WorldWideScience

Sample records for included document analysis

  1. Technical support document: Energy conservation standards for consumer products: Dishwashers, clothes washers, and clothes dryers including: Environmental impacts; regulatory impact analysis

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-01

    The Energy Policy and Conservation Act as amended (P.L. 94-163), establishes energy conservation standards for 12 of the 13 types of consumer products specifically covered by the Act. The legislation requires the Department of Energy (DOE) to consider new or amended standards for these and other types of products at specified times. This Technical Support Document presents the methodology, data and results from the analysis of the energy and economic impacts of standards on dishwashers, clothes washers, and clothes dryers. The economic impact analysis is performed in five major areas: An Engineering Analysis, which establishes technical feasibility and product attributes including costs of design options to improve appliance efficiency. A Consumer Analysis at two levels: national aggregate impacts, and impacts on individuals. The national aggregate impacts include forecasts of appliance sales, efficiencies, energy use, and consumer expenditures. The individual impacts are analyzed by Life-Cycle Cost (LCC), Payback Periods, and Cost of Conserved Energy (CCE), which evaluate the savings in operating expenses relative to increases in purchase price; A Manufacturer Analysis, which provides an estimate of manufacturers' response to the proposed standards. Their response is quantified by changes in several measures of financial performance for a firm. An Industry Impact Analysis shows financial and competitive impacts on the appliance industry. A Utility Analysis that measures the impacts of the altered energy-consumption patterns on electric utilities. A Environmental Effects analysis, which estimates changes in emissions of carbon dioxide, sulfur oxides, and nitrogen oxides, due to reduced energy consumption in the home and at the power plant. A Regulatory Impact Analysis collects the results of all the analyses into the net benefits and costs from a national perspective. 47 figs., 171 tabs. (JF)

  2. Analysis of Design Documentation

    DEFF Research Database (Denmark)

    Hansen, Claus Thorp

    1998-01-01

    has been established where we seek to identify useful design work patterns by retrospective analyses of documentation created during design projects. This paper describes the analysis method, a tentatively defined metric to evaluate identified work patterns, and presents results from the first...... analysis accomplished....

  3. Technical support document: Energy efficiency standards for consumer products: Refrigerators, refrigerator-freezers, and freezers including draft environmental assessment, regulatory impact analysis

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The Energy Policy and Conservation Act (P.L. 94-163), as amended by the National Appliance Energy Conservation Act of 1987 (P.L. 100-12) and by the National Appliance Energy Conservation Amendments of 1988 (P.L. 100-357), and by the Energy Policy Act of 1992 (P.L. 102-486), provides energy conservation standards for 12 of the 13 types of consumer products` covered by the Act, and authorizes the Secretary of Energy to prescribe amended or new energy standards for each type (or class) of covered product. The assessment of the proposed standards for refrigerators, refrigerator-freezers, and freezers presented in this document is designed to evaluate their economic impacts according to the criteria in the Act. It includes an engineering analysis of the cost and performance of design options to improve the efficiency of the products; forecasts of the number and average efficiency of products sold, the amount of energy the products will consume, and their prices and operating expenses; a determination of change in investment, revenues, and costs to manufacturers of the products; a calculation of the costs and benefits to consumers, electric utilities, and the nation as a whole; and an assessment of the environmental impacts of the proposed standards.

  4. Document image analysis: A primer

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    Abstract. Document image analysis refers to algorithms and techniques that are applied to images of documents to obtain a computer-readable description from pixel data. A well-known document image analysis product is the Optical Character. Recognition (OCR) software that recognizes characters in a scanned document ...

  5. Document image analysis: A primer

    Indian Academy of Sciences (India)

    OCR makes it possible for the user to edit or search the document's contents. In this paper we briefly describe various components of a document analysis system. Many of these basic building blocks are found in most document analysis systems, irrespective of the particular domain or language to which they are applied.

  6. Document image analysis: A primer

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    different computers and software such that even their electronic formats are incompatible. Some include both formatted text and tables as ... entries into electronic documents. Archives of paper documents in ..... is very unlikely that qveen would occur in the English language dictionary. Furthermore, one could use knowledge ...

  7. Uruguayan geological documents produced and included in INIS Database- IAEA

    International Nuclear Information System (INIS)

    Rebellato, A.

    2007-01-01

    A possible promotion way for Uruguayan geological documents or foreigner authors who public their researchers in Uruguay was given by International Nuclear Information System INIS of the International Agency Atomic Energy .The article shows not only the INIS historic information, integration products, services and operation but also a safe tool for scientific and technological knowledge preservation. (author)

  8. AVIS: analysis method for document coherence

    International Nuclear Information System (INIS)

    Henry, J.Y.; Elsensohn, O.

    1994-06-01

    The present document intends to give a short insight into AVIS, a method which permits to verify the quality of technical documents. The paper includes the presentation of the applied approach based on the K.O.D. method, the definition of quality criteria of a technical document, as well as a description of the means of valuating these criteria. (authors). 9 refs., 2 figs

  9. Planning, Conducting, and Documenting Data Analysis for Program Improvement

    Science.gov (United States)

    Winer, Abby; Taylor, Cornelia; Derrington, Taletha; Lucas, Anne

    2015-01-01

    This 2015 document was developed to help technical assistance (TA) providers and state staff define and limit the scope of data analysis for program improvement efforts, including the State Systemic Improvement Plan (SSIP); develop a plan for data analysis; document alternative hypotheses and additional analyses as they are generated; and…

  10. Forensic document analysis using scanning microscopy

    Science.gov (United States)

    Shaffer, Douglas K.

    2009-05-01

    The authentication and identification of the source of a printed document(s) can be important in forensic investigations involving a wide range of fraudulent materials, including counterfeit currency, travel and identity documents, business and personal checks, money orders, prescription labels, travelers checks, medical records, financial documents and threatening correspondence. The physical and chemical characterization of document materials - including paper, writing inks and printed media - is becoming increasingly relevant for law enforcement agencies, with the availability of a wide variety of sophisticated commercial printers and copiers which are capable of producing fraudulent documents of extremely high print quality, rendering these difficult to distinguish from genuine documents. This paper describes various applications and analytical methodologies using scanning electron miscoscopy/energy dispersive (x-ray) spectroscopy (SEM/EDS) and related technologies for the characterization of fraudulent documents, and illustrates how their morphological and chemical profiles can be compared to (1) authenticate and (2) link forensic documents with a common source(s) in their production history.

  11. Document analysis with neural net circuits

    Science.gov (United States)

    Graf, Hans Peter

    1994-01-01

    Document analysis is one of the main applications of machine vision today and offers great opportunities for neural net circuits. Despite more and more data processing with computers, the number of paper documents is still increasing rapidly. A fast translation of data from paper into electronic format is needed almost everywhere, and when done manually, this is a time consuming process. Markets range from small scanners for personal use to high-volume document analysis systems, such as address readers for the postal service or check processing systems for banks. A major concern with present systems is the accuracy of the automatic interpretation. Today's algorithms fail miserably when noise is present, when print quality is poor, or when the layout is complex. A common approach to circumvent these problems is to restrict the variations of the documents handled by a system. In our laboratory, we had the best luck with circuits implementing basic functions, such as convolutions, that can be used in many different algorithms. To illustrate the flexibility of this approach, three applications of the NET32K circuit are described in this short viewgraph presentation: locating address blocks, cleaning document images by removing noise, and locating areas of interest in personal checks to improve image compression. Several of the ideas realized in this circuit that were inspired by neural nets, such as analog computation with a low resolution, resulted in a chip that is well suited for real-world document analysis applications and that compares favorably with alternative, 'conventional' circuits.

  12. Cultural diversity: blind spot in medical curriculum documents, a document analysis.

    Science.gov (United States)

    Paternotte, Emma; Fokkema, Joanne P I; van Loon, Karsten A; van Dulmen, Sandra; Scheele, Fedde

    2014-08-22

    Cultural diversity among patients presents specific challenges to physicians. Therefore, cultural diversity training is needed in medical education. In cases where strategic curriculum documents form the basis of medical training it is expected that the topic of cultural diversity is included in these documents, especially if these have been recently updated. The aim of this study was to assess the current formal status of cultural diversity training in the Netherlands, which is a multi-ethnic country with recently updated medical curriculum documents. In February and March 2013, a document analysis was performed of strategic curriculum documents for undergraduate and postgraduate medical education in the Netherlands. All text phrases that referred to cultural diversity were extracted from these documents. Subsequently, these phrases were sorted into objectives, training methods or evaluation tools to assess how they contributed to adequate curriculum design. Of a total of 52 documents, 33 documents contained phrases with information about cultural diversity training. Cultural diversity aspects were more prominently described in the curriculum documents for undergraduate education than in those for postgraduate education. The most specific information about cultural diversity was found in the blueprint for undergraduate medical education. In the postgraduate curriculum documents, attention to cultural diversity differed among specialties and was mainly superficial. Cultural diversity is an underrepresented topic in the Dutch documents that form the basis for actual medical training, although the documents have been updated recently. Attention to the topic is thus unwarranted. This situation does not fit the demand of a multi-ethnic society for doctors with cultural diversity competences. Multi-ethnic countries should be critical on the content of the bases for their medical educational curricula.

  13. Indian Language Document Analysis and Understanding

    Indian Academy of Sciences (India)

    character recognition in different Indian languages, pre- and post-processing techniques tai- lored for Indian languages and user-friendly interfaces for better utilisation of the output of document analysis systems, all need attention from Indian scientists working in Image Pro- cessing and Pattern Recognition. It is with this ...

  14. Technical document characterization by data analysis

    International Nuclear Information System (INIS)

    Mauget, A.

    1993-05-01

    Nuclear power plants possess documents analyzing all the plant systems, which represents a vast quantity of paper. Analysis of textual data can enable a document to be classified by grouping the texts containing the same words. These methods are used on system manuals for feasibility studies. The system manual is then analyzed by LEXTER and the terms it has selected are examined. We first classify according to style (sentences containing general words, technical sentences, etc.), and then according to terms. However, it will not be possible to continue in this fashion for the 100 system manuals existing, because of lack of sufficient storage capacity. Another solution is being developed. (author)

  15. SNF fuel retrieval sub project safety analysis document

    Energy Technology Data Exchange (ETDEWEB)

    BERGMANN, D.W.

    1999-02-24

    This safety analysis is for the SNF Fuel Retrieval (FRS) Sub Project. The FRS equipment will be added to K West and K East Basins to facilitate retrieval, cleaning and repackaging the spent nuclear fuel into Multi-Canister Overpack baskets. The document includes a hazard evaluation, identifies bounding accidents, documents analyses of the accidents and establishes safety class or safety significant equipment to mitigate accidents as needed.

  16. Migration path for structured documentation systems including standardized medical device data.

    Science.gov (United States)

    Kock, Ann-Kristin; Ingenerf, Josef; Halkaliev, Stoyan; Handels, Heinz

    2012-01-01

    A standardized end-to-end solution has been implemented with the aim of supporting the semantic integration of clinical content in institution spanning applications. The approach outlined is a proof-of-concept design. It has shown that the standards chosen are suitable to integrate device data into forms, to document the results consistently and finally enable semantic interoperability. In detail the implementation includes a standardized device interface, a standardized representation of data entry forms and enables the communication of structured data via HL7 CDA. Because the proposed method applies a combination of standards semantic interoperability and the possibility of a contextual interpretation at each stage can be ensured.

  17. Document Analysis Algorithms and Machine Translation Research

    Science.gov (United States)

    Noel, Jacques

    1975-01-01

    Information science has in recent years developed an algorithmic procedure for content analysis of abstracts which includes setting up a metalanguage for a particular field of knowledge. Such a procedure may aid in solving problems of automatic text analysis in machine translation. (TL)

  18. Preliminary Safety Information Document for the Standard MHTGR. Volume 1, (includes latest Amendments)

    Energy Technology Data Exchange (ETDEWEB)

    None

    1986-01-01

    With NRC concurrence, the Licensing Plan for the Standard HTGR describes an application program consistent with 10CFR50, Appendix O to support a US Nuclear Regulatory Commission (NRC) review and design certification of an advanced Standard modular High Temperature Gas-Cooled Reactor (MHTGR) design. Consistent with the NRC's Advanced Reactor Policy, the Plan also outlines a series of preapplication activities which have as an objective the early issuance of an NRC Licensability Statement on the Standard MHTGR conceptual design. This Preliminary Safety Information Document (PSID) has been prepared as one of the submittals to the NRC by the US Department of Energy in support of preapplication activities on the Standard MHTGR. Other submittals to be provided include a Probabilistic Risk Assessment, a Regulatory Technology Development Plan, and an Emergency Planning Bases Report.

  19. The Importance of Documenting and Including Traditional Wisdom in Community-Based Ecotourism Planning

    Directory of Open Access Journals (Sweden)

    Vesna Đukić

    2017-01-01

    Full Text Available This article accords to the theory of community-based tourism, which represents a concept that respects natural and cultural resources of a particular community and encourages participation of its members in the process of tourist product creation. The article operates in the planning phase and aims to give insights into the process of establishing the groundwork for community-based tourism. The key element is documenting and illustrating everything that could be a part of what is known as “traditional wisdom,” namely, the skills and knowledge of traditional life practices. The methods of case study, content analysis, and observation of the village of Omoljica, Serbia, were used. The positive aspect of this locality is reflected in the existing short-term initiatives of organizations and individuals engaging in preserving traditional practices, but without systematic, long-term planning and management of community-based tourism, these individual efforts to revalue traditional life practices would stay unrecognizable and invisible for visitors and stakeholders. Thus, the main goal of this article is to understand the relation between short-term bottom-up initiatives and long-term top-down strategic planning of specific ecotourism destinations, one that would embrace the traditional ways of rural community life. The contribution of this study, in addition to documenting and illustrating “traditional wisdom” of the specific rural community placed in the protected area which encompasses a particular local social system, will be reflected in the creation of a set of guidelines for sustainable, rural, community-based ecotourism as a soft-driver development of protected areas near big cities of the postsocialist countries.

  20. Areva - Updated Reference Document 2015 Including the 2016 half-year financial report

    International Nuclear Information System (INIS)

    2016-01-01

    Areva supplies high added-value products and services to support the operation of the global nuclear fleet. The company is present throughout the entire nuclear cycle, from uranium mining to used fuel recycling, including nuclear reactor design and operating services. Areva is recognized by utilities around the world for its expertise, its skills in cutting-edge technologies and its dedication to the highest level of safety. Areva's 40,000 employees are helping build tomorrow's energy model: supplying ever safer, cleaner and more economical energy to the greatest number of people. This Reference Document contains information on Areva's objectives, prospects and development strategies. It contains estimates of the markets, market shares and competitive position of Areva. Contents: 1 - Persons responsible; 2 - Information on operations and recent events (Overview of the Group's operations, Simplified organization chart of the Group, Implementation of the Group's strategic roadmap and Restructuring Plan, Deployment of the performance plan, Other significant transactions since the filing of the Reference Document, Review of third quarter 2016 operations, Press releases); 3 - Financial information (2016 Half-year financial report, Statutory auditors' report on the half-year financial information for the period January 1 to June 30, 2016, Unaudited consolidated pro-forma financial information, Statutory auditors' report on the pro-forma financial information); 4 - Risk factors (Risks related to the Restructuring Plan, Legal risks, Industrial and environmental risks, Operational risks, Liquidity and market risks); 5 - Cash and capital resources (Financial outlook, 12-month liquidity); 6 - Governance; 7 - Workforce - jobs (Voluntary departure plan and change in the Group's workforce, Signature of a memorandum of understanding ensuring the stability of labor agreements, Reorganization and refinancing of the Group); 8 - Share

  1. Rapid Exploitation and Analysis of Documents

    Energy Technology Data Exchange (ETDEWEB)

    Buttler, D J; Andrzejewski, D; Stevens, K D; Anastasiu, D; Gao, B

    2011-11-28

    Analysts are overwhelmed with information. They have large archives of historical data, both structured and unstructured, and continuous streams of relevant messages and documents that they need to match to current tasks, digest, and incorporate into their analysis. The purpose of the READ project is to develop technologies to make it easier to catalog, classify, and locate relevant information. We approached this task from multiple angles. First, we tackle the issue of processing large quantities of information in reasonable time. Second, we provide mechanisms that allow users to customize their queries based on latent topics exposed from corpus statistics. Third, we assist users in organizing query results, adding localized expert structure over results. Forth, we use word sense disambiguation techniques to increase the precision of matching user generated keyword lists with terms and concepts in the corpus. Fifth, we enhance co-occurrence statistics with latent topic attribution, to aid entity relationship discovery. Finally we quantitatively analyze the quality of three popular latent modeling techniques to examine under which circumstances each is useful.

  2. A Flocking Based algorithm for Document Clustering Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Xiaohui [ORNL; Gao, Jinzhu [ORNL; Potok, Thomas E [ORNL

    2006-01-01

    Social animals or insects in nature often exhibit a form of emergent collective behavior known as flocking. In this paper, we present a novel Flocking based approach for document clustering analysis. Our Flocking clustering algorithm uses stochastic and heuristic principles discovered from observing bird flocks or fish schools. Unlike other partition clustering algorithm such as K-means, the Flocking based algorithm does not require initial partitional seeds. The algorithm generates a clustering of a given set of data through the embedding of the high-dimensional data items on a two-dimensional grid for easy clustering result retrieval and visualization. Inspired by the self-organized behavior of bird flocks, we represent each document object with a flock boid. The simple local rules followed by each flock boid result in the entire document flock generating complex global behaviors, which eventually result in a clustering of the documents. We evaluate the efficiency of our algorithm with both a synthetic dataset and a real document collection that includes 100 news articles collected from the Internet. Our results show that the Flocking clustering algorithm achieves better performance compared to the K- means and the Ant clustering algorithm for real document clustering.

  3. Canister storage building design basis accident analysis documentation

    International Nuclear Information System (INIS)

    KOPELIC, S.D.

    1999-01-01

    This document provides the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report

  4. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    International Nuclear Information System (INIS)

    CROWE, R.D.

    1999-01-01

    This document provides the detailed accident analysis to support ''HNF-3553, Spent Nuclear Fuel Project Final Safety, Analysis Report, Annex A,'' ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report

  5. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    International Nuclear Information System (INIS)

    CROWE, R.D.; PIEPHO, M.G.

    2000-01-01

    This document provided the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report''. All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report

  6. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    Energy Technology Data Exchange (ETDEWEB)

    CROWE, R.D.; PIEPHO, M.G.

    2000-03-23

    This document provided the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report''. All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report.

  7. Canister storage building design basis accident analysis documentation

    Energy Technology Data Exchange (ETDEWEB)

    KOPELIC, S.D.

    1999-02-25

    This document provides the detailed accident analysis to support HNF-3553, Spent Nuclear Fuel Project Final Safety Analysis Report, Annex A, ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report.

  8. ETM documentation update – including modelling conventions and manual for software tools

    DEFF Research Database (Denmark)

    Grohnheit, Poul Erik

    , it summarises the work done during 2013, and it also contains presentations for promotion of fusion as a future element in the electricity generation mix and presentations for the modelling community concerning model development and model documentation – in particular for TIAM collaboration workshops....

  9. Indian Language Document Analysis and Understanding

    Indian Academy of Sciences (India)

    authoritative manner outlining all the issues involved. The next two papers deal with com- plete systems designed for processing printed text documents in a single language. The paper by Chaudhuri, Pal and Mitra, which is also an invited contribution, describes a system for recognition of printed Oriya script. The paper by ...

  10. Cold Vacuum Drying Facility Design Basis Accident Analysis Documentation

    International Nuclear Information System (INIS)

    PIEPHO, M.G.

    1999-01-01

    This document provides the detailed accident analysis to support HNF-3553, Annex B, Spent Nuclear Fuel Project Final Safety Analysis Report, ''Cold Vacuum Drying Facility Final Safety Analysis Report (FSAR).'' All assumptions, parameters and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the FSAR

  11. FY 2016 Status Report: Documentation of All CIRFT Data including Hydride Reorientation Tests (Draft M2)

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jy-An John [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Wang, Hong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Jiang, Hao [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Yan, Yong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Bevard, Bruce B. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division; Scaglione, John M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Materials Science and Technology Division

    2016-09-04

    The first portion of this report provides a detailed description of fiscal year (FY) 2015 test result corrections and analysis updates based on FY 2016 updates to the Cyclic Integrated Reversible-Bending Fatigue Tester (CIRFT) program methodology, which is used to evaluate the vibration integrity of spent nuclear fuel (SNF) under normal conditions of transport (NCT). The CIRFT consists of a U-frame test setup and a real-time curvature measurement method. The three-component U-frame setup of the CIRFT has two rigid arms and linkages connecting to a universal testing machine. The curvature SNF rod bending is obtained through a three-point deflection measurement method. Three linear variable differential transformers (LVDTs) are clamped to the side connecting plates of the U-frame and used to capture deformation of the rod. The second portion of this report provides the latest CIRFT data, including data for the hydride reorientation test. The variations in fatigue life are provided in terms of moment, equivalent stress, curvature, and equivalent strain for the tested SNFs. The equivalent stress plot collapsed the data points from all of the SNF samples into a single zone. A detailed examination revealed that, at the same stress level, fatigue lives display a descending order as follows: H. B. Robinson Nuclear Power Station (HBR), LMK, and mixed uranium-plutonium oxide (MOX). Just looking at the strain, LMK fuel has a slightly longer fatigue life than HBR fuel, but the difference is subtle. The third portion of this report provides finite element analysis (FEA) dynamic deformation simulation of SNF assemblies . In a horizontal layout under NCT, the fuel assembly’s skeleton, which is formed by guide tubes and spacer grids, is the primary load bearing apparatus carrying and transferring vibration loads within an SNF assembly. These vibration loads include interaction forces between the SNF assembly and the canister basket walls. Therefore, the integrity of the guide

  12. 10 CFR 1021.330 - Programmatic (including site-wide) NEPA documents.

    Science.gov (United States)

    2010-01-01

    ... supporting analysis shall be made available in the appropriate DOE public reading room(s) or in other... site-wide EISs by means of a Supplement Analysis, as provided in § 1021.314. Based on the Supplement Analysis, DOE shall determine whether the existing EIS remains adequate or whether to prepare a new site...

  13. Canister Storage Building (CSB) Design Basis Accident Analysis Documentation

    Energy Technology Data Exchange (ETDEWEB)

    CROWE, R.D.

    1999-09-09

    This document provides the detailed accident analysis to support ''HNF-3553, Spent Nuclear Fuel Project Final Safety, Analysis Report, Annex A,'' ''Canister Storage Building Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the Canister Storage Building Final Safety Analysis Report.

  14. DNA Analysis and Document Examination: The Impact of Each Technique on Respective Analyses.

    Science.gov (United States)

    Parsons, Lauren; Sharfe, Gordon; Vintiner, Sue

    2016-01-01

    Threatening letters, counterfeit documents, and anonymous notes can commonly be encountered in criminal situations. Such handwritten documents may encourage DNA to transfer from the writer's hands and lower arms when these areas come into contact with the document. As any DNA transferred is likely to be at a low level, sensitive low copy number (LCN) DNA analysis can be employed for testing document exhibits. In this study, we determine locations on the document that are most commonly touched during writing and handling and compare DNA recovery from these sites. We describe the impact of DNA sampling on subsequent document examination techniques including the ESDA(®) and likewise the effect of the ESDA(®) and two other document examination techniques on subsequent DNA analysis. The findings from this study suggest that DNA results can be obtained through targeted sampling of document evidence, but that care is required when ordering these examination strategies. © 2015 American Academy of Forensic Sciences.

  15. Spectrum analysis on quality requirements consideration in software design documents.

    Science.gov (United States)

    Kaiya, Haruhiko; Umemura, Masahiro; Ogata, Shinpei; Kaijiri, Kenji

    2013-12-01

    Software quality requirements defined in the requirements analysis stage should be implemented in the final products, such as source codes and system deployment. To guarantee this meta-requirement, quality requirements should be considered in the intermediate stages, such as the design stage or the architectural definition stage. We propose a novel method for checking whether quality requirements are considered in the design stage. In this method, a technique called "spectrum analysis for quality requirements" is applied not only to requirements specifications but also to design documents. The technique enables us to derive the spectrum of a document, and quality requirements considerations in the document are numerically represented in the spectrum. We can thus objectively identify whether the considerations of quality requirements in a requirements document are adapted to its design document. To validate the method, we applied it to commercial software systems with the help of a supporting tool, and we confirmed that the method worked well.

  16. Developing Methods of praxeology to Perform Document-analysis

    DEFF Research Database (Denmark)

    Frederiksen, Jesper

    2016-01-01

    This paper provides a contribution to the methodological development on praxeologic document analysis of neoliberal welfare state policies. Different institutions related to the Danish Healthcare area, transform international health policies and these institutions produce a range of strategies. T...

  17. Planning Document for an NBSR Conversion Safety Analysis Report

    Energy Technology Data Exchange (ETDEWEB)

    Diamond D. J.; Baek J.; Hanson, A.L.; Cheng, L-Y.; Brown, N.; Cuadra, A.

    2013-09-25

    The NIST Center for Neutron Research (NCNR) is a reactor-laboratory complex providing the National Institute of Standards and Technology (NIST) and the nation with a world-class facility for the performance of neutron-based research. The heart of this facility is the National Bureau of Standards Reactor (NBSR). The NBSR is a heavy water moderated and cooled reactor operating at 20 MW. It is fueled with high-enriched uranium (HEU) fuel elements. A Global Threat Reduction Initiative (GTRI) program is underway to convert the reactor to low-enriched uranium (LEU) fuel. This program includes the qualification of the proposed fuel, uranium and molybdenum alloy foil clad in an aluminum alloy, and the development of the fabrication techniques. This report is a planning document for the conversion Safety Analysis Report (SAR) that would be submitted to, and approved by, the Nuclear Regulatory Commission (NRC) before the reactor could be converted.This report follows the recommended format and content from the NRC codified in NUREG-1537, “Guidelines for Preparing and Reviewing Applications for the Licensing of Non-power Reactors,” Chapter 18, “Highly Enriched to Low-Enriched Uranium Conversions.” The emphasis herein is on the SAR chapters that require significant changes as a result of conversion, primarily Chapter 4, Reactor Description, and Chapter 13, Safety Analysis. The document provides information on the proposed design for the LEU fuel elements and identifies what information is still missing. This document is intended to assist ongoing fuel development efforts, and to provide a platform for the development of the final conversion SAR. This report contributes directly to the reactor conversion pillar of the GTRI program, but also acts as a boundary condition for the fuel development and fuel fabrication pillars.

  18. A Conceptual Model for Multidimensional Analysis of Documents

    Science.gov (United States)

    Ravat, Franck; Teste, Olivier; Tournier, Ronan; Zurlfluh, Gilles

    Data warehousing and OLAP are mainly used for the analysis of transactional data. Nowadays, with the evolution of Internet, and the development of semi-structured data exchange format (such as XML), it is possible to consider entire fragments of data such as documents as analysis sources. As a consequence, an adapted multidimensional analysis framework needs to be provided. In this paper, we introduce an OLAP multidimensional conceptual model without facts. This model is based on the unique concept of dimensions and is adapted for multidimensional document analysis. We also provide a set of manipulation operations.

  19. Security analysis for biometric data in ID documents

    Science.gov (United States)

    Schimke, Sascha; Kiltz, Stefan; Vielhauer, Claus; Kalker, Ton

    2005-03-01

    In this paper we analyze chances and challenges with respect to the security of using biometrics in ID documents. We identify goals for ID documents, set by national and international authorities, and discuss the degree of security, which is obtainable with the inclusion of biometric into documents like passports. Starting from classical techniques for manual authentication of ID card holders, we expand our view towards automatic methods based on biometrics. We do so by reviewing different human biometric attributes by modality, as well as by discussing possible techniques for storing and handling the particular biometric data on the document. Further, we explore possible vulnerabilities of potential biometric passport systems. Based on the findings of that discussion we will expand upon two exemplary approaches for including digital biometric data in the context of ID documents and present potential risks attack scenarios along with technical aspects such as capacity and robustness.

  20. Technical requirements document for the waste flow analysis

    International Nuclear Information System (INIS)

    Shropshire, D.E.

    1996-05-01

    Purpose of this Technical Requirements Document is to define the top level customer requirements for the Waste Flow Analysis task. These requirements, once agreed upon with DOE, will be used to flow down subsequent development requirements to the model specifications. This document is intended to be a ''living document'' which will be modified over the course of the execution of this work element. Initial concurrence with the technical functional requirements from Environmental Management (EM)-50 is needed before the work plan can be developed

  1. Developing Methods of praxeology to Perform Document-analysis

    DEFF Research Database (Denmark)

    Frederiksen, Jesper

    2016-01-01

    . The affiliations of the different institutional and professional logics affect the strategies. Based on three empirical studies from welfare state documents of Inter-professional collaboration, Coherence in healthcare and Patient-safety by incident report, a summative description on the methodological work......This paper provides a contribution to the methodological development on praxeologic document analysis of neoliberal welfare state policies. Different institutions related to the Danish Healthcare area, transform international health policies and these institutions produce a range of strategies...

  2. Simplifying documentation while approaching site closure: integrated health and safety plans as documented safety analysis

    International Nuclear Information System (INIS)

    Brown, Tulanda

    2003-01-01

    At the Fernald Closure Project (FCP) near Cincinnati, Ohio, environmental restoration activities are supported by Documented Safety Analyses (DSAs) that combine the required project-specific Health and Safety Plans, Safety Basis Requirements (SBRs), and Process Requirements (PRs) into single Integrated Health and Safety Plans (I-HASPs). By isolating any remediation activities that deal with Enriched Restricted Materials, the SBRs and PRs assure that the hazard categories of former nuclear facilities undergoing remediation remain less than Nuclear. These integrated DSAs employ Integrated Safety Management methodology in support of simplified restoration and remediation activities that, so far, have resulted in the decontamination and demolition (D and D) of over 150 structures, including six major nuclear production plants. This paper presents the FCP method for maintaining safety basis documentation, using the D and D I-HASP as an example

  3. Documented Safety Analysis for the B695 Segment

    International Nuclear Information System (INIS)

    Laycak, D.

    2008-01-01

    This Documented Safety Analysis (DSA) was prepared for the Lawrence Livermore National Laboratory (LLNL) Building 695 (B695) Segment of the Decontamination and Waste Treatment Facility (DWTF). The report provides comprehensive information on design and operations, including safety programs and safety structures, systems and components to address the potential process-related hazards, natural phenomena, and external hazards that can affect the public, facility workers, and the environment. Consideration is given to all modes of operation, including the potential for both equipment failure and human error. The facilities known collectively as the DWTF are used by LLNL's Radioactive and Hazardous Waste Management (RHWM) Division to store and treat regulated wastes generated at LLNL. RHWM generally processes low-level radioactive waste with no, or extremely low, concentrations of transuranics (e.g., much less than 100 nCi/g). Wastes processed often contain only depleted uranium and beta- and gamma-emitting nuclides, e.g., 90 Sr, 137 Cs, or 3 H. The mission of the B695 Segment centers on container storage, lab-packing, repacking, overpacking, bulking, sampling, waste transfer, and waste treatment. The B695 Segment is used for storage of radioactive waste (including transuranic and low-level), hazardous, nonhazardous, mixed, and other waste. Storage of hazardous and mixed waste in B695 Segment facilities is in compliance with the Resource Conservation and Recovery Act (RCRA). LLNL is operated by the Lawrence Livermore National Security, LLC, for the Department of Energy (DOE). The B695 Segment is operated by the RHWM Division of LLNL. Many operations in the B695 Segment are performed under a Resource Conservation and Recovery Act (RCRA) operation plan, similar to commercial treatment operations with best demonstrated available technologies. The buildings of the B695 Segment were designed and built considering such operations, using proven building systems, and keeping

  4. Documented Safety Analysis for the B695 Segment

    Energy Technology Data Exchange (ETDEWEB)

    Laycak, D

    2008-09-11

    This Documented Safety Analysis (DSA) was prepared for the Lawrence Livermore National Laboratory (LLNL) Building 695 (B695) Segment of the Decontamination and Waste Treatment Facility (DWTF). The report provides comprehensive information on design and operations, including safety programs and safety structures, systems and components to address the potential process-related hazards, natural phenomena, and external hazards that can affect the public, facility workers, and the environment. Consideration is given to all modes of operation, including the potential for both equipment failure and human error. The facilities known collectively as the DWTF are used by LLNL's Radioactive and Hazardous Waste Management (RHWM) Division to store and treat regulated wastes generated at LLNL. RHWM generally processes low-level radioactive waste with no, or extremely low, concentrations of transuranics (e.g., much less than 100 nCi/g). Wastes processed often contain only depleted uranium and beta- and gamma-emitting nuclides, e.g., {sup 90}Sr, {sup 137}Cs, or {sup 3}H. The mission of the B695 Segment centers on container storage, lab-packing, repacking, overpacking, bulking, sampling, waste transfer, and waste treatment. The B695 Segment is used for storage of radioactive waste (including transuranic and low-level), hazardous, nonhazardous, mixed, and other waste. Storage of hazardous and mixed waste in B695 Segment facilities is in compliance with the Resource Conservation and Recovery Act (RCRA). LLNL is operated by the Lawrence Livermore National Security, LLC, for the Department of Energy (DOE). The B695 Segment is operated by the RHWM Division of LLNL. Many operations in the B695 Segment are performed under a Resource Conservation and Recovery Act (RCRA) operation plan, similar to commercial treatment operations with best demonstrated available technologies. The buildings of the B695 Segment were designed and built considering such operations, using proven building

  5. Delve: A Data Set Retrieval and Document Analysis System

    KAUST Repository

    Akujuobi, Uchenna Thankgod

    2017-12-29

    Academic search engines (e.g., Google scholar or Microsoft academic) provide a medium for retrieving various information on scholarly documents. However, most of these popular scholarly search engines overlook the area of data set retrieval, which should provide information on relevant data sets used for academic research. Due to the increasing volume of publications, it has become a challenging task to locate suitable data sets on a particular research area for benchmarking or evaluations. We propose Delve, a web-based system for data set retrieval and document analysis. This system is different from other scholarly search engines as it provides a medium for both data set retrieval and real time visual exploration and analysis of data sets and documents.

  6. 32 CFR 775.9 - Documentation and analysis.

    Science.gov (United States)

    2010-07-01

    ... analyses is: (i) From a broad program, plan, or policy environmental impact statement (not necessarily site... tier itself may have a significant impact on the quality of the human environment or when an impact... FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT § 775.9 Documentation and analysis. (a...

  7. Cold Vacuum Drying facility design basis accident analysis documentation

    Energy Technology Data Exchange (ETDEWEB)

    CROWE, R.D.

    2000-08-08

    This document provides the detailed accident analysis to support HNF-3553, Annex B, Spent Nuclear Fuel Project Final Safety Analysis Report (FSAR), ''Cold Vacuum Drying Facility Final Safety Analysis Report.'' All assumptions, parameters, and models used to provide the analysis of the design basis accidents are documented to support the conclusions in the FSAR. The calculations in this document address the design basis accidents (DBAs) selected for analysis in HNF-3553, ''Spent Nuclear Fuel Project Final Safety Analysis Report'', Annex B, ''Cold Vacuum Drying Facility Final Safety Analysis Report.'' The objective is to determine the quantity of radioactive particulate available for release at any point during processing at the Cold Vacuum Drying Facility (CVDF) and to use that quantity to determine the amount of radioactive material released during the DBAs. The radioactive material released is used to determine dose consequences to receptors at four locations, and the dose consequences are compared with the appropriate evaluation guidelines and release limits to ascertain the need for preventive and mitigative controls.

  8. Investigating scientific literacy documents with linguistic network analysis

    DEFF Research Database (Denmark)

    Bruun, Jesper; Evans, Robert Harry; Dolin, Jens

    2009-01-01

    International discussions of scientific literacy (SL) are extensive and numerous sizeable documents on SL exist. Thus, comparing different conceptions of SL is methodologically challenging. We developed an analytical tool which couples the theory of complex networks with text analysis in order...... on the network data. For example a minimal description length approach partitioned the network in to groups of words, which was then seen to represent different visions appearing in the discussion of SL. In short, the networks allow for quantitative analyses as well as a quick visual overview of SL documents....

  9. Documentation and analysis for packaging limited quantity ice chests

    International Nuclear Information System (INIS)

    Nguyen, P.M.

    1995-01-01

    The purpose of this Documentation and Analysis for Packaging (DAP) is to document that ice chests meet the intent of the International Air Transport Association (IATA) and the U.S. Department of Transportation (DOT) Code of Federal Regulations as strong, tight containers for the packaging of limited quantities for transport. This DAP also outlines the packaging method used to protect the sample bottles from breakage. Because the ice chests meet the DOT requirements, they can be used to ship LTD QTY on the Hanford Site

  10. Documented Safety Analysis for the Waste Storage Facilities March 2010

    Energy Technology Data Exchange (ETDEWEB)

    Laycak, D T

    2010-03-05

    This Documented Safety Analysis (DSA) for the Waste Storage Facilities was developed in accordance with 10 CFR 830, Subpart B, 'Safety Basis Requirements,' and utilizes the methodology outlined in DOE-STD-3009-94, Change Notice 3. The Waste Storage Facilities consist of Area 625 (A625) and the Decontamination and Waste Treatment Facility (DWTF) Storage Area portion of the DWTF complex. These two areas are combined into a single DSA, as their functions as storage for radioactive and hazardous waste are essentially identical. The B695 Segment of DWTF is addressed under a separate DSA. This DSA provides a description of the Waste Storage Facilities and the operations conducted therein; identification of hazards; analyses of the hazards, including inventories, bounding releases, consequences, and conclusions; and programmatic elements that describe the current capacity for safe operations. The mission of the Waste Storage Facilities is to safely handle, store, and treat hazardous waste, transuranic (TRU) waste, low-level waste (LLW), mixed waste, combined waste, nonhazardous industrial waste, and conditionally accepted waste generated at LLNL (as well as small amounts from other DOE facilities).

  11. Documented Safety Analysis for the Waste Storage Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Laycak, D

    2008-06-16

    This documented safety analysis (DSA) for the Waste Storage Facilities was developed in accordance with 10 CFR 830, Subpart B, 'Safety Basis Requirements', and utilizes the methodology outlined in DOE-STD-3009-94, Change Notice 3. The Waste Storage Facilities consist of Area 625 (A625) and the Decontamination and Waste Treatment Facility (DWTF) Storage Area portion of the DWTF complex. These two areas are combined into a single DSA, as their functions as storage for radioactive and hazardous waste are essentially identical. The B695 Segment of DWTF is addressed under a separate DSA. This DSA provides a description of the Waste Storage Facilities and the operations conducted therein; identification of hazards; analyses of the hazards, including inventories, bounding releases, consequences, and conclusions; and programmatic elements that describe the current capacity for safe operations. The mission of the Waste Storage Facilities is to safely handle, store, and treat hazardous waste, transuranic (TRU) waste, low-level waste (LLW), mixed waste, combined waste, nonhazardous industrial waste, and conditionally accepted waste generated at LLNL (as well as small amounts from other DOE facilities).

  12. Advances in oriental document analysis and recognition techniques

    CERN Document Server

    Lee, Seong-Whan

    1999-01-01

    In recent years, rapid progress has been made in computer processing of oriental languages, and the research developments in this area have resulted in tremendous changes in handwriting processing, printed oriental character recognition, document analysis and recognition, automatic input methodologies for oriental languages, etc. Advances in computer processing of oriental languages can also be seen in multimedia computing and the World Wide Web. Many of the results in those domains are presented in this book.

  13. Evidence of addiction by anesthesiologists as documented by hair analysis.

    Science.gov (United States)

    Kintz, P; Villain, M; Dumestre, V; Cirimele, V

    2005-10-04

    Chemical dependency is a disease that can affect all professions. Among the health care professionals, anesthesiologists represent a specific group. Numerous factors have been proposed to explain the high incidence of drug abuse among anesthesiologists. These include: easy access to potent drugs, particularly narcotics, highly addictive potential of agents with which they are in contact, and easy diversion of these agents since only small doses will initially provide an effect desired by the abuser. Opioids are the drugs of choice for anesthesiologists, and among them fentanyl and sufentanil are the most commonly used. Alcohol is mostly abused by older anesthesiologists. Propofol, ketamine, thiopental and midazolam are also abused. In fact, all but quaternary ammonium drugs can be observed. Signs and symptoms of addiction in the hospital workplace include: unusual changes in behavior, desire to work alone, refusal of lunch relief or breaks, volunteer for extra cases, call, come in early and leave late, frequent restroom breaks, weight loss and pale skin, malpractice, behind on charts .... Toxicological investigations are difficult, as the drugs of interest are difficult to test for. In most cases, half-lives of the compounds are short, and the circulating concentrations weak. It is, therefore, necessary to develop tandem mass spectrometry procedures to satisfy the criteria of identification and quantitation. In most cases, blood and/or urine analyses are not useful to document impairment, as these specimens are collected at inadequate moments. Hair analysis appears, therefore, as the unique choice to evidence chronic exposure. Depending the length of the hair shaft, it is possible to establish an historical record, associated to the pattern of drug use, considering a growth rate of about 1cm/month. An original procedure was developed to test for fentanyl derivatives. After decontamination with methylene chloride, drugs are extracted from the hair by liquid

  14. Organ donation in the ICU: A document analysis of institutional policies, protocols, and order sets.

    Science.gov (United States)

    Oczkowski, Simon J W; Centofanti, John E; Durepos, Pamela; Arseneau, Erika; Kelecevic, Julija; Cook, Deborah J; Meade, Maureen O

    2018-04-01

    To better understand how local policies influence organ donation rates. We conducted a document analysis of our ICU organ donation policies, protocols and order sets. We used a systematic search of our institution's policy library to identify documents related to organ donation. We used Mindnode software to create a publication timeline, basic statistics to describe document characteristics, and qualitative content analysis to extract document themes. Documents were retrieved from Hamilton Health Sciences, an academic hospital system with a high volume of organ donation, from database inception to October 2015. We retrieved 12 active organ donation documents, including six protocols, two policies, two order sets, and two unclassified documents, a majority (75%) after the introduction of donation after circulatory death in 2006. Four major themes emerged: organ donation process, quality of care, patient and family-centred care, and the role of the institution. These themes indicate areas where documented institutional standards may be beneficial. Further research is necessary to determine the relationship of local policies, protocols, and order sets to actual organ donation practices, and to identify barriers and facilitators to improving donation rates. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Document co-citation analysis to enhance transdisciplinary research.

    Science.gov (United States)

    Trujillo, Caleb M; Long, Tammy M

    2018-01-01

    Specialized and emerging fields of research infrequently cross disciplinary boundaries and would benefit from frameworks, methods, and materials informed by other fields. Document co-citation analysis, a method developed by bibliometric research, is demonstrated as a way to help identify key literature for cross-disciplinary ideas. To illustrate the method in a useful context, we mapped peer-recognized scholarship related to systems thinking. In addition, three procedures for validation of co-citation networks are proposed and implemented. This method may be useful for strategically selecting information that can build consilience about ideas and constructs that are relevant across a range of disciplines.

  16. Document co-citation analysis to enhance transdisciplinary research

    Science.gov (United States)

    Trujillo, Caleb M.; Long, Tammy M.

    2018-01-01

    Specialized and emerging fields of research infrequently cross disciplinary boundaries and would benefit from frameworks, methods, and materials informed by other fields. Document co-citation analysis, a method developed by bibliometric research, is demonstrated as a way to help identify key literature for cross-disciplinary ideas. To illustrate the method in a useful context, we mapped peer-recognized scholarship related to systems thinking. In addition, three procedures for validation of co-citation networks are proposed and implemented. This method may be useful for strategically selecting information that can build consilience about ideas and constructs that are relevant across a range of disciplines. PMID:29308433

  17. Every document and picture tells a story: using internal corporate document reviews, semiotics, and content analysis to assess tobacco advertising.

    Science.gov (United States)

    Anderson, S J; Dewhirst, T; Ling, P M

    2006-06-01

    In this article we present communication theory as a conceptual framework for conducting documents research on tobacco advertising strategies, and we discuss two methods for analysing advertisements: semiotics and content analysis. We provide concrete examples of how we have used tobacco industry documents archives and tobacco advertisement collections iteratively in our research to yield a synergistic analysis of these two complementary data sources. Tobacco promotion researchers should consider adopting these theoretical and methodological approaches.

  18. Near infrared hyperspectral imaging for forensic analysis of document forgery.

    Science.gov (United States)

    Silva, Carolina S; Pimentel, Maria Fernanda; Honorato, Ricardo S; Pasquini, Celio; Prats-Montalbán, José M; Ferrer, Alberto

    2014-10-21

    Hyperspectral images in the near infrared range (HSI-NIR) were evaluated as a nondestructive method to detect fraud in documents. Three different types of typical forgeries were simulated by (a) obliterating text, (b) adding text and (c) approaching the crossing lines problem. The simulated samples were imaged in the range of 928-2524 nm with spectral and spatial resolutions of 6.3 nm and 10 μm, respectively. After data pre-processing, different chemometric techniques were evaluated for each type of forgery. Principal component analysis (PCA) was performed to elucidate the first two types of adulteration, (a) and (b). Moreover, Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) was used in an attempt to improve the results of the type (a) obliteration and type (b) adding text problems. Finally, MCR-ALS and Partial Least Squares-Discriminant Analysis (PLS-DA), employed as a variable selection tool, were used to study the type (c) forgeries, i.e. crossing lines problem. Type (a) forgeries (obliterating text) were successfully identified in 43% of the samples using both the chemometric methods (PCA and MCR-ALS). Type (b) forgeries (adding text) were successfully identified in 82% of the samples using both the methods (PCA and MCR-ALS). Finally, type (c) forgeries (crossing lines) were successfully identified in 85% of the samples. The results demonstrate the potential of HSI-NIR associated with chemometric tools to support document forgery identification.

  19. ENDF/B-5 Standards Data Library (including modifications made in 1986). Summary of contents and documentation

    International Nuclear Information System (INIS)

    DayDay, N.; Lemmel, H.D.

    1986-01-01

    This document summarizes the contents and documentation of the ENDF/B-5 Standards Data Library (EN5-ST) released in September 1979. The library contains complete evaluations for all significant neutron reactions in the energy range 10 -5 eV to 20 MeV for H-1, He-3, Li-6, B-10, C-12, Au-197 and U-235 isotopes. In 1986 the files for C-12, Au-197 and U-235 were slightly modified. The entire library or selective retrievals from it can be obtained free of charge from the IAEA Nuclear Data Section. (author)

  20. EFF-2.4. The European Fusion File, 1994 including revisions up to May 1995. Summary documentation

    International Nuclear Information System (INIS)

    Lemmel, H.D.

    1995-01-01

    A summary documentation of EFF-2.4, the European evaluated neutron nuclear data library for selected materials needed in fusion applications, is given. The data library is available from the IAEA Nuclear Data Section on magnetic tape, costfree upon request, or online from the NEA Data Bank. (author)

  1. Documentation of SPECTROM-55: A finite element thermohydrogeological analysis program

    International Nuclear Information System (INIS)

    Osnes, J.D.; Ratigan, J.L.; Loken, M.C.; Parrish, D.K.

    1985-12-01

    SPECTROM-55 is a finite element computer program developed by RE/SPEC Inc. for analyses of coupled heat and fluid transfer through fully saturated porous media. The theoretical basis for the mathematical model, the implementation of the mathematical model into the computer code, the verification and validation efforts with the computer code, and the code support and continuing documentation are described in this document. The program is especially suited for analyses of the regional hydrogeology in the vicinity of a heat-generating nuclear waste repository. These applications typically involve forced and free convection in a ground-water flow system. The program provides transient or steady-state temperatures, pressures, and fluid velocities resulting from the application of a variety of initial and boundary conditions to bodies with complicated shapes. The boundary conditions include constant heat and fluid fluxes, convective heat transfer, constant temperature, and constant pressure. Initial temperatures and pressures can be specified. Composite systems of anisotropic materials, such as geologic strata, can be defined in either planar or axisymmetric configurations. Constant or varying volumetric heat generation, such as decaying heat generation from radioactive waste, can be specified

  2. Documentation of SPECTROM-55: A finite element thermohydrogeological analysis program

    International Nuclear Information System (INIS)

    Osnes, J.D.; Ratigan, J.L.; Loken, M.C.; Parrish, D.K.

    1989-01-01

    SPECTROM-55 is a finite element computer program for analyses of coupled heat and fluid transfer through fully saturated porous media. The code is part of the SPECTROM (Special Purpose Engineering Codes for Thermal/ROck Mechanics) series of special purpose finite element programs, that address the many unique rock mechanics problems resulting from storage of radioactive waste in geologic formations. This document presents the theoretical basis for the mathematical model, the finite element formulation of the problem, and a description of the input data for the program along with details about program support and continuing documentation. The program is especially suited for analyses of the regional hydrogeology in the vicinity of a heat-generating nuclear waste repository. These applications typically involved forced and free convection in a ground-water flow system. The program provides transient or steady-state temperatures, pressures, and fluid velocities resulting from the application of a variety of initial and boundary conditions to bodies with complicated shapes. The boundary conditions include constant heat and fluid fluxes, convective heat transfer, constant temperature, and constant pressure. Initial temperatures and pressures can be specified. Composite systems of anisotropic materials, such as geologic strata, can be defined in either planar or axisymmetric configurations. Constant or varying volumetric heat generation, such as decaying heat generation from radioactive waste, can be specified

  3. Investigating scientific literacy documents with linguistic network analysis

    DEFF Research Database (Denmark)

    Bruun, Jesper; Evans, Robert Harry; Dolin, Jens

    2009-01-01

    in the one statement sentences. Using the program Pajek, we drew a map of the text showing the number of times a concept appeared in the one statement sentences, and the strength of links between words. Different SL texts was analysed in this way. The network description allowed for different calculations......International discussions of scientific literacy (SL) are extensive and numerous sizeable documents on SL exist. Thus, comparing different conceptions of SL is methodologically challenging. We developed an analytical tool which couples the theory of complex networks with text analysis in order...... to obtain clear visual images of what is meant by SL expressed in written text. The raw text was first parsed into one statement sentences. Then, a linguistic type network was created with nodes being the words used in SL texts, and a link between two words established if they were adjacent to each other...

  4. Document boundary determination using structural and lexical analysis

    Science.gov (United States)

    Taghva, Kazem; Cartright, Marc-Allen

    2009-01-01

    The document boundary determination problem is the process of identifying individual documents in a stack of papers. In this paper, we report on a classification system for automation of this process. The system employs features based on document structure and lexical content. We also report on experimental results to support the effectiveness of this system.

  5. Why include phenomenological analysis in a Research Methods course?

    Science.gov (United States)

    Delgado, Ana R

    2013-01-01

    Guidelines for Spanish university curricula include the descriptor Quantitative and Qualitative Methods, but the latter are still poorly represented. To inform the argument for phenomenological methods, the last 20-year interval of ISI databases has been content-analyzed with the following codes: discourse analysis, grounded theory, narrative analysis, phenomenological analysis and confirmatory factor analysis, that is, four qualitative methods and a prototypical quantitative one. In absolute terms, the most frequent qualitative method is grounded theory, followed by discourse analysis, phenomenological analysis and narrative analysis. However, taking into account content categories, only phenomenological analysis shows a clear psychological profile, similar to confirmatory factor analysis. We recommend starting qualitative training with a method that does not require either big groups, or big funding, and that has a procedural core that is simple, relatively well-delimited and "secularizable," a variety of thematic analysis. Historical reasons and the clear psychological profile evidenced by our results enhance our argument to foster the inclusion of phenomenological analysis in research method courses in psychology.

  6. Critical discourse analysis of social justice in nursing's foundational documents.

    Science.gov (United States)

    Valderama-Wallace, Claire P

    2017-07-01

    Social inequities threaten the health of the global population. A superficial acknowledgement of social justice by nursing's foundational documents may limit the degree to which nurses view injustice as relevant to nursing practice and education. The purpose was to examine conceptualizations of social justice and connections to broader contexts in the most recent editions. Critical discourse analysis examines and uncovers dynamics related to power, language, and inequality within the American Nurses Association's Code of Ethics, Scope and Standards of Practice, and Social Policy Statement. This analysis found ongoing inconsistencies in conceptualizations of social justice. Although the Code of Ethics integrates concepts related to social justice far more than the other two, tension between professionalism and social change emerges. The discourse of professionalism renders interrelated cultural, social, economic, historical, and political contexts nearly invisible. Greater consistency would provide a clearer path for nurses to mobilize and engage in the courageous work necessary to address social injustice. These findings also call for an examination of how nurses can critique and use the power and privilege of professionalism to amplify the connection between social institutions and health equity in nursing education, practice, and policy development. © 2017 Wiley Periodicals, Inc.

  7. Analysis and classification of oncology activities on the way to workflow based single source documentation in clinical information systems.

    Science.gov (United States)

    Wagner, Stefan; Beckmann, Matthias W; Wullich, Bernd; Seggewies, Christof; Ries, Markus; Bürkle, Thomas; Prokosch, Hans-Ulrich

    2015-12-22

    Today, cancer documentation is still a tedious task involving many different information systems even within a single institution and it is rarely supported by appropriate documentation workflows. In a comprehensive 14 step analysis we compiled diagnostic and therapeutic pathways for 13 cancer entities using a mixed approach of document analysis, workflow analysis, expert interviews, workflow modelling and feedback loops. These pathways were stepwise classified and categorized to create a final set of grouped pathways and workflows including electronic documentation forms. A total of 73 workflows for the 13 entities based on 82 paper documentation forms additionally to computer based documentation systems were compiled in a 724 page document comprising 130 figures, 94 tables and 23 tumour classifications as well as 12 follow-up tables. Stepwise classification made it possible to derive grouped diagnostic and therapeutic pathways for the three major classes - solid entities with surgical therapy - solid entities with surgical and additional therapeutic activities and - non-solid entities. For these classes it was possible to deduct common documentation workflows to support workflow-guided single-source documentation. Clinical documentation activities within a Comprehensive Cancer Center can likely be realized in a set of three documentation workflows with conditional branching in a modern workflow supporting clinical information system.

  8. Data Mining of Web-Based Documents on Social Networking Sites That Included Suicide-Related Words Among Korean Adolescents.

    Science.gov (United States)

    Song, Juyoung; Song, Tae Min; Seo, Dong-Chul; Jin, Jae Hyun

    2016-12-01

    To investigate online search activity of suicide-related words in South Korean adolescents through data mining of social media Web sites as the suicide rate in South Korea is one of the highest in the world. Out of more than 2.35 billion posts for 2 years from January 1, 2011 to December 31, 2012 on 163 social media Web sites in South Korea, 99,693 suicide-related documents were retrieved by Crawler and analyzed using text mining and opinion mining. These data were further combined with monthly employment rate, monthly rental prices index, monthly youth suicide rate, and monthly number of reported bully victims to fit multilevel models as well as structural equation models. The link from grade pressure to suicide risk showed the largest standardized path coefficient (beta = .357, p adolescents' suicide risk. Real-time suicide-related word search activity monitoring and response system needs to be developed. Copyright © 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  9. Active research fields in anesthesia: a document co-citation analysis of the anesthetic literature.

    Science.gov (United States)

    Jankovic, Milan P; Kaufmann, Mark; Kindler, Christoph H

    2008-05-01

    The expansion of science has resulted in an increased information flow and in an exponentially growing number of connections between knowledge in different research fields. In this study, we used methods of scientometric analysis to obtain a conceptual network that forms the structure of active scientific research fields in anesthesia. We extracted from the Web of Science (Institute for Scientific Information) all original articles (n = 3275) including their references (n = 79,972) that appeared in 2003 in all 23 journals listed in the Institute for Scientific Information Journal Citation Reports under the subject heading "Anesthesiology." After identification of highly cited references (> or = 5), pairs of co-cited references were created and grouped into uniformly structured clusters of documents using a single linkage and variable level clustering method. In addition, for each such cluster of documents, we identified corresponding front papers published in 2003, each of which co-cited at least two documents of the cluster core. Active anesthetic research fields were then named by examining the titles of the documents in both the established clusters and in their corresponding front papers. These research fields were sorted according to the proportion of recent documents in their cluster core (immediacy index) and were further analyzed. Forty-six current anesthetic research fields were identified. The research field named "ProSeal laryngeal mask airway" showed the highest immediacy index (100%) whereas the research fields "Experimental models of neuropathic pain" and "Volatile anesthetic-induced cardioprotection" exhibited the highest level of co-citation strength (level 9). The research field with the largest cluster core, containing 12 homogeneous papers, was "Postoperative nausea and vomiting." The journal Anesthesia & Analgesia published most front papers while Anesthesiology published most of the fundamental documents used as references in the front papers

  10. Promotion of physical activity in the European region: content analysis of 27 national policy documents

    DEFF Research Database (Denmark)

    Daugbjerg, Signe B; Kahlmeier, Sonja; Racioppi, Francesca

    2009-01-01

    search methods, 49 national policy documents on physical activity promotion were identified. An analysis grid covering key features was developed for the analysis of the 27 documents published in English. RESULTS: Analysis showed that many general recommendations for policy developments are being......BACKGROUND: Over the past years there has been increasing interest in physical activity promotion and the development of appropriate policy. So far, there has been no comprehensive overview of the activities taking place in Europe in this area of public health policy. METHODS: Using different...... followed, for example: general goals were formulated, an implementation plan was included, a timeframe and a responsible body for the implementation was often specified. However, limited evidence for intersectoral collaboration was found. Quantified goals for physical activity were the exception...

  11. 75 FR 24718 - Guidance for Industry on Documenting Statistical Analysis Programs and Data Files; Availability

    Science.gov (United States)

    2010-05-05

    ...] Guidance for Industry on Documenting Statistical Analysis Programs and Data Files; Availability AGENCY... documenting statistical analyses and data files submitted to the Center for Veterinary Medicine (CVM) for the... on Documenting Statistical Analysis Programs and Data Files; Availability'' giving interested persons...

  12. A Data Analysis of Naval Air Systems Command Funding Documents

    Science.gov (United States)

    2017-06-01

    value in excess of 146 billion dollars. NAVAIR uses the Navy Enterprise Resource Planning ( ERP ) system to process its financial transactions and...resource planning ( ERP ), Naval Air Systems Command (NAVAIR), purchase requests (PR), funding documents, Economy Act Order, intragovernmental transfers...Planning ( ERP ) system to process its financial transactions and, since its implementation, there has been an increase in the overall number of

  13. Combining Linguistic and Spatial Information for Document Analysis

    NARCIS (Netherlands)

    Aiello, Marco; Monz, Christof; Todoran, Leon

    2000-01-01

    We present a framework to analyze color documents of complex layout. In addition, no assumption is made on the layout. Our framework combines in a content-driven bottom-up approach two different sources of information: textual and spatial. To analyze the text, shallow natural language processing

  14. Two-dimensional analysis of motion artifacts, including flow effects

    International Nuclear Information System (INIS)

    Litt, A.M.; Brody, A.S.; Spangler, R.A.; Scott, P.D.

    1990-01-01

    The effects of motion on magnetic resonance images have been theoretically analyzed for the case of a point-like object in simple harmonic motion and for other one-dimensional trajectories. The authors of this paper extend this analysis to a generalized two-dimensional magnetization with an arbitrary motion trajectory. The authors provide specific solutions for the clinically relevant cases of the cross-sections of cylindrical objects in the body, such as the aorta, which has a roughly one-dimensional, simple harmonic motion during respiration. By extending the solution to include inhomogeneous magnetizations, the authors present a model which allows the effects of motion artifacts and flow artifacts to be analyzed simultaneously

  15. A Document-Driven Method for Certifying Scientific Computing Software for Use in Nuclear Safety Analysis

    Directory of Open Access Journals (Sweden)

    W. Spencer Smith

    2016-04-01

    Full Text Available This paper presents a documentation and development method to facilitate the certification of scientific computing software used in the safety analysis of nuclear facilities. To study the problems faced during quality assurance and certification activities, a case study was performed on legacy software used for thermal analysis of a fuelpin in a nuclear reactor. Although no errors were uncovered in the code, 27 issues of incompleteness and inconsistency were found with the documentation. This work proposes that software documentation follow a rational process, which includes a software requirements specification following a template that is reusable, maintainable, and understandable. To develop the design and implementation, this paper suggests literate programming as an alternative to traditional structured programming. Literate programming allows for documenting of numerical algorithms and code together in what is termed the literate programmer's manual. This manual is developed with explicit traceability to the software requirements specification. The traceability between the theory, numerical algorithms, and implementation facilitates achieving completeness and consistency, as well as simplifies the process of verification and the associated certification.

  16. A document-driven method for certifying scientific computing software for use in nuclear safety analysis

    International Nuclear Information System (INIS)

    Smith, W. Spencer; Koothoor, Mimitha

    2016-01-01

    This paper presents a documentation and development method to facilitate the certification of scientific computing software used in the safety analysis of nuclear facilities. To study the problems faced during quality assurance and certification activities, a case study was performed on legacy software used for thermal analysis of a fuel pin in a nuclear reactor. Although no errors were uncovered in the code, 27 issues of incompleteness and inconsistency were found with the documentation. This work proposes that software documentation follow a rational process, which includes a software requirements specification following a template that is reusable, maintainable, and understandable. To develop the design and implementation, this paper suggests literate programming as an alternative to traditional structured programming. Literate programming allows for documenting of numerical algorithms and code together in what is termed the literate programmer's manual. This manual is developed with explicit traceability to the software requirements specification. The traceability between the theory, numerical algorithms, and implementation facilitates achieving completeness and consistency, as well as simplifies the process of verification and the associated certification

  17. Ancient administrative handwritten documents: X-ray analysis and imaging

    Energy Technology Data Exchange (ETDEWEB)

    Albertin, F., E-mail: fauzia.albertin@epfl.ch [Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne (Switzerland); Astolfo, A. [Paul Scherrer Institut (PSI), Villigen (Switzerland); Stampanoni, M. [Paul Scherrer Institut (PSI), Villigen (Switzerland); ETHZ, Zürich (Switzerland); Peccenini, Eva [University of Ferrara (Italy); Technopole of Ferrara (Italy); Hwu, Y. [Academia Sinica, Taipei, Taiwan (China); Kaplan, F. [Ecole Polytechnique Fédérale de Lausanne (EPFL) (Switzerland); Margaritondo, G. [Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne (Switzerland)

    2015-01-30

    The heavy-element content of ink in ancient administrative documents makes it possible to detect the characters with different synchrotron imaging techniques, based on attenuation or refraction. This is the first step in the direction of non-interactive virtual X-ray reading. Handwritten characters in administrative antique documents from three centuries have been detected using different synchrotron X-ray imaging techniques. Heavy elements in ancient inks, present even for everyday administrative manuscripts as shown by X-ray fluorescence spectra, produce attenuation contrast. In most cases the image quality is good enough for tomography reconstruction in view of future applications to virtual page-by-page ‘reading’. When attenuation is too low, differential phase contrast imaging can reveal the characters from refractive index effects. The results are potentially important for new information harvesting strategies, for example from the huge Archivio di Stato collection, objective of the Venice Time Machine project.

  18. Promotion of physical activity in the European region: content analysis of 27 national policy documents

    DEFF Research Database (Denmark)

    Daugbjerg, Signe B; Kahlmeier, Sonja; Racioppi, Francesca

    2009-01-01

    search methods, 49 national policy documents on physical activity promotion were identified. An analysis grid covering key features was developed for the analysis of the 27 documents published in English. RESULTS: Analysis showed that many general recommendations for policy developments are being...... a noticeable development of national policy documents on physical activity promotion. Following principles for policy development more closely could increase the effectiveness of their preparation and implementation further....

  19. Global Nursing Issues and Development: Analysis of World Health Organization Documents.

    Science.gov (United States)

    Wong, Frances Kam Yuet; Liu, Huaping; Wang, Hui; Anderson, Debra; Seib, Charrlotte; Molasiotis, Alex

    2015-11-01

    To analyze World Health Organization (WHO) documents to identify global nursing issues and development. Qualitative content analysis. Documents published by the six WHO regions between 2007 and 2012 and with key words related to nurse/midwife or nursing/midwifery were included. Themes, categories, and subcategories were derived. The final coding reached 80% agreement among three independent coders, and the final coding for the discrepant coding was reached by consensus. Thirty-two documents from the regions of Europe (n = 19), the Americas (n = 6), the Western Pacific (n = 4), Africa (n = 1), the Eastern Mediterranean (n = 1), and Southeast Asia (n = 1) were examined. A total of 385 units of analysis dispersed in 31 subcategories under four themes were derived. The four themes derived (number of unit of analysis, %) were Management & Leadership (206, 53.5), Practice (75, 19.5), Education (70, 18.2), and Research (34, 8.8). The key nursing issues of concern at the global level are workforce, the impacts of nursing in health care, professional status, and education of nurses. International alliances can help advance nursing, but the visibility of nursing in the WHO needs to be strengthened. Organizational leadership is important in order to optimize the use of nursing competence in practice and inform policy makers regarding the value of nursing to promote people's health. © 2015 Sigma Theta Tau International.

  20. Energy analysis handbook. CAC document 214. [Combining process analysis with input-output analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bullard, C. W.; Penner, P. S.; Pilati, D. A.

    1976-10-01

    Methods are presented for calculating the energy required, directly and indirectly, to produce all types of goods and services. Procedures for combining process analysis with input-output analysis are described. This enables the analyst to focus data acquisition cost-effectively, and to achieve a specified degree of accuracy in the results. The report presents sample calculations and provides the tables and charts needed to perform most energy cost calculations, including the cost of systems for producing or conserving energy.

  1. Comparative Analysis of Document level Text Classification Algorithms using R

    Science.gov (United States)

    Syamala, Maganti; Nalini, N. J., Dr; Maguluri, Lakshamanaphaneendra; Ragupathy, R., Dr.

    2017-08-01

    From the past few decades there has been tremendous volumes of data available in Internet either in structured or unstructured form. Also, there is an exponential growth of information on Internet, so there is an emergent need of text classifiers. Text mining is an interdisciplinary field which draws attention on information retrieval, data mining, machine learning, statistics and computational linguistics. And to handle this situation, a wide range of supervised learning algorithms has been introduced. Among all these K-Nearest Neighbor(KNN) is efficient and simplest classifier in text classification family. But KNN suffers from imbalanced class distribution and noisy term features. So, to cope up with this challenge we use document based centroid dimensionality reduction(CentroidDR) using R Programming. By combining these two text classification techniques, KNN and Centroid classifiers, we propose a scalable and effective flat classifier, called MCenKNN which works well substantially better than CenKNN.

  2. K West integrated water treatment system subproject safety analysis document

    International Nuclear Information System (INIS)

    SEMMENS, L.S.

    1999-01-01

    This Accident Analysis evaluates unmitigated accident scenarios, and identifies Safety Significant and Safety Class structures, systems, and components for the K West Integrated Water Treatment System

  3. K West integrated water treatment system subproject safety analysis document

    Energy Technology Data Exchange (ETDEWEB)

    SEMMENS, L.S.

    1999-02-24

    This Accident Analysis evaluates unmitigated accident scenarios, and identifies Safety Significant and Safety Class structures, systems, and components for the K West Integrated Water Treatment System.

  4. ITER final design report, cost review and safety analysis (FDR) and relevant documents

    International Nuclear Information System (INIS)

    1999-01-01

    This volume contains the fourth major milestone report and documents associated with its acceptance, review and approval. This ITER Final Design Report, Cost Review and Safety Analysis was presented to the ITER Council at its 13th meeting in February 1998 and was approved at its extraordinary meeting on 25 June 1998. The contents include an outline of the ITER objectives, the ITER parameters and design overview as well as operating scenarios and plasma performance. Furthermore, design features, safety and environmental characteristics and schedule and cost estimates are given

  5. Attitude Determination Error Analysis System (ADEAS) mathematical specifications document

    Science.gov (United States)

    Nicholson, Mark; Markley, F.; Seidewitz, E.

    1988-01-01

    The mathematical specifications of Release 4.0 of the Attitude Determination Error Analysis System (ADEAS), which provides a general-purpose linear error analysis capability for various spacecraft attitude geometries and determination processes, are presented. The analytical basis of the system is presented. The analytical basis of the system is presented, and detailed equations are provided for both three-axis-stabilized and spin-stabilized attitude sensor models.

  6. Communications data delivery system analysis : public workshop read-ahead document.

    Science.gov (United States)

    2012-04-09

    This document presents an overview of work conducted to date around development and analysis of communications data delivery systems for : supporting transactions in the connected vehicle environment. It presents the results of technical analysis of ...

  7. Line outage contingency analysis including the system islanding ...

    African Journals Online (AJOL)

    The optimally ordered sparse [Bʹ], [Bʺ] matrices for the integrated system are used for load flow analysis to determine modified values of voltage phase angles [d] and bus voltages [V] to determine the over loading effect on the remaining lines due to outage of a selected line outage contingency. In case of over loading in ...

  8. Tools for voltage stability analysis, including a probabilistic approach

    Energy Technology Data Exchange (ETDEWEB)

    Vieira Filho, X.; Martins, N.; Bianco, A.; Pinto, H.J.C.P. [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil); Pereira, M.V.F. [Power System Research (PSR), Inc., Rio de Janeiro, RJ (Brazil); Gomes, P.; Santos, M.G. dos [ELETROBRAS, Rio de Janeiro, RJ (Brazil)

    1994-12-31

    This paper reviews some voltage stability analysis tools that are being used or envisioned for expansion and operational planning studies in the Brazilian system, as well as, their applications. The paper also shows that deterministic tools can be linked together in a probabilistic framework, so as to provide complementary help to the analyst in choosing the most adequate operation strategies, or the best planning solutions for a given system. (author) 43 refs., 8 figs., 8 tabs.

  9. New insights in forensic chemistry: NIR/Chemometrics analysis of toners for questioned documents examination.

    Science.gov (United States)

    Materazzi, Stefano; Risoluti, Roberta; Pinci, Sara; Saverio Romolo, Francesco

    2017-11-01

    Near-Infrared spectroscopy (NIRs) coupled to chemometrics was investigated for the first time as a new tool for the analysis of black toners to evaluate its application in forensic cases. Ten black toners from four manufacturers were included in this study and the acquired spectra were compared in order to differentiate toners. Multivariate statistical analysis based on Principal Component Analysis (PCA) was considered to develop a model of comparison of toners in questioned documents. Results demonstrated the capabilities of the approach NIR/Chemometrics to correctly identify toners when printed on different papers and to be not affected by the printing process. This study has shown that NIRs can be considered as a useful, fast, non-destructive tool providing the characterisation of toners in forensic caseworks. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Corpus analysis and automatic detection of emotion-including keywords

    Science.gov (United States)

    Yuan, Bo; He, Xiangqing; Liu, Ying

    2013-12-01

    Emotion words play a vital role in many sentiment analysis tasks. Previous research uses sentiment dictionary to detect the subjectivity or polarity of words. In this paper, we dive into Emotion-Inducing Keywords (EIK), which refers to the words in use that convey emotion. We first analyze an emotion corpus to explore the pragmatic aspects of EIK. Then we design an effective framework for automatically detecting EIK in sentences by utilizing linguistic features and context information. Our system outperforms traditional dictionary-based methods dramatically in increasing Precision, Recall and F1-score.

  11. A Similarity-Based Approach for Audiovisual Document Classification Using Temporal Relation Analysis

    Directory of Open Access Journals (Sweden)

    Ferrane Isabelle

    2011-01-01

    Full Text Available Abstract We propose a novel approach for video classification that bases on the analysis of the temporal relationships between the basic events in audiovisual documents. Starting from basic segmentation results, we define a new representation method that is called Temporal Relation Matrix (TRM. Each document is then described by a set of TRMs, the analysis of which makes events of a higher level stand out. This representation has been first designed to analyze any audiovisual document in order to find events that may well characterize its content and its structure. The aim of this work is to use this representation to compute a similarity measure between two documents. Approaches for audiovisual documents classification are presented and discussed. Experimentations are done on a set of 242 video documents and the results show the efficiency of our proposals.

  12. Line outage contingency analysis including the system islanding scenario

    Energy Technology Data Exchange (ETDEWEB)

    Hazarika, D.; Bhuyan, S. [Assam Engineering College, Jalukbari, Guwahati 781013 (India); Chowdhury, S.P. [Jadavpur University, Jadavpur, Kolkata 700 032 (India)

    2006-05-15

    The paper describes an algorithm for determining the line outage contingency of a line taking into account of line over load effect in remaining lines and subsequent tripping of over loaded line(s) leading to possible system split or islanding of a power system. The optimally ordered sparse [B'], [B'] matrices for the integrated system are used for load flow analysis to determine modified values of voltage phase angles [{delta}] and bus voltages [V] to determine the over loading effect on the remaining lines due to outage of a selected line outage contingency. In case of over loading in remaining line(s), the over loaded lines are removed from the system and a topology processor is used to find the islands. A fast decoupled load flow (FDLF) analysis is carried out for finding out the system variables for the islanded (or single island) system by incorporating appropriate modification in the [B'] and [B'] matrices of the integrated system. Line outage indices based on line overload, loss of load, loss of generation and static voltage stability are computed to indicate severity of a line outage of a selected line. (author)

  13. Obtaining informed consent for genomics research in Africa: analysis of H3Africa consent documents.

    Science.gov (United States)

    Munung, Nchangwi Syntia; Marshall, Patricia; Campbell, Megan; Littler, Katherine; Masiye, Francis; Ouwe-Missi-Oukem-Boyer, Odile; Seeley, Janet; Stein, D J; Tindana, Paulina; de Vries, Jantina

    2016-02-01

    The rise in genomic and biobanking research worldwide has led to the development of different informed consent models for use in such research. This study analyses consent documents used by investigators in the H3Africa (Human Heredity and Health in Africa) Consortium. A qualitative method for text analysis was used to analyse consent documents used in the collection of samples and data in H3Africa projects. Thematic domains included type of consent model, explanations of genetics/genomics, data sharing and feedback of test results. Informed consent documents for 13 of the 19 H3Africa projects were analysed. Seven projects used broad consent, five projects used tiered consent and one used specific consent. Genetics was mostly explained in terms of inherited characteristics, heredity and health, genes and disease causation, or disease susceptibility. Only one project made provisions for the feedback of individual genetic results. H3Africa research makes use of three consent models-specific, tiered and broad consent. We outlined different strategies used by H3Africa investigators to explain concepts in genomics to potential research participants. To further ensure that the decision to participate in genomic research is informed and meaningful, we recommend that innovative approaches to the informed consent process be developed, preferably in consultation with research participants, research ethics committees and researchers in Africa. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  14. Dynamic Analysis of Wind Turbines Including Soil-Structure Interaction

    DEFF Research Database (Denmark)

    Harte, M.; Basu, B.; Nielsen, Søren R.K.

    2012-01-01

    blades and includes the effect of centrifugal stiffening due to rotation. The foundation of the structure is modeled as a rigid gravity based foundation with two DOF whose movement is related to the surrounding soil by means of complex impedance functions generated using cone model. Transfer functions...... for displacement of the turbine system are obtained and the modal frequencies of the combined turbine-foundation system are estimated. Simulations are presented for the MDOF turbine structure subjected to wind loading for different soil stiffness conditions. Steady state and turbulent wind loading, developed using...... blade element momentum theory and the Kaimal spectrum, have been considered. Soil stiffness and damping properties acquired from DNV/Risø standards are used as a comparison. The soil-structure interaction is shown to affect the response of the wind turbine. This is examined in terms of the turbine...

  15. IGSA: Individual Gene Sets Analysis, including Enrichment and Clustering.

    Science.gov (United States)

    Wu, Lingxiang; Chen, Xiujie; Zhang, Denan; Zhang, Wubing; Liu, Lei; Ma, Hongzhe; Yang, Jingbo; Xie, Hongbo; Liu, Bo; Jin, Qing

    2016-01-01

    Analysis of gene sets has been widely applied in various high-throughput biological studies. One weakness in the traditional methods is that they neglect the heterogeneity of genes expressions in samples which may lead to the omission of some specific and important gene sets. It is also difficult for them to reflect the severities of disease and provide expression profiles of gene sets for individuals. We developed an application software called IGSA that leverages a powerful analytical capacity in gene sets enrichment and samples clustering. IGSA calculates gene sets expression scores for each sample and takes an accumulating clustering strategy to let the samples gather into the set according to the progress of disease from mild to severe. We focus on gastric, pancreatic and ovarian cancer data sets for the performance of IGSA. We also compared the results of IGSA in KEGG pathways enrichment with David, GSEA, SPIA, ssGSEA and analyzed the results of IGSA clustering and different similarity measurement methods. Notably, IGSA is proved to be more sensitive and specific in finding significant pathways, and can indicate related changes in pathways with the severity of disease. In addition, IGSA provides with significant gene sets profile for each sample.

  16. Shunted Piezoelectric Vibration Damping Analysis Including Centrifugal Loading Effects

    Science.gov (United States)

    Min, James B.; Duffy, Kirsten P.; Provenza, Andrew J.

    2011-01-01

    Excessive vibration of turbomachinery blades causes high cycle fatigue problems which require damping treatments to mitigate vibration levels. One method is the use of piezoelectric materials as passive or active dampers. Based on the technical challenges and requirements learned from previous turbomachinery rotor blades research, an effort has been made to investigate the effectiveness of a shunted piezoelectric for the turbomachinery rotor blades vibration control, specifically for a condition with centrifugal rotation. While ample research has been performed on the use of a piezoelectric material with electric circuits to attempt to control the structural vibration damping, very little study has been done regarding rotational effects. The present study attempts to fill this void. Specifically, the objectives of this study are: (a) to create and analyze finite element models for harmonic forced response vibration analysis coupled with shunted piezoelectric circuits for engine blade operational conditions, (b) to validate the experimental test approaches with numerical results and vice versa, and (c) to establish a numerical modeling capability for vibration control using shunted piezoelectric circuits under rotation. Study has focused on a resonant damping control using shunted piezoelectric patches on plate specimens. Tests and analyses were performed for both non-spinning and spinning conditions. The finite element (FE) shunted piezoelectric circuit damping simulations were performed using the ANSYS Multiphysics code for the resistive and inductive circuit piezoelectric simulations of both conditions. The FE results showed a good correlation with experimental test results. Tests and analyses of shunted piezoelectric damping control, demonstrating with plate specimens, show a great potential to reduce blade vibrations under centrifugal loading.

  17. Underground Test Area Subproject Phase I Data Analysis Task. Volume VIII - Risk Assessment Documentation Package

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-12-01

    Volume VIII of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the risk assessment documentation. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  18. Underground Test Area Subproject Phase I Data Analysis Task. Volume VII - Tritium Transport Model Documentation Package

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-12-01

    Volume VII of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the tritium transport model documentation. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  19. A Document Analysis of Teacher Evaluation Systems Specific to Physical Education

    Science.gov (United States)

    Norris, Jason M.; van der Mars, Hans; Kulinna, Pamela; Kwon, Jayoun; Amrein-Beardsley, Audrey

    2017-01-01

    Purpose: The purpose of this document analysis study was to examine current teacher evaluation systems, understand current practices, and determine whether the instrumentation is a valid measure of teaching quality as reflected in teacher behavior and effectiveness specific to physical education (PE). Method: An interpretive document analysis…

  20. A FRAMEWORK FOR DOCUMENT PRE-PROCESSING IN FORENSIC HANDWRITING ANALYSIS

    NARCIS (Netherlands)

    Franke, K.; Köppen, M.

    2004-01-01

    We propose an open layered framework, which might be adapted to fulfill sophisticated demands in forensic handwriting analysis. Due to the contradicting requirements of processing a huge amount of different document types as well as providing high quality processed images of singular document

  1. CoIN: a network analysis for document triage.

    Science.gov (United States)

    Hsu, Yi-Yu; Kao, Hung-Yu

    2013-01-01

    In recent years, there was a rapid increase in the number of medical articles. The number of articles in PubMed has increased exponentially. Thus, the workload for biocurators has also increased exponentially. Under these circumstances, a system that can automatically determine in advance which article has a higher priority for curation can effectively reduce the workload of biocurators. Determining how to effectively find the articles required by biocurators has become an important task. In the triage task of BioCreative 2012, we proposed the Co-occurrence Interaction Nexus (CoIN) for learning and exploring relations in articles. We constructed a co-occurrence analysis system, which is applicable to PubMed articles and suitable for gene, chemical and disease queries. CoIN uses co-occurrence features and their network centralities to assess the influence of curatable articles from the Comparative Toxicogenomics Database. The experimental results show that our network-based approach combined with co-occurrence features can effectively classify curatable and non-curatable articles. CoIN also allows biocurators to survey the ranking lists for specific queries without reviewing meaningless information. At BioCreative 2012, CoIN achieved a 0.778 mean average precision in the triage task, thus finishing in second place out of all participants. Database URL: http://ikmbio.csie.ncku.edu.tw/coin/home.php.

  2. Model-based document categorization employing semantic pattern analysis and local structure clustering

    Science.gov (United States)

    Fume, Kosei; Ishitani, Yasuto

    2008-01-01

    We propose a document categorization method based on a document model that can be defined externally for each task and that categorizes Web content or business documents into a target category in accordance with the similarity of the model. The main feature of the proposed method consists of two aspects of semantics extraction from an input document. The semantics of terms are extracted by the semantic pattern analysis and implicit meanings of document substructure are specified by a bottom-up text clustering technique focusing on the similarity of text line attributes. We have constructed a system based on the proposed method for trial purposes. The experimental results show that the system achieves more than 80% classification accuracy in categorizing Web content and business documents into 15 or 70 categories.

  3. Final safety analysis report for the Galileo Mission: Volume 2, Book 2: Accident model document: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    1988-12-15

    This section of the Accident Model Document (AMD) presents the appendices which describe the various analyses that have been conducted for use in the Galileo Final Safety Analysis Report II, Volume II. Included in these appendices are the approaches, techniques, conditions and assumptions used in the development of the analytical models plus the detailed results of the analyses. Also included in these appendices are summaries of the accidents and their associated probabilities and environment models taken from the Shuttle Data Book (NSTS-08116), plus summaries of the several segments of the recent GPHS safety test program. The information presented in these appendices is used in Section 3.0 of the AMD to develop the Failure/Abort Sequence Trees (FASTs) and to determine the fuel releases (source terms) resulting from the potential Space Shuttle/IUS accidents throughout the missions.

  4. Final safety analysis report for the Galileo Mission: Volume 1, Reference design document

    Energy Technology Data Exchange (ETDEWEB)

    1988-05-01

    The Galileo mission uses nuclear power sources called Radioisotope Thermoelectric Generators (RTGs) to provide the spacecraft's primary electrical power. Because these generators contain nuclear material, a Safety Analysis Report (SAR) is required. A preliminary SAR and an updated SAR were previously issued that provided an evolving status report on the safety analysis. As a result of the Challenger accident, the launch dates for both Galileo and Ulysses missions were later rescheduled for November 1989 and October 1990, respectively. The decision was made by agreement between the DOE and the NASA to have a revised safety evaluation and report (FSAR) prepared on the basis of these revised vehicle accidents and environments. The results of this latest revised safety evaluation are presented in this document (Galileo FSAR). Volume I, this document, provides the background design information required to understand the analyses presented in Volumes II and III. It contains descriptions of the RTGs, the Galileo spacecraft, the Space Shuttle, the Inertial Upper Stage (IUS), the trajectory and flight characteristics including flight contingency modes, and the launch site. There are two appendices in Volume I which provide detailed material properties for the RTG.

  5. Language Ideology or Language Practice? An Analysis of Language Policy Documents at Swedish Universities

    Science.gov (United States)

    Björkman, Beyza

    2014-01-01

    This article presents an analysis and interpretation of language policy documents from eight Swedish universities with regard to intertextuality, authorship and content analysis of the notions of language practices and English as a lingua franca (ELF). The analysis is then linked to Spolsky's framework of language policy, namely language…

  6. Public health human resources: a comparative analysis of policy documents in two Canadian provinces

    Science.gov (United States)

    2014-01-01

    Background Amidst concerns regarding the capacity of the public health system to respond rapidly and appropriately to threats such as pandemics and terrorism, along with changing population health needs, governments have focused on strengthening public health systems. A key factor in a robust public health system is its workforce. As part of a nationally funded study of public health renewal in Canada, a policy analysis was conducted to compare public health human resources-relevant documents in two Canadian provinces, British Columbia (BC) and Ontario (ON), as they each implement public health renewal activities. Methods A content analysis of policy and planning documents from government and public health-related organizations was conducted by a research team comprised of academics and government decision-makers. Documents published between 2003 and 2011 were accessed (BC = 27; ON = 20); documents were either publicly available or internal to government and excerpted with permission. Documentary texts were deductively coded using a coding template developed by the researchers based on key health human resources concepts derived from two national policy documents. Results Documents in both provinces highlighted the importance of public health human resources planning and policies; this was particularly evident in early post-SARS documents. Key thematic areas of public health human resources identified were: education, training, and competencies; capacity; supply; intersectoral collaboration; leadership; public health planning context; and priority populations. Policy documents in both provinces discussed the importance of an educated, competent public health workforce with the appropriate skills and competencies for the effective and efficient delivery of public health services. Conclusion This policy analysis identified progressive work on public health human resources policy and planning with early documents providing an inventory of issues to be

  7. Integrated computer-aided forensic case analysis, presentation, and documentation based on multimodal 3D data.

    Science.gov (United States)

    Bornik, Alexander; Urschler, Martin; Schmalstieg, Dieter; Bischof, Horst; Krauskopf, Astrid; Schwark, Thorsten; Scheurer, Eva; Yen, Kathrin

    2018-03-23

    Three-dimensional (3D) crime scene documentation using 3D scanners and medical imaging modalities like computed tomography (CT) and magnetic resonance imaging (MRI) are increasingly applied in forensic casework. Together with digital photography, these modalities enable comprehensive and non-invasive recording of forensically relevant information regarding injuries/pathologies inside the body and on its surface. Furthermore, it is possible to capture traces and items at crime scenes. Such digitally secured evidence has the potential to similarly increase case understanding by forensic experts and non-experts in court. Unlike photographs and 3D surface models, images from CT and MRI are not self-explanatory. Their interpretation and understanding requires radiological knowledge. Findings in tomography data must not only be revealed, but should also be jointly studied with all the 2D and 3D data available in order to clarify spatial interrelations and to optimally exploit the data at hand. This is technically challenging due to the heterogeneous data representations including volumetric data, polygonal 3D models, and images. This paper presents a novel computer-aided forensic toolbox providing tools to support the analysis, documentation, annotation, and illustration of forensic cases using heterogeneous digital data. Conjoint visualization of data from different modalities in their native form and efficient tools to visually extract and emphasize findings help experts to reveal unrecognized correlations and thereby enhance their case understanding. Moreover, the 3D case illustrations created for case analysis represent an efficient means to convey the insights gained from case analysis to forensic non-experts involved in court proceedings like jurists and laymen. The capability of the presented approach in the context of case analysis, its potential to speed up legal procedures and to ultimately enhance legal certainty is demonstrated by introducing a number of

  8. Analysis of a risk prevention document using dependability techniques: a first step towards an effectiveness model

    Science.gov (United States)

    Ferrer, Laetitia; Curt, Corinne; Tacnet, Jean-Marc

    2018-04-01

    Major hazard prevention is a main challenge given that it is specifically based on information communicated to the public. In France, preventive information is notably provided by way of local regulatory documents. Unfortunately, the law requires only few specifications concerning their content; therefore one can question the impact on the general population relative to the way the document is concretely created. Ergo, the purpose of our work is to propose an analytical methodology to evaluate preventive risk communication document effectiveness. The methodology is based on dependability approaches and is applied in this paper to the Document d'Information Communal sur les Risques Majeurs (DICRIM; in English, Municipal Information Document on Major Risks). DICRIM has to be made by mayors and addressed to the public to provide information on major hazards affecting their municipalities. An analysis of law compliance of the document is carried out thanks to the identification of regulatory detection elements. These are applied to a database of 30 DICRIMs. This analysis leads to a discussion on points such as usefulness of the missing elements. External and internal function analysis permits the identification of the form and content requirements and service and technical functions of the document and its components (here its sections). Their results are used to carry out an FMEA (failure modes and effects analysis), which allows us to define the failure and to identify detection elements. This permits the evaluation of the effectiveness of form and content of each components of the document. The outputs are validated by experts from the different fields investigated. Those results are obtained to build, in future works, a decision support model for the municipality (or specialised consulting firms) in charge of drawing up documents.

  9. Analysis and evaluation of magnetism of black toners on documents printed by electrophotographic systems.

    Science.gov (United States)

    Biedermann, A; Bozza, S; Taroni, F; Fürbach, M; Li, B; Mazzella, W D

    2016-10-01

    This paper reports on a study to assess the potential of measurements of magnetism, using a proprietary magnetic analysis system, for the routine analysis of toners on documents printed by black and white electrophotographic systems. Magnetic properties of black toners on documents printed by a number of different devices were measured and compared. Our results indicate that the analysis of magnetism is complementary to traditional methods for analysing black toners, such as FTIR. Further, we find that the analysis of magnetism is realistically applicable in closed set cases, that is when the number of potential printing devices can be clearly defined. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  10. A document analysis of drowning prevention education resources in the United States.

    Science.gov (United States)

    Katchmarchi, Adam Bradley; Taliaferro, Andrea R; Kipfer, Hannah Joy

    2018-03-01

    There have been long-standing calls to better educate the public at large on risks of drowning; yet limited evaluation has taken place on current resources in circulation. The purpose of this qualitative research is to develop an understanding of the content in currently circulated drowning prevention resources in the United States. Data points (n = 451) consisting of specific content within 25 different drowning prevention educational resources were analyzed using document analysis methods; a grounded theory approach was employed to allow for categorical development and indexing of the data. Results revealed six emerging categories, including safety precautions (n = 152), supervision (n = 109), preventing access (n = 57), safety equipment (n = 46), emergency procedures (n = 46), and aquatic education (n = 41). Results provide an initial insight into the composition of drowning prevention resources in the United States and provide a foundation for future research.

  11. How do hospitals deal with euthanasia requests in Flanders (Belgium)? A content analysis of policy documents.

    Science.gov (United States)

    Lemiengre, Joke; Dierckx de Casterlé, Bernadette; Denier, Yvonne; Schotsmans, Paul; Gastmans, Chris

    2008-05-01

    To describe the form and content of ethics policies on euthanasia in Flemish hospitals and the possible influence of religious affiliation on policy content. Content analysis of policy documents. Forty-two documents were analyzed. All policies contained procedures; 57% included the position paper on which the hospital's stance on euthanasia was based. All policies described their hospital's stance on euthanasia in competent terminally ill patients (n=42); 10 and 4 policies, respectively, did not describe their stance in incompetent terminally and non-terminally ill patients. Catholic hospitals restrictively applied the euthanasia law with palliative procedures and interdisciplinary deliberations. The policies described several phases of the euthanasia care process--confrontation with euthanasia request (93%), decision-making process (95%), care process in cases of no-euthanasia decision (38%), preparation and performance of euthanasia (79%), and aftercare (81%)--as well as involvement of caregivers, patients, and relatives; ethical issues; support for caregivers; reporting; and practical examples of professional attitudes and communication skills. Euthanasia policies go beyond summarizing the euthanasia law by addressing the importance of the euthanasia care process, in which palliative care and interdisciplinary cooperation are important factors. Euthanasia policies provide tangible guidance for physicians and nurses on handling euthanasia requests.

  12. DOE Integrated Safeguards and Security (DISS) historical document archival and retrieval analysis, requirements and recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Guyer, H.B.; McChesney, C.A.

    1994-10-07

    The overall primary Objective of HDAR is to create a repository of historical personnel security documents and provide the functionality needed for archival and retrieval use by other software modules and application users of the DISS/ET system. The software product to be produced from this specification is the Historical Document Archival and Retrieval Subsystem The product will provide the functionality to capture, retrieve and manage documents currently contained in the personnel security folders in DOE Operations Offices vaults at various locations across the United States. The long-term plan for DISS/ET includes the requirement to allow for capture and storage of arbitrary, currently undefined, clearance-related documents that fall outside the scope of the ``cradle-to-grave`` electronic processing provided by DISS/ET. However, this requirement is not within the scope of the requirements specified in this document.

  13. Adapting Spectral Co-clustering to Documents and Terms Using Latent Semantic Analysis

    Science.gov (United States)

    Park, Laurence A. F.; Leckie, Christopher A.; Ramamohanarao, Kotagiri; Bezdek, James C.

    Spectral co-clustering is a generic method of computing co-clusters of relational data, such as sets of documents and their terms. Latent semantic analysis is a method of document and term smoothing that can assist in the information retrieval process. In this article we examine the process behind spectral clustering for documents and terms, and compare it to Latent Semantic Analysis. We show that both spectral co-clustering and LSA follow the same process, using different normalisation schemes and metrics. By combining the properties of the two co-clustering methods, we obtain an improved co-clustering method for document-term relational data that provides an increase in the cluster quality of 33.0%.

  14. The practical implementation of integrated safety management for nuclear safety analysis and fire hazards analysis documentation

    International Nuclear Information System (INIS)

    COLLOPY, M.T.

    1999-01-01

    the integrated safety management system approach for having a uniform and consistent process: a method has been suggested by the U S . Department of Energy at Richland and the Project Hanford Procedures when fire hazard analyses and safety analyses are required. This process provides for a common basis approach in the development of the fire hazard analysis and the safety analysis. This process permits the preparers of both documents to jointly participate in the development of the hazard analysis process. This paper presents this method to implement the integrated safety management approach in the development of the fire hazard analysis and safety analysis that provides consistency of assumptions. consequences, design considerations, and other controls necessarily to protect workers, the public. and the environment

  15. 'Including health in systems responsible for urban planning': a realist policy analysis research programme.

    Science.gov (United States)

    Harris, Patrick; Friel, Sharon; Wilson, Andrew

    2015-07-23

    Realist methods are increasingly being used to investigate complex public health problems. Despite the extensive evidence base clarifying the built environment as a determinant of health, there is limited knowledge about how and why land-use planning systems take on health concerns. Further, the body of research related to the wider determinants of health suffers from not using political science knowledge to understand how to influence health policy development and systems. This 4-year funded programme of research investigates how the land-use planning system in New South Wales, Australia, incorporates health and health equity at multiple levels. The programme uses multiple qualitative methods to develop up to 15 case studies of different activities of the New South Wales land-use planning system. Comparison cases from other jurisdictions will be included where possible and useful. Data collection includes publicly available documentation and purposively sampled stakeholder interviews and focus groups of up to 100 participants across the cases. The units of analysis in each case are institutional structures (rules and mandates constraining and enabling actors), actors (the stakeholders, organisations and networks involved, including health-focused agencies), and ideas (policy content, information, and framing). Data analysis will focus on and develop propositions concerning the mechanisms and conditions within and across each case leading to inclusion or non-inclusion of health. Data will be refined using additional political science and sociological theory. Qualitative comparative analysis will compare cases to develop policy-relevant propositions about the necessary and sufficient conditions needed to include health issues. Ethics has been approved by Sydney University Human Research Ethics Committee (2014/802 and 2015/178). Given the nature of this research we will incorporate stakeholders, often as collaborators, throughout. We outline our research translation

  16. In-air PIXE set-up for automatic analysis of historical document inks

    Science.gov (United States)

    Budnar, Miloš; Simčič, Jure; Rupnik, Zdravko; Uršič, Mitja; Pelicon, Primož; Kolar, Jana; Strlič, Matija

    2004-06-01

    The iron gall inks were one of the writing materials mostly applied in historical documents of the western civilization. Due to the ink corrosive character, the documents are faced with a danger of being seriously, and in some cases also irreversibly changed. The elemental composition of the inks is an important information for taking the adequate conservation action [Project InkCor, http://www.infosrvr.nuk.uni-lj.si/jana/Inkcor/index.htm, and references within]. Here, the in-air PIXE analysis offers an indispensable tool due to its sensitivity and almost non-destructive character. An experimental approach developed for precise and automatic analysis of documents at Jožef Stefan Institute Tandetron accelerator is presented. The selected documents were mounted, one at the time, on the positioning board and the chosen ink spots on the sample were irradiated by 1.7 MeV protons. The data acquisition on the selected ink spots is done automatically throughout the measuring pattern determined prior to the measurement. The chemical elements identified in the documents ranged from Si to Pb, and between them the significant iron gall ink components like Fe, S, K, Cu, Zn, Co, Mn, Ni were deduced with precision of ±10%. The measurements were done non-destructively and no visible damage was observed on the irradiated documents.

  17. Local development strategies for inner areas in Italy. A comparative analysis based on plan documents

    Directory of Open Access Journals (Sweden)

    Gabriella Punziano

    2016-12-01

    Full Text Available Within the huge literature on local development policies produced across different disciplines, comparatively little attention has been paid to an important element as relevant as economic, financial and social capital: the cognitive element, needed in strategic thinking and complexity management, the “collective brain” guiding the decision-making process. In this paper, we investigate what we consider a direct “proxy” for this variable, which is supposed to incorporate that “usable knowledge” assisting those making policy choices: language. Language shapes the way problems are conceived, fixes priorities and delimits the range of strategic options. More specifically, our research question inquires which contextual factors are at stake in local development strategy design. The case studies were chosen among the pilot areas included in the Italian “National Strategy for Inner Areas”. Through a multidimensional content analysis of the plan documents available online, we explored the ways in which development strategies are locally interpreted. The techniques we used allowed us to make a comparative analysis, testing three effects that could have influenced local policy design: a geographical effect, a concept/policy transfer effect, and a framing effect. Broader, interesting reflections were drawn from research findings on the local embedded ability to designing consistent and effective development strategies.

  18. Violência contra os idosos: análise documental Violencia contra los ancianos: análisis documental Violence against the aged: documental analysis

    Directory of Open Access Journals (Sweden)

    Jacy Aurélia Vieira de Souza

    2007-06-01

    Full Text Available O objetivo do estudo foi analisar os dados de violência e maus-tratos contra os idosos por meio de documentos oficiais, em Fortaleza-CE. Estudo retrospectivo, documental realizada em uma instituição de referência do Ceará, oficializada em denúncias de violência contra idosos. A coleta de dados ocorreu no primeiro semestre de 2005. Dos 424 documentos analisados, 284(67% identificou-se como abandono dos idosos. Quanto ao agressor, 207(49% era filho da vítima. Dentre os casos de violências, 161 (38% foi negligência, seguido por apropriação indébita de aposentadoria, 114 (27%; agressão verbal, 79(19% e física 68(16%. Tais eventos foram registrados por meio de denúncias, principalmente, ao serviço Alô-Idoso, 306(77%. Pôde-se verificar a importância de serviços voltados para essa questão, porém torna-se fundamental que políticas públicas enfoquem o papel social do idoso e privilegiem o cuidado e a proteção dessa parcela populacional em suas famílias e instituições.Lo estudio tuvo como objetivo analizar los datos sobre violencia contra los ancianos en la contexto familiar. Se realizó un estudio documental retrospectivo en una institución de referencia de Ceará, con oficialización en reclamaciones de violencia contra los ancianos. Se coletaron los datos en enero a julio de 2005. Se compilaron 424 datos. Se constató que 284 (67%, caso de violencia ocurrieron a los ancianos de sexo femenino. Con relación a los agresores, 207 (49%, eran hijos de las víctimas. Entre los tipos de violencia, 161(38% son negligencia, 114 (27%, la apropiación indebida de lo jubilación; la agresión verbal, 79 (19%, y la agresión físico, 68 (16%. Se ha podido identificar la importancia de servicio a cerca de la cuestión, no obstante, se resulta fundamental que políticas públicas de ese porcentaje de la población proyecten la función social del anciano, a sí convalorar el cuidado y la protección de ese porcentaje poblacional en sus

  19. Analysis of Nature of Science Included in Recent Popular Writing Using Text Mining Techniques

    Science.gov (United States)

    Jiang, Feng; McComas, William F.

    2014-09-01

    This study examined the inclusion of nature of science (NOS) in popular science writing to determine whether it could serve supplementary resource for teaching NOS and to evaluate the accuracy of text mining and classification as a viable research tool in science education research. Four groups of documents published from 2001 to 2010 were analyzed: Scientific American, Discover magazine, winners of the Royal Society Winton Prize for Science Books, and books from NSTA's list of Outstanding Science Trade Books. Computer analysis categorized passages in the selected documents based on their inclusions of NOS. Human analysis assessed the frequency, context, coverage, and accuracy of the inclusions of NOS within computer identified NOS passages. NOS was rarely addressed in selected document sets but somewhat more frequently addressed in the letters section of the two magazines. This result suggests that readers seem interested in the discussion of NOS-related themes. In the popular science books analyzed, NOS presentations were found more likely to be aggregated in the beginning and the end of the book, rather than scattered throughout. The most commonly addressed NOS elements in the analyzed documents are science and society and empiricism in science. Only one inaccurate presentation of NOS were identified in all analyzed documents. The text mining technique demonstrated exciting performance, which invites more applications of the technique to analyze other aspects of science textbooks, popular science writing, or other materials involved in science teaching and learning.

  20. Documentation and Analysis of Children's Experience: An Ongoing Collegial Activity for Early Childhood Professionals

    Science.gov (United States)

    Picchio, Mariacristina; Giovannini, Donatella; Mayer, Susanna; Musatti, Tullia

    2012-01-01

    Systematic documentation and analysis of educational practice can be a powerful tool for continuous support to the professionalism of early childhood education practitioners. This paper discusses data from a three-year action-research initiative carried out by a research agency in collaboration with a network of Italian municipal "nido"…

  1. Spent nuclear fuel project - criteria document spent nuclear fuel final safety analysis report

    International Nuclear Information System (INIS)

    MORGAN, R.G.

    1999-01-01

    The criteria document provides the criteria and planning guidance for developing the Spent Nuclear Fuel (SNF) Final Safety Analysis Report (FSAR). This FSAR will support the US Department of Energy, Richland Operations Office decision to authorize the procurement, installation, installation acceptance testing, startup, and operation of the SNF Project facilities (K Basins, Cold Vacuum Drying Facility, and Canister Storage Building)

  2. The Role of Business Agreements in Defining Textbook Affordability and Digital Materials: A Document Analysis

    Science.gov (United States)

    Raible, John; deNoyelles, Aimee

    2015-01-01

    Adopting digital materials such as eTextbooks and e-coursepacks is a potential strategy to address textbook affordability in the United States. However, university business relationships with bookstore vendors implicitly structure which instructional resources are available and in what manner. In this study, a document analysis was conducted on…

  3. Requirement analysis for citizen observatories (including stakeholder sensor adoption and usage). D6.21

    OpenAIRE

    McCarthy, Simon; Tapsell, Sue M.; McDonagh, Rosalind; Vita, Lanfranchi; Kim, Anema; Uta, Wehn de Montalvo

    2014-01-01

    This document presents the report on the initial requirements analysis for citizen observatories of water that are designed, developed and implemented during the WeSenseIt project. The observatories will be tested in three distinct case study locations: Doncaster (UK), Delfland (NL) and Alto Adriatico (Italy). The report focuses on the initial requirements analysis of stakeholders in terms of their preferences for the technological components of the citizen observatory for the design and use ...

  4. Content analysis to detect high stress in oral interviews and text documents

    Science.gov (United States)

    Thirumalainambi, Rajkumar (Inventor); Jorgensen, Charles C. (Inventor)

    2012-01-01

    A system of interrogation to estimate whether a subject of interrogation is likely experiencing high stress, emotional volatility and/or internal conflict in the subject's responses to an interviewer's questions. The system applies one or more of four procedures, a first statistical analysis, a second statistical analysis, a third analysis and a heat map analysis, to identify one or more documents containing the subject's responses for which further examination is recommended. Words in the documents are characterized in terms of dimensions representing different classes of emotions and states of mind, in which the subject's responses that manifest high stress, emotional volatility and/or internal conflict are identified. A heat map visually displays the dimensions manifested by the subject's responses in different colors, textures, geometric shapes or other visually distinguishable indicia.

  5. Analysis of laser and inkjet prints using spectroscopic methods for forensic identification of questioned documents

    OpenAIRE

    Gál, Lukáš; Belovičová, Michaela; Oravec, Michal; Palková, Miroslava; Čeppan, Michal

    2013-01-01

    The spectral properties in UV-VIS-NIR and IR regions of laser and inkjet prints were studied for the purposes of forensic analysis of documents. The procedures of measurements and processing of spectra of printed documents using fibre optics reflectance spectroscopy in UV-VIS and NIR region, FTIR-ATR with diamond/ZnSe and germanium crystals were optimized. It was found that the shapes of spectra of various black laser jet prints and inkjet prints generally differ in the spectral regions...

  6. Application of multi-resolution 3D techniques in crime scene documentation with bloodstain pattern analysis.

    Science.gov (United States)

    Hołowko, Elwira; Januszkiewicz, Kamil; Bolewicki, Paweł; Sitnik, Robert; Michoński, Jakub

    2016-10-01

    In forensic documentation with bloodstain pattern analysis (BPA) it is highly desirable to obtain non-invasively overall documentation of a crime scene, but also register in high resolution single evidence objects, like bloodstains. In this study, we propose a hierarchical 3D scanning platform designed according to the top-down approach known from the traditional forensic photography. The overall 3D model of a scene is obtained via integration of laser scans registered from different positions. Some parts of a scene being particularly interesting are documented using midrange scanner, and the smallest details are added in the highest resolution as close-up scans. The scanning devices are controlled using developed software equipped with advanced algorithms for point cloud processing. To verify the feasibility and effectiveness of multi-resolution 3D scanning in crime scene documentation, our platform was applied to document a murder scene simulated by the BPA experts from the Central Forensic Laboratory of the Police R&D, Warsaw, Poland. Applying the 3D scanning platform proved beneficial in the documentation of a crime scene combined with BPA. The multi-resolution 3D model enables virtual exploration of a scene in a three-dimensional environment, distance measurement, and gives a more realistic preservation of the evidences together with their surroundings. Moreover, high-resolution close-up scans aligned in a 3D model can be used to analyze bloodstains revealed at the crime scene. The result of BPA such as trajectories, and the area of origin are visualized and analyzed in an accurate model of a scene. At this stage, a simplified approach considering the trajectory of blood drop as a straight line is applied. Although the 3D scanning platform offers a new quality of crime scene documentation with BPA, some of the limitations of the technique are also mentioned. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. The Analysis of Heterogeneous Text Documents with the Help of the Computer Program NUD*IST

    Directory of Open Access Journals (Sweden)

    Christine Plaß

    2000-12-01

    Full Text Available On the basis of a current research project we discuss the use of the computer program NUD*IST for the analysis and archiving of qualitative documents. Our project examines the social evaluation of spectacular criminal offenses and we identify, digitize and analyze documents from the entire 20th century. Since public and scientific discourses are examined, the data of the project are extraordinarily heterogeneous: scientific publications, court records, newspaper reports, and administrative documents. We want to show how to transfer general questions into a systematic categorization with the assistance of NUD*IST. Apart from the functions, possibilities and limitations of the application of NUD*IST, concrete work procedures and difficulties encountered are described. URN: urn:nbn:de:0114-fqs0003211

  8. Analysis of Documents Published in Scopus Database on Foreign Language Learning through Mobile Learning: A Content Analysis

    Science.gov (United States)

    Uzunboylu, Huseyin; Genc, Zeynep

    2017-01-01

    The purpose of this study is to determine the recent trends in foreign language learning through mobile learning. The study was conducted employing document analysis and related content analysis among the qualitative research methodology. Through the search conducted on Scopus database with the key words "mobile learning and foreign language…

  9. Forensic intelligence applied to questioned document analysis: A model and its application against organized crime.

    Science.gov (United States)

    De Alcaraz-Fossoul, Josep; Roberts, Katherine A

    2017-07-01

    The capability of forensic sciences to fight crime, especially against organized criminal groups, becomes relevant in the recent economic downturn and the war on terrorism. In view of these societal challenges, the methods of combating crime should experience critical changes in order to improve the effectiveness and efficiency of the current resources available. It is obvious that authorities have serious difficulties combating criminal groups of transnational nature. These are characterized as well structured organizations with international connections, abundant financial resources and comprised of members with significant and diverse expertise. One common practice among organized criminal groups is the use of forged documents that allow for the commission of illegal cross-border activities. Law enforcement can target these movements to identify counterfeits and establish links between these groups. Information on document falsification can become relevant to generate forensic intelligence and to design new strategies against criminal activities of this nature and magnitude. This article discusses a methodology for improving the development of forensic intelligence in the discipline of questioned document analysis. More specifically, it focuses on document forgeries and falsification types used by criminal groups. It also describes the structure of international criminal organizations that use document counterfeits as means to conduct unlawful activities. The model presented is partially based on practical applications of the system that have resulted in satisfactory outcomes in our laboratory. Copyright © 2017 The Chartered Society of Forensic Sciences. Published by Elsevier B.V. All rights reserved.

  10. Analysis of Standards and Specific Documentation about Equipment of Dimensional Metrology

    Science.gov (United States)

    Martin, M. J.; Flores, I.; Sebastian, M. A.

    2009-11-01

    Currently the certification of quality systems and accreditation of laboratories for metrology and testing are activities of great interest within the framework of advanced production systems. In this context, the availability of standardized documents, complete and efficient as well as specific documents edited by agencies with experience in this field, is especially important to obtain better results and lower costs. This work tries to establish the foundations to evaluate a documental system about equipment of Dimensional Metrology. An integrated and complete system does not exist in international field, so the Spanish case will be analyzed as example to the general study. In this paper we consider three types of instruments commonly used in the field of Dimensional Metrology (vernier calliper, micrometer calliper and mechanical dial gauge) and are passed to analyze the contents of UNE standards that affect them directly, and the two collections of documents produced and edited by the Centro Español de Metrología (CEM), such as "calibration procedures" and "use manuals." Given the results of this analysis, a discussion on the metrological characteristics of the contents of the document in question is developed and recommendations for their use and improvement are proposed.

  11. Electronically signed documents in health care--analysis and assessment of data formats and transformation.

    Science.gov (United States)

    Hollerbach, A; Brandner, R; Bess, A; Schmücker, R; Bergh, B

    2005-01-01

    Our objectives were to analyze and assess data formats for their suitability for conclusive and secure long-term archiving and to develop a concept for legally secure transformation of electronically signed documents that are not available in data formats appropriate for long-term archiving. On the basis of literature review and Internet searches we developed general evaluation criteria to assess data formats with regard to their suitability for conclusive and secure long-term archiving. The assessment of data formats refers to format specifications and available literature. For the analyses of the transformation of signed documents we analyzed legal requirements on the basis of laws and ordinances as well as technical requirements by means of literature reviews, Internet searches and technical specifications. The following evaluation criteria are suited for this kind of assessment of data formats: transparency and standardization, stability, presentation and security. According to our assessment the following data formats are most suitable for conclusive and secure long-term archiving: PDF for formatted and unstructured text documents, XML for markup languages, TIFF for images in general, DICOM for medical images and S/MIME for the storage of e-mail. To transform electronically signed documents we propose an elementary procedure and universal basic model in form of an XML schema definition that includes the necessary legal and technical information. If electronic documents are to replace paper-based documents in patient records, they have to conform to the criteria for secure long-term archiving. The analyzed data formats are to be extended by mechanisms to guarantee the long-term security of electronic signatures. To transform large quantities of documents in a legally secure way, our basic model has to be extended for automated procedures.

  12. General principles taken into account in France for the use of systems in the operating documents for accidental situations (including severe accidents) on PWR plants

    International Nuclear Information System (INIS)

    Guieu, S.; Soldermann, R.

    1991-01-01

    The paper describes the scope of operating documents with allowance for the division of operating conditions into the following main fields: design basis operating conditions, complementary operating conditions, operating conditions not considered as being plausible. General approach to the choice of systems to be used for an accidental situation and the severe accident action guide, providing the operator with a definition of specific actions, are discussed, as well as checking the appropriateness of the systems used

  13. Supporting documents for LLL area 27 (410 area) safety analysis reports, Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    Odell, B. N. [comp.

    1977-02-01

    The following appendices are common to the LLL Safety Analysis Reports Nevada Test Site and are included here as supporting documents to those reports: Environmental Monitoring Report for the Nevada Test Site and Other Test Areas Used for Underground Nuclear Detonations, U. S. Environmental Protection Agency, Las Vegas, Rept. EMSL-LV-539-4 (1976); Selected Census Information Around the Nevada Test Site, U. S. Environmental Protection Agency, Las Vegas, Rept. NERC-LV-539-8 (1973); W. J. Hannon and H. L. McKague, An Examination of the Geology and Seismology Associated with Area 410 at the Nevada Test Site, Lawrence Livermore Laboratory, Livermore, Rept. UCRL-51830 (1975); K. R. Peterson, Diffusion Climatology for Hypothetical Accidents in Area 410 of the Nevada Test Site, Lawrence Livermore Laboratory, Livermore, Rept. UCRL-52074 (1976); J. R. McDonald, J. E. Minor, and K. C. Mehta, Development of a Design Basis Tornado and Structural Design Criteria for the Nevada Test Site, Nevada, Lawrence Livermore Laboratory, Livermore, Rept. UCRL-13668 (1975); A. E. Stevenson, Impact Tests of Wind-Borne Wooden Missiles, Sandia Laboratories, Tonopah, Rept. SAND 76-0407 (1976); and Hydrology of the 410 Area (Area 27) at the Nevada Test Site.

  14. Corporate Social Responsibility programs of Big Food in Australia: a content analysis of industry documents.

    Science.gov (United States)

    Richards, Zoe; Thomas, Samantha L; Randle, Melanie; Pettigrew, Simone

    2015-12-01

    To examine Corporate Social Responsibility (CSR) tactics by identifying the key characteristics of CSR strategies as described in the corporate documents of selected 'Big Food' companies. A mixed methods content analysis was used to analyse the information contained on Australian Big Food company websites. Data sources included company CSR reports and web-based content that related to CSR initiatives employed in Australia. A total of 256 CSR activities were identified across six organisations. Of these, the majority related to the categories of environment (30.5%), responsibility to consumers (25.0%) or community (19.5%). Big Food companies appear to be using CSR activities to: 1) build brand image through initiatives associated with the environment and responsibility to consumers; 2) target parents and children through community activities; and 3) align themselves with respected organisations and events in an effort to transfer their positive image attributes to their own brands. Results highlight the type of CSR strategies Big Food companies are employing. These findings serve as a guide to mapping and monitoring CSR as a specific form of marketing. © 2015 Public Health Association of Australia.

  15. A study on family-school cooperation based on an analysis of school documentation

    Directory of Open Access Journals (Sweden)

    Polovina Nada

    2007-01-01

    Full Text Available Family-school cooperation is a very complex process that can be studied at different levels in a number of different ways. This study has covered only some aspects of cooperation between parents and teachers, based on school documentation of a Belgrade elementary school. The study covered analyses of 60 Attendance Registers pertaining to 60 classes with 1289 students from Grade 1 through Grade 8 during an academic year. The unit of analysis included: parents attendance at PTA meetings and individual meetings between parents and teachers. In addition to the frequency of parents’ visits to school, the relationship between such registered parents' visits and overall academic performance, grades in conduct, excused and unexcused absence from classes were also considered. The research findings indicated interference between development factors (attitude change in parent-child relationship and growing-up and parents’ informal "theory of critical grades" i.e. transitional processes in schooling. The findings confirmed that parents’ individual visits to school were mainly meant to offer an excuse for the student’s absence from school, while attendance at PTA meetings was linked to poor grades in conduct and missed classes (both excused and unexcused. The findings also showed that parents pursued visiting strategies which were pragmatic, less time-consuming and less emotionally draining ones. The closing part refers to discussions on practical use of the study and possible further research. .

  16. Fourier transform hyperspectral visible imaging and the nondestructive analysis of potentially fraudulent documents.

    Science.gov (United States)

    Brauns, Eric B; Dyer, R Brian

    2006-08-01

    The work presented in this paper details the design and performance characteristics of a new hyperspectral visible imaging technique. Rather than using optical filters or a dispersing element, this design implements Fourier transform spectroscopy to achieve spectral discrimination. One potentially powerful application of this new technology is the non-destructive analysis and authentication of written and printed documents. Document samples were prepared using red, blue, and black inks. The samples were later altered using a different ink of the same color. While the alterations are undetectable to the naked eye, the alterations involving the blue and black inks were easily detected when the spectrally resolved images were viewed. Analysis of the sample using the red inks was unsuccessful. A 2004 series 20 US dollars bill was imaged to demonstrate the application to document authentication. The results argue that counterfeit detection and quality control during printing are plausible applications of Fourier transform hyperspectral visible imaging. All of the images were subjected to fuzzy c-means cluster analysis in an effort to objectively analyze and automate image analysis. Our results show that cluster analysis can distinguish image features that have remarkably similar visible transmission spectra.

  17. SUSHI: an exquisite recipe for fully documented, reproducible and reusable NGS data analysis.

    Science.gov (United States)

    Hatakeyama, Masaomi; Opitz, Lennart; Russo, Giancarlo; Qi, Weihong; Schlapbach, Ralph; Rehrauer, Hubert

    2016-06-02

    Next generation sequencing (NGS) produces massive datasets consisting of billions of reads and up to thousands of samples. Subsequent bioinformatic analysis is typically done with the help of open source tools, where each application performs a single step towards the final result. This situation leaves the bioinformaticians with the tasks to combine the tools, manage the data files and meta-information, document the analysis, and ensure reproducibility. We present SUSHI, an agile data analysis framework that relieves bioinformaticians from the administrative challenges of their data analysis. SUSHI lets users build reproducible data analysis workflows from individual applications and manages the input data, the parameters, meta-information with user-driven semantics, and the job scripts. As distinguishing features, SUSHI provides an expert command line interface as well as a convenient web interface to run bioinformatics tools. SUSHI datasets are self-contained and self-documented on the file system. This makes them fully reproducible and ready to be shared. With the associated meta-information being formatted as plain text tables, the datasets can be readily further analyzed and interpreted outside SUSHI. SUSHI provides an exquisite recipe for analysing NGS data. By following the SUSHI recipe, SUSHI makes data analysis straightforward and takes care of documentation and administration tasks. Thus, the user can fully dedicate his time to the analysis itself. SUSHI is suitable for use by bioinformaticians as well as life science researchers. It is targeted for, but by no means constrained to, NGS data analysis. Our SUSHI instance is in productive use and has served as data analysis interface for more than 1000 data analysis projects. SUSHI source code as well as a demo server are freely available.

  18. Maury Documentation

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Supporting documentation for the Maury Collection of marine observations. Includes explanations from Maury himself, as well as guides and descriptions by the U.S....

  19. In situ analysis of historical documents through a portable system of X RF

    International Nuclear Information System (INIS)

    Ruvalcaba S, J.L.; Gonzalez T, C.

    2005-01-01

    From the analysis of the documents and ancient books, the chronology of documents, the use of materials (paper, parchment, inks, pigments) and deterioration, among others aspects may be determined. Usually it is difficult to bring the object to the laboratory for analysis and it is not possible to sample (even small portions). Due to the importance of the documents characterization, it is necessary to carry out a diagnostic analysis at the library in order to establish the general nature of the materials (organic or inorganic), the main composition of inks and pigments, actual and possible deterioration. From this point of view, X-ray fluorescence analysis (X RF) with a portable system, may be used for quick non-destructive elemental composition determinations. A X RF system was specially developed at the Physics Institute (UNAM) for these purposes and it may be used out of the laboratory in libraries and museums. In this work, our X RF methodology is described and the study of inks of manuscripts from 15 Th and 16 Th centuries belonging to the National Anthropology and History Library is presented. (Author)

  20. Final safety analysis report for the Galileo Mission: Volume 2: Book 1, Accident model document

    Energy Technology Data Exchange (ETDEWEB)

    1988-12-15

    The Accident Model Document (AMD) is the second volume of the three volume Final Safety Analysis Report (FSAR) for the Galileo outer planetary space science mission. This mission employs Radioisotope Thermoelectric Generators (RTGs) as the prime electrical power sources for the spacecraft. Galileo will be launched into Earth orbit using the Space Shuttle and will use the Inertial Upper Stage (IUS) booster to place the spacecraft into an Earth escape trajectory. The RTG's employ silicon-germanium thermoelectric couples to produce electricity from the heat energy that results from the decay of the radioisotope fuel, Plutonium-238, used in the RTG heat source. The heat source configuration used in the RTG's is termed General Purpose Heat Source (GPHS), and the RTG's are designated GPHS-RTGs. The use of radioactive material in these missions necessitates evaluations of the radiological risks that may be encountered by launch complex personnel as well as by the Earth's general population resulting from postulated malfunctions or failures occurring in the mission operations. The FSAR presents the results of a rigorous safety assessment, including substantial analyses and testing, of the launch and deployment of the RTGs for the Galileo mission. This AMD is a summary of the potential accident and failure sequences which might result in fuel release, the analysis and testing methods employed, and the predicted source terms. Each source term consists of a quantity of fuel released, the location of release and the physical characteristics of the fuel released. Each source term has an associated probability of occurrence. 27 figs., 11 tabs.

  1. The Intersectoral Collaboration Document for Cancer Risk Factors Reduction: Method and Stakeholder Analysis

    Directory of Open Access Journals (Sweden)

    Ali-Asghar Kolahi

    2016-03-01

    Full Text Available Background and Objective: Cancers are one of the most important public health issues and the third leading cause of mortality after cardiovascular diseases and injuries in Iran. The most common cancers reported in the recent years have been included skin, stomach, breast, colon, bladder, leukemia, and esophagus respectively. Control of cancer as one of the three main health system priorities of Iran, needs a specific roadmap and clear task definition for involved organizations. This study provides stakeholder analysis include determining the roles of Ministry of Health and Medical Education as the custodian of the national health and the duties of other beneficiary organizations to reduce the risk of cancer for cooperation with a scientific approach and systematic methodology.Materials and Methods: This health system research project was performed by participation of Social Determinants of Health Research Center of Shahid Beheshti University of Medical Sciences, Office of the Non-Communicable Diseases of the Ministry of Health and Medical Education and other stakeholders in 2013. At first, the strategic committee was established and the stakeholders were identified and analyzed. Then the quantitative data were collected by searching in national database concern incidence, prevalence, and burden of all types of cancers. At the last with the qualitative approach, a systematic review of the studies, documents and reports was conducted as well as conversing for the national strategic plans of Iran and other countries and the experts’ views regarding management of the cancer risk factors. In practice, role and responsibilities of each stakeholder were practically analyzed. Then the risk factors identified and the effective evidence-based interventions were determined for each cancer and finally the role of the Ministry of Health were set as the responsible or co-worker and also the role of the other organizations separately clarified in each

  2. Comparison of approaches for mobile document image analysis using server supported smartphones

    Science.gov (United States)

    Ozarslan, Suleyman; Eren, P. Erhan

    2014-03-01

    With the recent advances in mobile technologies, new capabilities are emerging, such as mobile document image analysis. However, mobile phones are still less powerful than servers, and they have some resource limitations. One approach to overcome these limitations is performing resource-intensive processes of the application on remote servers. In mobile document image analysis, the most resource consuming process is the Optical Character Recognition (OCR) process, which is used to extract text in mobile phone captured images. In this study, our goal is to compare the in-phone and the remote server processing approaches for mobile document image analysis in order to explore their trade-offs. For the inphone approach, all processes required for mobile document image analysis run on the mobile phone. On the other hand, in the remote-server approach, core OCR process runs on the remote server and other processes run on the mobile phone. Results of the experiments show that the remote server approach is considerably faster than the in-phone approach in terms of OCR time, but adds extra delays such as network delay. Since compression and downscaling of images significantly reduce file sizes and extra delays, the remote server approach overall outperforms the in-phone approach in terms of selected speed and correct recognition metrics, if the gain in OCR time compensates for the extra delays. According to the results of the experiments, using the most preferable settings, the remote server approach performs better than the in-phone approach in terms of speed and acceptable correct recognition metrics.

  3. Meaningful participation for children in the Dutch child protection system: A critical analysis of relevant provisions in policy documents.

    Science.gov (United States)

    Bouma, Helen; López López, Mónica; Knorth, Erik J; Grietens, Hans

    2018-05-01

    Policymakers are increasingly focusing on the participation of children in the child protection system (CPS). However, research shows that actual practice still needs to be improved. Embedding children's participation in legislation and policy documents is one important prerequisite for achieving meaningful participation in child protection practice. In this study, the participation of children in the Dutch CPS under the new Youth Act 2015 is critically analyzed. National legislation and policy documents were studied using a model of "meaningful participation" based on article 12 of the UNCRC. Results show that the idea of children's participation is deeply embedded in the current Dutch CPS. However, Dutch policy documents do not fully cover the three dimensions of what is considered to be meaningful participation for children: informing, hearing, and involving. Furthermore, children's participation differs among the organizations included in the child protection chain. A clear overall policy concerning the participation of children in the Dutch CPS is lacking. The conclusions of this critical analysis of policy documents and the framework of meaningful participation presented may provide a basis for the embedding of meaningful participation for children in child protection systems of other countries. Copyright © 2018 Elsevier Ltd. All rights reserved.

  4. Expert evaluation of technical documentation 'Analysis of structures of blocks 1-6 of the Kozloduy NPP for the seismic effect of local earthquakes'

    International Nuclear Information System (INIS)

    Jurukovski, D.

    1999-01-01

    The subject of this expert evaluation is the technical documentation 'Analysis of structures of blocks 1-6 of the Kozloduy NPP for the seismic effect of local earthquakes'. It includes reviews of expert evaluations of the parameters of local seismic effects and the analysis of floor response spectra for blocks 3, 4, 5 and 6 at Kozloduy NPP

  5. rBEFdata: documenting data exchange and analysis for a collaborative data management platform.

    Science.gov (United States)

    Pfaff, Claas-Thido; König-Ries, Birgitta; Lang, Anne C; Ratcliffe, Sophia; Wirth, Christian; Man, Xingxing; Nadrowski, Karin

    2015-07-01

    We are witnessing a growing gap separating primary research data from derived data products presented as knowledge in publications. Although journals today more often require the underlying data products used to derive the results as a prerequisite for a publication, the important link to the primary data is lost. However, documenting the postprocessing steps of data linking, the primary data with derived data products has the potential to increase the accuracy and the reproducibility of scientific findings significantly. Here, we introduce the rBEFdata R package as companion to the collaborative data management platform BEFdata. The R package provides programmatic access to features of the platform. It allows to search for data and integrates the search with external thesauri to improve the data discovery. It allows to download and import data and metadata into R for analysis. A batched download is available as well which works along a paper proposal mechanism implemented by BEFdata. This feature of BEFdata allows to group primary data and metadata and streamlines discussions and collaborations revolving around a certain research idea. The upload functionality of the R package in combination with the paper proposal mechanism of the portal allows to attach derived data products and scripts directly from R, thus addressing major aspects of documenting data postprocessing. We present the core features of the rBEFdata R package along an ecological analysis example and further discuss the potential of postprocessing documentation for data, linking primary data with derived data products and knowledge.

  6. Too much information? A document analysis of sport safety resources from key organisations

    Science.gov (United States)

    Finch, Caroline F

    2016-01-01

    Objectives The field of sport injury prevention has seen a marked increase in published research in recent years, with concomitant proliferation of lay sport safety resources, such as policies, fact sheets and posters. The aim of this study was to catalogue and categorise the number, type and topic focus of sport safety resources from a representative set of key organisations. Design Cataloguing and qualitative document analysis of resources available from the websites of six stakeholder organisations in Australia. Setting This study was part of a larger investigation, the National Guidance for Australian Football Partnerships and Safety (NoGAPS) project. Participants The NoGAPS study provided the context for a purposive sampling of six organisations involved in the promotion of safety in Australian football. These partners are recognised as being highly representative of organisations at national and state level that reflect similarly in their goals around sport safety promotion in Australia. Results The catalogue comprised 284 resources. More of the practical and less prescriptive types of resources, such as fact sheets, than formal policies were found. Resources for the prevention of physical injuries were the predominant sport safety issue addressed, with risk management, environmental issues and social behaviours comprising other categories. Duplication of resources for specific safety issues, within and across organisations, was found. Conclusions People working within sport settings have access to a proliferation of resources, which creates a potential rivalry for sourcing of injury prevention information. Important issues that are likely to influence the uptake of safety advice by the general sporting public include the sheer number of resources available, and the overlap and duplication of resources addressing the same issues. The existence of a large number of resources from reputable organisations does not mean that they are necessarily evidence based

  7. Guidance document for preparing water sampling and analysis plans for UMTRA Project sites. Revision 1

    International Nuclear Information System (INIS)

    1995-09-01

    A water sampling and analysis plan (WSAP) is prepared for each Uranium Mill Tailings Remedial Action (UMTRA) Project site to provide the rationale for routine ground water sampling at disposal sites and former processing sites. The WSAP identifies and justifies the sampling locations, analytical parameters, detection limits, and sampling frequency for the routine ground water monitoring stations at each site. This guidance document has been prepared by the Technical Assistance Contractor (TAC) for the US Department of Energy (DOE). Its purpose is to provide a consistent technical approach for sampling and monitoring activities performed under the WSAP and to provide a consistent format for the WSAP documents. It is designed for use by the TAC in preparing WSAPs and by the DOE, US Nuclear Regulatory Commission, state and tribal agencies, other regulatory agencies, and the public in evaluating the content of WSAPS

  8. The British research evidence for recovery, papers published between 2006 and 2009 (inclusive). Part two: a review of the grey literature including book chapters and policy documents.

    Science.gov (United States)

    Stickley, T; Wright, N

    2011-05-01

    This paper is the second in a series of two which reviews the current UK evidence base for recovery in mental health. As outlined in the previous paper, over the last 4 years a vast amount has written about recovery in mental health (approximately 60% of all articles). Whereas the first review focused on the peer-reviewed evidence; this paper specifically focuses on the grey/non-peer-reviewed literature. In total, our search strategy yielded the following: 3 books, a further 11 book chapters, 12 papers, 6 policy documents and 3 publications from voluntary sector organizations. Each group of publications was analysed for content, and they are discursively presented by publication group. The findings are then presented as themes in the discussion section. The themes are: social, historical and political critique; philosophy of hope for the individual; individual identity and narrative; models and guidance for mental health practice. We conclude that there is a need for both empirical research into recovery and a clearer theoretical exposition of the concept. © 2010 Blackwell Publishing.

  9. Understanding Factors Contributing to Inappropriate Critical Care: A Mixed-Methods Analysis of Medical Record Documentation.

    Science.gov (United States)

    Neville, Thanh H; Tarn, Derjung M; Yamamoto, Myrtle; Garber, Bryan J; Wenger, Neil S

    2017-11-01

    Factors leading to inappropriate critical care, that is treatment that should not be provided because it does not offer the patient meaningful benefit, have not been rigorously characterized. We explored medical record documentation about patients who received inappropriate critical care and those who received appropriate critical care to examine factors associated with the provision of inappropriate treatment. Medical records were abstracted from 123 patients who were assessed as receiving inappropriate treatment and 66 patients who were assessed as receiving appropriate treatment but died within six months of intensive care unit (ICU) admission. We used mixed methods combining qualitative analysis of medical record documentation with multivariable analysis to examine the relationship between patient and communication factors and the receipt of inappropriate treatment, and present these within a conceptual model. One academic health system. Medical records revealed 21 themes pertaining to prognosis and factors influencing treatment aggressiveness. Four themes were independently associated with patients receiving inappropriate treatment according to physicians. When decision making was not guided by physicians (odds ratio [OR] 3.76, confidence interval [95% CI] 1.21-11.70) or was delayed by patient/family (OR 4.52, 95% CI 1.69-12.04), patients were more likely to receive inappropriate treatment. Documented communication about goals of care (OR 0.29, 95% CI 0.10-0.84) and patient's preferences driving decision making (OR 0.02, 95% CI 0.00-0.27) were associated with lower odds of receiving inappropriate treatment. Medical record documentation suggests that inappropriate treatment occurs in the setting of communication and decision-making patterns that may be amenable to intervention.

  10. Status of High Flux Isotope Reactor (HFIR) post-restart safety analysis and documentation upgrades

    International Nuclear Information System (INIS)

    Cook, D.H.; Radcliff, T.D.; Rothrock, R.B.; Schreiber, R.E.

    1990-01-01

    The High Flux Isotope Reactor (HFIR), an experimental reactor located at the Oak Ridge National Laboratory (ORNL) and operated for the US Department of Energy by Martin Marietta Energy Systems, was shut down in November, 1986 after the discovery of unexpected neutron embrittlement of the reactor vessel. The reactor was restarted in April, 1989, following an extensive review by DOE and ORNL of the HFIR design, safety, operation, maintenance and management, and the implementation of several upgrades to HFIR safety-related hardware, analyses, documents and procedures. This included establishing new operating conditions to provide added margin against pressure vessel failure, as well as the addition, or upgrading, of specific safety-related hardware. This paper summarizes the status of some of the follow-on (post-restart) activities which are currently in progress, and which will result in a comprehensive set of safety analyses and documentation for the HFIR, comparable with current practice in commercial nuclear power plants. 8 refs

  11. Term Analysis – Improving the Quality of Learning and Application Documents in Engineering Design

    Directory of Open Access Journals (Sweden)

    S. Weiss

    2006-01-01

    Full Text Available Conceptual homogeneity is one determinant of the quality of text documents. A concept remains the same if the words used (termini change [1, 2]. In other words, termini can vary while the concept retains the same meaning. Human beings are able to handle concepts and termini because of their semantic network, which is able to connect termini to the actual context and thus identify the adequate meaning of the termini. Problems could arise when humans have to learn new content and correspondingly new concepts. Since the content is basically imparted by text via particular termini, it is a challenge to establish the right concept from the text with the termini. A term might be known, but have a different meaning [3, 4]. Therefore, it is very important to build up the correct understanding of concepts within a text. This is only possible when concepts are explained by the right termini, within an adequate context, and above all, homogeneously. So, when setting up or using text documents for teaching or application, it is essential to provide concept homogeneity.Understandably, the quality of documents is, ceteris paribus, reciprocally proportional to variations of termini. Therefore, an analysis of variations of termini could form a basis for specific improvement of conceptual homogeneity.Consequently, an exposition of variations of termini as control and improvement parameters is carried out in this investigation. This paper describes the functionality and the profit of a tool called TermAnalysis.It also outlines the margins, typeface and other vital specifications necessary for authors preparing camera-ready papers for submission to the 5th International Conference on Advanced Engineering Design. The aim of this paper is to ensure that all readers are clear as to the uniformity required by the organizing committee and to ensure that readers’ papers will be accepted as camera-ready for the conference.TermAnalysis is a software tool developed

  12. Application programming interface document for the modernized Transient Reactor Analysis Code (TRAC-M)

    International Nuclear Information System (INIS)

    Mahaffy, J.; Boyack, B.E.; Steinke, R.G.

    1998-05-01

    The objective of this document is to ease the task of adding new system components to the Transient Reactor Analysis Code (TRAC) or altering old ones. Sufficient information is provided to permit replacement or modification of physical models and correlations. Within TRAC, information is passed at two levels. At the upper level, information is passed by system-wide and component-specific data modules at and above the level of component subroutines. At the lower level, information is passed through a combination of module-based data structures and argument lists. This document describes the basic mechanics involved in the flow of information within the code. The discussion of interfaces in the body of this document has been kept to a general level to highlight key considerations. The appendices cover instructions for obtaining a detailed list of variables used to communicate in each subprogram, definitions and locations of key variables, and proposed improvements to intercomponent interfaces that are not available in the first level of code modernization

  13. Internationalization Impact on PhD Training Policy in Russia: Insights from The Comparative Document Analysis

    Directory of Open Access Journals (Sweden)

    Oksana Chigisheva

    2017-09-01

    Full Text Available The relevance of the study is due to the need for an objective picture of the Russian third level tertiary education transformation driven by internationalization issues and global trends in education. The article provides an analytical comparative review of the official documents related to the main phases of education reform in Russia and focuses on the system of PhD training which has undergone significant reorganization in recent years. A series of alterations introduced into the theory and practice of postgraduate education in Russia are traced in regulatory documents and interpreted in terms of growing internationalization demand. Possible implications for further development of the research human potential in Russia are being discussed. The method of comparative document analysis produces the best possible insight into the subject. The findings of the study contribute to the understanding of current challenges facing the system of doctoral studies in Russia and lead to certain conclusions on the transformation of educational policy in relation to PhD training under the influence of internationalization agenda.

  14. Analysis of the recent international documents toward inclusive education of children with disabilities

    Directory of Open Access Journals (Sweden)

    Tabatabaie Minou

    2012-01-01

    Full Text Available Analysis of various international documents clearly suggests that international documents have provided a significantmotivation to efforts undertaken at the national level about education of children with disabilities. UN Convention on theRights of the Child imposed a requirement for radical changes to traditional approaches to provision made for children withdisabilities. One year later, the 1990 World Conference on Education for all focused attention on a much broader range ofchildren with disabilities who may be excluded from or marginalized within education systems. Its development has involveda series of stages during which education systems have explored different ways of responding to children with disabilities andothers who experience difficulties in learning. This conference declared the inclusive education is regarded as the only meansto achieve the goal of "Education for All". This trend was reaffirmed by next international documents. And finally, accordingto the article 24 of the Convention on the rights of persons with disabilities, disabled persons should be able to accessgeneral tertiary education, vocational training, adult education and lifelong learning without discrimination and on an equalbasis with others through reasonable accommodation of their disabilities. All of these documents played an important role inbringing the attention on to children with disabilities, especially on education as a vehicle for integration and empowerment.This research examines the new international trends occurring regarding the education of children with disabilities and finallyresults that the new trends show a movement from special education to inclusive education and moving from seclusion toinclusion and provide that solutions must focus on prevention, cure and steps to make these children as normal as possible.In this regard, States must ensure the full realization of all human rights and fundamental freedoms for all disabled people,on an

  15. 17 CFR 240.15g-100 - Schedule 15G-Information to be included in the document distributed pursuant to 17 CFR 240.15g-2.

    Science.gov (United States)

    2010-04-01

    ... of investing in penny stocks. Please read it carefully before you agree to purchase or sell a penny... to accurately price. Investors in penny stock should be prepared for the possibility that they may... securities—including penny stocks—is available on the SEC's Web site at http://www.sec.gov/investor/pubs...

  16. Transnational tobacco company interests in smokeless tobacco in Europe: analysis of internal industry documents and contemporary industry materials.

    Directory of Open Access Journals (Sweden)

    Silvy Peeters

    Full Text Available European Union (EU legislation bans the sale of snus, a smokeless tobacco (SLT which is considerably less harmful than smoking, in all EU countries other than Sweden. To inform the current review of this legislation, this paper aims to explore transnational tobacco company (TTC interests in SLT and pure nicotine in Europe from the 1970s to the present, comparing them with TTCs' public claims of support for harm reduction.Internal tobacco industry documents (in total 416 documents dating from 1971 to 2009, obtained via searching the online Legacy Tobacco Documents Library, were analysed using a hermeneutic approach. This library comprises documents obtained via litigation in the US and does not include documents from Imperial Tobacco, Japan Tobacco International, or Swedish Match. To help overcome this limitation and provide more recent data, we triangulated our documentary findings with contemporary documentation including TTC investor presentations. The analysis demonstrates that British American Tobacco explored SLT opportunities in Europe from 1971 driven by regulatory threats and health concerns, both likely to impact cigarette sales negatively, and the potential to create a new form of tobacco use among those no longer interested in taking up smoking. Young people were a key target. TTCs did not, however, make SLT investments until 2002, a time when EU cigarette volumes started declining, smoke-free legislation was being introduced, and public health became interested in harm reduction. All TTCs have now invested in snus (and recently in pure nicotine, yet both early and recent snus test markets appear to have failed, and little evidence was found in TTCs' corporate materials that snus is central to their business strategy.There is clear evidence that BAT's early interest in introducing SLT in Europe was based on the potential for creating an alternative form of tobacco use in light of declining cigarette sales and social restrictions on

  17. Transnational tobacco company interests in smokeless tobacco in Europe: analysis of internal industry documents and contemporary industry materials.

    Science.gov (United States)

    Peeters, Silvy; Gilmore, Anna B

    2013-01-01

    European Union (EU) legislation bans the sale of snus, a smokeless tobacco (SLT) which is considerably less harmful than smoking, in all EU countries other than Sweden. To inform the current review of this legislation, this paper aims to explore transnational tobacco company (TTC) interests in SLT and pure nicotine in Europe from the 1970s to the present, comparing them with TTCs' public claims of support for harm reduction. Internal tobacco industry documents (in total 416 documents dating from 1971 to 2009), obtained via searching the online Legacy Tobacco Documents Library, were analysed using a hermeneutic approach. This library comprises documents obtained via litigation in the US and does not include documents from Imperial Tobacco, Japan Tobacco International, or Swedish Match. To help overcome this limitation and provide more recent data, we triangulated our documentary findings with contemporary documentation including TTC investor presentations. The analysis demonstrates that British American Tobacco explored SLT opportunities in Europe from 1971 driven by regulatory threats and health concerns, both likely to impact cigarette sales negatively, and the potential to create a new form of tobacco use among those no longer interested in taking up smoking. Young people were a key target. TTCs did not, however, make SLT investments until 2002, a time when EU cigarette volumes started declining, smoke-free legislation was being introduced, and public health became interested in harm reduction. All TTCs have now invested in snus (and recently in pure nicotine), yet both early and recent snus test markets appear to have failed, and little evidence was found in TTCs' corporate materials that snus is central to their business strategy. There is clear evidence that BAT's early interest in introducing SLT in Europe was based on the potential for creating an alternative form of tobacco use in light of declining cigarette sales and social restrictions on smoking, with

  18. Transnational Tobacco Company Interests in Smokeless Tobacco in Europe: Analysis of Internal Industry Documents and Contemporary Industry Materials

    Science.gov (United States)

    Peeters, Silvy; Gilmore, Anna B.

    2013-01-01

    Background European Union (EU) legislation bans the sale of snus, a smokeless tobacco (SLT) which is considerably less harmful than smoking, in all EU countries other than Sweden. To inform the current review of this legislation, this paper aims to explore transnational tobacco company (TTC) interests in SLT and pure nicotine in Europe from the 1970s to the present, comparing them with TTCs' public claims of support for harm reduction. Methods and Results Internal tobacco industry documents (in total 416 documents dating from 1971 to 2009), obtained via searching the online Legacy Tobacco Documents Library, were analysed using a hermeneutic approach. This library comprises documents obtained via litigation in the US and does not include documents from Imperial Tobacco, Japan Tobacco International, or Swedish Match. To help overcome this limitation and provide more recent data, we triangulated our documentary findings with contemporary documentation including TTC investor presentations. The analysis demonstrates that British American Tobacco explored SLT opportunities in Europe from 1971 driven by regulatory threats and health concerns, both likely to impact cigarette sales negatively, and the potential to create a new form of tobacco use among those no longer interested in taking up smoking. Young people were a key target. TTCs did not, however, make SLT investments until 2002, a time when EU cigarette volumes started declining, smoke-free legislation was being introduced, and public health became interested in harm reduction. All TTCs have now invested in snus (and recently in pure nicotine), yet both early and recent snus test markets appear to have failed, and little evidence was found in TTCs' corporate materials that snus is central to their business strategy. Conclusions There is clear evidence that BAT's early interest in introducing SLT in Europe was based on the potential for creating an alternative form of tobacco use in light of declining cigarette sales

  19. Data development technical support document for the aircraft crash risk analysis methodology (ACRAM) standard

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, C.Y.; Glaser, R.E.; Mensing, R.W.; Lin, T.; Haley, T.A.; Barto, A.B.; Stutzke, M.A.

    1996-08-01

    The Aircraft Crash Risk Analysis Methodology (ACRAM) Panel has been formed by the US Department of Energy Office of Defense Programs (DOE/DP) for the purpose of developing a standard methodology for determining the risk from aircraft crashes onto DOE ground facilities. In order to accomplish this goal, the ACRAM panel has been divided into four teams, the data development team, the model evaluation team, the structural analysis team, and the consequence team. Each team, consisting of at least one member of the ACRAM plus additional DOE and DOE contractor personnel, specializes in the development of the methodology assigned to that team. This report documents the work performed by the data development team and provides the technical basis for the data used by the ACRAM Standard for determining the aircraft crash frequency. This report should be used to provide the generic data needed to calculate the aircraft crash frequency into the facility under consideration as part of the process for determining the aircraft crash risk to ground facilities as given by the DOE Standard Aircraft Crash Risk Assessment Methodology (ACRAM). Some broad guidance is presented on how to obtain the needed site-specific and facility specific data but this data is not provided by this document.

  20. Data development technical support document for the aircraft crash risk analysis methodology (ACRAM) standard

    International Nuclear Information System (INIS)

    Kimura, C.Y.; Glaser, R.E.; Mensing, R.W.; Lin, T.; Haley, T.A.; Barto, A.B.; Stutzke, M.A.

    1996-01-01

    The Aircraft Crash Risk Analysis Methodology (ACRAM) Panel has been formed by the US Department of Energy Office of Defense Programs (DOE/DP) for the purpose of developing a standard methodology for determining the risk from aircraft crashes onto DOE ground facilities. In order to accomplish this goal, the ACRAM panel has been divided into four teams, the data development team, the model evaluation team, the structural analysis team, and the consequence team. Each team, consisting of at least one member of the ACRAM plus additional DOE and DOE contractor personnel, specializes in the development of the methodology assigned to that team. This report documents the work performed by the data development team and provides the technical basis for the data used by the ACRAM Standard for determining the aircraft crash frequency. This report should be used to provide the generic data needed to calculate the aircraft crash frequency into the facility under consideration as part of the process for determining the aircraft crash risk to ground facilities as given by the DOE Standard Aircraft Crash Risk Assessment Methodology (ACRAM). Some broad guidance is presented on how to obtain the needed site-specific and facility specific data but this data is not provided by this document

  1. Manned space flight nuclear system safety. Volume 3: Reactor system preliminary nuclear safety analysis. Part 1: Reference Design Document (RDD)

    Science.gov (United States)

    1972-01-01

    The Reference Design Document, of the Preliminary Safety Analysis Report (PSAR) - Reactor System provides the basic design and operations data used in the nuclear safety analysis of the Rector Power Module as applied to a Space Base program. A description of the power module systems, facilities, launch vehicle and mission operations, as defined in NASA Phase A Space Base studies is included. Each of two Zirconium Hydride Reactor Brayton power modules provides 50 kWe for the nominal 50 man Space Base. The INT-21 is the prime launch vehicle. Resupply to the 500 km orbit over the ten year mission is provided by the Space Shuttle. At the end of the power module lifetime (nominally five years), a reactor disposal system is deployed for boost into a 990 km high altitude (long decay time) earth orbit.

  2. Does Working Memory Training Transfer? A Meta-Analysis Including Training Conditions as Moderators

    Science.gov (United States)

    Schwaighofer, Matthias; Fischer, Frank; Bühner, Markus

    2015-01-01

    A meta-analysis was undertaken to reexamine near- and far-transfer effects following working-memory training and to consider potential moderators more systematically. Forty-seven studies with 65 group comparisons were included in the meta-analysis. Results showed near-transfer effects to short-term and working-memory skills that were sustained at…

  3. A review of the reliability analysis of LPRS including the components repairs

    International Nuclear Information System (INIS)

    Oliveira, L.F.S. de; Fleming, P.V.; Frutuoso e Melo, P.F.F.; Tayt-Sohn, L.C.

    1983-01-01

    The reliability analysis of low pressure recirculation system in its long-term recicurlation phase before 24hs is presented. The possibility of repairing the components out of the containment is included. A general revision of analysis of the short-term recirculation phase is done. (author) [pt

  4. Guidance Document - Provision of Outage Reserve Capacity for Molybdenum-99 Irradiation Services: Methodology and Economic Analysis

    International Nuclear Information System (INIS)

    Peykov, Pavel; Cameron, Ron; Westmacott, Chad

    2013-01-01

    In June 2011, the OECD Nuclear Energy Agency's (NEA) High-level Group on the Security of Supply of Medical Radioisotopes (HLG-MR) released its policy approach for ensuring a long-term secure supply of molybdenum-99 ( 99 Mo) and its decay product technetium-99m (' 99m Tc). This policy approach was developed after two years of extensive examination and analysis of the challenges facing the supply chain, and the provision of a reliable, secure supply of these important medical isotopes. The full policy approach can be found in the OECD/NEA report, The Supply of Medical Radioisotopes: The Path to Reliability (NEA, 2011). One of the key principles in the policy approach relates to the provision of outage reserve capacity (ORC) in the 99 Mo/' 99m Tc supply chain, as defined on page 7: 'Principle 2: Reserve capacity should be sourced and paid for by the supply chain. A common approach should be used to determine the amount of reserve capacity required'. This Principle follows the findings of the OECD/NEA report, The Supply of Medical Radioisotopes: An Economic Study of the Molybdenum-99 Supply Chain (NEA, 2010), which clearly demonstrated the need for excess 99 Mo production capacity, relative to demand, as some reactors may have to be shutdown unexpectedly or for extended periods. The Study also demonstrated that the pricing structure from reactors for 99 Mo irradiation services prior to the 2009-10 supply shortage was not economically sustainable, including the pricing of ORC, with the cost being subsidised by host nations. These nations have indicated a move away from subsidising production, which often benefits foreign nations or foreign companies, and therefore pricing for irradiation services must recover the full cost of production to ensure economic sustainability and a long-term secure supply. Appropriate pricing would also encourage more efficient use of the product, reducing inefficient use of 99 Mo/' 99m Tc would reduce excess production and the associated

  5. Applying a sociolinguistic model to the analysis of informed consent documents.

    Science.gov (United States)

    Granero-Molina, José; Fernández-Sola, Cayetano; Aguilera-Manrique, Gabriel

    2009-11-01

    Information on the risks and benefits related to surgical procedures is essential for patients in order to obtain their informed consent. Some disciplines, such as sociolinguistics, offer insights that are helpful for patient-professional communication in both written and oral consent. Communication difficulties become more acute when patients make decisions through an informed consent document because they may sign this with a lack of understanding and information, and consequently feel deprived of their freedom to make their choice about different treatments or surgery. This article discusses findings from documentary analysis using the sociolinguistic SPEAKING model, which was applied to the general and specific informed consent documents required for laparoscopic surgery of the bile duct at Torrecárdenas Hospital, Almería, Spain. The objective of this procedure was to identify flaws when information was provided, together with its readability, its voluntary basis, and patients' consent. The results suggest potential linguistic communication difficulties, different languages being used, cultural clashes, asymmetry of communication between professionals and patients, assignment of rights on the part of patients, and overprotection of professionals and institutions.

  6. Reading the Music and Understanding the Therapeutic Process: Documentation, Analysis and Interpretation of Improvisational Music Therapy

    Directory of Open Access Journals (Sweden)

    Deborah Parker

    2011-01-01

    Full Text Available This article is concerned primarily with the challenges of presenting clinical material from improvisational music therapy. My aim is to propose a model for the transcription of music therapy material, or “musicotherapeutic objects” (comparable to Bion’s “psychoanalytic objects”, which preserves the integrated “gestalt” of the musical experience as far as possible, whilst also supporting detailed analysis and interpretation. Unwilling to resort to use of visual documentation, but aware that many important indicators in music therapy are non-sounding, I propose a richly annotated score, where traditional music notation is integrated with graphic and verbal additions, in order to document non-sounding events. This model is illustrated within the context of a clinical case with a high functioning autistic woman. The four transcriptions, together with the original audio tracks, present significant moments during the course of music therapy, attesting to the development of the dyadic relationship, with reference to John Bowlby’s concept of a “secure base” as the most appropriate dynamic environment for therapy.

  7. Evaluation of Rapid Stain IDentification (RSID™ Reader System for Analysis and Documentation of RSID™ Tests

    Directory of Open Access Journals (Sweden)

    Pravatchai W. Boonlayangoor

    2013-08-01

    Full Text Available The ability to detect the presence of body fluids is a crucial first step in documenting and processing forensic evidence. The Rapid Stain IDentification (RSID™ tests for blood, saliva, semen and urine are lateral flow immunochromatographic strip tests specifically designed for forensic use. Like most lateral flow strips, the membrane components of the test are enclosed in a molded plastic cassette with a sample well and an observation window. No specialized equipment is required to use these tests or to score the results seen in the observation window; however, the utility of these tests can be enhanced if an electronic record of the test results can be obtained, preferably by a small hand-held device that could be used in the field under low light conditions. Such a device should also be able to “read” the lateral flow strips and accurately record the results of the test as either positive, i.e., the body fluid was detected, or negative, i.e., the body fluid was not detected. Here we describe the RSID™ Reader System—a ruggedized strip test reader unit that allows analysis and documentation of RSID™ lateral flow strip tests using pre-configured settings, and show that the RSID™ Reader can accurately and reproducibly report and record correct results from RSID™ blood, saliva, semen, and urine tests.

  8. CAED Document Repository

    Science.gov (United States)

    Compliance Assurance and Enforcement Division Document Repository (CAEDDOCRESP) provides internal and external access of Inspection Records, Enforcement Actions, and National Environmental Protection Act (NEPA) documents to all CAED staff. The respository will also include supporting documents, images, etc.

  9. Market Analysis and Consumer Impacts Source Document. Part III. Consumer Behavior and Attitudes Toward Fuel Efficient Vehicles

    Science.gov (United States)

    1980-12-01

    This source document on motor vehicle market analysis and consumer impacts consists of three parts. Part III consists of studies and reviews on: consumer awareness of fuel efficiency issues; consumer acceptance of fuel efficient vehicles; car size ch...

  10. [Photography as analysis document, body and medicine: theory, method and criticism--the experience of Museo Nacional de Medicina Enrique Laval].

    Science.gov (United States)

    Robinson, César Leyton; Caballero, Andrés Díaz

    2007-01-01

    This article is an experimental methodological reflection on the use of medical images as useful documents for constructing the history of medicine. A method is used that is based on guidelines or analysis topics that include different ways of viewing documents, from aesthetic, technical, social and political theories to historical and medical thinking. Some exercises are also included that enhance the proposal for the reader: rediscovering the worlds in society that harbor these medical photographical archives to obtain a new theoretical approach to the construction of the history of medical science.

  11. Applications for electronic documents

    International Nuclear Information System (INIS)

    Beitel, G.A.

    1995-01-01

    This paper discusses the application of electronic media to documents, specifically Safety Analysis Reports (SARs), prepared for Environmental Restoration and Waste Management (ER ampersand WM) programs being conducted for the Department of Energy (DOE) at the Idaho National Engineering Laboratory (INEL). Efforts are underway to upgrade our document system using electronic format. To satisfy external requirements (DOE, State, and Federal), ER ampersand WM programs generate a complement of internal requirements documents including a SAR and Technical Safety Requirements along with procedures and training materials. Of interest, is the volume of information and the difficulty in handling it. A recently prepared ER ampersand WM SAR consists of 1,000 pages of text and graphics; supporting references add 10,000 pages. Other programmatic requirements documents consist of an estimated 5,000 pages plus references

  12. Canister storage building (CSB) safety analysis report phase 3: Safety analysis documentation supporting CSB construction

    International Nuclear Information System (INIS)

    Garvin, L.J.

    1997-01-01

    The Canister Storage Building (CSB) will be constructed in the 200 East Area of the U.S. Department of Energy (DOE) Hanford Site. The CSB will be used to stage and store spent nuclear fuel (SNF) removed from the Hanford Site K Basins. The objective of this chapter is to describe the characteristics of the site on which the CSB will be located. This description will support the hazard analysis and accident analyses in Chapter 3.0. The purpose of this report is to provide an evaluation of the CSB design criteria, the design's compliance with the applicable criteria, and the basis for authorization to proceed with construction of the CSB

  13. Risk D and D Rapid Prototype: Scenario Documentation and Analysis Tool

    International Nuclear Information System (INIS)

    Unwin, Stephen D.; Seiple, Timothy E.

    2009-01-01

    Report describes process and methodology associated with a rapid prototype tool for integrating project risk analysis and health and safety risk analysis for decontamination and decommissioning projects. The objective of the Decontamination and Decommissioning (D and D) Risk Management Evaluation and Work Sequencing Standardization Project under DOE EM-23 is to recommend or develop practical risk-management tools for decommissioning of nuclear facilities. PNNL has responsibility under this project for recommending or developing computer-based tools that facilitate the evaluation of risks in order to optimize the sequencing of D and D work. PNNL's approach is to adapt, augment, and integrate existing resources rather than to develop a new suite of tools. Methods for the evaluation of H and S risks associated with work in potentially hazardous environments are well-established. Several approaches exist which, collectively, are referred to as process hazard analysis (PHA). A PHA generally involves the systematic identification of accidents, exposures, and other adverse events associated with a given process or work flow. This identification process is usually achieved in a brainstorming environment or by other means of eliciting informed opinion. The likelihoods of adverse events (scenarios) and their associated consequence severities are estimated against pre-defined scales, based on which risk indices are then calculated. A similar process is encoded in various project risk software products that facilitate the quantification of schedule and cost risks associated with adverse scenarios. However, risk models do not generally capture both project risk and H and S risk. The intent of the project reported here is to produce a tool that facilitates the elicitation, characterization, and documentation of both project risk and H and S risk based on defined sequences of D and D activities. By considering alternative D and D sequences, comparison of the predicted risks can

  14. Why continuity of care needs computing--results of a quantitative document analysis.

    Science.gov (United States)

    Hübner, Ursula; Giehoff, Carsten

    2002-01-01

    With the increasing practice of early discharges from hospital continuity of care is attaining new attention. Although communication gaps including incomplete and delayed information are well known the vast majority of discharge summaries are still paperbased. The question of this study was whether The medium paperbased discharge form can be structured and complete enough to overcome the communication deficits. All 32 different types of nursing discharge forms analysed suffered from a compromise between structure, content and space. None of the forms allowed for a complete documentation of the nursing process. Only the minority of forms offered the complete set of activities of daily living to be checked. Most of the forms were designed only by one sector without any provisions for different terminologies and needs across the sectors. It is concluded that these shortcomings can only be overcome by a dynamic and flexible instrument, ideally by an electronic discharge summary.

  15. WEB NEWS DOCUMENTS CLUSTERING IN INDONESIAN LANGUAGE USING SINGULAR VALUE DECOMPOSITION-PRINCIPAL COMPONENT ANALYSIS (SVDPCA AND ANT ALGORITHMS

    Directory of Open Access Journals (Sweden)

    Arif Fadllullah

    2016-02-01

    Full Text Available Ant-based document clustering is a cluster method of measuring text documents similarity based on the shortest path between nodes (trial phase and determines the optimal clusters of sequence document similarity (dividing phase. The processing time of trial phase Ant algorithms to make document vectors is very long because of high dimensional Document-Term Matrix (DTM. In this paper, we proposed a document clustering method for optimizing dimension reduction using Singular Value Decomposition-Principal Component Analysis (SVDPCA and Ant algorithms. SVDPCA reduces size of the DTM dimensions by converting freq-term of conventional DTM to score-pc of Document-PC Matrix (DPCM. Ant algorithms creates documents clustering using the vector space model based on the dimension reduction result of DPCM. The experimental results on 506 news documents in Indonesian language demonstrated that the proposed method worked well to optimize dimension reduction up to 99.7%. We could speed up execution time efficiently of the trial phase and maintain the best F-measure achieved from experiments was 0.88 (88%.

  16. The Role of Development Agencies in Touristic Branding of Cities, A Document Analysis on Regional Plans

    Directory of Open Access Journals (Sweden)

    Emrah ÖZKUL

    2012-12-01

    Full Text Available The objective of present research is to determine the role of development agencies in which the branding of cities in the region. At research, the role of development agencies; identification of unknown tourist values, determination and improving of deficiencies, opportunities, were investigated in accordance with the agency's goals and objectives. To achieve this goal used in document analysis from qualitative research methods and Regional Plans were investigated which was published by the Development Agencies. The data obtained were subjected to descriptive analysis, in the case of some unidentified concepts by going in-depth content analysis. Despite all the advantages of having Turkey, made enough promotion of national and international level many regions in Turkey and so the tourism industry has led to overshadowed by the industrial and agricultural sectors. For this reason, development agencies determining the values of regional tourism have undertaken to task of changing perceptions of tourist consumers with their targeted projects on behalf of perform the city branding. Thus, was concluded that cities could become a center of attraction and the brand both investors and visitors.

  17. Final Safety Analysis Document for Building 693 Chemical Waste Storage Building at Lawrence Livermore National Laboratory

    International Nuclear Information System (INIS)

    Salazar, R.J.; Lane, S.

    1992-02-01

    This Safety Analysis Document (SAD) for the Lawrence Livermore National Laboratory (LLNL) Building 693, Chemical Waste Storage Building (desipated as Building 693 Container Storage Unit in the Laboratory's RCRA Part B permit application), provides the necessary information and analyses to conclude that Building 693 can be operated at low risk without unduly endangering the safety of the building operating personnel or adversely affecting the public or the environment. This Building 693 SAD consists of eight sections and supporting appendices. Section 1 presents a summary of the facility designs and operations and Section 2 summarizes the safety analysis method and results. Section 3 describes the site, the facility desip, operations and management structure. Sections 4 and 5 present the safety analysis and operational safety requirements (OSRs). Section 6 reviews Hazardous Waste Management's (HWM) Quality Assurance (QA) program. Section 7 lists the references and background material used in the preparation of this report Section 8 lists acronyms, abbreviations and symbols. Appendices contain supporting analyses, definitions, and descriptions that are referenced in the body of this report

  18. Canister Storage Building (CSB) safety analysis report, phase 3: Safety analysis documentation supporting CSB construction

    International Nuclear Information System (INIS)

    Garvin, L.J.

    1997-01-01

    The US Department of Energy established the K Basins Spent Nuclear Fuel Project to address safety and environmental concerns associated with deteriorating spent nuclear fuel presently stored under water in the Hanford Site's K Basins, which are located near the Columbia River. Recommendations for a series of aggressive projects to construct and operate systems and facilities to manage the safe removal of K Basins fuel were made in WHC-EP-0830, Hanford Spent Nuclear Fuel Recommended Path Forward, and its subsequent update, WHC-SD-SNF-SP-005, Hanford Spent Nuclear Fuel Project Integrated Process Strategy for K Basins Fuel. The integrated process strategy recommendations include the following steps: Fuel preparation activities at the K Basins, including removing the fuel elements from their K Basin canisters, separating fuel particulate from fuel elements and fuel fragments greater than 0.6 cm (0.25 in.) in any dimension, removing excess sludge from the fuel and fuel fragments by means of flushing, as necessary, and packaging the fuel into multicanister overpacks (MCOs); Removal of free water by draining and vacuum drying at a cold vacuum drying facility ES-122; Dry shipment of fuel from the Cold Vacuum Drying to the Canister Storage Building (CSB), a new facility in the 200 East Area of the Hanford Site

  19. Canister storage building (CSB) safety analysis report phase 3: Safety analysis documentation supporting CSB construction

    Energy Technology Data Exchange (ETDEWEB)

    Garvin, L.J.

    1997-04-28

    The Canister Storage Building (CSB) will be constructed in the 200 East Area of the U.S. Department of Energy (DOE) Hanford Site. The CSB will be used to stage and store spent nuclear fuel (SNF) removed from the Hanford Site K Basins. The objective of this chapter is to describe the characteristics of the site on which the CSB will be located. This description will support the hazard analysis and accident analyses in Chapter 3.0. The purpose of this report is to provide an evaluation of the CSB design criteria, the design's compliance with the applicable criteria, and the basis for authorization to proceed with construction of the CSB.

  20. Systematic documentation and analysis of human genetic variation using the microattribution approach

    Science.gov (United States)

    Giardine, Belinda; Borg, Joseph; Higgs, Douglas R.; Peterson, Kenneth R.; Maglott, Donna; Basak, A. Nazli; Clark, Barnaby; Faustino, Paula; Felice, Alex E.; Francina, Alain; Gallivan, Monica V. E.; Georgitsi, Marianthi; Gibbons, Richard J.; Giordano, Piero C.; Harteveld, Cornelis L.; Joly, Philippe; Kanavakis, Emmanuel; Kollia, Panagoula; Menzel, Stephan; Miller, Webb; Moradkhani, Kamran; Old, John; Papachatzopoulou, Adamantia; Papadakis, Manoussos N.; Papadopoulos, Petros; Pavlovic, Sonja; Philipsen, Sjaak; Radmilovic, Milena; Riemer, Cathy; Schrijver, Iris; Stojiljkovic, Maja; Thein, Swee Lay; Traeger-Synodinos, Jan; Tully, Ray; Wada, Takahito; Waye, John; Wiemann, Claudia; Zukic, Branka; Chui, David H. K.; Wajcman, Henri; Hardison, Ross C.; Patrinos, George P.

    2013-01-01

    We developed a series of interrelated locus-specific databases to store all published and unpublished genetic variation related to these disorders, and then implemented microattribution to encourage submission of unpublished observations of genetic variation to these public repositories 1. A total of 1,941 unique genetic variants in 37 genes, encoding globins (HBA2, HBA1, HBG2, HBG1, HBD, HBB) and other erythroid proteins (ALOX5AP, AQP9, ARG2, ASS1, ATRX, BCL11A, CNTNAP2, CSNK2A1, EPAS1, ERCC2, FLT1, GATA1, GPM6B, HAO2, HBS1L, KDR, KL, KLF1, MAP2K1, MAP3K5, MAP3K7, MYB, NOS1, NOS2, NOS3, NOX3, NUP133, PDE7B, SMAD3, SMAD6, and TOX) are currently documented in these databases with reciprocal attribution of microcitations to data contributors. Our project provides the first example of implementing microattribution to incentivise submission of all known genetic variation in a defined system. It has demonstrably increased the reporting of human variants and now provides a comprehensive online resource for systematically describing human genetic variation in the globin genes and other genes contributing to hemoglobinopathies and thalassemias. The large repository of previously reported data, together with more recent data, acquired by microattribution, demonstrates how the comprehensive documentation of human variation will provide key insights into normal biological processes and how these are perturbed in human genetic disease. Using the microattribution process set out here, datasets which took decades to accumulate for the globin genes could be assembled rapidly for other genes and disease systems. The principles established here for the globin gene system will serve as a model for other systems and the analysis of other common and/or complex human genetic diseases. PMID:21423179

  1. Modern methods of documentation for conservation - digital mapping in metigo® MAP, Software for documentation, mapping and quantity survey and analysis

    Science.gov (United States)

    Siedler, Gunnar; Vetter, Sebastian

    2015-04-01

    Several years of experience of heritage documentation have given a background to develop methods of cartography and digital evaluation. The outcome of which is the development of a 2D-mapping software with integrated image rectification over a period of more then 10 years and that became the state of the art software in Germany initially and now elsewhere for Conservation and Restoration projects. If there are no mapping bases (image plan or CAD-drawing), the user can create its own image plans using different types of rectification functions. Based on true to scale mappings, quantity surveys of areas and lines can be calculated automatically. Digital maps were used for the documentation and analysis of materials and damages, for planning of required action and for calculation of costs. With the help of the hierarchy even large mapping projects with many sub projects can be managed. The results of quantification can be exported to excel spreadsheets for further processing. The combination of image processing and CAD-functionality makes operation of the programm user-friendly, both in the office and on-site. metigo MAP was developed in close cooperation with conservators and restorers. Based on simple equipment consisting of digital camera, laser measuring instrument for measuring distances or total station and standard notebook the mapping software is used in many restoration companies.

  2. Technical documentation in support of the project-specific analysis for construction and operation of the National Ignition Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lazaro, M.A.; Vinikour, W. [Argonne National Lab., IL (United States). Environmental Assessment Div.; Allison, T. [Argonne National Lab., IL (United States). Decision and Information Sciences Div.] [and others

    1996-09-01

    This document provides information that supports or supplements the data and impact analyses presented in the National Ignition Facility (NIF) Project-Specific Analysis (PSA). The purposes of NIF are to achieve fusion ignition in the laboratory for the first time with inertial confinement fusion (ICF) technology and to conduct high- energy-density experiments ins support of national security and civilian application. NIF is an important element in the DOE`s science-based SSM Program, a key mission of which is to ensure the reliability of the nation`s enduring stockpile of nuclear weapons. NIF would also advance the knowledge of basic and applied high-energy- density science and bring the nation a large step closer to developing fusion energy for civilian use. The NIF PSA includes evaluations of the potential environmental impacts of constructing and operating the facility at one of five candidate site and for two design options.

  3. Benchmarking of Document Image Analysis Tasks for Palm Leaf Manuscripts from Southeast Asia

    Directory of Open Access Journals (Sweden)

    Made Windu Antara Kesiman

    2018-02-01

    Full Text Available This paper presents a comprehensive test of the principal tasks in document image analysis (DIA, starting with binarization, text line segmentation, and isolated character/glyph recognition, and continuing on to word recognition and transliteration for a new and challenging collection of palm leaf manuscripts from Southeast Asia. This research presents and is performed on a complete dataset collection of Southeast Asian palm leaf manuscripts. It contains three different scripts: Khmer script from Cambodia, and Balinese script and Sundanese script from Indonesia. The binarization task is evaluated on many methods up to the latest in some binarization competitions. The seam carving method is evaluated for the text line segmentation task, compared to a recently new text line segmentation method for palm leaf manuscripts. For the isolated character/glyph recognition task, the evaluation is reported from the handcrafted feature extraction method, the neural network with unsupervised learning feature, and the Convolutional Neural Network (CNN based method. Finally, the Recurrent Neural Network-Long Short-Term Memory (RNN-LSTM based method is used to analyze the word recognition and transliteration task for the palm leaf manuscripts. The results from all experiments provide the latest findings and a quantitative benchmark for palm leaf manuscripts analysis for researchers in the DIA community.

  4. Analysis Relationship Among Descriptor, References and Citation to Contruct the Inherent Structure of Document Collection

    International Nuclear Information System (INIS)

    Hasibuan, Zainal A.; Mustangimah

    2001-01-01

    There are many characteristics can be used to identify a document which cover characteristics of the documents, cited documents, and citing documents This research explored the inherent structure of a document collection as one of main components of information retrieval system. The characteristics examined are: descriptors, references (cited documents), and citations (citing documents). Three independent variables were studied: co-descriptor, bibliographic coupling, and co-citation. A test collection was constructed by searching on a single descriptor i nformation retrieval i n the CD-ROM version of Education Resource Information Clearinghouse (ERIC), covering the period 1981 through 1985. Descriptors were extracted from ERIC; cited and citing documents associated with the test collection were derived from Social Sciences Citation Index (SSCI), covering the period 1981 through 1990. Three hypothesis were tested in this study, that are: (1) the higher the frequency of co-descriptors between documents, the higher the frequencies of their bibliographic coupling and co-citation; (2) the higher the frequency of bibliographic coupling between documents, the higher the frequencies of their co-citation and co-descriptors; and (3) the higher the frequency of co-citation between documents, the higher the frequencies of their co-descriptors and bibliographic coupling. The results showed that all of three hypothesis are supported statistically and there is a significant linear relationship among the observed variables. It is mean that there is a significant relationship among descriptors, references, and citation, so that it can be used to construct the inherent structure of document collection in order to improve information retrieval system performance

  5. Teaching Integrity in Empirical Research: A Protocol for Documenting Data Management and Analysis

    Science.gov (United States)

    Ball, Richard; Medeiros, Norm

    2012-01-01

    This article describes a protocol the authors developed for teaching undergraduates to document their statistical analyses for empirical research projects so that their results are completely reproducible and verifiable. The protocol is guided by the principle that the documentation prepared to accompany an empirical research project should be…

  6. Language Learning in the Public Eye: An Analysis of Newspapers and Official Documents in England

    Science.gov (United States)

    Graham, Suzanne; Santos, Denise

    2015-01-01

    This article considers the issue of low levels of motivation for foreign language learning in England by exploring how language learning is conceptualised by different key voices in that country through the examination of written data: policy documents and reports on the UK's language needs, curriculum documents and press articles. The extent to…

  7. Documental analysis of Brazilian academic production about evolution teaching (1990-2010: characterization and proposals

    Directory of Open Access Journals (Sweden)

    Caio Samuel Franciscati da Silva

    2013-08-01

    Full Text Available The quantitative and qualitative increasing of researches in Science teaching imposes the periodical mapping need of scientific production about the subject, with a view to identify its own characteristics and tendencies. In this context, researches such as “State of art”, given his executrix character, constitute in modality inquiring that allow us to outline historical scenes for a given area (or subarea of knowledge. In this light, this work aims to outline the panorama of Brazilian academic production, represented by dissertations and thesis, in evolution teaching between 1990- 2010. The documents susceptible of analysis were raised in three online data basis and its selection happened from the reading of titles, abstracts and key-words with views to identify the dissertations and thesis that truly approached the Evolution Teaching. The found results evidence the predominance of dissertations related to the number of thesis and the concentration of academic production in Evolution Teaching in Brazil south-east region, especially in São Paulo state. In researches trends we verified the prevalence of investigations related to the previous conceptions of students and professors (in all teaching levels and to teacher training.

  8. LEARNING STYLES BASED ADAPTIVE INTELLIGENT TUTORING SYSTEMS: DOCUMENT ANALYSIS OF ARTICLES PUBLISHED BETWEEN 2001. AND 2016.

    Directory of Open Access Journals (Sweden)

    Amit Kumar

    2017-12-01

    Full Text Available Actualizing instructional intercessions to suit learner contrasts has gotten extensive consideration. Among these individual contrast factors, the observational confirmation in regards to the academic benefit of learning styles has been addressed, yet the examination on the issue proceeds. Late improvements in web-based executions have driven researchers to re-examine the learning styles in adaptive tutoring frameworks. Adaptivity in intelligent tutoring systems is strongly influenced by the learning style of a learner. This study involved extensive document analysis of adaptive tutoring systems based on learning styles. Seventy-eight studies in literature from 2001 to 2016 were collected and classified under select parameters such as main focus, purpose, research types, methods, types and levels of participants, field/area of application, learner modelling, data gathering tools used and research findings. The current studies reveal that majority of the studies defined a framework or architecture of adaptive intelligent tutoring system (AITS while others focused on impact of AITS on learner satisfaction and academic outcomes. Currents trends, gaps in literature and ications were discussed.

  9. Analysis of Informed Consent Document Utilization in a Minimal-Risk Genetic Study

    Science.gov (United States)

    Desch, Karl; Li, Jun; Kim, Scott; Laventhal, Naomi; Metzger, Kristen; Siemieniak, David; Ginsburg, David

    2012-01-01

    Background The signed informed consent document certifies that the process of informed consent has taken place and provides research participants with comprehensive information about their role in the study. Despite efforts to optimize the informed consent document, only limited data are available about the actual use of consent documents by participants in biomedical research. Objective To examine the use of online consent documents in a minimal-risk genetic study. Design Prospective sibling cohort enrolled as part of a genetic study of hematologic and common human traits. Setting University of Michigan Campus, Ann Arbor, Michigan. Participants Volunteer sample of healthy persons with 1 or more eligible siblings aged 14 to 35 years. Enrollment was through targeted e-mail to student lists. A total of 1209 persons completed the study. Measurements Time taken by participants to review a 2833-word online consent document before indicating consent and identification of a masked hyperlink near the end of the document. Results The minimum predicted reading time was 566 seconds. The median time to consent was 53 seconds. A total of 23% of participants consented within 10 seconds, and 93% of participants consented in less than the minimum predicted reading time. A total of 2.5% of participants identified the masked hyperlink. Limitation The online consent process was not observed directly by study investigators, and some participants may have viewed the consent document more than once. Conclusion Few research participants thoroughly read the consent document before agreeing to participate in this genetic study. These data suggest that current informed consent documents, particularly for low-risk studies, may no longer serve the intended purpose of protecting human participants, and the role of these documents should be reassessed. Primary Funding Source National Institutes of Health. PMID:21893624

  10. Analysis of informed consent document utilization in a minimal-risk genetic study.

    Science.gov (United States)

    Desch, Karl; Li, Jun; Kim, Scott; Laventhal, Naomi; Metzger, Kristen; Siemieniak, David; Ginsburg, David

    2011-09-06

    The signed informed consent document certifies that the process of informed consent has taken place and provides research participants with comprehensive information about their role in the study. Despite efforts to optimize the informed consent document, only limited data are available about the actual use of consent documents by participants in biomedical research. To examine the use of online consent documents in a minimal-risk genetic study. Prospective sibling cohort enrolled as part of a genetic study of hematologic and common human traits. University of Michigan Campus, Ann Arbor, Michigan. Volunteer sample of healthy persons with 1 or more eligible siblings aged 14 to 35 years. Enrollment was through targeted e-mail to student lists. A total of 1209 persons completed the study. Time taken by participants to review a 2833-word online consent document before indicating consent and identification of a masked hyperlink near the end of the document. The minimum predicted reading time was 566 seconds. The median time to consent was 53 seconds. A total of 23% of participants consented within 10 seconds, and 93% of participants consented in less than the minimum predicted reading time. A total of 2.5% of participants identified the masked hyperlink. The online consent process was not observed directly by study investigators, and some participants may have viewed the consent document more than once. Few research participants thoroughly read the consent document before agreeing to participate in this genetic study. These data suggest that current informed consent documents, particularly for low-risk studies, may no longer serve the intended purpose of protecting human participants, and the role of these documents should be reassessed. National Institutes of Health.

  11. The use of fingerprints available on the web in false identity documents: Analysis from a forensic intelligence perspective.

    Science.gov (United States)

    Girelli, Carlos Magno Alves

    2016-05-01

    Fingerprints present in false identity documents were found on the web. In some cases, laterally reversed (mirrored) images of a same fingerprint were observed in different documents. In the present work, 100 fingerprints images downloaded from the web, as well as their reversals obtained by image editing, were compared between themselves and against the database of the Brazilian Federal Police AFIS, in order to better understand trends about this kind of forgery in Brazil. Some image editing effects were observed in the analyzed fingerprints: addition of artifacts (such as watermarks), image rotation, image stylization, lateral reversal and tonal reversal. Discussion about lateral reversals' detection is presented in this article, as well as suggestion to reduce errors due to missed HIT decisions between reversed fingerprints. The present work aims to highlight the importance of the fingerprints' analysis when performing document examination, especially when only copies of documents are available, something very common in Brazil. Besides the intrinsic features of the fingermarks considered in three levels of details by ACE-V methodology, some visual features of the fingerprints images can be helpful to identify sources of forgeries and modus operandi, such as: limits and image contours, fails in the friction ridges caused by excess or lack of inking and presence of watermarks and artifacts arising from the background. Based on the agreement of such features in fingerprints present in different identity documents and also on the analysis of the time and location where the documents were seized, it is possible to highlight potential links between apparently unconnected crimes. Therefore, fingerprints have potential to reduce linkage blindness and the present work suggests the analysis of fingerprints when profiling false identity documents, as well as the inclusion of fingerprints features in the profile of the documents. Copyright © 2016 Elsevier Ireland Ltd. All

  12. Predicting Automotive Interior Noise Including Wind Noise by Statistical Energy Analysis

    OpenAIRE

    Yoshio Kurosawa

    2017-01-01

    The applications of soundproof materials for reduction of high frequency automobile interior noise have been researched. This paper presents a sound pressure prediction technique including wind noise by Hybrid Statistical Energy Analysis (HSEA) in order to reduce weight of acoustic insulations. HSEA uses both analytical SEA and experimental SEA. As a result of chassis dynamo test and road test, the validity of SEA modeling was shown, and utility of the method was confirmed.

  13. Promoting Entrepreneurship in Higher Education: Analysis of European Union Documents and Lithuanian Case Study

    Directory of Open Access Journals (Sweden)

    Viktorija Stokaitė

    2013-01-01

    Full Text Available The Chairman of the European Commission J.M Barroso, as the main “Europe 2020” strategic target for the upcoming ten years, indicates the creation of an innovative, stable and integrated economy. Higher education and business communication promotion and synergy are being dedicated as a prior target for all EU and EU member countries to be able to continue increasing employment, productivity, as well as social connections. The research of the enterprise and its stimulation in higher education (using higher education and business collaboration is not deep enough, although the enterprise’s multiple phenomenon were analysed from many perspectives. It is being planned to raise EU’s investments to youth much more compared to other main parts of the budget in 2014-2020. Analysis of European Union documents and Lithuanian case studies was chosen on purpose according to the enterprise’s created added value for European development. Realization, creativity, initiative, motivation, taking risks, planning and reaching personal goals are the main parts of the enterprise. Development of these skills in higher education is becoming very important because of “the advantage of the competitiveness is being determined by country‘s social education therefore the effective usage of human recourses is the most important part seeking to increase stabile economical and social well being.” Research of the EU’s and Lithuania’s national documentation and scientific literature review of entrepreneurship in higher education identifies the current enterprise position in education. According to the analyses of the documentation and the scientific literature review, the enterprise’s evaluation level was appointed. The new beginning of the enterprise in higher education is being started after the research was done and centrepiece’s promotion was critically evaluated in the EU and Lithuania. In October, 2011 the committee of the EU created a new work

  14. Three Years of Unmediated Document Delivery: An Analysis and Consideration of Collection Development Priorities.

    Science.gov (United States)

    Chan, Emily K; Mune, Christina; Wang, YiPing; Kendall, Susan L

    2016-01-01

    Like most academic libraries, San José State University Library is struggling to meet users' rising expectations for immediate information within the financial confines of a flat budget. To address acquisition of nonsubscribed article content, particularly outside of business hours, San José State University Library implemented Copyright Clearance Center's Get It Now, a document delivery service. Three academic years of analyzed data, which involves more than 10,000 requests, and the subsequent collection development actions taken by the library will be discussed. The value and challenges of patron-driven, unmediated document delivery services in conjunction with traditional document delivery services will be considered.

  15. Evaluation of Nursing Documentation Completion of Stroke Patients in the Emergency Department: A Pre-Post Analysis Using Flowsheet Templates and Clinical Decision Support.

    Science.gov (United States)

    Richardson, Karen J; Sengstack, Patricia; Doucette, Jeffrey N; Hammond, William E; Schertz, Matthew; Thompson, Julie; Johnson, Constance

    2016-02-01

    The primary aim of this performance improvement project was to determine whether the electronic health record implementation of stroke-specific nursing documentation flowsheet templates and clinical decision support alerts improved the nursing documentation of eligible stroke patients in seven stroke-certified emergency departments. Two system enhancements were introduced into the electronic record in an effort to improve nursing documentation: disease-specific documentation flowsheets and clinical decision support alerts. Using a pre-post design, project measures included six stroke management goals as defined by the National Institute of Neurological Disorders and Stroke and three clinical decision support measures based on entry of orders used to trigger documentation reminders for nursing: (1) the National Institutes of Health's Stroke Scale, (2) neurological checks, and (3) dysphagia screening. Data were reviewed 6 months prior (n = 2293) and 6 months following the intervention (n = 2588). Fisher exact test was used for statistical analysis. Statistical significance was found for documentation of five of the six stroke management goals, although effect sizes were small. Customizing flowsheets to meet the needs of nursing workflow showed improvement in the completion of documentation. The effects of the decision support alerts on the completeness of nursing documentation were not statistically significant (likely due to lack of order entry). For example, an order for the National Institutes of Health Stroke Scale was entered only 10.7% of the time, which meant no alert would fire for nursing in the postintervention group. Future work should focus on decision support alerts that trigger reminders for clinicians to place relevant orders for this population.

  16. A structural design and analysis of a piping system including seismic load

    International Nuclear Information System (INIS)

    Hsieh, B.J.; Kot, C.A.

    1991-01-01

    The structural design/analysis of a piping system at a nuclear fuel facility is used to investigate some aspects of current design procedures. Specifically the effect of using various stress measures including ASME Boiler ampersand Pressure Vessel (B ampersand PV) Code formulas is evaluated. It is found that large differences in local maximum stress values may be calculated depending on the stress criterion used. However, when the global stress maximum for the entire system are compared the differences are much smaller, being nevertheless, for some load combinations, of the order of 50 percent. The effect of using an Equivalent Static Method (ESM) analysis is also evaluated by comparing its results with those obtained from a Response Spectrum Method (RSM) analysis with the modal responses combined by using the absolute summation (ABS), by using the square root of the squares (SRSS), and by using the 10 percent method (10PC). It is shown that for a spectrum amplification factor (equivalent static coefficient greater than unity) of at least 1.32 must be used in the current application of the ESM analysis in order to obtain results which are conservative in all aspects relative to an RSM analysis based on ABS. However, it appears that an adequate design would be obtained from the ESM approach even without the use of a spectrum amplification factor. 7 refs., 3 figs., 3 tabs

  17. Seismic analysis of the Nuclear Fuel Service Reprocessing Plant at West Valley, New York: documentation

    International Nuclear Information System (INIS)

    Murray, R.C.; Nelson, T.A.; Davito, A.M.

    1977-01-01

    This material was generated as part of a seismic case review of the NFS Reprocessing Plant. This study is documented in UCRL-52266. The material is divided into two parts: mathematical model information, and ultimate load calculations and comparisons

  18. What makes papers visible on social media? An analysis of various document characteristics

    OpenAIRE

    Zahedi, Zohreh; Costas, Rodrigo; Larivière, Vincent; Haustein, Stefanie

    2017-01-01

    In this study we have investigated the relationship between different document characteristics and the number of Mendeley readership counts, tweets, Facebook posts, mentions in blogs and mainstream media for 1.3 million papers published in journals covered by the Web of Science (WoS). It aims to demonstrate that how factors affecting various social media-based indicators differ from those influencing citations and which document types are more popular across different platforms. Our results h...

  19. Corporate ethical codes as strategic documents: An analysis of success and failure

    OpenAIRE

    Stevens, Betsy

    2009-01-01

    Ethical codes state the major philosophical principles and values in organizations and function as policy documents which define the responsibilities of organizations to stakeholders. They spell out the conduct expected of employees and articulate the acceptable ethical parameters of behavior in the organization. Most large US and multinational firms today have a code. If utilized effectively and embraced, codes can be key strategic documents in organizations for moderating emp...

  20. Documented Safety Analysis Addendum for the Neutron Radiography Reactor Facility Core Conversion

    Energy Technology Data Exchange (ETDEWEB)

    Boyd D. Christensen

    2009-05-01

    The Neutron Radiography Reactor Facility (NRAD) is a Training, Research, Isotope Production, General Atomics (TRIGA) reactor which was installed in the Idaho National Laboratory (INL) Hot Fuels Examination Facility (HFEF) at the Materials and Fuels Complex (MFC) in the mid 1970s. The facility provides researchers the capability to examine both irradiated and non-irradiated materials in support of reactor fuel and components programs through non-destructive neutron radiography examination. The facility has been used in the past as one facet of a suite of reactor fuels and component examination facilities available to researchers at the INL and throughout the DOE complex. The facility has also served various commercial research activities in addition to the DOE research and development support. The reactor was initially constructed using Fuel Lifetime Improvement Program (FLIP)- type highly enriched uranium (HEU) fuel obtained from the dismantled Puerto Rico Nuclear Center (PRNC) reactor. In accordance with international non-proliferation agreements, the NRAD core will be converted to a low enriched uranium (LEU) fuel and will continue to utilize the PRNC control rods, control rod drives, startup source, and instrument console as was previously used with the HEU core. The existing NRAD Safety Analysis Report (SAR) was created and maintained in the preferred format of the day, combining sections of both DOE-STD-3009 and Nuclear Regulatory Commission Regulatory Guide 1.70. An addendum was developed to cover the refueling and reactor operation with the LEU core. This addendum follows the existing SAR format combining required formats from both the DOE and NRC. This paper discusses the project to successfully write a compliant and approved addendum to the existing safety basis documents.

  1. Clinical decision support improves quality of telephone triage documentation - an analysis of triage documentation before and after computerized clinical decision support

    Science.gov (United States)

    2014-01-01

    Background Clinical decision support (CDS) has been shown to be effective in improving medical safety and quality but there is little information on how telephone triage benefits from CDS. The aim of our study was to compare triage documentation quality associated with the use of a clinical decision support tool, ExpertRN©. Methods We examined 50 triage documents before and after a CDS tool was used in nursing triage. To control for the effects of CDS training we had an additional control group of triage documents created by nurses who were trained in the CDS tool, but who did not use it in selected notes. The CDS intervention cohort of triage notes was compared to both the pre-CDS notes and the CDS trained (but not using CDS) cohort. Cohorts were compared using the documentation standards of the American Academy of Ambulatory Care Nursing (AAACN). We also compared triage note content (documentation of associated positive and negative features relating to the symptoms, self-care instructions, and warning signs to watch for), and documentation defects pertinent to triage safety. Results Three of five AAACN documentation standards were significantly improved with CDS. There was a mean of 36.7 symptom features documented in triage notes for the CDS group but only 10.7 symptom features in the pre-CDS cohort (p triage note documentation quality. CDS-aided triage notes had significantly more information about symptoms, warning signs and self-care. The changes in triage documentation appeared to be the result of the CDS alone and not due to any CDS training that came with the CDS intervention. Although this study shows that CDS can improve documentation, further study is needed to determine if it results in improved care. PMID:24645674

  2. Reimbursement for injury-induced medical expenses in Chinese social medical insurance schemes: A systematic analysis of legislative documents.

    Science.gov (United States)

    Gao, Yuyan; Li, Li; Schwebel, David C; Ning, Peishan; Cheng, Peixia; Hu, Guoqing

    2018-01-01

    Social medical insurance schemes are crucial for realizing universal health coverage and health equity. The aim of this study was to investigate whether and how reimbursement for injury-induced medical expenses is addressed in Chinese legislative documents relevant to social medical insurance. We retrieved legislative documents from the China National Knowledge Infrastructure and the Lawyee databases. Four types of social medical insurance schemes were included: urban employee basic medical insurance, urban resident basic medical insurance, new rural cooperative medical system, and urban and rural resident medical insurance. Text analyses were conducted on all identified legislative documents. As a result, one national law and 1,037 local legislative documents were identified. 1,012 of the 1,038 documents provided for reimbursement. Of the 1,012 documents, 828 (82%) provided reimbursement only for injuries without a legally responsible person/party or not caused by self-harm, alcohol use, drug use, or other law violations, and 162 (16%) did not include any details concerning implementation. Furthermore, 760 (92%) of the 828 did not provide an exception clause applying to injuries when a responsible person/party could not be contacted or for situations when the injured person cannot obtain reimbursement from the responsible person/party. Thus, most Chinese legislative documents related to social medical insurance do not provide reimbursement for medical expenses from injuries having a legally responsible person/party or those caused by illegal behaviors. We argue that all injury-induced medical expenses should be covered by legislative documents related to social medical insurance in China, no matter what the cause of the injury. Further research is needed to explore the acceptability and feasibility of such policy changes.

  3. Isogeometric analysis of free-form Timoshenko curved beams including the nonlinear effects of large deformations

    Science.gov (United States)

    Hosseini, Seyed Farhad; Hashemian, Ali; Moetakef-Imani, Behnam; Hadidimoud, Saied

    2018-03-01

    In the present paper, the isogeometric analysis (IGA) of free-form planar curved beams is formulated based on the nonlinear Timoshenko beam theory to investigate the large deformation of beams with variable curvature. Based on the isoparametric concept, the shape functions of the field variables (displacement and rotation) in a finite element analysis are considered to be the same as the non-uniform rational basis spline (NURBS) basis functions defining the geometry. The validity of the presented formulation is tested in five case studies covering a wide range of engineering curved structures including from straight and constant curvature to variable curvature beams. The nonlinear deformation results obtained by the presented method are compared to well-established benchmark examples and also compared to the results of linear and nonlinear finite element analyses. As the nonlinear load-deflection behavior of Timoshenko beams is the main topic of this article, the results strongly show the applicability of the IGA method to the large deformation analysis of free-form curved beams. Finally, it is interesting to notice that, until very recently, the large deformations analysis of free-form Timoshenko curved beams has not been considered in IGA by researchers.

  4. A tool to include gamma analysis software into a quality assurance program.

    Science.gov (United States)

    Agnew, Christina E; McGarry, Conor K

    2016-03-01

    To provide a tool to enable gamma analysis software algorithms to be included in a quality assurance (QA) program. Four image sets were created comprising two geometric images to independently test the distance to agreement (DTA) and dose difference (DD) elements of the gamma algorithm, a clinical step and shoot IMRT field and a clinical VMAT arc. The images were analysed using global and local gamma analysis with 2 in-house and 8 commercially available software encompassing 15 software versions. The effect of image resolution on gamma pass rates was also investigated. All but one software accurately calculated the gamma passing rate for the geometric images. Variation in global gamma passing rates of 1% at 3%/3mm and over 2% at 1%/1mm was measured between software and software versions with analysis of appropriately sampled images. This study provides a suite of test images and the gamma pass rates achieved for a selection of commercially available software. This image suite will enable validation of gamma analysis software within a QA program and provide a frame of reference by which to compare results reported in the literature from various manufacturers and software versions. Copyright © 2015. Published by Elsevier Ireland Ltd.

  5. Analysis of general and specific combining abilities of popcorn populations, including selfed parents

    Directory of Open Access Journals (Sweden)

    José Marcelo Soriano Viana

    2003-12-01

    Full Text Available Estimation of general and specific combining ability effects in a diallel analysis of cross-pollinating populations, including the selfed parents, is presented in this work. The restrictions considered satisfy the parametric values of the GCA and SCA effects. The method is extended to self-pollinating populations (suitable for other species, without the selfed parents. The analysis of changes in population means due to inbreeding (sensitivity to inbreeding also permits to assess the predominant direction of dominance deviations and the relative genetic variability in each parent population. The methodology was used to select popcorn populations for intra- and inter-population breeding programs and for hybrid production, developed at the Federal University of Viçosa, MG, Brazil. Two yellow pearl grain popcorn populations were selected.

  6. Slideline verification for multilayer pressure vessel and piping analysis including tangential motion

    International Nuclear Information System (INIS)

    Van Gulick, L.A.

    1984-01-01

    Nonlinear finite element method (FEM) computer codes with slideline algorithm implementations should be useful for the analysis of prestressed multilayer pressure vessels and piping. This paper presents closed form solutions including the effects of tangential motion useful for verifying slideline implementations for this purpose. The solutions describe stresses and displacements of a long internally pressurized elastic-plastic cylinder initially separated from an elastic outer cylinder by a uniform gap. Comparison of closed form and FEM results evaluates the usefulness of the closed form solution and the validity of the sideline implementation used

  7. Analysis Technique for Exhaust Gas Including PFCs from Microelectronics Manufacturing Processes

    Science.gov (United States)

    Tomita, Nobuyasu; Isaki, Ryuichiro

    In the manufacturing processes of Semiconductor and the Liquid Crystal Display (LCD), Perfluorocompounds (PFCs), Sulfurhexafluoride (SF6) and Nitrogenfluoride (NF3), which have high Green house effect,are used in large quantities. As emission reduction of these gases, the following countermeasures are taken. 1. Opimization of PFCs usage 2. Utilization of alternative gas 3. Instllation of Scrubber for exhaust gas treatment To inspect the effect of countermeasure that are introduced for these PFCs emission reduction, it is necessary to analyze PFCs in exhaust gas. In this report, we will discribe about analysis technique for exhaust gas including PFCs from microelectornics manufacturing processes.

  8. Multi trace element analysis of dry biological materials by neutron activation analysis including a chemical group separation

    International Nuclear Information System (INIS)

    Weers, C.A.

    1980-07-01

    Multi-element analysis of dry biological material by neutron activation analysis has to include radiochemical separation. The evaporation process is described in terms of the half-volume. The pretreatment of the samples and the development of the destruction-evaporation apparatus are described. The successive adsorption steps with active charcoal, Al 2 O 3 and coprecipitation with Fe(OH) 3 are described. Results obtained for standard reference materials are summarized. (G.T.H.)

  9. Analysis of initial events in radiation-induced lymphomagenesis. Investigation of chromosome aberration including translocations

    International Nuclear Information System (INIS)

    Chen Ying

    1995-01-01

    To investigate the contribution of chromosome aberrations in radiation-induced lymphomagenesis, chromosome G-banding analysis of the lymphoma cells (8 groups and 34 kinds of cells), of which each group was derived from a single donor by intra-thymic injection of a limited number of prelymphoma cells, was performed. Many numerical and structural aberrations were observed in the donor-derived T cell lymphomas. Common aberrations including translocations were found almost in the lymphomas of all groups. Translocations between chromosomes 11 and 12, 12 and 15, 7 and 10, 1 and 13, 6 and X were found in D, E, F, G, H, groups, respectively. There were also common aberrations such as trisomy 15 in A and F groups. These results indicate that chromosome aberrations including translocations may be important candidates of initiating events in radiation-induced lymphomagenesis

  10. Page Layout Analysis of the Document Image Based on the Region Classification in a Decision Hierarchical Structure

    Directory of Open Access Journals (Sweden)

    Hossein Pourghassem

    2010-10-01

    Full Text Available The conversion of document image to its electronic version is a very important problem in the saving, searching and retrieval application in the official automation system. For this purpose, analysis of the document image is necessary. In this paper, a hierarchical classification structure based on a two-stage segmentation algorithm is proposed. In this structure, image is segmented using the proposed two-stage segmentation algorithm. Then, the type of the image regions such as document and non-document image is determined using multiple classifiers in the hierarchical classification structure. The proposed segmentation algorithm uses two algorithms based on wavelet transform and thresholding. Texture features such as correlation, homogeneity and entropy that extracted from co-occurrenc matrix and also two new features based on wavelet transform are used to classifiy and lable the regions of the image. The hierarchical classifier is consisted of two Multilayer Perceptron (MLP classifiers and a Support Vector Machine (SVM classifier. The proposed algorithm is evaluated on a database consisting of document and non-document images that provides from Internet. The experimental results show the efficiency of the proposed approach in the region segmentation and classification. The proposed algorithm provides accuracy rate of 97.5% on classification of the regions.

  11. Documentation for a Structural Optimization Procedure Developed Using the Engineering Analysis Language (EAL)

    Science.gov (United States)

    Martin, Carl J., Jr.

    1996-01-01

    This report describes a structural optimization procedure developed for use with the Engineering Analysis Language (EAL) finite element analysis system. The procedure is written primarily in the EAL command language. Three external processors which are written in FORTRAN generate equivalent stiffnesses and evaluate stress and local buckling constraints for the sections. Several built-up structural sections were coded into the design procedures. These structural sections were selected for use in aircraft design, but are suitable for other applications. Sensitivity calculations use the semi-analytic method, and an extensive effort has been made to increase the execution speed and reduce the storage requirements. There is also an approximate sensitivity update method included which can significantly reduce computational time. The optimization is performed by an implementation of the MINOS V5.4 linear programming routine in a sequential liner programming procedure.

  12. Analysis of physiotherapy documentation of patients′ records and discharge plans in a tertiary hospital

    Directory of Open Access Journals (Sweden)

    Olajide A Olawale

    2015-01-01

    Full Text Available Background and Objective: Accurate documentation promotes continuity of care and facilitates dissemination of information concerning the patient to all members of the health care team. This study was designed to analyze the pattern of physiotherapy documentation of the patients' records and discharge plans in a tertiary hospital in Lagos, Nigeria. Materials and Methods: A total of 503 case files from the four units of the Physiotherapy Department of the hospital were examined for accuracy of records. The D-Catch instrument was used to quantify the accuracy of record structure, admission data, physiotherapy examination, physiotherapy diagnosis, patients' prognoses based on the plan of care, physiotherapy intervention, progress and outcome evaluation, legibility, and discharge/discontinuation plan. Results: “Accuracy of legibility” domain had the highest accuracy score: 401 (79.72% case files had an accuracy score of 4. The domain “accuracy of the discharge/discontinuation summary” had the lowest accuracy score: 502 (99.80% case files had an accuracy score of 1. Conclusion: Documentation of the plan of care made in the hospital for the period of this study did not fully conform to the guidelines of the World Confederation for Physical Therapy (WCPT. The accuracy of physiotherapy documentation needs to be improved in order to promote optimal continuity of care, improve efficiency and quality of care, and recognize patients' needs. Implementation and use of electronically produced documentation might help physiotherapists to organize their notes more accurately.

  13. Steady-state analysis of activated sludge processes with a settler model including sludge compression.

    Science.gov (United States)

    Diehl, S; Zambrano, J; Carlsson, B

    2016-01-01

    A reduced model of a completely stirred-tank bioreactor coupled to a settling tank with recycle is analyzed in its steady states. In the reactor, the concentrations of one dominant particulate biomass and one soluble substrate component are modelled. While the biomass decay rate is assumed to be constant, growth kinetics can depend on both substrate and biomass concentrations, and optionally model substrate inhibition. Compressive and hindered settling phenomena are included using the Bürger-Diehl settler model, which consists of a partial differential equation. Steady-state solutions of this partial differential equation are obtained from an ordinary differential equation, making steady-state analysis of the entire plant difficult. A key result showing that the ordinary differential equation can be replaced with an approximate algebraic equation simplifies model analysis. This algebraic equation takes the location of the sludge-blanket during normal operation into account, allowing for the limiting flux capacity caused by compressive settling to easily be included in the steady-state mass balance equations for the entire plant system. This novel approach grants the possibility of more realistic solutions than other previously published reduced models, comprised of yet simpler settler assumptions. The steady-state concentrations, solids residence time, and the wastage flow ratio are functions of the recycle ratio. Solutions are shown for various growth kinetics; with different values of biomass decay rate, influent volumetric flow, and substrate concentration. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Attenuated total reflectance Fourier transform infrared spectroscopy analysis of red seal inks on questioned document.

    Science.gov (United States)

    Nam, Yun Sik; Park, Jin Sook; Kim, Nak-Kyoon; Lee, Yeonhee; Lee, Kang-Bong

    2014-07-01

    Seals are traditionally used in the Far East Asia to stamp an impression on a document in place of a signature. In this study, an accuser claimed that a personal contract regarding mining development rights acquired by a defendant was devolved to the accuser because the defendant stamped the devolvement contract in the presence of the accuser and a witness. The accuser further stated that the seal ink stamped on the devolvement contract was the same as that stamped on the development rights application document. To verify this, the seals used in two documents were analyzed using micro-attenuated total reflectance Fourier transform infrared spectroscopy and infrared spectra. The findings revealed that the seals originated from different manufacturers. Thus, the accuser's claim on the existence of a devolvement contract was proved to be false. © 2014 American Academy of Forensic Sciences.

  15. Market Analysis and Consumer Impacts Source Document. Part I. The Motor Vehicle Market in the Late 1970's

    Science.gov (United States)

    1980-12-01

    The source document on motor vehicle market analysis and consumer impact consists of three parts. Part I is an integrated overview of the motor vehicle market in the late 1970's, with sections on the structure of the market, motor vehicle trends, con...

  16. "I Like to Plan Events": A Document Analysis of Essays Written by Applicants to a Public Relations Program

    Science.gov (United States)

    Taylor, Ronald E.

    2016-01-01

    A document analysis of 249 essays written during a 5-year period by applicants to a public relations program at a major state university in the southeast suggests that there are enduring reasons why students choose to major in public relations. Public relations is described as a major that allows for and encourages creative expression and that…

  17. Ethics, Power, Internationalisation and the Postcolonial: A Foucauldian Discourse Analysis of Policy Documents in Two Scottish Universities

    Science.gov (United States)

    Guion Akdag, Emma; Swanson, Dalene M.

    2018-01-01

    This paper provides a critical discussion of internationalisation in Higher Education (HE), and exemplifies a process of uncovering the investments in power and ideology through the partial analysis of four strategic internationalisation documents at two Scottish Higher Education institutions, as part of an ongoing international study into the…

  18. Fernando Pessoa and Aleister Crowley: new discoveries and a new analysis of the documents in the Gerald Yorke Collection

    NARCIS (Netherlands)

    Pasi, M.; Ferrari, P.

    2012-01-01

    The documents concerning the relationship between Fernando Pessoa and Aleister Crowley preserved in the Yorke Collection at the Warburg Institute (London) have been known for some time. However, recent new findings have prompted a new analysis of the dossier. The purpose of this article is to have a

  19. What makes papers visible on social media? An analysis of various document characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Zahedi, Z.; Costas, R.; Lariviere, V.; Haustein, S.

    2016-07-01

    In this study we have investigated the relationship between different document characteristics and the number of Mendeley readership counts, tweets, Facebook posts, mentions in blogs and mainstream media for 1.3 million papers published in journals covered by the Web of Science (WoS). It aims to demonstrate that how factors affecting various social media-based indicators differ from those influencing citations and which document types are more popular across different platforms. Our results highlight the heterogeneous nature of altmetrics, which encompasses different types of uses and user groups engaging with research on social media. (Author)

  20. A multimethod analysis of shared decision-making in hospice interdisciplinary team meetings including family caregivers.

    Science.gov (United States)

    Washington, Karla T; Oliver, Debra Parker; Gage, L Ashley; Albright, David L; Demiris, George

    2016-03-01

    Much of the existing research on shared decision-making in hospice and palliative care focuses on the provider-patient dyad; little is known about shared decision-making that is inclusive of family members of patients with advanced disease. We sought to describe shared decision-making as it occurred in hospice interdisciplinary team meetings that included family caregivers as participants using video-conferencing technology. We conducted a multimethod study in which we used content and thematic analysis techniques to analyze video-recordings of hospice interdisciplinary team meetings (n = 100), individual interviews of family caregivers (n = 73) and hospice staff members (n = 78), and research field notes. Participants in the original studies from which data for this analysis were drawn were hospice family caregivers and staff members employed by one of five different community-based hospice agencies located in the Midwestern United States. Shared decision-making occurred infrequently in hospice interdisciplinary team meetings that included family caregivers. Barriers to shared decision-making included time constraints, communication skill deficits, unaddressed emotional needs, staff absences, and unclear role expectations. The hospice philosophy of care, current trends in healthcare delivery, the interdisciplinary nature of hospice teams, and the designation of a team leader/facilitator supported shared decision-making. The involvement of family caregivers in hospice interdisciplinary team meetings using video-conferencing technology creates a useful platform for shared decision-making; however, steps must be taken to transform family caregivers from meeting attendees to shared decision-makers. © The Author(s) 2015.

  1. Diversity of Pseudomonas Genomes, Including Populus-Associated Isolates, as Revealed by Comparative Genome Analysis.

    Science.gov (United States)

    Jun, Se-Ran; Wassenaar, Trudy M; Nookaew, Intawat; Hauser, Loren; Wanchai, Visanu; Land, Miriam; Timm, Collin M; Lu, Tse-Yuan S; Schadt, Christopher W; Doktycz, Mitchel J; Pelletier, Dale A; Ussery, David W

    2016-01-01

    The Pseudomonas genus contains a metabolically versatile group of organisms that are known to occupy numerous ecological niches, including the rhizosphere and endosphere of many plants. Their diversity influences the phylogenetic diversity and heterogeneity of these communities. On the basis of average amino acid identity, comparative genome analysis of >1,000 Pseudomonas genomes, including 21 Pseudomonas strains isolated from the roots of native Populus deltoides (eastern cottonwood) trees resulted in consistent and robust genomic clusters with phylogenetic homogeneity. All Pseudomonas aeruginosa genomes clustered together, and these were clearly distinct from other Pseudomonas species groups on the basis of pangenome and core genome analyses. In contrast, the genomes of Pseudomonas fluorescens were organized into 20 distinct genomic clusters, representing enormous diversity and heterogeneity. Most of our 21 Populus-associated isolates formed three distinct subgroups within the major P. fluorescens group, supported by pathway profile analysis, while two isolates were more closely related to Pseudomonas chlororaphis and Pseudomonas putida. Genes specific to Populus-associated subgroups were identified. Genes specific to subgroup 1 include several sensory systems that act in two-component signal transduction, a TonB-dependent receptor, and a phosphorelay sensor. Genes specific to subgroup 2 contain hypothetical genes, and genes specific to subgroup 3 were annotated with hydrolase activity. This study justifies the need to sequence multiple isolates, especially from P. fluorescens, which displays the most genetic variation, in order to study functional capabilities from a pangenomic perspective. This information will prove useful when choosing Pseudomonas strains for use to promote growth and increase disease resistance in plants. Copyright © 2015 Jun et al.

  2. Analysis of Nature of Science Included in Recent Popular Writing Using Text Mining Techniques

    Science.gov (United States)

    Jiang, Feng; McComas, William F.

    2014-01-01

    This study examined the inclusion of nature of science (NOS) in popular science writing to determine whether it could serve supplementary resource for teaching NOS and to evaluate the accuracy of text mining and classification as a viable research tool in science education research. Four groups of documents published from 2001 to 2010 were…

  3. Documenting the biodiversity of the Madrean Archipelago: An analysis of a virtual flora and fauna

    Science.gov (United States)

    Nicholas S. Deyo; Thomas R. Van Devender; Alex Smith; Edward. Gilbert

    2013-01-01

    The Madrean Archipelago Biodiversity Assessment (MABA) of Sky Island Alliance is an ambitious project to document the distributions of all species of animals and plants in the Madrean Archipelago, focusing particularly on northeastern Sonora and northwestern Chihuahua, Mexico. The information is made available through MABA’s online database (madrean.org). The sources...

  4. Internationalization Impact on PhD Training Policy in Russia: Insights from the Comparative Document Analysis

    Science.gov (United States)

    Chigisheva, Oksana; Soltovets, Elena; Bondarenko, Anna

    2017-01-01

    The relevance of the study is due to the need for an objective picture of the Russian third level tertiary education transformation driven by internationalization issues and global trends in education. The article provides an analytical comparative review of the official documents related to the main phases of education reform in Russia and…

  5. ANALYSIS OF TERRESTRIAL LASER SCANNING AND PHOTOGRAMMETRY DATA FOR DOCUMENTATION OF HISTORICAL ARTIFACTS

    Directory of Open Access Journals (Sweden)

    R. A. Kuçak

    2016-10-01

    Full Text Available Historical artifacts living from the past until today exposed to many destructions non-naturally or naturally. For this reason, The protection and documentation studies of Cultural Heritage to inform the next generations are accelerating day by day in the whole world. The preservation of historical artifacts using advanced 3D measurement technologies becomes an efficient tool for mapping solutions. There are many methods for documentation and restoration of historic structures. In addition to traditional methods such as simple hand measurement and tachometry, terrestrial laser scanning is rapidly becoming one of the most commonly used techniques due to its completeness, accuracy and fastness characteristics. This study evaluates terrestrial laser scanning(TLS technology and photogrammetry for documenting the historical artifacts facade data in 3D Environment. PhotoModeler software developed by Eos System was preferred for Photogrammetric method. Leica HDS 6000 laser scanner developed by Leica Geosystems and Cyclone software which is the laser data evaluation software belonging to the company is preferred for Terrestrial Laser Scanning method. Taking into account the results obtained with this software product is intended to provide a contribution to the studies for the documentation of cultural heritage.

  6. Enterprise Document Management

    Data.gov (United States)

    US Agency for International Development — The function of the operation is to provide e-Signature and document management support for Acquisition and Assisitance (A&A) documents including vouchers in...

  7. Intranet Document Management Systems.

    Science.gov (United States)

    Wen, H. Joseph; Yen, David C.; Lin, Binshan

    1998-01-01

    Explains how intranets facilitate documentation availability within a company at substantial cost savings. Topics include intranet document management systems (IDMS); publication costs for printed materials; hardware and software specifications; performance; and security. (Author/LRW)

  8. Housing First and harm reduction: a rapid review and document analysis of the US and Canadian open-access literature.

    Science.gov (United States)

    Watson, Dennis P; Shuman, Valery; Kowalsky, James; Golembiewski, Elizabeth; Brown, Molly

    2017-05-23

    Housing First is an evidence-based practice intended to serve chronically homeless individuals with co-occurring serious mental illness and substance use disorders. Despite housing active substance users, harm reduction is an often-overlooked element during the Housing First implementation process in real-world settings. In this paper, we explore the representation of the Housing First model within the open-access scholarly literature as a potential contributing factor for this oversight. We conducted a rapid review of the US and Canadian open-access Housing First literature. We followed a document analysis approach, to form an interpretation of the articles' content related to our primary research questions. A total of 55 articles on Housing First were included in the final analysis. Only 21 of these articles (38.1%) included explicit mention of harm reduction. Of the 34 articles that did not discuss harm reduction, 22 provided a description of the Housing First model indicating it does not require abstinence from substance use; however, descriptions did not all clearly indicate abstinence was not required beyond program entry. Additional Housing First descriptions focused on the low-barrier entry criteria and/or the intervention's client-centeredness. Our review demonstrated a lack of both explicit mention and informed discussion of harm reduction in the Housing First literature, which is likely contributing to the Housing First research-practice gap to some degree. Future Housing First literature should accurately explain the role of harm reduction when discussing it in the context of Housing First programming, and public agencies promoting Housing First uptake should provide resources for proper implementation and monitor program fidelity to prevent model drift.

  9. Earthquake analysis of structures including structure-soil interaction by a substructure method

    International Nuclear Information System (INIS)

    Chopra, A.K.; Guttierrez, J.A.

    1977-01-01

    A general substructure method for analysis of response of nuclear power plant structures to earthquake ground motion, including the effects of structure-soil interaction, is summarized. The method is applicable to complex structures idealized as finite element systems and the soil region treated as either a continuum, for example as a viscoelastic halfspace, or idealized as a finite element system. The halfspace idealization permits reliable analysis for sites where essentially similar soils extend to large depths and there is no rigid boundary such as soil-rock interface. For sites where layers of soft soil are underlain by rock at shallow depth, finite element idealization of the soil region is appropriate; in this case, the direct and substructure methods would lead to equivalent results but the latter provides the better alternative. Treating the free field motion directly as the earthquake input in the substructure eliminates the deconvolution calculations and the related assumption-regarding type and direction of earthquake waves-required in the direct method. (Auth.)

  10. Global analysis of Solar neutrino oscillation evidence including SNO and implications for Borexino

    CERN Document Server

    Aliani, P; Picariello, M; Torrente-Lujan, E

    2002-01-01

    An updated analysis of all available neutrino oscillation evidence in Solar experiments including the latest $SNO$ data is presented. Predictions for total rates and day-night asymmetry in Borexino are calculated. Our analysis features the use of exhaustive computation of the neutrino oscillation probabilities and the use of an improved statistical $\\chi^2$ minimization. In the framework of two neutrino oscillations we conclude that the best fit to the data is obtained in the LMA region with parameters $(\\Delta m^2, \\tan^2\\theta) = (5.2 \\times 10^{-5} \\eV^2, 0.47)$, ($\\chi^2_{min}/n=0.82$, $n=38$ degrees of freedom). Although less favored, solutions in the LOW and VAC regions are still possible with a reasonable statistical significance. The best possible solution in the SMA region gets as maximum a statistical significance as low as $\\sim 3%$. We study the implications of these results for the prospects of Borexino and the possibility of discriminating between the different solutions. The expected normalized...

  11. Ca analysis: an Excel based program for the analysis of intracellular calcium transients including multiple, simultaneous regression analysis.

    Science.gov (United States)

    Greensmith, David J

    2014-01-01

    Here I present an Excel based program for the analysis of intracellular Ca transients recorded using fluorescent indicators. The program can perform all the necessary steps which convert recorded raw voltage changes into meaningful physiological information. The program performs two fundamental processes. (1) It can prepare the raw signal by several methods. (2) It can then be used to analyze the prepared data to provide information such as absolute intracellular Ca levels. Also, the rates of change of Ca can be measured using multiple, simultaneous regression analysis. I demonstrate that this program performs equally well as commercially available software, but has numerous advantages, namely creating a simplified, self-contained analysis workflow. Copyright © 2013 The Author. Published by Elsevier Ireland Ltd.. All rights reserved.

  12. Electronic document management system analysis report and system plan for the Environmental Restoration Program

    International Nuclear Information System (INIS)

    Frappaolo, C.

    1995-09-01

    Lockheed Martin Energy Systems, Inc. (LMES) has established and maintains Document Management Centers (DMCs) to support Environmental Restoration Program (ER) activities undertaken at three Oak Ridge facilities: Oak Ridge National Laboratory, Oak Ridge K-25 Site, Oak Ridge Y-12 Plant; and two sister sites: Portsmouth Gaseous Diffusion Plant in Portsmouth, Ohio, and Paducah Gaseous Diffusion Plant in Paducah, Kentucky. The role of the DMCs is to receive, store, retrieve, and properly dispose of records. In an effort to make the DMCs run more efficiently and to more proactively manage the records' life cycles from cradle to grave, ER has decided to investigate ways in which Electronic Document Management System (EDMS) technologies can be used to redefine the DMCs and their related processes. Specific goals of this study are tightening control over the ER documents, establishing and enforcing record creation and retention procedures, speeding up access to information, and increasing the accessibility of information. A working pilot of the solution is desired within the next six months. Based on a series of interviews conducted with personnel from each of the DMCs, key management, and individuals representing related projects, it is recommended that ER utilize document management, full-text retrieval, and workflow technologies to improve and automate records management for the ER program. A phased approach to solution implementation is suggested starting with the deployment of an automated storage and retrieval system at Portsmouth. This should be followed with a roll out of the system to the other DMCs, the deployment of a workflow-enabled authoring system at Portsmouth, and a subsequent roll out of this authoring system to the other sites

  13. Data management, documentation and analysis systems in radiation oncology: a multi-institutional survey

    International Nuclear Information System (INIS)

    Kessel, Kerstin A.; Combs, Stephanie E.

    2015-01-01

    Recently, information availability has become more elaborate and widespread, and treatment decisions are based on a multitude of factors. Gathering relevant data, also referred to as Big Data, is therefore critical for reaching the best patient care, and enhancing interdisciplinary and clinical research. Combining patient data from all involved systems is essential to prepare unstructured data for analyses. This demands special coordination in data management. Our study aims to characterize current developments in German-speaking hospital departments and practices. We successfully conducted the survey with the members of the Deutsche Gesellschaft für Radioonkologie (DEGRO). A questionnaire was developed consisting of 17 questions related to data management, documentation and clinical trial analyses, reflecting the clinical topics such as basic patient information, imaging, follow-up information as well as connection of documentation tools with radiooncological treatment planning machines. A total of 44 institutions completed the online survey (University hospitals n = 17, hospitals n = 13, practices/institutes n = 14). University hospitals, community hospitals and private practices are equally equipped concerning IT infrastructure for clinical use. However, private practices have a low interest in research work. All respondents stated the biggest obstacles about introducing a documentation system into their unit lie in funding and support of the central IT departments. Only 27 % (12/44) of responsible persons are specialists for documentation and data management. Our study gives an understanding of the challenges and solutions we need to be looking at for medical data storage. In the future, inter-departmental cross-links will enable the radiation oncology community to generate large-scale analyses. The online version of this article (doi:10.1186/s13014-015-0543-0) contains supplementary material, which is available to authorized users

  14. The more it changes; the more it remains the same: a Foucauldian analysis of Canadian policy documents relevant to student selection for medical school.

    Science.gov (United States)

    Razack, Saleem; Lessard, David; Hodges, Brian D; Maguire, Mary H; Steinert, Yvonne

    2014-05-01

    Calls to increase the demographic representativeness of medical classes to better reflect the diversity of society are part of a growing international trend. Despite this, entry into medical school remains highly competitive and exclusive of marginalized groups. To address these questions, we conducted a Foucauldian discourse analysis of 15 publically available policy documents from the websites of Canadian medical education regulatory bodies, using the concepts of "excellence" (institutional or in an applicant), "diversity," and "equity" to frame the analysis. In most documents, there were appeals to broaden definitions of institutional excellence to include concerns for greater social accountability. Equity concerns tended to be represented as needing to be dealt with by people in positions of authority in order to counter a "hidden curriculum." Diversity was represented as an object of value, situated within a discontinuous history. As a rhetorical strategy, documents invoked complex societal shifts to promote change toward a more humanistic medical education system and profession. "Social accountability" was reified as an all-encompassing solution to most issues of representation. Although the policy documents proclaimed rootedness in an ethos of improving the societal responsiveness of the medical profession, our analysis takes a more critical stance towards the discourses identified. On the basis of our research findings, we question whether these calls may contribute to the maintenance of the specific power relations they seek to address. These conclusions lead us to consider the possibility that the discourses represented in the documents might be reframed to take into account issues of power distribution and its productive and reproductive features. A reframing of discourses could potentially generate greater inclusiveness in policy development processes, and afford disadvantaged and marginalized groups more participatory roles in the discussion.

  15. DOCUMENTATION OF HISTORICAL UNDERGROUND OBJECT IN SKORKOV VILLAGE WITH SELECTED MEASURING METHODS, DATA ANALYSIS AND VISUALIZATION

    Directory of Open Access Journals (Sweden)

    A. Dlesk

    2016-06-01

    Full Text Available The author analyzes current methods of 3D documentation of historical tunnels in Skorkov village, which lies at the Jizera river, approximately 30 km away from Prague. The area is known as a former military camp from Thirty Years’ War in 17th Century. There is an extensive underground compound with one entrance corridor and two transverse, situated approximately 2 to 5 m under the local development. The object has been partly documented by geodetic polar method, intersection photogrammetry, image-based modelling and laser scanning. Data have been analyzed and methods have been compared. Then the 3D model of object has been created and compound with cadastral data, orthophoto, historical maps and digital surface model which was made by photogrammetric method using remotely piloted aircraft system. Then the measuring has been realized with ground penetrating radar. Data have been analyzed and the result compared with real status. All the data have been combined and visualized into one 3D model. Finally, the discussion about advantages and disadvantages of used measuring methods has been livened up. The tested methodology has been also used for other documentation of historical objects in this area. This project has been created as a part of research at EuroGV. s.r.o. Company lead by Ing. Karel Vach CSc. in cooperation with prof. Dr. Ing. Karel Pavelka from Czech Technical University in Prague and Miloš Gavenda, the renovator.

  16. Documents preparation and review

    International Nuclear Information System (INIS)

    1999-01-01

    Ignalina Safety Analysis Group takes active role in assisting regulatory body VATESI to prepare various regulatory documents and reviewing safety reports and other documentation presented by Ignalina NPP in the process of licensing of unit 1. The list of main documents prepared and reviewed is presented

  17. Earthquake analysis of structures including structure-soil interaction by a substructure method

    International Nuclear Information System (INIS)

    Chopra, A.K.; Guttierrez, J.A.

    1977-01-01

    A general substructure method for analysis of response of nuclear power plant structures to earthquake ground motion, including the effects of structure-soil interaction, is summarized. The method is applicable to complex structures idealized as finite element systems and the soil region treated as either a continuum, for example as a viscoelastic halfspace, or idealized as a finite element system. The halfspace idealization permits reliable analysis for sites where essentially similar soils extend to large depths and there is no rigid boundary such as soil-rock interface. For sites where layers of soft soil are underlain by rock at shallow depth, finite element idealization of the soil region is appropriate; in this case, the direct and substructure methods would lead to equivalent results but the latter provides the better alternative. Treating the free field motion directly as the earthquake input in the substructure method eliminates the deconvolution calculations and the related assumption -regarding type and direction of earthquake waves- required in the direct method. The substructure method is computationally efficient because the two substructures-the structure and the soil region- are analyzed separately; and, more important, it permits taking advantage of the important feature that response to earthquake ground motion is essentially contained in the lower few natural modes of vibration of the structure on fixed base. For sites where essentially similar soils extend to large depths and there is no obvious rigid boundary such as a soil-rock interface, numerical results for earthquake response of a nuclear reactor structure are presented to demonstrate that the commonly used finite element method may lead to unacceptable errors; but the substructure method leads to reliable results

  18. Piping failure analysis for the Korean nuclear piping including the effect of in-service inspection

    Energy Technology Data Exchange (ETDEWEB)

    Choi, S.Y. [Korea Atomic Energy Research Inst.(KAERI), Daejeon (Korea); Choi, Y.H. [Korea Inst. of Nuclear Safety(KINS), Daejeon (Korea)

    2004-07-01

    The purposes of this paper are to perform piping failure analysis for the failed safety class piping in Korean nuclear power plants(NPPs) and evaluate the effect of an in-service inspection(ISI) on the piping failure probability. For data collection, a database for piping failure events was constructed with 135 data fields including population data, event data, and service history data. A total of 6 kinds of events with 25 failure cases up to June 30, 2003 were identified from Korean NPPs. The failed systems were main feedwater system, CVCS, primary sampling system, essential service water system, and CANDU purification system. Piping failure analyses such as evaluation of the impact on nuclear safety and piping integrity and the root cause analysis were performed and the piping failure frequencies for the failed piping were calculated by using population data. The result showed that although the integrity was not maintained in the failed piping, the safety of the plants was maintained for all the events. And the root causes of the events were analyzed as FAC, vibration, thermal fatigue, corrosion, and/or an improper weld joint. The piping failure frequencies ranged from 6.08E-5/Cr-Yr to 1.15E-3/Cr-Yr for the events. According to the ASME Code sec. XI requirements, the small bore piping less than the nominal diameter of 4 inch is exempt from ISI. There, however, were many piping failures reported in the small bore piping. The effect of ISI considering the pipe size on the piping failure probability was investigated by using the Win-PRAISE program based on probabilistic fracture mechanics. The results showed that there is no significant difference between the small and large bore piping from the viewpoint of the ISI effect on the piping failure probability. It means that ISI for a small bore piping is recommended as well as the large bore piping. (orig.)

  19. Performance analysis of the MHD-steam combined cycle, including the influence of cost

    Energy Technology Data Exchange (ETDEWEB)

    Berry, G. F.; Dennis, C. B.

    1980-08-01

    The MHD Systems group of the ANL Engineering Division is conducting overall system studies, utilizing the computer simulation code that has been developed at ANL. This analytical investigation is exploring a range of possible performance variables, in order to determine the sensitivity of a specific plant design to variation in key system parameters and, ultimately, to establish probable system performance limits. The comprehensive computer code that has been developed for this task will analyze and simulate an MHD power plant for any number of different configurations, and will hold constraints automatically while conducting either sensitivity studies or optimization. A summary of a sensitivity analysis conducted for a combined cycle, MHD-steam power plant is presented. The influence of several of the more important systems parameters were investigated in a systematic fashion, and the results are presented in graphical form. The report is divided into four sections. Following the introduction, the second section describes in detail the results of a validation study conducted to insure that the code is functioning correctly. The third section includes a description of the ANL cost algorithm and a detailed comparison between the ANL cost results and published OCMHD cost information. it is further demonstrated in this section that good agreement is obtained for the calculated cost of electricity. The fourth section is a sensitivity study and optimization for a specific OCMHD configuration over several key plant parameters.

  20. Information management for global environmental change, including the Carbon Dioxide Information Analysis Center

    Energy Technology Data Exchange (ETDEWEB)

    Stoss, F.W. [Oak Ridge National Lab., TN (United States). Carbon Dioxide Information Analysis Center

    1994-06-01

    The issue of global change is international in scope. A body of international organizations oversees the worldwide coordination of research and policy initiatives. In the US the National Science and Technology Council (NSTC) was established in November of 1993 to provide coordination of science, space, and technology policies throughout the federal government. NSTC is organized into nine proposed committees. The Committee on Environmental and Natural Resources (CERN) oversees the US Department of Energy`s Global Change Research Program (USGCRP). As part of the USGCRP, the US Department of Energy`s Global Change Research Program aims to improve the understanding of Earth systems and to strengthen the scientific basis for the evaluation of policy and government action in response to potential global environmental changes. This paper examines the information and data management roles of several international and national programs, including Oak Ridge National Laboratory`s (ORNL`s) global change information programs. An emphasis will be placed on the Carbon Dioxide Information Analysis Center (CDIAC), which also serves as the World Data Center-A for Atmospheric Trace Gases.

  1. Corporate social responsibility and access to policy élites: an analysis of tobacco industry documents.

    Science.gov (United States)

    Fooks, Gary J; Gilmore, Anna B; Smith, Katherine E; Collin, Jeff; Holden, Chris; Lee, Kelley

    2011-08-01

    Recent attempts by large tobacco companies to represent themselves as socially responsible have been widely dismissed as image management. Existing research supports such claims by pointing to the failings and misleading nature of corporate social responsibility (CSR) initiatives. However, few studies have focused in depth on what tobacco companies hoped to achieve through CSR or reflected on the extent to which these ambitions have been realised. Iterative searching relating to CSR strategies was undertaken of internal British American Tobacco (BAT) documents, released through litigation in the US. Relevant documents (764) were indexed and qualitatively analysed. In the past decade, BAT has actively developed a wide-ranging CSR programme. Company documents indicate that one of the key aims of this programme was to help the company secure access to policymakers and, thereby, increase the company's chances of influencing policy decisions. Taking the UK as a case study, this paper demonstrates the way in which CSR can be used to renew and maintain dialogue with policymakers, even in ostensibly unreceptive political contexts. In practice, the impact of this political use of CSR is likely to be context specific; depending on factors such as policy élites' understanding of the credibility of companies as a reliable source of information. The findings suggest that tobacco company CSR strategies can enable access to and dialogue with policymakers and provide opportunities for issue definition. CSR should therefore be seen as a form of corporate political activity. This underlines the need for broad implementation of Article 5.3 of the Framework Convention on Tobacco Control. Measures are needed to ensure transparency of interactions between all parts of government and the tobacco industry and for policy makers to be made more aware of what companies hope to achieve through CSR.

  2. Corporate social responsibility and access to policy élites: an analysis of tobacco industry documents.

    Directory of Open Access Journals (Sweden)

    Gary J Fooks

    2011-08-01

    Full Text Available Recent attempts by large tobacco companies to represent themselves as socially responsible have been widely dismissed as image management. Existing research supports such claims by pointing to the failings and misleading nature of corporate social responsibility (CSR initiatives. However, few studies have focused in depth on what tobacco companies hoped to achieve through CSR or reflected on the extent to which these ambitions have been realised.Iterative searching relating to CSR strategies was undertaken of internal British American Tobacco (BAT documents, released through litigation in the US. Relevant documents (764 were indexed and qualitatively analysed. In the past decade, BAT has actively developed a wide-ranging CSR programme. Company documents indicate that one of the key aims of this programme was to help the company secure access to policymakers and, thereby, increase the company's chances of influencing policy decisions. Taking the UK as a case study, this paper demonstrates the way in which CSR can be used to renew and maintain dialogue with policymakers, even in ostensibly unreceptive political contexts. In practice, the impact of this political use of CSR is likely to be context specific; depending on factors such as policy élites' understanding of the credibility of companies as a reliable source of information.The findings suggest that tobacco company CSR strategies can enable access to and dialogue with policymakers and provide opportunities for issue definition. CSR should therefore be seen as a form of corporate political activity. This underlines the need for broad implementation of Article 5.3 of the Framework Convention on Tobacco Control. Measures are needed to ensure transparency of interactions between all parts of government and the tobacco industry and for policy makers to be made more aware of what companies hope to achieve through CSR.

  3. Corporate Social Responsibility and Access to Policy Élites: An Analysis of Tobacco Industry Documents

    Science.gov (United States)

    Fooks, Gary J.; Gilmore, Anna B.; Smith, Katherine E.; Collin, Jeff; Holden, Chris; Lee, Kelley

    2011-01-01

    Background Recent attempts by large tobacco companies to represent themselves as socially responsible have been widely dismissed as image management. Existing research supports such claims by pointing to the failings and misleading nature of corporate social responsibility (CSR) initiatives. However, few studies have focused in depth on what tobacco companies hoped to achieve through CSR or reflected on the extent to which these ambitions have been realised. Methods and Findings Iterative searching relating to CSR strategies was undertaken of internal British American Tobacco (BAT) documents, released through litigation in the US. Relevant documents (764) were indexed and qualitatively analysed. In the past decade, BAT has actively developed a wide-ranging CSR programme. Company documents indicate that one of the key aims of this programme was to help the company secure access to policymakers and, thereby, increase the company's chances of influencing policy decisions. Taking the UK as a case study, this paper demonstrates the way in which CSR can be used to renew and maintain dialogue with policymakers, even in ostensibly unreceptive political contexts. In practice, the impact of this political use of CSR is likely to be context specific; depending on factors such as policy élites' understanding of the credibility of companies as a reliable source of information. Conclusions The findings suggest that tobacco company CSR strategies can enable access to and dialogue with policymakers and provide opportunities for issue definition. CSR should therefore be seen as a form of corporate political activity. This underlines the need for broad implementation of Article 5.3 of the Framework Convention on Tobacco Control. Measures are needed to ensure transparency of interactions between all parts of government and the tobacco industry and for policy makers to be made more aware of what companies hope to achieve through CSR. Please see later in the article for the Editors

  4. Analysis of advanced european nuclear fuel cycle scenarios including transmutation and economical estimates

    International Nuclear Information System (INIS)

    Merino Rodriguez, I.; Alvarez-Velarde, F.; Martin-Fuertes, F.

    2013-01-01

    In this work the transition from the existing Light Water Reactors (LWR) to the advanced reactors is analyzed, including Generation III+ reactors in a European framework. Four European fuel cycle scenarios involving transmutation options have been addressed. The first scenario (i.e., reference) is the current fleet using LWR technology and open fuel cycle. The second scenario assumes a full replacement of the initial fleet with Fast Reactors (FR) burning U-Pu MOX fuel. The third scenario is a modification of the second one introducing Minor Actinide (MA) transmutation in a fraction of the FR fleet. Finally, in the fourth scenario, the LWR fleet is replaced using FR with MOX fuel as well as Accelerator Driven Systems (ADS) for MA transmutation. All scenarios consider an intermediate period of GEN-III+ LWR deployment and they extend for a period of 200 years looking for equilibrium mass flows. The simulations were made using the TR-EVOL code, a tool for fuel cycle studies developed by CIEMAT. The results reveal that all scenarios are feasible according to nuclear resources demand (U and Pu). Concerning to no transmutation cases, the second scenario reduces considerably the Pu inventory in repositories compared to the reference scenario, although the MA inventory increases. The transmutation scenarios show that elimination of the LWR MA legacy requires on one hand a maximum of 33% fraction (i.e., a peak value of 26 FR units) of the FR fleet dedicated to transmutation (MA in MOX fuel, homogeneous transmutation). On the other hand a maximum number of ADS plants accounting for 5% of electricity generation are predicted in the fourth scenario (i.e., 35 ADS units). Regarding the economic analysis, the estimations show an increase of LCOE (Levelized cost of electricity) - averaged over the whole period - with respect to the reference scenario of 21% and 29% for FR and FR with transmutation scenarios respectively, and 34% for the fourth scenario. (authors)

  5. Analysis of compatibility of current Czech initial documentation in the area of technical assurance of nuclear safety with the requirements of the EUR document

    International Nuclear Information System (INIS)

    Zdebor, J.; Zdebor, R.; Kratochvil, L.

    2001-11-01

    The publication is structured as follows: Description of existing documentation. General requirements, goals, principles and design principles: Documents being compared; Method of comparison; Results and partial evaluation of comparison of requirements between EUR and Czech regulations (basic goals and safety philosophy; quantitative safety objectives; basic design requirements; extended design requirements; external and internal threats; technical requirements; site conditions); Summary of the comparison of safety requirements. Comparison of requirements for the systems: Requirements for the nuclear reactor unit systems; Barrier systems (fuel system; reactor cooling system; containment system); Remaining systems (control systems; protection systems; coolant makeup and purification system; residual heat removal system; emergency cooling system; power systems); Common technical requirements for systems (technical requirements for systems; internal and external events). (P.A.)

  6. Development of knowledge models by linguistic analysis of lexical relationships in technical documents

    International Nuclear Information System (INIS)

    Seguela, Patrick

    2001-01-01

    This research thesis addresses the problem of knowledge acquisition and structuring from technical texts, and the use of this knowledge in the development of models. The author presents the Cameleon method which aims at extracting binary lexical relationships from technical texts by identifying linguistic markers. The relevance of this method is assessed in the case of four different corpuses: a written technical corpus, an oral technical corpus, a corpus of texts of instructions, and a corpus of academic texts. The author reports the development of a model of representation of knowledge of a specific field by using lexical relationships. The method is then applied to develop a model used in document search within a knowledge management system [fr

  7. Perspectives: Using Historical Documents To Think about NIF Issues.

    Science.gov (United States)

    National Archives and Records Service (GSA), Washington, DC.

    The purpose of using historical documents in the classroom is to generate and enhance discussion by providing a historical perspective for issues. Five documents are included in this packet and are to be used as a supplemental material for the National Issues Forum (NIF) topics. Issues raised include (1) an analysis of the documents and (2)…

  8. A systematic review including meta-analysis of work environment and depressive symptoms.

    Science.gov (United States)

    Theorell, Töres; Hammarström, Anne; Aronsson, Gunnar; Träskman Bendz, Lil; Grape, Tom; Hogstedt, Christer; Marteinsdottir, Ina; Skoog, Ingmar; Hall, Charlotte

    2015-08-01

    Depressive symptoms are potential outcomes of poorly functioning work environments. Such symptoms are frequent and cause considerable suffering for the employees as well as financial loss for the employers. Accordingly good prospective studies of psychosocial working conditions and depressive symptoms are valuable. Scientific reviews of such studies have pointed at methodological difficulties but still established a few job risk factors. Those reviews were published some years ago. There is need for an updated systematic review using the GRADE system. In addition, gender related questions have been insufficiently reviewed. Inclusion criteria for the studies published 1990 to June 2013: 1. European and English speaking countries. 2. Quantified results describing the relationship between exposure (psychosocial or physical/chemical) and outcome (standardized questionnaire assessment of depressive symptoms or interview-based clinical depression). 3. Prospective or comparable case-control design with at least 100 participants. 4. Assessments of exposure (working conditions) and outcome at baseline and outcome (depressive symptoms) once again after follow-up 1-5 years later. 5. Adjustment for age and adjustment or stratification for gender. Studies filling inclusion criteria were subjected to assessment of 1.) relevance and 2.) quality using predefined criteria. Systematic review of the evidence was made using the GRADE system. When applicable, meta-analysis of the magnitude of associations was made. Consistency of findings was examined for a number of possible confounders and publication bias was discussed. Fifty-nine articles of high or medium high scientific quality were included. Moderately strong evidence (grade three out of four) was found for job strain (high psychological demands and low decision latitude), low decision latitude and bullying having significant impact on development of depressive symptoms. Limited evidence (grade two) was shown for psychological

  9. High Resolution Proteomic Analysis of the Cervical Cancer Cell Lines Secretome Documents Deregulation of Multiple Proteases.

    Science.gov (United States)

    Pappa, Kalliopi I; Kontostathi, Georgia; Makridakis, Manousos; Lygirou, Vasiliki; Zoidakis, Jerome; Daskalakis, George; Anagnou, Nicholas P

    2017-01-01

    Oncogenic infection by HPV, eventually leads to cervical carcinogenesis, associated by deregulation of specific pathways and protein expression at the intracellular and secretome level. Thus, secretome analysis can elucidate the biological mechanisms contributing to cervical cancer. In the present study we systematically analyzed its constitution in four cervical cell lines employing a highly sensitive proteomic technology coupled with bioinformatics analysis. LC/MS-MS proteomics and bioinformatics analysis were performed in the secretome of four informative cervical cell lines SiHa (HPV16 + ), HeLa (HPV18 + ), C33A (HPV - ) and HCK1T (normal). The proteomic pattern of each cancer cell line compared to HCK1T was identified and a detailed bioinformatics analysis disclosed inhibition of matrix metalloproteases in cancer cell lines. This prediction was further confirmed via zymography for MMP-2 and MMP-9, western blot analysis for ADAM10 and by MRM for TIMP1. The differential expression of important secreted proteins such as CATD, FUCA1 and SOD2 was also confirmed by western blot analysis. MRM-targeted proteomics analysis confirmed the differential expression of CATD, CATB, SOD2, QPCT and NEU1. High resolution proteomics analysis of cervical cancer secretome revealed significantly deregulated biological processes and proteins implicated in cervical carcinogenesis. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  10. Comparative study of plans for integrated residue management of construction: an analysis documental

    Directory of Open Access Journals (Sweden)

    Jorge Henrique e Silva Júnior

    2014-02-01

    Full Text Available Objetivo: o presente trabalho faz um estudo comparativo dos Planos integrados de quatro cidades, destacando os pontos que estão de acordo com a resolução 307/2002 do CONAMA. Método: Trata-se de uma pesquisa bibliográfica e documental tendo como fontes artigos científicos e os Planos Integrados de Gerenciamento de Resíduos Sólidos da Construção Civil de cinco cidades brasileiras: Curitiba, Cuiabá, Florianópolis, Rio de Janeiro e São Paulo. Resultados: A resolução prevê o Plano Integrado de Gerenciamento de Resíduos da Construção Civil, como instrumento para implementação da gestão dos resíduos da construção civil, que deve ser elaborado pelos municípios. Muitas capitais ainda não elaboraram seus Planos Integrados de Gerenciamento de Resíduos da Construção Civil. Conclusão: O Plano Integrado de Gerenciamento dos Resíduos da Construção Civil é de grande importância, pois esses resíduos trazem inúmeros problemas ambientais e de saúde.

  11. The right to the city and International Urban Agendas: a document analysis.

    Science.gov (United States)

    Andrade, Elisabete Agrela de; Franceschini, Maria Cristina Trousdell

    2017-12-01

    Considering social, economic and demographic issues, living in the city implies inadequate living conditions, social exclusion, inequities and other problems to the population. At the same time, the city is a setting of cultural, social and affective production. As a result, there is a need to reflect on the right to the city and its relationship with promoting the health of its inhabitants. To that effect, urban agendas have been developed to address the city's ambiguity. This paper aims to analyze four of these agendas through the lenses of Health Promotion. A qualitative document review approach was conducted on urban agendas proposed by international organizations and applied to the Brazilian context: Healthy Cities, Sustainable Cities, Smart Cities and Educating Cities. Results indicate some level of effort by the analyzed agendas to assume social participation, intersectoriality and the territory as central to addressing exclusion and inequities. However, more in-depth discussions are required on each of these concepts. We conclude that urban agendas can contribute greatly toward consolidating the right to the city, provided that their underpinning concepts are critically comprehended.

  12. Slavery Service Accounting Practices in Brazil: A Bibliographic and Document Analysis

    Directory of Open Access Journals (Sweden)

    Adriana Rodrigues Silva

    2014-12-01

    Full Text Available This study focuses on the social and economic aspects and institutional relationships that determined a unique pattern of inequality. We aim to examine the particular role of accounting as a practice used to dehumanize an entire class of people. The primary purpose of this study is not to examine slavery's profitability but rather to identify how accounting practices served slavery. A qualitative research method is applied in this study. Regarding technical procedures, this study makes use of bibliographic and documentary sources. For the purpose of this investigation, and in accordance with bibliographic and documentary research methods, we analyze scientific articles, books and documents from the Brazilian National Archive, the Brazilian Historic and Geographic Institute and the Brazilian National Library Foundation. In light of what was discovered through the study's development, we can consider accounting as a tool that is more active than passive and, therefore, as a tool that was used to support the slave regime. In essence, accounting was used to convert a human's qualitative attributes into a limited number of categories (age, gender, race, through which slaves were differentiated and monetized to facilitate commercial trafficking. We believe that accounting practices facilitated slave trading, conversion and exploitation, procedures that completely ignored qualitative and human dimensions of slavery. Opportunities for future studies on accounting in the slave period, as is the case of other oppressive regimes, are infinite, especially in the case of Brazil.

  13. Space station system analysis study. Part 3: Documentation. Volume 2: Technical report. [structural design and construction

    Science.gov (United States)

    1977-01-01

    An analysis of construction operation is presented as well as power system sizing requirements. Mission hardware requirements are reviewed in detail. Space construction base and design configurations are also examined.

  14. Microsoft Academic Automatic Document Searches: Accuracy for Journal Articles and Suitability for Citation Analysis

    OpenAIRE

    Thelwall, Mike

    2017-01-01

    Microsoft Academic is a free academic search engine and citation index that is similar to Google Scholar but can be automatically queried. Its data is potentially useful for bibliometric analysis if it is possible to search effectively for individual journal articles. This article compares different methods to find journal articles in its index by searching for a combination of title, authors, publication year and journal name and uses the results for the widest published correlation analysis...

  15. Probabilistic and deterministic soil structure interaction analysis including ground motion incoherency effects

    Energy Technology Data Exchange (ETDEWEB)

    Elkhoraibi, T., E-mail: telkhora@bechtel.com; Hashemi, A.; Ostadan, F.

    2014-04-01

    Soil-structure interaction (SSI) is a major step for seismic design of massive and stiff structures typical of the nuclear facilities and civil infrastructures such as tunnels, underground stations, dams and lock head structures. Currently most SSI analyses are performed deterministically, incorporating limited range of variation in soil and structural properties and without consideration of the ground motion incoherency effects. This often leads to overestimation of the seismic response particularly the In-Structure-Response Spectra (ISRS) with significant impositions of design and equipment qualification costs, especially in the case of high-frequency sensitive equipment at stiff soil or rock sites. The reluctance to incorporate a more comprehensive probabilistic approach is mainly due to the fact that the computational cost of performing probabilistic SSI analysis even without incoherency function considerations has been prohibitive. As such, bounding deterministic approaches have been preferred by the industry and accepted by the regulatory agencies. However, given the recently available and growing computing capabilities, the need for a probabilistic-based approach to the SSI analysis is becoming clear with the advances in performance-based engineering and the utilization of fragility analysis in the decision making process whether by the owners or the regulatory agencies. This paper demonstrates the use of both probabilistic and deterministic SSI analysis techniques to identify important engineering demand parameters in the structure. A typical nuclear industry structure is used as an example for this study. The system is analyzed for two different site conditions: rock and deep soil. Both deterministic and probabilistic SSI analysis approaches are performed, using the program SASSI, with and without ground motion incoherency considerations. In both approaches, the analysis begins at the hard rock level using the low frequency and high frequency hard rock

  16. Static aeroelastic analysis including geometric nonlinearities based on reduced order model

    Directory of Open Access Journals (Sweden)

    Changchuan Xie

    2017-04-01

    Full Text Available This paper describes a method proposed for modeling large deflection of aircraft in nonlinear aeroelastic analysis by developing reduced order model (ROM. The method is applied for solving the static aeroelastic and static aeroelastic trim problems of flexible aircraft containing geometric nonlinearities; meanwhile, the non-planar effects of aerodynamics and follower force effect have been considered. ROMs are computational inexpensive mathematical representations compared to traditional nonlinear finite element method (FEM especially in aeroelastic solutions. The approach for structure modeling presented here is on the basis of combined modal/finite element (MFE method that characterizes the stiffness nonlinearities and we apply that structure modeling method as ROM to aeroelastic analysis. Moreover, the non-planar aerodynamic force is computed by the non-planar vortex lattice method (VLM. Structure and aerodynamics can be coupled with the surface spline method. The results show that both of the static aeroelastic analysis and trim analysis of aircraft based on structure ROM can achieve a good agreement compared to analysis based on the FEM and experimental result.

  17. Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture

    Science.gov (United States)

    Sanfilippo, Antonio [Richland, WA; Calapristi, Augustin J [West Richland, WA; Crow, Vernon L [Richland, WA; Hetzler, Elizabeth G [Kennewick, WA; Turner, Alan E [Kennewick, WA

    2009-12-22

    Document clustering methods, document cluster label disambiguation methods, document clustering apparatuses, and articles of manufacture are described. In one aspect, a document clustering method includes providing a document set comprising a plurality of documents, providing a cluster comprising a subset of the documents of the document set, using a plurality of terms of the documents, providing a cluster label indicative of subject matter content of the documents of the cluster, wherein the cluster label comprises a plurality of word senses, and selecting one of the word senses of the cluster label.

  18. The total assessment profile, volume 2. [including societal impact, cost effectiveness, and economic analysis

    Science.gov (United States)

    Leininger, G.; Jutila, S.; King, J.; Muraco, W.; Hansell, J.; Lindeen, J.; Franckowiak, E.; Flaschner, A.

    1975-01-01

    Appendices are presented which include discussions of interest formulas, factors in regionalization, parametric modeling of discounted benefit-sacrifice streams, engineering economic calculations, and product innovation. For Volume 1, see .

  19. Selection Component Analysis of Natural Polymorphisms using Population Samples Including Mother-Offspring Combinations, II

    DEFF Research Database (Denmark)

    Jarmer, Hanne Østergaard; Christiansen, Freddy Bugge

    1981-01-01

    Population samples including mother-offspring combinations provide information on the selection components: zygotic selection, sexual selection, gametic seletion and fecundity selection, on the mating pattern, and on the deviation from linkage equilibrium among the loci studied. The theory...

  20. Documentation of Hanford Site independent review of the Hanford Waste Vitrification Plant Preliminary Safety Analysis Report

    International Nuclear Information System (INIS)

    Herborn, D.I.

    1993-11-01

    Westinghouse Hanford Company (WHC) is the Integrating Contractor for the Hanford Waste Vitrification Plant (HWVP) Project, and as such is responsible for preparation of the HWVP Preliminary Safety Analysis Report (PSAR). The HWVP PSAR was prepared pursuant to the requirements for safety analyses contained in US Department of Energy (DOE) Orders 4700.1, Project Management System (DOE 1987); 5480.5, Safety of Nuclear Facilities (DOE 1986a); 5481.lB, Safety Analysis and Review System (DOE 1986b) which was superseded by DOE order 5480-23, Nuclear Safety Analysis Reports, for nuclear facilities effective April 30, 1992 (DOE 1992); and 6430.lA, General Design Criteria (DOE 1989). The WHC procedures that, in large part, implement these DOE requirements are contained in WHC-CM-4-46, Nonreactor Facility Safety Analysis Manual. This manual describes the overall WHC safety analysis process in terms of requirements for safety analyses, responsibilities of the various contributing organizations, and required reviews and approvals

  1. MetaComp: comprehensive analysis software for comparative meta-omics including comparative metagenomics.

    Science.gov (United States)

    Zhai, Peng; Yang, Longshu; Guo, Xiao; Wang, Zhe; Guo, Jiangtao; Wang, Xiaoqi; Zhu, Huaiqiu

    2017-10-02

    During the past decade, the development of high throughput nucleic sequencing and mass spectrometry analysis techniques have enabled the characterization of microbial communities through metagenomics, metatranscriptomics, metaproteomics and metabolomics data. To reveal the diversity of microbial communities and interactions between living conditions and microbes, it is necessary to introduce comparative analysis based upon integration of all four types of data mentioned above. Comparative meta-omics, especially comparative metageomics, has been established as a routine process to highlight the significant differences in taxon composition and functional gene abundance among microbiota samples. Meanwhile, biologists are increasingly concerning about the correlations between meta-omics features and environmental factors, which may further decipher the adaptation strategy of a microbial community. We developed a graphical comprehensive analysis software named MetaComp comprising a series of statistical analysis approaches with visualized results for metagenomics and other meta-omics data comparison. This software is capable to read files generated by a variety of upstream programs. After data loading, analyses such as multivariate statistics, hypothesis testing of two-sample, multi-sample as well as two-group sample and a novel function-regression analysis of environmental factors are offered. Here, regression analysis regards meta-omic features as independent variable and environmental factors as dependent variables. Moreover, MetaComp is capable to automatically choose an appropriate two-group sample test based upon the traits of input abundance profiles. We further evaluate the performance of its choice, and exhibit applications for metagenomics, metaproteomics and metabolomics samples. MetaComp, an integrative software capable for applying to all meta-omics data, originally distills the influence of living environment on microbial community by regression analysis

  2. Draft Regulatory Analysis. Technical support document No. 1: energy efficiency standards for consumer products

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-06-01

    A Draft Regulatory Analysis is presented that describes the analyses performed by DOE to arrive at proposed energy efficiency standards for refrigerators and refrigerator-freezers, freezers, clothes dryers, water heaters, room air conditioners, kitchen ranges and ovens, central air conditioners (cooling only), and furnaces. Standards for dishwashers, television sets, clothes washers, and humidifiers and dehumidifiders are required to be published in the Federal Register no later than December 1981. Standards for central air conditioners (heat pumps) and home heating equipment are to be published in the Federal Register no later than January 1982. Accordingly, these products are not discussed in this Draft Regulatory Analysis.

  3. Development of a traceability analysis method based on case grammar for NPP requirement documents written in Korean language

    International Nuclear Information System (INIS)

    Yoo, Yeong Jae; Seong, Poong Hyun; Kim, Man Cheol

    2004-01-01

    Software inspection is widely believed to be an effective method for software verification and validation (V and V). However, software inspection is labor-intensive and, since it uses little technology, software inspection is viewed upon as unsuitable for a more technology-oriented development environment. Nevertheless, software inspection is gaining in popularity. KAIST Nuclear I and C and Information Engineering Laboratory (NICIEL) has developed software management and inspection support tools, collectively named 'SIS-RT.' SIS-RT is designed to partially automate the software inspection processes. SIS-RT supports the analyses of traceability between a given set of specification documents. To make SIS-RT compatible for documents written in Korean, certain techniques in natural language processing have been studied. Among the techniques considered, case grammar is most suitable for analyses of the Korean language. In this paper, we propose a methodology that uses a case grammar approach to analyze the traceability between documents written in Korean. A discussion regarding some examples of such an analysis will follow

  4. Dipole model analysis of highest precision HERA data, including very low Q2's

    International Nuclear Information System (INIS)

    Luszczak, A.; Kowalski, H.

    2016-12-01

    We analyse, within a dipole model, the final, inclusive HERA DIS cross section data in the low χ region, using fully correlated errors. We show, that these highest precision data are very well described within the dipole model framework starting from Q 2 values of 3.5 GeV 2 to the highest values of Q 2 =250 GeV 2 . To analyze the saturation effects we evaluated the data including also the very low 0.35including this region show a preference of the saturation ansatz.

  5. Documentation Service

    International Nuclear Information System (INIS)

    Charnay, J.; Chosson, L.; Croize, M.; Ducloux, A.; Flores, S.; Jarroux, D.; Melka, J.; Morgue, D.; Mottin, C.

    1998-01-01

    This service assures the treatment and diffusion of the scientific information and the management of the scientific production of the institute as well as the secretariat operation for the groups and services of the institute. The report on documentation-library section mentions: the management of the documentation funds, search in international databases (INIS, Current Contents, Inspects), Pret-Inter service which allows accessing documents through DEMOCRITE network of IN2P3. As realizations also mentioned are: the setup of a video, photo database, the Web home page of the institute's library, follow-up of digitizing the document funds by integrating the CD-ROMs and diskettes, electronic archiving of the scientific production, etc

  6. Experiences and Outcomes of Preschool Physical Education: An Analysis of Developmental Discourses in Scottish Curricular Documentation

    Science.gov (United States)

    McEvilly, Nollaig

    2014-01-01

    This article provides an analysis of developmental discourses underpinning preschool physical education in Scotland's Curriculum for Excellence. Implementing a post-structural perspective, the article examines the preschool experiences and outcomes related to physical education as presented in the Curriculum for Excellence "health and…

  7. Using the Front Page of "The Wall Street Journal" to Teach Document Design and Audience Analysis.

    Science.gov (United States)

    Moore, Patrick

    1989-01-01

    Explains an assignment for the audience analysis segment of a business writing course which compares the front page design of "The Wall Street Journal" with that of a local daily newspaper in order to emphasize the use of design devices in effectively writing to busy people. (SR)

  8. Analysis: including visually impaired participants in validation design studies of diabetes technology.

    Science.gov (United States)

    Uslan, Mark; Blubaugh, Morgan

    2010-09-01

    In an article in this issue of Journal of Diabetes Science and Technology, Sherwyn Schwartz, M.D., presents a study to validate the design of the ClikSTAR® insulin pen from sanofi-aventis and demonstrates that the device can be used correctly by participants with diabetes. Concern with this article lies with the selection of participants, which was meant to reflect the intended audience for the insulin pen device but does not address the inclusion of visually impaired individuals, who comprise over 20% of the adult diabetes population. Visually impaired individuals need to be included as part of the intended audience for insulin administration technology, and manufacturers of these devices need to design their products for safe use by all people, including those who are visually impaired. The study demonstrated successful use of the ClikSTAR insulin pen in a population that did not include subjects with severe visual impairment. We believe that future validation studies for insulin administration technology should also include samples of visually impaired users and that visually impaired patients will embrace the use of insulin pens designed with their needs in mind. © 2010 Diabetes Technology Society.

  9. A Comparative Analysis regarding Pictures Included in Secondary School Geography Textbooks Taught in Turkey

    Science.gov (United States)

    Yasar, Okan; Seremet, Mehmet

    2007-01-01

    This study brings in a comparative approach regarding pictures involved in secondary school (14-17 ages) textbooks taught in Turkey. In this respect, following the classification of pictures (line drawings and photographs) included in secondary school education geography textbooks, evaluation of the photographs in books in question in terms of…

  10. Computerising documentation

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The nuclear power generation industry is faced with public concern and government pressures over safety, efficiency and risk. Operators throughout the industry are addressing these issues with the aid of a new technology - technical document management systems (TDMS). Used for strategic and tactical advantage, the systems enable users to scan, archive, retrieve, store, edit, distribute worldwide and manage the huge volume of documentation (paper drawings, CAD data and film-based information) generated in building, maintaining and ensuring safety in the UK's power plants. The power generation industry has recognized that the management and modification of operation critical information is vital to the safety and efficiency of its power plants. Regulatory pressure from the Nuclear Installations Inspectorate (NII) to operate within strict safety margins or lose Site Licences has prompted the need for accurate, up-to-data documentation. A document capture and management retrieval system provides a powerful cost-effective solution, giving rapid access to documentation in a tightly controlled environment. The computerisation of documents and plans is discussed in this article. (Author)

  11. Cost-Effectiveness Analysis of the 2009 and 2012 IECC Residential Provisions – Technical Support Document

    Energy Technology Data Exchange (ETDEWEB)

    Mendon, Vrushali V.; Lucas, Robert G.; Goel, Supriya

    2012-12-04

    This analysis was conducted by Pacific Northwest National Laboratory (PNNL) in support of the U.S. Department of Energy’s (DOE) Building Energy Codes Program (BECP). DOE supports the development and adoption of efficient residential and commercial building energy codes. These codes set the minimum requirements for energy efficient building design and construction and ensure energy savings on a national level. This analysis focuses on one and two family dwellings, townhomes, and low-rise multifamily residential buildings. For these buildings, the basis of the energy codes is the International Energy Conservation Code (IECC). This report does not address commercial and high-rise residential buildings, which reference ANSI/ASHRAE/IES Standard 90.1.

  12. Technical Requirements Analysis and Control Systems (TRACS) Initial Operating Capability (IOC) documentation

    Science.gov (United States)

    Hammond, Dana P.

    1991-01-01

    The Technical Requirements Analysis and Control Systems (TRACS) software package is described. TRACS offers supplemental tools for the analysis, control, and interchange of project requirements. This package provides the fundamental capability to analyze and control requirements, serves a focal point for project requirements, and integrates a system that supports efficient and consistent operations. TRACS uses relational data base technology (ORACLE) in a stand alone or in a distributed environment that can be used to coordinate the activities required to support a project through its entire life cycle. TRACS uses a set of keyword and mouse driven screens (HyperCard) which imposes adherence through a controlled user interface. The user interface provides an interactive capability to interrogate the data base and to display or print project requirement information. TRACS has a limited report capability, but can be extended with PostScript conventions.

  13. Probabilistic risk assessment course documentation. Volume 5. System reliability and analysis techniques Session D - quantification

    International Nuclear Information System (INIS)

    Lofgren, E.V.

    1985-08-01

    This course in System Reliability and Analysis Techniques focuses on the probabilistic quantification of accident sequences and the link between accident sequences and consequences. Other sessions in this series focus on the quantification of system reliability and the development of event trees and fault trees. This course takes the viewpoint that event tree sequences or combinations of system failures and success are available and that Boolean equations for system fault trees have been developed and are available. 93 figs., 11 tabs

  14. The advanced scenario analysis for performance assessment of geological disposal. Pt. 3. Main document

    International Nuclear Information System (INIS)

    Ohkubo, Hiroo

    2004-02-01

    In 'H12 Project to Establish Technical Basis for HLW Disposal in Japan' an approach that is based on an international consensus was adopted to develop scenarios to be considered in performance assessment. Adequacy of the approach was, in general term, appreciated through the peer review. However it was also suggested that there are issues related to improving transparency and traceability of the procedure. Therefore, in the current financial year, in the first place a scenario development methodology was constructed taking into account the requirements identified last year. Furthermore a practical work-frame was developed to support the activities related to the scenario development. This work-frame was applied to an example scenario to check its applicability and identify issues for further research. Secondly, scenario analysis method with regard to perturbation scenario has been studied. First of all, a survey of perturbation scenario discussed in different countries has been carried out and its assessment has been examined. Especially, in Japan, technical information has been classified in order to assess three scenarios, which are seismic activity, faulting and igneous activity. Then, on the basis of assumed occurrence pattern and influence pattern for each perturbation scenario, variant type that should be considered in this analysis has been identified, and the concept of treatment, modeling data and requirements have been clarified. As a result of these researches, a future direction for advanced scenario analysis on performance assessment has been indicated, as well as associated issues to be discussed have been clarified. (author)

  15. Including health economic analysis in pilot studies: lessons learned from a cost-utility analysis within the PROSPECTIV pilot study

    Directory of Open Access Journals (Sweden)

    Richéal M. Burns

    2017-07-01

    Full Text Available PurposeTo assess feasibility and health economic benefits and costs as part of a pilot study for a nurse-led, psychoeducational intervention (NPLI for prostate cancer in order to understand the potential for cost effectiveness as well as contribute to the design of a larger scale trial.MethodsMen with stable prostate cancer post-treatment were recruited from two cancer centres in the UK. Eighty-three men were randomised to the NLPI plus usual care or usual care alone (UCA (42 NLPI and 41 UCA; the NLPI plus usual care was delivered in the primary-care setting (the intervention and included an initial face-to-face consultation with a trained nurse, with follow-up tailored to individual needs. The study afforded the opportunity to undertake a short-term within pilot analysis. The primary outcome measure for the economic evaluation was quality of life, as measured by the EuroQol five dimensions questionnaire (EQ-5D (EQ-5D-5L instrument. Costs (£2014 assessed included health-service resource use, out-of-pocket expenses and losses from inability to undertake usual activities.ResultsTotal and incremental costs varied across the different scenarios assessed, with mean cost differences ranging from £173 to £346; incremental effect, as measured by the change in utility scores over the duration of follow-up, exhibited wide confidence intervals highlighting inconclusive effectiveness (95% CI: -0.0226; 0.0438. The cost per patient of delivery of the intervention would be reduced if rolled out to a larger patient cohort.ConclusionsThe NLPI is potentially cost saving depending on the scale of delivery; however, the results presented are not considered generalisable.

  16. Integrative Analysis of Gene Expression Data Including an Assessment of Pathway Enrichment for Predicting Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Pingzhao Hu

    2006-01-01

    Full Text Available Background: Microarray technology has been previously used to identify genes that are differentially expressed between tumour and normal samples in a single study, as well as in syntheses involving multiple studies. When integrating results from several Affymetrix microarray datasets, previous studies summarized probeset-level data, which may potentially lead to a loss of information available at the probe-level. In this paper, we present an approach for integrating results across studies while taking probe-level data into account. Additionally, we follow a new direction in the analysis of microarray expression data, namely to focus on the variation of expression phenotypes in predefined gene sets, such as pathways. This targeted approach can be helpful for revealing information that is not easily visible from the changes in the individual genes. Results: We used a recently developed method to integrate Affymetrix expression data across studies. The idea is based on a probe-level based test statistic developed for testing for differentially expressed genes in individual studies. We incorporated this test statistic into a classic random-effects model for integrating data across studies. Subsequently, we used a gene set enrichment test to evaluate the significance of enriched biological pathways in the differentially expressed genes identified from the integrative analysis. We compared statistical and biological significance of the prognostic gene expression signatures and pathways identified in the probe-level model (PLM with those in the probeset-level model (PSLM. Our integrative analysis of Affymetrix microarray data from 110 prostate cancer samples obtained from three studies reveals thousands of genes significantly correlated with tumour cell differentiation. The bioinformatics analysis, mapping these genes to the publicly available KEGG database, reveals evidence that tumour cell differentiation is significantly associated with many

  17. Examination of the regulatory frameworks applicable to biologic drugs (including stem cells and their progeny) in Europe, the U.S., and Australia: part I--a method of manual documentary analysis.

    Science.gov (United States)

    Ilic, Nina; Savic, Snezana; Siegel, Evan; Atkinson, Kerry; Tasic, Ljiljana

    2012-12-01

    Recent development of a wide range of regulatory standards applicable to production and use of tissues, cells, and other biologics (or biologicals), as advanced therapies, indicates considerable interest in the regulation of these products. The objective of this study was to analyze and compare high-tier documents within the Australian, European, and U.S. biologic drug regulatory environments using qualitative methodology. Cohort 1 of the selected 18 high-tier regulatory documents from the European Medicines Agency (EMA), the U.S. Food and Drug Administration (FDA), and the Therapeutic Goods Administration (TGA) regulatory frameworks were subject to a manual documentary analysis. These documents were consistent with the legal requirements for manufacturing and use of biologic drugs in humans and fall into six different categories. Manual analysis included a terminology search. The occurrence, frequency, and interchangeable use of different terms and phrases were recorded in the manual documentary analysis. Despite obvious differences, manual documentary analysis revealed certain consistency in use of terminology across analyzed frameworks. Phrase search frequencies have shown less uniformity than the search of terms. Overall, the EMA framework's documents referred to "medicinal products" and "marketing authorization(s)," the FDA documents discussed "drug(s)" or "biologic(s)," and the TGA documents referred to "biological(s)." Although high-tier documents often use different terminology they share concepts and themes. Documents originating from the same source have more conjunction in their terminology although they belong to different frameworks (i.e., Good Clinical Practice requirements based on the Declaration of Helsinki, 1964). Automated (software-based) documentary analysis should be obtained for the conceptual and relational analysis.

  18. Analysis of geodetic and legal documentation in the process of expropriation for roads. Krakow case study

    Science.gov (United States)

    Trembecka, Anna

    2013-06-01

    Amendment to the Act on special rules of preparation and implementation of investment in public roads resulted in an accelerated mode of acquisition of land for the development of roads. The decision to authorize the execution of road investment issued on its basis has several effects, i.e. determines the location of a road, approves surveying division, approves construction design and also results in acquisition of a real property by virtue of law by the State Treasury or local government unit, among others. The conducted study revealed that over 3 years, in this mode, the city of Krakow has acquired 31 hectares of land intended for the implementation of road investments. Compensation is determined in separate proceedings based on an appraisal study estimating property value, often at a distant time after the loss of land by the owner. One reason for the lengthy compensation proceedings is challenging the proposed amount of compensation, unregulated legal status of the property as well as imprecise legislation. It is important to properly develop geodetic and legal documentation which accompanies the application for issuance of the decision and is also used in compensation proceedings. Zmiana ustawy o szczególnych zasadach przygotowywania i realizacji inwestycji w zakresie dróg publicznych spowodowała przyspieszony tryb pozyskiwania gruntów przeznaczonych pod budowę dróg. Wydawana na jej podstawie decyzja o zezwoleniu na realizację inwestycji drogowej wywołuje szereg skutków, tj. m.in. ustala lokalizację drogi, zatwierdza podziały geodezyjne, zatwierdza projekt budowlany a także powoduje nabycie nieruchomości z mocy prawa, przez Skarb Państwa lub jednostki samorządu terytorialnego. Przeprowadzone badania wykazały iż w powyższym trybie miasto Kraków nabyło w okresie 3 lat ponad 31 ha gruntów przeznaczonych na realizację inwestycji drogowych. Odszkodowanie ustalane jest w drodze odrębnego postępowania w oparciu o operat szacunkowy okre

  19. Portfolio of prospective clinical trials including brachytherapy: an analysis of the ClinicalTrials.gov database

    International Nuclear Information System (INIS)

    Cihoric, Nikola; Tsikkinis, Alexandros; Miguelez, Cristina Gutierrez; Strnad, Vratislav; Soldatovic, Ivan; Ghadjar, Pirus; Jeremic, Branislav; Dal Pra, Alan; Aebersold, Daniel M.; Lössl, Kristina

    2016-01-01

    To evaluate the current status of prospective interventional clinical trials that includes brachytherapy (BT) procedures. The records of 175,538 (100 %) clinical trials registered at ClinicalTrials.gov were downloaded on September 2014 and a database was established. Trials using BT as an intervention were identified for further analyses. The selected trials were manually categorized according to indication(s), BT source, applied dose rate, primary sponsor type, location, protocol initiator and funding source. We analyzed trials across 8 available trial protocol elements registered within the database. In total 245 clinical trials were identified, 147 with BT as primary investigated treatment modality and 98 that included BT as an optional treatment component or as part of the standard treatment. Academic centers were the most frequent protocol initiators in trials where BT was the primary investigational treatment modality (p < 0.01). High dose rate (HDR) BT was the most frequently investigated type of BT dose rate (46.3 %) followed by low dose rate (LDR) (42.0 %). Prostate was the most frequently investigated tumor entity in trials with BT as the primary treatment modality (40.1 %) followed by breast cancer (17.0 %). BT was rarely the primary investigated treatment modality for cervical cancer (6.8 %). Most clinical trials using BT are predominantly in early phases, investigator-initiated and with low accrual numbers. Current investigational activities that include BT mainly focus on prostate and breast cancers. Important questions concerning the optimal usage of BT will not be answered in the near future. The online version of this article (doi:10.1186/s13014-016-0624-8) contains supplementary material, which is available to authorized users

  20. The BIM representation for documentation and historical-critical analysis of the Modernist heritage

    Directory of Open Access Journals (Sweden)

    Marcello Balzani

    2016-06-01

    Full Text Available BIM - Building Information Modeling applied to the historical-critical analysis and representation of the architectural heritage is becoming more and more an essential means for the understand- ing of design processes and changes over time, as well as a basic instrument for knowledge and as an aid for the design of conservation, mainte- nance, restoration and enhancement projects. The paper analyses BIM applications to the Indi- an and Brazilian modernist heritage, through the works of the greatest architects of the period, in- vestigated through a detailed methodology, also representative, which opens to further research- es and reinterpretations. 

  1. Stress analysis of fuel claddings with axial fins including creep effects

    International Nuclear Information System (INIS)

    Krieg, R.

    1977-01-01

    For LMFBR fuel claddings with axial fins the stress and strain fields are calculated which may be caused by internal pressure, differential thermal expansion and irradiation induced differential swelling. To provide an appropriate description of the cladding material it is assumed that the total strain is the sum of a linear elastic and a creep term, where the latter one includes the thermal as well as the irradiation induced creep. First the linear elastic problem is treated by a semi-analytical method leading to a bipotential equation for Airys' stress function. Solving this equation analytically means that the field equations valid within the cladding are satisfied exactly. By applying a combined point matching- least square-method the boundary conditions could be satisfied approximately such that in most cases the remaining error is within the uncertainty range of the loading conditions. Then the nonlinear problem which includes creep is approximated by a sequence of linear elastic solutions with time as parameter. The accumulated creep strain is treated here as an imposed strain field. To study the influence of different effects such as fin shape, temperature region, irradiation induced creep and swelling or internal pressure, a total of eleven cases with various parameter variations are investigated. The results are presented graphically in the following forms: stress and strain distributions over the cladding cross section for end of life conditions and boundary stresses and strains versus time. (Auth.)

  2. Dynamic Analysis of Thick Plates Including Deep Beams on Elastic Foundations Using Modified Vlasov Model

    Directory of Open Access Journals (Sweden)

    Korhan Ozgan

    2013-01-01

    Full Text Available Dynamic analysis of foundation plate-beam systems with transverse shear deformation is presented using modified Vlasov foundation model. Finite element formulation of the problem is derived by using an 8-node (PBQ8 finite element based on Mindlin plate theory for the plate and a 2-node Hughes element based on Timoshenko beam theory for the beam. Selective reduced integration technique is used to avoid shear locking problem for the evaluation of the stiffness matrices for both the elements. The effect of beam thickness, the aspect ratio of the plate and subsoil depth on the response of plate-beam-soil system is analyzed. Numerical examples show that the displacement, bending moments and shear forces are changed significantly by adding the beams.

  3. [Hypersexual disorder will not be included in the DSM V : a contextual analysis].

    Science.gov (United States)

    Toussaint, I; Pitchot, W

    2013-01-01

    Hypersexuality disorder has not been added to the list of psychiatric disorders for the Diagnostic and Statistical Manual of Mental Disorders (DSM) V, to be published in May 2013. The evolution of the concept of hypersexuality disorder and its series of different models call into question the controversial context within which its inclusion is considered for the DSM V. A brief contextual analysis makes clear that the creation of this concept follows moral norms and psychosocial values. The construction of hypersexuality disorder in terms of a diagnostic entity rests on the clash of social forces at play in the development process. This article lays the foundation to contemplate the manner in which entities for psychiatric disorders are constructed.

  4. Performance analysis of the MHD-steam combined cycle, including the influence of cost

    Science.gov (United States)

    Berry, G. F.; Dennis, C. B.

    1980-08-01

    A range of possible performance variables is explored in order to determine the sensitivity of a specific plant design to variation in key system parameters and, ultimately, to establish probable system performance limits. The comprehensive computer code that was developed analyzes and simulates an MHD plant for any number of different configurations, and holds constraints automatically while conducting either sensitivity studies or optimization. A summary of a sensitivity analysis conducted for a combined cycle, MHD steam power plant is presented. The influence of several of the more important system parameters were investigated and the results are presented in graphical form. The ANL cost algorithm is described and it is demonstrated that good agreement is obtained for the calculated cost of electricity.

  5. SAXS analysis of a soluble cytosolic NgBR construct including extracellular and transmembrane domains.

    Directory of Open Access Journals (Sweden)

    Joshua Holcomb

    Full Text Available The Nogo-B receptor (NgBR is involved in oncogenic Ras signaling through directly binding to farnesylated Ras. It recruits farnesylated Ras to the non-lipid-raft membrane for interaction with downstream effectors. However, the cytosolic domain of NgBR itself is only partially folded. The lack of several conserved secondary structural elements makes this domain unlikely to form a complete farnesyl binding pocket. We find that inclusion of the extracellular and transmembrane domains that contain additional conserved residues to the cytosolic region results in a well folded protein with a similar size and shape to the E.coli cis-isoprenyl transferase (UPPs. Small Angle X-ray Scattering (SAXS analysis reveals the radius of gyration (Rg of our NgBR construct to be 18.2 Å with a maximum particle dimension (Dmax of 61.0 Å. Ab initio shape modeling returns a globular molecular envelope with an estimated molecular weight of 23.0 kD closely correlated with the calculated molecular weight. Both Kratky plot and pair distribution function of NgBR scattering reveal a bell shaped peak which is characteristic of a single globularly folded protein. In addition, circular dichroism (CD analysis reveals that our construct has the secondary structure contents similar to the UPPs. However, this result does not agree with the currently accepted topological orientation of NgBR which might partition this construct into three separate domains. This discrepancy suggests another possible NgBR topology and lends insight into a potential molecular basis of how NgBR facilitates farnesylated Ras recruitment.

  6. Including Health in Environmental Assessments of Major Transport Infrastructure Projects: A Documentary Analysis.

    Science.gov (United States)

    Riley, Emily; Harris, Patrick; Kent, Jennifer; Sainsbury, Peter; Lane, Anna; Baum, Fran

    2018-05-10

    Transport policy and practice impacts health. Environmental Impact Assessments (EIAs) are regulated public policy mechanisms that can be used to consider the health impacts of major transport projects before they are approved. The way health is considered in these environmental assessments (EAs) is not well known. This research asked: How and to what extent was human health considered in EAs of four major transport projects in Australia. We developed a comprehensive coding framework to analyse the Environmental Impact Statements (EISs) of four transport infrastructure projects: three road and one light rail. The coding framework was designed to capture how health was directly and indirectly included. We found that health was partially considered in all four EISs. In the three New South Wales (NSW) projects, but not the one South Australian project, this was influenced by the requirements issued to proponents by the government which directed the content of the EIS. Health was assessed using human health risk assessment (HHRA). We found this to be narrow in focus and revealed a need for a broader social determinants of health approach, using multiple methods. The road assessments emphasised air quality and noise risks, concluding these were minimal or predicted to improve. The South Australian project was the only road project not to include health data explicitly. The light rail EIS considered the health benefits of the project whereas the others focused on risk. Only one project considered mental health, although in less detail than air quality or noise. Our findings suggest EIAs lag behind the known evidence linking transport infrastructure to health. If health is to be comprehensively included, a more complete model of health is required, as well as a shift away from health risk assessment as the main method used. This needs to be mandatory for all significant developments. We also found that considering health only at the EIA stage may be a significant

  7. Including Health in Environmental Assessments of Major Transport Infrastructure Projects: A Documentary Analysis

    Directory of Open Access Journals (Sweden)

    Emily Riley

    2018-02-01

    Full Text Available Background Transport policy and practice impacts health. Environmental Impact Assessments (EIAs are regulated public policy mechanisms that can be used to consider the health impacts of major transport projects before they are approved. The way health is considered in these environmental assessments (EAs is not well known. This research asked: How and to what extent was human health considered in EAs of four major transport projects in Australia. Methods We developed a comprehensive coding framework to analyse the Environmental Impact Statements (EISs of four transport infrastructure projects: three road and one light rail. The coding framework was designed to capture how health was directly and indirectly included. Results We found that health was partially considered in all four EISs. In the three New South Wales (NSW projects, but not the one South Australian project, this was influenced by the requirements issued to proponents by the government which directed the content of the EIS. Health was assessed using human health risk assessment (HHRA. We found this to be narrow in focus and revealed a need for a broader social determinants of health approach, using multiple methods. The road assessments emphasised air quality and noise risks, concluding these were minimal or predicted to improve. The South Australian project was the only road project not to include health data explicitly. The light rail EIS considered the health benefits of the project whereas the others focused on risk. Only one project considered mental health, although in less detail than air quality or noise. Conclusion Our findings suggest EIAs lag behind the known evidence linking transport infrastructure to health. If health is to be comprehensively included, a more complete model of health is required, as well as a shift away from health risk assessment as the main method used. This needs to be mandatory for all significant developments. We also found that considering health

  8. PTAC: a computer program for pressure-transient analysis, including the effects of cavitation. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Kot, C A; Youngdahl, C K

    1978-09-01

    PTAC was developed to predict pressure transients in nuclear-power-plant piping systems in which the possibility of cavitation must be considered. The program performs linear or nonlinear fluid-hammer calculations, using a fixed-grid method-of-characteristics solution procedure. In addition to pipe friction and elasticity, the program can treat a variety of flow components, pipe junctions, and boundary conditions, including arbitrary pressure sources and a sodium/water reaction. Essential features of transient cavitation are modeled by a modified column-separation technique. Comparisons of calculated results with available experimental data, for a simple piping arrangement, show good agreement and provide validation of the computational cavitation model. Calculations for a variety of piping networks, containing either liquid sodium or water, demonstrate the versatility of PTAC and clearly show that neglecting cavitation leads to erroneous predictions of pressure-time histories.

  9. Numerical analysis of trajectories and aberrations of a Wien filter including the effect of fringing fields

    Science.gov (United States)

    Kato, Makoto; Tsuno, Katsushige

    1990-12-01

    Trajectory equations of a stigmatic Wien filter including the effects of unmatched fringing fields are formulated, and an optimum shape with minimum geometrical aberrations is described. A low-aberration Wien filter is realized under the following conditions: (1) electric and magnetic fields satisfy the orthogonal relation even in the off-axial region, and (2) gap lengths between electrodes and magnetic poles are the same for achieving the balancing condition of electric and magnetic forces in fringing regions. The former condition can be realized by both fields with finite but the same hexapole components; this fact enables us to design a filter with simplified geometry that fulfills the latter condition simultaneously. It is shown that a large deflection of trajectories and resultant aberrations appear if the gap lengths are set to be different.

  10. Analysis of electronic models for solar cells including energy resolved defect densities

    Energy Technology Data Exchange (ETDEWEB)

    Glitzky, Annegret

    2010-07-01

    We introduce an electronic model for solar cells including energy resolved defect densities. The resulting drift-diffusion model corresponds to a generalized van Roosbroeck system with additional source terms coupled with ODEs containing space and energy as parameters for all defect densities. The system has to be considered in heterostructures and with mixed boundary conditions from device simulation. We give a weak formulation of the problem. If the boundary data and the sources are compatible with thermodynamic equilibrium the free energy along solutions decays monotonously. In other cases it may be increasing, but we estimate its growth. We establish boundedness and uniqueness results and prove the existence of a weak solution. This is done by considering a regularized problem, showing its solvability and the boundedness of its solutions independent of the regularization level. (orig.)

  11. Transient analysis of heat and mass transfer during heat treatment of wood including pressure equation

    Directory of Open Access Journals (Sweden)

    Younsi Ramdane

    2015-01-01

    Full Text Available In the present paper, three-dimensional equations for coupled heat and mass conservation equations for wood are solved to study the transient heat and mass transfer during high thermal treatment of wood. The model is based on Luikov’s approach, including pressure. The model equations are solved numerically by the commercial package FEMLfor the temperature and moisture content histories under different treatment conditions. The simulation of the proposed conjugate problem allows the assessment of the effect of the heat and mass transfer within wood. A parametric study was also carried out to determine the effects of several parameters such as initial moisture content and the sample thickness on the temperature, pressure and moisture content distributions within the samples during heat treatment.

  12. Nursing care systems and complex thought in nursing education: document analysis

    Directory of Open Access Journals (Sweden)

    Josilaine Porfírio da Silva

    Full Text Available The aim of this study was to analyse the inclusion of the subject Nursing Care Systems (NCS in nursing education. This study was based on qualitative desk research and it was conducted in a nursing programme in southern Brazil that offers an integrated curriculum with NCS as a cross-cutting theme. Data were collected from September to December 2012, by examining 15 planning and development workbooks on the cross-disciplinary modules of the programme. Analysis was divided into four stages: exploratory, selective, analytic and interpretive reading. The adopted theoretical framework was Complex Thought of Edgar Morin, according to the principles of relevant knowledge. Results were arranged into two categories: NCS as a crosscutting theme in nursing education: the context, the global and the multidimensional; and strategies for teaching, learning and assessment of NCS: the complex. The study contributes to the debate on the importance of teaching NCS as a crosscutting theme in nursing education.

  13. Tracking and Analysis Framework (TAF) model documentation and user`s guide

    Energy Technology Data Exchange (ETDEWEB)

    Bloyd, C.; Camp, J.; Conzelmann, G. [and others

    1996-12-01

    With passage of the 1990 Clean Air Act Amendments, the United States embarked on a policy for controlling acid deposition that has been estimated to cost at least $2 billion. Title IV of the Act created a major innovation in environmental regulation by introducing market-based incentives - specifically, by allowing electric utility companies to trade allowances to emit sulfur dioxide (SO{sub 2}). The National Acid Precipitation Assessment Program (NAPAP) has been tasked by Congress to assess what Senator Moynihan has termed this {open_quotes}grand experiment.{close_quotes} Such a comprehensive assessment of the economic and environmental effects of this legislation has been a major challenge. To help NAPAP face this challenge, the U.S. Department of Energy (DOE) has sponsored development of an integrated assessment model, known as the Tracking and Analysis Framework (TAF). This section summarizes TAF`s objectives and its overall design.

  14. Dynamic analysis of liquid storage tank including hydrodynamic interaction by boundary element method

    International Nuclear Information System (INIS)

    Hwang, I.T.; Ting, K.

    1987-01-01

    Dynamic response of liquid storage tanks considering the hydrodynamic interactions due to earthquake ground motion has been extensively studied. Several finite element procedures, such as Balendra et. al. (1982) and Haroun (1983), have been devoted to investigate the dynamic interaction between the deformable wall of the tank and the liquid. Further, if the geometry of the storage tank can not be described by axi-symmetric case, the tank wall and the fluid domain must be discretized by three dimensional finite elements to investigate the fluid-structure-interactions. Thus, the need of large computer memory and expense of vast computer time usually make this analysis impractical. To demonstrate the accuracy and reliability of the solution technique developed herein, the dynamic behavior of ground-supported, deformed, cylindrical tank with incompressible fluid conducted by Haroun (1983) are analyzed. Good correlations of hydrodynamic pressure distribution between the computed results with the referenced solutions are noted. The fluid compressibility significantly affects the hydrodynamic pressures of the liquid-tank-interactions and the work which is done on this discussion is still little attention. Thus, the influences of the compressibility of the liquid on the reponse of the liquid storage due to ground motion are then drawn. By the way, the complex-valued frequency response functions for hydrodynamic forces of Haroun's problem are also displayed. (orig./GL)

  15. Behavioral analysis of preterm neonates included in a tactile and kinesthetic stimulation program during hospitalization.

    Science.gov (United States)

    Ferreira, Andréia M; Bergamasco, Niélsy H P

    2010-01-01

    To evaluate the effect of tactile and kinesthetic stimulation on behavioral and clinical development in preterm neonates while still in the hospital. Thirty-two clinically stable preterm infants weighing kinesthetic stimulation (n=16). Data on the infants' clinical progress were collected from medical charts and behavioral evaluations by means of a series of weekly, eight-minute films recorded from the time of inclusion into the study until hospital discharge. There was a trend towards a shorter duration of hospital stay, increased daily weight gain and a predominance of self-regulated behavior (regular breathing, state of alertness, balanced tonus, a range of postures, coordinated movements, hand-to-face movement control, suction, grip, support) in infants in the SG. With respect to motor control, comparative analysis of postconceptional ages according to age-bracket (I - 31-33 weeks 6/7; II - 34-36 weeks 6/7; and III - 37-39 weeks 6/7) revealed balanced tonus and coordinated voluntary movements in all three periods, a longer time spent in a range of postures (age bracket I) or in flexion (age bracket II) and more regular breathing in age bracket I in the SG. In the hospital, tactile and kinesthetic stimulation was shown to have a positive effect, contributing towards adjustment and self-regulation of behavior in the preterm newborn infant. Article registered in the Australian New Zealand Clinical Trials Registry (ANZCTR) under the number ACTRN12610000133033.

  16. Constraints on inflation revisited. An analysis including the latest local measurement of the Hubble constant

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Rui-Yun [Northeastern University, Department of Physics, College of Sciences, Shenyang (China); Zhang, Xin [Northeastern University, Department of Physics, College of Sciences, Shenyang (China); Peking University, Center for High Energy Physics, Beijing (China)

    2017-12-15

    We revisit the constraints on inflation models by using the current cosmological observations involving the latest local measurement of the Hubble constant (H{sub 0} = 73.00 ± 1.75 km s{sup -1} Mpc{sup -1}). We constrain the primordial power spectra of both scalar and tensor perturbations with the observational data including the Planck 2015 CMB full data, the BICEP2 and Keck Array CMB B-mode data, the BAO data, and the direct measurement of H{sub 0}. In order to relieve the tension between the local determination of the Hubble constant and the other astrophysical observations, we consider the additional parameter N{sub eff} in the cosmological model. We find that, for the ΛCDM+r+N{sub eff} model, the scale invariance is only excluded at the 3.3σ level, and ΔN{sub eff} > 0 is favored at the 1.6σ level. Comparing the obtained 1σ and 2σ contours of (n{sub s},r) with the theoretical predictions of selected inflation models, we find that both the convex and the concave potentials are favored at 2σ level, the natural inflation model is excluded at more than 2σ level, the Starobinsky R{sup 2} inflation model is only favored at around 2σ level, and the spontaneously broken SUSY inflation model is now the most favored model. (orig.)

  17. Hepatotoxicity associated with statin use: analysis of the cases included in the Spanish Hepatotoxicity Registry

    Directory of Open Access Journals (Sweden)

    Emilia V. Perdices

    2014-04-01

    Full Text Available Objectives: The hepatotoxic potential of statins is controversial. The objectives of this study were to describe the relative frequency of hepatotoxicity caused by statins and the phenotypes found in Spain. Patients and methods: The incidence of hepatotoxicity attributed to statins in the Spanish Hepatotoxicity Registry (REH were studied and compared with those attributed to other drugs. Results: Between April 1994 and August 2012, the REH included a total of 858 cases of which 47 (5.5 % were attributed to statins. Of these, 16 were due to atorvastatin (34 %; 13 to simvastatin (27.7 %; 12 to fluvastatin (25.5 %; 4 to lovastatin (8.5 % and 2 to pravastatin (4.3 %. Statins represented approximately half of the cardiovascular group which occupied 3.er place (10 %, after anti-infectious agents (37 % and central nervous system drugs (14 %. The hepatocellular pattern was predominant, especially in the simvastatin group (85%, the cholestatic/mixed pattern was more frequent with fluvastatin (66 % and had a similar distribution to atorvastatin. Patients with statin-induced toxicity were older (62 years versus 53 years, p < 0.001 and more often demonstrated an autoimmune hepatitis phenotype (8.5 % versus 1.4 %, p < 0.003. Conclusions: Statins are not a common cause of hepatotoxicity in Spain. Atorvastatin is the statin involved in the greatest number of incidents. The liver injury pattern varies among the different statins. The hepatitis phenotype with autoimmune features appears to be a characteristic signature of statin-induced hepatotoxicity.

  18. An imprecise Dirichlet model for Bayesian analysis of failure data including right-censored observations

    International Nuclear Information System (INIS)

    Coolen, F.P.A.

    1997-01-01

    This paper is intended to make researchers in reliability theory aware of a recently introduced Bayesian model with imprecise prior distributions for statistical inference on failure data, that can also be considered as a robust Bayesian model. The model consists of a multinomial distribution with Dirichlet priors, making the approach basically nonparametric. New results for the model are presented, related to right-censored observations, where estimation based on this model is closely related to the product-limit estimator, which is an important statistical method to deal with reliability or survival data including right-censored observations. As for the product-limit estimator, the model considered in this paper aims at not using any information other than that provided by observed data, but our model fits into the robust Bayesian context which has the advantage that all inferences can be based on probabilities or expectations, or bounds for probabilities or expectations. The model uses a finite partition of the time-axis, and as such it is also related to life-tables

  19. Modeling and analysis of the affinity filtration process, including broth feeding, washing, and elution steps.

    Science.gov (United States)

    He, L Z; Dong, X Y; Sun, Y

    1998-01-01

    Affinity filtration is a developing protein purification technique that combines the high selectivity of affinity chromatography and the high processing speed of membrane filtration. In this work a lumped kinetic model was developed to describe the whole affinity filtration process, including broth feeding, contaminant washing, and elution steps. Affinity filtration experiments were conducted to evaluate the model using bovine serum albumin as a model protein and a highly substituted Blue Sepharose as an affinity adsorbent. The model with nonadjustable parameters agreed fairly to the experimental results. Thus, the performance of the affinity filtration in processing a crude broth containing contaminant proteins was analyzed by computer simulations using the lumped model. The simulation results show that there is an optimal protein loading for obtaining the maximum recovery yield of the desired protein with a constant purity at each operating condition. The concentration of a crude broth is beneficial in increasing the recovery yield of the desired protein. Using a constant amount of the affinity adsorbent, the recovery yield can be enhanced by decreasing the solution volume in the stirred tank due to the increase of the adsorbent weight fraction. It was found that the lumped kinetic model was simple and useful in analyzing the whole affinity filtration process.

  20. Risk Factor Analysis for AKI Including Laboratory Indicators: a Nationwide Multicenter Study of Hospitalized Patients

    Directory of Open Access Journals (Sweden)

    Sasa Nie

    2017-10-01

    Full Text Available Background/Aims: Risk factor studies for acute kidney injury (AKI in China are lacking, especially those regarding non-traditional risk factors, such as laboratory indicators. Methods: All adult patients admitted to 38 tertiary and 22 secondary hospitals in China in any one month between July and December 2014 were surveyed. AKI patients were screened according to the Kidney Disease: Improving Global Outcomes’ definition of AKI. Logistic regression was used to analyze the risk factors for AKI, and Cox regression was used to analyze the risk of in-hospital mortality for AKI patients; additionally, a propensity score analysis was used to reconfirm the risk factors among laboratory indicators for mortality. Results: The morbidity of AKI was 0.97%. Independent risk factors for AKI were advancing age, male gender, hypertension, and chronic kidney disease. All-cause mortality was 16.5%. The predictors of mortality in AKI patients were advancing age, tumor, higher uric acid level and increases in Acute Physiologic Assessment and Chronic Health Evaluation II and Sequential Organ Failure Assessment scores. The hazard ratio (HR for mortality with uric acid levels > 9.1 mg/dl compared with ≤ 5.2 mg/dl was 1.78 (95% CI: 1.23 to 2.58 for the AKI patients as a group, and was 1.73 (95% CI: 1.24 to 2.42 for a propensity score-matched set. Conclusion: In addition to traditional risk factors, uric acid level is an independent predictor of all-cause mortality after AKI.

  1. BWR transient analysis using neutronic / thermal hydraulic coupled codes including uncertainty quantification

    International Nuclear Information System (INIS)

    Hartmann, C.; Sanchez, V.; Tietsch, W.; Stieglitz, R.

    2012-01-01

    The KIT is involved in the development and qualification of best estimate methodologies for BWR transient analysis in cooperation with industrial partners. The goal is to establish the most advanced thermal hydraulic system codes coupled with 3D reactor dynamic codes to be able to perform a more realistic evaluation of the BWR behavior under accidental conditions. For this purpose a computational chain based on the lattice code (SCALE6/GenPMAXS), the coupled neutronic/thermal hydraulic code (TRACE/PARCS) as well as a Monte Carlo based uncertainty and sensitivity package (SUSA) has been established and applied to different kind of transients of a Boiling Water Reactor (BWR). This paper will describe the multidimensional models of the plant elaborated for TRACE and PARCS to perform the investigations mentioned before. For the uncertainty quantification of the coupled code TRACE/PARCS and specifically to take into account the influence of the kinetics parameters in such studies, the PARCS code has been extended to facilitate the change of model parameters in such a way that the SUSA package can be used in connection with TRACE/PARCS for the U and S studies. This approach will be presented in detail. The results obtained for a rod drop transient with TRACE/PARCS using the SUSA-methodology showed clearly the importance of some kinetic parameters on the transient progression demonstrating that the coupling of a best-estimate coupled codes with uncertainty and sensitivity tools is very promising and of great importance for the safety assessment of nuclear reactors. (authors)

  2. [Media and drugs: a documental analysis of the Brazilian writing media between 1999 and 2003].

    Science.gov (United States)

    Ronzani, Telmo Mota; Fernandes, Ameli Gabriele Batista; Gebara, Carla Ferreira de Paula; Oliveira, Samia Abreu; Scoralick, Natália Nunes; Lourenço, Lélio Moura

    2009-01-01

    This paper aims to analyze the kind of information published by the Brazilian 'written media' about drugs. It was examined articles about drugs in a national circulation magazine between 1999 and 2003, through an analysis of content. A total of 481 articles were found. 'Consumption' was the most appeared topic. The most quoted drugs were: cocaine (21%), marijuana (19%), alcoholic beverages (12%) and cigarettes (12%). This research also showed that 57% of the articles were related to cigarettes, its harmful effects, whereas alcohol had the same amount of articles showing it as a good or a bad substance for the human being and considered the most addictive drug (23%). On the other hand, cocaine was related to drug dealing (30%). In general, cocaine and marijuana were in focus in the media while alcohol and solvents had less prominence considering the epidemiologic data of use. We can notice that there is an incompatibility between the media focus and the profile of drug consumption in Brazil, that could influence the person's beliefs about certain substances and public politics about drugs in Brazil.

  3. Analysis of initial melanogenesis including tyrosinase transfer and melanosome differentiation through interrupted melanization by glutathione.

    Science.gov (United States)

    Imokawa, G

    1989-07-01

    complete formation of melanosome matrix structure and a lack of inhibition of cellular metabolisms including protein glycosylation.

  4. Characterization of Campylobacter phages including analysis of host range by selected Campylobacter Penner serotypes

    Directory of Open Access Journals (Sweden)

    Brown Stanley

    2007-10-01

    Full Text Available Abstract Background The predominant food borne pathogen in the western world today is Campylobacter. Campylobacter specific bacteriophages (phages have been proposed as an alternative agent for reducing the burden of Campylobacter in broilers. One concern in relation to phage biocontrol is the narrow host range often displayed by phages. To identify the potential of phages as a Campylobacter reducing agent we needed to determine their infectivity on a panel of isolates representing the Campylobacter strains found in broilers as well as humans. Results In this study, Campylobacter phages were isolated from the intestines of broilers and ducks and from abattoir sewage. Twelve phages were investigated to determine their ability to infect the Campylobacter Penner serotypes commonly present in Danish poultry and patients with campylobacteriosis. A total of 89% of the Campylobacter jejuni strains and 14% of the Campylobacter coli strains could be infected by at least one of the bacteriophages. The majority of the phages infected the most common serotypes in Danish broilers (O:1,44; O:2; O:4-complex, but showed limited ability to infect 21 of the less frequent Campylobacter serotypes. Pulse field gel electrophoresis (PFGE and restriction endonuclease analysis (REA were used to characterize the phage genomes. Three categories of bacteriophages were observed. I: a genome size of ~194 kb and refractory to digestion with HhaI; II: a genome size of ~140 kb and digestible by HhaI; and III: a genome size undeterminable in PFGE. The categorization of the phages correlated with the host range patterns displayed by the phages. Six phages were subjected to transmission electron microscopy (TEM. They all belonged to the family of Myoviridae. Conclusion We have characterized and identified the host range of 12 Danish Campylobacter phages. Due to their ability to infect the majority of the common serotypes in Denmark we suggest the phages can become an effective

  5. Characterization of Campylobacter phages including analysis of host range by selected Campylobacter Penner serotypes.

    Science.gov (United States)

    Hansen, Vinni Mona; Rosenquist, Hanne; Baggesen, Dorte Lau; Brown, Stanley; Christensen, Bjarke Bak

    2007-10-18

    The predominant food borne pathogen in the western world today is Campylobacter. Campylobacter specific bacteriophages (phages) have been proposed as an alternative agent for reducing the burden of Campylobacter in broilers. One concern in relation to phage biocontrol is the narrow host range often displayed by phages. To identify the potential of phages as a Campylobacter reducing agent we needed to determine their infectivity on a panel of isolates representing the Campylobacter strains found in broilers as well as humans. In this study, Campylobacter phages were isolated from the intestines of broilers and ducks and from abattoir sewage. Twelve phages were investigated to determine their ability to infect the Campylobacter Penner serotypes commonly present in Danish poultry and patients with campylobacteriosis. A total of 89% of the Campylobacter jejuni strains and 14% of the Campylobacter coli strains could be infected by at least one of the bacteriophages. The majority of the phages infected the most common serotypes in Danish broilers (O:1,44; O:2; O:4-complex), but showed limited ability to infect 21 of the less frequent Campylobacter serotypes. Pulse field gel electrophoresis (PFGE) and restriction endonuclease analysis (REA) were used to characterize the phage genomes. Three categories of bacteriophages were observed. I: a genome size of approximately 194 kb and refractory to digestion with HhaI; II: a genome size of approximately 140 kb and digestible by HhaI; and III: a genome size undeterminable in PFGE. The categorization of the phages correlated with the host range patterns displayed by the phages. Six phages were subjected to transmission electron microscopy (TEM). They all belonged to the family of Myoviridae. We have characterized and identified the host range of 12 Danish Campylobacter phages. Due to their ability to infect the majority of the common serotypes in Denmark we suggest the phages can become an effective agent in the effort to reduce

  6. Landsat time series analysis documents beaver migration into permafrost landscapes of arctic Alaska

    Science.gov (United States)

    Jones, B. M.; Tape, K. D.; Nitze, I.; Arp, C. D.; Grosse, G.; Zimmerman, C. E.

    2017-12-01

    Landscape-scale impacts of climate change in the Arctic include increases in growing season length, shrubby vegetation, winter river discharge, snowfall, summer and winter water temperatures, and decreases in river and lake ice thickness. Combined, these changes may have created conditions that are suitable for beaver colonization of low Arctic tundra regions. We developed a semi-automated workflow that analyzes Landsat imagery time series to determine the extent to which beavers may have colonized permafrost landscapes in arctic Alaska since 1999. We tested this approach on the Lower Noatak, Wulik, and Kivalina river watersheds in northwest Alaska and identified 83 locations representing potential beaver activity. Seventy locations indicated wetting trends and 13 indicated drying trends. Verification of each site using high-resolution satellite imagery showed that 80 % of the wetting locations represented beaver activity (damming and pond formation), 11 % were unrelated to beavers, and 9 % could not readily be distinguished as being beaver related or not. For the drying locations, 31 % represented beaver activity (pond drying due to dam abandonment), 62 % were unrelated to beavers, and 7 % were undetermined. Comparison of the beaver activity database with historic aerial photography from ca. 1950 and ca. 1980 indicates that beavers have recently colonized or recolonized riparian corridors in northwest Alaska. Remote sensing time series observations associated with the migration of beavers in permafrost landscapes in arctic Alaska include thermokarst lake expansion and drainage, thaw slump initiation, ice wedge degradation, thermokarst shore fen development, and possibly development of lake and river taliks. Additionally, beaver colonization in the Arctic may alter channel courses, thermal regimes, hyporheic flow, riparian vegetation, and winter ice regimes that could impact ecosystem structure and function in this region. In particular, the combination of beaver

  7. QA for test and analysis, documentation, recovery of data after test

    International Nuclear Information System (INIS)

    Zola, Maurizio

    2001-01-01

    Quality assurance for test and analysis implies the following qualification: the generation and maintenance of evidence to ensure that the equipment will operate on demand to meet the system performance requirements. (IEC 780-1984). This is presented through Standards and guidelines. The purpose of ISO 9000:2000, Quality management systems - Fundamentals and vocabulary is to establish a starting point for understanding the standards and defines the fundamental terms and definitions used in the ISO 9000 family. ISO 9001:2000, Quality management systems - Requirements, is the requirement standard to be used to assess ability to meet customer and applicable regulatory requirements and thereby address customer satisfaction. It is now the only standard in the ISO 9000 family against which third-party certification can be carried. ISO 9004:2000, Quality management systems - Guidelines for performance improvements provides guidance for continual improvement of your quality management system to benefit all parties through sustained customer satisfaction. ISO 9001:2000 specifies requirements for a quality management system for any organization that needs to demonstrate its ability to consistently provide product that meets customer and applicable regulatory requirements and aims to enhance customer satisfaction. ISO 9001:2000 is used if you are seeking to establish a management system that provides confidence in the conformance of your product to established or specified requirements. It is suggested that, beginning with ISO 9000:2000, you adopt ISO 9001:2000 to achieve a first level of performance. The practices described in ISO 9004:2000 may then be implemented to make your quality management system increasingly effective in achieving your own business goals. ISO 9004:2000 is used to extend the benefits obtained from ISO 9001:2000 to all parties that are interested. Using standards in this way will enable relation to other management systems

  8. Analysis of 30 Spinal Angiograms Falsely Reported as Normal in 18 Patients with Subsequently Documented Spinal Vascular Malformations.

    Science.gov (United States)

    Barreras, P; Heck, D; Greenberg, B; Wolinsky, J-P; Pardo, C A; Gailloud, P

    2017-09-01

    The early diagnosis of spinal vascular malformations suffers from the nonspecificity of their clinical and radiologic presentations. Spinal angiography requires a methodical approach to offer a high diagnostic yield. The prospect of false-negative studies is particularly distressing when addressing conditions with a narrow therapeutic window. The purpose of this study was to identify factors leading to missed findings or inadequate studies in patients with spinal vascular malformations. The clinical records, laboratory findings, and imaging features of 18 patients with spinal arteriovenous fistulas and at least 1 prior angiogram read as normal were reviewed. The clinical status was evaluated before and after treatment by using the Aminoff-Logue Disability Scale. Eighteen patients with 19 lesions underwent a total of 30 negative spinal angiograms. The lesions included 9 epidural arteriovenous fistulas, 8 dural arteriovenous fistulas, and 2 perimedullary arteriovenous fistulas. Seventeen patients underwent endovascular (11) or surgical (6) treatment, with a delay ranging between 1 week and 32 months; the Aminoff-Logue score improved in 13 (76.5%). The following factors were identified as the causes of the inadequate results: 1) lesion angiographically documented but not identified (55.6%); 2) region of interest not documented (29.6%); or 3) level investigated but injection technically inadequate (14.8%). All the angiograms falsely reported as normal were caused by correctible, operator-dependent factors. The nonrecognition of documented lesions was the most common cause of error. The potential for false-negative studies should be reduced by the adoption of rigorous technical and training standards and by second opinion reviews. © 2017 by American Journal of Neuroradiology.

  9. Documenting Your Inclusion Efforts.

    Science.gov (United States)

    Fritz, Marie F.; Miller, Maury

    This paper briefly addresses critical issues in documenting studies of the effectiveness of inclusive education for students with disabilities and includes a summary table of the existing literature and guidelines for problem solving about inclusion. The importance of sound methodology in documenting effects of inclusion and the dangers of value…

  10. Pre-hospital policies for the care of patients with acute coronary syndromes in India: A policy document analysis.

    Science.gov (United States)

    Patel, Amisha; Prabhakaran, Dorairaj; Berendsen, Mark; Mohanan, P P; Huffman, Mark D

    2017-04-01

    Ischemic heart disease is the leading cause of death in India. In high-income countries, pre-hospital systems of care have been developed to manage acute manifestations of ischemic heart disease, such as acute coronary syndrome (ACS). However, it is unknown whether guidelines, policies, regulations, or laws exist to guide pre-hospital ACS care in India. We undertook a nation-wide document analysis to address this gap in knowledge. From November 2014 to May 2016, we searched for publicly available emergency care guidelines and legislation addressing pre-hospital ACS care in all 29 Indian states and 7 Union Territories via Internet search and direct correspondence. We found two documents addressing pre-hospital ACS care. Though India has legislation mandating acute care for emergencies such as trauma, regulations or laws to guide pre-hospital ACS care are largely absent. Policy makers urgently need to develop comprehensive, multi-stakeholder policies for pre-hospital emergency cardiovascular care in India. Copyright © 2016. Published by Elsevier B.V.

  11. Supplement analysis for continued operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore. Volume 2: Comment response document

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The US Department of Energy (DOE), prepared a draft Supplement Analysis (SA) for Continued Operation of Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories, Livermore (SNL-L), in accordance with DOE`s requirements for implementation of the National Environmental Policy Act of 1969 (NEPA) (10 Code of Federal Regulations [CFR] Part 1021.314). It considers whether the Final Environmental Impact Statement and Environmental Impact Report for Continued Operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore (1992 EIS/EIR) should be supplement3ed, whether a new environmental impact statement (EIS) should be prepared, or no further NEPA documentation is required. The SA examines the current project and program plans and proposals for LLNL and SNL-L, operations to identify new or modified projects or operations or new information for the period from 1998 to 2002 that was not considered in the 1992 EIS/EIR. When such changes, modifications, and information are identified, they are examined to determine whether they could be considered substantial or significant in reference to the 1992 proposed action and the 1993 Record of Decision (ROD). DOE released the draft SA to the public to obtain stakeholder comments and to consider those comments in the preparation of the final SA. DOE distributed copies of the draft SA to those who were known to have an interest in LLNL or SNL-L activities in addition to those who requested a copy. In response to comments received, DOE prepared this Comment Response Document.

  12. Forensic Analysis of Blue Ball point Pen Inks on Questioned Documents by High Performance Thin Layer Chromatography Technique (HPTLC)

    International Nuclear Information System (INIS)

    Lee, L.C.; Siti Mariam Nunurung; Abdul Aziz Ishak

    2014-01-01

    Nowadays, crimes related to forged documents are increasing. Any erasure, addition or modification in the document content always involves the use of writing instrument such as ball point pens. Hence, there is an evident need to develop a fast and accurate ink analysis protocol to solve this problem. This study is aimed to determine the discrimination power of high performance thin layer chromatography (HPTLC) technique for analyzing a set of blue ball point pen inks. Ink samples deposited on paper were extracted using methanol and separated via a solvent mixture of ethyl acetate, methanol and distilled water (70: 35: 30, v/ v/ v). In this method, the discrimination power of 89.40 % was achieved, which confirm that the proposed method was able to differentiate a significant number of pen-pair samples. In addition, composition of blue pen inks was found to be homogeneous (RSD < 2.5 %) and the proposed method showed good repeatability and reproducibility (RSD < 3. 0%). As a conclusion, HPTLC is an effective tool to separate blue ball point pen inks. (author)

  13. Teaching of the Microbiological Analysis of Water Using a Computer Simulation Program That Includes Digitalized Color Images.

    Science.gov (United States)

    Fernandez, A.; And Others

    1992-01-01

    Describes microcomputer-based courseware designed for the simulation of the microbiological analysis of drinking water, including digitalized color images. The use of HyperCard is described and evaluation procedures are explained, including evaluation of the learning and of the class. The evaluation questionnaires are appended. (20 references)…

  14. Additional guidance for including nuclear safety equivalency in the Canister Storage Building and Cold Vacuum Drying Facility final safety analysis report

    International Nuclear Information System (INIS)

    Garvin, L.J.

    1997-01-01

    This document provides guidance for the production of safety analysis reports that must meet both DOE Order 5480.23 and STD 3009, and be in compliance with the DOE regulatory policy that imposes certain NRC requirements

  15. Additional guidance for including nuclear safety equivalency in the Canister Storage Building and Cold Vacuum Drying Facility final safety analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Garvin, L.J.

    1997-05-20

    This document provides guidance for the production of safety analysis reports that must meet both DOE Order 5480.23 and STD 3009, and be in compliance with the DOE regulatory policy that imposes certain NRC requirements.

  16. Technique for information retrieval using enhanced latent semantic analysis generating rank approximation matrix by factorizing the weighted morpheme-by-document matrix

    Science.gov (United States)

    Chew, Peter A; Bader, Brett W

    2012-10-16

    A technique for information retrieval includes parsing a corpus to identify a number of wordform instances within each document of the corpus. A weighted morpheme-by-document matrix is generated based at least in part on the number of wordform instances within each document of the corpus and based at least in part on a weighting function. The weighted morpheme-by-document matrix separately enumerates instances of stems and affixes. Additionally or alternatively, a term-by-term alignment matrix may be generated based at least in part on the number of wordform instances within each document of the corpus. At least one lower rank approximation matrix is generated by factorizing the weighted morpheme-by-document matrix and/or the term-by-term alignment matrix.

  17. Market Analysis and Consumer Impacts Source Document. Part II. Review of Motor Vehicle Market and Consumer Expenditures on Motor Vehicle Transportation

    Science.gov (United States)

    1980-12-01

    This source document on motor vehicle market analysis and consumer impacts consists of three parts. Part II consists of studies and review on: motor vehicle sales trends; motor vehicle fleet life and fleet composition; car buying patterns of the busi...

  18. The toxic effects of cigarette additives. Philip Morris' project mix reconsidered: an analysis of documents released through litigation.

    Directory of Open Access Journals (Sweden)

    Marcia S Wertz

    2011-12-01

    Full Text Available In 2009, the promulgation of US Food and Drug Administration (FDA tobacco regulation focused attention on cigarette flavor additives. The tobacco industry had prepared for this eventuality by initiating a research program focusing on additive toxicity. The objective of this study was to analyze Philip Morris' Project MIX as a case study of tobacco industry scientific research being positioned strategically to prevent anticipated tobacco control regulations.We analyzed previously secret tobacco industry documents to identify internal strategies for research on cigarette additives and reanalyzed tobacco industry peer-reviewed published results of this research. We focused on the key group of studies conducted by Phillip Morris in a coordinated effort known as "Project MIX." Documents showed that Project MIX subsumed the study of various combinations of 333 cigarette additives. In addition to multiple internal reports, this work also led to four peer-reviewed publications (published in 2001. These papers concluded that there was no evidence of substantial toxicity attributable to the cigarette additives studied. Internal documents revealed post hoc changes in analytical protocols after initial statistical findings indicated an additive-associated increase in cigarette toxicity as well as increased total particulate matter (TPM concentrations in additive-modified cigarette smoke. By expressing the data adjusted by TPM concentration, the published papers obscured this underlying toxicity and particulate increase. The animal toxicology results were based on a small number of rats in each experiment, raising the possibility that the failure to detect statistically significant changes in the end points was due to underpowering the experiments rather than lack of a real effect.The case study of Project MIX shows tobacco industry scientific research on the use of cigarette additives cannot be taken at face value. The results demonstrate that toxins in

  19. The toxic effects of cigarette additives. Philip Morris' project mix reconsidered: an analysis of documents released through litigation.

    Science.gov (United States)

    Wertz, Marcia S; Kyriss, Thomas; Paranjape, Suman; Glantz, Stanton A

    2011-12-01

    In 2009, the promulgation of US Food and Drug Administration (FDA) tobacco regulation focused attention on cigarette flavor additives. The tobacco industry had prepared for this eventuality by initiating a research program focusing on additive toxicity. The objective of this study was to analyze Philip Morris' Project MIX as a case study of tobacco industry scientific research being positioned strategically to prevent anticipated tobacco control regulations. We analyzed previously secret tobacco industry documents to identify internal strategies for research on cigarette additives and reanalyzed tobacco industry peer-reviewed published results of this research. We focused on the key group of studies conducted by Phillip Morris in a coordinated effort known as "Project MIX." Documents showed that Project MIX subsumed the study of various combinations of 333 cigarette additives. In addition to multiple internal reports, this work also led to four peer-reviewed publications (published in 2001). These papers concluded that there was no evidence of substantial toxicity attributable to the cigarette additives studied. Internal documents revealed post hoc changes in analytical protocols after initial statistical findings indicated an additive-associated increase in cigarette toxicity as well as increased total particulate matter (TPM) concentrations in additive-modified cigarette smoke. By expressing the data adjusted by TPM concentration, the published papers obscured this underlying toxicity and particulate increase. The animal toxicology results were based on a small number of rats in each experiment, raising the possibility that the failure to detect statistically significant changes in the end points was due to underpowering the experiments rather than lack of a real effect. The case study of Project MIX shows tobacco industry scientific research on the use of cigarette additives cannot be taken at face value. The results demonstrate that toxins in cigarette smoke

  20. The Toxic Effects of Cigarette Additives. Philip Morris' Project Mix Reconsidered: An Analysis of Documents Released through Litigation

    Science.gov (United States)

    Wertz, Marcia S.; Kyriss, Thomas; Paranjape, Suman; Glantz, Stanton A.

    2011-01-01

    Background In 2009, the promulgation of US Food and Drug Administration (FDA) tobacco regulation focused attention on cigarette flavor additives. The tobacco industry had prepared for this eventuality by initiating a research program focusing on additive toxicity. The objective of this study was to analyze Philip Morris' Project MIX as a case study of tobacco industry scientific research being positioned strategically to prevent anticipated tobacco control regulations. Methods and Findings We analyzed previously secret tobacco industry documents to identify internal strategies for research on cigarette additives and reanalyzed tobacco industry peer-reviewed published results of this research. We focused on the key group of studies conducted by Phillip Morris in a coordinated effort known as “Project MIX.” Documents showed that Project MIX subsumed the study of various combinations of 333 cigarette additives. In addition to multiple internal reports, this work also led to four peer-reviewed publications (published in 2001). These papers concluded that there was no evidence of substantial toxicity attributable to the cigarette additives studied. Internal documents revealed post hoc changes in analytical protocols after initial statistical findings indicated an additive-associated increase in cigarette toxicity as well as increased total particulate matter (TPM) concentrations in additive-modified cigarette smoke. By expressing the data adjusted by TPM concentration, the published papers obscured this underlying toxicity and particulate increase. The animal toxicology results were based on a small number of rats in each experiment, raising the possibility that the failure to detect statistically significant changes in the end points was due to underpowering the experiments rather than lack of a real effect. Conclusion The case study of Project MIX shows tobacco industry scientific research on the use of cigarette additives cannot be taken at face value. The

  1. ExactPack Documentation

    Energy Technology Data Exchange (ETDEWEB)

    Singleton, Robert Jr. [Los Alamos National Laboratory; Israel, Daniel M. [Los Alamos National Laboratory; Doebling, Scott William [Los Alamos National Laboratory; Woods, Charles Nathan [Los Alamos National Laboratory; Kaul, Ann [Los Alamos National Laboratory; Walter, John William Jr [Los Alamos National Laboratory; Rogers, Michael Lloyd [Los Alamos National Laboratory

    2016-05-09

    For code verification, one compares the code output against known exact solutions. There are many standard test problems used in this capacity, such as the Noh and Sedov problems. ExactPack is a utility that integrates many of these exact solution codes into a common API (application program interface), and can be used as a stand-alone code or as a python package. ExactPack consists of python driver scripts that access a library of exact solutions written in Fortran or Python. The spatial profiles of the relevant physical quantities, such as the density, fluid velocity, sound speed, or internal energy, are returned at a time specified by the user. The solution profiles can be viewed and examined by a command line interface or a graphical user interface, and a number of analysis tools and unit tests are also provided. We have documented the physics of each problem in the solution library, and provided complete documentation on how to extend the library to include additional exact solutions. ExactPack’s code architecture makes it easy to extend the solution-code library to include additional exact solutions in a robust, reliable, and maintainable manner.

  2. CMS DOCUMENTATION

    CERN Multimedia

    CMS TALKS AT MAJOR MEETINGS The agenda and talks from major CMS meetings can now be electronically accessed from the iCMS Web site. The following items can be found on: http://cms.cern.ch/iCMS/ General - CMS Weeks (Collaboration Meetings), CMS Weeks Agendas The talks presented at the Plenary Sessions. LHC Symposiums Management - CB - MB - FB - FMC Agendas and minutes are accessible to CMS members through their AFS account (ZH). However some linked documents are restricted to the Board Members. FB documents are only accessible to FB members. LHCC The talks presented at the ‘CMS Meetings with LHCC Referees’ are available on request from the PM or MB Country Representative. Annual Reviews The talks presented at the 2006 Annual reviews are posted.   CMS DOCUMENTS It is considered useful to establish information on the first employment of CMS doctoral students upon completion of their theses. Therefore it is requested that Ph.D students inform the CMS Secretariat a...

  3. CMS DOCUMENTATION

    CERN Multimedia

    CMS TALKS AT MAJOR MEETINGS The agenda and talks from major CMS meetings can now be electronically accessed from the iCMS Web site. The following items can be found on: http://cms.cern.ch/iCMS/ General - CMS Weeks (Collaboration Meetings), CMS Weeks Agendas The talks presented at the Plenary Sessions. LHC Symposiums Management - CB - MB - FB - FMC Agendas and minutes are accessible to CMS members through their AFS account (ZH). However some linked documents are restricted to the Board Members. FB documents are only accessible to FB members. LHCC The talks presented at the ‘CMS Meetings with LHCC Referees’ are available on request from the PM or MB Country Representative. Annual Reviews The talks presented at the 2006 Annual reviews are posted. CMS DOCUMENTS It is considered useful to establish information on the first employment of CMS doctoral students upon completion of their theses. Therefore it is requested that Ph.D students inform the CMS Secretariat about the natu...

  4. CMS DOCUMENTATION

    CERN Multimedia

    CMS TALKS AT MAJOR MEETINGS The agenda and talks from major CMS meetings can now be electronically accessed from the iCMS Web site. The following items can be found on: http://cms.cern.ch/iCMS/ General - CMS Weeks (Collaboration Meetings), CMS Weeks Agendas The talks presented at the Plenary Sessions. LHC Symposiums Management - CB - MB - FB - FMC Agendas and minutes are accessible to CMS members through their AFS account (ZH). However some linked documents are restricted to the Board Members. FB documents are only accessible to FB members. LHCC The talks presented at the ‘CMS Meetings with LHCC Referees’ are available on request from the PM or MB Country Representative. Annual Reviews The talks presented at the 2006 Annual reviews are posted. CMS DOCUMENTS It is considered useful to establish information on the first employment of CMS doctoral students upon completion of their theses. Therefore it is requested that Ph.D students inform the CMS Secretariat about the natur...

  5. CMS DOCUMENTATION

    CERN Multimedia

    CMS TALKS AT MAJOR MEETINGS The agenda and talks from major CMS meetings can now be electronically accessed from the iCMS Web site. The following items can be found on: http://cms.cern.ch/iCMS/ General - CMS Weeks (Collaboration Meetings), CMS Weeks Agendas The talks presented at the Plenary Sessions. LHC Symposiums Management - CB - MB - FB - FMC Agendas and minutes are accessible to CMS members through their AFS account (ZH). However some linked documents are restricted to the Board Members. FB documents are only accessible to FB members. LHCC The talks presented at the ‘CMS Meetings with LHCC Referees’ are available on request from the PM or MB Country Representative. Annual Reviews The talks presented at the 2006 Annual reviews are posted. CMS DOCUMENTS It is considered useful to establish information on the first employment of CMS doctoral students upon completion of their theses. Therefore it is requested that Ph.D students inform the CMS Secretariat about the na...

  6. CMS DOCUMENTATION

    CERN Multimedia

    CMS TALKS AT MAJOR MEETINGS The agenda and talks from major CMS meetings can now be electronically accessed from the iCMS Web site. The following items can be found on: http://cms.cern.ch/iCMS/ Management- CMS Weeks (Collaboration Meetings), CMS Weeks Agendas The talks presented at the Plenary Sessions. Management - CB - MB - FB Agendas and minutes are accessible to CMS members through their AFS account (ZH). However some linked documents are restricted to the Board Members. FB documents are only accessible to FB members. LHCC The talks presented at the ‘CMS Meetings with LHCC Referees’ are available on request from the PM or MB Country Representative. Annual Reviews The talks presented at the 2007 Annual reviews are posted. CMS DOCUMENTS It is considered useful to establish information on the first employment of CMS doctoral students upon completion of their theses. Therefore it is requested that Ph.D students inform the CMS Secretariat about the nature of em¬pl...

  7. CMS DOCUMENTATION

    CERN Multimedia

    CMS TALKS AT MAJOR MEETINGS The agenda and talks from major CMS meetings can now be electronically accessed from the iCMS Web site. The following items can be found on: http://cms.cern.ch/iCMS/ Management- CMS Weeks (Collaboration Meetings), CMS Weeks Agendas The talks presented at the Plenary Sessions. Management - CB - MB - FB Agendas and minutes are accessible to CMS members through their AFS account (ZH). However some linked documents are restricted to the Board Members. FB documents are only accessible to FB members. LHCC The talks presented at the ‘CMS Meetings with LHCC Referees’ are available on request from the PM or MB Country Representative. Annual Reviews The talks presented at the 2007 Annual reviews are posted. CMS DOCUMENTS It is considered useful to establish information on the first employment of CMS doctoral students upon completion of their theses. Therefore it is requested that Ph.D students inform the CMS Secretariat about the nature of employment and ...

  8. Micro-spectrochemical analysis of document paper and gel inks by laser ablation inductively coupled plasma mass spectrometry and laser induced breakdown spectroscopy

    International Nuclear Information System (INIS)

    Trejos, Tatiana; Flores, Alejandra; Almirall, Jose R.

    2010-01-01

    Current methods used in document examinations are not suitable to associate or discriminate between sources of paper and gel inks with a high degree of certainty. Nearly non-destructive, laser-based methods using laser induced breakdown spectroscopy (LIBS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) were used to improve the forensic comparisons of gel inks, ballpoint inks and document papers based on similarities in elemental composition. Some of the advantages of these laser-based methods include minimum sample consumption/destruction, high sensitivity, high selectivity and excellent discrimination between samples from different origins. Figures of merit are reported including limits of detection, precision, homogeneity at a micro-scale and linear dynamic range. The variation of the elemental composition in paper was studied within a single sheet, between pages from the same ream, between papers produced by the same plant at different time intervals and between seventeen paper sources produced by ten different plants. The results show that elemental analysis of paper by LIBS and LA-ICP-MS provides excellent discrimination (> 98%) between different sources. Batches manufactured at weekly and monthly intervals in the same mill were also differentiated. The ink of more than 200 black pens was analyzed to determine the variation of the chemical composition of the ink within a single pen, between pens from the same package and between brands of gel inks and ballpoint inks. Homogeneity studies show smaller variation of elemental compositions within a single source than between different sources (i.e. brands and types). It was possible to discriminate between pen markings from different brands and between pen markings from the same brand but different model. Discrimination of ∼ 96-99% was achieved for sets that otherwise would remain inseparable by conventional methods. The results show that elemental analysis, using either LA-ICP-MS or

  9. Micro-spectrochemical analysis of document paper and gel inks by laser ablation inductively coupled plasma mass spectrometry and laser induced breakdown spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Trejos, Tatiana, E-mail: trejost@fiu.edu [Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199 (United States); International Forensic Research Institute (IFRI), Florida International University, Miami, FL 3319 (United States); Flores, Alejandra, E-mail: aflor017@fiu.edu [Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199 (United States); Almirall, Jose R., E-mail: almirall@fiu.edu [Department of Chemistry and Biochemistry, Florida International University, Miami, FL 33199 (United States); International Forensic Research Institute (IFRI), Florida International University, Miami, FL 3319 (United States)

    2010-11-15

    Current methods used in document examinations are not suitable to associate or discriminate between sources of paper and gel inks with a high degree of certainty. Nearly non-destructive, laser-based methods using laser induced breakdown spectroscopy (LIBS) and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) were used to improve the forensic comparisons of gel inks, ballpoint inks and document papers based on similarities in elemental composition. Some of the advantages of these laser-based methods include minimum sample consumption/destruction, high sensitivity, high selectivity and excellent discrimination between samples from different origins. Figures of merit are reported including limits of detection, precision, homogeneity at a micro-scale and linear dynamic range. The variation of the elemental composition in paper was studied within a single sheet, between pages from the same ream, between papers produced by the same plant at different time intervals and between seventeen paper sources produced by ten different plants. The results show that elemental analysis of paper by LIBS and LA-ICP-MS provides excellent discrimination (> 98%) between different sources. Batches manufactured at weekly and monthly intervals in the same mill were also differentiated. The ink of more than 200 black pens was analyzed to determine the variation of the chemical composition of the ink within a single pen, between pens from the same package and between brands of gel inks and ballpoint inks. Homogeneity studies show smaller variation of elemental compositions within a single source than between different sources (i.e. brands and types). It was possible to discriminate between pen markings from different brands and between pen markings from the same brand but different model. Discrimination of {approx} 96-99% was achieved for sets that otherwise would remain inseparable by conventional methods. The results show that elemental analysis, using either LA

  10. Ca analysis: An Excel based program for the analysis of intracellular calcium transients including multiple, simultaneous regression analysis☆

    Science.gov (United States)

    Greensmith, David J.

    2014-01-01

    Here I present an Excel based program for the analysis of intracellular Ca transients recorded using fluorescent indicators. The program can perform all the necessary steps which convert recorded raw voltage changes into meaningful physiological information. The program performs two fundamental processes. (1) It can prepare the raw signal by several methods. (2) It can then be used to analyze the prepared data to provide information such as absolute intracellular Ca levels. Also, the rates of change of Ca can be measured using multiple, simultaneous regression analysis. I demonstrate that this program performs equally well as commercially available software, but has numerous advantages, namely creating a simplified, self-contained analysis workflow. PMID:24125908

  11. Documentation and analysis of a global CO{sub 2} model developed by Peng et al. (1983)

    Energy Technology Data Exchange (ETDEWEB)

    Jager, H.I.; Peng, T.H.; King, A.W.; Sale, M.J.

    1990-07-01

    A global carbon model, the Peng `83 model, has been standardized according to protocols developed for an intermodel comparison. The first part of this document describes the model as they received it, and the second part describes a standardized version of the model, which has been parameterized according to the protocols described. Model performance was evaluated according to defined criteria and a sensitivity analysis of the model was conducted to identify the most important parameters. The standardized model was supplemented with a calibration routine to define reasonable combinations of initial conditions. This improved the ability of the model to hold an initial equilibrium state. Sensitivity analysis showed a shift in parameter importances with time. The initial conditions were of greatest importance for the length of these simulations, but declined in longer simulations. With the initial pCO{sub 2} excluded from the sensitivity analysis, ocean surface area (used to extrapolate results) was second in importance. While the CO{sub 2} exchange rate were initially most important, the model projections of atmospheric CO{sub 2} soon became more sensitive to the alkalinity of the ocean.

  12. Evaluation of Publicly Available Documents to Trace Chiropractic Technique Systems That Advocate Radiography for Subluxation Analysis: A Proposed Genealogy

    Science.gov (United States)

    Young, Kenneth J.

    2014-01-01

    Objective The purpose of this study was to evaluate publicly available information of chiropractic technique systems that advocate radiography for subluxation detection to identify links between chiropractic technique systems and to describe claims made of the health effects of the osseous misalignment component of the chiropractic subluxation and radiographic paradigms. Methods The Internet and publicly available documents were searched for information representing chiropractic technique systems that advocate radiography for subluxation detection. Key phrases including chiropractic, x-ray, radiography, and technique were identified from a Google search between April 2013 and March 2014. Phrases in Web sites and public documents were examined for any information about origins and potential links between these techniques, including the type of connection to BJ Palmer, who was the first chiropractor to advocate radiography for subluxation detection. Quotes were gathered to identify claims of health effects from osseous misalignment (subluxation) and paradigms of radiography. Techniques were grouped by region of the spine and how they could be traced back to B.J Palmer. A genealogy model and summary table of information on each technique were created. Patterns in year of origination and radiographic paradigms were noted, and percentages were calculated on elements of the techniques’ characteristics in comparison to the entire group. Results Twenty-three techniques were identified on the Internet: 6 full spine, 17 upper cervical, and 2 techniques generating other lineage. Most of the upper cervical techniques (14/16) traced their origins to a time when the Palmer School was teaching upper cervical technique, and all the full spine techniques (6/6) originated before or after this phase. All the technique systems’ documents attributed broad health effects to their methods. Many (21/23) of the techniques used spinal realignment on radiographs as one of their outcome

  13. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-02-18

    This document describes the qualitative evaluation of frequency and consequences for double shell tank (DST) and single shell tank (SST) representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant SSCs and/or TSRS were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support of the Tank Farms Documented Safety Analysis (DSA) and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  14. FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    KRIPPS, L.J.

    2005-03-03

    This document describes the qualitative evaluation of frequency and consequences for DST and SST representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant structures, systems and components (SSCs) and/or technical safety requirements (TSRs) were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support WP-13033, Tank Farms Documented Safety Analysis (DSA), and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

  15. Time-motion analysis of clinical nursing documentation during implementation of an electronic operating room management system for ophthalmic surgery.

    Science.gov (United States)

    Read-Brown, Sarah; Sanders, David S; Brown, Anna S; Yackel, Thomas R; Choi, Dongseok; Tu, Daniel C; Chiang, Michael F

    2013-01-01

    Efficiency and quality of documentation are critical in surgical settings because operating rooms are a major source of revenue, and because adverse events may have enormous consequences. Electronic health records (EHRs) have potential to impact surgical volume, quality, and documentation time. Ophthalmology is an ideal domain to examine these issues because procedures are high-throughput and demand efficient documentation. This time-motion study examines nursing documentation during implementation of an EHR operating room management system in an ophthalmology department. Key findings are: (1) EHR nursing documentation time was significantly worse during early implementation, but improved to a level near but slightly worse than paper baseline, (2) Mean documentation time varied significantly among nurses during early implementation, and (3) There was no decrease in operating room turnover time or surgical volume after implementation. These findings have important implications for ambulatory surgery departments planning EHR implementation, and for research in system design.

  16. Analysis of image acquisition, post-processing and documentation in adolescents with spine injuries. Comparison before and after referral to a university hospital

    International Nuclear Information System (INIS)

    Lemburg, S.P.; Roggenland, D.; Nicolas, V.; Heyer, C.M.

    2012-01-01

    Purpose: Systematic evaluation of imaging situation and standards in acute spinal injuries of adolescents. Materials and Methods: Retrospective analysis of imaging studies of transferred adolescents with spinal injuries and survey of transferring hospitals (TH) with respect to the availability of modalities and radiological expertise and post-processing and documentation of CT studies were performed. Repetitions of imaging studies and cumulative effective dose (CED) were noted. Results: 33 of 43 patients (77 %) treated in our hospital (MA 17.2 years, 52 % male) and 25 of 32 TH (78 %) were evaluated. 24-hr availability of conventional radiography and CT was present in 96 % and 92 % of TH, whereas MRI was available in only 36 %. In 64 % of TH, imaging expertise was guaranteed by an on-staff radiologist. During off-hours radiological service was provided on an on-call basis in 56 % of TH. Neuroradiologic and pediatric radiology expertise was not available in 44 % and 60 % of TH, respectively. CT imaging including post-processing and documentation matched our standards in 36 % and 32 % of cases. The repetition rate of CT studies was 39 % (CED 116.08 mSv). Conclusion: With frequent CT repetitions, two-thirds of re-examined patients revealed a different clinical estimation of trauma severity and insufficient CT quality as possible causes for re-examination. A standardization of initial clinical evaluation and CT imaging could possibly reduce the need for repeat examinations. (orig.)

  17. 41 CFR 102-80.105 - What information must be included in an equivalent level of safety analysis?

    Science.gov (United States)

    2010-07-01

    ... engineer. The analysis should include a narrative discussion of the features of the building structure... and location of fuel items, space layout, building construction, openings and ventilation, suppression capability, detection time, occupant notification, occupant reaction time, occupant mobility, and means of...

  18. Summit documents

    International Nuclear Information System (INIS)

    2003-01-01

    This document gathers three declarations about the non-proliferation of massive destruction weapons, made by the G8 organization participants during their last summit held in Evian (France): declaration about the enforcement and respect of the non-proliferation measures implemented by the IAEA and by the conventions for chemical and biological weapons; declaration about the protection of radioactive sources against diversion (regulatory control, inventory, control of sources export etc..); warranty about the security of radioactive sources (G8 approach, sustain of the IAEA action, sustain to the most vulnerable states, control mechanisms, political commitment of states, implementation of the recommendations of the international conference about the security and safety of radiation sources, held in Vienna (Austria) on March 2003. (J.S.)

  19. The development of methods of analysis of documents on the basis of the methods of Raman spectroscopy and fluorescence analysis

    Science.gov (United States)

    Gorshkova, Kseniia O.; Tumkin, Ilya I.; Kirillova, Elizaveta O.; Panov, Maxim S.; Kochemirovsky, Vladimir A.

    2017-05-01

    The investigation of natural aging of writing inks printed on paper using Raman spectroscopy was performed. Based on the obtained dependencies of the Raman peak intensities ratios on the exposure time, the dye degradation model was proposed. It was suggested that there are several competing bond breaking and bond forming reactions corresponding to the characteristic vibration frequencies of the dye molecule that simultaneously occur during ink aging process. Also we propose a methodology based on the study of the optical properties of paper, particularly changes in the fluorescence of optical brighteners included in its composition as well as the paper reflectivity using spectrophotometric methods. These results can be implemented to develop the novel and promising method of criminology.

  20. Final safety analysis report for the Galileo mission: Volume 3 (Book 2), Nuclear risk analysis document: Appendices: Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-25

    It is the purpose of the NRAD to provide an analysis of the range of potential consequences of accidents which have been identified that are associated with the launching and deployment of the Galileo mission spacecraft. The specific consequences analyzed are those associated with the possible release of radioactive material (fuel) of the Radioisotope Thermoelectric Generators (RTGs). They are in terms of radiation doses to people and areas of deposition of radioactive material. These consequence analyses can be used in several ways. One way is to identify the potential range of consequences which might have to be dealt with if there were to be an accident with a release of fuel, so as to assure that, given such an accident, the health and safety of the public will be reasonably protected. Another use of the information, in conjunction with accident and release probabilities, is to estimate the risks associated with the mission. That is, most space launches occur without incident. Given an accident, the most probable result relative to the RTGs is complete containment of the radioactive material. Only a small fraction of accidents might result in a release of fuel and subsequent radiological consequences. The combination of probability with consequence is risk, which can be compared to other human and societal risks to assure that no undue risks are implied by undertaking the mission. Book 2 contains eight appendices.

  1. Different forms of assessment and documentation in Swedish preschools

    Directory of Open Access Journals (Sweden)

    Ann-Christine Vallberg-Roth

    2012-12-01

    Full Text Available Abstract: The aim is to describe and discuss documentation and assessment practices in Swedish preschools from a didaktik perspective. What different forms of documentation and assessment are found in the preschools? Preschools in both urban and rural municipalities are included in the selection.  Document and textual analysis are used. A varied multi-documentation emerge. The multi-documentation at each preschool expose that preschool teachers seem to switch between different forms of documentation and assessment, including summative, formative and other assessments. The concept of transformative assessment may capture the different assessments interwoven in the multi-documentation. Transformative assessment is a concept focusing on reshaping and interplaying assessments that are intertwined in the registration and complex documentation at different levels and directions.

  2. Corrective Action Decision Document for Corrective Action Unit 168: Areas 25 and 26 Contaminated Materials and Waste Dumps, Nevada Test Site, Nevada: Revision 0, Including Record of Technical Change No. 1

    Energy Technology Data Exchange (ETDEWEB)

    U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

    2003-08-08

    This Corrective Action Decision Document identifies and rationalizes the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office's selection of recommended corrective action alternatives (CAAs) to facilitate the closure of Corrective Action Unit (CAU)168: Areas 25 and 26 Contaminated Materials and Waste Dumps, Nevada Test Site (NTS), Nevada, under the Federal Facility Agreement and Consent Order. Located in Areas 25 and 26 at the NTS in Nevada, CAU 168 is comprised of twelve Corrective Action Sites (CASs). Review of data collected during the corrective action investigation, as well as consideration of current and future operations in Areas 25 and 26 of the NTS, led the way to the development of three CAAs for consideration: Alternative 1 - No Further Action; Alternative 2 - Clean Closure; and Alternative 3 - Close in Place with Administrative Controls. As a result of this evaluation, a combination of all three CAAs is recommended for this CAU. Alternative 1 was the preferred CAA for three CASs, Alternative 2 was the preferred CAA for six CASs (and nearly all of one other CAS), and Alternative 3 was the preferred CAA for two CASs (and a portion of one other CAS) to complete the closure at the CAU 168 sites. These alternatives were judged to meet all requirements for the technical components evaluated as well as all applicable state and federal regulations for closure of the sites and elimination of potential future exposure pathways to the contaminated soils at CAU 168.

  3. CNEA's quality system documentation

    International Nuclear Information System (INIS)

    Mazzini, M.M.; Garonis, O.H.

    1998-01-01

    Full text: To obtain an effective and coherent documentation system suitable for CNEA's Quality Management Program, we decided to organize the CNEA's quality documentation with : a- Level 1. Quality manual. b- Level 2. Procedures. c-Level 3. Qualities plans. d- Level 4: Instructions. e- Level 5. Records and other documents. The objective of this work is to present a standardization of the documentation of the CNEA's quality system of facilities, laboratories, services, and R and D activities. Considering the diversity of criteria and formats for elaboration the documentation by different departments, and since ultimately each of them generally includes the same quality management policy, we proposed the elaboration of a system in order to improve the documentation, avoiding unnecessary time wasting and costs. This will aloud each sector to focus on their specific documentation. The quality manuals of the atomic centers fulfill the rule 3.6.1 of the Nuclear Regulatory Authority, and the Safety Series 50-C/SG-Q of the International Atomic Energy Agency. They are designed by groups of competent and highly trained people of different departments. The normative procedures are elaborated with the same methodology as the quality manuals. The quality plans which describe the organizational structure of working group and the appropriate documentation, will asses the quality manuals of facilities, laboratories, services, and research and development activities of atomic centers. The responsibilities for approval of the normative documentation are assigned to the management in charge of the administration of economic and human resources in order to fulfill the institutional objectives. Another improvement aimed to eliminate unnecessary invaluable processes is the inclusion of all quality system's normative documentation in the CNEA intranet. (author) [es

  4. CMS DOCUMENTATION

    CERN Multimedia

    CMS TALKS AT MAJOR MEETINGS The agenda and talks from major CMS meetings can now be electronically accessed from the ICMS Web site. The following items can be found on: http://cms.cern.ch/iCMS Management – CMS Weeks (Collaboration Meetings), CMS Weeks Agendas The talks presented at the Plenary Sessions. Management – CB – MB – FB Agendas and minutes are accessible to CMS members through Indico. LHCC The talks presented at the ‘CMS Meetings with LHCC Referees’ are available on request from the PM or MB Country Representative. Annual Reviews The talks presented at the 2008 Annual Reviews are posted in Indico. CMS DOCUMENTS It is considered useful to establish information on the first employment of CMS doctoral student upon completion of their theses.  Therefore it is requested that Ph.D students inform the CMS Secretariat about the nature of employment and name of their first employer. The Notes, Conference Reports and Theses published si...

  5. Ethical issues in umbilical cord blood banking: a comparative analysis of documents from national and international institutions.

    Science.gov (United States)

    Petrini, Carlo

    2013-04-01

    The issues of collection, storage, and use of cord blood (CB) stem cells have been addressed extensively in national and international guidelines, policies, and regulations. Many of these documents are not binding, but are nonetheless accorded considerable respect on account of the authority of the issuing organizations. Most discussion has to date focused on two topics: informed consent for collection, banking, and use and the debate between those who favor public storage for altruistic purposes and those who advocate private storage for autologous use. There is generally agreement or consensus in the guidelines that public storage for allogeneic transplants is preferable and that private storage should be discouraged. Given the consensus in national and international guidance on these two issues, it is time for other ethical issues to be examined in greater detail. These include additional uses of CB samples, for example, for research or for the production of blood-derived drugs, and the economic implications arising from the extensive international network for the exchange of CB for transplantation. © 2012 American Association of Blood Banks.

  6. Recent Progress on Labfit: a Multispectrum Analysis Program for Fitting Lineshapes Including the Htp Model and Temperature Dependence

    Science.gov (United States)

    Cich, Matthew J.; Guillaume, Alexandre; Drouin, Brian; Benner, D. Chris

    2017-06-01

    Multispectrum analysis can be a challenge for a variety of reasons. It can be computationally intensive to fit a proper line shape model especially for high resolution experimental data. Band-wide analyses including many transitions along with interactions, across many pressures and temperatures are essential to accurately model, for example, atmospherically relevant systems. Labfit is a fast multispectrum analysis program originally developed by D. Chris Benner with a text-based interface. More recently at JPL a graphical user interface was developed with the goal of increasing the ease of use but also the number of potential users. The HTP lineshape model has been added to Labfit keeping it up-to-date with community standards. Recent analyses using labfit will be shown to demonstrate its ability to competently handle large experimental datasets, including high order lineshape effects, that are otherwise unmanageable.

  7. Nontargeted nuclear magnetic resonance (NMR) analysis to detect hazardous substances including methanol in unrecorded alcohol from Novosibirsk, Russia

    OpenAIRE

    Hausler, Thomas; Okaru,  Alex O.; Neufeld, Maria; Rehm, Jürgen; Kuballa, Thomas; Luy, Burkhard; Lachenmeier, Dirk W.

    2016-01-01

    Nuclear magnetic resonance (NMR) spectroscopy was applied to the analysis of alcoholic products in the context of health and safety control. A total of 86 samples of unrecorded alcohol were collected in Novosibirsk and nearby cities in Russia. Sampling was based on interviews with alcohol dependent patients, and unrecorded alcohol thus defined included illegally or informally produced alcoholic products (e.g., counterfeit or home-made alcoholic beverages) or surrogate alcohol in the form of c...

  8. Detection of Organic Constituents Including Chloromethylpropene in the Analyses of the ROCKNEST Drift by Sample Analysis at Mars (SAM)

    Science.gov (United States)

    Eigenbrode, J. L.; Glavin, D.; Coll, P.; Summons, R. E.; Mahaffy, P.; Archer, D.; Brunner, A.; Conrad, P.; Freissinet, C.; Martin, M.; hide

    2013-01-01

    key challenge in assessing the habitability of martian environments is the detection of organic matter - a requirement of all life as we know it. The Curiosity rover, which landed on August 6, 2012 in Gale Crater of Mars, includes the Sample Analysis at Mars (SAM) instrument suite capable of in situ analysis of gaseous organic components thermally evolved from sediment samples collected, sieved, and delivered by the MSL rover. On Sol 94, SAM received its first solid sample: scooped sediment from Rocknest that was sieved to analysis was performed. This blank served 1) to clean the analytical instrument of SAMinternal materials that accumulated in the gas processing system since integration into the rover, and 2) to characterize the background signatures of SAM. Both the blank and the Rocknest samples showed the presence of hydrocarbon components.

  9. Manned space flight nuclear system safety. Volume 3: Reactor system preliminary nuclear safety analysis. Part 3: Nuclear Safety Analysis Document (NSAD)

    Science.gov (United States)

    1972-01-01

    Nuclear safety analysis as applied to a space base mission is presented. The nuclear safety analysis document summarizes the mission and the credible accidents/events which may lead to nuclear hazards to the general public. The radiological effects and associated consequences of the hazards are discussed in detail. The probability of occurrence is combined with the potential number of individuals exposed to or above guideline values to provide a measure of accident and total mission risk. The overall mission risk has been determined to be low with the potential exposure to or above 25 rem limited to less than 4 individuals per every 1000 missions performed. No radiological risk to the general public occurs during the prelaunch phase at KSC. The most significant risks occur from prolonged exposure to reactor debris following land impact generally associated with the disposal phase of the mission where fission product inventories can be high.

  10. Omega documentation

    Energy Technology Data Exchange (ETDEWEB)

    Howerton, R.J.; Dye, R.E.; Giles, P.C.; Kimlinger, J.R.; Perkins, S.T.; Plechaty, E.F.

    1983-08-01

    OMEGA is a CRAY I computer program that controls nine codes used by LLNL Physical Data Group for: 1) updating the libraries of evaluated data maintained by the group (UPDATE); 2) calculating average values of energy deposited in secondary particles and residual nuclei (ENDEP); 3) checking the libraries for internal consistency, especially for energy conservation (GAMCHK); 4) producing listings, indexes and plots of the library data (UTILITY); 5) producing calculational constants such as group averaged cross sections and transfer matrices for diffusion and Sn transport codes (CLYDE); 6) producing and updating standard files of the calculational constants used by LLNL Sn and diffusion transport codes (NDFL); 7) producing calculational constants for Monte Carlo transport codes that use group-averaged cross sections and continuous energy for particles (CTART); 8) producing and updating standard files used by the LLNL Monte Carlo transport codes (TRTL); and 9) producing standard files used by the LANL pointwise Monte Carlo transport code MCNP (MCPOINT). The first four of these functions and codes deal with the libraries of evaluated data and the last five with various aspects of producing calculational constants for use by transport codes. In 1970 a series, called PD memos, of internal and informal memoranda was begun. These were intended to be circulated among the group for comment and then to provide documentation for later reference whenever questions arose about the subject matter of the memos. They have served this purpose and now will be drawn upon as source material for this more comprehensive report that deals with most of the matters covered in those memos.

  11. Omega documentation

    International Nuclear Information System (INIS)

    Howerton, R.J.; Dye, R.E.; Giles, P.C.; Kimlinger, J.R.; Perkins, S.T.; Plechaty, E.F.

    1983-08-01

    OMEGA is a CRAY I computer program that controls nine codes used by LLNL Physical Data Group for: 1) updating the libraries of evaluated data maintained by the group (UPDATE); 2) calculating average values of energy deposited in secondary particles and residual nuclei (ENDEP); 3) checking the libraries for internal consistency, especially for energy conservation (GAMCHK); 4) producing listings, indexes and plots of the library data (UTILITY); 5) producing calculational constants such as group averaged cross sections and transfer matrices for diffusion and Sn transport codes (CLYDE); 6) producing and updating standard files of the calculational constants used by LLNL Sn and diffusion transport codes (NDFL); 7) producing calculational constants for Monte Carlo transport codes that use group-averaged cross sections and continuous energy for particles (CTART); 8) producing and updating standard files used by the LLNL Monte Carlo transport codes (TRTL); and 9) producing standard files used by the LANL pointwise Monte Carlo transport code MCNP (MCPOINT). The first four of these functions and codes deal with the libraries of evaluated data and the last five with various aspects of producing calculational constants for use by transport codes. In 1970 a series, called PD memos, of internal and informal memoranda was begun. These were intended to be circulated among the group for comment and then to provide documentation for later reference whenever questions arose about the subject matter of the memos. They have served this purpose and now will be drawn upon as source material for this more comprehensive report that deals with most of the matters covered in those memos

  12. Safety and fitness electronic records (SAFER) system : logical architecture document : working draft

    Science.gov (United States)

    1997-01-31

    This Logical Architecture Document includes the products developed during the functional analysis of the Safety and Fitness Electronic Records (SAFER) System. This document, along with the companion Operational Concept and Physical Architecture Docum...

  13. Physical urticaria: Review on classification, triggers and management with special focus on prevalence including a meta-analysis.

    Science.gov (United States)

    Trevisonno, Jordan; Balram, Bhairavi; Netchiporouk, Elena; Ben-Shoshan, Moshe

    2015-08-01

    Physical urticaria (PU) is a subset of chronic urticaria (CU) induced by physical stimuli. To date, there is no consensus in the literature on the prevalence of PU among patients with CU. Our objective was to review the clinical presentation, diagnosis and management of PU and to estimate the prevalence of PU in CU patients. We performed a narrative review of PU and conducted a systemic review and meta-analysis to determine the pooled estimates of the prevalence of PU among patients with CU in the literature up to September 2014. We searched four databases (PubMed, Ovid MEDLINE and Web of Science) of published work for which full text was available in English or French. Studies were eligible if they measured the prevalence of PU in adults or children with CU worldwide and ineligible if CU cases were not differentiated from total urticaria cases. Meta-analysis was conducted using Stata, version 12.0 (StataCorp, College Station, TX). In addition, the quality and validity of the articles included in the meta-analysis was assessed. Ten studies were included in our meta-analysis. Sample sizes ranged from 202 to 4157 patients. The pooled prevalence estimate of PU including and excluding cholinergic forms among all cases of CU were 13.1% (95% CI: 12.5, 13.6) and 14.9% (95% CI: 14.3, 15.7), respectively. Our results must be viewed with circumspection because of the small number of eligible articles and heterogeneity among studies. Even so, the results suggest that PU is an important subset of CU and that physicians should be aware of this important condition in order to manage patients appropriately.

  14. Document turn-over analysis to determine need of NPP construction in build-up structures of reinforced concrete

    International Nuclear Information System (INIS)

    Vojpe, D.K.; Lyubavin, V.K.

    1986-01-01

    Document turn-over to determine used of NPP construction in build-up structures of reinforced concrete is carried out. Ways of improving determination of needs of NPP construction board in the mentioned structures are pointed out

  15. Transportation System Requirements Document

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    This Transportation System Requirements Document (Trans-SRD) describes the functions to be performed by and the technical requirements for the Transportation System to transport spent nuclear fuel (SNF) and high-level radioactive waste (HLW) from Purchaser and Producer sites to a Civilian Radioactive Waste Management System (CRWMS) site, and between CRWMS sites. The purpose of this document is to define the system-level requirements for Transportation consistent with the CRWMS Requirement Document (CRD). These requirements include design and operations requirements to the extent they impact on the development of the physical segments of Transportation. The document also presents an overall description of Transportation, its functions, its segments, and the requirements allocated to the segments and the system-level interfaces with Transportation. The interface identification and description are published in the CRWMS Interface Specification.

  16. Tocilizumab use in pregnancy: Analysis of a global safety database including data from clinical trials and post-marketing data.

    Science.gov (United States)

    Hoeltzenbein, Maria; Beck, Evelin; Rajwanshi, Richa; Gøtestam Skorpen, Carina; Berber, Erhan; Schaefer, Christof; Østensen, Monika

    2016-10-01

    Analyze the cumulative evidence for pregnancy outcomes after maternal exposure to tocilizumab, an anti-interleukin-6-receptor monoclonal antibody used for the treatment of rheumatoid arthritis and juvenile idiopathic arthritis. At present, published experience on tocilizumab use during pregnancy is very limited. We have analyzed all pregnancy-related reports documented in the Roche Global Safety Database until December 31, 2014 (n = 501). After exclusion of ongoing pregnancies, duplicates, and cases retrieved from the literature, 399 women were found to have been exposed to tocilizumab shortly before or during pregnancy, with pregnancy outcomes being reported in 288 pregnancies (72.2%). Of these 288 pregnancies, 180 were prospectively reported resulting in 109 live births (60.6%), 39 spontaneous abortions (21.7%), 31 elective terminations of pregnancy (17.2%), and 1 stillbirth. The rate of malformations was 4.5%. Co-medications included methotrexate in 21.1% of the prospectively ascertained cases. Compared to the general population, an increased rate of preterm birth (31.2%) was observed. Retrospectively reported pregnancies (n = 108) resulted in 55 live births (50.9%), 31 spontaneous abortions (28.7%), and 22 elective terminations (20.4%). Three infants/fetuses with congenital anomalies were reported in this group. No increased risks for adverse pregnancy outcomes were observed after paternal exposure in 13 pregnancies with known outcome. No indication for a substantially increased malformation risk was observed. Considering the limitations of global safety databases, the data do not yet prove safety, but provide information for physicians and patients to make informed decisions. This is particularly important after inadvertent exposure to tocilizumab, shortly before or during early pregnancy. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. ELECTRICAL POWER SYSTEM DESCRIPTION DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    M. Maniyar

    2004-06-22

    The purpose of this revision of the System Description Document (SDD) is to establish requirements that drive the design of the electrical power system and their bases to allow the design effort to proceed to License Application. This SDD is a living document that will be revised at strategic points as the design matures over time. This SDD identifies the requirements and describes the system design as they exist at this time, with emphasis on those attributes of the design provided to meet the requirements. This SDD has been developed to be an engineering tool for design control. Accordingly, the primary audience are design engineers. This type of SDD leads and follows the design process. It leads the design process with regard to the flow down of upper tier requirements onto the system. Knowledge of these requirements is essential to performing the design process. This SDD follows the design with regard to the description of the system. The description provided in the SDD is a reflection of the results of the design process to date. Functional and operational requirements applicable to this system are obtained from ''Project Functional and Operational Requirements'' (F&OR) (Siddoway, 2003). Other requirements to support the design process have been taken from higher level requirements documents such as ''Project Design Criteria Document'' (PDC) (Doraswamy 2004), the fire hazards analyses, and the preclosure safety analysis. The above mentioned low-level documents address ''Project Requirements Document'' (PRD) (Canori and Leitner 2003) requirements. This SDD includes several appendices with supporting information. Appendix B lists key system charts, diagrams, drawings, and lists; and Appendix C is a list of system procedures.

  18. A meta-analysis including dose-response relationship between night shift work and the risk of colorectal cancer.

    Science.gov (United States)

    Wang, Xiao; Ji, Alin; Zhu, Yi; Liang, Zhen; Wu, Jian; Li, Shiqi; Meng, Shuai; Zheng, Xiangyi; Xie, Liping

    2015-09-22

    A meta-analysis was conducted to quantitatively evaluate the correlation between night shift work and the risk of colorectal cancer. We searched for publications up to March 2015 using PubMed, Web of Science, Cochrane Library, EMBASE and the Chinese National Knowledge Infrastructure databases, and the references of the retrieved articles and relevant reviews were also checked. OR and 95% CI were used to assess the degree of the correlation between night shift work and risk of colorectal cancer via fixed- or random-effect models. A dose-response meta-analysis was performed as well. The pooled OR estimates of the included studies illustrated that night shift work was correlated with an increased risk of colorectal cancer (OR = 1.318, 95% CI 1.121-1.551). No evidence of publication bias was detected. In the dose-response analysis, the rate of colorectal cancer increased by 11% for every 5 years increased in night shift work (OR = 1.11, 95% CI 1.03-1.20). In conclusion, this meta-analysis indicated that night shift work was associated with an increased risk of colorectal cancer. Further researches should be conducted to confirm our findings and clarify the potential biological mechanisms.

  19. Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites

    Directory of Open Access Journals (Sweden)

    Hofmann Alan F

    2010-05-01

    Full Text Available Abstract Background Bile salts are the major end-metabolites of cholesterol and are also important in lipid and protein digestion and in influencing the intestinal microflora. We greatly extend prior surveys of bile salt diversity in both reptiles and mammals, including analysis of 8,000 year old human coprolites and coprolites from the extinct Shasta ground sloth (Nothrotherium shastense. Results While there is significant variation of bile salts across species, bile salt profiles are generally stable within families and often within orders of reptiles and mammals, and do not directly correlate with differences in diet. The variation of bile salts generally accords with current molecular phylogenies of reptiles and mammals, including more recent groupings of squamate reptiles. For mammals, the most unusual finding was that the Paenungulates (elephants, manatees, and the rock hyrax have a very different bile salt profile from the Rufous sengi and South American aardvark, two other mammals classified with Paenungulates in the cohort Afrotheria in molecular phylogenies. Analyses of the approximately 8,000 year old human coprolites yielded a bile salt profile very similar to that found in modern human feces. Analysis of the Shasta ground sloth coprolites (approximately 12,000 years old showed the predominant presence of glycine-conjugated bile acids, similar to analyses of bile and feces of living sloths, in addition to a complex mixture of plant sterols and stanols expected from an herbivorous diet. Conclusions The bile salt synthetic pathway has become longer and more complex throughout vertebrate evolution, with some bile salt modifications only found within single groups such as marsupials. Analysis of the evolution of bile salt structures in different species provides a potentially rich model system for the evolution of a complex biochemical pathway in vertebrates. Our results also demonstrate the stability of bile salts in coprolites

  20. Evolutionary diversity of bile salts in reptiles and mammals, including analysis of ancient human and extinct giant ground sloth coprolites

    Science.gov (United States)

    2010-01-01

    Background Bile salts are the major end-metabolites of cholesterol and are also important in lipid and protein digestion and in influencing the intestinal microflora. We greatly extend prior surveys of bile salt diversity in both reptiles and mammals, including analysis of 8,000 year old human coprolites and coprolites from the extinct Shasta ground sloth (Nothrotherium shastense). Results While there is significant variation of bile salts across species, bile salt profiles are generally stable within families and often within orders of reptiles and mammals, and do not directly correlate with differences in diet. The variation of bile salts generally accords with current molecular phylogenies of reptiles and mammals, including more recent groupings of squamate reptiles. For mammals, the most unusual finding was that the Paenungulates (elephants, manatees, and the rock hyrax) have a very different bile salt profile from the Rufous sengi and South American aardvark, two other mammals classified with Paenungulates in the cohort Afrotheria in molecular phylogenies. Analyses of the approximately 8,000 year old human coprolites yielded a bile salt profile very similar to that found in modern human feces. Analysis of the Shasta ground sloth coprolites (approximately 12,000 years old) showed the predominant presence of glycine-conjugated bile acids, similar to analyses of bile and feces of living sloths, in addition to a complex mixture of plant sterols and stanols expected from an herbivorous diet. Conclusions The bile salt synthetic pathway has become longer and more complex throughout vertebrate evolution, with some bile salt modifications only found within single groups such as marsupials. Analysis of the evolution of bile salt structures in different species provides a potentially rich model system for the evolution of a complex biochemical pathway in vertebrates. Our results also demonstrate the stability of bile salts in coprolites preserved in arid climates

  1. Training and knowledge development for use of software for safety analysis including ANSYS. Simulation of thermal-hydraulic benchmarks

    International Nuclear Information System (INIS)

    2016-01-01

    Comparison of both axial mean and rms velocities of the current analysis with the benchmark submissions and experimental results were consistent, showing that the LES transient model of ANSYS CFX is applicable to the problem of T-junction mixing and to predict the location of thermal fatigue from temperature differences. Study of ICEM CFD (Computational Fluid Dynamics) should be able to provide more tools for a finer hexahedral mesh of the T-junction leading to better results. A video of the flow in time obtained from CFD Post is included with this report to help with visualizing the results of the temperature variation along the pipe

  2. International Journal of Occupational Medicine and Environmental Health in world documentation services: the SCOPUS based analysis of citation.

    Science.gov (United States)

    Przyłuska, Jolanta

    2006-01-01

    A high classification of scientific journals in the ranking of international transfer of knowledge is reflected by other researchers' citations. The International Journal of Occupational Medicine and Environmental Health (IJOMEH) is an international professional quarterly focused on such areas as occupational medicine, toxicology and environmental health edited in Poland. IJOMEH, published in English, is indexed in numerous world information services (MEDLINE, EMBASE, EBSCO, SCOPUS). This paper presents the contribution of IJOMEH publications to the world circulation of scientific information based on the citation analysis. The analysis, grounded on the SCOPUS database, assessed the frequency of citations in the years 1996-2005. Journals in which they have been cited were retrieved and their list is also included.

  3. Areva - 2014 Reference document

    International Nuclear Information System (INIS)

    2015-01-01

    Areva supplies high added-value products and services to support the operation of the global nuclear fleet. The company is present throughout the entire nuclear cycle, from uranium mining to used fuel recycling, including nuclear reactor design and operating services. Areva is recognized by utilities around the world for its expertise, its skills in cutting-edge technologies and its dedication to the highest level of safety. Areva's 44,000 employees are helping build tomorrow's energy model: supplying ever safer, cleaner and more economical energy to the greatest number of people. This Reference Document contains information on Areva's objectives, prospects and development strategies. It contains estimates of the markets, market shares and competitive position of Areva. Contents: 1 - Person responsible; 2 - Statutory auditors; 3 - Selected financial information; 4 - Risk factors; 5 - Information about the issuer; 6 - Business overview; 7 - Organizational structure; 8 - Property, plant and equipment; 9 - Analysis of and comments on the group's financial position and performance; 10 - Capital resources; 11 - Research and development programs, patents and licenses; 12 - Trend information; 13 - Profit forecasts; 14 - Administrative, management and supervisory bodies and senior management; 15 - Compensation and benefits; 16 - Functioning of administrative, management and supervisory bodies and senior management; 17 - Employees; 18 - Principal shareholders; 19 - Transactions with related parties; 20 - Financial information concerning assets, financial positions and financial performance; 21 - Additional information; 22 - Major contracts; 23 - Third party information, statements by experts and declarations of interest; 24 - Documents on display; 25 - information on holdings; appendix: Report of the Chairman of the Board of Directors on governance, internal control procedures and risk management, Statutory Auditors' report, Corporate social

  4. Methylenetetrahydrofolate Reductase Polymorphisms and Risk of Acute Lymphoblastic Leukemia-Evidence from an updated meta-analysis including 35 studies

    Directory of Open Access Journals (Sweden)

    Wang Haigang

    2012-09-01

    Full Text Available Abstract Background 5,10-methylenetetrahydrofolate reductase (MTHFR variants, C677T and A1298C, have been reported to be associated with decreased risk of acute lymphoblastic leukemia (ALL. However, results derived from individually underpowered studies are conflicting. We carried out an updated meta-analysis on the association between MTHFR polymorphisms and ALL risk. Methods Relevant publications were searched through PUBMED and EMBASE databases. The associations between MTHFR C677T and A1298C polymorphisms and the risk of ALL were evaluated by odds ratios (ORs. The heterogeneity and publication bias were estimated. Meta-regression analysis was performed to evaluate the potential sources of heterogeneity. Results C677T polymorphism was associated with a reduced risk of ALL (allele contrast: ORRE = 0.91, 95% CI: 0.83-0.99. Subgroup analysis showed MTHFR C677T variant was associated with decreased susceptibility to ALL in children and Caucasians. Meta-regression showed the logOR for the association between T allele and ALL increased as sex ratio (M/F in the case group increased (P = 0.01. Regarding A1298C polymorphism, no significant association was observed (allele contrast: ORRE = 1.01, 95% CI: 0.91-1.11. There was no publication bias for C677T or A1298C polymorphism. Conclusions The present meta-analysis suggests that the C677T polymorphism, not A1298C, in MTHFR gene is associated with a decreased risk of ALL, particularly among children and Caucasians subjects. Our findings suggest that the influence of the C677T polymorphism on ALL susceptibility is modified by sex ratio in cases (M/F. Since folate intake may be a possible confounding factor, including this factor in future prospective studies is warranted. Further meta-analysis studies should be at least stratified for folate levels and gender to give more powerful and informative results.

  5. Methylenetetrahydrofolate Reductase Polymorphisms and Risk of Acute Lymphoblastic Leukemia-Evidence from an updated meta-analysis including 35 studies

    Science.gov (United States)

    2012-01-01

    Background 5,10-methylenetetrahydrofolate reductase (MTHFR) variants, C677T and A1298C, have been reported to be associated with decreased risk of acute lymphoblastic leukemia (ALL). However, results derived from individually underpowered studies are conflicting. We carried out an updated meta-analysis on the association between MTHFR polymorphisms and ALL risk. Methods Relevant publications were searched through PUBMED and EMBASE databases. The associations between MTHFR C677T and A1298C polymorphisms and the risk of ALL were evaluated by odds ratios (ORs). The heterogeneity and publication bias were estimated. Meta-regression analysis was performed to evaluate the potential sources of heterogeneity. Results C677T polymorphism was associated with a reduced risk of ALL (allele contrast: ORRE = 0.91, 95% CI: 0.83-0.99). Subgroup analysis showed MTHFR C677T variant was associated with decreased susceptibility to ALL in children and Caucasians. Meta-regression showed the logOR for the association between T allele and ALL increased as sex ratio (M/F) in the case group increased (P = 0.01). Regarding A1298C polymorphism, no significant association was observed (allele contrast: ORRE = 1.01, 95% CI: 0.91-1.11). There was no publication bias for C677T or A1298C polymorphism. Conclusions The present meta-analysis suggests that the C677T polymorphism, not A1298C, in MTHFR gene is associated with a decreased risk of ALL, particularly among children and Caucasians subjects. Our findings suggest that the influence of the C677T polymorphism on ALL susceptibility is modified by sex ratio in cases (M/F). Since folate intake may be a possible confounding factor, including this factor in future prospective studies is warranted. Further meta-analysis studies should be at least stratified for folate levels and gender to give more powerful and informative results. PMID:22943282

  6. Mixed waste characterization reference document

    International Nuclear Information System (INIS)

    1997-09-01

    Waste characterization and monitoring are major activities in the management of waste from generation through storage and treatment to disposal. Adequate waste characterization is necessary to ensure safe storage, selection of appropriate and effective treatment, and adherence to disposal standards. For some wastes characterization objectives can be difficult and costly to achieve. The purpose of this document is to evaluate costs of characterizing one such waste type, mixed (hazardous and radioactive) waste. For the purpose of this document, waste characterization includes treatment system monitoring, where monitoring is a supplement or substitute for waste characterization. This document establishes a cost baseline for mixed waste characterization and treatment system monitoring requirements from which to evaluate alternatives. The cost baseline established as part of this work includes costs for a thermal treatment technology (i.e., a rotary kiln incinerator), a nonthermal treatment process (i.e., waste sorting, macronencapsulation, and catalytic wet oxidation), and no treatment (i.e., disposal of waste at the Waste Isolation Pilot Plant (WIPP)). The analysis of improvement over the baseline includes assessment of promising areas for technology development in front-end waste characterization, process equipment, off gas controls, and monitoring. Based on this assessment, an ideal characterization and monitoring configuration is described that minimizes costs and optimizes resources required for waste characterization

  7. Mixed waste characterization reference document

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    Waste characterization and monitoring are major activities in the management of waste from generation through storage and treatment to disposal. Adequate waste characterization is necessary to ensure safe storage, selection of appropriate and effective treatment, and adherence to disposal standards. For some wastes characterization objectives can be difficult and costly to achieve. The purpose of this document is to evaluate costs of characterizing one such waste type, mixed (hazardous and radioactive) waste. For the purpose of this document, waste characterization includes treatment system monitoring, where monitoring is a supplement or substitute for waste characterization. This document establishes a cost baseline for mixed waste characterization and treatment system monitoring requirements from which to evaluate alternatives. The cost baseline established as part of this work includes costs for a thermal treatment technology (i.e., a rotary kiln incinerator), a nonthermal treatment process (i.e., waste sorting, macronencapsulation, and catalytic wet oxidation), and no treatment (i.e., disposal of waste at the Waste Isolation Pilot Plant (WIPP)). The analysis of improvement over the baseline includes assessment of promising areas for technology development in front-end waste characterization, process equipment, off gas controls, and monitoring. Based on this assessment, an ideal characterization and monitoring configuration is described that minimizes costs and optimizes resources required for waste characterization.

  8. Documentation of spectrom-32

    International Nuclear Information System (INIS)

    Callahan, G.D.; Fossum, A.F.; Svalstad, D.K.

    1989-01-01

    SPECTROM-32 is a finite element program for analyzing two-dimensional and axisymmetric inelastic thermomechanical problems related to the geological disposal of nuclear waste. The code is part of the SPECTROM series of special-purpose computer programs that are being developed by RE/SPEC Inc. to address many unique rock mechanics problems encountered in analyzing radioactive wastes stored in geologic formations. This document presents the theoretical basis for the mathematical models, the finite element formulation and solution procedure of the program, a description of the input data for the program, verification problems, and details about program support and continuing documentation. The computer code documentation is intended to satisfy the requirements and guidelines outlined in the document entitled Final Technical Position on Documentation of Computer Codes for High-Level Waste Management. The principal component models used in the program involve thermoelastic, thermoviscoelastic, thermoelastic-plastic, and thermoviscoplastic types of material behavior. Special material considerations provide for the incorporation of limited-tension material behavior and consideration of jointed material behavior. Numerous program options provide the capabilities for various boundary conditions, sliding interfaces, excavation, backfill, arbitrary initial stresses, multiple material domains, load incrementation, plotting database storage and access of results, and other features unique to the geologic disposal of radioactive wastes. Numerous verification problems that exercise many of the program options and illustrate the required data input and printed results are included in the documentation

  9. Technical approach document

    International Nuclear Information System (INIS)

    1988-04-01

    This document describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement Remedial Action Plans (RAPs) and final designs that comply with EPS standards. This document is a revision to the original document. Major revisions were made to the sections in riprap selection and sizing, and ground-water; only minor revisions were made to the remainder of the document. The US Nuclear Regulatory Commission (NRC) has prepared a Standard Review Plan (NRC-SRP) which describes factors to be considered by the NRC in approving the RAP. Sections 3.0, 4.0, 5.0, and 7.0 of this document are arranged under the same headings as those used in the NRC-SRP. This approach is adopted in order to facilitate joint use of the documents. Section 2.0 (not included in the NRC-SRP) discusses design considerations; Section 3.0 describes surface-water hydrology and erosion control; Section 4.0 describes geotechnical aspects of pile design; Section 5.0 discusses the Alternate Site Selection Process; Section 6.0 deals with radiological issues (in particular, the design of the radon barrier); Section 7.0 discusses protection of groundwater resources; and Section 8.0 discusses site design criteria for the RAC

  10. LCS Content Document Application

    Science.gov (United States)

    Hochstadt, Jake

    2011-01-01

    My project at KSC during my spring 2011 internship was to develop a Ruby on Rails application to manage Content Documents..A Content Document is a collection of documents and information that describes what software is installed on a Launch Control System Computer. It's important for us to make sure the tools we use everyday are secure, up-to-date, and properly licensed. Previously, keeping track of the information was done by Excel and Word files between different personnel. The goal of the new application is to be able to manage and access the Content Documents through a single database backed web application. Our LCS team will benefit greatly with this app. Admin's will be able to login securely to keep track and update the software installed on each computer in a timely manner. We also included exportability such as attaching additional documents that can be downloaded from the web application. The finished application will ease the process of managing Content Documents while streamlining the procedure. Ruby on Rails is a very powerful programming language and I am grateful to have the opportunity to build this application.

  11. [Materiality Analysis of Health Plans Based on Stakeholder Engagement and the Issues Included at ISO 26000:2010].

    Science.gov (United States)

    Moyano Santiago, Miguel Angel; Rivera Lirio, Juana María

    2017-01-18

    Health plans of the Spanish autonomous communities can incorporate sustainable development criteria in its development. There have been no analysis or proposals about development and indicators. The goal is to add a contribution to help build better health plans aimed at sustainable development and help to manage economic, social and environmental impacts of health systems criteria. We used a variation of the RAND/UCLA or modified Delphi technique method. The process consisted of a bibliographical and context matters and issues related to health and social responsibility analysis based on ISO 26000: 2010. A survey by deliberately to a selection of 70 expert members of the identified stakeholders was carried out and a discussion group was held to determine the consensus on the issues addressed in the survey sample. The research was conducted in 2015. From the literature review 33 health issues included in ISO 26000:2010 were obtained. 7 survey proved relevant high consensus, 8 relevance and average consensus and 18 with less relevance and high level of dissent. The expert group excluded 4 of the 18 subjects with less consensus. 29 issues included 33 at work, divided into 7 subjects contained in the guide ISO 26000 of social responsibility, were relevant stakeholders regarding possible inclusion in health plans. Considering the direct relationship published by ISO (International Organization for Standardization) among the issues ISO 26000 and the economic, social and environmental indicators in GRI (Global Reporting Initiative) in its G4 version, a panel with monitoring indicators related to relevant issues were elaborated.

  12. Validity of segmental bioelectrical impedance analysis for estimating fat-free mass in children including overweight individuals.

    Science.gov (United States)

    Ohta, Megumi; Midorikawa, Taishi; Hikihara, Yuki; Masuo, Yoshihisa; Sakamoto, Shizuo; Torii, Suguru; Kawakami, Yasuo; Fukunaga, Tetsuo; Kanehisa, Hiroaki

    2017-02-01

    This study examined the validity of segmental bioelectrical impedance (BI) analysis for predicting the fat-free masses (FFMs) of whole-body and body segments in children including overweight individuals. The FFM and impedance (Z) values of arms, trunk, legs, and whole body were determined using a dual-energy X-ray absorptiometry and segmental BI analyses, respectively, in 149 boys and girls aged 6 to 12 years, who were divided into model-development (n = 74), cross-validation (n = 35), and overweight (n = 40) groups. Simple regression analysis was applied to (length) 2 /Z (BI index) for each of the whole-body and 3 segments to develop the prediction equations of the measured FFM of the related body part. In the model-development group, the BI index of each of the 3 segments and whole body was significantly correlated to the measured FFM (R 2 = 0.867-0.932, standard error of estimation = 0.18-1.44 kg (5.9%-8.7%)). There was no significant difference between the measured and predicted FFM values without systematic error. The application of each equation derived in the model-development group to the cross-validation and overweight groups did not produce significant differences between the measured and predicted FFM values and systematic errors, with an exception that the arm FFM in the overweight group was overestimated. Segmental bioelectrical impedance analysis is useful for predicting the FFM of each of whole-body and body segments in children including overweight individuals, although the application for estimating arm FFM in overweight individuals requires a certain modification.

  13. 327 Building hazard baseline document

    International Nuclear Information System (INIS)

    STEFFEN, J.M.

    1999-01-01

    This document identifies the hazards in the 327 Building at the time that a facility walk through was performed during FY99, presents a PHA of stabilization and deactivation activities, and provides a basis for the hazard evaluation and accident analysis that will be developed in the 327 Building Basis for Interim Operation (BIO). Activities addressed in this hazard baseline document include: (1) Stabilization and deactivation activities in preparation for eventual decommissioning of the 327 Building and the routine handling, processing, and shipment of waste to support these activities. (2) 324/327 Building Minimum Safe Project engineering and maintenance activities to maintain the building and systems viable--especially the Safety SSCs--to allow stabilization, deactivation, and waste handling activities with a minimum of risk to workers, the public, and the environment

  14. An Archaeological/Genealogical Historical Analysis of The National Council of Teachers of Mathematics' Standards Documents

    Science.gov (United States)

    Bullock, Erika Catherine

    2013-01-01

    Since the mid-20th century in the United States, there have been several reform movements within mathematics education; each movement has been subject to its own unique socio-cultural and -political forces. The National Council of Teachers of Mathematics' (NCTM) Standards documents--"Curriculum and Evaluation Standards for School…

  15. Meaningful participation for children in the Dutch child protection system : A critical analysis of relevant provisions in policy documents

    NARCIS (Netherlands)

    Bouma, Helen; López López, Mónica; Knorth, Erik J.; Grietens, Hans

    2018-01-01

    Policymakers are increasingly focusing on the participation of children in the child protection system (CPS). However, research shows that actual practice still needs to be improved. Embedding children’s participation in legislation and policy documents is one important prerequisite for achieving

  16. An Analysis of 1926 Inspection Legislation Document, Named: "Law about Inspectors of Education Ministry and Their Authorization"

    Science.gov (United States)

    Usta, Mehmet Emin

    2018-01-01

    In this study, 1926 official legislation document was analyzed taking the role and duties of inspectors at that time in mind. These roles and duties were explained based on the authorization, investigation, interrogation methodology, and employment of inspectors. This study was carried out by implementing documentary research methods. Like other…

  17. The role the safety analysis report and other documents in the licensing procedure in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Albrecht, E.; Ballhaus, S.

    1975-01-01

    Legal requirements for the licensing procedure, requirements for and preparation of licensing documents, authorities and experts participating in the licensing procedure, course of the atomic licensing procedure e.g. application for construction and operation, public hearing, site and concept license, partial licenses. (HP) [de

  18. Improving collaborative documentation in CMS

    International Nuclear Information System (INIS)

    Lassila-Perini, Kati; Salmi, Leena

    2010-01-01

    Complete and up-to-date documentation is essential for efficient data analysis in a large and complex collaboration like CMS. Good documentation reduces the time spent in problem solving for users and software developers. The scientists in our research environment do not necessarily have the interests or skills of professional technical writers. This results in inconsistencies in the documentation. To improve the quality, we have started a multidisciplinary project involving CMS user support and expertise in technical communication from the University of Turku, Finland. In this paper, we present possible approaches to study the usability of the documentation, for instance, usability tests conducted recently for the CMS software and computing user documentation.

  19. 9 CFR 392.4 - Supporting documentation.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Supporting documentation. 392.4 Section 392.4 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... presentation of the data should include a complete statistical analysis using conventional statistical methods. ...

  20. Cost-Utility Analysis of Extending Public Health Insurance Coverage to Include Diabetic Retinopathy Screening by Optometrists.

    Science.gov (United States)

    van Katwyk, Sasha; Jin, Ya-Ping; Trope, Graham E; Buys, Yvonne; Masucci, Lisa; Wedge, Richard; Flanagan, John; Brent, Michael H; El-Defrawy, Sherif; Tu, Hong Anh; Thavorn, Kednapa

    2017-09-01

    Diabetic retinopathy (DR) is one of the leading causes of vision loss and blindness in Canada. Eye examinations play an important role in early detection. However, DR screening by optometrists is not always universally covered by public or private health insurance plans. This study assessed whether expanding public health coverage to include diabetic eye examinations for retinopathy by optometrists is cost-effective from the perspective of the health care system. We conducted a cost-utility analysis of extended coverage for diabetic eye examinations in Prince Edward Island to include examinations by optometrists, not currently publicly covered. We used a Markov chain to simulate disease burden based on eye examination rates and DR progression over a 30-year time horizon. Results were presented as an incremental cost per quality-adjusted life year (QALY) gained. A series of one-way and probabilistic sensitivity analyses were performed. Extending public health coverage to eye examinations by optometrists was associated with higher costs ($9,908,543.32) and improved QALYs (156,862.44), over 30 years, resulting in an incremental cost-effectiveness ratio of $1668.43/QALY gained. Sensitivity analysis showed that the most influential determinants of the results were the cost of optometric screening and selected utility scores. At the commonly used threshold of $50,000/QALY, the probability that the new policy was cost-effective was 99.99%. Extending public health coverage to eye examinations by optometrists is cost-effective based on a commonly used threshold of $50,000/QALY. Findings from this study can inform the decision to expand public-insured optometric services for patients with diabetes. Copyright © 2017 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  1. Customer Communication Document

    Science.gov (United States)

    2009-01-01

    This procedure communicates to the Customers of the Automation, Robotics and Simulation Division (AR&SD) Dynamics Systems Test Branch (DSTB) how to obtain services of the Six-Degrees-Of-Freedom Dynamic Test System (SDTS). The scope includes the major communication documents between the SDTS and its Customer. It established the initial communication and contact points as well as provides the initial documentation in electronic media for the customer. Contact the SDTS Manager (SM) for the names of numbers of the current contact points.

  2. INCLUDING RISK IN ECONOMIC FEASIBILITY ANALYSIS:A STOCHASTIC SIMULATION MODEL FOR BLUEBERRY INVESTMENT DECISIONS IN CHILE

    Directory of Open Access Journals (Sweden)

    GERMÁN LOBOS

    2015-12-01

    Full Text Available ABSTRACT The traditional method of net present value (NPV to analyze the economic profitability of an investment (based on a deterministic approach does not adequately represent the implicit risk associated with different but correlated input variables. Using a stochastic simulation approach for evaluating the profitability of blueberry (Vaccinium corymbosum L. production in Chile, the objective of this study is to illustrate the complexity of including risk in economic feasibility analysis when the project is subject to several but correlated risks. The results of the simulation analysis suggest that the non-inclusion of the intratemporal correlation between input variables underestimate the risk associated with investment decisions. The methodological contribution of this study illustrates the complexity of the interrelationships between uncertain variables and their impact on the convenience of carrying out this type of business in Chile. The steps for the analysis of economic viability were: First, adjusted probability distributions for stochastic input variables (SIV were simulated and validated. Second, the random values of SIV were used to calculate random values of variables such as production, revenues, costs, depreciation, taxes and net cash flows. Third, the complete stochastic model was simulated with 10,000 iterations using random values for SIV. This result gave information to estimate the probability distributions of the stochastic output variables (SOV such as the net present value, internal rate of return, value at risk, average cost of production, contribution margin and return on capital. Fourth, the complete stochastic model simulation results were used to analyze alternative scenarios and provide the results to decision makers in the form of probabilities, probability distributions, and for the SOV probabilistic forecasts. The main conclusion shown that this project is a profitable alternative investment in fruit trees in

  3. Is Serum Hypovitaminosis D Associated with Chronic Widespread Pain Including Fibromyalgia? A Meta-analysis of Observational Studies.

    Science.gov (United States)

    Hsiao, Ming-Yen; Hung, Chen-Yu; Chang, Ke-Vin; Han, Der-Sheng; Wang, Tyng-Guey

    2015-01-01

    Chronic widespread pain (CWP) is a global musculoskeletal disorder leading to disability and a reduced quality of life. Low levels of serum vitamin D has long been proposed to be associated with CWP, but previous research remains inconclusive. To determine whether hypovitaminosis D was independently associated with CWP. Meta-analysis of observational study. Electronic databases were searched for studies published up to November 2014 comparing the prevalence of hypovitaminosis D and serum vitamin D levels between participants with and without CWP. The crude and adjusted odds ratios (ORs) of hypovitaminosis D with CWP were calculated. Subgroup analysis according to gender, threshold of hypovitaminosis, and definition of patients was performed, as well as meta-regression to test the linear relationship between crude ORs and the latitude of study locations. Twelve studies were included, comprising 1,854 patients with CWP. The patient group showed a significantly higher risk of hypovitaminosis D than the control group (crude OR, 1.63; 95% CI, 1.20-2.23). The association was slightly attenuated after adjusting confounders, with a pooled adjusted OR of 1.41 (95% CI, 1.00-2.00). There was an increase in ORs of hypovitaminosis D using a lower diagnostic value of serum vitamin D (8 and 10 ng/mL). The subgroup analysis according to gender and definition of CWP did not reveal significant between-group differences. The meta-regression showed no linear relationship between latitude and the crude ORs. There was a positive crude association between hypovitaminosis D and CWP, and the association was likely to remain after adjusting confounding factors. Use of a cut-off value of hypovitaminosis D (8-10 ng/mL) could better define the population with and without CWP. Further prospective follow-up studies are warranted to clarify the causal relationship between hypovitaminosis D and CWP.

  4. Cf-252 Characterization Documents

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, Alexander [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-03-14

    Six documents were written by Vance and Associates under contract to the Off-Site Source Recovery Project of Los Alamos National Laboratory. These Six documents provided the basis for characterization of Californium-252 sealed sources and for the packaging and manifesting of this material for disposal at the Waste Isolation Pilot Project. The Six documents are: 1. VA-OSR-10, Development of radionuclide distributions for Cf-252 sealed sources. 2. VA-OSR-11, Uncertainty analysis for Cf-252 sealed sources. 3. VA-OSR-12, To determine the radionuclides in the waste drums containing Cf-252 sealed source waste that are required to be reported under the requirements of the WIPP WAC and the TRAMPAC. 4. VA-OSR-13, Development of the spreadsheet for the radiological calculations for the characterization of Cf-252 sources. 5. VA-OSR-14, Relative importance of neutron-induced fission in Cf-252 sources. 6. VA-OSR-15, Determine upper bound of decay product inventories from a drum of Cf-252 sources. These six documents provide the technical basis for the characterization of Cf-252 sources and will be part of the AK documentation required for submittal to the Central Characterization Project (CCP) of WIPP.

  5. Including People with Dementia in Research: An Analysis of Australian Ethical and Legal Rules and Recommendations for Reform.

    Science.gov (United States)

    Ries, Nola M; Thompson, Katie A; Lowe, Michael

    2017-09-01

    Research is crucial to advancing knowledge about dementia, yet the burden of the disease currently outpaces research activity. Research often excludes people with dementia and other cognitive impairments because researchers and ethics committees are concerned about issues related to capacity, consent, and substitute decision-making. In Australia, participation in research by people with cognitive impairment is governed by a national ethics statement and a patchwork of state and territorial laws that have widely varying rules. We contend that this legislative variation precludes a consistent approach to research governance and participation and hinders research that seeks to include people with impaired capacity. In this paper, we present key ethical principles, provide a comprehensive review of applicable legal rules in Australian states and territories, and highlight significant differences and ambiguities. Our analysis includes recommendations for reform to improve clarity and consistency in the law and reduce barriers that may exclude persons with dementia from participating in ethically approved research. Our recommendations seek to advance the national decision-making principles recommended by the Australian Law Reform Commission, which emphasize the rights of all adults to make their own decisions and for those with impaired capacity to have access to appropriate supports to help them make decisions that affect their lives.

  6. CeCaFDB: a curated database for the documentation, visualization and comparative analysis of central carbon metabolic flux distributions explored by 13C-fluxomics.

    Science.gov (United States)

    Zhang, Zhengdong; Shen, Tie; Rui, Bin; Zhou, Wenwei; Zhou, Xiangfei; Shang, Chuanyu; Xin, Chenwei; Liu, Xiaoguang; Li, Gang; Jiang, Jiansi; Li, Chao; Li, Ruiyuan; Han, Mengshu; You, Shanping; Yu, Guojun; Yi, Yin; Wen, Han; Liu, Zhijie; Xie, Xiaoyao

    2015-01-01

    The Central Carbon Metabolic Flux Database (CeCaFDB, available at http://www.cecafdb.org) is a manually curated, multipurpose and open-access database for the documentation, visualization and comparative analysis of the quantitative flux results of central carbon metabolism among microbes and animal cells. It encompasses records for more than 500 flux distributions among 36 organisms and includes information regarding the genotype, culture medium, growth conditions and other specific information gathered from hundreds of journal articles. In addition to its comprehensive literature-derived data, the CeCaFDB supports a common text search function among the data and interactive visualization of the curated flux distributions with compartmentation information based on the Cytoscape Web API, which facilitates data interpretation. The CeCaFDB offers four modules to calculate a similarity score or to perform an alignment between the flux distributions. One of the modules was built using an inter programming algorithm for flux distribution alignment that was specifically designed for this study. Based on these modules, the CeCaFDB also supports an extensive flux distribution comparison function among the curated data. The CeCaFDB is strenuously designed to address the broad demands of biochemists, metabolic engineers, systems biologists and members of the -omics community. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  7. Cigarette company trade secrets are not secret: an analysis of reverse engineering reports in internal tobacco industry documents released as a result of litigation

    Science.gov (United States)

    Velicer, Clayton; Lempert, Lauren K; Glantz, Stanton

    2014-01-01

    Objectives Use previously secret tobacco industry documents to assess tobacco companies’ routine claims of trade secret protection for information on cigarette ingredients, additives and construction made to regulatory agencies, as well as the companies’ refusal to publicly disclose this information. Methods We analysed previously secret tobacco industry documents available at (http://legacy.library.ucsf.edu) to identify 100 examples of seven major tobacco companies’ reverse engineering of their competitors’ brands between 1937 and 2001. Results These reverse engineering reports contain detailed data for 142 different measurements for at least two companies, including physical parameters of the cigarettes, tobacco types, humectants, additives, flavourings, and smoke constituents of competitors’ cigarettes. These 100 documents were distributed to 564 employees, including top managers in domestic and foreign offices across multiple departments, including executive leadership, research and design, product development, marketing and legal. These documents reported new competitors’ products, measured ingredient changes over time, and informed companies’ decisions regarding ingredients in their own products. Conclusions Because cigarette companies routinely analyse their competitors’ cigarettes in great detail, this information is neither secret nor commercially valuable and, thus, does not meet the legal definition of a ‘trade secret.’ This information is only being kept ‘secret’ from the people consuming cigarettes and the scientific community. Public agencies should release this detailed information because it would provide valuable information about how ingredients affect addictiveness and toxicity, and would help the public health community and consumers better understand the impact of cigarette design on human health. PMID:24920577

  8. Elevation of sulfatides in ovarian cancer: An integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry

    Directory of Open Access Journals (Sweden)

    McDonald John F

    2010-07-01

    Full Text Available Abstract Background Sulfatides (ST are a category of sulfated galactosylceramides (GalCer that are elevated in many types of cancer including, possibly, ovarian cancer. Previous evidence for elevation of ST in ovarian cancer was based on a colorimetric reagent that does not provide structural details and can also react with other lipids. Therefore, this study utilized mass spectrometry for a structure-specific and quantitative analysis of the types, amounts, and tissue localization of ST in ovarian cancer, and combined these findings with analysis of mRNAs for the relevant enzymes of ST metabolism to explore possible mechanisms. Results Analysis of 12 ovarian tissues graded as histologically normal or having epithelial ovarian tumors by liquid chromatography electrospray ionization-tandem mass spectrometry (LC ESI-MS/MS established that most tumor-bearing tissues have higher amounts of ST. Because ovarian cancer tissues are comprised of many different cell types, histological tissue slices were analyzed by matrix-assisted laser desorption ionization-tissue-imaging MS (MALDI-TIMS. The regions where ST were detected by MALDI-TIMS overlapped with the ovarian epithelial carcinoma as identified by H & E staining and histological scoring. Furthermore, the structures for the most prevalent species observed via MALDI-TIMS (d18:1/C16:0-, d18:1/C24:1- and d18:1/C24:0-ST were confirmed by MALDI-TIMS/MS, whereas, a neighboring ion(m/z 885.6 that was not tumor specific was identified as a phosphatidylinositol. Microarray analysis of mRNAs collected using laser capture microdissection revealed that expression of GalCer synthase and Gal3ST1 (3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase were approximately 11- and 3.5-fold higher, respectively, in the ovarian epithelial carcinoma cells versus normal ovarian stromal tissue, and they were 5- and 2.3-fold higher in comparison with normal surface ovarian epithelial cells, which is a likely

  9. Sugar Industry Influence on the Scientific Agenda of the National Institute of Dental Research’s 1971 National Caries Program: A Historical Analysis of Internal Documents

    Science.gov (United States)

    Kearns, Cristin E.; Glantz, Stanton A.; Schmidt, Laura A.

    2015-01-01

    Background In 1966, the National Institute of Dental Research (NIDR) began planning a targeted research program to identify interventions for widespread application to eradicate dental caries (tooth decay) within a decade. In 1971, the NIDR launched the National Caries Program (NCP). The objective of this paper is to explore the sugar industry’s interaction with the NIDR to alter the research priorities of the NIDR NCP. Methods and Findings We used internal cane and beet sugar industry documents from 1959 to 1971 to analyze industry actions related to setting research priorities for the NCP. The sugar industry could not deny the role of sucrose in dental caries given the scientific evidence. They therefore adopted a strategy to deflect attention to public health interventions that would reduce the harms of sugar consumption rather than restricting intake. Industry tactics included the following: funding research in collaboration with allied food industries on enzymes to break up dental plaque and a vaccine against tooth decay with questionable potential for widespread application, cultivation of relationships with the NIDR leadership, consulting of members on an NIDR expert panel, and submission of a report to the NIDR that became the foundation of the first request for proposals issued for the NCP. Seventy-eight percent of the sugar industry submission was incorporated into the NIDR’s call for research applications. Research that could have been harmful to sugar industry interests was omitted from priorities identified at the launch of the NCP. Limitations are that this analysis relies on one source of sugar industry documents and that we could not interview key actors. Conclusions The NCP was a missed opportunity to develop a scientific understanding of how to restrict sugar consumption to prevent tooth decay. A key factor was the alignment of research agendas between the NIDR and the sugar industry. This historical example illustrates how industry protects

  10. Gaia DR1 documentation

    Science.gov (United States)

    van Leeuwen, F.; de Bruijne, J. H. J.; Arenou, F.; Comoretto, G.; Eyer, L.; Farras Casas, M.; Hambly, N.; Hobbs, D.; Salgado, J.; Utrilla Molina, E.; Vogt, S.; van Leeuwen, M.; Abreu, A.; Altmann, M.; Andrei, A.; Babusiaux, C.; Bastian, U.; Biermann, M.; Blanco-Cuaresma, S.; Bombrun, A.; Borrachero, R.; Brown, A. G. A.; Busonero, D.; Busso, G.; Butkevich, A.; Cantat-Gaudin, T.; Carrasco, J. M.; Castañeda, J.; Charnas, J.; Cheek, N.; Clementini, G.; Crowley, C.; Cuypers, J.; Davidson, M.; De Angeli, F.; De Ridder, J.; Evans, D.; Fabricius, C.; Findeisen, K.; Fleitas, J. M.; Gracia, G.; Guerra, R.; Guy, L.; Helmi, A.; Hernandez, J.; Holl, B.; Hutton, A.; Klioner, S.; Lammers, U.; Lecoeur-Taïbi, I.; Lindegren, L.; Luri, X.; Marinoni, S.; Marrese, P.; Messineo, R.; Michalik, D.; Mignard, F.; Montegriffo, P.; Mora, A.; Mowlavi, N.; Nienartowicz, K.; Pancino, E.; Panem, C.; Portell, J.; Rimoldini, L.; Riva, A.; Robin, A.; Siddiqui, H.; Smart, R.; Sordo, R.; Soria, S.; Turon, C.; Vallenari, A.; Voss, H.

    2017-12-01

    We present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7 in the white-light photometric band G of Gaia. The Gaia Data Processing and Analysis Consortium (DPAC) processed the raw measurements collected with the Gaia instruments during the first 14 months of the mission, and turned these into an astrometric and photometric catalogue. Gaia DR1 consists of three parts: an astrometric data set which contains the positions, parallaxes, and mean proper motions for about 2 million of the brightest stars in common with the Hipparcos and Tycho-2 catalogues (the primary astrometric data set) and the positions for an additional 1.1 billion sources (the secondary astrometric data set). The primary set forms the realisation of the Tycho-Gaia Astrometric Solution (TGAS). The second part of Gaia DR1 is the photometric data set, which contains the mean G-band magnitudes for all sources. The third part consists of the G-band light curves and the characteristics of 3000 Cepheid and RR Lyrae stars observed at high cadence around the south ecliptic pole. The positions and proper motions in the astrometric data set are given in a reference frame that is aligned with the International Celestial Reference Frame (ICRF) to better than 0.1 mas at epoch J2015.0, and non-rotating with respect to the ICRF to within 0.03 mas yr^-1. For the primary astrometric data set, the typical standard error for the positions and parallaxes is about 0.3 mas, while for the proper motions the typical standard error is about 1 mas yr^-1. Whereas it has been suggested in Gaia Collaboration et al. (2016a) that a systematic component of ∼0.3 mas should be 'added' (in quadrature) to the parallax uncertainties, Brown (2017) clarifies that reported parallax standard errors already include local systematics as a result of the calibration of the TGAS parallax uncertainties by comparison to Hipparcos parallaxes. For the subset of

  11. In situ analysis of historical documents through a portable system of X RF; Analisis In situ de documentos historicos mediante un sistema portatil de FRX

    Energy Technology Data Exchange (ETDEWEB)

    Ruvalcaba S, J.L. [IFUNAM, A.P. 20-364, 01000 Mexico D.F. (Mexico); Gonzalez T, C. [Biblioteca Nacional de Antropologia e Historia, INAH, 11560 Mexico D.F. (Mexico)

    2005-07-01

    From the analysis of the documents and ancient books, the chronology of documents, the use of materials (paper, parchment, inks, pigments) and deterioration, among others aspects may be determined. Usually it is difficult to bring the object to the laboratory for analysis and it is not possible to sample (even small portions). Due to the importance of the documents characterization, it is necessary to carry out a diagnostic analysis at the library in order to establish the general nature of the materials (organic or inorganic), the main composition of inks and pigments, actual and possible deterioration. From this point of view, X-ray fluorescence analysis (X RF) with a portable system, may be used for quick non-destructive elemental composition determinations. A X RF system was specially developed at the Physics Institute (UNAM) for these purposes and it may be used out of the laboratory in libraries and museums. In this work, our X RF methodology is described and the study of inks of manuscripts from 15 Th and 16 Th centuries belonging to the National Anthropology and History Library is presented. (Author)

  12. Combining Antidepressants in Acute Treatment of Depression: A Meta-Analysis of 38 Studies Including 4511 Patients

    Science.gov (United States)

    Henssler, Jonathan; Bschor, Tom

    2016-01-01

    Objective: Combining antidepressants (ADs) for therapy of acute depression is frequently employed, but randomized studies have yielded conflicting results. We conducted a systematic review and meta-analysis aimed at determining efficacy and tolerability of combination therapy. Methods: MEDLINE, Embase, PsycINFO, and CENTRAL databases were systematically searched through March 2014 for controlled studies comparing combinations of ADs with AD monotherapy in adult patients suffering from acute depression. The prespecified primary outcome was standardized mean difference (SMD), secondary outcomes were response, remission, and dropouts. Results: Among 8688 articles screened, 38 studies were eligible, including 4511 patients. Combination treatment was statistically, significantly superior to monotherapy (SMD 0.29; 95% CI 0.16 to 0.42). During monotherapy, slightly fewer patients dropped out due to adverse events (OR 0.90; 95% CI 0.53 to 1.53). Studies were heterogeneous (I2 = 63%), and there was indication of moderate publication bias (fail-safe N for an effect of 0.1:44), but results remained robust across prespecified secondary outcomes and subgroups, including analyses restricted to randomized controlled trials and low risk of bias studies. Meta-regression revealed an association of SMD with difference in imipramine-equivalent dose. Combining a reuptake inhibitor with an antagonist of presynaptic α2-autoreceptors was superior to other combinations. Conclusion: Combining ADs seems to be superior to monotherapy with only slightly more patients dropping out. Combining a reuptake inhibitor with an antagonist of presynaptic α2-autoreceptors seems to be significantly more effective than other combinations. Overall, our search revealed a dearth of well-designed studies. PMID:27582451

  13. Combining Antidepressants in Acute Treatment of Depression: A Meta-Analysis of 38 Studies Including 4511 Patients.

    Science.gov (United States)

    Henssler, Jonathan; Bschor, Tom; Baethge, Christopher

    2016-01-01

    Combining antidepressants (ADs) for therapy of acute depression is frequently employed, but randomized studies have yielded conflicting results. We conducted a systematic review and meta-analysis aimed at determining efficacy and tolerability of combination therapy. MEDLINE, Embase, PsycINFO, and CENTRAL databases were systematically searched through March 2014 for controlled studies comparing combinations of ADs with AD monotherapy in adult patients suffering from acute depression. The prespecified primary outcome was standardized mean difference (SMD), secondary outcomes were response, remission, and dropouts. Among 8688 articles screened, 38 studies were eligible, including 4511 patients. Combination treatment was statistically, significantly superior to monotherapy (SMD 0.29; 95% CI 0.16 to 0.42). During monotherapy, slightly fewer patients dropped out due to adverse events (OR 0.90; 95% CI 0.53 to 1.53). Studies were heterogeneous (I(2) = 63%), and there was indication of moderate publication bias (fail-safe N for an effect of 0.1:44), but results remained robust across prespecified secondary outcomes and subgroups, including analyses restricted to randomized controlled trials and low risk of bias studies. Meta-regression revealed an association of SMD with difference in imipramine-equivalent dose. Combining a reuptake inhibitor with an antagonist of presynaptic α2-autoreceptors was superior to other combinations. Combining ADs seems to be superior to monotherapy with only slightly more patients dropping out. Combining a reuptake inhibitor with an antagonist of presynaptic α2-autoreceptors seems to be significantly more effective than other combinations. Overall, our search revealed a dearth of well-designed studies. © The Author(s) 2016.

  14. Evaluating public involvement in research design and grant development: Using a qualitative document analysis method to analyse an award scheme for researchers.

    Science.gov (United States)

    Baxter, Susan; Muir, Delia; Brereton, Louise; Allmark, Christine; Barber, Rosemary; Harris, Lydia; Hodges, Brian; Khan, Samaira; Baird, Wendy

    2016-01-01

    money was used, including a description of the aims and outcomes of the public involvement activities. The purpose of this study was to analyse the content of these reports. We aimed to find out what researcher views and experiences of public involvement activities were, and what lessons might be learned. Methods We used an innovative method of data analysis, drawing on group participatory approaches, qualitative content analysis, and Framework Analysis to sort and label the content of the reports. We developed a framework of categories and sub-categories (or themes and sub-themes) from this process. Results Twenty five documents were analysed. Four main themes were identified in the data: the added value of public involvement; planning and designing involvement; the role of public members; and valuing public member contributions. Within these themes, sub-themes related to the timing of involvement (prior to the research study/intended during the research study), and also specific benefits of public involvement such as: validating ideas; ensuring appropriate outcomes; ensuring the acceptability of data collection methods/tools and advice regarding research processes. Other sub-themes related to: finding and approaching public members; timing of events; training/support; the format of sessions; setting up public involvement panels: use of public contributors in analysis and interpretation of data; and using public members to assist with dissemination and translation into practice. Conclusions The analysis of reports submitted by researchers following involvement events provides evidence of the value of public involvement during the development of applications for research funding, and details a method for involving members of the public in data analysis which could be of value to other researchers The findings of the analysis indicate recognition amongst researchers of the variety in potential roles for public members in research, and also an acknowledgement of how

  15. Finite Element Modeling and Analysis of Nonlinear Impact and Frictional Motion Responses Including Fluid—Structure Coupling Effects

    Directory of Open Access Journals (Sweden)

    Yong Zhao

    1997-01-01

    Full Text Available A nonlinear three dimensional (3D single rack model and a nonlinear 3D whole pool multi-rack model are developed for the spent fuel storage racks of a nuclear power plant (NPP to determine impacts and frictional motion responses when subjected to 3D excitations from the supporting building floor. The submerged free standing rack system and surrounding water are coupled due to hydrodynamic fluid-structure interaction (FSI using potential theory. The models developed have features that allow consideration of geometric and material nonlinearities including (1 the impacts of fuel assemblies to rack cells, a rack to adjacent racks or pool walls, and rack support legs to the pool floor; (2 the hydrodynamic coupling of fuel assemblies with their storing racks, and of a rack with adjacent racks, pool walls, and the pool floor; and (3 the dynamic motion behavior of rocking, twisting, and frictional sliding of rack modules. Using these models 3D nonlinear time history dynamic analyses are performed per the U.S. Nuclear Regulatory Commission (USNRC criteria. Since few such modeling, analyses, and results using both the 3D single and whole pool multiple rack models are available in the literature, this paper emphasizes description of modeling and analysis techniques using the SOLVIA general purpose nonlinear finite element code. Typical response results with different Coulomb friction coefficients are presented and discussed.

  16. Tobacco Industry Manipulation of Tobacco Excise and Tobacco Advertising Policies in the Czech Republic: An Analysis of Tobacco Industry Documents

    Science.gov (United States)

    Shirane, Risako; Smith, Katherine; Ross, Hana; Silver, Karin E.; Williams, Simon; Gilmore, Anna

    2012-01-01

    Background The Czech Republic has one of the poorest tobacco control records in Europe. This paper examines transnational tobacco companies' (TTCs') efforts to influence policy there, paying particular attention to excise policies, as high taxes are one of the most effective means of reducing tobacco consumption, and tax structures are an important aspect of TTC competitiveness. Methods and Findings TTC documents dating from 1989 to 2004/5 were retrieved from the Legacy Tobacco Documents Library website, analysed using a socio-historical approach, and triangulated with key informant interviews and secondary data. The documents demonstrate significant industry influence over tobacco control policy. Philip Morris (PM) ignored, overturned, and weakened various attempts to restrict tobacco advertising, promoting voluntary approaches as an alternative to binding legislation. PM and British American Tobacco (BAT) lobbied separately on tobacco tax structures, each seeking to implement the structure that benefitted its own brand portfolio over that of its competitors, and enjoying success in turn. On excise levels, the different companies took a far more collaborative approach, seeking to keep tobacco taxes low and specifically to prevent any large tax increases. Collective lobbying, using a variety of arguments, was successful in delaying the tax increases required via European Union accession. Contrary to industry arguments, data show that cigarettes became more affordable post-accession and that TTCs have taken advantage of low excise duties by raising prices. Interview data suggest that TTCs enjoy high-level political support and continue to actively attempt to influence policy. Conclusion There is clear evidence of past and ongoing TTC influence over tobacco advertising and excise policy. We conclude that this helps explain the country's weak tobacco control record. The findings suggest there is significant scope for tobacco tax increases in the Czech Republic and

  17. Forensic discrimination of blue ballpoint pens on documents by laser ablation inductively coupled plasma mass spectrometry and multivariate analysis.

    Science.gov (United States)

    Alamilla, Francisco; Calcerrada, Matías; García-Ruiz, Carmen; Torre, Mercedes

    2013-05-10

    The differentiation of blue ballpoint pen inks written on documents through an LA-ICP-MS methodology is proposed. Small common office paper portions containing ink strokes from 21 blue pens of known origin were cut and measured without any sample preparation. In a first step, Mg, Ca and Sr were proposed as internal standards (ISs) and used in order to normalize elemental intensities and subtract background signals from the paper. Then, specific criteria were designed and employed to identify target elements (Li, V, Mn, Co, Ni, Cu, Zn, Zr, Sn, W and Pb) which resulted independent of the IS chosen in a 98% of the cases and allowed a qualitative clustering of the samples. In a second step, an elemental-related ratio (ink ratio) based on the targets previously identified was used to obtain mass independent intensities and perform pairwise comparisons by means of multivariate statistical analyses (MANOVA, Tukey's HSD and T2 Hotelling). This treatment improved the discrimination power (DP) and provided objective results, achieving a complete differentiation among different brands and a partial differentiation within pen inks from the same brands. The designed data treatment, together with the use of multivariate statistical tools, represents an easy and useful tool for differentiating among blue ballpoint pen inks, with hardly sample destruction and without the need for methodological calibrations, being its use potentially advantageous from a forensic-practice standpoint. To test the procedure, it was applied to analyze real handwritten questioned contracts, previously studied by the Department of Forensic Document Exams of the Criminalistics Service of Civil Guard (Spain). The results showed that all questioned ink entries were clustered in the same group, being those different from the remaining ink on the document. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  18. From organizational integration to clinical integration: analysis of the path between one level of integration to another using official documents

    Science.gov (United States)

    Mandza, Matey; Gagnon, Dominique; Carrier, Sébastien; Belzile, Louise; Demers, Louis

    2010-01-01

    Purpose Services’ integration comprises organizational, normative, economic, informational and clinical dimensions. Since 2004, the province of Quebec has devoted significant efforts to unify the governance of the main health and social care organizations of its various territories. Notwithstanding the uniformity of the national plan’s prescription, the territorial integration modalities greatly vary across the province. Theory This research is based upon a conceptual model of integration that comprises six components: inter-organizational partnership, case management, standardized assessment, a single entry point, a standardized service planning tool and a shared clinical file. Methods We conducted an embedded case study in six contrasted sites in terms of their level of integration. All documents prescribing the implementation of integration were retrieved and analyzed. Results and conclusions The analyzed documents demonstrate a growing local appropriation of the current integrative reform. Interestingly however, no link seems to exist between the quality of local prescriptions and the level of integration achieved in each site. This finding leads us to hypothesize that the variable quality of the operational accompaniment offered to implement these prescriptions is a variable in play.

  19. Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis

    Directory of Open Access Journals (Sweden)

    Malik Assaf

    2012-11-01

    Full Text Available Abstract Background The development of complex responses to hypoxia has played a key role in the evolution of mammals, as inadequate response to this condition is frequently associated with cardiovascular diseases, developmental disorders, and cancers. Though numerous studies have used mice and rats in order to explore mechanisms that contribute to hypoxia tolerance, these studies are limited due to the high sensitivity of most rodents to severe hypoxia. The blind subterranean mole rat Spalax is a hypoxia tolerant rodent, which exhibits unique longevity and therefore has invaluable potential in hypoxia and cancer research. Results Using microarrays, transcript abundance was measured in brain and muscle tissues from Spalax and rat individuals exposed to acute and chronic hypoxia for varying durations. We found that Spalax global gene expression response to hypoxia differs from that of rat and is characterized by the activation of functional groups of genes that have not been strongly associated with the response to hypoxia in hypoxia sensitive mammals. Using functional enrichment analysis of Spalax hypoxia induced genes we found highly significant overrepresentation of groups of genes involved in anti apoptosis, cancer, embryonic/sexual development, epidermal growth factor receptor binding, coordinated suppression and activation of distinct groups of transcription factors and membrane receptors, in addition to angiogenic related processes. We also detected hypoxia induced increases of different critical Spalax hub gene transcripts, including antiangiogenic genes associated with cancer tolerance in Down syndrome human individuals. Conclusions This is the most comprehensive study of Spalax large scale gene expression response to hypoxia to date, and the first to use custom Spalax microarrays. Our work presents novel patterns that may underlie mechanisms with critical importance to the evolution of hypoxia tolerance, with special relevance to

  20. Clinical documentation: composition or synthesis?

    Science.gov (United States)

    Mamykina, Lena; Vawdrey, David K; Stetson, Peter D; Zheng, Kai; Hripcsak, George

    2012-01-01

    To understand the nature of emerging electronic documentation practices, disconnects between documentation workflows and computing systems designed to support them, and ways to improve the design of electronic documentation systems. Time-and-motion study of resident physicians' note-writing practices using a commercial electronic health record system that includes an electronic documentation module. The study was conducted in the general medicine unit of a large academic hospital. During the study, 96 note-writing sessions by 11 resident physicians, resulting in close to 100 h of observations were seen. Seven of the 10 most common transitions between activities during note composition were between documenting, and gathering and reviewing patient data, and updating the plan of care. The high frequency of transitions seen in the study suggested that clinical documentation is fundamentally a synthesis activity, in which clinicians review available patient data and summarize their impressions and judgments. At the same time, most electronic health record systems are optimized to support documentation as uninterrupted composition. This mismatch leads to fragmentation in clinical work, and results in inefficiencies and workarounds. In contrast, we propose that documentation can be best supported with tools that facilitate data exploration and search for relevant information, selective reading and annotation, and composition of a note as a temporal structure. Time-and-motion study of clinicians' electronic documentation practices revealed a high level of fragmentation of documentation activities and frequent task transitions. Treating documentation as synthesis rather than composition suggests new possibilities for supporting it more effectively with electronic systems.

  1. Cueing musical emotions: An empirical analysis of 24-piece sets by Bach and Chopin documents parallels with emotional speech.

    Science.gov (United States)

    Poon, Matthew; Schutz, Michael

    2015-01-01

    Acoustic cues such as pitch height and timing are effective at communicating emotion in both music and speech. Numerous experiments altering musical passages have shown that higher and faster melodies generally sound "happier" than lower and slower melodies, findings consistent with corpus analyses of emotional speech. However, equivalent corpus analyses of complex time-varying cues in music are less common, due in part to the challenges of assembling an appropriate corpus. Here, we describe a novel, score-based exploration of the use of pitch height and timing in a set of "balanced" major and minor key compositions. Our analysis included all 24 Preludes and 24 Fugues from Bach's Well-Tempered Clavier (book 1), as well as all 24 of Chopin's Preludes for piano. These three sets are balanced with respect to both modality (major/minor) and key chroma ("A," "B," "C," etc.). Consistent with predictions derived from speech, we found major-key (nominally "happy") pieces to be two semitones higher in pitch height and 29% faster than minor-key (nominally "sad") pieces. This demonstrates that our balanced corpus of major and minor key pieces uses low-level acoustic cues for emotion in a manner consistent with speech. A series of post hoc analyses illustrate interesting trade-offs, with sets featuring greater emphasis on timing distinctions between modalities exhibiting the least pitch distinction, and vice-versa. We discuss these findings in the broader context of speech-music research, as well as recent scholarship exploring the historical evolution of cue use in Western music.

  2. Extremely secure identification documents

    Energy Technology Data Exchange (ETDEWEB)

    Tolk, K.M. [Sandia National Labs., Albuquerque, NM (United States); Bell, M. [Sandia National Labs., Livermore, CA (United States)

    1997-09-01

    The technology developed in this project uses biometric information printed on the document and public key cryptography to ensure that an adversary cannot issue identification documents to unauthorized individuals or alter existing documents to allow their use by unauthorized individuals. This process can be used to produce many types of identification documents with much higher security than any currently in use. The system is demonstrated using a security badge as an example. This project focused on the technologies requiring development in order to make the approach viable with existing badge printing and laminating technologies. By far the most difficult was the image processing required to verify that the picture on the badge had not been altered. Another area that required considerable work was the high density printed data storage required to get sufficient data on the badge for verification of the picture. The image processing process was successfully tested, and recommendations are included to refine the badge system to ensure high reliability. A two dimensional data array suitable for printing the required data on the badge was proposed, but testing of the readability of the array had to be abandoned due to reallocation of the budgeted funds by the LDRD office.

  3. Extremely secure identification documents

    International Nuclear Information System (INIS)

    Tolk, K.M.; Bell, M.

    1997-09-01

    The technology developed in this project uses biometric information printed on the document and public key cryptography to ensure that an adversary cannot issue identification documents to unauthorized individuals or alter existing documents to allow their use by unauthorized individuals. This process can be used to produce many types of identification documents with much higher security than any currently in use. The system is demonstrated using a security badge as an example. This project focused on the technologies requiring development in order to make the approach viable with existing badge printing and laminating technologies. By far the most difficult was the image processing required to verify that the picture on the badge had not been altered. Another area that required considerable work was the high density printed data storage required to get sufficient data on the badge for verification of the picture. The image processing process was successfully tested, and recommendations are included to refine the badge system to ensure high reliability. A two dimensional data array suitable for printing the required data on the badge was proposed, but testing of the readability of the array had to be abandoned due to reallocation of the budgeted funds by the LDRD office

  4. "Working the system"--British American tobacco's influence on the European union treaty and its implications for policy: an analysis of internal tobacco industry documents.

    Directory of Open Access Journals (Sweden)

    Katherine E Smith

    2010-01-01

    Full Text Available Impact assessment (IA of all major European Union (EU policies is now mandatory. The form of IA used has been criticised for favouring corporate interests by overemphasising economic impacts and failing to adequately assess health impacts. Our study sought to assess how, why, and in what ways corporations, and particularly the tobacco industry, influenced the EU's approach to IA.In order to identify whether industry played a role in promoting this system of IA within the EU, we analysed internal documents from British American Tobacco (BAT that were disclosed following a series of litigation cases in the United States. We combined this analysis with one of related literature and interviews with key informants. Our analysis demonstrates that from 1995 onwards BAT actively worked with other corporate actors to successfully promote a business-oriented form of IA that favoured large corporations. It appears that BAT favoured this form of IA because it could advance the company's European interests by establishing ground rules for policymaking that would: (i provide an economic framework for evaluating all policy decisions, implicitly prioritising costs to businesses; (ii secure early corporate involvement in policy discussions; (iii bestow the corporate sector with a long-term advantage over other actors by increasing policymakers' dependence on information they supplied; and (iv provide businesses with a persuasive means of challenging potential and existing legislation. The data reveal that an ensuing lobbying campaign, largely driven by BAT, helped secure binding changes to the EU Treaty via the Treaty of Amsterdam that required EU policymakers to minimise legislative burdens on businesses. Efforts subsequently focused on ensuring that these Treaty changes were translated into the application of a business orientated form of IA (cost-benefit analysis [CBA] within EU policymaking procedures. Both the tobacco and chemical industries have since

  5. "Working the system"--British American tobacco's influence on the European union treaty and its implications for policy: an analysis of internal tobacco industry documents.

    Science.gov (United States)

    Smith, Katherine E; Fooks, Gary; Collin, Jeff; Weishaar, Heide; Mandal, Sema; Gilmore, Anna B

    2010-01-12

    Impact assessment (IA) of all major European Union (EU) policies is now mandatory. The form of IA used has been criticised for favouring corporate interests by overemphasising economic impacts and failing to adequately assess health impacts. Our study sought to assess how, why, and in what ways corporations, and particularly the tobacco industry, influenced the EU's approach to IA. In order to identify whether industry played a role in promoting this system of IA within the EU, we analysed internal documents from British American Tobacco (BAT) that were disclosed following a series of litigation cases in the United States. We combined this analysis with one of related literature and interviews with key informants. Our analysis demonstrates that from 1995 onwards BAT actively worked with other corporate actors to successfully promote a business-oriented form of IA that favoured large corporations. It appears that BAT favoured this form of IA because it could advance the company's European interests by establishing ground rules for policymaking that would: (i) provide an economic framework for evaluating all policy decisions, implicitly prioritising costs to businesses; (ii) secure early corporate involvement in policy discussions; (iii) bestow the corporate sector with a long-term advantage over other actors by increasing policymakers' dependence on information they supplied; and (iv) provide businesses with a persuasive means of challenging potential and existing legislation. The data reveal that an ensuing lobbying campaign, largely driven by BAT, helped secure binding changes to the EU Treaty via the Treaty of Amsterdam that required EU policymakers to minimise legislative burdens on businesses. Efforts subsequently focused on ensuring that these Treaty changes were translated into the application of a business orientated form of IA (cost-benefit analysis [CBA]) within EU policymaking procedures. Both the tobacco and chemical industries have since employed IA in

  6. “Working the System”—British American Tobacco's Influence on the European Union Treaty and Its Implications for Policy: An Analysis of Internal Tobacco Industry Documents

    Science.gov (United States)

    Smith, Katherine E.; Fooks, Gary; Collin, Jeff; Weishaar, Heide; Mandal, Sema; Gilmore, Anna B.

    2010-01-01

    Background Impact assessment (IA) of all major European Union (EU) policies is now mandatory. The form of IA used has been criticised for favouring corporate interests by overemphasising economic impacts and failing to adequately assess health impacts. Our study sought to assess how, why, and in what ways corporations, and particularly the tobacco industry, influenced the EU's approach to IA. Methods and Findings In order to identify whether industry played a role in promoting this system of IA within the EU, we analysed internal documents from British American Tobacco (BAT) that were disclosed following a series of litigation cases in the United States. We combined this analysis with one of related literature and interviews with key informants. Our analysis demonstrates that from 1995 onwards BAT actively worked with other corporate actors to successfully promote a business-oriented form of IA that favoured large corporations. It appears that BAT favoured this form of IA because it could advance the company's European interests by establishing ground rules for policymaking that would: (i) provide an economic framework for evaluating all policy decisions, implicitly prioritising costs to businesses; (ii) secure early corporate involvement in policy discussions; (iii) bestow the corporate sector with a long-term advantage over other actors by increasing policymakers' dependence on information they supplied; and (iv) provide businesses with a persuasive means of challenging potential and existing legislation. The data reveal that an ensuing lobbying campaign, largely driven by BAT, helped secure binding changes to the EU Treaty via the Treaty of Amsterdam that required EU policymakers to minimise legislative burdens on businesses. Efforts subsequently focused on ensuring that these Treaty changes were translated into the application of a business orientated form of IA (cost–benefit analysis [CBA]) within EU policymaking procedures. Both the tobacco and chemical

  7. Cigarette company trade secrets are not secret: an analysis of reverse engineering reports in internal tobacco industry documents released as a result of litigation.

    Science.gov (United States)

    Velicer, Clayton; Lempert, Lauren K; Glantz, Stanton

    2015-09-01

    Use previously secret tobacco industry documents to assess tobacco companies' routine claims of trade secret protection for information on cigarette ingredients, additives and construction made to regulatory agencies, as well as the companies' refusal to publicly disclose this information. We analysed previously secret tobacco industry documents available at (http://legacy.library.ucsf.edu) to identify 100 examples of seven major tobacco companies' reverse engineering of their competitors' brands between 1937 and 2001. These reverse engineering reports contain detailed data for 142 different measurements for at least two companies, including physical parameters of the cigarettes, tobacco types, humectants, additives, flavourings, and smoke constituents of competitors' cigarettes. These 100 documents were distributed to 564 employees, including top managers in domestic and foreign offices across multiple departments, including executive leadership, research and design, product development, marketing and legal. These documents reported new competitors' products, measured ingredient changes over time, and informed companies' decisions regarding ingredients in their own products. Because cigarette companies routinely analyse their competitors' cigarettes in great detail, this information is neither secret nor commercially valuable and, thus, does not meet the legal definition of a 'trade secret.' This information is only being kept 'secret' from the people consuming cigarettes and the scientific community. Public agencies should release this detailed information because it would provide valuable information about how ingredients affect addictiveness and toxicity, and would help the public health community and consumers better understand the impact of cigarette design on human health. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  8. Technical approach document

    International Nuclear Information System (INIS)

    1989-12-01

    The Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, Public Law 95-604 (PL95-604), grants the Secretary of Energy the authority and responsibility to perform such actions as are necessary to minimize radiation health hazards and other environmental hazards caused by inactive uranium mill sites. This Technical Approach Document (TAD) describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement remedial action plans (RAPS) and final designs that comply with EPA standards. It does not address the technical approaches necessary for aquifer restoration at processing sites; a guidance document, currently in preparation, will describe aquifer restoration concerns and technical protocols. This document is a second revision to the original document issued in May 1986; the revision has been made in response to changes to the groundwater standards of 40 CFR 192, Subparts A--C, proposed by EPA as draft standards. New sections were added to define the design approaches and designs necessary to comply with the groundwater standards. These new sections are in addition to changes made throughout the document to reflect current procedures, especially in cover design, water resources protection, and alternate site selection; only minor revisions were made to some of the sections. Sections 3.0 is a new section defining the approach taken in the design of disposal cells; Section 4.0 has been revised to include design of vegetated covers; Section 8.0 discusses design approaches necessary for compliance with the groundwater standards; and Section 9.0 is a new section dealing with nonradiological hazardous constituents. 203 refs., 18 figs., 26 tabs

  9. Areva - 2011 Reference document

    International Nuclear Information System (INIS)

    2011-01-01

    After having indicated the person responsible of this document and the legal account auditors, and provided some financial information, this document gives an overview of the different risk factors existing in the company: law risks, industrial and environmental risks, operational risks, risks related to large projects, market and liquidity risks. Then, after having recalled the history and evolution of the company and the evolution of its investments over the last five years, it proposes an overview of Areva's activities on the markets of nuclear energy and renewable energies, of its clients and suppliers, of its strategy, of the activities of its different departments. Other information are provided: company's flow chart, estate properties (plants, equipment), an analysis of its financial situation, its research and development policy, the present context, profit previsions or estimations, management organization and operation

  10. Assessment of Adverse Events in Protocols, Clinical Study Reports, and Published Papers of Trials of Orlistat: A Document Analysis.

    Directory of Open Access Journals (Sweden)

    Jeppe Bennekou Schroll

    2016-08-01

    seven papers stated that "all adverse events were recorded." For one trial, we identified an additional 1,318 adverse events that were not listed or mentioned in the CSR itself but could be identified through manually counting individual adverse events reported in an appendix. We discovered that the majority of patients had multiple episodes of the same adverse event that were only counted once, though this was not described in the CSRs. We also discovered that participants treated with orlistat experienced twice as many days with adverse events as participants treated with placebo (22.7 d versus 14.9 d, p-value < 0.0001, Student's t test. Furthermore, compared with the placebo group, adverse events in the orlistat group were more severe. None of this was stated in the CSR or in the published paper. Our analysis was restricted to one drug tested in the mid-1990s; our results might therefore not be applicable for newer drugs.In the orlistat trials, we identified important disparities in the reporting of adverse events between protocols, clinical study reports, and published papers. Reports of these trials seemed to have systematically understated adverse events. Based on these findings, systematic reviews of drugs might be improved by including protocols and CSRs in addition to published articles.

  11. Document creation, linking, and maintenance system

    Science.gov (United States)

    Claghorn, Ronald [Pasco, WA

    2011-02-15

    A document creation and citation system designed to maintain a database of reference documents. The content of a selected document may be automatically scanned and indexed by the system. The selected documents may also be manually indexed by a user prior to the upload. The indexed documents may be uploaded and stored within a database for later use. The system allows a user to generate new documents by selecting content within the reference documents stored within the database and inserting the selected content into a new document. The system allows the user to customize and augment the content of the new document. The system also generates citations to the selected content retrieved from the reference documents. The citations may be inserted into the new document in the appropriate location and format, as directed by the user. The new document may be uploaded into the database and included with the other reference documents. The system also maintains the database of reference documents so that when changes are made to a reference document, the author of a document referencing the changed document will be alerted to make appropriate changes to his document. The system also allows visual comparison of documents so that the user may see differences in the text of the documents.

  12. Documenting feedbacks between surface processes and structural deformation in East Timor using stream profile and drainage network analysis

    Science.gov (United States)

    Tate, G. W.; Willett, S.; McQuarrie, N.; Goren, L.; Fox, M.

    2013-12-01

    While river profile analyses have long been used to evaluate the development of landforms, recent advances in analyzing drainage networks have significantly improved the ability to positively link stream profiles with surface uplift. In one such method, Perron and Royden (2012) define the value chi, an integral quantity based on the steady-state stream power equation which aids in determining the conformity of rivers and drainage basins to steady-state behavior. East Timor is an ideal location to test new methods using chi, as it is an active and unglaciated orogen with independent constraints of the deformational history through thermochronology and structural geology. We utilize the calculation of chi in our analyses of the drainage network to provide new constraints on the most recent uplift history of the island of Timor. Discontinuities in chi across drainage divides imply different steady state baselevel for hillslopes and therefore active migration of the divide. We confirm this by noting visible landslides in satellite images and asymmetries in hillslope steepness. Analyses of chi and elevation reveal in some locations that tributaries within a single basin have experienced distinctly different histories, documenting instances where previous river capture has occurred. In other locations the relationships between chi and elevation along single rivers denote spatial changes in surface uplift rate. Many of these observations from the drainage network correspond well to patterns of recent exhumation identified from thermochronologic analyses as well as structural constraints from field mapping and balanced cross-sections. Much of the fastest exhumation on the island (as indicated by zircon (U-Th)/He ages of 1.5-3.8 Ma and modeled exhumation rates of 1-3 mm/yr) is in the hinterland slate belt, which also contains the most stream profile remnants of paleo-capture events. Many locations of active river capture correspond well to independently constrained

  13. Document delivery services contrasting views

    CERN Document Server

    1999-01-01

    Design and maintain document delivery services that are ideal for academic patrons! In Document Delivery Services: Contrasting Views, you'll visit four university library systems to discover the considerations and challenges each library faced in bringing document delivery to its clientele. This book examines the questions about document delivery that are most pressing in the profession of library science. Despite their own unique experiences, you'll find common practices among all four?including planning, implementation of service, and evaluation of either user satisfaction and/or vendor per

  14. Document image retrieval through word shape coding.

    Science.gov (United States)

    Lu, Shijian; Li, Linlin; Tan, Chew Lim

    2008-11-01

    This paper presents a document retrieval technique that is capable of searching document images without OCR (optical character recognition). The proposed technique retrieves document images by a new word shape coding scheme, which captures the document content through annotating each word image by a word shape code. In particular, we annotate word images by using a set of topological shape features including character ascenders/descenders, character holes, and character water reservoirs. With the annotated word shape codes, document images can be retrieved by either query keywords or a query document image. Experimental results show that the proposed document image retrieval technique is fast, efficient, and tolerant to various types of document degradation.

  15. Monitored Retrievable Storage System Requirements Document

    International Nuclear Information System (INIS)

    1994-03-01

    This Monitored Retrievable Storage System Requirements Document (MRS-SRD) describes the functions to be performed and technical requirements for a Monitored Retrievable Storage (MRS) facility subelement and the On-Site Transfer and Storage (OSTS) subelement. The MRS facility subelement provides for temporary storage, at a Civilian Radioactive Waste Management System (CRWMS) operated site, of spent nuclear fuel (SNF) contained in an NRC-approved Multi-Purpose Canister (MPC) storage mode, or other NRC-approved storage modes. The OSTS subelement provides for transfer and storage, at Purchaser sites, of spent nuclear fuel (SNF) contained in MPCs. Both the MRS facility subelement and the OSTS subelement are in support of the CRWMS. The purpose of the MRS-SRD is to define the top-level requirements for the development of the MRS facility and the OSTS. These requirements include design, operation, and decommissioning requirements to the extent they impact on the physical development of the MRS facility and the OSTS. The document also presents an overall description of the MRS facility and the OSTS, their functions (derived by extending the functional analysis documented by the Physical System Requirements (PSR) Store Waste Document), their segments, and the requirements allocated to the segments. In addition, the top-level interface requirements of the MRS facility and the OSTS are included. As such, the MRS-SRD provides the technical baseline for the MRS Safety Analysis Report (SAR) design and the OSTS Safety Analysis Report design

  16. Informative document waste plastics

    NARCIS (Netherlands)

    Nagelhout D; Sein AA; Duvoort GL

    1989-01-01

    This "Informative document waste plastics" forms part of a series of "informative documents waste materials". These documents are conducted by RIVM on the indstruction of the Directorate General for the Environment, Waste Materials Directorate, in behalf of the program of

  17. Informative document packaging waste

    NARCIS (Netherlands)

    Joosten JM; Nagelhout D; Duvoort GL; Weerd M de

    1989-01-01

    This "informative document packaging waste" forms part of a series of "informative documents waste materials". These documents are conducted by RIVM on the instructions of the Direcotrate General for the Environment, Waste Materials Directorate, in behalf of the program of

  18. Contextualizing Data Warehouses with Documents

    DEFF Research Database (Denmark)

    Perez, Juan Manuel; Berlanga, Rafael; Aramburu, Maria Jose

    2008-01-01

    warehouse with a document warehouse, resulting in a contextualized warehouse. Thus, the user first selects an analysis context by supplying some keywords. Then, the analysis is performed on a novel type of OLAP cube, called an R-cube, which is materialized by retrieving and ranking the documents......Current data warehouse and OLAP technologies are applied to analyze the structured data that companies store in databases. The context that helps to understand data over time is usually described separately in text-rich documents. This paper proposes to integrate the traditional corporate data...

  19. Universidade corporativa: teoria e análise documentária | The corporative university: theory and documentary analysis

    Directory of Open Access Journals (Sweden)

    Claudio Henrique Schons

    2008-04-01

    Full Text Available Resumo O presente artigo apresenta um panorama teórico e prático sobre a Universidade Corporativa. Discute-se o papel do e-Learning e das tecnologias da informação no suporte ao processo organizacional das Universidades Corporativas. Para expor estas relações a partir da revisão da literatura, foram avaliados diversos aspectos referentes a Universidade Corporativa numa empresa multinacional para evidenciar seu valor na comunicação, construção do conhecimento e aprendizado organizacional contínuo. A metodologia utilizada baseou-se na pesquisa bibliográfica e na pesquisa documental. Como aspecto conclusivo destaca-se a importância da Universidade Corporativa como catalisadora do capital humano e intelectual, assim como também do aprendizado individual e corporativo. Palavras-chave Universidade Corporativa, e-Learning, Tecnologia da Informação.   Abstract This article presents a theoretical and practical panorama of the Corporate University. It discusses the role of e-Learning and information technology in the support of the organizational process of Corporate Universities. To explicit these relations based on a review of the literature, several aspects were considered in a multinational firm in order to highlight the importance attributed to communication, knowledge construction and continuous organizational learning. The methodology was based on the bibliographical and documentary research. In conclusion, the paper considers the importance of Corporate University as a catalyser of human and intellectual capital, as well as of individual and corporate learning. Keywords Corporate University, e-Learning, Information Technology.

  20. Generic safety documentation model

    Energy Technology Data Exchange (ETDEWEB)

    Mahn, J.A.

    1994-04-01

    This document is intended to be a resource for preparers of safety documentation for Sandia National Laboratories, New Mexico facilities. It provides standardized discussions of some topics that are generic to most, if not all, Sandia/NM facilities safety documents. The material provides a ``core`` upon which to develop facility-specific safety documentation. The use of the information in this document will reduce the cost of safety document preparation and improve consistency of information.

  1. Generic safety documentation model

    International Nuclear Information System (INIS)

    Mahn, J.A.

    1994-04-01

    This document is intended to be a resource for preparers of safety documentation for Sandia National Laboratories, New Mexico facilities. It provides standardized discussions of some topics that are generic to most, if not all, Sandia/NM facilities safety documents. The material provides a ''core'' upon which to develop facility-specific safety documentation. The use of the information in this document will reduce the cost of safety document preparation and improve consistency of information

  2. Exploiting Document Level Semantics in Document Clustering

    OpenAIRE

    Muhammad Rafi; Muhammad Naveed Sharif; Waleed Arshad; Habibullah Rafay

    2016-01-01

    Document clustering is an unsupervised machine learning method that separates a large subject heterogeneous collection (Corpus) into smaller, more manageable, subject homogeneous collections (clusters). Traditional method of document clustering works around extracting textual features like: terms, sequences, and phrases from documents. These features are independent of each other and do not cater meaning behind these word in the clustering process. In order to perform semantic viable clusteri...

  3. Validation of Chlorine and Oxygen Isotope Ratio Analysis To Differentiate Perchlorate Sources and To Document Perchlorate Biodegradation

    Science.gov (United States)

    2013-05-31

    including (1) military training, testing, and disposal activities; (2) usage and/or disposal of commercial products, including fireworks, flares...additional tables and figures cited in the paper (Tables S1-S3 and Figures S1-S6). This material is available free of charge via the Internet at http...the unsaturated zone over millennial time scales and then was flushed to groundwater as widespread irrigation became common starting in the 1930s (4

  4. Three generations of human rights of women in the 20th century : an analysis of international legal documents

    OpenAIRE

    Birdal, Sevcan

    2014-01-01

    Ankara : The Department of International Relations İhsan Doğramacı Bilkent University, 2014. Thesis (Master's) -- Bilkent University, 2014. Includes bibliographical references leaves 129-142 This thesis focuses on the generations of human rights of women based on Vasak’s notion of three generations of human rights - in which the first generation rights refer political and civil rights; the second generation rights include economic, social and cultural rights while the third ...

  5. 22 CFR 42.65 - Supporting documents.

    Science.gov (United States)

    2010-04-01

    ... or documents include any records or documents establishing the applicant's relationship to a spouse... evidence attached to the visa. (e) Authenticity of records and documents. If the consular officer has... necessary to determine its authenticity or to ascertain the facts to which the record or document purports...

  6. 40 CFR 1508.10 - Environmental document.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Environmental document. 1508.10 Section 1508.10 Protection of Environment COUNCIL ON ENVIRONMENTAL QUALITY TERMINOLOGY AND INDEX § 1508.10 Environmental document. Environmental document includes the documents specified in § 1508.9 (environmental...

  7. Evaluation, Analysis, and Documentation Support for the 10kW Signature Suppressed Lightweight Electric Energy Plant (SLEEP)

    Science.gov (United States)

    1988-03-14

    pumping losses and reduced heat transfer. Hydrogen and helium attained nearly 48% efficiency at speeds near 1300 rpm and helium gave higher power...34Molten Carbonate Fuel Cell Development And System Analysis," IECEC 󈨚 369244, 1986. Ic Tew, R.C. Jr., "Progress of Stirling Cycle Analysis and Loss ...type FUR at 4000 meters. e. Size and Weight o The weight of SLEPP will be no more than 650 lbs. o The size of SLEEP will be no more than 30 ft 3 . f

  8. DNA analysis of hair and scat collected along snow tracks to document the presence of Canada Lynx.

    Science.gov (United States)

    Kevin S. McKelvey; Jeffrey von Kienast; Keith B. Aubry; Gary M. Koehler; Bejamin T. Maletzke; John R. Squires; Edward L. Lindquist; Steve Loch; Michael K. Schwartz

    2006-01-01

    Snow tracking is often used to inventory carnivore communities, but species identification using this method can produce ambiguous and misleading results. DNA can be extracted from hair and scat samples collected from tracks made in snow. Using DNA analysis could allow positive track identification across a broad range of snow conditions, thus increasing survey...

  9. The enhanced forest inventory and analysis program of the USDA forest service: historical perspective and announcements of statistical documentation

    Science.gov (United States)

    Ronald E. McRoberts; William A. Bechtold; Paul L. Patterson; Charles T. Scott; Gregory A. Reams

    2005-01-01

    The Forest Inventory and Analysis (FIA) program of the USDA Forest Service has initiated a transition from regional, periodic inventories to an enhanced national FIA program featuring annual measurement of a proportion of plots in each state, greater national consistency, and integration with the ground sampling component of the Forest Health Monitoring (FHM) program...

  10. Early Educational Provision--Emphasised in Education Policy Reforms in Norway? An Analysis of Education Policy Documents

    Science.gov (United States)

    Bjørnsrud, Halvor; Nilsen, Sven

    2014-01-01

    The article analyses how the intentions of early provision in Norwegian schools have been expressed in the education policy reforms in Norway from the 1970s to the present day. The first area deals with the intentions that most explicitly cover early provision; prevention, early detection and intervention. The second area of analysis relates to…

  11. ICRS Recommendation Document

    DEFF Research Database (Denmark)

    Roos, Ewa M.; Engelhart, Luella; Ranstam, Jonas

    2011-01-01

    and function evaluated for validity and psychometric properties in patients with articular cartilage lesions. Results: The knee-specific instruments, titled the International Knee Documentation Committee Subjective Knee Form and the Knee injury and Osteoarthritis and Outcome Score, both fulfill the basic......, and confirmatory longitudinal studies are needed prior to recommending this scale for use in cartilage repair. Inclusion of a generic measure is feasible in cartilage repair studies and allows analysis of health-related quality of life and health economic outcomes. The Marx or Tegner Activity Rating Scales...

  12. Reactor operation environmental information document

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, L.R.; Hayes, D.W.; Hunter, C.H.; Marter, W.L.; Moyer, R.A.

    1989-12-01

    This volume is a reactor operation environmental information document for the Savannah River Plant. Topics include meteorology, surface hydrology, transport, environmental impacts, and radiation effects. 48 figs., 56 tabs. (KD)

  13. A comparative analysis of Photovoltaic Technological Innovation Systems including international dimensions: the cases of Japan and The Netherlands

    NARCIS (Netherlands)

    Vasseur, V.; Kamp, L.M.; Negro, S.O.

    2013-01-01

    This paper investigates the development and diffusion of photovoltaic (PV) technology in Japan and The Netherlands. Both cases are analysed with the Technological Innovation Systems (TIS) framework, which focuses on a particular technology and includes all those factors that influence the

  14. From Survey to FEM Analysis for Documentation of Built Heritage: the Case Study of Villa Revedin-Bolasco

    Science.gov (United States)

    Guarnieri, A.; Fissore, F.; Masiero, A.; Di Donna, A.; Coppa, U.; Vettore, A.

    2017-05-01

    In the last decade advances in the fields of close-range photogrammetry, terrestrial laser scanning (TLS) and computer vision (CV) have enabled to collect different kind of information about a Cultural Heritage objects and to carry out highly accurate 3D models. Additionally, the integration between laser scanning technology and Finite Element Analysis (FEA) is gaining particular interest in recent years for structural analysis of built heritage, since the increasing computational capabilities allow to manipulate large datasets. In this note we illustrate the approach adopted for surveying, 3D modeling and structural analysis of Villa Revedin-Bolasco, a magnificent historical building located in the small walled town of Castelfranco Veneto, in northern Italy. In 2012 CIRGEO was charged by the University of Padova to carry out a survey of the Villa and Park, as preliminary step for subsequent restoration works. The inner geometry of the Villa was captured with two Leica Disto D3a BT hand-held laser meters, while the outer walls of the building were surveyed with a Leica C10 and a Faro Focus 3D 120 terrestrial laser scanners. Ancillary GNSS measurements were also collected for 3D laser model georeferencing. A solid model was then generated from the laser global point cloud in Rhinoceros software, and portion of it was used for simulation in a Finite Element Analysis (FEA). In the paper we discuss in detail all the steps and challenges addressed and solutions adopted concerning the survey, solid modeling and FEA from laser scanning data of the historical complex of Villa Revedin-Bolasco.

  15. ICECON: a computer program used to calculate containment back pressure for LOCA analysis (including ice condenser plants)

    International Nuclear Information System (INIS)

    1976-07-01

    The ICECON computer code provides a method for conservatively calculating the long term back pressure transient in the containment resulting from a hypothetical Loss-of-Coolant Accident (LOCA) for PWR plants including ice condenser containment systems. The ICECON computer code was developed from the CONTEMPT/LT-022 code. A brief discussion of the salient features of a typical ice condenser containment is presented. Details of the ice condenser models are explained. The corrections and improvements made to CONTEMPT/LT-022 are included. The organization of the code, including the calculational procedure, is outlined. The user's manual, to be used in conjunction with the CONTEMPT/LT-022 user's manual, a sample problem, a time-step study (solution convergence) and a comparison of ICECON results with the results of the NSSS vendor are presented. In general, containment pressure calculated with the ICECON code agree with those calculated by the NSSS vendor using the same mass and energy release rates to the containment

  16. Structural Classification for Retrospective Conversion of Documents

    OpenAIRE

    Héroux, Pierre; Trupin, Eric; Lecourtier, Yves

    2000-01-01

    International audience; This paper describes the structural classification method used in a strategy for retrospective conversion of documents. This strategy consists in an cycle in which document analysis and document understanding interact. This cycle is initialized by the extraction of the outline of the layout and logical structures of the document. Then, each iteration of the cycle consists in the detection and the processing of inconsistencies in the document modeling. The cycle ends wh...

  17. Metal load assessment in patient pulmonary lavages: towards a comprehensive mineralogical analysis including the nano-sized fraction.

    Science.gov (United States)

    Forest, Valérie; Vergnon, Jean-Michel; Guibert, Cyril; Bitounis, Dimitrios; Leclerc, Lara; Sarry, Gwendoline; Pourchez, Jérémie

    Mineralogical analyses of clinical samples have been proved useful to identify causal relationship between exposure to airborne particles and pulmonary diseases. The most striking example is asbestosis where the assessment of asbestos bodies in patient lung samples has allowed defining values specific of pathologies. However, this type of analyses only considers the micro-sized fraction of the particles, neglecting the specific impact of nano-sized particles which have been otherwise shown to be reactive and able to induce biological effects. Similarly, in nanotoxicology, the mineralogical analysis of pulmonary fluids could be used as an indicator of exposure to inhaled nanoparticles and could help investigations on the relationship between exposure to these nanoparticles and lung diseases. We designed this study first to demonstrate the technical feasibility of this approach, then to get a clear picture of the metals present, and in what form, in patient lungs and finally to determine if indeed it is worth investigating separately the micro, sub-micro and nano fractions. Broncho-alveolar lavages were recovered from 100 patients suffering from interstitial lung diseases. A protocol was specifically developed to isolate three fractions containing respectively microparticles, sub-microparticles and nanoparticles with ions. The metal content in each fraction was qualitatively and quantitatively characterized. Results showed significant differences between the three fractions in terms of metal load confirming that the separate analysis of the fractions is relevant. It also means that the assessment of the micro-sized fraction alone, as commonly done in clinical practice, only gives a partial view of the mineralogical analysis.

  18. The Prognostic Significance of Pretreatment Serum CEA Levels in Gastric Cancer: A Meta-Analysis Including 14651 Patients

    Science.gov (United States)

    Deng, Kai; Yang, Li; Hu, Bing; Wu, Hao; Zhu, Hong; Tang, Chengwei

    2015-01-01

    Background Carcinoembryonic antigen (CEA) is commonly used as a serum tumor marker in clinical practice; however, its prognostic value for gastric cancer patients remains uncertain. This meta-analysis was performed to assess the prognostic value of CEA and investigate CEA as a tumor marker. Methods PubMed, EMBASE and other databases were searched for potentially eligible studies. Forty-one studies reporting the prognostic effect of pretreatment serum CEA expression in gastric cancer patients were selected. Data on 14651 eligible patients were retrieved for the meta-analysis. Based on the data extracted from the available literature, the hazard ratio (HR) and 95% confidence interval (CI) for an adverse prognosis were estimated for gastric cancer patients with elevated pretreatment serum levels of CEA (CEA+) relative to patients with normal pretreatment CEA levels (CEA-). Results The CEA+ patients had a significantly poorer prognosis than the CEA- patients in terms of overall survival (OS: HR 1.716, 95% CI 1.594 - 1.848, P 0.05). In the pooled analyses of multivariate-adjusted HRs, the results suggested that pretreatment serum CEA may be an independent prognostic factor in gastric cancer (OS: HR 1.681, 95% CI 1.425 - 1.982; DSS: HR 1.900, 95% CI 1.441 - 2.505; DFS: HR 2.579, 95% CI 1.935 - 3.436). Conclusion/Significance The meta-analysis based on the available literature supported the association of elevated pretreatment serum CEA levels with a poor prognosis for gastric cancer and a nearly doubled risk of mortality in gastric cancer patients. CEA may be an independent prognostic factor for gastric cancer patients and may aid in determining appropriate treatment which may preferentially benefit the CEA+ patients. PMID:25879931

  19. Extended automated separation techniques in destructive neutron activation analysis; application to various biological materials, including human tissues and blood

    International Nuclear Information System (INIS)

    Tjioe, P.S.; Goeij, J.J.M. de; Houtman, J.P.W.

    1976-09-01

    Neutron activation analysis may be performed as a multi-element and low-level technique for many important trace elements in biological materials, provided that post-irradiation chemical separations are applied. This paper describes a chemical separation consisting of automated procedures for destruction, distillation, and anion-chromatography. The system developed enables the determination of 14 trace elements in biological materials, viz. antimony, arsenic, bromine, cadmium, chromium, cobalt, copper, gold, iron, mercury, molybdenum, nickel, selenium, and zinc. The aspects of sample preparation, neutron irradiation, gamma-spectrum evaluation, and blank-value contribution are also discussed

  20. The Algorithm Theoretical Basis Document for the Derivation of Range and Range Distributions from Laser Pulse Waveform Analysis for Surface Elevations, Roughness, Slope, and Vegetation Heights

    Science.gov (United States)

    Brenner, Anita C.; Zwally, H. Jay; Bentley, Charles R.; Csatho, Bea M.; Harding, David J.; Hofton, Michelle A.; Minster, Jean-Bernard; Roberts, LeeAnne; Saba, Jack L.; Thomas, Robert H.; hide

    2012-01-01

    The primary purpose of the GLAS instrument is to detect ice elevation changes over time which are used to derive changes in ice volume. Other objectives include measuring sea ice freeboard, ocean and land surface elevation, surface roughness, and canopy heights over land. This Algorithm Theoretical Basis Document (ATBD) describes the theory and implementation behind the algorithms used to produce the level 1B products for waveform parameters and global elevation and the level 2 products that are specific to ice sheet, sea ice, land, and ocean elevations respectively. These output products, are defined in detail along with the associated quality, and the constraints, and assumptions used to derive them.

  1. Biomechanical analysis of a salt-modified polyvinyl alcohol hydrogel for knee meniscus applications, including comparison with human donor samples.

    Science.gov (United States)

    Hayes, Jennifer C; Curley, Colin; Tierney, Paul; Kennedy, James E

    2016-03-01

    The primary objective of this research was the biomechanical analysis of a salt-modified polyvinyl alcohol hydrogel, in order to assess its potential for use as an artificial meniscal implant. Aqueous polyvinyl alcohol (PVA) was treated with a sodium sulphate (Na2SO4) solution to precipitate out the polyvinyl alcohol resulting in a pliable hydrogel. The freeze-thaw process, a strictly physical method of crosslinking, was employed to crosslink the hydrogel. Development of a meniscal shaped mould and sample housing unit allowed the production of meniscal shaped hydrogels for direct comparison to human meniscal tissue. Results obtained show that compressive responses were slightly higher in PVA/Na2SO4 menisci, displaying maximum compressive loads of 2472N, 2482N and 2476N for samples having undergone 1, 3 and 5 freeze-thaw cycles respectively. When compared to the human meniscal tissue tested under the same conditions, an average maximum load of 2467.5N was observed. This suggests that the PVA/Na2SO4 menisci are mechanically comparable to the human meniscus. Biocompatibility analysis of PVA/Na2SO4 hydrogels revealed no acute cytotoxicity. The work described herein has innovative potential in load bearing applications, specifically as an alternative to meniscectomy as replacement of critically damaged meniscal tissue in the knee joint where repair is not viable. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Prostitution Policies in Switzerland and the City of Zurich: A Critical Frame Analysis of Official Documents and NGO Papers

    OpenAIRE

    Isler, Corinne

    2016-01-01

    The phenomenon of prostitution has been controversial in many countries, including Switzerland. Policy regimes on prostitution differ drastically between countries. In recent years, there have been two opposing trends regarding the reform of prostitution laws. Some countries, such as Germany and the Netherlands, have moved towards legalisation and normalisation of the sex industry. Prostitution is thereby regarded as a normal trade and feminist supporters of this model focus mainly on legal r...

  3. Cognitive Temporal Document Priors

    NARCIS (Netherlands)

    Peetz, M.H.; de Rijke, M.

    2013-01-01

    Temporal information retrieval exploits temporal features of document collections and queries. Temporal document priors are used to adjust the score of a document based on its publication time. We consider a class of temporal document priors that is inspired by retention functions considered in

  4. Building documentation generators

    NARCIS (Netherlands)

    A. van Deursen (Arie); T. Kuipers (Tobias)

    1999-01-01

    textabstractIn order to maintain the consistency between sources and documentation, while at the same time providing documentation at the design level, it is necessary to generate documentation from sources in such a way that it can be integrated with hand-written documentation. In order to

  5. Analysis of Two Stroke Marine Diesel Engine Operation Including Turbocharger Cut-Out by Using a Zero-Dimensional Model

    Directory of Open Access Journals (Sweden)

    Cong Guan

    2015-06-01

    Full Text Available In this article, the operation of a large two-stroke marine diesel engine including various cases with turbocharger cut-out was thoroughly investigated by using a modular zero-dimensional engine model built in MATLAB/Simulink environment. The model was developed by using as a basis an in-house modular mean value engine model, in which the existing cylinder block was replaced by a more detailed one that is capable of representing the scavenging ports-cylinder-exhaust valve processes. Simulation of the engine operation at steady state conditions was performed and the derived engine performance parameters were compared with the respective values obtained by the engine shop trials. The investigation of engine operation under turbocharger cut-out conditions in the region from 10% to 50% load was carried out and the influence of turbocharger cut-out on engine performance including the in-cylinder parameters was comprehensively studied. The recommended schedule for the combination of the turbocharger cut-out and blower activation was discussed for the engine operation under part load conditions. Finally, the influence of engine operating strategies on the annual fuel savings, CO2 emissions reduction and blower operating hours for a Panamax container ship operating at slow steaming conditions is presented and discussed.

  6. Domestic violence documentation project 2012.

    Science.gov (United States)

    Nittis, Maria; Hughes, Rod; Gray, Cecile; Ashton, Mandy

    2013-08-01

    One in four women presenting to Emergency Departments in Australia have experienced domestic violence in their lives but there are no specialist services for victims of domestic violence in the state of New South Wales, population of 7.25 million. Fundamental forensic medical and nursing skills developed for the comprehensive assessment of complainants of sexual assault were utilised in the examination of victims of domestic violence in a trial project at Nepean Hospital, Sydney. The project was then reviewed via a series of qualitative patient and police interviews along with an analysis of court outcomes. Assessment by specialists in forensic documentation and interpretation of injuries with the provision of balanced expert opinions for court purposes can result in a number of benefits for the victims and the criminal justice system, including an increase in the rate of successful prosecutions. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  7. Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis.

    Science.gov (United States)

    Ford, Alexander C; Quigley, Eamonn M M; Lacy, Brian E; Lembo, Anthony J; Saito, Yuri A; Schiller, Lawrence R; Soffer, Edy E; Spiegel, Brennan M R; Moayyedi, Paul

    2014-09-01

    Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder. Evidence relating to the treatment of this condition with antidepressants and psychological therapies continues to accumulate. We performed an updated systematic review and meta-analysis of randomized controlled trials (RCTs). MEDLINE, EMBASE, and the Cochrane Controlled Trials Register were searched (up to December 2013). Trials recruiting adults with IBS, which compared antidepressants with placebo, or psychological therapies with control therapy or "usual management," were eligible. Dichotomous symptom data were pooled to obtain a relative risk (RR) of remaining symptomatic after therapy, with a 95% confidence interval (CI). The search strategy identified 3,788 citations. Forty-eight RCTs were eligible for inclusion: thirty-one compared psychological therapies with control therapy or "usual management," sixteen compared antidepressants with placebo, and one compared both psychological therapy and antidepressants with placebo. Ten of the trials of psychological therapies, and four of the RCTs of antidepressants, had been published since our previous meta-analysis. The RR of IBS symptom not improving with antidepressants vs. placebo was 0.67 (95% CI=0.58-0.77), with similar treatment effects for both tricyclic antidepressants and selective serotonin reuptake inhibitors. The RR of symptoms not improving with psychological therapies was 0.68 (95% CI=0.61-0.76). Cognitive behavioral therapy, hypnotherapy, multicomponent psychological therapy, and dynamic psychotherapy were all beneficial. Antidepressants and some psychological therapies are effective treatments for IBS. Despite the considerable number of studies published in the intervening 5 years since we last examined this issue, the overall summary estimates of treatment effect have remained remarkably stable.

  8. Comparative genomic analysis of the genus Staphylococcus including Staphylococcus aureus and its newly described sister species Staphylococcus simiae

    Science.gov (United States)

    2012-01-01

    Background Staphylococcus belongs to the Gram-positive low G + C content group of the Firmicutes division of bacteria. Staphylococcus aureus is an important human and veterinary pathogen that causes a broad spectrum of diseases, and has developed important multidrug resistant forms such as methicillin-resistant S. aureus (MRSA). Staphylococcus simiae was isolated from South American squirrel monkeys in 2000, and is a coagulase-negative bacterium, closely related, and possibly the sister group, to S. aureus. Comparative genomic analyses of closely related bacteria with different phenotypes can provide information relevant to understanding adaptation to host environment and mechanisms of pathogenicity. Results We determined a Roche/454 draft genome sequence for S. simiae and included it in comparative genomic analyses with 11 other Staphylococcus species including S. aureus. A genome based phylogeny of the genus confirms that S. simiae is the sister group to S. aureus and indicates that the most basal Staphylococcus lineage is Staphylococcus pseudintermedius, followed by Staphylococcus carnosus. Given the primary niche of these two latter taxa, compared to the other species in the genus, this phylogeny suggests that human adaptation evolved after the split of S. carnosus. The two coagulase-positive species (S. aureus and S. pseudintermedius) are not phylogenetically closest but share many virulence factors exclusively, suggesting that these genes were acquired by horizontal transfer. Enrichment in genes related to mobile elements such as prophage in S. aureus relative to S. simiae suggests that pathogenesis in the S. aureus group has developed by gene gain through horizontal transfer, after the split of S. aureus and S. simiae from their common ancestor. Conclusions Comparative genomic analyses across 12 Staphylococcus species provide hypotheses about lineages in which human adaptation has taken place and contributions of horizontal transfer in pathogenesis. PMID

  9. Direct Analysis as a historical documentation tool of the remains of the Castielfabib ramparts and their evolution (Valencian Community, Spain

    Directory of Open Access Journals (Sweden)

    Álvaro Vázquez Esparza

    2017-12-01

    Full Text Available   Castielfabib is a small town on the frontier between the old Spanish kingdoms of Castilla and Aragon. Due to the fact that the few remaining segments of its old walls are widely separated from each other, it is not possible to establish with any certainty a plan of the original ramparts. There is also the added complication of the wide variety of materials of which the different segments are composed, which makes it difficult to date or establish relationships between them. This meant that direct analysis of the masonry and paraments by digital tools was the only practical method of obtaining scientific data on the evolution of the different remains as a basis for forming sound hypotheses on their construction and evolution.

  10. Tobacco company efforts to influence the Food and Drug Administration-commissioned Institute of Medicine report clearing the smoke: an analysis of documents released through litigation.

    Directory of Open Access Journals (Sweden)

    Crystal E Tan

    Full Text Available Spurred by the creation of potential modified risk tobacco products, the US Food and Drug Administration (FDA commissioned the Institute of Medicine (IOM to assess the science base for tobacco "harm reduction," leading to the 2001 IOM report Clearing the Smoke. The objective of this study was to determine how the tobacco industry organized to try to influence the IOM committee that prepared the report.We analyzed previously secret tobacco industry documents in the University of California, San Francisco Legacy Tobacco Documents Library, and IOM public access files. (A limitation of this method includes the fact that the tobacco companies have withheld some possibly relevant documents. Tobacco companies considered the IOM report to have high-stakes regulatory implications. They developed and implemented strategies with consulting and legal firms to access the IOM proceedings. When the IOM study staff invited the companies to provide information on exposure and disease markers, clinical trial design for safety and efficacy, and implications for initiation and cessation, tobacco company lawyers, consultants, and in-house regulatory staff shaped presentations from company scientists. Although the available evidence does not permit drawing cause-and-effect conclusions, and the IOM may have come to the same conclusions without the influence of the tobacco industry, the companies were pleased with the final report, particularly the recommendations for a tiered claims system (with separate tiers for exposure and risk, which they believed would ease the process of qualifying for a claim and license to sell products comparable to existing conventional cigarettes ("substantial equivalence" without prior regulatory approval. Some principles from the IOM report, including elements of the substantial equivalence recommendation, appear in the 2009 Family Smoking Prevention and Tobacco Control Act.Tobacco companies strategically interacted with the IOM to win

  11. Tobacco Company Efforts to Influence the Food and Drug Administration-Commissioned Institute of Medicine Report Clearing the Smoke: An Analysis of Documents Released through Litigation

    Science.gov (United States)

    Tan, Crystal E.; Kyriss, Thomas; Glantz, Stanton A.

    2013-01-01

    Background Spurred by the creation of potential modified risk tobacco products, the US Food and Drug Administration (FDA) commissioned the Institute of Medicine (IOM) to assess the science base for tobacco “harm reduction,” leading to the 2001 IOM report Clearing the Smoke. The objective of this study was to determine how the tobacco industry organized to try to influence the IOM committee that prepared the report. Methods and Findings We analyzed previously secret tobacco industry documents in the University of California, San Francisco Legacy Tobacco Documents Library, and IOM public access files. (A limitation of this method includes the fact that the tobacco companies have withheld some possibly relevant documents.) Tobacco companies considered the IOM report to have high-stakes regulatory implications. They developed and implemented strategies with consulting and legal firms to access the IOM proceedings. When the IOM study staff invited the companies to provide information on exposure and disease markers, clinical trial design for safety and efficacy, and implications for initiation and cessation, tobacco company lawyers, consultants, and in-house regulatory staff shaped presentations from company scientists. Although the available evidence does not permit drawing cause-and-effect conclusions, and the IOM may have come to the same conclusions without the influence of the tobacco industry, the companies were pleased with the final report, particularly the recommendations for a tiered claims system (with separate tiers for exposure and risk, which they believed would ease the process of qualifying for a claim) and license to sell products comparable to existing conventional cigarettes (“substantial equivalence”) without prior regulatory approval. Some principles from the IOM report, including elements of the substantial equivalence recommendation, appear in the 2009 Family Smoking Prevention and Tobacco Control Act. Conclusions Tobacco companies

  12. Documenting research with transgender and gender diverse people: protocol for an evidence map and thematic analysis

    Directory of Open Access Journals (Sweden)

    Zack Marshall

    2017-02-01

    Full Text Available Abstract Background There is limited information about how transgender, gender diverse, and Two-Spirit (trans people have been represented and studied by researchers. The objectives of this study are to (1 map and describe trans research in the social sciences, sciences, humanities, health, education, and business, (2 identify evidence gaps and opportunities for more responsible research with trans people, (3 assess the use of text mining for study identification, and (4 increase access to trans research for key stakeholders through the creation of a web-based evidence map. Methods Study design was informed by community consultations and pilot searches. Eligibility criteria were established to include all original research of any design, including trans people or their health information, and published in English in peer-reviewed journals. A complex electronic search strategy based on relevant concepts in 15 databases was developed to obtain a broad range of results linked to transgender, gender diverse, and Two-Spirit individuals and communities. Searches conducted in early 2015 resulted in 25,242 references after removal of duplicates. Based on the number of references, resources, and an objective to capture upwards of 90% of the existing literature, this study is a good candidate for text mining using Latent Dirichlet Allocation to improve efficiency of the screening process. The following information will be collected for evidence mapping: study topic, study design, methods and data sources, recruitment strategies, sample size, sample demographics, researcher name and affiliation, country where research was conducted, funding source, and year of publication. Discussion The proposed research incorporates an extensive search strategy, text mining, and evidence map; it therefore has the potential to build on knowledge in several fields. Review results will increase awareness of existing trans research, identify evidence gaps, and inform

  13. Documenting research with transgender and gender diverse people: protocol for an evidence map and thematic analysis.

    Science.gov (United States)

    Marshall, Zack; Welch, Vivian; Thomas, James; Brunger, Fern; Swab, Michelle; Shemilt, Ian; Kaposy, Chris

    2017-02-20

    There is limited information about how transgender, gender diverse, and Two-Spirit (trans) people have been represented and studied by researchers. The objectives of this study are to (1) map and describe trans research in the social sciences, sciences, humanities, health, education, and business, (2) identify evidence gaps and opportunities for more responsible research with trans people, (3) assess the use of text mining for study identification, and (4) increase access to trans research for key stakeholders through the creation of a web-based evidence map. Study design was informed by community consultations and pilot searches. Eligibility criteria were established to include all original research of any design, including trans people or their health information, and published in English in peer-reviewed journals. A complex electronic search strategy based on relevant concepts in 15 databases was developed to obtain a broad range of results linked to transgender, gender diverse, and Two-Spirit individuals and communities. Searches conducted in early 2015 resulted in 25,242 references after removal of duplicates. Based on the number of references, resources, and an objective to capture upwards of 90% of the existing literature, this study is a good candidate for text mining using Latent Dirichlet Allocation to improve efficiency of the screening process. The following information will be collected for evidence mapping: study topic, study design, methods and data sources, recruitment strategies, sample size, sample demographics, researcher name and affiliation, country where research was conducted, funding source, and year of publication. The proposed research incorporates an extensive search strategy, text mining, and evidence map; it therefore has the potential to build on knowledge in several fields. Review results will increase awareness of existing trans research, identify evidence gaps, and inform strategic research prioritization. Publishing the map

  14. Analysis of quantum ballistic electron transport in ultrasmall silicon devices including space-charge and geometric effects

    Science.gov (United States)

    Laux, S. E.; Kumar, A.; Fischetti, M. V.

    2004-05-01

    A two-dimensional device simulation program which self consistently solves the Schrödinger and Poisson equations with current flow is described in detail. Significant approximations adopted in this work are the absence of scattering and a simple six-valley, parabolic band structure for silicon. A modified version of the quantum transmitting boundary method is used to describe open boundary conditions permitting current flow in device solutions far from equilibrium. The continuous energy spectrum of the system is discretized by temporarily imposing two different forms of closed boundary conditions, resulting in energies which sample the density-of-states and establish the wave function normalization conditions. These standing wave solutions ("normal modes") are decomposed into their traveling wave constituents, each of which represents injection from only one of the open boundary contacts ("traveling eigencomponents"). These current-carrying states are occupied by a drifted Fermi distribution associated with their injecting contact and summed to form the electron density in the device. Holes are neglected in this calculation. The Poisson equation is solved on the same finite element computational mesh as the Schrödinger equation; devices of arbitrary geometry can be modeled. Computational performance of the program including characterization of a "Broyden+Newton" algorithm employed in the iteration for self consistency is described. Device results are presented for a narrow silicon resonant tunneling diode (RTD) and many variants of idealized silicon double-gate field effect transistors (DGFETs). The RTD results show two resonant conduction peaks, each of which demonstrates hysteresis. Three 7.5 nm channel length DGFET structures with identical intrinsic device configurations but differing access geometries (straight, taper and "dog bone") are studied and found to have differing current flows owing to quantum-mechanical reflection in their access regions

  15. Document Delivery: Evaluating the Options.

    Science.gov (United States)

    Ward, Suzanne M.

    1997-01-01

    Discusses options available to libraries for document delivery. Topics include users' needs; cost; copyright compliance; traditional interlibrary loan; types of suppliers; selection criteria, including customer service; new developments in interlibrary loan, including outsourcing arrangements; and the need to evaluate suppliers. (LRW)

  16. [Video documentation in forensic practice].

    Science.gov (United States)

    Schyma, C; Schyma, P

    1995-01-01

    The authors report in part 1 about their experiences with the Canon Ex1 Hi camcorder and the possibilities of documentation with the modern video technique. Application examples in legal medicine and criminalistics are described autopsy, scene, reconstruction of crimes etc. The online video documentation of microscopic sessions makes the discussion of findings easier. The use of video films for instruction produces a good resonance. The use of the video documentation can be extended by digitizing (Part 2). Two frame grabbers are presented, with which we obtained good results in digitizing of images captured from video. The best quality of images is achieved by online use of an image analysis chain. Corel 5.0 and PicEd Cora 4.0 allow complete image processings and analysis. The digital image processing influences the objectivity of the documentation. The applicabilities of image libraries are discussed.

  17. Analysis of scientific papers included in the sciences citation index expanded written by South korean plastic surgeons: 2001-2010.

    Science.gov (United States)

    Go, Ju Young; Mun, Goo-Hyun; Jeon, Byung-Joon; Lim, So-Young; Pyon, Jai-Kyong; Bang, Sa-Ik; Oh, Kap Sung; Shin, Myoung-Soo

    2012-01-01

    The purpose of our study was to analyze scientific papers published by South Korean plastic surgeons in journals included in the Science Citation Index Expanded (SCIE), and to evaluate the publication and research activities of Korean plastic surgeon. We conducted a survey of SCIE papers in the field of plastic surgery published by South Korean authors between 2001 and 2010 using Web of Science software. We further analyzed these results according to the number of publications per year, journals, institution, and type of papers. We also compared the total number of citations to published scientific papers. We analyzed the rank of South Korea among other countries in representative journals. Overall, 667 papers were published by South Korean authors between 2001 and 2010. The number of publications increased dramatically from 2003 (n=31) to 2010 (n=139). Subsequently, the ten most productive Korean medical colleges were identified. All published papers received 2,311 citations and the citation to paper ratio was 3.49. The rank of Korea among other countries in terms of the number of published papers remained in the top 10 during the recent 10 years. Publication output of Korean plastic surgeon over the last 10 years showed a remarkable growth in terms of quantity and quality. Currently, Korea is among the top six countries in representative plastic surgery journals. Korean plastic surgeons have played a central role in this progress, and it is anticipated that they will continue to do so in the future.

  18. Performance Analysis of a Six-Port Receiver in a WCDMA Communication System including a Multipath Fading Channel

    Directory of Open Access Journals (Sweden)

    A. O. Olopade

    2014-01-01

    Full Text Available Third generation communication systems require receivers with wide bandwidth of operation to support high transmission rates and are also reconfigurable to support various communication standards with different frequency bands. An ideal software defined radio (SDR will be the absolute answer to this requirement but it is not achievable with the current level of technology. This paper proposes the use of a six-port receiver (SPR front-end (FE in a WCDMA communication system. A WCDMA end-to-end physical layer MATLAB demo which includes a multipath channel distortion block is used to determine the viability of the six-port based receiver. The WCDMA signal after passing through a multipath channel is received using a constructed SPR FE. The baseband signal is then calibrated and corrected in MATLAB. The six-port receiver performance is measured in terms of bit error rate (BER. The signal-to-noise ratio (SNR of the transmitted IQ data is varied and the BER profile of the communication system is plotted. The effect of the multipath fading on the receiver performance and the accuracy of the calibration algorithm are obtained by comparing two different measured BER curves for different calibration techniques to the simulated BER curve of an ideal receiver.

  19. Analysis of the chromosome X exome in patients with autism spectrum disorders identified novel candidate genes, including TMLHE

    Science.gov (United States)

    Nava, C; Lamari, F; Héron, D; Mignot, C; Rastetter, A; Keren, B; Cohen, D; Faudet, A; Bouteiller, D; Gilleron, M; Jacquette, A; Whalen, S; Afenjar, A; Périsse, D; Laurent, C; Dupuits, C; Gautier, C; Gérard, M; Huguet, G; Caillet, S; Leheup, B; Leboyer, M; Gillberg, C; Delorme, R; Bourgeron, T; Brice, A; Depienne, C

    2012-01-01

    The striking excess of affected males in autism spectrum disorders (ASD) suggests that genes located on chromosome X contribute to the etiology of these disorders. To identify new X-linked genes associated with ASD, we analyzed the entire chromosome X exome by next-generation sequencing in 12 unrelated families with two affected males. Thirty-six possibly deleterious variants in 33 candidate genes were found, including PHF8 and HUWE1, previously implicated in intellectual disability (ID). A nonsense mutation in TMLHE, which encodes the ɛ-N-trimethyllysine hydroxylase catalyzing the first step of carnitine biosynthesis, was identified in two brothers with autism and ID. By screening the TMLHE coding sequence in 501 male patients with ASD, we identified two additional missense substitutions not found in controls and not reported in databases. Functional analyses confirmed that the mutations were associated with a loss-of-function and led to an increase in trimethyllysine, the precursor of carnitine biosynthesis, in the plasma of patients. This study supports the hypothesis that rare variants on the X chromosome are involved in the etiology of ASD and contribute to the sex-ratio disequilibrium. PMID:23092983

  20. Static response of coated microbubbles compressed between rigid plates: Simulations and asymptotic analysis including elastic and adhesive forces

    Science.gov (United States)

    Lytra, A.; Pelekasis, N.

    2018-03-01

    The static response of coated microbubbles is investigated with a novel approach employed for modeling contact between a microbubble and the cantilever of an atomic force microscope. Elastic tensions and moments are described via appropriate constitutive laws. The encapsulated gas is assumed to undergo isothermal variations. Due to the hydrophilic nature of the cantilever, an ultrathin aqueous film is formed, which transfers the force onto the shell. An interaction potential describes the local pressure applied on the shell. The problem is solved in axisymmetric form with the finite element method. The response is governed by the dimensionless bending, k^ b=kb/(χ R02 ), pressure, P^ A=(PAR0 )/χ , and interaction potential, W ^ =w0/χ . Hard polymeric shells have negligible resistance to gas compression, while for the softer lipid shells gas compressibility is comparable with shell elasticity. As the external force increases, numerical simulations reveal that the force versus deformation (f vs d) curve of polymeric shells exhibits a transition from the linear O(d) (Reissner) regime, marked by flattened shapes around the contact region, to a non-linear O(d1/2) (Pogorelov) regime dominated by shapes exhibiting crater formation due to buckling. When lipid shells are tested, buckling is bypassed as the external force increases and flattened shapes prevail in an initially linear f vs d curve. Transition to a curved upwards regime is observed as the force increases, where gas compression and area dilatation form the dominant balance providing a nonlinear regime with an O(d3) dependence. Asymptotic analysis recovers the above patterns and facilitates estimation of the shell mechanical properties.

  1. The Use of Speech Technology to Protect the Document Turnover

    Directory of Open Access Journals (Sweden)

    Alexandr M. Alyushin

    2017-06-01

    Full Text Available The wide current paper documents implementation in practice workflows are shown. The basic aspects of document protection related to the protection of their content and legal components are underlined. For contextual component assigned semantic information aspect of the document is considered. For legal component attributed facts and conditions for the creation, approval, negotiation of the document to specific persons is viewed. The documents protection problem importance is shown in connection with possible terrorist threats. The importance of such factor as the time of fraud detection towards the efficiency of documents protection is shown. The fraud detection time requirements for documents of different nature – financial, legal, management is analyzed. The documents used for the operational management of dangerous objects is point out as the most sensitive to the falsification. It is shown that their deliberate falsification can lead to accidents and technogenic catastrophes and human casualties. A comparative analysis of currently used protecting documents methods are presented. Biometric and non-biometric methods of documents protection are point out.Theanalysis of their short comings are given. The conclusion about the prospects of document protection on the basis of the voice signature technology are done. The basic steps of voice information processing in the implementation of this technology are analyzed. The software that implements a documents counterfeiting new protection technology is proposed. The technology is based on the audiomarkers usage at the end of the document, which contains a general information about it. The technology is applicable to the wide range of documents such as financial and valuable papers, contracts, etc. One of the most important advantages of this technology is that any changes in the document can not be done without the author of the document because audiomarker keeps the biometric data of the person

  2. LDRD 149045 final report distinguishing documents.

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Scott A.

    2010-09-01

    This LDRD 149045 final report describes work that Sandians Scott A. Mitchell, Randall Laviolette, Shawn Martin, Warren Davis, Cindy Philips and Danny Dunlavy performed in 2010. Prof. Afra Zomorodian provided insight. This was a small late-start LDRD. Several other ongoing efforts were leveraged, including the Networks Grand Challenge LDRD, and the Computational Topology CSRF project, and the some of the leveraged work is described here. We proposed a sentence mining technique that exploited both the distribution and the order of parts-of-speech (POS) in sentences in English language documents. The ultimate goal was to be able to discover 'call-to-action' framing documents hidden within a corpus of mostly expository documents, even if the documents were all on the same topic and used the same vocabulary. Using POS was novel. We also took a novel approach to analyzing POS. We used the hypothesis that English follows a dynamical system and the POS are trajectories from one state to another. We analyzed the sequences of POS using support vector machines and the cycles of POS using computational homology. We discovered that the POS were a very weak signal and did not support our hypothesis well. Our original goal appeared to be unobtainable with our original approach. We turned our attention to study an aspect of a more traditional approach to distinguishing documents. Latent Dirichlet Allocation (LDA) turns documents into bags-of-words then into mixture-model points. A distance function is used to cluster groups of points to discover relatedness between documents. We performed a geometric and algebraic analysis of the most popular distance functions and made some significant and surprising discoveries, described in a separate technical report.

  3. Registration document 2005; Document de reference 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This reference document of Gaz de France provides information and data on the Group activities in 2005: financial informations, business, activities, equipments factories and real estate, trade, capital, organization charts, employment, contracts and research programs. (A.L.B.)

  4. One Dimensional Analysis Model of a Condensing Spray Chamber Including Rocket Exhaust Using SINDA/FLUINT and CEA

    Science.gov (United States)

    Sakowski, Barbara; Edwards, Daryl; Dickens, Kevin

    2014-01-01

    Modeling droplet condensation via CFD codes can be very tedious, time consuming, and inaccurate. CFD codes may be tedious and time consuming in terms of using Lagrangian particle tracking approaches or particle sizing bins. Also since many codes ignore conduction through the droplet and or the degradating effect of heat and mass transfer if noncondensible species are present, the solutions may be inaccurate. The modeling of a condensing spray chamber where the significant size of the water droplets and the time and distance these droplets take to fall, can make the effect of droplet conduction a physical factor that needs to be considered in the model. Furthermore the presence of even a relatively small amount of noncondensible has been shown to reduce the amount of condensation [Ref 1]. It is desirable then to create a modeling tool that addresses these issues. The path taken to create such a tool is illustrated. The application of this tool and subsequent results are based on the spray chamber in the Spacecraft Propulsion Research Facility (B2) located at NASA's Plum Brook Station that tested an RL-10 engine. The platform upon which the condensation physics is modeled is SINDAFLUINT. The use of SINDAFLUINT enables the ability to model various aspects of the entire testing facility, including the rocket exhaust duct flow and heat transfer to the exhaust duct wall. The ejector pumping system of the spray chamber is also easily implemented via SINDAFLUINT. The goal is to create a transient one dimensional flow and heat transfer model beginning at the rocket, continuing through the condensing spray chamber, and finally ending with the ejector pumping system. However the model of the condensing spray chamber may be run independently of the rocket and ejector systems detail, with only appropriate mass flow boundary conditions placed at the entrance and exit of the condensing spray chamber model. The model of the condensing spray chamber takes into account droplet

  5. 2002 reference document; Document de reference 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This 2002 reference document of the group Areva, provides information on the society. Organized in seven chapters, it presents the persons responsible for the reference document and for auditing the financial statements, information pertaining to the transaction, general information on the company and share capital, information on company operation, changes and future prospects, assets, financial position, financial performance, information on company management and executive board and supervisory board, recent developments and future prospects. (A.L.B.)

  6. Comprehensive capacitance-voltage analysis including quantum effects for high-k interfaces on germanium and other alternative channel materials

    Science.gov (United States)

    Anwar, Sarkar R. M.

    High mobility alternative channel materials to silicon are critical to the continued scaling of metal oxide semiconductor (MOS) devices. However, before they can be incorporated into advanced devices, some major issues need to be solved. The high mobility materials suffer from lower allowable thermal budgets compared to Si (before desorption and defect formation becomes an issue) and the absence of a good quality native oxide has further increased the interest in the use of high-k dielectrics. However, the high interface state density and high electric fields at these semiconductor/high-k interfaces can significantly impact the capacitance-voltage (C-V) profile, and current C-V modeling software cannot account for these effects. This in turn affects the parameters extracted from the C-V data of the high mobility semiconductor/high-k interface, which are crucial to fully understand the interface properties and expedite process development. To address this issue, we developed a model which takes into account quantum corrections which can be applied to a number of these alternative channel materials including SixGe1-x, Ge, InGaAs, and GaAs. The C-V simulation using this QM correction model is orders of magnitude faster compared to a full band Schrodinger-Poisson solver. The simulated C-V is directly benchmarked to a self consistent Schrodinger-Poisson solution for each bulk semiconductor material, and from the benchmarking process the QM correction parameters are extracted. The full program, C-V Alternative Channel Extraction (CV ACE), incorporates a quantum mechanical correction model, along with the interface state density model, and can extract device parameters such as equivalent oxide thickness (EOT), doping density and flat band voltage (Vfb) as well as the interface state density profile using multiple measurements performed at different frequencies and temperatures, simultaneously. The program was used to analyze experimentally measured C-V profiles and the

  7. A Unified Format for Language Documents

    NARCIS (Netherlands)

    V. Zaytsev (Vadim); R. Lämmel (Ralf); M.G.J. van den Brand (Mark); B. Malloy; S. Staab

    2010-01-01

    textabstractWe have analyzed a substantial number of language documentation artifacts, including language standards, language specifications, language reference manuals, as well as internal documents of standardization bodies. We have reverse-engineered their intended internal structure,

  8. ENDF/B summary documentation

    International Nuclear Information System (INIS)

    Kinsey, R.

    1979-07-01

    This publication provides a localized source of descriptions for the evaluations contained in the ENDF/B Library. The summary documentation presented is intended to be a more detailed description than the (File 1) comments contained in the computer readable data files, but not so detailed as the formal reports describing each ENDF/B evaluation. The summary documentations were written by the CSEWB (Cross Section Evaluation Working Group) evaluators and compiled by NNDC (National Nuclear Data Center). This edition includes documentation for materials found on ENDF/B Version V tapes 501 to 516 (General Purpose File) excluding tape 504. ENDF/B-V also includes tapes containing partial evaluations for the Special Purpose Actinide (521, 522), Dosimetry (531), Activation (532), Gas Production (533), and Fission Product (541-546) files. The materials found on these tapes are documented elsewhere. Some of the evaluation descriptions in this report contain cross sections or energy level information

  9. ENDF/B summary documentation

    Energy Technology Data Exchange (ETDEWEB)

    Kinsey, R. (comp.)

    1979-07-01

    This publication provides a localized source of descriptions for the evaluations contained in the ENDF/B Library. The summary documentation presented is intended to be a more detailed description than the (File 1) comments contained in the computer readable data files, but not so detailed as the formal reports describing each ENDF/B evaluation. The summary documentations were written by the CSEWB (Cross Section Evaluation Working Group) evaluators and compiled by NNDC (National Nuclear Data Center). This edition includes documentation for materials found on ENDF/B Version V tapes 501 to 516 (General Purpose File) excluding tape 504. ENDF/B-V also includes tapes containing partial evaluations for the Special Purpose Actinide (521, 522), Dosimetry (531), Activation (532), Gas Production (533), and Fission Product (541-546) files. The materials found on these tapes are documented elsewhere. Some of the evaluation descriptions in this report contain cross sections or energy level information. (RWR)

  10. The Quality of Canadian and U.S. Government Health Documents Remains Unchallenged Until Better Research Can Be Undertaken. A review of: Lambert, Frank. “Assessing the Authoritativeness of Canadian and American Health Documents: A Comparative Analysis Using Informetric Methodologies.” Government Information Quarterly 22.2 (2005: 277‐96.

    Directory of Open Access Journals (Sweden)

    Michael Corkett

    2006-12-01

    Full Text Available Objective ‐ To assess by means of citation analysis whether the public trust afforded health documents published by the Canadian and U.S. governments is appropriate, and to ascertain whether differences in the respective health care systems influence how publications are produced.Design – Comparative study.Setting – The Canadian Depository Service Program (DSP and the U.S. Department of Health and Human Services (DHHS websites.Subjects – One hundred sixty‐six electronic documents sourced from the DSP website, and 284 electronic documents sourced from the DHHS website.Methods – Subjects were randomly selected from repositories offering the most comprehensive collections. Documents with evidence of references to other works used in preparation were separated from thos ewithout such characteristics. Data variables were collected from documents with evidence of references. Statistical analysis of the data was undertaken.Main results – Of the respective samples, 89(53% from the DSP and 109 (38.4% from the DHHS contained references. Personal authors were identified in 46 (51.7% and 63(58% of the respective subsets. Handbooks and guidebooks accounted for the largest portion of the DSP subset (29; 32.6% and government periodicals were the largest constituent of the DHHS subset (41; 37.6%. Scholarly journals were the most common reference type for both the DSP (44% and the DHHS (58.5% subsets. The number of references per document was widely dispersed for both subsets; the DSP mean was approximately 64 (SD=114.68 and the DHHS was 73.71 (SD=168.85. Kruskal‐Wallis subset analysis of median number of references by document type found differences generalizable to the entire DSP (pConclusion – Significant differences in reference use frequencies between DSP and DHHS documents challenges Foskett’s stance that documents of value contain references (Foskett. Use of peer‐reviewed scholarly journals for both DSP and DHHS publications was

  11. AREVA - 2012 Reference document

    International Nuclear Information System (INIS)

    2013-03-01

    After a presentation of the person responsible for this Reference Document, of statutory auditors, and of a summary of financial information, this report address the different risk factors: risk management and coverage, legal risk, industrial and environmental risk, operational risk, risk related to major projects, liquidity and market risk, and other risks (related to political and economic conditions, to Group's structure, and to human resources). The next parts propose information about the issuer, a business overview (markets for nuclear power and renewable energies, customers and suppliers, group's strategy, operations), a brief presentation of the organizational structure, a presentation of properties, plants and equipment (principal sites, environmental issues which may affect these items), analysis and comments on the group's financial position and performance, a presentation of capital resources, a presentation of research and development activities (programs, patents and licenses), a brief description of financial objectives and profit forecasts or estimates, a presentation of administration, management and supervision bodies, a description of the operation of corporate bodies, an overview of personnel, of principal shareholders, and of transactions with related parties, a more detailed presentation of financial information concerning assets, financial positions and financial performance. Addition information regarding share capital is given, as well as an indication of major contracts, third party information, available documents, and information on holdings

  12. AREVA 2010 Reference document

    International Nuclear Information System (INIS)

    2010-01-01

    After a presentation of the person responsible for this document, and of statutory auditors, this report proposes some selected financial information. Then, it addresses, presents and comments the different risk factors: risk management and coverage, legal risk, industrial and environmental risk, operational risk, risks related to major projects, liquidity and market risk, and other risk. Then, after a presentation of the issuer, it proposes a business overview (markets for nuclear and renewable energies, AREVA customers and suppliers, strategy, activities), a presentation of the organizational structure, a presentation of AREVA properties, plants and equipment (sites, environmental issues), an analysis and comment of the group's financial position and performance, a presentation of its capital resources, an overview of its research and development activities, programs, patents and licenses. It indicates profit forecast and estimates, presents the administrative, management and supervisory bodies, and compensation and benefits amounts, reports of the functioning of corporate bodies. It describes the human resource company policy, indicates the main shareholders and transactions with related parties. It proposes financial information concerning assets, financial positions and financial performance. This document contains its French and its English versions

  13. Multi-faceted methodology of the risk analysis and management referring to the IT system supporting the processing of documents at different levels of sensitivity

    OpenAIRE

    Kiedrowicz Maciej

    2017-01-01

    This article outlines the methodology of the IT system risk analysis and management, including various categories of risk factors significant from the point of view of the sensitive data processing and completeness of the procedure for determining the IT system risk level. The presented methodology is divided into the IT system risk analysis and the risk management method. The IT system risk level assessed by the risk analysis method described in this article constitutes an input value for th...

  14. AREVA 2009 reference document

    International Nuclear Information System (INIS)

    2009-01-01

    This Reference Document contains information on the AREVA group's objectives, prospects and development strategies. It contains information on the markets, market shares and competitive position of the AREVA group. This information provides an adequate picture of the size of these markets and of the AREVA group's competitive position. Content: 1 - Person responsible for the Reference Document and Attestation by the person responsible for the Reference Document; 2 - Statutory and Deputy Auditors; 3 - Selected financial information; 4 - Risks: Risk management and coverage, Legal risk, Industrial and environmental risk, Operating risk, Risk related to major projects, Liquidity and market risk, Other risk; 5 - Information about the issuer: History and development, Investments; 6 - Business overview: Markets for nuclear power and renewable energies, AREVA customers and suppliers, Overview and strategy of the group, Business divisions, Discontinued operations: AREVA Transmission and Distribution; 7 - Organizational structure; 8 - Property, plant and equipment: Principal sites of the AREVA group, Environmental issues that may affect the issuer's; 9 - Analysis of and comments on the group's financial position and performance: Overview, Financial position, Cash flow, Statement of financial position, Events subsequent to year-end closing for 2009; 10 - Capital Resources; 11 - Research and development programs, patents and licenses; 12 -trend information: Current situation, Financial objectives; 13 - Profit forecasts or estimates; 14 - Administrative, management and supervisory bodies and senior management; 15 - Compensation and benefits; 16 - Functioning of corporate bodies; 17 - Employees; 18 - Principal shareholders; 19 - Transactions with related parties: French state, CEA, EDF group; 20 - Financial information concerning assets, financial positions and financial performance; 21 - Additional information: Share capital, Certificate of incorporation and by-laws; 22 - Major

  15. Web document engineering

    International Nuclear Information System (INIS)

    White, B.

    1996-05-01

    This tutorial provides an overview of several document engineering techniques which are applicable to the authoring of World Wide Web documents. It illustrates how pre-WWW hypertext research is applicable to the development of WWW information resources

  16. Mined Geologic Disposal System Requirements Document

    International Nuclear Information System (INIS)

    1994-03-01

    This Mined Geologic Disposal System Requirements Document (MGDS-RD) describes the functions to be performed by, and the requirements for, a Mined Geologic Disposal System (MGDS) for the permanent disposal of spent nuclear fuel (SNF) (including SNF loaded in multi-purpose canisters (MPCs)) and commercial and defense high-level radioactive waste (HLW) in support of the Civilian Radioactive Waste Management System (CRWMS). The purpose of the MGDS-RD is to define the program-level requirements for the design of the Repository, the Exploratory Studies Facility (ESF), and Surface Based Testing Facilities (SBTF). These requirements include design, operation, and decommissioning requirements to the extent they impact on the physical development of the MGDS. The document also presents an overall description of the MGDS, its functions (derived using the functional analysis documented by the Physical System Requirements (PSR) documents as a starting point), its segments as described in Section 3.1.3, and the requirements allocated to the segments. In addition, the program-level interfaces of the MGDS are identified. As such, the MGDS-RD provides the technical baseline for the design of the MGDS

  17. Regulatory guidance document

    International Nuclear Information System (INIS)

    1994-05-01

    The Office of Civilian Radioactive Waste Management (OCRWM) Program Management System Manual requires preparation of the OCRWM Regulatory Guidance Document (RGD) that addresses licensing, environmental compliance, and safety and health compliance. The document provides: regulatory compliance policy; guidance to OCRWM organizational elements to ensure a consistent approach when complying with regulatory requirements; strategies to achieve policy objectives; organizational responsibilities for regulatory compliance; guidance with regard to Program compliance oversight; and guidance on the contents of a project-level Regulatory Compliance Plan. The scope of the RGD includes site suitability evaluation, licensing, environmental compliance, and safety and health compliance, in accordance with the direction provided by Section 4.6.3 of the PMS Manual. Site suitability evaluation and regulatory compliance during site characterization are significant activities, particularly with regard to the YW MSA. OCRWM's evaluation of whether the Yucca Mountain site is suitable for repository development must precede its submittal of a license application to the Nuclear Regulatory Commission (NRC). Accordingly, site suitability evaluation is discussed in Chapter 4, and the general statements of policy regarding site suitability evaluation are discussed in Section 2.1. Although much of the data and analyses may initially be similar, the licensing process is discussed separately in Chapter 5. Environmental compliance is discussed in Chapter 6. Safety and Health compliance is discussed in Chapter 7

  18. Historical Documents Modernization

    Directory of Open Access Journals (Sweden)

    Domingo Miguel

    2017-06-01

    Full Text Available Historical documents are mostly accessible to scholars specialized in the period in which the document originated. In order to increase their accessibility to a broader audience and help in the preservation of the cultural heritage, we propose a method to modernized these documents. This method is based in statistical machine translation, and aims at translating historical documents into a modern version of their original language. We tested this method in two different scenarios, obtaining very encouraging results.

  19. Scheme Program Documentation Tools

    DEFF Research Database (Denmark)

    Nørmark, Kurt

    2004-01-01

    This paper describes and discusses two different Scheme documentation tools. The first is SchemeDoc, which is intended for documentation of the interfaces of Scheme libraries (APIs). The second is the Scheme Elucidator, which is for internal documentation of Scheme programs. Although the tools...... as named functions in Scheme. Finally, the Scheme Elucidator is able to integrate SchemeDoc resources as part of an internal documentation resource....

  20. [Multimodal document management in radiotherapy].

    Science.gov (United States)

    Fahrner, H; Kirrmann, S; Röhner, F; Schmucker, M; Hall, M; Heinemann, F

    2013-12-01

    After incorporating treatment planning and the organisational model of treatment planning in the operating schedule system (BAS, "Betriebsablaufsystem"), complete document qualities were embedded in the digital environment. The aim of this project was to integrate all documents independent of their source (paper-bound or digital) and to make content from the BAS available in a structured manner. As many workflow steps as possible should be automated, e.g. assigning a document to a patient in the BAS. Additionally it must be guaranteed that at all times it could be traced who, when, how and from which source documents were imported into the departmental system. Furthermore work procedures should be changed that the documentation conducted either directly in the departmental system or from external systems can be incorporated digitally and paper document can be completely avoided (e.g. documents such as treatment certificate, treatment plans or documentation). It was a further aim, if possible, to automate the removal of paper documents from the departmental work flow, or even to make such paper documents superfluous. In this way patient letters for follow-up appointments should automatically generated from the BAS. Similarly patient record extracts in the form of PDF files should be enabled, e.g. for controlling purposes. The available document qualities were analysed in detail by a multidisciplinary working group (BAS-AG) and after this examination and assessment of the possibility of modelling in our departmental workflow (BAS) they were transcribed into a flow diagram. The gathered specifications were implemented in a test environment by the clinical and administrative IT group of the department of radiation oncology and subsequent to a detailed analysis introduced into clinical routine. The department has succeeded under the conditions of the aforementioned criteria to embed all relevant documents in the departmental workflow via continuous processes. Since the

  1. Multimodal document management in radiotherapy

    International Nuclear Information System (INIS)

    Fahrner, H.; Kirrmann, S.; Roehner, F.; Schmucker, M.; Hall, M.; Heinemann, F.

    2013-01-01

    Background and purpose: After incorporating treatment planning and the organisational model of treatment planning in the operating schedule system (BAS, 'Betriebsablaufsystem'), complete document qualities were embedded in the digital environment. The aim of this project was to integrate all documents independent of their source (paper-bound or digital) and to make content from the BAS available in a structured manner. As many workflow steps as possible should be automated, e.g. assigning a document to a patient in the BAS. Additionally it must be guaranteed that at all times it could be traced who, when, how and from which source documents were imported into the departmental system. Furthermore work procedures should be changed that the documentation conducted either directly in the departmental system or from external systems can be incorporated digitally and paper document can be completely avoided (e.g. documents such as treatment certificate, treatment plans or documentation). It was a further aim, if possible, to automate the removal of paper documents from the departmental work flow, or even to make such paper documents superfluous. In this way patient letters for follow-up appointments should automatically generated from the BAS. Similarly patient record extracts in the form of PDF files should be enabled, e.g. for controlling purposes. Method: The available document qualities were analysed in detail by a multidisciplinary working group (BAS-AG) and after this examination and assessment of the possibility of modelling in our departmental workflow (BAS) they were transcribed into a flow diagram. The gathered specifications were implemented in a test environment by the clinical and administrative IT group of the department of radiation oncology and subsequent to a detailed analysis introduced into clinical routine. Results: The department has succeeded under the conditions of the aforementioned criteria to embed all relevant documents in the departmental

  2. Audit of Orthopaedic Surgical Documentation

    Directory of Open Access Journals (Sweden)

    Fionn Coughlan

    2015-01-01

    Full Text Available Introduction. The Royal College of Surgeons in England published guidelines in 2008 outlining the information that should be documented at each surgery. St. James’s Hospital uses a standard operation sheet for all surgical procedures and these were examined to assess documentation standards. Objectives. To retrospectively audit the hand written orthopaedic operative notes according to established guidelines. Methods. A total of 63 operation notes over seven months were audited in terms of date and time of surgery, surgeon, procedure, elective or emergency indication, operative diagnosis, incision details, signature, closure details, tourniquet time, postop instructions, complications, prosthesis, and serial numbers. Results. A consultant performed 71.4% of procedures; however, 85.7% of the operative notes were written by the registrar. The date and time of surgery, name of surgeon, procedure name, and signature were documented in all cases. The operative diagnosis and postoperative instructions were frequently not documented in the designated location. Incision details were included in 81.7% and prosthesis details in only 30% while the tourniquet time was not documented in any. Conclusion. Completion and documentation of operative procedures were excellent in some areas; improvement is needed in documenting tourniquet time, prosthesis and incision details, and the location of operative diagnosis and postoperative instructions.

  3. Document image mosaicing: A novel approach

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    image analysis and processing require mosaicing of the split images to obtain a complete final image of the document. Hence, document image mosaicing is the process of merging split images that are obtained by scanning different parts of single large document image with some sort of overlapping region (OR) to produce ...

  4. Areva - 2016 Reference document

    International Nuclear Information System (INIS)

    2017-01-01

    Areva supplies high added-value products and services to support the operation of the global nuclear fleet. The company is present throughout the entire nuclear cycle, from uranium mining to used fuel recycling, including nuclear reactor design and operating services. Areva is recognized by utilities around the world for its expertise, its skills in cutting-edge technologies and its dedication to the highest level of safety. Areva's 36,000 employees are helping build tomorrow's energy model: supplying ever safer, cleaner and more economical energy to the greatest number of people. This Reference Document contains information on Areva's objectives, prospects and development strategies. It contains estimates of the markets, market shares and competitive position of Areva

  5. Starlink Document Styles

    Science.gov (United States)

    Lawden, M. D.

    This document describes the various styles which are recommended for Starlink documents. It also explains how to use the templates which are provided by Starlink to help authors create documents in a standard style. This paper is concerned mainly with conveying the ``look and feel" of the various styles of Starlink document rather than describing the technical details of how to produce them. Other Starlink papers give recommendations for the detailed aspects of document production, design, layout, and typography. The only style that is likely to be used by most Starlink authors is the Standard style.

  6. 10 CFR 71.113 - Document control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Document control. 71.113 Section 71.113 Energy NUCLEAR....113 Document control. The licensee, certificate holder, and applicant for a CoC shall establish measures to control the issuance of documents such as instructions, procedures, and drawings, including...

  7. Non-invasive investigative techniques for the diachronic study of territorial compartments: a case study for the documentation and analysis of architectural complexes.

    Science.gov (United States)

    Di Lieto, Marco; Marchetta, Isabella; Ciriello, Rosanna; De Martino, Gregory; Della Mora, Dario

    2014-05-01

    The trend in the study of areas of land in their integrity and as dynamic, anthropic units in diachronic history has initiated long survey campaigns over several decades that have covered large areas mapping the evidence and attempting a reconstruction of the evolution of ancient settlements. The need for further study to disentangle the knots of modes and types of settlement boosted further investigations of targeted excavations, based on the quality and density of the findings from the field. Currently archaeological research can rely on non-invasive integrated methods to better define the areas to be investigated systematically obtaining new typologies of information and better management of time and research costs. In this paper we present a specific case study in which a variety of integrated survey methods have contributed to the documentation and analysis of monumental complexes linked to specific local contexts. The area under investigation lies in Italy, in the province of Potenza and, specifically in the town of Forenza. The survey activities, involving the entire municipality, have been running on and off for about 2 years and have already resulted in the collection of a lot of interesting data that will be useful to essential fieldwork. In particular, we carried out different types of investigation in three different sample sites: 1. monumental complex of Santa Maria de 'Armenis: to complement previous excavations which involved only a portion of the estimated area of interest, we carried out magnetometric and geo-electrical surveys aimed at a more precise definition of the true extent and interpretation of the monument in antiquity; 2. site of Monte Caruso: we carried out remote sensing using a remote-controlled UAV hexakopter drone with stereoscopic photogrammetric survey techniques aimed at the detailed documentation of the monumental evidence of a structure visible in elevation but in a context difficult to approach with traditional surveying

  8. Areva reference document 2007

    International Nuclear Information System (INIS)

    2008-01-01

    This reference document contains information on the AREVA group's objectives, prospects and development strategies, particularly in Chapters 4 and 7. It contains also information on the markets, market shares and competitive position of the AREVA group. Content: 1 - Person responsible for the reference document and persons responsible for auditing the financial statements; 2 - Information pertaining to the transaction (not applicable); 3 - General information on the company and its share capital: Information on Areva, Information on share capital and voting rights, Investment certificate trading, Dividends, Organization chart of AREVA group companies, Equity interests, Shareholders' agreements; 4 - Information on company operations, new developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, The energy businesses of the AREVA group, Front End division, Reactors and Services division, Back End division, Transmission and Distribution division, Major contracts 140 Principal sites of the AREVA group, AREVA's customers and suppliers, Sustainable Development and Continuous Improvement, Capital spending programs, Research and Development programs, Intellectual Property and Trademarks, Risk and insurance; 5 - Assets financial position financial performance: Analysis of and comments on the group's financial position and performance, Human Resources report, Environmental report, Consolidated financial statements 2007, Notes to the consolidated financial statements, Annual financial statements 2007, Notes to the corporate financial statements; 6 - Corporate governance: Composition and functioning of corporate bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual Ordinary General Meeting of Shareholders of April 17, 2008; 7 - Recent developments and future prospects: Events subsequent to year-end closing for 2007, Outlook; Glossary; table of concordance

  9. Areva, reference document 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This reference document contains information on the AREVA group's objectives, prospects and development strategies, particularly in Chapters 4 and 7. It contains information on the markets, market shares and competitive position of the AREVA group. Content: - 1 Person responsible for the reference document and persons responsible for auditing the financial statements; - 2 Information pertaining to the transaction (Not applicable); - 3 General information on the company and its share capital: Information on AREVA, on share capital and voting rights, Investment certificate trading, Dividends, Organization chart of AREVA group companies, Equity interests, Shareholders' agreements; - 4 Information on company operations, new developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, The energy businesses of the AREVA group, Front End division, Reactors and Services division, Back End division, Transmission and Distribution division, Major contracts, The principal sites of the AREVA group, AREVA's customers and suppliers, Sustainable Development and Continuous Improvement, Capital spending programs, Research and development programs, intellectual property and trademarks, Risk and insurance; - 5 Assets - Financial position - Financial performance: Analysis of and comments on the group's financial position and performance, 2006 Human Resources Report, Environmental Report, Consolidated financial statements, Notes to the consolidated financial statements, AREVA SA financial statements, Notes to the corporate financial statements; 6 - Corporate Governance: Composition and functioning of corporate bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual Combined General Meeting of Shareholders of May 3, 2007; 7 - Recent developments and future prospects: Events subsequent to year-end closing for 2006, Outlook; 8 - Glossary; 9 - Table of concordance

  10. Prospective cost-benefit analysis of a two-dimensional barcode for vaccine production, clinical documentation, and public health reporting and tracking.

    Science.gov (United States)

    O'Connor, Alan C; Kennedy, Erin D; Loomis, Ross J; Haque, Saira N; Layton, Christine M; Williams, Warren W; Amoozegar, Jacqueline B; Braun, Fern M; Honeycutt, Amanda A; Weinbaum, Cindy

    2013-06-28

    In the United States recording accurate vaccine lot numbers in immunization records is required by the National Childhood Vaccine Injury Act and is necessary for public health surveillance and implementation of vaccine product recalls. However, this information is often missing or inaccurate in records. The Food and Drug Administration (FDA) requires a linear barcode of the National Drug Code (NDC) on vaccine product labels as a medication verification measure, but lot number and expiration date must still be recorded by hand. Beginning in 2011, FDA permitted manufacturers to replace linear barcodes with two-dimensional (2D) barcodes on unit-of-use product labels. A 2D barcode can contain the NDC, expiration date, and lot number in a symbol small enough to fit on a unit-of-use label. All three data elements could be scanned into a patient record. To assess 2D barcodes' potential impacts, a mixed-methods approach of time-motion data analysis, interview and survey data collection, and cost-benefit analysis was employed. Analysis of a time-motion study conducted at 33 practices suggests scanning 2D-barcoded vaccines could reduce immunization documentation time by 36-39 s per dose. Data from an internet survey of primary care providers and local health officials indicate that 60% of pediatric practices, 54% of family medicine practices, and 39% of health departments would use the 2D barcode, with more indicating they would do so if they used electronic health records. Inclusive of manufacturer and immunization provider costs and benefits, we forecast lower-bound net benefits to be $310-334 million between 2011 and 2023 with a benefit-to-cost ratio of 3.1:1-3.2:1. Although we were unable to monetize benefits for expected improved immunization coverage, surveillance, or reduced medication errors, based on our findings, we expect that using 2D barcodes will lower vaccine documentation costs, facilitate data capture, and enhance immunization data quality. Copyright © 2013

  11. Dissimilar-weld failure analysis and development: Volume 7, Prediction of Damage in Service (PODIS): Code-background document: Final report

    Energy Technology Data Exchange (ETDEWEB)

    1988-05-01

    This document provides the technical background for the dissimilar weld life prediction computer program PODIS (Prediction of Damage in Service). PODIS is based on a set of empirical equations relating damage to loading history for both stainless-steel and nickel-base filler metal welds. The empirical equations were derived by regression analyses using well-characterized data from in-service investigations and laboratory tests. The equations were then validated using a large number of data points, mostly from service. The load damage equations can be used to estimate the damage in welds (in-service)when the various loads on the weld have been deduced from either the past of future operating hidtory of the plant. The evaluation of the damage components from a PODIS analysis can also be used for planning corrective action (plant modification or change in operating conditions) to increase the redisual life of a weld. The analysis technique has been programmed for IBM-compatible personal computers. 19 refs., 2 figs., 4 tabs.

  12. Analysis of image acquisition, post-processing and documentation in adolescents with spine injuries. Comparison before and after referral to a university hospital; Bildgebung bei wirbelsaeulenverletzten Kindern und jungen Erwachsenen. Eine Analyse von Umfeld, Standards und Wiederholungsuntersuchungen bei Patientenverlegungen

    Energy Technology Data Exchange (ETDEWEB)

    Lemburg, S.P.; Roggenland, D.; Nicolas, V.; Heyer, C.M. [Berufsgenossenschaftliches Universitaetsklinikum Bergmannshell, Bochum (Germany). Inst. fuer Diagnostische Radiologie, Interventionelle Radiologie und Nuklearmedizin

    2012-09-15

    Purpose: Systematic evaluation of imaging situation and standards in acute spinal injuries of adolescents. Materials and Methods: Retrospective analysis of imaging studies of transferred adolescents with spinal injuries and survey of transferring hospitals (TH) with respect to the availability of modalities and radiological expertise and post-processing and documentation of CT studies were performed. Repetitions of imaging studies and cumulative effective dose (CED) were noted. Results: 33 of 43 patients (77 %) treated in our hospital (MA 17.2 years, 52 % male) and 25 of 32 TH (78 %) were evaluated. 24-hr availability of conventional radiography and CT was present in 96 % and 92 % of TH, whereas MRI was available in only 36 %. In 64 % of TH, imaging expertise was guaranteed by an on-staff radiologist. During off-hours radiological service was provided on an on-call basis in 56 % of TH. Neuroradiologic and pediatric radiology expertise was not available in 44 % and 60 % of TH, respectively. CT imaging including post-processing and documentation matched our standards in 36 % and 32 % of cases. The repetition rate of CT studies was 39 % (CED 116.08 mSv). Conclusion: With frequent CT repetitions, two-thirds of re-examined patients revealed a different clinical estimation of trauma severity and insufficient CT quality as possible causes for re-examination. A standardization of initial clinical evaluation and CT imaging could possibly reduce the need for repeat examinations. (orig.)

  13. Patterns for Effectively Documenting Frameworks

    Science.gov (United States)

    Aguiar, Ademar; David, Gabriel

    Good design and implementation are necessary but not sufficient pre-requisites for successfully reusing object-oriented frameworks. Although not always recognized, good documentation is crucial for effective framework reuse, and often hard, costly, and tiresome, coming with many issues, especially when we are not aware of the key problems and respective ways of addressing them. Based on existing literature, case studies and lessons learned, the authors have been mining proven solutions to recurrent problems of documenting object-oriented frameworks, and writing them in pattern form, as patterns are a very effective way of communicating expertise and best practices. This paper presents a small set of patterns addressing problems related to the framework documentation itself, here seen as an autonomous and tangible product independent of the process used to create it. The patterns aim at helping non-experts on cost-effectively documenting object-oriented frameworks. In concrete, these patterns provide guidance on choosing the kinds of documents to produce, how to relate them, and which contents to include. Although the focus is more on the documents themselves, rather than on the process and tools to produce them, some guidelines are also presented in the paper to help on applying the patterns to a specific framework.

  14. Quality control of the documentation process in electronic economic activities

    Directory of Open Access Journals (Sweden)

    Krutova A.S.

    2017-06-01

    Full Text Available It is proved that the main tool that will provide adequate information resources e economic activities of social and economic relations are documenting quality control processes as the basis of global information space. Directions problems as formation evaluation information resources in the process of documentation, namely development tools assess the efficiency of the system components – qualitative assessment; development of mathematical modeling tools – quantitative evaluation. A qualitative assessment of electronic documentation of economic activity through exercise performance, efficiency of communication; document management efficiency; effectiveness of flow control operations; relationship management effectiveness. The concept of quality control process documents electronically economic activity to components which include: the level of workflow; forms adequacy of information; consumer quality documents; quality attributes; type of income data; condition monitoring systems; organizational level process documentation; attributes of quality, performance quality consumer; type of management system; type of income data; condition monitoring systems. Grounded components of the control system electronic document subjects of economic activity. Detected components IT-audit management system economic activity: compliance audit; audit of internal control; detailed multilevel analysis; corporate risk assessment methodology. The stages and methods of processing electronic transactions economic activity during condition monitoring of electronic economic activity.

  15. Improving the quality of nursing documentation: An action research project.

    Science.gov (United States)

    Okaisu, Elisha M; Kalikwani, Florence; Wanyana, Grace; Coetzee, Minette

    2014-12-03

    Documentation is an important function of professional nursing practise. In spite of numerous improvement efforts globally, inadequate documentation continues to be reported as nurse authors investigate barriers and challenges. The project aimed to improve nurses' documentation of their patient assessments at the CURE Children's Hospital of Uganda in order to enhance the quality of nursing practise. An action research methodology, using repeated cycles of planning, intervention, reflection and modification, was used to establish best practise approaches in this context for improving nurses' efficacy in documenting assessments in the patient record. The researchers gathered data from chart audits, literature reviews and key informant interviews. Through analysis and critical reflection, these data informed three cycles of systems and practise modifications to improve the quality of documentation. The initial cycle revealed that staff training alone was insufficient to achieve the project goal. To achieve improved documentation, broader changes were necessary, including building a critical mass of competent staff, redesigned orientation and continuing education, documentation form redesign, changes in nurse skill mix, and continuous leadership support. Improving nursing documentation involved complex challenges in this setting and demanded multiple approaches. Evidence-based practise was the foundation of changes in systems required to produce visible improvement in practise. The involved role of leadership in these efforts was very important.

  16. Researching in English: Document Study

    Science.gov (United States)

    Sawyer, Wayne

    2015-01-01

    In this article I argue for the defining importance of document study for researchers in curriculum. Two examples of previous analyses are provided, one demonstrating an approach to language analysis of the "Australian Curriculum: English" from the Literature strand, the other a study of the relationship of curricula to each other in…

  17. CFO Payment Document Management

    Data.gov (United States)

    US Agency for International Development — Paperless management will enable the CFO to create, store, and access various financial documents electronically. This capability will reduce time looking for...

  18. Health physics documentation

    International Nuclear Information System (INIS)

    Stablein, G.

    1980-01-01

    When dealing with radioactive material the health physicist receives innumerable papers and documents within the fields of researching, prosecuting, organizing and justifying radiation protection. Some of these papers are requested by the health physicist and some are required by law. The scope, quantity and deposit periods of the health physics documentation at the Karlsruhe Nuclear Research Center are presented and rationalizing methods discussed. The aim of this documentation should be the application of physics to accident prevention, i.e. documentation should protect those concerned and not the health physicist. (H.K.)

  19. CAED Document Repository

    Data.gov (United States)

    U.S. Environmental Protection Agency — Compliance Assurance and Enforcement Division Document Repository (CAEDDOCRESP) provides internal and external access of Inspection Records, Enforcement Actions, and...

  20. CARIAA Call - Call Document

    International Development Research Centre (IDRC) Digital Library (Canada)

    CARIAA

    2013-02-19

    Feb 19, 2013 ... Structure and Outputs of the CARIAA Program . ..... FIGURE 2: SCHEMATIC OF CONSORTIUM-LEVEL STRUCTURE (EXAMPLE WITH 3 MEMBERS) .... in open access journals (including publishing fees). -. Pilot interventions for testing adaptation options. -. Data collection and analysis. -. Data acquisition.