelerator rings. The control and monitoring hardware and software architecture have been developed to provide ease of operation as well as diagnostic tools for machine physics

  15. Generation and measurement of velocity bunched ultrashort bunch of pC charge

    Directory of Open Access Journals (Sweden)

    X. H. Lu

    2015-03-01

    Full Text Available In this paper, we discuss the velocity compression in a short rf linac of an electron bunch from a rf photoinjector operated in the blowout regime. Particle tracking simulations shows that with a beam charge of 2 pC an ultrashort bunch duration of 16 fs can be obtained at a tight longitudinal focus downstream of the linac. A simplified coherent transition radiation (CTR spectrum method is developed to enable the measurement of ultrashort (sub-50 fs bunches at low bunch energy (5 MeV and low bunch charges (<10  pC. In this method, the ratio of the radiation energy selected by two narrow bandwidth filters is used to estimate the bunch length. The contribution to the coherent form factor of the large transverse size of the bunch suppresses the radiation signal significantly and is included in the analysis. The experiment was performed at the UCLA Pegasus photoinjector laboratory. The measurement results show bunches of sub-40 fs with 2 pC of charge well consistent with the simulation using actual experimental conditions. These results open the way to the generation of ultrashort bunches with time-duration below 10 fs once some of the limitations of the setup (rf phase jitter, amplitude instability and low field in the gun limited by breakdown are corrected.

  16. Considerations of bunch-spacing options for multi-bunch operation of the Tevatron Collider

    International Nuclear Information System (INIS)

    Dugan, G.

    1989-01-01

    This discussion will consider a number of points relevant to limitations, advantages and disadvantages of various arrangements of bunches in the Tevatron proton-antiproton collider. The considerations discussed here will be limited to: (a) bunch spacing symmetry and relation to the relative luminosity at B0 and D0 and the beam-beam interaction with separated beams; (b) bunch spacing constraints imposed by Main Ring RF coalescing and the optics of beam separation at B0 and D0; and (c) bunch spacing constraints imposed by injection and abort kicker timing requirements, and by the Antiproton Source RF unstacking process. 20 figs., 17 tabs

  17. Curvature-Induced Bunch Self-Interaction for an Energy-Chirped Bunch in Magnetic Bends

    International Nuclear Information System (INIS)

    Rui Li

    2008-01-01

    Within the realm of classical electrodynamics, the curvature-induced bunch collective interaction in magnetic bends can be studied using effective forces in the canonical formulation of the coherent synchrotron radiation (CSR) effect. As an application of this canonical formulation, in this paper, for an electron distribution moving ultrarelativistically in a bending system, the dynamics of the particles in the distribution is derived from the Hamiltonian of the particles in terms of the bunch internal coordinates. The consequent Vlasov equation manifests explicitly how the phase-space distribution is perturbed by the effective CSR forces. In particular, we study the impact of an initial linear energy chirp of the bunch on the behavior of the effective longitudinal CSR force, which arises due to the modification of the retardation relation as a result of the energy-chirping-induced longitudinal-horizontal correlation of the bunch distribution (bunch tilt) in dispersive regions. Our study demonstrates clearly the time delay (or retardation) of the behavior of the effective longitudinal CSR force on a bunch in responding to the change of the bunch length in a magnetic bend. Our result also shows that the effective longitudinal CSR force for a bunch under full compression can have sensitive dependence on the transverse position of the test particle in the bunch for certain parameter regimes

  18. Space Charge Mitigation by Hollow Bunches

    CERN Multimedia

    Oeftiger, AO

    2014-01-01

    To satisfy the requirements of the HL-LHC (High Luminosity Large Hadron Collider), the LHC injector chain will need to supply a higher brightness, i.e. deliver the same transverse beam emittances \\epsilon_{x,y} while providing a higher intensity N. However, a larger number of particles per bunch enhances space charge effects. One approach to mitigate the impact of space charge is to change the longitudinal phase space distribution: hollow bunches feature a depleted bunch centre and a densely populated periphery. Thus, the spatial line density maximum is depressed which ultimately decreases the tune spread imposed by space charge. Therefore, a higher intensity can be accepted while keeping the same overall space charge tune shift. 3 different methods to create hollow bunches in the PSBooster are simulated.

  19. Single bunched beam generation without subharmonic prebuncher

    International Nuclear Information System (INIS)

    Kobayashi, T.; Tagawa, S.

    1995-01-01

    The intensity of the accelerated single bunched electron beam depends on the performance of the electron gun and the fast cathode pulser. The electron beam is emitted by a Y-796 cathode assembly with a cathode of 2 cm 2 (8 A/cm 2 ), and an extracted voltage of 90 kV. The maximum charge of the single bunched beam was attained at 1.5 nC/pulse using SHB. Recently, a single bunched beam has been generated by an ultrafast cathode pulser (rise and fall time <100 ps pulse height -2 kV at 50 Ω) without SHB. The charge of the accelerated electron beam is about 40 pC/pulse (pulse width <10 ps) without the production of a satellite beam. This result show that a single bunched beam can be produced by the linear accelerator without SHB. ((orig.))

  20. Luminosity with more bunches in PEP

    International Nuclear Information System (INIS)

    Corbett, W.J.

    1990-12-01

    The near term accelerator physics program for PEP includes experiments in a collider mode with up to 9 bunches in each beam. In this memo, luminosity data from the 3 x 3 configuration is first used to calculate vertical beam size, emittance and tune shift as a function of current. The data is then used to extrapolate to the case with either 6 x 6 or 9 x 9 bunches colliding in PEP. Vertical emittance growth from the separated bunch optics and dispersion at the IP are included in the calculations. The conclusion is that given a 90 mA current drive limitation in PEP, operating with 6 x 6 bunches yields the maximum luminosity. 9 refs., 6 figs

  1. CERN: The best of the bunch

    Energy Technology Data Exchange (ETDEWEB)

    Gagliardi, F.

    1992-10-15

    As other factors governing the electron-positron collision rate in CERN's LEP 27-kilometre storage ring reach their limit, one way of coaxing the collision rate higher is to increase the number of bunches stored in the ring.

  2. Space Charge Mitigation With Longitudinally Hollow Bunches

    CERN Multimedia

    Oeftiger, Adrian; Rumolo, Giovanni

    2016-01-01

    Hollow longitudinal phase space distributions have a flat profile and hence reduce the impact of transverse space charge. Dipolar parametric excitation with the phase loop feedback systems provides such hollow distributions under reproducible conditions. We present a procedure to create hollow bunches during the acceleration ramp of CERN’s PS Booster machine with minimal changes to the operational cycle. The improvements during the injection plateau of the downstream Proton Synchrotron are assessed in comparison to standard parabolic bunches.

  3. Application accelerator system having bunch control

    International Nuclear Information System (INIS)

    Wang, D.; Krafft, G.A.

    1999-01-01

    An application accelerator system for monitoring the gain of a free electron laser is disclosed. Coherent Synchrotron Radiation (CSR) detection techniques are used with a bunch length monitor for ultra short, picosec to several tens of femtosec, electron bunches. The monitor employs an application accelerator, a coherent radiation production device, an optical or beam chopping device, an infrared radiation collection device, a narrow-banding filter, an infrared detection device, and a control. 1 fig

  4. Application accelerator system having bunch control

    Science.gov (United States)

    Wang, Dunxiong; Krafft, Geoffrey Arthur

    1999-01-01

    An application accelerator system for monitoring the gain of a free electron laser. Coherent Synchrotron Radiation (CSR) detection techniques are used with a bunch length monitor for ultra short, picosec to several tens of femtosec, electron bunches. The monitor employs an application accelerator, a coherent radiation production device, an optical or beam chopping device, an infrared radiation collection device, a narrow-banding filter, an infrared detection device, and a control.

  5. 5-HT4-receptors modulate induction of long-term depression but not potentiation at hippocampal output synapses in acute rat brain slices.

    Directory of Open Access Journals (Sweden)

    Matthias Wawra

    Full Text Available The subiculum is the principal target of CA1 pyramidal cells and mediates hippocampal output to various cortical and subcortical regions of the brain. The majority of subicular pyramidal cells are burst-spiking neurons. Previous studies indicated that high frequency stimulation in subicular burst-spiking cells causes presynaptic NMDA-receptor dependent long-term potentiation (LTP whereas low frequency stimulation induces postsynaptic NMDA-receptor-dependent long-term depression (LTD. In the present study, we investigate the effect of 5-hydroxytryptamine type 4 (5-HT4 receptor activation and blockade on both forms of synaptic plasticity in burst-spiking cells. We demonstrate that neither activation nor block of 5-HT4 receptors modulate the induction or expression of LTP. In contrast, activation of 5-HT4 receptors facilitates expression of LTD, and block of the 5-HT4 receptor prevents induction of short-term depression and LTD. As 5-HT4 receptors are positively coupled to adenylate cyclase 1 (AC1, 5-HT4 receptors might modulate PKA activity through AC1. Since LTD is blocked in the presence of 5-HT4 receptor antagonists, our data are consistent with 5-HT4 receptor activation by ambient serotonin or intrinsically active 5-HT4 receptors. Our findings provide new insight into aminergic modulation of hippocampal output.

  6. COMMISSIONING OF THE DIGITAL TRANSVERSE BUNCH-BY-BUNCH FEEDBACK SYSTEM FOR THE TLS

    International Nuclear Information System (INIS)

    HU, K.H.; KUO, C.H.; CHOU, P.J.; LEE, D.; HSU, S.Y.; CHEN, J.; WANG, C.J.; HSU, K.T.; KOBAYASHI, K.; NAKAMURA, T.; CHAO, A.W.; WENG, W.T.

    2006-01-01

    Multi-bunch instabilities degrade beam quality through increased beam emittance, energy spread and even beam loss. Feedback systems are used to suppress multi-bunch instabilities associated with the resistive wall of the beam ducts, cavity-like structures, and trapped ions. A new digital transverse bunch-by-bunch feedback system has recently been commissioned at the Taiwan Light Source, and has replaced the previous analog system. The new system has the advantages that it enlarges the tune acceptance and improves damping for transverse instability at high currents, such that top-up operation is achieved. After a coupled-bunch transverse instability was suppressed, more than 350 mA was successfully stored during preliminary commissioning. In this new system, a single feedback loop simultaneously suppresses both horizontal and vertical multi-bunch instabilities. Investigating the characteristics of the feedback loop and further improving the system performances are the next short-term goals. The feedback system employs the latest generation of field-programmable gate array (FPGA) processor to process bunch signals. Memory has been installed to capture up to 250 msec of bunch oscillation signal, considering system diagnostics suitable to support various beam physics studies

  7. Extremely short relativistic-electron-bunch generation in the laser wakefield via novel bunch injection scheme

    NARCIS (Netherlands)

    Khachatryan, A.G.; van Goor, F.A.; Boller, Klaus J.; Reitsma, A.J.W.; Jaroszynski, D.A.

    2004-01-01

    Recently a new electron-bunch injection scheme for the laser wakefield accelerator has been proposed [JETP Lett. 74, 371 (2001); Phys. Rev. E 65, 046504 (2002)]. In this scheme, a low energy electron bunch, sent in a plasma channel just before a high-intensity laser pulse, is trapped in the laser

  8. Beam diagnostics based on time-domain bunch-by-bunch data

    International Nuclear Information System (INIS)

    Teytelman, D.; Fox, J.; Hindi, H.; Limborg, C.; Linscott, I.; Prabhakar, S.; Sebek, J.; Young, A.; Drago, A.; Serio, M.; Barry, W.; Stover, G.

    1998-01-01

    A bunch-by-bunch longitudinal feedback system has been used to control coupled-bunch longitudinal motion and study the behavior of the beam at ALS, SPEAR, PEP-II, and DAΦNE. Each of these machines presents unique challenges to feedback control of unstable motion and data analysis. Here we present techniques developed to adapt this feedback system to operating conditions at these accelerators. A diverse array of techniques has been developed to extract information on different aspects of beam behavior from the time-domain data captured by the feedback system. These include measurements of growth and damping rates of coupled-bunch modes, bunch-by-bunch current monitoring, measurements of bunch-by-bunch synchronous phases and longitudinal tunes, and beam noise spectra. A technique is presented which uses the longitudinal feedback system to measure transverse growth and damping rates. Techniques are illustrated with data acquired at all of the four above-mentioned machines. copyright 1998 American Institute of Physics

  9. Longitudinal study of group a bunch of electrons in a linear accelerator

    International Nuclear Information System (INIS)

    Ben Taghalline, Ines; Ben Khedher, Rihab

    2009-01-01

    For an effective use of the electron beam, the energy dispersion shall have to be the weakest possible on the other hand the beam intensity owes shall be the biggest possible. In the practice these parameters depended of the bunching elements in the accelerator. The first part of our work presents studies concerning the influence of the modulation tension in the cavity and the drift space length on the bunching quality. The second part of this study is related to development an algorithm dedicated to determine the RF and geometrical parameters which influence the bunching quality. The studied case is a cavity followed by a drift space. The result obtained by application this algorithm is in good agreement with the others simulations result.

  10. Transport of dc and bunched beams through a 25 MV folded tandem accelerator

    International Nuclear Information System (INIS)

    Milner, W.T.; Alton, G.D.; Hensley, D.C.; Jones, C.M.; King, R.F.; Larson, J.D.; Moak, C.D.; Sayer, R.O.

    1975-01-01

    Studies of beam transport through the planned ORNL 25 MV folded tandem accelerator demonstrate efficient utilization of phase-space acceptance and the feasibility of injecting bunched beams from the tandem accelerator into the Oak Ridge Isochronous Cyclotron (ORIC). Use of a 180 0 bending magnet in the terminal provides outstanding charge state selection and permits better control of the high-energy beam transport than has previously been possible in conventional tandem accelerators. Time spreads introduced in bunched beams by the 180 0 magnet are kept within a 6 0 RF acceptance window at ORIC provided the beam has a crossover in the center of the 180 0 magnet. Ion masses from 12 to 240 amu, preinjection energies from 150 to 500 keV and terminal voltages from 7.5 to 25 MV were studied for dc beams and beams bunched by various modulation techniques. (U.S.)

  11. Computer modelling of bunch-by-bunch feedback for the SLAC B-factory design

    International Nuclear Information System (INIS)

    Briggs, D.; Fox, J.D.; Hosseini, W.; Klaisner, L.; Morton, P.; Pellegrin, J.L.; Thompson, K.A.; Lambertson, G.

    1991-05-01

    The SLAC B-factory design, with over 1600 high current bunches circulating in each ring, will require a feedback system to avoid coupled-bunch instabilities. A computer model of the storage ring, including the RF system, wave fields, synchrotron radiation loss, and the bunch-by-bunch feedback system is presented. The feedback system model represents the performance of a fast phase detector front end (including system noise and imperfections), a digital filter used to generate a correction voltage, and a power amplifier and beam kicker system. The combined ring-feedback system model is used to study the feedback system performance required to suppress instabilities and to quantify the dynamics of the system. Results are presented which show the time development of coupled bunch instabilities and the damping action of the feedback system. 3 refs., 5 figs., 2 tabs

  12. Longitudinal schottky spectra of a bunched Ne10+ ion beam at the CSRe

    International Nuclear Information System (INIS)

    Wen Weiqiang; Ma Xinwen; Zhang Dacheng

    2013-01-01

    The longitudinal Schottky spectra of a radio-frequency (RF) bunched and electron cooled 22Ne 10+ ion beam at 70 MeV/u have been studied by a newly installed resonant Schottky pick-up at the experimental cooler storage ring (CSRe), at IMP. For an RF-bunched ion beam, a longitudinal momentum spread of Δp/p=1.6 × 10 -5 has been reached with less than 107 stored ions. The reduction of momentum spread compared with a coasting ion beam was observed from Schottky noise signal of the bunched ion beam. In order to prepare the future laser cooling experiment at the CSRe, the RF-bunching power was modulated at 25 th , 50 th and 75 th harmonic of the revolution frequency, effective bunching amplitudes were extracted from the Schottky spectrum analysis. Applications of Schottky noise for measuring beam lifetime with ultra-low intensity of ion beams are presented, and it is relevant to upcoming experiments on laser cooling of relativistic heavy ion beams and nuclear physics at the CSRe. (authors)

  13. Study Modules for Calculus-Based General Physics. [Includes Modules 31-34: Inductance; Wave Properties of Light; Interference; and Introduction to Quantum Physics].

    Science.gov (United States)

    Fuller, Robert G., Ed.; And Others

    This is Part of a series of 41 Calculus Based Physics (CBP) modules totaling about 1,000 Pages. The modules include study guides, practice tests, and mastery tests for a full-year individualized courses in calculus-based physics based on the Personalized System of Instruction (PSI). The units are not intended to be used without outside materials;…

  14. ''High intensity per bunch'' working group

    International Nuclear Information System (INIS)

    2001-01-01

    Third Generation Light Sources are supposed to store high intensity beams not only in many tightly spaced bunches (multibunch operation), but also in few bunch or even single lunch modes of operation, required for example for time structure experiments. Single bunch instabilities, driven by short-range wake fields, however spoil the beam quality, both longitudinally and transversely. Straightforward ways of handling them, by pushing up the chromaticity (ζ = ΔQ/(Δp/p)) for example, enabled to raise the charge per bunch, but to the detriment of beam lifetime. In addition, since the impedance of the vacuum chamber deteriorates with the installation of new insertion devices, the current thresholds tend to dope down continuously. The goal of this Working Group was then to review these limitations in the existing storage rings, where a large number of beam measurements have been performed to characterise them, and to discuss different strategies which are used against them. About 15 different laboratories reported on the present performance of storage rings, experiences gained in high charge per bunch, and on simulation results and theoretical studies. More than 25 presentations addressed the critical issues and stimulated the discussion. Four main topics came out: - Observation and experimental data; - Impedance studies and tracking codes; - Theoretical investigations; - Cures and feedback. (author)

  15. Bunch compression for an FEL at NLCTA

    International Nuclear Information System (INIS)

    Zimmermann, F.

    1997-04-01

    As part of the design effort for a free electron laser driven by the Next Linear Collider Test Accelerator (NLCTA), the author reports studies of bunch-length compression utilizing the existing infrastructure and hardware. In one possible version of the NLCTA FEL, bunches with 900-microm FWHM length, generated by an S-band photo-injector, would be compressed to an rms length of 60--120 microm before entering the FEL undulator. It is shown that, using the present magnetic chicane, the bunch compression is essentially straightforward, and that almost all emittance-diluting effects, e.g. wakefields, chromaticity, or space charge in the bending magnets, are small. The only exception to this finding is the predicted increase of the horizontal emittance due to coherent synchrotron radiation (CSR). Estimates based on existing theories of coherent synchrotron radiation suggest a tripling or quadrupling of the initial emittance, which seems to preclude bunch compression during regular FEL operation. Serendipitously, the magnitude of the predicted emittance growth would, on the other hand, make the NLCTA chicane an excellent tool for measuring the effects of coherent synchrotron radiation. This will be of considerable interest to many future projects, in particular to the Linac Coherent Light Source (LCLS). As an aside, it is shown that coherent synchrotron radiation in a bending magnet gives rise to a minimum possible bunch length, which is very reminiscent of the Oide limit on the vertical spot size at the interaction point of a linear collider

  16. Influence of laser parameters on the relativistic short electron bunches dynamics in linear accelerators based on RF-guns and development of associated diagnostics

    International Nuclear Information System (INIS)

    Vinatier, T.

    2015-01-01

    My thesis investigates dynamics and diagnostics related to short electron bunches, namely whose rms duration is not directly measurable by an electronic method locating the border at a few tens of picoseconds. The short nature of the bunch and the necessity of a high peak current for the applications imply strong space-charge forces leading to a degradation of beam properties, as its transverse emittance and duration. The main difficulty is to characterize, model and take into account these effects. The chapter 2 consists in the measurements of several properties of these bunches: charge, transverse emittance, energy and duration. The originality of my work is that I use simple methods, both on the theoretical (analytical at maximum) and technological (using only common elements of electron accelerators) point of view. I have developed a method of charge measurement from the measurement of the light intensity emitted by a scintillating screen following the interaction with an electron beam. I have also developed a method to measure the bunch mean energy with a steering magnet and a scintillating screen, via the displacement of the bunch centroid as a function of the field of the steering magnet. I have also adapted multi-parametric methods to measure the transverse emittance and duration of electron bunches. These indirect methods allow the determination of these properties from the measurement of other more accessible properties: the transverse dimensions for the transverse emittance and the energy spread for the duration. The chapter 3 consists in the comparison of the properties of short electron beams, single or longitudinally modulated, generated by 3 different methods: Injection of a short or longitudinally modulated laser pulse in an RF-gun; Magnetic compression in a chicane; and RF-compression in an accelerating structure (Velocity Bunching). I have shown that, at equal conditions of charge, the generation of short bunches thanks to a short laser pulse

  17. Focusing of relativistic electron bunch, moving in cylindrical plasma waveguide

    International Nuclear Information System (INIS)

    Amatuni, A.Ts.; Ehlbakyan, S.S.; Sekhpossyan, E.V.

    1994-01-01

    The problem on the focusing of electron bunches moving with the relativistic velocity along the axis of cylindrical overdense plasma waveguide with the conducting internal surface is considered. The existence of periodic and nonperiodic components of the fields, generated in the plasma is shown. The conditions of electron bunch self-focusing by transverse electrical field and azimuthal magnetic field are derived. The possibility of the acceleration and focusing of electron or positron bunches by driving electron bunch wake field is discussed. The conditions, when the bunch in plasma waveguide moves without wake fields generating are obtained, which could be of the interest for the transport of relativistic electron (positron) bunches. 5 refs

  18. A new method for compensation of the effect of charging transformer's leakage inductance on PFN voltage regulation in Klystron pulse modulators

    Energy Technology Data Exchange (ETDEWEB)

    Patel, Akhil, E-mail: akhilpatel@rrcat.gov.in; Kale, Umesh; Shrivastava, Purushottam

    2017-04-21

    The Line type modulators have been widely used to generate high voltage rectangular pulses to power the klystron for high power RF generation. In Line type modulator, the Pulse Forming Network (PFN) which is a cascade combination of lumped capacitors and inductors is used to store the electrical energy. The charged PFN is then discharged into a klystron by firing a high voltage Thyratron switch. This discharge generates a high voltage rectangular pulse across the klystron electrodes. The amplitude and phase of Klystron's RF output is governed by the high voltage pulse amplitude. The undesired RF amplitude and phase stability issues arises at the klystron's output due to inter-pulse and during the pulse amplitude variations. To reduce inter-pulse voltage variations, the PFN is required to be charged at the same voltage after every discharge cycle. At present, the combination of widely used resonant charging and deQing method is used to regulate the pulse to pulse PFN voltage variations but the charging transformer's leakage inductance puts an upper bound on the regulation achievable by this method. Here we have developed few insights of the deQing process and devised a new compensation method to compensate this undesired effect of charging transformer's leakage inductance on the pulse to pulse PFN voltage stability. This compensation is accomplished by the controlled partial discharging of the split PFN capacitor using a low voltage MOSFET switch. Theoretically, very high values of pulse to pulse voltage stability may be achieved using this method. This method may be used in deQing based existing modulators or in new modulators, to increase the pulse to pulse voltage stability, without having a very tight bound on charging transformer's leakage inductance. Given a stable charging power supply, this method may be used to further enhance the inter-pulse voltage stability of modulators which employ the direct charging, after replacing the

  19. BBAT: Bunch and bucket analysis tool

    International Nuclear Information System (INIS)

    Deng, D.P.

    1995-01-01

    BBAT is written to meet the need of an interactive graphical tool to explore the longitudinal phase space. It is driven for testing new ideas or new tricks quickly. It is especially suitable for machine physicists or operation staff as well both in the control room during machine studies or off-line to analyze the data. The heart of the package contains a set of c-routines to do the number crunching. The graphics part is wired with scripting language tcl/tk and BLT. The c-routines are general enough that one can write new applications such as animation of the bucket as a machine parameter varies via a sliding scale. BBAT deals with single rf system. For double rf system, one can use Dr. BBAT, which stands for Double rf Bunch and Bucket Analysis Tool. One usage of Dr. BBAT is to visualize the process of bunch coalescing and flat bunch creation

  20. Note on polarized RHIC bunch arrangement

    International Nuclear Information System (INIS)

    Underwood, D.

    1996-01-01

    We discuss what combinations of bunch polarization in the two RHIC rings are necessary to do the physics measurements at various interaction regions. We also consider the bunches for both the pion inclusive and p-p elastic polarization measurements. Important factors to consider are the direction of the polarization with respect to the momentum in each bunch, the beam gas backgrounds, and the simulation of zero - polarization in one beam by averaging + and - helicity, and luminosity monitoring for normalization. These considerations can be addressed by setting the relative number of each of the 9 combinations possible at each of the 6 interaction regions. The combinations are (+ empty -) yellow X (+ empty -)blue, where yellow and blue are the counter-rotating rings

  1. Energy Efficiency of Induction Motors Running Off Frequency Converters with Pulse-Width Voltage Modulation{sup 1}

    Energy Technology Data Exchange (ETDEWEB)

    Shvetsov, N. K., E-mail: elmash@em.ispu.ru [V. I. Lenin Ivanovo State Power University (Russian Federation)

    2016-11-15

    The results of calculations of the increase in losses in an induction motor with frequency control and different forms of the supply voltage are presented. The calculations were performed by an analytic method based on harmonic analysis of the supply voltage as well as numerical calculation of the electromagnetic processes by the finite-element method.

  2. Different charges in the same bunch train at the European XFEL

    Energy Technology Data Exchange (ETDEWEB)

    Kot, Yauhen; Limberg, Torsten; Zagorodnov, Igor

    2013-11-15

    The injector of the European XFEL was initially designed for the operation with 1nC bunch charges. Later the flexibility of the nominal design of the injector with respect to the bunch charge was studied and extended also for smaller bunch charges down to 20 pC. A very tempting upgrade of this extension would be the operation of the European XFEL with different charges in the same train. It would make it suitable also for the experiments which require simultaneously different SASE pulse length or radiation power. Operation of two bunches within the same train sets new requirements on the working points of the injector which are to be satisfied additionally to the ones of a single charge operation. From the beam dynamics point of view here is to mention the similarity of the beam optical functions after the first accelerating module and suitable for lasing shapes of both bunches in the train at the end of the linac. Due to different charges and thus to different space charge forces which act on bunches during the passage of the linac the last condition cannot be easily satisfied even if the similarity of optical functions at the beginning of the linac is achieved. A more subtle analysis of the interplay between mismatch of beam optical functions, emittance growth in the injector and different 6D beam dynamics in the linac is needed with the final goal of successful lasing of both charges. In this paper we have investigated the possibility of the operation of different charges in the bunch train for the nominal design of the injector and for the case that it is extended by an additional laser system on the cathode. We have examined the problem of similarity of beam optical functions for different bunches in a train. We report also about the sensitivity of the beam optical functions on the chosen compression scenario and give an overview over the working points for the settings at the injector for single charge operation as well as combined working points for

  3. Different charges in the same bunch train at the European XFEL

    International Nuclear Information System (INIS)

    Kot, Yauhen; Limberg, Torsten; Zagorodnov, Igor

    2013-11-01

    The injector of the European XFEL was initially designed for the operation with 1nC bunch charges. Later the flexibility of the nominal design of the injector with respect to the bunch charge was studied and extended also for smaller bunch charges down to 20 pC. A very tempting upgrade of this extension would be the operation of the European XFEL with different charges in the same train. It would make it suitable also for the experiments which require simultaneously different SASE pulse length or radiation power. Operation of two bunches within the same train sets new requirements on the working points of the injector which are to be satisfied additionally to the ones of a single charge operation. From the beam dynamics point of view here is to mention the similarity of the beam optical functions after the first accelerating module and suitable for lasing shapes of both bunches in the train at the end of the linac. Due to different charges and thus to different space charge forces which act on bunches during the passage of the linac the last condition cannot be easily satisfied even if the similarity of optical functions at the beginning of the linac is achieved. A more subtle analysis of the interplay between mismatch of beam optical functions, emittance growth in the injector and different 6D beam dynamics in the linac is needed with the final goal of successful lasing of both charges. In this paper we have investigated the possibility of the operation of different charges in the bunch train for the nominal design of the injector and for the case that it is extended by an additional laser system on the cathode. We have examined the problem of similarity of beam optical functions for different bunches in a train. We report also about the sensitivity of the beam optical functions on the chosen compression scenario and give an overview over the working points for the settings at the injector for single charge operation as well as combined working points for

  4. Bunch coalescing in the Fermilab Main Ring

    International Nuclear Information System (INIS)

    Wildman, D.; Martin, P.; Meisner, K.; Miller, H.W.

    1987-01-01

    A new RF system has been installed in the Fermilab Main Ring to coalesce up to 13 individual bunches of protons or antiprotons into a single high-intensity bunch. The coalescing process consists of adiabatically reducing the h=1113 Main Ring RF voltage from 1 MV to less than 1 kV, capturing the debunched beam in a linearized h=53 and h=106 bucket, rotating for a quarter of a synchrotron oscillation period, and then recapturing the beam in a single h=1113 bucket. The new system is described and the results of recent coalescing experiments are compared with computer-generated particle tracking simulations

  5. Bunch heating by coherent synchrotron radiation

    International Nuclear Information System (INIS)

    Heifets, S.A.; Zolotorev, M.

    1995-10-01

    The authors discuss here effects which define the steady-state rms energy spread of a microbunch in a storage ring. It is implied that the longitudinal microwave instability is controlled by low α lattice. In this case the coherent synchrotron radiation, if exists, may be the main factor defining the bunch temperature. Another effect comes from the fact that a nonlinear momentum compaction of such lattices makes Haissinskii equation not applicable, and the coherent synchrotron radiation may effect not only bunch lengthening but the energy spread as well

  6. Sub-fs electron bunch generation with sub-10-fs bunch arrival-time jitter via bunch slicing in a magnetic chicane

    Directory of Open Access Journals (Sweden)

    J. Zhu

    2016-05-01

    Full Text Available The generation of ultrashort electron bunches with ultrasmall bunch arrival-time jitter is of vital importance for laser-plasma wakefield acceleration with external injection. We study the production of 100-MeV electron bunches with bunch durations of subfemtosecond (fs and bunch arrival-time jitters of less than 10 fs, in an S-band photoinjector by using a weak magnetic chicane with a slit collimator. The beam dynamics inside the chicane is simulated by using two codes with different self-force models. The first code separates the self-force into a three-dimensional (3D quasistatic space-charge model and a one-dimensional coherent synchrotron radiation (CSR model, while the other one starts from the first principle with a so-called 3D sub-bunch method. The simulations indicate that the CSR effect dominates the horizontal emittance growth and the 1D CSR model underestimates the final bunch duration and emittance because of the very large transverse-to-longitudinal aspect ratio of the sub-fs bunch. Particularly, the CSR effect is also strongly affected by the vertical bunch size. Due to the coupling between the horizontal and longitudinal phase spaces, the bunch duration at the entrance of the last dipole magnet of the chicane is still significantly longer than that at the exit of the chicane, which considerably mitigates the impact of space charge and CSR effects on the beam quality. Exploiting this effect, a bunch charge of up to 4.8 pC in a sub-fs bunch could be simulated. In addition, we analytically and numerically investigate the impact of different jitter sources on the bunch arrival-time jitter downstream of the chicane, and define the tolerance budgets assuming realistic values of the stability of the linac for different bunch charges and compression schemes.

  7. Quality Assessment of Soaps Produced from Palm Bunch Ash ...

    African Journals Online (AJOL)

    Quality Assessment of Soaps Produced from Palm Bunch Ash-Derived Alkali and ... Journal of Applied Sciences and Environmental Management ... The remedial process involved subjecting the dried palm bunch matter to total combustion, ...

  8. Short bunch wake potentials for a chain of TESLA cavities

    International Nuclear Information System (INIS)

    Novokhatski, Alexander; Mosnier, Alban

    2014-01-01

    The modification of wake fields from a single cavity to a quasi-periodic structure of cavities is of great concern, especially for applications using very short bunches. We extend our former study (Novokhatski, 1997 [1]). A strong modification of wake fields along a train of cavities was clearly found for bunch lengths lower than 1 mm. In particular, the wakes induced by the bunch, as it proceeds down the successive cavities, decrease in amplitude and become more linear around the bunch center, with a profile very close to the integral of the charge density. The loss factor, decreasing also with the number of cells, becomes independent of bunch length for very short bunches and tends asymptotically to a finite value. This nice behavior of wake fields for short bunches presents good opportunity for application of very short bunches in Linear Colliders and X-ray Free Electron Lasers

  9. Theory of coherent transition radiation generated by ellipsoidal electron bunches

    NARCIS (Netherlands)

    Root, op 't W.P.E.M.; Smorenburg, P.W.; Oudheusden, van T.; Wiel, van der M.J.; Luiten, O.J.

    2007-01-01

    We present the theory of coherent transition radiation (CTR) generated by ellipsoidal electron bunches. We calculate analytical expressions for the electric field spectrum, the power spectrum, and the temporal electric field of CTR, generated by cylindrically symmetric ellipsoidal electron bunches

  10. Luminosity geometric reduction factor from colliding bunches with different lengths

    Energy Technology Data Exchange (ETDEWEB)

    Verdu-Andres, S. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2017-09-29

    In the interaction point of the future electron-Ion collider eRHIC, the electron beam bunches are at least one order of magnitude shorter than the proton beam bunches. With the introduction of a crossing angle, the actual number of collisions resulting from the bunch collision gets reduced. Here we derive the expression for the luminosity geometric reduction factor when the bunches of the two incoming beams are not equal.

  11. The Case: Bunche-Da Vinci Learning Partnership Academy

    Science.gov (United States)

    Eisenberg, Nicole; Winters, Lynn; Alkin, Marvin C.

    2005-01-01

    The Bunche-Da Vinci case described in this article presents a situation at Bunche Elementary School that four theorists were asked to address in their evaluation designs (see EJ791771, EJ719772, EJ791773, and EJ792694). The Bunche-Da Vinci Learning Partnership Academy, an elementary school located between an urban port city and a historically…

  12. Interaction of ultrarelativistic electron and proton bunches with dense plasmas

    CERN Document Server

    Rukhadze, A A

    2012-01-01

    Here we discuss the possibility of employment of ultrarelativistic electron and proton bunches for generation of high plasma wakefields in dense plasmas due to the Cherenkov resonance plasma-bunch interaction. We estimate the maximum amplitude of such a wake and minimum system length at which the maximum amplitude can be generated at the given bunch parameters.

  13. The SPS Individual Bunch Measurement System

    CERN Document Server

    Guerrero, A; Jones, R; Savioz, J J

    2001-01-01

    The Individual Bunch Measurement System (IBMS) allows the intensity of each bunch in an LHC batch to be the measured both in the PS to SPS transfer lines and in the SPS ring itself. The method is vased on measuring the peak and valley of the analogue signal supplied by a Fast Beam Current Transformer at a frequency of 40 MHz. A 12 bit acquisition system is required to obtain a 1% resolution for the intensity range of 5X10`9 to 1.7X10`11 protons per bunch, corresponding to the pilot and ultimate LHC bunch intensities. The acquisition selection and external trigger adjustment system is driven by the 200MHz RF, which is distributed using a single-mode fibre-optic link. A local oscilloscope, controlled via a GPIB interface, allows the remote adjustment of the timing signals. The low-level software consists of a real-time task and a communication server run on a VME Power PC, which is accessed using a graphical user interface. This paper describes the system as a whole and presents some recent uses and results fro...

  14. Single bunch stability in the ESRF

    International Nuclear Information System (INIS)

    Farvacque, L.

    1990-01-01

    The longitudinal wake potential/impedance and bunch lengthening/stability in ESRF were studied. A cylindrical approximation of individual components of the vacuum chamber were studied. The results are wake potential and loss parameters. Measurements are necessary when the cylindrical approximation is not realistic. The coaxial wire method which is used gives a wake potential that can be substituted for the computed wake in the analysis. A measurement bench is presently being tested at ESRF. Wake potentials (computed or measured) are added before modeling or approximation is made. The impedance model used is the broad-band resonator model. Equations are derived for the longitudinal potential well. The bunch shape can be estimated knowing the first moments of the line density function. Mode coupling cannot explain the turbulent instability threshold. The threshold has then to be estimated by crude assumptions on potential well or bunch shape distortions. In the ESRF case, this threshold corresponds to a value of asymmetry s (th) = 0.6. Above the threshold the bunch lengthens with this constant asymmetry value

  15. Introduction to impedance for short relativistic bunches

    International Nuclear Information System (INIS)

    Morton, P.L.

    1993-02-01

    The purpose of this paper is to introduce the concept of impedance to calculate the wake field forces left behind by a short bunch which travels at relativistic speed through a structure with discontinuities. We will try to be as intuitive as possible and leave the more rigorous derivations to the second paper on this subject by J. Wang

  16. CERN: The best of the bunch

    International Nuclear Information System (INIS)

    Gagliardi, F.

    1992-01-01

    As other factors governing the electron-positron collision rate in CERN's LEP 27-kilometre storage ring reach their limit, one way of coaxing the collision rate higher is to increase the number of bunches stored in the ring

  17. submitter Measurements on a 20-layer 12.5 kV prototype inductive adder for the CLIC DR kickers

    CERN Document Server

    Holma, J

    2018-01-01

    The CLIC study is investigating the technical feasibility of an electron-positron collider with high luminosity and a nominal centre-of-mass energy of 3 TeV. The predamping rings and damping rings (DRs) will produce ultra-low emittance beam with high bunch charge. To avoid beam emittance increase, the DR kicker systems must provide extremely stable field pulses during injection and extraction of bunches. The DR extraction kicker system consists of a stripline kicker and two pulse modulators. The present specification for the modulators calls for pulses with 160 ns or 900 ns flat-top duration of nominally ±12.5 kV and 305 A, with ripple of not more than ±0.02% (±2.5 V). In addition, there is a proposal to use the same modulators and striplines for dumping the beam, with ±17.5 kV stripline pulse voltage. An inductive adder is a very promising approach to meeting the CLIC DR extraction kicker specifications because analogue modulation methods can be applied to adjust the shape of the flat-top of the output w...

  18. Ion motion in the wake driven by long particle bunches in plasmas

    International Nuclear Information System (INIS)

    Vieira, J.; Silva, L. O.; Fonseca, R. A.; Mori, W. B.

    2014-01-01

    We explore the role of the background plasma ion motion in self-modulated plasma wakefield accelerators. We employ Dawson's plasma sheet model to derive expressions for the transverse plasma electric field and ponderomotive force in the narrow bunch limit. We use these results to determine the on-set of the ion dynamics and demonstrate that the ion motion could occur in self-modulated plasma wakefield accelerators. Simulations show the motion of the plasma ions can lead to the early suppression of the self-modulation instability and of the accelerating fields. The background plasma ion motion can nevertheless be fully mitigated by using plasmas with heavier plasmas

  19. Preliminary Design of an Inductive Adder for CLIC Damping Rings

    CERN Document Server

    Holma, J

    2011-01-01

    The Compact Linear Collider (CLIC) study is exploring the scheme for an electron-positron collider with high luminosity and a nominal centre-of-mass energy of 3 TeV. The CLIC damping rings will produce ultra-low emittance beam, with high bunch charge, necessary for the luminosity performance of the collider. To limit the beam emittance blow-up due to oscillations, the pulse power modulators for the damping rings kickers must provide extremely flat, high-voltage, pulses: specifications call for a 160 ns duration flattop of 12.5 kV, 250 A, with a combined ripple and droop of not more than ±0.02 %. A solid-state modulator, the inductive adder, is a very promising approach to meeting the demanding specifications; this topology allows the use of both digital and analogue modulation. To effectively use modulation techniques to achieve such low ripple and droop requires an in-depth knowledge of the behaviour of the solid-state switching components and their gate drivers, as well as a good understanding of the overa...

  20. Poincaré plot indexes of heart rate variability detect dynamic autonomic modulation during general anesthesia induction.

    Science.gov (United States)

    Hsu, Che-Hao; Tsai, Ming-Ya; Huang, Go-Shine; Lin, Tso-Chou; Chen, Kuen-Pao; Ho, Shung-Tai; Shyu, Liang-Yu; Li, Chi-Yuan

    2012-03-01

    Beat-to-beat heart rate variability (HRV) is caused by the fluctuating balance of sympathetic and parasympathetic tone. The Poincaré plot has been used to evaluate HRV. In this study, we validate that this new method may qualitatively and quantitatively assess the sympathovagal fluctuation in patients during induction of anesthesia with sevoflurane. Twenty-eight young patients were allocated for the study. The patients received a tilt test and on the next day they sustained anesthesia induced with inhaled anesthetics. Electrocardiography signals from the patients were relayed to an analogue-digital converter. The Poincaré plot is quantified by measuring SD1, SD2, and SD1/SD2. Power spectral analyses were performed and LF, HF and HF/LF were calculated. The LF power and the SD2 of the Poincaré plot increased while subjects were tilt-up from the supine position. Additionally, a significant correlation were found between LF and SD2, HF and SD1 (p plot respectively. However, the LF, SD2 and LF/HF increased; the HF, SD1 and SD1/SD2 ratio decreased after intubation stimulation. Poincaré plot and power spectral analysis of HRV during tilt test and sevoflurane induction significantly correlate. Poincaré plot analysis is easier and more sensitive at evaluating the sympathovagal balance and observing the beat-to-beat HRV. Copyright © 2012. Published by Elsevier B.V.

  1. Controlling multi-bunches by a fast phase switching

    International Nuclear Information System (INIS)

    Decker, F.J.; Jobe, R.K.; Merminga, N.; Thompson, K.A.

    1990-09-01

    In linear accelerators with two or more bunches the beam loading of one bunch will influence the energy and energy spread the following bunches. This can be corrected by quickly changing the phase of a traveling wave-structure, so that each bunch receives a slightly different net phase. At the SLAC Linear Collider (SLC) three bunches, two (e + ,e - ) for the high energy collisions and one (e - -scavenger) for producing positrons should sit at different phases, due to their different tasks. The two e - -bunches are extracted from the damping ring at the same cycle time about 60 ns apart. Fast phase switching of the RF to the bunch length compressor in the Ring-To-Linac (RTL) section can produce the necessary advance of the scavenger bunch (about 6 degree in phase). This allows a low energy spread of this third bunch at the e + -production region at 2/3 of the linac length, while the other bunches are not influenced. The principles and possible other applications of this fast phase switching as using it for multi-bunches, as well as the experimental layout for the actual RTL compressor are presented

  2. Femtosecond electron-bunch dynamics in laser wakefields and vacuum

    Directory of Open Access Journals (Sweden)

    A. G. Khachatryan

    2007-12-01

    Full Text Available Recent advances in laser wakefield acceleration demonstrated the generation of extremely short (with a duration of a few femtoseconds relativistic electron bunches with relatively low (of the order of couple of percent energy spread. In this article we study the dynamics of such bunches in drift space (vacuum and in channel-guided laser wakefields. Analytical solutions were found for the transverse coordinate of an electron and for the bunch envelope in the wakefield in the case of arbitrary change in the energy. Our results show strong bunch dynamics already on a millimeter scale propagation distance both in plasma and in vacuum. When the bunch propagates in vacuum, its transverse sizes grow considerably; the same is observed for the normalized bunch emittance that worsens the focusability of the bunch. A scheme of two-stage laser wakefield accelerator with small drift space between the stages is proposed. It is found that fast longitudinal betatron phase mixing occurs in a femtosecond bunch when it propagates along the wakefield axis. When bunch propagates off axis, strong bunch decoherence and fast emittance degradation due to the finite bunch length was observed.

  3. Feasibility Study of Moderately Accelerated Intensity-Modulated Radiotherapy Plus Concurrent Weekly Cisplatin After Induction Chemotherapy in Locally Advanced Head-and Neck Cancer

    International Nuclear Information System (INIS)

    Morganti, Alessio G.; Mignogna, Samantha; Deodato, Francesco; Massaccesi, Mariangela; Cilla, Savino; Calista, Franco; Serafini, Giovanni; Digesu, Cinzia; Macchia, Gabriella; Picardi, Vincenzo; Caravatta, Luciana; Di Lullo, Liberato; Giglio, Gianfranco; Sallustio, Giuseppina; Piermattei, Angelo

    2011-01-01

    Purpose: To evaluate the feasibility and efficacy of moderately accelerated intensity-modulated radiation therapy (IMRT) along with weekly cisplatin, after induction chemotherapy, in patients with locally advanced unresectable head and neck cancer (HNC). Methods and Materials: Patients with Stage III or IV locally advanced HNC, without progressive disease after three courses of induction chemotherapy, received concurrent chemo-IMRT (weekly cisplatin 30 mg/m 2 plus simultaneous integrated boost IMRT). A total of 67.5 Gy in 30 fractions were delivered to primary tumor and involved nodes, 60 Gy in 30 fractions to high-risk nodal areas, and 55.5 Gy in 30 fractions to low-risk nodal areas. Results: In all, 36 patients (median age, 56 years) with International Union Against Cancer (UICC) Stage III (n = 5) and IV (n = 31) were included. Of the 36 patients, 17 had received CF (cisplatin and 5-fluorouracil (CF) and 19 had received docetaxel cisplatin and 5-fluorouracil (DCF). During concurrent chemoradiation, 11 of 36 patients (30.5%) experienced Grade III mucositis (CF, 47%; DCF, 15%; p < 0.04). Grade III pharyngeal-esophageal toxicity was observed in 5 of 19 patients (26.3%; CF, 0.0%; DCF, 26.3%; p = 0.02). Two patients died of complications (5.5%). After chemoradiation, the complete response rate was 63.8%. Two-year local control was 88.7%. Two-year progression free survival and overall survival were 74.5% and 60.9%, respectively. Conclusions: In our experience, a moderately accelerated chemo-IMRT was feasible after induction chemotherapy. However, a noteworthy early death rate of 5.5% was observed. Intensive supportive care strategies should be defined to better manage radiation-induced toxic effects. Longer follow-up is required to determine the incidence of late radiation toxicities and tumor control rates.

  4. The response of early neural genes to FGF signaling or inhibition of BMP indicate the absence of a conserved neural induction module

    Directory of Open Access Journals (Sweden)

    Rogers Crystal D

    2011-12-01

    Full Text Available Abstract Background The molecular mechanism that initiates the formation of the vertebrate central nervous system has long been debated. Studies in Xenopus and mouse demonstrate that inhibition of BMP signaling is sufficient to induce neural tissue in explants or ES cells respectively, whereas studies in chick argue that instructive FGF signaling is also required for the expression of neural genes. Although additional signals may be involved in neural induction and patterning, here we focus on the roles of BMP inhibition and FGF8a. Results To address the question of necessity and sufficiency of BMP inhibition and FGF signaling, we compared the temporal expression of the five earliest genes expressed in the neuroectoderm and determined their requirements for induction at the onset of neural plate formation in Xenopus. Our results demonstrate that the onset and peak of expression of the genes vary and that they have different regulatory requirements and are therefore unlikely to share a conserved neural induction regulatory module. Even though all require inhibition of BMP for expression, some also require FGF signaling; expression of the early-onset pan-neural genes sox2 and foxd5α requires FGF signaling while other early genes, sox3, geminin and zicr1 are induced by BMP inhibition alone. Conclusions We demonstrate that BMP inhibition and FGF signaling induce neural genes independently of each other. Together our data indicate that although the spatiotemporal expression patterns of early neural genes are similar, the mechanisms involved in their expression are distinct and there are different signaling requirements for the expression of each gene.

  5. Induction chemotherapy with nedaplatin with 5-FU followed by intensity-modulated radiotherapy concurrent with chemotherapy for locoregionally advanced nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    Zheng Jijun; Wang Ge; Yang, G.Y.

    2010-01-01

    This Phase II study was conducted to evaluate the activity and feasibility of a regimen of nedaplatin and 5-fluorouracil as induction chemotherapy, followed by intensity-modulated radiotherapy concurrent with chemotherapy in patients with locoregionally advanced nasopharyngeal carcinoma. Patients received neoadjuvant chemotherapy comprised two cycles of 5-fluorouracil at 700 mg/m 2 /day administered on days 1-4 as continuous intravenous infusion and nedaplatin (100 mg/m 2 administered intravenous (i.v.) over 2 h) given after the administration of 5-fluorouracil on day 1, repeated every 3 weeks, followed by intensity-modulated radiotherapy concurrent with nedaplatin. During intensity-modulated radiotherapy, nedaplatin was administered at a dose of 100 mg/m 2 intravenous infusion on days 1, 22 and 43, given -60 min before radiation. Fifty-nine (95.8%) of the 60 patients were assessable for response. Thirty-eight cases of complete response and 14 cases of partial response were confirmed after completion of chemoradiation, with the objective response rate of 86.7% (95% confidence interval (CI), 78.1-95.3%). The median follow-up period was 48 months (range, 30-62 months). The 3-year progression-free survival and overall survival were 75.0% (95% CI, 63.0-87.0%) and 85.5% (95% CI, 75.9-95.1%). No patient showed Grade 3 or higher renal dysfunction. The most commonly observed late effect was xerostomia, but the severity diminished over time, and the detectable xerostomia at 24 months was 10.2%. There were no treatment-related deaths during this study. Neoadjuvant chemotherapy with nedaplatin and 5-fluorouracil followed by concomitant nedaplatin and intensity-modulated radiotherapy is an effective and safe treatment for Southern China patients affected by locoregionally advanced nasopharyngeal carcinoma. (author)

  6. Time-dependent two-temperature chemically non-equilibrium modelling of high-power Ar-N2 pulse-modulated inductively coupled plasmas at atmospheric pressure

    International Nuclear Information System (INIS)

    Tanaka, Yasunori

    2006-01-01

    A time-dependent, two-dimensional, two-temperature and chemical non-equilibrium model was developed for high-power Ar-N 2 pulse-modulated inductively coupled plasmas (PMICPs) at atmospheric pressure. The high-power PMICP is a new technique for sustaining high-power induction plasmas. It can control the plasma temperature and radical densities in the time domain. The PMICP promotes non-equilibrium effects by a sudden application of electric field, even in the high-power density plasmas. The developed model accounts separately for the time-dependent energy conservation equations of electrons and heavy particles. This model also considers reaction heat effects and energy transfer between electrons and heavy particles as well as enthalpy flow resulting from diffusion caused by the particle density gradient. Chemical non-equilibrium effects are also taken into account by solving time-dependent mass conservation equations for each particle, considering diffusion, convection and net production terms resulting from 30 chemical reactions. Transport and thermodynamic properties of Ar-N 2 plasmas are calculated self-consistently using the first order approximation of the Chapman-Enskog method at each position and iteration using the local particle composition, heavy particle temperature and electron temperature. This model is useful to discuss time evolution in temperature, gas flow fields and distribution of chemical species

  7. Globular adiponectin protects rat hepatocytes against acetaminophen-induced cell death via modulation of the inflammasome activation and ER stress: Critical role of autophagy induction.

    Science.gov (United States)

    Kim, Eun Hye; Park, Pil-Hoon

    2018-05-24

    Acetaminophen (APAP) overdose treatment causes severe liver injury. Adiponectin, a hormone predominantly produced by adipose tissue, exhibits protective effects against APAP-induced hepatotoxicity. However, the underlying mechanisms are not clearly understood. In the present study, we examined the protective effect of globular adiponectin (gAcrp) on APAP-induced hepatocyte death and its underlying mechanisms. We found that APAP (2 mM)-induced hepatocyte death was prevented by inhibition of the inflammasome. In addition, treatment with gAcrp (0.5 and 1 μg/ml) inhibited APAP-induced activation of the inflammasome, judged by suppression of interleukin-1β maturation, caspase-1 activation, and apoptosis-associated speck-like protein (ASC) speck formation, suggesting that protective effects of gAcrp against APAP-induced hepatocyte death is mediated via modulation of the inflammasome. APAP also induced ER stress and treatment with tauroursodeoxycholic acid (TUDCA), an ER chaperone and inhibitor of ER stress, abolished APAP-induced inflammasomes activation, implying that ER stress acts as signaling event leading to the inflammasome activation in hepatocytes stimulated with APAP. Moreover, gAcrp significantly suppressed APAP-induced expression of ER stress marker genes. Finally, the modulatory effects of gAcrp on ER stress and inflammasomes activation were abrogated by treatment with autophagy inhibitors, while an autophagy inducer (rapamycin) suppressed APAP-elicited ER stress, demonstrating that autophagy induction plays a crucial role in the suppression of APAP-induced inflammasome activation and ER stress by gAcrp. Taken together, these results indicate that gAcrp protects hepatocytes against APAP-induced cell death by modulating ER stress and the inflammasome activation, at least in part, via autophagy induction. Copyright © 2018. Published by Elsevier Inc.

  8. Long-range functional interactions of anterior insula and medial frontal cortex are differently modulated by visuospatial and inductive reasoning tasks.

    Science.gov (United States)

    Ebisch, Sjoerd J H; Mantini, Dante; Romanelli, Roberta; Tommasi, Marco; Perrucci, Mauro G; Romani, Gian Luca; Colom, Roberto; Saggino, Aristide

    2013-09-01

    The brain is organized into functionally specific networks as characterized by intrinsic functional relationships within discrete sets of brain regions. However, it is poorly understood whether such functional networks are dynamically organized according to specific task-states. The anterior insular cortex (aIC)-dorsal anterior cingulate cortex (dACC)/medial frontal cortex (mFC) network has been proposed to play a central role in human cognitive abilities. The present functional magnetic resonance imaging (fMRI) study aimed at testing whether functional interactions of the aIC-dACC/mFC network in terms of temporally correlated patterns of neural activity across brain regions are dynamically modulated by transitory, ongoing task demands. For this purpose, functional interactions of the aIC-dACC/mFC network are compared during two distinguishable fluid reasoning tasks, Visualization and Induction. The results show an increased functional coupling of bilateral aIC with visual cortices in the occipital lobe during the Visualization task, whereas coupling of mFC with right anterior frontal cortex was enhanced during the Induction task. These task-specific modulations of functional interactions likely reflect ability related neural processing. Furthermore, functional connectivity strength between right aIC and right dACC/mFC reliably predicts general task performance. The findings suggest that the analysis of long-range functional interactions may provide complementary information about brain-behavior relationships. On the basis of our results, it is proposed that the aIC-dACC/mFC network contributes to the integration of task-common and task-specific information based on its within-network as well as its between-network dynamic functional interactions. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. A COMPARATIVE ANALYSIS OF PROCESSES IN AN INDEPENDENT GENERATOR WITH A NONCONTACT CASCADE THREE-PHASE MODULATED EXCITER VIA A STAR-CONNECTED CIRCUIT UNDER ACTIVE-INDUCTIVE LOADING

    Directory of Open Access Journals (Sweden)

    K.M. Vasyliv

    2013-02-01

    Full Text Available By means of mathematical experiment, the author investigates electromagnetic and electromechanical processes in an independent electric power supply system based on an asynchronized generator with a three-phase modulated exciter. The processes are analyzed to specify the working capacity of the power supply system during its operation under active-inductive loading. Regularities of the electromagnetic and electromechanical processes behavior versus load intensity and the modulator scheme are identified.

  10. Single bunch instabilities in an SSC

    International Nuclear Information System (INIS)

    Ruth, R.D.

    1984-01-01

    In this note coherent instability thresholds are estimated for the SSC and discuss some of the subsequent design restrictions. The various instabilities are set out in a block diagram with the essential features of each. The assumption is made that long wavelength coupled bunch effects can be cured effectively by a feedback system (both longitudinal and transverse) and that the impedance of the feedback system is such as to cancel that of the environment (at low frequency). Alternatively, the long wake field is assumed to be exactly canceled, on the average, by a feedback wake field. This leaves only single bunch effects. Thresholds for fast-blowup are discussed both in the longitudinal and transverse and the transverse mode coupling instability more familiar in electron/positron storage rings is covered. The impedances considered are a broadband impedance and the resistive wall impedance

  11. Halo formation in three-dimensional bunches

    International Nuclear Information System (INIS)

    Gluckstern, R.L.; Fedotov, A.V.; Kurennoy, S.; Ryne, R.

    1998-01-01

    We have constructed, analytically and numerically, a class of self-consistent six-dimensional (6D) phase space stationary distributions. Stationary distributions allow us to study the halo development mechanism without it being obscured by beam redistribution and its effect on halo formation. The beam is then mismatched longitudinally and/or transversely, and we explore the formation of longitudinal and transverse halos in 3D axisymmetric beam bunches. We find that the longitudinal halo forms first for comparable longitudinal and transverse mismatches because the longitudinal tune depression is more severe than the transverse one for elongated bunches. Of particular importance is the result that, due to the coupling between longitudinal and transverse motion, a longitudinal or transverse halo is observed for a mismatch less than 10% if the mismatch in the other plane is large. copyright 1998 The American Physical Society

  12. Extremely short relativistic-electron-bunch generation in the laser wakefield via novel bunch injection scheme

    Directory of Open Access Journals (Sweden)

    A. G. Khachatryan

    2004-12-01

    Full Text Available Recently a new electron-bunch injection scheme for the laser wakefield accelerator has been proposed [JETP Lett. 74, 371 (2001JTPLA20021-364010.1134/1.1427124; Phys. Rev. E 65, 046504 (2002PLEEE81063-651X10.1103/PhysRevE.65.046504]. In this scheme, a low energy electron bunch, sent in a plasma channel just before a high-intensity laser pulse, is trapped in the laser wakefield, considerably compressed and accelerated to an ultrarelativistic energy. In this paper we show the possibility of the generation of an extremely short (on the order of 1   μm long or a few femtoseconds in duration relativistic-electron-bunch by this mechanism. The initial electron bunch, which can be generated, for example, by a laser-driven photocathode rf gun, should have an energy of a few hundred keVs to a few MeVs, a duration in the picosecond range or less and a relatively low concentration. The trapping conditions and parameters of an accelerated bunch are investigated. The laser pulse dynamics as well as a possible experimental setup for the demonstration of the injection scheme are also considered.

  13. Bunch Length Measurements using Coherent Radiation

    CERN Document Server

    Ischebeck, Rasmus; Barnes, Christopher; Blumenfeld, Ian; Clayton, Chris; Decker, Franz Josef; Deng, Suzhi; Hogan, Mark; Huang Cheng Kun; Iverson, Richard; Johnson, Devon K; Krejcik, Patrick; Lu, Wei; Marsh, Kenneth; Oz, Erdem; Siemann, Robert; Walz, Dieter

    2005-01-01

    The accelerating field that can be obtained in a beam-driven plasma wakefield accelerator depends on the current of the electron beam that excites the wake. In the E-167 experiment, a peak current above 10kA will be delivered at a particle energy of 28GeV. The bunch has a length of a few ten micrometers and several methods are used to measure its longitudinal profile. Among these, autocorrelation of coherent transition radiation (CTR) is employed. The beam passes a thin metallic foil, where it emits transition radiation. For wavelengths greater than the bunch length, this transition radiation is emitted coherently. This amplifies the long-wavelength part of the spectrum. A scanning Michelson interferometer is used to autocorrelate the CTR. However, this method requires the contribution of many bunches to build an autocorrelation trace. The measurement is influenced by the transmission characteristics of the vacuum window and beam splitter. We present here an analysis of materials, as well as possible layouts ...

  14. Centrally located GLP-1 receptors modulate gastric slow waves and cardiovascular function in ferrets consistent with the induction of nausea.

    Science.gov (United States)

    Lu, Zengbing; Yeung, Chi-Kong; Lin, Ge; Yew, David T W; Andrews, P L R; Rudd, John A

    2017-10-01

    Glucagon-like peptide-1 (GLP-1) receptor agonists are indicated for the treatment of Type 2 diabetes and obesity, but can cause nausea and emesis in some patients. GLP-1 receptors are distributed widely in the brain, where they contribute to mechanisms of emesis, reduced appetite and aversion, but it is not known if these centrally located receptors also contribute to a modulation of gastric slow wave activity, which is linked causally to nausea. Our aim was to investigate the potential of the GLP-1 receptor agonist, exendin-4, administered into the 3rd ventricle to modulate emesis, feeding and gastric slow wave activity. Thermoregulation and cardiovascular parameters were also monitored, as they are disturbed during nausea. Ferrets were used as common laboratory rodents do not have an emetic reflex. A guide cannula was implanted into the 3rd ventricle for delivering a previously established dose of exendin-4 (10nmol), which had been shown to induce emesis and behaviours indicative of 'nausea'. Radiotelemetry recorded gastric myoelectric activity (GMA; slow waves), blood pressure and heart rate variability (HRV), and core temperature; food intake and behaviour were also assessed. Exendin-4 (10nmol, i.c.v.) decreased the dominant frequency of GMA, with an associated increase in the percentage of bradygastric power (lasting ~4h). Food intake was inhibited in all animals, with 63% exhibiting emesis. Exendin-4 also increased blood pressure (lasting ~24h) and heart rate (lasting ~7h), decreased HRV (lasting ~24h), and caused transient hyperthermia. None of the above parameters were emesis-dependent. The present study shows for the first time that gastric slow waves may be modulated by GLP-1 receptors in the brain through mechanisms that appear independent from emesis. Taken together with a reduction in HRV, the findings are consistent with changes associated with the occurrence of nausea in humans. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Comparative Study of Modulation-Based Individual Inverter Techniques for Direct and Inverse by using Star-Connection Induction Motor in Extra Low Voltage Application

    Directory of Open Access Journals (Sweden)

    Ardhia Wishnuprakasa

    2016-12-01

    Full Text Available In this study, the IEEE 519 Standard as a basis benchmarking for voltage (THDV and current (THDI in draft performance. Comparative Study based onthree-techniques of 2-Level Converter (2LC by using a Star-Connection Induction Motor (Y-CIM in ExtraLow Voltage (ELV Configuration.For the detail explanation, a primary inverter as Direct-Inverterby PWMdirect (PWM degreesand asecondary inverter as Inverse-Inverterby PWMinverse(PWM + PI degrees. It tends a modified algorithm,for eachof SPWM in six rules, and FHIPWM in 5th harmonics Injectedin standard modulation as the purpose for the Open-Ends of Pre-Dual Inverter in Decoupled SPWM for twelve rules, and Decoupled FHIPWM in combination of 5th harmonics Injectedin combination of two-standard-modulation. Those techniques are the purpose of two-inverter combination, which namelythe Equal Direct-Inverse (EDI algorithmproduct of prototyping in similarities. The observation is restricted in voltage scope between Simulation by using Power Simulator (PSIMand Application by using Microcontroller ARM STM32F4 Discovery.

  16. Induction of Osmoadaptive Mechanisms and Modulation of Cellular Physiology Help Bacillus licheniformis Strain SSA 61 Adapt to Salt Stress

    Energy Technology Data Exchange (ETDEWEB)

    Paul, Sangeeta; Aggarwal, Chetana; Thakur, Jyoti Kumar; Bandeppa, G. S.; Khan, Md. Aslam; Pearson, Lauren M.; Babnigg, Gyorgy; Giometti, Carol S.; Joachimiak, Andrzej

    2015-01-06

    Bacillus licheniformis strain SSA 61, originally isolated from Sambhar salt lake, was observed to grow even in the presence of 25 % salt stress. Osmoadaptive mechanisms of this halotolerant B. licheniformis strain SSA 61, for long-term survival and growth under salt stress, were determined. Proline was the preferentially accumulated compatible osmolyte. There was also increased accumulation of antioxidants ascorbic acid and glutathione. Among the different antioxidative enzymes assayed, superoxide dismutase played the most crucial role in defense against salt-induced stress in the organism. Adaptation to stress by the organism involved modulation of cellular physiology at various levels. There was enhanced expression of known proteins playing essential roles in stress adaptation, such as chaperones DnaK and GroEL, and general stress protein YfkM and polynucleotide phosphorylase/polyadenylase. Proteins involved in amino acid biosynthetic pathway, ribosome structure, and peptide elongation were also overexpressed. Salt stress-induced modulation of expression of enzymes involved in carbon metabolism was observed. There was up-regulation of a number of enzymes involved in generation of NADH and NADPH, indicating increased cellular demand for both energy and reducing power.

  17. Direct electrical stimulation using a battery-operated device for induction and modulation of colonic contractions in pigs.

    Science.gov (United States)

    Bertschi, Mattia; Schlageter, Vincent; Vesin, Jean-Marc; Aellen, Steve; Peloponissios, Nicolas; D'Ambrogio, Aris; Wiesel, Paul Herman; Givel, Jean-Claude; Kucera, Pavel; Virag, Nathalie

    2010-07-01

    Direct electrical stimulation of the colon offers a promising approach for the induction of propulsive colonic contractions by using an implantable device. The objective of this study was to assess the feasibility to induce colonic contractions using a commercially available battery-operated stimulator (maximum pulse width of 1 ms and maximum amplitude of 10 V). Three pairs of pacing electrodes were inserted into the cecal seromuscular layer of anesthetized pigs. During a first set of in vivo experiments conducted on six animals, a pacing protocol leading to cecum contractions was determined: stimulation bursts with 1 ms pulse width, 10 V amplitude (7-15 mA), 120 Hz frequency, and 30-s burst duration, repeated every 2-5 min. In a second testing phase, an evaluation of the pacing protocol was performed in four animals (120 stimulation bursts in total). By using the battery-operated stimulator, contractions of the cecum and movement of contents could be induced in 92% of all stimulations. A cecal shortening of about 30% and an average intraluminal pressure increase of 10.0 +/- 6.0 mmHg were observed.

  18. Relational complexity modulates activity in the prefrontal cortex during numerical inductive reasoning: an fMRI study.

    Science.gov (United States)

    Feng, Xiao; Peng, Li; Chang-Quan, Long; Yi, Lei; Hong, Li

    2014-09-01

    Most previous studies investigating relational reasoning have used visuo-spatial materials. This fMRI study aimed to determine how relational complexity affects brain activity during inductive reasoning, using numerical materials. Three numerical relational levels of the number series completion task were adopted for use: 0-relational (e.g., "23 23 23"), 1-relational ("32 30 28") and 2-relational ("12 13 15") problems. The fMRI results revealed that the bilateral dorsolateral prefrontal cortex (DLPFC) showed enhanced activity associated with relational complexity. Bilateral inferior parietal lobule (IPL) activity was greater during the 1- and 2-relational level problems than during the 0-relational level problems. In addition, the left fronto-polar cortex (FPC) showed selective activity during the 2-relational level problems. The bilateral DLPFC may be involved in the process of hypothesis generation, whereas the bilateral IPL may be sensitive to calculation demands. Moreover, the sensitivity of the left FPC to the multiple relational problems may be related to the integration of numerical relations. The present study extends our knowledge of the prefrontal activity pattern underlying numerical relational processing. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. A longitudinal bunch monitoring system using LabVIEW reg-sign and high-speed oscilloscopes

    International Nuclear Information System (INIS)

    Barsotti, E.L.

    1994-10-01

    A new longitudinal bunch monitoring system has been installed at Fermilab for the Tevatron and Main Ring. For each machine, a signal from a broadband wall current monitor is sampled and digitized by a high-speed oscilloscope. A Macintosh computer, running LabVIEW-based software, controls the scopes and CAMAC timing modules and analyzes the acquired data. The resulting bunch parameters are used for a variety of purposes, including Tevatron collider luminosity calculation and injection analysis. This paper examines the system in detail

  20. Intensity and bunch length measurement for lepton beam in the injection lines of the SPS and LEP

    CERN Document Server

    Boccard, C; Papis, J P; Vos, L

    1995-01-01

    We describe a system which is used operationally to measure the absolute intensity of single lepton bunches in a beam transfer line. It is based on the detailed knowledge of every single item of a complex measuring chain that comprises a beam coupler on one end and an acquisition system on the other end. This knowledge can be acquired by a well tested theoretical model and careful measurement of the transfer function of each processing module. A precision better than 3 % can be obtained and no external calibration is required. A value for the bunch length can be deduced from a spectral intensity measurement at two well chosen frequencies.

  1. SuperB Bunch-By-Bunch Feedback R&D

    Energy Technology Data Exchange (ETDEWEB)

    Drago, A.; Beretta, M.; /Frascati; Bertsche, K.; Novokhatski, A.; /SLAC; Migliorati, M.; /Rome U.

    2011-08-12

    The SuperB project has the goal to build in Italy, in the Frascati or Tor Vergata area, an asymmetric e{sup +}/e{sup -} Super Flavor Factory to achieve a peak luminosity > 10**36 cm{sup -2} s{sup -1}. The SuperB design is based on collisions with extremely low vertical emittance beams and high beam currents. A source of emittance growth comes from the bunch by bunch feedback systems producing high power correction signals to damp the beams. To limit any undesirable effect, a large R&D program is in progress, partially funded by the INFN Fifth National Scientific Committee through the SFEED (SuperB Feedback) project approved within the 2010 budget. The SuperB project [1] has the goal to build in Italy, in the Frascati or Tor Vergata area, an asymmetric e{sup +}/e{sup -} Super Flavor Factory to achieve a peak luminosity > 10**36 cm{sup -2} s{sup -1}. In the last and current years, the machine layout has been deeply modified, in particular the main rings are now shorter and an option with high currents has been foreseen. In the fig.1 the new SuperB layout is shown. From bunch-by-bunch feedback point of view, the simultaneous presence in the machine parameters, of very low emittance, of the order of 5-10 pm in the vertical plane, and very high currents, at level of 4 Ampere for the Low Energy Ring, asks for designing very carefully the bunch-by-bunch feedback systems. The parameter list is presented in Fig. 2. The bunch-by-bunch feedback design must take care of the risky and exciting challenges proposed in the SuperB specifications, but it should consider also some other important aspects: flexibility in terms of being able to cope to unexpected beam behaviours [2], [3] legacy of previous version experience [4], [5] and internal powerful diagnostics [6] as in the systems previously used in PEP-II and DAFNE [7].

  2. On measuring charged particle bunch duration in linear accelerators

    International Nuclear Information System (INIS)

    Lomize, L.G.; Malykh, N.I.; Khizhnyj, V.I.; Yampol'skij, E.S.

    1977-01-01

    The process of measuring short bunches is simulated by means of cavity resonators in which HF fields are excited by both positive and negative ion bunches flying through them. The simulation is aimed to assess optimum operation of a linear accelerator. A set of bunches of chance form and duration is simulated. Then the simulation of the process of restoring the duration and shape of a bunch according to data obtained from a limited number of resonators is realized. The use of 3-4 resonators tuned to 3, 6, 9 and 12-th harmonics of bunch repetition rate is shown to be sufficient for determining bunch duration with an accuracy of several per cent. When data on harmonic phases is available, one can obtain information on beam asymmetry

  3. A psychophysical study of endogenous analgesia: the role of the conditioning pain in the induction and magnitude of conditioned pain modulation.

    Science.gov (United States)

    Nir, Rony-Reuven; Granovsky, Yelena; Yarnitsky, David; Sprecher, Elliot; Granot, Michal

    2011-05-01

    Endogenous analgesia (EA) can be examined experimentally using a conditioned pain modulation (CPM) paradigm. While noxious conditioning stimulation intensities (CSIs) are mainly used, it has not been fully investigated in the same experimental design whether the experienced conditioning pain level affects CPM responses. The principal goal of the present study was to characterize CPM induction and magnitudes evoked by various conditioning pain levels. Furthermore, we explored associations between conditioning pain reports and CPM responses across various CSIs. Thirty healthy, young, right-handed males were tested with a parallel CPM paradigm. Three different CSIs (hand water-immersion) induced mild, moderate and intense pain levels, rated 12.41 ± 7.85, 31.57 ± 9.56 and 58.1 ± 11.43, respectively (0-100 numerical pain scale) (P < 0.0001). Contact-heat 'test-stimulus' levels were compared before and during conditioning. Within the group, (i) CPM was induced only by the moderate and intense CSIs (Ps ≤ 0.001); (ii) no difference was demonstrated between the magnitudes of these CPM responses. Regression analysis revealed that CPM induction was independent of the perceived conditioning pain level, but associated with the absolute CSI (P < 0.0001). Conditioning pain levels were correlated across all CSIs, as were CPM magnitudes (Ps ≤ 0.01). We conclude that among males, (i) once a CPM response is evoked by a required conditioning pain experience, its magnitude is not further affected by increasing conditioning pain and (ii) CPM magnitudes are inter-correlated, but unrelated to conditioning pain reports. These observations may suggest that CPM responses represent an intrinsic element of an individual's EA processes, which are not significantly affected by the experienced conditioning pain. Copyright © 2010 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved.

  4. Environmental modulation of autoimmune arthritis involves the spontaneous microbial induction of T cell responses to regulatory determinants within heat shock protein 65.

    Science.gov (United States)

    Moudgil, K D; Kim, E; Yun, O J; Chi, H H; Brahn, E; Sercarz, E E

    2001-03-15

    Both genetic and environmental factors are believed to be involved in the induction of autoimmune diseases. Adjuvant arthritis (AA) is inducible in susceptible rat strains by injection of Mycobacterium tuberculosis, and arthritic rats raise T cell responses to the 65-kDa mycobacterial heat-shock protein (Bhsp65). We observed that Fischer 344 (F344) rats raised in a barrier facility (BF-F344) are susceptible to AA, whereas F344 rats maintained in a conventional facility (CV-F344) show significantly reduced incidence and severity of AA, despite responding well to the arthritogenic determinant within Bhsp65. The acquisition of protection from AA can be circumvented if rats are maintained on neomycin/acidified water. Strikingly, naive unimmunized CV-F344 rats but not BF-F344 rats raised T cell responses to Bhsp65 C-terminal determinants (BCTD) (we have previously shown that BCTD are involved in regulation of acute AA in the Lewis rat); however, T cells of naive CV-F344 and BF-F344 gave a comparable level of proliferative response to a mitogen, but no response at all to an irrelevant Ag. Furthermore, adoptive transfer into naive BF-F344 rats of splenic cells of naive CV-F344 rats (restimulated with BCTD in vitro) before induction of AA resulted in a considerably reduced severity of AA. These results suggest that spontaneous (inadvertent) priming of BCTD-reactive T cells, owing to determinant mimicry between Bhsp65 and its homologues in microbial agents in the conventional environment, is involved in modulating the severity of AA in CV-F344 rats. These results have important implications in broadening understanding of the host-microbe interaction in human autoimmune diseases.

  5. Apoptosis Induction of Human Prostate Carcinoma DU145 Cells by Diallyl Disulfide via Modulation of JNK and PI3K/AKT Signaling Pathways

    Directory of Open Access Journals (Sweden)

    Young Hyun Yoo

    2012-11-01

    Full Text Available Diallyl disulfide (DADS, a sulfur compound derived from garlic, has various biological properties, such as anticancer, antiangiogenic and anti-inflammatory effects. However, the mechanisms of action underlying the compound's anticancer activity have not been fully elucidated. In this study, the apoptotic effects of DADS were investigated in DU145 human prostate carcinoma cells. Our results showed that DADS markedly inhibited the growth of the DU145 cells by induction of apoptosis. Apoptosis was accompanied by modulation of Bcl-2 and inhibitor of apoptosis protein (IAP family proteins, depolarization of the mitochondrial membrane potential (MMP, ΔΨm and proteolytic activation of caspases. We also found that the expression of death-receptor 4 (DR4 and Fas ligand (FasL proteins was increased and that the level of intact Bid proteins was down-regulated by DADS. Moreover, treatment with DADS induced phosphorylation of mitogen-activated protein kinases (MAPKs, including extracellular-signal regulating kinase (ERK, p38 MAPK and c-Jun N-terminal kinase (JNK. A specific JNK inhibitor, SP600125, significantly blocked DADS-induced-apoptosis, whereas inhibitors of the ERK (PD98059 and p38 MAPK (SB203580 had no effect. The induction of apoptosis was also accompanied by inactivation of phosphatidylinositol 3-kinase (PI3K/Akt and the PI3K inhibitor LY29004 significantly increased DADS-induced cell death. These findings provide evidence demonstrating that the proapoptotic effect of DADS is mediated through the activation of JNK and the inhibition of the PI3K/Akt signaling pathway in DU145 cells.

  6. Studying p53 family proteins in yeast: Induction of autophagic cell death and modulation by interactors and small molecules

    Energy Technology Data Exchange (ETDEWEB)

    Leão, Mariana; Gomes, Sara; Bessa, Cláudia; Soares, Joana; Raimundo, Liliana [REQUIMTE, Laboratório de Microbiologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira n. 164, 4050-313 Porto (Portugal); Monti, Paola; Fronza, Gilberto [Mutagenesis Unit, Istituto di Ricerca e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino-IST-Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa (Italy); Pereira, Clara [REQUIMTE, Laboratório de Microbiologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira n. 164, 4050-313 Porto (Portugal); Saraiva, Lucília, E-mail: lucilia.saraiva@ff.up.pt [REQUIMTE, Laboratório de Microbiologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira n. 164, 4050-313 Porto (Portugal)

    2015-01-01

    In this work, the yeast Saccharomyces cerevisiae was used to individually study human p53, p63 (full length and truncated forms) and p73. Using this cell system, the effect of these proteins on cell proliferation and death, and the influence of MDM2 and MDMX on their activities were analyzed. When expressed in yeast, wild-type p53, TAp63, ΔNp63 and TAp73 induced growth inhibition associated with S-phase cell cycle arrest. This growth inhibition was accompanied by reactive oxygen species production and autophagic cell death. Furthermore, they stimulated rapamycin-induced autophagy. On the contrary, none of the tested p53 family members induced apoptosis either per se or after apoptotic stimuli. As previously reported for p53, also TAp63, ΔNp63 and TAp73 increased actin expression levels and its depolarization, suggesting that ACT1 is also a p63 and p73 putative yeast target gene. Additionally, MDM2 and MDMX inhibited the activity of all tested p53 family members in yeast, although the effect was weaker on TAp63. Moreover, Nutlin-3a and SJ-172550 were identified as potential inhibitors of the p73 interaction with MDM2 and MDMX, respectively. Altogether, the yeast-based assays herein developed can be envisaged as a simplified cell system to study the involvement of p53 family members in autophagy, the modulation of their activities by specific interactors (MDM2 and MDMX), and the potential of new small molecules to modulate these interactions. - Highlights: • p53, p63 and p73 are individually studied in the yeast S. cerevisiae. • p53 family members induce ROS production, cell cycle arrest and autophagy in yeast. • p53 family members increase actin depolarization and expression levels in yeast. • MDM2 and MDMX inhibit the activity of p53 family members in yeast. • Yeast can be a useful tool to study the biology and drugability of p53, p63 and p73.

  7. Studying p53 family proteins in yeast: Induction of autophagic cell death and modulation by interactors and small molecules

    International Nuclear Information System (INIS)

    Leão, Mariana; Gomes, Sara; Bessa, Cláudia; Soares, Joana; Raimundo, Liliana; Monti, Paola; Fronza, Gilberto; Pereira, Clara; Saraiva, Lucília

    2015-01-01

    In this work, the yeast Saccharomyces cerevisiae was used to individually study human p53, p63 (full length and truncated forms) and p73. Using this cell system, the effect of these proteins on cell proliferation and death, and the influence of MDM2 and MDMX on their activities were analyzed. When expressed in yeast, wild-type p53, TAp63, ΔNp63 and TAp73 induced growth inhibition associated with S-phase cell cycle arrest. This growth inhibition was accompanied by reactive oxygen species production and autophagic cell death. Furthermore, they stimulated rapamycin-induced autophagy. On the contrary, none of the tested p53 family members induced apoptosis either per se or after apoptotic stimuli. As previously reported for p53, also TAp63, ΔNp63 and TAp73 increased actin expression levels and its depolarization, suggesting that ACT1 is also a p63 and p73 putative yeast target gene. Additionally, MDM2 and MDMX inhibited the activity of all tested p53 family members in yeast, although the effect was weaker on TAp63. Moreover, Nutlin-3a and SJ-172550 were identified as potential inhibitors of the p73 interaction with MDM2 and MDMX, respectively. Altogether, the yeast-based assays herein developed can be envisaged as a simplified cell system to study the involvement of p53 family members in autophagy, the modulation of their activities by specific interactors (MDM2 and MDMX), and the potential of new small molecules to modulate these interactions. - Highlights: • p53, p63 and p73 are individually studied in the yeast S. cerevisiae. • p53 family members induce ROS production, cell cycle arrest and autophagy in yeast. • p53 family members increase actin depolarization and expression levels in yeast. • MDM2 and MDMX inhibit the activity of p53 family members in yeast. • Yeast can be a useful tool to study the biology and drugability of p53, p63 and p73

  8. More Options for the NLC Bunch Compressors (LCC-0035)

    International Nuclear Information System (INIS)

    Emma, P.

    2004-01-01

    The present bunch compressor design for the NLC allows control of the final bunch length by way of changes to the horizontal betatron phase advance of the 180 o -turnaround arc. This adjustability requirement significantly constrains the design and cost optimization of the system and excludes the possibility of using permanent magnet quadrupoles in the arc. To relieve this constraint, and to avoid the very strong arc focusing required at the upper limits of the bunch length range, we explore an option of bunch length control using the first compressor stage, with the arc optics fixed

  9. Ply tensile properties of banana stem and banana bunch fibres

    African Journals Online (AJOL)

    2012-03-01

    Mar 1, 2012 ... BANANA BUNCH FIBRES REINFORCED NATURAL RUBBER. COMPOSITE ... National Institute for Interdisciplinary Science and Technology, (NIIST) CSIR Trivandrum, India. ..... Handbook of Ceramics and Composites,. Vol.

  10. Bunch length measurements in the SLC damping ring

    International Nuclear Information System (INIS)

    Decker, F.J.; Limberg, T.; Minty, M.; Ross, M.

    1993-05-01

    The synchrotron light of the SLC damping ring was used to measure the bunch length with a streak camera at different times in the damping cycle. There are bunch length oscillations after injection, different equilibrium length during the cycle due to rf manipulations to avoid microwave instability oscillations, and just before extraction there is a longitudinal phase space rotation (bunch muncher) to shorten the bunch length. Measurements under these different conditions are presented and compared with BPM pulse height signals. Calibration and adjustment issues and the connection of the streak camera to the SLC control system are also discussed

  11. POSITION DETERMINATION OF CLOSELY SPACED BUNCHES USING CAVITY BPMs

    CERN Document Server

    Joshi, N; Cullinan, F; Lyapin, A

    2011-01-01

    Radio Frequency (RF) Cavity Beam Position Monitor (BPM) systems form a major part of precision position measurement diagnostics for linear accelerators with low emittance beams. Using cavity BPMs, a position resolution of less than 100 nm has been demonstrated in single bunch mode operation. In the case of closely spaced bunches, where the decay time of the cavity is comparable to the time separation between bunches, the BPM signal from a bunch is polluted by the signal induced by the previous bunches in the same bunch-train. This paper discusses our ongoing work to develop the methods to extract the position of closely spaced bunches using cavity BPMs. A signal subtraction code is being developed to remove the signal pollution from previous bunches and to determine the individual bunch position. Another code has been developed to simulate the BPM data for the cross check. Performance of the code is studied on the experimental and simulated data. Application of the analysis techniques to the linear colliders,...

  12. HuR/ELAVL1 RNA binding protein modulates interleukin-8 induction by muco-active ribotoxin deoxynivalenol

    International Nuclear Information System (INIS)

    Choi, Hye Jin; Yang, Hyun; Park, Seong Hwan; Moon, Yuseok

    2009-01-01

    HuR/Elav-like RNA binding protein 1 (ELAVL1) positively regulates mRNA stability of AU-rich elements (ARE)-containing transcript such as pro-inflammatory cytokines. Ribotoxic stresses can trigger the production of pro-inflammatory mediators by enhancing mRNA stability and the transcriptional activity. We investigated the effects of ribotoxin deoxynivalenol (DON) on HuR translocation and its involvement in the regulation of the pro-inflammatory interleukin-8 (IL-8) mRNA stability. Exposure to the muco-active DON induced nuclear export of both endogenous and exogenous HuR RNA binding protein in human intestinal epithelial cells. Moreover, the interference with HuR protein production suppressed ribotoxic DON-induced IL-8 secretion and its mRNA stability. Cytoplasmic HuR protein interacted with IL-8 mRNA and the complex stabilization was due to the presence of 3'-untranslated region of the transcript. Partly in terms of IL-8-modulating transcription factors, HuR protein was demonstrated to be positively and negatively associated with DON-induced early growth response gene 1 (EGR-1) and activating transcription factor 3 (ATF3), respectively. HuR was a critical mechanistic link between ribotoxic stress and the pro-inflammatory cytokine production, and may have a broader functional significance with regard to mucosal insults since ribotoxic stress responses are also produced upon interactions with the diverse environment of gut.

  13. High Charge PHIN Photo Injector at CERN with Fast Phase switching within the Bunch Train for Beam Combination

    CERN Document Server

    Csatari Divall, M; Bolzon, B; Bravin, E; Chevallay, E; Dabrowski, A; Doebert, S; Drozdy, A; Fedosseev, V; Hessler, C; Lefevre, T; Livesley, S; Losito, R; Olvegaard, M; Petrarca, M; Rabiller, A N; Egger, D; Mete, O

    2011-01-01

    The high charge PHIN photo-injector was developed within the framework of the European CARE program to provide an alternative to the drive beam thermionic gun in the CTF3 (CLIC Test Facility) at CERN. In PHIN 1908 electron bunches are delivered with bunch spacing of 1.5 GHz and 2.33 nC charge per bunch. Furthermore the drive beam generated by CTF3 requires several fast 180 deg phase-shifts with respect to the 1.5 GHz bunch repetition frequency in order to allow the beam combination scheme developed at CTF3. A total of 8 subtrains, each 140 ns long and shifted in phase with respect to each other, have to be produced with very high phase and amplitude stability. A novel fiber modulator based phase-switching technique developed on the laser system provides this phase-shift between two consecutive pulses much faster and cleaner than the base line scheme, where a thermionic electron gun and sub-harmonic bunching are used. The paper describes the fiber-based switching system and the measurements verifying the schem...

  14. Commissioning of FPGA-based Transverse and Longitudinal Bunch-by-Bunch Feedback System for the TLS

    International Nuclear Information System (INIS)

    Hu, K. H.; Kuo, C. H.; Lau, W. K.; Yeh, M. S.; Hsu, S. Y.; Chou, P. J.; Wang, M. H.; Lee, Demi; Chen, Jenny; Wang, C. J.; Hsu, K. T.; Kobayashi, K.; Nakamura, T.; Dehler, M.

    2006-01-01

    Multi-bunch instabilities deteriorate beam quality, increasing beam emittance, or even causing beam loss in the synchrotron light source. The feedback system is essential to suppress multi-bunch instabilities caused by the impedances of beam ducts, and trapped ions. A new FPGA based transverse and longitudinal bunch-by-bunch feedback system have been commissioned at the Taiwan Light Source recently, A single feedback loop is used to simultaneously suppress the horizontal and the vertical multi-bunch instabilities. Longitudinal instabilities caused by cavity-like structures are suppressed by the longitudinal feedback loop. The same FPGA processor is employed in the transverse feedback and the longitudinal feedback system respectively. Diagnostic memory is included in the system to capture the bunch oscillation signal, which supports various studies

  15. Modulation of DNA damage response and induction of apoptosis mediates synergism between doxorubicin and a new imidazopyridine derivative in breast and lung cancer cells.

    Science.gov (United States)

    El-Awady, Raafat A; Semreen, Mohammad H; Saber-Ayad, Maha M; Cyprian, Farhan; Menon, Varsha; Al-Tel, Taleb H

    2016-01-01

    DNA damage response machinery (DDR) is an attractive target of cancer therapy. Modulation of DDR network may alter the response of cancer cells to DNA damaging anticancer drugs such as doxorubicin. The aim of the present study is to investigate the effects of a newly developed imidazopyridine (IAZP) derivative on the DDR after induction of DNA damage in cancer cells by doxorubicin. Cytotoxicity sulphrhodamine-B assay showed a weak anti-proliferative effect of IAZP alone on six cancer cell lines (MCF7, A549, A549DOX11, HepG2, HeLa and M8) and a normal fibroblast strain. Combination of IAZP with doxorubicin resulted in synergism in lung (A549) and breast (MCF7) cancer cells but neither in the other cancer cell lines nor in normal fibroblasts. Molecular studies revealed that synergism is mediated by modulation of DNA damage response and induction of apoptosis. Using constant-field gel electrophoresis and immunofluorescence detection of γ-H2AX foci, IAZP was shown to inhibit the repair of doxorubicin-induced DNA damage in A549 and MCF7 cells. Immunoblot analysis showed that IAZP suppresses the phosphorylation of the ataxia lelangiectasia and Rad3 related (ATR) protein, which is an important player in the response of cancer cells to chemotherapy-induced DNA damage. Moreover, IAZP augmented the doxorubicin-induced degradation of p21, activation of p53, CDK2, caspase 3/7 and phosphorylation of Rb protein. These effects enhanced doxorubicin-induced apoptosis in both cell lines. Our results indicate that IAZP is a promising agent that may enhance the cytotoxic effects of doxorubicin on some cancer cells through targeting the DDR. It is a preliminary step toward the clinical application of IAZP in combination with anticancer drugs and opens the avenue for the development of compounds targeting the DDR pathway that might improve the therapeutic index of anticancer drugs and enhance their cure rate. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Studies of longitudinal profile of electron bunches and impedance measurements at Indus-2 synchrotron radiation source

    Energy Technology Data Exchange (ETDEWEB)

    Garg, Akash Deep, E-mail: akash-deep@rrcat.gov.in [Beam Diagnostics Section (BDS), Indus Operations, Beam Dynamics and Diagnostics Division (IOBDD), Raja Ramanna Centre for Advanced Technology, Indore 452 013, M.P. (India); Homi Bhabha National Institute (HBNI) at Raja Ramanna Centre for Advanced Technology, Indore (India); Yadav, S.; Kumar, Mukesh; Shrivastava, B.B.; Karnewar, A.K.; Ojha, A.; Puntambekar, T.A. [Beam Diagnostics Section (BDS), Indus Operations, Beam Dynamics and Diagnostics Division (IOBDD), Raja Ramanna Centre for Advanced Technology, Indore 452 013, M.P. (India)

    2016-04-01

    Indus-2 is a 3rd generation synchrotron radiation source at the Raja Ramanna Centre for Advanced Technology (RRCAT) in India. We study the longitudinal profile of electrons in Indus-2 by using dual sweep synchroscan streak camera at visible diagnostic beamline. In this paper, the longitudinal profiles of electron bunch are analyzed by filling beam current in a single bunch mode. These studies are carried at injection energy (550 MeV) and at ramped beam energy (2.5 GeV). The effects of the wakefield generated interactions between the circulating electrons and the surrounding vacuum chamber are analyzed in terms of measured effects on longitudinal beam distribution. The impedance of the storage ring is obtained by fitting the solutions of Haissinski equation to the measured bunch lengthening with different impedance models. The impedance of storage ring obtained by a series R+L impedance model indicates a resistance (R) of 1350±125 Ω, an inductance (L) of 180±25 nH and broadband impedance of 2.69 Ω. These results are also compared with the values obtained from measured synchronous phase advancing and scaling laws. These studies are very useful in better understanding and control of the electromagnetic interactions.

  17. Controlling nonlinear longitudinal space charge oscillations for high peak current bunch train generation

    Directory of Open Access Journals (Sweden)

    P. Musumeci

    2013-10-01

    Full Text Available The evolution of picosecond modulations of the longitudinal profile of an electron beam generated in an rf photoinjector is analyzed and optimized with the goal of obtaining high peak current electron bunch trains at very high frequencies (≥THz. Taking advantage of nonlinear longitudinal space charge forces, it is found that more than 500 A peak current 1 THz bunch trains can be generated using a standard 1.6 cell SLAC/UCLA/BNL rf gun. Postacceleration is used to freeze the longitudinal phase space dynamics after one half plasma oscillation. Applications range from tunable narrow bandwidth THz radiation generation to drivers for high frequency high gradient accelerators.

  18. Feedback for suppression of single-bunch transverse instability in electron-positron storage rings

    International Nuclear Information System (INIS)

    Smaluk, V; Sukhanov, D; Oreshonok, V; Cherepanov, V; Kiselev, V

    2012-01-01

    Transverse head-tail instability is a severe limitation of a single-bunch beam current in circular accelerators. Applicability and efficiency of feedbacks for suppression of the instability is analyzed. Both chromatic and nonlinear effects have been taken into account to understand the processes of excitation and damping of the instability. Analytical estimations are compared with the results of experiments and numerical simulations. A feedback system has been developed, installed and commissioned at the VEPP-4M electron-positron collider. An original scheme of the kicker powering has been developed to provide the necessary performance with minimal expenses. Real-time digital data processing performed by a code running in an FPGA module provides high efficiency and flexibility of the system. During the system commissioning, a more than threefold increase of intensity of the VEPP-4M single-bunch beam has been achieved.

  19. Violacein Treatment Modulates Acute and Chronic Inflammation through the Suppression of Cytokine Production and Induction of Regulatory T Cells.

    Directory of Open Access Journals (Sweden)

    Liana Verinaud

    Full Text Available Inflammation is a necessary process to control infection. However, exacerbated inflammation, acute or chronic, promotes deleterious effects in the organism. Violacein (viola, a quorum sensing metabolite from the Gram-negative bacterium Chromobacterium violaceum, has been shown to protect mice from malaria and to have beneficial effects on tumors. However, it is not known whether this drug possesses anti-inflammatory activity. In this study, we investigated whether viola administration is able to reduce acute and chronic autoimmune inflammation. For that purpose, C57BL/6 mice were intraperitoneally injected with 1 μg of LPS and were treated with viola (3.5mg/kg via i.p. at the same time-point. Three hours later, the levels of inflammatory cytokines in the sera and phenotypical characterization of leukocytes were determined. Mice treated with viola presented a significant reduction in the production of inflammatory cytokines compared with untreated mice. Interestingly, although viola is a compound derived from bacteria, it did not induce inflammation upon administration to naïve mice. To test whether viola would protect mice from an autoimmune inflammation, Experimental Autoimmune Encephalomyelitis (EAE-inflicted mice were given viola i.p. at disease onset, at the 10th day from immunization. Viola-treated mice developed mild EAE disease in contrast with placebo-treated mice. The frequencies of dendritic cells and macrophages were unaltered in EAE mice treated with viola. However, the sole administration of viola augmented the levels of splenic regulatory T cells (CD4+Foxp3+. We also found that adoptive transfer of viola-elicited regulatory T cells significantly reduced EAE. Our study shows, for the first time, that violacein is able to modulate acute and chronic inflammation. Amelioration relied in suppression of cytokine production (in acute inflammation and stimulation of regulatory T cells (in chronic inflammation. New studies must be

  20. Short bunch length detector for ion beam with high bunch density

    International Nuclear Information System (INIS)

    Tron, A.M.; Shako, V.V.

    1993-01-01

    The secondary electron rf monitors for short ion bunch phase distribution measurements are presented. Construction particularities of the monitors, influence of space charge of both the primary and the secondary electron beams on the phase resolution, thermal regime of the target during beam-target interaction are considered

  1. Phase measurement and control of bunched beams

    International Nuclear Information System (INIS)

    Lewis, R.N.

    1978-01-01

    An ion bean buncher was developed at ANL for bunching all ion species through a tandem accelerator. Transit time variations through the tandem, caused by ripple and fluctuations in the injection and lens power supplies and terminal voltage, and to varying voltage distributions in the accelerating tube, cause a beam-phase variation at the output of the tandem. A beam-phase measurement and control system was designed and installed in conjunction with the ion beam buncher to control beam phase at the tandem output. That system is described

  2. Emittance growth of bunched beams in bends

    International Nuclear Information System (INIS)

    Carlsten, B.E.; Raubenheimer, T.O.

    1995-01-01

    Talman [Phys. Rev. Lett. 56, 1429 (1986)] has proposed a novel relativistic effect that occurs when a charged particle beam is bent in the magnetic field from an external dipole. The consequence of this effect is that the space-charge forces from the particles do not exhibit the usual inverse-square energy dependence and some part of them are, in fact, independent of energy. This led to speculation that this effect could introduce significant emittance growth for a bending electron beam. Subsequently, it was shown that this effect's influence on the beam's transverse motion is canceled for a dc beam by a potential depression within the beam (to first order in the beam radius divided by the bend radius). In this paper, we extend the analysis to include short bunch lengths (as compared to the beam pipe dimensions) and find that there is no longer the cancellation for forces both transverse to and in the direction of motion. We provide an estimate for the emittance growth as a function of bend angle, beam radius, and current, and for magnetic compression of an electron bunch

  3. On some properties of longitudinal and transverse coupled-bunch instabilities

    International Nuclear Information System (INIS)

    Kamiya, Yukihide.

    1983-02-01

    Some properties of longitudinal and transverse coupled-bunch instabilities have been investigated theoretically and computationally, mainly based on a rigid-bunch model. In this report, we will study Robinson's stability, sum rules of the instabilities and the cure of instabilities by producing the oscillation frequencies different from bunch to bunch, and also give the numerical examples for KEK-PF storage ring. KEYWORD: storage ring, accelerator, bunched beam, longitudinal instability, transverse instability, coupled-bunch instability. (author)

  4. Electron bunch length measurement at the Vanderbilt FEL

    Energy Technology Data Exchange (ETDEWEB)

    Amirmadhi, F.; Brau, C.A.; Mendenhall, M. [Vanderbilt Free-Electron-Laser Center, Nashville, TN (United States)] [and others

    1995-12-31

    During the past few years, a number of experiments have been performed to demonstrate the possibility to extract the longitudinal charge distribution from spectroscopic measurements of the coherent far-infrared radiation emitted as transition radiation or synchrotron radiation. Coherent emission occurs in a spectral region where the wavelength is comparable to or longer than the bunch length, leading to an enhancement of the radiation intensity that is on the order of the number of particles per bunch, as compared to incoherent radiation. This technique is particularly useful in the region of mm and sub-mm bunch lengths, a range where streak-cameras cannot be used for beam diagnostics due to their limited time resolution. Here we report on experiments that go beyond the proof of principle of this technique by applying it to the study and optimization of FEL performance. We investigated the longitudinal bunch length of the Vanderbilt FEL by analyzing the spectrum of coherent transition radiation emitted by the electron bunches. By monitoring the bunch length while applying a bunch-compression technique, the amount of the compression could be easily observed. This enabled us to perform a systematic study of the FEL performance, especially gain and optical pulse width, as a function of the longitudinal electron distribution in the bunch. The results of this study will be presented and discussed.

  5. Electric-current-induced step bunching on Si(111)

    International Nuclear Information System (INIS)

    Homma, Yoshikazu; Aizawa, Noriyuki

    2000-01-01

    We experimentally investigated step bunching induced by direct current on vicinal Si(111)'1x1' surfaces using scanning electron microscopy and atomic force microscopy. The scaling relation between the average step spacing l b and the number of steps N in a bunch, l b ∼N -α , was determined for four step-bunching temperature regimes above the 7x7-'1x1' transition temperature. The step-bunching rate and scaling exponent differ between neighboring step-bunching regimes. The exponent α is 0.7 for the two regimes where the step-down current induces step bunching (860-960 and 1210-1300 deg. C), and 0.6 for the two regimes where the step-up current induces step bunching (1060-1190 and >1320 deg. C). The number of single steps on terraces also differs in each of the four temperature regimes. For temperatures higher than 1280 deg. C, the prefactor of the scaling relation increases, indicating an increase in step-step repulsion. The scaling exponents obtained agree reasonably well with those predicted by theoretical models. However, they give unrealistic values for the effective charges of adatoms for step-up-current-induced step bunching when the 'transparent' step model is used

  6. Instability during bunch shortening of an electron-cooled beam

    Directory of Open Access Journals (Sweden)

    M. Takanaka

    2003-10-01

    Full Text Available Bunch shortening causes an electron-cooled beam to be space charge dominated at low energies. Instability during the bunch shortening has been studied using a particle-tracking program where the 3D space-charge field due to the beam is calculated with a simplifying model.

  7. Evaluation of fruit and bunch traits in black Sigatoka resistant ...

    African Journals Online (AJOL)

    Studies involving the evaluation of fruit and bunch characteristics of twenty seven cultivars of plantain and banana were undertaken. Results showed that bunch weight of plantain hybrid, 25344-18, differed significantly (P<0.05) from all other genotypes except SH 3362, with an average of 20.8 kg plant. The number of hands ...

  8. LHC Report: spring cleaning over, bunches of luminosity

    CERN Multimedia

    CERN Bulletin

    2011-01-01

    Scrubbing was completed on Wednesday 13 April. The run had seen over 1000 bunches per beam successfully circulating at 450 GeV. Measurements showed that electron cloud activity in the cold regions had been suppressed. A decrease of vacuum activity in the warm regions demonstrated that the cleaning had also achieved the required results there. As discussed in the last Bulletin, the scrubbing was performed with high intensity bunches with 50 nanosecond spacing. Given the potential luminosity performance with this spacing (more bunches, higher bunch intensity from the injectors) and in the light of the results of the scrubbing run, the decision was taken to continue the 2011 physics run with this bunch spacing.   A few issues with 50 nanosecond spacing had to be resolved when standard operations for luminosity production resumed. Once things had been tidied up, stable beams were provided for the experiments, firstly with 228 bunches per beam and then with 336 bunches per beam. The 336 bunch fill that w...

  9. Bunched soliton states in weakly coupled sine-Gordon systems

    DEFF Research Database (Denmark)

    Grønbech-Jensen, N.; Samuelsen, Mogens Rugholm; Lomdahl, P. S.

    1990-01-01

    The interaction between solitons of two weakly coupled sine-Gordon systems is considered. In particular, the stability of bunched states is investigated, and perturbation results are compared with numerical results.......The interaction between solitons of two weakly coupled sine-Gordon systems is considered. In particular, the stability of bunched states is investigated, and perturbation results are compared with numerical results....

  10. Production of Mineral Water Using Palm Bunch Ash (PBA) From ...

    African Journals Online (AJOL)

    A public health strategy for increasing the potassium and magnesium intake of the population was explored. These electrolytes have been confirmed by epidemiological studies to have some health benefits. A process for production of mineral water using palm bunch ash was developed. The composition of the palm bunch ...

  11. Coupled-Beam and Coupled-Bunch Instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Burov, Alexey [Fermilab

    2016-06-23

    A problem of coupled-beam instability is solved for two multibunch beams with slightly different revolution frequencies, as in the Fermilab Recycler Ring (RR). Sharing of the inter-bunch growth rates between the intra-bunch modes is described. The general analysis is applied to the RR; possibilities to stabilize the beams by means of chromaticity, feedback and Landau damping are considered.

  12. Simulation of the longitudinal instabilities of the asymmetric bunches

    International Nuclear Information System (INIS)

    Dai Jianping; Zhao Zhentang

    2002-01-01

    The computational model of the code used to simulate the longitudinal instabilities of the asymmetric bunches was introduced. The growth rates of the longitudinal instabilities of the symmetric bunches got by this code were compared with those got by the code ZAP, and they were almost the same. As an example, the simulation results of the BEPC-II were presented

  13. Longitudinal Bunch Position Control for the Super-B Accelerator

    International Nuclear Information System (INIS)

    Bertsche, Kirk; Rivetta, Claudio; Sullivam, Michael K.; SLAC; Drago, Alessandro; Frascati

    2009-01-01

    The use of normal conducting cavities and an ion-clearing gap will cause a significant RF accelerating voltage gap transient and longitudinal phase shift of the individual bunches along the bunch train in both rings of the SuperB accelerator. Small relative centroid position shifts between bunches of the colliding beams will have a large adverse impact on the luminosity due to the small β* y at the interaction point (IP). We investigate the possibility of minimizing the relative longitudinal position shift between bunches by reducing the gap transient in each ring and matching the longitudinal bunch positions of the two rings at the IP using feedback/feedforward techniques in the LLRF. The analysis is conducted assuming maximum use of the klystron power installed in the system

  14. Study of nonlinear interaction between bunched beam and intermediate cavities in a relativistic klystron amplifier

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Y. [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900 (China); Science and Technology on High Power Microwave Laboratory, Mianyang 621900 (China); Xu, Z.; Li, Z. H. [Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900 (China); Tang, C. X. [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China)

    2012-07-15

    In intermediate cavities of a relativistic klystron amplifier (RKA) driven by intense relativistic electron beam, the equivalent circuit model, which is widely adopted to investigate the interaction between bunched beam and the intermediate cavity in a conventional klystron design, is invalid due to the high gap voltage and the nonlinear beam loading in a RKA. According to Maxwell equations and Lorentz equation, the self-consistent equations for beam-wave interaction in the intermediate cavity are introduced to study the nonlinear interaction between bunched beam and the intermediate cavity in a RKA. Based on the equations, the effects of modulation depth and modulation frequency of the beam on the gap voltage amplitude and its phase are obtained. It is shown that the gap voltage is significantly lower than that estimated by the equivalent circuit model when the beam modulation is high. And the bandwidth becomes wider as the beam modulation depth increases. An S-band high gain relativistic klystron amplifier is designed based on the result. And the corresponding experiment is carried out on the linear transformer driver accelerator. The peak output power has achieved 1.2 GW with an efficiency of 28.6% and a gain of 46 dB in the corresponding experiment.

  15. Study of nonlinear interaction between bunched beam and intermediate cavities in a relativistic klystron amplifier

    Science.gov (United States)

    Wu, Y.; Xu, Z.; Li, Z. H.; Tang, C. X.

    2012-07-01

    In intermediate cavities of a relativistic klystron amplifier (RKA) driven by intense relativistic electron beam, the equivalent circuit model, which is widely adopted to investigate the interaction between bunched beam and the intermediate cavity in a conventional klystron design, is invalid due to the high gap voltage and the nonlinear beam loading in a RKA. According to Maxwell equations and Lorentz equation, the self-consistent equations for beam-wave interaction in the intermediate cavity are introduced to study the nonlinear interaction between bunched beam and the intermediate cavity in a RKA. Based on the equations, the effects of modulation depth and modulation frequency of the beam on the gap voltage amplitude and its phase are obtained. It is shown that the gap voltage is significantly lower than that estimated by the equivalent circuit model when the beam modulation is high. And the bandwidth becomes wider as the beam modulation depth increases. An S-band high gain relativistic klystron amplifier is designed based on the result. And the corresponding experiment is carried out on the linear transformer driver accelerator. The peak output power has achieved 1.2 GW with an efficiency of 28.6% and a gain of 46 dB in the corresponding experiment.

  16. Simulations of the ILC Electron Gun and Electron Bunching System

    International Nuclear Information System (INIS)

    Haakonsen, C.B.; McGill U.

    2006-01-01

    The International Linear Collider (ILC) is a proposed electron-positron collider, expected to provide insight into important questions in particle physics. A part of the global R and D effort for the ILC is the design of its electron gun and electron bunching system. The present design of the bunching system has two sub-harmonic bunchers, one operating at 108 MHz and one at 433MHz, and two 5-cell 1.3 GHz (L-band) bunchers. This bunching system has previously been simulated using the Phase and Radial Motion in Electron Linear Accelerators (PARMELA) software, and those simulations indicated that the design provides sufficient bunching and acceleration. Due to the complicated dynamics governing the electrons in the bunching system we decided to verify and expand the PARMELA results using the more recent and independent simulation software General Particle Tracer (GPT). GPT tracks the motion and interactions of a set of macro particles, each of which represent a number of electrons, and provides a variety of analysis capabilities. To provide initial conditions for the macro particles, a method was developed for deriving the initial conditions from detailed simulations of particle trajectories in the electron gun. These simulations were performed using the Egun software. For realistic simulation of the L-band bunching cavities, their electric and magnetic fields were calculated using the Superfish software and imported into GPT. The GPT simulations arrived at similar results to the PARMELA simulations for sub-harmonic bunching. However, using GPT it was impossible to achieve an efficient bunching performance of the first L-band bunching cavity. To correct this, the first L-band buncher cell was decoupled from the remaining 4 cells and driven as an independent cavity. Using this modification we attained results similar to the PARMELA simulations. Although the modified bunching system design performed as required, the modifications are technically challenging to implement

  17. Bunch mode specific rate corrections for PILATUS3 detectors

    Energy Technology Data Exchange (ETDEWEB)

    Trueb, P., E-mail: peter.trueb@dectris.com [DECTRIS Ltd, 5400 Baden (Switzerland); Dejoie, C. [ETH Zurich, 8093 Zurich (Switzerland); Kobas, M. [DECTRIS Ltd, 5400 Baden (Switzerland); Pattison, P. [EPF Lausanne, 1015 Lausanne (Switzerland); Peake, D. J. [School of Physics, The University of Melbourne, Victoria 3010 (Australia); Radicci, V. [DECTRIS Ltd, 5400 Baden (Switzerland); Sobott, B. A. [School of Physics, The University of Melbourne, Victoria 3010 (Australia); Walko, D. A. [Argonne National Laboratory, Argonne, IL 60439 (United States); Broennimann, C. [DECTRIS Ltd, 5400 Baden (Switzerland)

    2015-04-09

    The count rate behaviour of PILATUS3 detectors has been characterized for seven bunch modes at four different synchrotrons. The instant retrigger technology of the PILATUS3 application-specific integrated circuit is found to reduce the dependency of the required rate correction on the synchrotron bunch mode. The improvement of using bunch mode specific rate corrections based on a Monte Carlo simulation is quantified. PILATUS X-ray detectors are in operation at many synchrotron beamlines around the world. This article reports on the characterization of the new PILATUS3 detector generation at high count rates. As for all counting detectors, the measured intensities have to be corrected for the dead-time of the counting mechanism at high photon fluxes. The large number of different bunch modes at these synchrotrons as well as the wide range of detector settings presents a challenge for providing accurate corrections. To avoid the intricate measurement of the count rate behaviour for every bunch mode, a Monte Carlo simulation of the counting mechanism has been implemented, which is able to predict the corrections for arbitrary bunch modes and a wide range of detector settings. This article compares the simulated results with experimental data acquired at different synchrotrons. It is found that the usage of bunch mode specific corrections based on this simulation improves the accuracy of the measured intensities by up to 40% for high photon rates and highly structured bunch modes. For less structured bunch modes, the instant retrigger technology of PILATUS3 detectors substantially reduces the dependency of the rate correction on the bunch mode. The acquired data also demonstrate that the instant retrigger technology allows for data acquisition up to 15 million photons per second per pixel.

  18. Implementation of the Electronics Chain for the Bunch by Bunch Intensity Measurement Devices for the LHC

    CERN Document Server

    Belohrad, D; Ludwig, M; Savioz, J J; Thoulet, S

    2009-01-01

    The fast beam intensity measurements for the LHC are provided by eight Fast Beam Current Transformers (FBCT). Four FBCTs installed in the LHC rings are capable of providing both bunch-by-bunch and total turn-by-turn beam intensity information. A further four FBCTs, two in each of the LHC dump lines, are used to measure the total extracted beam intensity. In addition to providing intensity information the ring FBCTs also send signals to the machine protection system. This increases the complexity of both the RF front-end and the digital acquisition parts of the signal processing chain. The aim of this paper is to discuss the implemented hardware solution for the FBCT system, in particular with respect to the signal distribution, FPGA signal processing, calibration, and interaction of the FBCTs with the machine protection chain.

  19. Integration of energy-efficient empty fruit bunch drying with gasification/combined cycle systems

    International Nuclear Information System (INIS)

    Aziz, Muhammad; Prawisudha, Pandji; Prabowo, Bayu; Budiman, Bentang Arief

    2015-01-01

    Highlights: • Novel integrated drying, gasification and combined cycle for empty fruit bunch. • Application of enhanced process integration to achieve high total energy efficiency. • The technology covers exergy recovery and process integration. • High overall energy efficiency can be achieved (about 44% including drying). - Abstract: A high-energy-efficient process for empty fruit bunch drying with integration to gasification and combined cycle processes is proposed. The enhancement is due to greater exergy recovery and more efficient process integration. Basically, the energy/heat involved in a single process is recovered as much as possible, leading to minimization of exergy destruction. In addition, the unrecoverable energy/heat is utilized for other processes through process integration. During drying, a fluidized bed dryer with superheated steam is used as the main evaporator. Exergy recovery is performed through exergy elevation via compression and effective heat coupling in a dryer and heat exchangers. The dried empty fruit bunches are gasified in a fluidized bed gasifier using air as the fluidizing gas. Furthermore, the produced syngas is utilized as fuel in the combined cycle module. From process analysis, the proposed integrated processes can achieve a relatively high energy efficiency. Compared to a standalone drying process employing exergy recovery, the proposed integrated drying can reduce consumed energy by about 1/3. In addition, the overall integrated processes can reach a total power generation efficiency of about 44%

  20. Analytical model and error analysis of arbitrary phasing technique for bunch length measurement

    Science.gov (United States)

    Chen, Qushan; Qin, Bin; Chen, Wei; Fan, Kuanjun; Pei, Yuanji

    2018-05-01

    An analytical model of an RF phasing method using arbitrary phase scanning for bunch length measurement is reported. We set up a statistical model instead of a linear chirp approximation to analyze the energy modulation process. It is found that, assuming a short bunch (σφ / 2 π → 0) and small relative energy spread (σγ /γr → 0), the energy spread (Y =σγ 2) at the exit of the traveling wave linac has a parabolic relationship with the cosine value of the injection phase (X = cosφr|z=0), i.e., Y = AX2 + BX + C. Analogous to quadrupole strength scanning for emittance measurement, this phase scanning method can be used to obtain the bunch length by measuring the energy spread at different injection phases. The injection phases can be randomly chosen, which is significantly different from the commonly used zero-phasing method. Further, the systematic error of the reported method, such as the influence of the space charge effect, is analyzed. This technique will be especially useful at low energies when the beam quality is dramatically degraded and is hard to measure using the zero-phasing method.

  1. Study on the Effect of Calcium and Potassium Spray on Date Bunch Fading Disorder

    Directory of Open Access Journals (Sweden)

    Hosein Shekofteh

    2017-09-01

    weight, fruit length, fruit diameter, stone weight, stone diameter, and bunch fading percentage at 1℅ level. The highest wet fruit weight, fruit length, fruit diameter, stone weight, and stone diameter were attained in the treatment containing combined application of calcium nitrate and potassium sulfate. Furthermore, the lowest amounts of these traits were obtained in control. The lowest and highest percentage of date bunch fading belonged to the combined treatment of calcium nitrate and potassium sulfate, and control, respectively. In general, application of calcium nitrate and potassium sulfate with each other improved fruit traits and reduced bunch fading percentage. Calcium mobility in the plant takes place mainly in the xylem, together with water. Therefore, calcium uptake is directly related to plant transpiration rate. Conditions of high humidity, cold and low transpiration rates may result in calcium deficiency. Salinity might also cause calcium deficiency because it decreases water uptake by the plant. Since calcium mobility in plants is limited, calcium deficiency appears in younger leaves and in fruits, because they have a very low transpiration rate. Therefore, it is necessary to have a constant supply of calcium for continued growth. Calcium deficiency is usually caused by low calcium availability or water stress which results in low transpiration rates. Calcium is an essential plant nutrient with many roles including participation in metabolic processes of other nutrients uptake, promotion of proper plant cell elongation, and improvement of cell wall structure – calcium is an essential part of plant cell wall. It forms calcium pectate compounds which give stability to cell walls and bind cells together. It also helps protecting the plant against heat stress - calcium improves stomata function and participates in induction of heat shock proteins. In addition, it helps protecting the plant against diseases - numerous fungi and bacteria secret enzymes

  2. Mode-coupling theory and bunch lengthening in SPEAR II

    International Nuclear Information System (INIS)

    Suzuki, T.; Chin, Y.; Satoh, K.

    1983-01-01

    A mode-coupling theory of bunched-beam instabilities is developed for a Gaussian bunch. The theory converts Sacherer's integral equation with mode coupling into a matrix eigenvalue problem. The present theory assumes well-defined azimuthal modes and takes into account radial modes which are expressed as superpositions of orthogonal functions. The theory is applied to bunch lengthening observed at SPEAR II. The theory explains qualitative features of the experimental results fairly well, but quantitative agreement is not too good. This is ascribed to insufficient knowledge of the coupling impedance of SPEAR II or to the possibility that such effects as radiation damping and quantum excitation should be included. (author)

  3. Multiple bunch-splitting in the PS results and plans

    CERN Document Server

    Garoby, R

    2001-01-01

    The nominal longitudinal characteristics of the PS proton beam for the LHC were attained during the year 2000, using a sequence of triple- and double-splittings to divide each PS Booster (PSB) bunch into 12. This method minimizes longitudinal emittance blow-up and preserves a gap, free of particles, in the bunch train. Some of the ideas for alternative bunch trains have also been tested. The performance achieved is described and the sources of limitations are discussed together with the foreseen improvements.

  4. Resistive wall wakefields of short bunches at cryogenic temperatures

    Directory of Open Access Journals (Sweden)

    G. Stupakov

    2015-03-01

    Full Text Available We present calculations of the longitudinal wakefields at cryogenic temperatures for extremely short bunches, characteristic for modern x-ray free electron lasers. The calculations are based on the equations for the surface impedance in the regime of the anomalous skin effect in metals. This paper extends and complements an earlier analysis of B. Podobedov, Phys. Rev. ST Accel. Beams 12, 044401 (2009. into the region of very high frequencies associated with bunch lengths in the micron range. We study in detail the case of a rectangular bunch distribution for parameters of interest of LCLS-II with a superconducting undulator.

  5. Interaction of an ion bunch with a plasma slab

    Energy Technology Data Exchange (ETDEWEB)

    Krasovitskiy, V. B., E-mail: krasovit@mail.ru [Russian Academy of Sciences, Keldysh Institute of Applied Mathematics (Russian Federation); Turikov, V. A. [Peoples’ Friendship University of Russia (Russian Federation)

    2016-11-15

    Charge neutralization of a short ion bunch passing through a plasma slab is studied by means of numerical simulation. It is shown that a fraction of plasma electrons are trapped by the bunch under the action of the collective charge separation field. The accelerated electrons generated in this process excite beam−plasma instability, thereby violating the trapping conditions. The process of electron trapping is also strongly affected by the high-frequency electric field caused by plasma oscillations at the slab boundaries. It is examined how the degree of charge neutralization depends on the parameters of the bunch and plasma slab.

  6. Developing electron beam bunching technology for improving light sources

    International Nuclear Information System (INIS)

    Carlsten, B.E.; Chan, K.C.D.; Feldman, D.W.

    1997-01-01

    This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). The goal of this project was to develop a new electron bunch compression technology, experimentally demonstrate subpicosecond compression of bunches with charges on the order of 1 nC, and to theoretically investigate fundamental limitations to electron bunch compression. All of these goals were achieved, and in addition, the compression system built for this project was used to generate 22 nm light in a plasma-radiator light source

  7. Electron Bunch Length Diagnostic With Coherent Smith-Purcell Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, D.C.

    1997-05-12

    The authors have designed a new technique for measuring subpicosecond electron bunch lengths using coherent Smith-Purcell radiation. This new diagnostic technique involves passing the electron beam in close proximity of a grating with a period comparable to the electron bunch length. The emitted Smith-Purcell radiation will have a coherent component whose angular position and distribution are directly related to the electron bunch length and longitudinal profile, respectively. This new diagnostic technique is inherently simple, inexpensive and non-intercepting. The authors show that the new technique is also scaleable to femtosecond regime.

  8. Function of bunching segment in multi-cell RF gun

    International Nuclear Information System (INIS)

    Yang Xingfan; Xu Zhou Liu Xisan

    2001-01-01

    With a bunching segment and a shortened first cell, the 4 + 1/2 cell RF gun produced in CAEP has been proved experimentally to be effective in reducing electron back bombardment. The analysis of the electric field distribution and electron motion in bunching segment of multi-cell RF gun is presented. The electron capture efficiency and electron trajectory with different initial phase are calculated using Runge-Kutta method. The function of the bunching segment is discussed. The calculated parameters of the 4 + 1/2 cell RF gun agree well with the experimental results

  9. Transverse-Longitudinal Coupling Effect in Laser Bunch Slicing

    International Nuclear Information System (INIS)

    Shimada, M.; Katoh, M.; Adachi, M.; Kimura, S.; Tanikawa, T.; Hosaka, M.; Yamamoto, N.; Takashima, Y.; Takahashi, T.

    2009-01-01

    We report turn-by-turn observation of coherent synchrotron radiation (CSR) produced by the laser bunch slicing technique at an electron storage ring operated with a small momentum compaction factor. CSR emission was intermittent, and its interval depended strongly on the betatron tune. This peculiar behavior of the CSR could be interpreted as a result of coupling between the transverse and longitudinal motion of the electrons. This is the first observation of such an effect, which would be important not only for controlling the CSR emission but also for generating and transporting ultrashort electron bunches or electron bunches with microdensity structures in advanced accelerators.

  10. Electron Bunch Length Diagnostic With Coherent Smith-Purcell Radiation

    International Nuclear Information System (INIS)

    Nguyen, D.C.

    1997-01-01

    The authors have designed a new technique for measuring subpicosecond electron bunch lengths using coherent Smith-Purcell radiation. This new diagnostic technique involves passing the electron beam in close proximity of a grating with a period comparable to the electron bunch length. The emitted Smith-Purcell radiation will have a coherent component whose angular position and distribution are directly related to the electron bunch length and longitudinal profile, respectively. This new diagnostic technique is inherently simple, inexpensive and non-intercepting. The authors show that the new technique is also scaleable to femtosecond regime

  11. Longitudinal Electron Bunch Diagnostics Using Coherent Transition Radiation

    CERN Document Server

    Mihalcea, Daniel; Happek, Uwe; Regis-Guy Piot, Philippe

    2005-01-01

    The longitudinal charge distribution of electron bunches in the Fermilab A0 photo-injector was determined by using the coherent transition radiation produced by electrons passing through a thin metallic foil. The auto-correlation of the transition radiation signal was measured with a Michelson type interferometer. The response function of the interferometer was determined from measured and simulated power spectra for low electron bunch charge and maximum longitudinal compression. Kramers-Kroning technique was used to determine longitudinal charge distribution. Measurements were performed for electron bunch lengths in the range from 0.3 to 2 ps (rms).

  12. Chicane and wiggler based bunch compressors for future linear colliders

    International Nuclear Information System (INIS)

    Raubenheimer, T.O.; Emma, P.; Kheifets, S.

    1993-05-01

    In this paper, we discuss bunch compressors for future linear colliders. In the past, the bunch compression optics has been based upon achromatic cells using strong sextupoles to correct the dispersive and betatron chromaticity. To preserve the very small emittances required in most future collider designs, these schemes tend to have very tight alignment tolerances. Here, we describe bunch compressors based upon magnetic chicanes or wigglers which do need sextupoles to correct the chromatic emittance dilution. The dispersive chromaticity cancels naturally and the betatron chromaticity is not a significant source of emittance dilution. Thus, these schemes allow for substantially reduced alignment tolerances. Finally, we present a detailed design for the NLC linear collider

  13. New diagnostics and cures for coupled-bunch instabilities

    International Nuclear Information System (INIS)

    Prabhakar, S.

    2000-01-01

    Electromagnetic interaction between a charged particle beam and its surroundings causes collective instabilities, which must be controlled if the new light sources and colliders are to meet their design goals. Control requires a combination of passive damping and fast active feedback on an unprecedented technological scale. Efficient instability diagnosis techniques are also needed for machines with large numbers of bunches. This thesis describes new methods of measuring and analyzing coupled-bunch instabilities in circular accelerators, and demonstrates the existence of a new cure. A new technique is demonstrated for simultaneous measurement of growth rates, damping rates and coherent tune shifts of all unstable coupled-bunch eigenmodes from a single 10-25-ms transient snapshot of beam motion. The technique has been used to locate and quantify beam impedance resonances at PEP-II, ALS and SPEAR. This method is faster than existing spectral scan methods by at least an order of magnitude, and has the added advantage of revealing coupled-bunch dynamics in the linear small-signal regime. A method is also presented for estimating beam impedance from multi-bunch fill shape and synchronous phase measurements. Phase space tracking of multi-bunch instabilities is introduced as a ''complete instability diagnostic.'' Digitized multi-bunch data is analyzed offline, to estimate the phase space trajectories of bunches and modes. Availability of phase space trajectories is shown to open up a variety of possibilities, including measurement of reactive impedance, and diagnosis of the fast beam-ion instability. Knowledge gained from longitudinal measurements (all made using a digital longitudinal feedback system) has been used to optimize cavity temperatures, tuner positions and feedback parameters, and also to identify sources of beam noise at the three machines. A matrix-based method is presented for analyzing the beneficial effect of bunch-to-bunch tune variation on instability

  14. Simultaneous detection of longitudinal and transverse bunch signals at ANKA

    Energy Technology Data Exchange (ETDEWEB)

    Kehrer, Benjamin; Blomley, Edmund; Brosi, Miriam; Bruendermann, Erik; Hiller, Nicole; Mueller, Anke-Susanne; Steinmann, Johannes; Schedler, Manuel; Schuh, Marcel; Schoenfeldt, Patrik; Smale, Nigel [Karlsruhe Institute of Technology, Karlsruhe (Germany); Schuetze, Paul [Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)

    2016-07-01

    The ANKA storage ring offers different operation modes including the short-bunch mode with bunch lengths tuned down to a few picoseconds. This can lead to the occurrence of microwave instabilities coupled to the emission of coherent synchrotron radiation (CSR) in the so-called 'bursts'. To study this CSR instability we use several turn-by-turn enabled detector systems to synchronously measure both the THz signal as well as bunch profiles. The different detectors are placed at different locations around the storage ring. Here we discuss the experimental setup and calibration of the various systems' synchronisation.

  15. Bunch monitor for an S-band electron linear accelerator

    International Nuclear Information System (INIS)

    Otake, Yuji; Nakahara, Kazuo

    1991-01-01

    The measurement of bunch characteristics in an S-band electron linear accelerator is required in order to evaluate the quality of accelerated electron beams. A new-type bunch monitor has been developed which combines micro-stripline technology with an air insulator and wall-current monitoring technology. The obtained time resolution of the monitor was more than 150 ps. This result shows that the monitor can handle the bunch number of an S-band linac. The structure of the monitor is suitable for being installed in the vacuum area, since it is constructed of only metal and ceramic parts. It can therefore easily be employed in an actual machine

  16. Method of controlling coherent synchroton radiation-driven degradation of beam quality during bunch length compression

    Science.gov (United States)

    Douglas, David R [Newport News, VA; Tennant, Christopher D [Williamsburg, VA

    2012-07-10

    A method of avoiding CSR induced beam quality defects in free electron laser operation by a) controlling the rate of compression and b) using a novel means of integrating the compression with the remainder of the transport system: both are accomplished by means of dispersion modulation. A large dispersion is created in the penultimate dipole magnet of the compression region leading to rapid compression; this large dispersion is demagnified and dispersion suppression performed in a final small dipole. As a result, the bunch is short for only a small angular extent of the transport, and the resulting CSR excitation is small.

  17. Electric field detection of coherent synchrotron radiation in a storage ring generated using laser bunch slicing

    International Nuclear Information System (INIS)

    Katayama, I.; Shimosato, H.; Bito, M.; Furusawa, K.; Adachi, M.; Zen, H.; Kimura, S.; Katoh, M.; Shimada, M.; Yamamoto, N.; Hosaka, M.; Ashida, M.

    2012-01-01

    The electric field of coherent synchrotron radiation (CSR) generated by laser bunch slicing in a storage ring has been detected by an electro-optic sampling method. The gate pulses for sampling are sent through a large-mode-area photonic-crystal fiber. The observed electric field profile of the CSR is in good agreement with the spectrum of the CSR observed using Fourier transform far-infrared spectrometry, indicating good phase stability in the CSR. The longitudinal density profiles of electrons modulated by laser pulses were evaluated from the electric field profile.

  18. Labor Induction

    Science.gov (United States)

    f AQ FREQUENTLY ASKED QUESTIONS FAQ154 LABOR, DELIVERY, AND POSTPARTUM CARE Labor Induction • What is labor induction? • Why is labor induced? • What is the Bishop score? • What is “ripening ...

  19. Investigation of transient processes at the DELTA electron storage ring using a digital bunch-by-bunch feedback system

    Energy Technology Data Exchange (ETDEWEB)

    Hoener, Markus

    2015-07-01

    At the 1.5-GeV synchrotron radiation source DELTA, operated by the TU Dortmund University, intensive synchrotron radiation in the spectral range from hard X-rays to THz radiation is generated by the circular deflection of highly relativistic electron bunches. Interacting with the vacuum chamber wall, the electron bunches create electric fields, which can act back on subsequent bunches. With increasing beam current, the excitation is enhanced so that the electron beam is unstable, which means that the electron bunches oscillate longitudinally or transversely relative to their reference position. The oscillations reduce the quality of the synchrotron radiation and limit the maximum storable beam current. Within the scope of this thesis, the beam instabilities at the storage ring were systematically investigated. A digital bunch-by-bunch feedback system was installed and commissioned, which allows to detect and digitize the position of each electron bunch at each turn. Based on the input signal, a correction signal is calculated in order to suppress transverse and longitudinal oscillation of the bunches. In addition, it is possible to excite dedicated bunches. The systematic excitation of all coupled-bunch modes allowed for the first time to determine the damping rates of all 192 eigenmodes of the electron beam. The current dependence of the damping rates was investigated and an instability threshold was found. Besides the investigation of multibunch instabilities, single-bunch instabilities are discussed. In addition, the acquisition unit of the digital feedback system can be triggered on external events. This was used to investigate the injection process and beam losses. It was shown that the transverse feedback system increases the injection efficiency. Another aspect of this thesis is the improvement of the signal quality of ultrashort coherent synchrotron radiation pulses, which are generated by the short-pulse facility at DELTA. The short-pulse facility is based

  20. Bunch arrival time monitors; Concepts towards improving the sensitivity for low charge operation for FLASH II and XFEL

    Energy Technology Data Exchange (ETDEWEB)

    Penirschke, Andreas; Angelovski, Aleksandar; Jakoby, Rolf [TU Darmstadt, Institut fuer Mikrowellentechnik und Photonik, Merckstr. 25, 64283 Darmstadt (Germany); Sydlo, Cezary; Bousonville, Michael; Czwalinna, Marie Kristin; Schlarb, Holger [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Kuhl, Alexander [University of Hamburg, Physics Department, Accelerator Physics Group (Germany); Weiland, Thomas [Technische Univ. Darmstadt (Germany). Inst. fuer Theorie Elektromagnetischer Felder

    2013-07-01

    High gain Free-Electron Lasers can generate ultra short X-ray pulses in the femtosecond range. For a stable operation of the FEL, the precise knowledge of the bunch arrival time is crucial. A novel high bandwidth Bunch Arrival time Monitor was recently installed at FLASH to allow a low charge operation mode with a sub-10 fs resolution for bunch charges of 20 pC or more. The BAM is equipped with cone shaped pickups for the precise measurement of both, the high and low bunch charge operation mode. For the extension of FLASH facility to FLASH II new pickups for the high bandwidth BAMs need to be developed. The new BAM needs to maximize the voltage level of the beam induced signal for low charge operation mode in order to provide sufficient signal strength for the subsequent electronics. In this talk, we present concepts to improve the signal strength at the electro-optic modulators for low charge operation at FLASH II and XFEL.

  1. Measurements on Prototype Inductive Adders with Ultra-Flat-Top Output Pulses for CLIC DR Kickers

    CERN Document Server

    Holma, J; Belver-Aguilar, C

    2014-01-01

    The CLIC study is investigating the technical feasibility of an electron-positron collider with high luminosity and a nominal centre-of-mass energy of 3 TeV. The CLIC pre-damping rings and damping rings (DRs) will produce ultra-low emittance beam with high bunch charge. To avoid beam emittance increase, the DR kicker systems must provide extremely flat, high-voltage, pulses. The specifications for the DR extraction kickers call for a 160 ns duration flat-top pulses of ±12.5 kV, 250 A, with a combined ripple and droop of not more than ±0.02 % (±2.5 V). An inductive adder is a very promising approach to meeting the specifications because this topology allows the use of both passive and analogue modulation methods to adjust the output waveform. Recently, two five-layer, 3.5 kV, prototype inductive adders have been built at CERN. The first of these has been used to test the passive and active analogue modulation methods to compensate voltage droop and ripple of the output pulses. Pulse waveforms have been reco...

  2. Effects of emittance and space-charge in femtosecond bunch compression

    International Nuclear Information System (INIS)

    Kan, K.; Yang, J.; Kondoh, T.; Norizawa, K.; Yoshida, Y.

    2008-01-01

    Ultrashort electron bunches of the order of <100fs are essential for the study of ultrafast reactions and phenomena by means of time-resolved pump-probe experiments. In order to generate such an electron bunch, the effects of emittance, space-charge (SC) and coherent synchrotron radiation (CSR) on the bunch length in a femtosecond magnetic bunch compressor were studied theoretically. It was observed that the bunch length is dominated by the emittance, SC and CSR effects when the electron bunch is compressed into a femtosecond electron bunch. The increases in bunch length due to the transverse emittance, SC and CSR effects in the bunch compressor were 1.7 fs/mm mrad, 107 fs/nC and 72 fs/nC, respectively. Finally, the simulated bunch length was compared with the experimental results.

  3. Bunched soliton states in weakly coupled sine-Gordon systems

    International Nuclear Information System (INIS)

    Gronbech-Jensen, N.; Samuelsen, M.R.; Lomdahl, P.S.; Blackburn, J.A.

    1990-01-01

    The interaction between solitons of two weakly coupled sine-Gordon systems is considered. In particular, the stability of bunched states is investigated, and perturbation results are compared with numerical results

  4. Three bunch energy stabilization for the SLC injector

    International Nuclear Information System (INIS)

    Sheppard, J.C.; Almog, I.; Bambade, P.S.; Clendenin, J.E.; Jobe, R.K.; Phinney, N.; Shoaee, H.; Stiening, R.F.; Thompson, K.A.

    1986-09-01

    Slow feedback has been developed to control the energy and energy spread of the beams which are injected into the SLC damping rings. Within a single RF pulse, two bunches of electrons and one bunch of positrons are accelerated to an energy of 1.21 GeV in the injector of the SLC. The two electron bunches are deflected into the north damping ring while the positrons are targeted into the south ring. In order to fit into the acceptance of the rings, the composite energy deviation and energy spread of the beams must be less than 2% full width. Control of the beam energy characteristics is accomplished with a set of computer controlled feedback loops which monitor the parameters of the three bunches and make adjustments to the available RF energy, RF phasing, and RF timing. This paper presents an overview of the feedback algorithms and of the special hardware developments, and reports on the operational status of the processes

  5. Review of Coupled Bunch Instabilities in the LHC

    CERN Document Server

    Angal-Kalinin, Deepa

    2002-01-01

    In order to reach the required luminosity, the LHC will have a large number of high intensity bunches. Coupled bunch instabilities can therefore be excited by the higher order modes (HOMs)of the RF cavities, by parasitic cavities and by the transverse resistive wall effect. This report summarises the growth times of the coupled bunch instabilities taking into account the HOMs (damped or undamped)relevant for the 200 MHz normal conducting cavities, the 400 MHz superconducting cavities, as well as other parasitic cavities. It is shown that, with the damped HOMs of the RF cavities, the coupled bunch instabilities remain within control for the LHC operation.As far as the transverse resistive wall effect at injection disconcerned,it is demonstrated that the corresponding growth times can be safely compensated by the proposed transverse feedback system [1].

  6. Induction linacs

    International Nuclear Information System (INIS)

    Keefe, D.

    1986-07-01

    The principle of linear induction acceleration is described, and examples are given of practical configurations for induction linacs. These examples include the Advanced Technology Accelerator, Long Pulse Induction Linac, Radial Line Accelerator (RADLAC), and Magnetically-Insulated Electron-Focussed Ion Linac. A related concept, the auto accelerator, is described in which the high-current electron-beam technology in the sub-10 MeV region is exploited to produce electron beams at energies perhaps as high as the 100 to 1000 MeV range. Induction linacs for ions are also discussed. The efficiency of induction linear acceleration is analyzed

  7. Electron density modulation in a pulsed dual-frequency (2/13.56 MHz) dual-antenna inductively coupled plasma discharge

    Energy Technology Data Exchange (ETDEWEB)

    Sirse, Nishant, E-mail: nishant.sirse@dcu.ie [Plasma Research Laboratory, School of Physical Sciences, Dublin City University, Dublin 9 (Ireland); Mishra, Anurag [Department of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do 440-746 (Korea, Republic of); Yeom, Geun Y. [Department of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do 440-746, South Korea and SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon, Gyeunggi-do 440-746 (Korea, Republic of); Ellingboe, Albert R. [Plasma Research Laboratory, School of Physical Sciences, Dublin City University, Dublin 9, Ireland and Department of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Gyeonggi-do 440-746 (Korea, Republic of)

    2016-09-15

    The electron density, n{sub e}, modulation is measured experimentally using a resonance hairpin probe in a pulsed, dual-frequency (2/13.56 MHz), dual-antenna, inductively coupled plasma discharge produced in argon-C{sub 4}F{sub 8} (90–10) gas mixtures. The 2 MHz power is pulsed at a frequency of 1 kHz, whereas 13.56 MHz power is applied in continuous wave mode. The discharge is operated at a range of conditions covering 3–50 mTorr, 100–600 W 13.56 MHz power level, 300–600 W 2 MHz peak power level, and duty ratio of 10%–90%. The experimental results reveal that the quasisteady state n{sub e} is greatly affected by the 2 MHz power levels and slightly affected by 13.56 MHz power levels. It is observed that the electron density increases by a factor of 2–2.5 on increasing 2 MHz power level from 300 to 600 W, whereas n{sub e} increases by only ∼20% for 13.56 MHz power levels of 100–600 W. The rise time and decay time constant of n{sub e} monotonically decrease with an increase in either 2 or 13.56 MHz power level. This effect is stronger at low values of 2 MHz power level. For all the operating conditions, it is observed that the n{sub e} overshoots at the beginning of the on-phase before relaxing to a quasisteady state value. The relative overshoot density (in percent) depends on 2 and 13.56 MHz power levels. On increasing gas pressure, the n{sub e} at first increases, reaching to a maximum value, and then decreases with a further increase in gas pressure. The decay time constant of n{sub e} increases monotonically with pressure, increasing rapidly up to 10 mTorr gas pressure and at a slower rate of rise to 50 mTorr. At a fixed 2/13.56 MHz power level and 10 mTorr gas pressure, the quasisteady state n{sub e} shows maximum for 30%–40% duty ratio and decreases with a further increase in duty ratio.

  8. Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6

    International Nuclear Information System (INIS)

    Chen, Y.-C.; Chow, J.-M.; Lin, C.-W.; Wu, C.-Y.; Shen, S.-C.

    2006-01-01

    -induced cell death. These data indicate that BE possesses abilities to inhibit ROS-mediated cytotoxic effects through modulation of ERKs activation and induction of HO-1 protein expression. The role of HO-1 in ROS-scavenging activity of BE is proposed

  9. Coupled-bunch instabilities in the APS ring

    International Nuclear Information System (INIS)

    Emery, L.

    1991-01-01

    A study of coupled bunch instabilities for the APS storage ring is presented. The instabilities are driven by the higher-order modes of the fifteen 352-MHz single-cell RF cavities. These modes are modeled using the 2-D cavity program URMEL. The program ZAP is then used to estimate the growth time of the instabilities for an equally-spaced bunch pattern. The cavity modes most responsible for the instabilities will be singles out for damping. 7 refs., 5 tabs

  10. Nonlinear space charge effect of bunched beam in linac

    International Nuclear Information System (INIS)

    Chen Yinbao

    1992-02-01

    The nonlinear space charge effect due to the nonuniform particle density distribution in bunched beam of a linac is discussed. The formulae of nonlinear space charge effect and nonlinear focusing forces were derived for the bunched beam with Kapchinskij-Vladimirskij (K-V) distribution, waterbag (WB) distribution, parabolic (PA) distribution, and Gauss (GA) distribution in both of the space charge disk model and space charge cylinder model in the waveguide of a linac

  11. Velocity bunching of high-brightness electron beams

    Directory of Open Access Journals (Sweden)

    S. G. Anderson

    2005-01-01

    Full Text Available Velocity bunching has been recently proposed as a tool for compressing electron beam pulses in modern high brightness photoinjector sources. This tool is familiar from earlier schemes implemented for bunching dc electron sources, but presents peculiar challenges when applied to high current, low emittance beams from photoinjectors. The main difficulty foreseen is control of emittance oscillations in the beam in this scheme, which can be naturally considered as an extension of the emittance compensation process at moderate energies. This paper presents two scenarios in which velocity bunching, combined with emittance control, is to play a role in nascent projects. The first is termed ballistic bunching, where the changing of relative particle velocities and positions occur in distinct regions, a short high gradient linac, and a drift length. This scenario is discussed in the context of the proposed ORION photoinjector. Simulations are used to explore the relationship between the degree of bunching, and the emittance compensation process. Experimental measurements performed at the UCLA Neptune Laboratory of the surprisingly robust bunching process, as well as accompanying deleterious transverse effects, are presented. An unanticipated mechanism for emittance growth in bends for highly momentum chirped beam was identified and studied in these experiments. The second scenario may be designated as phase space rotation, and corresponds closely to the recent proposal of Ferrario and Serafini. Its implementation for the compression of the electron beam pulse length in the PLEIADES inverse Compton scattering (ICS experiment at LLNL is discussed. It is shown in simulations that optimum compression may be obtained by manipulation of the phases in low gradient traveling wave accelerator sections. Measurements of the bunching and emittance control achieved in such an implementation at PLEIADES, as well as aspects of the use of velocity-bunched beam directly

  12. State orthogonality, boson bunching parameter and bosonic enhancement factor

    International Nuclear Information System (INIS)

    Marchewka, A.; Granot, E.

    2016-01-01

    Bosons bunching is the tendency of bosons to bunch together with respect to distinguishable particles. It is emphasized that the bunching parameter β = p_B/p_D, i.e. the ratio between the probability to measure 2 bosons and 2 distinguishable particles at the same state, is a constant of motion and depends only on the overlap between the initial wavefunctions. This ratio is equal to β = 2/(1 + l"2), where l is the overlap integral between the initial wavefunctions. That is, only when the initial wavefunctions are orthogonal this ratio is equal to 2, however, this bunching ratio can be reduced to 1, when the two wavefunctions are identical. This simple equation explains the experimental evidences of a beam splitter. A straightforward conclusion is that by measuring the local bunching parameter β (at any point in space and time) it is possible to evaluate a global parameter l (the overlap between the initial wavefunctions). The bunching parameter is then generalized to arbitrary number of particles, and in an analogy to the two-particles scenario, the well-known bosonic enhancement appears only when all states are orthogonal

  13. Bunches of random cross-correlated sequences

    International Nuclear Information System (INIS)

    Maystrenko, A A; Melnik, S S; Pritula, G M; Usatenko, O V

    2013-01-01

    The statistical properties of random cross-correlated sequences constructed by the convolution method (likewise referred to as the Rice or the inverse Fourier transformation) are examined. We clarify the meaning of the filtering function—the kernel of the convolution operator—and show that it is the value of the cross-correlation function which describes correlations between the initial white noise and constructed correlated sequences. The matrix generalization of this method for constructing a bunch of N cross-correlated sequences is presented. Algorithms for their generation are reduced to solving the problem of decomposition of the Fourier transform of the correlation matrix into a product of two mutually conjugate matrices. Different decompositions are considered. The limits of weak and strong correlations for the one-point probability and pair correlation functions of sequences generated by the method under consideration are studied. Special cases of heavy-tailed distributions of the generated sequences are analyzed. We show that, if the filtering function is rather smooth, the distribution function of generated variables has the Gaussian or Lévy form depending on the analytical properties of the distribution (or characteristic) functions of the initial white noise. Anisotropic properties of statistically homogeneous random sequences related to the asymmetry of a filtering function are revealed and studied. These asymmetry properties are expressed in terms of the third- or fourth-order correlation functions. Several examples of the construction of correlated chains with a predefined correlation matrix are given. (paper)

  14. The LHC Transverse Coupled-Bunch Instability

    CERN Document Server

    Mounet, Nicolas; Métral, Elias

    In this thesis, the problem of the transverse coupled-bunch instabilities created by the Large Hadron Collider (LHC) beam-coupling impedance, that can possibly limit the machine operation, is addressed thanks to several new theories and tools. A rather complete vision of the problem is proposed here, going from the calculation of the impedances and wake functions of individual machine elements, to the beam dynamics study. Firstly, new results are obtained in the theory of the beam-coupling impedance for an axisymmetric two-dimensional structure, generalizing Zotter's theories, and a new general theory is derived for the impedance of an infinite flat two-dimensional structure. Then, a new approach has been found to compute the wake functions from such analytically obtained beam-coupling impedances, over-coming limitations that could be met with standard discrete Fourier transform procedures. Those results are then used to obtain an impedance and wake function model of the LHC, based on the (resistive-) wall im...

  15. Virtual photon impulse of bunch, beampipe response, coherent RF Beamstrahlung; and BEPC bunch length, BES jam, virtual acceleration

    International Nuclear Information System (INIS)

    Jing Shen

    1993-01-01

    A brief EEE view of signal QED is presented. The research has been concentrated on the virtual photon modes of ultra relativistic shock wave in a bunch-beampipe system, and real photon modes of Coherent RF Beamstrahlung CRFB. Physically, the virtual photons emitted by a bunch were treated as a travelling pseudo wave packet in a flight coaxial cavity constructed by bunch-wakefield core and beampipe. Mathematically, it is a boundary solution of shock wave excited by ultra relativistic impulse of bunch. The new modes of solution: VTA, VTEM, VTM, VLE are virtual photon packets and RTE, RTM, RTEM are real photon modes of CRFB. By these results the author measured and corrected BEPC bunch length from signals of : (1) TOF reference of BES, (2) BPM of BEPC, (3) Colliding CRFB of BEPC - BES coupling signal, as well as (4) the ordinary method of Synchrotron Radiation. All results of the measured bunch lengths are in accordance with the design length of BEPC, and were verified by the BES data of vertex reconstruction of hadron events. The author also found that CRFB is the unknown jam source of BES electronics. VLE virtual photons can accelerate particles

  16. A 40 MHz Bunch by Bunch Intensity Measurement for the CERN SPS and LHC

    CERN Document Server

    Jakob, H; Jones, R; Jensen, L

    2003-01-01

    A new acquisition system has been developed to allow the measurement of the individual intensity of each bunch in a 40MHz bunch train. Such a system will be used for the measurement of LHC type beams after extraction from the CERN-PS right through to the dump lines of the CERN-LHC. The method is based on integrating the analogue signal supplied by a Fast Beam Current Transformer at a frequency of 40MHz. This has been made possible with the use of a fast integration ASIC developed by the University of Clermont-Ferrand, France, for the LHC-b pre-shower detector. The output of the integrator is digitised using a 12-bit ADC and fed into a Digital Acquisition Board (DAB) that was originally developed by TRIUMF, Canada, for use in the LHC orbit system. A full system set-up was commissioned during 2002 in the CERN-SPS, and following its success will now be extended in 2003 to cover the PS to SPS transfer lines and the new TT40 LHC extraction channel.

  17. Fast polycrystalline CdTe detectors for bunch-by-bunch luminosity monitoring in the LHC

    CERN Document Server

    Brambilla, A; Jolliot, M; Bravin, E

    2008-01-01

    The luminosity at the four interaction points of the Large Hadron Collider (LHC) must be continuously monitored in order to provide an adequate tool for the control and optimisation of beam parameters. Polycrystalline cadmium telluride (CdTe) detectors have previously been tested, showing their high potential to fulfil the requirements of luminosity measurement in the severe environment of the LHC interaction regions. Further, the large signal yield and the fast response time should allow bunch-by-bunch measurement of the luminosity at 40 MHz with high accuracy. Four luminosity monitors with two rows of five polycrystalline CdTe detectors each have been fabricated and will be installed at both sides of the low-luminosity interaction points ALICE and LHC-b. A detector housing was specially designed to meet the mechanical constraints in the LHC. A series of elementary CdTe detectors were fabricated and tested, of which 40 were selected for the luminosity monitors. A sensitivity of 104 electrons per minimum ioni...

  18. Gamma Irradiation Effects on Oil Palm (Elaies Guineensis) Pollen Viability, Fruits and Bunch Formations

    International Nuclear Information System (INIS)

    Aida Nazlyn Nazari; Azhar Mohamad; Shuhaimi Shamsuddin

    2014-01-01

    Assessing performance and genetic diversity of the wild material of oil palm is important for understanding genetic structure of natural oil palm populations towards improvement of the crops. This information is important for oil palm breeding programs, and also for continued ex-situ conservation of the germplasm and breeding program in Malaysia. Mutation induction is one of the alternative ways in creating variants for selection in the breeding program. In this study, evaluation on the effect of irradiated pollen towards pollen viability, bunches formation and no. of parthenocarpic fruits were conducted. Series of acute gamma radiation at dose 0, 10, 20, 40, 50, 100, 200, 300, 500, 100 and 2000 Gy were exposed to Elaies guineensis pollen. Increasing level of irradiation higher than 200 Grays (Gy) affects pollen viability based on the 12 consecutive days observation evaluated in situ conditions. Besides, at this level of irradiation (> 200 Gy), the pollen tube formation were disrupted and subsequently unable the pollen to reach the ovule which cause the embryo to aborted and contributed to the formation of parthenocarpic fruits and rotten bunches. These observations suggested that at low levels of irradiation (< 200 Gy) may damage only part of the generative nucleus while maintaining its capacity to fertilise the egg cells and lead to hybridization. (author)

  19. Inductive reasoning.

    Science.gov (United States)

    Hayes, Brett K; Heit, Evan; Swendsen, Haruka

    2010-03-01

    Inductive reasoning entails using existing knowledge or observations to make predictions about novel cases. We review recent findings in research on category-based induction as well as theoretical models of these results, including similarity-based models, connectionist networks, an account based on relevance theory, Bayesian models, and other mathematical models. A number of touchstone empirical phenomena that involve taxonomic similarity are described. We also examine phenomena involving more complex background knowledge about premises and conclusions of inductive arguments and the properties referenced. Earlier models are shown to give a good account of similarity-based phenomena but not knowledge-based phenomena. Recent models that aim to account for both similarity-based and knowledge-based phenomena are reviewed and evaluated. Among the most important new directions in induction research are a focus on induction with uncertain premise categories, the modeling of the relationship between inductive and deductive reasoning, and examination of the neural substrates of induction. A common theme in both the well-established and emerging lines of induction research is the need to develop well-articulated and empirically testable formal models of induction. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website. Copyright © 2010 John Wiley & Sons, Ltd.

  20. Sensitivity Analysis for the CLIC Damping Ring Inductive Adder

    CERN Document Server

    Holma, Janne

    2012-01-01

    The CLIC study is exploring the scheme for an electron-positron collider with high luminosity and a nominal centre-of-mass energy of 3 TeV. The CLIC pre-damping rings and damping rings will produce, through synchrotron radiation, ultra-low emittance beam with high bunch charge, necessary for the luminosity performance of the collider. To limit the beam emittance blow-up due to oscillations, the pulse generators for the damping ring kickers must provide extremely flat, high-voltage pulses. The specifications for the extraction kickers of the CLIC damping rings are particularly demanding: the flattop of the output pulse must be 160 ns duration, 12.5 kV and 250 A, with a combined ripple and droop of not more than ±0.02 %. An inductive adder allows the use of different modulation techniques and is therefore a very promising approach to meeting the specifications. PSpice has been utilised to carry out a sensitivity analysis of the predicted output pulse to the value of both individual and groups of circuit compon...

  1. Teacher induction

    NARCIS (Netherlands)

    Beijaard, D.; Buitink, J.; Kessels, C.; Peterson, P.; Baker, E.; McGraw, B.

    2010-01-01

    Teacher induction programs are intended to support the professional development of beginning teachers and thereby contribute to the reduction of teacher attrition during the early teaching years. Teacher induction programs are often based upon a deficit model with a focus on the better organization

  2. Simple method for generating adjustable trains of picosecond electron bunches

    Directory of Open Access Journals (Sweden)

    P. Muggli

    2010-05-01

    Full Text Available A simple, passive method for producing an adjustable train of picosecond electron bunches is demonstrated. The key component of this method is an electron beam mask consisting of an array of parallel wires that selectively spoils the beam emittance. This mask is positioned in a high magnetic dispersion, low beta-function region of the beam line. The incoming electron beam striking the mask has a time/energy correlation that corresponds to a time/position correlation at the mask location. The mask pattern is transformed into a time pattern or train of bunches when the dispersion is brought back to zero downstream of the mask. Results are presented of a proof-of-principle experiment demonstrating this novel technique that was performed at the Brookhaven National Laboratory Accelerator Test Facility. This technique allows for easy tailoring of the bunch train for a particular application, including varying the bunch width and spacing, and enabling the generation of a trailing witness bunch.

  3. Superthermal photon bunching in terms of simple probability distributions

    Science.gov (United States)

    Lettau, T.; Leymann, H. A. M.; Melcher, B.; Wiersig, J.

    2018-05-01

    We analyze the second-order photon autocorrelation function g(2 ) with respect to the photon probability distribution and discuss the generic features of a distribution that results in superthermal photon bunching [g(2 )(0 ) >2 ]. Superthermal photon bunching has been reported for a number of optical microcavity systems that exhibit processes such as superradiance or mode competition. We show that a superthermal photon number distribution cannot be constructed from the principle of maximum entropy if only the intensity and the second-order autocorrelation are given. However, for bimodal systems, an unbiased superthermal distribution can be constructed from second-order correlations and the intensities alone. Our findings suggest modeling superthermal single-mode distributions by a mixture of a thermal and a lasinglike state and thus reveal a generic mechanism in the photon probability distribution responsible for creating superthermal photon bunching. We relate our general considerations to a physical system, i.e., a (single-emitter) bimodal laser, and show that its statistics can be approximated and understood within our proposed model. Furthermore, the excellent agreement of the statistics of the bimodal laser and our model reveals that the bimodal laser is an ideal source of bunched photons, in the sense that it can generate statistics that contain no other features but the superthermal bunching.

  4. Anomalous length of electron bunches as an instability threshold

    International Nuclear Information System (INIS)

    Messerschmid, E.; Month, M.

    1976-01-01

    A mechanism for the anomalous length of electron bunches, based on the existence of a ''fast'' longitudinal instability, is proposed. The equilibrium length is obtained by requiring that the growth rate be sufficiently larger than the rate of synchrotron oscillations. The theory is used to describe the bunch length data for SPEAR at 1.5 GeV. The low voltage and/or high current regime is dominated by a set of ''low'' frequency, low Q resonators [e.g., f = 320 MHz, Δf(fwhm) = 130 MHz]. To fit the observations in the high voltage and/or low current regime, a high frequency, low Q impedance is required (e.g., f = 3.8 GHz, Δf = 1.0 GHz). The mechanism is mediated by the resistive component of the impedance. Thus, there is qualitative agreement with the observed distortion of the bunch tail. This is in contrast to the predictions of the potential well models based on a reactive impedance source. These latter theories yield large distortions of the head of the bunch. The calculated power dissipated in the assumed sources by the given electron bunch is not inconsistent with estimates made for SPEAR

  5. Simulations of Bunch Merging in a Beta Beam Decay Ring

    CERN Document Server

    Heinrich, Daniel Christopher; Chance, Antoine

    2011-01-01

    To further study neutrino oscillation properties a Beta Beam facility has been proposed. Beta decaying ions with high kinetic energy are stored in a storage ring ("Decay Ring") with straight sections to create pure focused (anti) electron neutrino beams. However to reach high sensitivity to neutrino oscillation parameters in the experiment the bunched beam intensity and duty cycle in the DR have to be optimized. The first CERN-based scenario, using 6He and 18Ne as neutrino sources, has been studied using a bunch merging RF scheme. Two RF cavities at different frequencies are used to capture newly injected bunches and then merge them into the stored bunches. It was shown that this scheme could satisfy the requirements on intensity and duty cycle set by the experiment. This merging scheme has now been revised with new simulation software providing new results for 6He and 18Ne. Furthermore bunch merging has been studied for the second CERN-based scenario using 8Li and 8B.

  6. Destructive interferences results in bosons anti bunching: refining Feynman's argument

    Science.gov (United States)

    Marchewka, Avi; Granot, Er'el

    2014-09-01

    The effect of boson bunching is frequently mentioned and discussed in the literature. This effect is the manifestation of bosons tendency to "travel" in clusters. One of the core arguments for boson bunching was formulated by Feynman in his well-known lecture series and has been frequently used ever since. By comparing the scattering probabilities of two bosons and of two distinguishable particles, he concluded: "We have the result that it is twice as likely to find two identical Bose particles scattered into the same state as you would calculate assuming the particles were different" [R.P. Feynman, R.B. Leighton, M. Sands, The Feynman Lectures on Physics: Quantum mechanics (Addison-Wesley, 1965)]. This argument was rooted in the scientific community (see for example [C. Cohen-Tannoudji, B. Diu, F. Laloë, Quantum Mechanics (John Wiley & Sons, Paris, 1977); W. Pauli, Exclusion Principle and Quantum Mechanics, Nobel Lecture (1946)]), however, while this sentence is completely valid, as is proved in [C. Cohen-Tannoudji, B. Diu, F. Laloë, Quantum Mechanics (John Wiley & Sons, Paris, 1977)], it is not a synonym of bunching. In fact, as it is shown in this paper, wherever one of the wavefunctions has a zero, bosons can anti-bunch and fermions can bunch. It should be stressed that zeros in the wavefunctions are ubiquitous in Quantum Mechanics and therefore the effect should be common. Several scenarios are suggested to witness the effect.

  7. Bunch lengthening in the SLC [Stanford Linear Collider] damping rings

    International Nuclear Information System (INIS)

    Bane, K.L.F.

    1990-02-01

    A high level of current dependent bunch lengthening has been observed on the North damping ring of the Stanford Linear Collider (SLC). At currents of 3 x 10 10 this behavior does not appear to degrade the machine's performance significantly. However, at the higher currents that are envisioned for the future one fears that its performance could be greatly degraded due to the phenomenon of bunch lengthening. This was the motivation for the work described in this paper. In this paper we calculate the longitudinal impedance of the damping ring vacuum chamber. More specifically, in this paper we find the response function of the ring to a short Gaussian bunch, which we call the Green function wake. In addition, we try to estimate the relative importance of the different vacuum chamber objects, in order to see how we might reduce the ring impedance. This paper also describes bunch length measurements performed on the North damping ring. We use the Green function wake, discussed above, to compute the bunch lengthening. Then we compare these results with those obtained from the measurements. In addition, we calculate the current dependence of the tune distribution

  8. Beam measurement of the high frequency impedance sources with long bunches in the CERN Super Proton Synchrotron

    Directory of Open Access Journals (Sweden)

    A. Lasheen

    2018-03-01

    Full Text Available Microwave instability in the Super Proton Synchrotron (SPS at CERN is one of the main limitations to reach the requirements for the High Luminosity-LHC project (increased beam intensity by a factor 2. To identify the impedance source responsible of the instability, beam measurements were carried out to probe the SPS impedance. The method presented in this paper relies on measurements of the unstable spectra of single bunches, injected in the SPS with the rf voltage switched off. The modulation of the bunch profile gives information about the main impedance sources driving microwave instability, and is compared to particle simulations using the SPS impedance model to identify the most important contributions. This allowed us to identify the vacuum flanges as the main impedance source for microwave instability in the SPS, and to evaluate possible missing impedance sources.

  9. Beam measurement of the high frequency impedance sources with long bunches in the CERN Super Proton Synchrotron

    Science.gov (United States)

    Lasheen, A.; Argyropoulos, T.; Bohl, T.; Esteban Müller, J. F.; Timko, H.; Shaposhnikova, E.

    2018-03-01

    Microwave instability in the Super Proton Synchrotron (SPS) at CERN is one of the main limitations to reach the requirements for the High Luminosity-LHC project (increased beam intensity by a factor 2). To identify the impedance source responsible of the instability, beam measurements were carried out to probe the SPS impedance. The method presented in this paper relies on measurements of the unstable spectra of single bunches, injected in the SPS with the rf voltage switched off. The modulation of the bunch profile gives information about the main impedance sources driving microwave instability, and is compared to particle simulations using the SPS impedance model to identify the most important contributions. This allowed us to identify the vacuum flanges as the main impedance source for microwave instability in the SPS, and to evaluate possible missing impedance sources.

  10. Performance of the transverse coupled-bunch feedback system in the SRRC

    International Nuclear Information System (INIS)

    Hsu, K.T.; Kuo, C.C.; Kuo, C.H.; Lin, K.K.; Ueng, T.S.; Weng, W.T.

    1996-01-01

    A transverse feedback system has been implemented and commissioned in the SRRC storage ring to suppress transverse coupled-bunch oscillations of the electron beam. The system includes transverse oscillation detectors, notch filter, baseband quadrature processing circuitry, power amplifiers, and kickers. To control a large number of transverse coupled-bunch modes, the system is broad-band, bunch-by- bunch in nature. Because the system is capable of bunch-by-bunch correction, it can also be useful for suppressing instabilities introduced by ions. The sextupole strength was then reduced to improve dynamic aperture and hence lifetime of the storage ring

  11. Acceleration, current amplification and emittance in MBE-4, an experimental beam induction linear accelerator for heavy ions

    International Nuclear Information System (INIS)

    Warwick, A.I.; Gough, D.E.; Keefe, D.; Meuth, H.

    1988-10-01

    We report on the implementation of a second schedule of acceleration and current amplification in MBE-4. Control of the beam current within the bunch is improved over that in the first schedule by the addition of several small amplitude induction pulsers to compensate for acceleration errors and to control the ends of the bunch. Measurements of the longitudinal and transverse emittance are presented. 5 refs., 3 figs., 1 tab

  12. Acceleration, current amplification and emittance in MBE-4, an experimental multiple beam induction linear accelerator for heavy ions

    International Nuclear Information System (INIS)

    Warwick, A.I.; Gough, D.E.; Keefe, D.; Meuth, H.

    1989-01-01

    The authors report on the implementation of a second schedule of acceleration and current amplification in MBE-4. Control of the beam current within the bunch is improved over that in the first schedule by the addition of several small amplitude induction pulsers to compensate for acceleration errors and to control the ends of the bunch. Measurements of the longitudinal and transverse emittance are presented. 5 refs., 3 figs., 1 tab

  13. Fast cooling of bunches in compton storage rings*

    CERN Document Server

    Bulyak, E; Zimmermann, F

    2011-01-01

    We propose an enhancement of laser radiative cooling by utilizing laser pulses of small spatial and temporal dimensions, which interact only with a fraction of an electron bunch circulating in a storage ring. We studied the dynamics of such electron bunch when laser photons scatter off the electrons at a collision point placed in a section with nonzero dispersion. In this case of ‘asymmetric cooling’, the stationary energy spread is much smaller than under conditions of regular scattering where the laser spot size is larger than the electron beam; and the synchrotron oscillations are damped faster. Coherent oscillations of large amplitude may be damped within one synchrotron period, so that this method can support the rapid successive injection of many bunches in longitudinal phase space for stacking purposes. Results of extensive simulations are presented for the performance optimization of Compton gamma-ray sources and damping rings.

  14. Improved Bunch Splitting for the 75ns LHC Beam

    CERN Document Server

    Damerau, H

    2011-01-01

    The 75ns variant was added to the PS arsenal of LHC-type beams by adapting the 20MHz cavity used to produce the 25 and 50ns variants to operate at a switchable 13MHz. This permitted splitting from harmonic 14 to 28, but at a cost in adiabaticity compared with the h=2142 splitting of the other two cases. Consequently, a delicate empirical optimization was necessary to bring the 75ns beam inside specification. More recently the speed at which the bunches, once fully distinct, are moved apart has been revisited and further optimization achieved. As a by-product, deliberately degrading the splitting by moving the bunches apart too quickly led to sufficient coherent motion in the resultant bunch pair to permit a voltage calibration of the 13MHz cavity by means of the influence on convergence of the rf voltage input into the iterative algorithm of the Tomoscope [1,2].

  15. Enhanced coherent undulator radiation from bunched electron beams

    International Nuclear Information System (INIS)

    Berryman, K.W.; Crosson, E.R.; Ricci, K.N.; Smith, T.I.

    1996-01-01

    When energetic bunches of electrons traverse an undulator field, they can spontaneously emit radiation both coherently and incoherently. Although it has generally been assumed that undulator radiation is incoherent at wavelengths short compared to the longitudinal size of the electron bunch, several recent observations have proved this assumption false. Furthermore, the appearance of coherent radiation is often accompanied by a significant increase in radiated power. Here we report observations of strongly enhanced coherent spontaneous radiation together with direct measurements, using transition radiation techniques, of the electron distributions responsible for the coherent emission. We also report demonstrated enhancements in the predicted spontaneous radiated power by as much as 6x10 4 using electron bunch compression. copyright 1996 American Institute of Physics

  16. Thresholds of a bunched beam longitudinal instability in proton synchrotrons

    International Nuclear Information System (INIS)

    Balbekov, V.I.; Ivanov, S.V.

    1986-01-01

    The formulas and graphs for calculating instability thresholds arising during the interaction of a bunched proton beam with narrow-band resonator are given. The instabilities of three types with oscillations of a definite multipolarity, oscillations of some bound multipoles and with microwave oscillations arising as a result of addition of a great number of multipoles. The analysis of the above data shows that the increase of oscillations nonlinearity is accompanied by the growth of instability threshold only in the zone of separated and weakly bound multipoles. The increase of spread of synchrotron frequencies reduces the zone separated multipoles owing to which the microwave bunch instability can be caused by more and more low-frequency resonators. In the microwave zone practically there is no stabilizing effect of synchrotron frequencies spread. The instability threshold of the bunched beam now - where exceeds the microwave level

  17. Fast-extraction modulators for Los Alamos Scientific LaboratorY Proton Storage Ring

    International Nuclear Information System (INIS)

    Nunnally, W.C.; Hudgings, D.W.; Sarjeant, W.J.

    1980-01-01

    The development of a short-bunch mode fast-extraction modulator for the LASL proton storage ring has made necessary the design and development of a resonant transformer charging circuit and the design of a new FIB line circuit to provide bipolar pulse outputs with low prepulse, postpulse, and an optimum high-voltage switch environments. The systems are now being developed to operate reliably at the high-average powers required. The short-bunch mode fast-extraction modulator prototype is presently operating. The initial construction of the long-bunch mode fast-extraction modulator prototype is under way, with results expected within the year

  18. A waveguide overloaded cavity as longitudinal kicker for the DA{Phi}NE bunch-by-bunch feedback system

    Energy Technology Data Exchange (ETDEWEB)

    Gallo, A; Boni, R; Ghigo, A; Marcellini, F; Serio, M; Zobov, M [Instituto Nazionale de Fisica Nucleare, Frascati (Italy). Lab. Nazionale di Frascati

    1996-08-01

    The multibunch operation of DA{Phi}NE calls for a very efficient feedback system to damp the coupled-bunch longitudinal instabilities. A collaboration program among SLAC, LBL and LNF laboratories on this subject led to the development of a time domain, digital system based on digital signal processors that has been already successfully tested at ALS. The feedback chain ends with the longitudinal kicker, an electromagnetic structure capable of transferring the proper energy correction to each bunch. A cavity kicker for the DA{Phi}NE bunch-by-bunch longitudinal feedback system based on a pill-box loaded by six waveguides has been designed and a full-scale aluminium prototype has been fabricated at LNF. Both simulations and measurements have shown a peak shunt impedance of about 750 ohm and a bandwidth of about 220 MHz. The large shunt impedance allows to economize on the costly feedback power. Moreover, the damping waveguides drastically reduce the device HOM longitudinal and transverse impedances. One cavity pre ring will be sufficient to operate the machine up to 30 bunches while a second device per ring together with a feedback power improvement will be necessary to reach the ultimate current. (G.T.)

  19. Higher-order photon bunching in a semiconductor microcavity

    DEFF Research Database (Denmark)

    Assmann, M.; Veit, F.; Bayer, M.

    2009-01-01

    Quantum mechanically indistinguishable particles such as photons may show collective behavior. Therefore, an appropriate description of a light field must consider the properties of an assembly of photons instead of independent particles. We have studied multiphoton correlations up to fourth order...... in the single-mode emission of a semiconductor microcavity in the weak and strong coupling regimes. The counting statistics of single photons were recorded with picosecond time resolution, allowing quantitative measurement of the few-photon bunching inside light pulses. Our results show bunching behavior...

  20. Electron bunch length measurement with a wakefield radiation decelerator

    Directory of Open Access Journals (Sweden)

    Weiwei Li

    2014-03-01

    Full Text Available In this paper, we propose a novel method to measure the electron bunch length with a dielectric wakefield radiation (DWR decelerator which is composed of two dielectric-lined waveguides (DLWs and an electron spectrometer. When an electron beam passes through a DLW, the DWR is excited which leads to an energy loss of the electron beam. The energy loss is found to be largely dependent on the electron bunch length and can be easily measured by an electron spectrometer which is essential for a normal accelerator facility. Our study shows that this method has a high resolution and a great simplicity.

  1. Transient analysis of a bunched beam free electron laser

    International Nuclear Information System (INIS)

    Wang, J.M.; Yu, L.H.

    1985-01-01

    The problem of the bunched beam operation of a free electron laser was studied. Assuming the electron beam to be initially monoenergetic, the Maxwell-Vlasov equations describing the system reduce to a third order partial differential equation for the envelope of the emitted light. The Green's function corresponding to an arbitrary shape of the electron bunch, which describes the transient behavior of the system, is obtained. The Green's function was used to discuss the start up problem as well as the power output and the power specrum of a self-amplified spontaneous emission

  2. Modelling and measurements of bunch profiles at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Papadopoulou, S. [Crete U.; Antoniou, F. [Liverpool U.; Argyropoulos, T. [CERN; Fitterer, M. [Fermilab; Hostettler, M. [CERN; Papaphilippou, Y. [CERN

    2017-07-20

    The bunch profiles in the LHC are often observed to be non-Gaussian, both at Flat Bottom (FB) and Flat Top (FT) energies. Especially at FT, an evolution of the tail population in time is observed. In this respect, the Monte-Carlo Software for IBS and Radiation effects (SIRE) is used to track different types of beam distributions. The impact of the distribution shape on the evolution of bunch characteristics is studied. The results are compared with observations from the LHC Run 2 data.

  3. Optical plasma torch electron bunch generation in plasma wakefield accelerators

    Directory of Open Access Journals (Sweden)

    G. Wittig

    2015-08-01

    Full Text Available A novel, flexible method of witness electron bunch generation in plasma wakefield accelerators is described. A quasistationary plasma region is ignited by a focused laser pulse prior to the arrival of the plasma wave. This localized, shapeable optical plasma torch causes a strong distortion of the plasma blowout during passage of the electron driver bunch, leading to collective alteration of plasma electron trajectories and to controlled injection. This optically steered injection is more flexible and faster when compared to hydrodynamically controlled gas density transition injection methods.

  4. Refinements to longitudinal, single bunch, coherent instability theory

    Energy Technology Data Exchange (ETDEWEB)

    Koscielniak, S R

    1995-06-01

    For the case of a bunched beam confined to a quadratic potential well, we demonstrate the necessity for considering mode-coupling to correctly obtain the threshold current for the d.c. instability. Further we find the effect upon growth rate and coherent tune shift of evaluating the impedance at a complex frequency. For the case of a bunched beam confined to a cosine potential well, we give an exact analytic expression for the dispersion integral, and calculate (with no approximations), the stability diagram for the Robinson instability taking into account Landau damping. This paper comprises extracts from a lengthy internal report. (author). 2 refs., 4 figs.

  5. Emittance Growth during Bunch Compression in the CTF-II

    Energy Technology Data Exchange (ETDEWEB)

    Raubenheimer, Tor O

    1999-02-26

    Measurements of the beam emittance during bunch compression in the CLIC Test Facility (CTF-II) are described. The measurements were made with different beam charges and different energy correlations versus the bunch compressor settings which were varied from no compression through the point of full compression and to over-compression. Significant increases in the beam emittance were observed with the maximum emittance occurring near the point of full (maximal) compression. Finally, evaluation of possible emittance dilution mechanisms indicate that coherent synchrotron radiation was the most likely cause.

  6. Design of the ALS transverse coupled-bunch feedback system

    International Nuclear Information System (INIS)

    Barry, W.; Byrd, J.M.; Corlett, J.N.; Hinkson, J.; Johnson, J.; Lambertson, G.R.; Fox, J.D.

    1993-05-01

    Calculations of transverse coupled bunch growth rates in the Advanced Light Source (ALS), a 1.5 GeV electron storage ring for producing synchrotron radiation, indicate the need for damping via a transverse feedback (TFB) system. We present the design of such a system. The maximum bunch frequency is 500 MHz, requiring that the FB system have a broadband response of at least 250 MHz. We described, in detail, the choice of broadband components such as kickers, pickups, power amplifiers, and electronics

  7. Evolving bunch and retardation in the impedance formalism

    International Nuclear Information System (INIS)

    Warnock, Robert; Venturini, Marco

    2003-01-01

    The usual expression for the longitudinal wake field in terms of the impedance is exact only for the model in which the source of the field is a rigid bunch. To account for a deforming bunch one has to invoke the complete impedance, a function of both wave number and frequency. A computation of the corresponding wake field would be expensive, since it would involve integrals over frequency and time in addition to the usual sum over wave number. We treat the problem of approximating this field in an example of current interest, the case of coherent synchrotron radiation (CSR) in the presence of shielding by the vacuum chamber

  8. Cancellation Effects in CSR Induced Bunch Transverse Dynamics in Bends

    International Nuclear Information System (INIS)

    Li, R.

    2002-01-01

    The partial cancellation between the effect of centrifugal space charge force on transverse bunch dynamics and the potential energy effect has been a long-standing controversial issue in the study of coherent synchrotron radiation (CSR) induced bunch dynamics in bends. In this paper, we clarify our definition of the ''centrifugal space charge force,'' and discuss the meaning of the ''cancellation effect'' and its general application. We further use simulation to demonstrate the cancellation in both steady state and transient regimes, and show the behavior of the effective transverse force

  9. Acceleration of electrons by the wake field of proton bunches

    International Nuclear Information System (INIS)

    Ruggiero, A.G.

    1986-01-01

    This paper discusses a novel idea to accelerate low-intensity bunches of electrons (or positrons) by the wake field of intense proton bunches travelling along the axis of a cylindrical rf structure. Accelerating gradients in excess of 100 MeV/m and large ''transformer ratios'', which allow for acceleration of electrons to energies in the TeV range, are calculated. A possible application of the method is an electron-positron linear collider with luminosity of 10 33 cm -2 s -1 . The relatively low cost and power consumption of the method is emphasized

  10. Phase II study of induction chemotherapy with TPF followed by radioimmunotherapy with Cetuximab and intensity-modulated radiotherapy (IMRT in combination with a carbon ion boost for locally advanced tumours of the oro-, hypopharynx and larynx - TPF-C-HIT

    Directory of Open Access Journals (Sweden)

    Mavtratzas Athanasios

    2011-05-01

    Full Text Available Abstract Background Long-term locoregional control in locally advanced squamous cell carcinoma of the head and neck (SCCHN remains challenging. While recent years have seen various approaches to improve outcome by intensification of treatment schedules through introduction of novel induction and combination chemotherapy regimen and altered fractionation regimen, patient tolerance to higher treatment intensities is limited by accompanying side-effects. Combined radioimmunotherapy with cetuximab as well as modern radiotherapy techniques such as intensity-modulated radiotherapy (IMRT and carbon ion therapy (C12 are able to limit toxicity while maintaining treatment effects. In order to achieve maximum efficacy with yet acceptable toxicity, this sequential phase II trial combines induction chemotherapy with docetaxel, cisplatin, and 5-FU (TPF followed by radioimmunotherapy with cetuximab as IMRT plus carbon ion boost. We expect this approach to result in increased cure rates with yet manageable accompanying toxicity. Methods/design The TPF-C-HIT trial is a prospective, mono-centric, open-label, non-randomized phase II trial evaluating efficacy and toxicity of the combined treatment with IMRT/carbon ion boost and weekly cetuximab in 50 patients with histologically proven locally advanced SCCHN following TPF induction chemotherapy. Patients receive 24 GyE carbon ions (8 fractions and 50 Gy IMRT (2.0 Gy/fraction in combination with weekly cetuximab throughout radiotherapy. Primary endpoint is locoregional control at 12 months, secondary endpoints are disease-free survival, progression-free survival, overall survival, acute and late radiation effects as well as any adverse events of the treatment as well as quality of life (QoL analyses. Discussion The primary objective of TPF-C-HIT is to evaluate efficacy and toxicity of cetuximab in combination with combined IMRT/carbon ion therapy following TPF induction in locally advanced SCCHN. Trial Registration

  11. Bunch-shape monitor for a picosecond single-bunch beam of a 35 MeV electron linear accelerator

    International Nuclear Information System (INIS)

    Hosono, Yoneichi; Nakazawa, Masaharu; Iguchi, Tetsuo

    1995-01-01

    A non-interactive-type bunch-shape and beam intensity monitor for a 35 MeV electron linear accelerator (linac) has been developed. The monitor consists of an electric SMA-type connector and an Al pipe of 50 mm inner diameter. Test measurements of the present monitor have been made under the conditions of the accelerated charges of lower than 27 nC/pulse and the pulse width ranging from 6 to 30 ps (Full Width at Half Maximum). The results show that the present monitor is applicable to bunch-shape measurement of the picosecond single-bunch beam. The monitor output is also found to be proportional to the beam intensity of more than 0.05 nC/pulse. (author)

  12. Flat bunch creation and acceleration: a possible path for the LHC luminosity upgrade

    International Nuclear Information System (INIS)

    Bhat, C.M.

    2009-01-01

    Increasing the collider luminosity by replacing bunches having Gaussian line-charge distribution with flat bunches, but with same beam-beam tune shift at collision, has been studied widely in recent years. But, creation of 'stable' flat bunches (and their acceleration) using a multiple harmonic RF system has not been fully explored. Here, we review our experience with long flat bunches in the barrier RF buckets at Fermilab.We presentsome preliminary results from beam dynamics simulations and recent beam studies in the LHC injectors to create stable flat bunches using double harmonic RF systems. The results deduced from these studies will be used to model the necessary scheme for luminosity upgrade in the LHC. We have also described a viable (and economical) way for creation and acceleration of flat bunches in the LHC. The flat bunch scheme may have many advantages over the LHC baseline scenario, particularly because of the reduced momentum spread of the bunch for increased intensities.

  13. Operation and performance of bunch pre-compression for increased transmission at the SLC

    International Nuclear Information System (INIS)

    Minty, M.G.; Akre, R.; Decker, F.J.; Turner, J.

    1997-11-01

    As the beam currents at the SLC are increased, transverse aperture restrictions in the ring-to-linac transport line (RTL) become increasingly important. The RTL contains a bunch compressor which introduces a large energy variation across the bunch and hence a larger transverse beam size. Since 1994 the compressor amplitude has been operating at higher than design voltage. While advantageous for shaping the bunch distribution, this increased the bunch energy spread and therefore resulted in more beam loss. Moreover, due to current-dependent bunch lengthening in the damping ring, the higher the beam current, the more the current loss. To avoid such losses, the bunch length may be precompressed in the damping ring. Until recently, bunch precompression with high beam currents was not stable. In this paper the authors identify the reasons for the difficulties, describe the changes made to accommodate bunch precompression, and discuss performance aspects after implementation. The estimated increase in current at the interaction point is 15%

  14. The Prototype Inductive Adder With Droop Compensation for the CLIC Kicker Systems

    CERN Document Server

    Holma, J

    2014-01-01

    The Compact Linear Collider (CLIC) study is exploring the scheme for an electron-positron collider with high luminosity and a nominal center-of-mass energy of 3 TeV. The CLIC predamping rings and damping rings (DRs) will produce, through synchrotron radiation, an ultralow emittance beam with high bunch charge. To avoid beam emittance increase, the DR kicker systems must provide extremely flat, high-voltage, pulses. The specifications for the extraction kickers of the DRs are particularly demanding: the flattops of the pulses must be ±12.5 kV with a combined ripple and droop of not more than ±0.02% (±2.5 V). An inductive adder is a very promising approach to meeting the specifications. Recently, a five-layer prototype has been built at CERN. Passive analog modulation has been applied to compensate the voltage droop, for example of the pulse capacitors. The output waveforms of the prototype inductive adder have been compared with predictions of the voltage droop and pulse shape. Conclusions are drawn concern...

  15. Practicing induction:

    DEFF Research Database (Denmark)

    Sprogøe, Jonas; Rohde, Nicolas

    2009-01-01

    We claim that induction potentially triggers both individual and organizational learning and by drawing on practice-based theory we discuss how the interplay between individual and organization, what we call a generative dance, ignites both kinds of learning.......We claim that induction potentially triggers both individual and organizational learning and by drawing on practice-based theory we discuss how the interplay between individual and organization, what we call a generative dance, ignites both kinds of learning....

  16. Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice.

    Science.gov (United States)

    Choi, Sheu-Ran; Roh, Dae-Hyun; Yoon, Seo-Yeon; Kwon, Soon-Gu; Choi, Hoon-Seong; Han, Ho-Jae; Beitz, Alvin J; Lee, Jang-Hern

    2016-12-01

    We have previously shown using a spinal cord injury (SCI) model that gap junctions contribute to the early spread of astrocyte activation in the lumbar spinal cord and that this astrocyte communication plays critical role in the induction of central neuropathic pain. Sigma-1 receptors (Sig-1Rs) have been implicated in spinal astrocyte activation and the development of peripheral neuropathic pain, yet their contribution to central neuropathic pain remains unknown. Thus, we investigated whether SCI upregulates spinal Sig-1Rs, which in turn increase the expression of the astrocytic gap junction protein, connexin 43 (Cx43) leading to the induction of central neuropathic pain. A thoracic spinal cord hemisection significantly increased both astrocyte activation and Cx43 expression in lumbar dorsal horn. Sig-1Rs were also increased in lumbar dorsal horn astrocytes, but not neurons or microglia. Intrathecal injection of an astrocyte metabolic inhibitor (fluorocitrate); a gap junction/hemichannel blocker (carbenoxolone); or a Cx43 mimetic peptide ( 43 Gap26) significantly reduced SCI-induced bilateral below-level mechanical allodynia. Blockade of Sig-1Rs with BD1047 during the induction phase of pain significantly suppressed the SCI-induced development of mechanical allodynia, astrocyte activation, increased expression of Cx43 in both total and membrane levels, and increased association of Cx43 with Sig-1R. However, SCI did not change the expression of oligodendrocyte (Cx32) or neuronal (Cx36) gap junction proteins. These findings demonstrate that SCI activates astrocyte Sig-1Rs leading to increases in the expression of the gap junction protein, Cx43 and astrocyte activation in the lumbar dorsal horn, and ultimately contribute to the induction of bilateral below-level mechanical allodynia. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance.

    Science.gov (United States)

    Edwards, Justin P; Hand, Timothy W; Morais da Fonseca, Denise; Glass, Deborah D; Belkaid, Yasmine; Shevach, Ethan M

    2016-06-01

    Treg cells can secrete latent TGF-β1 (LTGF-β1), but can also utilize an alternative pathway for transport and expression of LTGF-β1 on the cell surface in which LTGF-β1 is coupled to a distinct LTGF-β binding protein termed glycoprotein A repetitions predominant (GARP)/LRRC32. The function of the GARP/LTGF-β1 complex has remained elusive. Here, we examine in vivo the roles of GARP and TGF-β1 in the induction of oral tolerance. When Foxp3(-) OT-II T cells were transferred to wild-type recipient mice followed by OVA feeding, the conversion of Foxp3(-) to Foxp3(+) OT-II cells was dependent on recipient Treg cells. Neutralization of IL-2 in the recipient mice also abrogated this conversion. The GARP/LTGF-β1 complex on recipient Treg cells, but not dendritic cell-derived TGF-β1, was required for efficient induction of Foxp3(+) T cells and for the suppression of delayed hypersensitivity. Expression of the integrin αvβ8 by Treg cells (or T cells) in the recipients was dispensable for induction of Foxp3 expression. Transient depletion of the bacterial flora enhanced the development of oral tolerance by expanding Treg cells with enhanced expression of the GARP/LTGF-β1 complex. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

  18. Observation of the substructure in the electron bunch on the ACO storage ring

    International Nuclear Information System (INIS)

    Bergher, M.; Velghe, M.; Mialocq, J.P.

    1984-09-01

    In the future, one interesting point of the SRFEL at Orsay will be the microtemporal analysis of the laser beam correlated with that of the electron bunch. In a first time, we have only analysed the temporal structure of the electron bunch with an Electrophotonic streak camera. The first results seem to indicate that the bunch is not an homogeneous bunch but presents a substructure. We discuss with details this data

  19. Loss of Landau Damping for Inductive Impedance in a Double RF System

    CERN Document Server

    Argyropoulos, T; Burov, A

    2013-01-01

    In this paper the thresholds of the loss of Landau damping due to the presence of inductive impedance in a single and double harmonic RF systems are determined, both from calculations and particle simulations. A high harmonic RF system, operating in bunch lengthening mode is used in many accelerators with space charge or inductive impedance to reduce the peak line density or stabilize the beam. An analytical approach, based on emerging of the discrete Van Kampen modes, shows that improved stability in a double RF system can be achieved only below some critical value of longitudinal emittance. Above this threshold, a phase shift of more than 15 degrees between the two RF components is proven necessary to stabilize the bunch. These results, confirmed also by particle simulations, now are able to explain observations during the pp operation of the SPS. The thresholds in bunch shortening mode as well as in a single RF case are compared with this regime.

  20. Radial bunch compression : path-length compensation in an rf photoinjector with a curved cathode

    NARCIS (Netherlands)

    Loos, de M.J.; Geer, van der S.B.; Saveliev, Y.M.; Pavlov, V.M.; Reitsma, A.J.W.; Wiggins, S.M.; Rodier, J.; Garvey, T.; Jaroszynski, D.A.

    2006-01-01

    Electron bunch lengthening due to space-charge forces in state-of-the-art rf photoinjectors limits the minimum bunch length attainable to several hundreds of femtoseconds. Although this can be alleviated by increasing the transverse dimension of the electron bunch, a larger initial radius causes

  1. On the single bunch longitudinal collective effects in electron storage rings

    CERN Document Server

    Gao, J

    2002-01-01

    After giving an analytical expression for the single bunch short range wake potential of a storage ring, we have discussed separately the roles of linear and nonlinear terms of the Taylor expansion of the wake potential on the bunch longitudinal motion. The equations describing bunch lengthening and increase in energy spread are established. Applications to different operating machines are made.

  2. Acceleration of a trailing positron bunch in a plasma wakefield accelerator

    International Nuclear Information System (INIS)

    Doche, A.; Beekman, C.; Corde, S.

    2017-01-01

    High gradients of energy gain and high energy efficiency are necessary parameters for compact, cost-efficient and high-energy particle colliders. Plasma Wakefield Accelerators (PWFA) offer both, making them attractive candidates for next-generation colliders. Here in these devices, a charge-density plasma wave is excited by an ultra-relativistic bunch of charged particles (the drive bunch). The energy in the wave can be extracted by a second bunch (the trailing bunch), as this bunch propagates in the wake of the drive bunch. While a trailing electron bunch was accelerated in a plasma with more than a gigaelectronvolt of energy gain, accelerating a trailing positron bunch in a plasma is much more challenging as the plasma response can be asymmetric for positrons and electrons. We report the demonstration of the energy gain by a distinct trailing positron bunch in a plasma wakefield accelerator, spanning nonlinear to quasi-linear regimes, and unveil the beam loading process underlying the accelerator energy efficiency. A positron bunch is used to drive the plasma wake in the experiment, though the quasi-linear wake structure could as easily be formed by an electron bunch or a laser driver. Finally, the results thus mark the first acceleration of a distinct positron bunch in plasma-based particle accelerators.

  3. Palm oil fresh fruit bunch ripeness grading identification using color ...

    African Journals Online (AJOL)

    This research investigates the ripeness grading identification of the palm oil FFB using color features that are color histogram, color moment and color correlogram. Palm is harvested during the optimum stage of its ripeness since it improves the FFB oil quality and quantity. Harvesting wrong bunches decreases the oil ...

  4. BUNCHED BEAM STOCHASTIC COOLING SIMULAITONS AND COMPARISON WITH DATA

    Energy Technology Data Exchange (ETDEWEB)

    BLASKIEWICZ,M.; BRENNAN, J.M.

    2007-09-10

    With the experimental success of longitudinal, bunched beam stochastic cooling in RHIC it is natural to ask whether the system works as well as it might and whether upgrades or new systems are warranted. A computer code, very similar to those used for multi-particle coherent instability simulations, has been written and is being used to address these questions.

  5. Simulations of Merging Helion Bunches on the AGS Injection Porch

    Energy Technology Data Exchange (ETDEWEB)

    Gardner, C. J. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.

    2014-08-29

    During the setup of helions for the FY2014 RHIC run it was discovered that the standard scheme for merging bunches on the AGS injection porch required an injection kicker pulse shorter than what was available. To overcome this difficulty, K. Zeno proposed and developed an interesting and unusual alternative which uses RF harmonic numbers 12, 4, 2 (rather than the standard 8, 4, 2) to merge 8 helion bunches into 2. In this note we carry out simulations that illustrate how the alternative scheme works and how it compares with the standard scheme. This is done in Sections 13 and 14. A scheme in which 6 bunches are merged into 1 is simulated in Section 15. This may be useful if more helions per merged bunch are needed in future runs. General formulae for the simulations are given in Sections 9 through 12. For completeness, Sections 1 through 8 give a derivation of the turn-by-turn equations of longitudinal motion at constant magnetic field. The derivation is based on the work of MacLachlan. The reader may wish to skip over these Sections and start with Section 9.

  6. Simulations of Merging Helion Bunches on the AGS Injection Porch

    International Nuclear Information System (INIS)

    Gardner, C. J.

    2014-01-01

    During the setup of helions for the FY2014 RHIC run it was discovered that the standard scheme for merging bunches on the AGS injection porch required an injection kicker pulse shorter than what was available. To overcome this difficulty, K. Zeno proposed and developed an interesting and unusual alternative which uses RF harmonic numbers 12, 4, 2 (rather than the standard 8, 4, 2) to merge 8 helion bunches into 2. In this note we carry out simulations that illustrate how the alternative scheme works and how it compares with the standard scheme. This is done in Sections 13 and 14. A scheme in which 6 bunches are merged into 1 is simulated in Section 15. This may be useful if more helions per merged bunch are needed in future runs. General formulae for the simulations are given in Sections 9 through 12. For completeness, Sections 1 through 8 give a derivation of the turn-by-turn equations of longitudinal motion at constant magnetic field. The derivation is based on the work of MacLachlan. The reader may wish to skip over these Sections and start with Section 9.

  7. Operational experience with nanocoulomb bunch charges in the Cornell photoinjector

    Directory of Open Access Journals (Sweden)

    Adam Bartnik

    2015-08-01

    Full Text Available Characterization of 9–9.5 MeV electron beams produced in the dc-gun based Cornell photoinjector is given for bunch charges ranging from 20 pC to 2 nC. Comparison of the measured emittances and longitudinal current profiles to optimized 3D space charge simulations yields excellent agreement for bunch charges up to 1 nC when the measured laser distribution is used to generate initial particle distributions in simulation. Analysis of the scaling of the measured emittance with bunch charge shows that the emittance scales roughly as the square root of the bunch charge up to 300 pC, above which the trend becomes linear. These measurements demonstrate that the Cornell photoinjector can produce cathode emittance dominated beams meeting the emittance and peak current specifications for next generation free electron lasers operating at high repetition rate. In addition, the 1 and 2 nC results are relevant to the electron ion collider community.

  8. Tax Bunching, Income Shifting and Self-employment

    DEFF Research Database (Denmark)

    le Maire, Christian Daniel; Schjerning, Bertel

    shifting was neglected in this case, we would conclude that taxable incomes were highly sensitive to changes in marginal tax rates. We show, however, that more than half of the observed bunching in taxable income for the self-employed is driven by intertemporal income shifting, implying a structural...

  9. Tax Bunching, Income Shifting and Self-employment

    DEFF Research Database (Denmark)

    le Maire, Christian Daniel; Schjerning, Bertel

    2013-01-01

    was neglected in this case, we would estimate a taxable income elasticity in the range of 0.43-0.53 and conclude that taxable incomes were highly sensitive to changes in marginal tax rates. We show, however, that more than half of the bunching in taxable income is driven by intertemporal income shifting...

  10. LHC Report: 1,033 bunches per beam and counting

    CERN Multimedia

    Jorg Wenninger for the LHC team

    2015-01-01

    Following the second technical stop, the first beams were injected into the LHC in the early evening of Saturday, 5 September. About ten days later, the machine was operated with around 1,000 bunches per beam.    Evolution of the stored energy per LHC beam, over time.   The first step after a technical stop consists of running through a full LHC cycle, from injection to collisions and beam dump, with a low-intensity bunch (“probe”) to check all machine settings and equipment. This is followed by a series of collimation and absorber validation tests at different points in the LHC cycle. Low-intensity beams – typically the equivalent of three nominal bunches (3 x 1011 protons) – are expanded transversely or longitudinally, or de-bunched to verify that the collimators and absorbers are correctly intercepting lost particles. The techniques for those validations have been progressively improved, and t...

  11. Generation of slow positron beam and beam bunching

    International Nuclear Information System (INIS)

    Azuma, O.; Satoh, T.; Shitoh, M.; Kaneko, N.; Kawaratani, T.; Hara, O.

    1994-01-01

    Two items are described in this report. One is about the outline of our slow positron beam system, which has been fabricated as a commercial prototype. The other is about the calculation result of positron beam bunching, which will be an additional function to the system. (author)

  12. State orthogonality, boson bunching parameter and bosonic enhancement factor

    Science.gov (United States)

    Marchewka, Avi; Granot, Er'el

    2016-04-01

    It is emphasized that the bunching parameter β ≡ p B / p D , i.e. the ratio between the probability to measure two bosons and two distinguishable particles at the same state, is a constant of motion and depends only on the overlap between the initial wavefunctions. This ratio is equal to β = 2 / (1 + I 2), where I is the overlap integral between the initial wavefunctions. That is, only when the initial wavefunctions are orthogonal this ratio is equal to 2, however, this bunching ratio can be reduced to 1, when the two wavefunctions are identical. This simple equation explains the experimental evidences of a beam splitter. A straightforward conclusion is that by measuring the local bunching parameter β (at any point in space and time) it is possible to evaluate a global parameter I (the overlap between the initial wavefunctions). The bunching parameter is then generalized to arbitrary number of particles, and in an analogy to the two-particles scenario, the well-known bosonic enhancement appears only when all states are orthogonal.

  13. Theory of longitudinal instability for bunched electron and proton beams

    International Nuclear Information System (INIS)

    Ruggiero, A.G.

    1977-01-01

    A discussion is given of an original approach for the treatment of the longitudinal stability of high-intensity proton and electron bunches. The general analysis is divided in three steps. First, a search is made for a stationary bunch distribution which is matched to the external rf forces as well as to the current dependent induced fields. The existence of such distribution is questioned. Second, the stability of the stationary solution is checked by applying a small perturbation and observing whether this is initially damped or not. At this point a stability condition is derived in terms of current, surrounding impedance and bunch size. In the last step one should question what happens to the beam in case the stability condition is not satisfied. The problem here is the determination of the final bunch configuration. The originality of the approach stays in the combination of the three steps. All previous theories either consider only the first step or combine the second and third ones but disregard the first

  14. Colossal photon bunching in quasiparticle-mediated nanodiamond cathodoluminescence

    Science.gov (United States)

    Feldman, Matthew A.; Dumitrescu, Eugene F.; Bridges, Denzel; Chisholm, Matthew F.; Davidson, Roderick B.; Evans, Philip G.; Hachtel, Jordan A.; Hu, Anming; Pooser, Raphael C.; Haglund, Richard F.; Lawrie, Benjamin J.

    2018-02-01

    Nanoscale control over the second-order photon correlation function g(2 )(τ ) is critical to emerging research in nonlinear nanophotonics and integrated quantum information science. Here we report on quasiparticle control of photon bunching with g(2 )(0 ) >45 in the cathodoluminescence of nanodiamond nitrogen vacancy (NV0) centers excited by a converged electron beam in an aberration-corrected scanning transmission electron microscope. Plasmon-mediated NV0 cathodoluminescence exhibits a 16-fold increase in luminescence intensity correlated with a threefold reduction in photon bunching compared with that of uncoupled NV0 centers. This effect is ascribed to the excitation of single temporally uncorrelated NV0 centers by single surface plasmon polaritons. Spectrally resolved Hanbury Brown-Twiss interferometry is employed to demonstrate that the bunching is mediated by the NV0 phonon sidebands, while no observable bunching is detected at the zero-phonon line. The data are consistent with fast phonon-mediated recombination dynamics, a conclusion substantiated by agreement between Bayesian regression and Monte Carlo models of superthermal NV0 luminescence.

  15. Study of the electromagnetic characteristics of multiple HTSPPT modules based on the configuration of toroidal structure for inductive pulsed power supply

    Science.gov (United States)

    Zhang, Cunshan; Zheng, Xinxin; Li, Haitao; Li, Zhenmei; Zhang, Tao; Jiao, Can

    2018-04-01

    High temperature superconducting pulsed power transformer (HTSPPT) is an important device for pulsed power supplies. It consists of a superconducting primary and a normal conducting secondary, which is used for energy storage and current amplification. The critical current density, the energy storage, and the coupling coefficient are three main performance indexes. They are affected by the geometry parameters of HTSPPT modules, such as the height and the width of the superconducting coils. In addition, the hoop stress of the HTSPPT coils is limited by the maximum tensile strength of high temperature superconducting (HTS) tapes. In this paper, Bi-2223/Ag HTS tapes are selected as the wire of primary inductor and the toroidal structure model is selected for multiple HTSPPT modules. The relationships between the geometry parameters of HTSPPT modules and the electrical performance are studied.

  16. Electro-optic methods for longitudinal bunch diagnostics at FLASH

    International Nuclear Information System (INIS)

    Steffen, B.R.

    2007-07-01

    Precise measurements of the temporal profile of sub-picosecond electron bunches are of high interest for the optimization and operation of VUV and X-ray free electron lasers. In this thesis, the shortest electro-optic signals measured so far for electron bunch diagnostics are presented, reaching a time resolution of better than 50 fs (rms). The e ects that introduce signal distortions and limit the time resolution are studied in numerical simulations for different electro-optic detection materials and techniques. The time resolution is mainly limited by lattice resonances of the electro-optic crystal. Electro-optic signals as short as 54 fs (rms) are obtained with gallium phosphide (GaP) crystals in a crossed polarizer detection scheme using temporally resolved electro-optic detection. Measuring near crossed polarization, where the electro-optic signal is proportional to the velocity field of the relativistic electron bunch, the shortest obtained signal width is 70 fs (rms). The electro-optic signals are compared to electron bunch shapes that are measured simultaneously with a transverse deflecting structure with 20 fs resolution. Numerical simulations using the bunch shapes as determined with the transverse deflecting cavity as input data are in excellent agreement with electro-optical signals obtained with GaP, both for temporally and spectrally resolved measurements. In the case of zinc telluride (ZnTe) the observed signals are slightly broader and significantly smaller than expected from simulations. These discrepancies are probably due to the poor optical quality of the available ZnTe crystals. (orig.)

  17. Preservation of low slice emittance in bunch compressors

    Directory of Open Access Journals (Sweden)

    S. Bettoni

    2016-03-01

    Full Text Available Minimizing the dilution of the electron beam emittance is crucial for the performance of accelerators, in particular for free electron laser facilities, where the length of the machine and the efficiency of the lasing process depend on it. Measurements performed at the SwissFEL Injector Test Facility revealed an increase in slice emittance after compressing the bunch even for moderate compression factors. The phenomenon was experimentally studied by characterizing the dependence of the effect on beam and machine parameters relevant for the bunch compression. The reproduction of these measurements in simulation required the use of a 3D beam dynamics model along the bunch compressor that includes coherent synchrotron radiation. Our investigations identified transverse effects, such as coherent synchrotron radiation and transverse space charge as the sources of the observed emittance dilution, excluding other effects, such as chromatic effects on single slices or spurious dispersion. We also present studies, both experimental and simulation based, on the effect of the optics mismatch of the slices on the variation of the slice emittance along the bunch. After a corresponding reoptimization of the beam optics in the test facility we reached slice emittances below 200 nm for the central slices along the longitudinal dimension with a moderate increase up to 300 nm in the head and tail for a compression factor of 7.5 and a bunch charge of 200 pC, equivalent to a final current of 150 A, at about 230 MeV energy.

  18. Electro-optic methods for longitudinal bunch diagnostics at FLASH

    Energy Technology Data Exchange (ETDEWEB)

    Steffen, B.R.

    2007-07-15

    Precise measurements of the temporal profile of sub-picosecond electron bunches are of high interest for the optimization and operation of VUV and X-ray free electron lasers. In this thesis, the shortest electro-optic signals measured so far for electron bunch diagnostics are presented, reaching a time resolution of better than 50 fs (rms). The e ects that introduce signal distortions and limit the time resolution are studied in numerical simulations for different electro-optic detection materials and techniques. The time resolution is mainly limited by lattice resonances of the electro-optic crystal. Electro-optic signals as short as 54 fs (rms) are obtained with gallium phosphide (GaP) crystals in a crossed polarizer detection scheme using temporally resolved electro-optic detection. Measuring near crossed polarization, where the electro-optic signal is proportional to the velocity field of the relativistic electron bunch, the shortest obtained signal width is 70 fs (rms). The electro-optic signals are compared to electron bunch shapes that are measured simultaneously with a transverse deflecting structure with 20 fs resolution. Numerical simulations using the bunch shapes as determined with the transverse deflecting cavity as input data are in excellent agreement with electro-optical signals obtained with GaP, both for temporally and spectrally resolved measurements. In the case of zinc telluride (ZnTe) the observed signals are slightly broader and significantly smaller than expected from simulations. These discrepancies are probably due to the poor optical quality of the available ZnTe crystals. (orig.)

  19. Ion acceleration in modulated electron beams

    International Nuclear Information System (INIS)

    Bonch-Osmolovskij, A.G.; Dolya, S.N.

    1977-01-01

    A method of ion acceleration in modulated electron beams is considered. Electron density and energy of their rotational motion are relatively low. However the effective ion-accelerating field is not less than 10 MeV/m. The electron and ion numbers in an individual bunch are also relatively small, although the number of produced bunches per time unit is great. Some aspects of realization of the method are considered. Possible parameters of the accelerator are given. At 50 keV electron energy and 1 kA beam current a modulation is realized at a wave length of 30 cm. The ion-accelerating field is 12 MeV/m. The bunch number is 2x10 3 in one pulse at a gun pulse duration of 2 μs. With a pulse repetition frequency of 10 2 Hz the number of accelerated ions can reach 10 13 -10 14 per second

  20. Application of Chemical Genomics to Plant-Bacteria Communication: A High-Throughput System to Identify Novel Molecules Modulating the Induction of Bacterial Virulence Genes by Plant Signals.

    Science.gov (United States)

    Vandelle, Elodie; Puttilli, Maria Rita; Chini, Andrea; Devescovi, Giulia; Venturi, Vittorio; Polverari, Annalisa

    2017-01-01

    The life cycle of bacterial phytopathogens consists of a benign epiphytic phase, during which the bacteria grow in the soil or on the plant surface, and a virulent endophytic phase involving the penetration of host defenses and the colonization of plant tissues. Innovative strategies are urgently required to integrate copper treatments that control the epiphytic phase with complementary tools that control the virulent endophytic phase, thus reducing the quantity of chemicals applied to economically and ecologically acceptable levels. Such strategies include targeted treatments that weaken bacterial pathogens, particularly those inhibiting early infection steps rather than tackling established infections. This chapter describes a reporter gene-based chemical genomic high-throughput screen for the induction of bacterial virulence by plant molecules. Specifically, we describe a chemical genomic screening method to identify agonist and antagonist molecules for the induction of targeted bacterial virulence genes by plant extracts, focusing on the experimental controls required to avoid false positives and thus ensuring the results are reliable and reproducible.

  1. Mutation induction and neoplastic transformation in human and human-hamster hybrid cells: dependence on photon energy and modulation in the low-dose range

    Energy Technology Data Exchange (ETDEWEB)

    Frankenberg, D.; Frankenberg-Schwager, M.; Garg, I.; Pralle, E. [Abt. Klin. Strahlenbiologie und Klin. Strahlenphysik, Universitaet Goettingen, Goettingen (Germany); Uthe, D.; Greve, B.; Severin, E.; Goehde, W. [Institut fuer Strahlenbiologie, Universitaet Muenster, Munster (Germany)

    2002-09-01

    Mutation induction in the HPRT gene of human fibroblasts after irradiation with mammography-like 29 kVp or 200 kVp x-rays shows radiohypersensitivity for doses smaller than {approx}0.5 Gy. Similarly, mutation induction in the CD 59 gene on human chromosome 11 in A{sub L} cells shows radiohypersensitivity for doses smaller than {approx}0.5 Gy after exposure to 200 kVp x-rays, but not after irradiation with low-filtered 30 kVp x-rays. The RBE values of 29 and 30 kVp x-rays relative to 200 kVp x-rays are strongly dose dependent. For neoplastic transformation of human hybrid (CGL1) cells after irradiation with 29 or 200 kVp x-rays or {sup 60}Co gamma rays a linear-quadratic dose relationship was observed with RBE values of approximately four and eight for mammography relative to 200 kVp x-rays and {sup 60}Co gamma rays, respectively. (author)

  2. A fifth harmonic rf bunch monitor for the ANL-APS electron linac

    International Nuclear Information System (INIS)

    Nassiri, A.; Grelick, A.

    1993-01-01

    The function of a fifth harmonic (14.28 GHz) bunch monitor is to provide a signal which is proportional to the electron beam bunch size. The monitoring of the rf power signal at 14.28 GHz enables the operator to optimize the rf bunching of the beam at the end of the first accelerating section where the full bunching has been formed and remains mainly constant in size throughout the rest of the electron linac. A modified version of the SLAC original bunch monitor has been fabricated and its rf properties measured. This paper describes the design and the initial measurement results

  3. Bunch rotation tests at SPS flat top for the AWAKE experiment

    CERN Document Server

    Argyropoulos, T; Bohl, T; Esteban Müller, J F; Petrenko, A; Shaposhnikova, E; Timko, H

    2013-01-01

    This note summarises the results of two MDs on bunch rotation at SPS flat top. The first MD was carried out on 11th July 2012 with the Q26 optics, while the second MD on the 30th October 2012 used the Q20 optics. To obtain a short bunch length, which is important for the plasma wake-field acceleration project AWAKE, the bunches have been rotated in longitudinal phase space on the SPS flat top. The aim of the MDs was to obtain first estimates of what bunch length, intensity, and transverse emittances - which are crucial for the project - can be achieved for high-intensity single bunches.

  4. A fifth harmonic RF bunch monitor for the ANL-APS electron linac

    International Nuclear Information System (INIS)

    Nassiri, A.; Grelick, A.

    1993-01-01

    The function of a fifth harmonic (14.28 GHz) bunch monitor is to provide a signal which is proportional to the electron beam bunch size. The monitoring of the rf power signal at 14.28 GHz enables the operator to optimize the rf bunching of the beam at the end of the first accelerating section where the full bunching has been formed and remains mainly constant in size throughout the rest of the electron linac. A modified version of the SLAC original bunch monitor has been fabricated and its rf properties measured. This paper describes the design and the initial measurements results

  5. High-Precision Phenotyping of Grape Bunch Architecture Using Fast 3D Sensor and Automation

    Directory of Open Access Journals (Sweden)

    Florian Rist

    2018-03-01

    Full Text Available Wine growers prefer cultivars with looser bunch architecture because of the decreased risk for bunch rot. As a consequence, grapevine breeders have to select seedlings and new cultivars with regard to appropriate bunch traits. Bunch architecture is a mosaic of different single traits which makes phenotyping labor-intensive and time-consuming. In the present study, a fast and high-precision phenotyping pipeline was developed. The optical sensor Artec Spider 3D scanner (Artec 3D, L-1466, Luxembourg was used to generate dense 3D point clouds of grapevine bunches under lab conditions and an automated analysis software called 3D-Bunch-Tool was developed to extract different single 3D bunch traits, i.e., the number of berries, berry diameter, single berry volume, total volume of berries, convex hull volume of grapes, bunch width and bunch length. The method was validated on whole bunches of different grapevine cultivars and phenotypic variable breeding material. Reliable phenotypic data were obtained which show high significant correlations (up to r2 = 0.95 for berry number compared to ground truth data. Moreover, it was shown that the Artec Spider can be used directly in the field where achieved data show comparable precision with regard to the lab application. This non-invasive and non-contact field application facilitates the first high-precision phenotyping pipeline based on 3D bunch traits in large plant sets.

  6. High-Precision Phenotyping of Grape Bunch Architecture Using Fast 3D Sensor and Automation.

    Science.gov (United States)

    Rist, Florian; Herzog, Katja; Mack, Jenny; Richter, Robert; Steinhage, Volker; Töpfer, Reinhard

    2018-03-02

    Wine growers prefer cultivars with looser bunch architecture because of the decreased risk for bunch rot. As a consequence, grapevine breeders have to select seedlings and new cultivars with regard to appropriate bunch traits. Bunch architecture is a mosaic of different single traits which makes phenotyping labor-intensive and time-consuming. In the present study, a fast and high-precision phenotyping pipeline was developed. The optical sensor Artec Spider 3D scanner (Artec 3D, L-1466, Luxembourg) was used to generate dense 3D point clouds of grapevine bunches under lab conditions and an automated analysis software called 3D-Bunch-Tool was developed to extract different single 3D bunch traits, i.e., the number of berries, berry diameter, single berry volume, total volume of berries, convex hull volume of grapes, bunch width and bunch length. The method was validated on whole bunches of different grapevine cultivars and phenotypic variable breeding material. Reliable phenotypic data were obtained which show high significant correlations (up to r² = 0.95 for berry number) compared to ground truth data. Moreover, it was shown that the Artec Spider can be used directly in the field where achieved data show comparable precision with regard to the lab application. This non-invasive and non-contact field application facilitates the first high-precision phenotyping pipeline based on 3D bunch traits in large plant sets.

  7. Vitamin E γ-Tocotrienol Inhibits Cytokine-Stimulated NF-κB Activation by Induction of Anti-Inflammatory A20 via Stress Adaptive Response Due to Modulation of Sphingolipids.

    Science.gov (United States)

    Wang, Yun; Park, Na-Young; Jang, Yumi; Ma, Averil; Jiang, Qing

    2015-07-01

    NF-κB plays a central role in pathogenesis of inflammation and cancer. Many phytochemicals, including γ-tocotrienol (γTE), a natural form of vitamin E, have been shown to inhibit NF-κB activation, but the underlying mechanism has not been identified. In this study, we show that γTE inhibited cytokine-triggered activation of NF-κB and its upstream regulator TGF-β-activated kinase-1 in murine RAW 264.7 macrophages and primary bone marrow-derived macrophages. In these cells, γTE induced upregulation of A20, an inhibitor of NF-κB. Knockout of A20 partially diminished γTE's anti-NF-κB effect, but γTE increased another NF-κB inhibitor, Cezanne, in A20(-/-) cells. In search of the reason for A20 upregulation, we found that γTE treatment increased phosphorylation of translation initiation factor 2, IκBα, and JNK, indicating induction of endoplasmic reticulum stress. Liquid chromatography-tandem mass spectrometry analyses revealed that γTE modulated sphingolipids, including enhancement of intracellular dihydroceramides, sphingoid bases in de novo synthesis of the sphingolipid pathway. Chemical inhibition of de novo sphingolipid synthesis partially reversed γTE's induction of A20 and the anti-NF-κB effect. The importance of dihydroceramide increase is further supported by the observation that C8-dihydroceramide mimicked γTE in upregulating A20, enhancing endoplasmic reticulum stress, and attenuating TNF-triggered NF-κB activation. Our study identifies a novel anti-NF-κB mechanism where A20 is induced by stress-induced adaptive response as a result of modulation of sphingolipids, and it demonstrates an immunomodulatory role of dihydrocermides. Copyright © 2015 by The American Association of Immunologists, Inc.

  8. CSR Interaction for a 2D Energy-Chirped Bunch on a General Orbit

    International Nuclear Information System (INIS)

    Li, Rui

    2009-01-01

    When an electron bunch with initial linear energy chirp traverses a bunch compression chicane, the bunch interacts with itself via coherent synchrotron radiation (CSR) and space charge force. The effective longitudinal CSR force for such kind of 2D bunch on a circular orbit has been analyzed earlier (1). In this paper, we present the analytical results of the effective longitudinal CSR force for a 2D energy-chirped bunch going through a general orbit, which includes the entrance and exit of a circular orbit. In particular, we will show the behavior of the force in the last bend of a chicane when the bunch is under extreme compression. This is the condition when bifurcation of bunch phase space occurs in many CSR measurements. (1) R. Li, Phys. Rev. ST Accel. Beams 11, 024401 (2008)

  9. Creation and Storage of Long and Flat Bunches in the LHC

    CERN Document Server

    Damerau, H

    2005-01-01

    To maximize the luminosity of the Large Hadron Collider (LHC), the collision of particle bunches with a uniform longitudinal particle density is considered for a future upgrade. The benefits of such bunches and their generation by means of special longitudinal beam manipulations are presented in this report. Three possible options are analyzed with respect to their potential luminosity gain at the beam-beam limit: short rectangular bunches held by radio frequency (RF) harmonics using multiples of the nominal RF frequency of 400.8MHz, long and flat bunches held by multiples of 40.08MHz, and so-called superbunches, confined by barrier buckets. The comparison of the three different approaches shows that flat bunches, with an intermediate bunch length of the order of several meters, are capable of producing a comparable luminosity to superbunches, while avoiding most of their inherent disadvantages. Possible schemes to create the bunches with uniform line density are studied and a longitudinal manipulation to com...

  10. Induction practice -

    DEFF Research Database (Denmark)

    Rohde, Nicolas; Sprogøe, Jonas

    2007-01-01

    that induction potentially triggers both individual and organizational learning and by drawing on practice-based theory we discuss how the interplay between individual and the organization, what we call agenerative dance, ignites both kinds of learning. We focus on and describe the interplay , ignites both kinds...

  11. Properties of Trapped Electron Bunches in a Plasma Wakefield Accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Kirby, Neil; /SLAC

    2009-10-30

    Plasma-based accelerators use the propagation of a drive bunch through plasma to create large electric fields. Recent plasma wakefield accelerator (PWFA) experiments, carried out at the Stanford Linear Accelerator Center (SLAC), successfully doubled the energy for some of the 42 GeV drive bunch electrons in less than a meter; this feat would have required 3 km in the SLAC linac. This dissertation covers one phenomenon associated with the PWFA, electron trapping. Recently it was shown that PWFAs, operated in the nonlinear bubble regime, can trap electrons that are released by ionization inside the plasma wake and accelerate them to high energies. These trapped electrons occupy and can degrade the accelerating portion of the plasma wake, so it is important to understand their origins and how to remove them. Here, the onset of electron trapping is connected to the drive bunch properties. Additionally, the trapped electron bunches are observed with normalized transverse emittance divided by peak current, {epsilon}{sub N,x}/I{sub t}, below the level of 0.2 {micro}m/kA. A theoretical model of the trapped electron emittance, developed here, indicates that the emittance scales inversely with the square root of the plasma density in the non-linear 'bubble' regime of the PWFA. This model and simulations indicate that the observed values of {epsilon}{sub N,x}/I{sub t} result from multi-GeV trapped electron bunches with emittances of a few {micro}m and multi-kA peak currents. These properties make the trapped electrons a possible particle source for next generation light sources. This dissertation is organized as follows. The first chapter is an overview of the PWFA, which includes a review of the accelerating and focusing fields and a survey of the remaining issues for a plasma-based particle collider. Then, the second chapter examines the physics of electron trapping in the PWFA. The third chapter uses theory and simulations to analyze the properties of the trapped

  12. The HIV-1 Tat protein modulates CD4 expression in human T cells through the induction of miR-222.

    Science.gov (United States)

    Orecchini, Elisa; Doria, Margherita; Michienzi, Alessandro; Giuliani, Erica; Vassena, Lia; Ciafrè, Silvia Anna; Farace, Maria Giulia; Galardi, Silvia

    2014-01-01

    Several cellular microRNAs show substantial changes in expression during HIV-1 infection and their active role in the viral life cycle is progressively emerging. In the present study, we found that HIV-1 infection of Jurkat T cells significantly induces the expression of miR-222. We show that this induction depends on HIV-1 Tat protein, which is able to increase the transcriptional activity of NFkB on miR-222 promoter. Moreover, we demonstrate that miR-222 directly targets CD4, a key receptor for HIV-1, thus reducing its expression. We propose that Tat, by inducing miR-222 expression, complements the CD4 downregulation activity exerted by other viral proteins (i.e., Nef, Vpu, and Env), and we suggest that this represents a novel mechanism through which HIV-1 efficiently represses CD4 expression in infected cells.

  13. The HIV-1 Tat protein modulates CD4 expression in human T cells through the induction of miR-222

    Science.gov (United States)

    Orecchini, Elisa; Doria, Margherita; Michienzi, Alessandro; Giuliani, Erica; Vassena, Lia; Ciafrè, Silvia Anna; Farace, Maria Giulia; Galardi, Silvia

    2014-01-01

    Several cellular microRNAs show substantial changes in expression during HIV-1 infection and their active role in the viral life cycle is progressively emerging. In the present study, we found that HIV-1 infection of Jurkat T cells significantly induces the expression of miR-222. We show that this induction depends on HIV-1 Tat protein, which is able to increase the transcriptional activity of NFkB on miR-222 promoter. Moreover, we demonstrate that miR-222 directly targets CD4, a key receptor for HIV-1, thus reducing its expression. We propose that Tat, by inducing miR-222 expression, complements the CD4 downregulation activity exerted by other viral proteins (i.e., Nef, Vpu, and Env), and we suggest that this represents a novel mechanism through which HIV-1 efficiently represses CD4 expression in infected cells. PMID:24717285

  14. Induction of DNA damage in γ-irradiated nuclei stripped of nuclear protein classes: differential modulation of double-strand break and DNA-protein crosslink formation

    International Nuclear Information System (INIS)

    Xue, L.-Y.; Friedman, L.R.; Oleinick, N.L.; Chiu, S.-M.

    1994-01-01

    The influence of chromatin proteins on the induction of DNA double-strand breaks (dsb) and DNA-protein crosslinks (dpc) by γ-radiation was investigated. Low molecular weight non-histone proteins and classes of histones were extracted with increasing concentrations of NaC1, whereas nuclear matrix proteins were not extractable even by 2.0 M NACl. The yield of dsb increased with progressive removal of proteins from chromatin. The data support our previous conclusion that nuclear matrix protein rather than the majority of the histones are the predominant substrates for dpc production, although the involvement of a subset of tightly bound histones (H3 and H4) has not been excluded. This finding demonstrates that chromatin proteins can differentially modify the yield of two types of radiation-induced DNA lesions. (author)

  15. Inductive energy storage commutator

    International Nuclear Information System (INIS)

    Gavrilov, I.M.

    1987-01-01

    An inductive energy storage commutator is described. The value of commutated current is up to 800 A, the voltage amplitude in the load is up to 50 kV, the working frequency is equal to 1-50 Hz, the commutated power is up to 40 MW. The commutating device comprises of the first stage commutator having two in-series connected modules of the BTSV - 800/235 high-voltage thyristor unit, the second stage commutator containing three GMI-43A parallel connected powerful pulsed triodes, a commutating capacitor, an induction coil, two supplementary high-voltage thyristor keys (20 in-series connected thyristors T2-300 (13 class)), load, control pulse shapers, thyristor keys, power supply

  16. Repetitive Bunches from RF-Photo Gun Radiate Coherently

    CERN Document Server

    Van der Geer, C A J; Van der Geer, S B

    2004-01-01

    We consider to feed the laser wake field accelerator of the alpha-X project by a train of low charge pancake electron bunches to reduce undesired expansion due to space-charge forces. To this purpose the photo excitation laser of the rf-injector is split into a train of sub-pulses, such that each of the produced electron bunches falls into a successive ponderomotive well of the plasma accelerator. This way the total accelerated charge is not reduced. The repetitive photo gun can be tested, at low energy, by connecting it directly to the undulator and monitoring the radiation. The assertions are based on the results of new GPT simulations.

  17. Bunch lengthening and related effects in SPEAR II

    International Nuclear Information System (INIS)

    Wilson, P.B.; Servranckx, R.; Sabersky, A.P.; Gareyte, J.; Fischer, G.E.; Chao, A.W.; Donald, M.H.R.

    1977-03-01

    In recent years, electron storage ring designers have become aware of the problems caused by the interaction of short, high current bunches with their environment. Important effects are: (1) energy loss can cause local overheating of chamber components; (2) additional rf power is required due to overall energy loss; (3) the increased energy spread requires increased aperture; (4) destructive instabilities could occur. Anomalous bunch lengthening and energy spread, the spectroscopy of longitudinal modes and the shift of synchronous phase were simultaneously measured in order to study the dynamics of the interaction. From the data obtained at SPEAR II one is led to a model of coupling impedance which should be useful in the design of any electron ring

  18. MD210 Note: Creation of Hollow Bunches in the PSB

    CERN Document Server

    Oeftiger, Adrian; Findlay, Alan James; Hancock, Steven; Rumolo, Giovanni; CERN. Geneva. ATS Department

    2016-01-01

    MD210 aims for the creation of longitudinally hollow bunches in the CERN PS Booster. The first three sessions have been carried out using the radial loop feedback system in order to drive the beam on a dipolar parametric resonance (instead of the phase loop). It has been found that the damping by the phase loop inhibits the excitation of the resonance to a major extent. The hollow distributions generated under these circumstances fail to reach a satisfying bunching factor. Nonetheless, proving the principally successful application of this technique to the PS Booster promises good results once the phase loop system supports trim functions. The approach, actions and detailed results of the first three MD sessions are presented in this paper.

  19. Preliminary Study on Two Possible Bunch Compression Schemes at NLCTA

    International Nuclear Information System (INIS)

    Sun, Yipeng

    2011-01-01

    In this paper, two possible bunch compression configurations are proposed and evaluated by numerical simulation in the Next Linear Collider Test Accelerator (NLCTA) at SLAC. A bunch compression ratio up to 20 could be achieved under a perfect condition, without consideration for the timing jitter and other error sources. The NLCTA is a test accelerator built at SLAC, which is approximately 42 meters long and composed of X-band acceleration structures. The main aim of building NLCTA is to develop and demonstrate the X-band rf acceleration technologies for the next generation linear collider, with a relatively high acceleration gradient between 50 MV/m and 100 MV/m. The current operation configuration of NLCTA features a thermionic-cathode electron gun at its starting point which generates an electron beam with an energy of 5 MeV. This is followed by a roughly 1.5 meter long X-band acceleration structure which boosts the electron beam energy to 60 MeV. Then there is a four-dipole magnetic chicane which is 6 meters long and provides a first order longitudinal dispersion of R 56 = -73mm. Next the electron beam passes by several matching quadrupoles and can be accelerated further to 120 MeV through another one-meter-long X-band acceleration structure. After that, there are three small chicanes downstream, with a total first order longitudinal dispersion of R 56 = -10mm. A sketch of the main components of NLCTA is shown in Figure 1, where the total length of this accelerator is 45 meters. Free Electron Lasers (FELs), proposed by J. Madey and demonstrated for the first time at Stanford University in 1970s (2) (3), use the lasing of relativistic electron beam traveling through a magnetic undulator, which can reach high power and can be widely tunable in wavelength. Linac based FEL source can provide sufficient brightness, and a short X-ray wavelength down to angstrom scale, which promises in supporting wide range of research experiments. In order to have an electron beam

  20. Longitudinal coupled-bunch instability studies in the PS

    CERN Document Server

    Damerau, H

    2017-01-01

    The main longitudinal limitation for LHC-type beams inthe PS are coupled-bunch instabilities. A dedicated proto-typefeedbacksystemusingaFinemetcavityasalongitudinalkicker has been installed. Extensive tests with beam havebeen performed to explore the intensity reach with this feed-back. The maximum intensity with nominal longitudinalemittance at PS extraction has been measured, as well as theemittance required to keep the beam longitudinally stableat the design intensity for the High-Luminosity LHC (HL-LHC). A higher-harmonic cavity is a complementary op-tion to extend the intensity reach beyond the capabilities ofthe coupled-bunch feedback. Preliminary machine develop-ment (MD) studies operating one20MHzor one40MHzRF system as a higher harmonic at the flat-top indicate thebeneficial effect on longitudinal beam stability

  1. Electron Bunch Length Measurement for LCLS at SLAC

    International Nuclear Information System (INIS)

    Zelazny, M.; Allison, S.; Chevtsov, Sergei; Emma, P.; Kotturi, K.d.; Loos, H.; Peng, S.; Rogind, D.; Straumann, T.

    2007-01-01

    At Stanford Linear Accelerator Center (SLAC) a Bunch Length Measurement system has been developed to measure the length of the electron bunch for its new Linac Coherent Light Source (LCLS). This destructive measurement uses a transverse-mounted RF deflector (TCAV) to vertically streak the electron beam and an image taken with an insertable screen and a camera. The device control software was implemented with the Experimental Physics and Industrial Control System (EPICS) toolkit. The analysis software was implemented in Matlab(trademark) using the EPICS/Channel Access Interface for Scilab(trademark) and Matlab(trademark) (labCA). This architecture allowed engineers and physicists to develop and integrate their control and analysis without duplication of effort

  2. Emittance preservation during bunch compression with a magnetized beam

    Energy Technology Data Exchange (ETDEWEB)

    Stratakis, Diktys [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-09-02

    The deleterious effects of coherent synchrotron radiation (CSR) on the phase-space and energy spread of high-energy beams in accelerator light sources can significantly constrain the machine design and performance. In this paper, we present a simple method to preserve the beam emittance by means of using magnetized beams that exhibit a large aspect ratio on their transverse dimensions. The concept is based on combining a finite solenoid field where the beam is generated together with a special optics adapter. Numerical simulations of this new type of beam source show that the induced phase-space density growth can be notably suppressed to less than 1% for any bunch charge. This work elucidates the key parameters that are needed for emittance preservation, such as the required field and aspect ratio for a given bunch charge.

  3. Coherent spontaneous radiation from highly bunched electron beams

    International Nuclear Information System (INIS)

    Berryman, K.W.; Crosson, E.R.; Ricci, K.N.

    1995-01-01

    Coherent spontaneous radiation has now been observed in several FELs, and is a subject of great importance to the design of self-amplified spontaneous emission (SASE) devices. We report observations of coherent spontaneous radiation in both FIREFLY and the mid-infrared FEL at the Stanford Picosecond FEL Center. Coherent emission has been observed at wavelengths as short as 5 microns, and enhancement over incoherent levels by as much as a factor of 4x10 4 has been observed at longer wavelengths. The latter behavior was observed at 45 microns in FIREFLY with short bunches produced by off-peak acceleration and dispersive compression. We present temporal measurements of the highly bunched electron distributions responsible for the large enhancements, using both transition radiation and energy-phase techniques

  4. Single bunch beam breakup in linacs and BNS damping

    International Nuclear Information System (INIS)

    Toyomasu, Takanori

    1991-12-01

    We study a single-bunch beam breakup (BBU) problem by a macro-particle model. We consider both the BBU solution and the Landau damping solution which includes the Balakin-Novokhatsky-Smirnov (BNS) damping. In the BBU solution, we get an analytic solution which includes both the Chao-Richter-Yao solution and the two-particle model solution and which agrees well with simulation. The solution can also be used in a multi-bunch case. In the Landau damping solution, we can be see the mechanism of Landau damping formally and can get some insights into BNS damping. We confirm that a two-particle model criterion for BNS damping is a good one. We expect that the two-particle model criterion is represented by the first order interaction in Landau damping solution of a macro-particle model. (author)

  5. Bio-phenolic resin from oil palm empty fruit bunches

    Science.gov (United States)

    Zakaria, Zuhaili; Zakaria, Sarani; Roslan, Rasidi; Chia, Chin Hua; Jaafar, Sharifah Nabihah Syed; Amran, Umar Adli

    2018-04-01

    Utilization of oil palm empty fruit bunches (EFB) in the production of bio-phenolic resin is an alternative way to reduce the dependency of petroleum-based phenol. In this study, resol type bio-phenolic resin (BPR) was synthesized from EFB fibers using sulfuric acid as the catalyst to produce liquefied empty fruit bunches (LEFB) followed by resinification reaction with formaldehyde in alkaline condition. The SEM image of LEFB residue showed separation of fiber bundles into individual fibers. This indicate that lignin was destroyed during the liquefaction process. The increased of formaldehyde/LEFB molar ratio has resulted an increase of viscosity, solid content and pH of the resin. The obtained FTIR spectra confirmed that functional groups of BPR resins was almost similar with commercial resin.

  6. Bunch-motion feedback for B-factories

    International Nuclear Information System (INIS)

    Lambertson, G.R.

    1992-09-01

    The colliding electron and positron beams in a B-factory must have average current of one ampere or more to produce the required luminosity. The high current interacts with structures in the beam tube to drive strong coupled-bunch (c.b.) instabilities. To suppress these instabilities requires negative feedback of the bunch motions. Beam impedances arising from strong rf cavity modes should first be reduced to make the required feedback damping rate practical and the cost economical. In what follows, control of transverse motions will be discussed first, then longitudinal. We shall use the parameters of the 3.1 GeV ring of PEP-II to illustrate the general requirements

  7. Loss factor for short bunches in azimuthally symmetric tapered structures

    Directory of Open Access Journals (Sweden)

    A. Blednykh

    2010-06-01

    Full Text Available We use the program ECHO to study numerically the loss factor of axisymmetric cavities and collimators with and without tapering. We consider a Gaussian driving bunch of length σ, and structures with inner radius b, outer radius d, cavity gap (or collimator inner length g, and taper length L. In all cases we consider a short bunch with σ≪b. For the untapered structures (L=0, in certain regimes, we describe our numerical results using the known expressions for a step transition and for the diffraction model. In addition, we identify new regimes where gb, we present a phenomenological formula which accurately describes the dependence of the loss factor on the parameters σ, b, d, and L. This formula also holds for a tapered cavity with g>d^{2}/σ and d-b>b.

  8. Laser vacuum acceleration of a relativistic electron bunch

    Energy Technology Data Exchange (ETDEWEB)

    Glazyrin, I V; Karpeev, A V; Kotova, O G; Nazarov, K S [E.I. Zababakhin All-Russian Scientific-Research Institute of Technical Physics, Russian Federal Nuclear Centre, Snezhinsk, Chelyabinsk region (Russian Federation); Bychenkov, V Yu [P N Lebedev Physics Institute, Russian Academy of Sciences, Moscow (Russian Federation)

    2015-06-30

    With regard to the problem of laser acceleration of a relativistic electron bunch we present a scheme of its vacuum acceleration directly by a relativistic intensity laser pulse. The energy of the electron bunch injected into the laser pulse leading edge increases during its coaxial movement to a thin, pulse-reflecting target. The laser-accelerated electrons continue to move free forward, passing through the target. The study of this acceleration scheme in the three-dimensional geometry is verified in a numerical simulation by the particle-in-cell method, which showed that the energy of a part of the electrons can increase significantly compared to the initial one. Restrictions are discussed, which impose limiting values of energy and total charge of accelerated electrons. (superstrong light fields)

  9. Compensating effect of the coherent synchrotron radiation in bunch compressors

    Science.gov (United States)

    Jing, Yichao; Hao, Yue; Litvinenko, Vladimir N.

    2013-06-01

    Typical bunch compression for a high-gain free-electron laser (FEL) requires a large compression ratio. Frequently, this compression is distributed in multiple stages along the beam transport line. However, for a high-gain FEL driven by an energy recovery linac (ERL), compression must be accomplished in a single strong compressor located at the beam line’s end; otherwise the electron beam would be affected severely by coherent synchrotron radiation (CSR) in the ERL’s arcs. In such a scheme, the CSR originating from the strong compressors could greatly degrade the quality of the electron beam. In this paper, we present our design for a bunch compressor that will limit the effect of CSR on the e-beam’s quality. We discuss our findings from a study of such a compressor, and detail its potential for an FEL driven by a multipass ERL developed for the electron-Relativistic Heavy Ion Collider.

  10. Emittance preservation during bunch compression with a magnetized beam

    Energy Technology Data Exchange (ETDEWEB)

    Stratakis, Diktys

    2016-03-01

    The deleterious effects of coherent synchrotron radiation (CSR) on the phase-space and energy spread of high-energy beams in accelerator light sources can significantly constrain the machine design and performance. In this paper, we present a simple method to preserve the beam emittance by means of using magnetized beams that exhibit a large aspect ratio on their transverse dimensions. The concept is based in combining a finite solenoid field where the beam is generated with a special optics adapter. Numerical simulations of this new type of beam source show that the induced phase-space density growth from CSR can be notably suppressed to less than 1% for any bunch charge. This work elucidates the key parameters that are needed for emittance preservation, such as the required field and aspect ratio for a given bunch charge.

  11. Ultrashort electron bunch length measurement with diffraction radiation deflector

    Science.gov (United States)

    Xiang, Dao; Huang, Wen-Hui

    2007-01-01

    In this paper, we propose a novel method to measure electron bunch length with a diffraction radiation (DR) deflector which is composed of a DR radiator and three beam position monitors (BPMs). When an electron beam passes through a metallic aperture which is tilted by 45 degrees with respect to its trajectory, backward DR that propagates perpendicular to the beam’s trajectory is generated which adds a transverse deflection to the beam as a result of momentum conservation. The deflection is found to be largely dependent on the bunch length and could be easily observed with a downstream BPM. Detailed investigations show that this method has wide applicability, high temporal resolution, and great simplicity.

  12. Ultrashort electron bunch length measurement with diffraction radiation deflector

    Directory of Open Access Journals (Sweden)

    Dao Xiang

    2007-01-01

    Full Text Available In this paper, we propose a novel method to measure electron bunch length with a diffraction radiation (DR deflector which is composed of a DR radiator and three beam position monitors (BPMs. When an electron beam passes through a metallic aperture which is tilted by 45 degrees with respect to its trajectory, backward DR that propagates perpendicular to the beam’s trajectory is generated which adds a transverse deflection to the beam as a result of momentum conservation. The deflection is found to be largely dependent on the bunch length and could be easily observed with a downstream BPM. Detailed investigations show that this method has wide applicability, high temporal resolution, and great simplicity.

  13. An Investigation of Presumptive Synergism of Oil Palm Bunch Ash ...

    African Journals Online (AJOL)

    Two kilogram (2 kg) of sandy soil was placed in each of five plastic vessels labeled TA, TB, TC, TD and TE. TA was left in its natural state while the others were each polluted with 6.7% v/w of crude oil. TB was not given any remediation amendment. TC and TD were each amended with 13.3% of oil palm bunch ash and ...

  14. Bunch lengthening with bifurcation in electron storage rings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun-San; Hirata, Kohji [National Lab. for High Energy Physics, Tsukuba, Ibaraki (Japan)

    1996-08-01

    The mapping which shows equilibrium particle distribution in synchrotron phase space for electron storage rings is discussed with respect to some localized constant wake function based on the Gaussian approximation. This mapping shows multi-periodic states as well as double bifurcation in dynamical states of the equilibrium bunch length. When moving around parameter space, the system shows a transition/bifurcation which is not always reversible. These results derived by mapping are confirmed by multiparticle tracking. (author)

  15. Feasibility study of stochastic cooling of bunches in the SPS

    International Nuclear Information System (INIS)

    Boussard, D.; Chattopadhyay, S.; Dome, G.; Linnecar, T.

    1984-01-01

    The average luminosity of the SPS collider could be improved if the slow blow-up of transverse emittances due to beam-beam and intrabeam scattering effects were to be reduced by a transverse cooling system. We examine the parameters of such a system and propose a technological approach which seems better suited to the case of a few bunches circulating in a large machine. (orig./HSI)

  16. Absolute Bunch Length Measurements by Incoherent Radiation Fluctuation Analysis

    International Nuclear Information System (INIS)

    Sannibale, F.; Stupakov, G.V.; Zolotorev, M.S.; Filippetto, D.; Jagerhofer, L.

    2009-01-01

    By analyzing the pulse to pulse intensity fluctuations of the radiation emitted by a charge particle in the incoherent part of the spectrum, it is possible to extract information about the spatial distribution of the beam. At the Advanced Light Source (ALS) of the Lawrence Berkeley National Laboratory, we have developed and successfully tested a simple scheme based on this principle that allows for the absolute measurement of the rms bunch length. A description of the method and the experimental results are presented.

  17. Transient Resistive Wall Wake for Very Short Bunches

    International Nuclear Information System (INIS)

    Stupakov, G.; SLAC

    2005-01-01

    The catch up distance for the resistive wall wake in a round pipe is approximately equal to the square of the pipe radius divided by the bunch length. The standard formulae for this wake are applicable at distances much larger than the catch up distance. In this paper, we calculate the resistive wall wake at distances compared with the catch up distance assuming a constant wall conductivity

  18. Multiple frequency generation by bunched solitons in Josephson tunnel junctions

    DEFF Research Database (Denmark)

    Lomdahl, P. S.; Sørensen, O. H.; Christiansen, Peter Leth

    1981-01-01

    A detailed numerical study of a long Josephson tunnel junction modeled by a perturbed sine-Gordon equation demonstrates the existence of a variety of bunched soliton configurations. Thus, on the third zero-field step of the V-I characteristic, two simultaneous adjacent frequencies are generated...... in a narrow bias current range. The analysis of the soliton modes provides an explanation of recent experimental observations....

  19. Induction Brazing

    DEFF Research Database (Denmark)

    Henningsen, Poul

    , or if the hottest area is located outside the joint interface, a number of defects may appear: the braze metal may flow away from the joint, the flux may burn off, poor binding of the braze metal may appear or the braze metal may be overheated. Joint geometry as well as electro-magnetic properties of the work piece...... presents a combined numerical and experimental method for determination of appropriate/optimiged coil geometry and position in induction brazing tube-to-plate joints of different ratios between tube and plate thickness and different combinations of the materials stainless steel, brass and copper....... The method has proven to give successful results in brazing tube-plate joints of copper-brass, copper-stainless steel, stainless steel-brass, and stainless steel-stainless steel. A new design of an adjustable flux concentrator for induction heating tube-to-plate joints is proposed and tested on a variety...

  20. Characterization of pseudosingle bunch kick-and-cancel operational mode

    Directory of Open Access Journals (Sweden)

    C. Sun

    2015-12-01

    Full Text Available Pseudosingle-bunch kick-and-cancel (PSB-KAC is a new operational mode at the Advanced Light Source of Lawrence Berkeley National Laboratory that provides full timing and repetition rate control for single x-ray pulse users while being fully transparent to other users of synchrotron radiation light. In this operational mode, a single electron bunch is periodically displaced from a main bunch train by a fast kicker magnet with a user-on-demand repetition rate, creating a single x-ray pulse to be matched to a typical laser excitation pulse rate. This operational mode can significantly improve the signal to noise ratio of single x-ray pulse experiments and drastically reduce dose-induced sample damage rate. It greatly expands the capabilities of synchrotron light sources to carry out dynamics and time-of-flight experiments. In this paper, we carry out extensive characterizations of this PSB-KAC mode both numerically and experimentally. This includes the working principle of this mode, resonance conditions and beam stability, experimental setups, and diagnostic tools and measurements.

  1. Characterization of pseudosingle bunch kick-and-cancel operational mode

    Science.gov (United States)

    Sun, C.; Robin, D. S.; Steier, C.; Portmann, G.

    2015-12-01

    Pseudosingle-bunch kick-and-cancel (PSB-KAC) is a new operational mode at the Advanced Light Source of Lawrence Berkeley National Laboratory that provides full timing and repetition rate control for single x-ray pulse users while being fully transparent to other users of synchrotron radiation light. In this operational mode, a single electron bunch is periodically displaced from a main bunch train by a fast kicker magnet with a user-on-demand repetition rate, creating a single x-ray pulse to be matched to a typical laser excitation pulse rate. This operational mode can significantly improve the signal to noise ratio of single x-ray pulse experiments and drastically reduce dose-induced sample damage rate. It greatly expands the capabilities of synchrotron light sources to carry out dynamics and time-of-flight experiments. In this paper, we carry out extensive characterizations of this PSB-KAC mode both numerically and experimentally. This includes the working principle of this mode, resonance conditions and beam stability, experimental setups, and diagnostic tools and measurements.

  2. Emittance control and RF bunch compression in the NSRRC photoinjector

    International Nuclear Information System (INIS)

    Lau, W.K.; Hung, S.B.; Lee, A.P.; Chou, C.S.; Huang, N.Y.

    2011-01-01

    The high-brightness photoinjector being constructed at the National Synchrotron Radiation Research Center is for testing new accelerator and light-source concepts. It is the so-called split photoinjector configuration in which a short solenoid magnet is used for emittance compensation. The UV-drive laser pulses are also shaped to produce uniform cylindrical bunches for further reduction of beam emittance. However, limited by the available power from our microwave power system, the nominal accelerating gradient in the S-band booster linac is set at 18 MV/m. A simulation study with PARMELA shows that the linac operating at this gradient fails to freeze the electron beam emittance at low value. A background solenoid magnetic field is applied for beam emittance control in the linac during acceleration. A satisfactory result that meets our preliminary goal has been achieved with the solenoid magnetic field strength at 0.1 T. RF bunch compression as a means to achieve the required beam brightness for high-gain free-electron laser experiments is also examined. The reduction of bunch length to a few hundred femtoseconds can be obtained.

  3. LHC Report: Boost in bunches brings record luminosity

    CERN Multimedia

    2011-01-01

    Having hit a luminosity of around 8.4x1032 cm-2 s-1 with 768 bunches per beam, the LHC went into a 5-day machine development (MD) program on Wednesday 4 May. Operators are now working on increasing the number of particle bunches in the machine towards a 2011 maximum of around 1380 bunches. The team is already hitting major milestones, recording another record-breaking peak luminosity on Monday 23 May.   Former LHC Project Leader Lyn Evans (to the right) and Laurette Ponce, the engineer-in-charge when the recent luminosity record was achieved. The MD periods improve our understanding of the machine, with the aim of increasing its short- and long-term performance. This one also included tests of the machine’s configurations for special physics runs and a future high luminosity LHC. It was an intense program and overall it went very well, with most measurements carried out successfully. Highlights included: commissioning a dedicated machine setup for TOTEM and ALFA; succe...

  4. Arbitrarily shaped high-coherence electron bunches from cold atoms

    Science.gov (United States)

    McCulloch, A. J.; Sheludko, D. V.; Saliba, S. D.; Bell, S. C.; Junker, M.; Nugent, K. A.; Scholten, R. E.

    2011-10-01

    Ultrafast electron diffractive imaging of nanoscale objects such as biological molecules and defects in solid-state devices provides crucial information on structure and dynamic processes: for example, determination of the form and function of membrane proteins, vital for many key goals in modern biological science, including rational drug design. High brightness and high coherence are required to achieve the necessary spatial and temporal resolution, but have been limited by the thermal nature of conventional electron sources and by divergence due to repulsive interactions between the electrons, known as the Coulomb explosion. It has been shown that, if the electrons are shaped into ellipsoidal bunches with uniform density, the Coulomb explosion can be reversed using conventional optics, to deliver the maximum possible brightness at the target. Here we demonstrate arbitrary and real-time control of the shape of cold electron bunches extracted from laser-cooled atoms. The ability to dynamically shape the electron source itself and to observe this shape in the propagated electron bunch provides a remarkable experimental demonstration of the intrinsically high spatial coherence of a cold-atom electron source, and the potential for alleviation of electron-source brightness limitations due to Coulomb explosion.

  5. Femtosecond electron bunches from an RF-gun

    International Nuclear Information System (INIS)

    Rimjaem, Sakhorn; Farias, Ruy; Thongbai, Chitrlada; Vilaithong, Thiraphat; Wiedemann, Helmut

    2004-01-01

    Sub-picosecond electron pulses become a tool of increasing importance to study dynamics at an atomic level. Such electron pulses can be used directly or be converted into intense coherent far infrared radiation or equally short X-ray pulses. In principle, sub-picosecond electron pulses can be obtained in large, high-energy electron linear accelerator systems by repeatedly applying an energy slew and magnetic compression. Another process is the production of short electron pulses at low energies from an RF-gun with a thermionic cathode together with a bunch compressing α-magnet. In this paper, we present a systematic analysis of capabilities and limits of sub-picosecond electron pulses from such a source. We discuss particular parameter choices as well as the impact of geometric and electric specifications on the 6-dimensional phase space electron distribution. Numerical beam simulations with the computer code PARMELA are performed including effects and limitations due to space charge forces. While the production of femtosecond electron bunches is of primary concern, we also consider the preservation of such short bunches along a beam transport line

  6. Respiratory reovirus 1/L induction of diffuse alveolar damage: pulmonary fibrosis is not modulated by corticosteroids in acute respiratory distress syndrome in mice.

    Science.gov (United States)

    London, Lucille; Majeski, Elizabeth I; Altman-Hamamdzic, Sanja; Enockson, Candace; Paintlia, Manjeet K; Harley, Russell A; London, Steven D

    2002-06-01

    Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by diffuse alveolar damage (DAD) secondary to an intense host inflammatory response of the lung to a pulmonary or extrapulmonary infectious or noninfectious insult. We have previously described a unique animal model in which CBA/J mice infected with reovirus 1/L develop ARDS. This model recapitulates the histopathological changes observed in human ARDS, which consist of the overlapping phases of exudation, including the formation of hyaline membranes, regeneration, and healing via repair with fibrosis. In this report, we show that the development of DAD in the acute phase of the disease and intraalveolar fibrosis in the late phase of the disease was not modulated by treatment with methylprednisolone (MPS). In the presence or absence of MPS, the majority of cells infiltrating the lungs after reovirus 1/L infection were polymorphonuclear leukocytes and macrophages. A number of key proinflammatory and anti-inflammatory cytokines/chemokines that are observed in the BAL fluid of ARDS patients were also found in the lungs of mice after reovirus 1/L infection and were not modulated by MPS. These include interferon-gamma, interleukin-10, and monocyte chemoattractant protein. The histopathology, cytokine/chemokine expression, and response to corticosteroids in reovirus 1/L-induced ARDS are similar to what is observed in human patients, making this a clinically relevant model.

  7. SIMULTANEOUS SPACE VECTOR MODULATION DIRECT TORQUE CONTROL OF TWO INDUCTION MOTORS USED IN ELECTRIC VEHICLES BY A NINE-SWITCH INVERTER

    Directory of Open Access Journals (Sweden)

    A. R. SHAMLOU

    2017-12-01

    Full Text Available In this paper, a novel two output nine switch-inverter is proposed in order to increase the synchronization speed of induction motors used in electric vehicles (EVs while improving the efficiency and controllability of the system. The number of switches in the proposed inverter is reduced by 25% compared to double six-switch inverters which conventionally used in EVs. The main characteristics of the considered inverter can be noted as follows: sinusoidal input and outputs, unity output power factor, and specifically, low construction cost due to active switch number reduction. The classical direct torque control method causes torque ripple and speed fluctuations. Therefore, in order to increase accuracy and dynamics of drive system, the SVM-DTC method is proposed, leading to less torque ripple and constant switching frequency. The obtained torque ripple is 2% which is less than the existing structures In order to illustrate advantages of the proposed approach, performance of the EVs in the standard cycles is evaluated.

  8. Commissioning of an electro-optic electron bunch length monitor at FLASH

    International Nuclear Information System (INIS)

    Breunlin, Jonas

    2011-03-01

    The demands on the electron beam qualities for free-electron lasers (FEL) are challenging in terms of high peak currents. At FLASH, the high-gain FEL in Hamburg, longitudinal bunch compression is performed to achieve the requested high charge densities in short bunches. The precise control of the bunch compression process requires advanced diagnostics on the longitudinal bunch profile. The bunch length monitor presented in this thesis is based on a non-destructive detection using the electro-optic effect. The focus is on a compact and reliable system for permanent bunch diagnostics. The monitor provides single-shot measurements of the longitudinal bunch profiles with lengths of a few picoseconds by spectrally encoding their charge distribution. First measurements for characterization purpose have been performed. It has been shown that the monitor is suitable for monitoring the longitudinal bunch profile behind the first bunch compressor at FLASH. Electron bunch profiles with slopes corresponding to a full width half maximum of about 1.4 ps have been detected. That is the intrinsic resolution limit of the utilized method. (orig.)

  9. Creation and storage of long and flat bunches in the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Damerau, H.

    2005-09-01

    To maximize the luminosity of the Large Hadron Collider (LHC), the collision of particle bunches with a uniform longitudinal particle density is considered for a future upgrade. The benefits of such bunches and their generation by means of special longitudinal beam manipulations are presented in this report. Three possible options are analyzed with respect to their potential luminosity gain at the beam-beam limit: short rectangular bunches held by radio frequency (RF) harmonics using multiples of the nominal RF frequency of 400.8 MHz, long and flat bunches held by multiples of 40.08 MHz, and so-called superbunches, confined by barrier buckets. The comparison of the three different approaches shows that flat bunches, with an intermediate bunch length of the order of several meters, are capable of producing a comparable luminosity to superbunches, while avoiding most of their inherent disadvantages. Possible schemes to create the bunches with uniform line density are studied and a longitudinal manipulation to combine a batch of ordinary bunches into a long and flat bunch is proposed. These RF gymnastics are based on well-proven techniques such as batch compression and bunch pair merging. Their advantages and disadvantages, including optimization with respect to degradation of the longitudinal particle density, are discussed in detail. Special attention is paid to the investigation of collective effects due to the large line charge density and the influence of the beam on the RF installation is also studied. (Orig.)

  10. Intra-bunch-train transverse dynamics in the superconducting accelerators FLASH and European XFEL

    Energy Technology Data Exchange (ETDEWEB)

    Hellert, Thorsten

    2017-11-15

    FLASH and the European XFEL are linear accelerator driven SASE-FELs, operating in a pulsed mode with long bunch-trains. Multi-bunch FEL operation requires longitudinal and transverse stability within the bunch-train. The purpose of this work is to investigate the intra-bunch-train transverse dynamics at FLASH and XFEL. Key relationships of superconducting RF cavity operation, their misalignments and the resulting impact on the intra-bunch-train trajectory variation are described. In this thesis a numerical model is developed and simulations for different accelerating sections at FLASH and XFEL are performed. With the current operational setup significant intra-bunch-train trajectory variation must be considered, hence approaches for their reduction are discussed. The theoretical studies are compared to experimental results at FLASH. The observed trajectory variation during multi-bunch user runs is analyzed and related to causal intra-bunch-train variations of the RF and the following impact on the multi-bunch SASSE performance. Furthermore, HOM-based cavity misalignment measurements are performed and the deduction of misalignments from multi-bunch data is considered.

  11. Measurement of multi-bunch transfer functions using time-domain data and Fourier analysis

    International Nuclear Information System (INIS)

    Hindi, H.; Sapozhnikov, L.; Fox, J.; Prabhakar, S.; Oxoby, G.; Linscott, I.; Drago, A.

    1993-12-01

    Multi-bunch transfer functions are principal ingredients in understanding both the behavior of high-current storage rings as well as control of their instabilities. The measurement of transfer functions on a bunch-by-bunch basis is particularly important in the design of active feedback systems. Traditional methods of network analysis that work well in the single bunch case become difficult to implement for many bunches. We have developed a method for obtaining empirical estimates of the multi-bunch longitudinal transfer functions from the time-domain measurements of the bunches' phase oscillations. This method involves recording the response of the bunch of interest to a white-noise excitation. The transfer function can then be computed as the ratio of the fast Fourier transforms (FFTs) of the response and excitation sequences, averaged over several excitations. The calculation is performed off-line on bunch-phase data and is well-suited to the multi-bunch case. A description of this method and an analysis of its performance is presented with results obtained using the longitudinal quick prototype feedback system developed at SLAC

  12. Intra-bunch-train transverse dynamics in the superconducting accelerators FLASH and European XFEL

    International Nuclear Information System (INIS)

    Hellert, Thorsten

    2017-11-01

    FLASH and the European XFEL are linear accelerator driven SASE-FELs, operating in a pulsed mode with long bunch-trains. Multi-bunch FEL operation requires longitudinal and transverse stability within the bunch-train. The purpose of this work is to investigate the intra-bunch-train transverse dynamics at FLASH and XFEL. Key relationships of superconducting RF cavity operation, their misalignments and the resulting impact on the intra-bunch-train trajectory variation are described. In this thesis a numerical model is developed and simulations for different accelerating sections at FLASH and XFEL are performed. With the current operational setup significant intra-bunch-train trajectory variation must be considered, hence approaches for their reduction are discussed. The theoretical studies are compared to experimental results at FLASH. The observed trajectory variation during multi-bunch user runs is analyzed and related to causal intra-bunch-train variations of the RF and the following impact on the multi-bunch SASSE performance. Furthermore, HOM-based cavity misalignment measurements are performed and the deduction of misalignments from multi-bunch data is considered.

  13. Design of a Multi-Bunch BPM for the Next Linear Collider

    International Nuclear Information System (INIS)

    Young, Andrew

    2003-01-01

    The Next Linear Collider (NLC) design requires precise control of colliding trains of high-intensity (1.4 x 10 10 particles/bunch) and low-emittance beams. High-resolution multi-bunch beam position monitors (BPMs) are required to ensure uniformity across the bunch trains with bunch spacing of 1.4ns. A high bandwidth (∼350 MHz) multi-bunch BPM has been designed based on a custom-made stripline sum and difference hybrid on a Teflon-based material. High bandwidth RF couplers were included to allow injection of a calibration tone. Three prototype BPMs were fabricated at SLAC and tested in the Accelerator Test Facility at KEK and in the PEP-II ring at SLAC. Tone calibration data and single-bunch and multi-bunch beam data were taken with high-speed (5Gsa/s) digitizers. Offline analysis determined the deconvolution of individual bunches in the multi-bunch mode by using the measured single bunch response. The results of these measurements are presented in this paper

  14. Transient response of relativistic electron bunches to wave-number selected perturbations near the micro-bunching instability threshold

    International Nuclear Information System (INIS)

    Roussel, E; Evain, C; Le Parquier, M; Szwaj, C; Bielawski, S; Hosaka, M; Yamamoto, N; Takashima, Y; Shimada, M; Adachi, M; Zen, H; Kimura, S; Katoh, M

    2014-01-01

    Many spatio-temporal systems can undergo instabilities, leading to the spontaneous formation of spatial structures (patterns). However, a range of cases exist for which the pattern itself is not directly visible because of technical or fundamental reasons. This is the case for the spontaneous formation of millimeter-scale patterns appearing inside relativistic electron bunches of accelerators. We demonstrate in this case how the study of responses to sine external perturbations can be used as a ‘probe’ to deduce the characteristic wavenumber of the pattern formation process. Experiments are performed in the UVSOR-II electron storage ring when the electron bunch is subjected to so-called microbunching instability, and the sine perturbations are provided by an external laser. The response is constituted of pulses of coherent synchrotron radiation, whose amplitude depends on the perturbation wavenumber. Experimental results on the dynamics are compared to numerical calculations obtained using a Vlasov–Fokker–Planck model. (paper)

  15. Self-acceleration of relativistic modulated beams

    International Nuclear Information System (INIS)

    Ajzatskij, N.I.

    1989-01-01

    Unlike the case of self-acceleration of continuous beams, the self-acceleration of relativistic modulated beams requires the energy redistribution between the particles not at the period of excited oscillations but rather between the bunches. This may occur only in the case when the electron beam creates a multifrequency equilibrium state in the passive structure. In this case, there is a possibility for some bunches to be captured in the accelerating phase of the field without any external action. The authors have analyzed this possibility both theoretically and experimentally. 12 refs., 2 figs

  16. Main Ring bunch spreaders: Past, 1987/1988 fixed target run, and proposed future

    International Nuclear Information System (INIS)

    Jackson, G.P.

    1989-01-01

    During the last 1987--1988 fixed target running period beam intensity was limited many times by coherent instabilities in both the Main Ring and in the Tevatron. The intensity thresholds for instabilities are generally inversely proportional to the proton bunch length. Since fixed target operations are insensitive to the longitudinal phase space emittance of the beam, bunch spreaders are employed to increase this emittance, and hence the bunch length. As a result, more beam intensity can be delivered to the fixed target experiments. This paper starts with a short history behind the old Main Ring bunch spreader. After discussing the physics of stimulated emittance growth, the design and performance of the 1987--1988 fixed target run Main Ring bunch spreader is discussed. Finally, designs of improved Main Ring and Tevatron bunch spreaders for the next fixed target run are proposed. 23 figs

  17. Simulation of Transverse Multi-Bunch Instabilities of Proton Beams in LHC

    CERN Document Server

    Koschik, Alexander; Zotter, Bruno

    The CERN Large Hadron Collider (LHC) is designed for highest luminosity and therefore requires operation with a large number of bunches and high intensities. Its performance could be limited by the electromagnetic interaction between the charged particle beam and its surroundings which cause collective instabilities. This thesis describes methods of simulating and analyzing multi-bunch instabilities in circular accelerators and storage rings. The simulation models as well as analyzing tools presented here, also facilitate the interpretation of measurements in multi-bunch machines. The 3-dimensional, multi-bunch tracking program MultiTRISIM was developed, based on its single-bunch predecessor TRISIM3D. It allows the exploration of longrange effects in round or flat vacuum chambers for equidistant or uneven filling schemes. Previous computer simulations of collective effects concentrated mainly on instabilities of single or few bunches in electron storage rings. There, the strong radiation damping reduces the r...

  18. Coherent Smith-Purcell radiation as a diagnostic for sub-picosecond electron bunch length

    International Nuclear Information System (INIS)

    Nguyen, D.C.

    1996-01-01

    We suggest a novel technique of measuring sub-picosecond electron bunch length base on coherent Smith-Purcell radiation (SPR) emitted when electrons pass close to the surface of a metal grating. With electron bunch lengths comparable to the grating period, we predict that coherent SPR will be emitted at large angles with respect to direction of beam propagation. As the bunch length shortens, the coherent SPR will be enhanced over the incoherent component that is normally observed at small angles. Furthermore, the angular distribution of the coherent SPR will be shifted toward smaller angles as the bunch length becomes much smaller than the grating period. By measuring the angular distribution of the coherent SPR, one can determine the bunch length of sub-picosecond electron pulses. This new technique is easy to implement and appears capable of measuring femtosecond electron bunch lengths

  19. LHC MD 652: Coupled-Bunch Instability with Smaller Emittance (all HOMs)

    CERN Document Server

    AUTHOR|(CDS)2081238; Timko, Helga; CERN. Geneva. ATS Department

    2017-01-01

    The aim of the MD was to measure the coupled-bunch stability from all HOM impedances, with a reduced longitudinal emittance in order to explore the HL-LHC conditions. The acceleration ramp was performed with the nominal beams of 2016, but a reduced target bunch length and RF voltage. With this reduced emittance, the beam remained close but above the single-bunch stability threshold. No coupled-bunch oscillations were observed, so we can conclude that the stability threshold for coupled-bunch instability is not lower than the single-bunch threshold. An interesting observation in the MD was the long-lasting injection oscillations, whose traces can still be seen at arrival to flat top; in agreement with observations in earlier MDs. The measurements took place between 28th October 20:00 and 29th October 05:10.

  20. Modulation of the BRCA1 Protein and Induction of Apoptosis in Triple Negative Breast Cancer Cell Lines by the Polyphenolic Compound Curcumin

    Directory of Open Access Journals (Sweden)

    Danica L. Rowe

    2009-09-01

    Full Text Available In the current study, we sought to examine the effects of curcumin in a specific type of breast cancer called triple negative breast cancer. These cancers lack expression of the estrogen and progesterone receptors and do not over-express HER2. Current treatment for triple negative breast cancers is limited to cytotoxic chemotherapy, and upon relapse, there are not any therapies currently available. We demonstrate here that the bioactive food compound curcumin induces DNA damage in triple negative breast cancer cells in association with phosphorylation, increased expression, and cytoplasmic retention of the BRCA1 protein. In addition, curcumin promotes apoptosis and prevents anchorage-independent growth and migration of triple negative breast cancer cells. Apoptosis and BRCA1 modulation were not observed in non-transformed mammary epithelial cells, suggesting curcumin may have limited non-specific toxicity. This study suggests that curcumin and potentially curcumin analogues should be tested further in the context of triple negative breast cancer. These results are novel, having never been previously reported, and suggest that curcumin could provide a novel, non-toxic therapy, which could lead to improved survival for patients with triple negative breast cancer. Curcumin should be studied further in this subset of breast cancer patients, for whom treatment options are severely limited.

  1. Anticancer Applications of Nanostructured Silica-Based Materials Functionalized with Titanocene Derivatives: Induction of Cell Death Mechanism through TNFR1 Modulation

    Directory of Open Access Journals (Sweden)

    Santiago Gómez-Ruiz

    2018-01-01

    Full Text Available A series of cytotoxic titanocene derivatives have been immobilized onto nanostructured silica-based materials using two different synthetic routes, namely, (i a simple grafting protocol via protonolysis of the Ti–Cl bond; and (ii a tethering method by elimination of ethanol using triethoxysilyl moieties of thiolato ligands attached to titanium. The resulting nanostructured systems have been characterized by different techniques such as XRD, XRF, DR-UV, BET, SEM, and TEM, observing the incorporation of the titanocene derivatives onto the nanostructured silica and slight changes in the textural features of the materials after functionalization with the metallodrugs. A complete biological study has been carried out using the synthesized materials exhibiting moderate cytotoxicity in vitro against three human hepatic carcinoma (HepG2, SK-Hep-1, Hep3B and three human colon carcinomas (DLD-1, HT-29, COLO320 and very low cytotoxicity against normal cell lines. In addition, the cells’ metabolic activity was modified by a 24-h exposure in a dose-dependent manner. Despite not having a significant effect on TNFα or the proinflammatory interleukin 1α secretion, the materials strongly modulated tumor necrosis factor (TNF signaling, even at sub-cytotoxic concentrations. This is achieved mainly by upregulation of the TNFR1 receptor production, something which has not previously been observed for these systems.

  2. Induction of Osmoregulation and Modulation of Salt Stress in Acacia gerrardii Benth. by Arbuscular Mycorrhizal Fungi and Bacillus subtilis (BERA 71

    Directory of Open Access Journals (Sweden)

    Abeer Hashem

    2016-01-01

    Full Text Available The role of soil microbiota in plant stress management, though speculated a lot, is still far from being completely understood. We conducted a greenhouse experiment to examine synergistic impact of plant growth promoting rhizobacterium, Bacillus subtilis (BERA 71, and arbuscular mycorrhizal fungi (AMF (Claroideoglomus etunicatum; Rhizophagus intraradices; and Funneliformis mosseae to induce acquired systemic resistance in Talh tree (Acacia gerrardii Benth. against adverse impact of salt stress. Compared to the control, the BERA 71 treatment significantly enhanced root colonization intensity by AMF, in both presence and absence of salt. We also found positive synergistic interaction between B. subtilis and AMF vis-a-vis improvement in the nutritional value in terms of increase in total lipids, phenols, and fiber content. The AMF and BERA 71 inoculated plants showed increased content of osmoprotectants such as glycine, betaine, and proline, though lipid peroxidation was reduced probably as a mechanism of salt tolerance. Furthermore, the application of bioinoculants to Talh tree turned out to be potentially beneficial in ameliorating the deleterious impact of salinity on plant metabolism, probably by modulating the osmoregulatory system (glycine betaine, proline, and phenols and antioxidant enzymes system (SOD, CAT, POD, GR, APX, DHAR, MDAHR, and GSNOR.

  3. Stability of longitudinal oscillations of a bunch propagating through an evacuated chamber with reactive impedance

    International Nuclear Information System (INIS)

    Besnier, G.

    1979-01-01

    The longitudinal space-charge force is assumed to vary like the derivative of the longitudinal beam density. Solutions of the linearized Vlasov equation are then given as an expansion of normal modes for the longitudinal phase-space density of a bunched beam. For a given bunch intensity, the method allows calculation of the required synchrotron frequency spread inside a parabolic bunch, in order to stabilize the beam against coherent oscillations by Landau-damping. (Auth.)

  4. Methods For Electron Bunch Measurement With Resolution Of The Order Of 1 Fs And 1 Nm

    CERN Document Server

    Tron, A M

    2004-01-01

    Methods for bunch length and shape monitoring with femtosecond resolution by means of time converting photochronography of the bunch radiation in the range of visible light using photoelectron camera of new principle of its operation, and for monitoring the transverse bunch size, based on new beam cross section wire scanner technique where the depth of electron escapement being not more than 1 nm is used, are described. Main limitation, caused by space charge effect, is considered.

  5. Spatial configuration of a plasma bunch formed under gyromagnetic resonance in a magnetic mirror trap

    Energy Technology Data Exchange (ETDEWEB)

    Andreev, V. V.; Novitskii, A. A.; Umnov, A. M.; Chuprov, D. V., E-mail: chu-d@mail.ru [Peoples’ Friendship University of Russia (Russian Federation)

    2016-06-15

    The spatial configuration of a relativistic plasma bunch generated under the gyromagnetic autoresonance and confined in a magnetic mirror trap has been studied experimentally and numerically. The characteristics of bremsstrahlung generated by the plasma bunch from the gas and chamber walls were investigated using X-ray spectroscopy and radiometry, which made it possible to determine the localization of the bunch and analyze the dynamics of its confinement.

  6. On the acceleration of charged particles by strong longitudinal plasma wake fields excited by electron bunches

    International Nuclear Information System (INIS)

    Amatuni, A.Ts.; Elbakyan, S.S.; Sekhpossyan, E.V.

    1985-01-01

    The possibility of the use of longitudinal field excited in a plasma by electron bunches to accelerate charged particles is investigated. It is shown that the highets value of accelerating fields proportional to the square root of factor of electrons in the bunch is achieved in the case when bunch particle density approaches a limit equal to the half of the the plasma electron equilibrium density

  7. Investigation of advanced electron bunch generation and diagnostics in the BOND laboratory at DESY

    OpenAIRE

    Kononenko, Olena; Bohlen, Simon; Gruse, Jan-Niclas; Karstensen, Sven; Libov, Vladyslav; Ludwig, Kai; Martinez de la Ossa, Alberto; Marutzky, Frank; Niroula, Avinash; Osterhoff, Jens; Quast, Martin; Schaper, Lucas; Dale, John; Schwinkendorf, Jan-Patrick; Streeter, Matthew

    2016-01-01

    Laser driven plasma wakefield accelerators have been explored as a potential compact, reproducible source of relativistic electron bunches, utilising an electric field of many GV/m. Control over injection of electrons into the wakefield is of crucial importance in producing stable, mono-energetic electron bunches. Density tailoring of the target, to control the acceleration process, can also be used to improve the quality of the bunch. By using gas jets to provide tailored targets it is poss...

  8. Application of constrained deconvolution technique for reconstruction of electron bunch profile with strongly non-Gaussian shape

    Science.gov (United States)

    Geloni, G.; Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

    2004-08-01

    An effective and practical technique based on the detection of the coherent synchrotron radiation (CSR) spectrum can be used to characterize the profile function of ultra-short bunches. The CSR spectrum measurement has an important limitation: no spectral phase information is available, and the complete profile function cannot be obtained in general. In this paper we propose to use constrained deconvolution method for bunch profile reconstruction based on a priori-known information about formation of the electron bunch. Application of the method is illustrated with practically important example of a bunch formed in a single bunch-compressor. Downstream of the bunch compressor the bunch charge distribution is strongly non-Gaussian with a narrow leading peak and a long tail. The longitudinal bunch distribution is derived by measuring the bunch tail constant with a streak camera and by using a priory available information about profile function.

  9. Application of constrained deconvolution technique for reconstruction of electron bunch profile with strongly non-Gaussian shape

    International Nuclear Information System (INIS)

    Geloni, G.; Saldin, E.L.; Schneidmiller, E.A.; Yurkov, M.V.

    2004-01-01

    An effective and practical technique based on the detection of the coherent synchrotron radiation (CSR) spectrum can be used to characterize the profile function of ultra-short bunches. The CSR spectrum measurement has an important limitation: no spectral phase information is available, and the complete profile function cannot be obtained in general. In this paper we propose to use constrained deconvolution method for bunch profile reconstruction based on a priori-known information about formation of the electron bunch. Application of the method is illustrated with practically important example of a bunch formed in a single bunch-compressor. Downstream of the bunch compressor the bunch charge distribution is strongly non-Gaussian with a narrow leading peak and a long tail. The longitudinal bunch distribution is derived by measuring the bunch tail constant with a streak camera and by using a priory available information about profile function

  10. MBE-4: an induction linac experiment for heavy ion fusion

    International Nuclear Information System (INIS)

    Fessenden, T.J.; Avery, R.T.; Brodzik, D.A.

    1986-06-01

    The multiple-beam induction linac approach to a heavy ion fusion driver features continuous current amplification along the accelerator and a minimum of transverse beam manipulation from source to pellet. Current amplification and bunch length control require careful shaping of the accelerating voltages. This driver approach exploits developments in electron induction linac technology that have occurred within the last 15 years at LBL, LLNL and NBS. MBE-4 is a four beam induction linac that models much of the accelerator physics of the electrostatically focused section of a considerably longer induction accelerator. Four parallel Cs + beams are electrostatically focussed and will be accelerated from 200 keV to approximately one MeV when the experiment is complete in the spring of 1987. The current in each of the four beams will increase from 10 to 40 mA due to both increase in beam speed and shortening of the bunch length. Results of experiments with the injector and first eight accelerating gaps are presented

  11. On the preservation of single- and multi-bunch emittance in linear accelerators

    International Nuclear Information System (INIS)

    Drevlak, M.

    1995-11-01

    This document is concentrated on the investigation of the dynamics of a particle beam in a linear accelerator. We numerically simulate a number of effects and evaluate the severity of their impact on the beam. Furthermore, we examine the applicability of several correction techniques aiming at the suppression or correction of the effects diluting the beam emittance. First, there is the issue of single-bunch dynamics : we see that wake field effects and dispersive errors can cause a significant emittance growth. Secondly, long range dipole wakes and dispersive effects arising from the energy spread between different bunches will cause relative offsets between the individual bunches and likewise result in emittance growth. Finally, we observe interactions between the single-bunch and multi-bunch dynamics in a bunch train, which further aggravate these effects. The corrective measures against emittance growth are first tested with respect to individual effects relating to issues of single- or multi-bunch dynamics. Later, these different correction techniques are joined to one machine tuning procedure that will be applied in order to achieve good emittance preservation for operation of the accelerator with a full beam consisting of the full number of bunches. The performance of this procedure is tested in simulations of the combined single- and multi-bunch dynamics. Finally, tolerances on the machine alignment as well as machine and beam parameters are established. (orig.)

  12. Transverse multibunch modes for non-rigid bunches, including mode coupling

    Energy Technology Data Exchange (ETDEWEB)

    Berg, J S; Ruth, R D [Stanford Linear Accelerator Center, Menlo Park, CA (United States)

    1996-08-01

    A method for computing transverse multibunch growth rates and frequency shifts in rings, which has been described previously, is applied to the PEP-II B factory. The method allows multibunch modes with different internal-bunch oscillation modes to couple to one another, similar to single-bunch mode coupling. Including coupling between the multibunch modes gives effects similar to those seen in single-bunch mode coupling. These effects occur at currents that are lower than the single-bunch mode coupling threshold. (author)

  13. Timing system for multi-bunch/multi-train operation at ATF

    International Nuclear Information System (INIS)

    Naito, T.; Hayano, H.; Urakawa, J.; Imai, T.

    2000-01-01

    A timing system has been constructed for multi-bunch/multi-train operation at KEK-ATF. The linac accelerates 20 bunches of multi-bunch with 2.8 ns spacing. The Damping Ring stores up to 5 trains of multi-bunch. The timing system is required to provide flexible operation mode and bucket selection. A personal computer is used for manipulating the timing. The performance of kicker magnets at the injection/extruction is key issue for multi-train operation. The hardware and the test results are presented. (author)

  14. Measurement of the longitudinal wakefield and the bunch shape in the SLAC linac

    International Nuclear Information System (INIS)

    Bane, K.L.F.; Decker, F.J.; Seeman, J.T.; Zimmermann, F.

    1997-05-01

    The authors report on measurements of the bunch energy spectrum at the end of the SLAC linac. Using the spectra obtained for two different linac rf phases they obtain both the bunch induced voltage and the longitudinal distribution of the bunch. The measurement results are compared with theoretical predictions. In particular, the induced voltage is in good agreement with that obtained using the calculated wake function for the SLAC linac. This measurement technique may be useful for monitoring changes of the linac bunch shape in the SLC

  15. Beam beam tune shifts for 36 bunch operation in the Tevatron

    International Nuclear Information System (INIS)

    Bagley, P.

    1996-10-01

    We are preparing to upgrade the Tevatron Collider from 6 to 36 bunch operation. The 36 bunches are in 3 ''trains'' of 12 bunches. The spacing between bunches within a train is 21 RF buckets (53.106 MHz) and 139 empty buckets separate the trains. Because the 36 bunches are not evenly spaced around the machine, the different bunches within a train pass the opposing bunches at different points in the ring and so feel different beam beam effects. Through most of the machine the beams have helical separation, so these are mainly long range beam beam effects. As a first, very simple step, we've looked at the differences in the tunes of the different anti-proton (anti p) bunches. During the 36 bunch studies in Fall 1995, we used a new tune measurement system to measure these in several different machine conditions. We compare these measurements to calculations of the tunes for a anti p with zero transverse and longitudinal oscillation amplitudes. We discuss experimental problems, and the assumptions, approximations, and effects included in the calculations. Our main intent is to gain confidence that we can accurately model beam beam effects in the Tevatron

  16. Transverse modes of a bunched beam with space charge dominated impedance

    Directory of Open Access Journals (Sweden)

    V. Balbekov

    2009-12-01

    Full Text Available Transverse coherent oscillations of a bunched beam in a ring accelerator are considered with space charge dominated impedance, taking into account linear synchrotron oscillations. A general equation of the bunch eigenmodes is derived, its exact analytical solution is presented for boxcar bunch, and numerical solutions are found for several realistic models. Both low and high synchrotron frequency approximations are considered and compared, fields of their applicability are determined, and some estimations are developed in the intermediate region. It is shown that most of the bunch eigenmodes are stabilized by Landau damping due to the space charge produced tune spread.

  17. Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities

    International Nuclear Information System (INIS)

    Borkham-Kamphorst, Erawan; Alexi, Pascal; Tihaa, Lidia; Haas, Ute; Weiskirchen, Ralf

    2015-01-01

    Platelet-derived growth factor-D (PDGF-D) is a more recent recognized growth factor involved in the regulation of several cellular processes, including cell proliferation, transformation, invasion, and angiogenesis by binding to and activating its cognate receptor PDGFR-β. After bile duct ligation or in the carbon tetrachloride-induced hepatic fibrosis model , PDGF-D showed upregulation comparable to PDGF-B. Moreover, adenoviral PDGF-D gene transfer induced hepatic stellate cell proliferation and liver fibrosis. We here investigated the molecular mechanism of PDGF-D involvement in liver fibrogenesis. Therefore, the GRX mouse cell line was stimulated with PDGF-D and evaluated for fibrotic markers and PDGF-D signaling pathways in comparison to the other PDGF isoforms. We found that PDGF-D failed to enhance Col I and α-smooth muscle actin (α-SMA) production but has capacity to upregulate expression of the tissue inhibitor of metalloprotease 1 (TIMP-1) resulting in attenuation of MMP-2 and MMP-9 gelatinase activity as indicated by gelatinase zymography. This phenomenon was restored through application of a PDGF-D neutralizing antibody. Unexpectedly, PDGF-D incubation decreased both PDGFR-α and -β in mRNA and protein levels, and PDGF-D phosphorylated typrosines specific for PDGFR-α and -β. We conclude that PDGF-D intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP system and that PDGF-D signaling is mediated through both PDGF-α and -β receptors. - Highlights: • PDGF-D signals through PDGF receptor type α and β. • PDGF-D modulates extracellular matrix homeostasis and remodeling. • Like PDGF-B, PDGF-D triggers phosphorylation of PLC-γ, Akt/PKB, JNK, ERK1/2, and p38. • PDGF-D induces TIMP-1 expression through ERK and p38 MAPK. • PDGF-D attenuates MMP-2 and MMP-9 gelatinase activities

  18. Thyroid Cancer Induction: Nitrates as Independent Risk Factors or Risk Modulators after Radiation Exposure, with a Focus on the Chernobyl Accident.

    Science.gov (United States)

    Drozd, Valentina M; Branovan, Igor; Shiglik, Nikolay; Biko, Johannes; Reiners, Christoph

    2018-03-01

    In recent decades, differentiated thyroid cancer (DTC) incidence has been increasing worldwide. The important contributions to this phenomenon of "overdiagnosis" driven by wider use of improved ultrasound systems are amply documented, notwithstanding the "real" carcinogenic effects of ionizing radiation, e.g., from the Chernobyl accident or health care interventions. Less well understood is the role of nitrates - as environmental pollutants, in diet, and in medication - in thyroid carcinogenesis. Increasing exposure to nitrates is associated with rising incidence of esophageal, stomach, bladder, and colon cancers. Recent data suggest that in agricultural areas with higher mean nitrate levels in groundwater, DTC risk is also elevated. Our work in Belarus after Chernobyl has shown that children in districts with high nitrate concentrations in drinking water had significantly higher thyroid cancer incidence after irradiation than did their counterparts in areas with lower nitrate concentrations. Notwithstanding thyroid shielding, increasing use of computed tomography and dental X-rays heightens radiation exposure of the salivary glands in the general population, especially in children and adolescents. When nitrate intake is increased, salivary gland irradiation may potentially result in carcinogenic elevations in plasma nitric oxide concentrations. In conclusion, excess nitrate intake seems to be an independent risk factor for DTC. Additionally, we hypothesize from our data that high nitrate levels modulate the carcinogenic effect of radiation on the thyroid. Cohort studies, case-control studies, or both, are needed to quantify the effects of nitrates on DTC risk in the presence or absence of radiation exposure, e.g., that associated with diagnostic or therapeutic health care interventions.

  19. Much Ado about Microbunching: Coherent Bunching in High Brightness Electron Beams

    Energy Technology Data Exchange (ETDEWEB)

    Ratner, Daniel [Stanford Univ., CA (United States)

    2011-05-01

    The push to provide ever brighter coherent radiation sources has led to the creation of correspondingly bright electron beams. With billions of electrons packed into normalized emittances (phase space) below one micron, collective effects may dominate both the preservation and use of such ultra-bright beams. An important class of collective effects is due to density modulations within the bunch, or microbunching. Microbunching may be deleterious, as in the case of the Microbunching Instability (MBI), or it may drive radiation sources of unprecedented intensity, as in the case of Free Electron Lasers (FELs). In this work we begin by describing models of microbunching due to inherent beam shot noise, which sparks both the MBI as well as SLAC's Linac Coherent Light Source, the world's first hard X-ray laser. We first use this model to propose a mechanism for reducing the inherent beam shot noise as well as for predicting MBI effects. We then describe experimental measurements of the resulting microbunching at LCLS, including optical radiation from the MBI, as well as the first gain length and harmonic measurements from a hard X-ray FEL. In the final chapters, we describe schemes that use external laser modulations to microbunch light sources of the future. In these sections we describe coherent light source schemes for both both linacs and storage rings.

  20. Mechanical Properties of Oil Palm Empty Fruit Bunch Fiber

    Science.gov (United States)

    Gunawan, Fergyanto E.; Homma, Hiroomi; Brodjonegoro, Satryo S.; Hudin, Afzer Bin Baseri; Zainuddin, Aryanti Binti

    In tropical countries such as Indonesia and Malaysia, the empty fruit bunches are wastes of the oil palm industry. The wastes are abundantly available and has reached a level that severely threats the environment. Therefore, it is a great need to find useful applications of those waste materials; but firstly, the mechanical properties of the EFB fiber should be quantified. In this work, a small tensile test machine is manufactured, and the tensile test is performed on the EFB fibers. The results show that the strength of the EFB fiber is strongly affected by the fiber diameter; however, the fiber strength is relatively low in comparison to other natural fibers.

  1. Chromatic correction in the SLC bunch length compressors

    International Nuclear Information System (INIS)

    Adolphsen, C.E.; Emma, P.J.; Fieguth, T.H.; Spence, W.L.

    1991-06-01

    The SLC Ring to Linac (RTL) transport lines employ intense bending and strong transverse focusing to produce the momentum compaction needed for bunch length compression prior to S-band acceleration. In the presence of the large rf induced energy spread needed for compression the consequent chromatic effects -- viz. the variation with energy of residual output dispersion and of the RTL transfer matrix, threaten to destroy the small emittances produced by the damping rings. We report on the tuning methods that have been developed and used to implement the sextupole based chromatic correction scheme. 6 refs., 4 figs

  2. Optimized Bunch Compression System for the European XFEL

    CERN Document Server

    Limberg, Torsten; Brinkmann, Reinhard; Decking, Winfried; Dohlus, Martin; Flöettmann, Klaus; Kim, Yujong; Schneidmiller, Evgeny

    2005-01-01

    The European XFEL bunch compressor system has been optimized for greater flexibility in parameter space. Operation beyond the XFEL design parameters is discussed in two directions: achieving the uppermost number of photons in a single pulse on one hand and reaching the necessary peak current for lasing with a pulse as short as possible on the other. Results of start-to-end calculations including 3D-CSR effects, space charge forces and the impact on wake fields demonstrate the potential of the XFEL for further improvement or, respectively, its safety margin for operation at design values.

  3. Self-focusing of electron bunches in a nonlinear plasma

    International Nuclear Information System (INIS)

    Krasovitskii, V.B.; Osmolovsky, S.I.

    1994-01-01

    The phenomena of self-focusing of previously bunched electron beam in hot nonlinear plasma with the frequency which less than the plasma one is studied. It is established that influence of the Miller's force nonlinearity of the plasma don't leads to self-focusing breaking. However in the case of a dense beam, the appearance strong resonant electric field is followed by the change of the sign of the plasma dielectric constant to positive at the beam axis. But the dielectric constant remain negative at the outer of the beam

  4. Overview of coupled bunch active damper systems at FNAL

    International Nuclear Information System (INIS)

    Steimel, J.; Crisp, J.; Ma, Hengjie; Marriner, J.; McGinnis, D.

    1996-05-01

    Beam intensities in all of the accelerators at Fermilab will increase significantly when the Main Injector becomes operational and will cause unstable oscillations in transverse position and energy. Places where the coupled bunch oscillations could dilute emittances include the Booster, Main Injector, and Tevatron. This paper provides an overview of the active feedback system upgrades which will be used to counteract the problem. It will explain the similarities between all the systems and will also explain design differences between longitudinal and transverse systems, fast sweeping systems, and systems for partially filled machines. Results from operational systems will also be shown. 7 refs., 4 figs., 1 tab

  5. A BUNCH TO BUCKET PHASE DETECTOR USING DIGITAL RECEIVER TECHNOLOGY

    International Nuclear Information System (INIS)

    DELONG, J.; BRENNAN, J.M.; HAYES, T.; LE, T.N.; SMITH, K.

    2003-01-01

    Transferring high-speed digital signals to a Digital Signal Processor is limited by the IO bandwidth of the DSP. A digital receiver circuit is used to translate high frequency W signals to base-band. The translated output frequency is close to DC and the data rate can be reduced, by decimation, before transfer to the DSP. By translating both the longitudinal beam (bunch) and RF cavity pick-ups (bucket) to DC, a DSP can be used to measure their relative phase angle. The result can be used as an error signal in a beam control servo loop and any phase differences can be compensated

  6. Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities

    Energy Technology Data Exchange (ETDEWEB)

    Borkham-Kamphorst, Erawan, E-mail: ekamphorst@ukaachen.de; Alexi, Pascal; Tihaa, Lidia; Haas, Ute; Weiskirchen, Ralf, E-mail: rweiskirchen@ukaachen.de

    2015-02-13

    Platelet-derived growth factor-D (PDGF-D) is a more recent recognized growth factor involved in the regulation of several cellular processes, including cell proliferation, transformation, invasion, and angiogenesis by binding to and activating its cognate receptor PDGFR-β. After bile duct ligation or in the carbon tetrachloride-induced hepatic fibrosis model{sub ,} PDGF-D showed upregulation comparable to PDGF-B. Moreover, adenoviral PDGF-D gene transfer induced hepatic stellate cell proliferation and liver fibrosis. We here investigated the molecular mechanism of PDGF-D involvement in liver fibrogenesis. Therefore, the GRX mouse cell line was stimulated with PDGF-D and evaluated for fibrotic markers and PDGF-D signaling pathways in comparison to the other PDGF isoforms. We found that PDGF-D failed to enhance Col I and α-smooth muscle actin (α-SMA) production but has capacity to upregulate expression of the tissue inhibitor of metalloprotease 1 (TIMP-1) resulting in attenuation of MMP-2 and MMP-9 gelatinase activity as indicated by gelatinase zymography. This phenomenon was restored through application of a PDGF-D neutralizing antibody. Unexpectedly, PDGF-D incubation decreased both PDGFR-α and -β in mRNA and protein levels, and PDGF-D phosphorylated typrosines specific for PDGFR-α and -β. We conclude that PDGF-D intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP system and that PDGF-D signaling is mediated through both PDGF-α and -β receptors. - Highlights: • PDGF-D signals through PDGF receptor type α and β. • PDGF-D modulates extracellular matrix homeostasis and remodeling. • Like PDGF-B, PDGF-D triggers phosphorylation of PLC-γ, Akt/PKB, JNK, ERK1/2, and p38. • PDGF-D induces TIMP-1 expression through ERK and p38 MAPK. • PDGF-D attenuates MMP-2 and MMP-9 gelatinase activities.

  7. Accelerator research on MBE-4, an experimental multi-beam induction linac

    International Nuclear Information System (INIS)

    Meuth, H.; Fessenden, T.J.; Keefe, D.; Warwick, A.I.

    1988-06-01

    The multiple beam accelerator MBE-4 is a device for research toward a heavy ion driver for inertial confinement fusion, based on the induction linac concept. Its main goal is proof of the principle of current amplification by acceleration and controlled self-similar beam pulse compression. Into the 16-m long device four beams, each with an initial current of 10 mA are injected from a Marx-driven diode at 200 keV. The current amplification is up to nine-fold, with a final beam energy of about 800 keV in the middle of the bunch. Now that all the apparatus' accelerator sections have been completed, installed and aligned, and its unaccelerated transport properties have been studied, our experimental research has reached the crucial phase of implementing appropriate accelerator schedules that approximate self-similar current-pulse compression. These schedules are established through a close interplay of computations using a one-dimensional simulation code and a manual empirical tuning procedure. In a first approach, with a rather vigorous schedule that uses most of the accelerator modules to their voltage limits, we have determined the limits of our capability for controlled pulse compression, mainly due to waveform shaping of the driving pulse-forming networks. We shall report on these results. In the future, we will also aim for gentler schedules that would model more closely an inertial confinement fusion scenario. 8 refs., 11 figs., 1 tab

  8. Logic and control module for the Fermilab booster beam damper

    International Nuclear Information System (INIS)

    Sandberg, B.R.

    1977-01-01

    A logic and control module is included in the electronic system of the booster superdamper. This module produces a 9-bit digital word that controls the delay of beam bunch position information in the Fermilab booster synchrotron so that it arrives at the damping electrodes at the same time as the bunch of beam to be corrected. This delay word generator also has an output feature that only allows delay time decreases as the booster synchrotron frequency program increases monotonically. Such a feature guards against low-index incidental FM from affecting the delay computations

  9. Performance Analysis of a Four-Switch Three-Phase Grid-Side Converter with Modulation Simplification in a Doubly-Fed Induction Generator-Based Wind Turbine (DFIG-WT with Different External Disturbances

    Directory of Open Access Journals (Sweden)

    Kai Ni

    2017-05-01

    Full Text Available This paper investigates the performance of a fault-tolerant four-switch three-phase (FSTP grid-side converter (GSC in a doubly-fed induction generator-based wind turbine (DFIG-WT. The space vector pulse width modulation (SVPWM technique is simplified and unified duty ratios are used for controlling the FSTP GSC. Steady DC-bus voltage, sinusoidal three-phase grid currents and unity power factor are obtained. In addition, the balance of capacitor voltages is accomplished based on the analysis of current flows at the midpoint of DC bus in different operational modes. Besides, external disturbances such as fluctuating wind speed and grid voltage sag are considered to test its fault-tolerant ability. Furthermore, the effects of fluctuating wind speed on the performance of DFIG-WT system are explained according to an approximate expression of the turbine torque. The performance of the proposed FSTP GSC is simulated in Matlab/Simulink 2016a based on a detailed 1.5 MW DFIG-WT Simulink model. Experiments are carried out on a 2 kW platform by using a discrete signal processor (DSP TMS320F28335 controller to validate the reliability of DFIG-WT for the cases with step change of the stator active power and grid voltage sag, respectively.

  10. Effect of interleukin-2 on cell proliferation, sister-chromatid exchange induction, and nuclear stress protein phosphorylation in PHA-stimulated Fischer 344 rat spleen lymphocytes: Modulation by 2-mercaptoethanol

    Energy Technology Data Exchange (ETDEWEB)

    Morris, S.M.; Aidoo, A.; Domon, O.E.; McGarrity, L.J.; Kodell, R.L.; Schol, H.M.; Hinson, W.G.; Pipkin, J.L.; Casciano, D.A. (National Center for Toxicological Research, Jefferson, AR (USA))

    1990-01-01

    The effect of interleukin-2 (IL-2) on cell proliferation, sister-chromatid exchange (SCE) frequency, and the phosphorylation of nuclear stress proteins was evaluated in phytohemagglutinin (PHA)-stimulated spleen lymphocytes isolated from Fischer 344 rats. In addition, the ability of 2-mercaptoethanol (2-ME) to modulate the induction of these biological responses was characterized. Cell proliferation, as measured by the mitotic index, increased significantly. The average generation time (AGT) did not respond to IL-2 in a concentration-dependent manner and decreased significantly. The number of SCE increased significantly from control frequencies, to frequencies of 18.5 to 21.5 SCE per cell as the concentration of IL-2 in the culture medium increased to 50 half-maximal units per ml. A reduction in SCE frequency was observed when cells were cultured with 20 {mu}M 2-ME and IL-2 compared to IL-2 alone. Three nuclear proteins, with relative molecular masses of approximately 13,000-18,000, 20,000, and 80,000, were phosphorylated in IL-2-exposed G{sub 1}-phase nuclei. Elicitation of these nuclear proteins in IL-2-exposed cells was not affected by exposure to 2-ME.

  11. Measuring the electron beam energy in a magnetic bunch compressor

    International Nuclear Information System (INIS)

    Hacker, Kirsten

    2010-09-01

    Within this thesis, work was carried out in and around the first bunch compressor chicane of the FLASH (Free-electron LASer in Hamburg) linear accelerator in which two distinct systems were developed for the measurement of an electron beams' position with sub-5 μm precision over a 10 cm range. One of these two systems utilized RF techniques to measure the difference between the arrival-times of two broadband electrical pulses generated by the passage of the electron beam adjacent to a pickup antenna. The other system measured the arrival-times of the pulses from the pickup with an optical technique dependent on the delivery of laser pulses which are synchronized to the RF reference of the machine. The relative advantages and disadvantages of these two techniques are explored and compared to other available approaches to measure the same beam property, including a time-of-flight measurement with two beam arrival-time monitors and a synchrotron light monitor with two photomultiplier tubes. The electron beam position measurement is required as part of a measurement of the electron beam energy and could be used in an intra-bunch-train beam-based feedback system that would stabilize the amplitude of the accelerating field. By stabilizing the accelerating field amplitude, the arrival-time of the electron beam can be made more stable. By stabilizing the electron beam arrival-time relative to a stable reference, diagnostic, seeding, and beam-manipulation lasers can be synchronized to the beam. (orig.)

  12. Coherent synchrotron radiation and bunch stability in a compactstorage ring

    Energy Technology Data Exchange (ETDEWEB)

    Venturini, Marco; Warnock, Robert; Ruth, Ronald; Ellison, James A.

    2004-04-09

    We examine the effect of the collective force due to coherent synchrotron radiation (CSR) in an electron storage ring with small bending radius. In a computation based on time-domain integration of the nonlinear Vlasov equation, we find the threshold current for a longitudinal microwave instability induced by CSR alone. The model accounts for suppression of radiation at long wave lengths due to shielding by the vacuum chamber. In a calculation just above threshold, small ripples in the charge distribution build up over a fraction of a synchrotron period, but then die out to yield a relatively smooth but altered distribution with eventual oscillations in bunch length. The instability evolves from small noise on an initial smooth bunch of r.m.s.length much greater than the shielding cutoff. The paper includes a derivation and extensive analysis of the complete impedance function Z for synchrotron radiation with parallel plate shielding. We find corrections to the lowest approximation to the coherent force which involve ''off-diagonal'' values of Z, that is, fields with phase velocity not equal to the particle velocity.

  13. A combined source of electron bunches and microwave power

    International Nuclear Information System (INIS)

    Xie, J.L.; Wang, F.Y.; Yang, X.P.; Shen, B.; Gu, W.; Zhang, L.W.

    2003-01-01

    In this article, the possibility of using a high power klystron amplifier simultaneously as a microwave power source as usual and an electron bunches source by extracting the spent beam with a magnet and also as an oscillator by feedback is investigated. The purpose of this study is to demonstrate the feasibility of constructing a very compact electron linear accelerator or for other applications of electron bunches. The feasibility of the idea was first examined by computer simulation of the electron motion in a 5 MW klystron and the characteristics of the klystron spent beam. Experimental study was then carried out by installing a radio frequency cavity and a Faraday cage in sequence at the exit end of a bending magnet located at the top of the klystron collector. The energy and current of the chopped spent electron beam can then be measured. By properly choosing the feedback circuit elements, the frequency stability of the klystron in oscillator mode was proved to be good enough for linac operation. According to the results presented in this article, it is evident that an extremely compact linac for research and education with better affordability can be constructed to promote the applications of linacs

  14. A modified space charge routine for high intensity bunched beams

    International Nuclear Information System (INIS)

    Lapostolle, P.; Garnett, R.W.; Wangler, T.P.

    1996-01-01

    In 1991 a space charge calculation for bunched beam with a three-dimensional ellipsoid was proposed, replacing the usual SCHEFF routines. It removes the cylindrical symmetry required in SCHEFF and avoids the point to point interaction computation, whose number of simulation points is limited. This routine has now been improved with the introduction of two or three ellipsoids giving a good representation of the complex non-symmetrical form of the bunch (unlike the 3-d ellipsoidal assumption). The ellipsoidal density distributions are computed with a new method, avoiding the difficulty encountered near the centre (the axis in 2-d problems) by the previous method. It also provides a check of the ellipsoidal symmetry for each part of the distribution. Finally, the Fourier analysis reported in 1991 has been replaced by a very convenient Hermite expansion, which gives a simple but accurate representation of practical distributions. Comparisons with other space charge routines have been made, particularly with the ones applying other techniques such as SCHEFF. Introduced in the versatile beam dynamics code DYNAC, it should provide a good tool for the study of the various parameters responsible for the halo formation in high intensity linacs. (orig.)

  15. Violence Patterns in Peckinpah's The Wild Bunch (1969: Critical Reading

    Directory of Open Access Journals (Sweden)

    Baker Bani-Khair

    2017-03-01

    Full Text Available This paper focuses on the issue of violence in Sam Peckinpah's The Wild Bunch (1969 through explaining some of the cultural and historical implications of violence in the 1960s such as Vietnam War, the Mexican war and also the explosion of the feminist movement and some other important social and political upheavals that shaped the cultural context of the 1960s in America. It also sheds light on Sam Peckinpah’s approach of violence screen and stylizing violence and the representations of violence as a tormenting and brutalizing reality that matches the spirit of the age in addition to the social, political, and colonial conflicts of the 1960s. Violence and the implications of violence in The Wild Bunch whether social , cultural, psychological, or humanistic have been discussed in brief in order to show the critical approach of the film as being a rich and didactic film to watch, especially in terms of its rich cultural and historical contexts.

  16. Generation of ultra-short relativistic-electron-bunch by a laser wakefield

    NARCIS (Netherlands)

    Khachatryan, A.G.; Boller, Klaus J.; van Goor, F.A.

    2003-01-01

    The possibility of the generation of an ultra-short (about one micron long) relativistic (up to a few GeVs) electron-bunch in a moderately nonlinear laser wakefield excited in an underdense plasma by an intense laser pulse is investigated. The ultra-short bunch is formed by trapping, effective

  17. Investigation of focusing of relativistic electron and positron bunches moving in cold plasma. Final report

    International Nuclear Information System (INIS)

    Amatuni, A.Ts.; Elbakian, S.S.; Khachatryan, A.G.; Sekhpossian, E.V.

    1995-03-01

    This document is the final report on a project to study focusing effects of relativistic beams of electrons and positrons interacting with a cold plasma. The authors consider three different models for the overdense cold plasma - electron bunch interaction. They look at coulomb effects, wakefield effects, bunch parameters, and the effects of trains of pulses on focusing properties

  18. Beam-Beam Interaction, Electron Cloud and Intrabeam Scattering for Proton Super-bunches

    CERN Document Server

    Ruggiero, F; Rumolo, Giovanni; Papaphilippou, Y

    2003-01-01

    Super-bunches are long bunches with a flat longitudinal profile, which could potentially increase the LHC luminosity in a future upgrade. We present example parameters and discuss a variety of issues related to such superbunches, including beam-beam tune shift, tune footprints, crossing schemes, luminosity, intrabeam scattering, and electron cloud. We highlight the benefits, disadvantages and open questions.

  19. A Value-Engaged Approach for Evaluating the Bunche-Da Vinci Learning Academy

    Science.gov (United States)

    Greene, Jennifer C.

    2005-01-01

    In 2001, the Bunche Academy was chosen by its district to join in partnership with the Da Vinci Learning Corporation to embark on an ambitious whole-school reform initiative, especially designed by the corporation for low-performing schools. In this chapter, the author describes how, as illustrated in the Bunche-Da Vinci Learning Academy context,…

  20. A Proposal to Build Evaluation Capacity at the Bunche-Da Vinci Learning Partnership Academy

    Science.gov (United States)

    King, Jean A.

    2005-01-01

    The author describes potential evaluation capacity-building activities in contrast to the specifics of an evaluation design. Her response to the case of the Bunche-Da Vinci Learning Partnership Academy is developed in three parts: (1) an initial framing of the Bunche-Da Vinci situation; (2) what should be done before signing a contract; and (3)…

  1. The excitation of wakefield in plasma by the sequence of electron bunches

    International Nuclear Information System (INIS)

    Onishchenko, I.N.; Balakirev, V.A.; Berezin, A.K.; Fainberg, J.B.; Kiselyov, V.A.; Linnik, A.F.; Sidel'nikov, G.L.; Sotnikov, G.V.; Uskov, V.V.

    1994-01-01

    The theoretical and experimental investigations of wakefield excitation in plasma by the train of bunches were carried out. The dependence of the wakefield amplitude on the number of bunches was considered and the saturation mechanism was determined. (author). 6 refs, 3 figs

  2. Acceleration of electrons at wakefield excitation by a sequence of relativistic electron bunches in dielectric resonator

    International Nuclear Information System (INIS)

    Kiselev, V.A.; Linnik, A.F.; Mirnyj, V.I.; Onishchenko, I.N.; Uskov, V.V.

    2009-01-01

    Method is proposed to divide a regular sequence of electron bunches into parts of bunches driving wakefield and witness bunches, which should be accelerated. It allows to avoid the necessity of additional electron accelerator for witness bunches producing and the necessity of precision short time techniques of injection phase adjusting. The idea concludes to the frequency detuning between bunches repetition frequency and the frequency of the fundamental mode of excited wakefield. Experiments were carried out on the linear resonant accelerator 'Almaz-2', which injected in the dielectric resonator a sequence of 6000 short bunches of relativistic electrons with energy 4.5 MeV, charge 0.16 nC and duration 60 psec each, the repetition interval 360 ps. Frequency detuning was entered by change of frequency of the master generator of the klystron within the limits of one percent so that the phase taper on the length of bunches sequence achieved 2π. Energy spectra of electrons of bunches sequence, which have been propagated through the dielectric resonator are measured and analyzed

  3. Nonlinear coherent beam-beam oscillations in the rigid bunch model

    International Nuclear Information System (INIS)

    Dikansky, N.; Pestrikov, D.

    1990-01-01

    Within the framework of the rigid bunch model coherent oscillations of strong-strong colliding bunches are described by equations which are specific for the weak-strong beam case. In this paper some predictions of the model for properties of nonlinear coherent oscillations as well as for associated limitations of the luminosity are discussed. 14 refs.; 6 figs

  4. Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation

    International Nuclear Information System (INIS)

    Hugo, Honor J; Wafai, Razan; Blick, Tony; Thompson, Erik W; Newgreen, Donald F

    2009-01-01

    A feature of epithelial to mesenchymal transition (EMT) relevant to tumour dissemination is the reorganization of actin cytoskeleton/focal contacts, influencing cellular ECM adherence and motility. This is coupled with the transcriptional repression of E-cadherin, often mediated by Snail1, Snail2 and Zeb1/δEF1. These genes, overexpressed in breast carcinomas, are known targets of growth factor-initiated pathways, however it is less clear how alterations in ECM attachment cross-modulate to regulate these pathways. EGF induces EMT in the breast cancer cell line PMC42-LA and the kinase inhibitor staurosporine (ST) induces EMT in embryonic neural epithelial cells, with F-actin de-bundling and disruption of cell-cell adhesion, via inhibition of aPKC. PMC42-LA cells were treated for 72 h with 10 ng/ml EGF, 40 nM ST, or both, and assessed for expression of E-cadherin repressor genes (Snail1, Snail2, Zeb1/δEF1) and EMT-related genes by QRT-PCR, multiplex tandem PCR (MT-PCR) and immunofluorescence +/- cycloheximide. Actin and focal contacts (paxillin) were visualized by confocal microscopy. A public database of human breast cancers was assessed for expression of Snail1 and Snail2 in relation to outcome. When PMC42-LA were treated with EGF, Snail2 was the principal E-cadherin repressor induced. With ST or ST+EGF this shifted to Snail1, with more extreme EMT and Zeb1/δEF1 induction seen with ST+EGF. ST reduced stress fibres and focal contact size rapidly and independently of gene transcription. Gene expression analysis by MT-PCR indicated that ST repressed many genes which were induced by EGF (EGFR, CAV1, CTGF, CYR61, CD44, S100A4) and induced genes which alter the actin cytoskeleton (NLF1, NLF2, EPHB4). Examination of the public database of breast cancers revealed tumours exhibiting higher Snail1 expression have an increased risk of disease-recurrence. This was not seen for Snail2, and Zeb1/δEF1 showed a reverse correlation with lower expression values being predictive

  5. Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation

    Directory of Open Access Journals (Sweden)

    Thompson Erik W

    2009-07-01

    Full Text Available Abstract Background A feature of epithelial to mesenchymal transition (EMT relevant to tumour dissemination is the reorganization of actin cytoskeleton/focal contacts, influencing cellular ECM adherence and motility. This is coupled with the transcriptional repression of E-cadherin, often mediated by Snail1, Snail2 and Zeb1/δEF1. These genes, overexpressed in breast carcinomas, are known targets of growth factor-initiated pathways, however it is less clear how alterations in ECM attachment cross-modulate to regulate these pathways. EGF induces EMT in the breast cancer cell line PMC42-LA and the kinase inhibitor staurosporine (ST induces EMT in embryonic neural epithelial cells, with F-actin de-bundling and disruption of cell-cell adhesion, via inhibition of aPKC. Methods PMC42-LA cells were treated for 72 h with 10 ng/ml EGF, 40 nM ST, or both, and assessed for expression of E-cadherin repressor genes (Snail1, Snail2, Zeb1/δEF1 and EMT-related genes by QRT-PCR, multiplex tandem PCR (MT-PCR and immunofluorescence +/- cycloheximide. Actin and focal contacts (paxillin were visualized by confocal microscopy. A public database of human breast cancers was assessed for expression of Snail1 and Snail2 in relation to outcome. Results When PMC42-LA were treated with EGF, Snail2 was the principal E-cadherin repressor induced. With ST or ST+EGF this shifted to Snail1, with more extreme EMT and Zeb1/δEF1 induction seen with ST+EGF. ST reduced stress fibres and focal contact size rapidly and independently of gene transcription. Gene expression analysis by MT-PCR indicated that ST repressed many genes which were induced by EGF (EGFR, CAV1, CTGF, CYR61, CD44, S100A4 and induced genes which alter the actin cytoskeleton (NLF1, NLF2, EPHB4. Examination of the public database of breast cancers revealed tumours exhibiting higher Snail1 expression have an increased risk of disease-recurrence. This was not seen for Snail2, and Zeb1/δEF1 showed a reverse

  6. A study of fast bunch rotation in the negative mass region

    CERN Document Server

    Rumolo, Giovanni

    2001-01-01

    Fast bunch rotation of high-intensity proton or ion bunches above transition is - in principle - supported by the self-bunching effect of the attractive space charge force ("negative instabilities"). Due to the broad-band nature of the space charge impedance, the highest harmonics of this negative mass mode grow fast and inhibit compression, unless the bunch rotation is accelerated by a sufficiently high rf-voltage. Using particle-in-cell simulation we establish the threshold below which effective compression is still possible. We find that the required rf-voltage for compression of a given bunch above transition can be reduced at most by a factor 2 compared with compression below transition, where space charge requires extra voltage.

  7. Beam simulations with initial bunch noise in superconducting RF proton linacs

    CERN Document Server

    Tückmantel, J

    2010-01-01

    Circular machines are plagued by coupled bunch instabilities (CBI), driven by impedance peaks, where then all cavity higher order modes (HOMs) are possible drivers. Limiting the CBI growth rate is the fundamental reason that all superconducting rf cavities in circular machines are equipped with HOM dampers. The question arises if for similar reasons HOM damping would not be imperative also in high current superconducting rf proton linacs. Therefore we have simulated the longitudinal bunched beam dynamics in such machines, also including charge and position noise on the injected bunches. Simulations were executed for a generic linac with properties close to the planned SPL at CERN, SNS, or Project X at FNAL. It was found that with strong bunch noise and monopole HOMs with high Qext large beam scatter, possibly exceeding the admittance of a receiving machine, cannot be excluded. A transverse simulation shows similar requirements. Therefore including initial bunch noise in any beam dynamic study on superconducti...

  8. Radial bunch compression: Path-length compensation in an rf photoinjector with a curved cathode

    Directory of Open Access Journals (Sweden)

    M. J. de Loos

    2006-08-01

    Full Text Available Electron bunch lengthening due to space-charge forces in state-of-the-art rf photoinjectors limits the minimum bunch length attainable to several hundreds of femtoseconds. Although this can be alleviated by increasing the transverse dimension of the electron bunch, a larger initial radius causes path-length differences in both the rf cavity and in downstream focusing elements. In this paper we show that a curved cathode virtually eliminates these undesired effects. Detailed numerical simulations confirm that significantly shorter bunches are produced by an rf photogun with a curved cathode compared to a flat cathode device. The proposed novel method will be used to provide 100 fs duration electron bunches for injection into a laser-driven plasma wakefield accelerator.

  9. An Electron Bunch Compression Scheme for a Superconducting Radio Frequency Linear Accelerator Driven Light Source

    Energy Technology Data Exchange (ETDEWEB)

    C. Tennant, S.V. Benson, D. Douglas, P. Evtushenko, R.A. Legg

    2011-09-01

    We describe an electron bunch compression scheme suitable for use in a light source driven by a superconducting radio frequency (SRF) linac. The key feature is the use of a recirculating linac to perform the initial bunch compression. Phasing of the second pass beam through the linac is chosen to de-chirp the electron bunch prior to acceleration to the final energy in an SRF linac ('afterburner'). The final bunch compression is then done at maximum energy. This scheme has the potential to circumvent some of the most technically challenging aspects of current longitudinal matches; namely transporting a fully compressed, high peak current electron bunch through an extended SRF environment, the need for a RF harmonic linearizer and the need for a laser heater. Additional benefits include a substantial savings in capital and operational costs by efficiently using the available SRF gradient.

  10. Study on Handing Process and Quality Degradation of Oil Palm Fresh Fruit Bunches (FFB)

    Science.gov (United States)

    Mat Sharif, Zainon Binti; Taib, Norhasnina Binti Mohd; Yusof, Mohd Sallehuddin Bin; Rahim, Mohammad Zulafif Bin; Tobi, Abdul Latif Bin Mohd; Othman, Mohd Syafiq Bin

    2017-05-01

    The main objective of this study is to determine the relationship between quality of oil palm fresh fruit bunches (FFB) and handling processes. The study employs exploratory and descriptive design, with quantitative approach and purposive sampling using self-administrated questionnaires, were obtained from 30 smallholder respondents from the Southern Region, Peninsular Malaysia. The study reveals that there was a convincing relationship between quality of oil palm fresh fruit bunches (FFB) and handling processes. The main handling process factors influencing quality of oil palm fresh fruit bunches (FFB) were harvesting activity and handling at the plantation area. As a result, it can be deduced that the handling process factors variable explains 82.80% of the variance that reflects the quality of oil palm fresh fruit bunches (FFB). The overall findings reveal that the handling process factors do play a significant role in the quality of oil palm fresh fruit bunches (FFB).

  11. Dynamics of electron bunches at the laser–plasma interaction in the bubble regime

    Energy Technology Data Exchange (ETDEWEB)

    Maslov, V.I., E-mail: vmaslov@kipt.kharkov.ua; Svystun, O.M., E-mail: svistun_elena@mail.ru; Onishchenko, I.N.; Tkachenko, V.I.

    2016-09-01

    The multi-bunches self-injection, observed in laser–plasma accelerators in the bubble regime, affects the energy gain of electrons accelerated by laser wakefield. However, understanding of dynamics of the electron bunches formed at laser–plasma interaction may be challenging. We present here the results of fully relativistic electromagnetic particle-in-cell (PIC) simulation of laser wakefield acceleration driven by a short laser pulse in an underdense plasma. The trapping and acceleration of three witness electron bunches by the bubble-like structures were observed. It has been shown that with time the first two witness bunches turn into drivers and contribute to acceleration of the last witness bunch.

  12. Mutual compensation of wakefield and chromatic effects of intense linac bunches

    International Nuclear Information System (INIS)

    Seeman, J.T.; Merminga, N.

    1990-05-01

    Mutual compensation of transverse and chromatic effects for intense electron bunches in a high-energy linac is a recent Novosibirsk idea which provides a new control of emittance enlargement. In this paper we elaborate on the principles and constraints for this new technique which requires careful matching of internal bunch parameters with external forces. With species values of the bunch length, bunch intensity, and klystron phasing, the transverse-wakefield-induced forces within the bunch can be cancelled by energy-dependent forces from the quadrupole lattice at all positions along the linac. Under these conditions the tolerances for quadrupole alignment, dipole stability, and injection launch errors are significantly relaxed. 7 refs., 8 figs

  13. Nonlinear electrostatic emittance compensation in kA, fs electron bunches

    International Nuclear Information System (INIS)

    Geer, S.B. van der; Loos, M.J. de; Botman, J.I.M.; Luiten, O.J.; Wiel, M.J. van der

    2002-01-01

    Nonlinear space-charge effects play an important role in emittance growth in the production of kA electron bunches with a bunch length much smaller than the bunch diameter. We propose a scheme employing the radial third-order component of an electrostatic acceleration field, to fully compensate the nonlinear space-charge effects. This results in minimal transverse root-mean-square emittance. The principle is demonstrated using our design simulations of a device for the production of high-quality, high-current, subpicosecond electron bunches using electrostatic acceleration in a 1 GV/m field. Simulations using the GPT code produce a bunch of 100 pC and 73 fs full width at half maximum pulse width, resulting in a peak current of about 1.2 kA at an energy of 2 MeV. The compensation scheme reduces the root-mean-square emittance by 34% to 0.4π mm mrad

  14. Single-shot electro-optic experiments for electron bunch diagnostics at Tsinghua Accelerator Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Wei; Du, Yingchao; Yan, Lixin; Hua, Jianfei; Zhang, Zhen; Zhou, Zheng [Accelerator Laboratory, Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle and Radiation Imaging, Tsinghua University, Ministry of Education, Beijing 100084 (China); Huang, Wenhui, E-mail: huangwh@mail.tsinghua.edu.cn [Accelerator Laboratory, Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle and Radiation Imaging, Tsinghua University, Ministry of Education, Beijing 100084 (China); Tang, Chuanxiang [Accelerator Laboratory, Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Key Laboratory of Particle and Radiation Imaging, Tsinghua University, Ministry of Education, Beijing 100084 (China); Li, Ming [Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900 (China)

    2016-10-21

    The electro-optic (EO) technique detects the Coulomb electric field distribution of relativistic electron bunches to obtain the associated longitudinal profile. This diagnostic method allows the direct time-resolved single-shot measurement and thus the real-time monitoring of the bunch profile and beam arrival time in a non-destructive way with sub-picosecond temporal resolution. In this paper, we report the measurement of the longitudinal profile of an electron bunch through electro-optic spectral decoding detection, in which the bunch profile is encoded into the spectra of the linearly chirped laser pulse. The experimental setup and measurement results of a 40 MeV electron bunch are presented, with a temporal profile length of 527 fs rms (~1.24 ps FWHM) and a beam arrival time jitter of 471 fs rms. Temporal resolution and future experimental improvement are also discussed.

  15. Stability of higher-order longitudinal modes in a bunched beam without mode coupling

    International Nuclear Information System (INIS)

    Satoh, K.

    1981-05-01

    The theory of longitudinal instabilities of bunched beams was proposed by F. Sacherer. Starting from the Vlasov equation, he derived the integral equation for the perturbed distribution function. While the general method to solve the integral equation was given by Sacherer, a number of other papers discussing longitudinal bunched beam instability have also been published. Here we want to propose another formalism with which we can treat the integral equation without mode coupling for the case of a Gaussian bunch. We then generalize the formalism for the other bunch distributions, and derive a practical method to analyze the instability for the case of a parabolic bunch. While the solution of the Sacherer equation that we find is not new, we present another approach to solve it. Since the integral equation for the transverse instability is similar to that for the longitudinal instability, this formalism is also useful for the transverse case. 12 figs., 4 figs

  16. Bunch Compressor Beamlines for the Tesla and S Band Linear Colliders

    CERN Document Server

    Emma, P

    2003-01-01

    A detailed design for a single stage beam bunch length compressor for both the TESLA and the S-Band Linear Collider (SBLC) is presented. Compression is achieved by introducing an energy-position correlation along the bunch with an rf section at zero-crossing phase followed by a short bending section with energy dependent path length (momentum compaction). The motivation for a wiggler design is presented and many of the critical single bunch tolerances are evaluated. A solenoid based spin rotator is included in the design and transverse emittance tuning elements, diagnostics and tuning methods are described. Bunch length limitations due to second order momentum compaction and sinusoidal rf shape are discussed with options for compensation. Finally, the disadvantages of bunch compression using a 180 sup o arc are discussed.

  17. Bunch compression efficiency of the femtosecond electron source at Chiang Mai University

    International Nuclear Information System (INIS)

    Thongbai, C.; Kusoljariyakul, K.; Saisut, J.

    2011-01-01

    A femtosecond electron source has been developed at the Plasma and Beam Physics Research Facility (PBP), Chiang Mai University (CMU), Thailand. Ultra-short electron bunches can be produced with a bunch compression system consisting of a thermionic cathode RF-gun, an alpha-magnet as a magnetic bunch compressor, and a linear accelerator as a post acceleration section. To obtain effective bunch compression, it is crucial to provide a proper longitudinal phase-space distribution at the gun exit matched to the subsequent beam transport system. Via beam dynamics calculations and experiments, we investigate the bunch compression efficiency for various RF-gun fields. The particle distribution at the RF-gun exit will be tracked numerically through the alpha-magnet and beam transport. Details of the study and results leading to an optimum condition for our system will be presented.

  18. Bunch compression efficiency of the femtosecond electron source at Chiang Mai University

    Science.gov (United States)

    Thongbai, C.; Kusoljariyakul, K.; Saisut, J.

    2011-07-01

    A femtosecond electron source has been developed at the Plasma and Beam Physics Research Facility (PBP), Chiang Mai University (CMU), Thailand. Ultra-short electron bunches can be produced with a bunch compression system consisting of a thermionic cathode RF-gun, an alpha-magnet as a magnetic bunch compressor, and a linear accelerator as a post acceleration section. To obtain effective bunch compression, it is crucial to provide a proper longitudinal phase-space distribution at the gun exit matched to the subsequent beam transport system. Via beam dynamics calculations and experiments, we investigate the bunch compression efficiency for various RF-gun fields. The particle distribution at the RF-gun exit will be tracked numerically through the alpha-magnet and beam transport. Details of the study and results leading to an optimum condition for our system will be presented.

  19. Radiative interaction of electrons in a short electron bunch moving in an undulator

    International Nuclear Information System (INIS)

    Saldin, E. L.; Schneidmiller, E. A.; Yurkov, M. V.

    1999-01-01

    This paper presents investigations of the longitudinal radiative force in an electron bunch. The model of the electron bunch assumes line density distribution. General formulas are presented for the calculation of the radiative force in the bunch moving along an arbitrary small-angle trajectory. The case of a motion in an undulator (wiggler) has been studied in detail. Analytical solutions are obtained for a rectangular and for a Gaussian bunch shape. It is shown that the rate of the bunch energy loss due to the radiative interaction is equal to the power of the coherent radiation in the far zone. Numerical estimations presented in the paper show that the effects of induced energy spread due to the radiative interaction can be important for free electron lasers operating in the infrared wavelength range

  20. Tunable Subpicosecond Electron-Bunch-Train Generation Using a Transverse-To-Longitudinal Phase-Space Exchange Technique

    International Nuclear Information System (INIS)

    Sun, Y.-E; Piot, P.; Maxwell, T. J.; Johnson, A.; Lumpkin, A. H.; Ruan, J.; Thurman-Keup, R.

    2010-01-01

    We report on the experimental generation of a train of subpicosecond electron bunches. The bunch train generation is accomplished using a beam line capable of exchanging the coordinates between the horizontal and longitudinal degrees of freedom. An initial beam consisting of a set of horizontally separated beamlets is converted into a train of bunches temporally separated with tunable bunch duration and separation. The experiment reported in this Letter unambiguously demonstrates the conversion process and its versatility.

  1. RF acceleration of intense laser generated proton bunches

    Energy Technology Data Exchange (ETDEWEB)

    Almomani, Ali

    2012-07-13

    With respect to laser-accelerated beams, the high current capability of the CH-DTL cavity has been investigated. Beam simulations have demonstrated that 10{sup 10} protons per bunch can be accelerated successfully and loss free along the structure. It was shown that, the maximum number of protons per bunch that can be accelerated in the first cavity by exploiting about 1% of the stored field energy is 2.02 x 10{sup 11} protons. One further aspect is the total number of protons arriving at the linac entrance. One main aspect of an rf postacceleration experiment is the rf operation stability under these beam load conditions. Detailed simulations from the target along the solenoid and down to the linac entrance were presented, applying adapted software. Special care was taken on the time steps, especially close to the target, and on the collective phenomena between electron and proton distributions. The effect of comoving electrons on the beam dynamics has been investigated in detail. A CH-linac with high space charge limit and large transverse and longitudinal acceptance was designed to accept a maximum fraction of the laser generated proton bursts. Due to well-known transformations of the injected beam emittances along the CH-cavity, it is aimed to derive parameters of the laser generated beam by measuring the beam properties behind of the CH-cavity. With respect to the linac development it is intended to realize the first cavity of the proposed CH-DTL and to demonstrate the acceleration of a laser generated proton bunch with the LIGHT project. The first cavity consists of 7 gaps within a total length of about 668 mm. It is operated at 325 MHz and has an effective accelerating field gradient of about 12.6 MV/m. The study on the surface electric field for this cavity shows, that maximum surface fields of about 94 MV/m and 88 MV/m on the third and sixth drift tubes are reachable, respectively.

  2. The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFκB signaling pathway and nitric oxide induction in macrophages

    Directory of Open Access Journals (Sweden)

    Sredni Benjamin

    2010-01-01

    Full Text Available Abstract Background LPS-activated macrophages produce mediators which are involved in inflammation and tissue injury, and especially those associated with endotoxic shock. The non toxic tellurium compound ammonium tri-chloro(dioxoethylene-O,O'-tellurate, AS101, has been recently shown to exert profound anti-inflammatory properties in animal models, associated with its Te(IV redox chemistry. This study explores the anti-inflammatory properties of AS101 with respect to modulation of inflammatory cytokines production and regulation of iNOS transcription and expression in activated macrophages via targeting the NFkB complex. Results AS101 decreased production of IL-6 and in parallel down-regulated LPS-induced iNOS expression and NO secretion by macrophages. AS101 reduced IkB phosphorylation and degradation, and reduced NFkB nuclear translocalization, albeit these effects were exerted at different kinetics. Chromatin immunoprecipitation assays showed that AS101 treatment attenuated p50-subunit ability to bind DNA at the NFkB consensus site in the iNOS promotor following LPS induction. Conclusions Besides AS101, the investigation of therapeutic activities of other tellurium(IV compounds is scarce in the literature, although tellurium is the fourth most abundant trace element in the human body. Since IKK and NFkB may be regulated by thiol modifications, we may thus envisage, inview of our integrated results, that Te(IV compounds, may have important roles in thiol redox biological activity in the human body and represent a new class of anti-inflammatory compounds.

  3. Gridded thermionic gun and integral superconducting ballistic bunch compression cavity

    Energy Technology Data Exchange (ETDEWEB)

    Schultheiss, Thomas [Advanced Energy Systems, Inc., Medford, NY (United States)

    2015-11-16

    Electron-Ion colliders such as the Medium energy Electron Ion Collider (MEIC) being developed by JLAB require high current electrons with low energy spread for electron cooling of the collider ring. Accelerator techniques for improving bunch charge, average current, emittance, and energy spread are required for Energy Recovery Linacs (ERLs) and Circulator Rings (CR) for next generation colliders for nuclear physics experiments. Example candidates include thermionic-cathode electron guns with RF accelerating structures. Thermionic cathodes are known to produce high currents and have excellent lifetime. The success of the IR and THz Free-Electron Laser (FEL) designed and installed by Advanced Energy Systems at the Fritz Haber Institute (FHI) of the Max Planck Society in Berlin [1,2] demonstrates that gridded thermionic cathodes and rf systems be considered for next generation collider technology. In Phase 1 Advanced Energy Systems (AES) developed and analyzed a design concept using a superconducting cavity pair and gridded thermionic cathode. Analysis included Beam Dynamics and thermal analysis to show that a design of this type is feasible. The latest design goals for the MEIC electron cooler were for electron bunches of 420 pC at a frequency of 952.6 MHz with a magnetic field on the cathode of 2kG. This field magnetizes the beam imparting angular momentum that provides for helical motion of the electrons in the cooling solenoid. The helical motion increases the interaction time and improves the cooling efficiency. A coil positioned around the cathode providing 2kG field was developed. Beam dynamics simulations were run to develop the particle dynamics near the cathode and grid. Lloyd Young added capability to Tstep to include space charge effects between two plates and include image charge effects from the grid. He also added new pepper-pot geometry capability to account for honeycomb grids. These additions were used to develop the beam dynamics for this gun. The

  4. Estimates of post-acceleration longitudinal bunch compression

    International Nuclear Information System (INIS)

    Judd, D.L.

    1977-01-01

    A simple analytic method is developed, based on physical approximations, for treating transient implosive longitudinal compression of bunches of heavy ions in an accelerator system for ignition of inertial-confinement fusion pellet targets. Parametric dependences of attainable compressions and of beam path lengths and times during compression are indicated for ramped pulsed-gap lines, rf systems in storage and accumulator rings, and composite systems, including sections of free drift. It appears that for high-confidence pellets in a plant producing 1000 MW of electric power the needed pulse lengths cannot be obtained with rings alone unless an unreasonably large number of them are used, independent of choice of rf harmonic number. In contrast, pulsed-gap lines alone can meet this need. The effects of an initial inward compressive drift and of longitudinal emittance are included

  5. Analytical formulas for short bunch wakes in a flat dechirper

    Energy Technology Data Exchange (ETDEWEB)

    Bane, Karl; Stupakov, Gennady [SLAC National Accelerator Laboratory, Menlo Park, CA (United States); Zgorodnov, Igor [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2016-03-15

    We develop analytical models of the longitudinal and transverse wakes, on and off axis for realistic structures, and then compare them with numerical calculations, and generally find good agreement. These analytical ''first order'' formulas approximate the droop at the origin of the longitudinal wake and of the slope of the transverse wakes; they represent an improvement in accuracy over earlier, ''zeroth order'' formulas. In example calculations for the RadiaBeam/LCLS dechirper using typical parameters, we find a 16% droop in the energy chirp at the bunch tail compared to simpler calculations. With the beam moved to 200 μm from one jaw in one dechirper section, one can achieve a 3 MV transverse kick differential over a 30 μm length.

  6. Single bunch transfer system for the National Synchrotron Light Source

    International Nuclear Information System (INIS)

    Sheehan, J.; Singh, O.; Rambo, W.

    1983-01-01

    The accelerator system at the National Synchrotron Light Source consists of an S-band 85 MeV linac and three synchrotron rings. The electron beam from the linac is accelerated by the booster ring to 600 MeV and transferred to one of the two storage rings. The smaller of the two rings operates between 300 and 800 MeV emtting photons in the vacuum ultraviolet (VUV), while the larger storage ring operates up to 2.5 GeV and emits photons in the x-ray spectrum. A system is described for loading the storage rings by filling a single-phase space bunch in the booster ring and transferring it at the end of each booster cycle into a selected bucket in one of the storage rings. By controlling the timing of the transfer on successive transfer cycles, many fill patterns may be obtained

  7. Bunching phase evolution of short-pulse FEL oscillator system

    CERN Document Server

    Song, S B; Choi, D I

    2000-01-01

    We studied numerically the short-pulse FEL oscillator system using properly defined bunching phase theta sub B and PSI sub B. In stable operation, we have found that the optical field 'locks' the phase to pi/2 at the trailing edge, which gives the maximum gain. Moreover, electrons can be detrapped from ponderomotive bucket due to the spatial variation of the optical field, and this detrapping effect is a major cause of the limit cycle oscillation of the system. The 'bump' of the output power during the amplification usually exists at the near-perfect cavity synchronism regime, which can be explained as the change of the matching condition between electron micropulse and optical pulse.

  8. Single-Bunch Stability With Direct Space Charge

    CERN Multimedia

    Oeftiger, Adrian

    2017-01-01

    Previous studies have shown the suppressing effect of direct space charge on impedance-driven head-tail instabilities. The present work investigates transverse stability for the HL-LHC scenario based on our macro-particle simulation tool PyHEADTAIL using realistic bunch distributions. The impact of selfconsistent modelling is briefly discussed for non-linear space charge forces. We study how space charge pushes the instability threshold for the transverse mode coupling instability (TMCI) occurring between mode 0 and -1. Next we consider finite chromaticity: in absence of space charge, the impedance model predicts head-tail instabilities. For a selected case below TMCI threshold at Q0 = 5, we demonstrate the stabilising effect of space charge. Finally, we compare simulation results to past LHC measurements.

  9. Bunching and cooling of radioactive ions with REXTRAP

    CERN Document Server

    Schmidt, P; Bollen, G; Forstner, O; Huber, G; Oinonen, M; Zimmer, J

    2002-01-01

    The post-accelerator REX-ISOLDE at ISOLDE/CERN will deliver radioactive ion beams with energies up to 2.2 MeV/u. For this purpose, a Penning trap and an electron-beam ion source are combined with a linear accelerator. REXTRAP—a large gas-filled Penning trap—has started its commissioning phase. First tests have shown that REXTRAP is able to accumulate, cool and bunch stable ISOLDE ion beams covering a large mass range. Fulfilling the REX-ISOLDE demands, it can handle beam intensities from a few hundred up to 1×10 6 ions per pulse at repetition rates up to 50 Hz.

  10. Analytical formulas for short bunch wakes in a flat dechirper

    International Nuclear Information System (INIS)

    Bane, Karl; Stupakov, Gennady; Zgorodnov, Igor

    2016-03-01

    We develop analytical models of the longitudinal and transverse wakes, on and off axis for realistic structures, and then compare them with numerical calculations, and generally find good agreement. These analytical ''first order'' formulas approximate the droop at the origin of the longitudinal wake and of the slope of the transverse wakes; they represent an improvement in accuracy over earlier, ''zeroth order'' formulas. In example calculations for the RadiaBeam/LCLS dechirper using typical parameters, we find a 16% droop in the energy chirp at the bunch tail compared to simpler calculations. With the beam moved to 200 μm from one jaw in one dechirper section, one can achieve a 3 MV transverse kick differential over a 30 μm length.

  11. Emittance Correction in the 2006 ILC Bunch Compressor

    International Nuclear Information System (INIS)

    Tenenbaum, P.; SLAC

    2007-01-01

    A recent study [1] has indicated substantial potential emittance growth in the ILC bunch compressor due to quad misalignments, BPM misalignments, and pitches in the RF cavities. Table 1 summarizes several results from [1]. In this simulation, quad misalignments and cavity pitches are Gaussian distributed and are considered with respect to the nominal survey line; BPM misalignments are also Gaussian-distributed but are considered with respect to the quadrupole axis. It is assumed that the BPM offsets with respect to the quads are found in a previous quad-shunting BBA step which is not simulated. In this study we seek to repeat the studies documented above, and additionally to perform a study in which additional dispersion bumps are used to further reduce the projected emittance

  12. Torrefaction of empty fruit bunches under biomass combustion gas atmosphere.

    Science.gov (United States)

    Uemura, Yoshimitsu; Sellappah, Varsheta; Trinh, Thanh Hoai; Hassan, Suhaimi; Tanoue, Ken-Ichiro

    2017-11-01

    Torrefaction of oil palm empty fruit bunches (EFB) under combustion gas atmosphere was conducted in a batch reactor at 473, 523 and 573K in order to investigate the effect of real combustion gas on torrefaction behavior. The solid mass yield of torrefaction in combustion gas was smaller than that of torrefaction in nitrogen. This may be attributed to the decomposition enhancement effect by oxygen and carbon dioxide in combustion gas. Under combustion gas atmosphere, the solid yield for torrefaction of EFB became smaller as the temperature increased. The representative products of combustion gas torrefaction were carbon dioxide and carbon monoxide (gas phase) and water, phenol and acetic acid (liquid phase). By comparing torrefaction in combustion gas with torrefaction in nitrogen gas, it was found that combustion gas can be utilized as torrefaction gas to save energy and inert gas. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Analyzing gigahertz bunch length instabilities with a digital signal processor

    International Nuclear Information System (INIS)

    Stege, R.E. Jr.; Krejcik, P.; Minty, M.G.

    1992-11-01

    A bunch length instability, nicknamed the ''sawtooth'', because of its transient behavior, has been observed at high current running in the Stanford Linear Collider (SLC) electron damping ring. The incompatibility of this instability with successful SLC naming prompted its study using a high bandwidth real-time spectrum analyzer, the Tektronix 3052 digital signal processor (DSP) system. This device has been used to study energy ramping in storage rings but this is the first time it has been used to study transient instability phenomena. It is a particularly valuable tool for use in understanding non-linear, multiple frequency phenomena. The frequency range of this device has been extended through the use of radio frequency (RF) down converters. This paper describes the measurement setup and presents some of the results

  14. Novel beam bunching methods by perfect crystals and electromagnetic means

    International Nuclear Information System (INIS)

    Rauch, H.

    1985-01-01

    The use of perfect crystals for installing new neutron small-angle scattering cameras provides advantages for measurements in the small Q-range and for real-time experiments. A neutron resonator is proposed which is based on the combination of perfect crystal back-reflections in Zeman energy splitting. The neutron magnetic resonance system in combination with gated crystals can act as a pumping unit for neutrons and as a new pulse-shaping unit. It is shown how travelling magnetic waves can act as powerful neutron bunching units. The achievable velocity changes are around 5 m/s and, therefore, by a factor of 100 larger than in the case of neutron magnetic resonance systems. The advantage of expanding potentials for focusing neutrons from a source with a long pulse duration becomes obvious. Real gain factors higher than 10 are expected for properly designed systems. (author)

  15. Electron bunch compression and coherent effects at the SDL

    International Nuclear Information System (INIS)

    Loos, Henrik; Carr, G. Lawrence; Doyuran, Adnan; Graves, William S.; Johnson, Eric D.; Krinsky, Samuel; Rose, James; Sheehy, Brian; Shaftan, Timur V.; Skaritka, John; Yu Lihua

    2002-01-01

    The DUVFEL accelerator in the Source Development Lab of NSLS/BNL generates a high brightness electron beam from a laser driven electron source and a magnetic bunch compressor. This beam is used for different FEL experiments in SASE and future HGHG configurations. The compression of the electron beam to high peak current while preserving the transverse properties is of great importance to the performance goals of these FELs. In this paper we report on the experimental methods to characterize the longitudinal properties of the electron beam and the measured results for various settings of the DUVFEL accelerator. The observed effects on the electron beam spectra and time profiles during compression are most likely due to coherent effects while their exact origin is still subject of ongoing investigation

  16. Nonrelativistic electron bunch train for coherently enhanced terahertz radiation sources

    International Nuclear Information System (INIS)

    Li Yuelin; Kim, Kwang-Je

    2008-01-01

    We propose to generate a train of prebunched electron beams for producing coherently enhanced Smith-Purcell radiation [S. J. Smith and E. M. Purcell, Phys. Rev. 92, 1069 (1953)] in the terahertz wavelength range. In this scheme, a train of picosecond laser pulses is produced to drive a photoemission gun to generate a train of 50 keV electron pulses. The parameters are chosen so that the space-charge effect does not destroy the pulse time structure. Smith-Purcell radiation from the electron pulse train is enhanced due both to the short length of the individual electron bunch and to the repetitive structure of the beam. Example systems producing coherent terahertz power at about 1 mW are described

  17. Measuring the electron beam energy in a magnetic bunch compressor

    Energy Technology Data Exchange (ETDEWEB)

    Hacker, Kirsten

    2010-09-15

    Within this thesis, work was carried out in and around the first bunch compressor chicane of the FLASH (Free-electron LASer in Hamburg) linear accelerator in which two distinct systems were developed for the measurement of an electron beams' position with sub-5 {mu}m precision over a 10 cm range. One of these two systems utilized RF techniques to measure the difference between the arrival-times of two broadband electrical pulses generated by the passage of the electron beam adjacent to a pickup antenna. The other system measured the arrival-times of the pulses from the pickup with an optical technique dependent on the delivery of laser pulses which are synchronized to the RF reference of the machine. The relative advantages and disadvantages of these two techniques are explored and compared to other available approaches to measure the same beam property, including a time-of-flight measurement with two beam arrival-time monitors and a synchrotron light monitor with two photomultiplier tubes. The electron beam position measurement is required as part of a measurement of the electron beam energy and could be used in an intra-bunch-train beam-based feedback system that would stabilize the amplitude of the accelerating field. By stabilizing the accelerating field amplitude, the arrival-time of the electron beam can be made more stable. By stabilizing the electron beam arrival-time relative to a stable reference, diagnostic, seeding, and beam-manipulation lasers can be synchronized to the beam. (orig.)

  18. Evaluating oil palm fresh fruit bunch processing in Nigeria.

    Science.gov (United States)

    Anyaoha, Kelechi E; Sakrabani, Ruben; Patchigolla, Kumar; Mouazen, Abdul M

    2018-03-01

    Three routes of oil palm fresh fruit bunch (FFB) processing in Nigeria namely, industrial, small-scale and traditional were compared by means of determining fruit losses associated with each route. The fruits that are not recovered after each process were hand-picked and quantified in terms of crude palm oil (CPO), palm kernel (PK), mesocarp fibre (MF) and palm kernel shell (PKS). The energy value of empty fruit bunch (EFB), MF and PKS were used to determine the value of energy lost for each route. Additionally, the environmental implications of disposal of EFB were estimated, and socio-economics of the industrial and small-scale routes were related. The analysis showed that 29, 18, 75 and 27 kg of CPO, PK, MF and PKS were lost for every 1000 kg of FFB processed with the industrial route, whereas 5.6, 3.2, 1.4 and 5.1 g were lost with the small-scale route, respectively. Approximately 89 kWh and 31 kWh more energy were lost from MF and PKS with the industrial route than the other two routes, respectively. An equivalent of 6670 tonnes carbon dioxide equivalent of methane and nitrogen oxide was released due to the disposal of 29,000 tonnes of EFB from one palm oil mill. The monetary value of lost CPO per 1000 kg of FFB processed in the industrial route is more than the labour cost of processing 1000 kg of FFB in the small-scale route. The advantages of the industrial route are high throughput in terms of FFB processed per hour and high quality of CPO; however, high fruit loss is associated with it and therefore, the poorly threshed EFB is recommended to be fed into the small-scale route.

  19. Hydroxynortriptyline of Empty Fruit Bunches Fibre using Polyethylene glycol (PEG)

    International Nuclear Information System (INIS)

    Noreen, F.M.Z.; Sarani Zakaria

    2013-01-01

    The aim of this study was to investigate the reaction of oil palm empty fruit bunches fibre (EFBF) via chemical modification and hydroxynortriptyline method using polyethylene glycol (PEG). The first stage was the modification of EFB fibre using NaOH and isopropanol. The next stage was the preparation of hydroxypropylated-empty fruit bunches fibre (HP-EFBF), using different molecular weight of PEG (6,000, 8,000 and 10,000). The characterisation involved in this study were conducted by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), thermogravimetry analysis (TGA), determination of kinetic activation energy (E a ), X-ray diffraction (XRD), cellulose crystallinity index (CrI) and weight increment of the HP-EFB fibre. SEM results showed the surface of HP-EFBF swelled and craters formed along the surface of the fibre. IR spectrum also showed OH stretching band in EFB without treatment is 3402 cm -1 , but after hydroxynortriptyline process, the OH stretching band in HP-EFBF (10000, 8000 and 6000) slightly shifted to 3392, 3384 and 3370 cm -1 , respectively. TGA showed the thermal stability of HP-EFBF 6,000 was lower than HP-EFBF 8,000 and 10,000. After chemical modification, the activation energy, E a increased from 32.4 to 51.9 kJ/ mol more than EFB without treatment, 12.5 kJ/ mol. XRD showed that diffraction peak (002) shifted to the smaller 2θ angle and the peaks (101, 10I) disappeared after hydroxynortriptyline process. Crystallinity index, of EFB without treatment decreased from 27 % to 25 % after chemical modification. The higher the molecular weight of the PEG, the greater the weight increment of the HP-EFBF. (author)

  20. VISCOSITY ANALYSIS OF EMPTY FRUIT BUNCH (EFB BIO-OIL

    Directory of Open Access Journals (Sweden)

    Z.S. Nazirah

    2013-12-01

    Full Text Available Empty fruit bunches (EFB are one of the solid wastes produced by the palm oil industry, which is increasing rapidly. The aim of this paper is to analyse the viscosity of empty fruit bunch (EFB bio-oil that can be extracted from all solid waste EFB as a sample, and a few processes were executed. The samples underwent two processes, which were pre-treatment and pyrolysis. The pre-treatment involved three processes, namely, cutting, shredding and sieving, which were necessary in order to prepare EFB into a particle size suitable for the reactor. After that, the samples were fed into the feedback reactor as feedstock for the pyrolysis process to produce bio-oil. Once the bio-oil was produced, its viscosity was tested using the Brookfield Viscometer in two conditions: before and after the chemical reaction. The bio-oil was treated by adding 10 ml and 20 ml of acetone respectively through the chemical reaction. The viscosity test was carried out at different temperatures, which were 25°C, 30°C, 35°C, 40°C, 45°C and 50°C respectively. The observed viscosity of the EFB bio-oil varied and was higher as the temperature decreased. In addition, the viscosity of the EFB bio-oil was higher when it reacted chemically with the acetone added. Therefore, the results showed that the chemical reaction with acetone has the potential to increase the viscosity of EFB bio-oil.

  1. A novel source of MeV positron bunches driven by energetic protons for PAS application

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Zongquan, E-mail: tqq1123@mail.ustc.edu.cn [State Key Laboratory of Particle Detection and Electronics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Xu, Wenzhen; Liu, Yanfen; Xiao, Ran; Kong, Wei [State Key Laboratory of Particle Detection and Electronics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Ye, Bangjiao, E-mail: bjye@ustc.edu.cn [State Key Laboratory of Particle Detection and Electronics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China)

    2014-11-01

    This paper proposes a novel methodology of MeV positrons generation for PAS application. Feasibility of this proposal analyzed by G4Beamline and Transport have shown reasonable success. Using 2 Hz, 1.6 GeV, 100 ns and 1.5 μC/bunch proton bunches for bombarding a graphite target, about 100 ns e{sup +} bunches are generated. Quasi-monochromatic positrons in the range of 1–10 MeV included in these bunches have a flux of >10{sup 7}/s, peak brightness of 10{sup 14}/s. A magnetic-confinement beamline is utilized to transport the positrons and a “Fast Beam Chopper” is unprecedentedly extended to chop those relativistic bunches. The positron beam can be finally characterized by the energy range of 1–10 MeV and bunch width from one hundred ps up to 1 ns. Such ultrashort bunches can be useful in tomography-type positron annihilation spectroscopy (PAS) as well as other applications.

  2. A novel source of MeV positron bunches driven by energetic protons for PAS application

    Science.gov (United States)

    Tan, Zongquan; Xu, Wenzhen; Liu, Yanfen; Xiao, Ran; Kong, Wei; Ye, Bangjiao

    2014-11-01

    This paper proposes a novel methodology of MeV positrons generation for PAS application. Feasibility of this proposal analyzed by G4Beamline and Transport have shown reasonable success. Using 2 Hz, 1.6 GeV, 100 ns and 1.5 μC/bunch proton bunches for bombarding a graphite target, about 100 ns e+ bunches are generated. Quasi-monochromatic positrons in the range of 1-10 MeV included in these bunches have a flux of >107/s, peak brightness of 1014/s. A magnetic-confinement beamline is utilized to transport the positrons and a "Fast Beam Chopper" is unprecedentedly extended to chop those relativistic bunches. The positron beam can be finally characterized by the energy range of 1-10 MeV and bunch width from one hundred ps up to 1 ns. Such ultrashort bunches can be useful in tomography-type positron annihilation spectroscopy (PAS) as well as other applications.

  3. A hybrid approach for generating ultra-short bunches for advanced accelerator applications

    Energy Technology Data Exchange (ETDEWEB)

    Stratakis, Diktys [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2015-09-01

    Generation of electron beams with high phase-space density, short bunch length and high peak current is an essential requirement for future linear colliders and bright electron beam sources. Unfortunately, such bunches cannot be produced directly from the source since forces from the mutual repulsion of electrons would destroy the brilliance of the beam within a short distance. Here, we detail a beam dynamics study of an innovative two-stage compression scheme that can generate ultra-short bunches without degrading the beam quality. In the first stage, the beam is compressed with an advanced velocity bunching technique in which the longitudinal phase space is rotated so that electrons on the bunch tail become faster than electrons in the bunch head. In the second stage, the beam is further compressed with a conventional magnetic chicane. With the aid of numerical simulations we show that our two-staged scheme is capable to increase the current of a 50 pC bunch to a notable factor of 100 while the emittance growth can be suppressed to 1% with appropriate tailoring of the initial beam distribution.

  4. Electron cooling of a bunched ion beam in a storage ring

    Science.gov (United States)

    Zhao, He; Mao, Lijun; Yang, Jiancheng; Xia, Jiawen; Yang, Xiaodong; Li, Jie; Tang, Meitang; Shen, Guodong; Ma, Xiaoming; Wu, Bo; Wang, Geng; Ruan, Shuang; Wang, Kedong; Dong, Ziqiang

    2018-02-01

    A combination of electron cooling and rf system is an effective method to compress the beam bunch length in storage rings. A simulation code based on multiparticle tracking was developed to calculate the bunched ion beam cooling process, in which the electron cooling, intrabeam scattering (IBS), ion beam space-charge field, transverse and synchrotron motion are considered. Meanwhile, bunched ion beam cooling experiments have been carried out in the main cooling storage ring (CSRm) of the Heavy Ion Research Facility in Lanzhou, to investigate the minimum bunch length obtained by the cooling method, and study the dependence of the minimum bunch length on beam and machine parameters. The experiments show comparable results to those from simulation. Based on these simulations and experiments, we established an analytical model to describe the limitation of the bunch length of the cooled ion beam. It is observed that the IBS effect is dominant for low intensity beams, and the space-charge effect is much more important for high intensity beams. Moreover, the particles will not be bunched for much higher intensity beam. The experimental results in CSRm show a good agreement with the analytical model in the IBS dominated regime. The simulation work offers us comparable results to those from the analytical model both in IBS dominated and space-charge dominated regimes.

  5. Fundamental cavity impedance and longitudinal coupled-bunch instabilities at the High Luminosity Large Hadron Collider

    Directory of Open Access Journals (Sweden)

    P. Baudrenghien

    2017-01-01

    Full Text Available The interaction between beam dynamics and the radio frequency (rf station in circular colliders is complex and can lead to longitudinal coupled-bunch instabilities at high beam currents. The excitation of the cavity higher order modes is traditionally damped using passive devices. But the wakefield developed at the cavity fundamental frequency falls in the frequency range of the rf power system and can, in theory, be compensated by modulating the generator drive. Such a regulation is the responsibility of the low-level rf (llrf system that measures the cavity field (or beam current and generates the rf power drive. The Large Hadron Collider (LHC rf was designed for the nominal LHC parameter of 0.55 A DC beam current. At 7 TeV the synchrotron radiation damping time is 13 hours. Damping of the instability growth rates due to the cavity fundamental (400.789 MHz can only come from the synchrotron tune spread (Landau damping and will be very small (time constant in the order of 0.1 s. In this work, the ability of the present llrf compensation to prevent coupled-bunch instabilities with the planned high luminosity LHC (HiLumi LHC doubling of the beam current to 1.1 A DC is investigated. The paper conclusions are based on the measured performances of the present llrf system. Models of the rf and llrf systems were developed at the LHC start-up. Following comparisons with measurements, the system was parametrized using these models. The parametric model then provides a more realistic estimation of the instability growth rates than an ideal model of the rf blocks. With this modeling approach, the key rf settings can be varied around their set value allowing for a sensitivity analysis (growth rate sensitivity to rf and llrf parameters. Finally, preliminary measurements from the LHC at 0.44 A DC are presented to support the conclusions of this work.

  6. Observation of the non colliding bunch parameters evolution in the LHC

    CERN Document Server

    Trad, G

    2012-01-01

    On the 6th and the 7th of June 2011, the LHC was filled so to have twelve additional non-colliding bunches per ring. In this note a detailed observation of the bunch parameters (current, emittances and length) is presented, focusing on the differences in the behaviour between colliding and non-colliding bunches. Lifetimes for the residual gas interaction were estimated. Simulations were compared to the experimental data collected in the MD. Some conclusions are drawn and suggestions for future MD are discussed.

  7. Experimental investigation of the longitudinal beam dynamics in a photoinjector using a two-macroparticle bunch

    Directory of Open Access Journals (Sweden)

    P. Piot

    2006-05-01

    Full Text Available We have developed a two-macroparticle bunch to explore the longitudinal beam dynamics through various components of the Fermilab/NICADD photoinjector. Such a two-macroparticle bunch is generated by splitting the ultraviolet pulse from the photocathode drive laser. The presented method allows the exploration of radio-frequency-induced compression in the 1.625 cell radio frequency gun and the booster cavity. It also allows a direct measurement of the momentum compaction of the magnetic bunch compressor. The measurements are compared with analytical and numerical models.

  8. Three-dimensional nonstationary dynamics of a charged bunches-ellipsoids

    International Nuclear Information System (INIS)

    Budanov, Yu.A.

    2000-01-01

    The work is aimed at studying the changes in the beam dynamics at the beginning of acceleration, when the zero longitudinal emittance is transformed into the final longitudinal phase volume. This process is studied on the bunch-ellipsoid self-consistent model with the charge uniform distribution. The results obtained present the evaluation of the parameters, whereby the longitudinal dynamics in the bunch significantly changes, namely, the particles bunch with increase in the spatial charge transfers into a new state with doubled frequency of the longitudinal oscillations [ru

  9. Quantitative study of the trapped particle bunching instability in Langmuir waves

    International Nuclear Information System (INIS)

    Hara, Kentaro; Boyd, Iain D.; Chapman, Thomas; Joseph, Ilon; Berger, Richard L.; Banks, Jeffrey W.; Brunner, Stephan

    2015-01-01

    The bunching instability of particles trapped in Langmuir waves is studied using Vlasov simulations. A measure of particle bunching is defined and used to extract the growth rate from numerical simulations, which are compared with theory [Dodin et al., Phys. Rev. Lett. 110, 215006 (2013)]. In addition, the general theory of trapped particle instability in 1D is revisited and a more accurate description of the dispersion relation is obtained. Excellent agreement between numerical and theoretical predictions of growth rates of the bunching instability is shown over a range of parameters

  10. Quantitative study of the trapped particle bunching instability in Langmuir waves

    Energy Technology Data Exchange (ETDEWEB)

    Hara, Kentaro, E-mail: kenhara@umich.edu; Boyd, Iain D. [Department of Aerospace Engineering, University of Michigan, Ann Arbor, Michigan 48109 (United States); Chapman, Thomas; Joseph, Ilon; Berger, Richard L. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Banks, Jeffrey W. [Department of Mathematical Sciences, Rensselaer Polytechnic Institute, Troy, New York 12180 (United States); Brunner, Stephan [Centre de Recherches en Physique des Plasmas, Association Euratom-Confederation Suisse, Ecole Polytechnique Fédérale de Lausanne, CRPP-PPB, CH-1015 Lausanne (Switzerland)

    2015-02-15

    The bunching instability of particles trapped in Langmuir waves is studied using Vlasov simulations. A measure of particle bunching is defined and used to extract the growth rate from numerical simulations, which are compared with theory [Dodin et al., Phys. Rev. Lett. 110, 215006 (2013)]. In addition, the general theory of trapped particle instability in 1D is revisited and a more accurate description of the dispersion relation is obtained. Excellent agreement between numerical and theoretical predictions of growth rates of the bunching instability is shown over a range of parameters.

  11. Suppression of Longitudinal Coupled-Bunch Instabilities at the KEK-PF

    International Nuclear Information System (INIS)

    Obina, T.; Tobiyama, M.; Honda, T.; Tadano, M.; Flanagan, J.W.; Mitsuhashi, T.; Cheng, W.X.; Fox, J.D.; Teytelman, D.

    2012-01-01

    A bunch-by-bunch feedback system has been developed to suppress longitudinal coupled-bunch instabilities at the KEK-PF. A longitudinal kicker based on a DAFNE-type overdamped cavity has been designed and installed in the ring, and a general purpose signal processor, called iGp, has been developed by the collaboration of the KEK, SLAC, and INFN-LNF. The entire feedback loop has been closed by the end of June 2007, and the feedback system has successfully suppressed the longitudinal dipole-mode instabilities up to 430 mA.

  12. Shielded transient self-interaction of a bunch entering a circle from a straight path

    International Nuclear Information System (INIS)

    Li, R.; Bohn, C.L.; Bisognano, J.J.

    1997-01-01

    When a short (mm-length) bunch with high (nC-regime) charge is transported through a magnetic bending system, self-interaction via coherent synchrotron radiation (CSR) and space charge may alter the bunch dynamics significantly. The authors consider a Gaussian rigid-line-charge bunch following a straight-path trajectory into a circle, with the trajectory centered between two infinite, parallel, perfectly conducting plates. Transients associated with CSR and space charge generated from source particles both on the straight path and the circle are calculated, and their net effect on the radiated power is contrasted with that of shielded steady-state CSR

  13. Experiments on resonator concept of plasma wakefield accelerator driven by a train of relativistic electron bunches

    International Nuclear Information System (INIS)

    Kiselev, V.A.; Linnik, A.F.; Mirny, V. I; Onishchenko, I.N.; Uskov, V.V.

    2008-01-01

    The experimental installation was elaborated to increase plasma wakefield amplitude by means of using plasma resonator that allows all bunches of the train to participate in wakefield build-up contrary to waveguide case, in which due to group velocity effect only a part of the bunches participates. Experiments on plasma producing with resonant density, at which a coincidence of the plasma frequency and bunch repetition frequency is provided, are carried out. The first results of the measurements of beam energy loss on plasma wakefield excitation and energy gain by accelerated electrons are presented

  14. LHC-rate beam test of CMS pixel barrel modules

    International Nuclear Information System (INIS)

    Erdmann, W.; Hoermann, Ch.; Kotlinski, D.; Horisberger, R.; Kaestli, H. Chr.; Gabathuler, K.; Bertl, W.; Meier, B.; Langenegger, U.; Trueeb, P.; Rohe, T.

    2007-01-01

    Modules for the CMS pixel barrel detector have been operated in a high rate pion beam at PSI in order to verify under LHC-like conditions the final module design for the production. The test beam provided charged particle rates up to 10 8 cm -2 s -1 over the full module area. Bunch structure and randomized high trigger rates simulated realistic operation. A four layer telescope made of single pixel readout chip assemblies provided tracking needed for the determination of the modules hit reconstruction efficiency. The performance of the modules has been shown to be adequate for the CMS pixel barrel

  15. SU-F-T-202: An Evaluation Method of Lifetime Attributable Risk for Comparing Between Proton Beam Therapy and Intensity Modulated X-Ray Therapy for Pediatric Cancer Patients by Averaging Four Dose-Response Models for Carcinoma Induction

    Energy Technology Data Exchange (ETDEWEB)

    Tamura, M; Shirato, H [Department of Radiation Oncology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido (Japan); Ito, Y [Department of Biostatistics, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido (Japan); Sakurai, H; Mizumoto, M; Kamizawa, S [Proton Medical Research Center, University of Tsukuba, Tsukuba, Ibaraki (Japan); Murayama, S; Yamashita, H [Proton Therapy Division, Shizuoka Cancer Center Hospital, Nagaizumi, Shizuoka (Japan); Takao, S; Suzuki, R [Department of Medical Physics, Hokkaido University Hospital, Sapporo, Hokkaido (Japan)

    2016-06-15

    Purpose: To examine how much lifetime attributable risk (LAR) as an in silico surrogate marker of radiation-induced secondary cancer would be lowered by using proton beam therapy (PBT) in place of intensity modulated x-ray therapy (IMXT) in pediatric patients. Methods: From 242 pediatric patients with cancers who were treated with PBT, 26 patients were selected by random sampling after stratification into four categories: a) brain, head, and neck, b) thoracic, c) abdominal, and d) whole craniospinal (WCNS) irradiation. IMXT was re-planned using the same computed tomography and region of interest. Using dose volume histogram (DVH) of PBT and IMXT, the LAR of Schneider et al. was calculated for the same patient. The published four dose-response models for carcinoma induction: i) full model, ii) bell-shaped model, iii) plateau model, and ix) linear model were tested for organs at risk. In the case that more than one dose-response model was available, the LAR for this patient was calculated by averaging LAR for each dose-response model. Results: Calculation of the LARs of PBT and IMXT based on DVH was feasible for all patients. The mean±standard deviation of the cumulative LAR difference between PBT and IMXT for the four categories was a) 0.77±0.44% (n=7, p=0.0037), b) 23.1±17.2%,(n=8, p=0.0067), c) 16.4±19.8% (n=8, p=0.0525), and d) 49.9±21.2% (n=3, p=0.0275, one tailed t-test), respectively. The LAR was significantly lower by PBT than IMXT for the the brain, head, and neck region, thoracic region, and whole craniospinal irradiation. Conclusion: In pediatric patients who had undergone PBT, the LAR of PBT was significantly lower than the LAR of IMXT estimated by in silico modeling. This method was suggested to be useful as an in silico surrogate marker of secondary cancer induced by different radiotherapy techniques. This research was supported by the Translational Research Network Program, JSPS KAKENHI Grant No. 15H04768 and the Global Institution for

  16. SU-F-T-202: An Evaluation Method of Lifetime Attributable Risk for Comparing Between Proton Beam Therapy and Intensity Modulated X-Ray Therapy for Pediatric Cancer Patients by Averaging Four Dose-Response Models for Carcinoma Induction

    International Nuclear Information System (INIS)

    Tamura, M; Shirato, H; Ito, Y; Sakurai, H; Mizumoto, M; Kamizawa, S; Murayama, S; Yamashita, H; Takao, S; Suzuki, R

    2016-01-01

    Purpose: To examine how much lifetime attributable risk (LAR) as an in silico surrogate marker of radiation-induced secondary cancer would be lowered by using proton beam therapy (PBT) in place of intensity modulated x-ray therapy (IMXT) in pediatric patients. Methods: From 242 pediatric patients with cancers who were treated with PBT, 26 patients were selected by random sampling after stratification into four categories: a) brain, head, and neck, b) thoracic, c) abdominal, and d) whole craniospinal (WCNS) irradiation. IMXT was re-planned using the same computed tomography and region of interest. Using dose volume histogram (DVH) of PBT and IMXT, the LAR of Schneider et al. was calculated for the same patient. The published four dose-response models for carcinoma induction: i) full model, ii) bell-shaped model, iii) plateau model, and ix) linear model were tested for organs at risk. In the case that more than one dose-response model was available, the LAR for this patient was calculated by averaging LAR for each dose-response model. Results: Calculation of the LARs of PBT and IMXT based on DVH was feasible for all patients. The mean±standard deviation of the cumulative LAR difference between PBT and IMXT for the four categories was a) 0.77±0.44% (n=7, p=0.0037), b) 23.1±17.2%,(n=8, p=0.0067), c) 16.4±19.8% (n=8, p=0.0525), and d) 49.9±21.2% (n=3, p=0.0275, one tailed t-test), respectively. The LAR was significantly lower by PBT than IMXT for the the brain, head, and neck region, thoracic region, and whole craniospinal irradiation. Conclusion: In pediatric patients who had undergone PBT, the LAR of PBT was significantly lower than the LAR of IMXT estimated by in silico modeling. This method was suggested to be useful as an in silico surrogate marker of secondary cancer induced by different radiotherapy techniques. This research was supported by the Translational Research Network Program, JSPS KAKENHI Grant No. 15H04768 and the Global Institution for

  17. Femtosecond X-ray Pulses from a Spatially Chirped Electron Bunch in a SASE FEL

    Energy Technology Data Exchange (ETDEWEB)

    Emma, P.

    2003-01-14

    We propose a simple method to produce short x-ray pulses using a spatially chirped electron bunch in a SASE FEL. The spatial chirp is generated using an rf deflector which produces a transverse offset (in y and/or y') correlated with the longitudinal bunch position. Since the FEL gain is very sensitive to an initial offset in the transverse phase space at the entrance of the undulator, only a small portion of the electron bunch with relatively small transverse offset will interact significantly with the radiation, resulting in an x-ray pulse length much shorter than the electron bunch length. The x-ray pulse is also naturally phase locked to the rf deflector and so allows high precision timing synchronization. We discuss the generation and transport of such a spatially chirped electron beam and show that tens of femtosecond long pulse can be generated for the linac coherent light source (LCLS).

  18. 132 ns Bunch Spacing in the Tevatron Proton-Antiproton Collider

    International Nuclear Information System (INIS)

    Holmes, S.D.; Holt, J.; Johnstone, J.A.; Marriner, J.; Martens, M.; McGinnis, D.

    1994-12-01

    Following completion of the Fermilab Main Injector it is expected that the Tevatron proton-antiproton collider will be operating at a luminosity in excess of 5x10 3l cm -2 with 36 proton and antiproton bunches spaced at 396 nsec. At this luminosity, each of the experimental detectors will see approximately 1.3 interactions per crossing. Potential improvements to the collider low beta and rf systems could push the luminosity beyond 10x10 3l cm -2 sec -1 , resulting in more than three interactions per crossing if the bunch separation is left unchanged. This paper discusses issues related to moving to ∼100 bunch operation, with bunch spacings of 132 nsec, in the Tevatron. Specific scenarios and associated hardware requirements are described

  19. High-intensity coherent FIR radiation from sub-picosecond electron bunches

    International Nuclear Information System (INIS)

    Kung, P.H.; Lihn, Hung-chi; Wiedemann, H.; Bocek, D.

    1994-01-01

    A facility to generate high-intensity, ultra-short pulses of broad-band far-infrared radiation has been assembled and tested at Stanford. The device uses sub-picosecond relativistic electron bunches to generate coherent radiation through transition or synchrotron radiation in the far-infrared (FIR) regime between millimeter waves and wavelengths of about 100 μm and less. Experimental results show a peak radiation power of greater than 0.33 MW within a micro-bunch and an average FIR radiation power of 4 mW. The average bunch length of 2856 micro-bunches within a 1 μsec macro-pulse is estimated to be about 480 sec. Simulations experimental setup and results will be discussed

  20. Electron bunch structure in energy recovery linac with high-voltage dc photoelectron gun

    Directory of Open Access Journals (Sweden)

    Y. M. Saveliev

    2016-09-01

    Full Text Available The internal structure of electron bunches generated in an injector line with a dc photoelectron gun is investigated. Experiments were conducted on the ALICE (accelerators and lasers in combined experiments energy recovery linac at Daresbury Laboratory. At a relatively low dc gun voltage of 230 kV, the bunch normally consisted of two beamlets with different electron energies, as well as transverse and longitudinal characteristics. The beamlets are formed at the head and the tail of the bunch. At a higher gun voltage of 325 kV, the beam substructure is much less pronounced and could be observed only at nonoptimal injector settings. Experiments and computer simulations demonstrated that the bunch structure develops during the initial beam acceleration in the superconducting rf booster cavity and can be alleviated either by increasing the gun voltage to the highest possible level or by controlling the beam acceleration from the gun voltage in the first accelerating structure.