"Indirect Network Effects and the Product Cycle: Video Games in the U.S., 1994-2002"

OpenAIRE

Matthew T. Clements; Hiroshi Ohashi

2004-01-01

This paper examines the importance of indirect network effects in the U.S. video game market between 1994 and 2002. The diffusion of game systems is analyzed by the interaction between console adoption decisions and software supply decisions. Estimation results suggest that introductory pricing is an effective practice at the beginning of the product cycle, and expanding software variety becomes more effective later. The paper also finds a degree of inertia in the software market that does no...

Indirect-fired gas turbine bottomed with fuel cell

Science.gov (United States)

Micheli, P.L.; Williams, M.C.; Parsons, E.L.

1995-09-12

An indirect-heated gas turbine cycle is bottomed with a fuel cell cycle with the heated air discharged from the gas turbine being directly utilized at the cathode of the fuel cell for the electricity-producing electrochemical reaction occurring within the fuel cell. The hot cathode recycle gases provide a substantial portion of the heat required for the indirect heating of the compressed air used in the gas turbine cycle. A separate combustor provides the balance of the heat needed for the indirect heating of the compressed air used in the gas turbine cycle. Hot gases from the fuel cell are used in the combustor to reduce both the fuel requirements of the combustor and the NOx emissions therefrom. Residual heat remaining in the air-heating gases after completing the heating thereof is used in a steam turbine cycle or in an absorption refrigeration cycle. Some of the hot gases from the cathode can be diverted from the air-heating function and used in the absorption refrigeration cycle or in the steam cycle for steam generating purposes. 1 fig.

Marta Cycles'i jääkideta disain / Marta Moorats ; intervjueerinud Aljona Sokolovskaja

Index Scriptorium Estoniae

Moorats, Marta

2013-01-01

Disainkäsitöö pop-up näitus Kawe Plaza ruumides (Tallinn, Pärnu mnt. 15). Oma töid eksponeerib ka Marta Moorats, disainerinimega Marta Cycles. Lähemalt tema langevarjukangast rõivakollektsioonist, mis põhineb jääkideta disainil

A Framework for Modelling Indirect Land Use Changes in Life Cycle Assessment

DEFF Research Database (Denmark)

Schmidt, Jannick Højrup; Weidema, Bo Pedersen; Brandão, Miguel

2015-01-01

Around 9% of global CO2 emissions originate from land use changes. Often, these emissions are not appropriately addressed in Life Cycle Assessment. The link between demand for crops in one region and impacts in other regions is referred to here as indirect land use change (iLUC) and includes...... demand for land and land use changes is established through markets for land's production capacity. The iLUC model presented is generally applicable to all land use types, crops and regions of the world in typical LCA decision-making contexts focusing on the long-term effects of small-scale changes...... deforestation, intensification and reduced consumption. Existing models for iLUC tend to ignore intensification and reduced consumption, they most often operate with arbitrary amortisation periods to allocate deforestation emissions over time, and the causal link between land occupation and deforestation...

Stress and estrous cycle affect strategy but not performance of female C57BL/6J mice

NARCIS (Netherlands)

ter Horst, J.P.; Kentrop, J.; de Kloet, E.R.; Oitzl, M.S.

2013-01-01

Stress induces a switch in learning strategies of male C57BL/6J mice from predominantly spatial to more stimulus-response learning. To study generalization of these findings over sex, we investigated female C57BL/6J mice at three phases of the estrous cycle under non stress and acute (10 min)

A nuclear gas turbine perspective: The indirect cycle (IDC) offers a practical solution

International Nuclear Information System (INIS)

McDonald, C.F.

1996-01-01

The current generation of nuclear power plants are based on light water reactors and steam cycle power conversion systems. This coupling yields a power plant efficiency of less than 30% when dry-cooled. By utilizing a higher temperature heat source, and a more efficient prime-mover, the next generation of nuclear power plants have the potential for an efficiency of close to 50%, with attendant fuel savings and reduced heat rejection to the environment. The nuclear closed Brayton cycle (NCBC) gas turbine plant involves the coupling of a high temperature reactor (HTR) and a high efficiency helium gas turbine. Studies over many years have shown the merits of an indirect cycle (IDC) approach in which an intermediate heat exchanger is used to transfer the reactor thermal energy to the prime-mover. The major advantages of this include the following: (1) multipurpose nuclear heat source; (2) gas turbine operation in a clean non-nuclear environment; (3) power conversion system simplicity; and (4) maximum utilization of existing technology. An additional factor, which may dominate the above is that the IDC approach is in concert with the only active gas-cooled reactor program remaining in the world, namely a high temperature test reactor (HTTR) under construction in Japan, the culmination of which will be the demonstration of a viable high temperature nuclear heat source. The major theme of this paper is that the IDC nuclear gas turbine offers a practical NCBC power plant concept for operation in the second or third decades of the 21st century

Thermodynamic modelling and efficiency analysis of a class of real indirectly fired gas turbine cycles

Directory of Open Access Journals (Sweden)

Ma Zheshu

2009-01-01

Full Text Available Indirectly or externally-fired gas-turbines (IFGT or EFGT are novel technology under development for small and medium scale combined power and heat supplies in combination with micro gas turbine technologies mainly for the utilization of the waste heat from the turbine in a recuperative process and the possibility of burning biomass or 'dirty' fuel by employing a high temperature heat exchanger to avoid the combustion gases passing through the turbine. In this paper, by assuming that all fluid friction losses in the compressor and turbine are quantified by a corresponding isentropic efficiency and all global irreversibilities in the high temperature heat exchanger are taken into account by an effective efficiency, a one dimensional model including power output and cycle efficiency formulation is derived for a class of real IFGT cycles. To illustrate and analyze the effect of operational parameters on IFGT efficiency, detailed numerical analysis and figures are produced. The results summarized by figures show that IFGT cycles are most efficient under low compression ratio ranges (3.0-6.0 and fit for low power output circumstances integrating with micro gas turbine technology. The model derived can be used to analyze and forecast performance of real IFGT configurations.

Performance analysis of a Miller cycle engine by an indirect analysis method with sparking and knock in consideration

International Nuclear Information System (INIS)

Wang, Yuanfeng; Zu, Bingfeng; Xu, Yuliang; Wang, Zhen; Liu, Jie

2016-01-01

Highlights: • A quasi-dimensional model was adopted to study Miller cycle engine’s performance. • A new indirect performance analysis method was proposed. • The definition of effective compression ratio was modified. • The modified effective compression ratio takes the trapped mixture mass in account. • The factors limiting the fuel economy in Miller cycle engine were found out. - Abstract: In this paper, a full-factorial design of experiment was applied to thoroughly investigate the effects of compression ratio, intake valve closing retardation angle, and engine speed on the fuel consumption performance and power performance of the Miller cycle engine based on a quasi-dimensional simulation model. A new indirect analysis method based on formula derivation and main effect analysis was proposed to simplify the complex relationship between the design factors and the performance parameters. The definition of effective compression ratio was modified to take account of the actual mass of mixture trapped in the cylinder. The results show that the distributions of brake mean effective pressure and brake specific fuel consumption can be regarded as the re-organization results from the distributions of volumetric efficiency and indicated efficiency. The intake valve closing retardation angle has a strong negative correlation with volumetric efficiency. The modified effective compression ratio is the approximate product of the compression ratio and the volumetric efficiency, and makes obvious effects on the distribution of the indicated efficiency. Therefore the combustion process is co-evolved with the intake process in a Miller cycle engine. The further improvement of brake specific fuel consumption is mainly limited by four factors, i.e., the back flow loss, the exergy loss, the incomplete expansion loss, and the combustion loss. The improvement of fuel consumption performance is at a cost of power performance, and the trade-off between the both essentially

Avian leukosis virus subgroup J promotes cell proliferation and cell cycle progression through miR-221 by targeting CDKN1B.

Science.gov (United States)

Ren, Chaoqi; Yu, Mengmeng; Zhang, Yao; Fan, Minghui; Chang, Fangfang; Xing, Lixiao; Liu, Yongzhen; Wang, Yongqiang; Qi, Xiaole; Liu, Changjun; Zhang, Yanping; Cui, Hongyu; Li, Kai; Gao, Li; Pan, Qing; Wang, Xiaomei; Gao, Yulong

2018-04-23

Avian leukosis virus subgroup J (ALV-J), a highly oncogenic retrovirus, causes leukemia-like proliferative diseases in chickens. microRNAs post-transcriptionally suppress targets and are involved in the development of various tumors. We previously showed that miR-221 is upregulated in ALV-J-induced tumors. In this study, we analyzed the possible function of miR-221 in ALV-J tumorigenesis. The target validation system showed that CDKN1B is a target of miR-221 and is downregulated in ALV-J infection. As CDKN1B arrests the cell cycle and regulates its progression, we analyzed the proliferation of ALV-J-infected DF-1 cells. ALV-J-infection-induced DF1 cell derepression of G1/S transition and overproliferation required high miR-221 expression followed by CDKN1B downregulation. Cell cycle pathway analysis showed that ALV-J infection induced DF-1 cell overproliferation via the CDKN1B-CDK2/CDK6 pathway. Thus, miR-221 may play an important role in ALV-J-induced aggressive growth of DF-1 cells; these findings have expanded our insights into the mechanism underlying ALV-J infection and tumorigenesis. Copyright © 2018 Elsevier Inc. All rights reserved.

Theoretical and experimental evaluation of an indirect-fired GAX cycle cooling system

Energy Technology Data Exchange (ETDEWEB)

Gomez, V.H.; Vidal, A. [Posgrado en Ingenieria, Energia, Universidad Nacional Autonoma de Mexico, Privada Xochicalco S/N, Apdo. Postal 34, 62580 Temixco Morelos (Mexico); Best, R.; Garcia-Valladares, O. [Centro de Investigacion en Energia, Universidad Nacional Autonoma de Mexico, Privada Xochicalco S/N, Apdo. Postal 34, 62580 Temixco Morelos (Mexico); Velazquez, N. [Instituto de Ingenieria, Universidad Autonoma de Baja California, Calle de la Normal S/N, Insurgentes Este, 21280 Mexicali, BC (Mexico)

2008-06-15

A theoretical and experimental evaluation of an indirect-fired GAX-Prototype Cooling System (GAX-PCS), using ammonia-water as the working fluid, is presented. The GAX-PCS was designed for a cooling capacity of 10.6 kW (3 tons). A simulation model was developed, calibrated and validated with experimental values in order to predict the performance of the system outside the design parameters. Experimental results were obtained using thermal oil, at temperatures from 180 to 195 C, as heating source. An internal heat recovery in the system of {proportional_to}55% with respect to the total heat supplied in the generator was obtained. Also the performance of the GAX absorption system, integrated to a micro gas turbine (MGT) as a cogeneration system was simulated. Overall efficiencies for the cogeneration system from 29% to 49% were obtained for cooling loads from 5 kW to 20 kW, respectively. With the theoretical and experimental study of the proposed cycle, it is concluded that the GAX-PCS presents potential to compete technically in the Mexican air conditioning market. (author)

A study of a high temperature nuclear power plant incorporating a non-integrated indirect cycle gas turbine

International Nuclear Information System (INIS)

Sarlos, G.; Helbling, W.; Zollinger, E.; Gregory, N.; Luchsinger, H.

1982-04-01

In connection with the HHT-project, the Swiss Federal Institute for Reactor Research has performed a study of a 1640-MWth HTR-plant incorporating a non-integrated indirect cycle gas turbine with two-stage intercooling, as a possibility of simplifying and reducing the cost of the HHT-demonstration plant. In this paper, the plant design is described and compared with the HHT-demonstration plant (a CCGT integrated plant with single stage intercooling). Also included is an evaluation of the various advantages and disadvantages of this design together with the presentation of some of the sensitivity results. (Auth.)

Effect of the mutations recB21, recD1013 and recJ284 of Escherichia coli on the indirect recombinogenesis of the lambda bacteriophage

International Nuclear Information System (INIS)

Alcantara D, D.

1994-01-01

The protein RecBCD of Escherichia coli is of those more important, so much in the genetic recombination as in the repair of the genetic damage. Due to their importance in the genetic recombination in general and to that the enzyme is not completely inactivated in cells infected with lambda, it was decided to prove their participation in the indirect viral recombinogenesis. The obtained data indicated that RecBCD plays a central role in the indirect recombinogenesis of lambda, since in the mutants recB21 and recD1013 the response is not presented or it decreases drastically. Also it was proven that RecBCD cannot be substituted by the double band DNA exonuclease, coded by the recJ gene. (Author)

Direct and indirect measures of speech articulator motions using low power EM sensors

International Nuclear Information System (INIS)

Barnes, T; Burnett, G; Gable, T; Holzrichter, J F; Ng, L

1999-01-01

Low power Electromagnetic (EM) Wave sensors can measure general properties of human speech articulator motions, as speech is produced. See Holzrichter, Burnett, Ng, and Lea, J.Acoust.Soc.Am. 103 (1) 622 (1998). Experiments have demonstrated extremely accurate pitch measurements ( and lt; 1 Hz per pitch cycle) and accurate onset of voiced speech. Recent measurements of pressure-induced tracheal motions enable very good spectra and amplitude estimates of a voiced excitation function. The use of the measured excitation functions and pitch synchronous processing enable the determination of each pitch cycle of an accurate transfer function and, indirectly, of the corresponding articulator motions. In addition, direct measurements have been made of EM wave reflections from articulator interfaces, including jaw, tongue, and palate, simultaneously with acoustic and glottal open/close signals. While several types of EM sensors are suitable for speech articulator measurements, the homodyne sensor has been found to provide good spatial and temporal resolution for several applications

The crystal structure of the human co-chaperone P58(IPK.

Directory of Open Access Journals (Sweden)

Maria Svärd

Full Text Available P58(IPK is one of the endoplasmic reticulum- (ER- localised DnaJ (ERdj proteins which interact with the chaperone BiP, the mammalian ER ortholog of Hsp70, and are thought to contribute to the specificity and regulation of its diverse functions. P58(IPK, expression of which is upregulated in response to ER stress, has been suggested to act as a co-chaperone, binding un- or misfolded proteins and delivering them to BiP. In order to give further insights into the functions of P58(IPK, and the regulation of BiP by ERdj proteins, we have determined the crystal structure of human P58(IPK to 3.0 Å resolution using a combination of molecular replacement and single wavelength anomalous diffraction. The structure shows the human P58(IPK monomer to have a very elongated overall shape. In addition to the conserved J domain, P58(IPK contains nine N-terminal tetratricopeptide repeat motifs, divided into three subdomains of three motifs each. The J domain is attached to the C-terminal end via a flexible linker, and the structure shows the conserved Hsp70-binding histidine-proline-aspartate (HPD motif to be situated on the very edge of the elongated protein, 100 Å from the putative binding site for unfolded protein substrates. The residues that comprise the surface surrounding the HPD motif are highly conserved in P58(IPK from other organisms but more varied between the human ERdj proteins, supporting the view that their regulation of different BiP functions is facilitated by differences in BiP-binding.

Motives and algebraic cycles a celebration in honour of Spencer J. Bloch

CERN Document Server

Jeu, Rob de; Lewis, James D

2009-01-01

Spencer J. Bloch has, and continues to have, a profound influence on the subject of Algebraic K-Theory, Cycles and Motives. This book, which is comprised of a number of independent research articles written by leading experts in the field, is dedicated in his honour, and gives a snapshot of the current and evolving nature of the subject. Some of the articles are written in an expository style, providing a perspective on the current state of the subject to those wishing to learn more about it. Others are more technical, representing new developments and making them especially interesting to res

Mapping the anatomy of social engineering attacks to the systems engineering life cycle

CSIR Research Space (South Africa)

Van de Merwe, J

2017-11-01

Full Text Available in Information and Communication Technology), pp. 266–279. doi: 10.1007/978-3-662-44208-1_22. Mouton, F. et al. (2015) ‘Necessity for ethics in social engineering research’, Computers & Security, 55, pp. 114–127. doi: http://dx.doi.org/10.1016/j.cose.2015... space. These include a context diagram, functional modelling, holistic requirements modelling, matrix diagrams, stakeholder maps and a viewpoint analysis. Keywords Bidirectional Communication, Indirect Communication, Mitnick's Attack Cycle, Social...

Discovery of Pulsations from the Pulsar J0205 6449 in SNR 3C 58 with the Fermi Gamma-Ray Space Telescope

Energy Technology Data Exchange (ETDEWEB)

Abdo, Aous A.; /Naval Research Lab, Wash., D.C.; Ackermann, M.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Ajello, Marco; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Atwood, William B.; /UC, Santa Cruz; Axelsson, M.; /Stockholm U., OKC /Stockholm U.; Baldini, L.; /INFN, Pisa; Ballet, J.; /DAPNIA, Saclay; Barbiellini, Guido; /INFN, Trieste /Trieste U.; Bastieri, Denis; /INFN, Padua /Padua U.; Baughman, B.M.; /Ohio State U.; Bechtol, K.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bellazzini, Ronaldo; /INFN, Pisa; Berenji, Bijan; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Blandford, Roger D.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bloom, Elliott D.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bonamente, E.; /INFN, Perugia /Perugia U.; Borgland, Anders W.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bouvier, A.; /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; Bregeon, J.; /INFN, Pisa; Brez, A.; /INFN, Pisa; Brigida, M.; /Bari U. /INFN, Bari /Ecole Polytechnique /Washington U., Seattle /Bari U. /INFN, Bari /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Columbia U. /IASF, Milan /IASF, Milan /DAPNIA, Saclay /INFN, Perugia /Perugia U. /NASA, Goddard /George Mason U. /Naval Research Lab, Wash., D.C. /NASA, Goddard /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /INFN, Perugia /Perugia U. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /LPCE, Orleans /Montpellier U. /Stockholm U., OKC /Royal Inst. Tech., Stockholm /Stockholm U. /Naval Research Lab, Wash., D.C. /INFN, Trieste /Bari U. /INFN, Bari /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /UC, Santa Cruz /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /CENBG, Gradignan /CENBG, Gradignan /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Manchester U. /Montpellier U. /Bari U. /INFN, Bari /Stanford U., HEPL /KIPAC, Menlo Park /Stanford U., Phys. Dept.; /more authors..

2011-12-01

We report the discovery of {gamma}-ray pulsations ({ge}0.1 GeV) from the young radio and X-ray pulsar PSR J0205 + 6449 located in the Galactic supernova remnant 3C 58. Data in the {gamma}-ray band were acquired by the Large Area Telescope aboard the Fermi Gamma-ray Space Telescope (formerly GLAST), while the radio rotational ephemeris used to fold {gamma}-rays was obtained using both the Green Bank Telescope and the Lovell telescope at Jodrell Bank. The light curve consists of two peaks separated by 0.49 {+-} 0.01 {+-} 0.01 cycles which are aligned with the X-ray peaks. The first {gamma}-ray peak trails the radio pulse by 0.08 {+-} 0.01 {+-} 0.01, while its amplitude decreases with increasing energy as for the other {gamma}-ray pulsars. Spectral analysis of the pulsed {gamma}-ray emission suggests a simple power law of index -2.1 {+-} 0.1 {+-} 0.2 with an exponential cutoff at 3.0{sub -0.7}{sup +1.1} {+-} 0.4 GeV. The first uncertainty is statistical and the second is systematic. The integral {gamma}-ray photon flux above 0.1 GeV is (13.7 {+-} 1.4 {+-} 3.0) x 10{sup -8} cm{sup -2} s{sup -1}, which implies for a distance of 3.2 kpc and assuming a broad fan-like beam a luminosity of 8.3 x 10{sup 34} erg s{sup -1} and an efficiency {eta} of 0.3%. Finally, we report a 95% upper limit on the flux of 1.7 x 10{sup -8} cm{sup -2} s{sup -1} for off-pulse emission from the object.

Discovery of Pulsations from the Pulsar J0205 6449 in SNR 3C 58 with the Fermi Gamma-Ray Space Telescope

International Nuclear Information System (INIS)

Abdo, Aous A.; Ackermann, M.; Ajello, Marco; Atwood, William B.; Axelsson, M.; Baldini, L.; Ballet, J.; Barbiellini, Guido; Bastieri, Denis; Baughman, B.M.; Bechtol, K.; Bellazzini, Ronaldo; Berenji, Bijan; Blandford, Roger D.; Bloom, Elliott D.; Bonamente, E.; Borgland, Anders W.; Bouvier, A.; Bregeon, J.; Brez, A.; Brigida, M.

2009-01-01

We report the discovery of γ-ray pulsations ((ge)0.1 GeV) from the young radio and X-ray pulsar PSR J0205 + 6449 located in the Galactic supernova remnant 3C 58. Data in the γ-ray band were acquired by the Large Area Telescope aboard the Fermi Gamma-ray Space Telescope (formerly GLAST), while the radio rotational ephemeris used to fold γ-rays was obtained using both the Green Bank Telescope and the Lovell telescope at Jodrell Bank. The light curve consists of two peaks separated by 0.49 ± 0.01 ± 0.01 cycles which are aligned with the X-ray peaks. The first γ-ray peak trails the radio pulse by 0.08 ± 0.01 ± 0.01, while its amplitude decreases with increasing energy as for the other γ-ray pulsars. Spectral analysis of the pulsed γ-ray emission suggests a simple power law of index -2.1 ± 0.1 ± 0.2 with an exponential cutoff at 3.0 -0.7 +1.1 ± 0.4 GeV. The first uncertainty is statistical and the second is systematic. The integral γ-ray photon flux above 0.1 GeV is (13.7 ± 1.4 ± 3.0) x 10 -8 cm -2 s -1 , which implies for a distance of 3.2 kpc and assuming a broad fan-like beam a luminosity of 8.3 x 10 34 erg s -1 and an efficiency η of 0.3%. Finally, we report a 95% upper limit on the flux of 1.7 x 10 -8 cm -2 s -1 for off-pulse emission from the object.

DISCOVERY OF PULSATIONS FROM THE PULSAR J0205+6449 IN SNR 3C 58 WITH THE FERMI GAMMA-RAY SPACE TELESCOPE

International Nuclear Information System (INIS)

Abdo, A. A.; Ackermann, M.; Ajello, M.; Bechtol, K.; Berenji, B.; Blandford, R. D.; Bloom, E. D.; Borgland, A. W.; Bouvier, A.; Atwood, W. B.; Axelsson, M.; Baldini, L.; Bellazzini, R.; Bregeon, J.; Brez, A.; Ballet, J.; Barbiellini, G.; Bastieri, D.; Baughman, B. M.; Bonamente, E.

2009-01-01

We report the discovery of γ-ray pulsations (≥0.1 GeV) from the young radio and X-ray pulsar PSR J0205 + 6449 located in the Galactic supernova remnant 3C 58. Data in the γ-ray band were acquired by the Large Area Telescope aboard the Fermi Gamma-ray Space Telescope (formerly GLAST), while the radio rotational ephemeris used to fold γ-rays was obtained using both the Green Bank Telescope and the Lovell telescope at Jodrell Bank. The light curve consists of two peaks separated by 0.49 ± 0.01 ± 0.01 cycles which are aligned with the X-ray peaks. The first γ-ray peak trails the radio pulse by 0.08 ± 0.01 ± 0.01, while its amplitude decreases with increasing energy as for the other γ-ray pulsars. Spectral analysis of the pulsed γ-ray emission suggests a simple power law of index -2.1 ± 0.1 ± 0.2 with an exponential cutoff at 3.0 +1.1 -0.7 ± 0.4 GeV. The first uncertainty is statistical and the second is systematic. The integral γ-ray photon flux above 0.1 GeV is (13.7 ± 1.4 ± 3.0) x 10 -8 cm -2 s -1 , which implies for a distance of 3.2 kpc and assuming a broad fan-like beam a luminosity of 8.3 x 10 34 erg s -1 and an efficiency η of 0.3%. Finally, we report a 95% upper limit on the flux of 1.7 x 10 -8 cm -2 s -1 for off-pulse emission from the object.

N2-fixing red alder indirectly accelerates ecosystem nitrogen cycling

Science.gov (United States)

Perakis, Steven S.; Matkins, Joselin J.; Hibbs, David E.

2012-01-01

Symbiotic N2-fixing tree species can accelerate ecosystem N dynamics through decomposition via direct pathways by producing readily decomposed leaf litter and increasing N supply to decomposers, as well as via indirect pathways by increasing tissue and detrital N in non-fixing vegetation. To evaluate the relative importance of these pathways, we compared three-year decomposition and N dynamics of N2-fixing red alder leaf litter (2.34 %N) to both low-N (0.68 %N) and high-N (1.21 %N) litter of non-fixing Douglas-fir, and decomposed each litter source in four forests dominated by either red alder or Douglas-fir. We also used experimental N fertilization of decomposition plots to assess elevated N availability as a potential mechanism of N2-fixer effects on litter mass loss and N dynamics. Direct effects of N2-fixing red alder on decomposition occurred primarily as faster N release from red alder than Douglas-fir litter, but direct increases in N supply to decomposers via fertilization did not stimulate decomposition of any litter. Fixed N indirectly influenced detrital dynamics by increasing Douglas-fir tissue and litter N concentrations, which accelerated litter N release without accelerating mass loss. By increasing soil N, tissue N, and the rate of N release from litter of non-fixers, we conclude that N2-fixing vegetation can indirectly foster plant-soil feedbacks that contribute to the persistence of elevated N availability in terrestrial ecosystems.

Neutron-capture Cross Sections from Indirect Measurements

Energy Technology Data Exchange (ETDEWEB)

Escher, J E; Burke, J T; Dietrich, F S; Ressler, J J; Scielzo, N D; Thompson, I J

2011-10-18

Cross sections for compound-nuclear reactions play an important role in models of astrophysical environments and simulations of the nuclear fuel cycle. Providing reliable cross section data remains a formidable task, and direct measurements have to be complemented by theoretical predictions and indirect methods. The surrogate nuclear reactions method provides an indirect approach for determining cross sections for reactions on unstable isotopes, which are difficult or impossible to measure otherwise. Current implementations of the method provide useful cross sections for (n,f) reactions, but need to be improved upon for applications to capture reactions.

Global indirect aerosol effects: a review

Directory of Open Access Journals (Sweden)

U. Lohmann

2005-01-01

Full Text Available Aerosols affect the climate system by changing cloud characteristics in many ways. They act as cloud condensation and ice nuclei, they may inhibit freezing and they could have an influence on the hydrological cycle. While the cloud albedo enhancement (Twomey effect of warm clouds received most attention so far and traditionally is the only indirect aerosol forcing considered in transient climate simulations, here we discuss the multitude of effects. Different approaches how the climatic implications of these aerosol effects can be estimated globally as well as improvements that are needed in global climate models in order to better represent indirect aerosol effects are discussed in this paper.

Diverting indirect subsidies from the nuclear industry to the photovoltaic industry: Energy and financial returns

International Nuclear Information System (INIS)

Zelenika-Zovko, I.; Pearce, J.M.

2011-01-01

Nuclear power and solar photovoltaic energy conversion often compete for policy support that governs economic viability. This paper compares current subsidization of the nuclear industry with providing equivalent support to manufacturing photovoltaic modules. Current U.S. indirect nuclear insurance subsidies are reviewed and the power, energy and financial outcomes of this indirect subsidy are compared to equivalent amounts for indirect subsidies (loan guarantees) for photovoltaic manufacturing using a model that holds economic values constant for clarity. The preliminary analysis indicates that if only this one relatively ignored indirect subsidy for nuclear power was diverted to photovoltaic manufacturing, it would result in more installed power and more energy produced by mid-century. By 2110 cumulative electricity output of solar would provide an additional 48,600 TWh over nuclear worth $5.3 trillion. The results clearly show that not only does the indirect insurance liability subsidy play a significant factor for nuclear industry, but also how the transfer of such an indirect subsidy from the nuclear to photovoltaic industry would result in more energy over the life cycle of the technologies. - Highlights: → The indirect insurance liability subsidy has been quantified over the life cycle of the U.S. nuclear fleet. → It was found to play a significant factor in the economics of the nuclear industry. → A transfer of such an indirect subsidy from the nuclear to photovoltaic industry would result in significantly more energy over the life cycle of the technologies.

Neutron-capture cross sections from indirect measurements

Directory of Open Access Journals (Sweden)

Scielzo N.D.

2012-02-01

Full Text Available Cross sections for compound-nuclear reactions reactions play an important role in models of astrophysical environments and simulations of the nuclear fuel cycle. Providing reliable cross section data remains a formidable task, and direct measurements have to be complemented by theoretical predictions and indirect methods. The surrogate nuclear reactions method provides an indirect approach for determining cross sections for reactions on unstable isotopes, which are difficult or impossible to measure otherwise. Current implementations of the method provide useful cross sections for (n,f reactions, but need to be improved upon for applications to capture reactions.

Carbon Footprint of Inbound Tourism to Iceland: A Consumption-Based Life-Cycle Assessment including Direct and Indirect Emissions

Directory of Open Access Journals (Sweden)

Hannah Sharp

2016-11-01

Full Text Available The greenhouse gas (GHG emissions caused by tourism have been studied from several perspectives, but few studies exist that include all direct and indirect emissions, particularly those from aviation. In this study, an input/output-based hybrid life-cycle assessment (LCA method is developed to assess the consumption-based carbon footprint of the average tourist including direct and indirect emissions. The total inbound tourism-related GHG emissions are also calculated within a certain region. As a demonstration of the method, the full carbon footprint of an average tourist is assessed as well as the total GHG emissions induced by tourism to Iceland over the period of 2010–2015, with the presented approach applicable in other contexts as well. Iceland provides an interesting case due to three features: (1 the tourism sector in Iceland is the fastest-growing industry in the country with an annual growth rate of over 20% over the past five years; (2 almost all tourists arrive by air; and (3 the country has an almost emissions-free energy industry and an import-dominated economy, which emphasise the role of the indirect emissions. According to the assessment, the carbon footprint for the average tourist is 1.35 tons of CO2-eq, but ranges from 1.1 to 3.2 tons of CO2-eq depending on the distance travelled by air. Furthermore, this footprint is increasing due to the rise in average flight distances travelled to reach the country. The total GHG emissions caused by tourism in Iceland have tripled from approximately 600,000 tons of CO2-eq in 2010 to 1,800,000 tons in 2015. Aviation accounts for 50%–82% of this impact (depending on the flight distance underlining the importance of air travel, especially as tourism-related aviation is forecasted to grow significantly in the near future. From a method perspective, the carbon footprinting application presented in the study would seem to provide an efficient way to study both the direct and indirect

Effect of task familiarisation on distribution of energy during a 2000 m cycling time trial.

Science.gov (United States)

Corbett, J; Barwood, M J; Parkhouse, K

2009-10-01

To investigate the effect of task familiarisation on the spontaneous pattern of energy expenditure during a series of 2000 m cycling time trials (TTs). Nine trained males completed three 2000 m TTs on a Velotron cycling ergometer. To examine pacing strategy, the data were assigned to 250 m "bins," with the pattern of aerobic and anaerobic energy expenditure calculated from total work accomplished and gas-exchange data. There were no significant differences between trials in performance times (191.4 (SD 4.3), 189.4 (4.6), 190.1 (5.6) s), total aerobic (58.3 (2.7), 58.4 (3.1), 58.0 (3.4) kJ) and total anaerobic energy expenditure (16.4 (3.3), 17.3 (2.8), 16.5 (3.1) kJ). Pacing strategy in the second and third TT differed from the first TT in that a lower power output was adopted during the first 500 m, enabling a higher power output during the final 750 m of the TT. This adjustment in the pattern of energy expenditure was mediated by an alteration in the pattern of anaerobic energy expenditure, which paralleled changes in total energy expenditure. Furthermore, participants retained an anaerobic energy "reserve" enabling an end-spurt during the second and third trials. Small modifications to the pacing strategy are made following a single bout of exercise, primarily by altering the rate of anaerobic energy expenditure. This may have served to prevent critical metabolic disturbances. The alteration in pacing strategy following the first exercise bout is compatible with a complex intelligent regulatory system.

Human cytochrome c enters murine J774 cells and causes G1 and G2/M cell cycle arrest and induction of apoptosis

International Nuclear Information System (INIS)

Hiraoka, Yoshinori; Granja, Ana Teresa; Fialho, Arsenio M.; Schlarb-Ridley, Beatrix G.; Das Gupta, Tapas K.; Chakrabarty, Ananda M.; Yamada, Tohru

2005-01-01

Cytochrome c is well known as a carrier of electrons during respiration. Current evidence indicates that cytochrome c also functions as a major component of apoptosomes to induce apoptosis in eukaryotic cells as well as an antioxidant. More recently, a prokaryotic cytochrome c, cytochrome c 551 from Pseudomonas aeruginosa, has been shown to enter in mammalian cells such as the murine macrophage-like J774 cells and causes inhibition of cell cycle progression. Much less is known about such functions by mammalian cytochromes c, particularly the human cytochrome c. We now report that similar to P. aeruginosa cytochrome c 551 , the purified human cytochrome c protein can enter J774 cells and induce cell cycle arrest at the G 1 to S phase, as well as at the G 2 /M phase at higher concentrations. Unlike P. aeruginosa cytochrome c 551 which had no effect on the induction of apoptosis, human cytochrome c induces significant apoptosis and cell death in J774 cells, presumably through inhibition of the cell cycle at the G 2 /M phase. When incubated with human breast cancer MCF-7 and normal mammary epithelial cell line MCF-10A1 cells, human cytochrome c entered in both types of cells but induced cell death only in the normal MCF-10A1 cells. The ability of human cytochrome c to enter J774 cells was greatly reduced at 4 deg. C, suggesting energy requirement in the entry process

Integration of indirect CO2 emissions from the full energy chain

International Nuclear Information System (INIS)

Yasukawa, S.; Tadokoro, Y.; Sato, O.; Yamaguchi, M.

1996-01-01

The methodologies of life-cycle analysis are discussed. The system boundaries have to be adequately defined, which is illustrated with the example of coal-fired electricity generation. The input/output method of LCA is discussed, including the incorporation of material recycling in the analysis. Also discussed is the linkage of engineering and economic approaches together with the necessary improvements of MARKAL in order to integrate the indirect processes. Finally examples are given of the analysis of the direct and indirect CO 2 emission from a pressurized-water reactor and its fuel cycle. The analysis shows that the life-cycle CO 2 emission coefficient is 25.7 g CO 2 /kW.h in case of gas-diffusion enrichment, whereas in case of centrifuge enrichment this emission coefficient amounts to 7.9 g CO 2 /kW.h only. (author). 9 refs, 8 figs, 3 tabs

J/psi physics at BEPC

International Nuclear Information System (INIS)

Chanowitz, M.S.

1984-06-01

J/psi physics is discussed which will be of interest at T > 1988, the period of operation of the Beijing Electron Positron Collider. Emphasis is placed on the gluonic states which are best studied in radiative J/psi decay. The difficulties of these studies are discussed and the need for very high statistics is stressed. In particular it is essential to partial-wave-analyze the hadronic final states produced in J/psi → γX. An estimate using fixed target data suggests that 0(10 8 ) J/psi decays are needed to do an unambiguous partial wave analysis for hadron masses up to about 2 GeV. This requirement is an excellent match to the BEPC design parameters, which imply production of 0(10 8 ) J/psi's per year. With a J/psi production rate an order of magnitude greater than other electron-positron storage rings, BEPC will be a unique world facility for these studies. 58 references

Influence of the Southern Hemisphere Circulations on the Active-Break Cycle of the Indian Summer Monsoon

OpenAIRE

Tetsuzo, Yasunari

1981-01-01

During the northerm summer monsoon period, the cloudiness fluctuation over and around India shows a predominant periodicity of 30 to 40 days as a major active-break cycle of monsoon activity, and this fluctuation appears as a northward phase shift of maximum (or minimum) cloudiness from the equatorial Indian Ocean toward the Himalayas (T. YASUNARI : J. Meteorol. Soc. Jpn, 57,227,1979; ibid., 58,225,1980). It has also been revealed that the northward movement of the cloudiness with this period...

Water augmented indirectly-fired gas turbine systems and method

Science.gov (United States)

Bechtel, Thomas F.; Parsons, Jr., Edward J.

1992-01-01

An indirectly-fired gas turbine system utilizing water augmentation for increasing the net efficiency and power output of the system is described. Water injected into the compressor discharge stream evaporatively cools the air to provide a higher driving temperature difference across a high temperature air heater which is used to indirectly heat the water-containing air to a turbine inlet temperature of greater than about 1,000.degree. C. By providing a lower air heater hot side outlet temperature, heat rejection in the air heater is reduced to increase the heat recovery in the air heater and thereby increase the overall cycle efficiency.

A comparison of the impact of direct and indirect benefits of mating decisions in the rose bitterling (Rhodeus ocellatus)

Czech Academy of Sciences Publication Activity Database

Agbali, M.; Spence, R.; Reichard, Martin; Smith, C.

2012-01-01

Roč. 58, č. 4 (2012), s. 279-288 ISSN 1565-9801 R&D Projects: GA ČR GA206/09/1163 Institutional support: RVO:68081766 Keywords : bitterling * direct selection * indirect selection * mate choice * oviposition * Rhodeus ocellatus Subject RIV: EG - Zoology Impact factor: 0.444, year: 2012 http://www.tandfonline.com/doi/abs/10.1560/IJEE.58.4.279

Utility of large spot binocular indirect laser delivery for peripheral photocoagulation therapy in children.

Science.gov (United States)

Balasubramaniam, Saranya C; Mohney, Brian G; Bang, Genie M; Link, Thomas P; Pulido, Jose S

2012-09-01

The purpose of this article is to demonstrate the utility of the large spot size (LSS) setting using a binocular laser indirect delivery system for peripheral ablation in children. One patient with bilateral retinopathy of prematurity received photocoagulation with standard spot size burns placed adjacently to LSS burns. Using a pixel analysis program called Image J on the Retcam picture, the areas of each retinal spot size were determined in units of pixels, giving a standard spot range of 805 to 1294 pixels and LSS range of 1699 to 2311 pixels. Additionally, fluence was calculated using theoretical retinal areas produced by each spot size: the standard spot setting was 462 mJ/mm2 and the LSS setting was 104 mJ/mm2. For eyes with retinopathy of prematurity, our study shows that LSS laser indirect delivery halves the number of spots required for treatment and reduces fluence by almost one-quarter, producing more uniform spots.

Symmetry rules for the indirect nuclear spin-spin coupling tensor revisited

Science.gov (United States)

Buckingham, A. D.; Pyykkö, P.; Robert, J. B.; Wiesenfeld, L.

The symmetry rules of Buckingham and Love (1970), relating the number of independent components of the indirect spin-spin coupling tensor J to the symmetry of the nuclear sites, are shown to require modification if the two nuclei are exchanged by a symmetry operation. In that case, the anti-symmetric part of J does not transform as a second-rank polar tensor under symmetry operations that interchange the coupled nuclei and may be called an anti-tensor. New rules are derived and illustrated by simple molecular models.

VARIATIONS OF ABSORPTION TROUGHS IN THE QUASAR SDSS J125216.58+052737.7

Energy Technology Data Exchange (ETDEWEB)

Chen, Zhi-Fu [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China); Qin, Yi-Ping, E-mail: zhichenfu@126.com [Department of Physics and Telecommunication Engineering, Baise University, Baise 533000 (China)

2015-01-20

In this work, we analyze the spectra of quasar J125216.58+052737.7 (z {sub em} = 1.9035) which was observed by SDSS-I/II on 2003 January 30 and by BOSS on 2011 April 2. Both the continuum and the absorption spectra of this quasar show obvious variations between the two epochs. In the SDSS-I/II spectrum, we detect 8 C IV λλ1548,1551 absorption systems, which are detected at z {sub abs} = 1.9098, 1.8948, 1.8841, 1.8770, 1.8732, 1.8635, 1.8154, and 1.7359, respectively, and one Mg II λλ2796,2803 absorption system at z {sub abs} = 0.9912. Among these absorption systems, two C IV λλ1548,1551 absorption systems at z {sub abs} = 1.9098 and 1.7359 and the Mg II λλ2796,2803 absorption system are imprinted on the BOSS spectrum as well, and have similar absorption strengths when compared to those measured from the SDSS-I/II spectrum. Three C IV λλ1548,1551 absorption systems at z {sub abs} = 1.8948, 1.8841, and 1.8770 are also detected in the BOSS spectrum, while their absorption strengths are much weaker than those measured from the SDSS-I/II spectrum; three systems at z {sub abs} = 1.8732, 1.8635, and 1.8154 disappeared from the BOSS spectrum. Based on the variability analysis, the absorption systems that disappeared and weakened are likely to be intrinsic to the quasar. If these intrinsic absorption gases are blown away from the central region of the quasar, with respect to the quasar system, the absorption systems that disappeared would have separation velocities of 3147 kms{sup –1}, 4161 km s{sup –1}, and 9241 km s{sup –1}, while the absorption systems that weakened would have separation velocities of 900 km s{sup –1}, 2011 km s{sup –1}, and 2751 km s{sup –1}. Well-coordinated variations of the six C IV λλ1548,1551 absorption systems that disappeared and weakened, occurring on a timescale of 1026.7 days at the quasar rest frame, can be interpreted as a result of global changes in the ionization state of the absorbing gas.

58. "Berlinale" lõppmäng / Jaak Lõhmus

Index Scriptorium Estoniae

Lõhmus, Jaak

2008-01-01

Berliini 58. filmifestivali auhinnasaajatest : Kuldkaru võitis Brasiilia produtsendi ja režissööri Jose Padilha mängufilm "Eliitrühm", Hõbekaru USA režissööri Errol Morrise dokfilm "Tavaprotseduur". Parima režissööri Hõbekaru läks Paul Thomas Andersonile mängufilmi "Veri hakkab voolama" eest. Parima näitleja auhinna said Sally Hawkins ja Reza Naji, Alfred Baueri auhinna sai Fernando Eimbcke "Tahoe järv"

Cell cycle phases in the unequal mother/daughter cell cycles of Saccharomyces cerevisiae.

Science.gov (United States)

Brewer, B J; Chlebowicz-Sledziewska, E; Fangman, W L

1984-11-01

During cell division in the yeast Saccharomyces cerevisiae mother cells produce buds (daughter cells) which are smaller and have longer cell cycles. We performed experiments to compare the lengths of cell cycle phases in mothers and daughters. As anticipated from earlier indirect observations, the longer cell cycle time of daughter cells is accounted for by a longer G1 interval. The S-phase and the G2-phase are of the same duration in mother and daughter cells. An analysis of five isogenic strains shows that cell cycle phase lengths are independent of cell ploidy and mating type.

Life cycle assessment in support of sustainable transportation

Science.gov (United States)

Eckelman, Matthew J.

2013-06-01

cycle GHG and air pollutant emissions. A related study in Toronto on life cycle energy use and GHG emissions for high- and low-density development strategies found a ~60% difference in GHG emissions, largely due to transportation (Norman et al 2006). System dynamics and agent-based models may complement LCA in capturing long-term effects of transportation strategies as they are inherently dynamic (Stepp et al 2009), and can internalize spatially resolved decisions about where to settle and work (Waddell 2002). Transportation planning decisions have both direct and indirect, spatially distributed, often long-term effects on our health and our environment. The accompanying work by Chester et al (2013) provides a well-documented case study that highlights the potential of LCA as a rich source of decision support. References Chester M, Pincetl S, Elizabeth Z, Eisenstein W and Matute J 2013 Infrastructure and automobile shifts: positioning transit to reduce life-cycle environmental impacts for urban sustainability goals Environ. Res. Lett. 8 015041 Chester M V and Horvath A 2009 Environmental assessment of passenger transportation should include infrastructure and supply chains Environ. Res. Lett. 4 024008 Fargione J, Hill J, Tilman D, Polasky S and Hawthorne P 2008 Land clearing and the biofuel carbon debt Science 319 1235-8 Kennedy C, Steinberger J, Gasson B, Hansen Y, Hillman T, Havránek M, Pataki D, Phdungsilp A, Ramaswami A and Mendez G V 2009 Greenhouse gas emissions from global cities Environ. Sci. Technol. 43 7297-302 Kunstler J H 1994 Geography of Nowhere: The Rise and Decline of America's Man-Made Landscape (New York: Free Press) Mashayekh Y, Jaramillo P, Samaras C, Hendrickson C T, Blackhurst M, MacLean H L and Matthews H S 2012 Potentials for sustainable transportation in cities to alleviate climate change impacts Environ. Sci. Technol. 46 2529-37 Mutel C L and Hellweg S 2009 Regionalized life cycle assessment: computational methodology and application to

Evaluation of Indirect Combined Cycle in Very High Temperature Gas--Cooled Reactor

International Nuclear Information System (INIS)

Chang Oh; Robert Barner; Cliff Davis; Steven Sherman; Paul Pickard

2006-01-01

The U.S. Department of Energy and Idaho National Laboratory are developing a very high temperature reactor to serve as a demonstration of state-of-the-art nuclear technology. The purpose of the demonstration is twofold: (a) efficient, low-cost energy generation and (b) hydrogen production. Although a next-generation plant could be developed as a single-purpose facility, early designs are expected to be dual purpose, as assumed here. A dual-purpose design with a combined cycle of a Brayton top cycle and a bottom Rankine cycle was investigated. An intermediate heat transport loop for transporting heat to a hydrogen production plant was used. Helium, CO2, and a helium-nitrogen mixture were studied to determine the best working fluid in terms of the cycle efficiency. The relative component sizes were estimated for the different working fluids to provide an indication of the relative capital costs. The relative size of the turbomachinery was measured by comparing the power input/output of the component. For heat exchangers the volume was computed and compared. Parametric studies away from the baseline values of the cycle were performed to determine the effects of varying conditions in the cycle. This gives some insight into the sensitivity of the cycle to various operating conditions as well as trade-offs between efficiency and component size. Parametric studies were carried out on reactor outlet temperature, mass flow, pressure, and turbine cooling

The Role of Mediators in the Indirect Effects of Religiosity on Therapeutic Compliance in African Migrant HIV-Positive Patients.

Science.gov (United States)

Mambet Doue, Constance; Roussiau, Nicolas

2016-12-01

This research investigates the indirect effects of religiosity (practice and belief) on therapeutic compliance in 81 HIV-positive patients who are migrants from sub-Saharan Africa (23 men and 58 women). Using analyses of mediation and standard multiple regression, including a resampling procedure by bootstrapping, the role of these mediators (magical-religious beliefs and nonuse of toxic substances) was tested. The results show that, through magical-religious beliefs, religiosity has a negative indirect effect, while with the nonuse of toxic substances, religious practice has a positive indirect effect. Beyond religiosity, the role of mediators is highlighted in the interaction with therapeutic compliance.

Thermo-economic analysis of recuperated Maisotsenko bottoming cycle using triplex air saturator: Comparative analyses

International Nuclear Information System (INIS)

Saghafifar, Mohammad; Omar, Amr; Erfanmoghaddam, Sepehr; Gadalla, Mohamed

2017-01-01

Highlights: • Proposing recuperated Maisotsenko bottoming cycle (RMBC) as a new combined cycle. • Introducing triplex air saturator for waste heat recovery application. • Conducting thermodynamic optimization to maximize RMBC thermal efficiency. • Conducting thermo-economic optimization to minimize RMBC cost of electricity. - Abstract: A recently recommended combined cycle power plant is to employ another gas turbine cycle for waste heat recovery as an air bottoming cycle (ABC). There are some studies conducted to improve ABC’s thermodynamic performance utilizing commonly power augmentation methods such as steam/water injection. In particular, it is proposed to employ Maisotsenko gas turbine cycle as a bottoming cycle, i.e. Maisotsenko bottoming cycle (MBC). Due to the promising performance of the MBC configuration, it is decided to investigate a recuperated MBC (RMBC) configuration by recommending the triplex air saturator. In this way, the air saturator consists of three sections. The first section is an indirect evaporative cooler while the other two sections are responsible for heat recovery from the topping and bottoming cycle turbines exhaust. In this paper, thermodynamic and thermo-economic analyses are carried out to study the main merits and demerits of RMBC against MBC configuration. Thermodynamic optimization results indicate that the maximum achievable efficiency for MBC and RMBC incorporation in a simple gas turbine power plant are 39.40% and 44.73%, respectively. Finally, thermo-economic optimization shows that the optimum levelized cost of electricity for MBC and RMBC power plants are 62.922 US$/MWh and 58.154 US$/MWh, respectively.

Calculation of the emergency condenser of the indirect cycle reactor CAREM

International Nuclear Information System (INIS)

Walter, D.; Schaffrath, A.

2002-08-01

CAREM is an Argentine project to achieve the development, design and construction of an innovative, simple and small Nuclear Power Plant (NPP). This NPP has an indirect cycle reactor with some distinctive and characteristic features (e.g. integrated primary cooling system by natural circulation, self-pressurized primary system and passive safety systems, etc.). In the frame of an IAEA forwarded HUMAN RESOURCES DEVELOPMENT - 'Advice on CAREM passive emergency condenser' at the Centro Atomico in San Carlos de Bariloche (Argentina) German experimental as well as analytical investigations of passive safety systems - mainly performed at the research centers Juelich and Rossendorf - were presented. During this visit it was decided that FZR should determine the emergency condenser capacity by using the ATHLET code with and without the condensation module extension KONWAR (condensation inside horizontal tube). These results should be compared and assessed with existing RELAP calculations. The ATHLET and ATHLET/KONWAR calculations of the emergency condenser were used for minimizing the user influence performed with exactly the same nodalization scheme and the same initial and boundary conditions than the RELAP calculations. The comparison of all three computational results shows that the required condenser capacities were achieved. The magnitudes were in order of up to 12%. An additionally performed evaluation of local flow parameters show large deviations especially for the heat transfer coefficients at the inner and outer tube wall. Due to the good validation progress of KONWAR by an extensive module validation against NOKO and HORUS experiments, the focus of the further investigation were concentrated on the boiling heat transfer. A comparison of the ATHLET boiling model (according to Forster and Zuber in combination with the equation of Thom for the determination of temperature difference between wall and saturated fluid) with other models from literature (Borishansky

Melatonin, Light and Circadian Cycles

Science.gov (United States)

1989-12-25

Neurosci Abstr 14:848. Fanget, F., Claustrat, B., Dalery, J., Brun, J., Terra , J-L, Marie-Cardine, M., and Guyotot, J. (1989) Nocturnal plasma melatonin...5- methoxytryptamine, a novel melatonin antagonist: effects on sexual matura - tion of the male and female rat and on uestrous cycles of the female rat

Recent results for /sup 58/Ni and /sup 56/Fe at ORELA. [Widths, J,. pi. ]. EVEL WIDTHS; LEVEL WIDTHS; PARITY; SPIN; ANGULAR DISTRIBUTION; FAST NEUTRONS; KEV RANGE 100-1000; MEV RANGE 01-10

Energy Technology Data Exchange (ETDEWEB)

Perey, F.G.; Chapman, G.T.; Kinney, W.E.; Perey, C.M.

1977-12-01

Transmission and capture data from /sup 58/Ni were analyzed up to 120 keV and are reported. High-resolution scattering measurements for Fe are discussed, and the determination of the J/sup ..pi../ value for most resonances seen in transmission data up to 400 keV is given, including an attempt at evaluation of the resonances of /sup 56/Fe on the basis of recently published data. 4 figures, 3 tables.

ENERGY EFFICIENCY LIMITS FOR A RECUPERATIVE BAYONET SULFURIC ACID DECOMPOSITION REACTOR FOR SULFUR CYCLE THERMOCHEMICAL HYDROGEN PRODUCTION

Energy Technology Data Exchange (ETDEWEB)

Gorensek, M.; Edwards, T.

2009-06-11

A recuperative bayonet reactor design for the high-temperature sulfuric acid decomposition step in sulfur-based thermochemical hydrogen cycles was evaluated using pinch analysis in conjunction with statistical methods. The objective was to establish the minimum energy requirement. Taking hydrogen production via alkaline electrolysis with nuclear power as the benchmark, the acid decomposition step can consume no more than 450 kJ/mol SO{sub 2} for sulfur cycles to be competitive. The lowest value of the minimum heating target, 320.9 kJ/mol SO{sub 2}, was found at the highest pressure (90 bar) and peak process temperature (900 C) considered, and at a feed concentration of 42.5 mol% H{sub 2}SO{sub 4}. This should be low enough for a practical water-splitting process, even including the additional energy required to concentrate the acid feed. Lower temperatures consistently gave higher minimum heating targets. The lowest peak process temperature that could meet the 450-kJ/mol SO{sub 2} benchmark was 750 C. If the decomposition reactor were to be heated indirectly by an advanced gas-cooled reactor heat source (50 C temperature difference between primary and secondary coolants, 25 C minimum temperature difference between the secondary coolant and the process), then sulfur cycles using this concept could be competitive with alkaline electrolysis provided the primary heat source temperature is at least 825 C. The bayonet design will not be practical if the (primary heat source) reactor outlet temperature is below 825 C.

Dark matter in dwarf spheroidal galaxies and indirect detection: a review.

Science.gov (United States)

Strigari, Louis E

2018-05-01

Indirect dark matter searches targeting dwarf spheroidal galaxies (dSphs) have matured rapidly during the past decade. This has been because of the substantial increase in kinematic data sets from the dSphs, the new dSphs that have been discovered, and the operation of the Fermi-LAT and many ground-based gamma-ray experiments. Here we review the analysis methods that have been used to determine the dSph dark matter distributions, in particular the 'J-factors', comparing and contrasting them, and detailing the underlying systematics that still affect the analysis. We discuss prospects for improving measurements of dark matter distributions, and how these interplay with future indirect dark matter searches.

Dark matter in dwarf spheroidal galaxies and indirect detection: a review

Science.gov (United States)

Strigari, Louis E.

2018-05-01

Indirect dark matter searches targeting dwarf spheroidal galaxies (dSphs) have matured rapidly during the past decade. This has been because of the substantial increase in kinematic data sets from the dSphs, the new dSphs that have been discovered, and the operation of the Fermi-LAT and many ground-based gamma-ray experiments. Here we review the analysis methods that have been used to determine the dSph dark matter distributions, in particular the ‘J-factors’, comparing and contrasting them, and detailing the underlying systematics that still affect the analysis. We discuss prospects for improving measurements of dark matter distributions, and how these interplay with future indirect dark matter searches.

Endometrioid endometrial carcinoma indirectly caused by pituitary prolactinoma: a case report.

Science.gov (United States)

Nishino, Kimihiro; Niwa, Yuri; Mizutani, Teruyuki; Shimizu, Ken; Hayashi, Kazumasa; Chaya, Jyunya; Kato, Noriko; Yamamuro, Osamu

2013-01-01

We present the case of a 44-year-old nulliparous woman who experienced irregular menstrual cycles for about 10 years and developed both pituitary prolactinoma and endometrioid endometrial carcinoma. In premenopausal women, hyperprolactinemia causes hypogonadism by inhibiting secretion of gonadotropin-releasing hormone and thus suppressing luteinizing hormone levels, which can cause menstrual disorders ranging from amenorrhea, oligomenorrhea and chronic anovulatory cycle to short luteal phase of the menstrual cycle. A chronic anovulatory menstrual cycle is the most common cause of long-term exposure of the endometrium to endogenous estrogen without adequate opposition from progestins, which can lead to endometrioid endometrial carcinoma. In this case, pituitary prolactinoma may have caused the chronic anovulatory cycle and indirectly led to the endometrioid endometrial carcinoma. In patients for whom the cause of irregular menstruation and chronic anovulatory cycle is suspected to be hyperprolactinemia, explorations of both the hypophysis and endometrium are essential.

Endometrioid Endometrial Carcinoma Indirectly Caused by Pituitary Prolactinoma:A Case Report

Directory of Open Access Journals (Sweden)

Kimihiro Nishino

2013-01-01

Full Text Available We present the case of a 44-year-old nulliparous woman who experienced irregular menstrual cycles for about 10 years and developed both pituitary prolactinoma and endometrioid endometrial carcinoma. In premenopausal women, hyperprolactinemia causes hypogonadism by inhibiting secretion of gonadotropin-releasing hormone and thus suppressing luteinizing hormone levels, which can cause menstrual disorders ranging from amenorrhea, oligomenorrhea and chronic anovulatory cycle to short luteal phase of the menstrual cycle. A chronic anovulatory menstrual cycle is the most common cause of long-term exposure of the endometrium to endogenous estrogen without adequate opposition from progestins, which can lead to endometrioid endometrial carcinoma. In this case, pituitary prolactinoma may have caused the chronic anovulatory cycle and indirectly led to the endometrioid endometrial carcinoma. In patients for whom the cause of irregular menstruation and chronic anovulatory cycle is suspected to be hyperprolactinemia, explorations of both the hypophysis and endometrium are essential.

The physical and functional interaction of NDRG2 with MSP58 in cells

International Nuclear Information System (INIS)

Zhang Jing; Liu Junye; Li Xia; Li Fuyang; Wang Lifeng; Zhang Jian; Liu Xinping; Shen Lan; Liu Na; Deng Yanchun; Yang Angang; Han Hua; Zhao Mujun; Yao Libo

2007-01-01

NDRG2, a member of N-Myc downstream regulated gene family, exerts the important functions in cell differentiation and tumor suppression. Although the ectopic expressed Ndrg2 inhibits the proliferation of tumor cells, its intracellular signal transduction pathway is hardly known. Here, we identified MSP58, a 58-kDa microspherule protein, as an interacting partner of human Ndrg2 by using yeast two-hybrid screening. The interaction was confirmed by glutathione S-transferase pull-down assay in vitro and by co-immune-precipitation assay in vivo. The forkhead associated domain of MSP58 is essential for its interaction with Ndrg2. Ndrg2 could co-localize with MSP58 in nuclear of HeLa cell during cell stress. Furthermore, the modulation of Ndrg2 level influences the cell cycle process together with MSP58. In conclusion, the findings offered a novel insight into the physiological roles of Ndrg2

Critical role of CDK11p58 in human breast cancer growth and angiogenesis

International Nuclear Information System (INIS)

Chi, Yayun; Huang, Sheng; Peng, Haojie; Liu, Mengying; Zhao, Jun; Shao, Zhiming; Wu, Jiong

2015-01-01

A capillary network is needed in cancer growth and metastasis. Induction of angiogenesis represents one of the major hallmarks of cancer. CDK11 p58 , a Ser/Thr kinase that belongs to the Cell Division Cycle 2-like 1 (CDC2L1) subfamily is associated with cell cycle progression, tumorigenesis, sister chromatid cohesion and apoptotic signaling. However, its role in breast cancer proliferation and angiogenesis remains unclear. Tumorigenicity assays and blood vessel assessment in athymic mice were used to assess the function of CDK11 p58 in tumor proliferation and angiogenesis. CCK-8 assay was used to detect breast cancer cell growth. Immunohistochemistry was used to detect the expression of vascular endothelial growth factor (VEGF), CD31 and CD34 in CDK11 positive patient breast cancer tissues. Dual-Luciferase array was used to analyze the function of CDK11 p58 in the regulation of VEGF promoter activity. Western blot was used to detect related protein expression levels. CDK11 p58 inhibited breast cancer growth and angiogenesis in breast cancer cells and in nude mice transplanted with tumors. Immunohistochemistry confirmed that CDK11 p58 was negatively associated with angiogenesis-related proteins such as VEGF, CD31 and CD34 in breast cancer patients. Real-time PCR and dual-luciferase assay showed CDK11 p58 inhibited the mRNA levels of VEGF and the promoter activity of VEGF. As CDK11 p58 is a Ser/Thr kinase, the kinase-dead mutant failed to inhibit VEGF mRNA and promoter activity. Western blot analysis showed the same pattern of related protein expression. The data suggested angiogenesis inhibition was dependent on CDK11 p58 kinase activity. This study indicates that CDK11 p58 inhibits the growth and angiogenesis of breast cancer dependent on its kinase activity. The online version of this article (doi:10.1186/s12885-015-1698-7) contains supplementary material, which is available to authorized users

Sensitivity of aerosol indirect forcing and autoconversion to cloud droplet parameterization: an assessment with the NASA Global Modeling Initiative.

Science.gov (United States)

Sotiropoulou, R. P.; Meshkhidze, N.; Nenes, A.

2006-12-01

The aerosol indirect forcing is one of the largest sources of uncertainty in assessments of anthropogenic climate change [IPCC, 2001]. Much of this uncertainty arises from the approach used for linking cloud droplet number concentration (CDNC) to precursor aerosol. Global Climate Models (GCM) use a wide range of cloud droplet activation mechanisms ranging from empirical [Boucher and Lohmann, 1995] to detailed physically- based formulations [e.g., Abdul-Razzak and Ghan, 2000; Fountoukis and Nenes, 2005]. The objective of this study is to assess the uncertainties in indirect forcing and autoconversion of cloud water to rain caused by the application of different cloud droplet parameterization mechanisms; this is an important step towards constraining the aerosol indirect effects (AIE). Here we estimate the uncertainty in indirect forcing and autoconversion rate using the NASA Global Model Initiative (GMI). The GMI allows easy interchange of meteorological fields, chemical mechanisms and the aerosol microphysical packages. Therefore, it is an ideal tool for assessing the effect of different parameters on aerosol indirect forcing. The aerosol module includes primary emissions, chemical production of sulfate in clear air and in-cloud aqueous phase, gravitational sedimentation, dry deposition, wet scavenging in and below clouds, and hygroscopic growth. Model inputs include SO2 (fossil fuel and natural), black carbon (BC), organic carbon (OC), mineral dust and sea salt. The meteorological data used in this work were taken from the NASA Data Assimilation Office (DAO) and two different GCMs: the NASA GEOS4 finite volume GCM (FVGCM) and the Goddard Institute for Space Studies version II' (GISS II') GCM. Simulations were carried out for "present day" and "preindustrial" emissions using different meteorological fields (i.e. DAO, FVGCM, GISS II'); cloud droplet number concentration is computed from the correlations of Boucher and Lohmann [1995], Abdul-Razzak and Ghan [2000

Integrating Life-cycle Assessment into Transport Cost-benefit Analysis

DEFF Research Database (Denmark)

Manzo, Stefano; Salling, Kim Bang

2016-01-01

Traditional transport Cost-Benefit Analysis (CBA) commonly ignores the indirect environmental impacts of an infrastructure project deriving from the overall life-cycle of the different project components. Such indirect impacts are instead of key importance in order to assess the long......-term sustainability of a transport infrastructure project. In the present study we suggest to overcome this limit by combining a conventional life-cycle assessment approach with standard transport cost-benefit analysis. The suggested methodology is tested upon a case study project related to the construction of a new...... fixed link across the Roskilde fjord in Frederikssund (Denmark). The results are then compared with those from a standard CBA framework. The analysis shows that indirect environmental impacts represent a relevant share of the estimated costs of the project, clearly affecting the final project evaluation...

Covariance J-resolved spectroscopy: Theory and application in vivo.

Science.gov (United States)

Iqbal, Zohaib; Verma, Gaurav; Kumar, Anand; Thomas, M Albert

2017-08-01

Magnetic resonance spectroscopy (MRS) is a powerful tool capable of investigating the metabolic status of several tissues in vivo. In particular, single-voxel-based 1 H spectroscopy provides invaluable biochemical information from a volume of interest (VOI) and has therefore been used in a variety of studies. Unfortunately, typical one-dimensional MRS data suffer from severe signal overlap and thus important metabolites are difficult to distinguish. One method that is used to disentangle overlapping resonances is the two-dimensional J-resolved spectroscopy (JPRESS) experiment. Due to the long acquisition duration of the JPRESS experiment, a limited number of points are acquired in the indirect dimension, leading to poor spectral resolution along this dimension. Poor spectral resolution is problematic because proper peak assignment may be hindered, which is why the zero-filling method is often used to improve resolution as a post-processing step. However, zero-filling leads to spectral artifacts, which may affect visualization and quantitation of spectra. A novel method utilizing a covariance transformation, called covariance J-resolved spectroscopy (CovJ), was developed in order to improve spectral resolution along the indirect dimension (F 1 ). Comparison of simulated data demonstrates that peak structures remain qualitatively similar between JPRESS and the novel method along the diagonal region (F 1 = 0 Hz), whereas differences arise in the cross-peak (F 1 ≠0 Hz) regions. In addition, quantitative results of in vivo JPRESS data acquired on a 3T scanner show significant correlations (r 2 >0.86, pCOVariance Spectral Evaluation of 1 H Acquisitions using Representative prior knowledge' (Cov-SEHAR), was developed in order to quantify γ-aminobutyric acid and glutamate from the CovJ spectra. These preliminary findings indicate that the CovJ method may be used to improve spectral resolution without hindering metabolite quantitation for J-resolved spectra

Energy metabolism in BPH/2J genetically hypertensive mice.

Science.gov (United States)

Jackson, Kristy L; Nguyen-Huu, Thu-Phuc; Davern, Pamela J; Head, Geoffrey A

2014-05-01

Recent evidence indicates that genetic hypertension in BPH/2J mice is sympathetically mediated, but these mice also have lower body weight (BW) and elevated locomotor activity compared with BPN/3J normotensive mice, suggestive of metabolic abnormalities. The aim of the present study was to determine whether hypertension in BPH/2J mice is associated with metabolic differences. Whole-body metabolic and cardiovascular parameters were measured over 24 h by indirect calorimetry and radiotelemetry respectively, in conscious young (10-13 weeks) and older (22-23 weeks) BPH/2J, normotensive BPN/3J and C57Bl6 mice. Blood pressure (BP) was greater in BPH/2J compared with both normotensive strains at both ages (PBPH/2J compared with BPN/3J mice (PBPH/2J and normotensive mice when adjusted for activity (P>0.1) suggesting differences in this relationship are not responsible for hypertension. EchoMRI revealed that percentage body composition was comparable in BPN/3J and BPH/2J mice (P>0.1) and both strains gained weight similarly with age (P=0.3). Taken together, the present findings indicate that hypertension in BPH/2J mice does not appear to be related to altered energy metabolism.

Parametric studies on different gas turbine cycles for a high temperature gas-cooled reactor

International Nuclear Information System (INIS)

Wang Jie; Gu Yihua

2005-01-01

The high temperature gas-cooled reactor (HTGR) coupled with turbine cycle is considered as one of the leading candidates for future nuclear power plants. In this paper, the various types of HTGR gas turbine cycles are concluded as three typical cycles of direct cycle, closed indirect cycle and open indirect cycle. Furthermore they are theoretically converted to three Brayton cycles of helium, nitrogen and air. Those three types of Brayton cycles are thermodynamically analyzed and optimized. The results show that the variety of gas affects the cycle pressure ratio more significantly than other cycle parameters, however, the optimized cycle efficiencies of the three Brayton cycles are almost the same. In addition, the turbomachines which are required for the three optimized Brayton cycles are aerodynamically analyzed and compared and their fundamental characteristics are obtained. Helium turbocompressor has lower stage pressure ratio and more stage number than those for nitrogen and air machines, while helium and nitrogen turbocompressors have shorter blade length than that for air machine

RP58 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Cerebral Cortex

Directory of Open Access Journals (Sweden)

Chiaki Ohtaka-Maruyama

2013-02-01

Full Text Available Accumulating evidence suggests that many brain diseases are associated with defects in neuronal migration, suggesting that this step of neurogenesis is critical for brain organization. However, the molecular mechanisms underlying neuronal migration remain largely unknown. Here, we identified the zinc-finger transcriptional repressor RP58 as a key regulator of neuronal migration via multipolar-to-bipolar transition. RP58−/− neurons exhibited severe defects in the formation of leading processes and never shifted to the locomotion mode. Cre-mediated deletion of RP58 using in utero electroporation in RP58flox/flox mice revealed that RP58 functions in cell-autonomous multipolar-to-bipolar transition, independent of cell-cycle exit. Finally, we found that RP58 represses Ngn2 transcription to regulate the Ngn2-Rnd2 pathway; Ngn2 knockdown rescued migration defects of the RP58−/− neurons. Our findings highlight the critical role of RP58 in multipolar-to-bipolar transition via suppression of the Ngn2-Rnd2 pathway in the developing cerebral cortex.

Indirect water management through Life Cycle Assessment: Fostering sustainable production in developing countries

Science.gov (United States)

Pfister, S.; Bayer, P.; Koehler, A.; Hellweg, S.

2009-04-01

Life Cycle Assessment (LCA) represents a methodological framework for analyzing the total environmental impact of any product or service of our daily life. After tracking all associated emissions and the consumption of resources, this impact is expressed with respect to a few common impact categories. These are supposed to reflect major societal and environmental priorities. However, despite their central role in environmental processes, to date hydrological as well as hydrogeological aspects are only rarely considered in LCA. Compared with standard impact categories within LCA, water is special. In contrast to other abiotic resources such as crude oil, it can be replenished. Total freshwater resources are immense, but not evenly distributed and often scarce in regions of high demand. Consequently, threads to natural water bodies have immense spatial dependency. Setting up functional relationships in order to derive a generally valid and practicable evaluation is tedious due to the complex, insufficiently understood, and uncertain natural processes involved. LCA that includes the environmental effects of water consumption means global indirect water resource management. It supports goal-directed consumer behaviour that aims to reduce pressure on natural water systems. By developing a hydrologically-based assessment of potential impacts from human interaction with natural water bodies, "greener" products can be prioritised. More sustainable and environmentally friendly water management is the result. The proposed contribution presents an operational assessment method of global surface water consumption for impacts on human health and ecosystem quality within a LCA framework. A major focus is the issue of how such global assessment helps to quantify potential impacts from water-intensive production in developing countries, where the means for proper water management are often limited. We depict a compensation scheme for impacts related to water consumption that

CDK11p58 represses vitamin D receptor-mediated transcriptional activation through promoting its ubiquitin-proteasome degradation

International Nuclear Information System (INIS)

Chi, Yayun; Hong, Yi; Zong, Hongliang; Wang, Yanlin; Zou, Weiying; Yang, Junwu; Kong, Xiangfei; Yun, Xiaojing; Gu, Jianxin

2009-01-01

Vitamin D receptor (VDR) is a member of the nuclear receptor superfamily and regulates transcription of target genes. In this study, we identified CDK11 p58 as a novel protein involved in the regulation of VDR. CDK11 p58 , a member of the large family of p34cdc2-related kinases, is associated with cell cycle progression, tumorigenesis, and apoptotic signaling. Our study demonstrated that CDK11 p58 interacted with VDR and repressed VDR-dependent transcriptional activation. Furthermore, overexpression of CDK11 p58 decreased the stability of VDR through promoting its ubiquitin-proteasome-mediated degradation. Taken together, these results suggest that CDK11 p58 is involved in the negative regulation of VDR.

Study of J/ψ decaying into ωp anti p

International Nuclear Information System (INIS)

Ablikim, M.; Bai, J.Z.; Cai, X.; Chen, H.S.; Chen, H.X.; Chen, J.C.; Chen, Jin; Chen, Y.B.; Chu, Y.P.; Deng, Z.Y.; Du, S.X.; Fang, J.; Fang, S.S.; Gao, C.S.; Gu, S.D.; Guo, Y.N.; He, K.L.; Heng, Y.K.; Hu, H.M.; Hu, T.; Huang, G.S.; Ji, X.B.; Jiang, X.S.; Jin, D.P.; Jin, S.; Lai, Y.F.; Li, G.; Li, H.B.; Li, J.; Li, R.Y.; Li, S.M.; Li, W.D.; Li, W.G.; Li, X.L.; Li, X.N.; Liao, H.B.; Liu, B.J.; Liu, C.X.; Liu, Fang; Liu, H.H.; Liu, H.M.; Liu, J.B.; Liu, Jian; Liu, R.G.; Liu, Z.A.; Lu, F.; Lu, J.G.; Ma, L.L.; Ma, Q.M.; Mao, Z.P.; Mo, X.H.; Nie, J.; Ping, R.G.; Qi, N.D.; Qin, H.; Qiu, J.F.; Ren, Z.Y.; Rong, G.; Shan, L.Y.; Shang, L.; Shen, D.L.; Shen, X.Y.; Sheng, H.Y.; Sun, H.S.; Sun, S.S.; Sun, Y.Z.; Sun, Z.J.; Tang, X.; Tong, G.L.; Wang, D.Y.; Wang, L.; Wang, L.L.; Wang, L.S.; Wang, M.; Wang, P.; Wang, P.L.; Wang, W.F.; Wang, Y.F.; Wang, Z.; Wang, Z.Y.; Wang, Zheng; Wei, C.L.; Wei, D.H.; Weng, Y.; Wu, N.; Xia, X.M.; Xie, X.X.; Xu, G.F.; Yang, H.X.; Yu, G.W.; Yuan, C.Z.; Yuan, Y.; Zang, S.L.; Zhang, B.X.; Zhang, B.Y.; Zhang, C.C.; Zhang, D.H.; Zhang, H.Q.; Zhang, H.Y.; Zhang, J.W.; Zhang, J.Y.; Zhang, S.H.; Zhao, D.X.; Zhao, J.W.; Zhao, M.G.; Zhao, P.P.; Zhao, W.R.; Zhao, Z.G.; Zheng, J.P.; Zheng, Z.P.; Zhou, L.; Zhu, K.J.; Zhu, Q.M.; Zhu, Y.C.; Zhu, Y.S.; Zhu, Z.A.; Zhuang, B.A.; Zhuang, X.A.; Zou, B.S.; Ban, Y.; Liu, J.; Zhang, Z.X.; Zheng, H.Q.; Chen, H.F.; Yan, M.L.; Ye, Y.X.; Zhang, Z.P.; Dai, Y.S.; Diao, L.Y.; Ma, F.C.; Dong, Q.F.; Fu, C.D.; Gao, Y.N.; Gu, Y.T.; Ruan, X.D.; Guo, Z.J.; Harris, F.A.; Liu, Q.; Olsen, S.L.; Shen, C.P.; Varner, G.S.; He, M.; Huang, X.T.; Jiao, J.B.; Zhang, X.Y.; Hou, J.; Li, X.Q.; Xu, Y.; Hu, J.H.; Yang, Y.X.; Jiang, X.Y.; Lou, Y.C.; Lu, G.R.; Liang, Y.F.; Zhang, Yiyun; Liu, F.; Xu, X.P.; Liu, J.P.; Luo, C.L.; Ma, H.L.; Ye, M.H.; Zeng, Y.

2008-01-01

The decay J/ψ→ωp anti p is studied using a 5.8 x 10 7 J/ψ event sample accumulated with the BES II detector at the Beijing Electron-Positron Collider. The decay branching fraction is measured to be B(J/ψ→ωp anti p)=(9.8±0.3±1.4) x 10 -4 . No significant enhancement near the pp mass threshold is observed, and an upper limit of B(J/ψ→ωX(1860))B(X(1860)→pp) -5 is determined at the 95% confidence level, where X(1860) designates the near-threshold enhancement seen in the p anti p mass spectrum in J/ψ→γp anti p decays. (orig.)

Different sets of ER-resident J-proteins regulate distinct polar nuclear-membrane fusion events in Arabidopsis thaliana.

Science.gov (United States)

Maruyama, Daisuke; Yamamoto, Masaya; Endo, Toshiya; Nishikawa, Shuh-ichi

2014-11-01

Angiosperm female gametophytes contain a central cell with two polar nuclei. In many species, including Arabidopsis thaliana, the polar nuclei fuse during female gametogenesis. We previously showed that BiP, an Hsp70 in the endoplasmic reticulum (ER), was essential for membrane fusion during female gametogenesis. Hsp70 function requires partner proteins for full activity. J-domain containing proteins (J-proteins) are the major Hsp70 functional partners. A. thaliana ER contains three soluble J-proteins, AtERdj3A, AtERdj3B, and AtP58(IPK). Here, we analyzed mutants of these proteins and determined that double-mutant ovules lacking AtP58(IPK) and AtERdj3A or AtERdj3B were defective in polar nuclear fusion. Electron microscopy analysis identified that polar nuclei were in close contact, but no membrane fusion occurred in mutant ovules lacking AtP58(IPK) and AtERdj3A. The polar nuclear outer membrane appeared to be connected via the ER remaining at the inner unfused membrane in mutant ovules lacking AtP58(IPK) and AtERdj3B. These results indicate that ER-resident J-proteins, AtP58(IPK)/AtERdj3A and AtP58(IPK)/AtERdj3B, function at distinct steps of polar nuclear-membrane fusion. Similar to the bip1 bip2 double mutant female gametophytes, the aterdj3a atp58(ipk) double mutant female gametophytes defective in fusion of the outer polar nuclear membrane displayed aberrant endosperm proliferation after fertilization with wild-type pollen. However, endosperm proliferated normally after fertilization of the aterdj3b atp58(ipk) double mutant female gametophytes defective in fusion of the inner membrane. Our results indicate that the polar nuclear fusion defect itself does not cause an endosperm proliferation defect. © The Author 2014. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Part-Load Performance of aWet Indirectly Fired Gas Turbine Integrated with an Organic Rankine Cycle Turbogenerator

Directory of Open Access Journals (Sweden)

Leonardo Pierobon

2014-12-01

Full Text Available Over the last years, much attention has been paid to the development of efficient and low-cost power systems for biomass-to-electricity conversion. This paper aims at investigating the design- and part-load performance of an innovative plant based on a wet indirectly fired gas turbine (WIFGT fueled by woodchips and an organic Rankine cycle (ORC turbogenerator. An exergy analysis is performed to identify the sources of inefficiencies, the optimal design variables, and the most suitable working fluid for the organic Rankine process. This step enables to parametrize the part-load model of the plant and to estimate its performance at different power outputs. The novel plant has a nominal power of 250 kW and a thermal efficiency of 43%. The major irreversibilities take place in the burner, recuperator, compressor and in the condenser. Toluene is the optimal working fluid for the organic Rankine engine. The part-load investigation indicates that the plant can operate at high efficiencies over a wide range of power outputs (50%–100%, with a peak thermal efficiency of 45% at around 80% load. While the ORC turbogenerator is responsible for the efficiency drop at low capacities, the off-design performance is governed by the efficiency characteristics of the compressor and turbine serving the gas turbine unit.

Indirection and computer security.

Energy Technology Data Exchange (ETDEWEB)

Berg, Michael J.

2011-09-01

The discipline of computer science is built on indirection. David Wheeler famously said, 'All problems in computer science can be solved by another layer of indirection. But that usually will create another problem'. We propose that every computer security vulnerability is yet another problem created by the indirections in system designs and that focusing on the indirections involved is a better way to design, evaluate, and compare security solutions. We are not proposing that indirection be avoided when solving problems, but that understanding the relationships between indirections and vulnerabilities is key to securing computer systems. Using this perspective, we analyze common vulnerabilities that plague our computer systems, consider the effectiveness of currently available security solutions, and propose several new security solutions.

The use of gas based energy conversion cycles for sodium fast reactors

International Nuclear Information System (INIS)

Saez, M.; Haubensack, D.; Alpy, N.; Gerber, A.; Daid, F.

2008-01-01

In the frame of Sodium Fast Reactors, CEA, AREVA and EDF are involved in a substantial effort providing both significant expertise and original work in order to investigate the interest to use a gas based energy conversion cycle as an alternative to the classical steam cycle. These gas cycles consist in different versions of the Brayton cycle, various types of gas being considered (helium, nitrogen, argon, separately or mixed, sub or supercritical carbon dioxide) as well as various cycle arrangements (indirect, indirect / combined cycles). The interest of such cycles is analysed in details by thermodynamic calculations and cycle optimisations. The objective of this paper is to provide a comparison between gas based energy conversion cycles from the viewpoint of the overall plant efficiency. Key factors affecting the Brayton cycle efficiency include the turbine inlet temperature, compressors and turbine efficiencies, recuperator effectiveness and cycle pressure losses. A nitrogen Brayton cycle at high pressure (between 100 and 180 bar) could appear as a potential near-term solution of classical gas power conversion system for maximizing the plant efficiency. At long-term, supercritical carbon dioxide Brayton cycle appears very promising for Sodium Fast Reactors, with a potential of high efficiency using even at a core outlet temperature of 545 deg. C. (authors)

Nondegenerate parametric generation of 2.2-mJ, few-cycle 2.05-μm pulses using a mixed phase matching scheme

International Nuclear Information System (INIS)

Xu, Guibao; Wandel, Scott F.; Jovanovic, Igor

2014-01-01

We describe the production of 2.2-mJ, ∼6 optical-cycle-long mid-infrared laser pulses with a carrier wavelength of 2.05 μm in a two-stage β-BaB 2 O 4 nondegenerate optical parametric amplifier design with a mixed phase matching scheme, which is pumped by a standard Ti:sapphire chirped-pulse amplification system. It is demonstrated that relatively high pulse energies, short pulse durations, high stability, and excellent beam profiles can be obtained using this simple approach, even without the use of optical parametric chirped-pulse amplification

Total environmental impacts of biofuels from corn stover using a hybrid life cycle assessment model combining process life cycle assessment and economic input-output life cycle assessment.

Science.gov (United States)

Liu, Changqi; Huang, Yaji; Wang, Xinye; Tai, Yang; Liu, Lingqin; Liu, Hao

2018-01-01

Studies on the environmental analysis of biofuels by fast pyrolysis and hydroprocessing (BFPH) have so far focused only on the environmental impacts from direct emissions and have included few indirect emissions. The influence of ignoring some indirect emissions on the environmental performance of BFPH has not been well investigated and hence is not really understood. In addition, in order to avoid shifting environmental problems from one medium to another, a comprehensive assessment of environmental impacts caused by the processes must quantify the environmental emissions to all media (air, water, and land) in relation to each life cycle stage. A well-to-wheels assessment of the total environmental impacts resulting from direct emissions and indirect emissions of a BFPH system with corn stover is conducted using a hybrid life cycle assessment (LCA) model combining the economic input-output LCA and the process LCA. The Tool for the Reduction and Assessment of Chemical and other environmental Impacts (TRACI) has been used to estimate the environmental impacts in terms of acidification, eutrophication, global climate change, ozone depletion, human health criteria, photochemical smog formation, ecotoxicity, human health cancer, and human health noncancer caused by 1 MJ biofuel production. Taking account of all the indirect greenhouse gas (GHG) emissions, the net GHG emissions (81.8 g CO 2 eq/MJ) of the biofuels are still less than those of petroleum-based fuels (94 g CO 2 eq/MJ). Maize production and pyrolysis and hydroprocessing make major contributions to all impact categories except the human health criteria. All impact categories resulting from indirect emissions except eutrophication and smog air make more than 24% contribution to the total environmental impacts. Therefore, the indirect emissions are important and cannot be ignored. Sensitivity analysis has shown that corn stover yield and bio-oil yield affect the total environmental impacts of the biofuels

RBP-J-interacting and tubulin-associated protein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma by activating the p53–Fbxw7 pathway

International Nuclear Information System (INIS)

Wang, Haihe; Yang, Zhanchun; Liu, Chunbo; Huang, Shishun; Wang, Hongzhi; Chen, Yingli; Chen, Guofu

2014-01-01

Highlights: • RITA overexpression increased protein expression of p53 and Fbxw7 and downregulated the expression of cyclin D1, cyclin E, CDK2, Hes-1 and NF-κB p65. • RITA can significantly inhibit the in vitro growth of SMMC7721 and HepG2 cells. • RITA exerts tumor-suppressive effects in hepatocarcinogenesis through induction of G0/G1 cell cycle arrest and apoptosis and suggest a therapeutic application of RITA in HCC. - Abstract: Aberrant Notch signaling is observed in human hepatocellular carcinoma (HCC) and has been associated with the modulation of cell growth. However, the role of Notch signaling in HCC and its underlying mechanism remain elusive. RBP-J-interacting and tubulin-associated (RITA) mediates the nuclear export of RBP-J to tubulin fibers and downregulates Notch-mediated transcription. In this study, we found that RITA overexpression increased protein expression of p53 and Fbxw7 and downregulated the expression of cyclin D1, cyclin E, CDK2, Hes-1 and NF-κB p65. These changes led to growth inhibition and induced G0/G1 cell cycle arrest and apoptosis in SMMC7721 and HepG2 cells. Our findings indicate that RITA exerts tumor-suppressive effects in hepatocarcinogenesis through induction of G0/G1 cell cycle arrest and apoptosis and suggest a therapeutic application of RITA in HCC

2018-04-26T10:08:58Z https://www.ajol.info/index.php/index/oai oai ...

African Journals Online (AJOL)

article/48213 2018-04-26T10:08:58Z dai:ART Forest Management for Non-Wood Forest Products and Services in Sub-Saharan Africa Chikamai, B Tchatat, M Tieguhong, J Ndoye, O Non-Wood Forest Products, Sustainable Forest Management ...

CDK11{sup p58} represses vitamin D receptor-mediated transcriptional activation through promoting its ubiquitin-proteasome degradation

Energy Technology Data Exchange (ETDEWEB)

Chi, Yayun; Hong, Yi; Zong, Hongliang; Wang, Yanlin; Zou, Weiying; Yang, Junwu; Kong, Xiangfei; Yun, Xiaojing [Gene Research Center, Shanghai Medical College and Institutes of Biomedical, Shanghai 200032 (China); Gu, Jianxin, E-mail: jxgu@shmu.edu.cn [Gene Research Center, Shanghai Medical College and Institutes of Biomedical, Shanghai 200032 (China)

2009-08-28

Vitamin D receptor (VDR) is a member of the nuclear receptor superfamily and regulates transcription of target genes. In this study, we identified CDK11{sup p58} as a novel protein involved in the regulation of VDR. CDK11{sup p58}, a member of the large family of p34cdc2-related kinases, is associated with cell cycle progression, tumorigenesis, and apoptotic signaling. Our study demonstrated that CDK11{sup p58} interacted with VDR and repressed VDR-dependent transcriptional activation. Furthermore, overexpression of CDK11{sup p58} decreased the stability of VDR through promoting its ubiquitin-proteasome-mediated degradation. Taken together, these results suggest that CDK11{sup p58} is involved in the negative regulation of VDR.

Effect of cycle coupling-configuration on energy cascade utilization for a new power and cooling cogeneration cycle

International Nuclear Information System (INIS)

Jing, Xuye; Zheng, Danxing

2014-01-01

Highlights: • A new power and cooling cogeneration cycle was proposed. • The thermophysical properties and the performance of the new cycle were calculated. • Different cycle coupling-configurations were analyzed. • The energy efficiency boosting mechanism of the new cycle was elucidated. - Abstract: To recover mid-low grade heat, a new power/cooling cogeneration cycle was proposed by combining the Kalina cycle and the double-effect ammonia–water absorption refrigeration (DAAR) cycle together, and the equivalent heat-to-power and exergy efficiencies of the cogeneration cycle reached 41.18% and 58.00%, respectively. To determine the effect of cycle coupling-configuration on energy cascade utilization for the new cycle, the cycle coupling-configuration of the Kalina and DAAR cycles were first analyzed, after which the cycle coupling-configuration of the new cycle was analyzed. Analysis results showed that the cycle coupling-configuration of the new cycle enhanced the energy cascade utilization. Furthermore, the energy efficiency boosting mechanism of the new cycle was elucidated

Fatigue during maximal sprint cycling: unique role of cumulative contraction cycles.

Science.gov (United States)

Tomas, Aleksandar; Ross, Emma Z; Martin, James C

2010-07-01

Maximal cycling power has been reported to decrease more rapidly when performed with increased pedaling rates. Increasing pedaling rate imposes two constraints on the neuromuscular system: 1) decreased time for muscle excitation and relaxation and 2) increased muscle shortening velocity. Using two crank lengths allows the effects of time and shortening velocity to be evaluated separately. We conducted this investigation to determine whether the time available for excitation and relaxation or the muscle shortening velocity was mainly responsible for the increased rate of fatigue previously observed with increased pedaling rates and to evaluate the influence of other possible fatiguing constraints. Seven trained cyclists performed 30-s maximal isokinetic cycling trials using two crank lengths: 120 and 220 mm. Pedaling rate was optimized for maximum power for each crank length: 135 rpm for the 120-mm cranks (1.7 m x s(-1) pedal speed) and 109 rpm for the 220-mm cranks (2.5 m x s(-1) pedal speed). Power was recorded with an SRM power meter. Crank length did not affect peak power: 999 +/- 276 W for the 120-mm crank versus 1001 +/- 289 W for the 220-mm crank. Fatigue index was greater (58.6% +/- 3.7% vs 52.4% +/- 4.8%, P < 0.01), and total work was less (20.0 +/- 1.8 vs 21.4 +/- 2.0 kJ, P < 0.01) with the higher pedaling rate-shorter crank condition. Regression analyses indicated that the power for the two conditions was most highly related to cumulative work (r2 = 0.94) and to cumulative cycles (r2 = 0.99). These results support previous findings and confirm that pedaling rate, rather than pedal speed, was the main factor influencing fatigue. Our novel result was that power decreased by a similar increment with each crank revolution for the two conditions, indicating that each maximal muscular contraction induced a similar amount of fatigue.

INTERSTELLAR EXTINCTION LAW TOWARD THE GALACTIC CENTER III: J, H, KS BANDS IN THE 2MASS AND THE MKO SYSTEMS, AND 3.6, 4.5, 5.8, 8.0 μm IN THE SPITZER/IRAC SYSTEM

International Nuclear Information System (INIS)

Nishiyama, Shogo; Nagata, Tetsuya; Tamura, Motohide; Hatano, Hirofumi; Kato, Daisuke; Tanabe, Toshihiko; Sugitani, Koji

2009-01-01

We have determined interstellar extinction law toward the Galactic center (GC) at the wavelength from 1.2 to 8.0 μm, using point sources detected in the IRSF/SIRIUS near-infrared (NIR) survey and those in the Two Micron All Sky Survey (2MASS) and Spitzer/IRAC/GLIMPSE II catalogs. The central region |l | ∼ 0 0 and |b | ∼ 0 0 has been surveyed in the J, H, and K S bands with the IRSF telescope and the SIRIUS camera whose filters are similar to the Mauna Kea Observatories (MKO) NIR photometric system. Combined with the GLIMPSE II point source catalog, we made K S versus K S - λ color-magnitude diagrams (CMDs) where λ=3.6, 4.5, 5.8, and 8.0 μm. The K S magnitudes of bulge red clump stars and the K S - λ colors of red giant branches are used as a tracer of the reddening vector in the CMDs. From these magnitudes and colors, we have obtained the ratios of total-to-selective extinction A K S /E K S -λ for the four IRAC bands. Combined with A λ /A K S for the J and H bands derived by Nishiyama et al., we obtain A J :A H :A K S :A [3.6] :A [4.5] :A [5.8] :A [8.0] = 3.02:1.73:1:0.50:0.39:0.36:0.43 for the line of sight toward the GC. This confirms the flattening of the extinction curve at λ ∼> 3 μm from a simple extrapolation of the power-law extinction at shorter wavelengths, in accordance with recent studies. The extinction law in the 2MASS J, H, and K S bands has also been calculated, and good agreement with that in the MKO system is found. Thus, it is established that the extinction in the wavelength range of J, H, and K S is well fitted by a power law of steep decrease A λ ∝ λ -2.0 toward the GC. In nearby molecular clouds and diffuse interstellar medium, the lack of reliable measurements of the total-to-selective extinction ratios hampers unambiguous determination of the extinction law; however, observational results toward these lines of sight cannot be reconciled with a single extinction law.

7 CFR 58.936 - Milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Milk. 58.936 Section 58.936 Agriculture Regulations of... Official Identification § 58.936 Milk. To process and package evaporated and condensed milk of ultra... Shield the raw incoming milk shall meet the requirements as outlined in §§ 58.132 through 58.136. Unless...

Comparison of stabilities in translucency, fluorescence and opalescence of direct and indirect composite resins.

Science.gov (United States)

Yu, Bin; Lee, Young-Keun

2013-01-01

To evaluate translucency, fluorescence and opalescence stabilities of direct and indirect composite resins after aging. One direct (16 shades) and two indirect composite resins (16 and 26 shades) were investigated. Resins were filled in a mold (1 mm thick) and light cured; post-curings were performed for indirect resins. Color was measured before and after 5,000 cycles of thermocycling on a reflection spectrophotometer in reflectance and transmittance modes to calculate parameters for translucency (TP), fluorescence (FL) and opalescence (OP). Differences in the changes of TP, FL and OP after aging by the type of resin were determined by t test, and those were also determined by one-way ANOVA with the factor of the brand or the shade group (P resins; and were -2.0 to 1.8, -0.9 to 0.4 and -2.9 to 3.7, respectively, for indirect resins. Changes in TP were not significantly different by the type of resin, but those in FL and OP were different (P = 0.05). Changes in optical parameters were influenced by the brand or the shade group of the resins (P resins varied depending on type, brand or shade group. Aging significantly affected fluorescence and opalescence, but not translucency, of indirect resins compared to those of direct resins.

Indirect Effects of Extracurricular Participation on Academic Adjustment via Perceived Friends’ Prosocial Norms

Science.gov (United States)

Hughes, Jan N.; Cao, Qian; Kwok, Oi-man

2016-01-01

Students who participate in extracurricular activities in middle school exhibit higher levels of academic motivation and achievement, including graduation from high school. However, the mechanisms responsible for these beneficial effects are poorly understood. Guided by the bioecological models of development, this study tested the indirect effects of participation in grade 8 in school sports or performance arts and clubs on grade 9 academic achievement, academic competence beliefs, and school belonging, via adolescents’ perceptions of their friends’ prosocial norms. Participants were 495 (45% female) ethnically diverse students (mean age at grade 8 = 13.9 years; SD =.58) who were recruited into a longitudinal study on the basis of below average literacy in grade 1. Using weighted propensity score analyses to control for potential confounders, results of longitudinal SEM found indirect effect of participation in sports, but not of participation in performance arts and clubs, on grade 9 outcomes noted above. Implications of findings for improving educational attainment of at-risk youth are discussed. PMID:27299761

Clinical e radiographic sucess of indirect pulp capping with partial excavation of demineralization dentin in primary posterior teeth

Directory of Open Access Journals (Sweden)

Roberta Francisca Martins de Castro

2009-10-01

Full Text Available Objective: To assess the outcome of the indirect pulp capping technique after incomplete excavation of the demineralized dentin in primary molars of patients treated in the period from 2004 to 2006.Methods: Sample consisted of 81 teeth of 36 patients aged from 1-to-8 year-old. Clinical and radiographic inclusion criteria, as well as criteria of the success of the evaluated treatments were established.Results: There were four (4.9% failures and 77 (95.1% successful treatments. Treatment failure occurred in three girls and in one boy, and no statistically significant difference (p=0.341 was found. Twenty three teeth were treated with resin-modified glass-ionomer cement and 58 with composite resin, of which 22 and 55, respectively, showed successful results. There was no statistically significant difference between restorative materials used (p=0.877. As regards the studied age group, patients aged from 1 to 4 years showed a significantly lower success rate when compared with 5-8 year-old children (p = 0.0428. Conclusion: The results suggest that the indirect pulp capping technique after incomplete excavation of demineralized dentin is a reliable technique to be adopted in deep lesions of primary teeth.

78 FR 24192 - J.P. Morgan Ventures Energy Corp. v. Midwest Independent System Operator, Inc. PJM...

Science.gov (United States)

2013-04-24

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL13-58-000] J.P. Morgan Ventures Energy Corp. v. Midwest Independent System Operator, Inc. PJM Interconnection, L.L.C.; Notice of Complaint Take notice that on April 10, 2013, J.P. Morgan Ventures Energy Corporation (JPMVEC or Complainant...

Dominant spin-flip effects for the hadronic-produced J/ψ polarization at the Tevatron

International Nuclear Information System (INIS)

Wu Xinggang; Fang Zhenyun

2009-01-01

Dominant spin-flip effects for the direct and prompt J/ψ polarizations at Tevatron run II with collision energy 1.96 TeV and rapidity cut |y J/ψ | 8 [ 3 S 1 ] into J/ψ is especially discussed with care. It is found that the spin-flip effect shall always dilute the J/ψ polarization, and with a suitable choice of the parameters a 0,1 and c 0,1,2 , the J/ψ polarization puzzle can be solved to a certain degree. At large transverse momentum p t , α for the prompt J/ψ is reduced by ∼50% for f 0 =v 2 and by ∼80% for f 0 =1. We also study the indirect J/ψ polarization from the b decays, which however is slightly affected by the same spin-flip effect and then shall provide a better platform to determine the color-octet matrix elements.

Effect of Gaseous Impurities on Long-Term Thermal Cycling and Aging Properties of Complex Hydrides for Hydrogen Storage

Energy Technology Data Exchange (ETDEWEB)

Chandra, Dhanesh [Primary Contact; Lamb, Joshua; Chien, Wen-Ming; Talekar, Anjali; and Pal, Narendra

2011-03-28

This program was dedicated to understanding the effect of impurities on Long-Term Thermal Cycling and aging properties of Complex Hydrides for Hydrogen Storage. At the start of the program we found reversibility between Li2NH+LiH LiH+LiNH2 (yielding ~5.8 wt.%H capacity). Then we tested the effect of impurity in H2 gas by pressure cycling at 255°C; first with industrial gas containing ppm levels of O2 and H2O as major impurities. Both these impurities had a significant impact on the reversibility and decreased the capacity by 2.65 wt.%H. Further increase in number of cycles from 500 to 1100 showed only a 0.2 wt%H more weight loss, showing some capacity is still maintained after a significant number of cycles. The loss of capacity is attributed to the formation of ~55 wt% LiH and ~30% Li2O, as major contaminant phases, along with the hydride Li2NH phase; suggesting loss of nitrogen during cycling. The effect of 100 ppm H2O in H2 also showed a decrease of ~2.5 wt.%H (after 560 cycles), and 100ppm O2 in H2; a loss of ~4.1 wt.%. Methane impurity (100 ppm, 100cycles), showed a very small capacity loss of 0.9 wt.%H under similar conditions. However, when Li3N was pressure cycled with 100ppmN2-H2 there were beneficial effects were observed (255oC); the reversible capacity increased to 8.4wt.%H after 853 cycles. Furthermore, with 20 mol.%N2-H2 capacity increased to ~10 wt.%H after 516 cycles. We attribute this enhancement to the reaction of nitrogen with liquid lithium during cycling as the Gibbs free energy of formation of Li3N (Go = -98.7 kJ/mol) is more negative than that of LiH (Go = -50.3 kJ/mol). We propose that the mitigation of hydrogen capacity losses is due to the destabilization of the LiH phase that tends to accumulate during cycling. Also more Li2NH phase was found in the cycled product. Mixed Alanates (3LiNH2:Li3AlH6) showed that 7 wt% hydrogen desorbed under dynamic vacuum. Equilibrium experiments (maximum 12 bar H2) showed up to 4wt% hydrogen reversibly

Partner Choice Drives the Evolution of Cooperation via Indirect Reciprocity.

Directory of Open Access Journals (Sweden)

Gilbert Roberts

Full Text Available Indirect reciprocity potentially provides an important means for generating cooperation based on helping those who help others. However, the use of 'image scores' to summarize individuals' past behaviour presents a dilemma: individuals withholding help from those of low image score harm their own reputation, yet giving to defectors erodes cooperation. Explaining how indirect reciprocity could evolve has therefore remained problematic. In all previous treatments of indirect reciprocity, individuals are assigned potential recipients and decide whether to cooperate or defect based on their reputation. A second way of achieving discrimination is through partner choice, which should enable individuals to avoid defectors. Here, I develop a model in which individuals choose to donate to anyone within their group, or to none. Whereas image scoring with random pairing produces cycles of cooperation and defection, with partner choice there is almost maximal cooperation. In contrast to image scoring with random pairing, partner choice results in almost perfect contingency, producing the correlation between giving and receiving required for cooperation. In this way, partner choice facilitates much higher and more stable levels of cooperation through image scoring than previously reported and provides a simple mechanism through which systems of helping those who help others can work.

Thermodynamic Analysis of Supplementary-Fired Gas Turbine Cycles

DEFF Research Database (Denmark)

Elmegaard, Brian; Henriksen, Ulrik Birk; Qvale, Einar Bjørn

2002-01-01

This paper presents an analysis of the possibilities for improving the efficiency of an indirectly biomass-fired gas turbine (IBFGT) by supplementary direct gas-firing. The supplementary firing may be based on natural gas, biogas, or pyrolysis gas. {The interest in this cycle arise from a recent...... demonstration of a two-stage gasification process through construction of several plants.} A preliminary analysis of the ideal recuperated Brayton cycle shows that for this cycle any supplementary firing will have a marginal efficiency of unity per extra unit of fuel. The same result is obtained...

Effect of a moderate caffeine dose on endurance cycle performance and thermoregulation during prolonged exercise in the heat.

Science.gov (United States)

Beaumont, Ross E; James, Lewis J

2017-11-01

This study investigated the influence of a moderate caffeine dose on endurance cycle performance and thermoregulation during prolonged exercise in high ambient temperature. Double-blind cross-over study. Eight healthy, recreationally active males (mean±SD; age: 22±1 years; body mass: 71.1±8.5kg; VO 2peak : 55.9±5.8mLkg -1 min -1 ; W max : 318±37W) completed one VO 2peak test, one familiarisation trial and two experimental trials. After an overnight fast, participants ingested a placebo or a 6mgkg -1 caffeine dose 60min before exercise. The exercise protocol consisted of 60min of cycle exercise at 55% W max , followed by a 30min performance task (total kJ produced) in 30°C and 50% RH. Performance was enhanced (Cohen's d effect size=0.22) in the caffeine trial (363.8±47.6kJ) compared with placebo (353.0±49.0kJ; p=0.004). Caffeine did not influence core (p=0.188) or skin temperature (p=0.577) during exercise. Circulating prolactin (p=0.572), cortisol (p=0.842) and the estimated rates of fat (p=0.722) and carbohydrate oxidation (p=0.454) were also similar between trial conditions. Caffeine attenuated perceived exertion during the initial 60min of exercise (p=0.033), with no difference in thermal stress across trials (p=0.911). Supplementation with 6mgkg -1 caffeine improved endurance cycle performance in a warm environment, without differentially influencing thermoregulation during prolonged exercise at a fixed work-rate versus placebo. Therefore, moderate caffeine doses which typically enhance performance in temperate environmental conditions also appear to benefit endurance performance in the heat. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Cruel intentions on television and in real life: can viewing indirect aggression increase viewers' subsequent indirect aggression?

Science.gov (United States)

Coyne, Sarah M; Archer, John; Eslea, Mike

2004-07-01

Numerous studies have shown that viewing violence in the media can influence an individual's subsequent aggression, but none have examined the effect of viewing indirect aggression. This study examines the immediate effect of viewing indirect and direct aggression on subsequent indirect aggression among 199 children ages 11 to 14 years. They were shown an indirect, direct, or no-aggression video and their subsequent indirect aggression was measured by negative evaluation of a confederate and responses to a vignette. Participants viewing indirect or direct aggression gave a more negative evaluation of and less money to a confederate than participants viewing no-aggression. Participants viewing indirect aggression gave less money to the confederate than those viewing direct aggression. Participants viewing indirect aggression gave more indirectly aggressive responses to an ambiguous situation and participants viewing direct aggression gave more directly aggressive responses. This study provides the first evidence that viewing indirect aggression in the media can have an immediate impact on subsequent aggression.

7 CFR 58.932 - Milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Milk. 58.932 Section 58.932 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....932 Milk. The raw milk shall meet the requirements as outlined in §§ 58.132 through 58.138. Unless...

7 CFR 58.232 - Milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Milk. 58.232 Section 58.232 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....232 Milk. Raw milk shall meet the requirements as outlined in §§ 58.132 through 58.138 and, unless...

Comparison of desiccant air conditioning systems with different indirect evaporative air coolers

International Nuclear Information System (INIS)

Pandelidis, Demis; Anisimov, Sergey; Worek, William M.; Drąg, Paweł

2016-01-01

Highlights: • A numerical study of desiccant air conditioning systems is presented. • The ε-NTU model is used for the analysis. • Different arrangements of the desiccant systems were compared. • The systems were compared under different operating conditions. - Abstract: This paper presents a numerical analysis of three desiccant air-conditioning systems equipped with different indirect evaporative air coolers: (1) the cross-flow Maisotsenko cycle heat and mass exchanger (HMX), (2) the regenerative counter-flow Maisotsenko cycle heat and mass exchanger and (3) the standard cross-flow evaporative air cooler. To analyze the desiccant wheel and the indirect evaporative air coolers, the modified ε-NTU-model was used. The simulations were performed under assumption that the desiccant wheel is regenerated with air heated to relatively low temperature values (50–60 °C), which can be produced with solar panels in typical moderate climatic conditions. It was established that the main advantage of the presented solutions is that they can provide comfort conditions even with less effective dehumidification. The different systems were compared under variable selected operational factors (i.e. inlet air temperature, humidity and regeneration air temperature). The analysis allowed establishing the advantages and disadvantages of presented solutions and allowed estimating their application potential.

7 CFR 58.430 - Milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Milk. 58.430 Section 58.430 Agriculture Regulations of....430 Milk. The milk shall be fresh, sweet, pleasing and desirable in flavor and shall meet the requirements as outlined under §§ 58.132 through 58.138. The milk may be adjusted by separating part of the fat...

RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription.

Science.gov (United States)

Yang, Chuan-Pin; Kuo, Yu-Liang; Lee, Yi-Chao; Lee, Kuen-Haur; Chiang, Chi-Wu; Wang, Ju-Ming; Hsu, Che-Chia; Chang, Wen-Chang; Lin, Ding-Yen

2016-09-16

The nucleolus is the cellular site of ribosomal (r)DNA transcription and ribosome biogenesis. The 58-kDa microspherule protein (MSP58) is a nucleolar protein involved in rDNA transcription and cell proliferation. However, regulation of MSP58-mediated rDNA transcription remains unknown. Using a yeast two-hybrid system with MSP58 as bait, we isolated complementary (c)DNA encoding Rad50-interacting protein 1 (RINT-1), as a MSP58-binding protein. RINT-1 was implicated in the cell cycle checkpoint, membrane trafficking, Golgi apparatus and centrosome dynamic integrity, and telomere length control. Both in vitro and in vivo interaction assays showed that MSP58 directly interacts with RINT-1. Interestingly, microscopic studies revealed the co-localization of MSP58, RINT-1, and the upstream binding factor (UBF), a rRNA transcription factor, in the nucleolus. We showed that ectopic expression of MSP58 or RINT-1 resulted in decreased rRNA expression and rDNA promoter activity, whereas knockdown of MSP58 or RINT-1 by siRNA exerted the opposite effect. Coexpression of MSP58 and RINT-1 robustly decreased rRNA synthesis compared to overexpression of either protein alone, whereas depletion of RINT-1 from MSP58-transfected cells enhanced rRNA synthesis. We also found that MSP58, RINT-1, and the UBF were associated with the rDNA promoter using a chromatin immunoprecipitation assay. Because aberrant ribosome biogenesis contributes to neoplastic transformation, our results revealed a novel protein complex involved in the regulation of rRNA gene expression, suggesting a role for MSP58 and RINT-1 in cancer development. Copyright © 2016 Elsevier Inc. All rights reserved.

Effect of the weld thermal cycles by the modified indirect electric arc (MIEA) on the mechanical properties of the AA6061-T6 alloy

International Nuclear Information System (INIS)

Ambriz, R. A.; Barrera, G.; Garcia, R.; Lopez, V. H.

2009-01-01

Results of temperature measurements during welding of 12.7 mm thick AA6061-T6 alloy plates by modified indirect electric arc (MIEA) are presented. This study describes the thermal cycles of the heat affected zone (HAZ) and also in the fusion zone. Depending upon the position of the transducers, the maximum temperatures measured in the HAZ range from 308 to 693 degree centigrade, these measurements were related with the tensile test results, and the failure zone reported previously by the authors. It was observed that, there is a decrease in the mechanical strength of the welded joints, due to the microstructural changes suffered by AA6061-T6 alloy in which formation of the βoccurs according to the TTT transformation diagram. The inherent cooling conditions of the weld pool observed for the MIEA technique (only one pass of welding), have permitted to establish the characteristics of solidification and microstructure for a specific cooling rate. (Author) 24 refs

Neutron enrichment at midrapidity in 58Ni + 58Ni at 52 MeV/u

International Nuclear Information System (INIS)

Theriault, D.; Vallee, A.; Gingras, L.; Larochelle, Y.; Roy, R.; April, A.; Beaulieu, L.; Grenier, F.; Lemieux, F.; Moisan, J.; Samri, M.; Saint-Pierre, C.; Turbide, S.; Yennello, S.J.; Martin, E.; Winchester, E.

2003-01-01

By combining data from a charged particle 58 Ni + 58 Ni experiment at 52 MeV/u with an 36 Ar + 58 Ni experiment at 50 MeV/u for which free neutrons have been detected, an increase in the neutron to proton ratio of the whole nuclear material at midrapidity has been experimentally observed in the reaction 58 Ni + 58 Ni at 52 MeV/u. The neutron to proton ratio is measured above the initial neutron to proton ratio of the system. Neutron to proton ratio of the quasi-projectile emission is analysed for the same reactions and is seen to decrease below the ratio of the initial system. (authors)

Indirect taxation in the European Union

OpenAIRE

Ene, Sebastian; Micuda, Dan

2007-01-01

Indirect taxes are levied on the production and consumption of goods and services. They influence the retail price, and hence affect patterns of trade and consumption. Indirect taxes are ultimately paid by the final consumer. Sales and turnover taxes, excise duties and tariffs are the basic indirect taxes. In contrast with direct taxes, indirect taxes are seldom progressive. The principles for the levying of these taxes will be considered before the analysis of indirect taxes.

Suggestions for future Pu fuel cycle designs

International Nuclear Information System (INIS)

Serfontein, Dawid E.; Mulder, Eben J.; Reitsma, Frederik

2013-01-01

Recommended follow-up Pu Studies: • Verification of VSOP-A vs. VSOP 99/05, by comparison with MCNP. • DLOFC temperatures with Multi-group Tinte. • Redesign of the reactor: - Replace small concentrated Pu fuel kernels with large (500 μm diameter) diluted kernels to reduce burn-up. - Switch from the direct Brayton cycle to the indirect Rankine steam cycle to reduce fuel temperatures. - Add neutron poisons to the reflectors to suppress power and temperature peaks and to produce negative uniform temperature reactivity coefficients

Partitioning of late gestation energy expenditure in ewes using indirect calorimetry and a linear regression approach

DEFF Research Database (Denmark)

Kiani, Alishir; Chwalibog, André; Nielsen, Mette O

2007-01-01

Late gestation energy expenditure (EE(gest)) originates from energy expenditure (EE) of development of conceptus (EE(conceptus)) and EE of homeorhetic adaptation of metabolism (EE(homeorhetic)). Even though EE(gest) is relatively easy to quantify, its partitioning is problematic. In the present...... study metabolizable energy (ME) intake ranges for twin-bearing ewes were 220-440, 350- 700, 350-900 kJ per metabolic body weight (W0.75) at week seven, five, two pre-partum respectively. Indirect calorimetry and a linear regression approach were used to quantify EE(gest) and then partition to EE......(conceptus) and EE(homeorhetic). Energy expenditure of basal metabolism of the non-gravid tissues (EE(bmng)), derived from the intercept of the linear regression equation of retained energy [kJ/W0.75] and ME intake [kJ/W(0.75)], was 298 [kJ/ W0.75]. Values of the intercepts of the regression equations at week seven...

Bile acids cycle disruption in patients with nasopharyngeal ...

African Journals Online (AJOL)

2014-12-31

Dec 31, 2014 ... Cite as: Wang C-S, Liu S-H, Peng J, Tang C, Zhu W-G. Bile acids cycle disruption in patients .... stein-Barr virus in the development of nasopharyngeal carcinoma. Chin. J. Cancer 2014; 33(11): 556 PubMed. -568. 2. Mrizak D, Martin N, Barjon C, Jimenez-Pailhes AS,. Mustapha R, Niki T, Guigay J, Pancre V, ...

7 CFR 58.636 - Homogenization.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Homogenization. 58.636 Section 58.636 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Procedures § 58.636 Homogenization. Homogenization of the pasteurized mix shall be accomplished to...

A fuel management study and cycle nuclear design for PW reactors

International Nuclear Information System (INIS)

Minguez, E.; Ahnert, C.; Aragones, J. M.; Corella, M. R.

1975-01-01

A reference reactor was chosen to do a general study involving Fuel Management Evaluations of several cycles, and Design Calculations of cycles already performed, according to a calculation scheme set up in the Reactor Technology Division of the J.E.N., using some computer codes acquired to foreign sources and other ones developed in the J.E.N. (Author) 5 refs

A fuel management study and cycle nuclear design for PW reactors

Energy Technology Data Exchange (ETDEWEB)

Minguez, E; Ahnert, C; Aragones, J M; Corella, M R

1975-07-01

A reference reactor was chosen to do a general study involving Fuel Management Evaluations of several cycles, and Design Calculations of cycles already performed, according to a calculation scheme set up in the Reactor Technology Division of the J.E.N., using some computer codes acquired to foreign sources and other ones developed in the J.E.N. (Author) 5 refs.

RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription

International Nuclear Information System (INIS)

Yang, Chuan-Pin; Kuo, Yu-Liang; Lee, Yi-Chao; Lee, Kuen-Haur; Chiang, Chi-Wu; Wang, Ju-Ming; Hsu, Che-Chia

2016-01-01

The nucleolus is the cellular site of ribosomal (r)DNA transcription and ribosome biogenesis. The 58-kDa microspherule protein (MSP58) is a nucleolar protein involved in rDNA transcription and cell proliferation. However, regulation of MSP58-mediated rDNA transcription remains unknown. Using a yeast two-hybrid system with MSP58 as bait, we isolated complementary (c)DNA encoding Rad50-interacting protein 1 (RINT-1), as a MSP58-binding protein. RINT-1 was implicated in the cell cycle checkpoint, membrane trafficking, Golgi apparatus and centrosome dynamic integrity, and telomere length control. Both in vitro and in vivo interaction assays showed that MSP58 directly interacts with RINT-1. Interestingly, microscopic studies revealed the co-localization of MSP58, RINT-1, and the upstream binding factor (UBF), a rRNA transcription factor, in the nucleolus. We showed that ectopic expression of MSP58 or RINT-1 resulted in decreased rRNA expression and rDNA promoter activity, whereas knockdown of MSP58 or RINT-1 by siRNA exerted the opposite effect. Coexpression of MSP58 and RINT-1 robustly decreased rRNA synthesis compared to overexpression of either protein alone, whereas depletion of RINT-1 from MSP58-transfected cells enhanced rRNA synthesis. We also found that MSP58, RINT-1, and the UBF were associated with the rDNA promoter using a chromatin immunoprecipitation assay. Because aberrant ribosome biogenesis contributes to neoplastic transformation, our results revealed a novel protein complex involved in the regulation of rRNA gene expression, suggesting a role for MSP58 and RINT-1 in cancer development. - Highlights: • RINT-1 is a novel MSP58-interacting protein. • RINT-1 is a nucleolar protein that suppresses ribosomal RNA gene transcription. • RINT-1 and MSP58 cooperate to suppress ribosomal RNA gene transcription. • RINT-1, MSP58, and UBF form a complex on the rDNA promoter.

7 CFR 58.3 - Authority.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Authority. 58.3 Section 58.3 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections... Inspection and Grading Services of Manufactured or Processed Dairy Products Administration § 58.3 Authority...

7 CFR 58.920 - Homogenization.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Homogenization. 58.920 Section 58.920 Agriculture... Procedures § 58.920 Homogenization. Where applicable concentrated products shall be homogenized for the... homogenization and the pressure at which homogenization is accomplished will be that which accomplishes the most...

7 CFR 58.640 - Packaging.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging. 58.640 Section 58.640 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Procedures § 58.640 Packaging. The packaging of the semifrozen product shall be done by means which will in...

28 CFR 90.58 - Evaluation.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Evaluation. 90.58 Section 90.58 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) VIOLENCE AGAINST WOMEN Indian Tribal Governments Discretionary Program § 90.58 Evaluation. The National Institute of Justice will conduct an evaluation of these programs. ...

7 CFR 58.334 - Pasteurization.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Pasteurization. 58.334 Section 58.334 Agriculture... Procedures § 58.334 Pasteurization. The milk or cream shall be pasteurized at the plant where the milk or... adequate pasteurization. Additional heat treatment above the minimum pasteurization requirement is...

Parametric Investigation of Brayton Cycle for High Temperature Gas-Cooled Reactor

International Nuclear Information System (INIS)

Chang Oh

2004-01-01

The Idaho National Engineering and Environmental Laboratory (INEEL) is investigating a Brayton cycle efficiency improvement on a high temperature gas-cooled reactor (HTGR) as part of Generation-IV nuclear engineering research initiative. In this project, we are investigating helium Brayton cycles for the secondary side of an indirect energy conversion system. Ultimately we will investigate the improvement of the Brayton cycle using other fluids, such as supercritical carbon dioxide. Prior to the cycle improvement study, we established a number of baseline cases for the helium indirect Brayton cycle. These cases look at both single-shaft and multiple-shaft turbomachinery. The baseline cases are based on a 250 MW thermal pebble bed HTGR. The results from this study are applicable to other reactor concepts such as a very high temperature gas-cooled reactor (VHTR), fast gas-cooled reactor (FGR), supercritical water reactor (SWR), and others. In this study, we are using the HYSYS computer code for optimization of the helium Brayton cycle. Besides the HYSYS process optimization, we performed parametric study to see the effect of important parameters on the cycle efficiency. For these parametric calculations, we use a cycle efficiency model that was developed based on the Visual Basic computer language. As a part of this study we are currently investigated single-shaft vs. multiple shaft arrangement for cycle efficiency and comparison, which will be published in the next paper. The ultimate goal of this study is to use supercritical carbon dioxide for the HTGR power conversion loop in order to improve the cycle efficiency to values great than that of the helium Brayton cycle. This paper includes preliminary calculations of the steady state overall Brayton cycle efficiency based on the pebble bed reactor reference design (helium used as the working fluid) and compares those results with an initial calculation of a CO2 Brayton cycle

7 CFR 58.150 - Containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Containers. 58.150 Section 58.150 Agriculture... Identification § 58.150 Containers. (a) The size, style, and type of packaging used for dairy products shall be commercially acceptable containers and packaging materials which will satisfactorily cover and protect the...

7 CFR 58.339 - Containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Containers. 58.339 Section 58.339 Agriculture... Procedures § 58.339 Containers. (a) Containers used for the packaging of butter and related products shall be commercially acceptable containers or packaging material that will satisfactorily protect the quality of the...

7 CFR 58.518 - Milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Milk. 58.518 Section 58.518 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....518 Milk. The selection of raw milk for cottage cheese shall be in accordance with §§ 58.132 through...

Indirect Self-Destructiveness and Emotional Intelligence.

Science.gov (United States)

Tsirigotis, Konstantinos

2016-06-01

While emotional intelligence may have a favourable influence on the life and psychological and social functioning of the individual, indirect self-destructiveness exerts a rather negative influence. The aim of this study has been to explore possible relations between indirect self-destructiveness and emotional intelligence. A population of 260 individuals (130 females and 130 males) aged 20-30 (mean age of 24.5) was studied by using the Polish version of the chronic self-destructiveness scale and INTE, i.e., the Polish version of the assessing emotions scale. Indirect self-destructiveness has significant correlations with all variables of INTE (overall score, factor I, factor II), and these correlations are negative. The intensity of indirect self-destructiveness differentiates significantly the height of the emotional intelligence and vice versa: the height of the emotional intelligence differentiates significantly the intensity of indirect self-destructiveness. Indirect self-destructiveness has negative correlations with emotional intelligence as well as its components: the ability to recognize emotions and the ability to utilize emotions. The height of emotional intelligence differentiates the intensity of indirect self-destructiveness, and vice versa: the intensity of indirect self-destructiveness differentiates the height of emotional intelligence. It seems advisable to use emotional intelligence in the prophylactic and therapeutic work with persons with various types of disorders, especially with the syndrome of indirect self-destructiveness.

A maximal cycle test with good validity and high repeatability in adults of all ages

DEFF Research Database (Denmark)

Eriksen, L; Tolstrup, J S; Larsen, Steen

2014-01-01

indirectly in both tests and measured directly in one test. Agreement between the direct measurement and the indirect estimate of VO2max and repeatability of the indirect estimates of VO2max were examined by Bland-Altman plots, limits of agreement (LOA) and coefficient of repeatability (CR). The indirect...... method (mean VO2max=3 132 ml · min(-1)) underestimated VO2max as compared to the direct method (mean VO2max=3 190 ml · min(-1)) in men (bias: 58 ml · min(-1) (95% LOA-450 and 565)) and overestimated VO2max in women (mean VO2max=2 328 vs. 2 258 ml · min(-1), bias: - 70 ml · min(-1) (95% LOA-468 and 328...

7 CFR 1786.58 - Security.

Science.gov (United States)

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Security. 1786.58 Section 1786.58 Agriculture... Discounted Prepayments on RUS Direct/Insured Loans § 1786.58 Security. If, after prepayment of RUS Notes, the... be, will consider request for the accommodation of such liens for the purpose of providing security...

7 CFR 58.127 - Facilities.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Facilities. 58.127 Section 58.127 Agriculture..., Facilities, Equipment and Utensils § 58.127 Facilities. (a) Water supply. There shall be an ample supply of both hot and cold water of safe and sanitary quality, with adequate facilities for its proper...

7 CFR 58.130 - Health.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Health. 58.130 Section 58.130 Agriculture Regulations... Plants Approved for USDA Inspection and Grading Service 1 Personnel, Cleanliness and Health § 58.130 Health. No person afflicted with a communicable disease shall be permitted in any room or compartment...

Mouse estrous cycle identification tool and images.

Directory of Open Access Journals (Sweden)

Shannon L Byers

Full Text Available The efficiency of producing timed pregnant or pseudopregnant mice can be increased by identifying those in proestrus or estrus. Visual observation of the vagina is the quickest method, requires no special equipment, and is best used when only proestrus or estrus stages need to be identified. Strain to strain differences, especially in coat color can make it difficult to determine the stage of the estrous cycle accurately by visual observation. Presented here are a series of images of the vaginal opening at each stage of the estrous cycle for 3 mouse strains of different coat colors: black (C57BL/6J, agouti (CByB6F1/J and albino (BALB/cByJ. When all 4 stages (proestrus, estrus, metestrus, and diestrus need to be identified, vaginal cytology is regarded as the most accurate method. An identification tool is presented to aid the user in determining the stage of estrous when using vaginal cytology. These images and descriptions are an excellent resource for learning how to determine the stage of the estrous cycle by visual observation or vaginal cytology.

Verticalization of behavior elicited by dopaminergic mobilization is qualitatively different between C57BL/6J and DBA/2J mice.

Science.gov (United States)

Tirelli, E; Witkin, J M

1994-10-01

Behavioral effects of dopaminergic stimulation were evaluated in C57BL/6J mice and compared to the effects occurring in DBA/2J mice, an inbred strain with reduced densities of striatal dopamine receptors. Effects of apomorphine (0.5-64 mg/kg) alone and in combination with cocaine (30 mg/kg) were assessed using a time-sampling technique that classified climbing and leaning in separate categories. Locomotion was also assessed in a separate experiment. Climbing occurred in DBA/2J mice only at doses of apomorphine that were 16 times higher than the smallest effective dose in C57BL/6J mice; nevertheless, relative to baseline values, effects were fairly comparable. By contrast, whereas DBA/2J mice showed dose-dependent leaning under apomorphine, C57BL/6J mice exhibited little leaning even at doses not producing climbing, and only after the highest apomorphine dose was leaning significantly increased. Apomorphine was equipotent in inducing gnawing across strains, although somewhat less efficacious in DBA/2J mice. When given alone, cocaine produced significant climbing, but not leaning or gnawing, in either strain. Whereas cocaine potentiated apomorphine-induced climbing and gnawing in both strains, apomorphine-induced leaning was not consistently changed by cocaine in either strain. These effects were not indirectly due to hyperkinesia, since neither apomorphine alone nor apomorphine and cocaine in combination was stimulant; apomorphine alone reduced locomotor activity and attenuated cocaine-induced hyperkinesia. The present data do not support a unitary, purely quantitative, account of insensitivity to dopaminergic stimulation based upon low densities of striatal dopamine receptors in DBA/2J mice. Rather, this constellation of results is suggestive of qualitative interstrain dissimilarities in dopaminergic responsiveness that could reflect organizational differences in receptor populations.

Final State Interaction Effects on the B + → J / ψ ρ + Decay

Directory of Open Access Journals (Sweden)

Behnam Mohammadi

2012-01-01

Full Text Available The exclusive decay of B + → J / ψ ρ + is studied in the framework of the QCD factorization (QCDF method and final state interaction (FSI. A direct B + → J / ψ ρ + decay is only occurred via a tree and a penguin based on the quark diagram analysis. The result that is found by using the QCDF method is less than the experimental result, so, the role of FSI is considered. The intermediate states D + D ̅ 0 , D + * D ̅ 0 * , D + * D ̅ 0 , and D + D ̅ 0 * via the exchange of D - and D - * are contributed to the B + → J / ψ ρ + decay. The above intermediate states is calculated by using the QCDF method. In the FSI effects the results of our calculations depend on “η” as the phenomenological parameter. The range of this parameter are selected from 1 to 2. For the exchanged particles D - and D - * , it is found that if η = 1.58 ~ 1.83 is selected the numbers of the branching ratio are placed in the experimental range. The experimental branching ratio of B + → J / ψ ρ + decay is ( 5 ± 0.8 × 1 0 - 5 , and our prediction number is ( 1.42 ± 0.36 × 1 0 - 5 in the absence of FSI effects, and it becomes ( 4.2 ~ 5.8 × 1 0 - 5 when FSI contributions are taken into account.

7 CFR 58.432 - Catalase.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Catalase. 58.432 Section 58.432 Agriculture... Material § 58.432 Catalase. The catalase preparation shall be a stable, buffered solution, neutral in pH, having a potency of not less than 100 Keil units per milliliter. The source of the catalase, its...

Recent results of hadronic decays of J/psi into vector-tensor from MARK III

International Nuclear Information System (INIS)

Becker, J.J.; Blaylock, G.T.; Bolton, T.; Brown, J.S.

1987-02-01

From a data sample of 5.8 x 10 6 J/psi's collected by the MARK III detector at the storage ring SPEAR at SLAC, two-body decay modes of the J/psi into a vector and a tensor meson have been measured. From the studies of the tensor meson, recoiling against the ideally mixed and well understood vector mesons, quark correlations are established and compared with the theoretical expectations of the J/psi decays and the SU(3) predictions. The beginnings of a similar systematic study of the two-body vector scalar decays are also presented

Patterns and determinants of business cycle synchronization in the enlarged European Economic and Monetary Union

Directory of Open Access Journals (Sweden)

Iulia SIEDSCHLAG

2010-06-01

Full Text Available This paper provides empirical evidence about the degree of business cycle synchronization between the euro area countries and eight new European Union member states. We analyze the direct and indirect effects of similarity of economic structures and trade intensity on the co-movement of fluctuations of economic activity across these countries and find that bilateral similarity of economic structures and trade intensity were positively and significantly associated with business cycle correlations. This result is robust to different estimation techniques. Similarity of economic structures had an additional indirect positive effect on business cycle synchronization via its positive effect on trade intensity. The bilateral business cycle correlations are found to be endogenous with respect to bilateral similarity of economic structures and bilateral trade intensity suggesting that the new European Union countries will better satisfy the Optimum Currency Area criteria after the adoption of the euro.

7 CFR 58.809 - Pasteurization.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Pasteurization. 58.809 Section 58.809 Agriculture... Procedures § 58.809 Pasteurization. (a) All fluid whey used in the manufacture of dry whey, dry whey products... drying operations for dry whey take place at the same plant, the pasteurization may be located at a...

The diagnostic value of indirect lower limb CT venography in the lower extremity deep venous thrombosis

International Nuclear Information System (INIS)

Zhu Li; Guo Youmin; Wang Jianguo; Guo Xiaojuan; Liu Min; Guo Yulin

2009-01-01

Objective: To evaluate indirect CT venography (CTV) in the diagnosis of deep venous thrombosis (DVT). Methods: A total of 516 acute pulmonary embolism patients proved by objective test were analyzed retrospectively. Using the results of lower limb compression sonography as reference standard, the sensitivity, specificity, positive predictive value and negative predictive value of indirect CTV were calculated. The agreement between lower extremity venous sonography and indirect CTV were assessed by Kappa analysis. Results: Among 516 patients with acute pulmonary thromboembolism (PTE), 110 patients underwent both CTV and CTPA and lower extremity sonography. DVT were detected by CTV and sonography simultaneously in 48 patients, while no DVT was detected in 39 patients by both examinations. Thirteen patients were diagnosed to have DVT by CTV without sonography detection, and DVT was detected in other 10 patients only by sonography. The sensitivity, specificity, positive predictive value and negative predictive value of indirect CTV was 82.8% (48/58), 75.0% (39/52), 78.7% (48/61) and 79.6% (39/49). The agreement between lower extremity venous sonography and indirect CTV was good for femoropopliteal vein (Kappa value range from 0.874 to 0.914, P=0.000). Thrombi detected by CTV were 62 and 52 respectively, and for sonography were 67 and 51 respectively. For calf veins, the agreement decreased (Kappa value range from 0.464 to 0.584, P=0.000). Thrombi detected by CTV were 6, 25 and 13 respectively, and for sonography were 13, 38 and 19 respectively. The agreement for external iliac vein was poor (Kappa value range from 0.230 to 0.262, P=0.067 and 0.004, respectively). Thrombi detected by CTV were 33, and for sonography were 17. Conclusions: The indirect CTV has high accuracy in the diagnosis of DVT. Combined CTPA and CTV can image pulmonary arteries and lower extremity veins in one examination. Indirect CTV can reveal thrombus in large pelvic veins, which has an advantage

Protein nutrient value evaluation of mutant strain J5 fruitbody Agaricus bazei murrill by 60Co γ-irradiation

International Nuclear Information System (INIS)

Weng Boqi; Huang Tingjun

2004-01-01

Protein nutrient value evaluation of mutant strain J 5 fruitbody Agaricus bazei Murrill by 60 Co γ-irradiation was studied. The results showed its total content of amino acids Agaricus bazei murrill was 48.20%; chemical score 58.10; amino acids score 88.60; necessary amino acids index 89.94; biologic value 86.29; nutrient index 29.15. All the index above were higher than that in original strain J 1 , but the ratio score of amino acids of J 5 fruitbody (39.48) was lower than strain J 1 . The results indicated that nutrient value of protein in J 5 was higher than in J 1 . (authors)

Characterization of thermophysical properties of phase change materials for non-membrane based indirect solar desalination application

International Nuclear Information System (INIS)

Sarwar, J.; Mansoor, B.

2016-01-01

Highlights: • Thermal cycling of paraffin waxes phase change materials. • Differential Scanning Calorimetry and thermogravimetric study of the materials. • Characterization of the phase change materials via Temperature History Method. • Investigation of suitability of materials for indirect solar desalination system. • Paraffin waxes are suitable for non-membrane indirect solar desalination system. - Abstract: Phase change material as a thermal energy storage medium has been widely incorporated in various technologies like solar air/water heating, buildings, and desalination for efficient use and management of fluctuating solar energy. Temperature and thermal energy requirements dictate the selection of an appropriate phase change material for its application in various engineering systems. In this work, two phase change materials belonging to organic paraffin wax class have been characterized to obtain their thermophysical properties. The melting/solidification temperatures, latent heat of fusion and heat capacities of the phase change materials have been investigated using Differential Scanning Calorimetry, Thermogravimetric analysis and Temperature History Method. Thermal cycles up to 300 are performed to investigate melting and solidification reversibility as well as degradation over time. It is shown that the selected paraffin waxes have reversible phase change with no degradation of thermophysical properties over time. It is also shown that melting/solidification temperature and thermal energy storage capabilities make them suitable for their application as a thermal energy storage medium, in high temperature vapour compression, multi-stage flash and multi-effect distillation processes of non-membrane based indirect desalination systems.

Cloud Condensation Nuclei Prediction Error from Application of Kohler Theory: Importance for the Aerosol Indirect Effect

Science.gov (United States)

Sotiropoulou, Rafaella-Eleni P.; Nenes, Athanasios; Adams, Peter J.; Seinfeld, John H.

2007-01-01

In situ observations of aerosol and cloud condensation nuclei (CCN) and the GISS GCM Model II' with an online aerosol simulation and explicit aerosol-cloud interactions are used to quantify the uncertainty in radiative forcing and autoconversion rate from application of Kohler theory. Simulations suggest that application of Koehler theory introduces a 10-20% uncertainty in global average indirect forcing and 2-11% uncertainty in autoconversion. Regionally, the uncertainty in indirect forcing ranges between 10-20%, and 5-50% for autoconversion. These results are insensitive to the range of updraft velocity and water vapor uptake coefficient considered. This study suggests that Koehler theory (as implemented in climate models) is not a significant source of uncertainty for aerosol indirect forcing but can be substantial for assessments of aerosol effects on the hydrological cycle in climatically sensitive regions of the globe. This implies that improvements in the representation of GCM subgrid processes and aerosol size distribution will mostly benefit indirect forcing assessments. Predictions of autoconversion, by nature, will be subject to considerable uncertainty; its reduction may require explicit representation of size-resolved aerosol composition and mixing state.

Comment traduire en japonais les styles indirect et indirect libre de Madame Bovary ?

Directory of Open Access Journals (Sweden)

Hisaki Sawasaki

2012-03-01

Full Text Available Parmi les difficultés rencontrées lors de la traduction des textes littéraires occidentaux, en japonais, nous examinons le problème des styles indirect et indirect libre. Pour cela, en effectuant une petite mise au point grammaticale, nous comparons sept traductions de Madame Bovary de Gustave Flaubert, dont les dates de parution s’étendent sur une cinquantaine d’années. Cette période s’apparente, de notre point de vue, à un long itinéraire pour assimiler la notion occidentale des styles direct et indirect, tout en la conciliant avec les particularités du japonais. D’un autre côté, ce travail acharné des traducteurs a influencé quelque peu la langue japonaise. On trouve dans l’annexe tous les textes en japonais examinés.We will examine the difficulties met when translating Western literary texts in Japanese, in particular the problem of indirect and free indirect styles. We will define the grammatical issue and compare seven translations of Madame Bovary, published over a fifty year period. This time can be likened to a long path taken to digest the Western notion of direct and indirect styles, while reconciling it with Japanese language characteristics. On the other hand the translators’ relentless work has somewhat influenced the Japanese language. The annex will present all the Japanese texts examined.

Indirect Energy for Road and Railway Transportation in Sweden; Indirekt energi foer svenska vaeg- och jaernvaegstransporter

Energy Technology Data Exchange (ETDEWEB)

Jonsson, Daniel K.

2005-02-01

Besides energy for propulsion, there are a number of considerable indirect energy categories in the life-cycle of transport systems, e.g. construction and maintenance of infrastructure, and manufacture and service of vehicles. Indirect energy represents 64-66% of the total amount of energy used in the railway sector, while the corresponding share in the road sector is 42-45%. Consequently, decision-making and planning processes regarding transport infrastructure and environmental impacts should also consider indirect energy-use. Two energy case studies have been carried through; the railroad project Botniabanan in the north of Sweden, and the motorway tunnel Soedra Laenken in Stockholm. The result for Botniabanan corresponds with the Swedish railroad average, but Botniabanan contributes to decreased energy use in the transport sector as a whole. The infra structural energy use for Soedra Laenken is considerably higher than the Swedish road average. Soedra Laenken also contributes to an increase of the energy use in the transport sector as a whole.

Broadening the functionality of a J-protein/Hsp70 molecular chaperone system.

Science.gov (United States)

Schilke, Brenda A; Ciesielski, Szymon J; Ziegelhoffer, Thomas; Kamiya, Erina; Tonelli, Marco; Lee, Woonghee; Cornilescu, Gabriel; Hines, Justin K; Markley, John L; Craig, Elizabeth A

2017-10-01

By binding to a multitude of polypeptide substrates, Hsp70-based molecular chaperone systems perform a range of cellular functions. All J-protein co-chaperones play the essential role, via action of their J-domains, of stimulating the ATPase activity of Hsp70, thereby stabilizing its interaction with substrate. In addition, J-proteins drive the functional diversity of Hsp70 chaperone systems through action of regions outside their J-domains. Targeting to specific locations within a cellular compartment and binding of specific substrates for delivery to Hsp70 have been identified as modes of J-protein specialization. To better understand J-protein specialization, we concentrated on Saccharomyces cerevisiae SIS1, which encodes an essential J-protein of the cytosol/nucleus. We selected suppressors that allowed cells lacking SIS1 to form colonies. Substitutions changing single residues in Ydj1, a J-protein, which, like Sis1, partners with Hsp70 Ssa1, were isolated. These gain-of-function substitutions were located at the end of the J-domain, suggesting that suppression was connected to interaction with its partner Hsp70, rather than substrate binding or subcellular localization. Reasoning that, if YDJ1 suppressors affect Ssa1 function, substitutions in Hsp70 itself might also be able to overcome the cellular requirement for Sis1, we carried out a selection for SSA1 suppressor mutations. Suppressing substitutions were isolated that altered sites in Ssa1 affecting the cycle of substrate interaction. Together, our results point to a third, additional means by which J-proteins can drive Hsp70's ability to function in a wide range of cellular processes-modulating the Hsp70-substrate interaction cycle.

Language shifts in free indirect discourse

NARCIS (Netherlands)

Maier, Emar

Free indirect discourse is a way of reporting what a protagonist thinks or says that is distinct from both direct and indirect discourse. In particular, while pronouns and tenses are presented from the narrator's perspective, as in indirect discourse, other indexical and expressive elements reflect

Directe en indirecte werknemersparticipatie in Europa

NARCIS (Netherlands)

van Houten, Gijs; Akkerman, Agnes; Sluiter, Roderick; Jansen, Giedo; Vermeylen, Greet

2016-01-01

This study looks at different forms of direct and indirect employee participation in the EU. The research questions are: (1) which forms of direct and indirect employee participation can we distinguish?; (2) to what extent do forms of direct and indirect employee participation coincide within

Downregulation of β1,4-galactosyltransferase 1 inhibits CDK11p58-mediated apoptosis induced by cycloheximide

International Nuclear Information System (INIS)

Li Zejuan; Wang Hanzhou; Zong Hongliang; Sun Qing; Kong Xiangfei; Jiang Jianhai; Gu Jianxin

2005-01-01

Cyclin-dependent kinase 11 (CDK11; also named PITSLRE) is part of the large family of p34 cdc2 -related kinases whose functions appear to be linked with cell cycle progression, tumorigenesis, and apoptotic signaling. The mechanism that CDK11 p58 induces apoptosis is not clear. Some evidences suggested β1,4-galactosyltransferase 1 (β1,4-GT 1) might participate in apoptosis induced by CDK11 p58 . In this study, we demonstrated that ectopically expressed β1,4-GT 1 increased CDK11 p58 -mediated apoptosis induced by cycloheximide (CHX). In contrast, RNAi-mediated knockdown of β1,4-GT 1 effectively inhibited apoptosis induced by CHX in CDK11 p58 -overexpressing cells. For example, the cell morphological and nuclear changes were reduced; the loss of cell viability was prevented and the number of cells in sub-G1 phase was decreased. Knock down of β1,4-GT 1 also inhibited the release of cytochrome c from mitochondria and caspase-3 processing. Therefore, the cleavage of CDK11 p58 by caspase-3 was reduced. We proposed that β1,4-GT 1 might contribute to the pro-apoptotic effect of CDK11 p58 . This may represent a new mechanism of β1,4-GT 1 in CHX-induced apoptosis of CDK11 p58 -overexpressing cells

Direct and indirect effects of copper-contaminated sediments on the functions of model freshwater ecosystems.

Science.gov (United States)

Gardham, Stephanie; Chariton, Anthony A; Hose, Grant C

2015-01-01

Copper is acutely toxic to, and directly affects, primary producers and decomposers, which are key players in essential processes such as the nutrient cycle in freshwater ecosystems. Even though the indirect effects of metals (for example effects due to changes in species interactions) may be more common than direct effects, little is known about the indirect effects of copper on primary producers and decomposers. The effects of copper on phytoplankton, macrophytes, periphyton and organic matter decomposition in an outdoor lentic mesocosm facility were assessed, and links between the responses examined. Copper directly decreased macrophyte growth, subsurface organic matter decomposition, and the potential for high phytoplankton Chlorophyll a concentrations. However, periphyton cover and organic matter decomposition on the surface of the sediment were stimulated by the presence of copper. These latter responses were attributed to indirect effects, due to a reduction in grazing pressure from snails, particularly Physa acuta, in the higher copper-contaminated mesocosms. This permitted the growth of periphyton and other heterotrophs, ultimately increasing decomposition at the sediment surface. The present study demonstrates the pronounced influence indirect effects may have on ecological function, findings that may not be observed in traditional laboratory studies (which utilize single species or simplistic communities).

Proceedings of the American Power Conference. Volume 58-I

International Nuclear Information System (INIS)

McBride, A.E.

1996-01-01

This is volume 58-I of the proceedings of the American Power Conference, 1996, Technology for Competition and Globalization. The topics of the papers include power plant DC issues; cost of environmental compliance; advanced coal systems -- environmental performance; technology for competition in dispersed generation; superconductivity technologies for electric utility applications; power generation trends and challenges in China; aging in nuclear power plants; innovative and competitive repowering options; structural examinations, modifications and repairs; electric load forecasting; distribution planning; EMF effects; fuzzy logic and neural networks for power plant applications; electrokinetic decontamination of soils; integrated gasification combined cycle; advances in fusion; cooling towers; relays; plant controls; flue gas desulfurization; waste product utilization; and improved technologies

Neutron enrichment at midrapidity in {sup 58}Ni + {sup 58}Ni at 52 MeV/u

Energy Technology Data Exchange (ETDEWEB)

Theriault, D; Vallee, A; Gingras, L; Larochelle, Y; Roy, R; April, A; Beaulieu, L; Grenier, F; Lemieux, F; Moisan, J; Samri, M; Saint-Pierre, C; Turbide, S [Laval Univ., Lab. de Physique Nucleaire, Dept. de Physique, Quebec City, PQ (Canada); Yennello, S J; Martin, E; Winchester, E [Texas A and M Univ., College Station, TX (United States). Cyclotron Inst.

2003-07-01

By combining data from a charged particle {sup 58}Ni + {sup 58}Ni experiment at 52 MeV/u with an {sup 36}Ar + {sup 58}Ni experiment at 50 MeV/u for which free neutrons have been detected, an increase in the neutron to proton ratio of the whole nuclear material at midrapidity has been experimentally observed in the reaction {sup 58}Ni + {sup 58}Ni at 52 MeV/u. The neutron to proton ratio is measured above the initial neutron to proton ratio of the system. Neutron to proton ratio of the quasi-projectile emission is analysed for the same reactions and is seen to decrease below the ratio of the initial system. (authors)

The logic of indirect speech

Science.gov (United States)

Pinker, Steven; Nowak, Martin A.; Lee, James J.

2008-01-01

When people speak, they often insinuate their intent indirectly rather than stating it as a bald proposition. Examples include sexual come-ons, veiled threats, polite requests, and concealed bribes. We propose a three-part theory of indirect speech, based on the idea that human communication involves a mixture of cooperation and conflict. First, indirect requests allow for plausible deniability, in which a cooperative listener can accept the request, but an uncooperative one cannot react adversarially to it. This intuition is supported by a game-theoretic model that predicts the costs and benefits to a speaker of direct and indirect requests. Second, language has two functions: to convey information and to negotiate the type of relationship holding between speaker and hearer (in particular, dominance, communality, or reciprocity). The emotional costs of a mismatch in the assumed relationship type can create a need for plausible deniability and, thereby, select for indirectness even when there are no tangible costs. Third, people perceive language as a digital medium, which allows a sentence to generate common knowledge, to propagate a message with high fidelity, and to serve as a reference point in coordination games. This feature makes an indirect request qualitatively different from a direct one even when the speaker and listener can infer each other's intentions with high confidence. PMID:18199841

The hard X-ray spectrum of MAXI J1820+070 observed by Swift/BAT

Science.gov (United States)

Del Santo, Melania; Segreto, Alberto

2018-03-01

We have analysed the Swift/BAT data of the new transient MAXI J1820+070 (Atel #11399,#11400, #11403, #11404, #11406, #11418, #11420, #11421, #11423,#11424, #11425, #11425) collected from 2018-03-07 00:41:07 until 2018-03-15 06:20:58.

Indirect Cost Reimbursement: An Industrial View.

Science.gov (United States)

Bolton, Robert

1987-01-01

The meaning of indirect costs in an industrial environment is discussed. Other factors considered are corporate policies; nature of work being supported; the uniqueness of the work; who is doing the negotiating for industry; and indirect rates. Suggestions are offered for approaches to indirect cost reimbursement. (Author/MLW)

Assessing Natural Direct and Indirect Effects Through Multiple Pathways

DEFF Research Database (Denmark)

Lange, T; Rasmussen, M; Thygesen, Lau Caspar

2014-01-01

. The approach is an extension of the natural effect models proposed by Lange et al. (Am J Epidemiol. 2012;176(3):190-195). By allowing the analysis of distinct multiple pathways, the suggested approach adds to the capabilities of modern mediation techniques. Furthermore, the approach can be implemented using......Within the fields of epidemiology, interventions research and social sciences researchers are often faced with the challenge of decomposing the effect of an exposure into different causal pathways working through defined mediator variables. The goal of such analyses is often to understand...... the mechanisms of the system or to suggest possible interventions. The case of a single mediator, thus implying only 2 causal pathways (direct and indirect) from exposure to outcome, has been extensively studied. By using the framework of counterfactual variables, researchers have established theoretical...

Indirect Calorimetry in Mechanically Ventilated Patients

DEFF Research Database (Denmark)

Allingstrup, Matilde Jo; Kondrup, Jens; Perner, Anders

2017-01-01

Background and Aims: The 2 currently available indirect calorimeters, CCM Express Indirect Calorimeter (MedGraphics, St Paul, MN) and Quark RMR ICU Indirect Calorimeter (COSMED, Rome, Italy), have not been validated against a gold standard in mechanically ventilated patients. Our aim was to do so...... using a gold-standard, modified Tissot bell-spirometer method in mechanically ventilated patients who were hemodynamically, respiratory, and metabolically stable. Methods: We studied 30 patients undergoing general anesthesia and major gynecological surgery. We measured oxygen consumption ((Formula...... of 77 (167) with limits of agreement −249 to 404 kcal/d. Conclusions: The QUARK RMR ICU Indirect Calorimeter compared better with the gold standard for values of (Formula presented.) O2 and REE than did the CCM Express Indirect Calorimeter in mechanically ventilated patients who were circulatory...

Nitrate leaching, direct and indirect nitrous oxide fluxes from sloping cropland in the purple soil area, southwestern China

International Nuclear Information System (INIS)

Zhou Minghua; Zhu Bo; Butterbach-Bahl, Klaus; Wang Tao; Bergmann, Jessica; Brüggemann, Nicolas; Wang Zhenhua; Li Taikui; Kuang Fuhong

2012-01-01

This study provides a combined dataset on N loss pathways and fluxes from sloping cropland in the purple soil area, southwestern China. A lysimeter experiment was conducted to quantify nitrate leaching (May 2004–May 2010) and N 2 O emission (May 2009–May 2010) losses. Nitrate leaching was the dominant N loss pathway and annual leaching fluxes ranged from 19.2 to 53.4 kg N ha −1 , with significant differences between individual observation years (P 2 O emissions due to N fertilizer use were 1.72 ± 0.34 kg N ha −1 yr −1 , which corresponds to an emission factor of 0.58 ± 0.12%. However, indirect N 2 O emissions caused by nitrate leaching and surface runoff N losses, may contribute another 0.15–0.42 kg N ha −1 yr −1 . Our study shows that nitrate leaching lowered direct N 2 O emissions, highlighting the importance for a better understanding of the tradeoff between direct and indirect N 2 O emissions for the development of meaningful N 2 O emission strategies. - Highlights: ► High NO 3 − leaching losses lowered direct N 2 O emissions. ► Hydrological N losses induced un-neglected indirect N 2 O emissions. ► Considering both direct and indirect N 2 O emission is needed for reduction strategies. - High nitrate leaching losses from sloping croplands of purple soil are accompanied with reductions in direct N 2 O emissions and stimulations of indirect N 2 O emissions.

The Complexity of Indirect Translation

DEFF Research Database (Denmark)

Wenjie, L. I.

2017-01-01

its complex nature, and thus determined that many facets of ITr remain to be studied. The present article will try to encompass the complexity of ITr by looking into the reasons for translating indirectly, the challenge of finding out mediating texts (MTs), indirectness in both translation...... of which have been translated and interpreted indirectly through major languages like English, will be employed as examples. Hopefully, this study will offer more insights into the nature of translation as a social activity and raise further interests in studying translation as a complex phenomenon....

A simplified indirect bonding technique

Directory of Open Access Journals (Sweden)

Radha Katiyar

2014-01-01

Full Text Available With the advent of lingual orthodontics, indirect bonding technique has become an integral part of practice. It involves placement of brackets initially on the models and then their transfer to teeth with the help of transfer trays. Problems encountered with current indirect bonding techniques used are (1 the possibility of adhesive flash remaining around the base of the brackets which requires removal (2 longer time required for the adhesive to gain enough bond strength for secure tray removal. The new simplified indirect bonding technique presented here overcomes both these problems.

Fusion of 48Ti+58Fe and 58Ni+54Fe below the Coulomb barrier

Science.gov (United States)

Stefanini, A. M.; Montagnoli, G.; Corradi, L.; Courtin, S.; Bourgin, D.; Fioretto, E.; Goasduff, A.; Grebosz, J.; Haas, F.; Mazzocco, M.; Mijatović, T.; Montanari, D.; Pagliaroli, M.; Parascandolo, C.; Scarlassara, F.; Strano, E.; Szilner, S.; Toniolo, N.; Torresi, D.

2015-12-01

Background: No data on the fusion excitation function of 48Ti+58Fe in the energy region near the Coulomb barrier existed prior to the present work, while fusion of 58Ni+54Fe was investigated in detail some years ago, down to very low energies, and clear evidence of fusion hindrance was noticed at relatively high cross sections. 48Ti and 58Fe are soft and have a low-lying quadrupole excitation lying at ≈800 -900 keV only. Instead, 58Ni and 54Fe have a closed shell (protons and neutrons, respectively) and are rather rigid. Purpose: We aim to investigate (1) the possible influence of the different structures of the involved nuclei on the fusion excitation functions far below the barrier and, in particular, (2) whether hindrance is observed in 48Ti+58Fe , and to compare the results with current coupled-channels models. Methods: 48Ti beams from the XTU Tandem accelerator of INFN-Laboratori Nazionali di Legnaro were used. The experimental setup was based on an electrostatic beam separator, and fusion-evaporation residues (ERs) were detected at very forward angles. Angular distributions of ERs were measured. Results: Fusion cross sections of 48Ti+58Fe have been obtained in a range of nearly six orders of magnitude around the Coulomb barrier, down to σ ≃2 μ b . The sub-barrier cross sections of 48Ti+58Fe are much larger than those of 58Ni+54Fe . Significant differences are also observed in the logarithmic derivatives and astrophysical S factors. No evidence of hindrance is observed, because coupled-channels calculations using a standard Woods-Saxon potential are able to reproduce the data in the whole measured energy range. Analogous calculations for 58Ni+54Fe predict clearly too large cross sections at low energies. The two fusion barrier distributions are wide and display a complex structure that is only qualitatively fit by calculations. Conclusions: It is pointed out that all these different trends originate from the dissimilar low-energy nuclear structures of

Parametric-based thermodynamic analysis of organic Rankine cycle as bottoming cycle for combined-cycle power plant

International Nuclear Information System (INIS)

Qureshi, S.; Memon, A.G.; Abbasi, A.F.

2017-01-01

In Pakistan, the thermal efficiency of the power plants is low because of a huge share of fuel energy is dumped into the atmosphere as waste heat. The ORC (Organic Rankine Cycle) has been revealed as one of the promising technologies to recover waste heat to enhance the thermal efficiency of the power plant. In current work, ORC is proposed as a second bottoming cycle for existing CCPP (Combined Cycle Power Plant). In order to assess the efficiency of the plant, a thermodynamic model is developed in the ESS (Engineering Equation Solver) software. The developed model is used for parametric analysis to assess the effects of various operating parameters on the system performance. The analysis of results shows that the integration of ORC system with existing CCPP system enhances the overall power output in the range of 150.5-154.58 MW with 0.24-5% enhancement in the efficiency depending on the operating conditions. During the parametric analysis of ORC, it is observed that inlet pressure of the turbine shows a significant effect on the performance of the system as compared to other operating parameters. (author)

Accounting for the biogeochemical cycle of nitrogen in input-output life cycle assessment.

Science.gov (United States)

Singh, Shweta; Bakshi, Bhavik R

2013-08-20

Nitrogen is indispensable for sustaining human activities through its role in the production of food, animal feed, and synthetic chemicals. This has encouraged significant anthropogenic mobilization of reactive nitrogen and its emissions into the environment resulting in severe disruption of the nitrogen cycle. This paper incorporates the biogeochemical cycle of nitrogen into the 2002 input-output model of the U.S. economy. Due to the complexity of this cycle, this work proposes a unique classification of nitrogen flows to facilitate understanding of the interaction between economic activities and various flows in the nitrogen cycle. The classification scheme distinguishes between the mobilization of inert nitrogen into its reactive form, use of nitrogen in various products, and nitrogen losses to the environment. The resulting inventory and model of the US economy can help quantify the direct and indirect impacts or dependence of economic sectors on the nitrogen cycle. This paper emphasizes the need for methods to manage the N cycle that focus not just on N losses, which has been the norm until now, but also include other N flows for a more comprehensive view and balanced decisions. Insight into the N profile of various sectors of the 2002 U.S. economy is presented, and the inventory can also be used for LCA or Hybrid LCA of various products. The resulting model is incorporated in the approach of Ecologically-Based LCA and available online.

7 CFR 58.348 - Plastic cream.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Plastic cream. 58.348 Section 58.348 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products Bearing Usda Official Identification § 58.348 Plastic cream. The flavor shall be sweet, pleasing...

7 CFR 58.326 - Plastic cream.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Plastic cream. 58.326 Section 58.326 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.326 Plastic cream. To produce plastic cream eligible for official certification, the quality...

Cycling Time Trial Performance 4 Hours After Glycogen-Lowering Exercise Is Similarly Enhanced by Recovery Nondairy Chocolate Beverages Versus Chocolate Milk.

Science.gov (United States)

Upshaw, Adam U; Wong, Tiffany S; Bandegan, Arash; Lemon, Peter W

2016-02-01

Postexercise chocolate milk ingestion has been shown to enhance both glycogen resynthesis and subsequent exercise performance. To assess whether nondairy chocolate beverage ingestion post-glycogen-lowering exercise can enhance 20-km cycling time trial performance 4 hr later, eight healthy trained male cyclists (21.8 ± 2.3y, VO2max = 61.2 ± 1.4 ml·kg-1·min-1; M ± SD) completed a series of intense cycling intervals designed to lower muscle glycogen (Jentjens & Jeukendrup, 2003) followed by 4 hr of recovery and a subsequent 20-km cycling time trial. During the first 2 hr of recovery, participants ingested chocolate dairy milk (DAIRYCHOC), chocolate soy beverage (SOYCHOC), chocolate hemp beverage (HEMPCHOC), low-fat dairy milk (MILK), or a low-energy artificially sweetened, flavored beverage (PLACEBO) at 30-min intervals in a double-blind, counterbalanced repeated-measures design. All drinks, except the PLACEBO (247 kJ) were isoenergetic (2,107 kJ), and all chocolate-flavored drinks provided 1-g CHO·kg body mass-1·h-1. Fluid intake across treatments was equalized (2,262 ± 148 ml) by ingesting appropriate quantities of water based on drink intake. The CHO:PRO ratio was 4:1, 1.5:1, 4:1, and 6:1 for DAIRYCHOC, MILK, SOYCHOC, and HEMPCHOC, respectively. One-way analysis of variance with repeated measures showed time trial performance (DAIRYCHOC = 34.58 ± 2.5 min, SOYCHOC = 34.83 ± 2.2 min, HEMPCHOC = 34.88 ± 1.1 min, MILK = 34.47 ± 1.7 min) was enhanced similarly vs PLACEBO (37.85 ± 2.1) for all treatments (p = .019) These data suggest that postexercise macronutrient and total energy intake are more important for same-day 20-km cycling time trial performance after glycogen-lowering exercise than protein type or protein-to-carbohydrate ratio.

Potential pyrolysis pathway assessment for microalgae-based aviation fuel based on energy conversion efficiency and life cycle

International Nuclear Information System (INIS)

Guo, Fang; Wang, Xin; Yang, Xiaoyi

2017-01-01

Highlights: • High lipid content in microalgae increases energy conversion efficiency. • Indirect pathway has the highest mass ratio, energy ratio and energy efficiency. • The Isochrysis indirect pathway produces most kerosene component precursor. • The Isochrysis indirect pyrolysis pathway shows the best performance in LCA. - Abstract: Although the research of microalgae pyrolysis has been conducted for many years, there is a lack of investigations on energy efficiency and life cycle assessment. In this study, we investigated the biocrude yield and energy efficiency of direct pyrolysis, microalgae residue pyrolysis after lipid extraction (indirect pyrolysis), and different microalgae co-pyrolysis. This research also investigated the life cycle assessment of the three different pyrolysis pathways. A system boundary of Well-to-Wake (WTWa) was defined and included sub-process models, such as feedstock production, fuel production and pump-to-wheels (PTW) stages. The pathway of Isochrysis indirect pyrolysis shows the best performance in the mass ratio and energy ratio, produces the most kerosene component precursor, has the lowest WTWa total energy input, fossil fuel consumption and greenhouse gas emissions, and resultes in the best energy efficiency. All the evidence indicates that Isochrysis R2 pathway is a potential and optimal pyrolysis pathway to liquid biofuels. The mass ratio of pyrolysis biocrude is shown to be the decisive factor for different microalgae species. The sensitivity analysis results also indicates that the life cycle indicators are particularly sensitive to the mass ratio of pyrolysis biocrude for microalgae-based hydrotreated pyrolysis aviation fuel.

Part-Load Performance of a Wet Indirectly Fired Gas Turbine Integrated with an Organic Rankine Cycle Turbogenerator

DEFF Research Database (Denmark)

Pierobon, Leonardo; Nguyen, Tuong-Van; Mazzucco, Andrea

2014-01-01

Over the last years, much attention has been paid to the development of efficient and low-cost power systems for biomass-to-electricity conversion. This paper aims at investigating the design- and part-load performance of an innovative plant based on a wet indirectly fired gas turbine (WIFGT......-design performance is governed by the efficiency characteristics of the compressor and turbine serving the gas turbine unit....

7 CFR 58.431 - Hydrogen peroxide.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Hydrogen peroxide. 58.431 Section 58.431 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.431 Hydrogen peroxide. The solution shall comply with the specification of the U.S...

7 CFR 58.434 - Calcium chloride.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Calcium chloride. 58.434 Section 58.434 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.434 Calcium chloride. Calcium chloride, when used, shall meet the requirements of the Food...

7 CFR 58.331 - Starter distillate.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Starter distillate. 58.331 Section 58.331 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.331 Starter distillate. The refined flavor components when used to flavor butter and related...

Serum malondialdehyde levels during menstral cycle

African Journals Online (AJOL)

Administrator

hour overnight fasting during the three phases of their menstrual cycle. ... dysmenorrhea at some stage of their life usually between .... malaria. Afr. J. Biotechnol. 3(10): 560-563. Eser Killic, Suleyman Yazar, Recep Saraymen, Hatice Ozbilge ...

6 CFR 5.8 - Business information.

Science.gov (United States)

2010-01-01

... 6 Domestic Security 1 2010-01-01 2010-01-01 false Business information. 5.8 Section 5.8 Domestic... Freedom of Information Act § 5.8 Business information. (a) In general. Business information obtained by... this section. (b) Definitions. For purposes of this section: (1) Business information means commercial...

17 CFR 201.58 - Judicial review.

Science.gov (United States)

2010-04-01

... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Judicial review. 201.58 Section 201.58 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION RULES OF PRACTICE Regulations Pertaining to the Equal Access to Justice Act § 201.58 Judicial review. Judicial review of final...

7 CFR 58.136 - Rejected milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Rejected milk. 58.136 Section 58.136 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Milk § 58.136 Rejected milk. A plant shall reject specific milk from a producer if the milk fails to...

7 CFR 58.233 - Skim milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Skim milk. 58.233 Section 58.233 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Materials § 58.233 Skim milk. The skim milk shall be separated from whole milk meeting the requirements as...

40 CFR 205.58-2 - Tampering.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Tampering. 205.58-2 Section 205.58-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.58-2 Tampering. (a) For each configuration...

40 CFR 205.58-1 - Warranty.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Warranty. 205.58-1 Section 205.58-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.58-1 Warranty. (a) The vehicle manufacturer...

7 CFR 58.644 - Test methods.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Test methods. 58.644 Section 58.644 Agriculture... Procedures § 58.644 Test methods. (a) Microbiological. Microbiological determinations shall be made in accordance with the methods described in the latest edition of Standard Methods for the Examination of Dairy...

Indirect Reciprocity; A Field Experiment.

Science.gov (United States)

van Apeldoorn, Jacobien; Schram, Arthur

2016-01-01

Indirect reciprocity involves cooperative acts towards strangers, either in response to their kindness to third parties (downstream) or after receiving kindness from others oneself (upstream). It is considered to be important for the evolution of cooperative behavior amongst humans. Though it has been widely studied theoretically, the empirical evidence of indirect reciprocity has thus far been limited and based solely on behavior in laboratory experiments. We provide evidence from an online environment where members can repeatedly ask and offer services to each other, free of charge. For the purpose of this study we created several new member profiles, which differ only in terms of their serving history. We then sent out a large number of service requests to different members from all over the world. We observe that a service request is more likely to be rewarded for those with a profile history of offering the service (to third parties) in the past. This provides clear evidence of (downstream) indirect reciprocity. We find no support for upstream indirect reciprocity (in this case, rewarding the service request after having previously received the service from third parties), however. Our evidence of downstream indirect reciprocity cannot be attributed to reputational effects concerning one's trustworthiness as a service user.

46 CFR 58.20-5 - Design.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Design. 58.20-5 Section 58.20-5 Shipping COAST GUARD... SYSTEMS Refrigeration Machinery § 58.20-5 Design. (a) Refrigeration machinery may be accepted for installation provided the design, material, and fabrication comply with the applicable requirements of the ABS...

21 CFR 58.61 - Equipment design.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Equipment design. 58.61 Section 58.61 Food and... PRACTICE FOR NONCLINICAL LABORATORY STUDIES Equipment § 58.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall be...

7 CFR 58.813 - Dry whey.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Dry whey. 58.813 Section 58.813 Agriculture... Products Bearing Usda Official Identification § 58.813 Dry whey. The quality requirements for dry whey shall be in accordance with the U.S. Standards for Dry Whey. Supplemental Specifications for Plants...

7 CFR 58.443 - Whey handling.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Whey handling. 58.443 Section 58.443 Agriculture... Procedures § 58.443 Whey handling. (a) Adequate sanitary facilities shall be provided for the handling of whey. If outside, necessary precautions shall be taken to minimize flies, insects and development of...

7 CFR 58.243 - Checking quality.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Checking quality. 58.243 Section 58.243 Agriculture... Procedures § 58.243 Checking quality. All milk, milk products and dry milk products shall be subject to inspection and analysis by the dairy plant for quality and condition throughout each processing operation...

Yearly variation and annual cycle of total column ozone over New ...

Indian Academy of Sciences (India)

wave-like propagation of disturbances of rotational temperature of OH(8, 3). .... such as gravity waves, planetary waves, tides and ..... But, in case of Halley Bay, the most identical sea- ...... spheric water vapour; J. Geophys. Res. ... Greet P A, French W J R, Burns G B, Williams P F B, Lowe ... cycle; Indian J. Radio Space Phys.

Pedal indirect lymphangiography

International Nuclear Information System (INIS)

Lee, Kil Woo; Hong, Myung Sun; Kim, In Jae

1994-01-01

Recently, indirect lymphangiography has been developed as a relatively good and noninvasive imaging modality of the lymphatic system at extremities. But the disadvantage of the indirect lymphangiography is a low contrast ratio between the surrounding tissues and the contrast media in lymphatic vessels, because dimeric nonionic contrast media is water soluble and diluted in the proximal leg lymphatic vessels. We could have relatively better image than previously published images for the leg lymphatic system, when we injected contrast media with adequate high pressure in intradermal space of the interdigital areas at the foot dorsum. So, we would like to report the results. We could study all 9 lymphedemas(primary: 6, secondary: 3) from April 1990 to May 1993 on outpatient base. They were diagnosed as lymphedema clinically and radiologically. Ten ml of dimeric nonionic aget, iotrolan(Isovist 300) was injected into intradermal space with five 30-gauge needles. The injection speed was more than 0.2 ml/min. We have done one side pedal lymphangiogram in 30 minutes. The evaluation of the anterior superficial lymphatics was according to the criteria of the Weissleder. The results were as follows: 1. All lymphatic vessels from foot to inguinal area could be visualized. 2. Two or three inferior inguinal lymph nodes could be visualized about 42%. 3. The most common abnormal finding of the lymphedma was the neovascularization of the lymphatics on indirect pedal lymphangiogram. If we use adequate technique relatively high pressure injection, correct intradermal needle insertion, adequate soft tissue exposure technique indirect lymphangiography is considered to be a safe and noninvasive imaging modality for the evaluation of the lymphedema of lower extremity lymphatics including inferior inguinal lymph nodes

46 CFR 58.16-5 - Definition.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Definition. 58.16-5 Section 58.16-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Liquefied Petroleum Gases for Cooking and Heating § 58.16-5 Definition. For the purpose of this...

7 CFR 58.729 - Forming containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Forming containers. 58.729 Section 58.729 Agriculture... Procedures § 58.729 Forming containers. Containers either lined or unlined shall be assembled and stored in a sanitary manner to prevent contamination. The handling of containers by filler crews should be done with...

28 CFR 345.58 - Holiday pay.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Holiday pay. 345.58 Section 345.58... (FPI) INMATE WORK PROGRAMS Inmate Pay and Benefits § 345.58 Holiday pay. An inmate worker in FPI work status shall receive pay at the standard hourly rate, plus longevity where applicable, for all Federal...

40 CFR 58.60 - Federal monitoring.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Federal monitoring. 58.60 Section 58.60... QUALITY SURVEILLANCE Federal Monitoring § 58.60 Federal monitoring. The Administrator may locate and operate an ambient air monitoring site if the State or local agency fails to locate, or schedule to be...

21 CFR 58.90 - Animal care.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Animal care. 58.90 Section 58.90 Food and Drugs... FOR NONCLINICAL LABORATORY STUDIES Testing Facilities Operation § 58.90 Animal care. (a) There shall be standard operating procedures for the housing, feeding, handling, and care of animals. (b) All...

40 CFR 58.50 - Index reporting.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Index reporting. 58.50 Section 58.50... QUALITY SURVEILLANCE Air Quality Index Reporting § 58.50 Index reporting. (a) The State or where... quality index that complies with the requirements of appendix G to this part. (b) Reporting is required...

FancJ regulates interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1

Directory of Open Access Journals (Sweden)

Jianqiu Zou

2013-08-01

DNA damage response (DDR and the centrosome cycle are two of the most critical processes for maintaining a stable genome in animals. Sporadic evidence suggests a connection between these two processes. Here, we report our findings that six Fanconi Anemia (FA proteins, including FancI and FancJ, localize to the centrosome. Intriguingly, we found that the localization of FancJ to the mother centrosome is stimulated by a DNA interstrand crosslinker, Mitomycin C (MMC. We further show that, in addition to its role in interstrand crosslinking (ICL repair, FancJ also regulates the normal centrosome cycle as well as ICL induced centrosome amplification by activating the polo-like kinase 1 (PLK1. We have uncovered a novel function of FancJ in centrosome biogenesis and established centrosome amplification as an integral part of the ICL response.

7 CFR 58.730 - Filling containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Filling containers. 58.730 Section 58.730 Agriculture... Procedures § 58.730 Filling containers. Hot fluid cheese from the cookers may be held in hotwells or hoppers... shall effectively measure the desired amount of product into the pouch or container in a sanitary manner...

7 CFR 58.923 - Filling containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Filling containers. 58.923 Section 58.923 Agriculture... Procedures § 58.923 Filling containers. (a) The filling of small containers with product shall be done in a sanitary manner. The containers shall not contaminate or detract from the quality of the product in any way...

7 CFR 985.58 - Exempt oil.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Exempt oil. 985.58 Section 985.58 Agriculture... HANDLING OF SPEARMINT OIL PRODUCED IN THE FAR WEST Order Regulating Handling Volume Limitations § 985.58 Exempt oil. Oil held by a producer or handler on the effective date of this subpart shall not be...

7 CFR 58.919 - Pre-heat, pasteurization.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Pre-heat, pasteurization. 58.919 Section 58.919... Procedures § 58.919 Pre-heat, pasteurization. When pasteurization is intended or required by either the vat... requirements outlined in § 58.128. Pre-heat temperatures prior to ultra pasteurization will be those that have...

7 CFR 58.137 - Excluded milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Excluded milk. 58.137 Section 58.137 Agriculture... Milk § 58.137 Excluded milk. A plant shall not accept milk from a producer if: (a) The milk has been in...) Three of the last five milk samples have exceeded the maximum bacterial estimate of 500,000 per ml...

76 FR 18754 - J-W Pipeline Company; Notice of Motion for Extension of Rate Case Filing Deadline

Science.gov (United States)

2011-04-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR09-6-003] J-W Pipeline...-W Pipeline Company (J-W) filed a request for an extension consistent with the Commission's revised... extend the cycle for such reviews from three to five years.\\1\\ Therefore, J-W requests that the date for...

Supersymmetric dark matter: Indirect detection

International Nuclear Information System (INIS)

Bergstroem, L.

2000-01-01

Dark matter detection experiments are improving to the point where they can detect or restrict the primary particle physics candidates for non baryonic dark matter. The methods for detection are usually categorized as direct, i.e., searching for signals caused by passage of dark matter particles in terrestrial detectors, or indirect. Indirect detection methods include searching for antimatter and gamma rays, in particular gamma ray lines, in cosmic rays and high-energy neutrinos from the centre of the Earth or Sun caused by accretion and annihilation of dark matter particles. A review is given of recent progress in indirect detection, both on the theoretical and experimental side

INDIRECT LABOR COSTS AND IMPLICATIONS FOR OVERHEAD ALLOCATION

OpenAIRE

Bea Chiang

2013-01-01

Cost accounting typically allocates indirect labor cost to cost object based on direct labor hours. The allocation process implicitly assumes that indirect labor costs vary proportionally with direct labor hours. The assumption of a linear relationship between indirect and direct labor is particularly suspicious at low production volume levels because there tends to be a fixed component in indirect labor. The linearity assumption is also challenged by recent increasing complexity of indirect ...

Has accession to the EU affected business cycles?

Directory of Open Access Journals (Sweden)

Panagiotis EVANGELOPOULOS

2013-02-01

Full Text Available This paper undertakes to explain the relationship between EU accession and the length of business cycles, focusing specifically on whether participation in a multinational organization has, or has not, altered the length of the cycle. Employing a sample of nine EU countries (Austria, Denmark, Finland, Greece, Ireland, Portugal, Spain, Sweden and the UK we focused initially on annual data for per capita growth in GDP over a period of 59 years (1950-2008. For each country the sample was divided into two parts, one covering the period preceding accession to the EU and one is covering the accession year and succeeding years. Then, eliminating the background noise with the use of a periodogram, we proceeded to examine their spectral density plots. The results indicated that in the first years following accession, the countries tended to experience shorter cycles than they had previously. In the second phase the cycles were of the same duration as previous cycles. Finally, after a period of some years, the length of the cycles increased, as suggested by the J-shaped curve. This J-shaped growth curve applies for the countries that have joined the EU, strongly suggesting a causal relationship between accession to the EU and these specific characterristics of the curve. We cross-checked with a set of four non-EU member countries (Iceland, Norway, Switzerland and Turkey and found no change in the length of the business cycle in these countries.

A Novel Design Method for Optimizing an Indirect Forced Circulation Solar Water Heating System Based on Life Cycle Cost Using a Genetic Algorithm

Directory of Open Access Journals (Sweden)

Myeong Jin Ko

2015-10-01

Full Text Available To maximize the energy performance and economic benefits of solar water heating (SWH systems, the installation and operation-related design variables as well as those related to capacity must be optimized. This paper presents a novel design method for simultaneously optimizing the various design variables of an indirect forced-circulation SWH system that is based on the life cycle cost and uses a genetic algorithm. The effectiveness of the proposed method is assessed by evaluating the long-term performance corresponding to four cases, which are optimized using different annual solar fractions and sets of the design variables. When the installation and operation-related design variables were taken into consideration, it resulted in an efficient and economic design and an extra cost reduction of 3.2%–6.1% over when only the capacity-related design variables were considered. In addition, the results of parametric studies show that the slope and mass flow rate of the collector have a significant impact on the energy and economic performances of SWH systems. In contrast, the mass flow rate in the secondary circuit and the differences in the temperatures of the upper and lower dead bands of the differential controller have a smaller impact.

Dynamic design of gas sorption J-T refrigerator

International Nuclear Information System (INIS)

Chan, C.K.

1986-01-01

A long-life Joule-Thomson refrigerator which is heat powered, involves no sealing, and has few mechanical parts and is desirable for longterm sensor cooling in space. In the gas-sorption J-T refrigerator, cooling is achieved by gas sorption (either adsorption or absorption) processes. Currently, a modular, single-stage refrigerator is being designed and built to be operated at 20 K. The design was analyzed using a dynamic model, which is described here. The model includes the kinetics of the compressors and the heat switches, the heat transfer of the pre-coolers and the heat exchangers, the on/off ratio of the check valves, and the impedance of the J-T valve. The cooling power, the cycle time, and the operating conditions were obtained in terms of the power input, the heat sink temperature, and the J-T impedance

Dynamic design of gas sorption J-T refrigerator

Science.gov (United States)

Chan, C. K.

1986-01-01

A long-life Joule-Thomson refrigerator which is heat powered, involves no sealing, and has few mechanical parts is desirable for long-term sensor cooling in space. In the gas-sorption J-T refrigerator, cooling is achieved by gas sorption (either adsorption or absorption) processes. Currently, a modular, single-stage refrigerator is being designed and built to be operated at 20 K. The design was analyzed using a dynamic model, which is described here. The model includes the kinetics of the compressors and the heat switches, the heat transfer of the pre-coolers and the heat exchangers, the on/off ratio of the check valves, and the impedance of the J-T valve. The cooling power, the cycle time, and the operating conditions were obtained in terms of the power input, the heat sink temperature, and the J-T impedance.

Solar cycle variations of magnetopause locations

Czech Academy of Sciences Publication Activity Database

Němeček, Z.; Šafránková, J.; Lopez, R. E.; Dušík, Š.; Nouzák, L.; Přech, J.; Šimůnek, Jiří; Shue, J.-H.

2016-01-01

Roč. 58, č. 2 (2016), s. 240-248 ISSN 0273-1177 R&D Projects: GA ČR(CZ) GA14-19376S Institutional support: RVO:68378289 Keywords : magnetopause location * F-10.7 flux * solar cycle * solar wind velocity Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.401, year: 2016 http://www.sciencedirect.com/science/article/pii/S0273117715007115

7 CFR 58.424 - Monorail.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Monorail. 58.424 Section 58.424 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....424 Monorail. The monorail shall be constructed so as to prevent foreign material from falling on the...

7 CFR 58.435 - Color.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Color. 58.435 Section 58.435 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....435 Color. Coloring when used, shall be Annatto or any cheese or butter color which meet the...

7 CFR 58.717 - Whey.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Whey. 58.717 Section 58.717 Agriculture Regulations of....717 Whey. Whey used in cheese products should meet the requirements equivalent to USDA Extra Grade except that the moisture requirement for dry whey may be waived. ...

Differences in the locomotor-activating effects of indirect serotonin agonists in habituated and non-habituated rats.

Science.gov (United States)

Halberstadt, Adam L; Buell, Mahálah R; Price, Diana L; Geyer, Mark A

2012-07-01

The indirect serotonin (5-HT) agonist 3,4-methylenedioxymethamphetamine (MDMA) produces a distinct behavioral profile in rats consisting of locomotor hyperactivity, thigmotaxis, and decreased exploration. The indirect 5-HT agonist α-ethyltryptamine (AET) produces a similar behavioral profile. Using the Behavioral Pattern Monitor (BPM), the present investigation examined whether the effects of MDMA and AET are dependent on the novelty of the testing environment. These experiments were conducted in Sprague-Dawley rats housed on a reversed light cycle and tested during the dark phase of the light/dark cycle. We found that racemic MDMA (RS-MDMA; 3 mg/kg, SC) increased locomotor activity in rats tested in novel BPM chambers, but had no effect on locomotor activity in rats habituated to the BPM chambers immediately prior to testing. Likewise, AET (5 mg/kg, SC) increased locomotor activity in non-habituated animals but not in animals habituated to the test chambers. These results were unexpected because previous reports indicate that MDMA has robust locomotor-activating effects in habituated animals. To further examine the influence of habituation on MDMA-induced locomotor activity, we conducted parametric studies with S-(+)-MDMA (the more active enantiomer) in habituated and non-habituated rats housed on a standard or reversed light cycle. Light cycle was included as a variable due to reported differences in sensitivity to serotonergic ligands during the dark and light phases. In confirmation of our initial studies, rats tested during the dark phase and habituated to the BPM did not show an S-(+)-MDMA (3 mg/kg, SC)-induced increase in locomotor activity, whereas non-habituated rats did. By contrast, in rats tested during the light phase, S-(+)-MDMA increased locomotor activity in both non-habituated and habituated rats, although the response in habituated animals was attenuated. The finding that habituation and light cycle interact to influence MDMA- and AET

Analysis of indirect taxation in Ukraine

Directory of Open Access Journals (Sweden)

Khodyakova Olga V.

2014-01-01

Full Text Available The goal of the article is analysis of the structure and dynamics of indirect taxes for the previous five years and also the influence of indirect taxation upon formation of income of the State Budget of Ukraine. The article analyses the modern state of indirect taxation in Ukraine. Specific weight of the value added tax, excise tax and customs duty are considered in the structure of tax receipts of the consolidated budget of Ukraine as indirect taxes. The article shows that receipts of the State Budget of Ukraine are mostly provided by indirect taxes. The Ukrainian taxation system is mostly a factor of reduction of the level of economic growth and investment activity in the country and the existing system of administering is not completely capable of excluding the possibility of tax evasion. The prospect of further studies in this direction is improvement of organisation of tax control in Ukraine and differentiation of the value added tax rates depending on the level of consumption of goods and level of income of consumers.

Improvements in steam cycle electric power generating plants

International Nuclear Information System (INIS)

Bienvenu, Claude.

1973-01-01

The invention relates to a steam cycle electric energy generating plants of the type comprising a fossil or nuclear fuel boiler for generating steam and a turbo alternator group, the turbine of which is fed by the boiler steam. The improvement is characterized in that use is made of a second energy generating group in which a fluid (e.g. ammoniac) undergoes a condensation cycle the heat source of said cycle being obtained through a direct or indirect heat exchange with a portion of the boiler generated steam whereby it is possible without overloading the turbo-alternator group, to accomodate any increase of the boiler power resulting from the use of another fuel while maintaining a maximum energy output. This can be applied to electric power stations [fr

7 CFR 58.633 - Color.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Color. 58.633 Section 58.633 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....633 Color. Coloring used for ice cream and related products shall be those certified by the U.S. Food...

7 CFR 58.329 - Color.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Color. 58.329 Section 58.329 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....329 Color. Coloring, when used shall be Annatto or any color which is approved by the U.S. Food and...

7 CFR 58.632 - Acid.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Acid. 58.632 Section 58.632 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections....632 Acid. Acids used in sherbet shall be wholesome and of food grade quality and consist of one or...

7 CFR 58.721 - Salt.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Salt. 58.721 Section 58.721 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCT...

7 CFR 58.437 - Salt.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Salt. 58.437 Section 58.437 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCT...

7 CFR 58.328 - Salt.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Salt. 58.328 Section 58.328 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCT...

The life-cycle of the compost worm Eisenia ietida (Oligochaeta)

African Journals Online (AJOL)

161. The life-cycle of the compost worm Eisenia ietida (Oligochaeta). J.M. Venter* and A.J. Reinecke. Department of Zoology, Potchefstroom University for CHE, Potchefstroom, 2520 Republic of South Africa. Received 29 January, 1987; accepted 29 January 1988. To determine the full potential of the compost worm Eisenia ...

Structure of tetragonal martensite in the In95.42Cd4.58 cast alloy

Science.gov (United States)

Khlebnikova, Yu. V.; Egorova, L. Yu.; Rodionov, D. P.; Kazantsev, V. A.

2017-11-01

The structure of martensite in the In95.42Cd4.58 alloy has been studied by metallography, X-ray diffraction, dilatometry, and transmission electron microscopy. It has been shown that a massive structure built of colonies of tetragonal lamellar plates divided by a twin boundary {101}FCT is formed in the alloy under cooling below the martensite FCC → FCT transition temperature. The alloy recrystallizes after a cycle of FCT → FCC → FCT transitions with a decrease in the grain size by several times compared with the initial structure such fashion that the size of massifs and individual martensite lamella in the massif correlates with the change in the size of the alloy grain. Using thermal cycling, it has been revealed that the alloy tends to stabilize the high-temperature phase.

Comparative Life Cycle Assessment of Lignocellulosic Ethanol Production: Biochemical Versus Thermochemical Conversion

Science.gov (United States)

Mu, Dongyan; Seager, Thomas; Rao, P. Suresh; Zhao, Fu

2010-10-01

Lignocellulosic biomass can be converted into ethanol through either biochemical or thermochemical conversion processes. Biochemical conversion involves hydrolysis and fermentation while thermochemical conversion involves gasification and catalytic synthesis. Even though these routes produce comparable amounts of ethanol and have similar energy efficiency at the plant level, little is known about their relative environmental performance from a life cycle perspective. Especially, the indirect impacts, i.e. emissions and resource consumption associated with the production of various process inputs, are largely neglected in previous studies. This article compiles material and energy flow data from process simulation models to develop life cycle inventory and compares the fossil fuel consumption, greenhouse gas emissions, and water consumption of both biomass-to-ethanol production processes. The results are presented in terms of contributions from feedstock, direct, indirect, and co-product credits for four representative biomass feedstocks i.e., wood chips, corn stover, waste paper, and wheat straw. To explore the potentials of the two conversion pathways, different technological scenarios are modeled, including current, 2012 and 2020 technology targets, as well as different production/co-production configurations. The modeling results suggest that biochemical conversion has slightly better performance on greenhouse gas emission and fossil fuel consumption, but that thermochemical conversion has significantly less direct, indirect, and life cycle water consumption. Also, if the thermochemical plant operates as a biorefinery with mixed alcohol co-products separated for chemicals, it has the potential to achieve better performance than biochemical pathway across all environmental impact categories considered due to higher co-product credits associated with chemicals being displaced. The results from this work serve as a starting point for developing full life cycle

Social approach behaviors are similar on conventional versus reverse lighting cycles, and in replications across cohorts, in BTBR T+ tf/J, C57BL/6J, and vasopressin receptor 1B mutant mice

Directory of Open Access Journals (Sweden)

Mu Yang

2007-11-01

Full Text Available Mice are a nocturnal species, whose social behaviors occur primarily during the dark phase of the circadian cycle. However, laboratory rodents are frequently tested during their light phase, for practical reasons. We investigated the question of whether light phase testing presents a methodological pitfall for investigating mouse social approach behaviors. Three lines of mice were systematically compared. One cohort of each line was raised in a conventional lighting schedule and tested during the light phase, under white light illumination; another cohort was raised in a reverse lighting schedule and tested during their dark phase, under dim red light. Male C57BL/6J (B6 displayed high levels of sociability in our three-chambered automated social approach task when tested in either phase. BTBR T+ tf/J (BTBR displayed low levels of sociability in either phase. Five cohorts of vasopressin receptor subtype 1b (Avpr1b null mutants, heterozygotes, and wildtype littermate controls were tested in the same social approach paradigm: three in the dark phase and two in the light phase. All three genotypes displayed normal sociability in four out of the five replications. In the juvenile play test, testing phase had no effect on play soliciting behaviors in Avpr1b mice, but had modest effects on nose sniff and huddling. Taken together, these findings indicate that testing phase is not a crucial factor for studying some forms of social approach in juvenile and adult mice.

Indirect Reciprocity under Incomplete Observation

Science.gov (United States)

Nakamura, Mitsuhiro; Masuda, Naoki

2011-01-01

Indirect reciprocity, in which individuals help others with a good reputation but not those with a bad reputation, is a mechanism for cooperation in social dilemma situations when individuals do not repeatedly interact with the same partners. In a relatively large society where indirect reciprocity is relevant, individuals may not know each other's reputation even indirectly. Previous studies investigated the situations where individuals playing the game have to determine the action possibly without knowing others' reputations. Nevertheless, the possibility that observers of the game, who generate the reputation of the interacting players, assign reputations without complete information about them has been neglected. Because an individual acts as an interacting player and as an observer on different occasions if indirect reciprocity is endogenously sustained in a society, the incompleteness of information may affect either role. We examine the game of indirect reciprocity when the reputations of players are not necessarily known to observers and to interacting players. We find that the trustful discriminator, which cooperates with good and unknown players and defects against bad players, realizes cooperative societies under seven social norms. Among the seven social norms, three of the four suspicious norms under which cooperation (defection) to unknown players leads to a good (bad) reputation enable cooperation down to a relatively small observation probability. In contrast, the three trustful norms under which both cooperation and defection to unknown players lead to a good reputation are relatively efficient. PMID:21829335

Corporate governance cycles during transition

DEFF Research Database (Denmark)

Mygind, Niels; Demina, Natalia; Gregoric, Aleksandra

2004-01-01

-ing or exit stage. During transition the cycle reflects: privatization often with a high proportion of employee ownership like in Russia and in Slovenia; strong pressures for restructuring and owner-ship changes; limited possibility for external finance because of embryonic development of the fi......-nancial system. To provide simple hypothesis tests, we use Russian enterprise data for 1995-2003 and Slovenian data covering 1998-2003. In spite of differences in institutional development, con-cerning privatization and development of corporate governance institutions, we find that govern-ance cycles are broadly...... of ownership on managers, external domestic and foreign owners. JEL-codes: G3, J5, P2, P3 - Keywords: corporate governance, life-cycle, privatization, ownership change, transition economies, Russia and Slovenia....

Cycling biomechanics: a literature review.

Science.gov (United States)

Wozniak Timmer, C A

1991-01-01

Submitted in partial fulfillment for a Master of Science degree at the University of Pittsburgh, School of Health Related Professions, Pittsburgh, PA 1.5213 This review of current literature on cycling biomechanics emphasizes lower extremity muscle actions and joint excursions, seat height, pedal position, pedaling rate, force application, and pedaling symmetry. Guidelines are discussed for optimal seat height, pedal position, and pedaling rate. Force application in the power and recovery phases of cycling and the relationship of force application to pedaling symmetry are discussed. The need for a biomechanical approach to cycling exists since a great deal of the literature is primarily physiologic in nature. The purpose of this review is to make cyclists and their advisors aware of the biomechanics of cycling and guidelines to follow. This approach is also important because cycling is a very common form of exercise prescribed by physical therapists for clinic or home programs. Biomechanical aspects of cycling should be considered by cyclists at any level of participation and by physical therapists in order for goal-oriented, efficient cycling to occur. J Orthop Sports Phys Ther 1991;14(3):106-113.

Inventory charge calculations in the nuclear fuel cycle

International Nuclear Information System (INIS)

Salmon, R.

1975-09-01

Simplified methods are presented for the calculation of inventory charges or carrying charges on fuel, which represent the indirect component of the fuel cycle cost. These methods permit rapid calculation of the changes in fuel cycle cost caused by changes in the amount or timing of fuel cycle expenditures. The methods are developed by applying the discounted cash flow procedure to a single batch of fuel. In typical cases, this would be a batch representing equilibrium or steady-state reactor operation. The cost equations used are the same as those used in the computer code REFCO, described in ORNL-4695, which was based on the discounted cash flow procedure with continuous discounting. Equivalent procedures using the fixed charge rate concept also are developed. This is done in such a way that consistency with the discounted cash flow procedure is maintained. The fixed charge rate used here is defined in terms of tax rates and the interest rates on debt and equity capital. An effective inventory time is also defined. This is a function of the lead or lag time, the interest rates on capital, and the exposure time of the batch. Tabulated values of the effective inventory time and other useful functions, such as the ratio of indirect to direct cost, are included. Cost calculations using these tables agree with those produced by REFCO, the accuracy being within 0.001 mill/kWhr in the cases studied. (U.S.)

7 CFR 58.808 - Whey.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Whey. 58.808 Section 58.808 Agriculture Regulations of....808 Whey. Whey for processing shall be fresh and originate from the processing of products made from... by the Food and Drug Administration may be added to the whey for processing, except when restricted...

Prediction of direct and indirect genetic gains and genotypic correlations in rubber tree progenies

Directory of Open Access Journals (Sweden)

Cecília Khusala Verardi

2011-09-01

Full Text Available The objective of this work was to estimate the genetic parameters, genotypic and phenotypic correlations, and direct and indirect genetic gains among and within rubber tree (Hevea brasiliensis progenies. The experiment was set up at the Municipality of Jaú, SP, Brazil. A randomized complete block design was used, with 22 treatments (progenies, 6 replicates, and 10 plants per plot at a spacing of 3x3 m. Three‑year‑old progenies were assessed for girth, rubber yield, and bark thickness by direct and indirect gains and genotypic correlations. The number of latex vessel rings showed the best correlations, correlating positively and significantly with girth and bark thickness. Selection gains among progenies were greater than within progeny for all the variables analyzed. Total gains obtained were high, especially for girth increase and rubber yield, which were 93.38 and 105.95%, respectively. Young progeny selection can maximize the expected genetic gains, reducing the rubber tree selection cycle.

An Indirect Route for Ethanol Production

Energy Technology Data Exchange (ETDEWEB)

Eggeman, T.; Verser, D.; Weber, E.

2005-04-29

The ZeaChem indirect method is a radically new approach to producing fuel ethanol from renewable resources. Sugar and syngas processing platforms are combined in a novel way that allows all fractions of biomass feedstocks (e.g. carbohydrates, lignins, etc.) to contribute their energy directly into the ethanol product via fermentation and hydrogen based chemical process technologies. The goals of this project were: (1) Collect engineering data necessary for scale-up of the indirect route for ethanol production, and (2) Produce process and economic models to guide the development effort. Both goals were successfully accomplished. The projected economics of the Base Case developed in this work are comparable to today's corn based ethanol technology. Sensitivity analysis shows that significant improvements in economics for the indirect route would result if a biomass feedstock rather that starch hydrolyzate were used as the carbohydrate source. The energy ratio, defined as the ratio of green energy produced divided by the amount of fossil energy consumed, is projected to be 3.11 to 12.32 for the indirect route depending upon the details of implementation. Conventional technology has an energy ratio of 1.34, thus the indirect route will have a significant environmental advantage over today's technology. Energy savings of 7.48 trillion Btu/yr will result when 100 MMgal/yr (neat) of ethanol capacity via the indirect route is placed on-line by the year 2010.

The nuclear fuel cycle; Le cycle du combustible nucleaire

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-05-01

After a short introduction about nuclear power in the world, fission physics and the French nuclear power plants, this brochure describes in a digest way the different steps of the nuclear fuel cycle: uranium prospecting, mining activity, processing of uranium ores and production of uranium concentrates (yellow cake), uranium chemistry (conversion of the yellow cake into uranium hexafluoride), fabrication of nuclear fuels, use of fuels, reprocessing of spent fuels (uranium, plutonium and fission products), recycling of energetic materials, and storage of radioactive wastes. (J.S.)

Performance comparison of direct and indirect lighting systems

International Nuclear Information System (INIS)

Rubinstein, F.; Morse, O.; Clark, T.

1993-01-01

The performance of a retrofitted indirect lighting system was compared to the performance of a typical de-lamped direct lighting system in a partitioned office space. Power, illuminance and luminance measurements were made for the de-lamped direct lighting system and after installation of the indirect lighting system with various lamp and ballast combinations. Using the same lamps and ballasts, average workplace illuminance was slightly higher with indirect lighting than with direct lighting. With indirect lighting, workplace lumen efficacy was 4.5% lower due to the higher power draw of the lamps in the more open and cooler indirect fixtures. Indirect lighting with 36 watt T-8 lamps and electronic ballasts achieved an initial average workplace illuminance of 45 foot-candles in the partitioned office space at only 1.1 w/ft 2

High-intensity cycle interval training improves cycling and running performance in triathletes.

Science.gov (United States)

Etxebarria, Naroa; Anson, Judith M; Pyne, David B; Ferguson, Richard A

2014-01-01

Effective cycle training for triathlon is a challenge for coaches. We compared the effects of two variants of cycle high-intensity interval training (HIT) on triathlon-specific cycling and running. Fourteen moderately-trained male triathletes ([Formula: see text]O2peak 58.7 ± 8.1 mL kg(-1) min(-1); mean ± SD) completed on separate occasions a maximal incremental test ([Formula: see text]O2peak and maximal aerobic power), 16 × 20 s cycle sprints and a 1-h triathlon-specific cycle followed immediately by a 5 km run time trial. Participants were then pair-matched and assigned randomly to either a long high-intensity interval training (LONG) (6-8 × 5 min efforts) or short high-intensity interval training (SHORT) (9-11 × 10, 20 and 40 s efforts) HIT cycle training intervention. Six training sessions were completed over 3 weeks before participants repeated the baseline testing. Both groups had an ∼7% increase in [Formula: see text]O2peak (SHORT 7.3%, ±4.6%; mean, ±90% confidence limits; LONG 7.5%, ±1.7%). There was a moderate improvement in mean power for both the SHORT (10.3%, ±4.4%) and LONG (10.7%, ±6.8%) groups during the last eight 20-s sprints. There was a small to moderate decrease in heart rate, blood lactate and perceived exertion in both groups during the 1-h triathlon-specific cycling but only the LONG group had a substantial decrease in the subsequent 5-km run time (64, ±59 s). Moderately-trained triathletes should use both short and long high-intensity intervals to improve cycling physiology and performance. Longer 5-min intervals on the bike are more likely to benefit 5 km running performance.

7 CFR 58.132 - Basis for classification.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Basis for classification. 58.132 Section 58.132 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Milk § 58.132 Basis for classification. The quality classification of raw milk for manufacturing...

40 CFR 205.58 - In-use requirements.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 24 2010-07-01 2010-07-01 false In-use requirements. 205.58 Section 205.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.58 In-use requirements. ...

7 CFR 58.705 - Meaning of words.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.705 Section 58.705 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... § 58.705 Meaning of words. (a) Pasteurized process cheese and related products. Pasteurized process...

Hepatitis B Core Antigen in Hepatocytes of Chronic Hepatitis B: Comparison between Indirect Immunofluorescence and Immunoperoxidase Method

Science.gov (United States)

Tabassum, Shahina; Al-Mahtab, Mamun; Nessa, Afzalun; Jahan, Munira; Shamim Kabir, Chowdhury Mohammad; Kamal, Mohammad; Cesar Aguilar, Julio

2015-01-01

Background Hepatitis B virus (HBV) infection has many faces. Precore and core promoter mutants resemble inactive carrier status. The identification of hepatitis B core antigen (HBcAg) in hepatocytes may have variable clinical significance. The present study was undertaken to detect HBcAg in chronic hepatitis B (CHB) patients and to assess the efficacy of detection system by indirect immunofluorescence (IIF) and indirect immunoperoxidase (IIP). Materials and methods The study was done in 70 chronic HBV-infected patients. Out of 70 patients, eight (11.4%) were hepatitis B e antigen (HBeAg) positive and 62 (88.57%) were HBeAg negative. Hepatitis B core antigen was detected by indirect immunofluorescence (IIF) and indirect immunoperoxidase (IIP) methods in liver tissue. Results All HBeAg positive patients expressed HBcAg by both IIF and IIP methods. Out of 62 patients with HBeAg-negative CHB, HBcAg was detected by IIF in 55 (88.7%) patients and by IIP in 51 (82.26%) patients. A positive relation among viral load and HBcAg detection was also found. This was more evident in the case of HBeAg negative patients and showed a positive relation with HBV DNA levels. Conclusion Hepatitis B core antigen can be detected using the IIF from formalin fixed paraffin block preparation and also by IIP method. This seems to reflect the magnitudes of HBV replication in CHB. How to cite this article Raihan R, Tabassum S, Al-Mahtab M, Nessa A, Jahan M, Kabir CMS, Kamal M, Aguilar JC. Hepatitis B Core Antigen in Hepatocytes of Chronic Hepatitis B: Comparison between Indirect Immunofluorescence and Immunoperoxidase Method. Euroasian J Hepato-Gastroenterol 2015;5(1):7-10. PMID:29201677

DIRECT AND INDIRECT FLUORESCENT-ANTIBODY TECHNIQUES FOR THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM-TRACHOMA GROUP OF AGENTS1

Science.gov (United States)

Ross, Martin R.; Borman, Earle K.

1963-01-01

Ross, Martin R. (Connecticut State Department of Health, Hartford) and Earle K. Borman. Direct and indirect fluorescent-antibody techniques for the psittacosis-lymphogranuloma venereum-trachoma group of agents. J. Bacteriol. 85:851–858. 1963.—Direct and indirect fluorescent-antibody (FA) techniques were developed for the detection of group antigen in infected tissue cultures and the titration of group antibody in human antiserum. The growth of the agent of meningopneumonitis (MP) in mouse embryo lung cell monolayers was followed by infectivity and complement-fixing (CF) antigen titrations, and cytological examination of FA stained cultures. Although infectivity and CF antigen reached a peak at 2 days and remained constant for an additional 3 days, only cells tested 2 to 3 days after infection were suitable for FA staining with labeled anti-MP serum because of excessive artifacts in the older cultures. Fluorescein isothiocyanate-labeled rooster and guinea pig anti-MP serums and human antipsittacosis serums were titrated in direct FA and hemagglutination-inhibition (HI) tests. The rooster conjugate showed brighter staining and higher antibody titers than the guinea pig or human conjugates and was more effective in detecting minimal amounts of virus antigen. FA staining reactions with 1 and 2 units of labeled rooster serum were inhibited by unlabeled rooster serum but clear-cut inhibition with human antipsittacosis serum could not be demonstrated. The indirect FA technique was successfully used for the titration of group antibody in human serum. A comparison of the indirect FA, HI, and CF tests showed the indirect FA technique to be intermediate in sensitivity between the HI and CF tests. None of the three tests showed significant cross reactions with human serums reactive for influenza A and B; parainfluenza 1, 2, and 3; respiratory syncytial virus; Q fever; or the primary atypical pneumonia agent. PMID:14044954

7 CFR 58.728 - Cooking the batch.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Cooking the batch. 58.728 Section 58.728 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Procedures § 58.728 Cooking the batch. Each batch of cheese within the cooker, including the optional...

Coffee husk associated with firewood as fuel for indirect heating of drying air

Energy Technology Data Exchange (ETDEWEB)

Magalhaes, Edney Alves; Silva, Juarez de Sousa e; Silva, Jadir Nogueira da; Oliveira Filho, Delly [Universidade Federal de Vicosa (DEA/UFV), MG (Brazil). Dept. de Engenharia Agricola; Donzeles, Sergio Mauricio Lopes [Empresa de Pesquisa Agropecuaria de Minas Gerais (EPAMIG), Vicosa, MG (Brazil)

2008-07-01

The objective of this work was the performance analysis of a furnace, burning coffee husk associated with firewood to heat the drying air passing through a heat exchanger. For the analysis the temperature variation, the combustion quality, the heat losses and the furnace thermal efficiency were all monitored. Results showed that the furnace average efficiency was 58.3% and the heat losses in the exhaust were 24.3%. The presence of carbon monoxide in the exhaust gases (average 2982.8 ppm) had proven incomplete combustion, and suggesting that the combustion gases can not be used to directly drying of foods. Despite of indirect heating, the presented thermal efficiency indicates that the burning of coffee husks is one economic alternative for air heating in grain drying or in other agricultural processes. (author)

7 CFR 58.928 - Quality control tests.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be...

7 CFR 58.151 - Packaging and repackaging.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging and repackaging. 58.151 Section 58.151... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Packaging and General Identification § 58.151 Packaging and repackaging. (a) Packaging dairy products or cutting and repackaging all...

7 CFR 58.716 - Nonfat dry milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Nonfat dry milk. 58.716 Section 58.716 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Material § 58.716 Nonfat dry milk. Nonfat dry milk used in cheese products should meet the requirements...

7 CFR 58.905 - Meaning of words.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.905 Section 58.905 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Products § 58.905 Meaning of words. For the purpose of the regulations in this subpart, words in the...

7 CFR 58.726 - Cutting and grinding.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Cutting and grinding. 58.726 Section 58.726 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Procedures § 58.726 Cutting and grinding. The trimmed and cleaned cheese should be cut into sections of...

Ballistic fractures: indirect fracture to bone.

Science.gov (United States)

Dougherty, Paul J; Sherman, Don; Dau, Nathan; Bir, Cynthia

2011-11-01

Two mechanisms of injury, the temporary cavity and the sonic wave, have been proposed to produce indirect fractures as a projectile passes nearby in tissue. The purpose of this study is to evaluate the temporal relationship of pressure waves using strain gauge technology and high-speed video to elucidate whether the sonic wave, the temporary cavity, or both are responsible for the formation of indirect fractures. Twenty-eight fresh frozen cadaveric diaphyseal tibia (2) and femurs (26) were implanted into ordnance gelatin blocks. Shots were fired using 9- and 5.56-mm bullets traversing through the gelatin only, passing close to the edge of the bone, but not touching, to produce an indirect fracture. High-speed video of the impact event was collected at 20,000 frames/s. Acquisition of the strain data were synchronized with the video at 20,000 Hz. The exact time of fracture was determined by analyzing and comparing the strain gauge output and video. Twenty-eight shots were fired, 2 with 9-mm bullets and 26 with 5.56-mm bullets. Eight indirect fractures that occurred were of a simple (oblique or wedge) pattern. Comparison of the average distance of the projectile from the bone was 9.68 mm (range, 3-20 mm) for fractured specimens and 15.15 mm (range, 7-28 mm) for nonfractured specimens (Student's t test, p = 0.036). In this study, indirect fractures were produced after passage of the projectile. Thus, the temporary cavity, not the sonic wave, was responsible for the indirect fractures.

Indirect effects in dual radiation action

International Nuclear Information System (INIS)

Zaider, M.; Rossi, H.H.

1988-01-01

The basic aim in this paper is to establish the link between indirect effects of radiation action and the spatial distribution of radicals at the time of energy deposition as well as throughout subsequent diffusion and interaction. The fact that radicals diffuse for a finite distance before damaging a biomolecule has dramatic effects on their subsequent probability to result in lesions. Thus at very low DMSO concentrations, where p = 0.5, one expects - all other things being equal - some 75% of the lesions to result from indirect or semidirect lesions. The number calculated here is lower (15%), a direct result of the fact that such lesions involve proximity functions modulated by diffusion. At higher DMSO concentrations this percentage becomes progressively smaller, as expected. It appears thus that for low-LET radiation, the relative amount of indirect damage in single tracks (also termed intratrack or single events) action is very small. By contrast, intertrack (or two-event) contributions will have the ratio between direct and (indirect + semidirect) contributions given by p 2 /(1-p 2 ). The reason for this is that sublesions from different tracks are uniformly distributed throughout the cell nucleus; their probability of interaction should not depend on any previous diffusional processes. For the example given above (p = 0.5) they do expect 65% of intertrack (two-hit) lesions to have resulted from indirect or semidirect mechanisms. This contrast between the almost exclusively direct character of intratrack lesions and the dominant role of indirect action in intertrack lesions produced by low-LET radiation is an important conclusion of this study

Examining the direct and indirect effects of visual-verbal paired associate learning on Chinese word reading.

Science.gov (United States)

Georgiou, George; Liu, Cuina; Xu, Shiyang

2017-08-01

Associative learning, traditionally measured with paired associate learning (PAL) tasks, has been found to predict reading ability in several languages. However, it remains unclear whether it also predicts word reading in Chinese, which is known for its ambiguous print-sound correspondences, and whether its effects are direct or indirect through the effects of other reading-related skills such as phonological awareness and rapid naming. Thus, the purpose of this study was to examine the direct and indirect effects of visual-verbal PAL on word reading in an unselected sample of Chinese children followed from the second to the third kindergarten year. A sample of 141 second-year kindergarten children (71 girls and 70 boys; mean age=58.99months, SD=3.17) were followed for a year and were assessed at both times on measures of visual-verbal PAL, rapid naming, and phonological awareness. In the third kindergarten year, they were also assessed on word reading. The results of path analysis showed that visual-verbal PAL exerted a significant direct effect on word reading that was independent of the effects of phonological awareness and rapid naming. However, it also exerted significant indirect effects through phonological awareness. Taken together, these findings suggest that variations in cross-modal associative learning (as measured by visual-verbal PAL) place constraints on the development of word recognition skills irrespective of the characteristics of the orthography children are learning to read. Copyright © 2017 Elsevier Inc. All rights reserved.

Life cycle water consumption and wastewater generation impacts of a Marcellus shale gas well.

Science.gov (United States)

Jiang, Mohan; Hendrickson, Chris T; VanBriesen, Jeanne M

2014-01-01

This study estimates the life cycle water consumption and wastewater generation impacts of a Marcellus shale gas well from its construction to end of life. Direct water consumption at the well site was assessed by analysis of data from approximately 500 individual well completion reports collected in 2010 by the Pennsylvania Department of Conservation and Natural Resources. Indirect water consumption for supply chain production at each life cycle stage of the well was estimated using the economic input-output life cycle assessment (EIO-LCA) method. Life cycle direct and indirect water quality pollution impacts were assessed and compared using the tool for the reduction and assessment of chemical and other environmental impacts (TRACI). Wastewater treatment cost was proposed as an additional indicator for water quality pollution impacts from shale gas well wastewater. Four water management scenarios for Marcellus shale well wastewater were assessed: current conditions in Pennsylvania; complete discharge; direct reuse and desalination; and complete desalination. The results show that under the current conditions, an average Marcellus shale gas well consumes 20,000 m(3) (with a range from 6700 to 33,000 m(3)) of freshwater per well over its life cycle excluding final gas utilization, with 65% direct water consumption at the well site and 35% indirect water consumption across the supply chain production. If all flowback and produced water is released into the environment without treatment, direct wastewater from a Marcellus shale gas well is estimated to have 300-3000 kg N-eq eutrophication potential, 900-23,000 kg 2,4D-eq freshwater ecotoxicity potential, 0-370 kg benzene-eq carcinogenic potential, and 2800-71,000 MT toluene-eq noncarcinogenic potential. The potential toxicity of the chemicals in the wastewater from the well site exceeds those associated with supply chain production, except for carcinogenic effects. If all the Marcellus shale well wastewater is

A Simple Model of Global Aerosol Indirect Effects

Science.gov (United States)

Ghan, Steven J.; Smith, Steven J.; Wang, Minghuai; Zhang, Kai; Pringle, Kirsty; Carslaw, Kenneth; Pierce, Jeffrey; Bauer, Susanne; Adams, Peter

2013-01-01

Most estimates of the global mean indirect effect of anthropogenic aerosol on the Earth's energy balance are from simulations by global models of the aerosol lifecycle coupled with global models of clouds and the hydrologic cycle. Extremely simple models have been developed for integrated assessment models, but lack the flexibility to distinguish between primary and secondary sources of aerosol. Here a simple but more physically based model expresses the aerosol indirect effect (AIE) using analytic representations of cloud and aerosol distributions and processes. Although the simple model is able to produce estimates of AIEs that are comparable to those from some global aerosol models using the same global mean aerosol properties, the estimates by the simple model are sensitive to preindustrial cloud condensation nuclei concentration, preindustrial accumulation mode radius, width of the accumulation mode, size of primary particles, cloud thickness, primary and secondary anthropogenic emissions, the fraction of the secondary anthropogenic emissions that accumulates on the coarse mode, the fraction of the secondary mass that forms new particles, and the sensitivity of liquid water path to droplet number concentration. Estimates of present-day AIEs as low as 5 W/sq m and as high as 0.3 W/sq m are obtained for plausible sets of parameter values. Estimates are surprisingly linear in emissions. The estimates depend on parameter values in ways that are consistent with results from detailed global aerosol-climate simulation models, which adds to understanding of the dependence on AIE uncertainty on uncertainty in parameter values.

Expression of future prospective in indirect speech

Directory of Open Access Journals (Sweden)

Bodnaruk Elena Vladimirovna

2015-03-01

Full Text Available The article analyzes the characteristics and use of grammatical semantics and lexical and grammatical means used to create future prospects in double indirect discourse. The material for the study were epic works by contemporary German writers. In the analysis of the empirical material it has been pointed out that indirect discourse has preterial basis and is the kind of most frequent inner speech of characters. The most widely used form with future semantics in preterial indirect speech is conditional I, formally having a conjunctive basis, but is mostly used with the indicative semantics. Competitive to conditional I in indirect speech is preterial indicative. A characteristic feature of the indirect speech is the use of modal verbs, which, thanks to its semantics is usually referred as an action at a later term, creating the prospect of future statements. The most frequent were modal verbs wollen and sollen in the form of the preterite, more rare verbs were m ssen and k nnen. German indirect speech distinguishes the ability to use forms on the basis of conjunctive: preterite and plusquamperfect of conjunctive. Both forms express values similar to those of the indicative. However, conjunctive forms the basis of the data shown in a slightly more pronounced seme of uncertainty that accompanies future uses of these forms in indirect speech. In addition, plusquamperfect conjunctive differs from others by the presence of the seme of completeness.

Synchronization of indirectly coupled Lorenz oscillators

Indian Academy of Sciences (India)

Synchronization of indirectly coupled Lorenz oscillators: An experimental study. Amit Sharma Manish Dev Shrimali. Synchronization, Coupled Systems and Networks Volume 77 Issue 5 November 2011 pp 881-889 ... The in-phase and anti-phase synchronization of indirectly coupled chaotic oscillators reported in Phys. Rev ...

Indirect estimators in US federal programs

CERN Document Server

1996-01-01

In 1991, a subcommittee of the Federal Committee on Statistical Methodology met to document the use of indirect estimators - that is, estimators which use data drawn from a domain or time different from the domain or time for which an estimate is required. This volume comprises the eight reports which describe the use of indirect estimators and they are based on case studies from a variety of federal programs. As a result, many researchers will find this book provides a valuable survey of how indirect estimators are used in practice and which addresses some of the pitfalls of these methods.

21 CFR 58.35 - Quality assurance unit.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Quality assurance unit. 58.35 Section 58.35 Food... LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Organization and Personnel § 58.35 Quality assurance unit. (a) A testing facility shall have a quality assurance unit which shall be responsible for...

7 CFR 58.335 - Quality control tests.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow...

7 CFR 58.444 - Packaging and repackaging.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging and repackaging. 58.444 Section 58.444... Procedures § 58.444 Packaging and repackaging. (a) Packaging rindless cheese or cutting and repackaging all styles of bulk cheese shall be conducted under rigid sanitary conditions. The atmosphere of the packaging...

7 CFR 58.340 - Printing and packaging.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Printing and packaging. 58.340 Section 58.340... Procedures § 58.340 Printing and packaging. Printing and packaging of consumer size containers of butter... packaging equipment should be provided. The outside cartons should be removed from bulk butter in a room...

7 CFR 58.935 - Chocolate and cocoa.

Science.gov (United States)

2010-01-01

... Materials § 58.935 Chocolate and cocoa. Such products used as flavor ingredients shall meet the requirements of the Food and Drug Administration, “Definitions and Standards of Identity for Cocoa Products... 7 Agriculture 3 2010-01-01 2010-01-01 false Chocolate and cocoa. 58.935 Section 58.935 Agriculture...

7 CFR 58.53 - Supervisor of packaging required.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Supervisor of packaging required. 58.53 Section 58.53... Packaging Products with Official Identification § 58.53 Supervisor of packaging required. The official....54 through 58.57, shall be done only under the supervision of a supervisor of packaging. The...

Mobile Laser Indirect Ophthalmoscope: For the Induction of Choroidal Neovascularization in a Mouse Model.

Science.gov (United States)

Weinberger, Dov; Bor-Shavit, Elite; Barliya, Tilda; Dahbash, Mor; Kinrot, Opher; Gaton, Dan D; Nisgav, Yael; Livnat, Tami

2017-11-01

This study aims to evaluate and standardize the reliability of a mobile laser indirect ophthalmoscope in the induction of choroidal neovascularization (CNV) in a mouse model. A diode laser indirect ophthalmoscope was used to induce CNV in pigmented male C57BL/6J mice. Standardization of spot size and laser intensity was determined using different aspheric lenses with increasing laser intensities applied around the optic disc. Development of CNV was evaluated 1, 5, and 14 days post laser application using fluorescein angiography (FA), histology, and choroidal flat mounts stained for the endothelial marker CD31 and FITC-dextran. Correlation between the number of laser hits to the number and size of developed CNV lesions was determined using flat mount choroid staining. The ability of intravitreally injected anti-human and anti-mouse VEGF antibodies to inhibit CNV induced by the mobile laser was evaluated. Laser parameters were standardized on 350 mW for 100 msec, using the 90 diopter lens to accomplish the highest incidence of Bruch's membrane rupture. CNV lesions' formation was validated on days 5 and 14 post laser injury, though FA showed leakage on as early as day 1. The number of laser hits was significantly correlated with the CNV area. CNV growth was successfully inhibited by both anti-human and mouse VEGF antibodies. The mobile laser indirect ophthalmoscope can serve as a feasible and a reliable alternative method for the CNV induction in a mouse model.

THE INDIRECT OBJECT (IO) – ALBANIAN AND ENGLISH

OpenAIRE

Shkelqim Millaku; Xhevahire Topanica

2016-01-01

The aim of this study is too corporate the function of the indirect object between Albanian and English language. The function and the Albanian typical case for indirect object are dative and ablative. This grammatical phenomena is the full contrast between two languages because in English language doesn’t exist dative and ablative us in Albanian. In Albanian and English language, the indirect object is more heterogenic than the direct object. The indirect (direct) object in both of languages...

46 CFR 58.05-5 - Astern power.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Astern power. 58.05-5 Section 58.05-5 Shipping COAST... RELATED SYSTEMS Main Propulsion Machinery § 58.05-5 Astern power. (a) All vessels shall have sufficient power for going astern to secure proper control of the ship in all normal circumstances. ...

1 CFR 5.8 - Form of citation.

Science.gov (United States)

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Form of citation. 5.8 Section 5.8 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.8 Form of citation. Without prejudice to any other form of citation, Federal Register material may be cited by volume...

7 CFR 58.642 - Quality control tests.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.642 Section 58.642... Procedures § 58.642 Quality control tests. All mix ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow line samples as...

7 CFR 58.733 - Quality control tests.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.733 Section 58.733... Procedures § 58.733 Quality control tests. (a) Chemical analyses. The following chemical analyses shall be... pasteurization by means of the phosphatase test, as well as any other tests necessary to assure good quality...

7 CFR 58.248 - Nonfat dry milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Nonfat dry milk. 58.248 Section 58.248 Agriculture... Products Bearing Usda Official Identification § 58.248 Nonfat dry milk. (a) Nonfat dry milk in commercial....S. Standard Grade. (b) Regular nonfat dry milk in consumer size packages which bears an official...

46 CFR 58.10-10 - Diesel engine installations.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Diesel engine installations. 58.10-10 Section 58.10-10... MACHINERY AND RELATED SYSTEMS Internal Combustion Engine Installations § 58.10-10 Diesel engine installations. (a) The requirements of § 58.10-5 (a), (c), and (d) shall apply to diesel engine installations...

Preimplantation genetic diagnosis of X-linked diseases examined by indirect linkage analysis.

Science.gov (United States)

Borgulova, I; Putzova, M; Soldatova, I; Krautova, L; Pecnova, L; Mika, J; Kren, R; Potuznikova, P; Stejskal, D

2015-01-01

Many centers of assisted reproduction in the Czech Republic offer preimplantation genetic diagnosis with fluorescent in situ hybridization (FISH) to couples requiring preimplantation genetic diagnosis (PGD) of X-linked diseases. However, this process results in discarding all male embryos and is not able to distinguish a carrier or healthy female embryo in X-linked recessive disorders. The main aim of this study was to summarize a six-year period of PGD of X-linked monogenic diseases using indirect linkage analysis. We wanted to accentuate the advantage indirect analysis of PGD using multiple displacement amplification (MDA) followed by short tandem repeat (STR) analysis. We present forty-six PGD cycles, including pre-case haplotyping (PGH) panel, for fifteen X-linked diseases. Embryo transfer was made thirty-eight times and gravidity was confirmed in thirteen female probands with a success rate of pregnancy calculated at 42 %. PGD procedure using MDA amplification followed by STR analysis provides help in identifying genetic defects within embryos prior to implantation. The reliability of the method was also supported by high pregnancy rate compared to other publications, which commonly achieved a 30-35 % success rate (Tab. 2, Fig. 1, Ref. 33).

The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti

Science.gov (United States)

Pini, Francesco; Frage, Benjamin; Ferri, Lorenzo; De Nisco, Nicole J.; Mohapatra, Saswat S.; Taddei, Lucilla; Fioravanti, Antonella; Dewitte, Frederique; Galardini, Marco; Brilli, Matteo; Villeret, Vincent; Bazzicalupo, Marco; Mengoni, Alessio; Walker, Graham C.; Becker, Anke; Biondi, Emanuele G.

2013-01-01

SUMMARY Sinorhizobium meliloti is a soil bacterium that invades the root nodules it induces on Medicago sativa, whereupon it undergoes an alteration of its cell cycle and differentiates into nitrogen-fixing, elongated and polyploid bacteroid with higher membrane permeability. In Caulobacter crescentus, a related alphaproteobacterium, the principal cell cycle regulator, CtrA, is inhibited by the phosphorylated response regulator DivK. The phosphorylation of DivK depends on the histidine kinase DivJ, while PleC is the principal phosphatase for DivK. Despite the importance of the DivJ in C. crescentus, the mechanistic role of this kinase has never been elucidated in other Alphaproteobacteria. We show here that the histidine kinases DivJ together with CbrA and PleC participate in a complex phosphorylation system of the essential response regulator DivK in S. meliloti. In particular, DivJ and CbrA are involved in DivK phosphorylation and in turn CtrA inactivation, thereby controlling correct cell cycle progression and the integrity of the cell envelope. In contrast, the essential PleC presumably acts as a phosphatase of DivK. Interestingly, we found that a DivJ mutant is able to elicit nodules and enter plant cells, but fails to establish an effective symbiosis suggesting that proper envelope and/or low CtrA levels are required for symbiosis. PMID:23909720

Indirect reciprocity with optional interactions.

Science.gov (United States)

Ghang, Whan; Nowak, Martin A

2015-01-21

Indirect reciprocity is a mechanism for the evolution of cooperation that is relevant for prosocial behavior among humans. Indirect reciprocity means that my behavior towards you also depends on what you have done to others. Indirect reciprocity is associated with the evolution of social intelligence and human language. Most approaches to indirect reciprocity assume obligatory interactions, but here we explore optional interactions. In any one round a game between two players is offered. A cooperator accepts a game unless the reputation of the other player indicates a defector. For a game to take place, both players must accept. In a game between a cooperator and a defector, the reputation of the defector is revealed to all players with probability Q. After a sufficiently large number of rounds the identity of all defectors is known and cooperators are no longer exploited. The crucial condition for evolution of cooperation can be written as hQB>1, where h is the average number of rounds per person and B=(b/c)-1 specifies the benefit-to-cost ratio. We analyze both stochastic and deterministic evolutionary game dynamics. We study two extensions that deal with uncertainty: hesitation and malicious gossip. Copyright © 2014 Elsevier Ltd. All rights reserved.

Cycle 7 outage experience

International Nuclear Information System (INIS)

Gadeken, A.D.

1986-03-01

The scheduled 58-day refueling outage in preparation for the seventh operating cycle of the Fast Flux Test Facility (FFTF) was successfully completed three days ahead of schedule. The planning and execution of the outage was greatly aided by Project/2 automated scheduling capabilities. For example, the use of ''maintenance windows'' and resource loading capabilities was particularly effective. The value of the planning process was demonstrated by the smooth transition into the outage phase after an early shutdown and set the stage for our best outage to date

7 CFR 58.250 - Dry whole milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Dry whole milk. 58.250 Section 58.250 Agriculture... Products Bearing Usda Official Identification § 58.250 Dry whole milk. Dry whole milk in commercial bulk... Grades of Dry Whole Milk. Quality requirements for dry whole milk in consumer packages shall be for U.S...

7 CFR 58.505 - Meaning of words.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.505 Section 58.505 Agriculture... for Plants Manufacturing and Packaging Cottage Cheese § 58.505 Meaning of words. For the purpose of the regulations in this subpart, words in the singular form shall be deemed to impart the plural and...

Indirect Medical Education and Disproportionate Share Adj...

Data.gov (United States)

U.S. Department of Health & Human Services — Indirect Medical Education and Disproportionate Share Adjustments to Medicare Inpatient Payment Rates The indirect medical education (IME) and disproportionate share...

[Effects of biochar on soil nitrogen cycle and related mechanisms: a review].

Science.gov (United States)

Pan, Yi-Fan; Yang, Min; Dong, Da; Wu, Wei-Xiang

2013-09-01

Biochar has its unique physical and chemical properties, playing a significant role in soil amelioration, nutrient retention, fertility improvement, and carbon storage, and being a hotspot in the research areas of soil ecosystem, biogeochemical cycling, and agricultural carbon sequestration. As a kind of anthropogenic materials, biochar has the potential in controlling soil nitrogen (N) cycle directly or indirectly, and thus, has profound effects on soil ecological functions. This paper reviewed the latest literatures regarding the effects of biochar applications on soil N cycle, with the focuses on the nitrogen species adsorption and the biochemical processes (nitrification, denitrification, and nitrogen fixation) , and analyzed the related action mechanisms of biochar. The future research areas for better understanding the interactions between biochar and soil N cycle were proposed.

Indirect Comorbidity in Childhood and Adolescence

Directory of Open Access Journals (Sweden)

William eCopeland

2013-11-01

Full Text Available Objective: Comorbidity between psychiatric disorders is common, but pairwise associations between two disorders may be explained by the presence of other diagnoses that are associated with both disorders or indirect comorbidity. Method: Comorbidities of common childhood psychiatric disorders were tested in three community samples of children ages 6 to 17 (8931 observations of 2965 subjects. Psychiatric disorder status in all three samples was assessed with the Child and Adolescent Psychiatric Assessment. Indirect comorbidity was defined as A-B associations that decreased from significance to nonsignificance after adjusting for other disorders. Results: All tested childhood psychiatric disorders were positively associated in bivariate analyses. After adjusting for comorbidities, many ssociations involving a behavioral disorder and an emotional disorder were attenuated suggesting indirect comorbidity. Generalized anxiety and depressive disorders displayed a very high level of overlap (adjusted OR=37.9. All analyses were rerun with depressive disorders grouped with generalized anxiety disorder in a single distress disorders category. In these revised models, all associations between and emotional disorder and a behavior disorder met our criteria for indirect comorbidity except for the association of oppositional defiant disorder with distress disorders (OR=11.3. Follow-up analyses suggested that the indirect associations were primarily accounted for by oppositional defiant disorder and the distress disorder category. There was little evidence of either sex differences or differences by developmental period Conclusions: After accounting for the overlap between depressive disorders with generalized anxiety disorder, direct comorbidity between emotional and behavioral disorders was uncommon. When there was evidence of indirect comorbidity, ODD and distress disorders were the key intermediary diagnoses accounting for the apparent associations.

29 CFR 20.58 - Rate of interest.

Science.gov (United States)

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Rate of interest. 20.58 Section 20.58 Labor Office of the Secretary of Labor FEDERAL CLAIMS COLLECTION Interest, Penalties and Administrative Costs § 20.58 Rate of interest. (a) The rate of interest assessed shall be the rate of the current value of funds to the United...

7 CFR 58.405 - Meaning of words.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.405 Section 58.405 Agriculture... for Plants Manufacturing and Packaging Cheese § 58.405 Meaning of words. For the purpose of the regulations in this subpart, words in the singular form shall be deemed to impart the plural and vice versa as...

7 CFR 58.205 - Meaning of words.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.205 Section 58.205 Agriculture... Whole Milk, and Dry Buttermilk § 58.205 Meaning of words. For the purpose of the regulations in this subpart, words in the singular form shall be deemed to impart the plural and vice versa, as the case may...

Gas-phase organics in environmental tobacco smoke: 2. Exposure-relevant emission factors and indirect exposures from habitual smoking

Science.gov (United States)

Singer, Brett C.; Hodgson, Alfred T.; Nazaroff, William W.

Sorption of emitted gas-phase organic compounds onto material surfaces affects environmental tobacco smoke (ETS) composition and exposures indoors. We have introduced a new metric, the exposure relevant emission factor (EREF) that accounts for sorptive uptake and reemission to give the mass of individual ETS constituents available for exposure over a day in which smoking occurs. This paper describes month-long experiments to investigate sorption effects on EREFs and potential ETS exposures under habitual smoking conditions. Cigarettes were smoked in a 50-m 3 furnished room over a 3-h period 6-7 days per week, with continuous ventilation at 0.3, 0.6, or 2.1 h -1. Organic gas concentrations were measured every few days over 4-h "smoking", 10-h "post-smoking" and 10-h "background" periods. Concentration patterns of volatile ETS components including 1,3-butadiene, benzene and acrolein were similar to those calculated for a theoretical non-sorbing tracer, indicating limited sorption. Concentrations of ETS tracers, e.g. 3-ethenylpyridine (3-EP) and nicotine, and lower volatility toxic air contaminants including phenol, cresols, and naphthalene increased as experiments progressed, indicating mass accumulation on surfaces and higher desorption rates. Daily patterns stabilized after week 2, yielding a steady daily cycle of ETS concentrations associated with habitual smoking. EREFs for sorbing compounds were higher under steady cycle versus single-day smoking conditions by ˜50% for 3-EP, and by 2-3 times for nicotine, phenol, cresols, naphthalene, and methylnaphthalenes. Our results provide relevant information about potential indirect exposures from residual ETS (non-smoker enters room shortly after smoker finishes) and from reemission, and their importance relative to direct exposures (non-smoker present during smoking). Under the conditions examined, indirect exposures accounted for a larger fraction of total potential exposures for sorbing versus non-sorbing compounds

Land Use and Land-use Changes in Life Cycle Assessment

DEFF Research Database (Denmark)

De Rosa, Michele

2017-01-01

The assessment of Land Uses and Land-use Changes (LULUC) impacts has become increasingly complex. Sophisticated modelling tools such as Life Cycle Assessment (LCA) are employed to capture both direct and indirect damages. However, quantitative assessments are often incomplete, dominated...... by environmental aspects. Land uses are a multidisciplinary matter and environmental and sustainable development policies intertwine. Yet, LCAs mostly focus on environmental impacts excluding socioeconomic implications of land occupation. This paper investigates the limitations of current LULUC modelling practices....... Consequently, results informing land policies may be biased towards determined development strategies or hide indirect effects and socioeconomic damages caused by large-scale land acquisitions, such as violation of tenure rights, speculation and displacement. Quantitative assessments of LULUC impacts...

Occlusal force is correlated with cognitive function directly as well as indirectly via food intake in community-dwelling older Japanese: From the SONIC study.

Science.gov (United States)

Ikebe, Kazunori; Gondo, Yasuyuki; Kamide, Kei; Masui, Yukie; Ishizaki, Taturo; Arai, Yasumichi; Inagaki, Hiroki; Nakagawa, Takeshi; Kabayama, Mai; Ryuno, Hirochika; Okubo, Hitomi; Takeshita, Hajime; Inomata, Chisato; Kurushima, Yuko; Mihara, Yusuke; Hatta, Kohdai; Fukutake, Motoyoshi; Enoki, Kaori; Ogawa, Taiji; Matsuda, Ken-Ichi; Sugimoto, Ken; Oguro, Ryosuke; Takami, Yoichi; Itoh, Norihisa; Takeya, Yasushi; Yamamoto, Koichi; Rakugi, Hiromi; Murakami, Shinya; Kitamura, Masahiro; Maeda, Yoshinobu

2018-01-01

Growing evidence suggests that oral health may be an important factor associated with cognitive function in aged populations. However, many previous studies on this topic used insensitive oral indicators or did not include certain essential covariates. Thus, we examined the association between occlusal force and cognitive function in a large sample of older adults, controlling for dietary intake, vascular risk factors, inflammatory biomarkers, depression, and genetic factors. In this cross-sectional study of older community-dwelling Japanese adults, we examined data collected from 994 persons aged 70 years and 968 persons aged 80 years. Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment (MoCA-J). Oral status and function were evaluated according to the number of remaining teeth, periodontal pocket depth, and maximal occlusal force. Associations between MoCA-J scores and occlusal force were investigated via bivariate and multivariate analyses. Education level, financial status, depression score, and intake of green and yellow vegetables, as well as number of teeth and occlusal force, were significantly correlated with MoCA-J scores in both age groups. Among individuals aged 80 years, CRP and periodontal status were weakly but significantly associated with MoCA-J score. After controlling for all significant variables via bivariate analyses, the correlation between maximal occlusal force and cognitive function persisted. A path analysis confirmed the hypothesis that cognitive function is associated with occlusal force directly as well as indirectly via food intake. After controlling for possible factors, maximal occlusal force was positively associated with cognitive function directly as well as indirectly through dietary intake.

Method of construction of transient from a cycle of neuronal recurrence equation

International Nuclear Information System (INIS)

Ndoundam, R.; Tchuente, M.

2005-11-01

We study the sequences generated by neuronal recurrence equations of the form x(n) = 1[Σ j k =1 a j x(n - j) - θ], where k is the size of memory (k represents the number of previous states x(n - 1), x(n - 2), ...,x(n - k) which intervene in the calculation of x(n)). We are interested in the number of steps (transient length) from an initial configuration to the cycle. We propose a method of construction of transient from a cycle generated by neuronal recurrence equation. We apply this method to build a neuronal recurrence equation with inhibitory memory of size (s+1)6m, whose dynamics contains an evolution of transient length (s + 1) x (5m + 2 + lcm(p 0 , p 1 , ..., p 1 , 3m - 1)) and a cycle of length (s + 1) x lcm(p 0 , p 1 , ..., p s-1 , 2m + 1) where lcm denotes the least common multiple, and p 0 , p 1 , ..., p s-1 are prime numbers lying between 2m and 3m. (author)

Forecasting of indirect consumables for a Job Shop

Science.gov (United States)

Shakeel, M.; Khan, S.; Khan, W. A.

2016-08-01

A job shop has an arrangement where similar machines (Direct consumables) are grouped together and use indirect consumables to produce a product. The indirect consumables include hack saw blades, emery paper, painting brush etc. The job shop is serving various orders at a particular time for the optimal operation of job shop. Forecasting is required to predict the demand of direct and indirect consumables in a job shop. Forecasting is also needed to manage lead time, optimize inventory cost and stock outs. The objective of this research is to obtain the forecast for indirect consumables. The paper shows how job shop can manage their indirect consumables more accurately by establishing a new technique of forecasting. This results in profitable use of job shop by multiple users.

7 CFR 58.316 - Conventional churns.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Conventional churns. 58.316 Section 58.316 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....316 Conventional churns. Churns shall be constructed of aluminum, stainless steel or equally corrosion...

46 CFR 58.01-10 - Fuel oil.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Fuel oil. 58.01-10 Section 58.01-10 Shipping COAST GUARD... SYSTEMS General Requirements § 58.01-10 Fuel oil. (a) The following limits apply to the use of oil as fuel: (1) Except as otherwise permitted by this section, no fuel oil with a flashpoint of less than 60 °C...

The nuclear fuel cycle

International Nuclear Information System (INIS)

Patarin, L.

2002-01-01

This book treats of the different aspects of the industrial operations linked with the nuclear fuel, before and after its use in nuclear reactors. The basis science of this nuclear fuel cycle is chemistry. Thus a recall of the elementary notions of chemistry is given in order to understand the phenomena involved in the ore processing, in the isotope enrichment, in the fabrication of fuel pellets and rods (front-end of the cycle), in the extraction of recyclable materials (residual uranium and plutonium), and in the processing and conditioning of wastes (back-end of the fuel cycle). Nuclear reactors produce about 80% of the French electric power and the Cogema group makes 40% of its turnover at the export. Thus this book contains also some economic and geopolitical data in order to clearly position the stakes. The last part, devoted to the management of wastes, presents the solutions already operational and also the research studies in progress. (J.S.)

7 CFR 58.312 - Churn rooms.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Churn rooms. 58.312 Section 58.312 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....312 Churn rooms. Churn rooms in addition to proper construction and sanitation shall be so equipped...

20 CFR 617.58 - Unemployment insurance.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Unemployment insurance. 617.58 Section 617.58 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR TRADE ADJUSTMENT ASSISTANCE... Unemployment insurance. Unemployment insurance payable to an adversely affected worker shall not be denied or...

7 CFR 58.514 - Container fillers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Container fillers. 58.514 Section 58.514 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....514 Container fillers. Shall comply with the 3-A Sanitary Standards for Equipment for Packaging Frozen...

Proteins YlaJ and YhcN contribute to the efficiency of spore germination in Bacillus subtilis.

Science.gov (United States)

Johnson, Christian L; Moir, Anne

2017-04-01

The YlaJ and YhcN spore lipoproteins of Bacillus subtilis contain a common domain, and are of unknown function. Homologues of YlaJ or YhcN are widespread in Bacilli and are also encoded in those Clostridia that use cortex lytic enzymes SleB and CwlJ for cortex hydrolysis during germination. In B. subtilis, we report that single and double mutants lacking YlaJ and/or YhcN show a reduced rate of spore germination in L-alanine, with a delay in loss of heat resistance, release of dipicolinic acid and OD fall. If B. subtilis spores lack the cortex lytic enzyme CwlJ, spore cortex degradation and subsequent outgrowth to form colonies is strictly dependent on the other cortex lytic enzyme SleB, allowing a test of SleB function; in a cwlJ mutant background, the combined loss of both ylaJ and yhcN genes resulted in a spore population in which only 20% of spores germinated and outgrew to form colonies, suggesting that SleB activity is compromised. YlaJ and YhcN have a role in germination that is not yet well defined, but these proteins are likely to contribute, directly or indirectly, to early events in germination, including effective SleB function. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Impact of nucleic acid self-alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions

International Nuclear Information System (INIS)

Vavřinská, Andrea; Zelinka, Jiří; Šebera, Jakub; Sychrovský, Vladimír; Fiala, Radovan; Boelens, Rolf; Sklenář, Vladimír; Trantírek, Lukáš

2016-01-01

Heteronuclear and homonuclear direct (D) and indirect (J) spin–spin interactions are important sources of structural information about nucleic acids (NAs). The Hamiltonians for the D and J interactions have the same functional form; thus, the experimentally measured apparent spin–spin coupling constant corresponds to a sum of J and D. In biomolecular NMR studies, it is commonly presumed that the dipolar contributions to Js are effectively canceled due to random molecular tumbling. However, in strong magnetic fields, such as those employed for NMR analysis, the tumbling of NA fragments is anisotropic because the inherent magnetic susceptibility of NAs causes an interaction with the external magnetic field. This motional anisotropy is responsible for non-zero D contributions to Js. Here, we calculated the field-induced D contributions to 33 structurally relevant scalar coupling constants as a function of magnetic field strength, temperature and NA fragment size. We identified two classes of Js, namely 1 J CH and 3 J HH couplings, whose quantitative interpretation is notably biased by NA motional anisotropy. For these couplings, the magnetic field-induced dipolar contributions were found to exceed the typical experimental error in J-coupling determinations by a factor of two or more and to produce considerable over- or under-estimations of the J coupling-related torsion angles, especially at magnetic field strengths >12 T and for NA fragments longer than 12 bp. We show that if the non-zero D contributions to J are not properly accounted for, they might cause structural artifacts/bias in NA studies that use solution NMR spectroscopy

Reassessing the Potential Activities of Plant CGI-58 Protein

Science.gov (United States)

Khatib, Abdallah; Arhab, Yani; Bentebibel, Assia; Abousalham, Abdelkarim; Noiriel, Alexandre

2016-01-01

Comparative Gene Identification-58 (CGI-58) is a widespread protein found in animals and plants. This protein has been shown to participate in lipolysis in mice and humans by activating Adipose triglyceride lipase (ATGL), the initial enzyme responsible for the triacylglycerol (TAG) catabolism cascade. Human mutation of CGI-58 is the cause of Chanarin-Dorfman syndrome, an orphan disease characterized by a systemic accumulation of TAG which engenders tissue disorders. The CGI-58 protein has also been shown to participate in neutral lipid metabolism in plants and, in this case, a mutation again provokes TAG accumulation. Although its roles as an ATGL coactivator and in lipid metabolism are quite clear, the catalytic activity of CGI-58 is still in question. The acyltransferase activities of CGI-58 have been speculated about, reported or even dismissed and experimental evidence that CGI-58 expressed in E. coli possesses an unambiguous catalytic activity is still lacking. To address this problem, we developed a new set of plasmids and site-directed mutants to elucidate the in vivo effects of CGI-58 expression on lipid metabolism in E. coli. By analyzing the lipid composition in selected E. coli strains expressing CGI-58 proteins, and by reinvestigating enzymatic tests with adequate controls, we show here that recombinant plant CGI-58 has none of the proposed activities previously described. Recombinant plant and mouse CGI-58 both lack acyltransferase activity towards either lysophosphatidylglycerol or lysophosphatidic acid to form phosphatidylglycerol or phosphatidic acid and recombinant plant CGI-58 does not catalyze TAG or phospholipid hydrolysis. However, expression of recombinant plant CGI-58, but not mouse CGI-58, led to a decrease in phosphatidylglycerol in all strains of E. coli tested, and a mutation of the putative catalytic residues restored a wild-type phenotype. The potential activities of plant CGI-58 are subsequently discussed. PMID:26745266

Reassessing the Potential Activities of Plant CGI-58 Protein.

Directory of Open Access Journals (Sweden)

Abdallah Khatib

Full Text Available Comparative Gene Identification-58 (CGI-58 is a widespread protein found in animals and plants. This protein has been shown to participate in lipolysis in mice and humans by activating Adipose triglyceride lipase (ATGL, the initial enzyme responsible for the triacylglycerol (TAG catabolism cascade. Human mutation of CGI-58 is the cause of Chanarin-Dorfman syndrome, an orphan disease characterized by a systemic accumulation of TAG which engenders tissue disorders. The CGI-58 protein has also been shown to participate in neutral lipid metabolism in plants and, in this case, a mutation again provokes TAG accumulation. Although its roles as an ATGL coactivator and in lipid metabolism are quite clear, the catalytic activity of CGI-58 is still in question. The acyltransferase activities of CGI-58 have been speculated about, reported or even dismissed and experimental evidence that CGI-58 expressed in E. coli possesses an unambiguous catalytic activity is still lacking. To address this problem, we developed a new set of plasmids and site-directed mutants to elucidate the in vivo effects of CGI-58 expression on lipid metabolism in E. coli. By analyzing the lipid composition in selected E. coli strains expressing CGI-58 proteins, and by reinvestigating enzymatic tests with adequate controls, we show here that recombinant plant CGI-58 has none of the proposed activities previously described. Recombinant plant and mouse CGI-58 both lack acyltransferase activity towards either lysophosphatidylglycerol or lysophosphatidic acid to form phosphatidylglycerol or phosphatidic acid and recombinant plant CGI-58 does not catalyze TAG or phospholipid hydrolysis. However, expression of recombinant plant CGI-58, but not mouse CGI-58, led to a decrease in phosphatidylglycerol in all strains of E. coli tested, and a mutation of the putative catalytic residues restored a wild-type phenotype. The potential activities of plant CGI-58 are subsequently discussed.

Cell Cycle Regulation of Stem Cells by MicroRNAs.

Science.gov (United States)

Mens, Michelle M J; Ghanbari, Mohsen

2018-06-01

MicroRNAs (miRNAs) are a class of small non-coding RNA molecules involved in the regulation of gene expression. They are involved in the fine-tuning of fundamental biological processes such as proliferation, differentiation, survival and apoptosis in many cell types. Emerging evidence suggests that miRNAs regulate critical pathways involved in stem cell function. Several miRNAs have been suggested to target transcripts that directly or indirectly coordinate the cell cycle progression of stem cells. Moreover, previous studies have shown that altered expression levels of miRNAs can contribute to pathological conditions, such as cancer, due to the loss of cell cycle regulation. However, the precise mechanism underlying miRNA-mediated regulation of cell cycle in stem cells is still incompletely understood. In this review, we discuss current knowledge of miRNAs regulatory role in cell cycle progression of stem cells. We describe how specific miRNAs may control cell cycle associated molecules and checkpoints in embryonic, somatic and cancer stem cells. We further outline how these miRNAs could be regulated to influence cell cycle progression in stem cells as a potential clinical application.

Direct and indirect punishment among strangers in the field.

Science.gov (United States)

Balafoutas, Loukas; Nikiforakis, Nikos; Rockenbach, Bettina

2014-11-11

Many interactions in modern human societies are among strangers. Explaining cooperation in such interactions is challenging. The two most prominent explanations critically depend on individuals' willingness to punish defectors: In models of direct punishment, individuals punish antisocial behavior at a personal cost, whereas in models of indirect reciprocity, they punish indirectly by withholding rewards. We investigate these competing explanations in a field experiment with real-life interactions among strangers. We find clear evidence of both direct and indirect punishment. Direct punishment is not rewarded by strangers and, in line with models of indirect reciprocity, is crowded out by indirect punishment opportunities. The existence of direct and indirect punishment in daily life indicates the importance of both means for understanding the evolution of cooperation.

24 CFR 983.58 - Environmental review.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Environmental review. 983.58... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Selection of PBV Owner Proposals § 983.58 Environmental review. (a) HUD environmental regulations. Activities under the PBV program are subject to HUD environmental...

7 CFR 58.427 - Paraffin tanks.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Paraffin tanks. 58.427 Section 58.427 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....427 Paraffin tanks. The metal tank should be adequate in size, have wood rather than metal racks to...

The combination of an Environmental Management System and Life Cycle Assessment at the territorial level

Energy Technology Data Exchange (ETDEWEB)

Mazzi, Anna; Toniolo, Sara; Catto, Stella; De Lorenzi, Valentina; Scipioni, Antonio, E-mail: scipioni@unipd.it

2017-03-15

A framework to include a Life Cycle Assessment in the significance evaluation of the environmental aspects of an Environmental Management System has been studied for some industrial sectors, but there is a literature gap at the territorial level, where the indirect impact assessment is crucial. To overcome this criticality, our research proposes the Life Cycle Assessment as a framework to assess environmental aspects of public administration within an Environmental Management System applied at the territorial level. This research is structured in two parts: the design of a new methodological framework and the pilot application for an Italian municipality. The methodological framework designed supports Initial Environmental Analysis at the territorial level thanks to the results derived from the impact assessment phase. The pilot application in an Italian municipality EMAS registered demonstrates the applicability of the framework and its effectiveness in evaluating the environmental impact assessment for direct and indirect aspects. Through the discussion of the results, we underline the growing knowledge derived by this research in terms of the reproducibility and consistency of the criteria to define the significance of the direct and indirect environmental aspects for a local public administration. - Highlights: • The combination between Environmental Management System and LCA is studied. • A methodological framework is elaborated and tested at the territorial level. • Life Cycle Impact Assessment supports the evaluation of aspects significance. • The framework assures consistency of evaluation criteria on the studied territory.

The combination of an Environmental Management System and Life Cycle Assessment at the territorial level

International Nuclear Information System (INIS)

Mazzi, Anna; Toniolo, Sara; Catto, Stella; De Lorenzi, Valentina; Scipioni, Antonio

2017-01-01

A framework to include a Life Cycle Assessment in the significance evaluation of the environmental aspects of an Environmental Management System has been studied for some industrial sectors, but there is a literature gap at the territorial level, where the indirect impact assessment is crucial. To overcome this criticality, our research proposes the Life Cycle Assessment as a framework to assess environmental aspects of public administration within an Environmental Management System applied at the territorial level. This research is structured in two parts: the design of a new methodological framework and the pilot application for an Italian municipality. The methodological framework designed supports Initial Environmental Analysis at the territorial level thanks to the results derived from the impact assessment phase. The pilot application in an Italian municipality EMAS registered demonstrates the applicability of the framework and its effectiveness in evaluating the environmental impact assessment for direct and indirect aspects. Through the discussion of the results, we underline the growing knowledge derived by this research in terms of the reproducibility and consistency of the criteria to define the significance of the direct and indirect environmental aspects for a local public administration. - Highlights: • The combination between Environmental Management System and LCA is studied. • A methodological framework is elaborated and tested at the territorial level. • Life Cycle Impact Assessment supports the evaluation of aspects significance. • The framework assures consistency of evaluation criteria on the studied territory.

Thermo-economic performance of HTGR Brayton power cycles

International Nuclear Information System (INIS)

Linares, J. L.; Herranz, L. E.; Moratilla, B. Y.; Fernandez-Perez, A.

2008-01-01

High temperature reached in High and Very High Temperature Reactors (VHTRs) results in thermal efficiencies substantially higher than those of actual nuclear power plants. A number of studies mainly driven by achieving optimum thermal performance have explored several layout. However, economic assessments of cycle power configurations for innovative systems, although necessarily uncertain at this time, may bring valuable information in relative terms concerning power cycle optimization. This paper investigates the thermal and economic performance direct Brayton cycles. Based on the available parameters and settings of different designs of HTGR power plants (GTHTR-300 and PBMR) and using the first and second laws of thermodynamics, the effects of compressor inter-cooling and of the compressor-turbine arrangement (i.e., single vs. multiple axes) on thermal efficiency have been estimated. The economic analysis has been based on the El-Sayed methodology and on the indirect derivation of the reactor capital investment. The results of the study suggest that a 1-axis inter-cooled power cycle has a similar thermal performance to the 3-axes one (around 50%) and, what's more, it is substantially less taxed. A sensitivity study allowed assessing the potential impact of optimizing several variables on cycle performance. Further than that, the cycle components costs have been estimated and compared. (authors)

Homogeneous Thorium Fuel Cycles in Candu Reactors

Energy Technology Data Exchange (ETDEWEB)

Hyland, B.; Dyck, G.R.; Edwards, G.W.R.; Magill, M. [Chalk River Laboratories, Atomic Energy of Canada Limited (Canada)

2009-06-15

of Canada Report, AECL-11937. 2. P.G. Boczar, P.S.W. Chan, G.R. Dyck, R.J. Ellis, R.T. Jones, J.D. Sullivan and P. Taylor, 'Thorium Fuel-Cycle Studies for Candu Reactors', 1998. Published in Thorium Fuel Utilization: Options and Trends, IAEA-TECDOC-1319, 2002 November. 3. P.G. Boczar, G.R. Dyck, P.S.W. Chan and D.B. Buss, 'Recent Advances in Thorium Fuel Cycles for Candu Reactors', 1999. Published in Thorium Fuel Utilization: Options and Trends, IAEA-TECDOC- 1319, 2002 November. (authors)

JUSTIFICATION FOR INDIRECT DISCRIMINATION IN EU

Directory of Open Access Journals (Sweden)

Cătălina-Adriana Ivănuş

2014-11-01

Full Text Available The right to non-discrimination is very important for a civilized society. EU legislation establishes direct and indirect discrimination, harassment, sexual harassment, instruction to discriminate and any less favourable treatment of a woman related to pregnancy or maternity leave as forms of discrimination. The law and the Court of Justice permit the justification of indirect discrimination.

JUSTIFICATION FOR INDIRECT DISCRIMINATION IN EU

OpenAIRE

Cătălina-Adriana Ivănuş

2014-01-01

The right to non-discrimination is very important for a civilized society. EU legislation establishes direct and indirect discrimination, harassment, sexual harassment, instruction to discriminate and any less favourable treatment of a woman related to pregnancy or maternity leave as forms of discrimination. The law and the Court of Justice permit the justification of indirect discrimination.

7 CFR 58.61 - Political activity.

Science.gov (United States)

2010-01-01

....61 Political activity. All inspectors or graders are forbidden during the period of their respective appointments or licenses to take an active part in political management or in political campaigns. Political... 7 Agriculture 3 2010-01-01 2010-01-01 false Political activity. 58.61 Section 58.61 Agriculture...

Numerical analysis of the heat and mass transfer processes in selected M-Cycle heat exchangers for the dew point evaporative cooling

International Nuclear Information System (INIS)

Pandelidis, Demis; Anisimov, Sergey

2015-01-01

Highlights: • The comparative numerical study of the eight M-Cycle heat exchangers was presented. • The mathematical model is compared against the experimental data. • The results show, that the original M-Cycle heat and mass exchanger can be improved. • The effectiveness of the heat and mass exchangers depends strongly on the inlet air parameters. - Abstract: This paper investigates a mathematical simulation of heat and mass transfer in eight different types of the Maisotsenko Cycle (M-Cycle) heat and mass exchangers (HMXs) used for indirect evaporative air cooling. A two-dimensional heat and mass transfer model is developed to perform the thermal calculations of the indirect evaporative cooling process and quantifying the overall performance. The mathematical model was validated against experimental data. A numerical simulation reveals many unique features of the considered HMXs, enabling an accurate prediction of their performance. Results of the model allow for comparison of the analyzed devices in order to improve the performance of the original HMX

Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break-inducing agents

International Nuclear Information System (INIS)

Holgersson, Asa; Heiden, Thomas; Castro, Juan; Edgren, Margareta R.; Lewensohn, Rolf; Meijer, Annelie E.

2005-01-01

Purpose: To investigate and compare the cell cycle progression in relation to cell death in the human glioma cell lines, M059J and M059K, after exposure to DNA double-strand break-inducing agents. Methods and materials: The M059J and M059K cells, deficient and proficient in the catalytic subunit of the DNA-dependent protein kinase, respectively, were exposed to 1 and 4 Gy of photons or accelerated nitrogen ions. In addition, M059J and M059K cells were treated with 10 and 40 μg/mL of bleomycin for 30 min, respectively. Cell cycle progression, monitored by DNA flow cytometry, was measured up to 72 h after treatment. Results: M059J, but not M059K, cells displayed G 2 /M accumulation after low linear energy transfer irradiation. High linear energy transfer radiation exposure however, resulted in a substantial increase of M059K cells in the G 2 /M phase detected at 48 h. At 72 h, the number of cells in the G 2 /M phase was equivalent to its control. M059J cells accumulated mainly in S phase after high linear energy transfer irradiation. In contrast to M059K, M059J cells were still blocked at 72 h. Bleomycin induced G 2 /M accumulation for both M059J and M059K cells detected 24 h after treatment. At 48 h, the percentage of bleomycin-treated M059J cells in G 2 /M phase remained high, and the number of M059K cells had decreased to control levels. Neither cell line showed cell cycle arrest (≤10 h) after exposure to these agents. Conclusion: Distinct cell cycle block and release is dependent on the complexity of the induced DNA damage and the presence of the DNA-dependent protein kinase catalytic subunit

Precooling With Crushed Ice: As Effective as Heat Acclimation at Improving Cycling Time-Trial Performance in the Heat.

Science.gov (United States)

Zimmermann, Matthew; Landers, Grant; Wallman, Karen; Kent, Georgina

2018-02-01

This study compared the effects of precooling (ice ingestion) and heat-acclimation training on cycling time-trial (CTT) performance in the heat. Fifteen male cyclists/triathletes completed two 800-kJ CTTs in the heat, with a 12-d training program in between. Initially, all participants consumed 7 g/kg of water (22°C) in 30 min before completing an 800-kJ CTT in hot, humid conditions (pre-CTT) (35°C, 50% relative humidity [RH]). Participants were then split into 2 groups, with the precooling group (n = 7) training in thermoneutral conditions and then undergoing precooling with ice ingestion (7 g/kg, 1°C) prior to the final CTT (post-CTT) and the heat-acclimation group (n = 8) training in hot conditions (35°C, 50% RH) and consuming water (7 g/kg) prior to post-CTT. After training in both conditions, improvement in CTT time was deemed a likely positive benefit (precooling -166 ± 133 s, heat acclimation -105 ± 62 s), with this result being similar between conditions (d = 0.22, -0.68-1.08 90% confidence interval [CI]). Core temperature for post-CTT was lower in precooling than in heat acclimation from 20 min into the precooling period until the 100-kJ mark of the CTT (d > 0.98). Sweat onset occurred later in precooling (250 ± 100 s) than in heat acclimation (180 ± 80 s) for post-CTT (d = 0.65, -0.30-1.50 90% CI). Thermal sensation was lower at the end of the precooling period prior to post-CTT for the precooling trial than with heat acclimation (d = 1.24, 0.90-1.58 90% CI). Precooling with ice ingestion offers an alternative method of improving endurance-cycling performance in hot conditions if heat acclimation cannot be attained.

An unexpected role for mixotrophs in the response of peatland carbon cycling to climate warming.

Science.gov (United States)

Jassey, Vincent E J; Signarbieux, Constant; Hättenschwiler, Stephan; Bragazza, Luca; Buttler, Alexandre; Delarue, Frédéric; Fournier, Bertrand; Gilbert, Daniel; Laggoun-Défarge, Fatima; Lara, Enrique; Mills, Robert T E; Mitchell, Edward A D; Payne, Richard J; Robroek, Bjorn J M

2015-11-25

Mixotrophic protists are increasingly recognized for their significant contribution to carbon (C) cycling. As phototrophs they contribute to photosynthetic C fixation, whilst as predators of decomposers, they indirectly influence organic matter decomposition. Despite these direct and indirect effects on the C cycle, little is known about the responses of peatland mixotrophs to climate change and the potential consequences for the peatland C cycle. With a combination of field and microcosm experiments, we show that mixotrophs in the Sphagnum bryosphere play an important role in modulating peatland C cycle responses to experimental warming. We found that five years of consecutive summer warming with peaks of +2 to +8°C led to a 50% reduction in the biomass of the dominant mixotrophs, the mixotrophic testate amoebae (MTA). The biomass of other microbial groups (including decomposers) did not change, suggesting MTA to be particularly sensitive to temperature. In a microcosm experiment under controlled conditions, we then manipulated the abundance of MTA, and showed that the reported 50% reduction of MTA biomass in the field was linked to a significant reduction of net C uptake (-13%) of the entire Sphagnum bryosphere. Our findings suggest that reduced abundance of MTA with climate warming could lead to reduced peatland C fixation.

Serological discrimination by indirect enzyme immunoassay between the antibody response to Brucella sp and Yersinia enterocolitica O : 9 in cattle and pigs

DEFF Research Database (Denmark)

Nielsen, K.; Smith, P.; Yu, W.

2006-01-01

A rapid, inexpensive and rugged serological test that distinguishes cattle and swine infected with Brucella sp. or Yersinia enterocolitica O:9 is described. The test protocol, which is an indirect enzyme immunoassay uses a high concentration of divalent cation chelating agents to minimize binding...... with Brucella sp. Sera from 58 cattle and 38 swine exposed to Y. enterocolitica O:9 were negative while only 20 sera from 121 'false positive' reactors of unspecified origin gave low level positive reactions, eliminating 84% of the false positive reactions. Crown...

7 CFR 58.315 - Continuous churns.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Continuous churns. 58.315 Section 58.315 Agriculture....315 Continuous churns. All product contact surfaces of the churn and related equipment shall be of..., Rubber, and Rubber-Like Materials. All product contact surfaces of the churn and related equipment shall...

Hypernuclei and strangeness physics programme at J-PARC

International Nuclear Information System (INIS)

Nagae, Tomofumi

2009-01-01

Full text: The construction of Japan Proton Accelerator Research Complex (J-PARC) is completed in 2009. The J-PARC accelerators consist of a 181-MeV proton linac, a 3-GeV rapid-cycling proton synchrotron, and a 50-GeV main proton synchrotron. Now, the 3-GeV proton beam is used to produce spallation neutrons and slow muons for materials and life sciences. The 30-GeV proton beam from the main ring is used to produce high-intensity kaon beams and neutrino beam. Beam commissioning of the slow-extraction beam from the J- PARC main proton synchrotron started in January, 2009. The beam was successfully extracted and transported to the Hadron Experimental Hall on January 27. The first secondary-beam production was confirmed on February 11 at the K1.8-branch beam line in the hall. Although we need a lot of work to be completed before the beam would be available for experimental users, we believe this is the start of the J-PARC era to open new research fields in strangeness nuclear physics. The K - beams with the highest intensity in the world enable us to carry out various interesting experimental subjects; the (K - , K + ) missing-mass spectroscopy to discover hypernuclei, hypernuclear gamma-ray spectroscopy, search for kaonic nuclei, and so on. New detector systems such as the SKS+ spectrometer, Hyperball-J detector, and Cylindrical Detector System (CDS) are now in preparation. Present status of the experiments, our initial physics goals at J-PARC and the perspectives are discussed

Indirect Genetic Effects for group-housed animals

DEFF Research Database (Denmark)

Alemu, Setegn Worku

This thesis investigated social interactions in group-housed animals. The main findings of this thesis: 1) Statistical methods to estimate indirect genetic effects when interactions differ between kin vs. non-kin were developed. 2) Indirect genetic effects contribute a substantial amount...... of heritable variation for bite mark traits in group-housed min. 3) Indirect genetic effects estimation needs to take into account systematic interactions due to sex or kin for bite mark trait in group-housed min. 4) Genomic selection can be used to increase the response to selection for survival time in Brown...

The Grid Density Dependence of the Unsteady Pressures of the J-2X Turbines

Science.gov (United States)

Schmauch, Preston B.

2011-01-01

The J-2X engine was originally designed for the upper stage of the cancelled Crew Launch Vehicle. Although the Crew Launch Vehicle was cancelled the J-2X engine, which is currently undergoing hot-fire testing, may be used on future programs. The J-2X engine is a direct descendent of the J-2 engine which powered the upper stage during the Apollo program. Many changes including a thrust increase from 230K to 294K lbf have been implemented in this engine. As part of the design requirements, the turbine blades must meet minimum high cycle fatigue factors of safety for various vibrational modes that have resonant frequencies in the engine's operating range. The unsteady blade loading is calculated directly from CFD simulations. A grid density study was performed to understand the sensitivity of the spatial loading and the magnitude of the on blade loading due to changes in grid density. Given that the unsteady blade loading has a first order effect on the high cycle fatigue factors of safety, it is important to understand the level of convergence when applying the unsteady loads. The convergence of the unsteady pressures of several grid densities will be presented for various frequencies in the engine's operating range.

Desensitizing bioactive agents improves bond strength of indirect resin-cemented restorations: preliminary results

Directory of Open Access Journals (Sweden)

Fernanda de Carvalho Panzeri Pires-de-Souza

2007-04-01

Full Text Available OBJECTIVE: The aim of this study was to assess the bond strength of indirect composite restorations cemented with a resin-based cement associated with etch-and-rinse and self-etching primer adhesive systems to dentin treated or not with a bioactive material. MATERIALS AND METHOD: Twenty bovine incisor crowns had the buccal enamel removed and the dentin ground flat. The teeth were assigned to 4 groups (n=5: Group I: acid etching + Prime & Bond NT (Dentsply; Group II: application of a bioactive glass (Biosilicato®+ acid etching + Prime & Bond NT; Group III: One-up Bond F (J Morita; Group IV: Biosilicato® + One-up Bond F. Indirect composite resin (Artglass, Kulzer cylinders (6x10mm were fabricated and cemented to the teeth with a dual-cure resin-based cement (Enforce, Dentsply. After cementation, the specimens were stored in artificial saliva at 37ºC for 30 days and thereafter tested in tensile strength in a universal testing machine (EMIC with 50 kgf load cell at a crosshead speed of 1 mm/min. Failure modes were assessed under scanning electron microscopy. Data were analyzed statistically by ANOVA and Tukey's test (95% level of confidence. RESULTS: Groups I, II and III had statistically similar results (p>0.05. Group IV had statistically significant higher bond strength means (p<0.05 than the other groups. The analysis of the debonded surfaces showed a predominance of adhesive failure mode for Group III and mixed failure mode for the other groups. CONCLUSION: The use of desensitizing agent did not affect negatively the bonding of the indirect composite restorations to dentin, independently of the tested adhesive systems.

Direct and indirect costs of dinitrogen fixation in Crocosphaera watsonii WH8501 and possible implications for the nitrogen cycle

Directory of Open Access Journals (Sweden)

Tobias eGroßkopf

2012-07-01

Full Text Available The recent detection of heterotrophic nitrogen (N2 fixation in deep waters of the southern Californian and Peruvian OMZ questions our current understanding of marine N2 fixation as a process confined to oligotrophic surface waters of the oceans. In experiments with Crocosphaera watsonii WH8501, a marine unicellular diazotrophic (N2-fixing cyanobacterium, we demonstrated that the presence of high nitrate concentrations (up to 800 µM had no inhibitory effect on growth and N2 fixation over a period of two weeks. In contrast, the environmental oxygen concentration significantly influenced rates of N2 fixation and respiration, as well as carbon and nitrogen cellular content of C. watsonii over a 24 hour period. Cells grown under lowered oxygen atmosphere (5% had a higher nitrogenase activity and respired less carbon during the dark cycle than under normal oxygen atmosphere (20%. Respiratory oxygen drawdown during the dark period could be fully explained (104% by energetic needs due to basal metabolism and N2 fixation at low oxygen, while at normal oxygen these two processes could only account for 40% of the measured respiration rate. Our results revealed that under normal oxygen concentration most of the energetic costs during N2 fixation (~60% are not derived from the process of N2 fixation per se but rather from the indirect costs incurred for the removal of intracellular oxygen or by the reversal of oxidative damage (e.g. nitrogenase de novo synthesis. Theoretical calculations suggest a slight energetic advantage of N2 fixation relative to assimilatory nitrate uptake for heterotrophic and phototrophic growth, when oxygen supply is in balance with the oxygen requirement for cellular respiration (i.e. energy generation for basal metabolism and N2 fixation. Taken together our results imply the existence of a niche for diazotrophic organisms inside oxygen minimum zones, which are predicted to further expand in the future ocean.

7 CFR 58.220 - Drying systems.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Drying systems. 58.220 Section 58.220 Agriculture....220 Drying systems. (a) Spray dryers. Spray dryers shall be of a continuous discharge type and all... filter system shall comply with the applicable requirements of the 3-A Accepted Practices for Milk and...

New Approaches in Reuseable Booster System Life Cycle Cost Modeling

Science.gov (United States)

Zapata, Edgar

2013-01-01

This paper presents the results of a 2012 life cycle cost (LCC) study of hybrid Reusable Booster Systems (RBS) conducted by NASA Kennedy Space Center (KSC) and the Air Force Research Laboratory (AFRL). The work included the creation of a new cost estimating model and an LCC analysis, building on past work where applicable, but emphasizing the integration of new approaches in life cycle cost estimation. Specifically, the inclusion of industry processes/practices and indirect costs were a new and significant part of the analysis. The focus of LCC estimation has traditionally been from the perspective of technology, design characteristics, and related factors such as reliability. Technology has informed the cost related support to decision makers interested in risk and budget insight. This traditional emphasis on technology occurs even though it is well established that complex aerospace systems costs are mostly about indirect costs, with likely only partial influence in these indirect costs being due to the more visible technology products. Organizational considerations, processes/practices, and indirect costs are traditionally derived ("wrapped") only by relationship to tangible product characteristics. This traditional approach works well as long as it is understood that no significant changes, and by relation no significant improvements, are being pursued in the area of either the government acquisition or industry?s indirect costs. In this sense then, most launch systems cost models ignore most costs. The alternative was implemented in this LCC study, whereby the approach considered technology and process/practices in balance, with as much detail for one as the other. This RBS LCC study has avoided point-designs, for now, instead emphasizing exploring the trade-space of potential technology advances joined with potential process/practice advances. Given the range of decisions, and all their combinations, it was necessary to create a model of the original model

New Approaches in Reusable Booster System Life Cycle Cost Modeling

Science.gov (United States)

Zapata, Edgar

2013-01-01

This paper presents the results of a 2012 life cycle cost (LCC) study of hybrid Reusable Booster Systems (RBS) conducted by NASA Kennedy Space Center (KSC) and the Air Force Research Laboratory (AFRL). The work included the creation of a new cost estimating model and an LCC analysis, building on past work where applicable, but emphasizing the integration of new approaches in life cycle cost estimation. Specifically, the inclusion of industry processes/practices and indirect costs were a new and significant part of the analysis. The focus of LCC estimation has traditionally been from the perspective of technology, design characteristics, and related factors such as reliability. Technology has informed the cost related support to decision makers interested in risk and budget insight. This traditional emphasis on technology occurs even though it is well established that complex aerospace systems costs are mostly about indirect costs, with likely only partial influence in these indirect costs being due to the more visible technology products. Organizational considerations, processes/practices, and indirect costs are traditionally derived ("wrapped") only by relationship to tangible product characteristics. This traditional approach works well as long as it is understood that no significant changes, and by relation no significant improvements, are being pursued in the area of either the government acquisition or industry?s indirect costs. In this sense then, most launch systems cost models ignore most costs. The alternative was implemented in this LCC study, whereby the approach considered technology and process/practices in balance, with as much detail for one as the other. This RBS LCC study has avoided point-designs, for now, instead emphasizing exploring the trade-space of potential technology advances joined with potential process/practice advances. Given the range of decisions, and all their combinations, it was necessary to create a model of the original model

The menstrual cycle and sexual behavior: relationship to eating, exercise, sleep, and health patterns.

Science.gov (United States)

Brown, Susan G; Morrison, Lynn A; Calibuso, Marites J; Christiansen, Tess M

2008-01-01

Patterns of eating, exercise, sleep, and health were investigated across 180 menstrual cycles of 89 women who engaged in sex with a male (n = 45; cycles = 85), a female (n = 21; cycles = 37), or abstained from sex (n = 33; cycles = 58) from January 2005 to December 2007 (10 contributed to 2 groups). Cycles were divided into 5 phases based on their luteinizing hormone surges. Daily questionnaires and saliva for IgA and cortisol analyses were obtained. Women indicated that they ate more (p Sexually active women had lower cortisol and IgA levels than abstinent women (p = .02). Our study discovered, and confirmed, systematic differences in eating, sleeping, and health patterns across women's menstrual cycles.

Indirectness in Discourse: Ethnicity as Conversational Style.

Science.gov (United States)

Tannen, Deborah

1981-01-01

Examines social differences in expectations of indirectness in conversations between married couples, both Greek and Greek-American. Concludes that Greeks are more likely to expect indirectness in the context presented and that Greek-Americans have retained the Greek communicative patterns. (FL)

Manifestation of Aerosol Indirect Effects in Arctic Clouds

Science.gov (United States)

Lubin, D.; Vogelmann, A. M.

2009-12-01

The first aerosol indirect effect has traditionally been conceived as an enhancement of shortwave cloud reflectance in response to decreased effective droplet size at fixed liquid water path, as cloud nucleating aerosol becomes entrained in the cloud. The high Arctic, with its pervasive low-level stratiform cloud cover and frequent episodes of anthropogenic aerosol (Artic "haze"), has in recent years served as a natural laboratory for research on actual manifestations of aerosol indirect effects. This paper will review the surprising set of developments: (1) the detection of the indirect effect as a source of surface warming, rather than cooling, throughout early spring, (2) a transition to a cooling effect in late spring, corresponding to the beginning of the sea ice melt season, and (3) detection of an indirect effect during summer, outside of the "Arctic haze" season. This paper will also discuss measurements of spectral shortwave irradiance (350-2200 nm) made at Barrow, Alaska, during the U.S. Department of Energy's Indirect and Semi-Direct Aerosol Campaign (ISDAC), which reveal complications in our conception of the indirect effect related to the ice phase in Arctic stratiform clouds.

Report of the committee to review the use of J-13 well water in Nevada Nuclear Waste Storage Investigations

International Nuclear Information System (INIS)

Harrar, J.E.; Carley, J.F.; Isherwood, W.F.; Raber, E.

1990-01-01

The Waste Management Project Office of the Department of Energy conducted a special audit of the activities of the Nevada Nuclear Waste Storage Investigation Project at Livermore. It was noted that there never has been a comprehensive, well-documented examination of the basis for the use of J-13 water in the nuclear waste storage investigations. In each of the sections of This Report, an issue relating to the use of J-13 water has been addressed. 58 refs., 19 figs., 8 tabs

Smoking Cessation Is Associated With Lower Indirect Costs.

Science.gov (United States)

Baker, Christine L; Bruno, Marianna; Emir, Birol; Li, Vicky W; Goren, Amir

2018-06-01

This study quantified differences in indirect costs due to decreased work productivity between current and former smokers. Former smokers were further categorized by number of years since quitting to assess corresponding differences. Data on employed individuals were obtained from the 2013 US National Health and Wellness Survey (NHWS; N = 75,000). Indirect costs were calculated for current smokers and former smokers from weekly wages based on age and sex. The annual total indirect costs for current smokers were $1327.53, $1560.18, and $1839.87 higher than for those who quit 0 to 4 years, 5 to 10 years, and more than or equal to 11 years prior, respectively. There were no significant differences in mean total indirect costs between the former smoker groups. Current smokers showed significantly higher total annual indirect costs compared with former smokers, independently of the number of years since quitting smoking.

On the Relative Size of Direct and Indirect Taxation

OpenAIRE

Soldatos, Gerasimos T.

2014-01-01

Modifying the standard analytical apparatuses for direct and indirect tax evasion to incorporate forward indirect tax shift in a monopolistically competitive environment, this paper maintains that indirect tax evasion would exceed for sure direct tax evasion only under consumer risk neutrality and a tax policy zeroing the tax shift. Also, in the presence of tax evasion, there cannot be optimal direct-indirect tax mix, because tax evasion is accompanied by uncertainty and hence, nonlinearities...

Design of closed-loop nitrogen Joule-Thomson refrigeration cycle for 67 K with sub-atmospheric device

Energy Technology Data Exchange (ETDEWEB)

Lee, C.; Lee, J.; Jeong, S. [Cryogenic Engineering Laboratory, Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of)

2013-05-15

Closed-loop J-T (Joule-Thomson) refrigeration cycle is advantageous compared to common open loop N{sub 2} decompression system in terms of nitrogen consumption. In this study, two closed-loop pure N{sub 2} J-T refrigeration systems with sub-atmospheric device for cooling High Temperature Superconductor (HTS) power cable are investigated. J-T cooling systems include 2-stage compressor, 2-stage precooling cycle, J-T valve and a cold compressor or an auxiliary vacuum pump at the room temperature. The cold compressor and the vacuum pump are installed after the J-T valve to create sub-atmospheric condition. The temperature of 67 K is possible by lowering the pressure up to 24 kPa at the cold part. The optimized hydrocarbon mixed refrigerant (MR) J-T system is applied for precooling stage. The cold head of precooling MR J-T have the temperature from 120 K to 150 K. The various characteristics of cold compressor are investigated and applied to design parameter of the cold compressor. The Carnot efficiency of cold compressor system is calculated as 16.7% and that of vacuum pump system as 16.4%. The efficiency difference between the cold compressor system and the vacuum pump system is due to difference of enthalpy change at cryogenic temperature, enthalpy change at room temperature and different work load at the pre-cooling cycle. The efficiency of neon-nitrogen MR J-T system is also presented for comparison with the sub-atmospheric devices. These systems have several pros and cons in comparison to typical MR J-T systems such as vacuum line maintainability, system's COP and etc. In this paper, the detailed design of the subcooled N{sub 2} J-T systems are examined and some practical issues of the sub-atmospheric devices are discussed.

Menstrual cycle and its disorders in women with congenital heart disease

NARCIS (Netherlands)

Drenthen, Willem; Hoendermis, Elke S.; Moons, Philip; Heida, Karst Y.; Roos-Hesselink, Jolien W.; Mulder, Barbara J. M.; van Dijk, Arie P. J.; Vliegen, Hubert W.; Sollie, Krystyna M.; Berger, Rolf M. F.; Lely, A. Titia; Canobbio, Mary M.; Pieper, Petronella G.

2008-01-01

OBJECTIVES: To investigate the age at menarche, the prevalence of menstrual cycle (interval) disorders, and determinants in women with congenital heart disease (CHD). DESIGN: Using two CHD registries, 1802 (82%) of the 2196 women with CHD contacted (aged 18-58 years) provided written informed

Menstrual cycle and its disorders in women with congenital heart disease.

NARCIS (Netherlands)

Drenthen, W.; Hoendermis, E.S.; Moons, P.; Heida, K.Y.; Roos-Hesselink, J.W.; Mulder, B.J.M.; Dijk, A.P.J. van; Vliegen, H.W.; Sollie, K.M.; Berger, R.M.; Lely, A.T.; Canobbio, M.M.; Pieper, P.G.

2008-01-01

OBJECTIVES: To investigate the age at menarche, the prevalence of menstrual cycle (interval) disorders, and determinants in women with congenital heart disease (CHD). DESIGN: Using two CHD registries, 1802 (82%) of the 2196 women with CHD contacted (aged 18-58 years) provided written informed

40 CFR 430.58 - Best management practices (BMPs).

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Best management practices (BMPs). 430.58 Section 430.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT... § 430.58 Best management practices (BMPs). The definitions and requirements set forth in 40 CFR 430.03...

7 CFR 58.236 - Pasteurization and heat treatment.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Pasteurization and heat treatment. 58.236 Section 58... Service 1 Operations and Operating Procedures § 58.236 Pasteurization and heat treatment. All milk and... is handled according to sanitary conditions approved by the Administrator. (a) Pasteurization. (1...

Restoration of oscillation in network of oscillators in presence of direct and indirect interactions

Energy Technology Data Exchange (ETDEWEB)

Majhi, Soumen; Bera, Bidesh K. [Physics and Applied Mathematics Unit, Indian Statistical Institute, Kolkata-700108 (India); Bhowmick, Sourav K. [Department of Electronics, Asutosh College, Kolkata-700026 (India); Ghosh, Dibakar, E-mail: diba.ghosh@gmail.com [Physics and Applied Mathematics Unit, Indian Statistical Institute, Kolkata-700108 (India)

2016-10-23

The suppression of oscillations in coupled systems may lead to several unwanted situations, which requires a suitable treatment to overcome the suppression. In this paper, we show that the environmental coupling in the presence of direct interaction, which can suppress oscillation even in a network of identical oscillators, can be modified by introducing a feedback factor in the coupling scheme in order to restore the oscillation. We inspect how the introduction of the feedback factor helps to resurrect oscillation from various kinds of death states. We numerically verify the resurrection of oscillations for two paradigmatic limit cycle systems, namely Landau–Stuart and Van der Pol oscillators and also in generic chaotic Lorenz oscillator. We also study the effect of parameter mismatch in the process of restoring oscillation for coupled oscillators. - Highlights: • Amplitude death is observed using direct and indirect coupling. • Revival of oscillation using feedback parameter is discussed. • Restoration of oscillation is observed in limit cycle and chaotic systems.

Neutron to proton ratios of quasiprojectile and midrapidity emission in the 58Ni+58Ni reaction at 52 MeV/nucleon

International Nuclear Information System (INIS)

Theriault, D.; Vallee, A.; Gingras, L.; Larochelle, Y.; Roy, R.; April, A.; Beaulieu, L.; Grenier, F.; Lemieux, F.; Moisan, J.; St-Pierre, C.; Turbide, S.; Samri, M.; Borderie, B.; Rivet, M. F.; Bougault, R.; Colin, J.; Cussol, D.; Durand, D.; Lecolley, J.F.

2005-01-01

By combining data from a charged particle 58 Ni+ 58 Ni experiment at 52 MeV/nucleon with an 36 Ar+ 58 Ni experiment at 50 MeV/nucleon for which free neutrons have been detected, an increase in the neutron to proton ratio of the whole nuclear material at midrapidity has been experimentally observed in the reaction 58 Ni+ 58 Ni at 52 MeV/nucleon. The neutron-to-proton ratio of the quasi-projectile emission is analyzed for the same reactions and is seen to decrease below the ratio of the initial system. Those observations suggest that an asymmetric exchange of neutrons and protons between the quasiprojectile and the midrapidity region exists

System markets: Indirect network effects in action, or inaction?

NARCIS (Netherlands)

J.L.G. Binken (Jeroen)

2010-01-01

textabstractIn this dissertation, I empirically examine system markets up close. More specifically I examine indirect network effects, both demand-side and supply-side indirect network effects. Indirect network effects are the source of positive feedback in system markets, or so network effect

21 CFR 870.3640 - Indirect pacemaker generator function analyzer.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Indirect pacemaker generator function analyzer... Indirect pacemaker generator function analyzer. (a) Identification. An indirect pacemaker generator function analyzer is an electrically powered device that is used to determine pacemaker function or...

7 CFR 58.731 - Closing and sealing containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Closing and sealing containers. 58.731 Section 58.731... Procedures § 58.731 Closing and sealing containers. Pouches, liners, or containers having product contact... means, so as to assure against contamination. Each container in addition to other required labeling...

7 CFR 58.5 - Where service is offered.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Where service is offered. 58.5 Section 58.5 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Grading Service § 58.5 Where service is offered. Subject to the provisions of this part, inspection or...

7 CFR 58.522 - Reconstituting nonfat dry milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Reconstituting nonfat dry milk. 58.522 Section 58.522 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Procedures § 58.522 Reconstituting nonfat dry milk. Nonfat dry milk shall be reconstituted in a sanitary...

7 CFR 58.37 - Financial interest of licensees.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Financial interest of licensees. 58.37 Section 58.37 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Inspectors Or Graders § 58.37 Financial interest of licensees. No licensee shall render service on any...

Preliminary thermodynamic study of regenerative Otto based cycles with zero NOx emissions operating with adiabatic and polytropic expansion

International Nuclear Information System (INIS)

Garcia, Ramon Ferreiro; Carril, Jose Carbia; Romero Gomez, Javier; Romero Gomez, Manuel

2016-01-01

Highlights: • Efficient polytropic expansion based Otto cycle. • Thermal efficiency is due to the inherent regeneration. • Low temperature combustion with zero NOx emissions. - Abstract: The aim of the paper is to demonstrate that a regenerative Otto cycle with adiabatic or polytropic expansion can achieve improved performance over traditional Otto engines, even exceeding the Carnot factor. Thus, the work deals with a novel regenerative Otto based internal combustion engine which differs from the conventional Otto thermal cycles in that the process of heat conversion into mechanical work is performed obeying a polytropic path function instead of the conventional adiabatic expansion without regeneration. Design characteristics concern the fact that combustion at constant volume is carried out undergoing large air excess so that the top combustion temperature is significantly lower than in conventional Otto cycles and consequently NOx emissions are neglected. Furthermore, during the polytropic expansion based path function, heat is absorbed by being submitted to a controlled heat flow rate, to achieve the desired polytropic expansion. The analysis of the regenerative Otto based on polytropic expansion is presented and results are compared with a regenerative Otto based on the adiabatic expansion and CF. The results show that a relevant advantage of the proposed regenerative Otto with polytropic expansion over the regenerative Otto cycle with adiabatic expansion involves performance enhancement within a wide range of combustion pressures, temperatures and regeneration capacities. Thus, thermal efficiency and specific work as function of the top combustion pressure ranges are of 71.95–58.43% and 143.5–173.6 kJ/kg respectively, when combustion pressures vary between 105 kPa and 200 kPa and CF is 60.8% (lower than the thermal efficiency). The successful results involving a compact engine structure, technically and economically viable, promises a new generation

Measurement of the leptonic decay width of J/ψ using initial state radiation

Directory of Open Access Journals (Sweden)

M. Ablikim

2016-10-01

Full Text Available Using a data set of 2.93 fb−1 taken at a center-of-mass energy of s=3.773 GeV with the BESIII detector at the BEPCII collider, we measure the process e+e−→J/ψγ→μ+μ−γ and determine the product of the branching fraction and the electronic width Bμμ⋅Γee=(333.4±2.5stat±4.4sys eV. Using the earlier-published BESIII result for Bμμ=(5.973±0.007stat±0.037sys%, we derive the J/ψ electronic width Γee=(5.58±0.05stat±0.08sys keV.

Suppressive activities and mechanisms of ugonin J on vascular smooth muscle cells and balloon angioplasty-induced neointimal hyperplasia.

Science.gov (United States)

Pan, Chun-Hsu; Li, Pei-Chuan; Chien, Yi-Chung; Yeh, Wan-Ting; Liaw, Chih-Chuang; Sheu, Ming-Jyh; Wu, Chieh-Hsi

2018-02-01

Neointimal hyperplasia (or restenosis) is primarily attributed to excessive proliferation and migration of vascular smooth muscle cells (VSMCs). In this study, we investigated the inhibitory effects and mechanisms of ugonin J on VSMC proliferation and migration as well as neointimal formation. Cell viability and the cell-cycle distribution were, respectively, analyzed using an MTT assay and flow cytometry. Cell migration was examined using a wound-healing analysis and a transwell assay. Protein expressions and gelatinase activities were, respectively, measured using Western blot and gelatin zymography. Balloon angioplasty-induced neointimal formation was induced in a rat carotid artery model and then examined using immunohistochemical staining. Ugonin J induced cell-cycle arrest at the G 0 /G 1 phase and apoptosis to inhibit VSMC growth. Ugonin J also exhibited marked suppressive activity on VSMC migration. Ugonin J significantly reduced activations of focal adhesion kinase, phosphoinositide 3-kinase, v-akt murine thymoma viral oncogene homolog 1, and extracellular signal-regulated kinase 1/2 proteins. Moreover, ugonin J obviously reduced expressions and activity levels of matrix metalloproteinase-2 and matrix metalloproteinase-9. In vivo data indicated that ugonin J prevented balloon angioplasty-induced neointimal hyperplasia. Our study suggested that ugonin J has the potential for application in the prevention of balloon injury-induced neointimal formation. Copyright © 2017 John Wiley & Sons, Ltd.

INTRODUCTION: Anticipated changes in the global atmospheric water cycle

Science.gov (United States)

Allan, Richard P.; Liepert, Beate G.

2010-06-01

an important example. Understanding surface solar 'dimming' and 'brightening' trends in the context of past and current changes in the water cycle are discussed in a guest editorial by Wild and Liepert (2010). The key roles anthropogenic aerosols can play on a regional scale are discussed by Lau et al (2010) through their study of the regional impact of absorbing aerosols on warming and snow melt over the Himalayas. The overarching goal of climate prediction is to provide reliable, probabilistic estimates of future changes. Relating hydrological responses back to a sound physical basis, the motivation for this special focus issue, is paramount in building confidence in anticipated changes, especially in the global water cycle. We are grateful to the reviewers and the journal editorial board for making this focus issue possible. Focus on Anticipated Changes in the Global Atmospheric Water Cycle Contents Editorials The global atmospheric water cycle Lennart Bengtsson The Earth radiation balance as driver of the global hydrological cycle Martin Wild and Beate Liepert Letters Enhanced surface warming and accelerated snow melt in the Himalayas and Tibetan Plateau induced by absorbing aerosols William K M Lau, Maeng-Ki Kim, Kyu-Myong Kim and Woo-Seop Lee Current changes in tropical precipitation Richard P Allan, Brian J Soden, Viju O John, William Ingram and Peter Good Direct versus indirect effects of tropospheric humidity changes on the hydrologic cycle S C Sherwood How closely do changes in surface and column water vapor follow Clausius-Clapeyron scaling in climate change simulations? P A O'Gorman and C J Muller Linking increases in hourly precipitation extremes to atmospheric temperature and moisture changes Geert Lenderink and Erik van Meijgaard Are climate-related changes to the character of global-mean precipitation predictable? Graeme L Stephens and Yongxiang Hu A comparison of large scale changes in surface humidity over land in observations and CMIP3 general

Alcohol Intake Increases in Adolescent C57BL/6J Mice during Intermittent Cycles of Phase-Delayed, Long-Light Conditions

Directory of Open Access Journals (Sweden)

Joshua J. Gamsby

2017-08-01

Full Text Available Adolescents naturally go to bed and awaken late, but are forced to awaken early for school and work. This leads to “social jetlag”, a state of circadian desynchrony (CD, in which internal biological rhythms are out of sync with behavioral rhythms. CD is associated with increased alcohol intake in adults, but has been less well-studied in adolescents. The goal of this study was to model adolescent alcohol intake during similar CD conditions in male C57BL/6J mice. Free access alcohol intake, water intake and wheel-running activity were measured during a normal 12HR photoperiod or during alternating photoperiod (Experiment 1: 12 h light for 4 days followed by 18 h light for 3 days, with dark (activity onset delayed 9 h during the 18HR photoperiod; Experiment 2: 12 h light for 4 days followed by 6 h light for 3 days, with dark onset delayed 3 h during the 6HR photoperiod. In Experiment 1, CD produced a small but significant increase in the total alcohol intake per day as well as in intake in bouts, with the greatest increase over controls in the hours following the 6HR dark period. Additionally, the pattern of alcohol intake in bouts shifted to increase alcohol intake during the shorter dark period. In Experiment 2, the opposite effect occurred—the longer dark cycle led to lower alcohol drinking in the second half of the dark period. However, in Experiment 2, CD produced no significant changes in either total alcohol intake or alcohol intake in bouts. Conclusion: shifts in the light cycle that disrupt the regular pattern of day and night, and increase the length of the night phase, are sufficient to increase both drinking in bouts and restricted drinking in adolescent mice, modeling increased alcohol intake in adolescents during CD.

7 CFR 58.141 - Alternate quality control program.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by the...

The evolution of the rest-frame J- and H-band luminosity function of galaxies to z=3.5

OpenAIRE

Stefanon, Mauro; Marchesini, Danilo

2011-01-01

We present the rest-frame J- and H-band luminosity function (LF) of field galaxies, based on a deep multi-wavelength composite sample from the MUSYC, FIRES and FIREWORKS survey public catalogues, covering a total area of 450 arcmin^2. The availability of flux measurements in the Spitzer IRAC 3.6, 4.5, 5.8, and 8 um channels allows us to compute absolute magnitudes in the rest-frame J and H bands up to z=3.5 minimizing the dependence on the stellar evolution models. We compute the LF in the fo...

Observation of f sub 1 (1285) yields. pi. sup +. pi. sup -. pi. sup +. pi. sup - in radiative J/. psi. decays

Energy Technology Data Exchange (ETDEWEB)

Bolton, T; Bunnell, K O; Cassell, R E; Coward, D H; Labs, J; Odian, A; Pitman, D; Schindler, R H; Toki, W [Stanford Linear Accelerator Centre, Stanford Univ., CA (United States); Brown, J S; Burnett, T H; Li, A; Mir, R; Mockett, P M; Parrish, L; Willutzki, H J [Dept. of Physics, Univ. Washington, Seattle, WA (United States); Burchell, M; Drinkard, J; Gatto, C; Heusch, C A; Lockman, W S; Sadrozinski, H F.W.; Scarlatella, M; Schalk, T L; Seiden, A; Weinstein, A J; Xu, R [Santa Cruz Inst. for Particle Physics, Univ. California, CA (United States); Coffman, D; DeJongh, F; Dubois, G P; Eigen, G; Hitlin, D G; Matthews, C G; Richman, J D; Wisniewski, W J; Zhu, Y [Dept. of Physics, California Inst. of Tech., Pasadena, CA (United States); Eisenstein, B I; Freese, T; Gladding, G; Izen, J M; Kim, P C; Stockdale, I E; Tripsas, B [Dept. of Physics, Univ. of Illinois at Urbana-Champaign, Urbana, IL (United States); Mallik, U; Wang, M Z [Dept. of; Mark III Collaboration

1992-04-02

We present an analysis of J/{psi}{yields}{gamma}f{sub 1}(1285), f{sub 1}(1285){yields}{pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -}, using the Mark III detector at SPEAR, based on 5.8x10{sup 6} produced J/{psi} events. We measure B(J/{psi}{yields}{gamma}f{sub 1}(1285), f{sub 1}(1285){yields}{pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})=(4.8{+-}1.3{+-}0.9)x10{sup -5}. We obtain a new measurement of the absolute branching ratio of J/{psi}{yields}{gamma}f{sub 1}(1285). The mixing angle of the f{sub 1}(1285) and the f{sub 1}(1420) in the 1{sup ++} nonet is determined. (orig.).

7 CFR 58.142 - Product quality and stability.

Science.gov (United States)

2010-01-01

... production of the highest quality of finished product and improve product stability. Milk should not be more... 7 Agriculture 3 2010-01-01 2010-01-01 false Product quality and stability. 58.142 Section 58.142... Procedures § 58.142 Product quality and stability. The receiving, holding and processing of milk and cream...

7 CFR 58.249 - Instant nonfat dry milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Instant nonfat dry milk. 58.249 Section 58.249... Products Bearing Usda Official Identification § 58.249 Instant nonfat dry milk. (a) Only instant nonfat dry milk manufactured and packaged in accordance with the requirements of this part and with the applicable...

46 CFR 58.30-30 - Fluid power cylinders.

Science.gov (United States)

2010-10-01

... all pneumatic power transmission systems. (b) Fluid power cylinders consisting of a container and a... 46 Shipping 2 2010-10-01 2010-10-01 false Fluid power cylinders. 58.30-30 Section 58.30-30... MACHINERY AND RELATED SYSTEMS Fluid Power and Control Systems § 58.30-30 Fluid power cylinders. (a) The...

7 CFR 58.332 - Segregation of raw material.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Segregation of raw material. 58.332 Section 58.332... Specifications for Dairy Plants Approved for USDA Inspection and Grading Service 1 Operations and Operating Procedures § 58.332 Segregation of raw material. The milk and cream received at the dairy plant shall meet...

10 CFR 602.15 - Indirect cost limitations.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Indirect cost limitations. 602.15 Section 602.15 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.15 Indirect cost limitations. Awards issued under this part for conferences and...

Direct and indirect health and safety impacts of electrical generation options

International Nuclear Information System (INIS)

Habegger, L.J.; Gasper, J.R.; Brown, C.D.

1982-01-01

This report is an analysis of the health and safety risks of seven electrical generation systems, all of which have the potential for commercial availability after the year 2000. The systems are compared on the basis of expected public and occupational deaths and lost workdays associated with average unit generation of 1000 MW(e) per year. The risks and associated uncertainties are estimated for all phases of the energy production cycle, including fuel extraction and processing, on-site construction and system operation and maintenance. Also included are the risks of direct and indirect component manufacture, materials production and energy inputs, all of which are major contributors to the risks of the more capital-intensive solar technologies. The potential significance of major health and safety issues that remain largely unquantifiable are also considered. (author)

46 CFR 58.01-50 - Machinery space, noise.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Machinery space, noise. 58.01-50 Section 58.01-50... MACHINERY AND RELATED SYSTEMS General Requirements § 58.01-50 Machinery space, noise. (a) Each machinery space must be designed to minimize the exposure of personnel to noise in accordance with IMO A.468(XII...

46 CFR 58.50-5 - Gasoline fuel tanks.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Gasoline fuel tanks. 58.50-5 Section 58.50-5 Shipping... AND RELATED SYSTEMS Independent Fuel Tanks § 58.50-5 Gasoline fuel tanks. (a) Construction—(1) Shape...) Installation. (1) Gasoline fuel tanks used for propulsion shall be located in water-tight compartments separate...

7 CFR 58.521 - Pasteurization and product flow.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Pasteurization and product flow. 58.521 Section 58.521... Procedures § 58.521 Pasteurization and product flow. (a) The skim milk used for the manufacture of cottage.... If held more than two hours between pasteurization and time of setting, the skim milk shall be cooled...

Cell cycle perturbations induced by Cisplatin in normal and tumor transformed cells

Czech Academy of Sciences Publication Activity Database

Mareš, Vladislav; Mazzini, G.; Lisá, Věra; Ferrari, C.; Malík, Radek; Šedo, A.

2001-01-01

Roč. 5, - (2001), s. 23-29 ISSN 1212-3137 Grant - others:GA UK(XC) 58/1999/C; LF UK(XC) 206019-2-"Oncology" Institutional research plan: CEZ:AV0Z5011922 Keywords : cell cycle * cisplatin * DNA content Subject RIV: FD - Oncology ; Hematology

Thermodynamic of the associated cycle and application to the assembly of thermochemical iodine sulphur cycle and a nuclear engine for the hydrogen production

International Nuclear Information System (INIS)

Dumont, Y.

2008-01-01

This thesis is devoted to the design of an assembly of a hydrogen production process by the thermochemical iodine-sulphur cycle and a nuclear reactor. The suggested coupling network uses a power cycle which produces a work which is directly used for the heat pump running. The purpose of this thermodynamic cycle association is to recover the rejected energy at low temperature of a process to provide the energy needs of this same process at high temperature. This association is applied to the studied coupling. The construction of the energy distribution network is designed by the pinch analysis. In the case of a conventional coupling, the efficiency of hydrogen production is 22.0%. By integrating the associated cycles into the coupling, the efficiency of production is 42.6%. The exergetic efficiency, representative of the energy using quality, increases from 58.7% to 85.4%. (author) [fr

Comparison of potential radiological impacts of 233U and 239Pu fuel cycles

International Nuclear Information System (INIS)

Meyer, H.R.; Little, C.A.; Witherspoon, J.P.; Till, J.E.

1979-01-01

Nuclear fuel cycles utilizing 233 U are currently the subject of considerable interest in the United States. This paper focuses on the identification of significant differences between the off-site radiological hazards posed by 232 Th/ 233 U (Th/U) and 238 U/ 239 Pu (U/Pu) fuel cycles, and represents a portion of our involvement in the Nonproliferation Alternative Systems Assessment Program (NASAP), to be used in support of the International Fuel Cycle Evaluation (INFCE). The major contributors to radiological dose are likely to be uranium mining and milling (58.5% of total fuel cycle dose), reprocessing (33.9%), and light-water reactor power generation (7.3%). The remainder of the cycle, including enrichment processes, fuel fabrication, transportation, and waste management, contributes only 0.3% to total estimated fuel cycle dose

10 CFR 605.16 - Indirect cost limitations.

Science.gov (United States)

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Indirect cost limitations. 605.16 Section 605.16 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS THE OFFICE OF ENERGY RESEARCH FINANCIAL ASSISTANCE PROGRAM § 605.16 Indirect cost limitations. Awards issued under this part for conferences and scientific...

77 FR 41899 - Indirect Food Additives: Polymers

Science.gov (United States)

2012-07-17

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 177 [Docket No. FDA-2012-F-0031] Indirect Food Additives: Polymers AGENCY: Food and Drug Administration, HHS. ACTION... CFR part 177 is amended as follows: PART 177--INDIRECT FOOD ADDITIVES: POLYMERS 0 1. The authority...

Exergy optimization for a novel combination of organic Rankine cycles, Stirling cycle and direct expander turbines

Science.gov (United States)

Moghimi, Mahdi; Khosravian, Mohammadreza

2018-06-01

In this paper, a novel combination of organic Rankine cycles (ORCs), Stirling cycle and direct expander turbines is modeled and optimized using the genetic algorithm. The Exergy efficiency is considered as an objective function in the genetic algorithm. High efficiency is the main advantage of Stirling cycle, however, it needs nearly isothermal compressor and turbine. Therefore, an argon ORC and a R14 ORC are placed before and after the Striling cycle along with two expander turbines at the end of the line. Each component and cycle of the proposed plant in this article is verified by the previous works available in the literature and good agreement is achieved. The obtained results reveal that 27.98%, 20.86% and 12.90% of the total cold exergy are used by argon ORC, Stirling cycle and R14 ORC, respectively. Therefore, utilization of the Stirling cycle is a good idea for the LNG line cold exergy. The maximum exergy destruction occurs in the heat exchanger after the argon ORC (85.786 kJ/s per one kg/s LNG) due to the wasted cold exergy, which can be used for air conditioning systems in the plant. Finally, it would be shown that the maximum efficiency of the proposed plant is 54.25% and the maximum output power is 355.72 kW.

Exergy optimization for a novel combination of organic Rankine cycles, Stirling cycle and direct expander turbines

Science.gov (United States)

Moghimi, Mahdi; Khosravian, Mohammadreza

2018-01-01

In this paper, a novel combination of organic Rankine cycles (ORCs), Stirling cycle and direct expander turbines is modeled and optimized using the genetic algorithm. The Exergy efficiency is considered as an objective function in the genetic algorithm. High efficiency is the main advantage of Stirling cycle, however, it needs nearly isothermal compressor and turbine. Therefore, an argon ORC and a R14 ORC are placed before and after the Striling cycle along with two expander turbines at the end of the line. Each component and cycle of the proposed plant in this article is verified by the previous works available in the literature and good agreement is achieved. The obtained results reveal that 27.98%, 20.86% and 12.90% of the total cold exergy are used by argon ORC, Stirling cycle and R14 ORC, respectively. Therefore, utilization of the Stirling cycle is a good idea for the LNG line cold exergy. The maximum exergy destruction occurs in the heat exchanger after the argon ORC (85.786 kJ/s per one kg/s LNG) due to the wasted cold exergy, which can be used for air conditioning systems in the plant. Finally, it would be shown that the maximum efficiency of the proposed plant is 54.25% and the maximum output power is 355.72 kW.

7 CFR 58.439 - Cheese from unpasteurized milk.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Cheese from unpasteurized milk. 58.439 Section 58.439... Procedures § 58.439 Cheese from unpasteurized milk. If the cheese is labeled as “heat treated”, “unpasteurized,” “raw milk”, or “for manufacturing” the milk may be raw or heated at temperatures below...

Determination of the magnetocaloric entropy change in the presence of phase separation and metastability: The case of Eu0.58Sr0.42MnO3

International Nuclear Information System (INIS)

Guillou, F.; Hardy, V.; Fruchart, D.; Zawilski, B.

2014-01-01

The magnetocaloric effect (MCE) in the manganite Eu 0.58 Sr 0.42 MnO 3 was derived by different methods, in a field range very sensitive to the phenomenon of phase separation. It turns out that a strong scatter in the MCE features was observed. When the applied field is less than the field required to complete the transition, it is found that the MCE can be strongly overestimated by “standard” indirect measurements. A way to properly estimate the MCE around a first order transition in the presence of phase separation and metastability is proposed. - Highlights: • The entropy change was investigated in an oxide with pronounced metastable effects. • A strong scatter is observed among results derived from several indirect methods. • It is found that even the calorimetric approach can be proned to artefacts. • A method is proposed to evaluate a “real” magnetocaloric entropy change

Indirect inference with time series observed with error

DEFF Research Database (Denmark)

Rossi, Eduardo; Santucci de Magistris, Paolo

estimation. We propose to solve this inconsistency by jointly estimating the nuisance and the structural parameters. Under standard assumptions, this estimator is consistent and asymptotically normal. A condition for the identification of ARMA plus noise is obtained. The proposed methodology is used......We analyze the properties of the indirect inference estimator when the observed series are contaminated by measurement error. We show that the indirect inference estimates are asymptotically biased when the nuisance parameters of the measurement error distribution are neglected in the indirect...... to estimate the parameters of continuous-time stochastic volatility models with auxiliary specifications based on realized volatility measures. Monte Carlo simulations shows the bias reduction of the indirect estimates obtained when the microstructure noise is explicitly modeled. Finally, an empirical...

THE IMPORTANCE OF THE ERYTHROCYTES OSMOTIC FRAGILITY TEST PERFORMED IN CHILDREN WITH INDIRECT HYPERBILIRUB1NEMIA

Directory of Open Access Journals (Sweden)

Ivana Stojanović

2005-07-01

Full Text Available The osmotic fragility test of erythrocytes is useful in the diagnosis of different types of hereditary hemolytic anemias followed with hyperbilirubinemia. Hemolytic anemias, characterized by accelerated destruction of red blood cells, are usually the consequence of many metabolic abnormalities like cellular membrane defect, erythrocyte enzymes defect or hemoglobin abnormalities – hemoglobinopathies. The object of our study was to assess the relationship between osmotic fragility test of erythrocytes and severity of indirect hyperbilirubinemia in some inherited erythrocytes’ disorders. We did the osmotic fragility test of erythrocytes by using Dacie, s method with normal values of erythrocytes hemolysis between 0,48 to 0,34% NaCl (minimal to maximal hemolysis. In hereditary spherocytosis, fragility of erythrocytes was increased (min. at 0,50 % NaCl to max. 0,44 % NaCl . In the child with β- thalassemia and cycle cell anemia erythrocytes fragility was decreased (min . at 0,42 to max. 0,32 % NaCl, that is 0,40% min. of hemolysis and 0,34% max. hemolysis in the second case. In newborn infants with high levels of indirect bilirubin in serum as a cause of physiological jaundice, the osmotic fragility test was within a normal range. Our findings point out the diagnostic value of osmotic fragility test in assessing patients with the indirect hyperbilirubinemia. This simple and important diagnostic test can be performed in small laboratories.

Calibrated delivery drape versus indirect gravimetric technique for the measurement of blood loss after delivery: a randomized trial.

Science.gov (United States)

Ambardekar, Shubha; Shochet, Tara; Bracken, Hillary; Coyaji, Kurus; Winikoff, Beverly

2014-08-15

Trials of interventions for PPH prevention and treatment rely on different measurement methods for the quantification of blood loss and identification of PPH. This study's objective was to compare measures of blood loss obtained from two different measurement protocols frequently used in studies. Nine hundred women presenting for vaginal delivery were randomized to a direct method (a calibrated delivery drape) or an indirect method (a shallow bedpan placed below the buttocks and weighing the collected blood and blood-soaked gauze/pads). Blood loss was measured from immediately after delivery for at least one hour or until active bleeding stopped. Significantly greater mean blood loss was recorded by the direct than by the indirect measurement technique (253.9 mL and 195.3 mL, respectively; difference = 58.6 mL (95% CI: 31-86); p 500 mL (8.7% vs. 4.7%, p = 0.02). The study suggests a real and significant difference in blood loss measurement between these methods. Research using blood loss measurement as an endpoint needs to be interpreted taking measurement technique into consideration. This study has been registered at clinicaltrials.gov as NCT01885845.

Moonstruck how lunar cycles affect life

CERN Document Server

Naylor, Ernest

2015-01-01

Throughout history, the influence of the full Moon on humans and animals has featured in folklore and myths. Yet it has become increasingly apparent that many organisms really are influenced indirectly, and in some cases directly, by the lunar cycle. Breeding behaviour among some marine animals has been demonstrated to be controlled by internal circalunar biological clocks, to the point where lunar-daily and lunar-monthly patterns of Moon-generated tides are embedded in their genes. Yet, intriguingly, Moon-related behaviours are also found in dry land and fresh water species living far beyond the influence of any tides. In Moonstruck, Ernest Naylor dismisses the myths concerning the influence of the Moon, but shows through a range of fascinating examples the remarkable real effects that we are now finding through science. He suggests that since the advent of evolution on Earth, which occurred shortly after the formation of the Moon, animals evolved adaptations to the lunar cycle, and considers whether, if Moo...

7 CFR 58.637 - Cooling the mix.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Cooling the mix. 58.637 Section 58.637 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE...

7 CFR 58.638 - Freezing the mix.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Freezing the mix. 58.638 Section 58.638 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE...

7 CFR 58.619 - Mix processing room.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Mix processing room. 58.619 Section 58.619 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE...

Identification and characterization of a DnaJ gene from red alga Pyropia yezoensis (Bangiales, Rhodophyta)

Science.gov (United States)

Liu, Jiao; Li, Xianchao; Tang, Xuexi; Zhou, Bin

2016-03-01

Members of the DnaJ family are proteins that play a pivotal role in various cellular processes, such as protein folding, protein transport and cellular responses to stress. In the present study, we identified and characterized the full-length DnaJ cDNA sequence from expressed sequence tags of Pyropia yezoensis ( PyDnaJ) via rapid identification of cDNA ends. This cDNA encoded a protein of 429 amino acids, which shared high sequence similarity with other identified DnaJ proteins, such as a heat shock protein 40/DnaJ from Pyropia haitanensis. The relative mRNA expression level of PyDnaJ was investigated using real-time PCR to determine its specific expression during the algal life cycle and during desiccation. The relative mRNA expression level in sporophytes was higher than that in gametophytes and significantly increased during the whole desiccation process. These results indicate that PyDnaJ is an authentic member of the DnaJ family in plants and red algae and might play a pivotal role in mitigating damage to P. yezoensis during desiccation.

Impacts of Human Alteration of the Nitrogen Cycle in the U.S. on Radiative Forcing

Science.gov (United States)

Nitrogen cycling processes affect radiative forcing directly through emissions of nitrous oxide (N2O) and indirectly because emissions of nitrogen oxide (NO x ) and ammonia (NH3) affect atmospheric concentrations of methane (CH4), carbon dioxide (CO2), water vapor (H2O), ozone (O...

A novel Geobacteraceae-specific outer membrane protein J (OmpJ is essential for electron transport to Fe (III and Mn (IV oxides in Geobacter sulfurreducens

Directory of Open Access Journals (Sweden)

Schiffer Marianne

2005-07-01

reduction. Conclusion OmpJ is a putative porin found in the outer membrane of the model metal reducer G. sulfurreducens that is required for respiration of extracellular electron acceptors such as soluble and insoluble metals. The effect of OmpJ in extracellular electron transfer is indirect, as OmpJ is required to keep the integrity of the periplasmic space necessary for proper folding and functioning of periplasmic and outer membrane electron transport components. The exclusive presence of ompJ in members of the Geobacteraceae family as well as its role in metal reduction suggest that the ompJ sequence may be useful in tracking the growth or activity of Geobacteraceae in sedimentary environments.

Direct and indirect methods for the determination of vitamin K3 using differential pulse polarography and application to pharmaceuticals.

Science.gov (United States)

Somer, Güler; Doğan, Mehmet

2008-11-01

Two methods for the determination of vitamin K(3) have been developed. Vitamin K(3) in its oxidized form is determined by direct and indirect methods. Its standard solution was prepared by the indirect method using Ti(III) as reducing agent. For this purpose vitamin K(3) (menadion) in a clinical injection solution, which is in its hydroquinone form in the presence of sulfite, is oxidized with oxygen. In 0.2 M HAc and 0.02 M HCl electrolyte vitamin K(3) and Ti(IV) have reduction peaks at -0.58 V at -0.82 V respectively. The reaction between Ti(III) and vitamin takes place quantitatively in a medium of 0.2 M HAc and 0.002 M HCl. After the reduction, the reaction product Ti(IV) is followed from its polarographic peak at about -0.82 V. The most important result in this work is that, with this method vitamin K(3) can be standardized and after standardization this solution can be used for the direct determination in routine analysis with a very simple and fast method, using only the peak at -0.71 V in 0.2 M HAc medium. Both direct and indirect methods have been used for the determination of Vitamin K(3) in a clinical injection solution. The limit of quantification (LOQ) was 1.5x10(-6) M and in both methods the detection limit found was 7x10(-7) M.

Indirect techniques in nuclear astrophysics

International Nuclear Information System (INIS)

Mukhamedzhanov, A.M.; Tribble, R.E.; Blokhintsev, L.D.; Cherubini, S.; Spitaleri, C.; Kroha, V.; Nunes, F.M.

2005-01-01

It is very difficult or often impossible to measure in the lab conditions nuclear cross sections at astrophysically relevant energies. That is why different indirect techniques are used to extract astrophysical information. In this talk different experimental possibilities to get astrophysical information using radioactive and stable beams will be addressed. 1. The asymptotic normalization coefficient (ANC) method. 2. Radiative neutron captures are determined by the spectroscopic factors (SP). A new experimental technique to determine the neutron SPs will be addressed. 3. 'Trojan Horse' is another unique indirect method, which allows one to extract the astrophysical factors for direct and resonant nuclear reactions at astrophysically relevant energies. (author)

7 CFR 58.647 - Composition requirements for ice cream.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Composition requirements for ice cream. 58.647 Section 58.647 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... requirements for ice cream. See § 58.605(a). ...

Indirect Taxes in Romania – an Econometric Analysis

Directory of Open Access Journals (Sweden)

Daniela Penu

2016-03-01

Full Text Available Indirect taxes have a significant weight in the GDP. Statistical data reveals that the new states that joined the EU in its funding sources to the greatest extent through indirect taxes. They reveal, on the one hand, reducing the tax burden on the producer, and on the other hand, the difficulty faced by the country in direct tax collection, but also some problems of social nature. This article proposes an econometric analysis of the relationship between indirect taxes and household final consumption expenditure.

Activity cycles in members of young loose stellar associations

Science.gov (United States)

Distefano, E.; Lanzafame, A. C.; Lanza, A. F.; Messina, S.; Spada, F.

2017-10-01

-correlated with the effective temperature Teff, the photometric shear ΔΩphot and the radius RC at which the convective zone is located. We investigated how Pcyc and ⟨ IQR ⟩ evolve with the stellar age. We found that Pcyc is about constant and that ⟨ IQR ⟩ decreases with the stellare age in the range 4-95 Myr. Finally we investigated the magnetic activity of the star AB Dor A by merging All Sky Automatic Survey (ASAS) time series with previous long-term photometric data. We estimated the length of the AB Dor A primary cycle as Pcyc = 16.78 ± 2 yr and we also found shorter secondary cycles with lengths of 400 d, 190 d, and 90 d, respectively. Tables 2 and 3 and Time series are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/606/A58

The nuclear fuel cycle

International Nuclear Information System (INIS)

1998-05-01

After a short introduction about nuclear power in the world, fission physics and the French nuclear power plants, this brochure describes in a digest way the different steps of the nuclear fuel cycle: uranium prospecting, mining activity, processing of uranium ores and production of uranium concentrates (yellow cake), uranium chemistry (conversion of the yellow cake into uranium hexafluoride), fabrication of nuclear fuels, use of fuels, reprocessing of spent fuels (uranium, plutonium and fission products), recycling of energetic materials, and storage of radioactive wastes. (J.S.)

ALMA observations of molecular absorption in four directions toward the Galactic bulge

Science.gov (United States)

Liszt, H.; Gerin, M.

2018-02-01

Context. Alma Cycle 3 observations serendipitously showed strong absorption from diffuse molecular gas in the Galactic bulge at -200 km s-1 51(3σ) for the bulge gas toward J1744 and 58 ± 9 and 64 ± 4 for the disk gas toward J1717 and J1744, respectively, all well above the value of 20-25 typical of the central molecular zone. Conclusions: The kinematics and chemistry of the bulge gas observed toward J1744 more nearly resemble that of gas in the Milky Way disk than in the central molecular zone.

Studies on capillary tube expansion device used in J-T refrigerators operating with nitrogen-hydrocarbon mixtures

Science.gov (United States)

Harish Kruthiventi, S. S.; Venkatarathnam, G.

2017-10-01

Capillary tube expansion devices are used extensively in small closed cycle J-T refrigerators operating with refrigerant mixtures due to its low cost and the absence of any moving parts. It is possible for J-T refrigerators operating with mixtures that the velocity of refrigerant mixture at capillary tube outlet reaches a value where it equals the speed of sound at certain conditions. The variation of the speed of sound of nitrogen-hydrocarbon mixtures used in J-T refrigerators has been studied in two phase (vapour-liquid) and three-phase (Vapour-liquid-liquid) region as a function of temperature and pressure in this work. Also the conditions under which choking occurs in practical J-T refrigerators is investigated.

High energy multi-cycle terahertz generation

International Nuclear Information System (INIS)

Ahr, Frederike Beate

2017-10-01

Development of compact electron accelerators and free-electron lasers requires novel acceleration schemes at shorter driving wavelengths. The Axsis project seeks to develop terahertz based electron acceleration as well as the high energy terahertz sources required. This thesis explores the methods and optical material required for the generation of highenergy multi-cycle terahertz pulses. Two experimental concepts to generate high energy terahertz radiation are presented. In addition the theoretical background and the optical properties of pertinent optical materials in the terahertz range are discussed. Investigations of the materials are performed with a terahertz time domain spectrometer and a Fourier transform infrared spectrometer. The nonlinear optical crystal lithium niobate as well as other crystals suitable for the terahertz generation and in addition polymers and other radiation attenuators are characterized in the range from 0.2 to 1 THz. The theory describing the generation of narrowband terahertz radiation is evaluated. The experimental setups to generate terahertz radiation and to characterize its properties are described. The specific crystals - periodically poled lithium niobate (PPLN) - used in the experiments to generate the multi-cycle terahertz radiation are examined to determine e.g. the poling period. The first experimental concept splits the ultra fast, broadband pump pulses into a pulse train in order to pump the PPLN at a higher fluence while increasing the damage limit. The measurements confirm that a pulse train of ultra short, broadband pump pulses increases not only the terahertz energy but also the energy conversion efficiency. The second experimental concept utilizes chirped and delayed infrared laser pulses. This pulse format makes it possible to pump the crystal with high energy pulses resulting in high energy terahertz radiation. The concept is optimized to reach energies up to 127 μJ exceeding the existing results of narrowband

High energy multi-cycle terahertz generation

Energy Technology Data Exchange (ETDEWEB)

Ahr, Frederike Beate

2017-10-15

Development of compact electron accelerators and free-electron lasers requires novel acceleration schemes at shorter driving wavelengths. The Axsis project seeks to develop terahertz based electron acceleration as well as the high energy terahertz sources required. This thesis explores the methods and optical material required for the generation of highenergy multi-cycle terahertz pulses. Two experimental concepts to generate high energy terahertz radiation are presented. In addition the theoretical background and the optical properties of pertinent optical materials in the terahertz range are discussed. Investigations of the materials are performed with a terahertz time domain spectrometer and a Fourier transform infrared spectrometer. The nonlinear optical crystal lithium niobate as well as other crystals suitable for the terahertz generation and in addition polymers and other radiation attenuators are characterized in the range from 0.2 to 1 THz. The theory describing the generation of narrowband terahertz radiation is evaluated. The experimental setups to generate terahertz radiation and to characterize its properties are described. The specific crystals - periodically poled lithium niobate (PPLN) - used in the experiments to generate the multi-cycle terahertz radiation are examined to determine e.g. the poling period. The first experimental concept splits the ultra fast, broadband pump pulses into a pulse train in order to pump the PPLN at a higher fluence while increasing the damage limit. The measurements confirm that a pulse train of ultra short, broadband pump pulses increases not only the terahertz energy but also the energy conversion efficiency. The second experimental concept utilizes chirped and delayed infrared laser pulses. This pulse format makes it possible to pump the crystal with high energy pulses resulting in high energy terahertz radiation. The concept is optimized to reach energies up to 127 μJ exceeding the existing results of narrowband

Aerosol indirect effects on summer precipitation in a regional climate model for the Euro-Mediterranean region

Science.gov (United States)

Da Silva, Nicolas; Mailler, Sylvain; Drobinski, Philippe

2018-03-01

Aerosols affect atmospheric dynamics through their direct and semi-direct effects as well as through their effects on cloud microphysics (indirect effects). The present study investigates the indirect effects of aerosols on summer precipitation in the Euro-Mediterranean region, which is located at the crossroads of air masses carrying both natural and anthropogenic aerosols. While it is difficult to disentangle the indirect effects of aerosols from the direct and semi-direct effects in reality, a numerical sensitivity experiment is carried out using the Weather Research and Forecasting (WRF) model, which allows us to isolate indirect effects, all other effects being equal. The Mediterranean hydrological cycle has often been studied using regional climate model (RCM) simulations with parameterized convection, which is the approach we adopt in the present study. For this purpose, the Thompson aerosol-aware microphysics scheme is used in a pair of simulations run at 50 km resolution with extremely high and low aerosol concentrations. An additional pair of simulations has been performed at a convection-permitting resolution (3.3 km) to examine these effects without the use of parameterized convection. While the reduced radiative flux due to the direct effects of the aerosols is already known to reduce precipitation amounts, there is still no general agreement on the sign and magnitude of the aerosol indirect forcing effect on precipitation, with various processes competing with each other. Although some processes tend to enhance precipitation amounts, some others tend to reduce them. In these simulations, increased aerosol loads lead to weaker precipitation in the parameterized (low-resolution) configuration. The fact that a similar result is obtained for a selected area in the convection-permitting (high-resolution) configuration allows for physical interpretations. By examining the key variables in the model outputs, we propose a causal chain that links the aerosol

The power of indirect social ties

OpenAIRE

Zuo, Xiang; Blackburn, Jeremy; Kourtellis, Nicolas; Skvoretz, John; Iamnitchi, Adriana

2014-01-01

While direct social ties have been intensely studied in the context of computer-mediated social networks, indirect ties (e.g., friends of friends) have seen little attention. Yet in real life, we often rely on friends of our friends for recommendations (of good doctors, good schools, or good babysitters), for introduction to a new job opportunity, and for many other occasional needs. In this work we attempt to 1) quantify the strength of indirect social ties, 2) validate it, and 3) empiricall...

Two distinct neural mechanisms underlying indirect reciprocity.

Science.gov (United States)

Watanabe, Takamitsu; Takezawa, Masanori; Nakawake, Yo; Kunimatsu, Akira; Yamasue, Hidenori; Nakamura, Mitsuhiro; Miyashita, Yasushi; Masuda, Naoki

2014-03-18

Cooperation is a hallmark of human society. Humans often cooperate with strangers even if they will not meet each other again. This so-called indirect reciprocity enables large-scale cooperation among nonkin and can occur based on a reputation mechanism or as a succession of pay-it-forward behavior. Here, we provide the functional and anatomical neural evidence for two distinct mechanisms governing the two types of indirect reciprocity. Cooperation occurring as reputation-based reciprocity specifically recruited the precuneus, a region associated with self-centered cognition. During such cooperative behavior, the precuneus was functionally connected with the caudate, a region linking rewards to behavior. Furthermore, the precuneus of a cooperative subject had a strong resting-state functional connectivity (rsFC) with the caudate and a large gray matter volume. In contrast, pay-it-forward reciprocity recruited the anterior insula (AI), a brain region associated with affective empathy. The AI was functionally connected with the caudate during cooperation occurring as pay-it-forward reciprocity, and its gray matter volume and rsFC with the caudate predicted the tendency of such cooperation. The revealed difference is consistent with the existing results of evolutionary game theory: although reputation-based indirect reciprocity robustly evolves as a self-interested behavior in theory, pay-it-forward indirect reciprocity does not on its own. The present study provides neural mechanisms underlying indirect reciprocity and suggests that pay-it-forward reciprocity may not occur as myopic profit maximization but elicit emotional rewards.

Indirect effects in community ecology: Their definition, study and importance.

Science.gov (United States)

Strauss, S Y

1991-07-01

The diversity of indirect interactions that can occur within communities is large. Recent research on indirect interactions is scattered in the literature under numerous labels. The definition of indirect effects is an important aspect of their study, and clarifies some of the subtle differences among indirect effects found in natural communities. Choosing which species to study, how to manipulate species and for what duration, which attributes to measure and, finally, which analytical techniques to use are all problems facing the community ecologist. Ultimately, we are striving for the best means of determining the relative importance of direct and indirect effects in structuring communities. Copyright © 1991. Published by Elsevier Ltd.

Preschool children's behavioral tendency toward social indirect reciprocity.

Directory of Open Access Journals (Sweden)

Mayuko Kato-Shimizu

Full Text Available Social indirect reciprocity seems to be crucial in enabling large-scale cooperative networks among genetically unrelated individuals in humans. However, there are relatively few studies on social indirect reciprocity in children compared to adults. Investigating whether young children have a behavioral tendency toward social indirect reciprocity will help us understand how and when the fundamental ability to form cooperative relationships among adults is acquired. Using naturalistic observation at a nursery school, this study examined whether 5- to 6-year-olds show a behavioral tendency to engage in social indirect reciprocity in response to their peers' prosocial behavior toward a third party. The results revealed that bystander children tended to display prosocial behavior toward their peers more frequently after observing these peers' prosocial behavior toward third-party peers, compared with control situations; this suggests that 5- to 6-year-olds may have an essential behavioral tendency to establish social indirect reciprocity when interacting with peers in their daily lives. In addition, bystanders tended to display affiliative behavior after observing focal children's prosocial behavior. In other words, observing peers' prosocial behavior toward third-party peers evoked bystanders' positive emotions toward the helpers. Considering both the present results and previous findings, we speculate that in preschoolers, such positive emotions might mediate the increase in the bystander's prosocial behavior toward the helper. In addition, an intuitional emotional process plays an important role in the preschooler's behavioral tendency toward social indirect reciprocity in natural interactions with peers.

Preschool children's behavioral tendency toward social indirect reciprocity.

Science.gov (United States)

Kato-Shimizu, Mayuko; Onishi, Kenji; Kanazawa, Tadahiro; Hinobayashi, Toshihiko

2013-01-01

Social indirect reciprocity seems to be crucial in enabling large-scale cooperative networks among genetically unrelated individuals in humans. However, there are relatively few studies on social indirect reciprocity in children compared to adults. Investigating whether young children have a behavioral tendency toward social indirect reciprocity will help us understand how and when the fundamental ability to form cooperative relationships among adults is acquired. Using naturalistic observation at a nursery school, this study examined whether 5- to 6-year-olds show a behavioral tendency to engage in social indirect reciprocity in response to their peers' prosocial behavior toward a third party. The results revealed that bystander children tended to display prosocial behavior toward their peers more frequently after observing these peers' prosocial behavior toward third-party peers, compared with control situations; this suggests that 5- to 6-year-olds may have an essential behavioral tendency to establish social indirect reciprocity when interacting with peers in their daily lives. In addition, bystanders tended to display affiliative behavior after observing focal children's prosocial behavior. In other words, observing peers' prosocial behavior toward third-party peers evoked bystanders' positive emotions toward the helpers. Considering both the present results and previous findings, we speculate that in preschoolers, such positive emotions might mediate the increase in the bystander's prosocial behavior toward the helper. In addition, an intuitional emotional process plays an important role in the preschooler's behavioral tendency toward social indirect reciprocity in natural interactions with peers.

Comparison of Direct and Indirect Methods of Teaching Breast Self-Examination – Influence on Knowledge and Attitudes of Iranian Nursing and Midwifery Personnel

Science.gov (United States)

Shahbazi, Sara; Heidari, Mohammad; Ghafourifard, Mansour

2017-04-01

Background: Breast cancer is the most common cancer in women. Monthly breast self-examination (BSE) has been presented as one of the best screening methods available. The aim of this study was to compare effects of both direct and indirect methods of teaching of BSE on knowledge and attitudes of nursing and midwifery personnel. Materials and Methods: The present study was performed on 89 nursing and midwifery personnel in Valiasr hospital of Borujen city. Participants were randomly divided into a direct and an indirect training group. Researcher-designed BSE knowledge and attitude and demographic information questionnaires were used for data collection. Results: Before the education intervention, the mean levels of knowledge and attitude were 9.82±2.79 and 56.5±6.21 in the direct training group and 9.59±2.71 and 54.5±4.51 in the indirect training group; after the intervention, they reached 19.2±0.96 and 62.9±4.21, and 11.0±2.58 and 59.0±3.44, respectively. The difference in the mean levels of knowledge and attitude were significantly higher in the direct training group post intervention (Pdirect training methods. Creative Commons Attribution License

38 CFR 18b.58 - Cross-examination.

Science.gov (United States)

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Cross-examination. 18b.58... Procedures § 18b.58 Cross-examination. A witness may be cross-examined on any matter material to the proceeding without regard to the scope of his direct examination. ...

21 CFR 58.31 - Testing facility management.

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2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Testing facility management. 58.31 Section 58.31... management. For each nonclinical laboratory study, testing facility management shall: (a) Designate a study... appropriately tested for identity, strength, purity, stability, and uniformity, as applicable. (e) Assure that...

50 CFR 260.58 - Accessibility for sampling.

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2010-10-01

... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Accessibility for sampling. 260.58 Section... Fishery Products for Human Consumption Sampling § 260.58 Accessibility for sampling. Each applicant shall cause the processed products for which inspection is requested to be made accessible for proper sampling...

7 CFR 58.805 - Meaning of words.

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2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.805 Section 58.805 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... of words. For the purpose of the regulations in this subpart, words in the singular form shall be...

7 CFR 58.1 - Meaning of words.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.1 Section 58.1 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Meaning of words. For the purpose of the regulations in this subpart, words in the singular form shall be...

7 CFR 58.305 - Meaning of words.

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2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.305 Section 58.305 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... words. For the purpose of the regulations in this subpart, words in the singular form shall be deemed to...

7 CFR 58.101 - Meaning of words.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Meaning of words. 58.101 Section 58.101 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... of words. For the purpose of the regulations of this subpart, words in the singular form shall be...

7 CFR 58.6 - Supervision of service.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Supervision of service. 58.6 Section 58.6 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND...

Separating astrophysical sources from indirect dark matter signals

Science.gov (United States)

Siegal-Gaskins, Jennifer M.

2015-01-01

Indirect searches for products of dark matter annihilation and decay face the challenge of identifying an uncertain and subdominant signal in the presence of uncertain backgrounds. Two valuable approaches to this problem are (i) using analysis methods which take advantage of different features in the energy spectrum and angular distribution of the signal and backgrounds and (ii) more accurately characterizing backgrounds, which allows for more robust identification of possible signals. These two approaches are complementary and can be significantly strengthened when used together. I review the status of indirect searches with gamma rays using two promising targets, the Inner Galaxy and the isotropic gamma-ray background. For both targets, uncertainties in the properties of backgrounds are a major limitation to the sensitivity of indirect searches. I then highlight approaches which can enhance the sensitivity of indirect searches using these targets. PMID:25304638

Equation of State Selection for Organic Rankine Cycle Modeling Under Uncertainty

DEFF Research Database (Denmark)

Frutiger, Jerome; O'Connell, John; Abildskov, Jens

In recent years there has been a great interest in the design and selection of working fluids for low-temperature Organic Rankine Cycles (ORC), to efficiently produce electrical power from waste heat from chemical engineering applications, as well as from renewable energy sources such as biomass...... cycle, all influence the model output uncertainty. The procedure is highlighted for an ORC for with a low-temperature heat source from exhaust gas from a marine diesel engine.[1] Saleh B, Koglbauer G, Wendland M, Fischer J. Working fluids for lowtemperature organic Rankine cycles. Energy 2007...

Anti-tumor necrosis factor (TNF drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis

Directory of Open Access Journals (Sweden)

Thorlund K

2012-12-01

Full Text Available Kristian Thorlund,1 Eric Druyts,2 J Antonio Aviña-Zubieta,3,4 Edward J Mills1,21Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada; 2Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada; 3Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; 4Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, CanadaObjective: To evaluate the comparative effectiveness of available tumor necrosis factor-a inhibitors (anti-TNFs for the management of psoriatic arthritis (PsA in patients with an inadequate response to disease-modifying antirheumatic drugs (DMARDs.Methods: We used an exhaustive search strategy covering randomized clinical trials, systematic reviews and health technology assessments (HTA published on anti-TNFs for PsA. We performed indirect comparisons of the available anti-TNFs (adalimumab, etanercept, golimumab, and infliximab measuring relative risks (RR for the psoriatic arthritis response criteria (PsARC, mean differences (MDs for improvements from baseline for the Health Assessment Questionnaire (HAQ by PsARC responders and non-responders, and MD for the improvements from baseline for the psoriasis area and severity index (PASI. When the reporting of data on intervention group response rates and improvements were incomplete, we used straightforward conversions based on the available data.Results: We retrieved data from 20 publications representing seven trials, as well as two HTAs. All anti-TNFs were significantly better than control, but the indirect comparison did not reveal any statistically significant difference between the anti-TNFs. For PsARC response, golimumab yielded the highest RR and etanercept the second highest; adalimumab and infliximab both yielded notably smaller RRs. For HAQ improvement, etanercept and infliximab yielded the largest MD among PsARC responders

Influences of the Landscape on Life Cycle Carbon Intensity of Biofuels

Science.gov (United States)

Adler, P. R.; Del Grosso, S.; Parton, W. J.; Spatari, S.

2011-12-01

Biofuels derived from first (sugar and starch based) and second (lignocellulosic) generation agricultural feedstocks will continue to expand into the market between now and 2022 as incentivized through the federal Energy Independence and Security Act (EISA). Nitrogen use is one of the key environmental concerns within the life cycle since it is both the dominant source of life cycle greenhouse gas (GHG) emissions (energy from N fertilizer production and N2O emissions) and poses risks of reactive N movement throughout agricultural landscapes and watersheds. The other dominant components of the feedstock production on life cycle GHG emissions are tillage and land use change impacts on soil organic carbon (SOC). Opportunities to reduce reactive N through winter double crops may satisfy the dual goal of mitigating N2O emissions and reducing NO3 loses while meeting the objectives of EISA. However, changes in N2O, NO3, and SOC are variable within the agricultural landscape due to soil texture, climate, and crop rotation history thereby increasing the complexity of developing mitigation recommendations. Moreover, the inherent variability in N2O emissions makes it difficult to develop single life cycle carbon intensity profiles for specific fuel pathways that apply across the US, since those pathways will have geographic dependencies. Estimating the expected changes in N2O and SOC is an integral part of quantifying the life cycle GHG profile of biofuels derived from winter double crop feedstocks, while NO3 losses affect both indirect N2O emissions and water quality. The biogeochemical model DayCent was used to simulate the impact of growing winter barley as a double crop following corn before soybean establishment during the winter fallow period for six states in the Mid Atlantic region of the Eastern US on SOC and direct and indirect N2O. EPA is currently reviewing the addition of an advanced fuel pathway for winter barley in the Mid Atlantic region as part of the RFS2

33 CFR 401.58 - Pleasure craft scheduling.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Pleasure craft scheduling. 401.58... OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.58 Pleasure craft scheduling. (a) The transit of pleasure craft shall be scheduled by the traffic controller or the officer in...

40 CFR 52.58 - Control strategy: Lead.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Control strategy: Lead. 52.58 Section...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.58 Control strategy: Lead. The lead plan... the lead standard throughout Alabama. The lead plan submitted by the State on October 7, 1985, and...

Active transfer of poloidal magnetic energy during plasma disruptions in J-TEXT

International Nuclear Information System (INIS)

Zhang, Ming; Zhang, Jun; Rao, Bo; Chen, Zhongyong; Li, Xiaolong; Xu, Wendi; Pan, Yuan; Yu, Kexun

2016-01-01

Highlights: • An alternative plasma disruption mitigation method by transferring partial poloidal magnetic energy out of the vacuum vessel has been presented in this paper. • This method can reduced the magnetic energy dissipated inside the vacuum vessel during disruption and mitigated the disruption damage. • This method has been experimentally verified in J-TEXT with an experiment system set up. • According to the experimental results, the magnetic energy dissipated inside the vacuum vessel during disruption can be reduced by 20% or more and the loop voltage can be reduced by 58%. - Abstract: The magnitude of the damaging effects of plasma disruptions on vacuum vessel (VV) components increases with the thermal energy and poloidal magnetic energy dissipated inside the VV. This study focuses on an alternative method, by which partial poloidal magnetic energy is transferred out of the VV. The quantity of the poloidal magnetic energy dissipated inside the VV (W_d_i_s) can be reduced with this method, and the damaging effects can be mitigated. Partial magnetic energy is transferred based on magnetic coupling by a group of energy transfer coils (ETCs) that are coupled with the plasma current. This method, which is called magnetic energy transfer (MET), has been experimentally verified in J-TEXT. W_d_i_s can be reduced by approximately 20%, and the loop voltage can be reduced by 58%. MET is established as a novel, promising, and effective plasma disruption mitigation method.

Indirect search for dark matter with AMS

International Nuclear Information System (INIS)

Goy, Corinne

2006-01-01

This document summarises the potential of AMS in the indirect search for Dark Matter. Observations and cosmology indicate that the Universe may include a large amount of Dark Matter of unknown nature. A good candidate is the Ligthest Supersymmetric Particle in R-Parity conserving models. AMS offers a unique opportunity to study Dark Matter indirect signature in three spectra: gamma, antiprotons and positrons

A review of Indirect Matrix Converter Topologies

Directory of Open Access Journals (Sweden)

Salem Rahmani

2015-08-01

Full Text Available Abstract—Matrix Converter (MC is a modern direct AC/AC electrical power converter without dc-link capacitor. MC is operated in four quadrant, assuring a control of the output voltage, amplitude and frequency. The matrix converter has recently attracted significant attention among researchers and it has become increasing attractive for applications of wind energy conversion, military power supplies, induction motor drives, etc. Recently, different MC topologies have been proposed and developed which have their own advantages and disadvantages. Matrix converter can be classified as direct and indirect structures. The direct one has been elaborated in previous work. In this paper the indirect MCs are reviewed. Different characteristics of the indirect MC topologies are mentioned to show the strengths and weaknesses of such converter topologies.

24 CFR 58.22 - Limitations on activities pending clearance.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Limitations on activities pending clearance. 58.22 Section 58.22 Housing and Urban Development Office of the Secretary, Department of Housing... RESPONSIBILITIES General Policy: Environmental Review Procedures § 58.22 Limitations on activities pending...

19 CFR 210.58 - Provisional acceptance of the motion.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Provisional acceptance of the motion. 210.58 Section 210.58 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Temporary Relief § 210.58 Provisional acceptance of...

SVX Sequence Crate Custom J2/J3 Backplane

International Nuclear Information System (INIS)

Utes, M.

1997-01-01

The Custom J2/J3 Backplane is a full length (21 slot) user specified custom 3U backplane to be used in both the J2 and J3 positions. Slot spacing is identical to that used for VME (0.8-inch), and each backplane shall fit into a standard Eurocard VME style crate. The purpose of the Custom J2/J3 Backplane is to send and receive control and clock signals from the SVX chips via 3M pleated foil cables (Slots 2-21), and in slot 1, accept a cable connector and route its signal through to a signal distribution board.

58 . ORIGINAL ARTICLE

African Journals Online (AJOL)

Dr Oboro VO

Key words: Multidrug resistant, blood culture, typhoid fever. ... health menace especially in developing countries. It is .... Southeast Asian J Trop ... Evaluation and comparison of different blood ... European Journal of Clinical Microbiology.

Indirect Control for Demand Side Management – A Conceptual Introduction

DEFF Research Database (Denmark)

Heussen, Kai; You, Shi; Biegel, Benjamin

2012-01-01

The concept of “indirect control” has become a relevant discussion term in relation to activation distributed and small-scale demand and generation units to provide resources for power system balancing. The term and its association with price signals has, however caused some confusion as to its...... correct definition, either as a control or a market concept. This paper aims to provide a conceptual introduction to "indirect control" for management of small and distributed demand side resources. A review of control concepts and an analysis of "indirectness" features are provided to create a framework...... for systematic classification of indirect control strategies. The concepts developed then enable a discussion of control performance and valuation of direct- and indirect control strategies....

Feedback of global warming to soil carbon cycling in forest ecosystems

International Nuclear Information System (INIS)

Nakane, Kaneyuki

1993-01-01

Thus in this study the simulation of soil carbon cycling and dynamics of its storage in several types of mature forests developed from the cool-temperate to the tropics was carried out for quantitatively assessing carbon loss from the soil under several scenarios of global warming, based on the model of soil carbon cycling in forest ecosystems (Nakane et al. 1984, 1987 and Nakane 1992). (J.P.N.)

The Influence of Direct and Indirect Speech on Source Memory

Directory of Open Access Journals (Sweden)

Anita Eerland

2018-02-01

Full Text Available People perceive the same situation described in direct speech (e.g., John said, “I like the food at this restaurant” as more vivid and perceptually engaging than described in indirect speech (e.g., John said that he likes the food at the restaurant. So, if direct speech enhances the perception of vividness relative to indirect speech, what are the effects of using indirect speech? In four experiments, we examined whether the use of direct and indirect speech influences the comprehender’s memory for the identity of the speaker. Participants read a direct or an indirect speech version of a story and then addressed statements to one of the four protagonists of the story in a memory task. We found better source memory at the level of protagonist gender after indirect than direct speech (Exp. 1–3. When the story was rewritten to make the protagonists more distinctive, we also found an effect of speech type on source memory at the level of the individual, with better memory after indirect than direct speech (Exp. 3–4. Memory for the content of the story, however, was not influenced by speech type (Exp. 4. While previous research showed that direct speech may enhance memory for how something was said, we conclude that indirect speech enhances memory for who said what.

The new control system of J-TEXT divertor power supply system using J-TEXT real-time framework

Energy Technology Data Exchange (ETDEWEB)

Zhang, Ming; Zheng, Guozhen; Chen, Zhi [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China); College of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan 430074 (China); Zheng, Wei, E-mail: zhengwei@hust.edu.cn [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China); College of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan 430074 (China); Yuan, Tao; Li, Yang [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China); College of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan 430074 (China)

2016-11-15

Highlights: • The most highlight of this paper is the J-TEXT Real-Time Framework (JRTF). JRTF is a flexible real-time software framework which allows users to develop real-time applications rapidly without compromise on the performance. It makes a clear separation between control functions and hard/software administration, developers just need to focus on the control logic and algorithms. • The JRTF based control system can achieve a precise control loop cycle of 1 ms and a jitter under 0.01 ms on Linux operation system. The real-time performance meets the requirement of the real-time control tasks in J-TEXT. • Several days of operation with no faults were already achieved with the system running and in real-time 8 h per day. The stability of the new system is qualified for discharging experiment. - Abstract: The J-TEXT divertor power supply system is designed as a parallel connection, 12-pulse rectifier which is powered by a 100 MVA pulse generator unit. To achieve robust current feedback control, high performance real-time control system is required. The new control system adopts a more powerful software framework named J-TEXT real-time framework (JRTF). JRTF is a flexible real-time software framework designed for the implementation of real-time control systems. A JRTF application contains various Application Blocks (AB) which execute specific functions such as feedback computing and protection. JRTF is compatible with ITER standard PFC (Plant Fast Controller) hardware and ITER CODAC (Control, Data Access and Communication) Core software, so it can be monitored and configured by any EPICS based control system. The hardware of the new control system is upgraded to standard ITER fast controller which are much faster and more reliable than former controllers. This control system is the first application of JRTF, and the result shows that the new control system is running properly and stably. It provides an instance for real-time control schemes in J-TEXT, and

The new control system of J-TEXT divertor power supply system using J-TEXT real-time framework

International Nuclear Information System (INIS)

Zhang, Ming; Zheng, Guozhen; Chen, Zhi; Zheng, Wei; Yuan, Tao; Li, Yang

2016-01-01

Highlights: • The most highlight of this paper is the J-TEXT Real-Time Framework (JRTF). JRTF is a flexible real-time software framework which allows users to develop real-time applications rapidly without compromise on the performance. It makes a clear separation between control functions and hard/software administration, developers just need to focus on the control logic and algorithms. • The JRTF based control system can achieve a precise control loop cycle of 1 ms and a jitter under 0.01 ms on Linux operation system. The real-time performance meets the requirement of the real-time control tasks in J-TEXT. • Several days of operation with no faults were already achieved with the system running and in real-time 8 h per day. The stability of the new system is qualified for discharging experiment. - Abstract: The J-TEXT divertor power supply system is designed as a parallel connection, 12-pulse rectifier which is powered by a 100 MVA pulse generator unit. To achieve robust current feedback control, high performance real-time control system is required. The new control system adopts a more powerful software framework named J-TEXT real-time framework (JRTF). JRTF is a flexible real-time software framework designed for the implementation of real-time control systems. A JRTF application contains various Application Blocks (AB) which execute specific functions such as feedback computing and protection. JRTF is compatible with ITER standard PFC (Plant Fast Controller) hardware and ITER CODAC (Control, Data Access and Communication) Core software, so it can be monitored and configured by any EPICS based control system. The hardware of the new control system is upgraded to standard ITER fast controller which are much faster and more reliable than former controllers. This control system is the first application of JRTF, and the result shows that the new control system is running properly and stably. It provides an instance for real-time control schemes in J-TEXT, and

Indirect reciprocity and the evolution of "moral signals"

Science.gov (United States)

Smead, Rory

2010-01-01

Signals regarding the behavior of others are an essential element of human moral systems and there are important evolutionary connections between language and large-scale cooperation. In particular, social communication may be required for the reputation tracking needed to stabilize indirect reciprocity. Additionally, scholars have suggested that the benefits of indirect reciprocity may have been important for the evolution of language and that social signals may have coevolved with large-scale cooperation. This paper investigates the possibility of such a coevolution. Using the tools of evolutionary game theory, we present a model that incorporates primitive "moral signaling" into a simple setting of indirect reciprocity. This model reveals some potential difficulties for the evolution of "moral signals." We find that it is possible for "moral signals" to evolve alongside indirect reciprocity, but without some external pressure aiding the evolution of a signaling system, such a coevolution is unlikely.

46 CFR 58.05-1 - Material, design and construction.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Material, design and construction. 58.05-1 Section 58.05... AUXILIARY MACHINERY AND RELATED SYSTEMS Main Propulsion Machinery § 58.05-1 Material, design and construction. (a) The material, design, construction, workmanship, and arrangement of main propulsion machinery...

Indirect self-destructiveness in individuals with schizophrenia

Directory of Open Access Journals (Sweden)

Konstantinos Tsirigotis

2017-06-01

Full Text Available Objective: To explore the indirect self-destructiveness syndrome in patients with schizophrenia. Methods: Two hundred individuals with paranoid schizophrenia (117 men and 83 women, mean age 37.15 years, all in remission, were examined using the Polish version of the Chronic Self-Destructiveness Scale. Two hundred well-matched healthy individuals served as a control group. Results: The intensity of indirect self-destructiveness was greater in the schizophrenia group than in controls. The intensity of each manifestation was as follows (in decreasing order: helplessness and passiveness in the face of difficulties (A5, personal and social neglects (A3, lack of planfulness (A4, poor health maintenance (A2, transgression and risk (A1. Conclusion: Patients with schizophrenia displayed more behaviors that were indirectly self-destructive than healthy controls; they scored better than healthy controls only on caring for their own health. The patients showed the lowest intensity of behaviors connected with the active form of indirect self-destructiveness, and the highest intensity of behaviors connected with the passive form. These findings may enable delivery of more effective forms of pharmacological and psychosocial help to patients with schizophrenia.

Epidemic spreading through direct and indirect interactions.

Science.gov (United States)

Ganguly, Niloy; Krueger, Tyll; Mukherjee, Animesh; Saha, Sudipta

2014-09-01

In this paper we study the susceptible-infected-susceptible epidemic dynamics, considering a specialized setting where popular places (termed passive entities) are visited by agents (termed active entities). We consider two types of spreading dynamics: direct spreading, where the active entities infect each other while visiting the passive entities, and indirect spreading, where the passive entities act as carriers and the infection is spread via them. We investigate in particular the effect of selection strategy, i.e., the way passive entities are chosen, in the spread of epidemics. We introduce a mathematical framework to study the effect of an arbitrary selection strategy and derive formulas for prevalence, extinction probabilities, and epidemic thresholds for both indirect and direct spreading. We also obtain a very simple relationship between the extinction probability and the prevalence. We pay special attention to preferential selection and derive exact formulas. The analysis reveals that an increase in the diversity in the selection process lowers the epidemic thresholds. Comparing the direct and indirect spreading, we identify regions in the parameter space where the prevalence of the indirect spreading is higher than the direct one.

An indecent proposal: the dual functions of indirect speech.

Science.gov (United States)

Chakroff, Aleksandr; Thomas, Kyle A; Haque, Omar S; Young, Liane

2015-01-01

People often use indirect speech, for example, when trying to bribe a police officer by asking whether there might be "a way to take care of things without all the paperwork." Recent game theoretic accounts suggest that a speaker uses indirect speech to reduce public accountability for socially risky behaviors. The present studies examine a secondary function of indirect speech use: increasing the perceived moral permissibility of an action. Participants report that indirect speech is associated with reduced accountability for unethical behavior, as well as increased moral permissibility and increased likelihood of unethical behavior. Importantly, moral permissibility was a stronger mediator of the effect of indirect speech on likelihood of action, for judgments of one's own versus others' unethical action. In sum, the motorist who bribes the police officer with winks and nudges may not only avoid public punishment but also maintain the sense that his actions are morally permissible. Copyright © 2014 Cognitive Science Society, Inc.

Performance analysis of a potassium-steam two stage vapour cycle

International Nuclear Information System (INIS)

Mitachi, Kohshi; Saito, Takeshi

1983-01-01

It is an important subject to raise the thermal efficiency in thermal power plants. In present thermal power plants which use steam cycle, the plant thermal efficiency has already reached 41 to 42 %, steam temperature being 839 K, and steam pressure being 24.2 MPa. That is, the thermal efficiency in a steam cycle is facing a limit. In this study, analysis was made on the performance of metal vapour/steam two-stage Rankine cycle obtained by combining a metal vapour cycle with a present steam cycle. Three different combinations using high temperature potassium regenerative cycle and low temperature steam regenerative cycle, potassium regenerative cycle and steam reheat and regenerative cycle, and potassium bleed cycle and steam reheat and regenerative cycle were systematically analyzed for the overall thermal efficiency, the output ratio and the flow rate ratio, when the inlet temperature of a potassium turbine, the temperature of a potassium condenser, and others were varied. Though the overall thermal efficiency was improved by lowering the condensing temperature of potassium vapour, it is limited by the construction because the specific volume of potassium in low pressure section increases greatly. In the combinatipn of potassium vapour regenerative cycle with steam regenerative cycle, the overall thermal efficiency can be 58.5 %, and also 60.2 % if steam reheat and regenerative cycle is employed. If a cycle to heat steam with the bled vapor out of a potassium vapour cycle is adopted, the overall thermal efficiency of 63.3 % is expected. (Wakatsuki, Y.)

Observation of ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ.

Science.gov (United States)

Ablikim, M; Achasov, M N; Ai, X C; Albayrak, O; Albrecht, M; Ambrose, D J; Amoroso, A; An, F F; An, Q; Bai, J Z; Baldini Ferroli, R; Ban, Y; Bennett, D W; Bennett, J V; Bertani, M; Bettoni, D; Bian, J M; Bianchi, F; Boger, E; Boyko, I; Briere, R A; Cai, H; Cai, X; Cakir, O; Calcaterra, A; Cao, G F; Cetin, S A; Chang, J F; Chelkov, G; Chen, G; Chen, H S; Chen, H Y; Chen, J C; Chen, M L; Chen, S; Chen, S J; Chen, X; Chen, X R; Chen, Y B; Cheng, H P; Chu, X K; Cibinetto, G; Dai, H L; Dai, J P; Dbeyssi, A; Dedovich, D; Deng, Z Y; Denig, A; Denysenko, I; Destefanis, M; De Mori, F; Ding, Y; Dong, C; Dong, J; Dong, L Y; Dong, M Y; Dou, Z L; Du, S X; Duan, P F; Fan, J Z; Fang, J; Fang, S S; Fang, X; Fang, Y; Farinelli, R; Fava, L; Fedorov, O; Feldbauer, F; Felici, G; Feng, C Q; Fioravanti, E; Fritsch, M; Fu, C D; Gao, Q; Gao, X L; Gao, X Y; Gao, Y; Gao, Z; Garzia, I; Goetzen, K; Gong, L; Gong, W X; Gradl, W; Greco, M; Gu, M H; Gu, Y T; Guan, Y H; Guo, A Q; Guo, L B; Guo, R P; Guo, Y; Guo, Y P; Haddadi, Z; Hafner, A; Han, S; Hao, X Q; Harris, F A; He, K L; Held, T; Heng, Y K; Hou, Z L; Hu, C; Hu, H M; Hu, J F; Hu, T; Hu, Y; Huang, G S; Huang, J S; Huang, X T; Huang, X Z; Huang, Y; Huang, Z L; Hussain, T; Ji, Q; Ji, Q P; Ji, X B; Ji, X L; Jiang, L W; Jiang, X S; Jiang, X Y; Jiao, J B; Jiao, Z; Jin, D P; Jin, S; Johansson, T; Julin, A; Kalantar-Nayestanaki, N; Kang, X L; Kang, X S; Kavatsyuk, M; Ke, B C; Kiese, P; Kliemt, R; Kloss, B; Kolcu, O B; Kopf, B; Kornicer, M; Kupsc, A; Kühn, W; Lange, J S; Lara, M; Larin, P; Leng, C; Li, C; Li, Cheng; Li, D M; Li, F; Li, F Y; Li, G; Li, H B; Li, H J; Li, J C; Li, Jin; Li, K; Li, K; Li, Lei; Li, P R; Li, Q Y; Li, T; Li, W D; Li, W G; Li, X L; Li, X N; Li, X Q; Li, Y B; Li, Z B; Liang, H; Liang, Y F; Liang, Y T; Liao, G R; Lin, D X; Liu, B; Liu, B J; Liu, C X; Liu, D; Liu, F H; Liu, Fang; Liu, Feng; Liu, H B; Liu, H H; Liu, H H; Liu, H M; Liu, J; Liu, J B; Liu, J P; Liu, J Y; Liu, K; Liu, K Y; Liu, L D; Liu, P L; Liu, Q; Liu, S B; Liu, X; Liu, Y B; Liu, Z A; Liu, Zhiqing; Loehner, H; Lou, X C; Lu, H J; Lu, J G; Lu, Y; Lu, Y P; Luo, C L; Luo, M X; Luo, T; Luo, X L; Lyu, X R; Ma, F C; Ma, H L; Ma, L L; Ma, M M; Ma, Q M; Ma, T; Ma, X N; Ma, X Y; Ma, Y M; Maas, F E; Maggiora, M; Mao, Y J; Mao, Z P; Marcello, S; Messchendorp, J G; Min, J; Mitchell, R E; Mo, X H; Mo, Y J; Morales Morales, C; Muchnoi, N Yu; Muramatsu, H; Nefedov, Y; Nerling, F; Nikolaev, I B; Ning, Z; Nisar, S; Niu, S L; Niu, X Y; Olsen, S L; Ouyang, Q; Pacetti, S; Pan, Y; Patteri, P; Pelizaeus, M; Peng, H P; Peters, K; Pettersson, J; Ping, J L; Ping, R G; Poling, R; Prasad, V; Qi, H R; Qi, M; Qian, S; Qiao, C F; Qin, L Q; Qin, N; Qin, X S; Qin, Z H; Qiu, J F; Rashid, K H; Redmer, C F; Ripka, M; Rong, G; Rosner, Ch; Ruan, X D; Sarantsev, A; Savrié, M; Schoenning, K; Schumann, S; Shan, W; Shao, M; Shen, C P; Shen, P X; Shen, X Y; Sheng, H Y; Shi, M; Song, W M; Song, X Y; Sosio, S; Spataro, S; Sun, G X; Sun, J F; Sun, S S; Sun, X H; Sun, Y J; Sun, Y Z; Sun, Z J; Sun, Z T; Tang, C J; Tang, X; Tapan, I; Thorndike, E H; Tiemens, M; Ullrich, M; Uman, I; Varner, G S; Wang, B; Wang, B L; Wang, D; Wang, D Y; Wang, K; Wang, L L; Wang, L S; Wang, M; Wang, P; Wang, P L; Wang, S G; Wang, W; Wang, W P; Wang, X F; Wang, Y; Wang, Y D; Wang, Y F; Wang, Y Q; Wang, Z; Wang, Z G; Wang, Z H; Wang, Z Y; Wang, Z Y; Weber, T; Wei, D H; Wei, J B; Weidenkaff, P; Wen, S P; Wiedner, U; Wolke, M; Wu, L H; Wu, L J; Wu, Z; Xia, L; Xia, L G; Xia, Y; Xiao, D; Xiao, H; Xiao, Z J; Xie, Y G; Xiu, Q L; Xu, G F; Xu, J J; Xu, L; Xu, Q J; Xu, Q N; Xu, X P; Yan, L; Yan, W B; Yan, W C; Yan, Y H; Yang, H J; Yang, H X; Yang, L; Yang, Y X; Ye, M; Ye, M H; Yin, J H; Yu, B X; Yu, C X; Yu, J S; Yuan, C Z; Yuan, W L; Yuan, Y; Yuncu, A; Zafar, A A; Zallo, A; Zeng, Y; Zeng, Z; Zhang, B X; Zhang, B Y; Zhang, C; Zhang, C C; Zhang, D H; Zhang, H H; Zhang, H Y; Zhang, J; Zhang, J J; Zhang, J L; Zhang, J Q; Zhang, J W; Zhang, J Y; Zhang, J Z; Zhang, K; Zhang, L; Zhang, S Q; Zhang, X Y; Zhang, Y; Zhang, Y H; Zhang, Y N; Zhang, Y T; Zhang, Yu; Zhang, Z H; Zhang, Z P; Zhang, Z Y; Zhao, G; Zhao, J W; Zhao, J Y; Zhao, J Z; Zhao, Lei; Zhao, Ling; Zhao, M G; Zhao, Q; Zhao, Q W; Zhao, S J; Zhao, T C; Zhao, Y B; Zhao, Z G; Zhemchugov, A; Zheng, B; Zheng, J P; Zheng, W J; Zheng, Y H; Zhong, B; Zhou, L; Zhou, X; Zhou, X K; Zhou, X R; Zhou, X Y; Zhu, K; Zhu, K J; Zhu, S; Zhu, S H; Zhu, X L; Zhu, Y C; Zhu, Y S; Zhu, Z A; Zhuang, J; Zotti, L; Zou, B S; Zou, J H

2017-06-02

Using 4.479×10^{8}  ψ(3686) events collected with the BESIII detector, we search for the decays ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ, where J=0, 1, 2. The decays ψ(3686)→e^{+}e^{-}χ_{cJ} and χ_{cJ}→e^{+}e^{-}J/ψ are observed for the first time. The measured branching fractions are B(ψ(3686)→e^{+}e^{-}χ_{cJ})=(11.7±2.5±1.0)×10^{-4}, (8.6±0.3±0.6)×10^{-4}, (6.9±0.5±0.6)×10^{-4} for J=0, 1, 2, and B(χ_{cJ}→e^{+}e^{-}J/ψ)=(1.51±0.30±0.13)×10^{-4}, (3.73±0.09±0.25)×10^{-3}, (2.48±0.08±0.16)×10^{-3} for J=0, 1, 2, respectively. The ratios of the branching fractions B(ψ(3686)→e^{+}e^{-}χ_{cJ})/B(ψ(3686)→γχ_{cJ}) and B(χ_{cJ}→e^{+}e^{-}J/ψ)/B(χ_{cJ}→γJ/ψ) are also reported. Also, the α values of helicity angular distributions of the e^{+}e^{-} pair are determined for ψ(3686)→e^{+}e^{-}χ_{c1,2} and χ_{c1,2}→e^{+}e^{-}J/ψ.

Exact computation of the 3-j and 6-j symbols

International Nuclear Information System (INIS)

Lai Shantao; Chiu Yingnan

1990-01-01

A simple FORTRAN program for the exaxt computation of 3-j and 6-j symbols has been written for the VAX with VMS version v5.1 in our university's computing center. It goes beyond and contains all of the 3-j and 6-j symbols evaluated in the book by M. Rotenberg, R. Bivins, N. Metropolis and J.K. Wooten Jr. The 3-j symbols up to (30/m 1 30/m 2 30/m 3 ) and 6-j symbols up to {20/20 20/20 20/20} can be computed exactly by this program. Approximate values for larger j's up to (200/m 1 200/m 2 200/m 3 ) and {200/200 200/200 200/220} can also be computed by this program. (orig.)

Indirect techniques in nuclear astrophysics: a review

International Nuclear Information System (INIS)

Tribble, R E; Mukhamedzhanov, A M; Bertulani, C A; Cognata, M La; Spitaleri, C

2014-01-01

In this review, we discuss the present status of three indirect techniques that are used to determine reaction rates for stellar burning processes, asymptotic normalization coefficients, the Trojan Horse method and Coulomb dissociation. A comprehensive review of the theory behind each of these techniques is presented. This is followed by an overview of the experiments that have been carried out using these indirect approaches. (review article)

Indirect techniques in nuclear astrophysics: a review.

Science.gov (United States)

Tribble, R E; Bertulani, C A; Cognata, M La; Mukhamedzhanov, A M; Spitaleri, C

2014-10-01

In this review, we discuss the present status of three indirect techniques that are used to determine reaction rates for stellar burning processes, asymptotic normalization coefficients, the Trojan Horse method and Coulomb dissociation. A comprehensive review of the theory behind each of these techniques is presented. This is followed by an overview of the experiments that have been carried out using these indirect approaches.

Decoupling the direct and indirect effects of climate on plant litter decomposition: Accounting for stress-induced modifications in plant chemistry.

Science.gov (United States)

Suseela, Vidya; Tharayil, Nishanth

2018-04-01

Decomposition of plant litter is a fundamental ecosystem process that can act as a feedback to climate change by simultaneously influencing both the productivity of ecosystems and the flux of carbon dioxide from the soil. The influence of climate on decomposition from a postsenescence perspective is relatively well known; in particular, climate is known to regulate the rate of litter decomposition via its direct influence on the reaction kinetics and microbial physiology on processes downstream of tissue senescence. Climate can alter plant metabolism during the formative stage of tissues and could shape the final chemical composition of plant litter that is available for decomposition, and thus indirectly influence decomposition; however, these indirect effects are relatively poorly understood. Climatic stress disrupts cellular homeostasis in plants and results in the reprogramming of primary and secondary metabolic pathways, which leads to changes in the quantity, composition, and organization of small molecules and recalcitrant heteropolymers, including lignins, tannins, suberins, and cuticle within the plant tissue matrix. Furthermore, by regulating metabolism during tissue senescence, climate influences the resorption of nutrients from senescing tissues. Thus, the final chemical composition of plant litter that forms the substrate of decomposition is a combined product of presenescence physiological processes through the production and resorption of metabolites. The changes in quantity, composition, and localization of the molecular construct of the litter could enhance or hinder tissue decomposition and soil nutrient cycling by altering the recalcitrance of the lignocellulose matrix, the composition of microbial communities, and the activity of microbial exo-enzymes via various complexation reactions. Also, the climate-induced changes in the molecular composition of litter could differentially influence litter decomposition and soil nutrient cycling. Compared

Diary as an Instrument of Philosophic Self-research in Creative Work of J.-P. Sartre

Directory of Open Access Journals (Sweden)

Natalya S. Shurinova

2016-12-01

Full Text Available The article examines the features of diary genre in the works of J.-P. Sartre on the text material, demonstrating an affinity with diary prose, – the novel «Nausea» and «Diary of a strange war». We proceed from the assumption that the relevance of this form is due to Sartre’s genre traits, productive for the formulation of an existential statement. Among them are: a special stylistic organization of the text, the synchronicity of unfinished diary, as well as the possibility of introducing in the text of the indirect recipient and the similarity of the genre with the epistolary form. Each of these features enables Sartre to actualize their own philosophical principles and ideas: openness of the existential project, intentionality of consciousness and the need to examine the person in the aspect of its perception of the world, the senselessness of introspection and self-knowledge of the other. During the analysis we refer to the works of Russian (E.M. Evnin, S.L. Fokin and French Sartre-experts (J.F. Luetta, M. Comte, J. Degi, J. Simon, as well as theoretical studies of the genre (works of Y.M. Lotman, O. Yegorov, A.A. Zaliznyak, L.N. Letyagin, A. Girard, F. Lejeune.

The Indirect cost of illness in Africa

Directory of Open Access Journals (Sweden)

Joses Muthuri Kirigia

2018-06-01

Full Text Available Background: The current study estimated (a the indirect costs associated with non-fatal disability and premature death across a wide range of diseases and health conditions in Africa in 2015 and (b the potential savings that could be accrued if countries were to meet the 3 health targets of the substainable development goal (SDG compared to the costs under the status quo. Methods: This study used the lost output or human capital approach to quantify the gross domestic product (GDP losses associated with the disability-adjusted-life-years (DALYs lost due to all causes by age group as well as by country economic classification (Group 1: 10 high/upper-middle income countries; Group 2: 17 lower-middle income countries; and Group 3: 27 low income countries. Results: The expected indirect cost of the 704,765,879 DALYs lost in Africa in 2015 was Int$ 2,983,187,560,197. Of this amount, 25.17%, 57.84% and 16.99% were incurred by the economies of the countries comprising Group 1, Group 2 and Group 3, respectively. Of the total continental indirect cost, 36.9%, 10.5%, 13.7%, 17.0%, 7.6%, 6.8% and 7.5% were associated with people aged 0-4, 5-14, 15-29, 30-49, 50-59, 60-69 and 70 years or older, respectively. Most of the total indirect cost (56.61% was attributable to maternal conditions, AIDS, tuberculosis (TB, malaria, neglected tropicald diseases (NTDs, non-communicable diseases and traffic injuries. Approximately half (47% of this cost could be avoided (or saved every year if the 3 (health targets of the SDG were fully met. Conclusion: The study estimated the total indirect cost of illness due to all causes by age group and country economic classification. The annual indirect cost is substantial. The findings contained in this paper suggest that health system strengthening should focus on both rich and poor countries, people of all ages and specific disease categories.

Selection for components of complex characteristics - indirect selection

International Nuclear Information System (INIS)

Haensel, H.

1984-01-01

A hierarchy of complexity exists in plant characteristics. The efficiency of indirect selection for a complex characteristic by a sub-trait depends on the heritability of the complex characteristic (hsub(c)), the heritability of the sub-trait (hsub(s)), and the genotypic correlation between sub-trait and complex characteristic (rsub(s.c)). In 1961 hsub(s)Xrsub(s.c)>hsub(c) was postulated, when indirect selection becomes more efficient than direct selection. Numerical examples for this relationship are given and a table for indirect selection for yield in wheat is elaborated. Efficiency ranking of sub-traits in indirect selection may change with climate, conditions of cultivation, the level of other sub-traits, the level of the complex characteristic already reached by breeding, and the breeding material. An example shows that regression analysis for different sub-traits on the same complex characteristic, and an estimation of the differences of the within - and the between - variety slopes, may help to select the more efficient sub-trait. In another example, where simultaneous selection was made for two polygenic characteristics, one directly and the other indirectly by two sub-traits, less than half the F 5 -lines had to be continued, when using the more efficient sub-trait. (author)

Indirect reciprocity in three types of social dilemmas.

Science.gov (United States)

Nakamura, Mitsuhiro; Ohtsuki, Hisashi

2014-08-21

Indirect reciprocity is a key mechanism for the evolution of human cooperation. Previous studies explored indirect reciprocity in the so-called donation game, a special class of Prisoner's Dilemma (PD) with unilateral decision making. A more general class of social dilemmas includes Snowdrift (SG), Stag Hunt (SH), and PD games, where two players perform actions simultaneously. In these simultaneous-move games, moral assessments need to be more complex; for example, how should we evaluate defection against an ill-reputed, but now cooperative, player? We examined indirect reciprocity in the three social dilemmas and identified twelve successful social norms for moral assessments. These successful norms have different principles in different dilemmas for suppressing cheaters. To suppress defectors, any defection against good players is prohibited in SG and PD, whereas defection against good players may be allowed in SH. To suppress unconditional cooperators, who help anyone and thereby indirectly contribute to jeopardizing indirect reciprocity, we found two mechanisms: indiscrimination between actions toward bad players (feasible in SG and PD) or punishment for cooperation with bad players (effective in any social dilemma). Moreover, we discovered that social norms that unfairly favor reciprocators enhance robustness of cooperation in SH, whereby reciprocators never lose their good reputation. Copyright © 2014 Elsevier Ltd. All rights reserved.

On the comprehensibility and perceived privacy protection of indirect questioning techniques.

Science.gov (United States)

Hoffmann, Adrian; Waubert de Puiseau, Berenike; Schmidt, Alexander F; Musch, Jochen

2017-08-01

On surveys that assess sensitive personal attributes, indirect questioning aims at increasing respondents' willingness to answer truthfully by protecting confidentiality. However, the assumption that subjects understand questioning procedures fully and trust them to protect their privacy is rarely tested. In a scenario-based design, we compared four indirect questioning procedures in terms of their comprehensibility and perceived privacy protection. All indirect questioning techniques were found to be less comprehensible by respondents than a conventional direct question used for comparison. Less-educated respondents experienced more difficulties when confronted with any indirect questioning technique. Regardless of education, the crosswise model was found to be the most comprehensible among the four indirect methods. Indirect questioning in general was perceived to increase privacy protection in comparison to a direct question. Unexpectedly, comprehension and perceived privacy protection did not correlate. We recommend assessing these factors separately in future evaluations of indirect questioning.

Experimental investigation of novel indirect solar cooker with indoor PCM thermal storage and cooking unit

International Nuclear Information System (INIS)

Hussein, H.M.S.; El-Ghetany, H.H.; Nada, S.A.

2008-01-01

In the present study, a novel indirect solar cooker with outdoor elliptical cross section, wickless heat pipes, flat-plate solar collector and integrated indoor PCM thermal storage and cooking unit is designed, constructed and tested under actual meteorological conditions of Giza, Egypt. Two plane reflectors are used to enhance the insolation falling on the cooker's collector, while magnesium nitrate hexahydrate (T m = 89 deg. C, latent heat of fusion 134 kJ/kg) is used as the PCM inside the indoor cooking unit of the cooker. It is found that the average daily enhancement in the solar radiation incident on the collector surface by the south and north facing reflectors is about 24%. Different experiments have been performed on the solar cooker without load and with different loads at different loading times to study the possibility of benefit from the virtues of the elliptical cross section wickless heat pipes and PCMs in indirect solar cookers to cook food at noon and evening and to keep food warm at night and in early morning. The results indicate that the present solar cooker can be used successfully for cooking different kinds of meals at noon, afternoon and evening times, while it can be used for heating or keeping meals hot at night and early morning

Tipping and Concentration in Markets with Indirect Network Effects

OpenAIRE

Jean-Pierre H. Dubé; Günter J. Hitsch; Pradeep K. Chintagunta

2010-01-01

This paper develops a framework for measuring “tipping”—the increase in a firm's market share dominance caused by indirect network effects. Our measure compares the expected concentration in a market to the hypothetical expected concentration that would arise in the absence of indirect network effects. In practice, this measure requires a model that can predict the counterfactual market concentration under different parameter values capturing the strength of indirect network effects. We build...

The Adoption of Indirect Instruments of Monetary Policy

OpenAIRE

Tomás J. T. Baliño; Charles Enoch; William E. Alexander

1995-01-01

This paper examines the experience of implementing indirect instruments of monetary policy. The experiences of country studies illustrate the variety of circumstances under which indirect instruments of monetary policy have been introduced. Case Studies are presented for Chile, Egypt, Ghana, Indonesia, Mexico, New Zealand, and Poland.

The association between reality-based beliefs and indirectly experienced traumatization.

Science.gov (United States)

Shiri, Shimon; Wexler, Isaiah D; Schwartz, Isabella; Kadari, Michal; Kreitler, Shulamith

2010-12-01

The purpose of the study was to examine the association between belief types and the magnitude of indirect traumatization. Specific types of beliefs were defined in terms of the cognitive orientation theory, which is a cognitive-motivational approach to the understanding, predicting, and changing of behaviors. Belief types that were analyzed included beliefs about self, general beliefs, beliefs about norms, and goal beliefs as they relate to personal growth. Study participants included 38 rescuers (body handlers), 37 nurses, and 31 rehabilitation workers who treated injured civilians that had been exposed to politically motivated violence. The Cognitive Orientation for Posttraumatic Growth Scale was used to assess beliefs about personal growth. The Revised Posttraumatic Stress Disorder Inventory was administered to evaluate indirect traumatization. The results indicate that three of the four belief types related to personal growth were associated with the level of indirect traumatization. Optimistic and positive beliefs about self and general beliefs were associated with a lower level of indirect traumatization symptomatology, suggesting that these types of beliefs may counteract indirect traumatization. On the other hand, stronger goal beliefs were associated with greater indirect traumatization. The negative association between positive goal beliefs and indirect trauma may be related to the gap the individual perceives between the hoped-for ideals and the trauma-stricken reality. These results indicate the importance of cognitive beliefs and their possible role in determining the response to indirect traumatization.

Direct versus indirect detection of supersymmetric dark matter

International Nuclear Information System (INIS)

2003-01-01

This document gathers the slides that were presented during the workshop 'direct versus indirect detection of supersymmetric dark matter'(about 30 contributions). This workshop intended to bring together people from the particle theory community, astrophysicists and cosmologists, as well as experimentalists involved in the detection of dark matter. The aim is to generate a discussion about current and future strategies for detection of SUSY dark matter (with focus, but not exclusively, on neutralinos). Complementarities between accelerator, direct and indirect searches as well as a comparison between the uncertainties in direct and indirect searches of dark matter, are supposed to be discussed. Among the issues which will be addressed are: -) the crucial questions related to the structure of galaxies (local dark matter density, clumping, anomalous velocity distributions, etc.) ; -) the possibilities offered by the present and future experimental facilities for direct and indirect (photon, neutrino) searches; -) the potential for the discovery of SUSY at LHC and beyond; and -) the parameterization of the SUSY breaking models beyond the minimal versions

Direct and indirect influences of childhood abuse on depression symptoms in patients with major depressive disorder.

Science.gov (United States)

Hayashi, Yumi; Okamoto, Yasumasa; Takagaki, Koki; Okada, Go; Toki, Shigeru; Inoue, Takeshi; Tanabe, Hajime; Kobayakawa, Makoto; Yamawaki, Shigeto

2015-10-14

It is known that the onset, progression, and prognosis of major depressive disorder are affected by interactions between a number of factors. This study investigated how childhood abuse, personality, and stress of life events were associated with symptoms of depression in depressed people. Patients with major depressive disorder (N = 113, 58 women and 55 men) completed the Beck Depression Inventory-II (BDI-II), the Neuroticism Extroversion Openness Five Factor Inventory (NEO-FFI), the Child Abuse and Trauma Scale (CATS), and the Life Experiences Survey (LES), which are self-report scales. Results were analyzed with correlation analysis and structural equation modeling (SEM), by using SPSS AMOS 21.0. Childhood abuse directly predicted the severity of depression and indirectly predicted the severity of depression through the mediation of personality. Negative life change score of the LES was affected by childhood abuse, however it did not predict the severity of depression. This study is the first to report a relationship between childhood abuse, personality, adulthood life stresses and the severity of depression in depressed patients. Childhood abuse directly and indirectly predicted the severity of depression. These results suggest the need for clinicians to be receptive to the possibility of childhood abuse in patients suffering from depression. SEM is a procedure used for hypothesis modeling and not for causal modeling. Therefore, the possibility of developing more appropriate models that include other variables cannot be excluded.

7 CFR 58.211 - Packaging room for bulk products.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging room for bulk products. 58.211 Section 58... Service 1 Rooms and Compartments § 58.211 Packaging room for bulk products. A separate room or area shall... dust within the packaging room and where needed, a dust collector shall be provided and properly...

46 CFR 58.25-20 - Piping for steering gear.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Piping for steering gear. 58.25-20 Section 58.25-20... MACHINERY AND RELATED SYSTEMS Steering Gear § 58.25-20 Piping for steering gear. (a) Pressure piping must... the hydraulic system can be readily recharged from within the steering-gear compartment and must be...

Indirect-drive ablative Rayleigh-Taylor growth experiments on the Shenguang-II laser facility

Energy Technology Data Exchange (ETDEWEB)

Wu, J. F.; Fan, Z. F.; Zheng, W. D.; Wang, M.; Pei, W. B.; Zhu, S. P.; Zhang, W. Y. [Institute of Applied Physics and Computational Mathematics, Beijing 100094 (China); Miao, W. Y.; Yuan, Y. T.; Cao, Z. R.; Deng, B.; Jiang, S. E.; Liu, S. Y.; Ding, Y. K. [Research Center of Laser Fusion, China Academy of Engineering Physics, Mianyang 621900 (China); Wang, L. F.; Ye, W. H., E-mail: ye-wenhua@iapcm.ac.cn; He, X. T. [Institute of Applied Physics and Computational Mathematics, Beijing 100094 (China); HEDPS, Center for Applied Physics and Technology, Peking University, Beijing 100871 (China)

2014-04-15

In this research, a series of single-mode, indirect-drive, ablative Rayleigh-Taylor (RT) instability experiments performed on the Shenguang-II laser facility [X. T. He and W. Y. Zhang, Eur. Phys. J. D 44, 227 (2007)] using planar target is reported. The simulation results from the one-dimensional hydrocode for the planar foil trajectory experiment indicate that the energy flux at the hohlraum wall is obviously less than that at the laser entrance hole. Furthermore, the non-Planckian spectra of x-ray source can strikingly affect the dynamics of the foil flight and the perturbation growth. Clear images recorded by an x-ray framing camera for the RT growth initiated by small- and large-amplitude perturbations are obtained. The observed onset of harmonic generation and transition from linear to nonlinear growth regime is well predicted by two-dimensional hydrocode simulations.

J Chandrasekhar

Indian Academy of Sciences (India)

Resonance - Origins and Usage · J Chandrasekhar · More Details ... Molecule of the Month Maitotoxin - Holder of Two World Records · J Chandrasekhar ... Molecule of the Month Adamantane - A Plastic Piece of Diamond · J Chandrasekhar.

Indirect land use change and biofuel policy

International Nuclear Information System (INIS)

Kocoloski, Matthew; Griffin, W Michael; Matthews, H Scott

2009-01-01

Biofuel debates often focus heavily on carbon emissions, with parties arguing for (or against) biofuels solely on the basis of whether the greenhouse gas emissions of biofuels are less than (or greater than) those of gasoline. Recent studies argue that land use change leads to significant greenhouse gas emissions, making some biofuels more carbon intensive than gasoline. We argue that evaluating the suitability and utility of biofuels or any alternative energy source within the limited framework of plus and minus carbon emissions is too narrow an approach. Biofuels have numerous impacts, and policy makers should seek compromises rather than relying solely on carbon emissions to determine policy. Here, we estimate that cellulosic ethanol, despite having potentially higher life cycle CO 2 emissions (including from land use) than gasoline, would still be cost-effective at a CO 2 price of $80 per ton or less, well above estimated CO 2 mitigation costs for many alternatives. As an example of the broader approach to biofuel policy, we suggest the possibility of using the potential cost reductions of cellulosic ethanol relative to gasoline to balance out additional carbon emissions resulting from indirect land use change as an example of ways in which policies could be used to arrive at workable solutions.

Indirect land use change and biofuel policy

Science.gov (United States)

Kocoloski, Matthew; Griffin, W. Michael; Matthews, H. Scott

2009-09-01

Biofuel debates often focus heavily on carbon emissions, with parties arguing for (or against) biofuels solely on the basis of whether the greenhouse gas emissions of biofuels are less than (or greater than) those of gasoline. Recent studies argue that land use change leads to significant greenhouse gas emissions, making some biofuels more carbon intensive than gasoline. We argue that evaluating the suitability and utility of biofuels or any alternative energy source within the limited framework of plus and minus carbon emissions is too narrow an approach. Biofuels have numerous impacts, and policy makers should seek compromises rather than relying solely on carbon emissions to determine policy. Here, we estimate that cellulosic ethanol, despite having potentially higher life cycle CO2 emissions (including from land use) than gasoline, would still be cost-effective at a CO2 price of 80 per ton or less, well above estimated CO2 mitigation costs for many alternatives. As an example of the broader approach to biofuel policy, we suggest the possibility of using the potential cost reductions of cellulosic ethanol relative to gasoline to balance out additional carbon emissions resulting from indirect land use change as an example of ways in which policies could be used to arrive at workable solutions.

Theoretical and testing performance of an innovative indirect evaporative chiller

Energy Technology Data Exchange (ETDEWEB)

Jiang, Yi; Xie, Xiaoyun [Department of Building Science and Technology, Tsinghua University, Beijing (China)

2010-12-15

An indirect evaporative chiller is a device used to produce chilled water at a temperature between the wet bulb temperature and dew point of the outdoor air, which can be used in building HVAC systems. This article presents a theoretical analysis and practical performance of an innovative indirect evaporative chiller. First, the process of the indirect evaporative chiller is introduced; then, the matching characteristics of the process are presented and analyzed. It can be shown that the process that produces cold water by using dry air is a nearly-reversible process, so the ideal produced chilled water temperature of the indirect evaporative chiller can be set close to the dew point temperature of the chiller's inlet air. After the indirect evaporative chiller was designed, simulations were done to analyze the output water temperature, the cooling efficiency relative to the inlet dew point temperature, and the COP that the chiller can performance. The first installation of the indirect evaporative chiller of this kind has been run for 5 years in a building in the city of Shihezi. The tested output water temperature of the chiller is around 14-20 C, which is just in between of the outdoor wet bulb temperature and dew point. The tested COP{sub r,s} of the developed indirect evaporative chiller reaches 9.1. Compared with ordinary air conditioning systems, the indirect evaporative chiller can save more than 40% in energy consumption due to the fact that the only energy consumed is from pumps and fans. An added bonus is that the indirect evaporative chiller uses no CFCs that pollute to the aerosphere. The tested internal parameters, such as the water-air flow rate ratio and heat transfer area for each heat transfer process inside the chiller, were analyzed and compared with designed values. The tested indoor air conditions, with a room temperature of 23-27 C and relative humidity of 50-70%, proved that the developed practical indirect evaporative chiller

Preparation and antibacterial property of silver-containing mesoporous 58S bioactive glass

Energy Technology Data Exchange (ETDEWEB)

Zhu, Hailin; Hu, Chao [Key Laboratory of Fiber Materials and Processing Technology, Zhejiang Sci-Tech University, Hangzhou 310018 (China); Zhang, Fangfang [Zhejiang Provincial Hospital of Traditional Chinese Medicine, Hangzhou 310006 (China); Feng, Xinxing, E-mail: f0712@tom.com [The Quartermaster Research Institute of the General Logistic Department of CPLA, Beijing 100082 (China); Li, Jiuming; Liu, Tao [Key Laboratory of Fiber Materials and Processing Technology, Zhejiang Sci-Tech University, Hangzhou 310018 (China); Chen, Jianyong, E-mail: cjy@zstu.edu.cn [Key Laboratory of Fiber Materials and Processing Technology, Zhejiang Sci-Tech University, Hangzhou 310018 (China); Zhang, Jianchun [The Quartermaster Research Institute of the General Logistic Department of CPLA, Beijing 100082 (China)

2014-09-01

The modified mesoporous 58S bioglass (SM58S) was prepared through surface modification of the mesoporous 58S bioglass (M58S) with γ-aminopropyl triethoxysilane (KH550). The results of Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA) showed that the amino groups were grafted to the surface of M58S after modification with KH550. The silver-containing SM58S (Ag-SM58S) and M58S (Ag-M58S) were prepared by the dipping method. The Ag{sup +} loading capacity, release rate and antibacterial properties of Ag-SM58S and Ag-M58S were investigated. It is indicated that surface modification of M58S with KH550 can improve the Ag{sup +} loading capacity. The result of antibacterial property showed that Ag-SM58S exhibited significant anti-bacterial effects against Escherichia coli and Staphylococcus aureus. The sustained release of Ag{sup +} from Ag-SM58S for 768 h ensured excellent antibacterial property of Ag-SM58S. In vitro osteoblast proliferation and differentiation tests showed that Ag-SM58S was a good matrix for the growth of osteoblasts. Consequently, the results of the study suggested that Ag-SM58S might be a promising bone repair material. - Highlights: • The amino groups are grafted to the surface of M58S after modification with KH550. • Surface modification of M58S with KH550 can improve the Ag{sup +} loading capacity. • The sustained release of Ag{sup +} from Ag-SM58S ensures good antibacterial property.

Pratt & Whitney aircraft nuclear J-8 turbojet engine performance variation with radiator diameter

International Nuclear Information System (INIS)

Larson, John W.

1960-01-01

The variation of engine performance with liquid metal radiator diameter and flight altitude has been estimated for both the 1600F NaK and 1800F NaK radiators at Mach 0.6 and hot day atmospheric conditions. The net thrust, air flow and reactor power is presented in 3 figures for the Pratt & Whitney Aircraft J-58 engine with the 1600F NaK radiator. The net thrust, air flow and reactor power for the 1800F NaK radiator are also presented in figures.

Spiral correlations in frustrated one-dimensional spin-1/2 Heisenberg J1-J2-J3 ferromagnets

International Nuclear Information System (INIS)

Zinke, R; Richter, J; Drechsler, S-L

2010-01-01

We use the coupled cluster method for infinite chains complemented by exact diagonalization of finite periodic chains to discuss the influence of a third-neighbor exchange J 3 on the ground state of the spin- 1/2 Heisenberg chain with ferromagnetic nearest-neighbor interaction J 1 and frustrating antiferromagnetic next-nearest-neighbor interaction J 2 . A third-neighbor exchange J 3 might be relevant to describe the magnetic properties of the quasi-one-dimensional edge-shared cuprates, such as LiVCuO 4 or LiCu 2 O 2 . In particular, we calculate the critical point J 2 c as a function of J 3 , where the ferromagnetic ground state gives way for a ground state with incommensurate spiral correlations. For antiferromagnetic J 3 the ferro-spiral transition is always continuous and the critical values J 2 c of the classical and the quantum model coincide. On the other hand, for ferromagnetic J 3 ∼ 1 | the critical value J 2 c of the quantum model is smaller than that of the classical model. Moreover, the transition becomes discontinuous, i.e. the model exhibits a quantum tricritical point. We also calculate the height of the jump of the spiral pitch angle at the discontinuous ferro-spiral transition.

Origin of the -|A | T1 /2 term in the resistivity of disordered ZrAs1.58Se0.39

Science.gov (United States)

Gnida, Daniel

2018-04-01

Recently, Cichorek et al. have analyzed the magnetic-field-independent -|A | T1 /2 term in the resistivity of disordered ZrAs1.58Se0.39 within the Altshuler-Arononv model of electron-electron interaction in the presence of disorder [Phys. Rev. Lett. 117, 106601 (2016), 10.1103/PhysRevLett.117.106601]. Making the assumption that diffusion of conduction electrons in this compound is isotropic, they could not get quantitative agreement between the considered model and the experimental results. This led the authors to conclude that the singular T1 /2 contribution to the resistivity of ZrAs1.58Se0.39 could not be caused by electron-electron interaction but could only be explained by a two-channel Kondo effect. Here, we perform a detailed analysis of the -|A | T1 /2 correction to the resistivity of disordered ZrAs1.58Se0.39 using analogous Altshuler-Aronov relation but taking into account that the diffusion coefficient in the tetragonal ZrAs1.58Se0.39 is anisotropic. For the considered resistivity anisotropy, we found that the calculated values of the A coefficient are in very good agreement with those derived from the resistivity measurements. Moreover, analysis indicates that the values of the screening parameter λ(j =1 ) are close to zero, which satisfies the condition that the A coefficient does not depend on magnetic field. This shows that the magnetic-field-independent -|A | T1 /2 correction to the resistivity of disordered ZrAs1.58Se0.39 can be explained within the electron-electron interaction scenario in disordered metallic systems.

System markets: Indirect network effects in action, or inaction?

OpenAIRE

Binken, Jeroen

2010-01-01

textabstractIn this dissertation, I empirically examine system markets up close. More specifically I examine indirect network effects, both demand-side and supply-side indirect network effects. Indirect network effects are the source of positive feedback in system markets, or so network effect theory tells us. Systems are composed of complementary and interdependent products, such as hardware and software. For instance, a video game system is composed of the video game console, on the one han...

Indirect detection methods: Looking for what is not there

International Nuclear Information System (INIS)

Yeung, E.S.

1989-01-01

Indirect detection allows one to monitor species that normally do not give a response. It has grown from an intellectual curiosity to become an extremely useful tool. For volume displacement, polarimetry gives the best results. For charge displacement, ion chromatography and capillary zone electrophoresis are ideal situations for applying indirect fluorescence detection. LOD surpasses all but the most specialized detection schemes. Future developments in systems specially designed for indirect detection should make these schemes even more powerful

CONTRIBUTION OF INDIRECT TAXES

Directory of Open Access Journals (Sweden)

CHIRCULESCU MARIA FELICIA

2015-08-01

Full Text Available The work is based on the fact that at any time and in any society, taxation is regarded as undesirable for all taxpayers. The existence and it's manifestation is justified, because the operation of any company involves costs that must be covered by sufficient resources. Since ancient times, each state has adopted its own tax system, more or less perfected, as the state has experienced a greater or lesser economic and military power At the base of this work stays the fact that tax systems are a key factor influencing the overall efficiency of the economy. They determine the size tendency to save, invest and work, influencing the increase in production and employment, which is essential sights integral economic strategy, making tax reform an important component of economic reform. This paper aims to analyze the indirect taxes and their contribution to the public revenues in Romania, the purpose paper contains an analysis based on statistical series as indirect taxation is where tax harmonization was possible. Through analyzes, the paper aims to provide answers to the problem of the contradiction between the growing need for budgetary revenues, which entails a continuous amplification and diversification of taxation, on the one hand, and the need to stimulate economic development, on the other hand. The harmonization of indirect taxation had been achieved since this touches the free movement of goods and the freedom to supply services, not being able to say the same thing about direct taxation, which is why the European Community Treaty does not specify expressly the alignment of direct taxation, considering that direct taxation is a matter of Internal Policies that, for a country free option.

Violence as a Vicious Cycle

Directory of Open Access Journals (Sweden)

Huseyin Gulec

2012-03-01

Full Text Available Since the conclusion that the violence as a behavior is not (cannot be determined within an absolute genetic determinism has been reached for long years, environmental factors are increasingly examined. We witness that human behavior in society can easily convert into coping with stressful events with violence. Individual or social violence as a behavior has a similar pattern with violence committed in primitive society and by children. After a brief review of violence, its description, etiological theories and types, this article majorly focuses on children and their early and late response to violence. The purpose here is to draw attention to the individuals who were previously exposed to violence (either directly or indirectly resort to violence, perpetuating a vicious cycle.

Indirect taxes on food in Southern Brazil

Directory of Open Access Journals (Sweden)

Denize Mirian da Silva

2013-12-01

Full Text Available The objective of this paper is to estimate the indirect tax burden on food for ten income classes, based on income and household total expenditure in southern Brazil. Thus it can be seen as indirect taxes on foods affect the monetary income and consumption pattern of households. To reach the objectives proposed, will be used the Pintos-Payeras (2008 model. The database iscomposed by microdata from the Household Budgeting Survey (POF 2008-2009 and the tax regulations of the country and the southern states of Brazil. The results show that indirect taxes on food in Southern Brazil is regressive when based on income and expenditure of household , ie , the poorest people pay proportionately more taxes and have their consumption pattern highest taxed ICMS (Brazilian value added tax is the tax that contributes most to the regressivity.

Life cycle assessment of a willow bioenergy cropping system

International Nuclear Information System (INIS)

Heller, M.C.; Keoleian, G.A.; Volk, Timothy A.

2003-01-01

The environmental performance of willow biomass crop production systems in New York (NY) is analyzed using life cycle assessment (LCA) methodology. The base-case, which represents current practices in NY, produces 55 units of biomass energy per unit of fossil energy consumed over the biomass crop's 23-year lifetime. Inorganic nitrogen fertilizer inputs have a strong influence on overall system performance, accounting for 37% of the non-renewable fossil energy input into the system. Net energy ratio varies from 58 to below 40 as a function of fertilizer application rate, but application rate also has implications on the system nutrient balance. Substituting inorganic N fertilizer with sewage sludge biosolids increases the net energy ratio of the willow biomass crop production system by more than 40%. While CO 2 emitted in combusting dedicated biomass is balanced by CO 2 adsorbed in the growing biomass, production processes contribute to the system's net global warming potential. Taking into account direct and indirect fuel use, N 2 O emissions from applied fertilizer and leaf litter, and carbon sequestration in below ground biomass and soil carbon, the net greenhouse gas emissions total 0.68 g CO 2 eq. MJ biomassproduced -1 . Site specific parameters such as soil carbon sequestration could easily offset these emissions resulting in a net reduction of greenhouse gases. Assuming reasonable biomass transportation distance and energy conversion efficiencies, this study implies that generating electricity from willow biomass crops could produce 11 units of electricity per unit of fossil energy consumed. Results form the LCA support the assertion that willow biomass crops are sustainable from an energy balance perspective and contribute additional environmental benefits

Cycles of pedogenesis in the Bohemian Karst, Czech Republic

Czech Academy of Sciences Publication Activity Database

Žigová, Anna

2006-01-01

Roč. 8, - (2006) ISSN 1029-7006 R&D Projects: GA AV ČR IAA300130504 Institutional research plan: CEZ:AV0Z30130516 Keywords : cycles of pedogenesis * paleosols * soil micromorphology Subject RIV: DF - Soil Science http://www.cosis.net/abstracts/EGU06/05843/EGU06-J-05843-2.pdf

The nuclear fuel cycle, an overview

International Nuclear Information System (INIS)

Ballery, J.L.; Cazalet, J.; Hagemann, R.

1995-01-01

Because uranium is widely distributed on the face of the Earth, nuclear energy has a very large potential as an energy source in view of future depletion of fossil fuel reserves. Also future energy requirements will be very sizeable as populations of developing countries are often growing and make the energy question one of the major challenges for the coming decades. Today, nuclear contributes some 340 GWe to the energy requirements of the world. Present and future nuclear programs require an adequate fuel cycle industry, from mining, refining, conversion, enrichment, fuel fabrication, fuel reprocessing and the storage of the resulting wastes. The commercial fuel cycle activities amount to an annual business in the 7-8 billions of US Dollars in the hands of a large number of industrial operators. This paper gives details about companies and countries involved in each step of the fuel cycle and about the national strategies and options chosen regarding the back end of the fuel cycle (waste storage and reprocessing). These options are illustrated by considering the policy adopted in three countries (France, United Kingdom, Japan) versed in reprocessing. (J.S.). 13 figs., 2 tabs

7 CFR 58.635 - Pasteurization of the mix.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Pasteurization of the mix. 58.635 Section 58.635 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE...

Glucose feeds the TCA cycle via circulating lactate.

Science.gov (United States)

Hui, Sheng; Ghergurovich, Jonathan M; Morscher, Raphael J; Jang, Cholsoon; Teng, Xin; Lu, Wenyun; Esparza, Lourdes A; Reya, Tannishtha; Le Zhan; Yanxiang Guo, Jessie; White, Eileen; Rabinowitz, Joshua D

2017-11-02

Mammalian tissues are fuelled by circulating nutrients, including glucose, amino acids, and various intermediary metabolites. Under aerobic conditions, glucose is generally assumed to be burned fully by tissues via the tricarboxylic acid cycle (TCA cycle) to carbon dioxide. Alternatively, glucose can be catabolized anaerobically via glycolysis to lactate, which is itself also a potential nutrient for tissues and tumours. The quantitative relevance of circulating lactate or other metabolic intermediates as fuels remains unclear. Here we systematically examine the fluxes of circulating metabolites in mice, and find that lactate can be a primary source of carbon for the TCA cycle and thus of energy. Intravenous infusions of 13 C-labelled nutrients reveal that, on a molar basis, the circulatory turnover flux of lactate is the highest of all metabolites and exceeds that of glucose by 1.1-fold in fed mice and 2.5-fold in fasting mice; lactate is made primarily from glucose but also from other sources. In both fed and fasted mice, 13 C-lactate extensively labels TCA cycle intermediates in all tissues. Quantitative analysis reveals that during the fasted state, the contribution of glucose to tissue TCA metabolism is primarily indirect (via circulating lactate) in all tissues except the brain. In genetically engineered lung and pancreatic cancer tumours in fasted mice, the contribution of circulating lactate to TCA cycle intermediates exceeds that of glucose, with glutamine making a larger contribution than lactate in pancreatic cancer. Thus, glycolysis and the TCA cycle are uncoupled at the level of lactate, which is a primary circulating TCA substrate in most tissues and tumours.

Microbial biomass dynamics dominate N cycle responses to warming in a sub-arctic peatland

Science.gov (United States)

Weedon, J. T.; Aerts, R.; Kowalchuk, G. K.; van Bodegom, P. M.

2012-04-01

The balance of primary production and decomposition in sub-arctic peatlands may shift with climate change. Nitrogen availability will modulate this shift, but little is known about the drivers of soil nitrogen dynamics in these environments, and how they are influenced by rising soil temperatures. We used a long-term open top chamber warming experiment in Abisko, Sweden, to test for the interactive effects of spring warming, summer warming and winter snow addition on soil organic and inorganic nitrogen fluxes, potential activities of carbon and nitrogen cycle enzymes, and the structure of the soil-borne microbial communities. Summer warming increased the flux of soil organic nitrogen over the growing season, while simultaneously causing a seasonal decrease in microbial biomass, suggesting that N flux is driven by large late-season dieback of microbes. This change in N cycle dynamics was not reflected in any of the measured potential enzyme activities. Moreover, the soil microbial community structure was stable across treatments, suggesting non-specific microbial dieback. To further test whether the observed patterns were driven by direct temperature effects or indirect effects (via microbial biomass dynamics), we conducted follow-up controlled experiments in soil mesocosms. Experimental additions of dead microbial cells had stronger effects on N pool sizes and enzyme activities than either plant litter addition or a 5 °C alteration in incubation temperatures. Peat respiration was positively affected by both substrate addition and higher incubation temperatures, but the temperature-only effect was not sufficient to account for the increases in respiration observed in previous field experiments. We conclude that warming effects on peatland N cycling (and to some extent C cycling) are dominated by indirect effects, acting through alterations to the seasonal flux of microbe-derived organic matter. We propose that climate change models of soil carbon and nitrogen

Indirect Estimation of Selected Measures of Fertility and Marital ...

African Journals Online (AJOL)

DLHS6

2018-01-09

Jan 9, 2018 ... marital status distribution data of India especially of the 2011 census in deriving indirectly the fertility measures .... 2011 Census, Economic and Political weekly, EPW Vol. ... Indirect Estimates of Total Fertility Rate Using Child.

Direct versus indirect detection of supersymmetric dark matter

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-07-01

This document gathers the slides that were presented during the workshop 'direct versus indirect detection of supersymmetric dark matter'(about 30 contributions). This workshop intended to bring together people from the particle theory community, astrophysicists and cosmologists, as well as experimentalists involved in the detection of dark matter. The aim is to generate a discussion about current and future strategies for detection of SUSY dark matter (with focus, but not exclusively, on neutralinos). Complementarities between accelerator, direct and indirect searches as well as a comparison between the uncertainties in direct and indirect searches of dark matter, are supposed to be discussed. Among the issues which will be addressed are: -) the crucial questions related to the structure of galaxies (local dark matter density, clumping, anomalous velocity distributions, etc.) ; -) the possibilities offered by the present and future experimental facilities for direct and indirect (photon, neutrino) searches; -) the potential for the discovery of SUSY at LHC and beyond; and -) the parameterization of the SUSY breaking models beyond the minimal versions.

Estimating direct and indirect costs of premenstrual syndrome.

Science.gov (United States)

Borenstein, Jeff; Chiou, Chiun-Fang; Dean, Bonnie; Wong, John; Wade, Sally

2005-01-01

To quantify the economic impact of premenstrual syndrome (PMS) on the employer. Data were collected from 374 women aged 18-45 with regular menses. Direct costs were quantified using administrative claims of these patients and the Medicare Fee Schedule. Indirect costs were quantified by both self-reported days of work missed and lost productivity at work. Regression analyses were used to develop a model to project PMS-related direct and indirect costs. A total of 29.6% (n = 111) of the participants were diagnosed with PMS. A PMS diagnosis was associated with an average annual increase of $59 in direct costs (P increase in direct medical costs and a large increase in indirect costs.

The physics basis for ignition using indirect-drive targets on the National Ignition Facility

International Nuclear Information System (INIS)

Lindl, John D.; Amendt, Peter; Berger, Richard L.; Glendinning, S. Gail; Glenzer, Siegfried H.; Haan, Steven W.; Kauffman, Robert L.; Landen, Otto L.; Suter, Laurence J.

2004-01-01

drive temperature, drive symmetry, and hydrodynamic instability. This paper starts with a review of the NIF target designs that have formed the motivation for the goals of the target physics program. Following that are theoretical and experimental results from Nova and Omega relevant to the requirements of those targets. Some elements of this work were covered in a 1995 review of indirect-drive [J. D. Lindl, 'Development of the indirect-drive approach to inertial confinement fusion and the target physics basis for ignition and gain', Phys. Plasmas 2, 3933 (1995)]. In order to present as complete a picture as possible of the research that has been carried out on indirect drive, key elements of that earlier review are also covered here, along with a review of work carried out since 1995

Indirect methods for reference interval determination - review and recommendations.

Science.gov (United States)

Jones, Graham R D; Haeckel, Rainer; Loh, Tze Ping; Sikaris, Ken; Streichert, Thomas; Katayev, Alex; Barth, Julian H; Ozarda, Yesim

2018-04-19

Reference intervals are a vital part of the information supplied by clinical laboratories to support interpretation of numerical pathology results such as are produced in clinical chemistry and hematology laboratories. The traditional method for establishing reference intervals, known as the direct approach, is based on collecting samples from members of a preselected reference population, making the measurements and then determining the intervals. An alternative approach is to perform analysis of results generated as part of routine pathology testing and using appropriate statistical techniques to determine reference intervals. This is known as the indirect approach. This paper from a working group of the International Federation of Clinical Chemistry (IFCC) Committee on Reference Intervals and Decision Limits (C-RIDL) aims to summarize current thinking on indirect approaches to reference intervals. The indirect approach has some major potential advantages compared with direct methods. The processes are faster, cheaper and do not involve patient inconvenience, discomfort or the risks associated with generating new patient health information. Indirect methods also use the same preanalytical and analytical techniques used for patient management and can provide very large numbers for assessment. Limitations to the indirect methods include possible effects of diseased subpopulations on the derived interval. The IFCC C-RIDL aims to encourage the use of indirect methods to establish and verify reference intervals, to promote publication of such intervals with clear explanation of the process used and also to support the development of improved statistical techniques for these studies.

Identifying and Analyzing Strong Components of an Industrial Network Based on Cycle Degree

Directory of Open Access Journals (Sweden)

Zhiying Zhang

2016-01-01

Full Text Available In the era of big data and cloud computing, data research focuses not only on describing the individual characteristics but also on depicting the relationships among individuals. Studying dependence and constraint relationships among industries has aroused significant interest in the academic field. From the network perspective, this paper tries to analyze industrial relational structures based on cycle degree. The cycle degree of a vertex, that is, the number of cycles through a vertex in an industrial network, can describe the roles of the vertices of strong components in industrial circulation. In most cases, different vertices in a strong component have different cycle degrees, and the one with a larger cycle degree plays more important roles. However, the concept of cycle degree does not involve the lengths of the cycles, which are also important for circulations. The more indirect the relationship between two industries is, the weaker it is. In order to analyze strong components thoroughly, this paper proposes the concept of circular centrality taking into consideration the influence by two factors: the lengths and the numbers of cycles through a vertex. Exemplification indicates that a profound analysis of strong components in an industrial network can reveal the features of an economy.

Macrophage CGI-58 Attenuates Inflammatory Responsiveness via Promotion of PPARγ Signaling

Directory of Open Access Journals (Sweden)

Dan Yang

2016-02-01

Full Text Available Background/Aims: Comparative gene identification-58 (CGI-58, an adipose triglyceride lipase (ATGL coactivator, strongly promotes ATGL-mediated triglyceride (TG catabolism. Beyond its function in promoting lipolysis, other features of CGI-58 have been proposed. Here, we investigated the role of CGI-58 in the regulation of inflammatory responsiveness in macrophages. Methods: Macrophage-specific GCI-58 transgenic mice (TG and wild type mice (WT were fed a high fat diet (HFD, and RAW264.7 cells were treated with lipopolysaccharide (LPS. The peroxisome proliferator-activated receptor (PPAR signaling was detected. The inflammatory responsiveness and mitochondrial function were examined. Results: TG mice showed lower serum levels of proinflammatory cytokines and better mitochondrial function in macrophages compared with WT control. Knockdown of CGI-58 in RAW264.7 cells aggravated LPS-induced inflammation and mitochondrial dysfunction. CGI-58 overexpression and silencing in macrophages induced and inhibited PPARγ expression and activity, respectively. Most importantly, the PPARγ-specific agonist rosiglitazone significantly suppressed inflammation and mitochondrial dysfunction induced by CGI-58 deficiency. Furthermore, knockdown of PPARγ in macrophages significantly dampened the role of CGI-58 in suppression of inflammation and mitochondrial dysfunction. Interestingly, CGI-58 inhibited histone deacetylation and the recruitment of histone deacetylase (HDAC to the PPARγ promoter. Finally, ATGL deficiency did not affect inflammatory responsiveness and PPARγ signaling in macrophages. Conclusion: These results demonstrate that macrophage CGI-58 enhances PPARγ signaling and thus suppresses inflammatory responsiveness and mitochondrial dysfunction.

7 CFR 58.620 - Freezing and packaging rooms.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Freezing and packaging rooms. 58.620 Section 58.620 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards....620 Freezing and packaging rooms. The rooms used for freezing and packaging frozen desserts shall be...

7 CFR 58.524 - Packaging and general identification.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Packaging and general identification. 58.524 Section... Service 1 Operations and Operating Procedures § 58.524 Packaging and general identification. (a) Containers. Containers used for packaging cottage cheese shall be any commercially acceptable multiple use or...

46 CFR 58.60-9 - Industrial systems: Design.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Industrial systems: Design. 58.60-9 Section 58.60-9 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Industrial Systems and Components on Mobile Offshore Drilling Units (MODU...

46 CFR 58.60-7 - Industrial systems: Piping.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Industrial systems: Piping. 58.60-7 Section 58.60-7 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Industrial Systems and Components on Mobile Offshore Drilling Units (MODU...

46 CFR 58.60-5 - Industrial systems: Locations.

Science.gov (United States)

2010-10-01

... 46 Shipping 2 2010-10-01 2010-10-01 false Industrial systems: Locations. 58.60-5 Section 58.60-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING MAIN AND AUXILIARY MACHINERY AND RELATED SYSTEMS Industrial Systems and Components on Mobile Offshore Drilling Units (MODU...

Circumventing resistance: using values to indirectly change attitudes.

Science.gov (United States)

Blankenship, Kevin L; Wegener, Duane T; Murray, Renee A

2012-10-01

Most research on persuasion examines messages that directly address the attitude of interest. However, especially when message recipients are inclined to resist change, indirect methods might be more effective. Because values are rarely attacked and defended, value change could serve as a useful indirect route for attitude change. Attitudes toward affirmative action changed more when the value of equality was attacked (indirect change) than when affirmative action was directly attacked using the same message (Experiments 1-2). Changes in confidence in the value were responsible for the indirect change when the value was attacked (controlling for changes in favorability toward the value), whereas direct counterarguments to the message were responsible for the relative lack of change when the attitude was attacked directly (Experiment 2). Attacking the value of equality influenced attitudes toward policies related to the value but left policy attitudes unrelated to the value unchanged (Experiment 3). Finally, a manipulation of value confidence that left attitudes toward the value intact demonstrated similar confidence-based influences on policies related to the value of freedom (Experiment 4). Undermined value confidence also resulted in less confidence in the resulting policy attitudes controlling for the changes in the policy attitudes themselves (Experiments 3 and 4). Therefore, indirect change through value attacks presented a double threat--to both the policy attitudes and the confidence with which those policy attitudes were held (potentially leaving them open to additional influence).

A Polytime Algorithm Based on a Primal LP Model for the Scheduling Problem 1 vertical bar pmtn;p(j)=2;r(j)vertical bar Sigma w(j)C(j)

NARCIS (Netherlands)

Bouma, Harmen W.; Goldengorin, Boris; Lagakos, S; Perlovsky, L; Jha, M; Covaci, B; Zaharim, A; Mastorakis, N

2009-01-01

In this paper a Boolean Linear Programming (BLP) model is presented for the single machine scheduling problem 1 vertical bar pmtn; p(j) = 2;r(j)vertical bar Sigma w(j)C(j). The problem is a special case of the open problem 1 vertical bar pmtn; p(j) = p; r(j)vertical bar Sigma wj(g)C(j). We show that

Indirect methods for wake potential integration

International Nuclear Information System (INIS)

Zagorodnov, I.

2006-05-01

The development of the modern accelerator and free-electron laser projects requires to consider wake fields of very short bunches in arbitrary three dimensional structures. To obtain the wake numerically by direct integration is difficult, since it takes a long time for the scattered fields to catch up to the bunch. On the other hand no general algorithm for indirect wake field integration is available in the literature so far. In this paper we review the know indirect methods to compute wake potentials in rotationally symmetric and cavity-like three dimensional structures. For arbitrary three dimensional geometries we introduce several new techniques and test them numerically. (Orig.)

Investigation of possible phase transition of the frustrated spin-1/2 J 1-J 2-J 3 model on the square lattice.

Science.gov (United States)

Hu, Ai-Yuan; Wang, Huai-Yu

2017-09-05

The frustrated spin-1/2 J 1 -J 2 -J 3 antiferromagnet with exchange anisotropy on the two-dimensional square lattice is investigated. The exchange anisotropy is presented by η with 0 ≤ η J 1 , J 2 , J 3 and anisotropy on the possible phase transition of the Néel state and collinear state are studied comprehensively. Our results indicate that for J 3  > 0 there are upper limits [Formula: see text] and η c values. When 0 J 3  ≤ [Formula: see text] and 0 ≤ η ≤ η c , the Néel and collinear states have the same order-disorder transition point at J 2  = J 1 /2. Nevertheless, when the J 3 and η values beyond the upper limits, it is a paramagnetic phase at J 2  = J 1 /2. For J 3  J 2  = J 1 /2. Therefore, for J 2  = J 1 /2, under such parameters, a first-order phase transition between the two states for these two cases below the critical temperatures may occur. When J 2  ≠ J 1 /2, the Néel and collinear states may also exist, while they have different critical temperatures. When J 2  > J 1 /2, a first-order phase transition between the two states may also occur. However, for J 2  J 1 /2, the Néel state is always more stable than the collinear state.

7 CFR 58.144 - Pasteurization or ultra-pasteurization.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Pasteurization or ultra-pasteurization. 58.144 Section... Service 1 Operations and Operating Procedures § 58.144 Pasteurization or ultra-pasteurization. When pasteurization or ultra-pasteurization is intended or required, or when a product is designated “pasteurized” or...

Thermal analysis of injection beam dump of high-intensity rapid-cycling synchrotron in J-PARC

Science.gov (United States)

Kamiya, J.; Saha, P. K.; Yamamoto, K.; Kinsho, M.; Nihei, T.

2017-10-01