Geophysical techniques used in uranium exploration

International Nuclear Information System (INIS)

Meyer, P.A.

1977-01-01

The impetus in uranium exploration has been generated by the increase in price to about $40.00 a pound or $2.50 an ounce, a price that approaches a precious metal. Not only has the search increased in the traditional sandstone areas, but also in the igneous and metamorphic environments. Because uranium is one of the elements along with thorium and potassium that radiate alpha, beta and gamma rays; direct methods have been developed and improved upon to measure this radiation while indirect traditional geophysical methods have been used to assist in locating associated favorable structural and ''stratigraphic'' zones

Direct and indirect dating of gypsum occurrences in deserts using luminescence methods

International Nuclear Information System (INIS)

Nagar, Y.C.; Juyal, N.; Singhyi, A.K.; Kocurek, G.; Wadhawan, S.K.

2005-01-01

In the present study we have made an attempt to directly date gypsum or provide indirect age estimate for gypsum formation through dating the associated sediments (quartz) using the luminescence dating technique. In the direct dating of gypsum, we explored the Optically Stimulated Luminescence (OSL) and Thermally Stimulated Luminescence (TL) behaviour of gypsum. The associated sediments (indirect dating) were dated using the traces of quartz extract from gypsum (concentration 0.1% ) and the underlying and overlying quartz sand in playa

Ancestry of indirect techniques for X-ray imaging

International Nuclear Information System (INIS)

Mertz, L.

1989-01-01

Historical citations concerning the origins of coded-aperture imaging are corrected. Another scheme is presented for synthetic indirect imaging to overcome certain shortcomings of simple coded apertures. Pairs of Fresnel zone patterns are used to create moire patterns that can be Fourier transformed for image reconstruction. It is also conjectured that image reconstructions that are constrained to be nonnegative should overcome certain complaints concerning indirect imaging. 20 refs

Use of partial dissolution techniques in geochemical exploration

Science.gov (United States)

Chao, T.T.

1984-01-01

Application of partial dissolution techniques to geochemical exploration has advanced from an early empirical approach to an approach based on sound geochemical principles. This advance assures a prominent future position for the use of these techniques in geochemical exploration for concealed mineral deposits. Partial dissolution techniques are classified as single dissolution or sequential multiple dissolution depending on the number of steps taken in the procedure, or as "nonselective" extraction and as "selective" extraction in terms of the relative specificity of the extraction. The choice of dissolution techniques for use in geochemical exploration is dictated by the geology of the area, the type and degree of weathering, and the expected chemical forms of the ore and of the pathfinding elements. Case histories have illustrated many instances where partial dissolution techniques exhibit advantages over conventional methods of chemical analysis used in geochemical exploration. ?? 1984.

Network meta-analysis: a technique to gather evidence from direct and indirect comparisons

Science.gov (United States)

2017-01-01

Systematic reviews and pairwise meta-analyses of randomized controlled trials, at the intersection of clinical medicine, epidemiology and statistics, are positioned at the top of evidence-based practice hierarchy. These are important tools to base drugs approval, clinical protocols and guidelines formulation and for decision-making. However, this traditional technique only partially yield information that clinicians, patients and policy-makers need to make informed decisions, since it usually compares only two interventions at the time. In the market, regardless the clinical condition under evaluation, usually many interventions are available and few of them have been studied in head-to-head studies. This scenario precludes conclusions to be drawn from comparisons of all interventions profile (e.g. efficacy and safety). The recent development and introduction of a new technique – usually referred as network meta-analysis, indirect meta-analysis, multiple or mixed treatment comparisons – has allowed the estimation of metrics for all possible comparisons in the same model, simultaneously gathering direct and indirect evidence. Over the last years this statistical tool has matured as technique with models available for all types of raw data, producing different pooled effect measures, using both Frequentist and Bayesian frameworks, with different software packages. However, the conduction, report and interpretation of network meta-analysis still poses multiple challenges that should be carefully considered, especially because this technique inherits all assumptions from pairwise meta-analysis but with increased complexity. Thus, we aim to provide a basic explanation of network meta-analysis conduction, highlighting its risks and benefits for evidence-based practice, including information on statistical methods evolution, assumptions and steps for performing the analysis. PMID:28503228

′An avant-garde indirect bonding technique for lingual orthodontics using the first complete digital "tad" (torque angulation device, & "BPD" (bracket positioning device′

Directory of Open Access Journals (Sweden)

Tushar Hegde

2010-01-01

This article covers an Indirect Bonding Technique using the Torque Angulation Device (TAD and the Bracket Positioning Device (BPD which ensure great accuracy while minimizing the poten- tial for error as compared to most methods available to the orthodontist today. This technique has been developed by taking into account the advantages and pitfalls of indirect bonding.

Exploring direct and indirect influences of physical work environment on job satisfaction for early-career registered nurses employed in hospitals.

Science.gov (United States)

Djukic, Maja; Kovner, Christine T; Brewer, Carol S; Fatehi, Farida; Greene, William H

2014-08-01

We explored direct and indirect influences of physical work environment on job satisfaction in a nationally representative sample of 1,141 early-career registered nurses. In the fully specified model, physical work environment had a non-significant direct effect on job satisfaction. The path analysis used to test multiple indirect effects showed that physical work environment had a positive indirect effect (p nurse-physician relations, quantitative workload, organizational constraints, distributive justice, promotional opportunity, local and non-local job opportunities. The findings make important contributions to the understanding of the relationship between physical work environment and job satisfaction. The results can inform health care leaders' insight about how physical work environment influences nurses' job satisfaction. © 2014 Wiley Periodicals, Inc.

The effect of feeding on CO2 production and energy expenditure in ponies measured by indirect calorimetry and the 13C-bicarbonate technique

DEFF Research Database (Denmark)

Jensen, Rasmus Bovbjerg; Kyrstein, T. D.; Junghans, P

2015-01-01

Energy expenditure (EE) can be estimated based on respiratory gas exchange measurements, traditionally done in respiration chambers by indirect calorimetry (IC). However, the (13)C-bicarbonate technique ((13)C-BT) might be an alternative minimal invasive method for estimation of CO(2) production...... and EE in the field. In this study, four Shetland ponies were used to explore the effect of feeding on CO(2) production and EE measured simultaneously by IC and (13)C-BT. The ponies were individually housed in respiration chambers and received either a single oral or intravenous (IV) bolus dose of (13)C......-bicarbonate at the three different feeding times. Feeding time affected the CO(2) production (P

Special aspects of the indirect radiotracer technique when used to study the adsorption and electrochemical reactions of organic substances at solid electrodes

International Nuclear Information System (INIS)

Andreev, V.N.; Horanyi, G.; Kazarinov, V.E.

1986-01-01

This paper analyzes the possibilities and special aspects of the indirect radiotracer technique with a number of examples. Data are presented concerning the effects of acetic and oxalic acid on chloride ion adsorption on platinized platinum electrodes at a potential E = 0.2 V. The effect on chloride ion adsorption is much larger in the case of oxalic acid, which is evidence for its higher adsorbability on platinum at E = 0.2 V. It is shown that the indirect radiotracer technique offers significant possibilities for studying the electrochemical properties of adsorption products of organic substances

Exploring untrained interpreters' use of direct versus indirect speech

DEFF Research Database (Denmark)

Dubslaff, Friedel; Martinsen, Bodil

2005-01-01

by personalizing the indefinite pronoun 'one' when relaying from doctor to patient. All other pronoun shifts occurred in connection with interactional problems caused almost exclusively by the interpreters' lack of knowledge about medical terminology - even though the terms used were in fact non-specialized ones....... The study also indicates that primary parties' shifts from direct to indirect address are closely related either to the form or to the content of the interpreter's prior utterance. Finally, it emerges that repeated one-language talk, triggered by the interpreter's problems with medical terminology, can......This study examines the interrelations between the use of direct vs. indirect speech by primary participants and by dialogue interpreters by focusing on pronoun shifts and their interactional functions. The data consist of four simulated interpreter-mediated medical interviews based on the same...

RADIOMETRIC TECHNIQUES IN HEAVY MINERAL EXPLORATION AND EXPLOITATION

NARCIS (Netherlands)

DEMEIJER, RJ; TANCZOS, IC; STAPEL, C

1994-01-01

In recent years the Environmental Research Group of the KVI has been developing a number of radiometric techniques that may be employed in mineral sand exploration. These techniques involve: radiometric fingerprinting for assessing sand provenances and mineralogical composition; thermoluminescence

Wide-band analog frequency modulation of optic signals using indirect techniques

Science.gov (United States)

Fitzmartin, D. J.; Balboni, E. J.; Gels, R. G.

1991-01-01

The wideband frequency modulation (FM) of an optical carrier by a radio frequency (RF) or microwave signal can be accomplished independent of laser type when indirect modulation is employed. Indirect modulators exploit the integral relation of phase to frequency so that phase modulators can be used to impress frequency modulation on an optical carrier. The use of integrated optics phase modulators, which are highly linear, enables the generation of optical wideband FM signals with very low intermodulation distortion. This modulator can be used as part of an optical wideband FM link for RF and microwave signals. Experimental results from the test of an indirect frequency modulator for an optical carrier are discussed.

Pedal indirect lymphangiography

International Nuclear Information System (INIS)

Lee, Kil Woo; Hong, Myung Sun; Kim, In Jae

1994-01-01

Recently, indirect lymphangiography has been developed as a relatively good and noninvasive imaging modality of the lymphatic system at extremities. But the disadvantage of the indirect lymphangiography is a low contrast ratio between the surrounding tissues and the contrast media in lymphatic vessels, because dimeric nonionic contrast media is water soluble and diluted in the proximal leg lymphatic vessels. We could have relatively better image than previously published images for the leg lymphatic system, when we injected contrast media with adequate high pressure in intradermal space of the interdigital areas at the foot dorsum. So, we would like to report the results. We could study all 9 lymphedemas(primary: 6, secondary: 3) from April 1990 to May 1993 on outpatient base. They were diagnosed as lymphedema clinically and radiologically. Ten ml of dimeric nonionic aget, iotrolan(Isovist 300) was injected into intradermal space with five 30-gauge needles. The injection speed was more than 0.2 ml/min. We have done one side pedal lymphangiogram in 30 minutes. The evaluation of the anterior superficial lymphatics was according to the criteria of the Weissleder. The results were as follows: 1. All lymphatic vessels from foot to inguinal area could be visualized. 2. Two or three inferior inguinal lymph nodes could be visualized about 42%. 3. The most common abnormal finding of the lymphedma was the neovascularization of the lymphatics on indirect pedal lymphangiogram. If we use adequate technique relatively high pressure injection, correct intradermal needle insertion, adequate soft tissue exposure technique indirect lymphangiography is considered to be a safe and noninvasive imaging modality for the evaluation of the lymphedema of lower extremity lymphatics including inferior inguinal lymph nodes

Indirect Self-Destructiveness and Emotional Intelligence.

Science.gov (United States)

Tsirigotis, Konstantinos

2016-06-01

While emotional intelligence may have a favourable influence on the life and psychological and social functioning of the individual, indirect self-destructiveness exerts a rather negative influence. The aim of this study has been to explore possible relations between indirect self-destructiveness and emotional intelligence. A population of 260 individuals (130 females and 130 males) aged 20-30 (mean age of 24.5) was studied by using the Polish version of the chronic self-destructiveness scale and INTE, i.e., the Polish version of the assessing emotions scale. Indirect self-destructiveness has significant correlations with all variables of INTE (overall score, factor I, factor II), and these correlations are negative. The intensity of indirect self-destructiveness differentiates significantly the height of the emotional intelligence and vice versa: the height of the emotional intelligence differentiates significantly the intensity of indirect self-destructiveness. Indirect self-destructiveness has negative correlations with emotional intelligence as well as its components: the ability to recognize emotions and the ability to utilize emotions. The height of emotional intelligence differentiates the intensity of indirect self-destructiveness, and vice versa: the intensity of indirect self-destructiveness differentiates the height of emotional intelligence. It seems advisable to use emotional intelligence in the prophylactic and therapeutic work with persons with various types of disorders, especially with the syndrome of indirect self-destructiveness.

Calibrated delivery drape versus indirect gravimetric technique for the measurement of blood loss after delivery: a randomized trial.

Science.gov (United States)

Ambardekar, Shubha; Shochet, Tara; Bracken, Hillary; Coyaji, Kurus; Winikoff, Beverly

2014-08-15

Trials of interventions for PPH prevention and treatment rely on different measurement methods for the quantification of blood loss and identification of PPH. This study's objective was to compare measures of blood loss obtained from two different measurement protocols frequently used in studies. Nine hundred women presenting for vaginal delivery were randomized to a direct method (a calibrated delivery drape) or an indirect method (a shallow bedpan placed below the buttocks and weighing the collected blood and blood-soaked gauze/pads). Blood loss was measured from immediately after delivery for at least one hour or until active bleeding stopped. Significantly greater mean blood loss was recorded by the direct than by the indirect measurement technique (253.9 mL and 195.3 mL, respectively; difference = 58.6 mL (95% CI: 31-86); p 500 mL (8.7% vs. 4.7%, p = 0.02). The study suggests a real and significant difference in blood loss measurement between these methods. Research using blood loss measurement as an endpoint needs to be interpreted taking measurement technique into consideration. This study has been registered at clinicaltrials.gov as NCT01885845.

Comparative study on direct and indirect bracket bonding techniques regarding time length and bracket detachment

Directory of Open Access Journals (Sweden)

Jefferson Vinicius Bozelli

2013-12-01

Full Text Available OBJECTIVE: The aim of this study was to assess the time spent for direct (DBB - direct bracket bonding and indirect (IBB - indirect bracket bonding bracket bonding techniques. The time length of laboratorial (IBB and clinical steps (DBB and IBB as well as the prevalence of loose bracket after a 24-week follow-up were evaluated. METHODS: Seventeen patients (7 men and 10 women with a mean age of 21 years, requiring orthodontic treatment were selected for this study. A total of 304 brackets were used (151 DBB and 153 IBB. The same bracket type and bonding material were used in both groups. Data were submitted to statistical analysis by Wilcoxon non-parametric test at 5% level of significance. RESULTS: Considering the total time length, the IBB technique was more time-consuming than the DBB (p < 0.001. However, considering only the clinical phase, the IBB took less time than the DBB (p < 0.001. There was no significant difference (p = 0.910 for the time spent during laboratorial positioning of the brackets and clinical session for IBB in comparison to the clinical procedure for DBB. Additionally, no difference was found as for the prevalence of loose bracket between both groups. CONCLUSION: the IBB can be suggested as a valid clinical procedure since the clinical session was faster and the total time spent for laboratorial positioning of the brackets and clinical procedure was similar to that of DBB. In addition, both approaches resulted in similar frequency of loose bracket.

New developments in the techniques of uranium exploration in Egypt. Case histories for exploration under arid conditions

International Nuclear Information System (INIS)

El-Shazly, E.M.; Meshref, W.M.; Ammar, A.A.; El-Ghawaby, M.A.; El-Kassas, I.A.; El-Rakaiby, M.M.

1977-01-01

Exploration for radioactive mineralizations and mineral accumulations in Egypt during the last five years involved the application of new techniques and their adaptation to the prevailing semi-arid to arid environment. The mobilization of uranium and thorium, and their daughter products in the oxidation zone, is greatly influenced by this particular environment. Exploration techniques employed include the use of airborne, space-borne, ground and sub-surface methodologies. Case histories for uranium exploration have been formulated through practical experience, which can be applied in the arid regions in different parts of the world where conditions are comparable to those of Egypt. (author)

Indirect methods for reference interval determination - review and recommendations.

Science.gov (United States)

Jones, Graham R D; Haeckel, Rainer; Loh, Tze Ping; Sikaris, Ken; Streichert, Thomas; Katayev, Alex; Barth, Julian H; Ozarda, Yesim

2018-04-19

Reference intervals are a vital part of the information supplied by clinical laboratories to support interpretation of numerical pathology results such as are produced in clinical chemistry and hematology laboratories. The traditional method for establishing reference intervals, known as the direct approach, is based on collecting samples from members of a preselected reference population, making the measurements and then determining the intervals. An alternative approach is to perform analysis of results generated as part of routine pathology testing and using appropriate statistical techniques to determine reference intervals. This is known as the indirect approach. This paper from a working group of the International Federation of Clinical Chemistry (IFCC) Committee on Reference Intervals and Decision Limits (C-RIDL) aims to summarize current thinking on indirect approaches to reference intervals. The indirect approach has some major potential advantages compared with direct methods. The processes are faster, cheaper and do not involve patient inconvenience, discomfort or the risks associated with generating new patient health information. Indirect methods also use the same preanalytical and analytical techniques used for patient management and can provide very large numbers for assessment. Limitations to the indirect methods include possible effects of diseased subpopulations on the derived interval. The IFCC C-RIDL aims to encourage the use of indirect methods to establish and verify reference intervals, to promote publication of such intervals with clear explanation of the process used and also to support the development of improved statistical techniques for these studies.

Geophysical and geochemical techniques for exploration of hydrocarbons and minerals

International Nuclear Information System (INIS)

Sittig, M.

1980-01-01

The detailed descriptive information in this book is based on 389 US patents that deal with geophysical and geochemical techniques useful for the exploration of hydrocarbons and minerals. Where it was necessary to round out the complete technological picture, a few paragraphs from cited government reports have been included. These techniques are used in prospecting for oil, coal, oil shale, tar sand and minerals. The patents are grouped under the following chapters: geochemical prospecting; geobiological prospecting; geophysical exploration; magnetic geophysical prospecting; gravitational geophysical prospecting; electrical geophysical prospecting; nuclear geophysical prospecting; seismic geophysical prospecting; and exploratory well drilling. This book serves a double purpose in that it supplies detailed technical information and can be used as a guide to the US patent literature in this field. By indicating all the information that is significant, and eliminating legal jargon and juristic phraseology, this book presents an advanced, industrially oriented review of modern methods of geophysical and geochemical exploration techniques

Forecasting of indirect consumables for a Job Shop

Science.gov (United States)

Shakeel, M.; Khan, S.; Khan, W. A.

2016-08-01

A job shop has an arrangement where similar machines (Direct consumables) are grouped together and use indirect consumables to produce a product. The indirect consumables include hack saw blades, emery paper, painting brush etc. The job shop is serving various orders at a particular time for the optimal operation of job shop. Forecasting is required to predict the demand of direct and indirect consumables in a job shop. Forecasting is also needed to manage lead time, optimize inventory cost and stock outs. The objective of this research is to obtain the forecast for indirect consumables. The paper shows how job shop can manage their indirect consumables more accurately by establishing a new technique of forecasting. This results in profitable use of job shop by multiple users.

Exploration of projective techniques to unravel health perception

NARCIS (Netherlands)

Sijtsema, S.J.; Linnemann, A.R.; Backus, G.B.C.; Jongen, W.M.F.; Gaasbeek, van A.F.; Dagevos, H.

2007-01-01

Purpose - This paper seeks to explore the design, organisation and application of group discussions in which projective techniques (expressive and associative) are used to unravel health perception of consumers in cognitive and affective terms. Design/methodology/approach - A trained moderator led

Learning and transfer of category knowledge in an indirect categorization task.

Science.gov (United States)

Helie, Sebastien; Ashby, F Gregory

2012-05-01

Knowledge representations acquired during category learning experiments are 'tuned' to the task goal. A useful paradigm to study category representations is indirect category learning. In the present article, we propose a new indirect categorization task called the "same"-"different" categorization task. The same-different categorization task is a regular same-different task, but the question asked to the participants is about the stimulus category membership instead of stimulus identity. Experiment 1 explores the possibility of indirectly learning rule-based and information-integration category structures using the new paradigm. The results suggest that there is little learning about the category structures resulting from an indirect categorization task unless the categories can be separated by a one-dimensional rule. Experiment 2 explores whether a category representation learned indirectly can be used in a direct classification task (and vice versa). The results suggest that previous categorical knowledge acquired during a direct classification task can be expressed in the same-different categorization task only when the categories can be separated by a rule that is easily verbalized. Implications of these results for categorization research are discussed.

CT-guided cervical nerve root injections: comparing the immediate post-injection anesthetic-related effects of the transforaminal injection with a new indirect technique

International Nuclear Information System (INIS)

Sutter, Reto; Pfirrmann, Christian W.A.; Peterson, Cynthia K.; Zanetti, Marco; Hodler, Juerg

2011-01-01

To describe an ''indirect'' cervical nerve root injection technique with a dorsal approach that should carry less inherent risk than the ''direct'' cervical transforaminal injection approach, and to compare the immediate post-injection results of the two procedures. The indirect and direct cervical nerve root injection procedures are described in detail. Fifty-three consecutive patients receiving the indirect nerve root injections during 2009-2010 were age- and gender-matched to 53 patients who underwent direct transforaminal nerve root injections performed in 2006. Pain level data were collected immediately before and 20-30 min after each procedure. The percentages of pain change in the two groups were compared using the unpaired Student's t test. Fifty-two men (mean age 49) and 54 women (mean age 55) were included. The mean percentage of pain reduction for patients receiving indirect nerve root injections was 38.4% and for those undergoing the direct nerve root injections approach it was 43.2%. This was not significantly different (P = 0.455). No immediate or late adverse effects were reported after either injection procedure. The indirect cervical nerve root injection procedure is a potentially safer alternative to direct cervical transforaminal nerve root injections. The short-term pain reduction is similar using the two injection methods. (orig.)

Indirect reciprocity with optional interactions.

Science.gov (United States)

Ghang, Whan; Nowak, Martin A

2015-01-21

Indirect reciprocity is a mechanism for the evolution of cooperation that is relevant for prosocial behavior among humans. Indirect reciprocity means that my behavior towards you also depends on what you have done to others. Indirect reciprocity is associated with the evolution of social intelligence and human language. Most approaches to indirect reciprocity assume obligatory interactions, but here we explore optional interactions. In any one round a game between two players is offered. A cooperator accepts a game unless the reputation of the other player indicates a defector. For a game to take place, both players must accept. In a game between a cooperator and a defector, the reputation of the defector is revealed to all players with probability Q. After a sufficiently large number of rounds the identity of all defectors is known and cooperators are no longer exploited. The crucial condition for evolution of cooperation can be written as hQB>1, where h is the average number of rounds per person and B=(b/c)-1 specifies the benefit-to-cost ratio. We analyze both stochastic and deterministic evolutionary game dynamics. We study two extensions that deal with uncertainty: hesitation and malicious gossip. Copyright © 2014 Elsevier Ltd. All rights reserved.

Exploring Traditional Glass Bead Making Techniques in Jewellery ...

African Journals Online (AJOL)

Exploring traditional glass bead making techniques in jewellery in some prominent areas in Ghana is a means to exposing the area for metal and ceramic artists and other related fields of discipline such as aesthetics and criticism to complement their form of ... Keywords: livelihood, vitreous, glass bottles, furnace, threading ...

Uranium exploration and evaluation techniques

International Nuclear Information System (INIS)

Bowie, S.H.U.

1977-01-01

Ground, carborne and airborne surveys for uranium commenced with GM-counters and developed to total-count scintillation counters which have subsequently been replaced to some extent by gamma spectrometers. Stabilisation of the last mentioned is important and has only been achieved recently. Hydrogeochemistry has been revitalised by the introduction of neutron activation analysis and has considerable promise of success in the discovery of surface and near-surface uranium deposits. Soil, stream sediment and lake sediment analyses also have potential particularly in follow-up surveys. One of the most encouraging methods of detecting relatively deeply buried uranium ore bodies is by measuring the radon content of air retained in soil or sub-soil; also that dissolved in stream or lake water. Helium, particularly 4 He, which is also a decay product of uranium but which has an infinite half-life could be measured along with radon. Theoretically this could not only give additional information on buried ore bodies, but on the depth of burial. Another possible technique for use in the detection of buried ore bodies is that of measuring the increased heat flow at surface which, in favourable circumstatnces, should be associated with significant uranium occurrences. Measurement of heat flow could either be by surface thermal sensors or by thermal infra-red scanning techniques from aircraft. For the purposes of preliminary surveys of large areas, airborne geochemical techniques offer considerable scope. Possibilities include the measurement of 222 Rn in the atmosphere. Alternatively, one or more of the decay products of radon could be measured. These are 210 Pb, 210 Bi and 210 Po. It is concluded that there is ample evidence to suggest that the more widespread application of known exploration methods, together with new techniques that can already be envisaged, will result in important new discoveries of uranium reserves

Indirect effects in community ecology: Their definition, study and importance.

Science.gov (United States)

Strauss, S Y

1991-07-01

The diversity of indirect interactions that can occur within communities is large. Recent research on indirect interactions is scattered in the literature under numerous labels. The definition of indirect effects is an important aspect of their study, and clarifies some of the subtle differences among indirect effects found in natural communities. Choosing which species to study, how to manipulate species and for what duration, which attributes to measure and, finally, which analytical techniques to use are all problems facing the community ecologist. Ultimately, we are striving for the best means of determining the relative importance of direct and indirect effects in structuring communities. Copyright © 1991. Published by Elsevier Ltd.

Nuclear techniques in marine metal exploration

International Nuclear Information System (INIS)

Michaelis, W.

1979-01-01

The growing concern about the future availability of raw materials has increasingly drawn attention to the extensive marine metalliferous mineral deposits. Nuclear techniques can provide powerful analytical tools for exploring these resources. The measurement of natural gamma radiation, X-ray fluorescence analysis and a variety of neutron techniques based on 252 Cf, (α,n) and (d,n) sources are now in use or appear to make progress. Improvement of the relevant cross sections could considerably advance the technical development both in the field and in the laboratory. Particular consideration should be given to a number of energy-dependent cross sections pertaining to neutron and gamma transport in field application of activation analysis or radiative capture, to neutron cross sections for production of gamma rays from inelastic collisions, to cross sections of threshold reactions which either ensure elemental selectivity or are the source of elemental interferences and, finally, to cross sections for quasi-prompt activation with 14 MeV neutrons. (orig.) [de

A reflexive exploration of two qualitative data coding techniques

Directory of Open Access Journals (Sweden)

Erik Blair

2016-01-01

Full Text Available In an attempt to help find meaning within qualitative data, researchers commonly start by coding their data. There are a number of coding systems available to researchers and this reflexive account explores my reflections on the use of two such techniques. As part of a larger investigation, two pilot studies were undertaken as a means to examine the relative merits of open coding and template coding for examining transcripts. This article does not describe the research project per se but attempts to step back and offer a reflexive account of the development of data coding tools. Here I reflect upon and evaluate the two data coding techniques that were piloted, and discuss how using appropriate aspects of both led to the development of my final data coding approach. My exploration found there was no clear-cut ‘best’ option but that the data coding techniques needed to be reflexively-aligned to meet the specific needs of my project. This reflection suggests that, when coding qualitative data, researchers should be methodologically thoughtful when they attempt to apply any data coding technique; that they do not assume pre-established tools are aligned to their particular paradigm; and that they consider combining and refining established techniques as a means to define their own specific codes. DOI: 10.2458/azu_jmmss.v6i1.18772DOI: 10.2458/azu_jmmss.v6i1.18772

A new method of fabricating a blend scaffold using an indirect three-dimensional printing technique

International Nuclear Information System (INIS)

Jung, Jin Woo; Lee, Hyungseok; Hong, Jung Min; Park, Jeong Hun; Cho, Dong-Woo; Shim, Jung Hee; Choi, Tae Hyun

2015-01-01

Due to its simplicity and effectiveness, the physical blending of polymers is considered to be a practical strategy for developing a versatile scaffold having desirable mechanical and biochemical properties. In the present work, an indirect three-dimensional (i3D) printing technique was proposed to fabricate a 3D free-form scaffold using a blend of immiscible materials, such as polycaprolactone (PCL) and gelatin. The i3D printing technique includes 3D printing of a mold and a sacrificial molding process. PCL/chloroform and gelatin/water were physically mixed to prepare the blend solution, which was subsequently injected into the cavity of a 3D printed mold. After solvent removal and gelatin cross-linking, the mold was dissolved to obtain a PCL–gelatin (PG) scaffold, with a specific 3D structure. Scanning electron microscopy and Fourier transform infrared spectroscopy analysis indicated that PCL masses and gelatin fibers in the PG scaffold homogenously coexisted without chemical bonding. Compression tests confirmed that gelatin incorporation into the PCL enhanced its mechanical flexibility and softness, to the point of being suitable for soft-tissue engineering, as opposed to pure PCL. Human adipose-derived stem cells, cultured on a PG scaffold, exhibited enhanced in vitro chondrogenic differentiation and tissue formation, compared with those on a PCL scaffold. The i3D printing technique can be used to blend a variety of materials, facilitating 3D scaffold fabrication for specific tissue regeneration. Furthermore, this convenient and versatile technique may lead to wider application of 3D printing in tissue engineering. (paper)

A new method of fabricating a blend scaffold using an indirect three-dimensional printing technique.

Science.gov (United States)

Jung, Jin Woo; Lee, Hyungseok; Hong, Jung Min; Park, Jeong Hun; Shim, Jung Hee; Choi, Tae Hyun; Cho, Dong-Woo

2015-11-03

Due to its simplicity and effectiveness, the physical blending of polymers is considered to be a practical strategy for developing a versatile scaffold having desirable mechanical and biochemical properties. In the present work, an indirect three-dimensional (i3D) printing technique was proposed to fabricate a 3D free-form scaffold using a blend of immiscible materials, such as polycaprolactone (PCL) and gelatin. The i3D printing technique includes 3D printing of a mold and a sacrificial molding process. PCL/chloroform and gelatin/water were physically mixed to prepare the blend solution, which was subsequently injected into the cavity of a 3D printed mold. After solvent removal and gelatin cross-linking, the mold was dissolved to obtain a PCL-gelatin (PG) scaffold, with a specific 3D structure. Scanning electron microscopy and Fourier transform infrared spectroscopy analysis indicated that PCL masses and gelatin fibers in the PG scaffold homogenously coexisted without chemical bonding. Compression tests confirmed that gelatin incorporation into the PCL enhanced its mechanical flexibility and softness, to the point of being suitable for soft-tissue engineering, as opposed to pure PCL. Human adipose-derived stem cells, cultured on a PG scaffold, exhibited enhanced in vitro chondrogenic differentiation and tissue formation, compared with those on a PCL scaffold. The i3D printing technique can be used to blend a variety of materials, facilitating 3D scaffold fabrication for specific tissue regeneration. Furthermore, this convenient and versatile technique may lead to wider application of 3D printing in tissue engineering.

Tapping into Recovery: Exploring Experiences of Emotional Freedom Techniques (EFT)

OpenAIRE

MAHIMA KALLA

2018-01-01

This thesis explores users' experiences of utilising a contemporary therapeutic intervention, called Emotional Freedom Techniques (EFT) for supporting physical chronic disease healthcare. Eight chronic disease patients and eight EFT practitioners were interviewed for this study. An in-depth exploration of the sixteen participants' experiences of using EFT to support chronic disease healthcare was undertaken using a qualitative research methodology. Findings of this study suggest that chronic ...

A Novel Sliding Mode Control Technique for Indirect Current Controlled Active Power Filter

Directory of Open Access Journals (Sweden)

Juntao Fei

2012-01-01

Full Text Available A novel sliding mode control (SMC method for indirect current controlled three-phase parallel active power filter is presented in this paper. There are two designed closed loops in the system: one is the DC voltage controlling loop and the other is the reference current tracking loop. The first loop with a PI regulator is used to control the DC voltage approximating to the given voltage of capacitor, and the output of PI regulator through a low-pass filter is applied as the input of the power supply reference currents. The second loop implements the tracking of the reference currents using integral sliding mode controller, which can improve the harmonic treating performance. Compared with the direct current control technique, it is convenient to be implemented with digital signal processing system because of simpler system structure and better harmonic treating property. Simulation results verify that the generated reference currents have the same amplitude with the load currents, demonstrating the superior harmonic compensating effects with the proposed shunt active power filter compared with the hysteresis method.

Indirect Determination of the sigma - omega

DEFF Research Database (Denmark)

Ulfkjær, J. P.; Brincker, Rune

. The beams where submitted to three-point bending in a servo-controlled materials testing system. The constitutive parameters in the fictitious crack model were determined by using three different indirect techniques, which are described and evaluated. The results show that the fracture energy is increasing...

Effectiveness of direct and indirect radionuclide cystography in detecting vesicoureteral reflux

International Nuclear Information System (INIS)

Conway, J.J.; Kruglik, G.D.

1976-01-01

A modified of the direct radionuclide cystography technique to include filling, voiding, and postvoiding phases of the examination permitted a simulated comparison between direct and indirect radionuclide cystography. One hundred thirty-seven examples of reflux were documented with this technique. Of these, 96 instances of reflux (70 percent) were recorded during two or more phases and thus would have been detected by either technique. Twenty-nine examples (21 percent) were only detected during filling and thus would have been missed by the indirect radionuclide technique and by some roentgenographic techniques. Only 12 examples (9 percent) were detected during the voiding phase only. The modified direct method of radionuclide cystography, which continuously monitors the urinary tracts during filling, voiding, and postvoiding, is offered as the best current technique for assessing visicoureteral reflus

Novel geochemical techniques integrated in exploration for uranium deposits at depth

International Nuclear Information System (INIS)

Kyser, K.

2014-01-01

Mineral deposits are in fact geochemical anomalies, and as such their detection and assessment of their impact on the environment should be facilitated using geochemical techniques. Although geochemistry has been used directly in the discovery of uranium deposits and more indirectly in shaping deposit models, the novel applications of geochemistry and integration with other data can be more effective in formulating exploration and remediation strategies. Recent research on the use of geochemistry in detecting uranium deposits at depth include: (1) more effective integration of geochemical with geophysical data to refine targets, (2) revealing element distributions in and around deposits to adequately assess the total chemical environment associated with the deposit, (3) the use of element tracing using elemental concentrations and isotopic compositions in the near surface environment to detect specific components that have migrated to the surface from uranium deposits at depth, (4) understand the effects of both macro- and micro-environments on element mobility across the geosphere-biosphere interface to enhance exploration using select media for uranium at depth. Geophysical data used in exploration can identify areas of conductors where redox contrasts may host mineralization, structures that act to focus fluids during formation of the deposits and act as conduits for element migration to the surface, and contrasts in geology that are required for the deposits. However, precision of these data is greatly diminished with depth, but geochemical data from drill core or surface media can enhance target identification when integrated with geophysical data. Geochemical orientation surveys over known unconformity-related deposits at depth clearly identify mineralization 900m deep. Drill core near the deposit, clay-size fractions separated from soil horizons and vegetation over and far from the deposit record element migration from the deposit as radiogenic He, Rn and Pb

Development of a New Technique to Assess Susceptibility to Predation Resulting from Sublethal Stresses (Indirect Mortality)

Energy Technology Data Exchange (ETDEWEB)

Cada, G.F.

2003-08-25

Fish that pass through a hydroelectric turbine may not be killed directly, but may nonetheless experience sublethal stresses that will increase their susceptibility to predators (indirect mortality). There is a need to develop reliable tests for indirect mortality so that the full consequences of passage through turbines (and other routes around a hydroelectric dam) can be assessed. We evaluated a new technique for assessing indirect mortality, based on a behavioral response to a startling stimulus (akin to perceiving an approaching predator). We compare this technique to the standard predator preference test. The behavioral response is a rapid movement commonly referred to as a startle response, escape response, or C-shape, based on the characteristic body position assumed by the fish. When viewed from above, a startled fish bends into a C-shape, then springs back and swims away in a direction different from its original orientation. This predator avoidance (escape) behavior can be compromised by sublethal stresses that temporarily stun or disorient the fish. We subjected striped shiners and fathead minnows to varying intensities of either turbulence (10-, 20- or 30-min) or 2-min exposures to a fish anesthetic (100 or 200 mg/L of tricaine methanesulfonate), and evaluated their subsequent behavior. Individual fish were given a startle stimulus and filmed with a high-speed video camera. Each fish was startled and filmed twice before being stressed, and then at 1-, 5-, 15-, and 30-min post-exposure. The resulting image files were analyzed for a variety of behavioral measures including: presence of a response, time to first reaction, duration of reaction, time to formation of maximum C-shape, time to completion of C-shape, and completeness of C-shape. The most immediate measure of potential changes in fish behavior was whether stressed fish exhibited a startle response. For striped shiners, the number of fish not responding to the stimulus was significantly different

Optical micromanipulation of active cells with minimal perturbations: direct and indirect pushing.

Science.gov (United States)

Wang, Chenlu; Chowdhury, Sagar; Gupta, Satyandra K; Losert, Wolfgang

2013-04-01

The challenge to wide application of optical tweezers in biological micromanipulation is the photodamage caused by high-intensity laser exposure to the manipulated living systems. While direct exposure to infrared lasers is less likely to kill cells, it can affect cell behavior and signaling. Pushing cells with optically trapped objects has been introduced as a less invasive alternative, but the technique includes some exposure of the biological object to parts of the optical tweezer beam. To keep the cells farther away from the laser, we introduce an indirect pushing-based technique for noninvasive manipulation of sensitive cells. We compare how cells respond to three manipulation approaches: direct manipulation, pushing, and indirect pushing. We find that indirect manipulation techniques lessen the impact of manipulation on cell behavior. Cell survival increases, as does the ability of cells to maintain shape and wiggle. Our experiments also demonstrate that indirect pushing allows cell-cell contacts to be formed in a controllable way, while retaining the ability of cells to change shape and move.

Exploration of Energy Metabolism in the Mouse Using Indirect Calorimetry: Measurement of Daily Energy Expenditure (DEE) and Basal Metabolic Rate (BMR).

Science.gov (United States)

Meyer, Carola W; Reitmeir, Peter; Tschöp, Matthias H

2015-09-01

Current comprehensive mouse metabolic phenotyping involves studying energy balance in cohorts of mice via indirect calorimetry, which determines heat release from changes in respiratory air composition. Here, we describe the measurement of daily energy expenditure (DEE) and basal metabolic rate (BMR) in mice. These well-defined metabolic descriptors serve as meaningful first-line read-outs for metabolic phenotyping and should be reported when exploring energy expenditure in mice. For further guidance, the issue of appropriate sample sizes and the frequency of sampling of metabolic measurements is also discussed. Copyright © 2015 John Wiley & Sons, Inc.

Indirect methods for wake potential integration

International Nuclear Information System (INIS)

Zagorodnov, I.

2006-05-01

The development of the modern accelerator and free-electron laser projects requires to consider wake fields of very short bunches in arbitrary three dimensional structures. To obtain the wake numerically by direct integration is difficult, since it takes a long time for the scattered fields to catch up to the bunch. On the other hand no general algorithm for indirect wake field integration is available in the literature so far. In this paper we review the know indirect methods to compute wake potentials in rotationally symmetric and cavity-like three dimensional structures. For arbitrary three dimensional geometries we introduce several new techniques and test them numerically. (Orig.)

Exploring International Students' Food Choices Using Photovoice Techniques

Science.gov (United States)

Corcoran, Nova

2018-01-01

This study aimed to explore international student food choices in a semirural setting using participatory photovoice techniques. Eighteen international students took photographs over 7-10 days of a typical food week and then attended a workshop where they completed three photography display and captioning tasks. Ten themes emerged linked to the…

Indirect three-dimensional printing of synthetic polymer scaffold based on thermal molding process

International Nuclear Information System (INIS)

Park, Jeong Hun; Jung, Jin Woo; Cho, Dong-Woo; Kang, Hyun-Wook

2014-01-01

One of the major issues in tissue engineering has been the development of three-dimensional (3D) scaffolds, which serve as a structural template for cell growth and extracellular matrix formation. In scaffold-based tissue engineering, 3D printing (3DP) technology has been successfully applied for the fabrication of complex 3D scaffolds by using both direct and indirect techniques. In principle, direct 3DP techniques rely on the straightforward utilization of the final scaffold materials during the actual scaffold fabrication process. In contrast, indirect 3DP techniques use a negative mold based on a scaffold design, to which the desired biomaterial is cast and then sacrificed to obtain the final scaffold. Such indirect 3DP techniques generally impose a solvent-based process for scaffold fabrication, resulting in a considerable increase in the fabrication time and poor mechanical properties. In addition, the internal architecture of the resulting scaffold is affected by the properties of the biomaterial solution. In this study, we propose an advanced indirect 3DP technique using projection-based micro-stereolithography and an injection molding system (IMS) in order to address these challenges. The scaffold was fabricated by a thermal molding process using IMS to overcome the limitation of the solvent-based molding process in indirect 3DP techniques. The results indicate that the thermal molding process using an IMS has achieved a substantial reduction in scaffold fabrication time and has also provided the scaffold with higher mechanical modulus and strength. In addition, cell adhesion and proliferation studies have indicated no significant difference in cell activity between the scaffolds prepared by solvent-based and thermal molding processes. (paper)

Indirect self-destructiveness in individuals with schizophrenia

Directory of Open Access Journals (Sweden)

Konstantinos Tsirigotis

2017-06-01

Full Text Available Objective: To explore the indirect self-destructiveness syndrome in patients with schizophrenia. Methods: Two hundred individuals with paranoid schizophrenia (117 men and 83 women, mean age 37.15 years, all in remission, were examined using the Polish version of the Chronic Self-Destructiveness Scale. Two hundred well-matched healthy individuals served as a control group. Results: The intensity of indirect self-destructiveness was greater in the schizophrenia group than in controls. The intensity of each manifestation was as follows (in decreasing order: helplessness and passiveness in the face of difficulties (A5, personal and social neglects (A3, lack of planfulness (A4, poor health maintenance (A2, transgression and risk (A1. Conclusion: Patients with schizophrenia displayed more behaviors that were indirectly self-destructive than healthy controls; they scored better than healthy controls only on caring for their own health. The patients showed the lowest intensity of behaviors connected with the active form of indirect self-destructiveness, and the highest intensity of behaviors connected with the passive form. These findings may enable delivery of more effective forms of pharmacological and psychosocial help to patients with schizophrenia.

Indirect MR arthrography of the shoulder in detection of rotator cuff ruptures

International Nuclear Information System (INIS)

Yagci, B.; Manisali, M.; Yilmaz, E.; Oezaksoy, D.; Kovanlikaya, I.; Oezkan, M.; Ekin, A.

2001-01-01

The aim of this study was to compare the efficacy of indirect MR arthrography images obtained following intravenous contrast injection and conventional MR imaging in the diagnosis of rotator cuff tears. Twenty-four patients with clinically suspected rotator cuff disease were examined. Conventional MR images and post-contrast indirect MR arthrography images were obtained. All images were evaluated in a blinded fashion by two musculoskeletal radiologist. Results were than analyzed depending on surgical output. The correlation coefficient (Spearman rank correlation test) and the kappa values for agreement between surgery and imaging techniques were calculated. The correlation coefficients between indirect MR arthrography and surgery for reader 1 and reader 2 were 0.9137 and 0.9773, respectively. Whereas the agreement between conventional MR imaging and surgery was moderate (κ=0.383-0.571), the agreement between indirect MR arthrography and surgery was excellent (κ=0.873-0.936). We suggest the use of indirect MR arthrography technique when conventional MR images are equivocal in diagnosis of rotator cuff disease. (orig.)

PELE:  Protein Energy Landscape Exploration. A Novel Monte Carlo Based Technique.

Science.gov (United States)

Borrelli, Kenneth W; Vitalis, Andreas; Alcantara, Raul; Guallar, Victor

2005-11-01

Combining protein structure prediction algorithms and Metropolis Monte Carlo techniques, we provide a novel method to explore all-atom energy landscapes. The core of the technique is based on a steered localized perturbation followed by side-chain sampling as well as minimization cycles. The algorithm and its application to ligand diffusion are presented here. Ligand exit pathways are successfully modeled for different systems containing ligands of various sizes:  carbon monoxide in myoglobin, camphor in cytochrome P450cam, and palmitic acid in the intestinal fatty-acid-binding protein. These initial applications reveal the potential of this new technique in mapping millisecond-time-scale processes. The computational cost associated with the exploration is significantly less than that of conventional MD simulations.

Evaluation of shrinkage polymerization and temperature of different acrylic resins used to splinting transfer copings in indirect impression technique

Science.gov (United States)

Franco, Ana Paula G. O.; Karam, Leandro Z.; Galvão, José R.; Kalinowski, Hypolito J.

2015-09-01

The aim of the present study was evaluate the shrinkage polymerization and temperature of different acrylic resins used to splinting transfer copings in indirect impression technique. Two implants were placed in an artificial bone, with the two transfer copings joined with dental floss and acrylic resins; two dental resins are used. Measurements of deformation and temperature were performed with Fiber Braggs grating sensor for 17 minutes. The results revealed that one type of resin shows greater values of polymerization shrinkage than the other. Pattern resins did not present lower values of shrinkage, as usually reported by the manufacturer.

Indirect reciprocity in three types of social dilemmas.

Science.gov (United States)

Nakamura, Mitsuhiro; Ohtsuki, Hisashi

2014-08-21

Indirect reciprocity is a key mechanism for the evolution of human cooperation. Previous studies explored indirect reciprocity in the so-called donation game, a special class of Prisoner's Dilemma (PD) with unilateral decision making. A more general class of social dilemmas includes Snowdrift (SG), Stag Hunt (SH), and PD games, where two players perform actions simultaneously. In these simultaneous-move games, moral assessments need to be more complex; for example, how should we evaluate defection against an ill-reputed, but now cooperative, player? We examined indirect reciprocity in the three social dilemmas and identified twelve successful social norms for moral assessments. These successful norms have different principles in different dilemmas for suppressing cheaters. To suppress defectors, any defection against good players is prohibited in SG and PD, whereas defection against good players may be allowed in SH. To suppress unconditional cooperators, who help anyone and thereby indirectly contribute to jeopardizing indirect reciprocity, we found two mechanisms: indiscrimination between actions toward bad players (feasible in SG and PD) or punishment for cooperation with bad players (effective in any social dilemma). Moreover, we discovered that social norms that unfairly favor reciprocators enhance robustness of cooperation in SH, whereby reciprocators never lose their good reputation. Copyright © 2014 Elsevier Ltd. All rights reserved.

School leadership effects revisited: a review of empirical studies guided by indirect-effect models

NARCIS (Netherlands)

Hendriks, Maria A.; Scheerens, Jaap

2013-01-01

Fourteen leadership effect studies that used indirect-effect models were quantitatively analysed to explore the most promising mediating variables. The results indicate that total effect sizes based on indirect-effect studies appear to be low, quite comparable to the results of some meta-analyses of

Application of the Indirect Immunoperoxidase Stain Technique to the Flagella of Azospirillum brasilense

Science.gov (United States)

Hall, Patrick G.; Krieg, Noel R.

1984-01-01

An indirect immunoperoxidase stain was used to demonstrate by electron microscopy that an antigenic difference exists between the polar flagellum and the lateral flagella of Azospirillum brasilense ATCC 29145. Images PMID:16346482

Manifestations of Indirect Self-Destructiveness and Dimensions of Emotional Intelligence.

Science.gov (United States)

Tsirigotis, Konstantinos; Łuczak, Joanna

2016-09-01

While indirect self-destructiveness exerts a rather negative influence on the life and psychological and social functioning of the individual, emotional intelligence may have a favourable effect. The aim of this study has been to explore possible relationships between manifestations of indirect self-destructiveness and dimensions of emotional intelligence. A population of 260 individuals (130 females and 130 males) aged 20-30 (mean age of 24.5) was studied by using the Polish version of the Chronic Self-Destructiveness Scale and INTE, i.e., the Polish version of the Assessing Emotions Scale. Manifestations of indirect self-destructiveness show many significant correlations with variables of the INTE, and those correlations are negative. Generally, it can be said that low emotional intelligence is associated with poor psychosocial and social functioning, which, in turn, is associated with indirect self-destructiveness and its manifestations. It seems advisable to use emotional intelligence in the prophylactic and therapeutic work with individuals suffering from various types of disorders, especially the syndrome of indirect self-destructiveness.

The Measure of Human Error: Direct and Indirect Performance Shaping Factors

Energy Technology Data Exchange (ETDEWEB)

Ronald L. Boring; Candice D. Griffith; Jeffrey C. Joe

2007-08-01

The goal of performance shaping factors (PSFs) is to provide measures to account for human performance. PSFs fall into two categories—direct and indirect measures of human performance. While some PSFs such as “time to complete a task” are directly measurable, other PSFs, such as “fitness for duty,” can only be measured indirectly through other measures and PSFs, such as through fatigue measures. This paper explores the role of direct and indirect measures in human reliability analysis (HRA) and the implications that measurement theory has on analyses and applications using PSFs. The paper concludes with suggestions for maximizing the reliability and validity of PSFs.

The tobacco industry's accounts of refining indirect tobacco advertising in Malaysia

OpenAIRE

Assunta, M; Chapman, S

2004-01-01

Objective: To explore tobacco industry accounts of its use of indirect tobacco advertising and trademark diversification (TMD) in Malaysia, a nation with a reputation for having an abundance of such advertising.

ADVANCED OPTICAL TECHNIQUES TO EXPLORE BRAIN STRUCTURE AND FUNCTION

OpenAIRE

Silvestri, L.; Mascaro, A. L. Allegra; Lotti, J.; Sacconi, L.; Pavone, F. S.

2013-01-01

Understanding brain structure and function, and the complex relationships between them, is one of the grand challenges of contemporary sciences. Thanks to their flexibility, optical techniques could be the key to explore this complex network. In this manuscript, we briefly review recent advancements in optical methods applied to three main issues: anatomy, plasticity and functionality. We describe novel implementations of light-sheet microscopy to resolve neuronal anatomy in whole fixed brain...

Fabrication of channeled scaffolds with ordered array of micro-pores through microsphere leaching and indirect Rapid Prototyping technique.

Science.gov (United States)

Tan, J Y; Chua, C K; Leong, K F

2013-02-01

Advanced scaffold fabrication techniques such as Rapid Prototyping (RP) are generally recognized to be advantageous over conventional fabrication methods in terms architectural control and reproducibility. Yet, most RP techniques tend to suffer from resolution limitations which result in scaffolds with uncontrollable, random-size pores and low porosity, albeit having interconnected channels which is characteristically present in most RP scaffolds. With the increasing number of studies demonstrating the profound influences of scaffold pore architecture on cell behavior and overall tissue growth, a scaffold fabrication method with sufficient architectural control becomes imperative. The present study demonstrates the use of RP fabrication techniques to create scaffolds having interconnected channels as well as controllable micro-size pores. Adopted from the concepts of porogen leaching and indirect RP techniques, the proposed fabrication method uses monodisperse microspheres to create an ordered, hexagonal closed packed (HCP) array of micro-pores that surrounds the existing channels of the RP scaffold. The pore structure of the scaffold is shaped using a single sacrificial construct which comprises the microspheres and a dissolvable RP mold that were sintered together. As such, the size of pores as well as the channel configuration of the scaffold can be tailored based on the design of the RP mold and the size of microspheres used. The fabrication method developed in this work can be a promising alternative way of preparing scaffolds with customized pore structures that may be required for specific studies concerning cell-scaffold interactions.

Robust indirect band gap and anisotropy of optical absorption in B-doped phosphorene.

Science.gov (United States)

Wu, Zhi-Feng; Gao, Peng-Fei; Guo, Lei; Kang, Jun; Fang, Dang-Qi; Zhang, Yang; Xia, Ming-Gang; Zhang, Sheng-Li; Wen, Yu-Hua

2017-12-06

A traditional doping technique plays an important role in the band structure engineering of two-dimensional nanostructures. Since electron interaction is changed by doping, the optical and electrochemical properties could also be significantly tuned. In this study, density functional theory calculations have been employed to explore the structural stability, and electronic and optical properties of B-doped phosphorene. The results show that all B-doped phosphorenes are stable with a relatively low binding energy. Of particular interest is that these B-doped systems exhibit an indirect band gap, which is distinct from the direct one of pure phosphorene. Despite the different concentrations and configurations of B dopants, such indirect band gaps are robust. The screened hybrid density functional HSE06 predicts that the band gap of B-doped phosphorene is slightly smaller than that of pure phosphorene. Spatial charge distributions at the valence band maximum (VBM) and the conduction band minimum (CBM) are analyzed to understand the features of an indirect band gap. By comparison with pure phosphorene, B-doped phosphorenes exhibit strong anisotropy and intensity of optical absorption. Moreover, B dopants could enhance the stability of Li adsorption on phosphorene with less sacrifice of the Li diffusion rate. Our results suggest that B-doping is an effective way of tuning the band gap, enhancing the intensity of optical absorption and improving the performances of Li adsorption, which could promote potential applications in novel optical devices and lithium-ion batteries.

Lymphocyte labelling technique for the exploration of kidney transplants

International Nuclear Information System (INIS)

Guey, A.; Touraine, J.L.; Collard, M.; Claveyrolas, P.; Bouteiller, O. de; Traeger, J.

The labelling technique is developed with a precise clinical exploration in view and has to take into account the following rules or conditions: - the blood sample must be smaller than 20 ml; - the manipulation must not last more than 3 hours; - the immunological properties of the labelled lymphocytes must be kept intact; - the solution reinjected into the patient must contain no aggregates, be absolutely sterile and possess a radioactivity above 1mCi. The technique of extraction and labelling from a sample of about 15ml is described. The main factors responsible for the quality of the labelling are analysed, together with the labelling and irradiation dose effects on certain properties of the lymphocytes (viability, rosette E formation, proliferative response to mitogens) [fr

Interactive Exploration of Big Scientific Data: New Representations and Techniques.

Science.gov (United States)

Hjelmervik, Jon M; Barrowclough, Oliver J D

2016-01-01

Although splines have been in popular use in CAD for more than half a century, spline research is still an active field, driven by the challenges we are facing today within isogeometric analysis and big data. Splines are likely to play a vital future role in enabling effective big data exploration techniques in 3D, 4D, and beyond.

Clinical performance of direct versus indirect composite restorations in posterior teeth: A systematic review.

Science.gov (United States)

Azeem, Rubeena Abdul; Sureshbabu, Nivedhitha Malli

2018-01-01

Composite resin, serves as esthetic alternative to amalgam and cast restorations. Posterior teeth can be restored using direct or indirect composite restorations. The selection between direct and indirect technique is a clinically challenging decision-making process. Most important influencing factor is the amount of remaining tooth substance. The aim of this systematic review was to compare the clinical performance of direct versus indirect composite restorations in posterior teeth. The databases searched included PubMed CENTRAL (until July 2015), Medline, and Cochrane Database of Systematic Reviews. The bibliographies of clinical studies and reviews identified in the electronic search were analyzed to identify studies which were published outside the electronically searched journals. The primary outcome measure was evaluation of the survival of direct and indirect composite restorations in posterior teeth. This review included thirteen studies in which clinical performance of various types of direct and indirect composite restorations in posterior teeth were compared. Out of the thirteen studies which were included seven studies had a high risk of bias and five studies had a moderate risk of bias. One study having a low risk of bias, concluded that there was no significant difference between direct and indirect technique. However, the available evidence revealed inconclusive results. Further research should focus on randomized controlled trials with long term follow-up to give concrete evidence on the clinical performce of direct and indirect composite restorations.

Treatment of Moya Moya disease using indirect surgery technique

Directory of Open Access Journals (Sweden)

Cezary Grochowski

2016-08-01

Conclusion: Presented technique is preferred among children suffering from moya moya disease because of the safety of the technique and good treatment effects. There is no need to perform by-pass surgery which is also considered as big advantage of presented technique.

Heard it through the grapevine: indirect networks and employee creativity.

Science.gov (United States)

Hirst, Giles; Van Knippenberg, Daan; Zhou, Jing; Quintane, Eric; Zhu, Cherrie

2015-03-01

Social networks can be important sources of information and insights that may spark employee creativity. The cross-fertilization of ideas depends not just on access to information and insights through one's direct network-the people one actually interacts with--but at least as much on access to the indirect network one's direct ties connect one to (i.e., people one does not interact with directly, but with whom one's direct ties interact). We propose that the reach efficiency of this indirect network--its nonredundancy in terms of interconnections--is positively related to individual creativity. To help specify the boundaries of this positive influence of the indirect network, we also explore how many steps removed the indirect network still adds to creativity. In addition, we propose that the efficiency (nonredundancy) of one's direct network is important here, because more efficient direct networks give one access to indirect networks with greater reach efficiency. Our hypotheses were supported in a multilevel analysis of multisource survey data from 223 sales representatives nested within 11 divisions of a Chinese pharmaceutical company. This analysis also showed that the creative benefits of reach efficiency were evident for 3 and 4 degrees of separation but were greatest for indirect ties that depend only on one's direct ties. PsycINFO Database Record (c) 2015 APA, all rights reserved.

Determination of boron in water solution by an indirect neutron activation technique from a 241Am/Be source

International Nuclear Information System (INIS)

Sales, H.B.

1981-08-01

Boron content in water solutions has been analysed by Indirect Activation Technique a twin 241 Am/Be neutron source with a source strength of 9x10 6 n/seg. The boron concentration was inferred from the measurement of the activity induced in a vanadium flux monitor. The vanadium rod was located inside the boron solution in a standart geometrical set up with respect to the neutron source. Boron concentrations in the range of 100 to 1000 ppm were determined with an overall accuracy of about 2% during a total analysis time of about 20 minutes. Eventhough the analysis is not selective for boron yet due the rapid, simple and precise nature, it is proposed for the analysis of boron in the primary coolant circuit of Nuclear Power Plants of PWR type. (Author) [pt

Adaptive evolution of body size subject to indirect effect in trophic cascade system.

Science.gov (United States)

Wang, Xin; Fan, Meng; Hao, Lina

2017-09-01

Trophic cascades represent a classic example of indirect effect and are wide-spread in nature. Their ecological impact are well established, but the evolutionary consequences have received even less theoretical attention. We theoretically and numerically investigate the trait (i.e., body size of consumer) evolution in response to indirect effect in a trophic cascade system. By applying the quantitative trait evolutionary theory and the adaptive dynamic theory, we formulate and explore two different types of eco-evolutionary resource-consumer-predator trophic cascade model. First, an eco-evolutionary model incorporating the rapid evolution is formulated to investigate the effect of rapid evolution of the consumer's body size, and to explore the impact of density-mediate indirect effect on the population dynamics and trait dynamics. Next, by employing the adaptive dynamic theory, a long-term evolutionary model of consumer body size is formulated to evaluate the effect of long-term evolution on the population dynamics and the effect of trait-mediate indirect effect. Those models admit rich dynamics that has not been observed yet in empirical studies. It is found that, both in the trait-mediated and density-mediated system, the body size of consumer in predator-consumer-resource interaction (indirect effect) evolves smaller than that in consumer-resource and predator-consumer interaction (direct effect). Moreover, in the density-mediated system, we found that the evolution of consumer body size contributes to avoiding consumer extinction (i.e., evolutionary rescue). The trait-mediate and density-mediate effects may produce opposite evolutionary response. This study suggests that the trophic cascade indirect effect affects consumer evolution, highlights a more comprehensive mechanistic understanding of the intricate interplay between ecological and evolutionary force. The modeling approaches provide avenue for study on indirect effects from an evolutionary perspective

RESEMBLANCE OF INDIRECTNESS IN POLITENESS OF EFL LEARNERS’ REQUEST REALIZATIONS

Directory of Open Access Journals (Sweden)

Indawan Syahri

2013-07-01

Full Text Available Abstract: Politeness principles are universally utilized by the speakers of any language when realizing various speech acts. However, the speakers of particular languages relatively apply politeness due to the cultural norms embedded. The present study attempts to delineate how the Indonesian learners of English (ILE apply the politeness principles in request realizations. Specifically it devotes to the types of politeness strategies applied and resemblance of the indirectness in politeness strategies in requesting acts. The FTAs and indirectness are the theoretical bases used to trace the typologies of both politeness and request strategies. The data werere collected by means of certain elicitation techniques, i.e. DCTs and Role-plays. The analyses werere done through three stages; determining request strategies, politeness strategies, and resemblance of indirectness in politeness. The results show that the indirectness generally is parallel to politeness. Besides, some pragmatic transfers are found in terms of applying native-culture norms in realizing target speech acts.

Software Prefetching for Indirect Memory Accesses

OpenAIRE

Ainsworth, Sam; Jones, Timothy

2017-01-01

Many modern data processing and HPC workloads are heavily memory-latency bound. A tempting proposition to solve this is software prefetching, where special non-blocking loads are used to bring data into the cache hierarchy just before being required. However, these are difficult to insert to effectively improve performance, and techniques for automatic insertion are currently limited. This paper develops a novel compiler pass to automatically generate software prefetches for indirect mem...

Mississippi exploration field trials using microbial, radiometrics, free soil gas, and other techniques

Energy Technology Data Exchange (ETDEWEB)

Moody, J.S.; Brown, L.R.; Thieling, S.C.

1995-12-31

The Mississippi Office of Geology has conducted field trials using the surface exploration techniques of geomicrobial, radiometrics, and free soil gas. The objective of these trials is to determine if Mississippi oil and gas fields have surface hydrocarbon expression resulting from vertical microseepage migration. Six fields have been surveyed ranging in depth from 3,330 ft to 18,500 ft. The fields differ in trapping styles and hydrocarbon type. The results so far indicate that these fields do have a surface expression and that geomicrobial analysis as well as radiometrics and free soil gas can detect hydrocarbon microseepage from pressurized reservoirs. All three exploration techniques located the reservoirs independent of depth, hydrocarbon type, or trapping style.

Indirection and computer security.

Energy Technology Data Exchange (ETDEWEB)

Berg, Michael J.

2011-09-01

The discipline of computer science is built on indirection. David Wheeler famously said, 'All problems in computer science can be solved by another layer of indirection. But that usually will create another problem'. We propose that every computer security vulnerability is yet another problem created by the indirections in system designs and that focusing on the indirections involved is a better way to design, evaluate, and compare security solutions. We are not proposing that indirection be avoided when solving problems, but that understanding the relationships between indirections and vulnerabilities is key to securing computer systems. Using this perspective, we analyze common vulnerabilities that plague our computer systems, consider the effectiveness of currently available security solutions, and propose several new security solutions.

Electronic techniques for subsea oil exploration and extraction

Energy Technology Data Exchange (ETDEWEB)

1976-01-01

Subsea oil exploration and extraction is becoming increasingly difficult, costly, and dangerous. Electronics is contributing to make offshore work easier and safer. It is used for positioning ships or oil rigs, for remotely controlling well-heads and tool reentry operations, for pipelaying operations, and for monitoring underwater equipment. It is also tending to replace men in diving operations. The specific achievements of THOMPSON--CSF in this field are described. Fully automated operation of the winches on the ETPM 1601 barge proved successful during a recent pipelaying operation. The technique used by THOMPSON--CSF in this venture allowed a single operator to control all the maneuvers. These are briefly described. (MCW)

SPSS and SAS procedures for estimating indirect effects in simple mediation models.

Science.gov (United States)

Preacher, Kristopher J; Hayes, Andrew F

2004-11-01

Researchers often conduct mediation analysis in order to indirectly assess the effect of a proposed cause on some outcome through a proposed mediator. The utility of mediation analysis stems from its ability to go beyond the merely descriptive to a more functional understanding of the relationships among variables. A necessary component of mediation is a statistically and practically significant indirect effect. Although mediation hypotheses are frequently explored in psychological research, formal significance tests of indirect effects are rarely conducted. After a brief overview of mediation, we argue the importance of directly testing the significance of indirect effects and provide SPSS and SAS macros that facilitate estimation of the indirect effect with a normal theory approach and a bootstrap approach to obtaining confidence intervals, as well as the traditional approach advocated by Baron and Kenny (1986). We hope that this discussion and the macros will enhance the frequency of formal mediation tests in the psychology literature. Electronic copies of these macros may be downloaded from the Psychonomic Society's Web archive at www.psychonomic.org/archive/.

Silent, indirect strategic processes in small and medium sized enterprises

DEFF Research Database (Denmark)

Larsen, Mette Vinther; Madsen, Charlotte Øland; Rasmussen, Jørgen Gulddahl

Based on empirical data we in this paper explore day-to-day strategising with an emphasis on phronesis. This way we shed some light on the nearly silent, quiet, indirect strategic change processes as they are practiced and reflected upon by leaders in small companies in their daily practice...

New thermoluminescence techniques for mineral exploration

International Nuclear Information System (INIS)

Levy, P.W.; Holmes, R.J.; Ypma, P.J.; Chen, C.C.; Swiderski, H.S.

1977-01-01

The thermoluminescence of carbonate host rock in the vicinity of known lead-zinc and lead-zinc-fluorite mineralization was reexamined for possible development as an exploration technique. The measurements were made with equipment for determining the thermoluminescence spectrum at closely spaced temperature intervals. Radiation-induced thermoluminescence was also measured. Samples were studied from five localities in Mexico, Southwest Africa, and the United States. Four thermoluminescence properties were found to vary with ''distance-from-ore'' in a systematic manner. These include the glow peak intensity and temperature and the emission spectrum peak energy and full width at half-maximum. For example, in both limestone and dolomite, the high-temperature glow peak intensities are low or negligible within the ore and as the distance from the contact increases the intensity rises rapidly to a maximum, or maxima, and then decreases irregularly to constant value slightly above that in the ore. Depending on the thickness of the ore, the thermoluminescence characteristics associated with the mineralization extended from ten to a hundred or so meters from the ore host rock contact. 5 figures

The indirect effects of cheatgrass invasion: Grasshopper herbivory on native grasses determined by neighboring cheatgrass abundance

Science.gov (United States)

Julie Beckstead; Susan E. Meyer; Carol K. Augsperger

2008-01-01

Invasion biology has focused on the direct effects of plant invasion and has generally overlooked indirect interactions. Here we link theories of invasion biology and herbivory to explore an indirect effect of one invading species on associational herbivory (the effect of neighboring plants on herbivory) of native species. We studied a Great Basin shadscale (...

Application of exploration geochemistry techniques in agriculture

International Nuclear Information System (INIS)

Santos, G.P. Jr.; Fernandez, L.G.; Petrache, C.A.; Almoneda, R.V.; Rosales, C.M.

1989-01-01

Soil samples collected from Tarlac, Nueva Ecija, Pampanga, Bulacan, Laguna and Quezon provinces were analyzed for Zn, Mn, Cu, Fe, Co, Pb, and Ni using two analytical methods - Smith and Lynch (S and L) element extraction technique used in exploration geochemical survey and the International Rice Research Institute (IRRI) technique for determining zinc availability in soil. The analytical results were treated statistically using the method of Lepeltier to obtain the background values. The background, or average concentrations of the elements obtained by the S and L method were an order-higher than those computed for the IRRI method. The different metal value contour maps of northwestern Luzon were multiplied by its corresponding metal ratio, IRRI/S and L to produce the agri-geochemical maps or agri-maps that show approximate trace element levels available to the plant. The agri-maps of northwestern Luzon show a region wide deficiency in Cu, Zn, Mn, Pb, Co, and Ni, with the exception of Baguio Area. It has been recognized that excess deficiency in certain minor or trace elements in, particularly the essential micronutrient elements, is one of the important factors in agricultural productivity. It is therefore, recommended that in order to assure the necessary level of trace elements in northwestern Luzon, additions of at least copper, zinc and manganese be provided together with the needed fertilizer. (Author). 14 figs.; 14 refs.; 4 tabs

SUCCESS RATE OF ONE SESSION AND TWO SESSION TECHNIQUES FOR TREATMENT OF ASYMPTOMATIC PULPITIS OF PRIMARY TEETH WITH INDIRECT PULP CAPPING.

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Rossitza Kabaktchieva

2013-01-01

Full Text Available Objective: Objective: To compare the success rate between the one session and two session indirect pulp capping of asymptomatic pulpitis for 1 year after the treatment was performed in children with different caries risk. Material and Methods: The children and the teeth were selected according to certain criteria for inclusion in the study. According to that, 72 children with low, moderate and high caries risk were included and 131 teeth with asymptomatic pulpitis were treated. The clinical protocols for indirect pulp capping (IPC in one session and two sessions were defined. The review appointments were performed 6 and 12 months after the treatment using certain clinical and radiographic criteria which defined success or post-treatment complications. The results are statistically analysed using One Sided Exact Two-Proportion Test with 95% Significance level (5% risk of type I error. Results: The statistical test showed that between the compared success rates of the one session and two sessions IPC, on the 6th and 12th month, there wasn’t a significant difference (p>0.05. This was valid for every one of the examined groups of patients (p>0. 05. This proves that there is no difference in the success rates of treatment of pulpitis in primary teeth using one or two sessions. Conclusions: The results about the success of treatment of asymptomatic pulpitis in primary teeth during one or two sessions have confirmed the results showed in other current studies. Our study has confirmed (clinically and radiographically the success of both techniques and we have concluded that in children with high caries risk, more appropriate technique is the one performed in two sessions. Treatment in one session is recommended in children with low or moderate caries risk.

Indirect calorimetry: assessing animal response to heat and cold stress

NARCIS (Netherlands)

Gaughan, J.B.; Heetkamp, M.J.W.; Hendriks, P.

2015-01-01

Calorimetric thermal stress studies where indirect calorimetry is used as a tool to estimate energy expenditure have been undertaken since this technique was developed. Some examples of these studies are presented in this chapter. The measurement of gas exchange by means of an open-circuit

Indirect Lymphography and its Importance in Oncology; La Lymphographie Indirecte et son Interet en Oncologie; Kosvennaya limfografiya i ee znachenie v onkologii; La Linfografia Indirecta y su Interes en Oncologia

Energy Technology Data Exchange (ETDEWEB)

Delaloye, B.; Magnenat, P. [Laboratoire des Radioisotopes, Clinique Medicale Universitaire de Lausanne, Lausanne (Switzerland)

1964-10-15

Indirect lymphography, which only requires a subcutaneous injection of colloidal gold-198 with a particle diameter of 50 A in the tributary region of the lymphatic system being explored, makes possible, by scintigraphic recording, a clear representation of the ganglionic lymphatic chains. The problems of collimation in getting optimum definition are discussed. With this method of investigating the lymphatic system, measurement of the time of appearance of the gold in the blood yields indirect information regarding the rate of transit of the colloidal gold particles in the lymphatic vessels. Useful information is also obtained on neoplastic infiltrations of the ganglia and hence it is possible to determine the extent of a metastatic infiltration. Clinical examples are described. In addition, the authors describe a new technique for hepatic lymphography by the transcutaneous, sub-capsular injection of colloidal gold-198. This technique reveals the anterior and posterior mediastinal lymphatic chains. (author) [French] La lymphographie indirecte, qui ne necessite qu'une injection sous-cutanee d'or-198 colloiedal dont le diametre des particules est de 50 Adans le territoire tributaire du systeme lymphatique que l'on veut explorer, permet par enregistrement scintigraphique une bonne mise en evidence des chaines ganglionnaires lymphatiques. Les problemes de collimation sont discutes afin d'obtenir la meilleure definition possible. Ce mode d'investigation du systeme lymphatique permet, lorsqu'on mesure le temps d'apparition de l'or dans le sang, d'obtenir indirectement des renseignements sur la vitesse du transit des particules d'or colloiedal dans les vaisseaux lymphatiques. On obtient egalement d'utiles renseignements sur les infiltrations neoplastiques des ganglions et, de ce fait, il est possible de connaitre l'etendue d'une infiltration metastatique. Des exemples cliniques sont decrits. De plus, les auteurs decrivent une nouvelle technique de lymphogtaphie hepatique

Multimedia Storytelling in Journalism: Exploring Narrative Techniques in Snow Fall

Directory of Open Access Journals (Sweden)

Kobie van Krieken

2018-05-01

Full Text Available News stories aim to create an immersive reading experience by virtually transporting the audience to the described scenes. In print journalism, this experience is facilitated by text-linguistic narrative techniques, such as detailed scene reconstructions, a chronological event structure, point-of-view writing, and speech and thought reports. The present study examines how these techniques are translated into journalistic multimedia stories and explores how the distinctive features of text, image, video, audio, and graphic animations are exploited to immerse the audience in otherwise distant news events. To that end, a case study of the New York Times multimedia story Snow Fall is carried out. Results show that scenes are vividly reconstructed through a combination of text, image, video, and graphic animation. The story’s event structure is expressed in text and picture, while combinations of text, video, and audio are used to represent the events from the viewpoints of news actors. Although text is still central to all narrative techniques, it is complemented with other media formats to create various multimedia combinations, each intensifying the experience of immersion.

Direct or indirect - that is the question!

DEFF Research Database (Denmark)

Pallesen, Ulla

2016-01-01

Time has passed since the prevention of caries was performed by extending cavity preparations wide in the tooth and below the gingiva. In the same period adhesive techniques have improved and nowadays made it possible to extend the indications for direct composite resin restorations, also when...... rather destroyed teeth need to be restored. Although much can be solved by direct fillings and thereby make treatments less invasive for the tooth and less expensive for the patient, there still will be teeth, where the prognosis is improved, if an indirect restoration in terms of an inlay, onlay...... or crown is made. Factors as remaining tooth structure, endodontic treatment, number of teeth, caries risk, para-functional habits, material properties, economy etc. will all have an influence, when the dentist guides the patient to choose the best solution. What is best for the tooth – direct or indirect...

Indirect Consequences of Recreational Fishing in Freshwater Ecosystems: An Exploration from an Australian Perspective

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Shelley Burgin

2017-02-01

Full Text Available Recreational fishing in freshwater ecosystems is a popular pastime in Australia. Although most native fish are endemic, the fauna is depauperate compared to any landmass of similar size. With commercial fishing no longer a major industry in the country’s freshwaters, the future sustainability of these ecosystems will depend heavily on the actions of recreational fishers. However, there has been limited focus on the consequences of recreational fishing in freshwaters. There is particularly a dearth of information on the indirect consequences of fishers on the waterbodies they depend on for their sport. After outlining the respective trends in commercial and recreational fishing in Australia as a basis for placing the sport in context, the indirect impacts of fishers on water quality, movement (walking, off-road vehicles, the introduction/translocation of fauna (particularly fish, the dispersal of flora and the transmission of fish disease and pathogens are reviewed. It is concluded that with the decline of commercial fishing, the competition between commercial fin-fishing and recreational fishing is negligible, at least throughout most of the country. It is also concluded that each of the issues addressed has the potential to be detrimental to the long-term sustainability of the freshwater ecosystems that the fishers depend on for their recreation. However, information on these issues is scant. This is despite the current and predicted popularity of freshwater recreational fishing continuing to increase in Australia. Indeed, there has been insufficient quantitative assessment of the impacts to even determine what is required to ensure a comprehensive, adequate and representative protection of these freshwater ecosystems. To underpin the sustainability of inland recreational fishing in the country, it was concluded that research is required to underpin the development and implementation of appropriate policies. The alternative is that the

"Whole" Ballet Education: Exploring Direct and Indirect Teaching Methods

Science.gov (United States)

Choi, Euichang; Kim, Na-ye

2015-01-01

The purpose of this study was to explore teaching methods for whole ballet in Korean ballet education. This study built upon a first phase of research that identified the educational content of "whole" ballet. Four dimensions were identified as the educational content: "physical," "cognitive," "emotional"…

Linking Contextual Factors with Rhetorical Pattern Shift: Direct and Indirect Strategies Recommended in English Business Communication Textbooks in China

Science.gov (United States)

Wang, Junhua; Zhu, Pinfan

2011-01-01

Scholars have consistently claimed that rhetorical patterns are culturally bound, and indirectness is a defining characteristic of Chinese writing. Through examining how the rhetorical mechanism of directness and indirectness is presented in 29 English business communication textbooks published in China, we explore how English business…

Indirect reduction technique using a distraction support in minimally invasive percutaneous plate osteosynthesis of tibial shaft fractures.

Science.gov (United States)

Dong, Wen-Wei; Shi, Zeng-Yuan; Liu, Zheng-Xin; Mao, Hai-Jiao

2016-12-01

To describe an indirect reduction technique during minimally invasive percutaneous plate osteosynthesis (MIPPO) of tibial shaft fractures with the use of a distraction support. Between March 2011 and October 2014, 52 patients with a mean age of 48 years (16-72 years) sustaining tibial shaft fractures were included. All the patients underwent MIPPO for the fractures using a distraction support prior to insertion of the plate. Fracture angular deformity was assessed by goni- ometer measurement on preoperative and postoperative images. Preoperative radiographs revealed a mean of 7.6°(1.2°-28°) angulation in coronal plane and a mean of 6.8°(0.5°-19°) angulation in sagittal plane. Postoperative anteroposterior and lateral radio- graphs showed a mean of 0.8°(0°-4.0°) and 0.6°(0°-3.6°) of varus/valgus and apex anterior/posterior angulation, respectively. No intraoperative or postoperative complications were noted. This study suggests that the distraction support during MIPPO of tibial shaft fractures is an effective and safe method with no associated complications.

Analysis of Indirect Emissions Benefits of Wind, Landfill Gas, and Municipal Solid Waste Generation

Science.gov (United States)

Techniques are introduced to calculate the hourly indirect emissions benefits of three types of green power resources: wind energy, municipal solid waste (MSW) combustion, and landfill gas (LFG) combustion. These techniques are applied to each of the U.S. EPA's eGRID subregions i...

Estimating forest canopy bulk density using six indirect methods

Science.gov (United States)

Robert E. Keane; Elizabeth D. Reinhardt; Joe Scott; Kathy Gray; James Reardon

2005-01-01

Canopy bulk density (CBD) is an important crown characteristic needed to predict crown fire spread, yet it is difficult to measure in the field. Presented here is a comprehensive research effort to evaluate six indirect sampling techniques for estimating CBD. As reference data, detailed crown fuel biomass measurements were taken on each tree within fixed-area plots...

Evaluation of the Acridine Orange Fluorescence Technique and the Indirect Fluorescent Antibody as Diagnostic Tests for Tropical Theileriosis

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Mahmoud

2011-06-01

Full Text Available This study was carried out to evaluate the use of acridine orange fluorescence technique on blood slides as a rapid diagnostic test for tropical theileriosis in comparison with the Giemsa-stained thin blood film technique. Also the indirect fluorescent antibody test has been employed for the serodiagnosis of tropical theileriosis. The study was carried out on 62 young and 48 adult Friesian cattle suffering from clinical tropical theileriosis in Qassim Region, Central Saudi Arabia, during the period from August 2006 to July 2008. For control, blood samples were also obtained from 25 young and 25 adult, clinically healthy, Friesian cattle, selected at random from different dairy farms in Qassim Region. Thin blood films were fixed with methanol and stained with Giemsa and acridine orange and were examined by two independent microbiologists. There was 100% correlation in the interpretation of slides stained with Giemsa and acridine orange both with respect to positivity and negativity, between the two microbiologists. It is concluded that if facilities are available acridine orange is a valuable alternative for screening tropical theileriosis. The method may also have potential value in the diagnosis of Theileria parva, which causes East Coast fever, and also other Theileria species. Results of the present study also showed that IFA test was not found sufficiently sensitive and specific as has been reported earlier. [Vet. World 2011; 4(8.000: 341-344

Cruel intentions on television and in real life: can viewing indirect aggression increase viewers' subsequent indirect aggression?

Science.gov (United States)

Coyne, Sarah M; Archer, John; Eslea, Mike

2004-07-01

Numerous studies have shown that viewing violence in the media can influence an individual's subsequent aggression, but none have examined the effect of viewing indirect aggression. This study examines the immediate effect of viewing indirect and direct aggression on subsequent indirect aggression among 199 children ages 11 to 14 years. They were shown an indirect, direct, or no-aggression video and their subsequent indirect aggression was measured by negative evaluation of a confederate and responses to a vignette. Participants viewing indirect or direct aggression gave a more negative evaluation of and less money to a confederate than participants viewing no-aggression. Participants viewing indirect aggression gave less money to the confederate than those viewing direct aggression. Participants viewing indirect aggression gave more indirectly aggressive responses to an ambiguous situation and participants viewing direct aggression gave more directly aggressive responses. This study provides the first evidence that viewing indirect aggression in the media can have an immediate impact on subsequent aggression.

Estimation of indirect effect when the mediator is a censored variable.

Science.gov (United States)

Wang, Jian; Shete, Sanjay

2017-01-01

A mediation model explores the direct and indirect effects of an initial variable ( X) on an outcome variable ( Y) by including a mediator ( M). In many realistic scenarios, investigators observe censored data instead of the complete data. Current research in mediation analysis for censored data focuses mainly on censored outcomes, but not censored mediators. In this study, we proposed a strategy based on the accelerated failure time model and a multiple imputation approach. We adapted a measure of the indirect effect for the mediation model with a censored mediator, which can assess the indirect effect at both the group and individual levels. Based on simulation, we established the bias in the estimations of different paths (i.e. the effects of X on M [ a], of M on Y [ b] and of X on Y given mediator M [ c']) and indirect effects when analyzing the data using the existing approaches, including a naïve approach implemented in software such as Mplus, complete-case analysis, and the Tobit mediation model. We conducted simulation studies to investigate the performance of the proposed strategy compared to that of the existing approaches. The proposed strategy accurately estimates the coefficients of different paths, indirect effects and percentages of the total effects mediated. We applied these mediation approaches to the study of SNPs, age at menopause and fasting glucose levels. Our results indicate that there is no indirect effect of association between SNPs and fasting glucose level that is mediated through the age at menopause.

Avaliação da força de tração em braquetes colados pela técnica indireta com diferentes sistemas de adesão Evaluation of tensile strength of brackets bonded by indirect technique

Directory of Open Access Journals (Sweden)

André Tortamano

2007-06-01

Full Text Available OBJETIVO: o objetivo do presente estudo foi avaliar a resistência à tração de braquetes ortodônticos colados pela técnica indireta e pela técnica direta convencional. METODOLOGIA: foram utilizados 50 pré-molares humanos íntegros, recém-extraídos por motivos ortodônticos. Esses dentes foram divididos em 5 grupos, nos quais foram colados braquetes ortodônticos metálicos (Abzil-Brasil com as resinas compostas ortodônticas Concise (3M-Unitek-EUA e Transbond XT (3M-Unitek-EUA - utilizadas em ambas as técnicas, direta e indireta - e Transbond Sondhi (3M-Unitek-EUA - desenvolvida exclusivamente para a técnica indireta. O grupo I (controle I foi objeto de colagem direta com Transbond XT; no grupo II (controle II procedeu-se à colagem direta com Concise o grupo III recebeu colagem indireta com Concise; o grupo IV foi submetido à colagem indireta com Transbond XT e no grupo V foi realizada colagem indireta com Transbond Sondhi. Na técnica direta, o braquete foi colado diretamente sobre o esmalte após condicionamento ácido e aplicação de adesivo. Na técnica indireta, os braquetes foram colados primeiramente sobre modelo de gesso e depois transferidos para o dente, com o auxílio de moldeira individualizada. Os corpos-de-prova foram submetidos a testes de tração (Instron 4400 e os resultados foram objeto de testes estatísticos de análise de variância e de Tukey a 1%. RESULTADOS: os grupos III e V revelaram resultados significantemente menores que os dos dois grupos controles. CONCLUSÃO: a força obtida na colagem indireta com a resina Transbond XT não difere da força obtida na colagem direta com as resinas Concise e Transbond XT.AIM: The purpose of this study was to evaluate the bonding strength of brackets for direct and indirect bonding techniques. METHODS: Were used 50 human premolars recently extracted for orthodontic reasons. These teeth were divided in 5 groups and metalic orthodontic brackets (Abzil-Brazil were bonded

Comparison of the marginal adaptation of direct and indirect composite inlay restorations with optical coherence tomography.

Science.gov (United States)

Türk, Ayşe Gözde; Sabuncu, Metin; Ünal, Sena; Önal, Banu; Ulusoy, Mübin

2016-01-01

The purpose of the study was to use the photonic imaging modality of optical coherence tomography (OCT) to compare the marginal adaptation of composite inlays fabricated by direct and indirect techniques. Class II cavities were prepared on 34 extracted human molar teeth. The cavities were randomly divided into two groups according to the inlay fabrication technique. The first group was directly restored on cavities with a composite (Esthet X HD, Dentsply, Germany) after isolating. The second group was indirectly restored with the same composite material. Marginal adaptations were scanned before cementation with an invisible infrared light beam of OCT (Thorlabs), allowing measurement in 200 µm intervals. Restorations were cemented with a self-adhesive cement resin (SmartCem2, Dentsply), and then marginal adaptations were again measured with OCT. Mean values were statistically compared by using independent-samples t-test and paired samples t-test (pmarginal discrepancy values than indirect inlays, before (p=0.00001442) and after (p=0.00001466) cementation. Marginal discrepancy values were increased for all restorations after cementation (p=0.00008839, p=0.000000952 for direct and indirect inlays, respectively). The mean marginal discrepancy value of the direct group increased from 56.88±20.04 µm to 91.88±31.7 µm, whereas the indirect group increased from 107.54±35.63 µm to 170.29±54.83 µm. Different techniques are available to detect marginal adaptation of restorations, but the OCT system can give quantitative information about resin cement thickness and its interaction between tooth and restoration in a nondestructive manner. Direct inlays presented smaller marginal discrepancy than indirect inlays. The marginal discrepancy values were increased for all restorations that refer to cement thickness after cementation.

Smartphone Image Acquisition During Postmortem Monocular Indirect Ophthalmoscopy.

Science.gov (United States)

Lantz, Patrick E; Schoppe, Candace H; Thibault, Kirk L; Porter, William T

2016-01-01

The medical usefulness of smartphones continues to evolve as third-party applications exploit and expand on the smartphones' interface and capabilities. This technical report describes smartphone still-image capture techniques and video-sequence recording capabilities during postmortem monocular indirect ophthalmoscopy. Using these devices and techniques, practitioners can create photographic documentation of fundal findings, clinically and at autopsy, without the expense of a retinal camera. Smartphone image acquisition of fundal abnormalities can promote ophthalmological telemedicine--especially in regions or countries with limited resources--and facilitate prompt, accurate, and unbiased documentation of retinal hemorrhages in infants and young children. © 2015 American Academy of Forensic Sciences.

Comparison between energy dispersive X-ray fluorescence and other nuclear analytical techniques in mineral exploration and mining

International Nuclear Information System (INIS)

Clayton, C.G.; Packer, T.W.; Wormald, M.R.

1979-01-01

At the present time there is an increasing awareness of the value and need for in-situ analytical methods throughout the general area of mineral exploration and mining. Of the alternative techniques, the measurement of natural gamma radiation is well established for uranium exploration and it is now being developed for sea-bed and lake-bed surveying. Energy dispersive X-ray fluorescence equipment is becoming more generally accepted, especially for mine control. Neutron techniques, for so long used routinely in oil well logging, are now being developed for a wide range of applications in all aspects of exploration and mining. It is believed that these techniques will result in major applications in the future. The present paper compares the principal characteristics of energy dispersive X-ray fluorescence and neutron techniques in particular, with special emphasis being given to those factors which affect the accuracy of analytical content; such as elemental resolution, matrix effects, material heterogeneity and neutron transport. A generalised comparison between the techniques is difficult to achieve because of the different nature of radiation interactions, but a range of applications is described and these show the complementary nature of the methods and point to the areas for more active development in the future. (author)

A Comparison of implant impression precision: Different materials and techniques

Science.gov (United States)

Tabesh, Mahtab; Alikhasi, Marzieh

2018-01-01

Background Precision of implant impressions is a prerequisite for long-term success of implant supported prostheses. Impression materials and impression techniques are two important factors that impression precision relies on. Material and Methods A model of edentulous maxilla containing four implants inserted by All-on-4 guide was constructed. Seventy two impressions using polyether (PE), polyvinyl siloxane (PVS), and vinyl siloxanether (VSE) materials with direct and indirect techniques were made (n=12). Coordinates of implants in casts were measured using coordinate measuring machine (CMM). Data were analyzed with ANOVA; t-test and Tukey test were used for post hoc. Results With two-way ANOVA, mean values of linear displacements of implants were significantly different among materials and techniques. One-way ANOVA and Tukey showed significant difference between PE and VSE (P=0.019), PE and PVS (P=0.002) in direct technique, and between PVS and PE (Pimpression of implants, PE is recommended for direct technique while PE and VSE are recommended for indirect technique. Recommended technique for VSE is either direct or indirect; and for PE and PVS is direct. Key words:Polyvinyl siloxane, polyether, vinyl siloxanether, direct technique, indirect technique, All-on-4, coordinate measuring machine. PMID:29670733

The extrinsic affective Simon task as an instrument for indirect assessment of prejudice

NARCIS (Netherlands)

Degner, J.; Wentura, D.

2008-01-01

We report one study that explored the applicability of the Extrinsic Affective Simon Task (EAST) as an indirect measure of prejudice. The EAST detected known differences in reactions revealing that a Turkish outgroup was spontaneously evaluated more negatively than the German ingroup. More

Direct versus Indirect Explicit Methods of Enhancing EFL Students' English Grammatical Competence: A Concept Checking-Based Consciousness-Raising Tasks Model

Science.gov (United States)

Dang, Trang Thi Doan; Nguyen, Huong Thu

2013-01-01

Two approaches to grammar instruction are often discussed in the ESL literature: direct explicit grammar instruction (DEGI) (deduction) and indirect explicit grammar instruction (IEGI) (induction). This study aims to explore the effects of indirect explicit grammar instruction on EFL learners' mastery of English tenses. Ninety-four…

Putting it to the test : alternative exploration techniques seek recognition

Energy Technology Data Exchange (ETDEWEB)

Cope, G.

2005-06-01

In the past, remote sensing techniques such as magnetic surveying, geochemical sampling and radiometric surveys, were efficient in hard rock mining exploration but were limited in hydrocarbon detection due to problems such as diurnal and weather variations. This article discussed some of the recent advances in technology that have been developed to overcome many of the drawbacks of older systems. Two Calgary-based companies are currently offering innovative and viable exploration alternatives. The Gore-Sorber module is the most accurate and comprehensive surface geochemical sampling technology currently available to the oil and gas industry. The testing module consists of 2 portions of expanded polytetrafluoroethylene polymer material sealed into a GORE-TEX sheath to prevent water and particle contamination. The module is then inserted into a shallow hole to a depth of 50 centimetres and left there for up to 2 weeks. The sample position is marked and surveyed. Over the course of the 2 weeks, volatile and semi-volatile soil gases in the C2-C15 range are absorbed into the material. The modules are analysed in mass spectrometers and gas chromatographs to determine zone and phase information. Advantages of the system include a reduction in soil contamination; the elimination of day-to-day fluctuations; and the fact that lab analysis allows for higher sensitivity. Costs are approximately $60,000 to $70,000 for an area of 16 square kilometres. Disadvantages include the inability to define the amount of hydrocarbons in place or their depth and the fact that proper field operation and collection of data by trained personnel is critical to the analysis process. The technique has been gaining in popularity in Canada as more exploration is directed towards environmentally sensitive frontier areas. Radiometric surveys record the gamma ray emissions of potassium, uranium and thorium as they decay radioactively. As hydrocarbons leak to the surface, they cause geochemical changes

Indirect taxation in the European Union

OpenAIRE

Ene, Sebastian; Micuda, Dan

2007-01-01

Indirect taxes are levied on the production and consumption of goods and services. They influence the retail price, and hence affect patterns of trade and consumption. Indirect taxes are ultimately paid by the final consumer. Sales and turnover taxes, excise duties and tariffs are the basic indirect taxes. In contrast with direct taxes, indirect taxes are seldom progressive. The principles for the levying of these taxes will be considered before the analysis of indirect taxes.

Factors influencing indirect speech and language therapy interventions for adults with learning disabilities: the perceptions of carers and therapists.

Science.gov (United States)

Graves, Judy

2007-03-01

The working context for speech and language therapists (SLTs) delivering interventions to adults who have a learning disability has changed following the reorganization of care provision from hospitals to the community. Consequently, SLTs often deliver their care within a social model of disability through indirect intervention in collaboration with carers. However, there has been little research into how this approach works in practice. To gain insight into the working context by identifying the key factors that influence indirect SLT interventions as perceived by SLTs and by paid carers from a range of service providers. To explore the implications of the results for the delivery of indirect SLT interventions and provide direction for further research. Semi-structured interviews were used to collect data from an opportunistic sample of five SLTs working in Community Learning Disability Teams (CLDTs) and 12 carers from residential and day care services who had had experience of working with SLTs. The data were analysed inductively using a grounded theory framework. Two broad themes emerged for SLTs: roles and expectations, and changing carer behaviour through training. The key themes for carers were roles and values, awareness of communication needs, and motivation and opportunity to implement interventions. Four broad factors are suggested as having the potential to influence indirect interventions: diversity in the working context; possible conflict between the guiding values of SLTs and carers, particularly residential carers; collaboration and support for implementation; and SLT doubts about the effectiveness of formal carer communication training. The results add to the evidence that the delivery of indirect speech and language therapy interventions to people with learning disabilities is a complex activity demanding specialist skills from SLTs. The findings suggest that these should include expertise in professional collaborative and relational skills, and

Nuclear techniques in oil and gas exploration and production

International Nuclear Information System (INIS)

Caldwell, R.L.; Mills, W.R. Jr.; Orr, W.L.; Allen, L.S.

1977-01-01

A review is given of some of the most significant new developments that have occurred during the past three years in the area of nuclear techniques applied to the exploration for and production of oil and gas deposits. Experimental and theoretical studies have been carried out aimed at improving pulsed neutron logging tools and upgrading interpretation of data from such tools. Pulsed neutron borehole generators and gamma-ray spectroscopy have been combined in carbon/oxygen logging to provide a means of determining formation oil saturation in cased holes that is independent of water salinity. Use of pulsed neutron logs in the log-inject-log technique has been tested and evaluated in several field studies. The combination of a gamma-gamma density log and a borehole gravimeter has been used to detect economically important gas accumulations at distances from a borehole that are well beyond the depth of investigation of conventional logging techniques. The depths of investigation of several commercial nuclear logging tools have been studied in laboratory investigations. Possible geological applications of natural gamma-ray spectral logs have been investigated through the study of large sample suites and in specific field applications. The extensive use of digital recording of logging data and well-site analysis by minicomputer are expected to have a significant influence on future logging programmes and logging sonde designs. The present status of stable isotope geochemistry and radioactive tracer surveys is reviewed. (author)

Direct and Indirect Benefits Reported by Users of Transcutaneous Electrical Nerve Stimulation for Chronic Musculoskeletal Pain: Qualitative Exploration Using Patient Interviews.

Science.gov (United States)

Gladwell, Peter William; Badlan, Kathryn; Cramp, Fiona; Palmer, Shea

2015-11-01

There is no consensus regarding the effectiveness of transcutaneous electrical nerve stimulation (TENS) for management of chronic musculoskeletal pain or chronic low back pain. A recent review of previous trial methodology identified significant problems with low treatment fidelity. There is little information available to guide selection of patient-reported outcome measures appropriate for TENS evaluation. The purpose of this study was to explore the experiences of patients at a secondary care pain clinic who successfully used TENS to help manage chronic musculoskeletal pain. These key informants were selected because they had the potential to generate knowledge that could inform research design and clinical practice. A qualitative method using individual semistructured interviews with open questions was selected for its capacity to generate rich data. A mini focus group informed the development of a discussion guide for semistructured interviews with 9 patients (6 women, 3 men). Thematic analysis was used as the primary data analysis method, and this analysis was enhanced by a case-level analysis of the context and processes of TENS use of each individual. Data analysis indicated that distraction from pain and a reduction in the sensations associated with muscle tension or spasm should be considered as separate outcomes from pain relief. These direct benefits led to a wide range of indirect benefits dependent on patient decision making, including medication reduction, enhanced function, psychological benefits, and enhanced ability to rest. The findings indicate that evaluating TENS using a unidimensional pain scale is likely to overlook potential benefits. The complex pattern of TENS usage, as well as multiple direct and indirect outcomes, indicates that TENS could be considered as a complex intervention. © 2015 American Physical Therapy Association.

Improvising with Material in the Higher Education Dance Technique Class: Exploration and Ownership

Science.gov (United States)

Rimmer, Rachel

2013-01-01

In this article the author, Rachel Rimmer, explores how improvisation can facilitate skills that are transferable to other areas of dance practice, enabling different areas of study to complement each other. The experimental forum of improvisation as an alternative method of learning technique is considered, contemplating the value of this…

Recent developments and evaluation of selected geochemical techniques applied to uranium exploration

International Nuclear Information System (INIS)

Wenrich-Verbeek, K.J.; Cadigan, R.A.; Felmlee, J.K.; Reimer, G.M.; Spirakis, C.S.

1976-01-01

Various geochemical techniques for uranium exploration are currently under study by the geochemical techniques team of the Branch of Uranium and Thorium Resources, US Geological Survey. Radium-226 and its parent uranium-238 occur in mineral spring water largely independently of the geochemistry of the solutions and thus are potential indicators of uranium in source rocks. Many radioactive springs, hot or cold, are believed to be related to hydrothermal systems which contain uranium at depth. Radium, when present in the water, is co-precipitated in iron and/or manganese oxides and hydroxides or in barium sulphate associated with calcium carbonate spring deposits. Studies of surface water samples have resulted in improved standardized sample treatment and collection procedures. Stream discharge has been shown to have a significant effect on uranium concentration, while conductivity shows promise as a ''pathfinder'' for uranium. Turbid samples behave differently and consequently must be treated with more caution than samples from clear streams. Both water and stream sediments should be sampled concurrently, as anomalous uranium concentrations may occur in only one of these media and would be overlooked if only one, the wrong one, were analysed. The fission-track technique has been applied to uranium determinations in the above water studies. The advantages of the designed sample collecting system are that only a small quantity, typically one drop, of water is required and sample manipulation is minimized, thereby reducing contamination risks. The fission-track analytical technique is effective at the uranium concentration levels commonly found in natural waters (5.0-0.01 μg/litre). Landsat data were used to detect alteration associated with uranium deposits. Altered areas were detected but were not uniquely defined. Nevertheless, computer processing of Landsat data did suggest a smaller size target for further evaluation and thus is useful as an exploration tool

NEEMO 21: Tools, Techniques, Technologies and Training for Science Exploration

Science.gov (United States)

Graff, T.; Young, K.; Coan, D.; Merselis, D.; Bellantuono, A.; Dougan, K.; Rodriguez-Lanetty, M.; Nedimyer, K.; Chappell, S.; Beaton, K.;

Impact of Direct and Indirect Tax on the Nigerian Economic Growth

Directory of Open Access Journals (Sweden)

Oyebisi Mary Ogundana

2017-11-01

Full Text Available This research examined the direct and indirect impact of taxation on the Nigerian economic growth. This research centered on two major objectives by focusing on the trend of direct and indirect tax and the impact of the Nigerian tax system on the growth of the economy.  The research adopted the descriptive research design.  The secondary source of data was also engaged as this data was from CBN statistical bulletin and the annual reports from 1994-2013. The research also used the ordinary least square regression technique. With the use of E-views 7.1 to analyze the data, the first objective was achieved by using graphical analysis while the second objective used ordinary least square regression analysis. The results reveal that the direct and indirect tax have a positive impact on the economy of Nigeria. Therefore, it is recommended that government should take advantage of taxation and promote tax system in Nigeria.

Getting the most from your curves: Exploring and reporting data using informative graphical techniques

Directory of Open Access Journals (Sweden)

Masaki Matsunaga

2009-09-01

Full Text Available Most psychological research employs tables to report descriptive and inferential statistics. Unfortunately, those tables often misrepresent critical information on the shape and variability of the data’s distribution. In addition, certain information such as the modality and score probability density is hard to report succinctly in tables and, indeed, not reported typically in published research. This paper discusses the importance of using graphical techniques not only to explore data but also to report it effectively. In so doing, the role of exploratory data analysis in detecting Type I and Type II errors is considered. A small data set resembling a Type II error is simulated to demonstrate this procedure, using a conventional parametric test. A potential analysis routine to explore data is also presented. The paper proposes that essential summary statistics and information about the shape and variability of data should be reported via graphical techniques.

Customized biomimetic scaffolds created by indirect three-dimensional printing for tissue engineering

International Nuclear Information System (INIS)

Lee, Ju-Yeon; Choi, Bogyu; Wu, Benjamin; Lee, Min

2013-01-01

Three-dimensional printing (3DP) is a rapid prototyping technique that can create complex 3D structures by inkjet printing of a liquid binder onto powder biomaterials for tissue engineering scaffolds. Direct fabrication of scaffolds from 3DP, however, imposes a limitation on material choices by manufacturing processes. In this study, we report an indirect 3DP approach wherein a positive replica of desired shapes was printed using gelatin particles, and the final scaffold was directly produced from the printed mold. To create patient-specific scaffolds that match precisely to a patient's external contours, we integrated our indirect 3DP technique with imaging technologies and successfully created custom scaffolds mimicking human mandibular condyle using polycaprolactone and chitosan for potential osteochondral tissue engineering. To test the ability of the technique to precisely control the internal morphology of the scaffolds, we created orthogonal interconnected channels within the scaffolds using computer-aided-design models. Because very few biomaterials are truly osteoinductive, we modified inert 3D printed materials with bioactive apatite coating. The feasibility of these scaffolds to support cell growth was investigated using bone marrow stromal cells (BMSC). The BMSCs showed good viability in the scaffolds, and the apatite coating further enhanced cellular spreading and proliferation. This technique may be valuable for complex scaffold fabrication. (paper)

Risk measurement for oil and gas exploration: the marriage of geological and financial techniques

Energy Technology Data Exchange (ETDEWEB)

Stauffer, T.

2002-09-01

A method is presented for fully risking projects, such as exploration ventures or the acquisition of undeveloped reserves. The expected value of an exploration project overstates the 'value', because it does not reflect the uncertainty in the project, as measured by its variance or standard deviation. if the expected value is calculable, then the risk-adjusted value (RAV) can also be calculated. The RAV depends additionally upon the size of the exploration budget, compared with the project, and also upon the 'price of risk'. That price is incorporated from the finance literature. The technique permits answering three related questions: 1) the risk-adjusted rate of return for a given project; 2) the risk-adjusted value of that project; or 3) the risk premium appropriate for a particular project, given the size of the firm's exploration budget. (author)

Drilling techniques for mineral exploration (AMD Training Course Handbook. Vol. 1. 1992)

International Nuclear Information System (INIS)

Singh, Rajendra

1992-01-01

A training course on drilling techniques for mineral exploration was organised between 20 January to 7 February 1992 exclusively for drilling engineers of Atomic Minerals Division (AMD) of the Department of Atomic Energy. The objective was to give the engineers training in theoretical as well as practical aspects of drilling and resource management. The lectures delivered by the faculty members are included in this book. (M.G.B.)

Sensitivity analysis for direct and indirect effects in the presence of exposure-induced mediator-outcome confounders

Science.gov (United States)

Chiba, Yasutaka

2014-01-01

Questions of mediation are often of interest in reasoning about mechanisms, and methods have been developed to address these questions. However, these methods make strong assumptions about the absence of confounding. Even if exposure is randomized, there may be mediator-outcome confounding variables. Inference about direct and indirect effects is particularly challenging if these mediator-outcome confounders are affected by the exposure because in this case these effects are not identified irrespective of whether data is available on these exposure-induced mediator-outcome confounders. In this paper, we provide a sensitivity analysis technique for natural direct and indirect effects that is applicable even if there are mediator-outcome confounders affected by the exposure. We give techniques for both the difference and risk ratio scales and compare the technique to other possible approaches. PMID:25580387

Can we infer external effects from a study of the Irish indirect tax system?

OpenAIRE

Madden, David (David Patrick)

1992-01-01

This paper estimates implied external effects for the Irish indirect tax system for the year 1987. The study uses the inverse optimum technique of Christiansen and Jansen (1978) which estimates implied external effects, given the assumption that the economy is at an optimum with regard to the indirect tax system. External effects are estimated for three goods: tobacco, alcohol and petrol and in all cases the estimated external effects are of the expected sign. The paper also estimates the imp...

Local viscoelastic response of direct and indirect dental restorative composites measured by AFM.

Science.gov (United States)

Grattarola, Laura; Derchi, Giacomo; Diaspro, Alberto; Gambaro, Carla; Salerno, Marco

2018-06-08

We investigated the viscoelastic response of direct and indirect dental restorative composites by the novel technique of AM-FM atomic force microscopy. We selected four composites for direct restorations (Adonis, Optifil, EPH, CME) and three composites for indirect restorations (Gradia, Estenia, Signum). Scanning electron microscopy with micro-analysis was also used to support the results. The mean storage modulus of all composites was in the range of 10.2-15.2 GPa. EPH was the stiffest (pcomposites but Adonis and Estenia), while no significant difference was observed between direct and indirect group (p≥0.05). For the loss tangent, Gradia had the highest value (~0.3), different (pcomposites showed higher loss tangent (pcomposites. All composites exhibited minor contrast at the edge of fillers, showing that these are pre-polymerized, as confirmed by EDS.

Use of nuclear techniques for coal analysis in exploration, mining and processing

International Nuclear Information System (INIS)

Clayton, C.G.; Wormald, M.R.

1982-01-01

Nuclear techniques have a long history of application in the coal industry, during exploration and especially during coal preparation, for the measurement of ash content. The preferred techniques are based on X- and gamma-ray scattering and borehole logging, and on-line equipment incorporating these techniques are now in world-wide routine use. However, gamma-ray techniques are mainly restricted to density measurement and X-ray techniques are principally used for ash determinations. They have a limited range and when used on-line some size reduction of the coal is usually required and a full elemental analysis is not possible. In particular, X- and gamma-ray techniques are insensitive to the principal elements in the combustible component and to many of the important elements in the mineral fraction. Neutron techniques on the other hand have a range which is compatible with on-line requirements and all elements in the combustible component and virtually all elements in the mineral component can be observed. A complete elemental analysis of coal then allows the ash content and the calorific value to be determined on-line. This paper surveys the various nuclear techniques now in use and gives particular attention to the present state of development of neutron methods and to their advantages and limitations. Although it is shown that considerable further development and operational experience are still required, equipment now being introduced has a performance which matches many of the identified requirements and an early improvement in specification can be anticipated

An Empirical Analysis of Indirect Network Effects in the Home Video Game Market

OpenAIRE

James E. Prieger; Wei-Min Hu

2006-01-01

We explore the indirect network effect in the market for home video games. We examine the video game console makers’ strategic choice between increasing demand by lowering console price and by encouraging the growth of software variety. We also explore the existence of an applications barrier to entry in the console market, and find that there is little evidence for such a barrier. Finally, we assess the applicability of the model to out-of-sample situations, to look at whether our model and ...

Accuracy of different abutment level impression techniques in All-On-4 dental implants

Directory of Open Access Journals (Sweden)

Marzieh Alikhasi

2012-01-01

Full Text Available Background and Aims: Passive fit of prosthetic frameworks is a major concern in implant dentistry. Impression technique is one of the several variables that may affect the outcome of dental implants. The purpose of this study was to compare the three dimensional accuracy of direct and indirect abutment level implant impressions ofALL-ON-4 treatment plan.Materials and Methods: A reference acrylic resin model with four Branemark fixtures was made according to All-On-4 treatment plan. Multiunit abutments were screwed into the fixtures and two special trays were made for direct and indirect impression techniques. Ten direct and ten indirect impression techniques with respective impression transfers were made. Impressions were poured with stone and the positional accuracy of the abutment analogues in each dimension of x, y, and z axes and also angular displacement (Δθ were evaluated using a Coordinate Measuring Machine (CMM. Data were analyzed using T- test.Results: The results showed that direct impression technique was significantly more accurate than indirect technique (P<0.001.Conclusion: The results showed that the accuracy of direct impression technique was significantly more than that of indirect technique in Δθ and Δr coordinate and also Δx, Δy, Δz.

Glances on uranium. Tome 2. Exploration, production

International Nuclear Information System (INIS)

Valsardieu, C.

1997-01-01

This book is an homage to all participants of uranium prospecting and mining exploitation who have contributed to satisfy the nuclear energy needs during the last 50 years. The first chapter describes the economical, administrative and environmental constraints of uranium mining projects. The second chapter describes the different steps of the exploration (permits, inventory, mineralisation, quality, resource estimation, quantifying), the direct and indirect exploratory techniques and methods (radiometry, geochemistry, drillings and well logging, mapping, tele-detection, geophysical surveys..) and the exploration costs. The third chapter deals with the legal, administrative, technical, socio-economical and financial aspects which must be taken into account in the risk evaluation of a mining project. Chapter 4 concerns the start up of the project while the development and production methods are detailed in chapter 5 (opencast and underground mining, in-situ lixiviation, ore processing, chemical extraction etc.). The last chapter is devoted to the environmental aspects of uranium mining: legal aspects, nuisances, dusts, contamination, the case of in-situ lixiviation, the rehabilitation of sites. (J.S.)

Indirect Self-Destructiveness in Women who Experience Domestic Violence.

Science.gov (United States)

Tsirigotis, Konstantinos; Łuczak, Joanna

2018-01-02

Lives of people experiencing domestic or/and intimate partner violence abound in many unpleasant events and physical and psychological suffering, which affects their psychosocial functioning. The aim of this study was to explore indirect self-destructiveness as a generalised behavioural tendency and its manifestations in women experiencing domestic violence. The "Chronic Self-Destructiveness Scale" (CS-DS) was used to study two groups of women: 52 women aged 30-65 years (mean age: 40.15) using assistance of the Crisis Intervention Centre due to experienced domestic violence (V group) and 150 well-matched women not experiencing domestic violence (NV group). Women suffering domestic violence (V) obtained significantly higher scores than women not experiencing domestic violence (NV) for both the general index and a majority of CS-DS subscales; it was only for the A1 (Transgression and Risk) subscale that they achieved somewhat lower scores. Correlation coefficients between particular CS-DS subscales in the V group were higher than in the NV group; there were also certain differences in coefficients between the groups. Subscale factor analysis results were different too: only one factor was isolated in the V group while two were distinguished in the NV group. It can be inferred from the results that the intensity of indirect self-destructiveness as a generalised behavioural tendency as well as of most its categories was higher in women experiencing domestic violence. Tendencies and categories of indirectly self-destructive behaviours in women suffering domestic violence were more closely connected with one another, and the internal coherence of indirect self-destructiveness in those women might also be higher.

Comment traduire en japonais les styles indirect et indirect libre de Madame Bovary ?

Directory of Open Access Journals (Sweden)

Hisaki Sawasaki

2012-03-01

Full Text Available Parmi les difficultés rencontrées lors de la traduction des textes littéraires occidentaux, en japonais, nous examinons le problème des styles indirect et indirect libre. Pour cela, en effectuant une petite mise au point grammaticale, nous comparons sept traductions de Madame Bovary de Gustave Flaubert, dont les dates de parution s’étendent sur une cinquantaine d’années. Cette période s’apparente, de notre point de vue, à un long itinéraire pour assimiler la notion occidentale des styles direct et indirect, tout en la conciliant avec les particularités du japonais. D’un autre côté, ce travail acharné des traducteurs a influencé quelque peu la langue japonaise. On trouve dans l’annexe tous les textes en japonais examinés.We will examine the difficulties met when translating Western literary texts in Japanese, in particular the problem of indirect and free indirect styles. We will define the grammatical issue and compare seven translations of Madame Bovary, published over a fifty year period. This time can be likened to a long path taken to digest the Western notion of direct and indirect styles, while reconciling it with Japanese language characteristics. On the other hand the translators’ relentless work has somewhat influenced the Japanese language. The annex will present all the Japanese texts examined.

Direct versus indirect revascularization procedures for moyamoya disease: a comparative effectiveness study.

Science.gov (United States)

Macyszyn, Luke; Attiah, Mark; Ma, Tracy S; Ali, Zarina; Faught, Ryan; Hossain, Alisha; Man, Karen; Patel, Hiren; Sobota, Rosanna; Zager, Eric L; Stein, Sherman C

2017-05-01

OBJECTIVE Moyamoya disease (MMD) is a chronic cerebrovascular disease that can lead to devastating neurological outcomes. Surgical intervention is the definitive treatment, with direct, indirect, and combined revascularization procedures currently employed by surgeons. The optimal surgical approach, however, remains unclear. In this decision analysis, the authors compared the effectiveness of revascularization procedures in both adult and pediatric patients with MMD. METHODS A comprehensive literature search was performed for studies of MMD. Using complication and success rates from the literature, the authors constructed a decision analysis model for treatment using a direct and indirect revascularization technique. Utility values for the various outcomes and complications were extracted from the literature examining preferences in similar clinical conditions. Sensitivity analysis was performed. RESULTS A structured literature search yielded 33 studies involving 4197 cases. Cases were divided into adult and pediatric populations. These were further subdivided into 3 different treatment groups: indirect, direct, and combined revascularization procedures. In the pediatric population at 5- and 10-year follow-up, there was no significant difference between indirect and combination procedures, but both were superior to direct revascularization. In adults at 4-year follow-up, indirect was superior to direct revascularization. CONCLUSIONS In the absence of factors that dictate a specific approach, the present decision analysis suggests that direct revascularization procedures are inferior in terms of quality-adjusted life years in both adults at 4 years and children at 5 and 10 years postoperatively, respectively. These findings were statistically significant (p indirect and combination procedures may offer optimal results at long-term follow-up.

Language shifts in free indirect discourse

NARCIS (Netherlands)

Maier, Emar

Free indirect discourse is a way of reporting what a protagonist thinks or says that is distinct from both direct and indirect discourse. In particular, while pronouns and tenses are presented from the narrator's perspective, as in indirect discourse, other indexical and expressive elements reflect

Directe en indirecte werknemersparticipatie in Europa

NARCIS (Netherlands)

van Houten, Gijs; Akkerman, Agnes; Sluiter, Roderick; Jansen, Giedo; Vermeylen, Greet

2016-01-01

This study looks at different forms of direct and indirect employee participation in the EU. The research questions are: (1) which forms of direct and indirect employee participation can we distinguish?; (2) to what extent do forms of direct and indirect employee participation coincide within

Uranium exploration in Australia

International Nuclear Information System (INIS)

Battey, G.C.; Hawkins, B.W.

1977-01-01

As a result of exploration which recommenced in 1966 Australia's uranium reserves increased from 6,200 tonnes in 1967 to 227,000 tonnes uranium by June 1976. Most discoveries in the early 1950's were made by prospectors. The increase in reserves during the past decade is the result of exploration by companies utilising improved technology in areas selected as geologically favourable. These reserves were established at relatively low cost. In the Alligator Rivers Uranium Province the ''vein'' type deposits at Jabiluka, Ranger, Koongarra and Nabarlek contain 17% of the world's reserves. Most of these discoveries resulted from the investigation of airborne radiometric anomalies but cover over the prospective host rocks will necessitate the future use of costlier and more indirect exploration techniques. There was exploration for sandstone type uranium deposits in most of Australia's sedimentary basins. The greatest success was achieved in the Lake Frome Basin in South Australia. Other deposits were found in the Ngalia and Amadeus Basins in Central Australia and in the Westmoreland area, N.W. Queensland. A major uranium deposit was found in an unusual environment at Yeelirrie, Western Australia where carnotite occurs in a caliche and clay host which fills a shallow, ancient drainage channel. Although caliche occurrences are relatively widespread on the Precambrian shield no other economic deposit has been found. Recent discoveries in the Georgetown area of Queensland indicate the presence of another uranium province but it is too early to assess its potential. The ore occurs in clastic sediments at the base of a volcanic sequence overlying a Precambrian basement. Several companies which have established large uranium reserves have a number of additional attractive prospects. Exploration activity in Australia in 1975 was at a lower level than in previous years, but the potential for discovering further deposits is considered to be high

Stem cell monitoring with a direct or indirect labeling method

Energy Technology Data Exchange (ETDEWEB)

Kim, Min Hwan; Lee, Yong Jin [Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul (Korea, Republic of)

2016-12-15

The molecular imaging techniques allow monitoring of the transplanted cells in the same individuals over time, from early localization to the survival, migration, and differentiation. Generally, there are two methods of stem cell labeling: direct and indirect labeling methods. The direct labeling method introduces a labeling agent into the cell, which is stably incorporated or attached to the cells prior to transplantation. Direct labeling of cells with radionuclides is a simple method with relatively fewer adverse events related to genetic responses. However, it can only allow short-term distribution of transplanted cells because of the decreasing imaging signal with radiodecay, according to the physical half-lives, or the signal becomes more diffuse with cell division and dispersion. The indirect labeling method is based on the expression of a reporter gene transduced into the cell before transplantation, which is then visualized upon the injection of an appropriate probe or substrate. In this review, various imaging strategies to monitor the survival and behavior change of transplanted stem cells are covered. Taking these new approaches together, the direct and indirect labeling methods may provide new insights on the roles of in vivo stem cell monitoring, from bench to bedside.

The logic of indirect speech

Science.gov (United States)

Pinker, Steven; Nowak, Martin A.; Lee, James J.

2008-01-01

When people speak, they often insinuate their intent indirectly rather than stating it as a bald proposition. Examples include sexual come-ons, veiled threats, polite requests, and concealed bribes. We propose a three-part theory of indirect speech, based on the idea that human communication involves a mixture of cooperation and conflict. First, indirect requests allow for plausible deniability, in which a cooperative listener can accept the request, but an uncooperative one cannot react adversarially to it. This intuition is supported by a game-theoretic model that predicts the costs and benefits to a speaker of direct and indirect requests. Second, language has two functions: to convey information and to negotiate the type of relationship holding between speaker and hearer (in particular, dominance, communality, or reciprocity). The emotional costs of a mismatch in the assumed relationship type can create a need for plausible deniability and, thereby, select for indirectness even when there are no tangible costs. Third, people perceive language as a digital medium, which allows a sentence to generate common knowledge, to propagate a message with high fidelity, and to serve as a reference point in coordination games. This feature makes an indirect request qualitatively different from a direct one even when the speaker and listener can infer each other's intentions with high confidence. PMID:18199841

Indirect Cost Reimbursement: An Industrial View.

Science.gov (United States)

Bolton, Robert

1987-01-01

The meaning of indirect costs in an industrial environment is discussed. Other factors considered are corporate policies; nature of work being supported; the uniqueness of the work; who is doing the negotiating for industry; and indirect rates. Suggestions are offered for approaches to indirect cost reimbursement. (Author/MLW)

The electronic origin of shear-induced direct to indirect gap transition and anisotropy diminution in phosphorene.

Science.gov (United States)

Sa, Baisheng; Li, Yan-Ling; Sun, Zhimei; Qi, Jingshan; Wen, Cuilian; Wu, Bo

2015-05-29

Artificial monolayer black phosphorus, so-called phosphorene, has attracted global interest with its distinguished anisotropic, optoelectronic, and electronic properties. Here, we unraveled the shear-induced direct-to-indirect gap transition and anisotropy diminution in phosphorene based on first-principles calculations. Lattice dynamic analysis demonstrates that phosphorene can sustain up to 10% applied shear strain. The bandgap of phosphorene experiences a direct-to- indirect transition when 5% shear strain is applied. The electronic origin of the direct-to-indirect gap transition from 1.54 eV at ambient conditions to 1.22 eV at 10% shear strain for phosphorene is explored. In addition, the anisotropy diminution in phosphorene is discussed by calculating the maximum sound velocities, effective mass, and decomposed charge density, which signals the undesired shear-induced direct-to-indirect gap transition in applications of phosphorene for electronics and optoelectronics. On the other hand, the shear-induced electronic anisotropy properties suggest that phosphorene can be applied as the switcher in nanoelectronic applications.

Who exhibits more energy-saving behavior in direct and indirect ways in china? The role of psychological factors and socio-demographics

International Nuclear Information System (INIS)

Yang, Shu; Zhang, Yanbing; Zhao, Dingtao

2016-01-01

This research explores the possibilities for further energy saving in households in the Chinese context by conducting of a survey on energy curtailment behaviors. We examine how people's demographic characteristics and psychological factors affect their direct and indirect energy curtailment behaviors at home, as well as the different effects of these antecedents. Results suggest that people with high sense of environmental responsibility and curtailment attitude are more likely to engage in both direct and indirect energy curtailment actions. Generally, indirect energy curtailment behavior is more strongly related to psychological and socio-demographic factors than direct behavior, and these socio-demographic factors vary for direct and indirect behaviors. Interesting patterns emerged with respect to gender, age, family structure, family income, and level of education. Results indicate that strengthening publicity and education to increase environmental awareness among Chinese urban residents would be effective in reducing household energy consumption, especially when the said measures target a specific population and specific behaviors. - Highlights: •A survey is used to explore Chinese urban residents' energy curtailment behaviors. •Make a distinction between direct and indirect energy curtailment behaviors. •Effects of demographic and psychological variables are different on two behaviors. •Policy should target at specific behaviors and specific population.

Indirect detection of dark matter with γ rays.

Science.gov (United States)

Funk, Stefan

2015-10-06

The details of what constitutes the majority of the mass that makes up dark matter in the Universe remains one of the prime puzzles of cosmology and particle physics today-80 y after the first observational indications. Today, it is widely accepted that dark matter exists and that it is very likely composed of elementary particles, which are weakly interacting and massive [weakly interacting massive particles (WIMPs)]. As important as dark matter is in our understanding of cosmology, the detection of these particles has thus far been elusive. Their primary properties such as mass and interaction cross sections are still unknown. Indirect detection searches for the products of WIMP annihilation or decay. This is generally done through observations of γ-ray photons or cosmic rays. Instruments such as the Fermi large-area telescope, high-energy stereoscopic system, major atmospheric gamma-ray imaging Cherenkov, and very energetic radiation imaging telescope array, combined with the future Cherenkov telescope array, will provide important complementarity to other search techniques. Given the expected sensitivities of all search techniques, we are at a stage where the WIMP scenario is facing stringent tests, and it can be expected that WIMPs will be either be detected or the scenario will be so severely constrained that it will have to be rethought. In this sense, we are on the threshold of discovery. In this article, I will give a general overview of the current status and future expectations for indirect searches of dark matter (WIMP) particles.

Direct and Indirect Harassment Experiences and Burnout among Academic Faculty in Japan.

Science.gov (United States)

Takeuchi, Masumi; Nomura, Kyoko; Horie, Saki; Okinaga, Hiroko; Perumalswami, Chithra R; Jagsi, Reshma

2018-05-01

The purpose of this study is three-fold: (1) to compare harassment (sexual, gender, and academic harassment both directly and indirectly experienced - i.e. "directly harassed" and "have seen or heard of someone who experienced harassment", respectively) experienced by males and females, (2) to investigate whether such experiences correlate with burnout, and (3) to explore whether social support might mitigate any such relationship between harassment and burnout. This cross-sectional study was conducted at a private university in Japan in February 2014 and is based on a work-life balance survey obtained from 330 academic faculty members. We investigated the association between each of the six subcategories of harassment (direct and indirect forms of each of the three types) and burnout using general linear regression models; we then evaluated interactions between harassment and social support in these models. The prevalence of direct and indirect experiences of harassment was higher in females than in males for all three types of harassment. Males showed higher burnout scores if they had direct experiences of harassment. There were significant interactions between social support and the direct experience of harassment; high social support mitigated the effect size of direct harassment on burnout among males. Females showed higher burnout scores if they had indirect experiences of harassment. However, the same buffering effect of social support on burnout as observed in males was not observed in females. Direct harassment experiences increased the risk of burnout in males, and indirect harassment experiences increased burnout in females.

Indirect Calorimetry in Mechanically Ventilated Patients

DEFF Research Database (Denmark)

Allingstrup, Matilde Jo; Kondrup, Jens; Perner, Anders

2017-01-01

Background and Aims: The 2 currently available indirect calorimeters, CCM Express Indirect Calorimeter (MedGraphics, St Paul, MN) and Quark RMR ICU Indirect Calorimeter (COSMED, Rome, Italy), have not been validated against a gold standard in mechanically ventilated patients. Our aim was to do so...... using a gold-standard, modified Tissot bell-spirometer method in mechanically ventilated patients who were hemodynamically, respiratory, and metabolically stable. Methods: We studied 30 patients undergoing general anesthesia and major gynecological surgery. We measured oxygen consumption ((Formula...... of 77 (167) with limits of agreement −249 to 404 kcal/d. Conclusions: The QUARK RMR ICU Indirect Calorimeter compared better with the gold standard for values of (Formula presented.) O2 and REE than did the CCM Express Indirect Calorimeter in mechanically ventilated patients who were circulatory...

The Complexity of Indirect Translation

DEFF Research Database (Denmark)

Wenjie, L. I.

2017-01-01

its complex nature, and thus determined that many facets of ITr remain to be studied. The present article will try to encompass the complexity of ITr by looking into the reasons for translating indirectly, the challenge of finding out mediating texts (MTs), indirectness in both translation...... of which have been translated and interpreted indirectly through major languages like English, will be employed as examples. Hopefully, this study will offer more insights into the nature of translation as a social activity and raise further interests in studying translation as a complex phenomenon....

Geophysical Exploration. New site exploration method

Energy Technology Data Exchange (ETDEWEB)

Imai, Tsuneo; Otomo, Hideo; Sakayama, Toshihiko

1988-07-25

Geophysical exploration is used for geologic survey to serve purposes in civil engineering. New methods are being developed inside and outside Japan and are used to serve various purposes. This paper discusses recently developed techniques based on the measurement of seismic waves and electric potential. It also explains seismic tomography, radar tomography, and resistivity tomography which are included in the category of geotomography. At present, effort is being made to apply geophysical exploration technology to problems which were considered to be unsuitable for conventional exploration techniques. When such effort proceeds successfully, it is necessary to develop technology for presenting results quickly and exploration equipment which can work in various conditions. (10 figs, 15 refs)

Understanding and quantifying focused, indirect groundwater recharge from ephemeral streams using water table fluctuations

Science.gov (United States)

Cuthbert, M. O.; Acworth, R. I.; Andersen, M. S.; Larsen, J. R.; McCallum, A. M.; Rau, G. C.; Tellam, J. H.

2016-02-01

Understanding and managing groundwater resources in drylands is a challenging task, but one that is globally important. The dominant process for dryland groundwater recharge is thought to be as focused, indirect recharge from ephemeral stream losses. However, there is a global paucity of data for understanding and quantifying this process and transferable techniques for quantifying groundwater recharge in such contexts are lacking. Here we develop a generalized conceptual model for understanding water table and groundwater head fluctuations due to recharge from episodic events within ephemeral streams. By accounting for the recession characteristics of a groundwater hydrograph, we present a simple but powerful new water table fluctuation approach to quantify focused, indirect recharge over both long term and event time scales. The technique is demonstrated using a new, and globally unparalleled, set of groundwater observations from an ephemeral stream catchment located in NSW, Australia. We find that, following episodic streamflow events down a predominantly dry channel system, groundwater head fluctuations are controlled by pressure redistribution operating at three time scales from vertical flow (days to weeks), transverse flow perpendicular to the stream (weeks to months), and longitudinal flow parallel to the stream (years to decades). In relative terms, indirect recharge decreases almost linearly away from the mountain front, both in discrete monitored events as well as in the long-term average. In absolute terms, the estimated indirect recharge varies from 80 to 30 mm/a with the main uncertainty in these values stemming from uncertainty in the catchment-scale hydraulic properties.

Human cryptosporidiosis: detection of specific antibodies in the serum by an indirect immunofluorescence

Directory of Open Access Journals (Sweden)

Braz Lúcia M.A.

1996-01-01

Full Text Available Cryptosporidium sp., a coccidian parasite usually found in the faeces of cattle, has been recently implicated as an agent of human intestinal disease, mainly in immunocompromised patients. In the study realized, by an indirect immunofluorescence technique, specific immunoglobulins (IgG and IgM have been demonstrated in human serum against Cryptosporidium oocysts. Purified oocysts were used as antigens in the indirect immunofluorecence assay. After analyzing this test in sera from selected groups of patients, the frequency of both specific IgG and IgM of immunocompetent children who were excreting oocysts in their faeces was 62% and in children with negative excretion of oocysts was 20% and 40%, respectively. In adults infected with the human immunodeficiency virus (HIV and who were excreting Cryptosporidium in their stools, the frequency was 57% for IgG but only 2% for IgM. Twenty three percent of immunocompromised adults with not determined excretion of oocysts in their stools had anti-Cryptosporidium IgG in their sera. Children infected with human immunodeficiency virus had no IgM and only 14% had IgG detectable in their sera. The indirect immunoflorescence assay, when used with other parasitological techniques appears to be useful for retrospective population studies and for diagnosis of acute infection. The humoral immune response of HIV positive patients to this protozoan agent needs clarification.

Measurement Properties of Indirect Assessment Methods for Functional Behavioral Assessment: A Review of Research

Science.gov (United States)

Floyd, Randy G.; Phaneuf, Robin L.; Wilczynski, Susan M.

2005-01-01

Indirect assessment instruments used during functional behavioral assessment, such as rating scales, interviews, and self-report instruments, represent the least intrusive techniques for acquiring information about the function of problem behavior. This article provides criteria for examining the measurement properties of these instruments…

Tolerant indirect reciprocity can boost social welfare through solidarity with unconditional cooperators in private monitoring.

Science.gov (United States)

Okada, Isamu; Sasaki, Tatsuya; Nakai, Yutaka

2017-08-29

Indirect reciprocity is an important mechanism for resolving social dilemmas. Previous studies explore several types of assessment rules that are evolutionarily stable for keeping cooperation regimes. However, little is known about the effects of private information on social systems. Most indirect reciprocity studies assume public monitoring in which individuals share a single assessment for each individual. Here, we consider a private monitoring system that loosens such an unnatural assumption. We explore the stable norms in the private system using an individual-based simulation. We have three main findings. First, narrow and unstable cooperation: cooperation in private monitoring becomes unstable and the restricted norms cannot maintain cooperative regimes while they can in public monitoring. Second, stable coexistence of discriminators and unconditional cooperators: under private monitoring, unconditional cooperation can play a role in keeping a high level of cooperation in tolerant norm situations. Finally, Pareto improvement: private monitoring can achieve a higher cooperation rate than does public monitoring.

Principles and characteristics of surface radon and helium techniques used in uranium exploration

International Nuclear Information System (INIS)

Pacer, J.C.; Czarnecki, R.F.

1980-09-01

Studies were carried out to determine the nature of some of the surface radon and helium techniques used for uranium exploration. By performing radon and helium measurements at three sites with differing geology and accessibility, we were able to examine the constraints on the features determined. The sites are the Red Desert in south central Wyoming, Copper Mountain in central Wyoming, and Spokane Mountain in eastern Washington. The radon techniques employed were: zinc sulfide detectors, an ionization chamber, alpha track detectors, thermoluminescence detectors, charcoal canisters, and the partial extraction of lead-210 from soil samples. Helium was measured in soil-gas samples, soil gas from collectors, and soil samples. The ratio helium-4/argon-36 was measured in soil gas

Indirect deformation (strain) measurements and calibrations in Sandia triaxial apparatus for rock testing to 2500C

International Nuclear Information System (INIS)

Wawersik, W.R.

1979-09-01

Indirect procedures for axial and radial strain measurements on rock in triaxial tests to 250 0 C are presented. The description of techniques includes discussions of all calibrations and of the accuracies of measurements. In addition, two examples are given to show how the techniques are implemented in triaxial compression and triaxial extension experiments. 10 figures

Indirect Reciprocity; A Field Experiment.

Science.gov (United States)

van Apeldoorn, Jacobien; Schram, Arthur

2016-01-01

Indirect reciprocity involves cooperative acts towards strangers, either in response to their kindness to third parties (downstream) or after receiving kindness from others oneself (upstream). It is considered to be important for the evolution of cooperative behavior amongst humans. Though it has been widely studied theoretically, the empirical evidence of indirect reciprocity has thus far been limited and based solely on behavior in laboratory experiments. We provide evidence from an online environment where members can repeatedly ask and offer services to each other, free of charge. For the purpose of this study we created several new member profiles, which differ only in terms of their serving history. We then sent out a large number of service requests to different members from all over the world. We observe that a service request is more likely to be rewarded for those with a profile history of offering the service (to third parties) in the past. This provides clear evidence of (downstream) indirect reciprocity. We find no support for upstream indirect reciprocity (in this case, rewarding the service request after having previously received the service from third parties), however. Our evidence of downstream indirect reciprocity cannot be attributed to reputational effects concerning one's trustworthiness as a service user.

Mission Techniques for Exploring Saturn's icy moons Titan and Enceladus

Science.gov (United States)

Reh, Kim; Coustenis, Athena; Lunine, Jonathan; Matson, Dennis; Lebreton, Jean-Pierre; Vargas, Andre; Beauchamp, Pat; Spilker, Tom; Strange, Nathan; Elliott, John

2010-05-01

techniques and to describe risk reduction efforts and recent advances toward enabling such future missions. References [1] NRC Space Studies Board (2003), New Frontiers in the Solar System: An Integrated Exploration Strategy (first Decadal Survey Report), National Academic Press, Washington, DC. [2] Coustenis et al. (2008). Experimental Astronomy, DOI: 10.1007/s10686-008-9103-z. [3] J. Leary, R. Strain, R. Lorenz, J. H. Waite, 2008. Titan Explorer Flagship Mission Study, http://www.lpi.usra.edu/opag/Titan_Explorer_Public_Report.pdf. [4] TSSM Final Report, 3 November 2008, NASA Task Order NMO710851 [5] TSSM NASA/ESA Joint Summary Report, 15 November 2008, NASA Task Order NMO710851

Indirectly cooled large thin superconducting CDF solenoid

International Nuclear Information System (INIS)

Kondo, Kunitaka; Mori, Shigeki; Yoshizaki, Ryozo; Saito, Ryusei; Asano, Katsuhiko.

1985-01-01

The manufacturing technique of the indirectly cooled large thin superconducting solenoid for the collider detector facility (CDF solenoid) has been studied through cooperation of University of Tsukuba and the National Laboratory for High Energy Physics of the Ministry of Education of Japan, and the Fermi National Accelerator Laboratory in the U.S. Fabrication and testing of the solenoid has recently been completed by Hitachi. The CDF solenoid has a large-sized thin structure for meeting the requirement by experiments to be applied. Hitachi has thus developed a variety of new technologies including the design standard, coil cooling method, material selection, and manufacturing technique in accordance with experimental data, which were confirmed in a series of analyses and tests made on various prototypes. The CDF solenoid, built using Hitachi's new technologies, is of the world's top class among equipment of this type. This paper outlines the design criteria for the major components employed in the CDF solenoid and the test results of the solenoid. (author)

Indirect narration : a case study of Conrad's Heart of darkness and Fitzgerald's The Great Gatsby

Directory of Open Access Journals (Sweden)

Majda Šavle

2007-12-01

Full Text Available Joseph Conrad's narrative style bas influenced many writers, including F. Scott Fitzgerald. The objective of my study on verbs used in discourse in Conrad's Heart of Darkness and Fitzgerald's The Great Gatsby was to confirm  the speculation  that besides Conrad's innovative technique of indirect narration there were other techniques (such as careful selection of imagistic detail Fitzgerald learned from Conrad.

Exploring the Earth Using Deep Learning Techniques

Science.gov (United States)

Larraondo, P. R.; Evans, B. J. K.; Antony, J.

2016-12-01

Research using deep neural networks have significantly matured in recent times, and there is now a surge in interest to apply such methods to Earth systems science and the geosciences. When combined with Big Data, we believe there are opportunities for significantly transforming a number of areas relevant to researchers and policy makers. In particular, by using a combination of data from a range of satellite Earth observations as well as computer simulations from climate models and reanalysis, we can gain new insights into the information that is locked within the data. Global geospatial datasets describe a wide range of physical and chemical parameters, which are mostly available using regular grids covering large spatial and temporal extents. This makes them perfect candidates to apply deep learning methods. So far, these techniques have been successfully applied to image analysis through the use of convolutional neural networks. However, this is only one field of interest, and there is potential for many more use cases to be explored. The deep learning algorithms require fast access to large amounts of data in the form of tensors and make intensive use of CPU in order to train its models. The Australian National Computational Infrastructure (NCI) has recently augmented its Raijin 1.2 PFlop supercomputer with hardware accelerators. Together with NCI's 3000 core high performance OpenStack cloud, these computational systems have direct access to NCI's 10+ PBytes of datasets and associated Big Data software technologies (see http://geonetwork.nci.org.au/ and http://nci.org.au/systems-services/national-facility/nerdip/). To effectively use these computing infrastructures requires that both the data and software are organised in a way that readily supports the deep learning software ecosystem. Deep learning software, such as the open source TensorFlow library, has allowed us to demonstrate the possibility of generating geospatial models by combining information from

Application of commercial exploration techniques to site selection and characterization

International Nuclear Information System (INIS)

Brewer, W.A.

1987-01-01

Since 1976 the U.S Department of Energy has conducted intensive geologic studies of the Hanford Nuclear Reservation in south-central Washington. With passage of the Nuclear Waste Policy Act of 1982 the process of search for a geologically suitable waste repository site became more structured, and it has been subject to outside review by the state, affected Indian tribes and other federal agencies, notably the Nuclear Regulatory Commission and the U.S Geological Survey. This paper contrasts the USDOE approach with that of the mining and petroleum industries, highlighting fundamental differences in philosophy and techniques. It is proposed that the principle of ''condemnation,'' which is fundamental in commercial exploration methods, could greatly benefit the USDOE siting program, which by comparison has been slow, costly and not very productive

Comparison of viral RNA electrophoresis and indirect ELISA methods in the diagnosis of human rotavirus infection

International Nuclear Information System (INIS)

Avendano, L.F.; Dubinovsky, S.

1984-01-01

A total of 177 stool samples from Chilean diarrhea patients under two years of age were tested for rotavirus by two methods - the indirect enzyme-linked immunosorbent assay (indirect ELISA) and viral RNA electrophoresis in agarose gels (v RNA EPH). Fifty of the specimens came from patients with acute diarrhea and 127 came from patients with protracted diarrhea. The indirect ELISA testing was performed at the National Institutes of Health in the United States: the electrophoretic testing was carried out in Santiago, Chile by the authors. The electrophoretic method detected rotavirus in 36% of the acute samples and 25% of the samples from protracted cases, while the indirect ELISA method detected rotavirus in higher percentages of samples - 46% and 38%, respectively. These results support the conclusion that v RNA EPH is a less sensitive method for detecting rotavirus than the indirect ELISA. Nevertheless, the former method's high specificity, ease of application, and low cost make it a worthwhile alternative to indirect ELISA. Thus, considering the important role played by rotavirus in infant diarrhea and the need for a diagnostic technique that can be incorporated into the routines of medical center laboratories in developing countries, there is good reason to conclude that v RNA EPH is a useful tool for studying rotavirus diarrhea. (author)

Bacterial adhesion on direct and indirect dental restorative composite resins: An in vitro study on a natural biofilm.

Science.gov (United States)

Derchi, Giacomo; Vano, Michele; Barone, Antonio; Covani, Ugo; Diaspro, Alberto; Salerno, Marco

2017-05-01

Both direct and indirect techniques are used for dental restorations. Which technique should be preferred or whether they are equivalent with respect to bacterial adhesion is unclear. The purpose of this in vitro study was to determine the affinity of bacterial biofilm to dental restorative composite resins placed directly and indirectly. Five direct composite resins for restorations (Venus Diamond, Adonis, Optifil, Enamel Plus HRi, Clearfil Majesty Esthetic) and 3 indirect composite resins (Gradia, Estenia, Signum) were selected. The materials were incubated in unstimulated whole saliva for 1 day. The biofilms grown were collected and their bacterial cells counted. In parallel, the composite resin surface morphology was analyzed with atomic force microscopy. Both bacterial cell count and surface topography parameters were subjected to statistical analysis (α=.05). Indirect composite resins showed significantly lower levels than direct composite resins for bacterial cell adhesion, (Pcomposite resins (P>.05). However, within the indirect composite resins a significantly lower level was found for Gradia than Estenia or Signum (Pcomposite resin roughness and bacterial adhesion when the second and particularly the third-order statistical moments of the composite resin height distributions were considered. Indirect dental restorative composite resins were found to be less prone to biofilm adhesion than direct composite resins. A correlation of bacterial adhesion to surface morphology exists that is described by kurtosis; thus, advanced data analysis is required to discover possible insights into the biologic effects of morphology. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Supersymmetric dark matter: Indirect detection

International Nuclear Information System (INIS)

Bergstroem, L.

2000-01-01

Dark matter detection experiments are improving to the point where they can detect or restrict the primary particle physics candidates for non baryonic dark matter. The methods for detection are usually categorized as direct, i.e., searching for signals caused by passage of dark matter particles in terrestrial detectors, or indirect. Indirect detection methods include searching for antimatter and gamma rays, in particular gamma ray lines, in cosmic rays and high-energy neutrinos from the centre of the Earth or Sun caused by accretion and annihilation of dark matter particles. A review is given of recent progress in indirect detection, both on the theoretical and experimental side

INDIRECT LABOR COSTS AND IMPLICATIONS FOR OVERHEAD ALLOCATION

OpenAIRE

Bea Chiang

2013-01-01

Cost accounting typically allocates indirect labor cost to cost object based on direct labor hours. The allocation process implicitly assumes that indirect labor costs vary proportionally with direct labor hours. The assumption of a linear relationship between indirect and direct labor is particularly suspicious at low production volume levels because there tends to be a fixed component in indirect labor. The linearity assumption is also challenged by recent increasing complexity of indirect ...

Indirectly driven, high convergence inertial confinement fusion implosions

International Nuclear Information System (INIS)

Cable, M.D.; Hatchett, S.P.; Caird, J.A.; Kilkenny, J.D.; Kornblum, H.N.; Lane, S.M.; Laumann, C.; Lerche, R.A.; Murphy, T.J.; Murray, J.; Nelson, M.B.; Phillion, D.W.; Powell, H.; Ress, D.B.

1994-01-01

A series of high convergence indirectly driven implosions has been done with the Nova Laser Fusion facility. These implosions were well characterized by a variety of measurements; computer models are in good agreement. The imploded fuel areal density was measured using a technique based on secondary neutron spectroscopy. At capsule convergences of 24:1, comparable to what is required for the hot spot of ignition scale capsules, these capsules achieved fuel densities of 19 g/cm 3 . Independent measurements of density, burn duration, and ion temperature gave nτθ=1.7±0.9x10 14 keV s/cm 3

Observations of indirect filial cannibalism in response to nest failure of Black-crowned Night-Herons (Nycticorax nycticorax)

Science.gov (United States)

Brussee, Brianne E.; Coates, Peter S.; Dwight, Ian; Young, Laura G.

2017-01-01

During 2011, four separate instances of indirect filial cannibalism, whereby adults consumed their young that died from unknown causes, were observed using video-monitoring techniques in a nesting colony of Black-crowned Night-Herons (Nycticorax nycticorax) on Alcatraz Island. Though they were not observed actively killing their young, in all four observations adult Black-crowned Night-Herons consumed their young following death (i.e., indirect filial cannibalism). We could not determine cause of chick mortality, but parental neglect was likely a contributing factor in at least two instances. Indirect filial cannibalism is not commonly documented among birds, and understanding how cannibalism contributes to nest failure can help researchers better understand factors that limit nesting populations.

The effect on emotions and brain activity by the direct/indirect lighting in the residential environment.

Science.gov (United States)

Shin, Yu-Bin; Woo, Seung-Hyun; Kim, Dong-Hyeon; Kim, Jinseong; Kim, Jae-Jin; Park, Jin Young

2015-01-01

This study was performed to explore how direct/indirect lighting affects emotions and brain oscillations compared to the direct lighting when brightness and color temperature are controlled. Twenty-eight subjects (12 females; mean age 22.5) participated. The experimental conditions consisted of two lighting environments: direct/indirect lighting (400 lx downlight, 300 lx uplight) and direct lighting (700 lx downlight). On each trial, a luminance environment was presented for 4 min, followed by participants rated their emotional feelings of the lighting environment. EEG data were recorded during the experiment. Spectral analysis was performed for the range of delta, theta, alpha, beta, and gamma ranges. The participants felt cooler and more pleasant and theta oscillations on the F4, F8, T4, and TP7 electrodes were more enhanced in the direct/indirect lighting environment compared to the direct lighting environment. There was significant correlation between the "cool" rating and the theta power of the F8 electrode. The participants felt more pleasant in the direct/indirect lighting environment, indicating that space with direct/indirect lighting modulated subjective perception. Additionally, our results suggest that theta oscillatory activity can be used as a biological marker that reflects emotional status in different lighting environments. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Exploring Machine Learning Techniques Using Patient Interactions in Online Health Forums to Classify Drug Safety

Science.gov (United States)

Chee, Brant Wah Kwong

2011-01-01

This dissertation explores the use of personal health messages collected from online message forums to predict drug safety using natural language processing and machine learning techniques. Drug safety is defined as any drug with an active safety alert from the US Food and Drug Administration (FDA). It is believed that this is the first…

Analysis of indirect taxation in Ukraine

Directory of Open Access Journals (Sweden)

Khodyakova Olga V.

2014-01-01

Full Text Available The goal of the article is analysis of the structure and dynamics of indirect taxes for the previous five years and also the influence of indirect taxation upon formation of income of the State Budget of Ukraine. The article analyses the modern state of indirect taxation in Ukraine. Specific weight of the value added tax, excise tax and customs duty are considered in the structure of tax receipts of the consolidated budget of Ukraine as indirect taxes. The article shows that receipts of the State Budget of Ukraine are mostly provided by indirect taxes. The Ukrainian taxation system is mostly a factor of reduction of the level of economic growth and investment activity in the country and the existing system of administering is not completely capable of excluding the possibility of tax evasion. The prospect of further studies in this direction is improvement of organisation of tax control in Ukraine and differentiation of the value added tax rates depending on the level of consumption of goods and level of income of consumers.

17F breakup reactions: a touchstone for indirect measurements

International Nuclear Information System (INIS)

De Napoli, M.; Raciti, G.; Sfienti, C.; Capel, P.; Baye, D.; Descouvemont, P.; Sparenberg, J.-M.; Giacoppo, F.; Rapisarda, E.; Cardella, G.; Mazzocchi, C.

2011-01-01

An exclusive study of 17 F breakup reactions has been performed at the FRIBs facility of the Laboratori Nazionali del Sud in Catania (Italy). The experiment has been performed with the aim of testing the accuracy of the Coulomb-breakup indirect technique used to infer radiative-capture cross sections at low energies. This technique has been used in the 7 Be(p,γ) 8 B case, but has never been tested. By measuring the breakup of 17 F into 16 O+p, and comparing the inferred cross section for 16 O(p,γ) 17 F to direct precise measurements, the influence of E2 transitions and higher-order effects, that are predicted to be significant in Coulomb-breakup reactions, can be evaluated. The first results and preliminary model comparison are reported.

Indirect adaptive control of discrete chaotic systems

International Nuclear Information System (INIS)

Salarieh, Hassan; Shahrokhi, Mohammad

2007-01-01

In this paper an indirect adaptive control algorithm is proposed to stabilize the fixed points of discrete chaotic systems. It is assumed that the functionality of the chaotic dynamics is known but the system parameters are unknown. This assumption is usually applicable to many chaotic systems, such as the Henon map, logistic and many other nonlinear maps. Using the recursive-least squares technique, the system parameters are identified and based on the feedback linearization method an adaptive controller is designed for stabilizing the fixed points, or unstable periodic orbits of the chaotic maps. The stability of the proposed scheme has been shown and the effectiveness of the control algorithm has been demonstrated through computer simulations

Indirect Reciprocity under Incomplete Observation

Science.gov (United States)

Nakamura, Mitsuhiro; Masuda, Naoki

2011-01-01

Indirect reciprocity, in which individuals help others with a good reputation but not those with a bad reputation, is a mechanism for cooperation in social dilemma situations when individuals do not repeatedly interact with the same partners. In a relatively large society where indirect reciprocity is relevant, individuals may not know each other's reputation even indirectly. Previous studies investigated the situations where individuals playing the game have to determine the action possibly without knowing others' reputations. Nevertheless, the possibility that observers of the game, who generate the reputation of the interacting players, assign reputations without complete information about them has been neglected. Because an individual acts as an interacting player and as an observer on different occasions if indirect reciprocity is endogenously sustained in a society, the incompleteness of information may affect either role. We examine the game of indirect reciprocity when the reputations of players are not necessarily known to observers and to interacting players. We find that the trustful discriminator, which cooperates with good and unknown players and defects against bad players, realizes cooperative societies under seven social norms. Among the seven social norms, three of the four suspicious norms under which cooperation (defection) to unknown players leads to a good (bad) reputation enable cooperation down to a relatively small observation probability. In contrast, the three trustful norms under which both cooperation and defection to unknown players lead to a good reputation are relatively efficient. PMID:21829335

Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models.

Science.gov (United States)

Preacher, Kristopher J; Hayes, Andrew F

2008-08-01

Hypotheses involving mediation are common in the behavioral sciences. Mediation exists when a predictor affects a dependent variable indirectly through at least one intervening variable, or mediator. Methods to assess mediation involving multiple simultaneous mediators have received little attention in the methodological literature despite a clear need. We provide an overview of simple and multiple mediation and explore three approaches that can be used to investigate indirect processes, as well as methods for contrasting two or more mediators within a single model. We present an illustrative example, assessing and contrasting potential mediators of the relationship between the helpfulness of socialization agents and job satisfaction. We also provide SAS and SPSS macros, as well as Mplus and LISREL syntax, to facilitate the use of these methods in applications.

Natural isotope technique for the exploration and exploitation of ground water

International Nuclear Information System (INIS)

Zainal Abidin; Hudi Hastowo; Aang Hanafiah

2007-01-01

In line with the condition of climate and hydrology, Indonesia has a fast amount of aquifers which are sources of ground water. In several areas large number of springs occurred with small to large debits which is a sign of ground water potential. Ground water is a potential reservoir to be use at maximum for several purposes such as drinking water, industry and tourism. Large cities such as Jakarta, Bandung and others depend on ground water for their industries and hotels. The exploitation of ground water use has to be controlled and monitoring of a management system have to be done. Research carried out only on the exploitation of geophysics and hydrology showed that the amount of ground water reservoirs is not enough to be used when it comes to justification to explore it. Other parameters are still be needed which are the origins and dating of the ground water, these last two factors mentioned have to be taken into consideration in the system of conversion and balance of water. An alternative technology to determine the two factors mentioned in a short time is the natural isotope technique of 18 O, 2 H and 14 C. This technique is used to determine the origin of water, and isotope 14 C is carried out to determine the age of ground water. Isotopes 18 H and 2 H are stable isotopes in the form of water and is integrated in the hydrological cycle. Their specific concentrations in rain water at several elevations are used as fingerprints to locate the area of ground water supplement and its origin. Isotope 14 C is a natural radioactive isotope with a half-life of 5.730 years and is found in the hydrology cycle and enters the ground water system through CO 2 gas which is dissolved in water. 14 C isotope could determine the age of ground water and is also able to indicate the potential/amount of ground water. Studies of exploration and exploration monitoring of ground water should be an integrated study by geohydrology, geophysics and isotope and could be a solution of

An Indirect Route for Ethanol Production

Energy Technology Data Exchange (ETDEWEB)

Eggeman, T.; Verser, D.; Weber, E.

2005-04-29

The ZeaChem indirect method is a radically new approach to producing fuel ethanol from renewable resources. Sugar and syngas processing platforms are combined in a novel way that allows all fractions of biomass feedstocks (e.g. carbohydrates, lignins, etc.) to contribute their energy directly into the ethanol product via fermentation and hydrogen based chemical process technologies. The goals of this project were: (1) Collect engineering data necessary for scale-up of the indirect route for ethanol production, and (2) Produce process and economic models to guide the development effort. Both goals were successfully accomplished. The projected economics of the Base Case developed in this work are comparable to today's corn based ethanol technology. Sensitivity analysis shows that significant improvements in economics for the indirect route would result if a biomass feedstock rather that starch hydrolyzate were used as the carbohydrate source. The energy ratio, defined as the ratio of green energy produced divided by the amount of fossil energy consumed, is projected to be 3.11 to 12.32 for the indirect route depending upon the details of implementation. Conventional technology has an energy ratio of 1.34, thus the indirect route will have a significant environmental advantage over today's technology. Energy savings of 7.48 trillion Btu/yr will result when 100 MMgal/yr (neat) of ethanol capacity via the indirect route is placed on-line by the year 2010.

Performance comparison of direct and indirect lighting systems

International Nuclear Information System (INIS)

Rubinstein, F.; Morse, O.; Clark, T.

1993-01-01

The performance of a retrofitted indirect lighting system was compared to the performance of a typical de-lamped direct lighting system in a partitioned office space. Power, illuminance and luminance measurements were made for the de-lamped direct lighting system and after installation of the indirect lighting system with various lamp and ballast combinations. Using the same lamps and ballasts, average workplace illuminance was slightly higher with indirect lighting than with direct lighting. With indirect lighting, workplace lumen efficacy was 4.5% lower due to the higher power draw of the lamps in the more open and cooler indirect fixtures. Indirect lighting with 36 watt T-8 lamps and electronic ballasts achieved an initial average workplace illuminance of 45 foot-candles in the partitioned office space at only 1.1 w/ft 2

Comparison of two non-invasive methods of microbial analysis in surgery practice: incision swabbing and the indirect imprint technique.

Science.gov (United States)

Chovanec, Zdenek; Veverkova, Lenka; Votava, Miroslav; Svoboda, Jiri; Jedlicka, Vaclav; Capov, Ivan

2014-12-01

A variety of methods exist to take samples from surgical site infections for cultivation; however, an unambiguous and suitable method has not yet been defined. The aim of our retrospective non-randomized study was to compare two non-invasive techniques of sampling material for microbiologic analysis in surgical practice. We compared bacteria cultured from samples obtained with the use of the swab technique, defined in our study as the gold standard, with the indirect imprint technique. A cotton-tipped swab (Copan, Brescia, Italy) was used; the imprints were taken using Whatman no. 4 filter paper (Macherey-Nagal, Duren, Germany) cut into 5×5 cm pieces placed on blood agar in a Petri dish. To culture the microorganisms in the microbiology laboratory, we used blood agar, UriSelect 4 medium (Bio-Rad, Marnes-la-Coquette, France), and a medium with sodium chloride (blood agar with salt). After careful debridement, a sample was taken from the incision surface by swab and subsequently the same area of the surface was imprinted onto filter paper. The samples were analyzed in the microbiology laboratory under standard safety precautions. The cultivation results of the two techniques were processed statistically using contingency tables and the McNemar test. Those samples that were simultaneously cultivation-positive by imprint and -negative by swabbing were processed in greater detail. Over the period between October 2008 and March 2013, 177 samples from 70 patients were analyzed. Sampling was carried out from 42 males and 28 females. One hundred forty-six samples were from incisions after operations (21 samples from six patients after operation on the thoracic cavity, 73 samples from 35 patients after operation on the abdominal cavity combined with the gastrointestinal tract, 52 samples from 19 patients with other surgical site infections not included above) and 31 samples from 11 patients with no post-operative infection. One patient had a sample taken both from a post

48 CFR 1631.203-70 - Allocation techniques.

Science.gov (United States)

2010-10-01

... shall consistently apply the methods and techniques established to classify direct and indirect costs... meant to be exhaustive, but rather are examples of allocation methods that may be acceptable under... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Allocation techniques. 1631...

Exploration of inclusion complexes of neurotransmitters with β-cyclodextrin by physicochemical techniques

Science.gov (United States)

Roy, Mahendra Nath; Saha, Subhadeep; Kundu, Mitali; Saha, Binoy Chandra; Barman, Siti

2016-07-01

Molecular assemblies of β-cyclodextrin with few of the most important neurotransmitters, viz., dopamine hydrochloride, tyramine hydrochloride and (±)-epinephrine hydrochloride in aqueous medium have been explored by reliable spectroscopic and physicochemical techniques as potential drug delivery systems. Job plots confirm the 1:1 host-guest inclusion complexes, while surface tension and conductivity studies illustrate the inclusion process. The inclusion complexes were characterized by 1H NMR spectroscopy and association constants have been calculated by using Benesi-Hildebrand method. Thermodynamic parameters for the formation of inclusion complexes have been derived by van't Hoff equation, which demonstrate that the overall inclusion processes are thermodynamically favorable.

Ballistic fractures: indirect fracture to bone.

Science.gov (United States)

Dougherty, Paul J; Sherman, Don; Dau, Nathan; Bir, Cynthia

2011-11-01

Two mechanisms of injury, the temporary cavity and the sonic wave, have been proposed to produce indirect fractures as a projectile passes nearby in tissue. The purpose of this study is to evaluate the temporal relationship of pressure waves using strain gauge technology and high-speed video to elucidate whether the sonic wave, the temporary cavity, or both are responsible for the formation of indirect fractures. Twenty-eight fresh frozen cadaveric diaphyseal tibia (2) and femurs (26) were implanted into ordnance gelatin blocks. Shots were fired using 9- and 5.56-mm bullets traversing through the gelatin only, passing close to the edge of the bone, but not touching, to produce an indirect fracture. High-speed video of the impact event was collected at 20,000 frames/s. Acquisition of the strain data were synchronized with the video at 20,000 Hz. The exact time of fracture was determined by analyzing and comparing the strain gauge output and video. Twenty-eight shots were fired, 2 with 9-mm bullets and 26 with 5.56-mm bullets. Eight indirect fractures that occurred were of a simple (oblique or wedge) pattern. Comparison of the average distance of the projectile from the bone was 9.68 mm (range, 3-20 mm) for fractured specimens and 15.15 mm (range, 7-28 mm) for nonfractured specimens (Student's t test, p = 0.036). In this study, indirect fractures were produced after passage of the projectile. Thus, the temporary cavity, not the sonic wave, was responsible for the indirect fractures.

Indirect effects in dual radiation action

International Nuclear Information System (INIS)

Zaider, M.; Rossi, H.H.

1988-01-01

The basic aim in this paper is to establish the link between indirect effects of radiation action and the spatial distribution of radicals at the time of energy deposition as well as throughout subsequent diffusion and interaction. The fact that radicals diffuse for a finite distance before damaging a biomolecule has dramatic effects on their subsequent probability to result in lesions. Thus at very low DMSO concentrations, where p = 0.5, one expects - all other things being equal - some 75% of the lesions to result from indirect or semidirect lesions. The number calculated here is lower (15%), a direct result of the fact that such lesions involve proximity functions modulated by diffusion. At higher DMSO concentrations this percentage becomes progressively smaller, as expected. It appears thus that for low-LET radiation, the relative amount of indirect damage in single tracks (also termed intratrack or single events) action is very small. By contrast, intertrack (or two-event) contributions will have the ratio between direct and (indirect + semidirect) contributions given by p 2 /(1-p 2 ). The reason for this is that sublesions from different tracks are uniformly distributed throughout the cell nucleus; their probability of interaction should not depend on any previous diffusional processes. For the example given above (p = 0.5) they do expect 65% of intertrack (two-hit) lesions to have resulted from indirect or semidirect mechanisms. This contrast between the almost exclusively direct character of intratrack lesions and the dominant role of indirect action in intertrack lesions produced by low-LET radiation is an important conclusion of this study

Expression of future prospective in indirect speech

Directory of Open Access Journals (Sweden)

Bodnaruk Elena Vladimirovna

2015-03-01

Full Text Available The article analyzes the characteristics and use of grammatical semantics and lexical and grammatical means used to create future prospects in double indirect discourse. The material for the study were epic works by contemporary German writers. In the analysis of the empirical material it has been pointed out that indirect discourse has preterial basis and is the kind of most frequent inner speech of characters. The most widely used form with future semantics in preterial indirect speech is conditional I, formally having a conjunctive basis, but is mostly used with the indicative semantics. Competitive to conditional I in indirect speech is preterial indicative. A characteristic feature of the indirect speech is the use of modal verbs, which, thanks to its semantics is usually referred as an action at a later term, creating the prospect of future statements. The most frequent were modal verbs wollen and sollen in the form of the preterite, more rare verbs were m ssen and k nnen. German indirect speech distinguishes the ability to use forms on the basis of conjunctive: preterite and plusquamperfect of conjunctive. Both forms express values similar to those of the indicative. However, conjunctive forms the basis of the data shown in a slightly more pronounced seme of uncertainty that accompanies future uses of these forms in indirect speech. In addition, plusquamperfect conjunctive differs from others by the presence of the seme of completeness.

Synchronization of indirectly coupled Lorenz oscillators

Indian Academy of Sciences (India)

Synchronization of indirectly coupled Lorenz oscillators: An experimental study. Amit Sharma Manish Dev Shrimali. Synchronization, Coupled Systems and Networks Volume 77 Issue 5 November 2011 pp 881-889 ... The in-phase and anti-phase synchronization of indirectly coupled chaotic oscillators reported in Phys. Rev ...

Indirect estimators in US federal programs

CERN Document Server

1996-01-01

In 1991, a subcommittee of the Federal Committee on Statistical Methodology met to document the use of indirect estimators - that is, estimators which use data drawn from a domain or time different from the domain or time for which an estimate is required. This volume comprises the eight reports which describe the use of indirect estimators and they are based on case studies from a variety of federal programs. As a result, many researchers will find this book provides a valuable survey of how indirect estimators are used in practice and which addresses some of the pitfalls of these methods.

Indirectional statistics and the significance of an asymmetry discovered by Birch

International Nuclear Information System (INIS)

Kendall, D.G.; Young, G.A.

1984-01-01

Birch (1982, Nature, 298, 451) reported an apparent 'statistical asymmetry of the Universe'. The authors here develop 'indirectional analysis' as a technique for investigating statistical effects of this kind and conclude that the reported effect (whatever may be its origin) is strongly supported by the observations. The estimated pole of the asymmetry is at RA 13h 30m, Dec. -37deg. The angular error in its estimation is unlikely to exceed 20-30deg. (author)

Innovations in uranium exploration, mining and processing techniques, and new exploration target areas. Proceedings of a technical committee meeting held in Vienna, 5-8 December 1994

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-03-01

In 1994 there were 432 nuclear power plants in operation with a combined electricity generating capacity of 340 347 MWe. To achieve this, 58,000 tonnes of uranium were required as nuclear fuel. In view of its economic importance, the International Atomic Energy Agency has had a long-standing interest in uranium exploration, resources, production and demand. This is reflected in numerous publications covering different aspects of this field. Particularly worth mentioning is the periodical ``Uranium Resources, Production and Demand``, published jointly with the Nuclear Energy Agency of the OECD. Its fourteenth edition was published in early 1994. It was the objective of this Technical Committee meeting, the proceedings of which are presented in this TECDOC, to bring together specialists in the field and to collect information on new developments in exploration, mining techniques and innovative methods of processing that are more environmentally friendly. The meeting was attended by a total of 22 participants from 14 countries. Eleven papers were presented describing new exploration areas, improvements in processing methods, new mining techniques for the extraction of high grade ore, and innovative approaches for site reclamation. Two working groups were organized and dealt with the analysis of world uranium resources and the new direction of research in mining and ore processing. Refs, figs, tabs.

The Trojan Horse method as an indirect approach for nuclear astrophysics studies

Energy Technology Data Exchange (ETDEWEB)

Tumino, A; Spitaleri, C; Cherubini, S; Cognata, M La; Lamia, L; Pizzone, R G; Puglia, S M R; Rapisarda, G G; Romano, S; Sergi, M L, E-mail: tumino@lns.infn.i [Laboratori Nazionali del Sud - INFN, Catania (Italy)

2010-01-01

The Trojan Horse method (THM) is a powerful indirect technique that provides a successful alternative path to determine the bare nucleus astrophysical S(E) factor for rearrangement reactions down to astrophysical energies. This is done by measuring the cross section for a suitable three body process in the quasi-free kinematics regime. Prescriptions and basic features will be presented together with some applications to demonstrate how THM works.

THE INDIRECT OBJECT (IO) – ALBANIAN AND ENGLISH

OpenAIRE

Shkelqim Millaku; Xhevahire Topanica

2016-01-01

The aim of this study is too corporate the function of the indirect object between Albanian and English language. The function and the Albanian typical case for indirect object are dative and ablative. This grammatical phenomena is the full contrast between two languages because in English language doesn’t exist dative and ablative us in Albanian. In Albanian and English language, the indirect object is more heterogenic than the direct object. The indirect (direct) object in both of languages...

Approbation of Personality Questionnaire by N.B. Astanina “A Technique for Exploring Self-Trust”

Directory of Open Access Journals (Sweden)

Runets O.V.

2015-12-01

Full Text Available This paper reviews the concept of one of the basic personality traits, ‘self-trust’, and describes a tool for measuring it — a questionnaire “A Technique for Exploring Self-Trust” developed by N.B. Astanina. The questionnaire was tested on a sample of adults. Analysis of validity and reliability showed satisfactory outcomes proving that the questionnaire can be applied in research.

Exploration Challenges: Transferring Ground Repair Techniques to Space Flight Application

Science.gov (United States)

McLemore, Carole A.; Kennedy, James P.; Rose, Frederick A.; Evans, Brian W.

2007-01-01

Fulfilling NASA's Vision for Space Exploration will demand an extended presence in space at distances from our home planet that exceed our current experience in space logistics and maintenance. The ability to perform repairs in lieu of the customary Orbital Replacement Unit (ORU) process where a faulty part is replaced will be elevated from contingency to routine to sustain operations. The use and cost effectiveness of field repairs for ground based operations in industry and the military have advanced with the development of technology in new materials, new repair techniques and new equipment. The unique environments, accessibility constraints and Extra Vehicular Activity (EVA) issues of space operations will require extensive assessment and evolution of these technologies to provide an equivalent and expected level of assurance to mission success. Challenges include the necessity of changes in design philosophy and policy, extremes in thermal cycling, disruptive forces (such as static charge and wind entrainment) on developed methods for control of materials, dramatically increased volatility of chemicals for cleaning and other compounds due to extremely low pressures, the limits imposed on dexterity and maneuverability by current EVA equipment and practices, and the necessity of unique verification methodology. This paper describes these challenges in and discusses the effects on the established ground techniques for repair. The paper also describes the leading repair methodology candidates and their beneficial attributes for resolving these issues with the evolution of technology.

Uranium exploration data and techniques applied to the preparation of radioelement maps. Proceedings of a technical committee meeting

International Nuclear Information System (INIS)

1997-11-01

The report reviews the advantage and pitfalls of using uranium exploration data and techniques as well as other methods for the preparation of radioelement and radon maps for baseline information in environmental studies and monitoring

Comparison of viral RNA electrophoresis and indirect ELISA methods in the diagnosis of human rotavirus infection

Energy Technology Data Exchange (ETDEWEB)

Avendano, L F; Dubinovsky, S; James, Jr, H D

1984-01-01

A total of 177 stool samples from Chilean diarrhea patients under two years of age were tested for rotavirus by two methods - the indirect enzyme-linked immunosorbent assay (indirect ELISA) and viral RNA electrophoresis in agarose gels (v RNA EPH). Fifty of the specimens came from patients with acute diarrhea and 127 came from patients with protracted diarrhea. The indirect ELISA testing was performed at the National Institutes of Health in the United States: the electrophoretic testing was carried out in Santiago, Chile by the authors. The electrophoretic method detected rotavirus in 36% of the acute samples and 25% of the samples from protracted cases, while the indirect ELISA method detected rotavirus in higher percentages of samples - 46% and 38%, respectively. These results support the conclusion that v RNA EPH is a less sensitive method for detecting rotavirus than the indirect ELISA. Nevertheless, the former method's high specificity, ease of application, and low cost make it a worthwhile alternative to indirect ELISA. Thus, considering the important role played by rotavirus in infant diarrhea and the need for a diagnostic technique that can be incorporated into the routines of medical center laboratories in developing countries, there is good reason to conclude that v RNA EPH is a useful tool for studying rotavirus diarrhea. 18 refs, 3 tabs. Also published in the Bol. Oficina Sanit. Panam. (1984) v. 97(1), p. 1-7 (In Spanish).

An Approach to Dynamic Line Rating State Estimation at Steady State Using Direct and Indirect Measurements

DEFF Research Database (Denmark)

Alvarez, David; Silva, Filipe Miguel Faria da; Mombello, Enrique E.

2018-01-01

Dynamic line rating has emerged as a solution for reducing congestion in overhead lines, allowing the optimization of power systems assets. This technique is based on direct and/or indirect monitoring of conductor temperature. Different devices and methods have been developed to sense conductor...

Indirect Medical Education and Disproportionate Share Adj...

Data.gov (United States)

U.S. Department of Health & Human Services — Indirect Medical Education and Disproportionate Share Adjustments to Medicare Inpatient Payment Rates The indirect medical education (IME) and disproportionate share...

Fuel optimization for low-thrust Earth-Moon transfer via indirect optimal control

Science.gov (United States)

Pérez-Palau, Daniel; Epenoy, Richard

2018-02-01

The problem of designing low-energy transfers between the Earth and the Moon has attracted recently a major interest from the scientific community. In this paper, an indirect optimal control approach is used to determine minimum-fuel low-thrust transfers between a low Earth orbit and a Lunar orbit in the Sun-Earth-Moon Bicircular Restricted Four-Body Problem. First, the optimal control problem is formulated and its necessary optimality conditions are derived from Pontryagin's Maximum Principle. Then, two different solution methods are proposed to overcome the numerical difficulties arising from the huge sensitivity of the problem's state and costate equations. The first one consists in the use of continuation techniques. The second one is based on a massive exploration of the set of unknown variables appearing in the optimality conditions. The dimension of the search space is reduced by considering adapted variables leading to a reduction of the computational time. The trajectories found are classified in several families according to their shape, transfer duration and fuel expenditure. Finally, an analysis based on the dynamical structure provided by the invariant manifolds of the two underlying Circular Restricted Three-Body Problems, Earth-Moon and Sun-Earth is presented leading to a physical interpretation of the different families of trajectories.

Exploring compression techniques for ROOT IO

Science.gov (United States)

Zhang, Z.; Bockelman, B.

2017-10-01

ROOT provides an flexible format used throughout the HEP community. The number of use cases - from an archival data format to end-stage analysis - has required a number of tradeoffs to be exposed to the user. For example, a high “compression level” in the traditional DEFLATE algorithm will result in a smaller file (saving disk space) at the cost of slower decompression (costing CPU time when read). At the scale of the LHC experiment, poor design choices can result in terabytes of wasted space or wasted CPU time. We explore and attempt to quantify some of these tradeoffs. Specifically, we explore: the use of alternate compressing algorithms to optimize for read performance; an alternate method of compressing individual events to allow efficient random access; and a new approach to whole-file compression. Quantitative results are given, as well as guidance on how to make compression decisions for different use cases.

Indirect Comorbidity in Childhood and Adolescence

Directory of Open Access Journals (Sweden)

William eCopeland

2013-11-01

Full Text Available Objective: Comorbidity between psychiatric disorders is common, but pairwise associations between two disorders may be explained by the presence of other diagnoses that are associated with both disorders or indirect comorbidity. Method: Comorbidities of common childhood psychiatric disorders were tested in three community samples of children ages 6 to 17 (8931 observations of 2965 subjects. Psychiatric disorder status in all three samples was assessed with the Child and Adolescent Psychiatric Assessment. Indirect comorbidity was defined as A-B associations that decreased from significance to nonsignificance after adjusting for other disorders. Results: All tested childhood psychiatric disorders were positively associated in bivariate analyses. After adjusting for comorbidities, many ssociations involving a behavioral disorder and an emotional disorder were attenuated suggesting indirect comorbidity. Generalized anxiety and depressive disorders displayed a very high level of overlap (adjusted OR=37.9. All analyses were rerun with depressive disorders grouped with generalized anxiety disorder in a single distress disorders category. In these revised models, all associations between and emotional disorder and a behavior disorder met our criteria for indirect comorbidity except for the association of oppositional defiant disorder with distress disorders (OR=11.3. Follow-up analyses suggested that the indirect associations were primarily accounted for by oppositional defiant disorder and the distress disorder category. There was little evidence of either sex differences or differences by developmental period Conclusions: After accounting for the overlap between depressive disorders with generalized anxiety disorder, direct comorbidity between emotional and behavioral disorders was uncommon. When there was evidence of indirect comorbidity, ODD and distress disorders were the key intermediary diagnoses accounting for the apparent associations.

An Exploration of Relationships between Leadership and Student Citizenship Outcomes in Cyprus Middle Schools

Science.gov (United States)

Savvides, Vassos; Pashiardis, Petros

2016-01-01

Purpose: The main purpose of this study was to explore direct and indirect relationships between Leadership and Student Citizenship Outcomes in Cyprus middle schools. In the case of indirect effects the mediating role of School Academic Optimism and Instructional Quality was examined. Method: The specific study adopted a value-added quantitative…

Indirect Fabrication of Lattice Metals with Thin Sections Using Centrifugal Casting.

Science.gov (United States)

Mun, Jiwon; Ju, Jaehyung; Thurman, James

2016-05-14

One of the typical methods to manufacture 3D lattice metals is the direct-metal additive manufacturing (AM) process such as Selective Laser Melting (SLM) and Electron Beam Melting (EBM). In spite of its potential processing capability, the direct AM method has several disadvantages such as high cost, poor surface finish of final products, limitation in material selection, high thermal stress, and anisotropic properties of parts. We propose a cost-effective method to manufacture 3D lattice metals. The objective of this study is to provide a detailed protocol on fabrication of 3D lattice metals having a complex shape and a thin wall thickness; e.g., octet truss made of Al and Cu alloys having a unit cell length of 5 mm and a cell wall thickness of 0.5 mm. An overall experimental procedure is divided into eight sections: (a) 3D printing of sacrificial patterns (b) melt-out of support materials (c) removal of residue of support materials (d) pattern assembly (e) investment (f) burn-out of sacrificial patterns (g) centrifugal casting (h) post-processing for final products. The suggested indirect AM technique provides the potential to manufacture ultra-lightweight lattice metals; e.g., lattice structures with Al alloys. It appears that the process parameters should be properly controlled depending on materials and lattice geometry, observing the final products of octet truss metals by the indirect AM technique.

Uranium exploration data and techniques applied to the preparation of radioelement maps. Proceedings of a technical committee meeting

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-11-01

The report reviews the advantage and pitfalls of using uranium exploration data and techniques as well as other methods for the preparation of radioelement and radon maps for baseline information in environmental studies and monitoring. Refs, figs, tabs.

Identification of Indirect Effects in a Cognitive Patient Education (COPE) Intervention for Low Back Pain.

Science.gov (United States)

Mansell, Gemma; Storheim, Kjersti; Løchting, Ida; Werner, Erik L; Grotle, Margreth

2017-12-01

Many interventions for the treatment of low back pain exist, but the mechanisms through which such treatments work are not always clear. This situation is especially true for biopsychosocial interventions that incorporate several different components and methods of delivery. The study objective was to examine the indirect effects of the Cognitive Patient Education (COPE) intervention via illness perceptions, back pain myths, and pain catastrophizing on disability outcome. This study was a secondary analysis of the COPE randomized controlled trial. Mediation analysis techniques were employed to examine the indirect effects of the COPE intervention via residualized change (baseline - posttreatment) in the 3 variables hypothesized to be targeted by the COPE intervention on posttreatment disability outcome. Pain intensity at baseline, pain duration, clinician type, and a treatment-mediator interaction term were controlled for in the analysis. Preliminary analyses confirmed that changes in pain catastrophizing and illness perceptions (not back pain myths) were related to both allocation to the intervention arm and posttreatment disability score. The treatment exerted statistically significant indirect effects via changes in illness perceptions and pain catastrophizing on posttreatment disability score (illness perceptions standardized indirect effect = 0.09 [95% CI = 0.03 to 0.16]; pain catastrophizing standardized indirect effect = 0.05 [95% CI = 0.01 to 0.12]). However, the inclusion of an interaction term led to the indirect effects being significantly reduced, with the effects no longer being statistically significant. This study presents a secondary analysis of variables not identified a priori as being potentially important treatment targets; other, unmeasured factors could also be important in explaining treatment effects. The finding that small indirect effects of the COPE intervention via changes in illness perceptions and pain catastrophizing on posttreatment

Indirect immobilized Jagged1 suppresses cell cycle progression and induces odonto/osteogenic differentiation in human dental pulp cells.

Science.gov (United States)

Manokawinchoke, Jeeranan; Nattasit, Praphawi; Thongngam, Tanutchaporn; Pavasant, Prasit; Tompkins, Kevin A; Egusa, Hiroshi; Osathanon, Thanaphum

2017-08-31

Notch signaling regulates diverse biological processes in dental pulp tissue. The present study investigated the response of human dental pulp cells (hDPs) to the indirect immobilized Notch ligand Jagged1 in vitro. The indirect immobilized Jagged1 effectively activated Notch signaling in hDPs as confirmed by the upregulation of HES1 and HEY1 expression. Differential gene expression profiling using an RNA sequencing technique revealed that the indirect immobilized Jagged1 upregulated genes were mainly involved in extracellular matrix organization, disease, and signal transduction. Downregulated genes predominantly participated in the cell cycle, DNA replication, and DNA repair. Indirect immobilized Jagged1 significantly reduced cell proliferation, colony forming unit ability, and the number of cells in S phase. Jagged1 treated hDPs exhibited significantly higher ALP enzymatic activity, osteogenic marker gene expression, and mineralization compared with control. Pretreatment with a γ-secretase inhibitor attenuated the Jagged1-induced ALP activity and mineral deposition. NOTCH2 shRNA reduced the Jagged1-induced osteogenic marker gene expression, ALP enzymatic activity, and mineral deposition. In conclusion, indirect immobilized Jagged1 suppresses cell cycle progression and induces the odonto/osteogenic differentiation of hDPs via the canonical Notch signaling pathway.

Direct and indirect links between organizational work-home culture and employee well-being

OpenAIRE

Beauregard, T. Alexandra

2011-01-01

The extent to which an organization's culture exhibits support for its employees' efforts to balance work and personal responsibilities has been shown to influence a number of work- and home-related outcomes. This study tests a model with a mix of mediated and moderated relationships to investigate direct and indirect routes by which work-home culture may affect employee well-being. Sex differences in these relationships are also explored. Data collected from public sector employees in the UK...

Direct and indirect punishment among strangers in the field.

Science.gov (United States)

Balafoutas, Loukas; Nikiforakis, Nikos; Rockenbach, Bettina

2014-11-11

Many interactions in modern human societies are among strangers. Explaining cooperation in such interactions is challenging. The two most prominent explanations critically depend on individuals' willingness to punish defectors: In models of direct punishment, individuals punish antisocial behavior at a personal cost, whereas in models of indirect reciprocity, they punish indirectly by withholding rewards. We investigate these competing explanations in a field experiment with real-life interactions among strangers. We find clear evidence of both direct and indirect punishment. Direct punishment is not rewarded by strangers and, in line with models of indirect reciprocity, is crowded out by indirect punishment opportunities. The existence of direct and indirect punishment in daily life indicates the importance of both means for understanding the evolution of cooperation.

JUSTIFICATION FOR INDIRECT DISCRIMINATION IN EU

Directory of Open Access Journals (Sweden)

Cătălina-Adriana Ivănuş

2014-11-01

Full Text Available The right to non-discrimination is very important for a civilized society. EU legislation establishes direct and indirect discrimination, harassment, sexual harassment, instruction to discriminate and any less favourable treatment of a woman related to pregnancy or maternity leave as forms of discrimination. The law and the Court of Justice permit the justification of indirect discrimination.

JUSTIFICATION FOR INDIRECT DISCRIMINATION IN EU

OpenAIRE

Cătălina-Adriana Ivănuş

2014-01-01

The right to non-discrimination is very important for a civilized society. EU legislation establishes direct and indirect discrimination, harassment, sexual harassment, instruction to discriminate and any less favourable treatment of a woman related to pregnancy or maternity leave as forms of discrimination. The law and the Court of Justice permit the justification of indirect discrimination.

Trends in exploration and exploration equipment for uranium

International Nuclear Information System (INIS)

Raitz, C.H.

1976-01-01

Uranium exploration once again is in a ''boom'' cycle. The energy needs of the OPEC and non-OPEC countries alike have created a demand for uranium which appears certain to increase in future years. In turn, this demand has stimulated a dramatic rise in both the price of uranium and the exploration activity necessary to discover new reserves. One immediate reaction to the sudden increase in uranium exploration activity has been the evaluation of old exploration methods and equipment. This paper briefly reviews some of the traditional equipment and techniques which currently are being refined and updated. Undoubtedly this equipment, complemented with good exploration planning and judgment, will continue to be relied upon for many years and will lead to the discovery of many new deposits. The paper also covers in greater detail some of the newer, less conventional techniques and equipment now being introduced for uranium exploration. These new methods may be expected to keep this country in the forefront among the uranium producers of the world

Enhanced Indirect Somatic Embryogenesis of Date Palm Using Low Levels of Seawater.

Science.gov (United States)

Taha, Rania A

2017-01-01

Date palm tolerates salinity, drought, and high temperatures. Arid and semiarid zones, especially the Middle East region, need a huge number of date palms for cultivation. To meet this demand, tissue culture techniques have great potential for mass production of plantlets, especially using the indirect embryogenesis technique; any improvement of these techniques is a worthy objective. Low levels of salinity can enhance growth and development of tolerant plants. A low level of seawater, a natural source of salinity, reduces the time required for micropropagation processes of date palm cv. Malkaby when added to MS medium. Medium containing seawater at 500 ppm total dissolved solid (TDS) (12.2 mL/L) improves callus proliferation, whereas 1500 ppm (36.59 mL/L) enhances plant regeneration including multiplication of secondary embryos, embryo germination, and rooting.

Direct and Indirect Influence of Non-Native Neighbours on Pollination and Fruit Production of a Native Plant.

Directory of Open Access Journals (Sweden)

Ana Montero-Castaño

Full Text Available Entomophilous non-native plants can directly affect the pollination and reproductive success of native plant species and also indirectly, by altering the composition and abundance of floral resources in the invaded community. Separating direct from indirect effects is critical for understanding the mechanisms underlying the impacts of non-native species on recipient communities.Our aims are: (a to explore both the direct effect of the non-native Hedysarum coronarium and its indirect effect, mediated by the alteration of floral diversity, on the pollinator visitation rate and fructification of the native Leopoldia comosa and (b to distinguish whether the effects of the non-native species were due to its floral display or to its vegetative interactions.We conducted field observations within a flower removal experimental setup (i.e. non-native species present, absent and with its inflorescences removed at the neighbourhood scale.Our study illustrates the complexity of mechanisms involved in the impacts of non-native species on native species. Overall, Hedysarum increased pollinator visitation rates to Leopoldia target plants as a result of direct and indirect effects acting in the same direction. Due to its floral display, Hedysarum exerted a direct magnet effect attracting visits to native target plants, especially those made by the honeybee. Indirectly, Hedysarum also increased the visitation rate of native target plants. Due to the competition for resources mediated by its vegetative parts, it decreased floral diversity in the neighbourhoods, which was negatively related to the visitation rate to native target plants. Hedysarum overall also increased the fructification of Leopoldia target plants, even though such an increase was the result of other indirect effects compensating for the observed negative indirect effect mediated by the decrease of floral diversity.

Indirect Genetic Effects for group-housed animals

DEFF Research Database (Denmark)

Alemu, Setegn Worku

This thesis investigated social interactions in group-housed animals. The main findings of this thesis: 1) Statistical methods to estimate indirect genetic effects when interactions differ between kin vs. non-kin were developed. 2) Indirect genetic effects contribute a substantial amount...... of heritable variation for bite mark traits in group-housed min. 3) Indirect genetic effects estimation needs to take into account systematic interactions due to sex or kin for bite mark trait in group-housed min. 4) Genomic selection can be used to increase the response to selection for survival time in Brown...

Indirect questioning method reveals hidden support for female genital cutting in South Central Ethiopia.

Science.gov (United States)

Gibson, Mhairi A; Gurmu, Eshetu; Cobo, Beatriz; Rueda, María M; Scott, Isabel M

2018-01-01

Female genital cutting (FGC) has major implications for women's physical, sexual and psychological health, and eliminating the practice is a key target for public health policy-makers. To date one of the main barriers to achieving this has been an inability to infer privately-held views on FGC within communities where it is prevalent. As a sensitive (and often illegal) topic, people are anticipated to hide their true support for the practice when questioned directly. Here we use an indirect questioning method (unmatched count technique) to identify hidden support for FGC in a rural South Central Ethiopian community where the practice is common, but thought to be in decline. Employing a socio-demographic household survey of 1620 Arsi Oromo adults, which incorporated both direct and indirect direct response (unmatched count) techniques we compare directly-stated versus privately-held views in support of FGC, and individual variation in responses by age, gender and education and target female (daughters versus daughters-in-law). Both genders express low support for FGC when questioned directly, while indirect methods reveal substantially higher acceptance (of cutting both daughters and daughters-in-law). Educated adults (those who have attended school) are privately more supportive of the practice than they are prepared to admit openly to an interviewer, indicating that education may heighten secrecy rather than decrease support for FGC. Older individuals hold the strongest views in favour of FGC (particularly educated older males), but they are also more inclined to conceal their support for FGC when questioned directly. As these elders represent the most influential members of society, their hidden support for FGC may constitute a pivotal barrier to eliminating the practice in this community. Our results demonstrate the great potential for indirect questioning methods to advance knowledge and inform policy on culturally-sensitive topics like FGC; providing more

Indirectness in Discourse: Ethnicity as Conversational Style.

Science.gov (United States)

Tannen, Deborah

1981-01-01

Examines social differences in expectations of indirectness in conversations between married couples, both Greek and Greek-American. Concludes that Greeks are more likely to expect indirectness in the context presented and that Greek-Americans have retained the Greek communicative patterns. (FL)

Manifestation of Aerosol Indirect Effects in Arctic Clouds

Science.gov (United States)

Lubin, D.; Vogelmann, A. M.

2009-12-01

The first aerosol indirect effect has traditionally been conceived as an enhancement of shortwave cloud reflectance in response to decreased effective droplet size at fixed liquid water path, as cloud nucleating aerosol becomes entrained in the cloud. The high Arctic, with its pervasive low-level stratiform cloud cover and frequent episodes of anthropogenic aerosol (Artic "haze"), has in recent years served as a natural laboratory for research on actual manifestations of aerosol indirect effects. This paper will review the surprising set of developments: (1) the detection of the indirect effect as a source of surface warming, rather than cooling, throughout early spring, (2) a transition to a cooling effect in late spring, corresponding to the beginning of the sea ice melt season, and (3) detection of an indirect effect during summer, outside of the "Arctic haze" season. This paper will also discuss measurements of spectral shortwave irradiance (350-2200 nm) made at Barrow, Alaska, during the U.S. Department of Energy's Indirect and Semi-Direct Aerosol Campaign (ISDAC), which reveal complications in our conception of the indirect effect related to the ice phase in Arctic stratiform clouds.

Smoking Cessation Is Associated With Lower Indirect Costs.

Science.gov (United States)

Baker, Christine L; Bruno, Marianna; Emir, Birol; Li, Vicky W; Goren, Amir

2018-06-01

This study quantified differences in indirect costs due to decreased work productivity between current and former smokers. Former smokers were further categorized by number of years since quitting to assess corresponding differences. Data on employed individuals were obtained from the 2013 US National Health and Wellness Survey (NHWS; N = 75,000). Indirect costs were calculated for current smokers and former smokers from weekly wages based on age and sex. The annual total indirect costs for current smokers were $1327.53, $1560.18, and $1839.87 higher than for those who quit 0 to 4 years, 5 to 10 years, and more than or equal to 11 years prior, respectively. There were no significant differences in mean total indirect costs between the former smoker groups. Current smokers showed significantly higher total annual indirect costs compared with former smokers, independently of the number of years since quitting smoking.

On the Relative Size of Direct and Indirect Taxation

OpenAIRE

Soldatos, Gerasimos T.

2014-01-01

Modifying the standard analytical apparatuses for direct and indirect tax evasion to incorporate forward indirect tax shift in a monopolistically competitive environment, this paper maintains that indirect tax evasion would exceed for sure direct tax evasion only under consumer risk neutrality and a tax policy zeroing the tax shift. Also, in the presence of tax evasion, there cannot be optimal direct-indirect tax mix, because tax evasion is accompanied by uncertainty and hence, nonlinearities...

Direct and indirect assessment of skeletal muscle blood flow in chronic congestive heart failure

International Nuclear Information System (INIS)

LeJemtel, T.H.; Scortichini, D.; Katz, S.

1988-01-01

In patients with chronic congestive heart failure (CHF), skeletal muscle blood flow can be measured directly by the continuous thermodilution technique and by the xenon-133 clearance method. The continuous thermodilution technique requires retrograde catheterization of the femoral vein and, thus, cannot be repeated conveniently in patients during evaluation of pharmacologic interventions. The xenon-133 clearance, which requires only an intramuscular injection, allows repeated determination of skeletal muscle blood flow. In patients with severe CHF, a fixed capacity of the skeletal muscle vasculature to dilate appears to limit maximal exercise performance. Moreover, the changes in peak skeletal muscle blood flow noted during long-term administration of captopril, an angiotensin-converting enzyme inhibitor, appears to correlate with the changes in aerobic capacity. In patients with CHF, resting supine deep femoral vein oxygen content can be used as an indirect measurement of resting skeletal muscle blood flow. The absence of a steady state complicates the determination of peak skeletal muscle blood flow reached during graded bicycle or treadmill exercise in patients with chronic CHF. Indirect assessments of skeletal muscle blood flow and metabolism during exercise performed at submaximal work loads are currently developed in patients with chronic CHF

Geophysical techniques for exploration of concealed uranium deposits in the Gwalior basin

International Nuclear Information System (INIS)

Choudhary, Kalpan; Singh, R.B.

2004-01-01

There is no direct geophysical method for the exploration of concealed uranium ore. Scope of geophysics for this in the Gwalior basin comprises delineating the basement topography, demarcation or zones of intense fracturing intersecting the unconformities and to identify the presence of carbonaceous rocks, specially in the graben-like structures. These geophysical problems have been successfully solved in other places by employing IP, resistivity, SP and gravity techniques for basement mapping, identification of fracture zone/shear zone, delineation of electrical conductors like carbonaceous rocks and sulphides. Three such case histories are presented here that include: a). basement and shear/fracture zone mapping in the Vindhyan basin north of Son-Narmada lineament, b). delineation of conductive zone (proved to be carbon phyllite) in the Mahakoshal Group of Kanhara area of Sonbhadra district, UP and c). Identification of a conductive zone, proved to be sulphide body, within the Mahakoshal group in the Gurharpahar area of Sidhi and Sonbhadra districts of MP and UP respectively. In the context of exploration for concealed uranium in the Gwalior basin, it is suggested to employ IP, resistivity, SP, gravity and magnetic methods for delineation of conductive zones like carbonaceous rocks, basement topography, including the graben like structures, fracture zone, geological boundaries and demarcation of the basin boundary. (author)

Indirect determination of the thermodynamic temperature of the copper point by a multi-fixed-point technique

Science.gov (United States)

Battuello, M.; Florio, M.; Girard, F.

2010-06-01

An indirect determination of the thermodynamic temperature of the fixed point of copper was made at INRIM by measuring four cells with a Si-based and an InGaAs-based precision radiation thermometer carrying approximated thermodynamic scales realized up to the Ag point. An average value TCu = 1357.840 K was found with a standard uncertainty of 0.047 K. A consequent (T - T90)Cu value of 70 mK can be derived which is 18 mK higher than, but consistent with, the presently available (T - T90)Cu as elaborated by the CCT-WG4.

System markets: Indirect network effects in action, or inaction?

NARCIS (Netherlands)

J.L.G. Binken (Jeroen)

2010-01-01

textabstractIn this dissertation, I empirically examine system markets up close. More specifically I examine indirect network effects, both demand-side and supply-side indirect network effects. Indirect network effects are the source of positive feedback in system markets, or so network effect

21 CFR 870.3640 - Indirect pacemaker generator function analyzer.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Indirect pacemaker generator function analyzer... Indirect pacemaker generator function analyzer. (a) Identification. An indirect pacemaker generator function analyzer is an electrically powered device that is used to determine pacemaker function or...

The hidden costs: Identification of indirect costs associated with acute gastrointestinal illness in an Inuit community

Science.gov (United States)

Vriezen, Rachael; Edge, Victoria L.; Ford, James; Wood, Michele; Harper, Sherilee

2018-01-01

Background Acute gastrointestinal illness (AGI) incidence and per-capita healthcare expenditures are higher in some Inuit communities as compared to elsewhere in Canada. Consequently, there is a demand for strategies that will reduce the individual-level costs of AGI; this will require a comprehensive understanding of the economic costs of AGI. However, given Inuit communities’ unique cultural, economic, and geographic contexts, there is a knowledge gap regarding the context-specific indirect costs of AGI borne by Inuit community members. This study aimed to identify the major indirect costs of AGI, and explore factors associated with these indirect costs, in the Inuit community of Rigolet, Canada, in order to develop a case-based context-specific study framework that can be used to evaluate these costs. Methods A mixed methods study design and community-based methods were used. Qualitative in-depth, group, and case interviews were analyzed using thematic analysis to identify and describe indirect costs of AGI specific to Rigolet. Data from two quantitative cross-sectional retrospective surveys were analyzed using univariable regression models to examine potential associations between predictor variables and the indirect costs. Results/Significance The most notable indirect costs of AGI that should be incorporated into cost-of-illness evaluations were the tangible costs related to missing paid employment and subsistence activities, as well as the intangible costs associated with missing community and cultural events. Seasonal cost variations should also be considered. This study was intended to inform cost-of-illness studies conducted in Rigolet and other similar research settings. These results contribute to a better understanding of the economic impacts of AGI on Rigolet residents, which could be used to help identify priority areas and resource allocation for public health policies and programs. PMID:29768456

Collage technique may provide new perspectives for Alzheimer patients by exploring messages from their inner world.

Science.gov (United States)

Meguro, Mitsue; Ishizaki, Junichi; Meguro, Kenichi

2009-01-01

Although the collage art technique has been introduced as a psychotherapeutic method, it has not been fully applied in dementia. To analyze characteristics of the collage articles produced by patients with Alzheimer's disease (AD). Twenty AD patients were asked to select and place several clippings as they wished. The MMSE was used for cognitive assessments. Simplification and poor organization in their articles were found. The themes of one patient were found to change according to behavior. We discussed the images of the articles, especially spiritual images in the early stage and family images in the later stage. We concluded that the collage technique could provide new perspectives for dementia patients by exploring messages from their inner world.

10 CFR 602.15 - Indirect cost limitations.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Indirect cost limitations. 602.15 Section 602.15 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.15 Indirect cost limitations. Awards issued under this part for conferences and...

Exploration of the speleotherapeutic potential through the cellular and molecular biology techniques

Directory of Open Access Journals (Sweden)

Munteanu Constantin

2011-02-01

Full Text Available Objective: Exploring the speleotherapy effects on morphology and physiology of dermal and pulmonary fibroblast obtained from Wistar rats tissue in normal conditions and after induction of experimental “astma” awareness with ovalbumin. Materials and methods: Before initiation of dermal and pulmonary fibroblast cultures, 60 of Wistar rats 75-100 g were divided into two groups: control and sensitized with ovalalbumin. 10 animals of each group were sent to Cacica and Dej salt mines and maintained in a speleotherapy regime. Another 10 animals in each group were monitored separately in INRMFB Biobase . Dermal and pulmonary fibroblast cultures were initiated by enzymatic techniques from appropriate tissue taken of each group Wistar rats. Morphological monitoring was done by phase contast microscopy; biochemical and molecular changes of cultures obtained from animals treated speleothropic compared to control, was experimental establised by electrophoresis and Western Blotting techniques.Results: Experimental data revealed the expression of several proteins after the speleotherapeutic treatment. These data were analysed compared with control, using a specific software.Conclusions: Speleotherapeutic treatment of Wistar rats caused significant differences in morphology and protein expression of dermal and pulmonary fibroblatst grown in the laboratory. These differences support the protective effects of speleotherapy compared with data obtained from animals untreated and sensitized with ovalbumin, having induced experimental asthma status.

10 CFR 605.16 - Indirect cost limitations.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Indirect cost limitations. 605.16 Section 605.16 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS THE OFFICE OF ENERGY RESEARCH FINANCIAL ASSISTANCE PROGRAM § 605.16 Indirect cost limitations. Awards issued under this part for conferences and scientific...

77 FR 41899 - Indirect Food Additives: Polymers

Science.gov (United States)

2012-07-17

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 177 [Docket No. FDA-2012-F-0031] Indirect Food Additives: Polymers AGENCY: Food and Drug Administration, HHS. ACTION... CFR part 177 is amended as follows: PART 177--INDIRECT FOOD ADDITIVES: POLYMERS 0 1. The authority...

Facilitating the indirect detection of genomic DNA in an electrochemical DNA biosensor using magnetic nanoparticles and DNA ligase

Directory of Open Access Journals (Sweden)

Roozbeh Hushiarian

2015-12-01

This technique was found to be reliably repeatable. The indirect detection of genomic DNA using this method is significantly improved and showed high efficiency in small amounts of samples with the detection limit of 5.37 × 10−14 M.

Indirect inference with time series observed with error

DEFF Research Database (Denmark)

Rossi, Eduardo; Santucci de Magistris, Paolo

estimation. We propose to solve this inconsistency by jointly estimating the nuisance and the structural parameters. Under standard assumptions, this estimator is consistent and asymptotically normal. A condition for the identification of ARMA plus noise is obtained. The proposed methodology is used......We analyze the properties of the indirect inference estimator when the observed series are contaminated by measurement error. We show that the indirect inference estimates are asymptotically biased when the nuisance parameters of the measurement error distribution are neglected in the indirect...... to estimate the parameters of continuous-time stochastic volatility models with auxiliary specifications based on realized volatility measures. Monte Carlo simulations shows the bias reduction of the indirect estimates obtained when the microstructure noise is explicitly modeled. Finally, an empirical...

Large and abundant flowers increase indirect costs of corollas: a study of coflowering sympatric Mediterranean species of contrasting flower size.

Science.gov (United States)

Teixido, Alberto L; Valladares, Fernando

2013-09-01

Large floral displays receive more pollinator visits but involve higher production and maintenance costs. This can result in indirect costs which may negatively affect functions like reproductive output. In this study, we explored the relationship between floral display and indirect costs in two pairs of coflowering sympatric Mediterranean Cistus of contrasting flower size. We hypothesized that: (1) corolla production entails direct costs in dry mass, N and P, (2) corollas entail significant indirect costs in terms of fruit set and seed production, (3) indirect costs increase with floral display, (4) indirect costs are greater in larger-flowered sympatric species, and (5) local climatic conditions influence indirect costs. We compared fruit set and seed production of petal-removed flowers and unmanipulated control flowers and evaluated the influence of mean flower number and mean flower size on relative fruit and seed gain of petal-removed and control flowers. Fruit set and seed production were significantly higher in petal-removed flowers in all the studied species. A positive relationship was found between relative fruit gain and mean individual flower size within species. In one pair of species, fruit gain was higher in the large-flowered species, as was the correlation between fruit gain and mean number of open flowers. In the other pair, the correlation between fruit gain and mean flower size was also higher in the large-flowered species. These results reveal that Mediterranean environments impose significant constraints on floral display, counteracting advantages of large flowers from the pollination point of view with increased indirect costs of such flowers.

The effect of feeding on CO2 production and energy expenditure in ponies measured by indirect calorimetry and the 13C-bicarbonate technique.

Science.gov (United States)

Jensen, R B; Kyrstein, T D; Junghans, P; Tauson, A H

2015-11-01

Energy expenditure (EE) can be estimated based on respiratory gas exchange measurements, traditionally done in respiration chambers by indirect calorimetry (IC). However, the (13)C-bicarbonate technique ((13)C-BT) might be an alternative minimal invasive method for estimation of CO(2) production and EE in the field. In this study, four Shetland ponies were used to explore the effect of feeding on CO(2) production and EE measured simultaneously by IC and (13)C-BT. The ponies were individually housed in respiration chambers and received either a single oral or intravenous (IV) bolus dose of (13)C-labelled sodium bicarbonate (NaH(13)CO(3)). The ponies were fed haylage 3 h before (T(-3)), simultaneously with (T(0)) or 3 h after (T(+3)) administration of (13)C-bicarbonate. The CO(2) produced and O(2) consumed by the ponies were measured for 6 h with both administration routes of (13)C-bicarbonate at the three different feeding times. Feeding time affected the CO(2) production (P<0.001) and O(2) consumption (P<0.001), but not the respiratory quotient (RQ) measured by IC. The recovery factor (RF) of (13)C in breath CO(2) was affected by feeding time (P<0.01) and three different RF were used in the calculation of CO(2) production measured by 13C-BT. An average RQ was used for the calculations of EE. There was no difference between IC and (13)C-BT for estimation of CO(2) production. An effect of feeding time (P<0.001) on the estimated EE was found, with higher EE when feed was offered (T(0) and T(+3)) compared with when no feed was available (T -3) during measurements. In conclusion, this study showed that feeding time affects the RF and measurements of CO(2) production and EE. This should be considered when the (13)C-BT is used in the field. IV administration of (13)C-bicarbonate is recommended in future studies with horses to avoid complex (13)C enrichment-time curves with maxima and shoulders as observed in several experiments with oral administration of (13)C-bicarbonate.

Tears of the Supraspinatus Tendon: Assessment with Indirect Magnetic Resonance Arthrography in 67 Patients with Arthroscopic Correlation

International Nuclear Information System (INIS)

Dyck, P. van; Gielen, J.L.; Parizel, P.M.

2009-01-01

Background: Magnetic resonance (MR) arthrography is generally regarded as the gold standard for shoulder imaging. As an alternative to direct MR arthrography, the less invasive indirect MR arthrography technique was proposed, offering logistic advantages because fluoroscopic or ultrasonographic guidance for joint injection is not required. Purpose: To assess the diagnostic performance of indirect MR arthrography in the diagnosis of full- and partial-thickness supraspinatus tears in a symptomatic population. Material and Methods: Two radiologists with different levels of experience independently and retrospectively interpreted indirect MR (1.5T) arthrograms of the shoulder obtained in 67 symptomatic patients who underwent subsequent arthroscopy. On MR, the supraspinatus tendon was evaluated for full- or partial-thickness tear. With arthroscopy as the standard of reference, sensitivity, specificity, and diagnostic accuracy of indirect MR arthrography in the detection of full- and partial-thickness tears of the supraspinatus tendon was calculated. Kappa (κ) statistics were used for the assessment of the agreement between arthroscopic and imaging findings and for the assessment of interobserver agreement. Results: For full-thickness tears of the supraspinatus tendon, sensitivities, specificities, and accuracies exceeded 90% for both observers, with excellent interobserver agreement (κ = 0.910). For partial-thickness tears, sensitivities (38-50%) and accuracies (76-78%) were poor for both reviewers, and interobserver agreement was moderate (κ = 0.491). Discrepancies between MR diagnosis and arthroscopy were predominantly observed with small partial-thickness tears. Conclusion: Indirect MR arthrography is highly accurate in the diagnosis of full-thickness rotator cuff tears. However, the diagnosis of partial-thickness tears with indirect MR arthrography remains faulty, because exact demarcation of degenerative change and partial rupture is difficult. On the basis of

Tears of the Supraspinatus Tendon: Assessment with Indirect Magnetic Resonance Arthrography in 67 Patients with Arthroscopic Correlation

Energy Technology Data Exchange (ETDEWEB)

Dyck, P. van; Gielen, J.L.; Parizel, P.M. (Dept. of Radiology, Univ. Hospital Antwerp and Univ. of Antwerp, Antwerp (Belgium)) (and others)

2009-11-15

Background: Magnetic resonance (MR) arthrography is generally regarded as the gold standard for shoulder imaging. As an alternative to direct MR arthrography, the less invasive indirect MR arthrography technique was proposed, offering logistic advantages because fluoroscopic or ultrasonographic guidance for joint injection is not required. Purpose: To assess the diagnostic performance of indirect MR arthrography in the diagnosis of full- and partial-thickness supraspinatus tears in a symptomatic population. Material and Methods: Two radiologists with different levels of experience independently and retrospectively interpreted indirect MR (1.5T) arthrograms of the shoulder obtained in 67 symptomatic patients who underwent subsequent arthroscopy. On MR, the supraspinatus tendon was evaluated for full- or partial-thickness tear. With arthroscopy as the standard of reference, sensitivity, specificity, and diagnostic accuracy of indirect MR arthrography in the detection of full- and partial-thickness tears of the supraspinatus tendon was calculated. Kappa (kappa) statistics were used for the assessment of the agreement between arthroscopic and imaging findings and for the assessment of interobserver agreement. Results: For full-thickness tears of the supraspinatus tendon, sensitivities, specificities, and accuracies exceeded 90% for both observers, with excellent interobserver agreement (kappa = 0.910). For partial-thickness tears, sensitivities (38-50%) and accuracies (76-78%) were poor for both reviewers, and interobserver agreement was moderate (kappa = 0.491). Discrepancies between MR diagnosis and arthroscopy were predominantly observed with small partial-thickness tears. Conclusion: Indirect MR arthrography is highly accurate in the diagnosis of full-thickness rotator cuff tears. However, the diagnosis of partial-thickness tears with indirect MR arthrography remains faulty, because exact demarcation of degenerative change and partial rupture is difficult. On the

Application of uranium exploration data and techniques in environmental studies. Proceedings of a technical committee meeting held in Vienna, 9-12 November 1993

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-10-01

Exploration for mineral commodities, uranium included normally utilizes extensive, systematic geophysical and geochemical surveys covering very large areas, often entire countries. This information represents a great wealth of data that could be used to produce baseline information for environmental studies and monitoring. It is with this appreciation that IAEA convened a Technical Committee meeting with the purpose of bringing together experts in uranium exploration, geophysics and geochemistry to discuss and exchange information on the benefits of past exploration data and commonly applied techniques in environmental studies. The meeting on the Use of Uranium Exploration Data and Techniques in Environmental Studies was attended by 44 participants from 23 countries and one international organization. Thirty-two papers covering case histories on the use of old uranium exploration data to prepare exposure dose rate and radon potential maps, the use of airborne gamma ray spectrometric systems to monitor nuclear power plants and nuclear fuel cycle facilities, and the use of similar systems in response to emergency measures in the case of accidental releases were presented. Refs, figs and tabs.

Application of uranium exploration data and techniques in environmental studies. Proceedings of a technical committee meeting held in Vienna, 9-12 November 1993

International Nuclear Information System (INIS)

1995-10-01

Exploration for mineral commodities, uranium included normally utilizes extensive, systematic geophysical and geochemical surveys covering very large areas, often entire countries. This information represents a great wealth of data that could be used to produce baseline information for environmental studies and monitoring. It is with this appreciation that IAEA convened a Technical Committee meeting with the purpose of bringing together experts in uranium exploration, geophysics and geochemistry to discuss and exchange information on the benefits of past exploration data and commonly applied techniques in environmental studies. The meeting on the Use of Uranium Exploration Data and Techniques in Environmental Studies was attended by 44 participants from 23 countries and one international organization. Thirty-two papers covering case histories on the use of old uranium exploration data to prepare exposure dose rate and radon potential maps, the use of airborne gamma ray spectrometric systems to monitor nuclear power plants and nuclear fuel cycle facilities, and the use of similar systems in response to emergency measures in the case of accidental releases were presented. Refs, figs and tabs

INDIRECT COMMUNICATION AND FACE-SAVING FACTOR: FROM THEORY TO PRACTICE

Directory of Open Access Journals (Sweden)

ROZINA GUNTA

2015-01-01

Full Text Available The paper analyses silence as a non-linguistic resource for conveying indirect communicative acts. Applied linguists assert that the use of silence for communicative purposes might be determined by several categories of factors, the face-saving factor being one of them. So far, much research has been done to determine how the speakers of different languages use silence; however, only limited research on silence as a strategy for face saving can be identified. Thus, the current investigation was undertaken to explore the relationship between the face-saving factor and non-verbal communication where silence as a strategy for indirect interaction was applied. Within this framework, the study dealt with the analysis of silence as a workable strategy that is often adopted in non-native speakers’ communication in English. With this purpose, four focus groups of non-native speakers (NNSs of English in Latvia were selected. The investigation was approached from the perspective of qualitative research, and it applied a case study as the research method. The study has acquired two types of findings. First, when the target language is applied for interactional purposes, NNSs of the English language are influenced by cognitive and pragma-social factors. Second, when NNSs adopt both aspects of language, i.e., verbal and non-verbal, for interaction, the strategy depends on numerous factors, silence being one of them. The study has demonstrated that silence is often applied to communicate information indirectly, and it is frequently used as a face-saving strategy in interaction in the target language. The use of silence as a communicative strategy depends on numerous factors in different non-native language users’ settings and varies according to the focus of interactional purposes.

Collage technique may provide new perspectives for Alzheimer patients by exploring messages from their inner world

Directory of Open Access Journals (Sweden)

Mitsue Meguro

Full Text Available Abstract Although the collage art technique has been introduced as a psychotherapeutic method, it has not been fully applied in dementia. Objectives: To analyze characteristics of the collage articles produced by patients with Alzheimer's disease (AD. Methods: Twenty AD patients were asked to select and place several clippings as they wished. The MMSE was used for cognitive assessments. Results: Simplification and poor organization in their articles were found. The themes of one patient were found to change according to behavior. We discussed the images of the articles, especially spiritual images in the early stage and family images in the later stage. Conclusions: We concluded that the collage technique could provide new perspectives for dementia patients by exploring messages from their inner world.

PathlinesExplorer — Image-based exploration of large-scale pathline fields

KAUST Repository

Nagoor, Omniah H.

2015-10-25

PathlinesExplorer is a novel image-based tool, which has been designed to visualize large scale pathline fields on a single computer [7]. PathlinesExplorer integrates explorable images (EI) technique [4] with order-independent transparency (OIT) method [2]. What makes this method different is that it allows users to handle large data on a single workstation. Although it is a view-dependent method, PathlinesExplorer combines both exploration and modification of visual aspects without re-accessing the original huge data. Our approach is based on constructing a per-pixel linked list data structure in which each pixel contains a list of pathline segments. With this view-dependent method, it is possible to filter, color-code, and explore large-scale flow data in real-time. In addition, optimization techniques such as early-ray termination and deferred shading are applied, which further improves the performance and scalability of our approach.

Clinical e radiographic sucess of indirect pulp capping with partial excavation of demineralization dentin in primary posterior teeth

Directory of Open Access Journals (Sweden)

Roberta Francisca Martins de Castro

2009-10-01

Full Text Available Objective: To assess the outcome of the indirect pulp capping technique after incomplete excavation of the demineralized dentin in primary molars of patients treated in the period from 2004 to 2006.Methods: Sample consisted of 81 teeth of 36 patients aged from 1-to-8 year-old. Clinical and radiographic inclusion criteria, as well as criteria of the success of the evaluated treatments were established.Results: There were four (4.9% failures and 77 (95.1% successful treatments. Treatment failure occurred in three girls and in one boy, and no statistically significant difference (p=0.341 was found. Twenty three teeth were treated with resin-modified glass-ionomer cement and 58 with composite resin, of which 22 and 55, respectively, showed successful results. There was no statistically significant difference between restorative materials used (p=0.877. As regards the studied age group, patients aged from 1 to 4 years showed a significantly lower success rate when compared with 5-8 year-old children (p = 0.0428. Conclusion: The results suggest that the indirect pulp capping technique after incomplete excavation of demineralized dentin is a reliable technique to be adopted in deep lesions of primary teeth.

Negotiating the Rules of Engagement: Exploring Perceptions of Dance Technique Learning through Bourdieu's Concept of "Doxa"

Science.gov (United States)

Rimmer, Rachel

2017-01-01

This article presents the findings from a focus group discussion conducted with first year undergraduate dance students in March 2015. The focus group concluded a cycle of action research during which the researcher explored the use of enquiry-based learning approaches to teaching dance technique in higher education. Grounded in transformative and…

Forensic electrochemistry: indirect electrochemical sensing of the components of the new psychoactive substance "Synthacaine".

Science.gov (United States)

Cumba, Loanda R; Kolliopoulos, Athanasios V; Smith, Jamie P; Thompson, Paul D; Evans, Peter R; Sutcliffe, Oliver B; do Carmo, Devaney R; Banks, Craig E

2015-08-21

"Synthacaine" is a New Psychoactive Substance which is, due to its inherent psychoactive properties, reported to imitate the effects of cocaine and is therefore consequently branded as "legal cocaine". The only analytical approach reported to date for the sensing of "Synthacaine" is mass spectrometry. In this paper, we explore and evaluate a range of potential analytical techniques for its quantification and potential use in the field screening "Synthacaine" using Raman spectroscopy, presumptive (colour) testing, High Performance Liquid Chromatography (HPLC) and electrochemistry. HPLC analysis of street samples reveals that "Synthacaine" comprises a mixture of methiopropamine (MPA) and 2-aminoindane (2-AI). Raman spectroscopy and presumptive (colour) tests, the Marquis, Mandelin, Simon's and Robadope test, are evaluated towards a potential in-the-field screening approach but are found to not be able to discriminate between the two when they are both present in the same sample, as is the case in the real street samples. We report for the first time a novel indirect electrochemical protocol for the sensing of MPA and 2-AI which is independently validated in street samples with HPLC. This novel electrochemical approach based upon one-shot disposable cost effective screen-printed graphite macroelectrodes holds potential for in-the-field screening for "Synthacaine".

Peer-to-peer shadowing as a technique for the development of nurse middle managers clinical leadership : an explorative study

NARCIS (Netherlands)

Pieterbas Lalleman; G.A.C. Smid; J. Rasiah; J. Bouma; M.J. Schuurmans

2017-01-01

The purpose of this study was to explore the experiences and impact of peer-to-peer shadowing as a technique to develop nurse middle managers’ clinical leadership practices. A qualitative descriptive study was conducted to gain insight into the experiences of nurse middle managers using

Indirect Taxes in Romania – an Econometric Analysis

Directory of Open Access Journals (Sweden)

Daniela Penu

2016-03-01

Full Text Available Indirect taxes have a significant weight in the GDP. Statistical data reveals that the new states that joined the EU in its funding sources to the greatest extent through indirect taxes. They reveal, on the one hand, reducing the tax burden on the producer, and on the other hand, the difficulty faced by the country in direct tax collection, but also some problems of social nature. This article proposes an econometric analysis of the relationship between indirect taxes and household final consumption expenditure.

Analyzing indirect effects in cluster randomized trials. The effect of estimation method, number of groups and group sizes on accuracy and power.

Directory of Open Access Journals (Sweden)

Joop eHox

2014-02-01

Full Text Available Cluster randomized trials assess the effect of an intervention that is carried out at the group or cluster level. Ajzen’s theory of planned behaviour is often used to model the effect of the intervention as an indirect effect mediated in turn by attitude, norms and behavioural intention. Structural equation modelling (SEM is the technique of choice to estimate indirect effects and their significance. However, this is a large sample technique, and its application in a cluster randomized trial assumes a relatively large number of clusters. In practice, the number of clusters in these studies tends to be relatively small, e.g. much less than fifty. This study uses simulation methods to find the lowest number of clusters needed when multilevel SEM is used to estimate the indirect effect. Maximum likelihood estimation is compared to Bayesian analysis, with the central quality criteria being accuracy of the point estimate and the confidence interval. We also investigate the power of the test for the indirect effect. We conclude that Bayes estimation works well with much smaller cluster level sample sizes such as 20 cases than maximum likelihood estimation; although the bias is larger the coverage is much better. When only 5 to 10 clusters are available per treatment condition even with Bayesian estimation problems occur.

The power of indirect social ties

OpenAIRE

Zuo, Xiang; Blackburn, Jeremy; Kourtellis, Nicolas; Skvoretz, John; Iamnitchi, Adriana

2014-01-01

While direct social ties have been intensely studied in the context of computer-mediated social networks, indirect ties (e.g., friends of friends) have seen little attention. Yet in real life, we often rely on friends of our friends for recommendations (of good doctors, good schools, or good babysitters), for introduction to a new job opportunity, and for many other occasional needs. In this work we attempt to 1) quantify the strength of indirect social ties, 2) validate it, and 3) empiricall...

Two distinct neural mechanisms underlying indirect reciprocity.

Science.gov (United States)

Watanabe, Takamitsu; Takezawa, Masanori; Nakawake, Yo; Kunimatsu, Akira; Yamasue, Hidenori; Nakamura, Mitsuhiro; Miyashita, Yasushi; Masuda, Naoki

2014-03-18

Cooperation is a hallmark of human society. Humans often cooperate with strangers even if they will not meet each other again. This so-called indirect reciprocity enables large-scale cooperation among nonkin and can occur based on a reputation mechanism or as a succession of pay-it-forward behavior. Here, we provide the functional and anatomical neural evidence for two distinct mechanisms governing the two types of indirect reciprocity. Cooperation occurring as reputation-based reciprocity specifically recruited the precuneus, a region associated with self-centered cognition. During such cooperative behavior, the precuneus was functionally connected with the caudate, a region linking rewards to behavior. Furthermore, the precuneus of a cooperative subject had a strong resting-state functional connectivity (rsFC) with the caudate and a large gray matter volume. In contrast, pay-it-forward reciprocity recruited the anterior insula (AI), a brain region associated with affective empathy. The AI was functionally connected with the caudate during cooperation occurring as pay-it-forward reciprocity, and its gray matter volume and rsFC with the caudate predicted the tendency of such cooperation. The revealed difference is consistent with the existing results of evolutionary game theory: although reputation-based indirect reciprocity robustly evolves as a self-interested behavior in theory, pay-it-forward indirect reciprocity does not on its own. The present study provides neural mechanisms underlying indirect reciprocity and suggests that pay-it-forward reciprocity may not occur as myopic profit maximization but elicit emotional rewards.

Preschool children's behavioral tendency toward social indirect reciprocity.

Directory of Open Access Journals (Sweden)

Mayuko Kato-Shimizu

Full Text Available Social indirect reciprocity seems to be crucial in enabling large-scale cooperative networks among genetically unrelated individuals in humans. However, there are relatively few studies on social indirect reciprocity in children compared to adults. Investigating whether young children have a behavioral tendency toward social indirect reciprocity will help us understand how and when the fundamental ability to form cooperative relationships among adults is acquired. Using naturalistic observation at a nursery school, this study examined whether 5- to 6-year-olds show a behavioral tendency to engage in social indirect reciprocity in response to their peers' prosocial behavior toward a third party. The results revealed that bystander children tended to display prosocial behavior toward their peers more frequently after observing these peers' prosocial behavior toward third-party peers, compared with control situations; this suggests that 5- to 6-year-olds may have an essential behavioral tendency to establish social indirect reciprocity when interacting with peers in their daily lives. In addition, bystanders tended to display affiliative behavior after observing focal children's prosocial behavior. In other words, observing peers' prosocial behavior toward third-party peers evoked bystanders' positive emotions toward the helpers. Considering both the present results and previous findings, we speculate that in preschoolers, such positive emotions might mediate the increase in the bystander's prosocial behavior toward the helper. In addition, an intuitional emotional process plays an important role in the preschooler's behavioral tendency toward social indirect reciprocity in natural interactions with peers.

Preschool children's behavioral tendency toward social indirect reciprocity.

Science.gov (United States)

Kato-Shimizu, Mayuko; Onishi, Kenji; Kanazawa, Tadahiro; Hinobayashi, Toshihiko

2013-01-01

Social indirect reciprocity seems to be crucial in enabling large-scale cooperative networks among genetically unrelated individuals in humans. However, there are relatively few studies on social indirect reciprocity in children compared to adults. Investigating whether young children have a behavioral tendency toward social indirect reciprocity will help us understand how and when the fundamental ability to form cooperative relationships among adults is acquired. Using naturalistic observation at a nursery school, this study examined whether 5- to 6-year-olds show a behavioral tendency to engage in social indirect reciprocity in response to their peers' prosocial behavior toward a third party. The results revealed that bystander children tended to display prosocial behavior toward their peers more frequently after observing these peers' prosocial behavior toward third-party peers, compared with control situations; this suggests that 5- to 6-year-olds may have an essential behavioral tendency to establish social indirect reciprocity when interacting with peers in their daily lives. In addition, bystanders tended to display affiliative behavior after observing focal children's prosocial behavior. In other words, observing peers' prosocial behavior toward third-party peers evoked bystanders' positive emotions toward the helpers. Considering both the present results and previous findings, we speculate that in preschoolers, such positive emotions might mediate the increase in the bystander's prosocial behavior toward the helper. In addition, an intuitional emotional process plays an important role in the preschooler's behavioral tendency toward social indirect reciprocity in natural interactions with peers.

A Comparative study for striatal-direct and -indirect pathway neurons to DA depletion-induced lesion in a PD rat model.

Science.gov (United States)

Zheng, Xuefeng; Wu, Jiajia; Zhu, Yaofeng; Chen, Si; Chen, Zhi; Chen, Tao; Huang, Ziyun; Wei, Jiayou; Li, Yanmei; Lei, Wanlong

2018-04-16

Striatal-direct and -indirect Pathway Neurons showed different vulnerability in basal ganglia disorders. Therefore, present study aimed to examine and compare characteristic changes of densities, protein and mRNA levels of soma, dendrites, and spines between striatal-direct and -indirect pathway neurons after DA depletion by using immunohistochemistry, Western blotting, real-time PCR and immunoelectron microscopy techniques. Experimental results showed that: 1) 6OHDA-induced DA depletion decreased the soma density of striatal-direct pathway neurons (SP+), but no significant changes for striatal-indirect pathway neurons (ENK+). 2) DA depletion resulted in a decline of dendrite density for both striatal-direct (D1+) and -indirect (D2+) pathway neurons, and D2+ dendritic density declined more obviously. At the ultrastructure level, the densities of D1+ and D2+ dendritic spines reduced in the 6OHDA groups compared with their control groups, but the density of D2+ dendritic spines reduced more significant than that of D1. 3) Striatal DA depletion down-regulated protein and mRNA expression levels of SP and D1, on the contrary, ENK and D2 protein and mRNA levels of indirect pathway neurons were up-regulated significantly. Present results suggested that indirect pathway neurons be more sensitive to 6OHDA-induced DA depletion. Copyright © 2018 Elsevier Ltd. All rights reserved.

Separating astrophysical sources from indirect dark matter signals

Science.gov (United States)

Siegal-Gaskins, Jennifer M.

2015-01-01

Indirect searches for products of dark matter annihilation and decay face the challenge of identifying an uncertain and subdominant signal in the presence of uncertain backgrounds. Two valuable approaches to this problem are (i) using analysis methods which take advantage of different features in the energy spectrum and angular distribution of the signal and backgrounds and (ii) more accurately characterizing backgrounds, which allows for more robust identification of possible signals. These two approaches are complementary and can be significantly strengthened when used together. I review the status of indirect searches with gamma rays using two promising targets, the Inner Galaxy and the isotropic gamma-ray background. For both targets, uncertainties in the properties of backgrounds are a major limitation to the sensitivity of indirect searches. I then highlight approaches which can enhance the sensitivity of indirect searches using these targets. PMID:25304638

Geochemical exploration for uranium

International Nuclear Information System (INIS)

1988-01-01

This Technical Report is designed mainly to introduce the methods and techniques of uranium geochemical exploration to exploration geologists who may not have had experience with geochemical exploration methods in their uranium programmes. The methods presented have been widely used in the uranium exploration industry for more than two decades. The intention has not been to produce an exhaustive, detailed manual, although detailed instructions are given for a field and laboratory data recording scheme and a satisfactory analytical method for the geochemical determination of uranium. Rather, the intention has been to introduce the concepts and methods of uranium exploration geochemistry in sufficient detail to guide the user in their effective use. Readers are advised to consult general references on geochemical exploration to increase their understanding of geochemical techniques for uranium

Indirect search for dark matter with AMS

International Nuclear Information System (INIS)

Goy, Corinne

2006-01-01

This document summarises the potential of AMS in the indirect search for Dark Matter. Observations and cosmology indicate that the Universe may include a large amount of Dark Matter of unknown nature. A good candidate is the Ligthest Supersymmetric Particle in R-Parity conserving models. AMS offers a unique opportunity to study Dark Matter indirect signature in three spectra: gamma, antiprotons and positrons

Indirect transformation in reciprocal space: desmearing of small-angle scattering data from partially ordered systems

International Nuclear Information System (INIS)

Glatter, O.; Gruber, K.

1993-01-01

Indirect Fourier transformation is a widely used technique for the desmearing of instrumental broadening effects, for data smoothing and for Fourier transformation of small-angle scattering data. This technique, however, can only be applied to scattering curves with a band-limited Fourier transform, i.e. separated and noninteracting scattering centers. It can therefore not be used for scattering data from partially ordered systems. In this paper, a modified technique for partially ordered systems working in reciprocal space is presented. A peak-recognition technique allows its application to scattering functions with narrow peaks, such as the scattering functions of layered systems like lamellar stacks or strongly interacting particles. Arbitrary geometry effects and wavelength effects can be corrected. Examples of simulations show the merits and limits of this new method. One example shows its applicability to real data. (orig.)

A review of Indirect Matrix Converter Topologies

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Salem Rahmani

2015-08-01

Full Text Available Abstract—Matrix Converter (MC is a modern direct AC/AC electrical power converter without dc-link capacitor. MC is operated in four quadrant, assuring a control of the output voltage, amplitude and frequency. The matrix converter has recently attracted significant attention among researchers and it has become increasing attractive for applications of wind energy conversion, military power supplies, induction motor drives, etc. Recently, different MC topologies have been proposed and developed which have their own advantages and disadvantages. Matrix converter can be classified as direct and indirect structures. The direct one has been elaborated in previous work. In this paper the indirect MCs are reviewed. Different characteristics of the indirect MC topologies are mentioned to show the strengths and weaknesses of such converter topologies.

Direct and indirect measurement of the magnetocaloric effect in bulk and nanostructured Ni-Mn-In Heusler alloy

Science.gov (United States)

Ghahremani, Mohammadreza; Aslani, Amir; Hosseinnia, Marjan; Bennett, Lawrence H.; Della Torre, Edward

2018-05-01

A systematic study of the magnetocaloric effect of a Ni51Mn33.4In15.6 Heusler alloy converted to nanoparticles via high energy ball-milling technique in the temperature range of 270 to 310 K has been performed. The properties of the particles were characterized by x-ray diffraction, electron microscopy, and magnetometer techniques. Isothermal magnetic field variation of magnetization exhibits field hysteresis in bulk Ni51Mn33.4In15.6 alloy across the martensitic transition which significantly lessened in the nanoparticles. The magnetocaloric effects of the bulk and nanoparticle samples were measured both with direct method, through our state of the art direct test bed apparatus with controllability over the applied fields and temperatures, as well as an indirect method through Maxwell and thermodynamic equations. In direct measurements, nanoparticle sample's critical temperature decreased by 6 K, but its magnetocaloric effect enhanced by 17% over the bulk counterpart. Additionally, when comparing the direct and indirect magnetocaloric curves, the direct method showed 14% less adiabatic temperature change in the bulk and 5% less adiabatic temperature change in the nanostructured sample.

Parental mentalizing as an indirect link between attachment anxiety and parenting satisfaction.

Science.gov (United States)

Burkhart, Margaret L; Borelli, Jessica L; Rasmussen, Hannah F; Brody, Robin; Sbarra, David A

2017-03-01

Attachment anxiety in parents is associated with lower quality parent-child relationships. An inhibited capacity to reflect on children's mental states, referred to as prementalizing, may reduce the pleasure parents derive from their relationships. In the current study, we explored the associations among attachment anxiety, prementalizing, and parenting satisfaction in two groups of participants randomly assigned either to reflect on a positive memory with their child (n = 150) or to reflect on a positive memory not involving their child (n = 150). Narratives were evaluated for positive content using two metrics: coder-rated positivity and frequency of positive emotion words. Results revealed that self-reported prementalizing operated indirectly to link attachment anxiety and self-reported parenting satisfaction for both groups. However, prementalizing only served as an indirect link between attachment anxiety and coded measures of positivity among participants who reflected on parenting experiences, suggesting the specificity of prementalizing in linking attachment anxiety and reduced positivity in the parenting role. The results have implications for understanding influences of attachment and mentalization on parents' perception of parent-child relationship quality. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Indirect Control for Demand Side Management – A Conceptual Introduction

DEFF Research Database (Denmark)

Heussen, Kai; You, Shi; Biegel, Benjamin

2012-01-01

The concept of “indirect control” has become a relevant discussion term in relation to activation distributed and small-scale demand and generation units to provide resources for power system balancing. The term and its association with price signals has, however caused some confusion as to its...... correct definition, either as a control or a market concept. This paper aims to provide a conceptual introduction to "indirect control" for management of small and distributed demand side resources. A review of control concepts and an analysis of "indirectness" features are provided to create a framework...... for systematic classification of indirect control strategies. The concepts developed then enable a discussion of control performance and valuation of direct- and indirect control strategies....

The Influence of Direct and Indirect Speech on Source Memory

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Anita Eerland

2018-02-01

Full Text Available People perceive the same situation described in direct speech (e.g., John said, “I like the food at this restaurant” as more vivid and perceptually engaging than described in indirect speech (e.g., John said that he likes the food at the restaurant. So, if direct speech enhances the perception of vividness relative to indirect speech, what are the effects of using indirect speech? In four experiments, we examined whether the use of direct and indirect speech influences the comprehender’s memory for the identity of the speaker. Participants read a direct or an indirect speech version of a story and then addressed statements to one of the four protagonists of the story in a memory task. We found better source memory at the level of protagonist gender after indirect than direct speech (Exp. 1–3. When the story was rewritten to make the protagonists more distinctive, we also found an effect of speech type on source memory at the level of the individual, with better memory after indirect than direct speech (Exp. 3–4. Memory for the content of the story, however, was not influenced by speech type (Exp. 4. While previous research showed that direct speech may enhance memory for how something was said, we conclude that indirect speech enhances memory for who said what.

The tobacco industry's accounts of refining indirect tobacco advertising in Malaysia.

Science.gov (United States)

Assunta, M; Chapman, S

2004-12-01

To explore tobacco industry accounts of its use of indirect tobacco advertising and trademark diversification (TMD) in Malaysia, a nation with a reputation for having an abundance of such advertising. Systematic keyword and opportunistic website searches of formerly private tobacco industry internal documents made available through the Master Settlement Agreement. 132 documents relevant to the topic were reviewed. TMD efforts were created to advertise cigarettes after advertising restrictions on direct advertising were imposed in 1982. To build public credibility the tobacco companies set up small companies and projected them as entities independent of tobacco. Each brand selected an activity or event such as music, travel, fashion, and sports that best suited its image. RJ Reynolds sponsored music events to advertise its Salem brand while Philip Morris used Marlboro World of Sports since advertising restrictions prevented the use of the Marlboro man in broadcast media. Despite a ban on tobacco advertisements in the mass media, tobacco companies were the top advertisers in the country throughout the 1980s and 1990s. The media's dependence on advertising revenue and support from the ruling elite played a part in delaying efforts to ban indirect advertising. Advertising is crucial for the tobacco industry. When faced with an advertising ban they created ways to circumvent it, such as TMDs.

Role of electroweak radiation in predictions for dark matter indirect detection

Energy Technology Data Exchange (ETDEWEB)

Ali Cavasonza, Leila; Pellen, Mathieu; Kraemer, Michael [RWTH Aachen, Aachen (Germany)

2015-07-01

A very exciting challenge in particle and astroparticle physics is the exploration of the nature of dark matter. The evidences of the existence of dark matter are also the strongest phenomenological indications for physics beyond the Standard Model. A huge experimental effort is currently made at colliders and via astrophysical experiments to shed light on the nature of dark matter: dark matter may be produced at colliders or detected through direct and indirect detection experiments. The interplay and complementarity between these different approaches offers extraordinary opportunities to improve our understanding of the nature of dark matter or to set constraints on dark matter models. In indirect detection one searches for dark matter annihilation products, that produce secondary antimatter particles like positrons and antiprotons. Such antimatter particles propagate through the Galaxy and can be detected at Earth by astrophysical experiments. Particularly interesting is the importance of electroweak corrections to the predictions for the expected fluxes at Earth. The inclusion of EW radiation from the primary dark matter annihilation products can significantly affect the spectra of the secondary SM particles. The EW radiation can be described using fragmentation functions, as done for instance in QCD. We study the quality of this approximation in a simplified SUSY model and in a UED model.

Indirect reciprocity and the evolution of "moral signals"

Science.gov (United States)

Smead, Rory

2010-01-01

Signals regarding the behavior of others are an essential element of human moral systems and there are important evolutionary connections between language and large-scale cooperation. In particular, social communication may be required for the reputation tracking needed to stabilize indirect reciprocity. Additionally, scholars have suggested that the benefits of indirect reciprocity may have been important for the evolution of language and that social signals may have coevolved with large-scale cooperation. This paper investigates the possibility of such a coevolution. Using the tools of evolutionary game theory, we present a model that incorporates primitive "moral signaling" into a simple setting of indirect reciprocity. This model reveals some potential difficulties for the evolution of "moral signals." We find that it is possible for "moral signals" to evolve alongside indirect reciprocity, but without some external pressure aiding the evolution of a signaling system, such a coevolution is unlikely.

Epidemic spreading through direct and indirect interactions.

Science.gov (United States)

Ganguly, Niloy; Krueger, Tyll; Mukherjee, Animesh; Saha, Sudipta

2014-09-01

In this paper we study the susceptible-infected-susceptible epidemic dynamics, considering a specialized setting where popular places (termed passive entities) are visited by agents (termed active entities). We consider two types of spreading dynamics: direct spreading, where the active entities infect each other while visiting the passive entities, and indirect spreading, where the passive entities act as carriers and the infection is spread via them. We investigate in particular the effect of selection strategy, i.e., the way passive entities are chosen, in the spread of epidemics. We introduce a mathematical framework to study the effect of an arbitrary selection strategy and derive formulas for prevalence, extinction probabilities, and epidemic thresholds for both indirect and direct spreading. We also obtain a very simple relationship between the extinction probability and the prevalence. We pay special attention to preferential selection and derive exact formulas. The analysis reveals that an increase in the diversity in the selection process lowers the epidemic thresholds. Comparing the direct and indirect spreading, we identify regions in the parameter space where the prevalence of the indirect spreading is higher than the direct one.

An indecent proposal: the dual functions of indirect speech.

Science.gov (United States)

Chakroff, Aleksandr; Thomas, Kyle A; Haque, Omar S; Young, Liane

2015-01-01

People often use indirect speech, for example, when trying to bribe a police officer by asking whether there might be "a way to take care of things without all the paperwork." Recent game theoretic accounts suggest that a speaker uses indirect speech to reduce public accountability for socially risky behaviors. The present studies examine a secondary function of indirect speech use: increasing the perceived moral permissibility of an action. Participants report that indirect speech is associated with reduced accountability for unethical behavior, as well as increased moral permissibility and increased likelihood of unethical behavior. Importantly, moral permissibility was a stronger mediator of the effect of indirect speech on likelihood of action, for judgments of one's own versus others' unethical action. In sum, the motorist who bribes the police officer with winks and nudges may not only avoid public punishment but also maintain the sense that his actions are morally permissible. Copyright © 2014 Cognitive Science Society, Inc.

Exploring the Relationships Between Just-In-Time Technique and Manufacturing Performance: Empirical Evidence From Selected Nigerian Firms

OpenAIRE

Ph. D. John Kolade Obamiro

2009-01-01

This study explores the relationship between just-in-time technique and manufacturing performance of some selected Nigerian companies. Just-in time was considered to be an overall organisational phenomenon. Data were obtained through a structured questionnaire from a sample size of 300 knowledgeable employees to test the developed model and formulated hypotheses that cover both just-intime and the supporting infrastructures. Bivariate correlation analysis was used to test the three hypotheses...

Modification of a whole room indirect calorimeter for measurement of rapid changes in energy expenditure.

Science.gov (United States)

Sun, M; Reed, G W; Hill, J O

1994-06-01

Whole room indirect calorimeters are among the most accurate devices for measurement of human energy expenditure and have provided useful data about determinants of total daily energy expenditure. However, a limitation of whole room indirect calorimeters has been the inability to detect acute (usually calorimeter (respiratory chamber) to allow accurate measurement of energy expenditure over time periods as short as 1 min. The modifications involve changes in the system design and use of signal processing techniques. With these modifications, we can measure energy expenditure in 1-min intervals throughout the day. This allows accurate study of the acute effects of food, exercise, or drugs on energy expenditure in subjects moving freely inside the respiratory chamber. The ability to use respiratory chambers for these types of studies should improve our understanding of how body weight is regulated.

DIRECT AND INDIRECT SOMATIC EMBRYOGENESIS ON ARABICA COFFEE (Coffea arabica

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Meynarti Sari Dewi Ibrahim

2013-10-01

Full Text Available Propagation of Coffea arabica L. through direct and indirect somatic embryogenesis technique is promising for producing large number of coffee seedlings. The objectives of the research were to evaluate methods for direct and indirect somatic embryo-genesis induction of C. arabica var. Kartika. The explants were the youngest fully expanded leaves of arabica coffee. The evalu-ated medium was modified Murashige and Skoog (MS medium supplemented with a combination of 2.26 µM 2,4-D + 4.54 or 9.08 µM thidiazuron; 4.52 µM 2,4-D + 4.54 or 9.08 µM thidiazuron; or 9.04 µM 2,4-D + 9.08 µM thidiazuron. Both calli (100 mg and pre-embryos developed from the edge of leaf explants were subcultured into regeneration medium (half strength MS with modified vitamin, supplemented with kinetine 9.30 µM and adenine sulfate 40 mg L-1. The results showed coffee leaf explant cultured on medium containing 2.26 µM 2,4-D + 4.54 or 9.08 µM thidiazuron to induce direct somatic embriogenesis from explant, while that of 4.52 or 9.04 µM 2,4-D + 9.08 µM thidiazuron to induced indirect somatic embrio-genesis. The medium for calli induction from coffee by explants was medium supplemented with 4.52 or 9.04 µM 2,4-D in combination with 9.08 µM thidiazuron. On the other hand, the best medium for activation of induction of somatic embryos was MS medium supplemented with 9.04 µM 2,4-D + 9.08 µM thidiazuron. Based on this results, the first step for developing micropropagation for coffee has been resolved. The subsequent studies will be directed to evaluate agronomic performance of the derived planting materials.

The Indirect cost of illness in Africa

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Joses Muthuri Kirigia

2018-06-01

Full Text Available Background: The current study estimated (a the indirect costs associated with non-fatal disability and premature death across a wide range of diseases and health conditions in Africa in 2015 and (b the potential savings that could be accrued if countries were to meet the 3 health targets of the substainable development goal (SDG compared to the costs under the status quo. Methods: This study used the lost output or human capital approach to quantify the gross domestic product (GDP losses associated with the disability-adjusted-life-years (DALYs lost due to all causes by age group as well as by country economic classification (Group 1: 10 high/upper-middle income countries; Group 2: 17 lower-middle income countries; and Group 3: 27 low income countries. Results: The expected indirect cost of the 704,765,879 DALYs lost in Africa in 2015 was Int$ 2,983,187,560,197. Of this amount, 25.17%, 57.84% and 16.99% were incurred by the economies of the countries comprising Group 1, Group 2 and Group 3, respectively. Of the total continental indirect cost, 36.9%, 10.5%, 13.7%, 17.0%, 7.6%, 6.8% and 7.5% were associated with people aged 0-4, 5-14, 15-29, 30-49, 50-59, 60-69 and 70 years or older, respectively. Most of the total indirect cost (56.61% was attributable to maternal conditions, AIDS, tuberculosis (TB, malaria, neglected tropicald diseases (NTDs, non-communicable diseases and traffic injuries. Approximately half (47% of this cost could be avoided (or saved every year if the 3 (health targets of the SDG were fully met. Conclusion: The study estimated the total indirect cost of illness due to all causes by age group and country economic classification. The annual indirect cost is substantial. The findings contained in this paper suggest that health system strengthening should focus on both rich and poor countries, people of all ages and specific disease categories.

Selection for components of complex characteristics - indirect selection

International Nuclear Information System (INIS)

Haensel, H.

1984-01-01

A hierarchy of complexity exists in plant characteristics. The efficiency of indirect selection for a complex characteristic by a sub-trait depends on the heritability of the complex characteristic (hsub(c)), the heritability of the sub-trait (hsub(s)), and the genotypic correlation between sub-trait and complex characteristic (rsub(s.c)). In 1961 hsub(s)Xrsub(s.c)>hsub(c) was postulated, when indirect selection becomes more efficient than direct selection. Numerical examples for this relationship are given and a table for indirect selection for yield in wheat is elaborated. Efficiency ranking of sub-traits in indirect selection may change with climate, conditions of cultivation, the level of other sub-traits, the level of the complex characteristic already reached by breeding, and the breeding material. An example shows that regression analysis for different sub-traits on the same complex characteristic, and an estimation of the differences of the within - and the between - variety slopes, may help to select the more efficient sub-trait. In another example, where simultaneous selection was made for two polygenic characteristics, one directly and the other indirectly by two sub-traits, less than half the F 5 -lines had to be continued, when using the more efficient sub-trait. (author)

An indirect technique for assuring simplicity and marginal integrity of provisional restorations during full mouth rehabilitation.

Science.gov (United States)

Al Jabbari, Youssef S; Al-Rasheed, Abdulaziz; Smith, Jesse W; Iacopino, Anthony M

2013-01-01

Full mouth rehabilitation with fixed prosthodontics can be a time- and labor-intensive process. The use of provisional restorations allows the treating clinician to determine the functional and esthetic requirements of the definitive prostheses. However, in the case of full mouth rehabilitation, the individual preparation of provisional restorations for multiple teeth may complicate the provisional phase and increase the treatment time. This article describes a method to simplify the indirect fabrication of provisional restorations for full mouth reconstruction. Provisional restorations may be easily achieved by splinting the provisional restorations in sextants, trimming them according to red pencil marks around the prepared margins as guidelines, and fitting them in the laboratory, utilizing a second set of solid casts for the prepared teeth.

Gay Penguins, Sissy Ducklings ... and Beyond? Exploring Gender and Sexuality Diversity through Children's Literature

Science.gov (United States)

DePalma, Renée

2016-01-01

From 2006 to 2008 UK-based primary school teachers in the "No Outsiders" project explored possibilities for addressing sexualities equality in their classrooms. What all teachers had in common was a resource pack that included 27 children's books exploring themes of gender and sexuality diversity either directly or indirectly (i.e. by…

Tipping and Concentration in Markets with Indirect Network Effects

OpenAIRE

Jean-Pierre H. Dubé; Günter J. Hitsch; Pradeep K. Chintagunta

2010-01-01

This paper develops a framework for measuring “tipping”—the increase in a firm's market share dominance caused by indirect network effects. Our measure compares the expected concentration in a market to the hypothetical expected concentration that would arise in the absence of indirect network effects. In practice, this measure requires a model that can predict the counterfactual market concentration under different parameter values capturing the strength of indirect network effects. We build...

The Adoption of Indirect Instruments of Monetary Policy

OpenAIRE

Tomás J. T. Baliño; Charles Enoch; William E. Alexander

1995-01-01

This paper examines the experience of implementing indirect instruments of monetary policy. The experiences of country studies illustrate the variety of circumstances under which indirect instruments of monetary policy have been introduced. Case Studies are presented for Chile, Egypt, Ghana, Indonesia, Mexico, New Zealand, and Poland.

The association between reality-based beliefs and indirectly experienced traumatization.

Science.gov (United States)

Shiri, Shimon; Wexler, Isaiah D; Schwartz, Isabella; Kadari, Michal; Kreitler, Shulamith

2010-12-01

The purpose of the study was to examine the association between belief types and the magnitude of indirect traumatization. Specific types of beliefs were defined in terms of the cognitive orientation theory, which is a cognitive-motivational approach to the understanding, predicting, and changing of behaviors. Belief types that were analyzed included beliefs about self, general beliefs, beliefs about norms, and goal beliefs as they relate to personal growth. Study participants included 38 rescuers (body handlers), 37 nurses, and 31 rehabilitation workers who treated injured civilians that had been exposed to politically motivated violence. The Cognitive Orientation for Posttraumatic Growth Scale was used to assess beliefs about personal growth. The Revised Posttraumatic Stress Disorder Inventory was administered to evaluate indirect traumatization. The results indicate that three of the four belief types related to personal growth were associated with the level of indirect traumatization. Optimistic and positive beliefs about self and general beliefs were associated with a lower level of indirect traumatization symptomatology, suggesting that these types of beliefs may counteract indirect traumatization. On the other hand, stronger goal beliefs were associated with greater indirect traumatization. The negative association between positive goal beliefs and indirect trauma may be related to the gap the individual perceives between the hoped-for ideals and the trauma-stricken reality. These results indicate the importance of cognitive beliefs and their possible role in determining the response to indirect traumatization.

Direct versus indirect detection of supersymmetric dark matter

International Nuclear Information System (INIS)

2003-01-01

This document gathers the slides that were presented during the workshop 'direct versus indirect detection of supersymmetric dark matter'(about 30 contributions). This workshop intended to bring together people from the particle theory community, astrophysicists and cosmologists, as well as experimentalists involved in the detection of dark matter. The aim is to generate a discussion about current and future strategies for detection of SUSY dark matter (with focus, but not exclusively, on neutralinos). Complementarities between accelerator, direct and indirect searches as well as a comparison between the uncertainties in direct and indirect searches of dark matter, are supposed to be discussed. Among the issues which will be addressed are: -) the crucial questions related to the structure of galaxies (local dark matter density, clumping, anomalous velocity distributions, etc.) ; -) the possibilities offered by the present and future experimental facilities for direct and indirect (photon, neutrino) searches; -) the potential for the discovery of SUSY at LHC and beyond; and -) the parameterization of the SUSY breaking models beyond the minimal versions

Theoretical and testing performance of an innovative indirect evaporative chiller

Energy Technology Data Exchange (ETDEWEB)

Jiang, Yi; Xie, Xiaoyun [Department of Building Science and Technology, Tsinghua University, Beijing (China)

2010-12-15

An indirect evaporative chiller is a device used to produce chilled water at a temperature between the wet bulb temperature and dew point of the outdoor air, which can be used in building HVAC systems. This article presents a theoretical analysis and practical performance of an innovative indirect evaporative chiller. First, the process of the indirect evaporative chiller is introduced; then, the matching characteristics of the process are presented and analyzed. It can be shown that the process that produces cold water by using dry air is a nearly-reversible process, so the ideal produced chilled water temperature of the indirect evaporative chiller can be set close to the dew point temperature of the chiller's inlet air. After the indirect evaporative chiller was designed, simulations were done to analyze the output water temperature, the cooling efficiency relative to the inlet dew point temperature, and the COP that the chiller can performance. The first installation of the indirect evaporative chiller of this kind has been run for 5 years in a building in the city of Shihezi. The tested output water temperature of the chiller is around 14-20 C, which is just in between of the outdoor wet bulb temperature and dew point. The tested COP{sub r,s} of the developed indirect evaporative chiller reaches 9.1. Compared with ordinary air conditioning systems, the indirect evaporative chiller can save more than 40% in energy consumption due to the fact that the only energy consumed is from pumps and fans. An added bonus is that the indirect evaporative chiller uses no CFCs that pollute to the aerosphere. The tested internal parameters, such as the water-air flow rate ratio and heat transfer area for each heat transfer process inside the chiller, were analyzed and compared with designed values. The tested indoor air conditions, with a room temperature of 23-27 C and relative humidity of 50-70%, proved that the developed practical indirect evaporative chiller

Marginal adaptation of CAD-CAM onlays: Influence of preparation design and impression technique.

Science.gov (United States)

Lima, Fernanda Ferruzzi; Neto, Constantino Fernandes; Rubo, José H; Santos, Gildo Coelho; Moraes Coelho Santos, Maria Jacinta

2018-03-15

Factors that may affect the marginal adaptation of computer-aided design and computer-aided manufacturing (CAD-CAM) restorations include preparation design, impression technique, and CAD-CAM system. The influence of impression technique and preparation design on CAD-CAM partial coverage restorations has not been fully addressed. The purpose of this in vitro study was to investigate the influence of direct and indirect digital impression techniques and 2 preparation designs on the marginal adaptation of CAD-CAM onlays. Two mesio-occlusal buccal onlay preparations with reduction of the mesiobuccal cusp were made: conventional preparation (CP) with a 1.2-mm modified shoulder margin and modified preparation (MP) flat cuspal reduction without shoulder. Virtual models were generated from each preparation by using a digital scanner (BlueCam; Dentsply Sirona) from the plastic teeth (direct digital impression) or from the stone dies (indirect digital impression). Onlays were designed using a CAD-CAM system (CEREC 4.0; Dentsply Sirona), and nanoceramic resin blocks (Lava Ultimate Restorative; 3M ESPE) were milled using the CEREC MCX milling machine. Marginal discrepancy was evaluated using an optical stereomicroscope at ×25 magnification in 18 locations distributed along the margins of the preparation. The data were analyzed by using 3-way ANOVA followed by the Tukey HSD test (α=.05). CP presented a statistically significant reduced average marginal adaptation (59 ±50 μm) than did MP (69 ±58 μm) (Pmarginal discrepancy in the mesial and buccal locations of MP when compared with CP. Regarding impression techniques, the buccal location presented the smallest average marginal discrepancy in restorations fabricated with indirect impression when compared with direct impression (42 ±33 μm and 60 ±39 μm) (Pmargin presented improved marginal adaptation compared with modified preparation with flat cuspal reduction. Direct and indirect digital impression techniques produced

Rayleigh-wave scattering by shallow cracks using the indirect boundary element method

International Nuclear Information System (INIS)

Ávila-Carrera, R; Rodríguez-Castellanos, A; Ortiz-Alemán, C; Sánchez-Sesma, F J

2009-01-01

The scattering and diffraction of Rayleigh waves by shallow cracks using the indirect boundary element method (IBEM) are investigated. The detection of cracks is of interest because their presence may compromise structural elements, put technological devices at risk or represent economical potential in reservoir engineering. Shallow cracks may give rise to scattered body and surface waves. These waves are sensitive to the crack's geometry, size and orientation. Under certain conditions, amplitude spectra clearly show conspicuous resonances that are associated with trapped waves. Several applications based on the scattering of surface waves (e.g. Rayleigh and Stoneley waves), such as non-destructive testing or oil well exploration, have shown that the scattered fields may provide useful information to detect cracks and other heterogeneities. The subject is not new and several analytical and numerical techniques have been applied for the last 50 years to understand the basis of multiple scattering phenomena. In this work, we use the IBEM to calculate the scattered fields produced by single or multiple cracks near a free surface. This method is based upon an integral representation of the scattered displacement fields, which is derived from Somigliana's identity. Results are given in both frequency and time domains. The analyses of the displacement field using synthetic seismograms and snapshots reveal some important effects from various configurations of cracks. The study of these simple cases may provide an archetype to geoscientists and engineers to understand the fundamental aspects of multiple scattering and diffraction by cracks

Development of a computational technique to measure cartilage contact area.

Science.gov (United States)

Willing, Ryan; Lapner, Michael; Lalone, Emily A; King, Graham J W; Johnson, James A

2014-03-21

Computational measurement of joint contact distributions offers the benefit of non-invasive measurements of joint contact without the use of interpositional sensors or casting materials. This paper describes a technique for indirectly measuring joint contact based on overlapping of articular cartilage computer models derived from CT images and positioned using in vitro motion capture data. The accuracy of this technique when using the physiological nonuniform cartilage thickness distribution, or simplified uniform cartilage thickness distributions, is quantified through comparison with direct measurements of contact area made using a casting technique. The efficacy of using indirect contact measurement techniques for measuring the changes in contact area resulting from hemiarthroplasty at the elbow is also quantified. Using the physiological nonuniform cartilage thickness distribution reliably measured contact area (ICC=0.727), but not better than the assumed bone specific uniform cartilage thicknesses (ICC=0.673). When a contact pattern agreement score (s(agree)) was used to assess the accuracy of cartilage contact measurements made using physiological nonuniform or simplified uniform cartilage thickness distributions in terms of size, shape and location, their accuracies were not significantly different (p>0.05). The results of this study demonstrate that cartilage contact can be measured indirectly based on the overlapping of cartilage contact models. However, the results also suggest that in some situations, inter-bone distance measurement and an assumed cartilage thickness may suffice for predicting joint contact patterns. Copyright © 2014 Elsevier Ltd. All rights reserved.

The Mississippian Leadville Limestone Exploration Play, Utah and Colorado-Exploration Techniques and Studies for Independents

Energy Technology Data Exchange (ETDEWEB)

Thomas Chidsey

2008-09-30

The Mississippian (late Kinderhookian to early Meramecian) Leadville Limestone is a shallow, open-marine, carbonate-shelf deposit. The Leadville has produced over 53 million barrels (8.4 million m{sup 3}) of oil/condensate from seven fields in the Paradox fold and fault belt of the Paradox Basin, Utah and Colorado. The environmentally sensitive, 7500-square-mile (19,400 km{sup 2}) area that makes up the fold and fault belt is relatively unexplored. Only independent producers operate and continue to hunt for Leadville oil targets in the region. The overall goal of this study is to assist these independents by (1) developing and demonstrating techniques and exploration methods never tried on the Leadville Limestone, (2) targeting areas for exploration, (3) increasing deliverability from new and old Leadville fields through detailed reservoir characterization, (4) reducing exploration costs and risk especially in environmentally sensitive areas, and (5) adding new oil discoveries and reserves. The final results will hopefully reduce exploration costs and risks, especially in environmentally sensitive areas, and add new oil discoveries and reserves. The study consists of three sections: (1) description of lithofacies and diagenetic history of the Leadville at Lisbon field, San Juan County, Utah, (2) methodology and results of a surface geochemical survey conducted over the Lisbon and Lightning Draw Southeast fields (and areas in between) and identification of oil-prone areas using epifluorescence in well cuttings from regional wells, and (3) determination of regional lithofacies, description of modern and outcrop depositional analogs, and estimation of potential oil migration directions (evaluating the middle Paleozoic hydrodynamic pressure regime and water chemistry). Leadville lithofacies at Libon field include open marine (crinoidal banks or shoals and Waulsortian-type buildups), oolitic and peloid shoals, and middle shelf. Rock units with open-marine and restricted

The Mississippian Leadville Limestone Exploration Play, Utah and Colorado-Exploration Techniques and Studies for Independents

International Nuclear Information System (INIS)

Thomas Chidsey

2008-01-01

The Mississippian (late Kinderhookian to early Meramecian) Leadville Limestone is a shallow, open-marine, carbonate-shelf deposit. The Leadville has produced over 53 million barrels (8.4 million m 3 ) of oil/condensate from seven fields in the Paradox fold and fault belt of the Paradox Basin, Utah and Colorado. The environmentally sensitive, 7500-square-mile (19,400 km 2 ) area that makes up the fold and fault belt is relatively unexplored. Only independent producers operate and continue to hunt for Leadville oil targets in the region. The overall goal of this study is to assist these independents by (1) developing and demonstrating techniques and exploration methods never tried on the Leadville Limestone, (2) targeting areas for exploration, (3) increasing deliverability from new and old Leadville fields through detailed reservoir characterization, (4) reducing exploration costs and risk especially in environmentally sensitive areas, and (5) adding new oil discoveries and reserves. The final results will hopefully reduce exploration costs and risks, especially in environmentally sensitive areas, and add new oil discoveries and reserves. The study consists of three sections: (1) description of lithofacies and diagenetic history of the Leadville at Lisbon field, San Juan County, Utah, (2) methodology and results of a surface geochemical survey conducted over the Lisbon and Lightning Draw Southeast fields (and areas in between) and identification of oil-prone areas using epifluorescence in well cuttings from regional wells, and (3) determination of regional lithofacies, description of modern and outcrop depositional analogs, and estimation of potential oil migration directions (evaluating the middle Paleozoic hydrodynamic pressure regime and water chemistry). Leadville lithofacies at Libon field include open marine (crinoidal banks or shoals and Waulsortian-type buildups), oolitic and peloid shoals, and middle shelf. Rock units with open-marine and restricted

System markets: Indirect network effects in action, or inaction?

OpenAIRE

Binken, Jeroen

2010-01-01

textabstractIn this dissertation, I empirically examine system markets up close. More specifically I examine indirect network effects, both demand-side and supply-side indirect network effects. Indirect network effects are the source of positive feedback in system markets, or so network effect theory tells us. Systems are composed of complementary and interdependent products, such as hardware and software. For instance, a video game system is composed of the video game console, on the one han...

Indirect detection methods: Looking for what is not there

International Nuclear Information System (INIS)

Yeung, E.S.

1989-01-01

Indirect detection allows one to monitor species that normally do not give a response. It has grown from an intellectual curiosity to become an extremely useful tool. For volume displacement, polarimetry gives the best results. For charge displacement, ion chromatography and capillary zone electrophoresis are ideal situations for applying indirect fluorescence detection. LOD surpasses all but the most specialized detection schemes. Future developments in systems specially designed for indirect detection should make these schemes even more powerful

CONTRIBUTION OF INDIRECT TAXES

Directory of Open Access Journals (Sweden)

CHIRCULESCU MARIA FELICIA

2015-08-01

Full Text Available The work is based on the fact that at any time and in any society, taxation is regarded as undesirable for all taxpayers. The existence and it's manifestation is justified, because the operation of any company involves costs that must be covered by sufficient resources. Since ancient times, each state has adopted its own tax system, more or less perfected, as the state has experienced a greater or lesser economic and military power At the base of this work stays the fact that tax systems are a key factor influencing the overall efficiency of the economy. They determine the size tendency to save, invest and work, influencing the increase in production and employment, which is essential sights integral economic strategy, making tax reform an important component of economic reform. This paper aims to analyze the indirect taxes and their contribution to the public revenues in Romania, the purpose paper contains an analysis based on statistical series as indirect taxation is where tax harmonization was possible. Through analyzes, the paper aims to provide answers to the problem of the contradiction between the growing need for budgetary revenues, which entails a continuous amplification and diversification of taxation, on the one hand, and the need to stimulate economic development, on the other hand. The harmonization of indirect taxation had been achieved since this touches the free movement of goods and the freedom to supply services, not being able to say the same thing about direct taxation, which is why the European Community Treaty does not specify expressly the alignment of direct taxation, considering that direct taxation is a matter of Internal Policies that, for a country free option.

Two facets of stress and indirect effects on child diet through emotion-driven eating.

Science.gov (United States)

Tate, Eleanor B; Spruijt-Metz, Donna; Pickering, Trevor A; Pentz, Mary Ann

2015-08-01

Stress has been associated with high-calorie, low-nutrient food intake (HCLN) and emotion-driven eating (EDE). However, effects on healthy food intake remain unknown. This study examined two facets of stress (self-efficacy, perceived helplessness) and food consumption, mediated by EDE. Cross-sectional data from fourth-graders (n=978; 52% female, 28% Hispanic) in an obesity intervention used self-report to assess self-efficacy, helplessness, EDE, fruit/vegetable (FV) intake, and high-calorie/low-nutrient (HCLN) food. Higher stress self-efficacy was associated with higher FV intake, β=.354, pstress perceived helplessness had an indirect effect on HCLN intake through emotion-driven eating, indirect effect=.094, pStress self-efficacy may be more important for healthy food intake and perceived helplessness may indicate emotion-driven eating and unhealthy snack food intake. Obesity prevention programs may consider teaching stress management techniques to avoid emotion-driven eating. Copyright © 2015 Elsevier Ltd. All rights reserved.

Indirect taxes on food in Southern Brazil

Directory of Open Access Journals (Sweden)

Denize Mirian da Silva

2013-12-01

Full Text Available The objective of this paper is to estimate the indirect tax burden on food for ten income classes, based on income and household total expenditure in southern Brazil. Thus it can be seen as indirect taxes on foods affect the monetary income and consumption pattern of households. To reach the objectives proposed, will be used the Pintos-Payeras (2008 model. The database iscomposed by microdata from the Household Budgeting Survey (POF 2008-2009 and the tax regulations of the country and the southern states of Brazil. The results show that indirect taxes on food in Southern Brazil is regressive when based on income and expenditure of household , ie , the poorest people pay proportionately more taxes and have their consumption pattern highest taxed ICMS (Brazilian value added tax is the tax that contributes most to the regressivity.

Indirect adaptive soft computing based wavelet-embedded control paradigms for WT/PV/SOFC in a grid/charging station connected hybrid power system.

Directory of Open Access Journals (Sweden)

Sidra Mumtaz

Full Text Available This paper focuses on the indirect adaptive tracking control of renewable energy sources in a grid-connected hybrid power system. The renewable energy systems have low efficiency and intermittent nature due to unpredictable meteorological conditions. The domestic load and the conventional charging stations behave in an uncertain manner. To operate the renewable energy sources efficiently for harvesting maximum power, instantaneous nonlinear dynamics should be captured online. A Chebyshev-wavelet embedded NeuroFuzzy indirect adaptive MPPT (maximum power point tracking control paradigm is proposed for variable speed wind turbine-permanent synchronous generator (VSWT-PMSG. A Hermite-wavelet incorporated NeuroFuzzy indirect adaptive MPPT control strategy for photovoltaic (PV system to extract maximum power and indirect adaptive tracking control scheme for Solid Oxide Fuel Cell (SOFC is developed. A comprehensive simulation test-bed for a grid-connected hybrid power system is developed in Matlab/Simulink. The robustness of the suggested indirect adaptive control paradigms are evaluated through simulation results in a grid-connected hybrid power system test-bed by comparison with conventional and intelligent control techniques. The simulation results validate the effectiveness of the proposed control paradigms.

Indirect adaptive soft computing based wavelet-embedded control paradigms for WT/PV/SOFC in a grid/charging station connected hybrid power system.

Science.gov (United States)

Mumtaz, Sidra; Khan, Laiq; Ahmed, Saghir; Bader, Rabiah

2017-01-01

This paper focuses on the indirect adaptive tracking control of renewable energy sources in a grid-connected hybrid power system. The renewable energy systems have low efficiency and intermittent nature due to unpredictable meteorological conditions. The domestic load and the conventional charging stations behave in an uncertain manner. To operate the renewable energy sources efficiently for harvesting maximum power, instantaneous nonlinear dynamics should be captured online. A Chebyshev-wavelet embedded NeuroFuzzy indirect adaptive MPPT (maximum power point tracking) control paradigm is proposed for variable speed wind turbine-permanent synchronous generator (VSWT-PMSG). A Hermite-wavelet incorporated NeuroFuzzy indirect adaptive MPPT control strategy for photovoltaic (PV) system to extract maximum power and indirect adaptive tracking control scheme for Solid Oxide Fuel Cell (SOFC) is developed. A comprehensive simulation test-bed for a grid-connected hybrid power system is developed in Matlab/Simulink. The robustness of the suggested indirect adaptive control paradigms are evaluated through simulation results in a grid-connected hybrid power system test-bed by comparison with conventional and intelligent control techniques. The simulation results validate the effectiveness of the proposed control paradigms.

Indirect adaptive soft computing based wavelet-embedded control paradigms for WT/PV/SOFC in a grid/charging station connected hybrid power system

Science.gov (United States)

Khan, Laiq; Ahmed, Saghir; Bader, Rabiah

2017-01-01

This paper focuses on the indirect adaptive tracking control of renewable energy sources in a grid-connected hybrid power system. The renewable energy systems have low efficiency and intermittent nature due to unpredictable meteorological conditions. The domestic load and the conventional charging stations behave in an uncertain manner. To operate the renewable energy sources efficiently for harvesting maximum power, instantaneous nonlinear dynamics should be captured online. A Chebyshev-wavelet embedded NeuroFuzzy indirect adaptive MPPT (maximum power point tracking) control paradigm is proposed for variable speed wind turbine-permanent synchronous generator (VSWT-PMSG). A Hermite-wavelet incorporated NeuroFuzzy indirect adaptive MPPT control strategy for photovoltaic (PV) system to extract maximum power and indirect adaptive tracking control scheme for Solid Oxide Fuel Cell (SOFC) is developed. A comprehensive simulation test-bed for a grid-connected hybrid power system is developed in Matlab/Simulink. The robustness of the suggested indirect adaptive control paradigms are evaluated through simulation results in a grid-connected hybrid power system test-bed by comparison with conventional and intelligent control techniques. The simulation results validate the effectiveness of the proposed control paradigms. PMID:28877191

Nr 1115 National Assembly, Nr 640 Senate - Stage report on alternate techniques to hydraulic fracturing for the exploration and exploitation of non conventional hydrocarbons

International Nuclear Information System (INIS)

Lenoir, Jean-Claude; Bataille, Christian

2013-01-01

While noticing that these resources are more supposed that demonstrated, this report first addresses the potential of non conventional hydrocarbon resources: definition, forms and assessment. It presents the status and locations of such resources in France, and discusses how uncertainties can be reduced as far as gas shale and hydrocarbons are concerned (exploration drillings seem necessary). The second part proposes an overview of the various extraction techniques: technologies without fracturing, and hydraulic fracturing (description, recall of previous uses in France, technique management). The third part presents alternate techniques as research topics to be explored: stimulation by another pressurized fluid than water, or by other physical processes (electric arc, thermal process). Proposals are stated. The document also comprised a report of meeting of the scientific committee, a list of heard persons, and a feasibility study

Legal Realism in Action: Indirect Copyright Liability's Continuing Tort Framework and Sony’s de facto Demise

OpenAIRE

Menell, Peter S.; Nimmer, David

2007-01-01

The Supreme Court’s indirect copyright liability standard, derived in Sony Corporation of America v. Universal City Studios from patent law and reasserted in Metro-Goldwyn-Mayer Studios Inc. v. Grokster, Ltd, is widely seen as creating a safe harbor for distributors of dual use technologies. Yet, when one looks to cases decided since Sony, legislative enactments, and the decisions of technology companies in the marketplace, a very different reality emerges. This article explores and explains ...

Indirect reduction with a condylar blade plate for osteosynthesis of subtrochanteric femoral fractures.

Science.gov (United States)

Siebenrock, K A; Müller, U; Ganz, R

1998-01-01

Subtrochanteric fractures frequently occur as high energy trauma usually in younger patients and may lead to severe comminution of the medial cortex. The medial cortex of the proximal femur is exposed to high compressive forces which make fracture stabilization a difficult problem. Bone healing may be seriously compromised due to extensive comminution and fragment devitalization. This requires reduction techniques which do not cause additional damage to the vitality of the bone. With indirect reduction techniques and the use of a condylar blade plate the results have been significantly improved in these fracture types in our department (1). In this report the essential aspects of indirect reduction for subtrochanteric fractures using a condylar blade plate and the treatment results from our department from earlier years (1) and from the last 2 1/2 years will be presented. In the latter period, fifteen patients with a mean age of 49 years (19-87 years) were treated with this method. Fractures resulted from traffic incidents or falls from a great height in 11 cases (73%). Union was achieved in 14 cases (93%) with full weight-bearing after a mean of 3 months (1-4 1/2 months). Malunion was seen in two cases (13%) without the need for further surgery. Non union occurred in one patient (7%) with a III B open injury due to early infection. After repeated debridements, bone grafting and decortication, the fracture was stabilized with a replacement condylar blade plate and healed uneventfully.

Assessing Natural Direct and Indirect Effects Through Multiple Pathways

DEFF Research Database (Denmark)

Lange, T; Rasmussen, M; Thygesen, Lau Caspar

2014-01-01

. The approach is an extension of the natural effect models proposed by Lange et al. (Am J Epidemiol. 2012;176(3):190-195). By allowing the analysis of distinct multiple pathways, the suggested approach adds to the capabilities of modern mediation techniques. Furthermore, the approach can be implemented using......Within the fields of epidemiology, interventions research and social sciences researchers are often faced with the challenge of decomposing the effect of an exposure into different causal pathways working through defined mediator variables. The goal of such analyses is often to understand...... the mechanisms of the system or to suggest possible interventions. The case of a single mediator, thus implying only 2 causal pathways (direct and indirect) from exposure to outcome, has been extensively studied. By using the framework of counterfactual variables, researchers have established theoretical...

A Green's Function Approach to Simulate DNA Damage by the Indirect Effect

Science.gov (United States)

Plante, Ianik; Cicinotta, Francis A.

2013-01-01

The DNA damage is of fundamental importance in the understanding of the effects of ionizing radiation. DNA is damaged by the direct effect of radiation (e.g. direct ionization) and by indirect effect (e.g. damage by.OH radicals created by the radiolysis of water). Despite years of research, many questions on the DNA damage by ionizing radiation remains. In the recent years, the Green's functions of the diffusion equation (GFDE) have been used extensively in biochemistry [1], notably to simulate biochemical networks in time and space [2]. In our future work on DNA damage, we wish to use an approach based on the GFDE to refine existing models on the indirect effect of ionizing radiation on DNA. To do so, we will use the code RITRACKS [3] developed at the NASA Johnson Space Center to simulate the radiation track structure and calculate the position of radiolytic species after irradiation. We have also recently developed an efficient Monte-Carlo sampling algorithm for the GFDE of reversible reactions with an intermediate state [4], which can be modified and adapted to simulate DNA damage by free radicals. To do so, we will use the known reaction rate constants between radicals (OH, eaq, H,...) and the DNA bases, sugars and phosphates and use the sampling algorithms to simulate the diffusion of free radicals and chemical reactions with DNA. These techniques should help the understanding of the contribution of the indirect effect in the formation of DNA damage and double-strand breaks.

The direct and indirect costs of managing chronic obstructive pulmonary disease in Greece.

Science.gov (United States)

Souliotis, Kyriakos; Kousoulakou, Hara; Hillas, Georgios; Tzanakis, Nikos; Toumbis, Michalis; Vassilakopoulos, Theodoros

2017-01-01

COPD is associated with significant economic burden. The objective of this study was to explore the direct and indirect costs associated with COPD and identify the key cost drivers of disease management in Greece. A Delphi panel of Greek pulmonologists was conducted, which aimed at eliciting local COPD treatment patterns and resource use. Resource use was translated into costs using official health insurance tariffs and Diagnosis-Related Groups (DRGs). In addition, absenteeism and caregiver's costs were recorded in order to quantify indirect COPD costs. The total costs of managing COPD per patient per year were estimated at €4,730, with direct (medical and nonmedical) and indirect costs accounting for 62.5% and 37.5%, respectively. COPD exacerbations were responsible for 32% of total costs (€1,512). Key exacerbation-related cost drivers were hospitalization (€830) and intensive care unit (ICU) admission costs (€454), jointly accounting for 85% of total exacerbation costs. Annual maintenance phase costs were estimated at €835, with pharmaceutical treatment accounting for 77% (€639.9). Patient time costs were estimated at €146 per year. The average number of sick days per year was estimated at 16.9, resulting in productivity losses of €968. Caregiver's costs were estimated at €806 per year. The management of COPD in Greece is associated with intensive resource use and significant economic burden. Exacerbations and productivity losses are the key cost drivers. Cost containment policies should focus on prioritizing treatments that increase patient compliance as these can lead to reduction of exacerbations, longer maintenance phases, and thus lower costs.

Properties of hypothesis testing techniques and (Bayesian) model selection for exploration-based and theory-based (order-restricted) hypotheses.

Science.gov (United States)

Kuiper, Rebecca M; Nederhoff, Tim; Klugkist, Irene

2015-05-01

In this paper, the performance of six types of techniques for comparisons of means is examined. These six emerge from the distinction between the method employed (hypothesis testing, model selection using information criteria, or Bayesian model selection) and the set of hypotheses that is investigated (a classical, exploration-based set of hypotheses containing equality constraints on the means, or a theory-based limited set of hypotheses with equality and/or order restrictions). A simulation study is conducted to examine the performance of these techniques. We demonstrate that, if one has specific, a priori specified hypotheses, confirmation (i.e., investigating theory-based hypotheses) has advantages over exploration (i.e., examining all possible equality-constrained hypotheses). Furthermore, examining reasonable order-restricted hypotheses has more power to detect the true effect/non-null hypothesis than evaluating only equality restrictions. Additionally, when investigating more than one theory-based hypothesis, model selection is preferred over hypothesis testing. Because of the first two results, we further examine the techniques that are able to evaluate order restrictions in a confirmatory fashion by examining their performance when the homogeneity of variance assumption is violated. Results show that the techniques are robust to heterogeneity when the sample sizes are equal. When the sample sizes are unequal, the performance is affected by heterogeneity. The size and direction of the deviations from the baseline, where there is no heterogeneity, depend on the effect size (of the means) and on the trend in the group variances with respect to the ordering of the group sizes. Importantly, the deviations are less pronounced when the group variances and sizes exhibit the same trend (e.g., are both increasing with group number). © 2014 The British Psychological Society.

Indirect Estimation of Selected Measures of Fertility and Marital ...

African Journals Online (AJOL)

DLHS6

2018-01-09

Jan 9, 2018 ... marital status distribution data of India especially of the 2011 census in deriving indirectly the fertility measures .... 2011 Census, Economic and Political weekly, EPW Vol. ... Indirect Estimates of Total Fertility Rate Using Child.

Direct versus indirect detection of supersymmetric dark matter

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-07-01

This document gathers the slides that were presented during the workshop 'direct versus indirect detection of supersymmetric dark matter'(about 30 contributions). This workshop intended to bring together people from the particle theory community, astrophysicists and cosmologists, as well as experimentalists involved in the detection of dark matter. The aim is to generate a discussion about current and future strategies for detection of SUSY dark matter (with focus, but not exclusively, on neutralinos). Complementarities between accelerator, direct and indirect searches as well as a comparison between the uncertainties in direct and indirect searches of dark matter, are supposed to be discussed. Among the issues which will be addressed are: -) the crucial questions related to the structure of galaxies (local dark matter density, clumping, anomalous velocity distributions, etc.) ; -) the possibilities offered by the present and future experimental facilities for direct and indirect (photon, neutrino) searches; -) the potential for the discovery of SUSY at LHC and beyond; and -) the parameterization of the SUSY breaking models beyond the minimal versions.

Exploring JLA supernova data with improved flux-averaging technique

Energy Technology Data Exchange (ETDEWEB)

Wang, Shuang; Wen, Sixiang; Li, Miao, E-mail: wangshuang@mail.sysu.edu.cn, E-mail: wensx@mail2.sysu.edu.cn, E-mail: limiao9@mail.sysu.edu.cn [School of Physics and Astronomy, Sun Yat-Sen University, University Road (No. 2), Zhuhai (China)

2017-03-01

In this work, we explore the cosmological consequences of the ''Joint Light-curve Analysis'' (JLA) supernova (SN) data by using an improved flux-averaging (FA) technique, in which only the type Ia supernovae (SNe Ia) at high redshift are flux-averaged. Adopting the criterion of figure of Merit (FoM) and considering six dark energy (DE) parameterizations, we search the best FA recipe that gives the tightest DE constraints in the ( z {sub cut}, Δ z ) plane, where z {sub cut} and Δ z are redshift cut-off and redshift interval of FA, respectively. Then, based on the best FA recipe obtained, we discuss the impacts of varying z {sub cut} and varying Δ z , revisit the evolution of SN color luminosity parameter β, and study the effects of adopting different FA recipe on parameter estimation. We find that: (1) The best FA recipe is ( z {sub cut} = 0.6, Δ z =0.06), which is insensitive to a specific DE parameterization. (2) Flux-averaging JLA samples at z {sub cut} ≥ 0.4 will yield tighter DE constraints than the case without using FA. (3) Using FA can significantly reduce the redshift-evolution of β. (4) The best FA recipe favors a larger fractional matter density Ω {sub m} . In summary, we present an alternative method of dealing with JLA data, which can reduce the systematic uncertainties of SNe Ia and give the tighter DE constraints at the same time. Our method will be useful in the use of SNe Ia data for precision cosmology.

Estimating direct and indirect costs of premenstrual syndrome.

Science.gov (United States)

Borenstein, Jeff; Chiou, Chiun-Fang; Dean, Bonnie; Wong, John; Wade, Sally

2005-01-01

To quantify the economic impact of premenstrual syndrome (PMS) on the employer. Data were collected from 374 women aged 18-45 with regular menses. Direct costs were quantified using administrative claims of these patients and the Medicare Fee Schedule. Indirect costs were quantified by both self-reported days of work missed and lost productivity at work. Regression analyses were used to develop a model to project PMS-related direct and indirect costs. A total of 29.6% (n = 111) of the participants were diagnosed with PMS. A PMS diagnosis was associated with an average annual increase of $59 in direct costs (P increase in direct medical costs and a large increase in indirect costs.

Exploring a Nearby Habitable World...Orbiting an M-Dwarf Star

Science.gov (United States)

Deming, Drake

2010-01-01

Topics include: the landscape of extrasolar planets and detection techniques, direct and indirect detection methods, summary of the known exoplanets, exploiting transits to characterize super earth atmospheres, how to characterize exoplanet atmospheres, and emitted or reflected spectra of hot Jupiters.

Evaluation of marginal and internal gaps of metal ceramic crowns obtained from conventional impressions and casting techniques with those obtained from digital techniques.

Science.gov (United States)

Rai, Rathika; Kumar, S Arun; Prabhu, R; Govindan, Ranjani Thillai; Tanveer, Faiz Mohamed

2017-01-01

Accuracy in fit of cast metal restoration has always remained as one of the primary factors in determining the success of the restoration. A well-fitting restoration needs to be accurate both along its margin and with regard to its internal surface. The aim of the study is to evaluate the marginal fit of metal ceramic crowns obtained by conventional inlay casting wax pattern using conventional impression with the metal ceramic crowns obtained by computer-aided design and computer-aided manufacturing (CAD/CAM) technique using direct and indirect optical scanning. This in vitro study on preformed custom-made stainless steel models with former assembly that resembles prepared tooth surfaces of standardized dimensions comprised three groups: the first group included ten samples of metal ceramic crowns fabricated with conventional technique, the second group included CAD/CAM-milled direct metal laser sintering (DMLS) crowns using indirect scanning, and the third group included DMLS crowns fabricated by direct scanning of the stainless steel model. The vertical marginal gap and the internal gap were evaluated with the stereomicroscope (Zoomstar 4); post hoc Turkey's test was used for statistical analysis. One-way analysis of variance method was used to compare the mean values. Metal ceramic crowns obtained from direct optical scanning showed the least marginal and internal gap when compared to the castings obtained from inlay casting wax and indirect optical scanning. Indirect and direct optical scanning had yielded results within clinically acceptable range.

Circumventing resistance: using values to indirectly change attitudes.

Science.gov (United States)

Blankenship, Kevin L; Wegener, Duane T; Murray, Renee A

2012-10-01

Most research on persuasion examines messages that directly address the attitude of interest. However, especially when message recipients are inclined to resist change, indirect methods might be more effective. Because values are rarely attacked and defended, value change could serve as a useful indirect route for attitude change. Attitudes toward affirmative action changed more when the value of equality was attacked (indirect change) than when affirmative action was directly attacked using the same message (Experiments 1-2). Changes in confidence in the value were responsible for the indirect change when the value was attacked (controlling for changes in favorability toward the value), whereas direct counterarguments to the message were responsible for the relative lack of change when the attitude was attacked directly (Experiment 2). Attacking the value of equality influenced attitudes toward policies related to the value but left policy attitudes unrelated to the value unchanged (Experiment 3). Finally, a manipulation of value confidence that left attitudes toward the value intact demonstrated similar confidence-based influences on policies related to the value of freedom (Experiment 4). Undermined value confidence also resulted in less confidence in the resulting policy attitudes controlling for the changes in the policy attitudes themselves (Experiments 3 and 4). Therefore, indirect change through value attacks presented a double threat--to both the policy attitudes and the confidence with which those policy attitudes were held (potentially leaving them open to additional influence).

PREFACE: Exploring surfaces and buried interfaces of functional materials by advanced x-ray and neutron techniques Exploring surfaces and buried interfaces of functional materials by advanced x-ray and neutron techniques

Science.gov (United States)

Sakurai, Kenji

2010-12-01

This special issue is devoted to describing recent applications of x-ray and neutron scattering techniques to the exploration of surfaces and buried interfaces of various functional materials. Unlike many other surface-sensitive methods, these techniques do not require ultra high vacuum, and therefore, a variety of real and complicated surfaces fall within the scope of analysis. It must be particularly emphasized that the techniques are capable of seeing even buried function interfaces as well as the surface. Furthermore, the information, which ranges from the atomic to mesoscopic scale, is highly quantitative and reproducible. The non-destructive nature of the techniques is another important advantage of using x-rays and neutrons, when compared with other atomic-scale analyses. This ensures that the same specimen can be measured by other techniques. Such features are fairly attractive when exploring multilayered materials with nanostructures (dots, tubes, wires, etc), which are finding applications in electronic, magnetic, optical and other devices. The Japan Applied Physics Society has established a group to develop the research field of studying buried function interfaces with x-rays and neutrons. As the methods can be applied to almost all types of materials, from semiconductor and electronic devices to soft materials, participants have fairly different backgrounds but share a common interest in state-of-the-art x-ray and neutron techniques and sophisticated applications. A series of workshops has been organized almost every year since 2001. Some international interactions have been continued intensively, although the community is part of a Japanese society. This special issue does not report the proceedings of the recent workshop, although all the authors are in some way involved in the activities of the above society. Initially, we intended to collect quite long overview papers, including the authors' latest and most important original results, as well as

Heterogeneity of relationally aggressive adolescents in Taiwan: direct and indirect relational aggression.

Science.gov (United States)

Cheng, Ching-Ling

2014-11-01

Relational aggressors mistreat their targets in covert ways; however, they also inflict psychological harm to victims. A clarification of the distinctive function of the perpetrators' destructive patterns would be helpful for interventional consideration. This study's purpose was to, first, explore the classification of relational aggression (RA) by means of operational channels, and then, to examine the psychosocial characteristics of each subtype. The participants were 860 junior high school students (431 boys, M age = 14.2) from four schools in Taiwan. Self-reported measures of empathy, normative beliefs of RA, and coping strategy of interpersonal conflicts were used for data collection, as well as peer-nominated measures of RA and peer acceptance. By means of cluster analyses, five clusters were identified: direct, indirect, severe/combined, mild/combined, and uninvolved. The meaningfulness of the resultant cluster solution was examined through the analysis of social-cognitive, affective, and behavioral features as well as psychosocial adjustment. The findings indicated that different subgroups of relational aggressors demonstrated distinct psychosocial characteristics. In particular, in contrast to non-involved adolescents, the direct group tended to regard RA as acceptable, and the indirect group was more likely to rely on social support and have negative emotional reactions in dealing with interpersonal problems. © The Author(s) 2014.

Exploring Graduate Students' Perspectives towards Using Gamification Techniques in Online Learning

Directory of Open Access Journals (Sweden)

Daniah ALABBASI

2017-07-01

Full Text Available Teachers and educational institutions are attempting to find an appropriate strategy to motivate as well as engage students in the learning process. Institutions are encouraging the use of gamification in education for the purpose of improving the intrinsic motivation as well as engagement. However, the students’ perspective of the issue is under-investigated. The purpose of this research study was to explore graduate students’ perspectives toward the use of gamification techniques in online learning. The study used exploratory research and survey as the data collection tool. Forty-seven graduate students (n = 47 enrolled in an instructional technology program studied in a learning management system that supports gamification (TalentLMS. The average total percentages were calculated for each survey section to compose the final perspective of the included students. The results showed a positive perception toward the use of gamification tools in online learning among graduate students. Students require effort-demanding, challenging, sophisticated learning systems that increase competency, enhance recall memory, concentration, attentiveness, commitment, and social interaction. Limitations of the study are identified, which highlights the need for further research on the subject matter.

Global indirect aerosol effects: a review

Directory of Open Access Journals (Sweden)

U. Lohmann

2005-01-01

Full Text Available Aerosols affect the climate system by changing cloud characteristics in many ways. They act as cloud condensation and ice nuclei, they may inhibit freezing and they could have an influence on the hydrological cycle. While the cloud albedo enhancement (Twomey effect of warm clouds received most attention so far and traditionally is the only indirect aerosol forcing considered in transient climate simulations, here we discuss the multitude of effects. Different approaches how the climatic implications of these aerosol effects can be estimated globally as well as improvements that are needed in global climate models in order to better represent indirect aerosol effects are discussed in this paper.

Surface exploration geophysics applied to the moon

International Nuclear Information System (INIS)

Ander, M.E.

1984-01-01

With the advent of a permanent lunar base, the desire to explore the lunar near-surface for both scientific and economic purposes will arise. Applications of exploration geophysical methods to the earth's subsurface are highly developed. This paper briefly addresses some aspects of applying this technology to near surface lunar exploration. It is noted that both the manner of application of some techniques, as well as their traditional hierarchy as assigned on earth, should be altered for lunar exploration. In particular, electromagnetic techniques may replace seismic techniques as the primary tool for evaluating near-surface structure

Serological response to an indirect and a competitive elisa in heifers vaccinated with Brucella abortus strain 19

International Nuclear Information System (INIS)

Carrasco, E.A.; Uzal, F.A.; Echaide, S.

1998-01-01

The different serologic techniques for bovine brucellosis diagnosis have different abilities to detect antibodies after vaccination with Brucella abortus strain 19. The humoral response in heifers vaccinated with Brucella abortus strain 19 was evaluated by using several serologic techniques. In the experimental field of INTA, Pilcaniyeu, Rio Negro province, sixteen 5 months old heifers were vaccinated subcutaneously with a standard dose (2ml, containing 20x10 9 to 10x10 9 living organisms) of Brucella abortus strain 19. Sera from all the heifers were obtained on 18 occasions (one 87 days before vaccination, one immediately before vaccination and on 16 occasions after vaccination, during 488 days) and analyzed by buffered plate antigen test, rose bengal test, standard tube agglutination test, 2-mercaptoetanol test, complement fixation test, indirect ELISA, and competitive ELISA. Prior vaccination, 100% of the heifers gave negative results in all the techniques used, while 100% of them gave positive reaction in the first sampling after vaccination to all the techniques, with the exception of standard tube agglutination test that showed agglutinating titters of 1/100 or higher (positive threshold) in only 71.4% of the heifers. The indirect ELISA technique showed a reducing percentage of positive animals up until 316 days after vaccination, after which positive results were obtained. The competitive ELISA gave positive results in a variable number of heifers up to 253 days after vaccination when 100% of the sera were negative to this technique. Buffered plate antigen test was the technique that gave positive results for a longest period, being 100% of the animals negative to this technique at 450 days after vaccination. The other serological techniques assayed gave positive results during variable periods of time, intermediate between standard tube agglutination test and buffered plate antigen test. Although the present results were obtained from a limited number of

Separating Direct and Indirect Turbofan Engine Combustion Noise While Estimating Post-Combustion (Post-Flame) Residence Time Using the Correlation Function

Science.gov (United States)

Miles, Jeffrey Hilton

2011-01-01

A previous investigation on the presence of direct and indirect combustion noise for a full-scale turbofan engine using a far-field microphone at 130 is extended by also examining signals obtained at two additional downstream directions using far-field microphones at 110 deg and 160 deg. A generalized cross-correlation function technique is used to study the change in propagation time to the far field of the combined direct and indirect combustion noise signal as a sequence of low-pass filters are applied. The filtering procedure used produces no phase distortion. As the low-pass filter frequency is decreased, the travel time increases because the relative amount of direct combustion noise is reduced. The indirect combustion noise signal travels more slowly because in the combustor entropy fluctuations move with the flow velocity, which is slow compared to the local speed of sound. The indirect combustion noise signal travels at acoustic velocities after reaching the turbine and being converted into an acoustic signal. The direct combustion noise is always propagating at acoustic velocities. The results show that the estimated indirect combustion noise time delay values (post-combustion residence times) measured at each angle are fairly consistent with one another for a relevant range of operating conditions and demonstrate source separation of a mixture of direct and indirect combustion noise. The results may lead to a better idea about the acoustics in the combustor and may help develop and validate improved reduced-order physics-based methods for predicting turbofan engine core noise.

Indirect Catastrophic Injuries in Olympic Styles of Wrestling in Iran

OpenAIRE

Kordi, Ramin; Ziaee, Vahid; Rostami, Mohsen; Wallace, W. Angus

2011-01-01

Background: Data on indirect catastrophic injuries in wrestling are scarce. Objectives: To develop a profile of indirect catastrophic injuries in international styles of wrestling and to describe possible risk factors. Study Design: Retrospective case series; Level of evidence, 3. Methods: Indirect catastrophic injuries that occurred in wrestling clubs in Iran from July 1998 to June 2005 were identified by contacting several sources. The cases were retrospectively reviewed. Results: The injur...

Inconsistency between direct and indirect comparisons of competing interventions: meta-epidemiological study.

Science.gov (United States)

Song, Fujian; Xiong, Tengbin; Parekh-Bhurke, Sheetal; Loke, Yoon K; Sutton, Alex J; Eastwood, Alison J; Holland, Richard; Chen, Yen-Fu; Glenny, Anne-Marie; Deeks, Jonathan J; Altman, Doug G

2011-08-16

To investigate the agreement between direct and indirect comparisons of competing healthcare interventions. Meta-epidemiological study based on sample of meta-analyses of randomised controlled trials. Data sources Cochrane Database of Systematic Reviews and PubMed. Inclusion criteria Systematic reviews that provided sufficient data for both direct comparison and independent indirect comparisons of two interventions on the basis of a common comparator and in which the odds ratio could be used as the outcome statistic. Inconsistency measured by the difference in the log odds ratio between the direct and indirect methods. The study included 112 independent trial networks (including 1552 trials with 478,775 patients in total) that allowed both direct and indirect comparison of two interventions. Indirect comparison had already been explicitly done in only 13 of the 85 Cochrane reviews included. The inconsistency between the direct and indirect comparison was statistically significant in 16 cases (14%, 95% confidence interval 9% to 22%). The statistically significant inconsistency was associated with fewer trials, subjectively assessed outcomes, and statistically significant effects of treatment in either direct or indirect comparisons. Owing to considerable inconsistency, many (14/39) of the statistically significant effects by direct comparison became non-significant when the direct and indirect estimates were combined. Significant inconsistency between direct and indirect comparisons may be more prevalent than previously observed. Direct and indirect estimates should be combined in mixed treatment comparisons only after adequate assessment of the consistency of the evidence.

Trojan Horse Method: A tool to explore electron screening effect

Energy Technology Data Exchange (ETDEWEB)

Pizzone, R G; Spitaleri, C; Cherubini, S; Cognata, M La; Lamia, L; Romano, S; Sergi, M L [Laboratori Nazionali del Sud-INFN, Catania (Italy) and Dipartimento di Metodologie Fisiche e Chimiche per l' Ingegneria, Universita di Catania, Catania (Italy); Rolfs, C; Strieder, F [Ruhr Universitaet Bochum (Germany); Burjan, V; Kroha, V; Mrazek, J [Cyclotron Institute, Academy of Science, Rez (Czech Republic); Li, C; Wen, Q; Zhou, S [CIAE, Beijing (China); Tumino, A, E-mail: rgpizzone@lns.infn.i [Universita Kore, Erma (Italy)

2010-01-01

Owing the presence of the Coulomb barrier at astrophysically relevant energies, it is very difficult, or sometimes impossible to measure reaction rates for charged particle induced reactions. Moreover due to the presence of the electron screening effect in direct measurements, the relevant nuclear input for astrophysics, i.e. the bare nucleus S(E)-factor, can hardly be extracted. This is why different indirect techniques are being used along with direct measurements. The THM is an unique: indirect technique which allows one to measure reactions cross sections of astrophysical interest down the thermal energies typical of the different scenarios. The basic principle and a review of the main applications of the Trojan Horse Method are given. The applications aiming at the extraction of the bare S{sub b}(E) astrophysical factor and electron screening potentials U{sub e} for several two body processes are discussed.

Laser Techniques on Acoustically Levitated Droplets

Science.gov (United States)

Cannuli, Antonio; Caccamo, Maria Teresa; Castorina, Giuseppe; Colombo, Franco; Magazù, Salvatore

2018-01-01

This work reports the results of an experimental study where laser techniques are applied to acoustically levitated droplets of trehalose aqueous solutions in order to perform spectroscopic analyses as a function of concentration and to test the theoretical diameter law. The study of such systems is important in order to better understand the behaviour of trehalose-synthesizing extremophiles that live in extreme environments. In particular, it will be shown how acoustic levitation, combined with optical spectroscopic instruments allows to explore a wide concentration range and to test the validity of the diameter law as a function of levitation lag time, i.e. the D2 vs t law. On this purpose a direct diameter monitoring by a video camera and a laser pointer was first performed; then the diameter was also evaluated by an indirect measure through an OH/CH band area ratio analysis of collected Raman and Infrared spectra. It clearly emerges that D2 vs t follows a linear trend for about 20 minutes, reaching then a plateau at longer time. This result shows how trehalose is able to avoid total water evaporation, this property being essential for the surviving of organisms under extreme environmental conditions.

Social Dilemmas and Indirect Reciprocity: A systematic review

Directory of Open Access Journals (Sweden)

Cristian Acosta

2014-08-01

Full Text Available Indirect reciprocity is an evolutionary theory of altruism and cooperation in social dilemmas. Its explanation of cooperation incorporates information on the reputation people hold of other people regarding whether they are cooperative or not. This study systematically reviewed the current empirical literature on indirect reciprocity in social dilemma situations. The following databases were consulted: ScienceDirect, EBSCO, and OVID, using has key words "indirect reciprocity" AND "dilemma" OR "cooperation" OR "charity". Twenty-three articles were selected which met the inclusion criteria (papers written in English and studies whose methodology was based on experimental games and the theories, objectives, the main types of samples used, and main results were analyzed. The results show that the games used were the indirect reciprocity and public goods games, which may vary according to the objectives. It was found that reputation is a key variable that helps to promote cooperation. In turn, information on previous cooperation helps to build reputation, which is subsequently involved in the decision to cooperate with others. Finally, we highlight the need for more experimental studies that incorporate other explanatory variables and evaluate them in new contexts.

Biomass Indirect Liquefaction Strategy Workshop Summary Report

Energy Technology Data Exchange (ETDEWEB)

none,

2014-07-01

This report is based on the proceedings of the U.S. Department of Energy Bioenergy Technologies Office Biomass Indirect Liquefaction Strategy Workshop. The workshop, held March 20–21, 2014, in Golden, Colorado, discussed and detailed the research and development needs for biomass indirect liquefaction. Discussions focused on pathways that convert biomass-based syngas (or any carbon monoxide, hydrogen gaseous stream) to liquid intermediates (alcohols or acids) and further synthesize those intermediates to liquid hydrocarbons that are compatible as either a refinery feed or neat fuel.

Detection of rotator cuff lesions with indirect MR angiography

International Nuclear Information System (INIS)

Rudolph, J.; Lorenz, M.; Schroeder, R.; Felix, R.

2000-01-01

Purpose: To determine the value of indirect MR arthrography in lesions of the rotator cuff, prospectively versus arthroscopy. Methods: 63 patients with suspected shoulder pathology were examined: Oblique-coronary and axial T 1 w sequences, axial FLASH-2 D sequences, furthermore oblique-coronary T 2 - and PD-weighted sequences were taken. After intravenous administration of 0.1 mmol Gd-DTPA/kilogram body weight and active motion of the shoulder T 1 w sequences were repeated. Signal intensities (SI) inside the tendon were quantitatively measured by the ROI technique (region-of-interest) and the percentual contrast-enhancement CE was calculated. In 32 patients the results were confirmed by surgical follow-up. Results: The mean SI measured in the supraspinous tendon were higher in lesions (degeneration, impingement, partial and total rupture), before as well as after contrast medium, compared to intact findings (p [de

Evolution of gossip-based indirect reciprocity on a bipartite network

Science.gov (United States)

Giardini, Francesca; Vilone, Daniele

2016-11-01

Cooperation can be supported by indirect reciprocity via reputation. Thanks to gossip, reputations are built and circulated and humans can identify defectors and ostracise them. However, the evolutionary stability of gossip is allegedly undermined by the fact that it is more error-prone that direct observation, whereas ostracism could be ineffective if the partner selection mechanism is not robust. The aim of this work is to investigate the conditions under which the combination of gossip and ostracism might support cooperation in groups of different sizes. We are also interested in exploring the extent to which errors in transmission might undermine the reliability of gossip as a mechanism for identifying defectors. Our results show that a large quantity of gossip is necessary to support cooperation, and that group structure can mitigate the effects of errors in transmission.

Evolution of gossip-based indirect reciprocity on a bipartite network.

Science.gov (United States)

Giardini, Francesca; Vilone, Daniele

2016-11-25

Cooperation can be supported by indirect reciprocity via reputation. Thanks to gossip, reputations are built and circulated and humans can identify defectors and ostracise them. However, the evolutionary stability of gossip is allegedly undermined by the fact that it is more error-prone that direct observation, whereas ostracism could be ineffective if the partner selection mechanism is not robust. The aim of this work is to investigate the conditions under which the combination of gossip and ostracism might support cooperation in groups of different sizes. We are also interested in exploring the extent to which errors in transmission might undermine the reliability of gossip as a mechanism for identifying defectors. Our results show that a large quantity of gossip is necessary to support cooperation, and that group structure can mitigate the effects of errors in transmission.

Detection of antibodies in human serum using trimellityl-erythrocytes: direct and indirect haemagglutination and haemolysis.

Science.gov (United States)

Turner, E S; Pruzansky, J J; Patterson, R; Zeiss, C R; Roberts, M

1980-02-01

Utilizing trimellityl-erythrocytes (TM-E), antibodies were detected in sera of seven workers with trimellitic anhydride (TMA) induced airway syndromes by direct haemagglutination, indirect haemagglutination with anti-human IgG, IgA or IgM or by haemolysis. Detectable levels of antibody were obtained with all three methods. The most sensitive technique was indirect haemagglutination using anti-IgG. When added as an inhibitor, TM-human serum albumin produced a 10- to 800-fold reduction in titres. TM-ovalbumin of similar epitope density was less inhibitory and sodium trimellitate the least inhibitory on a molar basis. All of the assays using haptenized human red cells were also capable of detecting anti-TM antibodies in Rhesus monkeys whose airways had been exposed to TMA. These assays are useful for detecting anti-TM antibodies and may also be adapted to demonstrate antibodies induced against other inhaled haptens in sera of environmentally exposed individuals or in animal models of such exposure.

Indirect Reciprocity : A Field Experiment

NARCIS (Netherlands)

van Apeldoorn, J.; Schram, A.

2016-01-01

Indirect reciprocity involves cooperative acts towards strangers, either in response to their kindness to third parties (downstream) or after receiving kindness from others oneself (upstream). It is considered to be important for the evolution of cooperative behavior amongst humans. Though it has

Neutron-capture Cross Sections from Indirect Measurements

Energy Technology Data Exchange (ETDEWEB)

Escher, J E; Burke, J T; Dietrich, F S; Ressler, J J; Scielzo, N D; Thompson, I J

2011-10-18

Cross sections for compound-nuclear reactions play an important role in models of astrophysical environments and simulations of the nuclear fuel cycle. Providing reliable cross section data remains a formidable task, and direct measurements have to be complemented by theoretical predictions and indirect methods. The surrogate nuclear reactions method provides an indirect approach for determining cross sections for reactions on unstable isotopes, which are difficult or impossible to measure otherwise. Current implementations of the method provide useful cross sections for (n,f) reactions, but need to be improved upon for applications to capture reactions.

42 CFR 412.322 - Indirect medical education adjustment factor.

Science.gov (United States)

2010-10-01

... Payment System for Inpatient Hospital Capital Costs Basic Methodology for Determining the Federal Rate for Capital-Related Costs § 412.322 Indirect medical education adjustment factor. (a) Basic data. CMS.... The indirect teaching adjustment factor equals [e (raised to the power of .2822×the ratio of residents...

Direct and indirect pathways for choosing objects and actions.

Science.gov (United States)

Hikosaka, Okihide; Kim, Hyoung F; Amita, Hidetoshi; Yasuda, Masaharu; Isoda, Masaki; Tachibana, Yoshihisa; Yoshida, Atsushi

2018-02-23

A prominent target of the basal ganglia is the superior colliculus (SC) which controls gaze orientation (saccadic eye movement in primates) to an important object. This 'object choice' is crucial for choosing an action on the object. SC is innervated by the substantia nigra pars reticulata (SNr) which is controlled mainly by the caudate nucleus (CD). This CD-SNr-SC circuit is sensitive to the values of individual objects and facilitates saccades to good objects. The object values are processed differently in two parallel circuits: flexibly by the caudate head (CDh) and stably by the caudate tail (CDt). To choose good objects, we need to reject bad objects. In fact, these contrasting functions are accomplished by the circuit originating from CDt: The direct pathway focuses on good objects and facilitates saccades to them; the indirect pathway focuses on bad objects and suppresses saccades to them. Inactivation of CDt deteriorated the object choice, because saccades to bad objects were no longer suppressed. This suggests that the indirect pathway is important for object choice. However, the direct and indirect pathways for 'object choice', which aim at the same action (i.e., saccade), may not work for 'action choice'. One possibility is that circuits controlling different actions are connected through the indirect pathway. Additional connections of the indirect pathway with brain areas outside the basal ganglia may also provide a wider range of behavioral choice. In conclusion, basal ganglia circuits are composed of the basic direct/indirect pathways and additional connections and thus have acquired multiple functions. © 2018 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Evaluation of marginal and internal gaps of metal ceramic crowns obtained from conventional impressions and casting techniques with those obtained from digital techniques

Directory of Open Access Journals (Sweden)

Rathika Rai

2017-01-01

Full Text Available Background: Accuracy in fit of cast metal restoration has always remained as one of the primary factors in determining the success of the restoration. A well-fitting restoration needs to be accurate both along its margin and with regard to its internal surface. Aim: The aim of the study is to evaluate the marginal fit of metal ceramic crowns obtained by conventional inlay casting wax pattern using conventional impression with the metal ceramic crowns obtained by computer-aided design and computer-aided manufacturing (CAD/CAM technique using direct and indirect optical scanning. Materials and Methods: This in vitro study on preformed custom-made stainless steel models with former assembly that resembles prepared tooth surfaces of standardized dimensions comprised three groups: the first group included ten samples of metal ceramic crowns fabricated with conventional technique, the second group included CAD/CAM-milled direct metal laser sintering (DMLS crowns using indirect scanning, and the third group included DMLS crowns fabricated by direct scanning of the stainless steel model. The vertical marginal gap and the internal gap were evaluated with the stereomicroscope (Zoomstar 4; post hoc Turkey's test was used for statistical analysis. One-way analysis of variance method was used to compare the mean values. Results and Conclusion: Metal ceramic crowns obtained from direct optical scanning showed the least marginal and internal gap when compared to the castings obtained from inlay casting wax and indirect optical scanning. Indirect and direct optical scanning had yielded results within clinically acceptable range.

An improved recommendation algorithm via weakening indirect linkage effect

International Nuclear Information System (INIS)

Chen Guang; Qiu Tian; Shen Xiao-Quan

2015-01-01

We propose an indirect-link-weakened mass diffusion method (IMD), by considering the indirect linkage and the source object heterogeneity effect in the mass diffusion (MD) recommendation method. Experimental results on the MovieLens, Netflix, and RYM datasets show that, the IMD method greatly improves both the recommendation accuracy and diversity, compared with a heterogeneity-weakened MD method (HMD), which only considers the source object heterogeneity. Moreover, the recommendation accuracy of the cold objects is also better elevated in the IMD than the HMD method. It suggests that eliminating the redundancy induced by the indirect linkages could have a prominent effect on the recommendation efficiency in the MD method. (paper)

Does technique matter; a pilot study exploring weighting techniques for a multi-criteria decision support framework.

Science.gov (United States)

van Til, Janine; Groothuis-Oudshoorn, Catharina; Lieferink, Marijke; Dolan, James; Goetghebeur, Mireille

2014-01-01

There is an increased interest in the use of multi-criteria decision analysis (MCDA) to support regulatory and reimbursement decision making. The EVIDEM framework was developed to provide pragmatic multi-criteria decision support in health care, to estimate the value of healthcare interventions, and to aid in priority-setting. The objectives of this study were to test 1) the influence of different weighting techniques on the overall outcome of an MCDA exercise, 2) the discriminative power in weighting different criteria of such techniques, and 3) whether different techniques result in similar weights in weighting the criteria set proposed by the EVIDEM framework. A sample of 60 Dutch and Canadian students participated in the study. Each student used an online survey to provide weights for 14 criteria with two different techniques: a five-point rating scale and one of the following techniques selected randomly: ranking, point allocation, pairwise comparison and best worst scaling. The results of this study indicate that there is no effect of differences in weights on value estimates at the group level. On an individual level, considerable differences in criteria weights and rank order occur as a result of the weight elicitation method used, and the ability of different techniques to discriminate in criteria importance. Of the five techniques tested, the pair-wise comparison of criteria has the highest ability to discriminate in weights when fourteen criteria are compared. When weights are intended to support group decisions, the choice of elicitation technique has negligible impact on criteria weights and the overall value of an innovation. However, when weights are used to support individual decisions, the choice of elicitation technique influences outcome and studies that use dissimilar techniques cannot be easily compared. Weight elicitation through pairwise comparison of criteria is preferred when taking into account its superior ability to discriminate between

Structure and interaction in dense colloidal systems: evaluation of scattering data by the generalized indirect Fourier transformation method

International Nuclear Information System (INIS)

Fritz, Gerhard; Glatter, Otto

2006-01-01

The generalized indirect Fourier transformation (GIFT) technique is a versatile tool for the evaluation of small angle scattering data. It does not depend on models for the size and shape of the particles and requires model assumptions only for the interaction effects that are typically not as sensitive to the details of the assumptions. We review here the development of the technique from its inception, focusing on the included interaction models for hard, charged and attractive spheres, and lamellae. A considerable number of applications has also been reported ranging from surfactants, emulsions, microemulsions, food science, and ceramics to melts and block-copolymers

Techniques used in the exploration of turbidite reservoirs in a frontier setting - Helland Hansen setting, Voering Basin, offshore Mid Norway

Energy Technology Data Exchange (ETDEWEB)

Sanchez-Ferrer, F.; James, S.D.; Lak, B.; Evans, A.M.

1998-12-31

In the 15th Norwegian licensing round there was awarded operation of the Helland Hansen deep water license. Subsurface interpretation commenced towards the end of 1996, following completion of a 1540 km{sup 2} 3-D seismic survey. The main exploration target comprise Turonian to Coniacian turbidite sands within a large fault-bound dip closure. This presentation describes various techniques applied in the exploration of this new turbidite play, with emphasis on the study of the reservoir potential. A methodology of integrated analysis is presented. Through these efforts, a greater understanding of the lithological and depositional models in this non-calibrated area has progressively been achieved. 5 refs., 11 figs.

Indirect Comprehensive Review Board (ICRB). Final Report

International Nuclear Information System (INIS)

1996-12-01

Lockheed Martin Idaho Technologies Company (LMITCO) used a systems engineering approach to take the first step toward defining a requirements baseline for all indirect work at the Idaho National Engineering Laboratory. The intent of this effort was to define the requirements for indirect work, identify the activities necessary to meet the requirements, and to produce defensible cost estimates for the work. The result of this effort is a scrubbed-down, defensible budget for all indirect work in FY 1997. Buying power for each dollar of direct work was increased by $.02. Recommendations are identified for improvements to this process in FY 1998. The purpose of this report is twofold. First is to report the final results of the 1996 ICRB process, and second is to document the process used such that incremental improvements may be made in future years. Objectives, processes, and approaches are described to provide a trail for future boards. Appendices contain copies of board composition, documentation of the process, as well as the actual training materials

Interactive indirect illumination using adaptive multiresolution splatting.

Science.gov (United States)

Nichols, Greg; Wyman, Chris

2010-01-01

Global illumination provides a visual richness not achievable with the direct illumination models used by most interactive applications. To generate global effects, numerous approximations attempt to reduce global illumination costs to levels feasible in interactive contexts. One such approximation, reflective shadow maps, samples a shadow map to identify secondary light sources whose contributions are splatted into eye space. This splatting introduces significant overdraw that is usually reduced by artificially shrinking each splat's radius of influence. This paper introduces a new multiresolution approach for interactively splatting indirect illumination. Instead of reducing GPU fill rate by reducing splat size, we reduce fill rate by rendering splats into a multiresolution buffer. This takes advantage of the low-frequency nature of diffuse and glossy indirect lighting, allowing rendering of indirect contributions at low resolution where lighting changes slowly and at high-resolution near discontinuities. Because this multiresolution rendering occurs on a per-splat basis, we can significantly reduce fill rate without arbitrarily clipping splat contributions below a given threshold-those regions simply are rendered at a coarse resolution.

Indirect carotid cavernous fistula mimicking ocular myasthenia.

Science.gov (United States)

Leishangthem, Lakshmi; Satti, Sudhakar Reddy

2017-10-19

71-year-old woman with progressive left-sided, monocular diplopia and ptosis. Her symptoms mimicked ocular myasthenia, but she had an indirect carotid cavernous fistula (CCF). She was diagnosed with monocular myasthenia gravis (negative acetylcholinesterase antibody) after a positive ice test and started on Mestinon and underwent a thymectomy complicated by a brachial plexus injury. Months later, she developed left-sided proptosis and ocular bruit. She was urgently referred to neuro-interventional surgery and was diagnosed with an indirect high-flow left CCF, which was treated with Onyx liquid and platinum coil embolisation. Mestinon was discontinued. Her ophthalmic symptoms resolved. However, she was left with a residual left arm and hand hemiparesis and dysmetria secondary to a brachial plexus injury. Indirect CCF usually can present with subtle and progressive symptoms leading to delayed diagnosis or misdiagnosis. It is important for ophthalmologists to consider this differential in a patient with progressive ocular symptoms. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

The Indirect Costs of Financial Distress in Indonesia

Directory of Open Access Journals (Sweden)

Wijantini Wijantini

2007-06-01

Full Text Available This paper presents quantitative estimates of the indirect cost of financial distress and its determinants. In order to measure the cost, this study estimates the annualized changes in industry-adjusted operation profit and sales from a year before the onset of distress to the resolution year. Using those approaches, the median of indirect financial distress cost is estimated between three and 11 percent annually. To the extent that the direct cost of financial distress reduces reported operating income, the estimated costs are overstated. The simple regressions analysis suggest that the indirect cost of financial distress significantly increases with size, leverage, number of creditors, and poor industry performance, but is not related to degree of bank loan reliance. The findings provide a weak support for the financial distress theory which suggests that conflicts of interest render the costs of financial distress.

The Use of Electromagnetic Induction Techniques for Soil Mapping

Science.gov (United States)

Brevik, Eric C.; Doolittle, Jim

2015-04-01

Soils have high natural spatial variability. This has been recognized for a long time, and many methods of mapping that spatial variability have been investigated. One technique that has received considerable attention over the last ~30 years is electromagnetic induction (EMI). Particularly when coupled with modern GPS and GIS systems, EMI techniques have allowed the rapid and relatively inexpensive collection of large spatially-related data sets that can be correlated to soil properties that either directly or indirectly influence electrical conductance in the soil. Soil electrical conductivity is directly controlled by soil water content, soluble salt content, clay content and mineralogy, and temperature. A wide range of indirect controls have been identified, such as soil organic matter content and bulk density; both influence water relationships in the soil. EMI techniques work best in areas where there are large changes in one soil property that influences soil electrical conductance, and don't work as well when soil properties that influence electrical conductance are largely homogenous. This presentation will present examples of situations where EMI techniques were successful as well as a couple of examples of situations where EMI was not so useful in mapping the spatial variability of soil properties. Reasons for both the successes and failures will be discussed.

How good is technetium-99m mercaptoacetyltriglycine indirect cystography?

International Nuclear Information System (INIS)

Sadeleer, C. de; Boe, V. de; Keuppens, F.; Desprechins, B.; Verboven, M.; Piepsz, A.

1994-01-01

The aim of the present study was to estimate the sensitivity of indirect radionuclide cystography (IRC) performed with technetium-99m mercaptoacetyltriglycine (MAG3), in comparison with the micturition cystourethrography (MCUG) and direct radionuclide cystography (DRC), for the diagnosis of vesicoureteric reflux. Two groups of patients were selected: group I comprised 40 children who underwent IRC during the acute phase of urinary tract infection and an MCUG 6 weeks later; group II comprised 42 (other) children with known reflux, who underwent IRC and DRC during follow-up. Taking as the reference the total number of refluxing kidneys detected by means of any cystographic technique, 99m Tc-MAG3 ICR missed two-thirds of the refluxing kidneys. Most of the small refluxes were missed, but so too were 50% of the major refluxes. Taking as the reference 99m Tc dimercaptosuccinic acid (DMSA) scintigraphy, MCUG detected 91% of the patients with DMSA abnormalities on at least one kidney, DRC detected 95%, and IRC detected 46% and 43% respectively, in groups I and II. The use of 99m Tc-MAG3 IRC as the sole technique for the detection of vesicoureteric reflux gives rise to an unacceptable number of false-negative results. (orig.)

Exploring miniature insect brains using micro-CT scanning techniques

Science.gov (United States)

Smith, Dylan B.; Bernhardt, Galina; Raine, Nigel E.; Abel, Richard L.; Sykes, Dan; Ahmed, Farah; Pedroso, Inti; Gill, Richard J.

2016-01-01

The capacity to explore soft tissue structures in detail is important in understanding animal physiology and how this determines features such as movement, behaviour and the impact of trauma on regular function. Here we use advances in micro-computed tomography (micro-CT) technology to explore the brain of an important insect pollinator and model organism, the bumblebee (Bombus terrestris). Here we present a method for accurate imaging and exploration of insect brains that keeps brain tissue free from trauma and in its natural stereo-geometry, and showcase our 3D reconstructions and analyses of 19 individual brains at high resolution. Development of this protocol allows relatively rapid and cost effective brain reconstructions, making it an accessible methodology to the wider scientific community. The protocol describes the necessary steps for sample preparation, tissue staining, micro-CT scanning and 3D reconstruction, followed by a method for image analysis using the freeware SPIERS. These image analysis methods describe how to virtually extract key composite structures from the insect brain, and we demonstrate the application and precision of this method by calculating structural volumes and investigating the allometric relationships between bumblebee brain structures. PMID:26908205

Data-Foraging-Oriented Reconnaissance Based on Bio-Inspired Indirect Communication for Aerial Vehicles

Directory of Open Access Journals (Sweden)

Josué Castañeda Cisneros

2017-07-01

Full Text Available In recent years, aerial vehicles have allowed exploring scenarios with harsh conditions. These can conduct reconnaissance tasks in areas that change periodically and have a high spatial and temporal resolution. The objective of a reconnaissance task is to survey an area and retrieve strategic information. The aerial vehicles, however, have inherent constraints in terms of energy and transmission range due to their mobility. Despite these constraints, the Data Foraging problem requires the aerial vehicles to exchange information about profitable data sources. In Data Foraging, establishing a single path is not viable because of dynamic conditions of the environment. Thus, reconnaissance must be focused on periodically searching profitable environmental data sources, as some animals perform foraging. In this work, a data-foraging-oriented reconnaissance algorithm based on bio-inspired indirect communication for aerial vehicles is presented. The approach establishes several paths that overlap to identify valuable data sources. Inspired by the stigmergy principle, the aerial vehicles indirectly communicate through artificial pheromones. The aerial vehicles traverse the environment using a heuristic algorithm that uses the artificial pheromones as feedback. The solution is formally defined and mathematically evaluated. In addition, we show the viability of the algorithm by simulations which have been tested through various statistical hypothesis.

Gyro Drift Correction for An Indirect Kalman Filter Based Sensor Fusion Driver

Directory of Open Access Journals (Sweden)

Chan-Gun Lee

2016-06-01

Full Text Available Sensor fusion techniques have made a significant contribution to the success of the recently emerging mobile applications era because a variety of mobile applications operate based on multi-sensing information from the surrounding environment, such as navigation systems, fitness trackers, interactive virtual reality games, etc. For these applications, the accuracy of sensing information plays an important role to improve the user experience (UX quality, especially with gyroscopes and accelerometers. Therefore, in this paper, we proposed a novel mechanism to resolve the gyro drift problem, which negatively affects the accuracy of orientation computations in the indirect Kalman filter based sensor fusion. Our mechanism focuses on addressing the issues of external feedback loops and non-gyro error elements contained in the state vectors of an indirect Kalman filter. Moreover, the mechanism is implemented in the device-driver layer, providing lower process latency and transparency capabilities for the upper applications. These advances are relevant to millions of legacy applications since utilizing our mechanism does not require the existing applications to be re-programmed. The experimental results show that the root mean square errors (RMSE before and after applying our mechanism are significantly reduced from 6.3 × 10−1 to 5.3 × 10−7, respectively.

Third European Company Survey – Direct and indirect employee participation

NARCIS (Netherlands)

Akkerman, Agnes; Sluiter, Roderick; Jansen, Giedo

2015-01-01

This report studies practices in EU establishments for direct and indirect employee participation in decision-making. Indirect employee participation is the involvement of employee representatives in decision-making processes, while direct employee participation describes direct interaction between

Neutron-capture cross sections from indirect measurements

Directory of Open Access Journals (Sweden)

Scielzo N.D.

2012-02-01

Full Text Available Cross sections for compound-nuclear reactions reactions play an important role in models of astrophysical environments and simulations of the nuclear fuel cycle. Providing reliable cross section data remains a formidable task, and direct measurements have to be complemented by theoretical predictions and indirect methods. The surrogate nuclear reactions method provides an indirect approach for determining cross sections for reactions on unstable isotopes, which are difficult or impossible to measure otherwise. Current implementations of the method provide useful cross sections for (n,f reactions, but need to be improved upon for applications to capture reactions.

U.S. DOE indirect coal liquefaction program: An overview

Energy Technology Data Exchange (ETDEWEB)

Shen, J.; Schmetz, E.; Winslow, J.; Tischer, R. [Dept. of Energy, Germantown, MD (United States); Srivastava, R.

1997-12-31

Coal is the most abundant domestic energy resource in the United States. The Fossil Energy Organization within the US Department of Energy (DOE) has been supporting a coal liquefaction program to develop improved technologies to convert coal to clean and cost-effective liquid fuels to complement the dwindling supply of domestic petroleum crude. The goal of this program is to produce coal liquids that are competitive with crude at $20 to $25 per barrel. Indirect and direct liquefaction routes are the two technologies being pursued under the DOE coal liquefaction program. This paper will give an overview of the DOE indirect liquefaction program. More detailed discussions will be given to the F-T diesel and DME fuels which have shown great promises as clean burning alternative diesel fuels. The authors also will briefly discuss the economics of indirect liquefaction and the hurdles and opportunities for the early commercial deployment of these technologies. Discussions will be preceded by two brief reviews on the liquid versus gas phase reactors and the natural gas versus coal based indirect liquefaction.

Indirect searches for dark matter

Indian Academy of Sciences (India)

The current status of indirect searches for dark matter has been reviewed in a schematic way here. The main relevant experimental results of the recent years have been listed and the excitements and disappointments that their phenomenological interpretations in terms of almost-standard annihilating dark matter have ...

Amygdaloid projections to the ventral striatum in mice: direct and indirect chemosensory inputs to the brain reward system.

Science.gov (United States)

Novejarque, Amparo; Gutiérrez-Castellanos, Nicolás; Lanuza, Enrique; Martínez-García, Fernando

2011-01-01

Rodents constitute good models for studying the neural basis of sociosexual behavior. Recent findings in mice have revealed the molecular identity of the some pheromonal molecules triggering intersexual attraction. However, the neural pathways mediating this basic sociosexual behavior remain elusive. Since previous work indicates that the dopaminergic tegmento-striatal pathway is not involved in pheromone reward, the present report explores alternative pathways linking the vomeronasal system with the tegmento-striatal system (the limbic basal ganglia) by means of tract-tracing experiments studying direct and indirect projections from the chemosensory amygdala to the ventral striato-pallidum. Amygdaloid projections to the nucleus accumbens, olfactory tubercle, and adjoining structures are studied by analyzing the retrograde transport in the amygdala from dextran amine and fluorogold injections in the ventral striatum, as well as the anterograde labeling found in the ventral striato-pallidum after dextran amine injections in the amygdala. This combination of anterograde and retrograde tracing experiments reveals direct projections from the vomeronasal cortex to the ventral striato-pallidum, as well as indirect projections through different nuclei of the basolateral amygdala. Direct projections innervate mainly the olfactory tubercle and the islands of Calleja, whereas indirect projections are more widespread and reach the same structures and the shell and core of nucleus accumbens. These pathways are likely to mediate innate responses to pheromones (direct projections) and conditioned responses to associated chemosensory and non-chemosensory stimuli (indirect projections). Comparative studies indicate that similar connections are present in all the studied amniote vertebrates and might constitute the basic circuitry for emotional responses to conspecifics in most vertebrates, including humans.

Study and development of indirect force measurement. Application to the identification of diesel engine internal sources; Etude et developpement de la mesure indirecte d'efforts. Application a l'identification des sources internes d'un moteur Diesel

Energy Technology Data Exchange (ETDEWEB)

Leclere, Q.

2003-12-15

The aim of this work is to develop a diagnostic method allowing to quantify vibratory sources of stationary operating machines from measurements. The direct measurement of sources using a force sensor is often difficult to obtain, not to say impossible. Thus, their estimation is assessed from both operating response measurements and a transfer model of the structure. Concerning the method, several original developments are put forward, especially to optimise the technique when the machine structure has an heterogeneous dynamic behaviour. Moreover, a reliability indicator of the force estimation is introduced, based on the comparison between different approaches of the transfer system inversion. The reliability of results are indeed a crucial point for indirect force measurement, because the technique is known to be very sensitive to different types of errors (measurement noise, model error). The method is applied to the identification of Diesel engine internal sources. A special attention is paid to the construction of the transfer model, estimated by both experimental and numerical approaches. Identified forces are compared to excitations computed through a simple drive train model. The comparison allows to underline some model deficiencies as well as the relative robustness of the method. A source ranking operation is realized in order to present the interest of the indirect force measurement results. (author)

Direct and indirect detection of supersymmetric dark matter; Detection directe et indirecte de matiere sombre supersymetrique

Energy Technology Data Exchange (ETDEWEB)

Mayet, F

2001-09-01

A substantial body of astrophysical evidence supports the existence of non-baryonic dark matter in the universe. One of the leading dark matter candidates is the neutralino predicted by the supersymmetric extensions of the standard model of particle physics. Different detectors have been designed for the detection, either indirect or direct, of the neutralino. Related to indirect detection, the present work has been performed in the context of the AMS experiment. A precursor version of the spectrometer was flown on the space shuttle Discovery in June 1998. The detector included an Aerogel Threshold Cherenkov counter (ATC) to identify antiprotons, whose spectrum may be used to infer a neutralino signal. The analysis of the ATC data is presented including an evaluation of the flight performance and a description of the optimization of the antiproton selection. An antiproton analysis is also reported. A phenomenological study allows us to investigate the discovery potential of this indirect method. This thesis also includes the development of a new detector (MACHe3) designed for direct neutralino search using a superfluid {sup 3}He bolometer operated at ultra low temperatures. The data analysis of the prototype cell is presented. A Monte Carlo simulation has been developed, in order to optimize the detector design for direct neutralino search. These results are compared with theoretical predictions of supersymmetric models, thus highlighting the discovery potential of this detector and its complementarity with existing devices. (author)

A norm knockout method on indirect reciprocity to reveal indispensable norms

Science.gov (United States)

Yamamoto, Hitoshi; Okada, Isamu; Uchida, Satoshi; Sasaki, Tatsuya

2017-03-01

Although various norms for reciprocity-based cooperation have been suggested that are evolutionarily stable against invasion from free riders, the process of alternation of norms and the role of diversified norms remain unclear in the evolution of cooperation. We clarify the co-evolutionary dynamics of norms and cooperation in indirect reciprocity and also identify the indispensable norms for the evolution of cooperation. Inspired by the gene knockout method, a genetic engineering technique, we developed the norm knockout method and clarified the norms necessary for the establishment of cooperation. The results of numerical investigations revealed that the majority of norms gradually transitioned to tolerant norms after defectors are eliminated by strict norms. Furthermore, no cooperation emerges when specific norms that are intolerant to defectors are knocked out.

The Indirect Costs of Financial Distress in Indonesia

OpenAIRE

Wijantini, Wijantini

2007-01-01

This paper presents quantitative estimates of the indirect cost of financial distress and its determinants. In order to measure the cost, this study estimates the annualized changes in industry-adjusted operation profit and sales from a year before the onset of distress to the resolution year. Using those approaches, the median of indirect financial distress cost is estimated between three and 11 percent annually. To the extent that the direct cost of financial distress reduces reported opera...

Positive indirect interactions between neighboring plant species via a lizard pollinator.

OpenAIRE

Hansen, D M; Kiesbüy, H C; Jones, C G; Müller, C B

2007-01-01

In natural communities, species are embedded in networks of direct and indirect interactions. Most studies on indirect interactions have focused on how they affect predator-prey or competitive relationships. However, it is equally likely that indirect interactions play an important structuring role in mutualistic relationships in a natural community. We demonstrate experimentally that on a small spatial scale, dense thickets of endemic Pandanus plants have a strong positive trait-mediated ind...

Spatially indirect excitons in coupled quantum wells

Energy Technology Data Exchange (ETDEWEB)

Lai, Chih-Wei Eddy [Univ. of California, Berkeley, CA (United States)

2004-03-01

Microscopic quantum phenomena such as interference or phase coherence between different quantum states are rarely manifest in macroscopic systems due to a lack of significant correlation between different states. An exciton system is one candidate for observation of possible quantum collective effects. In the dilute limit, excitons in semiconductors behave as bosons and are expected to undergo Bose-Einstein condensation (BEC) at a temperature several orders of magnitude higher than for atomic BEC because of their light mass. Furthermore, well-developed modern semiconductor technologies offer flexible manipulations of an exciton system. Realization of BEC in solid-state systems can thus provide new opportunities for macroscopic quantum coherence research. In semiconductor coupled quantum wells (CQW) under across-well static electric field, excitons exist as separately confined electron-hole pairs. These spatially indirect excitons exhibit a radiative recombination time much longer than their thermal relaxation time a unique feature in direct band gap semiconductor based structures. Their mutual repulsive dipole interaction further stabilizes the exciton system at low temperature and screens in-plane disorder more effectively. All these features make indirect excitons in CQW a promising system to search for quantum collective effects. Properties of indirect excitons in CQW have been analyzed and investigated extensively. The experimental results based on time-integrated or time-resolved spatially-resolved photoluminescence (PL) spectroscopy and imaging are reported in two categories. (i) Generic indirect exciton systems: general properties of indirect excitons such as the dependence of exciton energy and lifetime on electric fields and densities were examined. (ii) Quasi-two-dimensional confined exciton systems: highly statistically degenerate exciton systems containing more than tens of thousands of excitons within areas as small as (10 micrometer)² were

and Indigenous Indirect Enzyme-Linked Immunosorbent Assay

Directory of Open Access Journals (Sweden)

Annapurna S. Agasthya

2012-01-01

Full Text Available Brucellosis is one of the most important reemerging zoonoses in many countries. Brucellosis is caused by Gram-negative coccobacillus belonging to genus Brucella. Human brucellosis often makes the diagnosis difficult. The symptoms and clinical signs most commonly reported are fever, fatigue, malaise, chills, sweats headaches, myalgia, arthralgia, and weight loss. Some cases have been presented with only joint pain, lower backache, and involuntary limb movement, burning feet, or ischemic heart attacks. The focus of this work was to develop a highly sensitive and specific indirect ELISA by using smooth lipopolysaccharide antigen of Brucella abortus 99 to detect anti-Brucella antibodies at Project Directorate on Animal Disease Monitoring and Surveillance. Serum samples collected from 652 individuals in whom fever was not the major symptom but the complaint was of joint pain, headache, lower backache, and so forth, were screened by Rose Bengal plate agglutination test (RBPT and standard tube agglutination test (STAT. Subsequent testing of sera by indigenous indirect ELISA detected 20 samples positive (3.6% seroprevalence, and indirect ELISA was found to be more sensitive than RBPT and STAT. The seroprevalence in South Karnataka was 2.14%, and in North Karnataka it was 0.92%.

Indirect Competitive Enzyme-Linked Immunosorbent Assay (ELISA).

Science.gov (United States)

Kohl, Thomas O; Ascoli, Carl A

2017-07-05

The indirect competitive ELISA (indirect cELISA) pits plate-immobilized antigen against antigens in solution for binding to antigen-specific antibody. The antigens in solution are in the test sample and are first incubated with antigen-specific antibody. These antibody-antigen complexes are then added to microtiter plates whose wells have been coated with purified antigen. The wells are washed to remove unbound antigen-antibody complexes and free antigen. A reporter-labeled secondary antibody is then added followed by the addition of substrate. Substrate hydrolysis yields a signal that is inversely proportional to antigen concentration within the sample. This is because when antigen concentration is high in the test sample, most of the antibody is bound before adding the solution to the plate. Most of the antibody remains in solution (as complexes) and is thus washed away before the addition of the reporter-labeled secondary antibody and substrate. Thus, the higher the antigen concentration in the test sample, the weaker the resultant signal in the detection step. The indirect cELISA is often used for competitive detection and quantification of antibodies against viral diseases in biological samples. © 2017 Cold Spring Harbor Laboratory Press.

Review of current research, problems and future trends with regard to geochemical techniques for uranium exploration and recent developments in radon detection

International Nuclear Information System (INIS)

De Wet, W.J.

1984-01-01

The review deals with the need for knowledge of uranium geology and exploration techniques. The review mainly focuses on radon techniques and closely related aspects. The use of radon as a prospecting tool is primarily based on the fact that it is an inert gas, and threfore, has the ability to migrate through cracks and porous media. The methods used in radon prospecting are based on the detection of α or γ-radon produced during the radioactive decay of Rn and/or Rn decay daughter isotopes. The methods can be described as either active or passive. The active methods involve pumping of soil gas from a narrow hole drilled in the ground and suitably covered, into or through a detector instrument, whereas the passive methods register Rn concentrations in the ground under natural conditions. In uranium exploration the aim is to distinguish areas with enhanced radon concentrations in relation to background levels

Explicit calculation of indirect global warming potentials for halons using atmospheric models

Directory of Open Access Journals (Sweden)

D. J. Wuebbles

2009-11-01

Full Text Available The concept of Global Warming Potentials (GWPs has been extensively used in policy consideration as a relative index for comparing the climate impact of an emitted greenhouse gas (GHG, relative to carbon dioxide with equal mass emissions. Ozone depletion due to emission of chlorinated or brominated halocarbons leads to cooling of the climate system in the opposite direction to the direct warming contribution by halocarbons as GHGs. This cooling is a key indirect effect of the halocarbons on climatic radiative forcing, which is accounted for by indirect GWPs. With respect to climate, it is critical to understand net influences considering direct warming and indirect cooling effects especially for Halons due to the greater ozone-depleting efficiency of bromine over chlorine. Until now, the indirect GWPs have been calculated using a parameterized approach based on the concept of Equivalent Effective Stratospheric Chlorine (EESC and the observed ozone depletion over the last few decades. As a step towards obtaining indirect GWPs through a more robust approach, we use atmospheric models to explicitly calculate the indirect GWPs of Halon-1211 and Halon-1301 for a 100-year time horizon. State-of-the-art global chemistry-transport models (CTMs were used as the computational tools to derive more realistic ozone depletion changes caused by an added pulse emission of the two major Halons at the surface. The radiative forcings on climate from the ozone changes have been calculated for indirect GWPs using an atmospheric radiative transfer model (RTM. The simulated temporal variations of global average total column Halons after a pulse perturbation follow an exponential decay with an e-folding time which is consistent with the expected chemical lifetimes of the Halons. Our calculated indirect GWPs for the two Halons are much smaller than those from past studies but are within a single standard deviation of WMO (2007 values and the direct GWP values derived

Thermal measurements and inverse techniques

CERN Document Server

Orlande, Helcio RB; Maillet, Denis; Cotta, Renato M

2011-01-01

With its uncommon presentation of instructional material regarding mathematical modeling, measurements, and solution of inverse problems, Thermal Measurements and Inverse Techniques is a one-stop reference for those dealing with various aspects of heat transfer. Progress in mathematical modeling of complex industrial and environmental systems has enabled numerical simulations of most physical phenomena. In addition, recent advances in thermal instrumentation and heat transfer modeling have improved experimental procedures and indirect measurements for heat transfer research of both natural phe

Evidence of indirect gap in monolayer WSe2

KAUST Repository

Hsu, Wei-Ting

2017-10-09

Monolayer transition metal dichalcogenides, such as MoS2 and WSe2, have been known as direct gap semiconductors and emerged as new optically active materials for novel device applications. Here we reexamine their direct gap properties by investigating the strain effects on the photoluminescence of monolayer MoS2 and WSe2. Instead of applying stress, we investigate the strain effects by imaging the direct exciton populations in monolayer WSe2–MoS2 and MoSe2–WSe2 lateral heterojunctions with inherent strain inhomogeneity. We find that unstrained monolayer WSe2 is actually an indirect gap material, as manifested in the observed photoluminescence intensity–energy correlation, from which the difference between the direct and indirect optical gaps can be extracted by analyzing the exciton thermal populations. Our findings combined with the estimated exciton binding energy further indicate that monolayer WSe2 exhibits an indirect quasiparticle gap, which has to be reconsidered in further studies for its fundamental properties and device applications.

Direct and indirect effects of body weight on adult wages.

Science.gov (United States)

Han, Euna; Norton, Edward C; Powell, Lisa M

2011-12-01

Previous estimates of the association between body weight and wages in the literature have been conditional on education and occupation. In addition to the effect of current body weight status (body mass index (BMI) or obesity) on wages, this paper examines the indirect effect of body weight status in the late-teenage years on wages operating through education and occupation choice. Using the National Longitudinal Survey of Youth 1979 data, for women, we find that a one-unit increase in BMI is directly associated with 1.83% lower hourly wages whereas the indirect BMI wage penalty is not statistically significant. Neither a direct nor an indirect BMI wage penalty is found for men. However, results based on clinical weight classification reveal that the indirect wage penalty occurs to a larger extent at the upper tail of the BMI distribution for both men and women via the pathways of education and occupation outcomes. Late-teen obesity is indirectly associated with 3.5% lower hourly wages for both women and men. These results are important because they imply that the total effect of obesity on wages is significantly larger than has been estimated in previous cross-sectional studies. 2011 Elsevier B.V. All rights reserved.

Supporting Risk Assessment: Accounting for Indirect Risk to Ecosystem Components.

Directory of Open Access Journals (Sweden)

Cathryn Clarke Murray

Full Text Available The multi-scalar complexity of social-ecological systems makes it challenging to quantify impacts from human activities on ecosystems, inspiring risk-based approaches to assessments of potential effects of human activities on valued ecosystem components. Risk assessments do not commonly include the risk from indirect effects as mediated via habitat and prey. In this case study from British Columbia, Canada, we illustrate how such "indirect risks" can be incorporated into risk assessments for seventeen ecosystem components. We ask whether (i the addition of indirect risk changes the at-risk ranking of the seventeen ecosystem components and if (ii risk scores correlate with trophic prey and habitat linkages in the food web. Even with conservative assumptions about the transfer of impacts or risks from prey species and habitats, the addition of indirect risks in the cumulative risk score changes the ranking of priorities for management. In particular, resident orca, Steller sea lion, and Pacific herring all increase in relative risk, more closely aligning these species with their "at-risk status" designations. Risk assessments are not a replacement for impact assessments, but-by considering the potential for indirect risks as we demonstrate here-they offer a crucial complementary perspective for the management of ecosystems and the organisms within.

Supporting Risk Assessment: Accounting for Indirect Risk to Ecosystem Components

Science.gov (United States)

Mach, Megan E.; Martone, Rebecca G.; Singh, Gerald G.; O, Miriam; Chan, Kai M. A.

2016-01-01

The multi-scalar complexity of social-ecological systems makes it challenging to quantify impacts from human activities on ecosystems, inspiring risk-based approaches to assessments of potential effects of human activities on valued ecosystem components. Risk assessments do not commonly include the risk from indirect effects as mediated via habitat and prey. In this case study from British Columbia, Canada, we illustrate how such “indirect risks” can be incorporated into risk assessments for seventeen ecosystem components. We ask whether (i) the addition of indirect risk changes the at-risk ranking of the seventeen ecosystem components and if (ii) risk scores correlate with trophic prey and habitat linkages in the food web. Even with conservative assumptions about the transfer of impacts or risks from prey species and habitats, the addition of indirect risks in the cumulative risk score changes the ranking of priorities for management. In particular, resident orca, Steller sea lion, and Pacific herring all increase in relative risk, more closely aligning these species with their “at-risk status” designations. Risk assessments are not a replacement for impact assessments, but—by considering the potential for indirect risks as we demonstrate here—they offer a crucial complementary perspective for the management of ecosystems and the organisms within. PMID:27632287

Bioelectrochemical Systems for Indirect Biohydrogen Production

KAUST Repository

Regan, John M.; Yan, Hengjing

2014-01-01

by exoelectrogens at the anode. As an indirect approach to biohydrogen production, these systems are not subject to the hydrogen yield constraints of fermentative processes and have been proven to work with virtually any biodegradable organic substrate

Special considerations regarding indirect expropriation in international economic law

Directory of Open Access Journals (Sweden)

Laura-Cristiana Spătaru-Negură

2017-12-01

Full Text Available The right to property is a human right that has to be respected so that if the property of a natural or legal person is taken over, the respective person has to be compensated. The right of a state to control the economic business is one of the rights sustained and exercised by the states on a constant basis. This reflects the inherent sovereignty of a state to control its people, incidents and objects found on its territory. Between these rights, the situation of indirect expropriation appears which has been described in the doctrine as being very abstract and rigid, big lacunae existing. The sense of the indirect expropriation and of the international investors’ protection against the indirect expropriation is very ambiguous. Using different methods specific to scientific analyse of the legal phenomenon (e.g. the logical method, the comparative method, the historical method and the quantitative methods, we consider that through this paper we can reach certain results that could be interesting for any legal practitioner or theoretician, this paper intending to present the most relevant cases that could amount to indirect expropriation.

Do infants detect indirect reciprocity?

Science.gov (United States)

Meristo, Marek; Surian, Luca

2013-10-01

In social interactions involving indirect reciprocity, agent A acts prosocially towards B and this prompts C to act prosocially towards A. This happens because A's actions enhanced its reputation in the eyes of third parties. Indirect reciprocity may have been of central importance in the evolution of morality as one of the major mechanisms leading to the selection of helping and fair attitudes. Here we show that 10-month-old infants expect third parties to act positively towards fair donors who have distributed attractive resources equally between two recipients, rather than toward unfair donors who made unequal distributions. Infants' responses were dependent on the reciprocator's perceptual exposure to previous relevant events: they expected the reciprocator to reward the fair donor only when it had seen the distributive actions performed by the donors. We propose that infants were able to generate evaluations of agents that were based on the fairness of their distributive actions and to generate expectations about the social preferences of informed third parties. Copyright © 2013 Elsevier B.V. All rights reserved.

Geothermal Exploration of Newberry Volcano, Oregon

Energy Technology Data Exchange (ETDEWEB)

Waibel, Albert F. [Columbia Geoscience, Pasco, WA (United States); Frone, Zachary S. [Southern Methodist Univ., Dallas, TX (United States); Blackwell, David D. [Southern Methodist Univ., Dallas, TX (United States)

2014-12-01

Davenport Newberry (Davenport) has completed 8 years of exploration for geothermal energy on Newberry Volcano in central Oregon. Two deep exploration test wells were drilled by Davenport on the west flank of the volcano, one intersected a hydrothermal system; the other intersected isolated fractures with no hydrothermal interconnection. Both holes have bottom-hole temperatures near or above 315°C (600°F). Subsequent to deep test drilling an expanded exploration and evaluation program was initiated. These efforts have included reprocessing existing data, executing multiple geological, geophysical, geochemical programs, deep exploration test well drilling and shallow well drilling. The efforts over the last three years have been made possible through a DOE Innovative Exploration Technology (IET) Grant 109, designed to facilitate innovative geothermal exploration techniques. The combined results of the last 8 years have led to a better understanding of the history and complexity of Newberry Volcano and improved the design and interpretation of geophysical exploration techniques with regard to blind geothermal resources in volcanic terrain.

Indirect genetic effects and kin recognition

DEFF Research Database (Denmark)

Alemu, Setegn Worku; Berg, Peer; Janss, Luc

2014-01-01

Social interactions among individuals are widespread, both in natural and domestic populations. As a result, trait values of individuals may be affected by genes in other individuals, a phenomenon known as indirect genetic effects (IGEs). IGEs can be estimated using linear mixed models. The tradi......Social interactions among individuals are widespread, both in natural and domestic populations. As a result, trait values of individuals may be affected by genes in other individuals, a phenomenon known as indirect genetic effects (IGEs). IGEs can be estimated using linear mixed models...... present a reduced model that yields estimates of the total heritable effects on kin, on non-kin and on all social partners of an individual, as well as the total heritable variance for response to selection. Finally we discuss the consequences of analysing data in which IGEs depend on relatedness using...

Indirect pulp capping in primary molar using glass ionomer cements

Directory of Open Access Journals (Sweden)

Murtia Metalita

2014-12-01

Full Text Available Background: Indirect pulp capping in primary teeth, however, is more rarely conducted than permanent teeth, since it thought to have low impact and most suggestion is for taking caries lesion aggressively on primary teeth. Purpose: The study was aimed to evaluate the subjective complaint, clinical symptom, and radiographic appearance of indirect pulp capping treatment using glass ionomers cements in primary molar. Methods: Sixteen children in range of age 6 to 8 years old, who visited Clinic of Pediatric Dentistry Universitas Airlangga Dental Hospital, Surabaya Indonesia, were the subject of study. They had one occlusal dental caries on one side of maxillary or mandibular primary molar with the diagnose of pulpitis reversible. The experimental group, had indirect pulp capping treatment with glass ionomer cements (GC Fuji VII®, while the control group, had indirect pulp capping treatment with calcium hydroxide (Metapaste. Each group was filled with GC Fuji IX® as permanent restoration. After one week, one month, and three months later, the observations were made on subjective complaint, clinical symptom, and radiographic appearance. Results: The results showed no subjective complaint such as pain or problem on mastication; no negative clinical symptoms such as pain on palpation, gingivitis or periodontitis, and abnormal tooth mobility; no negative radiographic appearance such as pathological apical radioluscency, internal or external resorbtion, and change of ligament periodontal widthafter the treatment. Conclusion: The study suggested that indirect pulp capping treatment using glass ionomer cement materials on primary teeth might be considered to be the treatment choice.Latar belakang: Indirect pulp capping pada gigi sulung lebih jarang dilakukan dibandingkan gigi permanen, karena dianggap memiliki dampak yang rendah dan sebagian besar menyarankan untuk mengambil lesi karies secara agresif pada gigi sulung. Tujuan: Penelitian ini bertujuan

exploring traditional glass bead making techniques in jewellery

African Journals Online (AJOL)

User

Glass bead making techniques and their mass production will help the individual ... communicate cultural values in a symbolic lan- guage which ..... Surface of most of the new beads were rough ... tourism potential to be developed further to.

Optimization of the indirect at neutron activation technique for the determination of boron in aqueous solutions

International Nuclear Information System (INIS)

Luz, L.C.Q.P. da.

1984-01-01

The purpose of this work was the development of an instrumental method for the optimization of the indirect neutron activation analysis of boron in aqueous solutions. The optimization took into account the analytical parameters under laboratory conditions: activation carried out with a 241 Am/Be neutron source and detection of the activity induced in vanadium with two NaI(Tl) gamma spectrometers. A calibration curve was thus obtained for a concentration range of 0 to 5000 ppm B. Later on, experimental models were built in order to study the feasibility of automation. The analysis of boron was finally performed, under the previously established conditions, with an automated system comprising the operations of transport, irradiation and counting. An improvement in the quality of the analysis was observed, with boron concentrations as low as 5 ppm being determined with a precision level better than 0.4%. The experimental model features all basic design elements for an automated device for the analysis of boron in agueous solutions wherever this is required, as in the operation of nuclear reactors. (Author) [pt

Powering up with indirect reciprocity in a large-scale field experiment.

Science.gov (United States)

Yoeli, Erez; Hoffman, Moshe; Rand, David G; Nowak, Martin A

2013-06-18

A defining aspect of human cooperation is the use of sophisticated indirect reciprocity. We observe others, talk about others, and act accordingly. We help those who help others, and we cooperate expecting that others will cooperate in return. Indirect reciprocity is based on reputation, which spreads by communication. A crucial aspect of indirect reciprocity is observability: reputation effects can support cooperation as long as peoples' actions can be observed by others. In evolutionary models of indirect reciprocity, natural selection favors cooperation when observability is sufficiently high. Complimenting this theoretical work are experiments where observability promotes cooperation among small groups playing games in the laboratory. Until now, however, there has been little evidence of observability's power to promote large-scale cooperation in real world settings. Here we provide such evidence using a field study involving 2413 subjects. We collaborated with a utility company to study participation in a program designed to prevent blackouts. We show that observability triples participation in this public goods game. The effect is over four times larger than offering a $25 monetary incentive, the company's previous policy. Furthermore, as predicted by indirect reciprocity, we provide evidence that reputational concerns are driving our observability effect. In sum, we show how indirect reciprocity can be harnessed to increase cooperation in a relevant, real-world public goods game.

Spatial distribution, risk factors and haemato-biochemical alterations associated with Theileria equi infected equids of Punjab (India) diagnosed by indirect ELISA and nested PCR.

Science.gov (United States)

Sumbria, Deepak; Singla, L D; Kumar, Sanjay; Sharma, Amrita; Dahiya, Rajesh K; Setia, Raj

2016-03-01

Equine piroplasmosis is a febrile, tick-borne disease of equids predominately caused by obligatory intra-erythrocytic protozoa Theileria equi in the Indian sub-continent. A cross-sectional study was carried out on 464 equids (426 horses and 38 donkeys/mules) in Punjab, India to assess the level of exposure to equine piroplasmosis by 18S rRNA gene nested polymerase chain reaction (nPCR) and equine merozoite antigen-2 (EMA2) indirect-ELISA (enzyme linked immunosorbent assay), to investigate risk factors and haemato-biochemical alterations associated with the infection. The endemicity of the disease was confirmed by positive PCR amplification in 21.77% and positive antibody titers in 49.78% equid samples. There was a fair agreement between these two diagnostic techniques (Kappa coefficient=0.326). The spatial distribution analysis revealed an increasing trend of T. equi prevalence from north-eastern to south-western region of Punjab by both the techniques correspondingly, which proffered a direct relation with temperature and inverse with humidity variables. The relatively prominent risk factor associated with sero-positivity was the presence of other domestic animals in the herd, while the propensity of finding a positive PCR amplification was higher in donkeys/mules, animal kept at unorganised farm or those used for commercial purposes as compared to their counterparts. There was a significant increase in globulins, gamma glutamyl-transferase, total bilirubin, direct bilirubin, indirect bilirubin, glucose levels and decrease in total erythrocyte count, haemoglobin, packed cell volume by animals, which were revealed positive by nPCR (may or may not positive by indirect-ELISA) and increase in creatinine, total bilirubin, direct bilirubin, glucose and decrease in total erythrocytes count by animals, which were revealed positive by indirect-ELISA (alone). To our knowledge, this study, for the first time, brings out a comprehensive report on the status on spatial

Exploring the nanoworld

International Nuclear Information System (INIS)

Cockayne, D.

2002-01-01

Full text: The nanoworld is a real world waiting to be explored and to be exploited, and the key to this world is microscopy. Modem techniques of microscopy reveal not only atoms and molecules, but also how they combine and interact. They allow us to explore not only the natural but also the synthesised nanoworld. Through this exploration, we can discover new natural forms which can act as templates for constructing novel materials of technological and scientific importance, we can obtain knowledge about the nanoworld (eg the structure of macromolecules) which gives us the means to manipulate the natural world, and we can discover how nature uses microstructure to achieve materials properties (eg strength) which we can then mimic. There are many modern forms of microscopy which are used in this exploration. They include not only a variety of microscopes (eg electron, atomic force, scanning tunnelling) but also an increasing range of sophisticated techniques such as electron tomography, image reconstruction, energy loss spectroscopy and high resolution microscopy, in which mathematical manipulation of the data is playing an increasingly important role. Meanwhile developments in aberration correctors and electron energy monochromation are taking microscopy into a new realm of resolution both in imaging and spectroscopy. Research at the nanoscale is causing a convergence between the biological and physical sciences, largely because the tools and techniques they use are becoming increasingly common to both fields. This challenges us to arrange our activities to optimise our efforts and resources. So we see significant developments in shared instrumentation and remote operation, and we see the setting up of nanotechnology institutes where researchers from across the biological, mathematical, materials and medical disciplines explore together. Copyright (2002) Australian Society for Electron Microscopy Inc

Environmental effects of indirect subsidies

International Nuclear Information System (INIS)

Van Beers, C.P.; De Moor, A.P.G.; Van den Bergh, J.C.J.M.; Oosterhuis, F.H.

2003-01-01

The aim of the study on the title subject is to develop a transparent integrated method to determine and analyze the environmental impacts of indirect subsidies, applied in the sectors agriculture, energy, mobility, and tourism. From the results it appears that the hazardous effects of subsidies are big. Examples are milk, the regulating energy levy, and kerosene [nl

Anesthetic technique for inferior alveolar nerve block: a new approach

Science.gov (United States)

PALTI, Dafna Geller; de ALMEIDA, Cristiane Machado; RODRIGUES, Antonio de Castro; ANDREO, Jesus Carlos; LIMA, José Eduardo Oliveira

2011-01-01

Background Effective pain control in Dentistry may be achieved by local anesthetic techniques. The success of the anesthetic technique in mandibular structures depends on the proximity of the needle tip to the mandibular foramen at the moment of anesthetic injection into the pterygomandibular region. Two techniques are available to reach the inferior alveolar nerve where it enters the mandibular canal, namely indirect and direct; these techniques differ in the number of movements required. Data demonstrate that the indirect technique is considered ineffective in 15% of cases and the direct technique in 1329% of cases. Objective Objective: The aim of this study was to describe an alternative technique for inferior alveolar nerve block using several anatomical points for reference, simplifying the procedure and enabling greater success and a more rapid learning curve. Materials and Methods A total of 193 mandibles (146 with permanent dentition and 47 with primary dentition) from dry skulls were used to establish a relationship between the teeth and the mandibular foramen. By using two wires, the first passing through the mesiobuccal groove and middle point of the mesial slope of the distolingual cusp of the primary second molar or permanent first molar (right side), and the second following the oclusal plane (left side), a line can be achieved whose projection coincides with the left mandibular foramen. Results The obtained data showed correlation in 82.88% of cases using the permanent first molar, and in 93.62% of cases using the primary second molar. Conclusion This method is potentially effective for inferior alveolar nerve block, especially in Pediatric Dentistry. PMID:21437463

Assessing the indirect effects due to natural hazards on a mesoscale

Science.gov (United States)

Pfurtscheller, C.; Schwarze, R.

2009-04-01

Measuring indirect economic costs and other effects from natural hazards, especially floods in alpine and other mountainous regions, are a necessary part of a comprehensive economic assessment. Their omission seriously affects the relative economic benefits of structural or non structural measures of flood defence. Surpassing controversial, IO-model-based economic estimates, analysing indirect economic effects lead to the key question of identifying and evaluating the drivers of indirect economic effects and resilience to system effects in the regional economy, i.e. at the meso-level. This investigation takes place for the catastrophic floods in summer 2005 in the provinces of Tyrol and Vorarlberg, Austria, which caused an estimated € 670 Mio direct loss on private and public assets and severe interruptions in lifeline services. The paper starts out with differentiating the concept of indirect economic costs from direct costs, examing different temporal (short vs. long-term) and spatial (macro-, meso- vs. microeconomic) system boundaries. It surveys common theories of economic resilience and vulnerability at the regional economy level. Indirect effects at the regional economy level can be defined as interferences of the economic exchange of goods and services triggered by breakdowns of transport lines and critical production inputs. The extent and persistence of indirect effects of natural hazards is not only by parameters of the extreme event, such as duration and amplitude of the flood, but much more by resilience parameters of the regional economy such as size of enterprises, the network structure (linkages) of the regional economy, availability of insurance and relief funds, and the stock of inventory. These effects can only be dissected by means of expert judgement and event studies. This paper presents the results of a survey conducted among business practioneers, members of chamber of commerce, civil protection agencies to identify and scale the drivers of

Types of suggestibility: Relationships among compliance, indirect, and direct suggestibility.

Science.gov (United States)

Polczyk, Romuald; Pasek, Tomasz

2006-10-01

It is commonly believed that direct suggestibility, referring to overt influence, and indirect suggestibility, in which the intention to influence is hidden, correlate poorly. This study demonstrates that they are substantially related, provided that they tap similar areas of influence. Test results from 103 students, 55 women and 48 men, were entered into regression analyses. Indirect suggestibility, as measured by the Sensory Suggestibility Scale for Groups, and compliance, measured by the Gudjonsson Compliance Scale, were predictors of direct suggestibility, assessed with the Barber Suggestibility Scale. Spectral analyses showed that indirect suggestibility is more related to difficult tasks on the BSS, but compliance is more related to easy tasks on this scale.

Direct and indirect welfare chauvinism as party strategies

DEFF Research Database (Denmark)

Careja, Romana; Elmelund-Præstekær, Christian; Klitgaard, Michael Baggesen

2016-01-01

welfare chauvinism occurs as a result of legislative changes that explicitly exclude recipients from social protection or reduce the level thereof on the basis of ethnicity. Indirect welfare chauvinism is the result of policy measures that apply to both natives and immigrants, but which deliberately...... and deliberate policy-making strategies of the party. It shows that the distinction between direct and indirect chauvinism is a useful theoretical tool for understanding how the Danish People's Party can fulfill the expectations of both its electorate and its coalition partners, even if they point in different...

Borehole logging for uranium exploration

International Nuclear Information System (INIS)

1982-01-01

The present text has been prepared taking into account the requirements of both developing countries, which might be at an incipient stage of uranium exploration, and industrialized countries, where more advanced exploration and resource evaluation techniques are commonly in use. While it was felt necessary to include some discussion of exploration concepts and fundamental physical principles underlying various logging methods, it was not the intention of the consultants to provide a thorough, detailed explanation of the various techniques, or even to give a comprehensive listing thereof. However, a list of references has been included, and it is strongly recommended that the serious student of mineral logging consult this list for further guidance

Shattered illusions: the effect of explicit memory mediation on an indirect memory test.

Science.gov (United States)

Gooding, P A; Mayes, A R; Meudell, P R

1999-05-01

Four experiments were conducted to explore the possible involvement of explicit memory in an indirect memory test in which white noise accompanying old sentences was judged to be quieter than white noise accompanying new sentences (Jacoby, Allan, Collins & Larwill, 1988). Experiment 1 established that this effect lasted up to 1 week. Experiment 2 found that a group of amnesic patients showed a noise effect that was marginally above chance and not significantly less that that of their matched controls after a delay of one day. Effect of time pressure at test (Experiment 3) and divided attention at study (Experiment 4) suggested that the memory processes mediating the noise effect were not automatic, although the possibility that the processes involve enhanced fluency is also discussed.

Indirect Determination of Chemical Composition and Fuel Characteristics of Solid Waste

DEFF Research Database (Denmark)

Riber, Christian; Christensen, Thomas Højlund

Determination of chemical composition of solid waste can be performed directly or indirectly by analysis of combustion products. The indirect methodology instrumented by a full scale incinerator is the only method that can conclude on elements in trace concentrations. These elements are of great...... interest in evaluating waste management options by for example LCA modeling. A methodology description of indirect determination of chemical composition and fuel properties of waste is provided and validated by examples. Indirect analysis of different waste types shows that the chemical composition...... is significantly dependent on waste type. And the analysis concludes that the transfer of substances in the incinerator is a function of waste chemical content, incinerator technology and waste physical properties. The importance of correct representation of rare items in the waste with high concentrations...

A Computational Approach to the Interpretation of Indirect Speech Acts

NARCIS (Netherlands)

Beun, R.J.; Eijk, R.M. van; Meyer, J-J.Ch.; Vergunst, N.L.

2006-01-01

An Indirect Speech Act (ISA) is an utterance that conveys a message that is different from its literal meaning, often for reasons of politeness or subtlety. The DenK-system provides us with a non-compositional way to look at Indirect Speech Acts that contain modal verbs. We can extract the

Pain and stress assessment after retinopathy of prematurity screening examination: Indirect ophthalmoscopy versus digital retinal imaging

Directory of Open Access Journals (Sweden)

Moral-Pumarega M

2012-08-01

Full Text Available Abstract Background Increasingly, neonatal clinics seek to minimize painful experiences and stress for premature infants. Fundoscopy performed with a binocular indirect ophthalmoscope is the reference examination technique for screening of retinopathy of prematurity (ROP, and it is associated with pain and stress. Wide-field digital retinal imaging is a recent technique that should be evaluated for minimizing infant pain and stress. Methods The purpose of the study was to assess and compare the impact of using a binocular indirect ophthalmoscope (BIO, or wide-field digital retinal imaging (WFDRI on pain and stress in infants undergoing ROP screening examination. This was a comparative evaluation study of two screening procedures. Ophthalmologic examinations (N = 70 were performed on 24 infants with both BIO and WFDRI. Pain assessments were performed with two specific neonatal scales (Crying, requires oxygen, increased vital signs, expression and sleeplessness, CRIES and, Premature infant pain profile, PIPP just prior to the examination, and 30 seconds, 1 hour, and 24 hours later after ending the examination. Results Changes over time were significantly different between BIO and WFDRI with both scales (PIPP score, p = .007, and CRIES score, p = .001. Median PIPP score (interquartile interval at baseline was 4 (3–5. At 30 seconds the score was 8 (6–9 for BIO and 6 (5–7 for WFDRI, respectively. The increase in PIPP score between baseline and 30 seconds was significantly lower with WFDRI (p = .006. The median increase in CRIES score from baseline to 30 seconds was 1 point lower for WFDRI than for BIO (p  Conclusions A transient short-term pain and stress response occurs with both BIO and WFDRI. Infants examined for screening of ROP with digital retinal imaging present less pain and stress at 30 seconds following completion of the exam when compared with binocular indirect ophthalmoscopy.

Frontier areas and exploration techniques. Frontier uranium exploration in the South-Central United States

International Nuclear Information System (INIS)

Campbell, M.D.; Biddle, K.T.

1977-01-01

Selected areas of the South-Central United States outside the known U trends of South Texas have a largely untested potential for the occurrence of significant U mineralization. These areas, underlain by Tertiary and older sediments, include parts of Texas, Oklahoma, Arkansas, Louisiana, Mississippi and Alabama. The commonly accepted criteria employed in U exploration are applicable to these frontier areas but special consideration must also be given to the atypical geologic aspects of such areas as they may apply to relatively unique types of U mineralization or to the development of special exploration criteria for common types of roll-front and fault-and dome-related uranium mineralization. The procedures used in evaluating frontier areas should be based on comprehensive evaluations involving: (1) location and analysis of potential source rocks (e.g., intrusive igneous rocks, bentonitic sediments, unique complexes, etc.); (2) definition of regional variations in the potential host sediments (e.g. marginal marine to nonmarine environments of deposition); (3) review of all available radiometric data in Tertiary or older rocks; (4) local groundwater sampling; (5) widely spaced reconnaissance (or stratigraphic) drilling, coring and borehole geophysical logging to define favorable sedimentary facies and to establish the specific lithologic character of the sediments; and (6) detailed petrographic evaluation of all available samples to define the environment of deposition and diagenetic history of ''favorable'' sediments. If procedures produce favorable results, an expanded exploration program is justified. Depths up to 3,000 feet should be anticipated if up-dip information is favorable. Selected areas are discussed that have: (1) favorable source and host rocks;(2) favorable age; (3) favorable regional and local structure; and (4) radiometric characteristics favorable for U mineralization of potentially economic grade and reserves in the areas

Effect of the phosphor screen optics on the Swank noise performance in indirect-conversion x-ray imaging detectors

International Nuclear Information System (INIS)

Lim, C H; Moon, M-K; Kam, S; Han, J C; Yun, S; Youn, H; Kim, H K; Jeon, H

2014-01-01

The optics between the scintillators and photodiode arrays of indirect-conversion x-ray imaging systems requires careful design because it can be a cause of secondary quantum sink, which reduces the detective quantum efficiency at high spatial frequencies. The aim of this study was the investigation of the effect of the optical properties of granular phosphor screens — including optical coupling materials and passivation layers in photodiode arrays — on the imaging performance of indirect-conversion x-ray imaging detectors using the Monte Carlo technique. In the Monte Carlo simulations, various design parameters were considered, such as the refractive index of the optical coupler and the passivation layer, the reflection coefficient at the screen backing, and the thickness of the optical coupler. We developed a model that describes the optical pulse-height distributions based on the depth-dependent collection efficiency obtained from the simulations. We used the model to calculate the optical Swank noise. A loss in the number of collected optical photons was inevitable owing to the introduction of intermediate optics and mismatches in the optical design parameters. However, the collection efficiency marginally affected the optical Swank factor performance. The results and methodology of this study will facilitate better designs and optimization of indirect-conversion x-ray detectors

46 CFR 154.1720 - Indirect refrigeration.

Science.gov (United States)

2010-10-01

... Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Special Design and Operating Requirements § 154.1720 Indirect refrigeration. A refrigeration system that is used to cool acetaldehyde, ethylene...

Lack of indirect sensitization in vivo

International Nuclear Information System (INIS)

Hetzel, F.W.; Avery, K.; Mensinger, M.; Frinak, S.; Tidwell, C.

1985-01-01

The possible utility of respiratory inhibiting drugs as indirect radiation sensitizers has been investigated in both in vitro and in vivo systems. In vitro studies were conducted in V79 monolayer and spheroid cultures examining both respiratory inhibition and radiation survival as end points. These drugs (BCNU, Mustargen and Chlorambucil) were found to be potent respiratory inhibitors and, in the spheroid system, to be effective indirect radiation sensitizers with enhancement ratios of approximately 2.0. In vivo studies with these drugs have also been conducted in a C/sub 3/H mouse MCa tumor system to determine if the same reoxygenation effect observed in spheroids could be demonstrated in the solid tumor system. Detailed microelectrode studies, employing each drug at its LD/sub 10/ level, have been unable to demonstrate any drug induced reoxygenation for any of the drugs tested. Complete details are presented

An improved recommendation algorithm via weakening indirect linkage effect

Science.gov (United States)

Chen, Guang; Qiu, Tian; Shen, Xiao-Quan

2015-07-01

We propose an indirect-link-weakened mass diffusion method (IMD), by considering the indirect linkage and the source object heterogeneity effect in the mass diffusion (MD) recommendation method. Experimental results on the MovieLens, Netflix, and RYM datasets show that, the IMD method greatly improves both the recommendation accuracy and diversity, compared with a heterogeneity-weakened MD method (HMD), which only considers the source object heterogeneity. Moreover, the recommendation accuracy of the cold objects is also better elevated in the IMD than the HMD method. It suggests that eliminating the redundancy induced by the indirect linkages could have a prominent effect on the recommendation efficiency in the MD method. Project supported by the National Natural Science Foundation of China (Grant No. 11175079) and the Young Scientist Training Project of Jiangxi Province, China (Grant No. 20133BCB23017).

Indirect control of flexible demand for power system applications

DEFF Research Database (Denmark)

Sossan, Fabrizio

This thesis addresses the topic of control of flexible demand to provide support to the operation of the electric power system. We focus on the indirect control approach, a framework that enables demand response by means of a consumption incentive signal. Initially, the concept of flexibility...... a shift in the consumption according to an indirect control signal. We present from simple control algorithms with a few requirements up to model predictive control strategies. The performance of the indirect control algorithms are compared by means of hardware-in-the-loop simulations using Power...... and storage in the operation of the future power system, we develop a model predictive control strategy for a smart building with the objective of supplying iii space heating and providing regulating power to the grid according to a dynamic electricity price. We named this application energy replacement...

Stability Concerns for Indirect Consumer Control in Smart Grids

DEFF Research Database (Denmark)

Juelsgaard, Morten; Andersen, Palle; Wisniewski, Rafal

2013-01-01

by an external third party, and indirect consumer control through incentives and price signals. In this work we present a simple formulation of indirect control, where the behavior of each consumer, is governed by local optimization of energy consumption. The local optimization accounts for both cost of energy...... and distribution losses, as well as any discomfort incurred by consumers from any shift in energy consumption. Our work will illustrate that in the simplest formulation of indirect control, the stability is greatly affected of both the behavior of consumers, and the number of consumers to include. We will show how......Demand side management will be an important tool for maintaining a balanced electrical grid in the future, when the penetration of volatile resources, such as wind and solar energy increases. Recent research focuses on two different management approaches, namely direct consumer control...

Indirect Detection Analysis: Wino Dark Matter Case Study

Energy Technology Data Exchange (ETDEWEB)

Hryczuk, Andrzej [Munich, Tech. U.; Cholis, Ilias [Fermilab; Iengo, Roberto [SISSA, Trieste; Tavakoli, Maryam [IPM, Tehran; Ullio, Piero [INFN, Trieste

2014-07-15

We perform a multichannel analysis of the indirect signals for the Wino Dark Matter, including one-loop electroweak and Sommerfeld enhancement corrections. We derive limits from cosmic ray antiprotons and positrons, from continuum galactic and extragalactic diffuse γ-ray spectra, from the absence of γ-ray line features at the galactic center above 500 GeV in energy, from γ-rays toward nearby dwarf spheroidal galaxies and galaxy clusters, and from CMB power-spectra. Additionally, we show the future prospects for neutrino observations toward the inner Galaxy and from antideuteron searches. For each of these indirect detection probes we include and discuss the relevance of the most important astrophysical uncertainties that can impact the strength of the derived limits. We find that the Wino as a dark matter candidate is excluded in the mass range bellow simeq 800 GeV from antiprotons and between 1.8 and 3.5 TeV from the absence of a γ-ray line feature toward the galactic center. Limits from other indirect detection probes confirm the main bulk of the excluded mass ranges.

Indirect-fired gas turbine bottomed with fuel cell

Science.gov (United States)

Micheli, P.L.; Williams, M.C.; Parsons, E.L.

1995-09-12

An indirect-heated gas turbine cycle is bottomed with a fuel cell cycle with the heated air discharged from the gas turbine being directly utilized at the cathode of the fuel cell for the electricity-producing electrochemical reaction occurring within the fuel cell. The hot cathode recycle gases provide a substantial portion of the heat required for the indirect heating of the compressed air used in the gas turbine cycle. A separate combustor provides the balance of the heat needed for the indirect heating of the compressed air used in the gas turbine cycle. Hot gases from the fuel cell are used in the combustor to reduce both the fuel requirements of the combustor and the NOx emissions therefrom. Residual heat remaining in the air-heating gases after completing the heating thereof is used in a steam turbine cycle or in an absorption refrigeration cycle. Some of the hot gases from the cathode can be diverted from the air-heating function and used in the absorption refrigeration cycle or in the steam cycle for steam generating purposes. 1 fig.

Indirect methods in nuclear astrophysics

International Nuclear Information System (INIS)

Bertulani, C.A.; Shubhchintak; Mukhamedzhanov, A.; Kadyrov, A. S.; Kruppa, A.; Pang, D. Y.

2016-01-01

We discuss recent developments in indirect methods used in nuclear astrophysics to determine the capture cross sections and subsequent rates of various stellar burning processes, when it is difficult to perform the corresponding direct measurements. We discuss in brief, the basic concepts of Asymptotic Normalization Coefficients, the Trojan Horse Method, the Coulomb Dissociation Method, (d,p), and charge-exchange reactions. (paper)

Endometrioid endometrial carcinoma indirectly caused by pituitary prolactinoma: a case report.

Science.gov (United States)

Nishino, Kimihiro; Niwa, Yuri; Mizutani, Teruyuki; Shimizu, Ken; Hayashi, Kazumasa; Chaya, Jyunya; Kato, Noriko; Yamamuro, Osamu

2013-01-01

We present the case of a 44-year-old nulliparous woman who experienced irregular menstrual cycles for about 10 years and developed both pituitary prolactinoma and endometrioid endometrial carcinoma. In premenopausal women, hyperprolactinemia causes hypogonadism by inhibiting secretion of gonadotropin-releasing hormone and thus suppressing luteinizing hormone levels, which can cause menstrual disorders ranging from amenorrhea, oligomenorrhea and chronic anovulatory cycle to short luteal phase of the menstrual cycle. A chronic anovulatory menstrual cycle is the most common cause of long-term exposure of the endometrium to endogenous estrogen without adequate opposition from progestins, which can lead to endometrioid endometrial carcinoma. In this case, pituitary prolactinoma may have caused the chronic anovulatory cycle and indirectly led to the endometrioid endometrial carcinoma. In patients for whom the cause of irregular menstruation and chronic anovulatory cycle is suspected to be hyperprolactinemia, explorations of both the hypophysis and endometrium are essential.

Endometrioid Endometrial Carcinoma Indirectly Caused by Pituitary Prolactinoma:A Case Report

Directory of Open Access Journals (Sweden)

Kimihiro Nishino

2013-01-01

Full Text Available We present the case of a 44-year-old nulliparous woman who experienced irregular menstrual cycles for about 10 years and developed both pituitary prolactinoma and endometrioid endometrial carcinoma. In premenopausal women, hyperprolactinemia causes hypogonadism by inhibiting secretion of gonadotropin-releasing hormone and thus suppressing luteinizing hormone levels, which can cause menstrual disorders ranging from amenorrhea, oligomenorrhea and chronic anovulatory cycle to short luteal phase of the menstrual cycle. A chronic anovulatory menstrual cycle is the most common cause of long-term exposure of the endometrium to endogenous estrogen without adequate opposition from progestins, which can lead to endometrioid endometrial carcinoma. In this case, pituitary prolactinoma may have caused the chronic anovulatory cycle and indirectly led to the endometrioid endometrial carcinoma. In patients for whom the cause of irregular menstruation and chronic anovulatory cycle is suspected to be hyperprolactinemia, explorations of both the hypophysis and endometrium are essential.

COATING AND MANDREL EFFECTS ON FABRICATION OF GLOW DISCHARGE POLYMER NIF SCALE INDIRECT DRIVE CAPSULES

International Nuclear Information System (INIS)

NIKROO, A.; PONTELANDOLFO, J.M.; CASTILLO, E.R.

2002-01-01

OAK A271 COATING AND MANDREL EFFECTS ON FABRICATION OF GLOW DISCHARGE POLYMER NIF SCALE INDIRECT DRIVE CAPSULES. Targets for the National Ignition Facility (NIF) need to be about 200 (micro)m thick and 2 mm in diameter. These dimensions are well beyond those currently fabricated on a routine basis. They have investigated fabrication of near NIF scale targets using the depolymerizable mandrel technique. Poly-alpha-methylstyrene (PAMS) mandrels, about 2 mm in diameter, of varying qualities were coated with as much as 125 (micro)m of glow discharge polymer (GDP). The surface finish of the final shells was examined using a variety of techniques. A clear dependence of the modal spectrum of final GDP shell on the quality of the initial PAMS mandrels was observed. isolated features were found to be the greatest cause for a shell not meeting the NIF standard

L'indirection : Procédé d'expression et de persuasion en communication publique

Directory of Open Access Journals (Sweden)

Gilles Gauthier

2001-12-01

Full Text Available Abstract The article is about the indirection process presented in Searle's and Vanderveken's theory of speech acts: the performance of a primary speech act by means of the accomplishment of a secondary speech act. Considering the typology of speech acts and their performance conditions, the article first proposes an explicit definition of indirection. Following from this definition, several mechanisms for indirection are identified, i.e. different ways of performing an indirect speech act. The article then discusses the indirection mechanisms used in advertising (five mechanisms and in political communication (six mechanisms. Finally, a number of reasons are given to explain the relative importance of the use of indirection in these two fields of public communication according to their persuasive goal.

Remote sensing in uranium exploration. Basic guidance

International Nuclear Information System (INIS)

1981-01-01

The purpose of this publication is to provide the reader with a basis for making an intelligent approach to the use of remote sensing in uranium exploration. It includes: A description of the various techniques; specific applications in view of exploration strategy and selection of appropriate techniques, and some examples of applications; availability and costs; a bibliography

Remote sensing in uranium exploration. Basic guidance

Energy Technology Data Exchange (ETDEWEB)

1981-01-01

The purpose of this publication is to provide the reader with a basis for making an intelligent approach to the use of remote sensing in uranium exploration. It includes: A description of the various techniques; specific applications in view of exploration strategy and selection of appropriate techniques, and some examples of applications; availability and costs; a bibliography.

Indirect sensorless speed control of a PMSG for wind application

DEFF Research Database (Denmark)

Diaz, S.A.; Silva, C.; Juliet, J.

2009-01-01

the method usually referred in the literature as indirect speed control (ISC). The principle of this method is the regulation of the generator torque as function of rotor speed such that the steady state operation is at the MPPT. This strategy normally requires the knowledge of the shaft speed to determinate...... in the whole wind generator system a sensorless scheme is proposed, thereby avoiding problems of electromagnetic interferences and failures in the position sensor. Usually, in wind drive system, the generator is not operated a very low speeds, therefore problems related to low back-emf for flux estimation...... the reference torque and rotor position for the orientation of the vector torque control of the PMSG. To achieve both, speed and position estimation, the sensorless technique based in back-emf estimation is proposed. Also in this paper, a laboratory set-up is described. The experimental bench is composed...

Direct and Indirect Effects of PM on the Cardiovascular System

Science.gov (United States)

Nelin, Timothy D.; Joseph, Allan M.; Gorr, Matthew W.; Wold, Loren E.

2011-01-01

Human exposure to particulate matter (PM) elicits a variety of responses on the cardiovascular system through both direct and indirect pathways. Indirect effects of PM on the cardiovascular system are mediated through the autonomic nervous system, which controls heart rate variability, and inflammatory responses, which augment acute cardiovascular events and atherosclerosis. Recent research demonstrates that PM also affects the cardiovascular system directly by entry into the systemic circulation. This process causes myocardial dysfunction through mechanisms of reactive oxygen species production, calcium ion interference, and vascular dysfunction. In this review, we will present key evidence in both the direct and indirect pathways, suggest clinical applications of the current literature, and recommend directions for future research. PMID:22119171

27 CFR 6.32 - Indirect interest.

Science.gov (United States)

2010-04-01

... OF THE TREASURY LIQUORS âTIED-HOUSEâ Unlawful Inducements Interest in Retail Property § 6.32 Indirect interest. Industry member interest in retail property includes any interest acquired by corporate officials, partners, employees or other representatives of the industry member. Any interest in retail property...

Indirect N2O emission due to atmospheric N deposition for the Netherlands

International Nuclear Information System (INIS)

Denier van der Gon, H.; Bleeker, A.

2005-10-01

Nitrous oxide (N2O) is a potent greenhouse gas produced in soils and aquatic systems. The UNFCCC requires participants to report 'indirect' N2O emissions, following from agricultural N losses to ground- and surface water and N deposition on (other) ecosystems due to agricultural sources. Indirect N2O emission due to atmospheric N deposition is presently not reported by the Netherlands. In this paper, we quantify the consequences of various tiers to estimate indirect N2O due to deposition for a country with a high agricultural N use and discuss the reliability and potential errors in the IPCC methodology. A literature review suggests that the current IPCC default emission factor for indirect N2O from N deposition is underestimated by a factor 2. Moreover, considering anthropogenic N emissions from agriculture only and not from e.g., traffic and industry, results in further underestimation of indirect N2O emissions. We calculated indirect N2O emissions due to Dutch anthropogenic N emissions to air by using official Dutch N emission data as input in an atmospheric transport and deposition model in combination with land use databases. Next, land use-specific emission factors were used to estimate the indirect N2O emission. This revealed that (1) for some countries, like the Netherlands, most agricultural N emitted will be deposited on agricultural soils, not on natural ecosystems and, (2) indirect N2O emissions are at least 20% higher because more specific emission factors can be applied that are higher than the IPCC default. The results suggest that indirect N2O emission due to deposition is underestimated in current N2O budgets

The indirect costs of ankylosing spondylitis: a systematic review and meta-analysis.

Science.gov (United States)

Malinowski, Krzysztof Piotr; Kawalec, Paweł

2015-04-01

The aim of this systematic review was to collect and summarize all current data on the indirect costs related to absenteeism and presenteeism associated with ankylosing spondylitis. The search was conducted using Medline, Embase and Centre for Reviews and Dissemination databases. All collected costs were recalculated to average annual cost per patient, expressed in 2013 prices USD using the consumer price index and purchasing power parity. Identified studies were then analyzed to assess their possible inclusion in the meta-analysis. We identified 32 records. The average annual indirect cost per patient varies among all the identified results from US$660.95 to 45,953.87. The mean annual indirect per patient equals US$6454.76. This systematic review summarizes current data related to indirect costs generated by ankylosing spondylitis; it revealed the great economic burden of the disease for society. We observed a great variety of the considered components of indirect costs and their definitions.

A comparative investigation of seven indirect attitude measures.

Science.gov (United States)

Bar-Anan, Yoav; Nosek, Brian A

2014-09-01

We compared the psychometric qualities of seven indirect attitude measures across three attitude domains (race, politics, and self-esteem) with a large sample (N = 23,413). We compared the measures on internal consistency, sensitivity to known effects, relationships with indirect and direct measures of the same topic, the reliability and validity of single-category attitude measurement, their ability to detect meaningful variance among people with nonextreme attitudes, and their robustness to the exclusion of misbehaving or well-behaving participants. All seven indirect measures correlated with each other and with direct measures of the same topic. These relations were always weak for self-esteem, moderate for race, and strong for politics. This pattern suggests that some of the sources of variation in the reliability and predictive validity of the indirect measures is a function of the concepts rather than the methods. The Implicit Association Test (IAT) and Brief IAT (BIAT) showed the best overall psychometric quality, followed by the Go–No-Go association task, Single-Target IAT (ST-IAT), Affective Misattribution Procedure (AMP), Sorting Paired Features task, and Evaluative Priming. The AMP showed a steep decline in its psychometric qualities when people with extreme attitude scores were removed. Single-category attitude scores computed for the IAT and BIAT showed good relationships with other attitude measures but no evidence of discriminant validity between paired categories. The other measures, especially the AMP and ST-IAT, showed better evidence for discriminant validity. These results inform us on the validity of the measures as attitude assessments, but do not speak to the implicitness of the measured constructs.

The potential indirect effects among plants via shared hummingbird pollinators are structured by phenotypic similarity.

Science.gov (United States)

Bergamo, Pedro Joaquim; Wolowski, Marina; Maruyama, Pietro Kiyoshi; Vizentin-Bugoni, Jeferson; Carvalheiro, Luísa G; Sazima, Marlies

2017-07-01

Plant species within communities may overlap in pollinators' use and influence visitation patterns of shared pollinators, potentially engaging in indirect interactions (e.g., facilitation or competition). While several studies have explored the mechanisms regulating insect-pollination networks, there is a lack of studies on bird-pollination systems, particularly in species-rich tropical areas. Here, we evaluated if phenotypic similarity, resource availability (floral abundance), evolutionary relatedness and flowering phenology affect the potential for indirect effects via shared pollinators in hummingbird-pollinated plant species within four communities in the Brazilian Atlantic forest. Among the evaluated factors, phenotypic similarity (corolla length and anther height) was the most important variable, while resource availability (floral abundance) had a secondary importance. On the other hand, evolutionary relatedness and flowering phenology were less important, which altogether highlights the relevance of convergent evolution and that the contribution of a plant to the diet of the pollinators of another plant is independent of the level of temporal overlap in flowering in this tropical system. Interestingly, our findings contrast with results from multiple insect-pollinated plant communities, mostly from temperate regions, in which floral abundance was the most important driver, followed by evolutionary relatedness and phenotypic similarity. We propose that these contrasting results are due to high level of specialization inherent to tropical hummingbird-pollination systems. Moreover, our results demonstrated that factors defining linkage rules of plant-hummingbird networks also determinate plant-plant potential indirect effects. Future studies are needed to test if these findings can be generalized to other highly specialized systems. Overall, our results have important implications for the understanding of ecological processes due resource sharing in

Research on geochemical exploration in geotherm development

International Nuclear Information System (INIS)

Hirowatari, Kazuo; Imaizumi, Yukio; Koga, Akito; Iwanaga, Tatsuto.

1987-01-01

The decisive factor of geotherm development is to improve the exploration techniques. By effectively carrying out the selection of promising development spots and the decision of well drilling positions, the geotherm development exceeding existing energy sources becomes feasible. There have been many problems in conventional geotherm exploration such as the high cost and long work period, therefore, it was decided to advance the research on geochemical exploration techniques which are relatively simple and can be carried out with low cost. When the techniques of geochemistry are used, for example, in the case that there are hot springs or fumaroles, the temperature, origin, properties and so on of underground hot water reservoirs can be estimated from their chemical composition. The method of examining the mercury concentration in soil and soil air has been in practical use in the geothermal districts where the ground surface symptom lacks. This time, the method of investigation using radon, thoron and gamma ray as the exploration indices was newly studied. The index compositions for geochemical exploration, new exploration index compositions, the method of measurement, the basic investigation and on-the-spot investigation are reported. (Kako, I.)

A comparative study of direct and indirect solar drying of mango ...

African Journals Online (AJOL)

A comparative study of direct and indirect solar drying of mango. ... Thus, indirect solar dryer was found to be suitable for industrial or semi industrial mango drying, whereas direct solar dryer was appropriate to a family ... HOW TO USE AJOL.

Posttraumatic Stress Disorder and Suicidal Behavior: Indirect Effects of Impaired Social Functioning.

Science.gov (United States)

Dutton, Courtney E; Rojas, Sasha M; Badour, Christal L; Wanklyn, Sonya G; Feldner, Matthew T

2016-01-01

Social functioning is negatively impacted by the presence of PTSD, while increasing risk of suicidal behavior among individuals with PTSD. However, little research has examined the specific role of social functioning in the association between PTSD and suicidal behavior. Parallel multiple indirect effects analyses were performed to understand the unique indirect effects of four aspects of social functioning. Indirect effects of PTSD on suicidal ideation were significant through three pathways: interpersonal conflict, perceived family support, and interpersonal apprehension. Perceived family support was the only indirect pathway significantly associated with suicide attempt. Findings suggest that social functioning should be assessed and potentially targeted during treatment to help modify the risk for suicidal behavior among individuals with PTSD.

Indirect costs of rheumatoid arthritis

Directory of Open Access Journals (Sweden)

Filip Raciborski

2015-12-01

Full Text Available It is estimated that in Poland about 400,000 persons in general suffer from inflammatory joint diseases, including rheumatoid arthritis (RA. Epidemiological surveys documenting the frequency and disturbance of musculoskeletal disorders in the Polish population are few in number. Most of the estimations are based on epidemiological data from other countries (prevalence of 0.5–1%. According to the data of the National Health Fund in Poland 135,000–157,000 persons in total are treated because of rheumatoid arthritis per year [ICD10 (International Statistical Classification of Diseases and Related Health Problems: M05, M06]. In the case of this group of diseases indirect costs significantly outweigh the direct costs. Indirect costs increase together with activity level of the disease. The cost analysis of productivity loss of RA patients indicates that sickness absenteeism and informal care are the most burdensome. At the national level it amounts in total from 1.2 billion to 2.8 billion PLN per year, depending on the method of analysis. These costs could be significantly reduced through early diagnosis and introduction of effective treatment.

Direct and indirect two-photon processes in semiconductors

International Nuclear Information System (INIS)

Hassan, A.R.

1986-07-01

The expressions describing direct and indirect two-photon absorption in crystals are given. They are valid both near and far from the energy gap. A perturbative approach through two different band models is adopted. The effects of the non-parabolicity and the degeneracy of the energy bands are considered. The numerical results are compared with the other theories and with a recent experimental data in Zn and AgCl. It is shown that the dominant transition mechanisms are of the allowed-allowed type near and far from the gap for both direct and indirect processes. (author)

THE POSITION OF INDIRECT EVIDENCE AS VERIFICATION TOOLS IN THE CARTEL CASE

Directory of Open Access Journals (Sweden)

Veri Antoni

2014-06-01

Full Text Available Indirect (circumstantial evidence, either economic evidence or communication evidence, has been used in cartel cases in many countries such as United States of America, Japan, Australia, Brazil, Malaysia, and others. According to Indonesia criminal procedure law, the position of indirect (circumstantial evidence is categorized as an indication (clue evidence whereas according to Indonesia civil procedure law, indirect (circumstantial evidence is categorized as presumption. Considering the characteristics the antimonopoly law which aims to find material truth, the position of indirect evidence is more properly said to be an indication. Owing to its status as an indication, indirect evidence should be exhibited together with the other direct evidence.   Indirect evidenceatau bukti tidak langsung, baik bukti ekonomi atau bukti komunikasi, telah digunakan dalam kasus-kasus kartel di banyak negara, seperti Amerika Serikat, Jepang, Australia, Brazil, Malaysia, dan lain-lain. Menurut hukum acara pidana Indonesia, posisi bukti tidak langsung dikategorikan sebagai indikasi (bukti petunjuk, padahal menurut hukum acara perdata Indonesia, bukti tidak langsung dikategorikan sebagai praduga. Mengingat karakteristik hukum anti-monopoli yang bertujuan untuk mencari kebenaran materiil, posisi bukti tidak langsung lebih tepat dikatakan indikasi. Karena statusnya sebagai indikasi, bukti tidak langsung harus dipamerkan bersama dengan bukti langsung lainnya.

Direct and indirect effects of attention and visual function on gait impairment in Parkinson's disease: influence of task and turning.

Science.gov (United States)

Stuart, Samuel; Galna, Brook; Delicato, Louise S; Lord, Sue; Rochester, Lynn

2017-07-01

Gait impairment is a core feature of Parkinson's disease (PD) which has been linked to cognitive and visual deficits, but interactions between these features are poorly understood. Monitoring saccades allows investigation of real-time cognitive and visual processes and their impact on gait when walking. This study explored: (i) saccade frequency when walking under different attentional manipulations of turning and dual-task; and (ii) direct and indirect relationships between saccades, gait impairment, vision and attention. Saccade frequency (number of fast eye movements per-second) was measured during gait in 60 PD and 40 age-matched control participants using a mobile eye-tracker. Saccade frequency was significantly reduced in PD compared to controls during all conditions. However, saccade frequency increased with a turn and decreased under dual-task for both groups. Poorer attention directly related to saccade frequency, visual function and gait impairment in PD, but not controls. Saccade frequency did not directly relate to gait in PD, but did in controls. Instead, saccade frequency and visual function deficit indirectly impacted gait impairment in PD, which was underpinned by their relationship with attention. In conclusion, our results suggest a vital role for attention with direct and indirect influences on gait impairment in PD. Attention directly impacted saccade frequency, visual function and gait impairment in PD, with connotations for falls. It also underpinned indirect impact of visual and saccadic impairment on gait. Attention therefore represents a key therapeutic target that should be considered in future research. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

Direct and indirect effects of screening for Chlamydia trachomatis on the prevention of pelvic inflammatory disease: a mathematical modeling study.

Science.gov (United States)

Herzog, Sereina A; Heijne, Janneke C M; Scott, Pippa; Althaus, Christian L; Low, Nicola

2013-11-01

Pelvic inflammatory disease (PID) results from the ascending spread of microorganisms, including Chlamydia trachomatis, to the upper genital tract. Screening could improve outcomes by identifying and treating chlamydial infections before they progress to PID (direct effect) or by reducing chlamydia transmission (indirect effect). We developed a compartmental model that represents a hypothetical heterosexual population and explicitly incorporates progression from chlamydia to clinical PID. Chlamydia screening was introduced, with coverage increasing each year for 10 years. We estimated the separate contributions of the direct and indirect effects of screening on PID cases prevented per 100,000 women. We explored the influence of varying the time point at which clinical PID could occur and of increasing the risk of PID after repeated chlamydial infections. The probability of PID at baseline was 3.1% by age 25 years. After 5 years, the intervention scenario had prevented 187 PID cases per 100,000 women and after 10 years 956 PID cases per 100,000 women. At the start of screening, most PID cases were prevented by the direct effect. The indirect effect produced a small net increase in PID cases, which was outweighed by the effect of reduced chlamydia transmission after 2.2 years. The later that progression to PID occurs, the greater the contribution of the direct effect. Increasing the risk of PID with repeated chlamydial infection increases the number of PID cases prevented by screening. This study shows the separate roles of direct and indirect PID prevention and potential harms, which cannot be demonstrated in observational studies.

27 CFR 6.26 - Indirect interest.

Science.gov (United States)

2010-04-01

... OF THE TREASURY LIQUORS âTIED-HOUSEâ Unlawful Inducements Interest in Retail License § 6.26 Indirect interest. Industry member interest in retail licenses includes any interest acquired by corporate officials, partners, employees or other representatives of the industry member. Any interest in a retail license...

48 CFR 31.203 - Indirect costs.

Science.gov (United States)

2010-10-01

... fiscal year used for financial reporting purposes in accordance with generally accepted accounting... contract or other work, indirect costs are those remaining to be allocated to intermediate or two or more... basis of the benefits accruing to intermediate and final cost objectives. When substantially the same...

Popularity and Resource Control Goals as Predictors of Adolescent Indirect Aggression.

Science.gov (United States)

Dyches, Karmon D; Mayeux, Lara

2015-01-01

Resource Control Theory conceptualizes aggression as a behavior that allows access to, and control of, limited resources (P. H. Hawley, 1999 ). This study investigated the associations of adolescents' indirect aggression with their resource control goals, or goals related to controlling social resources such as dating opportunities and peer status, and with their levels of popularity and social intelligence. Participants were 109 seventh-graders (52% girls) who completed a resource control goals measure, the Tromsø Social Intelligence Scale, and peer nominations of popularity and indirect aggression. Results indicated positive associations between resource control goals and peer-nominated indirect aggression, with popularity further moderating these associations. These findings suggest that the resource control goals of adolescents can be a motivating force to engage in hurtful behaviors. They provide a context from which peer relations researchers can improve their understanding and prevention of adolescents' indirect aggression.

Indirect reciprocity can overcome free-rider problems on costly moral assessment.

Science.gov (United States)

Sasaki, Tatsuya; Okada, Isamu; Nakai, Yutaka

2016-07-01

Indirect reciprocity is one of the major mechanisms of the evolution of cooperation. Because constant monitoring and accurate evaluation in moral assessments tend to be costly, indirect reciprocity can be exploited by cost evaders. A recent study crucially showed that a cooperative state achieved by indirect reciprocators is easily destabilized by cost evaders in the case with no supportive mechanism. Here, we present a simple and widely applicable solution that considers pre-assessment of cost evaders. In the pre-assessment, those who fail to pay for costly assessment systems are assigned a nasty image that leads to them being rejected by discriminators. We demonstrate that considering the pre-assessment can crucially stabilize reciprocal cooperation for a broad range of indirect reciprocity models. In particular for the most leading social norms, we analyse the conditions under which a prosocial state becomes locally stable. © 2016 The Authors.

Economic impact of indirects effects of tourism on the South Bohemian production

OpenAIRE

Michaela Antoušková

2010-01-01

Tourism is characterized as a sector of economy with high multiplier effect; tourism significantly influences other sectors of national economy. Through the multiplier the indirect effect of tourism might be measured. The value of tourist multiplier is a strongly discussed topic, especially in the Czech Republic. The indirect effects of tourism are commonly measured by multiplier in other countries. The article aims to quantify the indirect effects of tourism in the Southern Bohemia. To quant...

Fundamentals - state of the art of radiation techniques

International Nuclear Information System (INIS)

Wogman, N.A.

1982-01-01

In minerals exploration and extraction, nuclear techniques have several advantages. The techniques are elementally specific and their exploration range varies from a few millimeters in average rock formations to more than a meter. Because of the heterogeneous disposition of minerals and difficult environments in which measurements are required (in boreholes, on conveyor belts, in bunkers), interrogating techniques are required which exhibit both elemental specificity and range. It is for these fundamental reasons that nuclear techniques are the only possible techniques which satisfy all requirements. A variety of techniques have been developed and used. These are based on energy dispersive x-ray fluorescence (EDXRF), measurement of natural gamma-ray radiation, gamma-ray attenuation and scattering, and on neutron interactions. This paper discusses the fundamentals of these four techniques and their applications. A table is also provided listing some existing selected applications of nuclear techniques in mineral exploration, mining and processing

Antimony contamination, consequences and removal techniques: A review.

Science.gov (United States)

Li, Jiayu; Zheng, BoHong; He, Yangzhuo; Zhou, Yaoyu; Chen, Xiao; Ruan, Shan; Yang, Yuan; Dai, Chunhao; Tang, Lin

2018-07-30

A significant amount of antimony (Sb) enters into the environment every year because of the wide use of Sb compounds in industry and agriculture. The exposure to Sb, either direct consumption of Sb or indirectly, may be fatal to the human health because both antimony and antimonide are toxic. Firstly, the introduction of Sb chemistry, distribution and health threats are presented in this review, which is essential to the removal techniques. Then, we provide the recent and common techniques to remove Sb, including adsorption, coagulation/flocculation, membrane separation, electrochemical methods, ion exchange and extraction. Removal techniques concentrate on the advantages, drawbacks, economical efficiency and the recent achievements of each technique. We also take an overall consideration of experimental conditions, comparison criteria, and economic aspects. Copyright © 2018 Elsevier Inc. All rights reserved.

Indirect Positive Evidence in the Acquisition of a Subset Grammar

Science.gov (United States)

Schwartz, Misha; Goad, Heather

2017-01-01

This article proposes that second language learners can use indirect positive evidence (IPE) to acquire a phonological grammar that is a subset of their L1 grammar. IPE is evidence from errors in the learner's L1 made by native speakers of the learner's L2. It has been assumed that subset grammars may be acquired using direct or indirect negative…

Anesthetic technique for inferior alveolar nerve block: a new approach

Directory of Open Access Journals (Sweden)

Dafna Geller Palti

2011-02-01

Full Text Available BACKGROUND: Effective pain control in Dentistry may be achieved by local anesthetic techniques. The success of the anesthetic technique in mandibular structures depends on the proximity of the needle tip to the mandibular foramen at the moment of anesthetic injection into the pterygomandibular region. Two techniques are available to reach the inferior alveolar nerve where it enters the mandibular canal, namely indirect and direct; these techniques differ in the number of movements required. Data demonstrate that the indirect technique is considered ineffective in 15% of cases and the direct technique in 13-29% of cases. OBJECTIVE: The aim of this study was to describe an alternative technique for inferior alveolar nerve block using several anatomical points for reference, simplifying the procedure and enabling greater success and a more rapid learning curve. MATERIAL AND METHODS: A total of 193 mandibles (146 with permanent dentition and 47 with primary dentition from dry skulls were used to establish a relationship between the teeth and the mandibular foramen. By using two wires, the first passing through the mesiobuccal groove and middle point of the mesial slope of the distolingual cusp of the primary second molar or permanent first molar (right side, and the second following the oclusal plane (left side, a line can be achieved whose projection coincides with the left mandibular foramen. RESULTS: The obtained data showed correlation in 82.88% of cases using the permanent first molar, and in 93.62% of cases using the primary second molar. CONCLUSION: This method is potentially effective for inferior alveolar nerve block, especially in Pediatric Dentistry.

21 CFR 174.5 - General provisions applicable to indirect food additives.

Science.gov (United States)

2010-04-01

... additives. 174.5 Section 174.5 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) INDIRECT FOOD ADDITIVES: GENERAL § 174.5 General provisions applicable to indirect food additives. (a) Regulations prescribing conditions under...

Engineering and Narrative: Literary Prerequisites as Indirect Communication for Technical Writing

Science.gov (United States)

Jeyaraj, Joseph

2014-01-01

While Engineering values direct communication, indirect communication produces a kind of literacy salient for engineers that direct communication may not offer in the way indirect communication does. This article emphasizes the inadequacies of overly emphasizing direct communication for Engineering majors and explains how teaching indirect…

Trait- and density-mediated indirect interactions initiated by an exotic invasive plant autogenic ecosystem engineer

Science.gov (United States)

Dean E. Pearson

2010-01-01

Indirect interactions are important for structuring ecological systems. However, research on indirect effects has been heavily biased toward top-down trophic interactions, and less is known about other indirect-interaction pathways. As autogenic ecosystem engineers, plants can serve as initiators of nontrophic indirect interactions that, like top-down pathways, can...

Scene independent real-time indirect illumination

DEFF Research Database (Denmark)

Frisvad, Jeppe Revall; Christensen, Niels Jørgen; Falster, Peter

2005-01-01

A novel method for real-time simulation of indirect illumination is presented in this paper. The method, which we call Direct Radiance Mapping (DRM), is based on basal radiance calculations and does not impose any restrictions on scene geometry or dynamics. This makes the method tractable for rea...

Exploration of clinical changes following a novel mobilisation technique for treatment of chronic low back pain: A single cohort design.

Science.gov (United States)

Hanson, Gail C; Jones, Bruce; Bacon, Catherine J; Moran, Robert W

2016-07-01

To explore clinical changes following a novel manual mobilisation technique, 24 participants who experienced 'moderate' to 'severe' chronic low back pain were recruited from new patients attending a suburban osteopathy clinic. The intervention was a previously undescribed side-lying mobilisation technique targeting the lumbosacral spine (median of 6 treatment sessions). After 8 weeks reductions were shown in Oswestry Disability Index of 15 points (95% CI: 9.3, 22.7; p pain intensity, disability and function improved in most participants following treatment. Further investigation is indicated using more robust research designs to compare this approach with other treatment approaches and usual care for the treatment of chronic low back pain. Copyright © 2015 Elsevier Ltd. All rights reserved.

The indirect costs and benefits of greenhouse gas mitigation

International Nuclear Information System (INIS)

Markandya, A.

1998-01-01

The indirect costs of GHG projects are very important in the evaluation of such projects. In many cases they are more important than the direct costs. This paper has shown what such costs consist of and how they may be estimated. As countries prepare their mitigation strategies, it is very important that they develop tools for the assessment of these indirect costs and use these tools in the appropriate manner. Hopefully, this paper will point them in the right direction. (au) 11 refs

Contextual modulation of reading rate for direct versus indirect speech quotations.

Science.gov (United States)

Yao, Bo; Scheepers, Christoph

2011-12-01

In human communication, direct speech (e.g., Mary said: "I'm hungry") is perceived to be more vivid than indirect speech (e.g., Mary said [that] she was hungry). However, the processing consequences of this distinction are largely unclear. In two experiments, participants were asked to either orally (Experiment 1) or silently (Experiment 2, eye-tracking) read written stories that contained either a direct speech or an indirect speech quotation. The context preceding those quotations described a situation that implied either a fast-speaking or a slow-speaking quoted protagonist. It was found that this context manipulation affected reading rates (in both oral and silent reading) for direct speech quotations, but not for indirect speech quotations. This suggests that readers are more likely to engage in perceptual simulations of the reported speech act when reading direct speech as opposed to meaning-equivalent indirect speech quotations, as part of a more vivid representation of the former. Copyright © 2011 Elsevier B.V. All rights reserved.

Thoracoscopy as a safe and effective technique for exploring calves affected with bovine respiratory disease

Directory of Open Access Journals (Sweden)

Natividad Perez-Villalobos

2017-03-01

Full Text Available Abstract Background Bovine respiratory disease (BRD is one of the leading causes of economic losses in the beef and dairy industry. Reliable antemortem tools for diagnosing BRD would improve the efficacy of treatment and reduce costs. Here we examined whether the relatively simple technique of thoracoscopy can support BRD diagnosis under field conditions. We also compared various equipment set-ups in order to optimize the safety and efficacy of the procedure. A total of 24 thoracoscopic procedures were performed in 17 calves diagnosed with BRD and in 2 healthy control calves. Rigid and flexible endoscopes and industrial videoscopes were tested using various insertion approaches. The suitability of the technique was assessed in terms of duration, volume of air extracted, visualization score, and image quality. Safety was assessed in terms of rectal temperature, body weight, breaths/min, presence of fibrinogen, pain score, recovery time, intraoperative complications and risk of laceration or threatening collapse. Results Insertion of a flexible endoscope via a right, dorso-caudal approach at the 5th intercostal space allowed complete examination of the right lung in 15 min, as well as identification of main lung lesions and adherences in calves with BRD, without compromising calf welfare. While the dorso-caudal approach was optimal, it was associated with substantial discomfort when rigid endoscopes were used, minimal complications or mortality due to thoracoscopy were observed up to 28 days after the procedure. Videoscopes were as safe and easy to use as endoscopes, but endoscopes provided better image quality. Conclusion This study provides the first field evidence that thoracoscopy can be safe to explore BRD-diseased calves. These results justify a larger study to rigorously assess the diagnostic performance of the technique.

INDIRECT AND EXPEDITE ASSESSMENT OF Ilex paraguariensis COMMERCIAL YIELD

Directory of Open Access Journals (Sweden)

Ivar Wendling

2016-09-01

Full Text Available Commercial biomass production is one of the main indicators for selecting erva-mate (Ilex paraguariensis progenies and clones. Traditional techniques to obtain such information depend on the harvesting of trees and there are some limitations involved, such as high cost and reduced convenience. Thus, in our research we evaluated the efficiency of indirect methods through commercial biomass estimation and score of productivity according to the different provenances, gender and morphotypes. In a provenances and progenies trial installed in 1997, two methodologies of visual analysis were evaluated in August 2015 (two years after the last harvest. For that reason, five expert evaluators determined, for each plant, an estimate of the commercial biomass (kg, and a grade, based on a score of productivity (0-10. In order to assess the productivity using traditional techniques, all plants were pruned and their commercial biomass (leaves and fine branches smaller than 7 mm diameter were harvested and weighed (kg.plant-1. The evaluations were performed in a randomized-block experiment with five repetitions, seven different provenances and 126 progenies, totaling 5,292 evaluated plants. The methods utilized were effective to estimate the commercial biomass. The evaluators showed accuracy, expressing efficiently the largest productivity obtained when comparing the means of provenances, plants gender and morphotypes. The highest correlations were observed in the general analysis of the means, and the estimation of commercial biomass was considered the best methodology for estimating the commercial biomass assessed in adult erva-mate plants.

From Hitting to Tattling to Gossip: An Evolutionary Rationale for the Development of Indirect Aggression

Directory of Open Access Journals (Sweden)

Gordon P. D. Ingram

2014-04-01

Full Text Available Adult humans are characterized by low rates of intra-group physical aggression. Since children tend to be more physically aggressive, an evolutionary developmental account shows promise for explaining how physical aggression is suppressed in adults. I argue that this is achieved partly through extended dominance hierarchies, based on indirect reciprocity and linguistic transmission of reputational information, mediated by indirectly aggressive competition. Reviewing the literature on indirect and related forms of aggression provides three pieces of evidence for the claim that evolutionarily old impulses towards physical aggression are socialized into indirect aggression in humans: (i physical aggression falls in early childhood over the same age range at which indirect aggression increases; (ii the same individuals engage in both direct and indirect aggression; and (iii socially dominant individuals practice indirect aggression more frequently. Consideration of the developmental course of indirect aggression is complemented by analysis of similar developments in verbal behaviors that are not always thought of as aggressive, namely tattling and gossip. An important puzzle concerns why indirect aggression becomes more covert, and tattling more derogated, in preadolescence and adolescence. This may be due to the development of new strategies aimed at renegotiating social identity and friendship alliances in the peer group.

From hitting to tattling to gossip: an evolutionary rationale for the development of indirect aggression.

Science.gov (United States)

Ingram, Gordon P D

2014-04-29

Adult humans are characterized by low rates of intra-group physical aggression. Since children tend to be more physically aggressive, an evolutionary developmental account shows promise for explaining how physical aggression is suppressed in adults. I argue that this is achieved partly through extended dominance hierarchies, based on indirect reciprocity and linguistic transmission of reputational information, mediated by indirectly aggressive competition. Reviewing the literature on indirect and related forms of aggression provides three pieces of evidence for the claim that evolutionarily old impulses towards physical aggression are socialized into indirect aggression in humans: (i) physical aggression falls in early childhood over the same age range at which indirect aggression increases; (ii) the same individuals engage in both direct and indirect aggression; and (iii) socially dominant individuals practice indirect aggression more frequently. Consideration of the developmental course of indirect aggression is complemented by analysis of similar developments in verbal behaviors that are not always thought of as aggressive, namely tattling and gossip. An important puzzle concerns why indirect aggression becomes more covert, and tattling more derogated, in preadolescence and adolescence. This may be due to the development of new strategies aimed at renegotiating social identity and friendship alliances in the peer group.

High convergence, indirect drive inertial confinement fusion experiments at Nova

International Nuclear Information System (INIS)

Lerche, R.A.; Cable, M.D.; Hatchett, S.P.; Caird, J.A.; Kilkenny, J.D.; Kornblum, H.N.; Lane, S.M.; Laumann, C.; Murphy, T.J.; Murray, J.; Nelson, M.B.; Phillion, D.W.; Powell, H.; Ress, D.

1996-01-01

High convergence, indirect drive implosion experiments have been done at the Nova Laser Facility. The targets were deuterium and deuterium/tritium filled, glass microballoons driven symmetrically by x rays produced in a surrounding uranium hohlraum. Implosions achieved convergence ratios of 24:1 with fuel densities of 19 g/cm 3 ; this is equivalent to the range required for the hot spot of ignition scale capsules. The implosions used a shaped drive and were well characterized by a variety of laser and target measurements. The primary measurement was the fuel density using the secondary neutron technique (neutrons from the reaction 2 H( 3 H,n) 4 He in initially pure deuterium fuel). Laser measurements include power, energy and pointing. Simultaneous measurement of neutron yield, fusion reaction rate, and x-ray images provide additional information about the implosion process. Computer models are in good agreement with measurement results. copyright 1996 American Institute of Physics

Jasmonate-deficient plants have reduced direct and indirect defences against herbivores

NARCIS (Netherlands)

Thaler, J.S.; Farag, M.A.; Paré, P.W.; Dicke, M.

2002-01-01

Plants employ a variety of defence mechanisms, some of which act directly by having a negative effect on herbivores and others that act indirectly by attracting natural enemies of herbivores. In this study we asked if a common jasmonate-signalling pathway links the regulation of direct and indirect

[Assessing the economic impact of cancer in Chile: a direct and indirect cost measurement based on 2009 registries].

Science.gov (United States)

Cid, Camilo; Herrera, Cristian; Rodríguez, Rodrigo; Bastías, Gabriel; Jiménez, Jorge

2016-08-02

This paper aims to determine the economic impact that cancer represents to Chile, exploring the share of costs for the most important cancers and the differences between the public and private sector. We used the cost of illness methodology, through the assessment of the direct and indirect costs associated with cancer treatment. Data was obtained from 2009 registries of the Chilean Ministry of Health and the Superintendence of Health. Indirect costs were calculated by days of job absenteeism and potential years of life lost. Over US$ 2.1 billion were spent on cancer in 2009, which represents almost 1% of Chile’s Gross Domestic Product. The direct per capita cost was US$ 47. Indirect costs were 1.92 times more than direct costs. The three types of cancer that embody the highest share of costs were gastric cancer (17.6%), breast cancer (7%) and prostate cancer (4.2%) in the public sector, and breast cancer (14%), lung cancer (7.5%) and prostate cancer (4.1%) in the private sector. On average men spent 30.33% more than women. There are few studies of this kind in Chile and the region. The country can be classified as having a cancer economic impact below the average of those in European Union countries. We expect that this information can be used to develop access policies and resource allocation decision making, and as a first step into further cancer-costing studies in Chile and the Latin American and Caribbean region.

INDIRECT TAXATION TRENDS IN THE EUROPEAN UNION MEMBER STATES

Directory of Open Access Journals (Sweden)

MARIUS CRISTIAN MILOŞ

2014-12-01

Full Text Available The objective of this paper is to outline the recent dynamics of the indirect taxation in the European Union member states, with a special focus on the Romanian case. We could notice that indirect taxation continues to play an important role for all the member states, in their attempt to recover from the global economic crisis. Morover, we have presented some of the recent changes in the legislative frameworks, which happened with a rather rapid pace, and contributed to a rather challenging business climate.

(13)C-(15)N correlation via unsymmetrical indirect covariance NMR: application to vinblastine.

Science.gov (United States)

Martin, Gary E; Hilton, Bruce D; Blinov, Kirill A; Williams, Antony J

2007-12-01

Unsymmetrical indirect covariance processing methods allow the derivation of hyphenated 2D NMR data from the component 2D spectra, potentially circumventing the acquisition of the much lower sensitivity hyphenated 2D NMR experimental data. Calculation of HSQC-COSY and HSQC-NOESY spectra from GHSQC, COSY, and NOESY spectra, respectively, has been reported. The use of unsymmetrical indirect covariance processing has also been applied to the combination of (1)H- (13)C GHSQC and (1)H- (15)N long-range correlation data (GHMBC, IMPEACH, or CIGAR-HMBC). The application of unsymmetrical indirect covariance processing to spectra of vinblastine is now reported, specifically the algorithmic extraction of (13)C- (15)N correlations via the unsymmetrical indirect covariance processing of the combination of (1)H- (13)C GHSQC and long-range (1)H- (15)N GHMBC to produce the equivalent of a (13)C- (15)N HSQC-HMBC correlation spectrum. The elimination of artifact responses with aromatic solvent-induced shifts (ASIS) is shown in addition to a method of forecasting potential artifact responses through the indirect covariance processing of the GHSQC spectrum used in the unsymmetrical indirect covariance processing.

Leveling the playing field of transportation fuels: Accounting for indirect emissions of natural gas

International Nuclear Information System (INIS)

Sexton, Steven; Eyer, Jonathan

2016-01-01

Natural gas transportation fuels are credited in prior studies with greenhouse gas emissions savings relative to petroleum-based fuels and relative to the total emissions of biofuels. These analyses, however, overlook a source of potentially large indirect emissions from natural gas transportation fuels, namely the emissions from incremental coal-fired generation caused by price-induced substitutions away from natural-gas-fired electricity generation. Because coal-fired generation emits substantially more greenhouse gases and criteria air pollutants than natural-gas-fired generation, this indirect coal-use change effect diminishes potential emissions savings from natural gas transportation fuels. Estimates from a parameterized multi-market model suggest the indirect coal-use change effect rivals in magnitude the indirect land-use change effect of biofuels and renders natural gas fuels as carbon intensive as petroleum fuels. - Highlights: •Natural gas used in transport causes indirect emissions in the electricity sector. •These emissions result from increased coal use in electricity generation. •They rival in magnitude indirect land use change (ILUC) emissions of biofuels. •Natural gas fuels are estimated to be as carbon intensive as the petroleum fuels. •Policy ignores indirect emissions from natural gas.

Interactive Network Exploration with Orange

Directory of Open Access Journals (Sweden)

Miha Štajdohar

2013-04-01

Full Text Available Network analysis is one of the most widely used techniques in many areas of modern science. Most existing tools for that purpose are limited to drawing networks and computing their basic general characteristics. The user is not able to interactively and graphically manipulate the networks, select and explore subgraphs using other statistical and data mining techniques, add and plot various other data within the graph, and so on. In this paper we present a tool that addresses these challenges, an add-on for exploration of networks within the general component-based environment Orange.

Indirect reciprocity with trinary reputations.

Science.gov (United States)

Tanabe, Shoma; Suzuki, Hideyuki; Masuda, Naoki

2013-01-21

Indirect reciprocity is a reputation-based mechanism for cooperation in social dilemma situations when individuals do not repeatedly meet. The conditions under which cooperation based on indirect reciprocity occurs have been examined in great details. Most previous theoretical analysis assumed for mathematical tractability that an individual possesses a binary reputation value, i.e., good or bad, which depends on their past actions and other factors. However, in real situations, reputations of individuals may be multiple valued. Another puzzling discrepancy between the theory and experiments is the status of the so-called image scoring, in which cooperation and defection are judged to be good and bad, respectively, independent of other factors. Such an assessment rule is found in behavioral experiments, whereas it is known to be unstable in theory. In the present study, we fill both gaps by analyzing a trinary reputation model. By an exhaustive search, we identify all the cooperative and stable equilibria composed of a homogeneous population or a heterogeneous population containing two types of players. Some results derived for the trinary reputation model are direct extensions of those for the binary model. However, we find that the trinary model allows cooperation under image scoring under some mild conditions. Copyright © 2012 Elsevier Ltd. All rights reserved.

Media bias under direct and indirect government control: when is the bias smaller?

OpenAIRE

Abhra Roy

2015-01-01

We present an analytical framework to compare media bias under direct and indirect government control. In this context, we show that direct control can lead to a smaller bias and higher welfare than indirect control. We further show that the size of the advertising market affects media bias only under direct control. Media bias, under indirect control, is not affected by the size of the advertising market.

Indirectly detected chemical shift correlation NMR spectroscopy in solids under fast magic angle spinning

Energy Technology Data Exchange (ETDEWEB)

Mao, Kanmi [Iowa State Univ., Ames, IA (United States)

2011-01-01

The development of fast magic angle spinning (MAS) opened up an opportunity for the indirect detection of insensitive low-γ nuclei (e.g., ¹³C and ¹⁵N) via the sensitive high-{gamma} nuclei (e.g., ¹H and ¹⁹F) in solid-state NMR, with advanced sensitivity and resolution. In this thesis, new methodology utilizing fast MAS is presented, including through-bond indirectly detected heteronuclear correlation (HETCOR) spectroscopy, which is assisted by multiple RF pulse sequences for ¹H-¹H homonuclear decoupling. Also presented is a simple new strategy for optimization of ¹H-¹H homonuclear decoupling. As applications, various classes of materials, such as catalytic nanoscale materials, biomolecules, and organic complexes, are studied by combining indirect detection and other one-dimensional (1D) and two-dimensional (2D) NMR techniques. Indirectly detected through-bond HETCOR spectroscopy utilizing refocused INEPT (INEPTR) mixing was developed under fast MAS (Chapter 2). The time performance of this approach in ¹H detected 2D ¹H{l_brace}¹³C{r_brace} spectra was significantly improved, by a factor of almost 10, compared to the traditional ¹³C detected experiments, as demonstrated by measuring naturally abundant organic-inorganic mesoporous hybrid materials. The through-bond scheme was demonstrated as a new analytical tool, which provides complementary structural information in solid-state systems in addition to through-space correlation. To further benefit the sensitivity of the INEPT transfer in rigid solids, the combined rotation and multiple-pulse spectroscopy (CRAMPS) was implemented for homonuclear ¹H decoupling under fast MAS (Chapter 3). Several decoupling schemes (PMLG5_m^$\\bar{x}$, PMLG5_mm^$\\bar{x}$x and SAM3) were analyzed to maximize the performance of through-bond transfer based

Light indirectly mediates bivalve habitat modification and impacts on seagrass

DEFF Research Database (Denmark)

Castorani, Max C. N.; Glud, Ronnie; Hasler-Sheetal, Harald

2015-01-01

Environmental context may influence the sign, strength, andmechanisms of species interactions but few studies have experimentally tested the potential for abiotic conditions to mediate interactions through multiple cooccurring stress pathways. Abiotic conditionsmay mediate species interactions...... by directly or indirectly influencing the effects of habitat-modifying organisms that are capable of simultaneously ameliorating and exacerbating multiple stressors. Itwas hypothesized that light availability changes seagrassmetabolismand thereby indirectly regulates bivalve habitat modification...

Uranium exploration in Ecuador

International Nuclear Information System (INIS)

Severne, B.; Penaherrera, P.F.; Fiallos, V.S.

1981-01-01

The 600-km segment of the Andean Cordillera in Ecuador includes zones that can be correlated, geologically, with uranium districts elsewhere in the Andes. It is believed that these essentially unexplored zones have the potential for economic uranium mineralization. Exploration activity to date has been limited, although it has involved both geochemical and radiometric techniques to evaluate geological concepts. Minor uranium occurrences (with chemical analyses up to 100 ppm) have been encountered, which provide further incentive to commence large-scale systematic exploration. It is recognized that a very large exploration budget and considerable technical expertise will be required to ensure exploration success. Consequently, participation by groups of proven capability from other countries will be sought for Ecuador's national exploration programme. (author)

Mode-selective symmetry control for indirect-drive inertial confinement fusion hohlraums

International Nuclear Information System (INIS)

Vesey, R. A.; Slutz, S. A.; Herrmann, M. C.; Mehlhorn, T. A.; Campbell, R. B.

2008-01-01

Achieving a high degree of radiation symmetry is a critical feature of target designs for indirect-drive inertial confinement fusion. Typically, the radiation flux incident on the capsule is required to be uniform to 1% or better. It is generally possible to design a hohlraum that provides low values of higher-order asymmetry (Legendre mode P 10 and above) due to geometric averaging effects. Because low-order intrinsic asymmetry (e.g., Legendre modes P 2 and P 4 ) are less strongly reduced by geometric averaging alone, the development of innovative control techniques has been an active area of research in the inertial fusion community over the years. Shields placed inside the hohlraum are one example of a technique that has often been proposed and incorporated into hohlraum target designs. Simple mathematical considerations are presented indicating that radiation shields may be designed to specifically tune lower-order modes (e.g., P 4 ) without deleterious effects on the higher order modes. Two-dimensional view factor and radiation-hydrodynamics simulations confirm these results and support such a path to achieving a highly symmetric x-ray flux. The term ''mode-selective'' is used because these shields, essentially ring structures offset from the capsule, are designed to affect only a specific Legendre mode (or multiple modes) of interest

Indirect measurements of X-ray spectra

International Nuclear Information System (INIS)

Mainardi, R.T.

2006-01-01

To the effects of measuring the spectral distribution of the radiation emitted by the x-ray tubes and electron accelerators, numerous procedures that are grouped in two big categories exist at the present time: direct and indirect methods. The first ones use high resolution detectors that should be positioned, together with the appropriate collimator, in the direction of the x ray beam. The user should be an expert in the use and correction of the obtained data by the different effects that affect the detector operation such as efficiency and resolution in terms of the energy of the detected radiation. The indirect procedures, although its are more simple to use, its also require a considerable space along the beam to position the ionization chamber and the necessary absorbents to construct by this way the denominated attenuation curve. We will analyze the operation principle of the indirect methods and a new proposal in which such important novelties are introduced as the beam dispersion to avoid to measure along the main beam and that of determination of the attenuation curve in simultaneous form. By this way, with a single shot of the tube, the attenuation curve is measured, being necessary at most a shot of additional calibration to know the relative response of the detectors used in the experimental array. The physical processes involved in the obtaining of an attenuation curve are very well well-known and this it finishes it can be theoretically calculated if the analytic form of the spectrum is supposed well-known. Finally, we will see a spectra reconstruction example with the Kramers parametric form and comparisons with numeric simulations carried out with broadly validated programs as well as the possibility of the use of solid state dosemeters in the obtention of the attenuation curve. (Author)

Photogrammetry of the human brain: a novel method for 3D the quantitative exploration of the structural connectivity in neurosurgery and neurosciences.

Science.gov (United States)

De Benedictis, Alessandro; Nocerino, Erica; Menna, Fabio; Remondino, Fabio; Barbareschi, Mattia; Rozzanigo, Umberto; Corsini, Francesco; Olivetti, Emanuele; Marras, Carlo Efisio; Chioffi, Franco; Avesani, Paolo; Sarubbo, Silvio

2018-04-13

Anatomical awareness of brain's structural connectivity is mandatory for neurosurgeons, to select the most effective approaches for brain resections. Although standard micro-dissection is a validated technique to investigate the different white matter (WM) pathways and to verify results coming from tractography, the possibility of an interactive exploration of the specimens and of a reliable acquisition of quantitative information has not been described so far. Photogrammetry is a well-established technique allowing an accurate metrology on highly defined 3D-models. The aim of this work is to propose the application of photogrammetric technique for supporting the 3D-exploration and the quantitative analysis on the cerebral WM connectivity. The main peri-sylvian pathways, including the superior longitudinal fascicle (SLF) and the arcuate fascicle (AF) were exposed using the Klingler's technique. The photogrammetric acquisition followed each dissection step. The point-clouds were registered to a reference MRI of the specimen. All the acquisitions were co-registered into an open-source model. We analyzed five steps, including: the cortical surface, the short intergyral fibers, the indirect posterior and anterior SLF, and the AF. The co-registration between the MRI mesh and the point-clouds models resulted highly accurate. Multiple measures of distances between specific cortical landmarks and WM tracts were collected on the photogrammetric model. Photogrammetry allows an accurate 3D-reproduction of WM anatomy, and the acquisition of unlimited quantitative data directly on the real specimen during the post-dissection analysis. These results open many new promising neuroscientific and educational perspectives, also for optimizing the quality of neurosurgical treatments. Copyright © 2018 Elsevier Inc. All rights reserved.

Groupwise information sharing promotes ingroup favoritism in indirect reciprocity.

Science.gov (United States)

Nakamura, Mitsuhiro; Masuda, Naoki

2012-11-05

Indirect reciprocity is a mechanism for cooperation in social dilemma situations. In indirect reciprocity, an individual is motivated to help another to acquire a good reputation and receive help from others afterwards. Another aspect of human cooperation is ingroup favoritism, whereby individuals help members in their own group more often than those in other groups. Ingroup favoritism is a puzzle for the theory of cooperation because it is not easily evolutionarily stable. In the context of indirect reciprocity, ingroup favoritism has been shown to be a consequence of employing a double standard when assigning reputations to ingroup and outgroup members. An example of such a double standard is the situation in which helping an ingroup member is regarded as good, whereas the same action toward an outgroup member is regarded as bad. We analyze a computational model of indirect reciprocity in which information sharing is conducted groupwise. In our model, individuals play social dilemma games within and across groups, and the information about their reputations is shared within each group. We show that evolutionarily stable ingroup favoritism emerges even if all the players use the same reputation assignment rule regardless of group (i.e., a single standard). Two reputation assignment rules called simple standing and stern judging yield ingroup favoritism; under these rules, cooperation with (defection against) good individuals is regarded as good (bad) and defection against bad individuals is regarded as good. Stern judging induces much stronger ingroup favoritism than does simple standing. Simple standing and stern judging are evolutionarily stable against each other when groups employing different assignment rules compete and the number of groups is sufficiently large. In addition, we analytically show as a limiting case that homogeneous populations of reciprocators that use reputations are unstable when individuals independently infer reputations of individuals

Groupwise information sharing promotes ingroup favoritism in indirect reciprocity

Directory of Open Access Journals (Sweden)

Nakamura Mitsuhiro

2012-11-01

Full Text Available Abstract Background Indirect reciprocity is a mechanism for cooperation in social dilemma situations. In indirect reciprocity, an individual is motivated to help another to acquire a good reputation and receive help from others afterwards. Another aspect of human cooperation is ingroup favoritism, whereby individuals help members in their own group more often than those in other groups. Ingroup favoritism is a puzzle for the theory of cooperation because it is not easily evolutionarily stable. In the context of indirect reciprocity, ingroup favoritism has been shown to be a consequence of employing a double standard when assigning reputations to ingroup and outgroup members. An example of such a double standard is the situation in which helping an ingroup member is regarded as good, whereas the same action toward an outgroup member is regarded as bad. Results We analyze a computational model of indirect reciprocity in which information sharing is conducted groupwise. In our model, individuals play social dilemma games within and across groups, and the information about their reputations is shared within each group. We show that evolutionarily stable ingroup favoritism emerges even if all the players use the same reputation assignment rule regardless of group (i.e., a single standard. Two reputation assignment rules called simple standing and stern judging yield ingroup favoritism; under these rules, cooperation with (defection against good individuals is regarded as good (bad and defection against bad individuals is regarded as good. Stern judging induces much stronger ingroup favoritism than does simple standing. Simple standing and stern judging are evolutionarily stable against each other when groups employing different assignment rules compete and the number of groups is sufficiently large. In addition, we analytically show as a limiting case that homogeneous populations of reciprocators that use reputations are unstable when individuals

Exploring FPGA‐Based Lock‐In Techniques for Brain  Monitoring Applications

Directory of Open Access Journals (Sweden)

Giuseppe Costantino Giaconia

2017-03-01

Full Text Available Functional near‐infrared spectroscopy (fNIRS systems for e‐health applications usually suffer from poor signal detection, mainly due to a low end‐to‐end signal‐to‐noise ratio of the electronics chain. Lock‐in amplifiers (LIA historically represent a powerful technique helping to improve performance in such circumstances. In this work a digital LIA system, based on a Zynq® field programmable gate array (FPGA has been designed and implemented, in an attempt to explore if this technique might improve fNIRS system performance. More broadly, FPGA‐based solution flexibility has been investigated, with particular emphasis applied to digital filter parameters, needed in the digital LIA, and its impact on the final signal detection and noise rejection capability has been evaluated. The realized architecture was a mixed solution between VHDL hardware modules and software modules, running within a microprocessor. Experimental results have shown the goodness of the proposed solutions and comparative details among different implementations will be detailed. Finally a key aspect taken into account throughout the design was its modularity, allowing an easy increase of the input channels while avoiding the growth of the design cost of the electronics system.

Indirect revascularization surgery for moyamoya disease in children and its special considerations

Directory of Open Access Journals (Sweden)

Kyu-Chang Wang

2012-11-01

Full Text Available Moyamoya disease (MMD is the most common pediatric cerebrovascular disease in Far Eastern countries. In children, MMD frequently manifests as ischemic symptomatology. Cerebral perfusion gradually decreases as the disease progresses, which often leads to cerebral infarction. The benefits of revascularization surgery, whether direct or indirect, have been well established in MMD patients with ischemic symptoms. In adults, the increase in cerebral blood flow achieved with indirect revascularization is often unsatisfactory, and direct revascularization is usually feasible. In children, however, direct revascularization is frequently technically not feasible, whereas the response to indirect revascularization is excellent, although 1 or 2 weeks are required for stabilization of symptoms. The authors describe surgical procedures and perioperative care in indirect revascularization for MMD. In addition, special considerations with regard to very young patients, patients with recent cerebral infarction, and patients with hyperthyroidism are discussed.

Uranium exploration, mining and ore enrichment techniques

International Nuclear Information System (INIS)

Fuchs, H.D.; Wentzlau, D.

1985-01-01

The paper describes the different types of uranium deposits and their importance. It is shown that during the present depressed uranium market situation, mainly high grade deposits such as unconformity-related deposits can be mined economically. The different successive exploration steps are outlined including methods used for uranium. Uranium mining does not greatly differ from normal mining, but the uranium metallurgy needs its own specialized but already classic technology. Only a relative small amount of uranium can be expected from projects where uranium is produced by in situ leach methods or by extraction from phosphoric acid. A short summary of investment costs and operating costs is given for an average uranium mine. The last chapter deals with the definition of different reserve categories and outlines the uranium reserves of the western world including the uranium production (1983) and the expected uranium production capacity for 1985 and 1990. (orig.) [de

Friends of friends: are indirect connections in social networks important to animal behaviour?

Science.gov (United States)

Brent, Lauren J N

2015-05-01

Friend of a friend relationships, or the indirect connections between people, influence our health, well-being, financial success and reproductive output. As with humans, social behaviours in other animals often occur within a broad interconnected network of social ties. Yet studies of animal social behaviour tend to focus on associations between pairs of individuals. With the increase in popularity of social network analysis, researchers have started to look beyond the dyad to examine the role of indirect connections in animal societies. Here, I provide an overview of the new knowledge that has been uncovered by these studies. I focus on research that has addressed both the causes of social behaviours, i.e. the cognitive and genetic basis of indirect connections, as well as their consequences, i.e. the impact of indirect connections on social cohesion, information transfer, cultural practices and fitness. From these studies, it is apparent that indirect connections play an important role in animal behaviour, although future research is needed to clarify their contribution.

Current indirect fitness and future direct fitness are not incompatible.

Science.gov (United States)

Brahma, Anindita; Mandal, Souvik; Gadagkar, Raghavendra

2018-02-01

In primitively eusocial insects, many individuals function as workers despite being capable of independent reproduction. Such altruistic behaviour is usually explained by the argument that workers gain indirect fitness by helping close genetic relatives. The focus on indirect fitness has left open the question of whether workers are also capable of getting direct fitness in the future in spite of working towards indirect fitness in the present. To investigate this question, we recorded behavioural profiles of all wasps on six naturally occurring nests of Ropalidia marginata , and then isolated all wasps in individual plastic boxes, giving them an opportunity to initiate nests and lay eggs. We found that 41% of the wasps successfully did so. Compared to those that failed to initiate nests, those that did were significantly younger, had significantly higher frequency of self-feeding behaviour on their parent nests but were not different in the levels of work performed in the parent nests. Thus ageing and poor feeding, rather than working for their colonies, constrain individuals for future independent reproduction. Hence, future direct fitness and present work towards gaining indirect fitness are not incompatible, making it easier for worker behaviour to be selected by kin selection or multilevel selection. © 2018 The Author(s).

Direct-indirect mixed implosion mode in heavy ion inertial fusion

International Nuclear Information System (INIS)

Kawata, S.; Miyazawa, K.; Kikuchi, T.; Someya, T.

2007-01-01

In order to realize an effective implosion, beam illumination non-uniformity on a fuel target must be suppressed less than a few percent. In this study, a direct-indirect mixture implosion mode is proposed and discussed in heavy ion beam (HIB) inertial confinement fusion (HIF) in order to release sufficient fusion energy in a robust manner. On the other hand, the HIB illumination non-uniformity depends strongly on a target displacement dz from the center of a fusion reactor chamber. In a direct-driven implosion mode, dz of ∼20 μm was tolerable, and in an indirect-implosion mode, dz of ∼100 μm was allowable. In the direct-indirect mixture mode target, a low-density foam layer is inserted, and the radiation energy is confined in the foam layer. In the foam layer, the radiation transport is expected to smooth the HIB illumination non-uniformity in the lateral direction. Two-dimensional implosion simulations are performed, and show that the HIB illumination non-uniformity is well smoothed in the direct-indirect mixture target. Our simulation results present that a large pellet displacement of approximately a few hundred microns is allowed in order to obtain a sufficient fusion energy output in HIF

Effects of indirect bandgap top cells in a monolithic cascade cell structure

Science.gov (United States)

Curtis, H. B.; Godlewski, M. P.

1982-01-01

The effect of having a slightly indirect top cell in a three junction cascade monolithic stack is calculated. The minority carrier continuity equations are utilized to calculate individual junction performance. Absorption coefficient curves for general III-V compounds are calculated for a variety of direct and indirect gap materials. The results indicate that for a small excursion into the indirect region, (about 0.1 eV), the loss of efficiency is acceptably small (less than 2.5 percent) and considerably less than attempting to make the top junction a smaller direct bandgap.

Design refinement of multilayer optical thin film devices with two optimization techniques

International Nuclear Information System (INIS)

Apparao, K.V.S.R.

1992-01-01

The design efficiency of two different optimization techniques of designing multilayer optical thin film devices is compared. Ten different devices of varying complexities are chosen as design examples for the comparison. The design refinement efficiency and the design parameter characteristics of all the sample designs obtained with the two techniques are compared. The results of the comparison demonstrate that the new method of design developed using damped least squares technique with indirect derivatives give superior and efficient designs compared to the method developed with direct derivatives. (author). 23 refs., 4 tabs., 14 figs

Indirect effects of predators control herbivore richness and abundance in a benthic eelgrass (Zostera marina) mesograzer community.

Science.gov (United States)

Amundrud, Sarah L; Srivastava, Diane S; O'Connor, Mary I

2015-07-01

Herbivore communities can be sensitive to changes in predator pressure (top-down effects) and resource availability (bottom-up effects) in a wide range of systems. However, it remains unclear whether such top-down and bottom-up effects reflect direct impacts of predators and/or resources on herbivores, or are indirect, reflecting altered interactions among herbivore species. We quantified direct and indirect effects of bottom-up and top-down processes on an eelgrass (Zostera marina) herbivore assemblage. In a field experiment, we factorially manipulated water column nutrients (with Osmocote(™) slow-release fertilizer) and predation pressure (with predator exclusion cages) and measured the effects on herbivore abundance, richness and beta diversity. We examined likely mechanisms of community responses by statistically exploring the response of individual herbivore species to trophic manipulations. Predators increased herbivore richness and total abundance, in both cases through indirect shifts in community composition. Increases in richness occurred through predator suppression of common gammarid amphipod species (Monocorophium acherusicum and Photis brevipes), permitting the inclusion of rarer gammarid species (Aoroides columbiae and Pontogeneia rostrata). Increased total herbivore abundance reflected increased abundance of a caprellid amphipod species (Caprella sp.), concurrent with declines in the abundance of other common species. Furthermore, predators decreased beta diversity by decreasing variability in Caprella sp. abundance among habitat patches. Osmocote(™) fertilization increased nutrient concentrations locally, but nutrients dissipated to background levels within 3 m of the fertilizer. Nutrient addition weakly affected the herbivore assemblage, not affecting richness and increasing total abundance by increasing one herbivore species (Caprella sp.). Nutrient addition did not affect beta diversity. We demonstrated that assemblage-level effects of

Towards ABET accreditation for a SWE program: alternative student assessment techniques

International Nuclear Information System (INIS)

Alghamdi, A.; Nasir, M.; Alnafjan, K.

2011-01-01

This paper describes assessment techniques utilized for assessing undergraduate students studying in a software engineering program. The purpose behind this work is to get the program accredited by the Accreditation Board of Engineering and Technology (ABET). Therefore, a number of applied direct and indirect assessment techniques are described. These techniques are implemented towards the end of the semester to assess the extent to which the student and course outcomes are satisfied. Consequently, results are obtained and analyzed and various learning issues are eventually identified. Finally, the paper provides suggestions for improvement in course delivery as well as learning mechanism. (author)

Indirect processes in electron-ion scattering

International Nuclear Information System (INIS)

Bottcher, C.; Griffin, D.C.; Pindzola, M.S.; Phaneuf, R.A.

1983-10-01

A summary is given of an informal workshop held at Oak Ridge National Laboratory on June 22-23, 1983, in which the current status of theoretical calculations of indirect processes in electron-ion scattering was reviewed. Processes of particular interest in astrophysical and fusion plasmas were emphasized. Topics discussed include atomic structure effects, electron-impact ionization, and dielectronic recombination

Indirect effects of recreation on wildlife

Science.gov (United States)

David N. Cole; Peter B. Landres

1995-01-01

Most of this book focuses on direct impacts to wildlife that result from contact with people. The purpose of our chapter is to provide a broad overview of the indirect influences that recreation has on wildlife. Recreational activities can change the habitat of an animal. This, in turn, affects the behavior, survival, reproduction, and distribution of individuals....

Indirect processes in electron-ion scattering

Energy Technology Data Exchange (ETDEWEB)

Bottcher, C.; Griffin, D.C.; Pindzola, M.S.; Phaneuf, R.A.

1983-10-01

A summary is given of an informal workshop held at Oak Ridge National Laboratory on June 22-23, 1983, in which the current status of theoretical calculations of indirect processes in electron-ion scattering was reviewed. Processes of particular interest in astrophysical and fusion plasmas were emphasized. Topics discussed include atomic structure effects, electron-impact ionization, and dielectronic recombination.

Development of a volumetric projection technique for the digital evaluation of field of view.

Science.gov (United States)

Marshall, Russell; Summerskill, Stephen; Cook, Sharon

2013-01-01

Current regulations for field of view requirements in road vehicles are defined by 2D areas projected on the ground plane. This paper discusses the development of a new software-based volumetric field of view projection tool and its implementation within an existing digital human modelling system. In addition, the exploitation of this new tool is highlighted through its use in a UK Department for Transport funded research project exploring the current concerns with driver vision. Focusing specifically on rearwards visibility in small and medium passenger vehicles, the volumetric approach is shown to provide a number of distinct advantages. The ability to explore multiple projections of both direct vision (through windows) and indirect vision (through mirrors) provides a greater understanding of the field of view environment afforded to the driver whilst still maintaining compatibility with the 2D projections of the regulatory standards. Field of view requirements for drivers of road vehicles are defined by simplified 2D areas projected onto the ground plane. However, driver vision is a complex 3D problem. This paper presents the development of a new software-based 3D volumetric projection technique and its implementation in the evaluation of driver vision in small- and medium-sized passenger vehicles.

3-Year-Old Children Make Relevance Inferences in Indirect Verbal Communication

Science.gov (United States)

Schulze, Cornelia; Grassmann, Susanne; Tomasello, Michael

2013-01-01

Three studies investigated 3-year-old children's ability to determine a speaker's communicative intent when the speaker's overt utterance related to that intent only indirectly. Studies 1 and 2 examined children's comprehension of indirectly stated requests (e.g., "I find Xs good" can imply, in context, a request for…

Coexistence in a One-Predator, Two-Prey System with Indirect Effects

Directory of Open Access Journals (Sweden)

Renato Colucci

2013-01-01

Full Text Available We study the dynamics of a one-predator, two-prey system in which the predator has an indirect effect on the preys. We show that, in presence of the indirect effect term, the system admits coexistence of the three populations while, if we disregard it, at least one of the populations goes to extinction.

Indirect effects of land-use legacies determine tree colonization patterns in abandoned heathland

DEFF Research Database (Denmark)

Kepfer Rojas, Sebastian; Verheyen, Kris; Johannsen, Vivian Kvist

2015-01-01

of tree/shrubs in the heathland. Further, we used high-resolution LiDAR data to classify the vegetation and identify forest patches. In the analysis, we first used a logistic mixed model to test whether colonization of tree and shrub species differed between areas with different land-use history......Questions How do land-use legacies and distance to forest patches influence tree colonization at a post-agricultural heathland? Are colonizing species with different life-history traits affected differently by these factors? Is the effect of increased nutrient availability from land-use legacies...... and whether it was influenced by the distance to forest patches and life-history traits (seed mass) of colonizing species. Then, to determine how different factors influence colonization, we explored the direct and indirect relationships among nutrient availability, density of adult trees, canopy cover, cover...

Developing the MD Explorer

Science.gov (United States)

Howie, Philip V.

1993-04-01

The MD Explorer is an eight-seat twin-turbine engine helicopter which is being developed using integrated product definition (IPD) team methodology. New techniques include NOTAR antitorque system for directional control, a composite fuselage, an all-composite bearingless main rotor, and digital cockpit displays. Three-dimensional CAD models are the basis of the entire Explorer design. Solid models provide vendor with design clarification, removing much of the normal drawing interpretation errors.

Early time implosion symmetry from two-axis shock-timing measurements on indirect drive NIF experiments

Energy Technology Data Exchange (ETDEWEB)

Moody, J. D., E-mail: moody4@llnl.gov; Robey, H. F.; Celliers, P. M.; Munro, D. H.; Barker, D. A.; Baker, K. L.; Döppner, T.; Hash, N. L.; Berzak Hopkins, L.; LaFortune, K.; Landen, O. L.; LePape, S.; MacGowan, B. J.; Ralph, J. E.; Ross, J. S.; Widmayer, C. [Lawrence Livermore National Laboratory, Livermore, California 94551 (United States); Nikroo, A.; Giraldez, E. [General Atomics, San Diego, California 92186-5608 (United States); Boehly, T. [Laboratory for Laser Energetics, Rochester, New York 14623-1299 (United States)

2014-09-15

An innovative technique has been developed and used to measure the shock propagation speed along two orthogonal axes in an inertial confinement fusion indirect drive implosion target. This development builds on an existing target and diagnostic platform for measuring the shock propagation along a single axis. A 0.4 mm square aluminum mirror is installed in the ablator capsule which adds a second orthogonal view of the x-ray-driven shock speeds. The new technique adds capability for symmetry control along two directions of the shocks launched in the ablator by the laser-generated hohlraum x-ray flux. Laser power adjustments in four different azimuthal cones based on the results of this measurement can reduce time-dependent symmetry swings during the implosion. Analysis of a large data set provides experimental sensitivities of the shock parameters to the overall laser delivery and in some cases shows the effects of laser asymmetries on the pole and equator shock measurements.

Lifestyle factors, direct and indirect costs for a Brazilian airline company

Science.gov (United States)

Rabacow, Fabiana Maluf; Luiz, Olinda do Carmo; Malik, Ana Maria; Burdorf, Alex

2014-01-01

OBJECTIVE To analyze lifestyle risk factors related to direct healthcare costs and the indirect costs due to sick leave among workers of an airline company in Brazil. METHODS In this longitudinal 12-month study of 2,201 employees of a Brazilian airline company, the costs of sick leave and healthcare were the primary outcomes of interest. Information on the independent variables, such as gender, age, educational level, type of work, stress, and lifestyle-related factors (body mass index, physical activity, and smoking), was collected using a questionnaire on enrolment in the study. Data on sick leave days were available from the company register, and data on healthcare costs were obtained from insurance records. Multivariate linear regression analysis was used to investigate the association between direct and indirect healthcare costs with sociodemographic, work, and lifestyle-related factors. RESULTS Over the 12-month study period, the average direct healthcare expenditure per worker was US$505.00 and the average indirect cost because of sick leave was US$249.00 per worker. Direct costs were more than twice the indirect costs and both were higher in women. Body mass index was a determinant of direct costs and smoking was a determinant of indirect costs. CONCLUSIONS Obesity and smoking among workers in a Brazilian airline company were associated with increased health costs. Therefore, promoting a healthy diet, physical activity, and anti-tobacco campaigns are important targets for health promotion in this study population. PMID:26039398

Lifestyle factors, direct and indirect costs for a Brazilian airline company.

Science.gov (United States)

Rabacow, Fabiana Maluf; Luiz, Olinda do Carmo; Malik, Ana Maria; Burdorf, Alex

2014-12-01

OBJECTIVE To analyze lifestyle risk factors related to direct healthcare costs and the indirect costs due to sick leave among workers of an airline company in Brazil. METHODS In this longitudinal 12-month study of 2,201 employees of a Brazilian airline company, the costs of sick leave and healthcare were the primary outcomes of interest. Information on the independent variables, such as gender, age, educational level, type of work, stress, and lifestyle-related factors (body mass index, physical activity, and smoking), was collected using a questionnaire on enrolment in the study. Data on sick leave days were available from the company register, and data on healthcare costs were obtained from insurance records. Multivariate linear regression analysis was used to investigate the association between direct and indirect healthcare costs with sociodemographic, work, and lifestyle-related factors. RESULTS Over the 12-month study period, the average direct healthcare expenditure per worker was US$505.00 and the average indirect cost because of sick leave was US$249.00 per worker. Direct costs were more than twice the indirect costs and both were higher in women. Body mass index was a determinant of direct costs and smoking was a determinant of indirect costs. CONCLUSIONS Obesity and smoking among workers in a Brazilian airline company were associated with increased health costs. Therefore, promoting a healthy diet, physical activity, and anti-tobacco campaigns are important targets for health promotion in this study population.

Lifestyle factors, direct and indirect costs for a Brazilian airline company

Directory of Open Access Journals (Sweden)

Fabiana Maluf Rabacow

2014-12-01

Full Text Available OBJECTIVE To analyze lifestyle risk factors related to direct healthcare costs and the indirect costs due to sick leave among workers of an airline company in Brazil. METHODS In this longitudinal 12-month study of 2,201 employees of a Brazilian airline company, the costs of sick leave and healthcare were the primary outcomes of interest. Information on the independent variables, such as gender, age, educational level, type of work, stress, and lifestyle-related factors (body mass index, physical activity, and smoking, was collected using a questionnaire on enrolment in the study. Data on sick leave days were available from the company register, and data on healthcare costs were obtained from insurance records. Multivariate linear regression analysis was used to investigate the association between direct and indirect healthcare costs with sociodemographic, work, and lifestyle-related factors. RESULTS Over the 12-month study period, the average direct healthcare expenditure per worker was US$505.00 and the average indirect cost because of sick leave was US$249.00 per worker. Direct costs were more than twice the indirect costs and both were higher in women. Body mass index was a determinant of direct costs and smoking was a determinant of indirect costs. CONCLUSIONS Obesity and smoking among workers in a Brazilian airline company were associated with increased health costs. Therefore, promoting a healthy diet, physical activity, and anti-tobacco campaigns are important targets for health promotion in this study population.

Direct versus indirect effects of tropospheric humidity changes on the hydrologic cycle

International Nuclear Information System (INIS)

Sherwood, S C

2010-01-01

Abundant evidence indicates that tropospheric specific humidity increases in a warmer atmosphere, at rates roughly comparable to those at constant relative humidity. While the implications for the planetary energy budget and global warming are well recognized, it is the net atmospheric cooling (or surface heating) that controls the hydrologic cycle. Relative humidity influences this directly through gas-phase radiative transfer, and indirectly by affecting cloud cover (and its radiative effects) and convective heating. Simple calculations show that the two indirect impacts are larger than the direct impact by roughly one and two orders of magnitude respectively. Global or regional relative humidity changes could therefore have significant indirect impacts on energy and water cycles, especially by altering deep convection, even if they are too small to significantly affect global temperature. Studies of climate change should place greater emphasis on these indirect links, which may not be adequately represented in models.

Accuracy of five intraoral scanners compared to indirect digitalization.

Science.gov (United States)

Güth, Jan-Frederik; Runkel, Cornelius; Beuer, Florian; Stimmelmayr, Michael; Edelhoff, Daniel; Keul, Christine

2017-06-01

Direct and indirect digitalization offer two options for computer-aided design (CAD)/ computer-aided manufacturing (CAM)-generated restorations. The aim of this study was to evaluate the accuracy of different intraoral scanners and compare them to the process of indirect digitalization. A titanium testing model was directly digitized 12 times with each intraoral scanner: (1) CS 3500 (CS), (2) Zfx Intrascan (ZFX), (3) CEREC AC Bluecam (BLU), (4) CEREC AC Omnicam (OC) and (5) True Definition (TD). As control, 12 polyether impressions were taken and the referring plaster casts were digitized indirectly with the D-810 laboratory scanner (CON). The accuracy (trueness/precision) of the datasets was evaluated by an analysing software (Geomagic Qualify 12.1) using a "best fit alignment" of the datasets with a highly accurate reference dataset of the testing model, received from industrial computed tomography. Direct digitalization using the TD showed the significant highest overall "trueness", followed by CS. Both performed better than CON. BLU, ZFX and OC showed higher differences from the reference dataset than CON. Regarding the overall "precision", the CS 3500 intraoral scanner and the True Definition showed the best performance. CON, BLU and OC resulted in significantly higher precision than ZFX did. Within the limitations of this in vitro study, the accuracy of the ascertained datasets was dependent on the scanning system. The direct digitalization was not superior to indirect digitalization for all tested systems. Regarding the accuracy, all tested intraoral scanning technologies seem to be able to reproduce a single quadrant within clinical acceptable accuracy. However, differences were detected between the tested systems.

A Field-Based Technique for Teaching about Habitat Fragmentation and Edge Effects

Science.gov (United States)

Resler, Lynn M.; Kolivras, Korine N.

2009-01-01

This article presents a field technique that exposes students to the indirect effects of habitat fragmentation on plant distributions through studying edge effects. This assignment, suited for students in an introductory biogeography or resource geography class, increases students' knowledge of basic biogeographic concepts such as environmental…

Social intervention and risk reduction - indirect countermeasures

International Nuclear Information System (INIS)

Higgins, N.A.; Morrey, M.

1996-01-01

An indirect countermeasure (IC) is an action which is intended to mitigate detrimental effects experienced by individuals or the community after an accident. Indirect countermeasures (ICs) achieve this, both by averting radiation risks arising from the accident, but by removing or reducing other risks and sources of stress or harm to which the community may be subject. ICs naturally fall into two categories: social action ICs, which range from introducing compensation payments to providing information centres; and risk reducing ICs which mitigate risks to which the population might be exposed, such as radon. By including a consideration of ICs in an assessment of the optimal response, it is likely that a decision maker will become aware of a greater range of harms and benefits that might result from the application of a countermeasure. The decision maker will then be in a better position to judge the appropriateness of any action. (author)

[Estimation on the indirect economic burden of disease-related premature deaths in China, 2012].

Science.gov (United States)

Yang, Juan; Feng, Luzhao; Zheng, Yaming; Yu, Hongjie

2014-11-01

To estimate the indirect economic burden of disease-related premature deaths in China, 2012. Both human capital approach and friction cost methods were used to compute the indirect economic burden of premature deaths from the following sources: mortality from the national disease surveillance system in 2012, average annual income per capita from the China Statistic Yearbook in 2012, population size from the 2010 China census, and life expectancy in China from the World Health Organization life table. Data from the Human Capital Approach Estimates showed that the indirect economic burden of premature deaths in China was 425.1 billion in 2012, accounting for 8‰ of the GDP. The indirect economic burden of chronic non-communicable diseases associated premature deaths was accounted for the highest proportion(67.1%, 295.4 billion), followed by those of injuries related premature deaths (25.6% , 108.9 billion), infectious diseases, maternal and infants diseases, and malnutrition related deaths (6.4% , 26.9 billion). The top five premature deaths that cause the indirect economic burden were malignancy, cardiovascular diseases, unintentional injuries, intentional injuries, and diseases of the respiratory system. The indirect economic burden of premature deaths mainly occurred in the population of 20-59 year-olds. Under the Friction Cost method, the estimates appeared to be 0.11%-3.49% of the total human capital approach estimates. Premature death caused heavy indirect economic burden in China. Chronic non-communicable diseases and injuries seemed to incur the major disease burden. The indirect economic burden of premature deaths mainly occurred in the working age group.

Manifestations and intensity of indirect self-destructiveness in patients with psoriasis vulgaris

Directory of Open Access Journals (Sweden)

Wojciech Bienias

2016-07-01

Full Text Available Introduction: Psoriasis is a chronic systemic disease which often significantly reduces the quality of life in extreme situations can provide to severe depression and even suicide. Indirect self-destructiveness is a generalized trend of behavior consisting of taking steps to increase the likelihood of negative and reduce the likelihood of positive consequences for the entity within a general manifestations such as transgression of norms and risk, addictions, poor health maintenance, personal and social neglect, lack of planfulness, helplessness and passiveness. Polish and world literature has no publications on indirect self-destructiveness in psoriasis nor in any skin diseases. The main aim of this study was to investigate the intensity and symptoms of indirect self-destructiveness in population of patients with psoriasis vulgaris Material and methods: The material consisted of 82 patients with psoriasis vulgaris hospitalized in the Department of Dermatology, Pediatric Dermatology and Oncology in 2013-2014. For the achievement of the objectives of the research socio-demographic questionnaire (own authorship and Indirect Chronic Self-Destructiveness Scale by Kelley in Polish adaptation of Suchańska (version for men and women – each containing 52 issues was used. Results: The results showed that in a population of people with psoriasis overall severity of indirect self-destructiveness was in the lower range of the average results. The dominant class of indirect self-destructiveness was helplessness and passivity that preceded the poor health maintenance and lack of planning. Conclusions: The results will enrich the existing knowledge about the harmful conduct of psoriasis and a better approach to the patient.

Natural resource validation: A primer on concepts and techniques

Energy Technology Data Exchange (ETDEWEB)

Ulibarri, C.A.; Wellman, K.F.

1997-07-01

Natural resource valuation has always had a fundamental role in the practice of cost-benefit analysis of health, safety, and environmental issues. The authors provide an objective overview of resource valuation techniques and describe their potential role in environmental restoration/waste management (ER/WM) activities at federal facilities. This handbook considers five general classes of valuation techniques: (1) market-based techniques, which rely on historical information on market prices and transactions to determine resource values; (2) nonmarket techniques that rely on indirect estimates of resource values; (3) nonmarket techniques that are based on direct estimates of resource values; (4) cross-cutting valuation techniques, which combine elements of one or more of these methods; and (5) ecological valuation techniques used in the emerging field of ecological economics. The various valuation techniques under consideration are described by highlighting their applicability in environmental management and regulation. The handbook also addresses key unresolved issues in the application of valuation techniques generally, including discounting future values, incorporating environmental equity concerns, and concerns over the uncertainties in the measurement of natural resource values and environmental risk.

Natural resource valuation: A primer on concepts and techniques

International Nuclear Information System (INIS)

Ulibarri, C.A.; Wellman, K.F.

1997-07-01

Natural resource valuation has always had a fundamental role in the practice of cost-benefit analysis of health, safety, and environmental issues. The authors provide an objective overview of resource valuation techniques and describe their potential role in environmental restoration/waste management (ER/WM) activities at federal facilities. This handbook considers five general classes of valuation techniques: (1) market-based techniques, which rely on historical information on market prices and transactions to determine resource values; (2) nonmarket techniques that rely on indirect estimates of resource values; (3) nonmarket techniques that are based on direct estimates of resource values; (4) cross-cutting valuation techniques, which combine elements of one or more of these methods; and (5) ecological valuation techniques used in the emerging field of ecological economics. The various valuation techniques under consideration are described by highlighting their applicability in environmental management and regulation. The handbook also addresses key unresolved issues in the application of valuation techniques generally, including discounting future values, incorporating environmental equity concerns, and concerns over the uncertainties in the measurement of natural resource values and environmental risk

How to Prepare an Indirect Cost Rate Proposal for a Non-profit Organization

Science.gov (United States)

The indirect cost rate proposal is the documentation prepared by a grantee organization, in accordance with applicable federal cost principles, to substantiate its claim for the reimbursement of indirect costs.

Shear bond strength of indirect composite material to monolithic zirconia.

Science.gov (United States)

Sari, Fatih; Secilmis, Asli; Simsek, Irfan; Ozsevik, Semih

2016-08-01

This study aimed to evaluate the effect of surface treatments on bond strength of indirect composite material (Tescera Indirect Composite System) to monolithic zirconia (inCoris TZI). Partially stabilized monolithic zirconia blocks were cut into with 2.0 mm thickness. Sintered zirconia specimens were divided into different surface treatment groups: no treatment (control), sandblasting, glaze layer & hydrofluoric acid application, and sandblasting + glaze layer & hydrofluoric acid application. The indirect composite material was applied to the surface of the monolithic zirconia specimens. Shear bond strength value of each specimen was evaluated after thermocycling. The fractured surface of each specimen was examined with a stereomicroscope and a scanning electron microscope to assess the failure types. The data were analyzed using one-way analysis of variance (ANOVA) and Tukey LSD tests (α=.05). Bond strength was significantly lower in untreated specimens than in sandblasted specimens (Pcomposite material and monolithic zirconia.

Water augmented indirectly-fired gas turbine systems and method

Science.gov (United States)

Bechtel, Thomas F.; Parsons, Jr., Edward J.

1992-01-01

An indirectly-fired gas turbine system utilizing water augmentation for increasing the net efficiency and power output of the system is described. Water injected into the compressor discharge stream evaporatively cools the air to provide a higher driving temperature difference across a high temperature air heater which is used to indirectly heat the water-containing air to a turbine inlet temperature of greater than about 1,000.degree. C. By providing a lower air heater hot side outlet temperature, heat rejection in the air heater is reduced to increase the heat recovery in the air heater and thereby increase the overall cycle efficiency.

Testing indirect effect of consumer attitudes toward a product

DEFF Research Database (Denmark)

Hrubá, Renata; Sudzina, Frantisek

2016-01-01

a questionnaire in 2010-2011. The model is estimated using probit analysis to predict relationship between producer and consumer in decision-making when buying a new type of cheese and to examine consumer attitudes toward food origins and nutrient food security. It can be concluded that the indirect effect (e...... and on the indirect and direct effects of the perception of information through information behavior and the use of the model ordered. It is proposed that consumer levels of product familiarity of attributes affects behavior. Consumer attitudes towards agri-food products and behaviour were analyzed through...

Simple, direct drug susceptibility testing technique for diagnosis of drug-resistant tuberculosis in resource-poor settings.

Science.gov (United States)

Kim, C-K; Joo, Y-T; Lee, E P; Park, Y K; Kim, H-J; Kim, S J

2013-09-01

The Korean Institute of Tuberculosis, Seoul, Republic of Korea. To develop a simple, direct drug susceptibility testing (DST) technique using Kudoh-modified Ogawa (KMO) medium. The critical concentrations of isoniazid (INH), rifampicin (RMP), kanamycin (KM) and ofloxacin (OFX) for KMO medium were calibrated by comparing the minimal inhibitory concentrations (MICs) against clinical isolates of Mycobacterium tuberculosis on KMO with those on Löwenstein-Jensen (LJ). The performance of the direct KMO DST technique was evaluated on 186 smear-positive sputum specimens and compared with indirect LJ DST. Agreement of MICs on direct vs. indirect DST was high for INH, RMP and OFX. KM MICs on KMO were ∼10 g/ml higher than those on LJ. The critical concentrations of INH, RMP, OFX and KM for KMO were therefore set at 0.2, 40.0, 2.0, and 40.0 g/ml. The evaluation of direct DST of smear-positive sputum specimens showed 100% agreement with indirect LJ DST for INH and RMP. However, the respective susceptible and resistant predictive values were 98.8% and 100% for OFX, and 100% and 80% for KM. Direct DST using KMO is useful, with clear advantages of a shorter turnaround time, procedural simplicity and low cost compared to indirect DST. It may be most indicated in resource-poor settings for programmatic management of drug-resistant tuberculosis.

Sibling Relation, Ethnic Prejudice, Direct and Indirect Contact: There is a Connection?

Directory of Open Access Journals (Sweden)

Sara Alfieri

2015-11-01

Full Text Available The literature on the socialisation of prejudice has concentrated on “vertical” processes (from parents to children, ignoring siblings’ contribution. This work aims to investigate the effect of contact (direct or indirect with the outgroup that young people experience a directly or b indirectly through older or younger siblings’ friendships. Our hypotheses are a that young people with friends in the outgroup will report lower prejudice levels (direct contact, as will young people who have older or younger siblings with friends in the outgroup (indirect contact; b that other forms of contact such as having classmates/coworkers, neighbours, or employees are not effective in reducing either direct or indirect prejudice. 88 sibling dyads were administered the blatant and subtle prejudice questionnaire (Pettigrew & Meertens, 1995 and some ad hoc items aimed at investigating the typology of the contact experienced. The analysis of mixed ANOVA reveals that the first hypothesis was partially confirmed in that prejudice (subtle for the younger sibling and blatant for the older one decreases in a statistically significant way only when there is the co-presence of direct and indirect contact. The second hypothesis is fully confirmed as no statistically significant differences emerged between the groups.

Sibling Relation, Ethnic Prejudice, Direct and Indirect Contact: There is a Connection?

Science.gov (United States)

Alfieri, Sara; Marta, Elena

2015-01-01

The literature on the socialisation of prejudice has concentrated on “vertical” processes (from parents to children), ignoring siblings’ contribution. This work aims to investigate the effect of contact (direct or indirect) with the outgroup that young people experience a) directly or b) indirectly through older or younger siblings’ friendships. Our hypotheses are a) that young people with friends in the outgroup will report lower prejudice levels (direct contact), as will young people who have older or younger siblings with friends in the outgroup (indirect contact); b) that other forms of contact such as having classmates/coworkers, neighbours, or employees are not effective in reducing either direct or indirect prejudice. 88 sibling dyads were administered the blatant and subtle prejudice questionnaire (Pettigrew & Meertens, 1995) and some ad hoc items aimed at investigating the typology of the contact experienced. The analysis of mixed ANOVA reveals that the first hypothesis was partially confirmed in that prejudice (subtle for the younger sibling and blatant for the older one) decreases in a statistically significant way only when there is the co-presence of direct and indirect contact. The second hypothesis is fully confirmed as no statistically significant differences emerged between the groups. PMID:27247684