One of My Favorite Assignments: Automated Teller Machine Simulation.

Science.gov (United States)

Oberman, Paul S.

2001-01-01

Describes an assignment for an introductory computer science class that requires the student to write a software program that simulates an automated teller machine. Highlights include an algorithm for the assignment; sample file contents; language features used; assignment variations; and discussion points. (LRW)

Data Processing: Fifteen Suggestions for Computer Training in Your Business Education Classes.

Science.gov (United States)

Barr, Lowell L.

1980-01-01

Presents 15 suggestions for training business education students in the use of computers. Suggestions involve computer language, method of presentation, laboratory time, programing assignments, instructions and handouts, problem solving, deadlines, reviews, programming concepts, programming logic, documentation, and defensive programming. (CT)

SCRAED - Simple and Complex Random Assignment in Experimental Designs

OpenAIRE

Alferes, Valentim R.

2009-01-01

SCRAED is a package of 37 self-contained SPSS syntax files that performs simple and complex random assignment in experimental designs. For between-subjects designs, SCRAED includes simple random assignment (no restrictions, forced equal sizes, forced unequal sizes, and unequal probabilities), block random assignment (simple and generalized blocks), and stratified random assignment (no restrictions, forced equal sizes, forced unequal sizes, and unequal probabilities). For within-subject...

Mars - robust automatic backbone assignment of proteins

International Nuclear Information System (INIS)

Jung, Young-Sang; Zweckstetter, Markus

2004-01-01

MARS a program for robust automatic backbone assignment of 13 C/ 15 N labeled proteins is presented. MARS does not require tight thresholds for establishing sequential connectivity or detailed adjustment of these thresholds and it can work with a wide variety of NMR experiments. Using only 13 C α / 13 C β connectivity information, MARS allows automatic, error-free assignment of 96% of the 370-residue maltose-binding protein. MARS can successfully be used when data are missing for a substantial portion of residues or for proteins with very high chemical shift degeneracy such as partially or fully unfolded proteins. Other sources of information, such as residue specific information or known assignments from a homologues protein, can be included into the assignment process. MARS exports its result in SPARKY format. This allows visual validation and integration of automated and manual assignment

The ICAP (Interactive Course Assignment Pages Publishing System

Directory of Open Access Journals (Sweden)

Kim Griggs

2008-03-01

Full Text Available The ICAP publishing system is an open source custom content management system that enables librarians to easily and quickly create and manage library help pages for course assignments (ICAPs, without requiring knowledge of HTML or other web technologies. The system's unique features include an emphasis on collaboration and content reuse and an easy-to-use interface that includes in-line help, simple forms and drag and drop functionality. The system generates dynamic, attractive course assignment pages that blend Web 2.0 features with traditional library resources, and makes the pages easier to find by providing a central web page for the course assignment pages. As of December 2007, the code is available as free, open-source software under the GNU General Public License.

Handout on Health: Osteoporosis

Science.gov (United States)

... against gravity. Weight-bearing exercises include jogging, aerobics, hiking, walking, stair climbing, gardening, weight training, tennis, and dancing. High-impact exercises may provide the most benefit. Bicycling and swimming are not weight-bearing exercises, ...

Handout on shielding calculation

International Nuclear Information System (INIS)

Heilbron Filho, P.F.L.

1991-01-01

In order to avoid the difficulties of the radioprotection supervisors in the tasks related to shielding calculations, is presented in this paper the basic concepts of shielding theory. It also includes exercises and examples. (author)

Assigning breed origin to alleles in crossbred animals.

Science.gov (United States)

Vandenplas, Jérémie; Calus, Mario P L; Sevillano, Claudia A; Windig, Jack J; Bastiaansen, John W M

2016-08-22

For some species, animal production systems are based on the use of crossbreeding to take advantage of the increased performance of crossbred compared to purebred animals. Effects of single nucleotide polymorphisms (SNPs) may differ between purebred and crossbred animals for several reasons: (1) differences in linkage disequilibrium between SNP alleles and a quantitative trait locus; (2) differences in genetic backgrounds (e.g., dominance and epistatic interactions); and (3) differences in environmental conditions, which result in genotype-by-environment interactions. Thus, SNP effects may be breed-specific, which has led to the development of genomic evaluations for crossbred performance that take such effects into account. However, to estimate breed-specific effects, it is necessary to know breed origin of alleles in crossbred animals. Therefore, our aim was to develop an approach for assigning breed origin to alleles of crossbred animals (termed BOA) without information on pedigree and to study its accuracy by considering various factors, including distance between breeds. The BOA approach consists of: (1) phasing genotypes of purebred and crossbred animals; (2) assigning breed origin to phased haplotypes; and (3) assigning breed origin to alleles of crossbred animals based on a library of assigned haplotypes, the breed composition of crossbred animals, and their SNP genotypes. The accuracy of allele assignments was determined for simulated datasets that include crosses between closely-related, distantly-related and unrelated breeds. Across these scenarios, the percentage of alleles of a crossbred animal that were correctly assigned to their breed origin was greater than 90 %, and increased with increasing distance between breeds, while the percentage of incorrectly assigned alleles was always less than 2 %. For the remaining alleles, i.e. 0 to 10 % of all alleles of a crossbred animal, breed origin could not be assigned. The BOA approach accurately assigns

Assigning Significance in Label-Free Quantitative Proteomics to Include Single-Peptide-Hit Proteins with Low Replicates

OpenAIRE

Li, Qingbo

2010-01-01

When sample replicates are limited in a label-free proteomics experiment, selecting differentially regulated proteins with an assignment of statistical significance remains difficult for proteins with a single-peptide hit or a small fold-change. This paper aims to address this issue. An important component of the approach employed here is to utilize the rule of Minimum number of Permuted Significant Pairings (MPSP) to reduce false positives. The MPSP rule generates permuted sample pairings fr...

Grouping puts figure-ground assignment in context by constraining propagation of edge assignment.

Science.gov (United States)

Brooks, Joseph L; Brook, Joseph L; Driver, Jon

2010-05-01

Figure-ground organization involves the assignment of edges to a figural shape on one or the other side of each dividing edge. Established visual cues for edge assignment primarily concern relatively local rather than contextual factors. In the present article, we show that an assignment for a locally unbiased edge can be affected by an assignment of a remote contextual edge that has its own locally biased assignment. We find that such propagation of edge assignment from the biased remote context occurs only when the biased and unbiased edges are grouped. This new principle, whereby grouping constrains the propagation of figural edge assignment, emerges from both subjective reports and an objective short-term edge-matching task. It generalizes from moving displays involving grouping by common fate and collinearity, to static displays with grouping by similarity of edge-contrast polarity, or apparent occlusion. Our results identify a new contextual influence on edge assignment. They also identify a new mechanistic relation between grouping and figure-ground processes, whereby grouping between remote elements can constrain the propagation of edge assignment between those elements. Supplemental materials for this article may be downloaded from http://app.psychonomic-journals.org/content/supplemental.

Human Clay Models versus Cat Dissection: How the Similarity between the Classroom and the Exam Affects Student Performance

Science.gov (United States)

Waters, John R.; Van Meter, Peggy; Perrotti, William; Drogo, Salvatore; Cyr, Richard J.

2011-01-01

This study examined the effect of different anatomic representations on student learning in a human anatomy class studying the muscular system. Specifically, we examined the efficacy of using dissected cats (with and without handouts) compared with clay sculpting of human structures. Ten undergraduate laboratory sections were assigned to three…

FLEET ASSIGNMENT MODELLING

Directory of Open Access Journals (Sweden)

2016-01-01

Full Text Available The article is devoted to the airline scheduling process and methods of its modeling. This article describes the main stages of airline scheduling process (scheduling, fleet assignment, revenue management, operations, their features and interactions. The main part of scheduling process is fleet assignment. The optimal solution of the fleet assignment problem enables airlines to increase their incomes up to 3 % due to quality improving of connections and execution of the planned number of flights operated by less number of aircraft than usual or planned earlier. Fleet assignment of scheduling process is examined and Conventional Leg-Based Fleet Assignment Model is analyzed. Finally strong and weak aspects of the model (SWOT are released and applied. The article gives a critical analysis of FAM model, with the purpose of identi- fying possible options and constraints of its use (for example, in cases of short-term and long-term planning, changing the schedule or replacing the aircraft, as well as possible ways to improve the model.

Incorporating breeding abundance into spatial assignments on continuous surfaces.

Science.gov (United States)

Rushing, Clark S; Marra, Peter P; Studds, Colin E

2017-06-01

Determining the geographic connections between breeding and nonbreeding populations, termed migratory connectivity, is critical to advancing our understanding of the ecology and conservation of migratory species. Assignment models based on stable isotopes historically have been an important tool for studying migratory connectivity of small-bodied species, but the low resolution of these assignments has generated interest into combining isotopes with other sources in information. Abundance is one of the most appealing data sources to include in isotope-based assignments, but there are currently no statistical methods or guidelines for optimizing the contribution of stable isotopes and abundance for inferring migratory connectivity. Using known-origin stable-hydrogen isotope samples of six Neotropical migratory bird species, we rigorously assessed the performance of assignment models that differentially weight the contribution of the isotope and abundance data. For two species with adequate sample sizes, we used Pareto optimality to determine the set of models that simultaneously minimized both assignment error rate and assignment area. We then assessed the ability of the top models from these two species to improve assignments of the remaining four species compared to assignments based on isotopes alone. We show that the increased precision of models that include abundance is often offset by a large increase in assignment error. However, models that optimally weigh the abundance data relative to the isotope data can result in higher precision and, in some cases, lower error than models based on isotopes alone. The top models, however, depended on the distribution of relative breeding abundance, with patchier distributions requiring stronger downweighting of abundance, and we present general guidelines for future studies. These results confirm that breeding abundance can be an important source of information for studies investigating broad-scale movements of

UOP LDR 300 All Assignments New

OpenAIRE

ADMIN

2018-01-01

UOP LDR 300 All Assignments New Check this A+ tutorial guideline at http://www.ldr300assignment.com/ldr-300-uop/ldr-300-all-assignments-latest For more classes visit http://www.ldr300assignment.com LDR 300 Week 1 Assignment Leadership Assessment (2 Papers) LDR 300 Week 2 Assignment Leadership Theories Matrix (2 Set) LDR 300 Week 2 Assignment Formulating Leadership Part I (2 Papers) LDR 300 Week 3 Assignment Interaction and Influence Amo...

Fair Package Assignment

Science.gov (United States)

Lahaie, Sébastien; Parkes, David C.

We consider the problem of fair allocation in the package assignment model, where a set of indivisible items, held by single seller, must be efficiently allocated to agents with quasi-linear utilities. A fair assignment is one that is efficient and envy-free. We consider a model where bidders have superadditive valuations, meaning that items are pure complements. Our central result is that core outcomes are fair and even coalition-fair over this domain, while fair distributions may not even exist for general valuations. Of relevance to auction design, we also establish that the core is equivalent to the set of anonymous-price competitive equilibria, and that superadditive valuations are a maximal domain that guarantees the existence of anonymous-price competitive equilibrium. Our results are analogs of core equivalence results for linear prices in the standard assignment model, and for nonlinear, non-anonymous prices in the package assignment model with general valuations.

Flexible taxonomic assignment of ambiguous sequencing reads

Directory of Open Access Journals (Sweden)

Jansson Jesper

2011-01-01

Full Text Available Abstract Background To characterize the diversity of bacterial populations in metagenomic studies, sequencing reads need to be accurately assigned to taxonomic units in a given reference taxonomy. Reads that cannot be reliably assigned to a unique leaf in the taxonomy (ambiguous reads are typically assigned to the lowest common ancestor of the set of species that match it. This introduces a potentially severe error in the estimation of bacteria present in the sample due to false positives, since all species in the subtree rooted at the ancestor are implicitly assigned to the read even though many of them may not match it. Results We present a method that maps each read to a node in the taxonomy that minimizes a penalty score while balancing the relevance of precision and recall in the assignment through a parameter q. This mapping can be obtained in time linear in the number of matching sequences, because LCA queries to the reference taxonomy take constant time. When applied to six different metagenomic datasets, our algorithm produces different taxonomic distributions depending on whether coverage or precision is maximized. Including information on the quality of the reads reduces the number of unassigned reads but increases the number of ambiguous reads, stressing the relevance of our method. Finally, two measures of performance are described and results with a set of artificially generated datasets are discussed. Conclusions The assignment strategy of sequencing reads introduced in this paper is a versatile and a quick method to study bacterial communities. The bacterial composition of the analyzed samples can vary significantly depending on how ambiguous reads are assigned depending on the value of the q parameter. Validation of our results in an artificial dataset confirm that a combination of values of q produces the most accurate results.

30 CFR 285.408 - May I assign my lease or grant interest?

Science.gov (United States)

2010-07-01

... RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Lease and Grant... application to MMS. The assignment application must include: (1) The MMS-assigned lease or grant number; (2) A... required financial assurance. (c) If you submit an application to assign a lease or grant, you will...

Plagiarism-Proofing Assignments

Science.gov (United States)

Johnson, Doug

2004-01-01

Mr. Johnson has discovered that the higher the level of student engagement and creativity, the lower the probability of plagiarism. For teachers who would like to see such desirable results, he describes the characteristics of assignments that are most likely to produce them. Two scenarios of types of assignments that avoid plagiarism are…

An Approach to Teaching Organizational Skills to Adults

Science.gov (United States)

Issa, Sandra Tompson

2009-01-01

In English language teaching, it is not unusual to come across a student who seems to lack certain basic organizational skills. However, many of the language teaching techniques and materials require students to rely heavily on these skills. The use of textbooks and handouts, the assigning of tasks and homework, and the planning of a syllabus or…

31 CFR 306.87 - Partnerships (including nominee partnerships).

Science.gov (United States)

2010-07-01

... (including nominee partnerships). An assignment of a security registered in the name of or assigned to a... appropriate for winding up partnership affairs. In those cases where assignments by or in behalf of all... dissolution. Upon voluntary dissolution, for any jurisdiction where a general partner may not act in winding...

Dynamic Sequence Assignment.

Science.gov (United States)

1983-12-01

D-136 548 DYNAMIIC SEQUENCE ASSIGNMENT(U) ADVANCED INFORMATION AND 1/2 DECISION SYSTEMS MOUNTAIN YIELW CA C A 0 REILLY ET AL. UNCLSSIIED DEC 83 AI/DS...I ADVANCED INFORMATION & DECISION SYSTEMS Mountain View. CA 94040 84 u ,53 V,..’. Unclassified _____ SCURITY CLASSIFICATION OF THIS PAGE REPORT...reviews some important heuristic algorithms developed for fas- ter solution of the sequence assignment problem. 3.1. DINAMIC MOGRAMUNIG FORMULATION FOR

Automated solid-state NMR resonance assignment of protein microcrystals and amyloids

Energy Technology Data Exchange (ETDEWEB)

Schmidt, Elena [Goethe University Frankfurt am Main, Center for Biomolecular Magnetic Resonance, Institute of Biophysical Chemistry (Germany); Gath, Julia [ETH Zurich, Physical Chemistry (Switzerland); Habenstein, Birgit [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France); Ravotti, Francesco; Szekely, Kathrin; Huber, Matthias [ETH Zurich, Physical Chemistry (Switzerland); Buchner, Lena [Goethe University Frankfurt am Main, Center for Biomolecular Magnetic Resonance, Institute of Biophysical Chemistry (Germany); Boeckmann, Anja, E-mail: a.bockmann@ibcp.fr [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France); Meier, Beat H., E-mail: beme@ethz.ch [ETH Zurich, Physical Chemistry (Switzerland); Guentert, Peter, E-mail: guentert@em.uni-frankfurt.de [Goethe University Frankfurt am Main, Center for Biomolecular Magnetic Resonance, Institute of Biophysical Chemistry (Germany)

2013-07-15

Solid-state NMR is an emerging structure determination technique for crystalline and non-crystalline protein assemblies, e.g., amyloids. Resonance assignment constitutes the first and often very time-consuming step to a structure. We present ssFLYA, a generally applicable algorithm for automatic assignment of protein solid-state NMR spectra. Application to microcrystals of ubiquitin and the Ure2 prion C-terminal domain, as well as amyloids of HET-s(218-289) and {alpha}-synuclein yielded 88-97 % correctness for the backbone and side-chain assignments that are classified as self-consistent by the algorithm, and 77-90 % correctness if also assignments classified as tentative by the algorithm are included.

The Evolution of a Writing Program.

Science.gov (United States)

White, Bonnie J; Lamson, Karen S

2017-07-01

Scholarly writing is required in nursing, and some students are unable to communicate effectively through writing. Faculty members may struggle with the grading of written assignments. A writing team, consisting of a nursing faculty member, the school of nursing library liaison, and members from academic support services, implemented strategies including workshops, handouts, and use of exemplars to improve student writing and to provide support to faculty. Few students sought help from the writing team. An online writing center within the existing learning management system was developed to address nursing students' and faculty's scholarly writing needs. The writing center includes guides, tutorials, and exemplars. Anecdotal evidence indicates the use of the writing center during afternoons and evenings and prior to due dates of written assignments. Online writing resources were used more frequently than face-to-face support. Further research is needed to evaluate the effectiveness of the program. [J Nurs Educ. 2017;56(7):443-445.]. Copyright 2017, SLACK Incorporated.

Improvement in Student Data Analysis Skills after Out-of-Class Assignments

Directory of Open Access Journals (Sweden)

Kristen Lee Williams Walton

2016-12-01

Full Text Available The ability to understand and interpret data is a critical aspect of scientific thinking.  However, although data analysis is often a focus in biology majors classes, many textbooks for allied health majors classes are primarily content-driven and do not include substantial amounts of experimental data in the form of graphs and figures.  In a lower-division allied health majors microbiology class, students were exposed to data from primary journal articles as take-home assignments and their data analysis skills were assessed in a pre-/posttest format.  Students were given 3 assignments that included data analysis questions.  Assignments ranged from case studies that included a figure from a journal article to reading a short journal article and answering questions about multiple figures or tables.  Data were represented as line or bar graphs, gel photographs, and flow charts.  The pre- and posttest was designed incorporating the same types of figures to assess whether the assignments resulted in any improvement in data analysis skills.  The mean class score showed a small but significant improvement from the pretest to the posttest across three semesters of testing.  Scores on individual questions testing accurate conclusions and predictions improved the most.  This supports the conclusion that a relatively small number of out-of-class assignments through the semester resulted in a significant improvement in data analysis abilities in this population of students.

Automated solid-state NMR resonance assignment of protein microcrystals and amyloids

International Nuclear Information System (INIS)

Schmidt, Elena; Gath, Julia; Habenstein, Birgit; Ravotti, Francesco; Székely, Kathrin; Huber, Matthias; Buchner, Lena; Böckmann, Anja; Meier, Beat H.; Güntert, Peter

2013-01-01

Solid-state NMR is an emerging structure determination technique for crystalline and non-crystalline protein assemblies, e.g., amyloids. Resonance assignment constitutes the first and often very time-consuming step to a structure. We present ssFLYA, a generally applicable algorithm for automatic assignment of protein solid-state NMR spectra. Application to microcrystals of ubiquitin and the Ure2 prion C-terminal domain, as well as amyloids of HET-s(218–289) and α-synuclein yielded 88–97 % correctness for the backbone and side-chain assignments that are classified as self-consistent by the algorithm, and 77–90 % correctness if also assignments classified as tentative by the algorithm are included

Preparation of a continuative brochure as supplement to the evaluation hand-out for the assessment of study results; Erstellung einer weiterfuehrenden Broschuere als Ergaenzung zur Handreichung der Beurteilung von Studienergebnissen

Energy Technology Data Exchange (ETDEWEB)

Wilhelmy, S.; Gollnick, F.; Driessen, S.; Schmidt, M.; Gross, D.

2015-08-15

In 2013 the Federal Office for Radiation Protection gave the responsibility to the Department of History, Philosophy and Ethics of Medicine (Institut GTE Med) in Aachen for the project ''Creating a practical hand-out for the assessment of study results for employees of local governments'' (FM 8855). The manual serves as a practical way for the qualitative evaluation of texts for persons who deal with the topics Mobile Communication and Health (for example communities or government agencies) in their profession. The main objective of the manual is to aid users in performing a faster and more efficient evaluation of texts by answering the containing questions. This approach is purely functional and precludes the placement of deeper information. At this point the new project FM 8862 started by ''Creating a continuative brochure in addition to the hand-out for the assessment of study results''. It continued the previous project FM 8855 to further develop the information which was up to this point purely functional. The brochure presents the issues in an overall context and provides valuable background knowledge. As a result, possible users get in a more casual and clear manner a deeper understanding of the evaluating of texts. It should be possible for a user to better evaluate texts and by obtaining arguments, thus being better prepared to engage with interested Laymen in an objective discussion. The brochure was submitted together with the existing manual for a practical test, which was attended by 21 target group-specific subjects. The study tested in detail the intelligibility, clarity, applicability, and the support of the brochure. The feedback of the test participants were then used as basis for the final optimization of the brochure. Project participants belong to the Department of History, Philosophy and Ethics of Medicine and the Research Center for Bioelectromagnetic Interaction of the RWTH Aachen University (femu).

Using HL7 in hospital staff assignments.

Science.gov (United States)

Unluturk, Mehmet S

2014-02-01

Hospital staff assignments are the instructions that allocate the hospital staff members to the hospital beds. Currently, hospital administrators make the assignments without accessing the information regarding the occupancy of the hospital beds and the acuity of the patient. As a result, administrators cannot distinguish between occupied and unoccupied beds, and may therefore assign staff to unoccupied beds. This gives rise to uneven and inefficient staff assignments. In this paper, the hospital admission-discharge-transfer (ADT) system is employed both as a data source and an assignment device to create staff assignments. When the patient data is newly added or modified, the ADT system updates the assignment software client with the relevant data. Based on the relevant data, the assignment software client is able to construct staff assignments in a more efficient way. © 2013 Elsevier Ltd. All rights reserved.

RNA-PAIRS: RNA probabilistic assignment of imino resonance shifts

International Nuclear Information System (INIS)

Bahrami, Arash; Clos, Lawrence J.; Markley, John L.; Butcher, Samuel E.; Eghbalnia, Hamid R.

2012-01-01

The significant biological role of RNA has further highlighted the need for improving the accuracy, efficiency and the reach of methods for investigating RNA structure and function. Nuclear magnetic resonance (NMR) spectroscopy is vital to furthering the goals of RNA structural biology because of its distinctive capabilities. However, the dispersion pattern in the NMR spectra of RNA makes automated resonance assignment, a key step in NMR investigation of biomolecules, remarkably challenging. Herein we present RNA Probabilistic Assignment of Imino Resonance Shifts (RNA-PAIRS), a method for the automated assignment of RNA imino resonances with synchronized verification and correction of predicted secondary structure. RNA-PAIRS represents an advance in modeling the assignment paradigm because it seeds the probabilistic network for assignment with experimental NMR data, and predicted RNA secondary structure, simultaneously and from the start. Subsequently, RNA-PAIRS sets in motion a dynamic network that reverberates between predictions and experimental evidence in order to reconcile and rectify resonance assignments and secondary structure information. The procedure is halted when assignments and base-parings are deemed to be most consistent with observed crosspeaks. The current implementation of RNA-PAIRS uses an initial peak list derived from proton-nitrogen heteronuclear multiple quantum correlation ( 1 H– 15 N 2D HMQC) and proton–proton nuclear Overhauser enhancement spectroscopy ( 1 H– 1 H 2D NOESY) experiments. We have evaluated the performance of RNA-PAIRS by using it to analyze NMR datasets from 26 previously studied RNAs, including a 111-nucleotide complex. For moderately sized RNA molecules, and over a range of comparatively complex structural motifs, the average assignment accuracy exceeds 90%, while the average base pair prediction accuracy exceeded 93%. RNA-PAIRS yielded accurate assignments and base pairings consistent with imino resonances for a

RNA-PAIRS: RNA probabilistic assignment of imino resonance shifts

Energy Technology Data Exchange (ETDEWEB)

Bahrami, Arash; Clos, Lawrence J.; Markley, John L.; Butcher, Samuel E. [National Magnetic Resonance Facility at Madison (United States); Eghbalnia, Hamid R., E-mail: eghbalhd@uc.edu [University of Cincinnati, Department of Molecular and Cellular Physiology (United States)

2012-04-15

The significant biological role of RNA has further highlighted the need for improving the accuracy, efficiency and the reach of methods for investigating RNA structure and function. Nuclear magnetic resonance (NMR) spectroscopy is vital to furthering the goals of RNA structural biology because of its distinctive capabilities. However, the dispersion pattern in the NMR spectra of RNA makes automated resonance assignment, a key step in NMR investigation of biomolecules, remarkably challenging. Herein we present RNA Probabilistic Assignment of Imino Resonance Shifts (RNA-PAIRS), a method for the automated assignment of RNA imino resonances with synchronized verification and correction of predicted secondary structure. RNA-PAIRS represents an advance in modeling the assignment paradigm because it seeds the probabilistic network for assignment with experimental NMR data, and predicted RNA secondary structure, simultaneously and from the start. Subsequently, RNA-PAIRS sets in motion a dynamic network that reverberates between predictions and experimental evidence in order to reconcile and rectify resonance assignments and secondary structure information. The procedure is halted when assignments and base-parings are deemed to be most consistent with observed crosspeaks. The current implementation of RNA-PAIRS uses an initial peak list derived from proton-nitrogen heteronuclear multiple quantum correlation ({sup 1}H-{sup 15}N 2D HMQC) and proton-proton nuclear Overhauser enhancement spectroscopy ({sup 1}H-{sup 1}H 2D NOESY) experiments. We have evaluated the performance of RNA-PAIRS by using it to analyze NMR datasets from 26 previously studied RNAs, including a 111-nucleotide complex. For moderately sized RNA molecules, and over a range of comparatively complex structural motifs, the average assignment accuracy exceeds 90%, while the average base pair prediction accuracy exceeded 93%. RNA-PAIRS yielded accurate assignments and base pairings consistent with imino

Smartnotebook: A semi-automated approach to protein sequential NMR resonance assignments

International Nuclear Information System (INIS)

Slupsky, Carolyn M.; Boyko, Robert F.; Booth, Valerie K.; Sykes, Brian D.

2003-01-01

Complete and accurate NMR spectral assignment is a prerequisite for high-throughput automated structure determination of biological macromolecules. However, completely automated assignment procedures generally encounter difficulties for all but the most ideal data sets. Sources of these problems include difficulty in resolving correlations in crowded spectral regions, as well as complications arising from dynamics, such as weak or missing peaks, or atoms exhibiting more than one peak due to exchange phenomena. Smartnotebook is a semi-automated assignment software package designed to combine the best features of the automated and manual approaches. The software finds and displays potential connections between residues, while the spectroscopist makes decisions on which connection is correct, allowing rapid and robust assignment. In addition, smartnotebook helps the user fit chains of connected residues to the primary sequence of the protein by comparing the experimentally determined chemical shifts with expected shifts derived from a chemical shift database, while providing bookkeeping throughout the assignment procedure

Work assignments, delegation of tasks and job satisfaction among Danish dental hygienists.

Science.gov (United States)

Hach, M; Aaberg, K B; Lempert, S M; Danielsen, B

2017-08-01

Recent legislation in Denmark has made it possible for dentists to delegate their tasks to dental hygienists. Previous studies have shown that Danish dental hygienists primarily were performing assignments within their own work field. These assignments include prophylaxis or instructing patients in oral health care. However, studies have also shown that Danish dental hygienists performed dental nurse assignments such as chair-side assistance, unit cleaning and disinfection of instruments. The objectives of this study were to investigate (i) the range of work assignments performed by Danish dental hygienists, (ii) the types of dentist tasks performed by Danish dental hygienists and (iii) job satisfaction among Danish dental hygienists. Dental hygienists graduating in 2004-2007 were invited to participate in this study. Participants answered an email-distributed questionnaire. The questionnaire consisted of questions regarding job satisfaction, assignments performed, postgraduate course attendance, receiving assistance from a dental nurse and which work assignments Danish dental hygienists wish to perform in the future. The results of this study showed that 90% of Danish dental hygienists were satisfied with their job and 52% were performing dentists' tasks. Among dentists' tasks performed by Danish dental hygienists, invasive caries therapy was the most frequently performed task. The type of assignments performed by Danish dental hygienists today appears to be changing compared to previous studies. From initially performing prophylaxis and chair-side assistance for the dentist, Danish dental hygienists today are performing a wider range of tasks which includes dentists' tasks. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

A note on ranking assignments using reoptimization

DEFF Research Database (Denmark)

Pedersen, Christian Roed; Nielsen, L.R.; Andersen, K.A.

2005-01-01

We consider the problem of ranking assignments according to cost in the classical linear assignment problem. An algorithm partitioning the set of possible assignments, as suggested by Murty, is presented where, for each partition, the optimal assignment is calculated using a new reoptimization...

Competitive Traffic Assignment in Road Networks

Directory of Open Access Journals (Sweden)

Krylatov Alexander Y.

2016-09-01

Full Text Available Recently in-vehicle route guidance and information systems are rapidly developing. Such systems are expected to reduce congestion in an urban traffic area. This social benefit is believed to be reached by imposing the route choices on the network users that lead to the system optimum traffic assignment. However, guidance service could be offered by different competitive business companies. Then route choices of different mutually independent groups of users may reject traffic assignment from the system optimum state. In this paper, a game theoretic approach is shown to be very efficient to formalize competitive traffic assignment problem with various groups of users in the form of non-cooperative network game with the Nash equilibrium search. The relationships between the Wardrop’s system optimum associated with the traffic assignment problem and the Nash equilibrium associated with the competitive traffic assignment problem are investigated. Moreover, some related aspects of the Nash equilibrium and the Wardrop’s user equilibrium assignments are also discussed.

Illustrations and supporting texts for sound standing waves of air columns in pipes in introductory physics textbooks

Directory of Open Access Journals (Sweden)

Liang Zeng

2014-07-01

Full Text Available In our pilot studies, we found that many introductory physics textbook illustrations with supporting text for sound standing waves of air columns in open-open, open-closed, and closed-closed pipes inhibit student understanding of sound standing wave phenomena due to student misunderstanding of how air molecules move within these pipes. Based on the construct of meaningful learning from cognitive psychology and semiotics, a quasiexperimental study was conducted to investigate the comparative effectiveness of two alternative approaches to student understanding: a traditional textbook illustration approach versus a newly designed air molecule motion illustration approach. Thirty volunteer students from introductory physics classes were randomly assigned to two groups of 15 each. Both groups were administered a presurvey. Then, group A read the air molecule motion illustration handout, and group B read a traditional textbook illustration handout; both groups were administered postsurveys. Subsequently, the procedure was reversed: group B read the air molecule motion illustration handout and group A read the traditional textbook illustration handout. This was followed by a second postsurvey along with an exit research questionnaire. The study found that the majority of students experienced meaningful learning and stated that they understood sound standing wave phenomena significantly better using the air molecule motion illustration approach. This finding provides a method for physics education researchers to design illustrations for abstract sound standing wave concepts, for publishers to improve their illustrations with supporting text, and for instructors to facilitate deeper learning in their students on sound standing waves.

Real life working shift assignment problem

Science.gov (United States)

Sze, San-Nah; Kwek, Yeek-Ling; Tiong, Wei-King; Chiew, Kang-Leng

2017-07-01

This study concerns about the working shift assignment in an outlet of Supermarket X in Eastern Mall, Kuching. The working shift assignment needs to be solved at least once in every month. Current approval process of working shifts is too troublesome and time-consuming. Furthermore, the management staff cannot have an overview of manpower and working shift schedule. Thus, the aim of this study is to develop working shift assignment simulation and propose a working shift assignment solution. The main objective for this study is to fulfill manpower demand at minimum operation cost. Besides, the day off and meal break policy should be fulfilled accordingly. Demand based heuristic is proposed to assign working shift and the quality of the solution is evaluated by using the real data.

24 CFR 221.770 - Assignment option.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.770 Section... § 221.770 Assignment option. A mortgagee holding a conditional or firm commitment issued on or before... mortgagee's approved underwriter on or before November 30, 1983) has the option to assign, transfer and...

Job Assignments under Moral Hazard

DEFF Research Database (Denmark)

Koch, Alexander; Nafziger, Julia

Inefficient job assignments are usually explained with incomplete information about employees' abilities or contractual imperfections. We show that inefficient assignments arise even without uncertainty about the employee's ability and with complete contracts. Building on this result we provide...

EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data

Energy Technology Data Exchange (ETDEWEB)

Zuiderweg, Erik R. P., E-mail: zuiderwe@umich.edu; Bagai, Ireena [The University of Michigan Medical School, Department of Biological Chemistry (United States); Rossi, Paolo [Rutgers University, Center for Integrative Proteomics Research (United States); Bertelsen, Eric B. [Arbor Communications, Inc. (United States)

2013-10-15

For several of the proteins in the BioMagResBank larger than 200 residues, 60 % or fewer of the backbone resonances were assigned. But how reliable are those assignments? In contrast to complete assignments, where it is possible to check whether every triple-resonance Generalized Spin System (GSS) is assigned once and only once, with incomplete data one should compare all possible assignments and pick the best one. But that is not feasible: For example, for 200 residues and an incomplete set of 100 GSS, there are 1.6 Multiplication-Sign 10{sup 260} possible assignments. In 'EZ-ASSIGN', the protein sequence is divided in smaller unique fragments. Combined with intelligent search approaches, an exhaustive comparison of all possible assignments is now feasible using a laptop computer. The program was tested with experimental data of a 388-residue domain of the Hsp70 chaperone protein DnaK and for a 351-residue domain of a type III secretion ATPase. EZ-ASSIGN reproduced the hand assignments. It did slightly better than the computer program PINE (Bahrami et al. in PLoS Comput Biol 5(3):e1000307, 2009) and significantly outperformed SAGA (Crippen et al. in J Biomol NMR 46:281-298, 2010), AUTOASSIGN (Zimmerman et al. in J Mol Biol 269:592-610, 1997), and IBIS (Hyberts and Wagner in J Biomol NMR 26:335-344, 2003). Next, EZ-ASSIGN was used to investigate how well NMR data of decreasing completeness can be assigned. We found that the program could confidently assign fragments in very incomplete data. Here, EZ-ASSIGN dramatically outperformed all the other assignment programs tested.

Socially-assigned race, healthcare discrimination and preventive healthcare services.

Directory of Open Access Journals (Sweden)

Tracy Macintosh

Full Text Available Race and ethnicity, typically defined as how individuals self-identify, are complex social constructs. Self-identified racial/ethnic minorities are less likely to receive preventive care and more likely to report healthcare discrimination than self-identified non-Hispanic whites. However, beyond self-identification, these outcomes may vary depending on whether racial/ethnic minorities are perceived by others as being minority or white; this perception is referred to as socially-assigned race.To examine the associations between socially-assigned race and healthcare discrimination and receipt of selected preventive services.Cross-sectional analysis of the 2004 Behavioral Risk Factor Surveillance System "Reactions to Race" module. Respondents from seven states and the District of Columbia were categorized into 3 groups, defined by a composite of self-identified race/socially-assigned race: Minority/Minority (M/M, n = 6,837, Minority/White (M/W, n = 929, and White/White (W/W, n = 25,913. Respondents were 18 years or older, with 61.7% under age 60; 51.8% of respondents were female. Measures included reported healthcare discrimination and receipt of vaccinations and cancer screenings.Racial/ethnic minorities who reported being socially-assigned as minority (M/M were more likely to report healthcare discrimination compared with those who reported being socially-assigned as white (M/W (8.9% vs. 5.0%, p = 0.002. Those reporting being socially-assigned as white (M/W and W/W had similar rates for past-year influenza (73.1% vs. 74.3% and pneumococcal (69.3% vs. 58.6% vaccinations; however, rates were significantly lower among M/M respondents (56.2% and 47.6%, respectively, p-values<0.05. There were no significant differences between the M/M and M/W groups in the receipt of cancer screenings.Racial/ethnic minorities who reported being socially-assigned as white are more likely to receive preventive vaccinations and less likely to report

24 CFR 221.255 - Assignment option.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.255 Section... Assignment option. (a) A mortgagee holding a mortgage insured pursuant to a conditional or firm commitment issued on or before November 30, 1983 has the option to assign, transfer and deliver to the Commissioner...

An algorithm for ranking assignments using reoptimization

DEFF Research Database (Denmark)

Pedersen, Christian Roed; Nielsen, Lars Relund; Andersen, Kim Allan

2008-01-01

We consider the problem of ranking assignments according to cost in the classical linear assignment problem. An algorithm partitioning the set of possible assignments, as suggested by Murty, is presented where, for each partition, the optimal assignment is calculated using a new reoptimization...... technique. Computational results for the new algorithm are presented...

48 CFR 42.602 - Assignment and location.

Science.gov (United States)

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Assignment and location... Assignment and location. (a) A CACO may be assigned only when (1) the contractor has at least two locations..., or a full-time CACO may be assigned. In determining the location of the CACO, the responsible agency...

Interactive Level Design for iOS Assignment Delivery: A Case Study

Directory of Open Access Journals (Sweden)

Anson Brown

2014-02-01

Full Text Available This paper presents an application of an iOS-based online gaming assignment in a real classroom. The core concept of the project is a gameplay environment involving two players that have full control over creation and modification of levels. This level design mechanism was implemented in an iOS-based game in the area of genetics and based on an existing written assignment. The game includes support for both instructors, who have the ability to create and post assignments and students, who can take the assignments. Two trials of the iOS application consisted of in-class testing of twenty- one students. Students first took the original paper assignment, followed by the iOS version. Start times, end times, and grades were recorded for both versions. A comprehensive study of the grades and times for the iOS version of the assignment versus the paper version was conducted and is presented in this paper. Our Study showed that the iOS version was completed much faster in nearly every case while a strong delivery mechanism is needed to ensure student grades and completion of the assignment will not be affected. These results are not unexpected due to some major difference between the two formats. Future updates and additions will address any currently existing issues.

EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data

International Nuclear Information System (INIS)

Zuiderweg, Erik R. P.; Bagai, Ireena; Rossi, Paolo; Bertelsen, Eric B.

2013-01-01

For several of the proteins in the BioMagResBank larger than 200 residues, 60 % or fewer of the backbone resonances were assigned. But how reliable are those assignments? In contrast to complete assignments, where it is possible to check whether every triple-resonance Generalized Spin System (GSS) is assigned once and only once, with incomplete data one should compare all possible assignments and pick the best one. But that is not feasible: For example, for 200 residues and an incomplete set of 100 GSS, there are 1.6 × 10 260 possible assignments. In “EZ-ASSIGN”, the protein sequence is divided in smaller unique fragments. Combined with intelligent search approaches, an exhaustive comparison of all possible assignments is now feasible using a laptop computer. The program was tested with experimental data of a 388-residue domain of the Hsp70 chaperone protein DnaK and for a 351-residue domain of a type III secretion ATPase. EZ-ASSIGN reproduced the hand assignments. It did slightly better than the computer program PINE (Bahrami et al. in PLoS Comput Biol 5(3):e1000307, 2009) and significantly outperformed SAGA (Crippen et al. in J Biomol NMR 46:281–298, 2010), AUTOASSIGN (Zimmerman et al. in J Mol Biol 269:592–610, 1997), and IBIS (Hyberts and Wagner in J Biomol NMR 26:335–344, 2003). Next, EZ-ASSIGN was used to investigate how well NMR data of decreasing completeness can be assigned. We found that the program could confidently assign fragments in very incomplete data. Here, EZ-ASSIGN dramatically outperformed all the other assignment programs tested

Automatic Assignment of Methyl-NMR Spectra of Supramolecular Machines Using Graph Theory.

Science.gov (United States)

Pritišanac, Iva; Degiacomi, Matteo T; Alderson, T Reid; Carneiro, Marta G; Ab, Eiso; Siegal, Gregg; Baldwin, Andrew J

2017-07-19

Methyl groups are powerful probes for the analysis of structure, dynamics and function of supramolecular assemblies, using both solution- and solid-state NMR. Widespread application of the methodology has been limited due to the challenges associated with assigning spectral resonances to specific locations within a biomolecule. Here, we present Methyl Assignment by Graph Matching (MAGMA), for the automatic assignment of methyl resonances. A graph matching protocol examines all possibilities for each resonance in order to determine an exact assignment that includes a complete description of any ambiguity. MAGMA gives 100% accuracy in confident assignments when tested against both synthetic data, and 9 cross-validated examples using both solution- and solid-state NMR data. We show that this remarkable accuracy enables a user to distinguish between alternative protein structures. In a drug discovery application on HSP90, we show the method can rapidly and efficiently distinguish between possible ligand binding modes. By providing an exact and robust solution to methyl resonance assignment, MAGMA can facilitate significantly accelerated studies of supramolecular machines using methyl-based NMR spectroscopy.

Effects of three types of lecture notes on medical student achievement.

Science.gov (United States)

Russell, I J; Caris, T N; Harris, G D; Hendricson, W D

1983-08-01

Two parallel studies were conducted with junior medical students to determine what influence the forms of lecture notes would have on learning. The three types of notes given to the students were: a comprehensive manuscript of the lecture containing text, tables, and figures; a partial handout which included some illustrations but required substantial annotation by the students; and a skeleton outline containing no data from the lecture. The students' knowledge about the subject was measured before the lecture, immediately after the lecture, two to four weeks later, and approximately three months later. The students' responses to questionnaires indicated a strong preference for very detained handouts as essential to preparation for examinations. By contract, the students' performances on tests generally were better for those who had received the partial or skeleton handout formats. This was particularly true for information presented during the last quarter of each lecture, when learning efficiency of the skeleton handout group increased while the other two handout groups exhibited learning fatigue. It was concluded that learning by medical students was improved when they recorded notes in class.

Consistent assignment of nursing staff to residents in nursing homes: a critical review of conceptual and methodological issues.

Science.gov (United States)

Roberts, Tonya; Nolet, Kimberly; Bowers, Barbara

2015-06-01

Consistent assignment of nursing staff to residents is promoted by a number of national organizations as a strategy for improving nursing home quality and is included in pay for performance schedules in several states. However, research has shown inconsistent effects of consistent assignment on quality outcomes. In order to advance the state of the science of research on consistent assignment and inform current practice and policy, a literature review was conducted to critique conceptual and methodological understandings of consistent assignment. Twenty original research reports of consistent assignment in nursing homes were found through a variety of search strategies. Consistent assignment was conceptualized and operationalized in multiple ways with little overlap from study to study. There was a lack of established methods to measure consistent assignment. Methodological limitations included a lack of control and statistical analyses of group differences in experimental-level studies, small sample sizes, lack of attention to confounds in multicomponent interventions, and outcomes that were not theoretically linked. Future research should focus on developing a conceptual understanding of consistent assignment focused on definition, measurement, and links to outcomes. To inform current policies, testing consistent assignment should include attention to contexts within and levels at which it is most effective. Published by Oxford University Press on behalf of the Gerontological Society of America 2013.

Exogenous spatial attention influences figure-ground assignment.

Science.gov (United States)

Vecera, Shaun P; Flevaris, Anastasia V; Filapek, Joseph C

2004-01-01

In a hierarchical stage account of vision, figure-ground assignment is thought to be completed before the operation of focal spatial attention. Results of previous studies have supported this account by showing that unpredictive, exogenous spatial precues do not influence figure-ground assignment, although voluntary attention can influence figure-ground assignment. However, in these studies, attention was not summoned directly to a region in a figure-ground display. In three experiments, we addressed the relationship between figure-ground assignment and visuospatial attention. In Experiment 1, we replicated the finding that exogenous precues do not influence figure-ground assignment when they direct attention outside of a figure-ground stimulus. In Experiment 2, we demonstrated that exogenous attention can influence figure-ground assignment if it is directed to one of the regions in a figure-ground stimulus. In Experiment 3, we demonstrated that exogenous attention can influence figure-ground assignment in displays that contain a Gestalt figure-ground cue; this result suggests that figure-ground processes are not entirely completed prior to the operation of focal spatial attention. Exogenous spatial attention acts as a cue for figure-ground assignment and can affect the outcome of figure-ground processes.

WebAssign: Assessing Your Students' Understanding Continuously

Science.gov (United States)

Risley, John S.

1999-11-01

Motivating students to learn is a constant challenge for faculty. Technology can play a significant role. One such solution is WebAssign — a web-based homework system that offers new teaching and learning opportunities for educators and their students. WebAssign delivers, collects, grades, and records customized homework assignments over the Internet. Students get immediate feedback with credit and instructors can implement "Just-in-Time" teaching. In this talk, I will describe how assignments can be generated with different numerical values for each question, giving each student a unique problem to solve. This feature encourages independent thinking with the benefit of collaborative learning. Example assignments taken from textbook questions and intellectually engaging Java applet simulations will be shown. Studies and first-hand experience on the educational impact of using WebAssign will also be discussed.

Reflective practice: assessment of assignments in English for Specific Purposes

Directory of Open Access Journals (Sweden)

Galina Kavaliauskiené

2007-10-01

Full Text Available The construct alternative assessment has been widely used in higher education. It is often defined as any type of assessment of learners who provide a response to an assignment. The key features of alternative assessment are active participation of learners in self-evaluation of their performance, and the development of reflective thinking through reflective thinking (Schön, 1983. The success of alternative assessment in language teaching is predetermined by student’s performance and demonstrates learner’s language proficiency in contemporary communicative classrooms. This paper aims at researching the influence of students’ evaluations of various assignments for their linguistic development in English for Specific Purposes (ESP. The study uses learners’ assessment of different assignments and learners’ in-course and post-course written reflections on benefits to language mastery. Learners’ assignments included were contributions to portfolios (dossiers, such as essays and summaries, oral presentations, short impromptu talks, creative tasks, tests, and self-assessment notes (reflections on activities in learning ESP. Findings were obtained for two streams of the project participants. Results showed that self-assessment was beneficial for learners’ linguistic development. The context of learners’ reflections reveals that the attitudes to various assignments are affected by success or failure in students’ performance. Reflective practice might help teachers develop ways of dealing with previously identified difficulties and improve the quality of teaching.

Hand-out: SFOE research conference on traffic technology and accumulators; Handout BFE-Forschungstagung Technologiebereich Verkehr Technologiebereich Akkumulatoren

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-07-01

This comprehensive collection contains presentation slides presented at a research conference organised by the Swiss Federal Office of Energy (SFOE) at the Federal Institute of Science and Technology in Zurich in February 2004. Apart from two presentations on the future of the 'SwissEnergy' programme and research in the EU, fifteen further presentations are included. These cover the 'Cleaner Drive' project, the influence of lightweight electric vehicles on mobility behaviour, the advantages of 'EcoDrive' in the year 2010, results of a study on 'park-and-ride' facilities, the CO{sub 2}-effect, innovation, the possibilities offered by S-Cap capacitors and 'Sun Fuels'. Further contributions include the 'Downhill Coaster', weather-protection for bicycles, natural-gas fuelled buses, the operation of an Otto-motor using a petrol / natural gas / reformer gas mix, usage and optimisation of the 'Zebra' battery, innovative vehicles for the 'Novatlantis'-pilot region in Basle and a contribution on climate protection in the aviation area.

Solving the rectangular assignment problem and applications

NARCIS (Netherlands)

Bijsterbosch, J.; Volgenant, A.

2010-01-01

The rectangular assignment problem is a generalization of the linear assignment problem (LAP): one wants to assign a number of persons to a smaller number of jobs, minimizing the total corresponding costs. Applications are, e.g., in the fields of object recognition and scheduling. Further, we show

7 CFR 900.106 - Assignment of mediator.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Assignment of mediator. 900.106 Section 900.106 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Assignment of mediator. The Director of the Division shall assign a mediator, from the group designated by...

My Favorite Assignment.

Science.gov (United States)

ABCA Bulletin, 1983

1983-01-01

Describes three assignments for enticing business communication students to undertake library research: an analysis of a Fortune 500 company, a career choice report, and a report on an organization that offers potential employment. (AEA)

Strategies to Support PGCE Mathematics and Science Students Preparing for Assignments at Masters Level

OpenAIRE

Tas, Maarten; Forsythe, Sue

2010-01-01

The main aim of this study was to analyse and evaluate the effectiveness of support strategies being put into place for students who need to write assignments at Masters Level. In preparation for writing a 5000 word assignment on an aspect of teaching Mathematics or Science, 57 Science and Mathematics PGCE students were asked to write a 500 word synopsis which included an introduction, description of the main focus, questions that the assignment would address and possible strategies for teach...

Target assignment for security officers to K targets (TASK)

International Nuclear Information System (INIS)

Rowland, J.R.; Shelton, K.W.; Stunkel, C.B.

1983-02-01

A probabilistic algorithm is developed to provide an optimal Target Assignment for Security officers to K targets (TASK) using a maximin criterion. Under the assumption of only a limited number (N) of security officers, the TASK computer model determines deployment assignments which maximize the system protection against sabotage by an adversary who may select any link in the system, including the weakest, for the point of attack. Applying the TASK model to a hypothetical nuclear facility containing a nine-level building reveals that aggregate targets covering multiple vital areas should be utilized to reduce the number of possible target assignments to a value equal to or only slightly larger than N. The increased probability that a given aggregate target is covered by one or more security officers offsets the slight decrease in interruption probability due to its occurring earlier in the adversary's path. In brief, the TASK model determines the optimal maximin deployment strategy for limited numbers of security officers and calculates a quantitative measure of the resulting system protection

Managing voluntary turnover through challenging assignments

NARCIS (Netherlands)

Preenen, P.T.Y.; de Pater, I.E.; van Vianen, A.E.M.; Keijzer, L.

2011-01-01

This study examines employees’ challenging assignments as manageable means to reduce turnover intentions, job search behaviors, and voluntary turnover. Results indicate that challenging assignments are negatively related to turnover intentions and job search behaviors and that these relationships

Managing voluntary turnover through challenging assignments

NARCIS (Netherlands)

Preenen, P.T.Y.; Pater, I.E. de; Vianen, A.E.M. van; Keijzer, L.

2011-01-01

This study examines employees' challenging assignments as manageable means to reduce turnover intentions, job search behaviors, and voluntary turnover. Results indicate that challenging assignments are negatively related to turnover intentions and job search behaviors and that these relationships

An Accurate and Impartial Expert Assignment Method for Scientific Project Review

Directory of Open Access Journals (Sweden)

Mingliang Yue

2017-12-01

Full Text Available Purpose: This paper proposes an expert assignment method for scientific project review that considers both accuracy and impartiality. As impartial and accurate peer review is extremely important to ensure the quality and feasibility of scientific projects, enhanced methods for managing the process are needed. Design/methodology/approach: To ensure both accuracy and impartiality, we design four criteria, the reviewers’ fitness degree, research intensity, academic association, and potential conflict of interest, to express the characteristics of an appropriate peer review expert. We first formalize the expert assignment problem as an optimization problem based on the designed criteria, and then propose a randomized algorithm to solve the expert assignment problem of identifying reviewer adequacy. Findings: Simulation results show that the proposed method is quite accurate and impartial during expert assignment. Research limitations: Although the criteria used in this paper can properly show the characteristics of a good and appropriate peer review expert, more criteria/conditions can be included in the proposed scheme to further enhance accuracy and impartiality of the expert assignment. Practical implications: The proposed method can help project funding agencies (e.g. the National Natural Science Foundation of China find better experts for project peer review. Originality/value: To the authors’ knowledge, this is the first publication that proposes an algorithm that applies an impartial approach to the project review expert assignment process. The simulation results show the effectiveness of the proposed method.

Accuracy of administratively-assigned ancestry for diverse populations in an electronic medical record-linked biobank.

Directory of Open Access Journals (Sweden)

Jacob B Hall

Full Text Available Recently, the development of biobanks linked to electronic medical records has presented new opportunities for genetic and epidemiological research. Studies based on these resources, however, present unique challenges, including the accurate assignment of individual-level population ancestry. In this work we examine the accuracy of administratively-assigned race in diverse populations by comparing assigned races to genetically-defined ancestry estimates. Using 220 ancestry informative markers, we generated principal components for patients in our dataset, which were used to cluster patients into groups based on genetic ancestry. Consistent with other studies, we find a strong overall agreement (Kappa  = 0.872 between genetic ancestry and assigned race, with higher rates of agreement for African-descent and European-descent assignments, and reduced agreement for Hispanic, East Asian-descent, and South Asian-descent assignments. These results suggest caution when selecting study samples of non-African and non-European backgrounds when administratively-assigned race from biobanks is used.

Scaffolding students’ assignments

DEFF Research Database (Denmark)

Slot, Marie Falkesgaard

2013-01-01

This article discusses scaffolding in typical student assignments in mother tongue learning materials in upper secondary education in Denmark and the United Kingdom. It has been determined that assignments do not have sufficient scaffolding end features to help pupils understand concepts and build...... objects. The article presents the results of empirical research on tasks given in Danish and British learning materials. This work is based on a further development of my PhD thesis: “Learning materials in the subject of Danish” (Slot 2010). The main focus is how cognitive models (and subsidiary explicit...... learning goals) can help students structure their argumentative and communica-tive learning processes, and how various multimodal representations can give more open-ended learning possibilities for collaboration. The article presents a short introduction of the skills for 21st century learning and defines...

A Comparative Analysis of Pair-work and Individual Assignments In two ELT Grammar Classes

Directory of Open Access Journals (Sweden)

Olcay Sert

2005-10-01

Full Text Available Assignments prepared in pair-work have long been evaluated to be more successful whencompared to individually prepared assignments in many respects in foreign language learningcontexts. However, there is not much research conducted to reveal the advantages of pair-work in preparing assignments and the linguistic characteristics of the finished texts. In this paper, depending upon an experimental study with the first year students in Department of EnglishLanguage Teaching at Hacettepe University, quality of pair-work assignments and the factors affecting the preparation process are discussed and compared to individual assignments. Results indicate a variety of advantages of student collaboration in preparing written work since outputsare far more grammatical, include less spelling mistakes, and indicate a higher level ofgrammatical awareness. Additionally, pair-work helps students build positive interpersonalrelationships and create a high level of academic solidarity and confidence.

Inferential backbone assignment for sparse data

International Nuclear Information System (INIS)

Vitek, Olga; Bailey-Kellogg, Chris; Craig, Bruce; Vitek, Jan

2006-01-01

This paper develops an approach to protein backbone NMR assignment that effectively assigns large proteins while using limited sets of triple-resonance experiments. Our approach handles proteins with large fractions of missing data and many ambiguous pairs of pseudoresidues, and provides a statistical assessment of confidence in global and position-specific assignments. The approach is tested on an extensive set of experimental and synthetic data of up to 723 residues, with match tolerances of up to 0.5 ppm for C α and C β resonance types. The tests show that the approach is particularly helpful when data contain experimental noise and require large match tolerances. The keys to the approach are an empirical Bayesian probability model that rigorously accounts for uncertainty in the data at all stages in the analysis, and a hybrid stochastic tree-based search algorithm that effectively explores the large space of possible assignments

An analysis of project selection and assignment criteria of Danish tenders in Europe

Directory of Open Access Journals (Sweden)

Jasper Kranker Larsen

2013-12-01

Full Text Available Public construction agencies are one of the largest developers within the Danish construction industry, where such agencies own and develop new public construction projects. Most of these projects are put out in European tender. This study analyses the selection and assignment criteria employed by these agencies in different types of public sector projects. Some of the objectives pursued by the study include the determination of 1/ the selection and assignment criteria mostly used in Danish public tenders 2/ how different types of projects use selection and assignment criteria in the bidding process, and 3/ any significant difference between the use of selection and assignment criteria in Danish public construction projects. The study uses a quantitative research approach where 157 Danish public tender cases were selected from the European Tenders Electronic Daily database between the period: January 2010 to March 2013. Fisher's Exact Test was conducted to determine if there was any significant use of some selection and assignment criteria. The findings of the study showed that invited tenders with pre-qualification and lowest price in 69.8% of the tenders are the most used selection and assignment criteria, with little regard to project type.

Use of a verbal electronic audio reminder with a patient hand hygiene bundle to increase independent patient hand hygiene practices of older adults in an acute care setting.

Science.gov (United States)

Knighton, Shanina C; Dolansky, Mary; Donskey, Curtis; Warner, Camille; Rai, Herleen; Higgins, Patricia A

2018-03-01

We hypothesized that the addition of a novel verbal electronic audio reminder to an educational patient hand hygiene bundle would increase performance of self-managed patient hand hygiene. We conducted a 2-group comparative effectiveness study randomly assigning participants to patient hand hygiene bundle 1 (n = 41), which included a video, a handout, and a personalized verbal electronic audio reminder (EAR) that prompted hand cleansing at 3 meal times, or patient hand hygiene bundle 2 (n = 34), which included the identical video and handout, but not the EAR. The primary outcome was alcohol-based hand sanitizer use based on weighing bottles of hand sanitizer. Participants that received the EAR averaged significantly more use of hand sanitizer product over the 3 days of the study (mean ± SD, 29.97 ± 17.13 g) than participants with no EAR (mean ± SD, 10.88 ± 9.27 g; t 73  = 5.822; P ≤ .001). The addition of a novel verbal EAR to a patient hand hygiene bundle resulted in a significant increase in patient hand hygiene performance. Our results suggest that simple audio technology can be used to improve patient self-management of hand hygiene. Future research is needed to determine if the technology can be used to promote other healthy behaviors, reduce infections, and improve patient-centered care without increasing the workload of health care workers. Published by Elsevier Inc.

Unintended Cognitive, Affective, and Behavioral Consequences of Group Assignments

Science.gov (United States)

Neu, Wayne A.

2012-01-01

Pedagogical strategies can be thought of as a set of stimuli placed in students' environment to influence their cognition, affect, and behavior. The design of strategies such as group assignments and a comprehensive understanding of their consequences for students should then include an analysis of all three of these elements and the…

32 CFR 884.2 - Assigned responsibilities.

Science.gov (United States)

2010-07-01

... OF PERSONNEL TO UNITED STATES CIVILIAN AUTHORITIES FOR TRIAL § 884.2 Assigned responsibilities. (a... 32 National Defense 6 2010-07-01 2010-07-01 false Assigned responsibilities. 884.2 Section 884.2... requests for return of members to the United States for delivery to civilian authorities when the request...

Personnel dose assignment practices

International Nuclear Information System (INIS)

Fix, J.J.

1993-04-01

Implementation of DOE N 5480.6 Radiological Control Manual Article 511(3) requirements, to minimize the assignment of personnel dosimeters, should be done only under a broader context ensuring that capabilities are in place to monitor and record personnel exposure both for compliance and for potential litigation. As noted in NCRP Report No. 114, personnel dosimetry programs are conducted to meet four major objectives: radiation safety program control and evaluation; regulatory compliance; epidemiological research; and litigation. A change to Article 511(3) is proposed that would require that minimizing the assignment of personnel dosimeters take place only following full evaluation of overall capabilities (e.g., access control, area dosimetry, etc.) to meet the NCRP objectives

Computational Aspects of Assigning Agents to a Line

DEFF Research Database (Denmark)

Aziz, Haris; Hougaard, Jens Leth; Moreno-Ternero, Juan D.

2017-01-01

-egalitarian assignments. The approach relies on an algorithm which is shown to be faster than general purpose algorithms for the assignment problem. We also extend the approach to probabilistic assignments and explore the computational features of existing, as well as new, methods for this setting....

Computational aspects of assigning agents to a line

DEFF Research Database (Denmark)

Aziz, Haris; Hougaard, Jens Leth; Moreno-Ternero, Juan D.

2017-01-01

-egalitarian assignments. The approach relies on an algorithm which is shown to be faster than general purpose algorithms for the assignment problem. We also extend the approach to probabilistic assignments and explore the computational features of existing, as well as new, methods for this setting....

A Computerized Approach to Trickle-Process, Random Assignment.

Science.gov (United States)

Braucht, G. Nicholas; Reichardt, Charles S.

1993-01-01

Procedures for implementing random assignment with trickle processing and ways they can be corrupted are described. A computerized method for implementing random assignment with trickle processing is presented as a desirable alternative in many situations and a way of protecting against threats to assignment validity. (SLD)

Writing Assignments that Promote Active Learning

Science.gov (United States)

Narayanan, M.

2014-12-01

Encourage students to write a detailed, analytical report correlating classroom discussions to an important historical event or a current event. Motivate students interview an expert from industry on a topic that was discussed in class. Ask the students to submit a report with supporting sketches, drawings, circuit diagrams and graphs. Propose that the students generate a complete a set of reading responses pertaining to an assigned topic. Require each student to bring in one comment or one question about an assigned reading. The assignment should be a recent publication in an appropriate journal. Have the students conduct a web search on an assigned topic. Ask them to generate a set of ideas that can relate to classroom discussions. Provide the students with a study guide. The study guide should provide about 10 or 15 short topics. Quiz the students on one or two of the topics. Encourage the students to design or develop some creative real-world examples based on a chapter discussed or a topic of interest. Require that students originate, develop, support and defend a viewpoint using a specifically assigned material. Make the students practice using or utilizing a set of new technical terms they have encountered in an assigned chapter. Have students develop original examples explaining the different terms. Ask the students to select one important terminology from the previous classroom discussions. Encourage the students to explain why they selected that particular word. Ask them to talk about the importance of the terminology from the point of view of their educational objectives and future career. Angelo, T. A. (1991). Ten easy pieces: Assessing higher learning in four dimensions. In T. A. Angelo (Ed.), Classroom research: Early lessons from success (pp. 17-31). New Directions for Teaching and Learning, No. 46. San Francisco: Jossey-Bass.

Detecting Plagiarism in MS Access Assignments

Science.gov (United States)

Singh, Anil

2013-01-01

Assurance of individual effort from students in computer-based assignments is a challenge. Due to digitization, students can easily use a copy of their friend's work and submit it as their own. Plagiarism in assignments puts students who cheat at par with those who work honestly and this compromises the learning evaluation process. Using a…

First Trimester Fetal Gender Assignment by Ultrasound

Directory of Open Access Journals (Sweden)

Sabahattin Altunyurt

2010-03-01

Full Text Available Objective: To investigate the efficiency of genital tubercule angle on detecting fetal gender in first trimester by ultrasonography. Material-Method: Fetal sex assignment by ultrasound was carried out in 172 pregnancies at 11-13+6 weeks between 2007 June and 2007 December. Gestational age was determined by the measurement of crown-rump length (CRL. The ultrasound predictions were compared with actual sex at birth. Mid-sagittal planes of a section of the fetal genital tubercle were performed to identify the gender. Results: 155 of 172 patients’ data were achieved. The overall success rate was 92.3 % in sonographic assignment of fetal sex. The correct assignment rate in female fetuses was significantly higher than males (95.9 % - 88.8 % [p=0,001]. The correct identification of fetal sex improved with advancing gestational age from 89.3 % between 11-11+6 weeks, 92.5 % between 12-12+6 weeks and 93.4 % between 13-13+6 weeks (p=0,96. Conclusion: The fetal sex assignment by ultrasonography between 11-13+6 weeks had high success rate. The sensitivity of fetal sex assignment was not affected with fetus position and gestational age.

Historical WBAN ID Assignments

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — 4"x6" index cards represent the first written assignments of Weather Bureau Army Navy (WBAN) station identifier numbers by the National Climatic Data Center....

Manual of functions, assignments, and responsibilities for nuclear safety: Revision 2

Energy Technology Data Exchange (ETDEWEB)

1994-10-15

The FAR Manual is a convenient easy-to-use collection of the functions, assignments, and responsibilities (FARs) of DOE nuclear safety personnel. Current DOE directives, including Orders, Secretary of Energy Notices, and other assorted policy memoranda, are the source of this information and form the basis of the FAR Manual. Today, the majority of FARs for DOE personnel are contained in DOE`s nuclear safety Orders. As these Orders are converted to rules in the Code of Federal Regulations, the FAR Manual will become the sole source for information relating to the functions, assignments, responsibilities of DOE nuclear safety personnel. The FAR Manual identifies DOE directives that relate to nuclear safety and the specific DOE personnel who are responsible for implementing them. The manual includes only FARs that have been extracted from active directives that have been approved in accordance with the procedures contained in DOE Order 1321.1B.

Integrated assignment and path planning

Science.gov (United States)

Murphey, Robert A.

2005-11-01

A surge of interest in unmanned systems has exposed many new and challenging research problems across many fields of engineering and mathematics. These systems have the potential of transforming our society by replacing dangerous and dirty jobs with networks of moving machines. This vision is fundamentally separate from the modern view of robotics in that sophisticated behavior is realizable not by increasing individual vehicle complexity, but instead through collaborative teaming that relies on collective perception, abstraction, decision making, and manipulation. Obvious examples where collective robotics will make an impact include planetary exploration, space structure assembly, remote and undersea mining, hazardous material handling and clean-up, and search and rescue. Nonetheless, the phenomenon driving this technology trend is the increasing reliance of the US military on unmanned vehicles, specifically, aircraft. Only a few years ago, following years of resistance to the use of unmanned systems, the military and civilian leadership in the United States reversed itself and have recently demonstrated surprisingly broad acceptance of increasingly pervasive use of unmanned platforms in defense surveillance, and even attack. However, as rapidly as unmanned systems have gained acceptance, the defense research community has discovered the technical pitfalls that lie ahead, especially for operating collective groups of unmanned platforms. A great deal of talent and energy has been devoted to solving these technical problems, which tend to fall into two categories: resource allocation of vehicles to objectives, and path planning of vehicle trajectories. An extensive amount of research has been conducted in each direction, yet, surprisingly, very little work has considered the integrated problem of assignment and path planning. This dissertation presents a framework for studying integrated assignment and path planning and then moves on to suggest an exact

Integrating the Liberal Arts and Chemistry: A Series of General Chemistry Assignments to Develop Science Literacy

Science.gov (United States)

Miller, Diane M.; Chengelis Czegan, Demetra A.

2016-01-01

This paper describes assignments that have been implemented in a General Chemistry I course to promote science literacy. This course was chosen in particular because it reaches a broad audience, which includes nonscience majors. The assignment series begins with several discussions and tasks to develop information literacy, in which students find…

Transdisciplinary assignments in graduate health education as a model for future collaboration.

Science.gov (United States)

Christie, Catherine; Smith, A Russell; Bednarzyk, Michele

2007-01-01

Transdisciplinary health care continues to be at the forefront of patient treatment in the medical arena, in part due to escalating health care costs, an increasing aging population, and the development of multiple chronic diseases. Gaining the knowledge, experience, and principles associated with transdisciplinary teamwork to successfully prepare for modern-day practice is therefore essential for individuals of various health care professions. This report describes an assignment developed and implemented to facilitate professional interaction between graduate physical therapy, nutrition, and nursing students. The objectives of this assignment were to determine through student evaluation the effects of a transdisciplinary experience on students' understanding of the role of another discipline and students' communication skills across disciplines. When evaluating the assignment, students most often remarked that they developed a greater understanding of the roles of the included disciplines and reported a significant increase in communication skills. However, some students did not concur that this assignment was effective due to the scheduling conflicts and lack of teamwork that can occur during a collaborative project. The students' reports of their experiences in completing the assignment provide valuable insights for implementing and/or updating a preparatory transdisciplinary education component in other settings. Additional research can focus on the challenges faced by the majority of the students venturing into actual health care or "real-world" settings for comparative studies.

Association of the position of a hospital-acquired condition diagnosis code with changes in medicare severity diagnosis-related group assignment.

Science.gov (United States)

Johnson, Tricia; Kane, Jason M; Odwazny, Richard; McNutt, Robert

2014-11-01

Incentives to improve quality include paying less for adverse events, including the Centers for Medicare and Medicaid Services' policy to not pay additionally for events classified as hospital-acquired conditions (HACs). This policy is controversial, as variable coding practices at hospitals may lead to differences in the inclusion and position of HACs in the list of codes used for Medicare Severity Diagnosis-Related Group (MS-DRG) assignment. Evaluate changes in MS-DRG assignment for patients with an HAC and test the association of the position of an HAC in the list of International Classification of Diseases, 9th Revision (ICD-9) diagnosis codes with change in MS-DRG assignment. Retrospective analysis of patients discharged from hospital members of the University HealthSystem Consortium's Clinical Data Base between October 2007 and April 2008. Comparisons were made between the MS-DRG assigned when the HAC was not included in the list of ICD-9 diagnosis codes and the MS-DRG that would have been assigned had the HAC code been included in the assignment. Of the 7027 patients with an HAC, 13.8% changed MS-DRG assignment when the HAC was removed. An HAC in the second position versus third position or lower was associated with a 40-fold increase in the likelihood of MS-DRG change. The position of an HAC in the list of diagnosis codes, rather than the presence of an HAC, is associated with a change in MS-DRG assignment. HACs have little effect on reimbursement unless the HAC is in the second position and patients have minor severity of illness. © 2014 Society of Hospital Medicine.

GENERAL ISSUES CONCERNING THE ASSIGNMENT OF SOCIAL PARTS

Directory of Open Access Journals (Sweden)

Stela Mihăilescu

2012-11-01

Full Text Available By means of the present study, we try to offer a thorough image and an analysis concerning the assignment mode of social parts within a company having limited liability. The assignment of social parts is free and unrestricted except for the cases provided by article 202, paragraph 2 from Law no. 31/ 1990- the law of commercial companies with further modifications and completions and the ones provided in OUG no. 54/ 2010 concerning some measures for fighting fiscal evasion. By means of the assignment operation a transmission is made up by an assignment of social parts contract towards one or more already associated persons in the company or towards other individual or legal persons who are going to obtain the associate quality. The principle governing any assignment is the one of goods circulation freedom, a freedom restricted only by the public order and imperative judicial norms.

Stress Assignment in Reading Italian Polysyllabic Pseudowords

Science.gov (United States)

Sulpizio, Simone; Arduino, Lisa S.; Paizi, Despina; Burani, Cristina

2013-01-01

In 4 naming experiments we investigated how Italian readers assign stress to pseudowords. We assessed whether participants assign stress following distributional information such as stress neighborhood (the proportion and number of existent words sharing orthographic ending and stress pattern) and whether such distributional information affects…

Integer Linear Programming for Constrained Multi-Aspect Committee Review Assignment

Science.gov (United States)

Karimzadehgan, Maryam; Zhai, ChengXiang

2011-01-01

Automatic review assignment can significantly improve the productivity of many people such as conference organizers, journal editors and grant administrators. A general setup of the review assignment problem involves assigning a set of reviewers on a committee to a set of documents to be reviewed under the constraint of review quota so that the reviewers assigned to a document can collectively cover multiple topic aspects of the document. No previous work has addressed such a setup of committee review assignments while also considering matching multiple aspects of topics and expertise. In this paper, we tackle the problem of committee review assignment with multi-aspect expertise matching by casting it as an integer linear programming problem. The proposed algorithm can naturally accommodate any probabilistic or deterministic method for modeling multiple aspects to automate committee review assignments. Evaluation using a multi-aspect review assignment test set constructed using ACM SIGIR publications shows that the proposed algorithm is effective and efficient for committee review assignments based on multi-aspect expertise matching. PMID:22711970

Assignment and Correspondence Tracking System - Tactical / Operational Reporting

Data.gov (United States)

Social Security Administration — Reporting data store for the Assignment and Correspondence Tracking System (ACT). ACT automates the assignment and tracking of correspondence processing within the...

Statistical aspects of optimal treatment assignment

OpenAIRE

van der Linden, Willem J.

1980-01-01

The issues of treatment assignment is ordinarily dealt with within the framework of testing aptitude treatment interaction (ATI) hypothesis. ATI research mostly uses linear regression techniques, and an ATI exists when the aptitude treatment (AT) regression lines cross each other within the relevant interval of the aptitude variable. Consistent with this approach is the use of the points of interaction of AT regression lines as treatment-assignment rule. The replacement of such rules by monot...

7 CFR 1900.5 - Assignment of cases.

Science.gov (United States)

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Assignment of cases. 1900.5 Section 1900.5 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... REGULATIONS GENERAL Delegations of Authority § 1900.5 Assignment of cases. The State Director may, in writing...

METHOD FOR SOLVING FUZZY ASSIGNMENT PROBLEM USING MAGNITUDE RANKING TECHNIQUE

OpenAIRE

D. Selvi; R. Queen Mary; G. Velammal

2017-01-01

Assignment problems have various applications in the real world because of their wide applicability in industry, commerce, management science, etc. Traditional classical assignment problems cannot be successfully used for real life problem, hence the use of fuzzy assignment problems is more appropriate. In this paper, the fuzzy assignment problem is formulated to crisp assignment problem using Magnitude Ranking technique and Hungarian method has been applied to find an optimal solution. The N...

Automated grading of homework assignments and tests in introductory and intermediate statistics courses using active server pages.

Science.gov (United States)

Stockburger, D W

1999-05-01

Active server pages permit a software developer to customize the Web experience for users by inserting server-side script and database access into Web pages. This paper describes applications of these techniques and provides a primer on the use of these methods. Applications include a system that generates and grades individualized homework assignments and tests for statistics students. The student accesses the system as a Web page, prints out the assignment, does the assignment, and enters the answers on the Web page. The server, running on NT Server 4.0, grades the assignment, updates the grade book (on a database), and returns the answer key to the student.

A probabilistic approach for validating protein NMR chemical shift assignments

International Nuclear Information System (INIS)

Wang Bowei; Wang, Yunjun; Wishart, David S.

2010-01-01

It has been estimated that more than 20% of the proteins in the BMRB are improperly referenced and that about 1% of all chemical shift assignments are mis-assigned. These statistics also reflect the likelihood that any newly assigned protein will have shift assignment or shift referencing errors. The relatively high frequency of these errors continues to be a concern for the biomolecular NMR community. While several programs do exist to detect and/or correct chemical shift mis-referencing or chemical shift mis-assignments, most can only do one, or the other. The one program (SHIFTCOR) that is capable of handling both chemical shift mis-referencing and mis-assignments, requires the 3D structure coordinates of the target protein. Given that chemical shift mis-assignments and chemical shift re-referencing issues should ideally be addressed prior to 3D structure determination, there is a clear need to develop a structure-independent approach. Here, we present a new structure-independent protocol, which is based on using residue-specific and secondary structure-specific chemical shift distributions calculated over small (3-6 residue) fragments to identify mis-assigned resonances. The method is also able to identify and re-reference mis-referenced chemical shift assignments. Comparisons against existing re-referencing or mis-assignment detection programs show that the method is as good or superior to existing approaches. The protocol described here has been implemented into a freely available Java program called 'Probabilistic Approach for protein Nmr Assignment Validation (PANAV)' and as a web server (http://redpoll.pharmacy.ualberta.ca/PANAVhttp://redpoll.pharmacy.ualberta.ca/PANAV) which can be used to validate and/or correct as well as re-reference assigned protein chemical shifts.

APSY-NMR for protein backbone assignment in high-throughput structural biology

Energy Technology Data Exchange (ETDEWEB)

Dutta, Samit Kumar; Serrano, Pedro; Proudfoot, Andrew; Geralt, Michael [The Scripps Research Institute, Department of Integrative Structural and Computational Biology (United States); Pedrini, Bill [Paul Scherrer Institute (PSI), SwissFEL Project (Switzerland); Herrmann, Torsten [Université de Lyon, Institut des Sciences Analytiques, Centre de RMN à Très Hauts Champs, UMR 5280 CNRS, ENS Lyon, UCB Lyon 1 (France); Wüthrich, Kurt, E-mail: wuthrich@scripps.edu [The Scripps Research Institute, Department of Integrative Structural and Computational Biology (United States)

2015-01-15

A standard set of three APSY-NMR experiments has been used in daily practice to obtain polypeptide backbone NMR assignments in globular proteins with sizes up to about 150 residues, which had been identified as targets for structure determination by the Joint Center for Structural Genomics (JCSG) under the auspices of the Protein Structure Initiative (PSI). In a representative sample of 30 proteins, initial fully automated data analysis with the software UNIO-MATCH-2014 yielded complete or partial assignments for over 90 % of the residues. For most proteins the APSY data acquisition was completed in less than 30 h. The results of the automated procedure provided a basis for efficient interactive validation and extension to near-completion of the assignments by reference to the same 3D heteronuclear-resolved [{sup 1}H,{sup 1}H]-NOESY spectra that were subsequently used for the collection of conformational constraints. High-quality structures were obtained for all 30 proteins, using the J-UNIO protocol, which includes extensive automation of NMR structure determination.

Testing the Effectiveness of Online Assignments in Theory of Finance

Science.gov (United States)

Batu, Michael; Bower, Nancy; Lun, Esmond; Sadanand, Asha

2018-01-01

The authors investigated the effectiveness of online versus paper assignments using final examination scores in three cohorts of theory of finance. In particular, two cohorts were exposed to online assignments while another cohort was exposed to traditional assignments. The central result is that exposure to online assignments robustly leads to…

12 CFR 563e.28 - Assigned ratings.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Assigned ratings. 563e.28 Section 563e.28 Banks... for Assessing Performance § 563e.28 Assigned ratings. (a) Ratings in general. Subject to paragraphs (b... performance under the lending, investment and service tests, the community development test, the small savings...

Mapping Learning Outcomes and Assignment Tasks for SPIDER Activities

Directory of Open Access Journals (Sweden)

Lyn Brodie

2011-05-01

Full Text Available Modern engineering programs have to address rapidly changing technical content and have to enable students to develop transferable skills such as critical evaluation, communication skills and lifelong learning. This paper introduces a combined learning and assessment activity that provides students with opportunities to develop and practice their soft skills, but also extends their theoretical knowledge base. Key tasks included self directed inquiry, oral and written communication as well as peer assessment. To facilitate the SPIDER activities (Select, Prepare and Investigate, Discuss, Evaluate, Reflect, a software tool has been implemented in the learning management system Moodle. Evidence shows increased student engagement and better learning outcomes for both transferable as well as technical skills. The study focuses on generalising the relationship between learning outcomes and assignment tasks as well as activities that drive these tasks. Trail results inform the approach. Staff evaluations and their views of assignments and intended learning outcomes also supported this analysis.

Investigating Students' Use and Adoption of "With-Video Assignments": Lessons Learnt for Video-Based Open Educational Resources

Science.gov (United States)

Pappas, Ilias O.; Giannakos, Michail N.; Mikalef, Patrick

2017-01-01

The use of video-based open educational resources is widespread, and includes multiple approaches to implementation. In this paper, the term "with-video assignments" is introduced to portray video learning resources enhanced with assignments. The goal of this study is to examine the factors that influence students' intention to adopt…

Privacy-Preserving Task Assignment in Spatial Crowdsourcing

KAUST Repository

Liu, An

2017-09-20

With the progress of mobile devices and wireless networks, spatial crowdsourcing (SC) is emerging as a promising approach for problem solving. In SC, spatial tasks are assigned to and performed by a set of human workers. To enable effective task assignment, however, both workers and task requesters are required to disclose their locations to untrusted SC systems. In this paper, we study the problem of assigning workers to tasks in a way that location privacy for both workers and task requesters is preserved. We first combine the Paillier cryptosystem with Yao’s garbled circuits to construct a secure protocol that assigns the nearest worker to a task. Considering that this protocol cannot scale to a large number of workers, we then make use of Geohash, a hierarchical spatial index to design a more efficient protocol that can securely find approximate nearest workers. We theoretically show that these two protocols are secure against semi-honest adversaries. Through extensive experiments on two real-world datasets, we demonstrate the efficiency and effectiveness of our protocols.

On the Solution of the Eigenvalue Assignment Problem for Discrete-Time Systems

Directory of Open Access Journals (Sweden)

El-Sayed M. E. Mostafa

2017-01-01

Full Text Available The output feedback eigenvalue assignment problem for discrete-time systems is considered. The problem is formulated first as an unconstrained minimization problem, where a three-term nonlinear conjugate gradient method is proposed to find a local solution. In addition, a cut to the objective function is included, yielding an inequality constrained minimization problem, where a logarithmic barrier method is proposed for finding the local solution. The conjugate gradient method is further extended to tackle the eigenvalue assignment problem for the two cases of decentralized control systems and control systems with time delay. The performance of the methods is illustrated through various test examples.

Parental knowledge of child development and the assignment of tractor work to children.

Science.gov (United States)

Pickett, William; Marlenga, Barbara; Berg, Richard L

2003-07-01

Many childhood farm tractor injuries occur during the performance of work that was assigned by parents, and some tractor work is beyond the developmental capabilities of children. This has been highlighted recently by a policy statement authored by the American Academy of Pediatrics. The objective of this study was 1) to assess child development knowledge of farm parents who received a new resource, the North American Guidelines for Children's Agricultural Tasks (NAGCAT), and 2) to determine whether this knowledge was associated with use of NAGCAT in the assignment of tractor jobs and with compliance with 2 aspects of the NAGCAT tractor guideline. Secondary analysis of data collected during a randomized controlled trial that involved 450 farms in the United States and Canada was conducted. Variables assessed included 1) parental knowledge of child development across several age groups and 3 domains of child development (physical, cognitive, and psychosocial), 2) documentation of the most common tractor jobs assigned to each child, and 3) a report of whether NAGCAT was used in assigning these tractor jobs. High parental knowledge of child development was associated with enhanced use of NAGCAT and fewer violations when assigning tractor work to children. However, even in the presence of high knowledge, some farm parents still assigned to their children work that was in violation of NAGCAT. Educational interventions by themselves are not sufficient to remove many farm children from known occupational hazards. These findings are discussed in light of the recent policy statement on agricultural injuries from the American Academy of Pediatrics.

Dual earners’ willingness to accept an international assignment.

NARCIS (Netherlands)

van der Velde, E.G.; Bossink, C.J.H.; Jansen, P.G.W.

2005-01-01

Multinational organisations experience difficulties in finding managers willing to accept international assignments. This study has therefore focused on factors that can predict males' and females' willingness to accept international assignments, or to follow their partners on international

Task assignment and coaching

NARCIS (Netherlands)

Dominguez-Martinez, S.

2009-01-01

An important task of a manager is to motivate her subordinates. One way in which a manager can give incentives to junior employees is through the assignment of tasks. How a manager allocates tasks in an organization, provides information to the junior employees about his ability. Without coaching

Automated sequence- and stereo-specific assignment of methyl-labeled proteins by paramagnetic relaxation and methyl–methyl nuclear overhauser enhancement spectroscopy

International Nuclear Information System (INIS)

Venditti, Vincenzo; Fawzi, Nicolas L.; Clore, G. Marius

2011-01-01

Methyl-transverse relaxation optimized spectroscopy is rapidly becoming the preferred NMR technique for probing structure and dynamics of very large proteins up to ∼1 MDa in molecular size. Data interpretation, however, necessitates assignment of methyl groups which still presents a very challenging and time-consuming process. Here we demonstrate that, in combination with a known 3D structure, paramagnetic relaxation enhancement (PRE), induced by nitroxide spin-labels incorporated at only a few surface-exposed engineered cysteines, provides fast, straightforward and robust access to methyl group resonance assignments, including stereoassignments for the methyl groups of leucine and valine. Neither prior assignments, including backbone assignments, for the protein, nor experiments that transfer magnetization between methyl groups and the protein backbone, are required. PRE-derived assignments are refined by 4D methyl–methyl nuclear Overhauser enhancement data, eliminating ambiguities and errors that may arise due to the high sensitivity of PREs to the potential presence of sparsely-populated transient states.

Automated sequence- and stereo-specific assignment of methyl-labeled proteins by paramagnetic relaxation and methyl-methyl nuclear overhauser enhancement spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Venditti, Vincenzo; Fawzi, Nicolas L.; Clore, G. Marius, E-mail: mariusc@mail.nih.gov [National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Laboratory of Chemical Physics (United States)

2011-11-15

Methyl-transverse relaxation optimized spectroscopy is rapidly becoming the preferred NMR technique for probing structure and dynamics of very large proteins up to {approx}1 MDa in molecular size. Data interpretation, however, necessitates assignment of methyl groups which still presents a very challenging and time-consuming process. Here we demonstrate that, in combination with a known 3D structure, paramagnetic relaxation enhancement (PRE), induced by nitroxide spin-labels incorporated at only a few surface-exposed engineered cysteines, provides fast, straightforward and robust access to methyl group resonance assignments, including stereoassignments for the methyl groups of leucine and valine. Neither prior assignments, including backbone assignments, for the protein, nor experiments that transfer magnetization between methyl groups and the protein backbone, are required. PRE-derived assignments are refined by 4D methyl-methyl nuclear Overhauser enhancement data, eliminating ambiguities and errors that may arise due to the high sensitivity of PREs to the potential presence of sparsely-populated transient states.

[Preparation and assignment of medical reports: basis for settlement of compensation claims].

Science.gov (United States)

Thomann, K D

2011-03-01

Medical reporting represents an essential element in the settlement of personal claims. Moreover, the report prepares the basis for determing the compensation which is appropriate to the injury. The practice of instructing the expert medical assessor to obtain the medical documents required has proved a failure and causes delays in completion of the report. The doctor who is the expert medical assessor is often unsuccessful in obtaining these vital documents. In doubtful cases the expert will deliver his report without access to the vital documents. Incomplete reports affect the settlement adversely and promote unnecessary legal disputes. Many errors can be avoided if the officials of the relevant insurance company prepare the report assignment carefully. Such preparation includes clarification of the accident circumstances, requests for copies of the primary diagnosis and requests for hospital and medical reports, including full details of surgery carried out. Printouts of the daily reports by the doctors involved are also required. Of course these doctors must be released from the obligation to treat medical records confidentially. Furthermore, if the original documents are used, results of the injury which may seem insignificant will not be overlooked. The report assignment and primary medical documents should be sent to the medical assessor at the same time. The report assignment contains a detailed questionnaire which takes into account the particular aspects of the individual claim.

Likelihood of being seen within emergency departments’ assigned urgency times for poisoned and injured individuals

Directory of Open Access Journals (Sweden)

Rachel L. Rosenthal

2014-10-01

Full Text Available The objective of the present study is to determine the likelihood of injured or poisoned patients in special populations, such as those patients that are elderly and self-injurious, being seen within an emergency department’s triage nurse assigned urgency. Data from the National Hospital Ambulatory Medical Care Survey (2007 was utilized in this study. Multi-level models and multivariate linear regression models were used; patient age, sex, reported pain levels, wait time, and injury type were examined as potential predictors of being seen within assigned urgency. From a random sample across all US Emergency Departments, 5616 patients nested in 312 hospital emergency departments were included into the study. Typically, approximately 1 in 5 emergency department patients were not seen within their triage nurse assigned urgencies. The typical patient in the average hospital had an 81% likelihood of being seen within their assigned urgency. P atients who were oldest [odds ratio (OR=0.0990] and had self-inflicted injuries (vs assault OR=1.246 and OR=1.596 had the least likelihood to be seen within their assigned urgencies. As actual wait-time increased for patients, they were less likely to be seen within their assigned urgencies. The most powerful predictors of the study’s outcome were injury type and age, indicating that patients from special populations such as the elderly or those with injuries resulting from deliberate self-harm are less likely to be actually priority patients independent of triage nurse assigned urgencies.

Assessment of Random Assignment in Training and Test Sets using Generalized Cluster Analysis Technique

Directory of Open Access Journals (Sweden)

Sorana D. BOLBOACĂ

2011-06-01

Full Text Available Aim: The properness of random assignment of compounds in training and validation sets was assessed using the generalized cluster technique. Material and Method: A quantitative Structure-Activity Relationship model using Molecular Descriptors Family on Vertices was evaluated in terms of assignment of carboquinone derivatives in training and test sets during the leave-many-out analysis. Assignment of compounds was investigated using five variables: observed anticancer activity and four structure descriptors. Generalized cluster analysis with K-means algorithm was applied in order to investigate if the assignment of compounds was or not proper. The Euclidian distance and maximization of the initial distance using a cross-validation with a v-fold of 10 was applied. Results: All five variables included in analysis proved to have statistically significant contribution in identification of clusters. Three clusters were identified, each of them containing both carboquinone derivatives belonging to training as well as to test sets. The observed activity of carboquinone derivatives proved to be normal distributed on every. The presence of training and test sets in all clusters identified using generalized cluster analysis with K-means algorithm and the distribution of observed activity within clusters sustain a proper assignment of compounds in training and test set. Conclusion: Generalized cluster analysis using the K-means algorithm proved to be a valid method in assessment of random assignment of carboquinone derivatives in training and test sets.

Calibrated peer review assignments for the earth sciences

Science.gov (United States)

Rudd, J.A.; Wang, V.Z.; Cervato, C.; Ridky, R.W.

2009-01-01

Calibrated Peer Review ??? (CPR), a web-based instructional tool developed as part of the National Science Foundation reform initiatives in undergraduate science education, allows instructors to incorporate multiple writing assignments in large courses without overwhelming the instructor. This study reports successful implementation of CPR in a large, introductory geology course and student learning of geoscience content. For each CPR assignment in this study, students studied web-based and paper resources, wrote an essay, and reviewed seven essays (three from the instructor, three from peers, and their own) on the topic. Although many students expressed negative attitudes and concerns, particularly about the peer review process of this innovative instructional approach, they also recognized the learning potential of completing CPR assignments. Comparing instruction on earthquakes and plate boundaries using a CPR assignment vs. an instructional video lecture and homework essay with extensive instructor feedback, students mastered more content via CPR instruction.

Subcarrier Group Assignment for MC-CDMA Wireless Networks

Directory of Open Access Journals (Sweden)

Le-Ngoc Tho

2007-01-01

Full Text Available Two interference-based subcarrier group assignment strategies in dynamic resource allocation are proposed for MC-CDMA wireless systems to achieve high throughput in a multicell environment. Least interfered group assignment (LIGA selects for each session the subcarrier group on which the user receives the minimum interference, while best channel ratio group assignment (BCRGA chooses the subcarrier group with the largest channel response-to-interference ratio. Both analytical framework and simulation model are developed for evaluation of throughput distribution of the proposed schemes. An iterative approach is devised to handle the complex interdependency between multicell interference profiles in the throughput analysis. Illustrative results show significant throughput improvement offered by the interference-based assignment schemes for MC-CDMA multicell wireless systems. In particular, under low loading conditions, LIGA renders the best performance. However, as the load increases BCRGA tends to offer superior performance.

Subcarrier Group Assignment for MC-CDMA Wireless Networks

Directory of Open Access Journals (Sweden)

Tho Le-Ngoc

2007-12-01

Full Text Available Two interference-based subcarrier group assignment strategies in dynamic resource allocation are proposed for MC-CDMA wireless systems to achieve high throughput in a multicell environment. Least interfered group assignment (LIGA selects for each session the subcarrier group on which the user receives the minimum interference, while best channel ratio group assignment (BCRGA chooses the subcarrier group with the largest channel response-to-interference ratio. Both analytical framework and simulation model are developed for evaluation of throughput distribution of the proposed schemes. An iterative approach is devised to handle the complex interdependency between multicell interference profiles in the throughput analysis. Illustrative results show significant throughput improvement offered by the interference-based assignment schemes for MC-CDMA multicell wireless systems. In particular, under low loading conditions, LIGA renders the best performance. However, as the load increases BCRGA tends to offer superior performance.

Interactive visual exploration and refinement of cluster assignments.

Science.gov (United States)

Kern, Michael; Lex, Alexander; Gehlenborg, Nils; Johnson, Chris R

2017-09-12

With ever-increasing amounts of data produced in biology research, scientists are in need of efficient data analysis methods. Cluster analysis, combined with visualization of the results, is one such method that can be used to make sense of large data volumes. At the same time, cluster analysis is known to be imperfect and depends on the choice of algorithms, parameters, and distance measures. Most clustering algorithms don't properly account for ambiguity in the source data, as records are often assigned to discrete clusters, even if an assignment is unclear. While there are metrics and visualization techniques that allow analysts to compare clusterings or to judge cluster quality, there is no comprehensive method that allows analysts to evaluate, compare, and refine cluster assignments based on the source data, derived scores, and contextual data. In this paper, we introduce a method that explicitly visualizes the quality of cluster assignments, allows comparisons of clustering results and enables analysts to manually curate and refine cluster assignments. Our methods are applicable to matrix data clustered with partitional, hierarchical, and fuzzy clustering algorithms. Furthermore, we enable analysts to explore clustering results in context of other data, for example, to observe whether a clustering of genomic data results in a meaningful differentiation in phenotypes. Our methods are integrated into Caleydo StratomeX, a popular, web-based, disease subtype analysis tool. We show in a usage scenario that our approach can reveal ambiguities in cluster assignments and produce improved clusterings that better differentiate genotypes and phenotypes.

Generalized characteristic ratios assignment for commensurate fractional order systems with one zero.

Science.gov (United States)

Tabatabaei, Mohammad

2017-07-01

In this paper, a new method for determination of the desired characteristic equation and zero location of commensurate fractional order systems is presented. The concept of the characteristic ratio is extended for zero-including commensurate fractional order systems. The generalized version of characteristic ratios is defined such that the time-scaling property of characteristic ratios is also preserved. The monotonicity of the magnitude frequency response is employed to assign the generalized characteristic ratios for commensurate fractional order transfer functions with one zero. A simple pattern for characteristic ratios is proposed to reach a non-overshooting step response. Then, the proposed pattern is revisited to reach a low overshoot (say for example 2%) step response. Finally, zero-including controllers such as fractional order PI or lag (lead) controllers are designed using generalized characteristic ratios assignment method. Numerical simulations are provided to show the efficiency of the so designed controllers. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Student generated assignments about electrical circuits in a computer simulation

NARCIS (Netherlands)

Vreman-de Olde, Cornelise; de Jong, Anthonius J.M.

2004-01-01

In this study we investigated the design of assignments by students as a knowledge-generating activity. Students were required to design assignments for 'other students' in a computer simulation environment about electrical circuits. Assignments consisted of a question, alternatives, and feedback on

Readability of patient education materials in ophthalmology: a single-institution study and systematic review.

Science.gov (United States)

Williams, Andrew M; Muir, Kelly W; Rosdahl, Jullia A

2016-08-03

Patient education materials should be written at a level that is understandable for patients with low health literacy. The aims of this study are (1) to review the literature on readability of ophthalmic patient education materials and (2) to evaluate and revise our institution's patient education materials about glaucoma using evidence-based guidelines on writing for patients with low health literacy. A systematic search was conducted on the PubMed/MEDLINE database for studies that have evaluated readability level of ophthalmic patient education materials, and the reported readability scores were assessed. Additionally, we collected evidence-based guidelines for writing easy-to-read patient education materials, and these recommendations were applied to revise 12 patient education handouts on various glaucoma topics at our institution. Readability measures, including Flesch-Kincaid Grade Level (FKGL), and word count were calculated for the original and revised documents. The original and revised versions of the handouts were then scored in random order by two glaucoma specialists using the Suitability Assessment of Materials (SAM) instrument, a grading scale used to evaluate suitability of health information materials for patients. Paired t test was used to analyze changes in readability measures, word count, and SAM score between original and revised handouts. Finally, five glaucoma patients were interviewed to discuss the revised materials, and patient feedback was analyzed qualitatively. Our literature search included 13 studies that evaluated a total of 950 educational materials. Among the mean FKGL readability scores reported in these studies, the median was 11 (representing an eleventh-grade reading level). At our institution, handouts' readability averaged a tenth-grade reading level (FKGL = 10.0 ± 1.6), but revising the handouts improved their readability to a sixth-grade reading level (FKGL = 6.4 ± 1.2) (p readability and suitability of

On pole structure assignment in linear systems

Czech Academy of Sciences Publication Activity Database

Loiseau, J.-J.; Zagalak, Petr

2009-01-01

Roč. 82, č. 7 (2009), s. 1179-1192 ISSN 0020-7179 R&D Projects: GA ČR(CZ) GA102/07/1596 Institutional research plan: CEZ:AV0Z10750506 Keywords : linear systems * linear state feedback * pole structure assignment Subject RIV: BC - Control Systems Theory Impact factor: 1.124, year: 2009 http://library.utia.cas.cz/separaty/2009/AS/zagalak-on pole structure assignment in linear systems.pdf

Database proton NMR chemical shifts for RNA signal assignment and validation

Energy Technology Data Exchange (ETDEWEB)

Barton, Shawn; Heng Xiao [University of Maryland, Baltimore County, Howard Hughes Medical Institute (United States); Johnson, Bruce A., E-mail: bruce@onemoonscientific.com [University of Maryland, Baltimore County, Department of Chemistry and Biochemistry (United States); Summers, Michael F., E-mail: summers@hhmi.umbc.edu [University of Maryland, Baltimore County, Howard Hughes Medical Institute (United States)

2013-01-15

The Biological Magnetic Resonance Data Bank contains NMR chemical shift depositions for 132 RNAs and RNA-containing complexes. We have analyzed the {sup 1}H NMR chemical shifts reported for non-exchangeable protons of residues that reside within A-form helical regions of these RNAs. The analysis focused on the central base pair within a stretch of three adjacent base pairs (BP triplets), and included both Watson-Crick (WC; G:C, A:U) and G:U wobble pairs. Chemical shift values were included for all 4{sup 3} possible WC-BP triplets, as well as 137 additional triplets that contain one or more G:U wobbles. Sequence-dependent chemical shift correlations were identified, including correlations involving terminating base pairs within the triplets and canonical and non-canonical structures adjacent to the BP triplets (i.e. bulges, loops, WC and non-WC BPs), despite the fact that the NMR data were obtained under different conditions of pH, buffer, ionic strength, and temperature. A computer program (RNAShifts) was developed that enables convenient comparison of RNA {sup 1}H NMR assignments with database predictions, which should facilitate future signal assignment/validation efforts and enable rapid identification of non-canonical RNA structures and RNA-ligand/protein interaction sites.

Personnel shift assignment: Existence conditions and network models

NARCIS (Netherlands)

van den Berg, Jeroen P.; van den Berg, J.P.; Panton, David M.

1994-01-01

The personnel scheduling problem is known to be a five-stage process in which the final stage involves the assignment of shifts to the days worked in the schedule. This paper discusses the existence conditions for both continuous and forward rotating shift assignments and heuristic network

75 FR 55355 - Delegation of Authority and Assignment of Responsibility

Science.gov (United States)

2010-09-10

... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authority and Assignment of Responsibility Secretary's Order 4-2010 Subject: Delegation of Authority and Assignment of Responsibility to the... delegations and assignments in full force and effect, except as expressly modified herein. 4. Delegation of...

Staff assignment practices in nursing homes: review of the literature.

Science.gov (United States)

Rahman, Anna; Straker, Jane K; Manning, Lydia

2009-01-01

Consistent assignment, whereby nursing home staff members, particularly certified nurse aides, are assigned to the same residents on most shifts, is increasingly viewed as a cornerstone of culture change in nursing homes. It has been advocated as a best-care model that increases residents' quality of life while contributing to a more stable frontline staff. Given these potential benefits, consistent assignment is now widely viewed as superior to rotating assignment, an alternative staffing model that aims to distribute care burden more fairly among staff and ensure that workers are familiar with most residents. Despite favorable anecdotal reports about the benefits of consistent assignment, the research literature reports mixed and sometimes contradictory findings for this staffing practice. This article reviews the research pertaining to staff assignment practices in nursing homes. Reviewed here are 13 reports on experimental trials (6 reports), evaluation research (4 reports), and nursing home surveys (3 reports). The review reveals broad diversity in staffing practices and raises questions that challenge popular assumptions about consistent assignment. The article closes with a discussion of the research, policy, and practice implications of the research findings.

75 FR 55354 - Delegation of Authority and Assignment of Responsibilities

Science.gov (United States)

2010-09-10

... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authority and Assignment of Responsibilities Secretary's Order 3-2010 Subject: Delegation of Authority and Assignment of Responsibilities to... Secretary to enforce sections 18A and 18B of the FLSA. 4. Delegation of Authority and Assignment of...

Minutes of the 28th Annual Plutonium Sample Exchange Meeting. Part II: metal sample exchange

International Nuclear Information System (INIS)

1984-01-01

Contents of this publication include the following list of participating laboratories; agenda; attendees; minutes of October 25 and 26 meeting; and handout materials supplied by speakers. The handout materials cover the following: statistics and reporting; plutonium - chemical assay 100% minus impurities; americium neptunium, uranium, carbon and iron data; emission spectroscopy data; plutonium metal sample exchange; the calorimetry sample exchange; chlorine determination in plutonium metal using phyrohydrolysis; spectrophotometric determination of 238-plutonium in oxide; plutonium measurement capabilities at the Savannah River Plant; and robotics in radiochemical laboratory

Quality Control Test for Sequence-Phenotype Assignments

Science.gov (United States)

Ortiz, Maria Teresa Lara; Rosario, Pablo Benjamín Leon; Luna-Nevarez, Pablo; Gamez, Alba Savin; Martínez-del Campo, Ana; Del Rio, Gabriel

2015-01-01

Relating a gene mutation to a phenotype is a common task in different disciplines such as protein biochemistry. In this endeavour, it is common to find false relationships arising from mutations introduced by cells that may be depurated using a phenotypic assay; yet, such phenotypic assays may introduce additional false relationships arising from experimental errors. Here we introduce the use of high-throughput DNA sequencers and statistical analysis aimed to identify incorrect DNA sequence-phenotype assignments and observed that 10–20% of these false assignments are expected in large screenings aimed to identify critical residues for protein function. We further show that this level of incorrect DNA sequence-phenotype assignments may significantly alter our understanding about the structure-function relationship of proteins. We have made available an implementation of our method at http://bis.ifc.unam.mx/en/software/chispas. PMID:25700273

25 CFR 225.33 - Assignment of minerals agreements.

Science.gov (United States)

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements. An...

Automating Formative and Summative Feedback for Individualised Assignments

Science.gov (United States)

Hamilton, Ian Robert

2009-01-01

Purpose: The purpose of this paper is to report on the rationale behind the use of a unique paper-based individualised accounting assignment, which automated the provision to students of immediate formative and timely summative feedback. Design/methodology/approach: As students worked towards completing their assignment, the package provided…

submission of art studio-based assignments: students experience

African Journals Online (AJOL)

PUBLICATIONS1

are reluctant to complete their studio assignments on time are critically ... tative and qualitative data, derived from survey and interviews were used to ... is therefore exploratory and studio based. It ... mogenous group of students who report pro- ... Assignment management .... The analyses in this study are based on data.

Heuristic for Task-Worker Assignment with Varying Learning Slopes

Directory of Open Access Journals (Sweden)

Wipawee Tharmmaphornphilas

2010-04-01

Full Text Available Fashion industry has variety products, so the multi-skilled workers are required to improve flexibility in production and assignment. Generally the supervisor will assign task to the workers based on skill and skill levels of worker. Since in fashion industry new product styles are launched more frequently and the order size tends to be smaller, the workers always learn when the raw material and the production process changes. Consequently they require less time to produce the succeeding units of a task based on their learning ability. Since the workers have both experience and inexperience workers, so each worker has different skill level and learning ability. Consequently, the assignment which assumed constant skill level is not proper to use. This paper proposes a task-worker assignment considering worker skill levels and learning abilities. Processing time of each worker changes along production period due to a worker learning ability. We focus on a task-worker assignment in a fashion industry where tasks are ordered in series; the number of tasks is greater than the number of workers. Therefore, workers can perform multiple assignments followed the precedence restriction as an assembly line balancing problem. The problem is formulated in an integer linear programming model with objective to minimize makespan. A heuristic is proposed to determine the lower bound (LB and the upper bound (UB of the problem and the best assignment is determined. The performance of the heuristic method is tested by comparing quality of solution and computational time to optimal solutions.

Dynamic online peer evaluations to improve group assignments in nursing e-learning environment.

Science.gov (United States)

Adwan, Jehad

2016-06-01

The purpose of this research was to evaluate the use of online peer evaluation forms for online group activities in improving group project outcomes. The investigator developed and used a web-based Google Forms® self and peer evaluation form of 2 group assignments' rubric for junior and senior nursing students. The form covered elements of the assignments including: research activity, analysis of the literature, writing of report, participation in making of presentation, overall contribution to the project, and participation in the weekly group discussions. Items were rated from 1 (did not contribute) to 5 (outstanding contribution) in addition to NA when one activity did not apply. The self and peer evaluation process was conducted twice: once after group assignment 1 and once after group assignment 2. The group assignments final products were done in the form of VoiceThread online presentations that were shared with the rest of the class reflecting the groups' work on a health informatics topic of interest. Data collected as the students completed self and peer evaluations for group assignments 1 and 2. Also, optional comments regarding member performance were collected to add contextual information in addition to ratings. Students received credit for completing the peer evaluations and the grade for the particular assignment was affected by their performance based on peer evaluations of their contributions. Students' peer evaluations showed in a color-coded spreadsheet which enabled the course faculty to view real time results of students' ratings after each assignment. The faculty provided timely and tailored feedback to groups or individuals as needed, using positive feedback and commending high performance while urging struggling individual students and groups to improve lower ratings in specific areas. Comparing evaluations of both assignments, there were statistically significant improvements among all students. The mean scores of the entire sample were

Assignment Procedures in the Air Force Procurement Management Information System.

Science.gov (United States)

Ward, Joe H., Jr.; And Others

An overview is presented of the procedure for offering jobs in the Air Force Procurement Management Information System (PROMIS), an assignment system which makes possible the use of human resources research findings to improve individual personnel assignments. A general framework for viewing personnel assignment systems is presented; then job…

A property of assignment type mixed integer linear programming problems

NARCIS (Netherlands)

Benders, J.F.; van Nunen, J.A.E.E.

1982-01-01

In this paper we will proof that rather tight upper bounds can be given for the number of non-unique assignments that are achieved after solving the linear programming relaxation of some types of mixed integer linear assignment problems. Since in these cases the number of splitted assignments is

41 CFR 105-8.152 - Program accessibility: Assignment of space.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Program accessibility: Assignment of space. 105-8.152 Section 105-8.152 Public Contracts and Property Management Federal Property...-8.152 Program accessibility: Assignment of space. (a) When GSA assigns or reassigns space to an...

Scaffolding Assignments and Activities for Undergraduate Research Methods

Science.gov (United States)

Fisher, Sarah; Justwan, Florian

2018-01-01

This article details assignments and lessons created for and tested in research methods courses at two different universities, a large state school and a small liberal arts college. Each assignment or activity utilized scaffolding. Students were asked to push beyond their comfort zone while utilizing concrete and/or creative examples,…

The Presentation Assignment: Creating Learning Opportunities for Diverse Student Populations.

Science.gov (United States)

Spencer, Brenda H.; Bartle-Angus, Kathryn

2000-01-01

Finds the presentation assignment to be an effective method of providing students with the opportunity to apply the literacy skills they are learning in ways that are personally meaningful. Describes the presentation assignment framework and provides an example of an assignment that required students to analyze and interpret works of literature…

Triage level assignment and nurse characteristics and experience.

Science.gov (United States)

Gómez-Angelats, Elisenda; Miró, Òscar; Bragulat Baur, Ernesto; Antolín Santaliestra, Alberto; Sánchez Sánchez, Miquel

2018-06-01

To study the relation between nursing staff demographics and experience and their assignment of triage level in the emergency department. One-year retrospective observational study in the triage area of a tertiary care urban university hospital that applies the Andorran-Spanish triage model. Variables studied were age, gender, nursing experience, triage experience, shift, usual level of emergency work the nurse undertakes, number of triage decisions made, and percentage of patients assigned to each level. Fifty nurses (5 men, 45 women) with a mean (SD) age of 45 (9) years triaged 67 803 patients during the year. Nurses classified more patients in level 5 on the morning shift (7.9%) than on the afternoon shift (5.5%) (P=.003). The difference in the rate of level-5 triage classification became significant when nurses were older (β = 0.092, P=.037) and experience was greater (β = 0.103, P=.017). The number of triages recorded by a nurse was significantly and directly related to the percentage of patients assigned to level 3 (β = 0.003, P=.006) and inversely related to the percentages assigned to level 4 (β = -0.002, P=.008) and level 5 (β = -0.001, P=.017). We found that triage level assignments were related to age, experience, shift, and total number of patients triaged by a nurse.

Visual words assignment via information-theoretic manifold embedding.

Science.gov (United States)

Deng, Yue; Li, Yipeng; Qian, Yanjun; Ji, Xiangyang; Dai, Qionghai

2014-10-01

Codebook-based learning provides a flexible way to extract the contents of an image in a data-driven manner for visual recognition. One central task in such frameworks is codeword assignment, which allocates local image descriptors to the most similar codewords in the dictionary to generate histogram for categorization. Nevertheless, existing assignment approaches, e.g., nearest neighbors strategy (hard assignment) and Gaussian similarity (soft assignment), suffer from two problems: 1) too strong Euclidean assumption and 2) neglecting the label information of the local descriptors. To address the aforementioned two challenges, we propose a graph assignment method with maximal mutual information (GAMI) regularization. GAMI takes the power of manifold structure to better reveal the relationship of massive number of local features by nonlinear graph metric. Meanwhile, the mutual information of descriptor-label pairs is ultimately optimized in the embedding space for the sake of enhancing the discriminant property of the selected codewords. According to such objective, two optimization models, i.e., inexact-GAMI and exact-GAMI, are respectively proposed in this paper. The inexact model can be efficiently solved with a closed-from solution. The stricter exact-GAMI nonparametrically estimates the entropy of descriptor-label pairs in the embedding space and thus leads to a relatively complicated but still trackable optimization. The effectiveness of GAMI models are verified on both the public and our own datasets.

A Bio-Inspired Approach to Traffic Network Equilibrium Assignment Problem.

Science.gov (United States)

Zhang, Xiaoge; Mahadevan, Sankaran

2018-04-01

Finding an equilibrium state of the traffic assignment plays a significant role in the design of transportation networks. We adapt the path finding mathematical model of slime mold Physarum polycephalum to solve the traffic equilibrium assignment problem. We make three contributions in this paper. First, we propose a generalized Physarum model to solve the shortest path problem in directed and asymmetric graphs. Second, we extend it further to resolve the network design problem with multiple source nodes and sink nodes. At last, we demonstrate that the Physarum solver converges to the user-optimized (Wardrop) equilibrium by dynamically updating the costs of links in the network. In addition, convergence of the developed algorithm is proved. Numerical examples are used to demonstrate the efficiency of the proposed algorithm. The superiority of the proposed algorithm is demonstrated in comparison with several other algorithms, including the Frank-Wolfe algorithm, conjugate Frank-Wolfe algorithm, biconjugate Frank-Wolfe algorithm, and gradient projection algorithm.

Contact replacement for NMR resonance assignment.

Science.gov (United States)

Xiong, Fei; Pandurangan, Gopal; Bailey-Kellogg, Chris

2008-07-01

Complementing its traditional role in structural studies of proteins, nuclear magnetic resonance (NMR) spectroscopy is playing an increasingly important role in functional studies. NMR dynamics experiments characterize motions involved in target recognition, ligand binding, etc., while NMR chemical shift perturbation experiments identify and localize protein-protein and protein-ligand interactions. The key bottleneck in these studies is to determine the backbone resonance assignment, which allows spectral peaks to be mapped to specific atoms. This article develops a novel approach to address that bottleneck, exploiting an available X-ray structure or homology model to assign the entire backbone from a set of relatively fast and cheap NMR experiments. We formulate contact replacement for resonance assignment as the problem of computing correspondences between a contact graph representing the structure and an NMR graph representing the data; the NMR graph is a significantly corrupted, ambiguous version of the contact graph. We first show that by combining connectivity and amino acid type information, and exploiting the random structure of the noise, one can provably determine unique correspondences in polynomial time with high probability, even in the presence of significant noise (a constant number of noisy edges per vertex). We then detail an efficient randomized algorithm and show that, over a variety of experimental and synthetic datasets, it is robust to typical levels of structural variation (1-2 AA), noise (250-600%) and missings (10-40%). Our algorithm achieves very good overall assignment accuracy, above 80% in alpha-helices, 70% in beta-sheets and 60% in loop regions. Our contact replacement algorithm is implemented in platform-independent Python code. The software can be freely obtained for academic use by request from the authors.

28 CFR 545.23 - Inmate work/program assignment.

Science.gov (United States)

2010-07-01

... community living area, unless the pretrial inmate has signed a waiver of his or her right not to work (see... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Inmate work/program assignment. 545.23... WORK AND COMPENSATION Inmate Work and Performance Pay Program § 545.23 Inmate work/program assignment...

Optimal assignment of incoming flights to baggage carousels at airports

DEFF Research Database (Denmark)

Barth, Torben C.

The problem considered in this report is an assignment problem occurring at airports. This problem concerns the assignment of baggage carousels in baggage claim halls to arriving aircraft (baggage carousel assignment problem). This is a highly dynamic problem since disruptions frequently occur du...... and in general is a substantial support in decision making....

PARETO OPTIMAL SOLUTIONS FOR MULTI-OBJECTIVE GENERALIZED ASSIGNMENT PROBLEM

Directory of Open Access Journals (Sweden)

S. Prakash

2012-01-01

Full Text Available

ENGLISH ABSTRACT: The Multi-Objective Generalized Assignment Problem (MGAP with two objectives, where one objective is linear and the other one is non-linear, has been considered, with the constraints that a job is assigned to only one worker – though he may be assigned more than one job, depending upon the time available to him. An algorithm is proposed to find the set of Pareto optimal solutions of the problem, determining assignments of jobs to workers with two objectives without setting priorities for them. The two objectives are to minimise the total cost of the assignment and to reduce the time taken to complete all the jobs.

AFRIKAANSE OPSOMMING: ‘n Multi-doelwit veralgemeende toekenningsprobleem (“multi-objective generalised assignment problem – MGAP” met twee doelwitte, waar die een lineêr en die ander nielineêr is nie, word bestudeer, met die randvoorwaarde dat ‘n taak slegs toegedeel word aan een werker – alhoewel meer as een taak aan hom toegedeel kan word sou die tyd beskikbaar wees. ‘n Algoritme word voorgestel om die stel Pareto-optimale oplossings te vind wat die taaktoedelings aan werkers onderhewig aan die twee doelwitte doen sonder dat prioriteite toegeken word. Die twee doelwitte is om die totale koste van die opdrag te minimiseer en om die tyd te verminder om al die take te voltooi.

Game theory and traffic assignment.

Science.gov (United States)

2013-09-01

Traffic assignment is used to determine the number of users on roadway links in a network. While this problem has : been widely studied in transportation literature, its use of the concept of equilibrium has attracted considerable interest : in the f...

Sequential assignment of proline-rich regions in proteins: Application to modular binding domain complexes

International Nuclear Information System (INIS)

Kanelis, Voula; Donaldson, Logan; Muhandiram, D.R.; Rotin, Daniela; Forman-Kay, Julie D.; Kay, Lewis E.

2000-01-01

Many protein-protein interactions involve amino acid sequences containing proline-rich motifs and even poly-proline stretches. The lack of amide protons in such regions complicates assignment, since 1 HN-based triple-resonance assignment strategies cannot be employed. Two such systems that we are currently studying include an SH2 domain from the protein Crk with a region containing 9 prolines in a 14 amino acid sequence, as well as a WW domain that interacts with a proline-rich target. A modified version of the HACAN pulse scheme, originally described by Bax and co-workers [Wang et al. (1995) J. Biomol. NMR, 5, 376-382], and an experiment which correlates the intra-residue 1 H α , 13 C α / 13 C β chemical shifts with the 15 N shift of the subsequent residue are presented and applied to the two systems listed above, allowing sequential assignment of the molecules

Simulated annealing algorithm for solving chambering student-case assignment problem

Science.gov (United States)

Ghazali, Saadiah; Abdul-Rahman, Syariza

2015-12-01

The problem related to project assignment problem is one of popular practical problem that appear nowadays. The challenge of solving the problem raise whenever the complexity related to preferences, the existence of real-world constraints and problem size increased. This study focuses on solving a chambering student-case assignment problem by using a simulated annealing algorithm where this problem is classified under project assignment problem. The project assignment problem is considered as hard combinatorial optimization problem and solving it using a metaheuristic approach is an advantage because it could return a good solution in a reasonable time. The problem of assigning chambering students to cases has never been addressed in the literature before. For the proposed problem, it is essential for law graduates to peruse in chambers before they are qualified to become legal counselor. Thus, assigning the chambering students to cases is a critically needed especially when involving many preferences. Hence, this study presents a preliminary study of the proposed project assignment problem. The objective of the study is to minimize the total completion time for all students in solving the given cases. This study employed a minimum cost greedy heuristic in order to construct a feasible initial solution. The search then is preceded with a simulated annealing algorithm for further improvement of solution quality. The analysis of the obtained result has shown that the proposed simulated annealing algorithm has greatly improved the solution constructed by the minimum cost greedy heuristic. Hence, this research has demonstrated the advantages of solving project assignment problem by using metaheuristic techniques.

Efficient Mechanisms to Allocate Assignment Incentives in the Navy

National Research Council Canada - National Science Library

Nimon, R. W; Hall, Ricky D; Zaki, Hossam

2005-01-01

.... All assignments, however, may not necessarily be voluntary. These assignments (jobs) have been labeled as "hard to fill" by Navy leadership, and the Navy has implemented market-based, cash stipends to attract Sailors to these jobs...

Ant Colony Algorithm and Simulation for Robust Airport Gate Assignment

Directory of Open Access Journals (Sweden)

Hui Zhao

2014-01-01

Full Text Available Airport gate assignment is core task for airport ground operations. Due to the fact that the departure and arrival time of flights may be influenced by many random factors, the airport gate assignment scheme may encounter gate conflict and many other problems. This paper aims at finding a robust solution for airport gate assignment problem. A mixed integer model is proposed to formulate the problem, and colony algorithm is designed to solve this model. Simulation result shows that, in consideration of robustness, the ability of antidisturbance for airport gate assignment scheme has much improved.

Fast and accurate resonance assignment of small-to-large proteins by combining automated and manual approaches.

Science.gov (United States)

Niklasson, Markus; Ahlner, Alexandra; Andresen, Cecilia; Marsh, Joseph A; Lundström, Patrik

2015-01-01

The process of resonance assignment is fundamental to most NMR studies of protein structure and dynamics. Unfortunately, the manual assignment of residues is tedious and time-consuming, and can represent a significant bottleneck for further characterization. Furthermore, while automated approaches have been developed, they are often limited in their accuracy, particularly for larger proteins. Here, we address this by introducing the software COMPASS, which, by combining automated resonance assignment with manual intervention, is able to achieve accuracy approaching that from manual assignments at greatly accelerated speeds. Moreover, by including the option to compensate for isotope shift effects in deuterated proteins, COMPASS is far more accurate for larger proteins than existing automated methods. COMPASS is an open-source project licensed under GNU General Public License and is available for download from http://www.liu.se/forskning/foass/tidigare-foass/patrik-lundstrom/software?l=en. Source code and binaries for Linux, Mac OS X and Microsoft Windows are available.

Fast and accurate resonance assignment of small-to-large proteins by combining automated and manual approaches.

Directory of Open Access Journals (Sweden)

Markus Niklasson

2015-01-01

Full Text Available The process of resonance assignment is fundamental to most NMR studies of protein structure and dynamics. Unfortunately, the manual assignment of residues is tedious and time-consuming, and can represent a significant bottleneck for further characterization. Furthermore, while automated approaches have been developed, they are often limited in their accuracy, particularly for larger proteins. Here, we address this by introducing the software COMPASS, which, by combining automated resonance assignment with manual intervention, is able to achieve accuracy approaching that from manual assignments at greatly accelerated speeds. Moreover, by including the option to compensate for isotope shift effects in deuterated proteins, COMPASS is far more accurate for larger proteins than existing automated methods. COMPASS is an open-source project licensed under GNU General Public License and is available for download from http://www.liu.se/forskning/foass/tidigare-foass/patrik-lundstrom/software?l=en. Source code and binaries for Linux, Mac OS X and Microsoft Windows are available.

Preoperative patient education: can we improve satisfaction and reduce anxiety?

Directory of Open Access Journals (Sweden)

Jaime Ortiz

2015-02-01

Full Text Available BACKGROUND AND OBJECTIVES: Patients' knowledge deficits concerning anesthesia and the anesthesiologist's role in their care may contribute to anxiety. The objective of this study was to develop anesthesia patient education materials that would help improve patient's satisfaction regarding their knowledge of the perioperative process and decrease anxiety in a community hospital with a large Spanish-speaking population. METHODS: A survey (Survey A in English and Spanish was administered to all adult anesthesiology preoperative clinic patients during a 4-week period. The data were analyzed and then a patient education handout was developed in both English and Spanish to assist with our patients' major concerns. A second survey (Survey B was administered that was completed after the education handout had been put into use at the clinic. The survey asked for basic demographic information and included questions on satisfaction with regard to understanding of anesthesia as well as worries regarding surgery and pain. RESULTS: In the patients who received the handout, statistically significant improvement was found in the questions that asked about satisfaction with regard to understanding of type of anesthesia, options for pain control, what patients are supposed to do on the day of surgery, and the amount of information given with regard to anesthetic plan. There was no difference in anxiety related to surgery in patients who received the educational handout compared to those patients who did not. CONCLUSIONS: Patient education handouts improved patient's satisfaction regarding their knowledge of the perioperative process but did not reduce anxiety related to surgery.

Midwifery students' evaluation of team-based academic assignments involving peer-marking.

Science.gov (United States)

Parratt, Jenny A; Fahy, Kathleen M; Hastie, Carolyn R

2014-03-01

Midwives should be skilled team workers in maternity units and in group practices. Poor teamwork skills are a significant cause of adverse maternity care outcomes. Despite Australian and International regulatory requirements that all midwifery graduates are competent in teamwork, the systematic teaching and assessment of teamwork skills is lacking in higher education. How do midwifery students evaluate participation in team-based academic assignments, which include giving and receiving peer feedback? First and third year Bachelor of Midwifery students who volunteered (24 of 56 students). Participatory Action Research with data collection via anonymous online surveys. There was general agreement that team based assignments; (i) should have peer-marking, (ii) help clarify what is meant by teamwork, (iii) develop communication skills, (iv) promote student-to-student learning. Third year students strongly agreed that teams: (i) are valuable preparation for teamwork in practice, (ii) help meet Australian midwifery competency 8, and (iii) were enjoyable. The majority of third year students agreed with statements that their teams were effectively coordinated and team members shared responsibility for work equally; first year students strongly disagreed with these statements. Students' qualitative comments substantiated and expanded on these findings. The majority of students valued teacher feedback on well-developed drafts of the team's assignment prior to marking. Based on these findings we changed practice and created more clearly structured team-based assignments with specific marking criteria. We are developing supporting lessons to teach specific teamwork skills: together these resources are called "TeamUP". TeamUP should be implemented in all pre-registration Midwifery courses to foster students' teamwork skills and readiness for practice. Copyright © 2013 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

Assigning agents to a line

DEFF Research Database (Denmark)

Hougaard, Jens Leth; Moreno-Ternero, Juan D.; Østerdal, Lars Peter Raahave

2014-01-01

minimizing modification of the classic random priority method to solve this class of problems. We also provide some logical relations in our setting among standard axioms in the literature on assignment problems, and explore the robustness of our results to several extensions of our setting....

A Randomized Trial Comparing Mail versus In-Office Distribution of the CAHPS Clinician and Group Survey

Science.gov (United States)

Anastario, Michael P; Rodriguez, Hector P; Gallagher, Patricia M; Cleary, Paul D; Shaller, Dale; Rogers, William H; Bogen, Karen; Safran, Dana Gelb

2010-01-01

Objective To assess the effect of survey distribution protocol (mail versus handout) on data quality and measurement of patient care experiences. Data Sources/Study Setting Multisite randomized trial of survey distribution protocols. Analytic sample included 2,477 patients of 15 clinicians at three practice sites in New York State. Data Collection/Extraction Methods Mail and handout distribution modes were alternated weekly at each site for 6 weeks. Principal Findings Handout protocols yielded an incomplete distribution rate (74 percent) and lower overall response rates (40 percent versus 58 percent) compared with mail. Handout distribution rates decreased over time and resulted in more favorable survey scores compared with mailed surveys. There were significant mode–physician interaction effects, indicating that data cannot simply be pooled and adjusted for mode. Conclusions In-office survey distribution has the potential to bias measurement and comparison of physicians and sites on patient care experiences. Incomplete distribution rates observed in-office, together with between-office differences in distribution rates and declining rates over time suggest staff may be burdened by the process and selective in their choice of patients. Further testing with a larger physician and site sample is important to definitively establish the potential role for in-office distribution in obtaining reliable, valid assessment of patient care experiences. PMID:20579126

Covariance NMR Processing and Analysis for Protein Assignment.

Science.gov (United States)

Harden, Bradley J; Frueh, Dominique P

2018-01-01

During NMR resonance assignment it is often necessary to relate nuclei to one another indirectly, through their common correlations to other nuclei. Covariance NMR has emerged as a powerful technique to correlate such nuclei without relying on error-prone peak peaking. However, false-positive artifacts in covariance spectra have impeded a general application to proteins. We recently introduced pre- and postprocessing steps to reduce the prevalence of artifacts in covariance spectra, allowing for the calculation of a variety of 4D covariance maps obtained from diverse combinations of pairs of 3D spectra, and we have employed them to assign backbone and sidechain resonances in two large and challenging proteins. In this chapter, we present a detailed protocol describing how to (1) properly prepare existing 3D spectra for covariance, (2) understand and apply our processing script, and (3) navigate and interpret the resulting 4D spectra. We also provide solutions to a number of errors that may occur when using our script, and we offer practical advice when assigning difficult signals. We believe such 4D spectra, and covariance NMR in general, can play an integral role in the assignment of NMR signals.

Genetics of traffic assignment models for strategic transport planning

NARCIS (Netherlands)

Bliemer, M.C.J.; Raadsen, M.P.H.; Brederode, L.J.N.; Bell, M.G.H.; Wismans, Luc Johannes Josephus; Smith, M.J.

2016-01-01

This paper presents a review and classification of traffic assignment models for strategic transport planning purposes by using concepts analogous to genetics in biology. Traffic assignment models share the same theoretical framework (DNA), but differ in capability (genes). We argue that all traffic

Designing Internet research assignments: building a framework for instructor collaboration

Directory of Open Access Journals (Sweden)

David Ward

2000-01-01

Full Text Available Internet knowledge is increasing steadily among instructors in the academic world. As courses incorporate more instructional technology, traditional undergraduate research assignments are adapting to reflect the changing world of information and information access. New library assignments reflect this shift as well, with term papers and research projects asking students to use Web sites as an information resource, in addition to the standard literature of periodicals and monographs. But the many pitfalls the library profession has learned in its own metamorphosis during the past decade are often repeated in these newer course assignments. The authors in this paper present a framework for librarians to interact with instructors to incorporate Internet resources into traditional term paper and research assignments. They suggest a framework for creating sample assignments librarians can take to campus instructional units, to show the teaching community at large what the library profession has learned from first-hand experience.

Graphical analysis of NMR structural quality and interactive contact map of NOE assignments in ARIA

Directory of Open Access Journals (Sweden)

Malliavin Thérèse E

2008-06-01

Full Text Available Abstract Background The Ambiguous Restraints for Iterative Assignment (ARIA approach is widely used for NMR structure determination. It is based on simultaneously calculating structures and assigning NOE through an iterative protocol. The final solution consists of a set of conformers and a list of most probable assignments for the input NOE peak list. Results ARIA was extended with a series of graphical tools to facilitate a detailed analysis of the intermediate and final results of the ARIA protocol. These additional features provide (i an interactive contact map, serving as a tool for the analysis of assignments, and (ii graphical representations of structure quality scores and restraint statistics. The interactive contact map between residues can be clicked to obtain information about the restraints and their contributions. Profiles of quality scores are plotted along the protein sequence, and contact maps provide information of the agreement with the data on a residue pair level. Conclusion The graphical tools and outputs described here significantly extend the validation and analysis possibilities of NOE assignments given by ARIA as well as the analysis of the quality of the final structure ensemble. These tools are included in the latest version of ARIA, which is available at http://aria.pasteur.fr. The Web site also contains an installation guide, a user manual and example calculations.

Postgraduate diploma collaborative assignment: Implications for ...

African Journals Online (AJOL)

Postgraduate diploma collaborative assignment: Implications for ESL students ... and collaborative teaching/learning model involving the major course convenors. ... The quality of the work and mood of all concerned improved tremendously.

Automated backbone assignment of labeled proteins using the threshold accepting algorithm

International Nuclear Information System (INIS)

Leutner, Michael; Gschwind, Ruth M.; Liermann, Jens; Schwarz, Christian; Gemmecker, Gerd; Kessler, Horst

1998-01-01

The sequential assignment of backbone resonances is the first step in the structure determination of proteins by heteronuclear NMR. For larger proteins, an assignment strategy based on proton side-chain information is no longer suitable for the use in an automated procedure. Our program PASTA (Protein ASsignment by Threshold Accepting) is therefore designed to partially or fully automate the sequential assignment of proteins, based on the analysis of NMR backbone resonances plus C β information. In order to overcome the problems caused by peak overlap and missing signals in an automated assignment process, PASTA uses threshold accepting, a combinatorial optimization strategy, which is superior to simulated annealing due to generally faster convergence and better solutions. The reliability of this algorithm is shown by reproducing the complete sequential backbone assignment of several proteins from published NMR data. The robustness of the algorithm against misassigned signals, noise, spectral overlap and missing peaks is shown by repeating the assignment with reduced sequential information and increased chemical shift tolerances. The performance of the program on real data is finally demonstrated with automatically picked peak lists of human nonpancreatic synovial phospholipase A 2 , a protein with 124 residues

Assigning spectra of chaotic molecules with diabatic correlation diagrams

International Nuclear Information System (INIS)

Rose, J.P.; Kellman, M.E.

1996-01-01

An approach for classifying and organizing spectra of highly excited vibrational states of molecules is investigated. As a specific example, we analyze the spectrum of an effective spectroscopic fitting Hamiltonian for H 2 O. In highly excited spectra, multiple resonance couplings and anharmonicity interact to give branching of the N original normal modes into new anharmonic modes, accompanied by the onset of widespread chaos. The anharmonic modes are identified by means of a bifurcation analysis of the spectroscopic Hamiltonian. A diabatic correlation diagram technique is developed to assign the levels with approximate open-quote open-quote dynamical close-quote close-quote quantum numbers corresponding to the dynamics determined from the bifurcation analysis. The resulting assignment shows significant disturbance from the conventional spectral pattern organization into sequences and progressions. The open-quote open-quote dynamical close-quote close-quote assignment is then converted into an assignment in terms of open-quote open-quote nominal close-quote close-quote quantum numbers that function like the N normal mode quantum numbers at low energy. The nominal assignments are used to reconstruct, as much as possible, an organization of the spectrum resembling the usual separation into sequences and progressions. copyright 1996 American Institute of Physics

Parentage assignment of progeny in mixed milt fertilization of ...

African Journals Online (AJOL)

Administrator

2011-06-13

Jun 13, 2011 ... individuals. Overall, 98.8% of progeny were assigned to their parents using Family Assignment. Program (FAP). Selection of hyper-variable microsatellites in Caspian brown trout to identify unique alleles was effective for unambiguous parentage determination and estimation of genetic diversity in this study.

Integrating Academic Journal Review Assignments into a Graduate Business Leadership Course

Science.gov (United States)

Schultz, Jennifer L.; Agrimonti, Lisa M.; Higbee, Jeanne L.

2016-01-01

Graduate course assignments that are pragmatic, challenging, scaffold prior learning, and support academic career aspirations can be difficult to create and even more problematic to assess for even the most experienced faculty. This paper presents a class assignment that incorporated a real-world journal reviewing assignment into an elective…

20 CFR 422.104 - Who can be assigned a social security number.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Who can be assigned a social security number... General Procedures § 422.104 Who can be assigned a social security number. (a) Persons eligible for SSN assignment. We can assign you a social security number if you meet the evidence requirements in § 422.107 and...

32 CFR 644.396 - Assignment of personnel to administer.

Science.gov (United States)

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Assignment of personnel to administer. 644.396... PROPERTY REAL ESTATE HANDBOOK Disposal Predisposal Action § 644.396 Assignment of personnel to administer... responsible representative to each installation, or group of installations, to act under his staff supervision...

A Poster Assignment Connects Information Literacy and Writing Skills

Science.gov (United States)

Waters, Natalie

2015-01-01

This paper describes the implementation of a poster assignment in a writing and information literacy course required for undergraduate Life Sciences and Environmental Biology majors with the Faculty of Agricultural and Environmental Sciences at McGill University. The assignment was introduced in response to weaknesses identified through course…

42 CFR 421.114 - Assignment and reassignment of providers by CMS.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Assignment and reassignment of providers by CMS. 421.114 Section 421.114 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH... Assignment and reassignment of providers by CMS. CMS may assign or reassign any provider to any intermediary...

28 CFR 0.153 - Selection and assignment of employees for training.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Selection and assignment of employees for... Selection and assignment of employees for training. The Director of the Federal Bureau of Investigation, the....S.C. 4109, with respect to the selection and assignment of employees for training by, in, or through...

26 CFR 1.401(a)-13 - Assignment or alienation of benefits.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Assignment or alienation of benefits. 1.401(a...)-13 Assignment or alienation of benefits. (a) Scope of the regulations. This section applies only to..., provided for employer contributions. (b) No assignment or alienation—(1) General rule. Under section 401(a...

Towards unsupervised polyaromatic hydrocarbons structural assignment from SA-TIMS-FTMS data.

Science.gov (United States)

Benigni, Paolo; Marin, Rebecca; Fernandez-Lima, Francisco

2015-10-01

With the advent of high resolution ion mobility analyzers and their coupling to ultrahigh resolution mass spectrometers, there is a need to further develop a theoretical workflow capable of correlating experimental accurate mass and mobility measurements with tridimensional candidate structures. In the present work, a general workflow is described for unsupervised tridimensional structural assignment based on accurate mass measurements, mobility measurements, in silico 2D-3D structure generation, and theoretical mobility calculations. In particular, the potential of this workflow will be shown for the analysis of polyaromatic hydrocarbons from Coal Tar SRM 1597a using selected accumulation - trapped ion mobility spectrometry (SA-TIMS) coupled to Fourier transform-ion cyclotron resonance mass spectrometry (FT-ICR MS). The proposed workflow can be adapted to different IMS scenarios, can utilize different collisional cross-section calculators and has the potential to include MS n and IMS n measurements for faster and more accurate tridimensional structural assignment.

Method and system for assigning a confidence metric for automated determination of optic disc location

Science.gov (United States)

Karnowski, Thomas P [Knoxville, TN; Tobin, Jr., Kenneth W.; Muthusamy Govindasamy, Vijaya Priya [Knoxville, TN; Chaum, Edward [Memphis, TN

2012-07-10

A method for assigning a confidence metric for automated determination of optic disc location that includes analyzing a retinal image and determining at least two sets of coordinates locating an optic disc in the retinal image. The sets of coordinates can be determined using first and second image analysis techniques that are different from one another. An accuracy parameter can be calculated and compared to a primary risk cut-off value. A high confidence level can be assigned to the retinal image if the accuracy parameter is less than the primary risk cut-off value and a low confidence level can be assigned to the retinal image if the accuracy parameter is greater than the primary risk cut-off value. The primary risk cut-off value being selected to represent an acceptable risk of misdiagnosis of a disease having retinal manifestations by the automated technique.

DNATCO: assignment of DNA conformers at dnatco.org.

Science.gov (United States)

Černý, Jiří; Božíková, Paulína; Schneider, Bohdan

2016-07-08

The web service DNATCO (dnatco.org) classifies local conformations of DNA molecules beyond their traditional sorting to A, B and Z DNA forms. DNATCO provides an interface to robust algorithms assigning conformation classes called NTC: to dinucleotides extracted from DNA-containing structures uploaded in PDB format version 3.1 or above. The assigned dinucleotide NTC: classes are further grouped into DNA structural alphabet NTA: , to the best of our knowledge the first DNA structural alphabet. The results are presented at two levels: in the form of user friendly visualization and analysis of the assignment, and in the form of a downloadable, more detailed table for further analysis offline. The website is free and open to all users and there is no login requirement. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

Selections from the ABC 2014 Annual Conference, Philadelphia, Pennsylvania: Let Favorite Assignments Ring: Sharpening Communication Tools and Self and Career Development

Science.gov (United States)

Whalen, D. Joel; Crenshaw, Cheri; Ortiz, Lorelei A.; Vik, Gretchen N.; Meredith, Michael J.; Deambrosi, Alfredo; Luck, Susan L.; Rausch, Georgi; Canas, Kathryn; Hicks, Nancy; Newman, Amy; Hofacker, Cynthia M.; Webb, Susan Hall; Zizik, Catherine H.

2015-01-01

This article, the first of a two-part series, catalogs teaching innovations from the 2014 Association for Business Communication Annual Conference. These 12 assignments debuted during two "My Favorite Assignment" sessions. Learning experiences included job-seeking skills--résumé writing, writing job applications, sharpening interview…

Effective Homework Assignments. Research Brief

Science.gov (United States)

Cooper, Harris

2008-01-01

Perhaps more than any question other than "How much time should students spend doing homework?" parents and educators want to know, "What kinds of homework assignments are most effective?" Clearly, the answers to this question vary according to many factors, especially the developmental level of students and the topic area. Generally, answers are…

Dynamic traffic assignment : genetic algorithms approach

Science.gov (United States)

1997-01-01

Real-time route guidance is a promising approach to alleviating congestion on the nations highways. A dynamic traffic assignment model is central to the development of guidance strategies. The artificial intelligence technique of genetic algorithm...

On some special cases of the restricted assignment problem

NARCIS (Netherlands)

Wang, C. (Chao); R.A. Sitters (René)

2016-01-01

textabstractWe consider some special cases of the restricted assignment problem. In this scheduling problem on parallel machines, any job j can only be assigned to one of the machines in its given subset Mj of machines. We give an LP-formulation for the problem with two job sizes and show that it

13 CFR 500.210 - Assignment or transfer of loans.

Science.gov (United States)

2010-01-01

... has the effect of distributing the risks of the credit among other Lenders if: (i) Neither the loan... be modified, assigned, conveyed, sold or otherwise transferred by the Lender, in whole or in part... assignment or transfer of less than 100 percent of a Lender's interest in the Loan Documents and Guarantee...

Minutes of the 28th annual plutonium sample exchange meeting. Part I: isotopic sample exchange

International Nuclear Information System (INIS)

1984-01-01

Contents of this publication include the following: list of participating laboratories; agenda; attendees; minutes of October 24 meeting; and handout materials supplied by speakers. The handout materials cover the following: interlaboratory comparisons of plutonium isotope ratios. The plutonium ratios considered are 240/239, 241/239, 242/239, 238/239, 239/240, 241/240, 242/240, and 238/240; carbon, uranium, iron, and nickel data; mass spectroscopy data; determination of plutonium 241 half-life; review of plutonium overplating sample loading technique; on-line measurement evaluation system for isotopic analysis; and description of a new thermal ionization mass spectrometer

A parametric visualization software for the assignment problem

Directory of Open Access Journals (Sweden)

Papamanthou Charalampos

2005-01-01

Full Text Available In this paper we present a parametric visualization software used to assist the teaching of the Network Primal Simplex Algorithm for the assignment problem (AP. The assignment problem is a special case of the balanced transportation problem. The main functions of the algorithm and design techniques are also presented. Through this process, we aim to underline the importance and necessity of using such educational methods in order to improve the teaching of Computer Algorithms.

Single Machine Scheduling and Due Date Assignment with Past-Sequence-Dependent Setup Time and Position-Dependent Processing Time

Directory of Open Access Journals (Sweden)

Chuan-Li Zhao

2014-01-01

Full Text Available This paper considers single machine scheduling and due date assignment with setup time. The setup time is proportional to the length of the already processed jobs; that is, the setup time is past-sequence-dependent (p-s-d. It is assumed that a job's processing time depends on its position in a sequence. The objective functions include total earliness, the weighted number of tardy jobs, and the cost of due date assignment. We analyze these problems with two different due date assignment methods. We first consider the model with job-dependent position effects. For each case, by converting the problem to a series of assignment problems, we proved that the problems can be solved in On4 time. For the model with job-independent position effects, we proved that the problems can be solved in On3 time by providing a dynamic programming algorithm.

The Utility of Writing Assignments in Undergraduate Bioscience

Science.gov (United States)

Libarkin, Julie; Ording, Gabriel

2012-01-01

We tested the hypothesis that engagement in a few, brief writing assignments in a nonmajors science course can improve student ability to convey critical thought about science. A sample of three papers written by students (n = 30) was coded for presence and accuracy of elements related to scientific writing. Scores for different aspects of scientific writing were significantly correlated, suggesting that students recognized relationships between components of scientific thought. We found that students' ability to write about science topics and state conclusions based on data improved over the course of three writing assignments, while the abilities to state a hypothesis and draw clear connections between human activities and environmental impacts did not improve. Three writing assignments generated significant change in student ability to write scientifically, although our results suggest that three is an insufficient number to generate complete development of scientific writing skills. PMID:22383616

A search asymmetry reversed by figure-ground assignment.

Science.gov (United States)

Humphreys, G W; Müller, H

2000-05-01

We report evidence demonstrating that a search asymmetry favoring concave over convex targets can be reversed by altering the figure-ground assignment of edges in shapes. Visual search for a concave target among convex distractors is faster than search for a convex target among concave distractors (a search asymmetry). By using shapes with ambiguous local figure-ground relations, we demonstrated that search can be efficient (with search slopes around 10 ms/item) or inefficient (with search slopes around 30-40 ms/item) with the same stimuli, depending on whether edges are assigned to concave or convex "figures." This assignment process can operate in a top-down manner, according to the task set. The results suggest that attention is allocated to spatial regions following the computation of figure-ground relations in parallel across the elements present. This computation can also be modulated by top-down processes.

4D experiments measured with APSY for automated backbone resonance assignments of large proteins

International Nuclear Information System (INIS)

Krähenbühl, Barbara; Boudet, Julien; Wider, Gerhard

2013-01-01

Detailed structural and functional characterization of proteins by solution NMR requires sequence-specific resonance assignment. We present a set of transverse relaxation optimization (TROSY) based four-dimensional automated projection spectroscopy (APSY) experiments which are designed for resonance assignments of proteins with a size up to 40 kDa, namely HNCACO, HNCOCA, HNCACB and HN(CO)CACB. These higher-dimensional experiments include several sensitivity-optimizing features such as multiple quantum parallel evolution in a ‘just-in-time’ manner, aliased off-resonance evolution, evolution-time optimized APSY acquisition, selective water-handling and TROSY. The experiments were acquired within the concept of APSY, but they can also be used within the framework of sparsely sampled experiments. The multidimensional peak lists derived with APSY provided chemical shifts with an approximately 20 times higher precision than conventional methods usually do, and allowed the assignment of 90 % of the backbone resonances of the perdeuterated primase-polymerase ORF904, which contains 331 amino acid residues and has a molecular weight of 38.4 kDa.

14 CFR 1245.109 - Assignment of title to NASA.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Assignment of title to NASA. 1245.109... INTELLECTUAL PROPERTY RIGHTS Patent Waiver Regulations § 1245.109 Assignment of title to NASA. (a) The instrument of waiver set forth in § 1245.115(c) shall be voided by NASA with respect to the domestic title to...

Cue competition affects temporal dynamics of edge-assignment in human visual cortex.

Science.gov (United States)

Brooks, Joseph L; Palmer, Stephen E

2011-03-01

Edge-assignment determines the perception of relative depth across an edge and the shape of the closer side. Many cues determine edge-assignment, but relatively little is known about the neural mechanisms involved in combining these cues. Here, we manipulated extremal edge and attention cues to bias edge-assignment such that these two cues either cooperated or competed. To index their neural representations, we flickered figure and ground regions at different frequencies and measured the corresponding steady-state visual-evoked potentials (SSVEPs). Figural regions had stronger SSVEP responses than ground regions, independent of whether they were attended or unattended. In addition, competition and cooperation between the two edge-assignment cues significantly affected the temporal dynamics of edge-assignment processes. The figural SSVEP response peaked earlier when the cues causing it cooperated than when they competed, but sustained edge-assignment effects were equivalent for cooperating and competing cues, consistent with a winner-take-all outcome. These results provide physiological evidence that figure-ground organization involves competitive processes that can affect the latency of figural assignment.

Task assignment and coaching

OpenAIRE

Dominguez-Martinez, S.

2009-01-01

An important task of a manager is to motivate her subordinates. One way in which a manager can give incentives to junior employees is through the assignment of tasks. How a manager allocates tasks in an organization, provides information to the junior employees about his ability. Without coaching from a manager, the junior employee only has information about his past performance. Based on his past performance, a talented junior who has performed a difficult task sometimes decides to leave the...

An up-link power control for demand assignment International Business Satellite Communications Network

Science.gov (United States)

Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio

Up-link power control (UPC) is one of the essential technologies to provide efficient satellite communication systems operated at frequency bands above 10 GHz. A simple and cost-effective UPC scheme applicable to a demand assignment international business satellite communications system has been developed. This paper presents the UPC scheme, including the hardware implementation and its performance.

Optimizing and accelerating the assignation of lineages in Mycobacterium tuberculosis using novel alternative single-tube assays.

Directory of Open Access Journals (Sweden)

María Carcelén

Full Text Available The assignation of lineages in Mycobacterium tuberculosis (MTB provides valuable information for evolutionary and phylogeographic studies and makes for more accurate knowledge of the distribution of this pathogen worldwide. Differences in virulence have also been found for certain lineages. MTB isolates were initially assigned to lineages based on data obtained from genotyping techniques, such as spoligotyping or MIRU-VNTR analysis, some of which are more suitable for molecular epidemiology studies. However, since these methods are subject to a certain degree of homoplasy, other criteria have been chosen to assign lineages. These are based on targeting robust and specific SNPs for each lineage. Here, we propose two newly designed multiplex targeting methods-both of which are single-tube tests-to optimize the assignation of the six main lineages in MTB. The first method is based on ASO-PCR and offers an inexpensive and easy-to-implement assay for laboratories with limited resources. The other, which is based on SNaPshot, enables more refined standardized assignation of lineages for laboratories with better resources. Both methods performed well when assigning lineages from cultured isolates from a control panel, a test panel, and a problem panel from an unrelated population, Mexico, which included isolates in which standard genotyping was not able to classify lineages. Both tests were also able to assign lineages from stored isolates, without the need for subculture or purification of DNA, and even directly from clinical specimens with a medium-high bacilli burden. Our assays could broaden the contexts where information on lineages can be acquired, thus enabling us to quickly update data from retrospective collections and to merge data with those obtained at the time of diagnosis of a new TB case.

Implementing a cornerstone of culture change: Consistent staff assignment in VHA community living centers.

Science.gov (United States)

Lemke, Sonne; Brennan, Penny L; SooHoo, Sonya; Schutte, Kathleen K

2017-08-01

In 2011, the Veterans Health Administration (VHA) began implementing consistent staff assignment in its nursing homes (called Community Living Centers or CLCs). Consistent assignment, a cornerstone of culture change, minimizes the number of staff who provide a resident's care. The present research assessed the level and stability of consistent assignment in units within VHA CLCs and identified unit characteristics related to implementation of this staff assignment model. Schedulers in 185 of 335 organizational units that make up VHA CLCs completed a Staffing Practices Survey. For the month prior to the survey, 53% of CLC units had full implementation of consistent assignment. Tracked back over time, 37% of CLC units had stable high consistent assignment, 29% had stable low consistent assignment, and 34% were variable. Units with stable high consistent assignment were most likely to use care teams with stable membership and to obtain staff input for care assignments. Schedulers in these units reported more positive experiences with consistent staff assignment and better unit functioning in terms of staff absences, complaints about workload fairness, and resolution of scheduling problems. Units with stable low and variable consistent assignment were similar in most of these respects; however, units with variable consistent assignment made greater use of stable care teams and were less likely to change assignments at a staff member's request. Overall, consistent assignment implementation was not related to unit size, nursing hours per resident day, or specialty focus. Findings can help guide consistent staff assignment implementation in VHA and community nursing homes. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

The impact of taxation on international assignment decisions: A principal-agent approach

OpenAIRE

Martini, Jan Thomas; Niemann, Rainer

2013-01-01

In many industries like management consulting, IT consulting, or construction highly qualified employees, i.e., experts or executive managers, have to be assigned to temporary projects. In firms with many employees and various different projects, this assignment decision involves a complex optimization procedure. Obviously, the employees’ productivities in the respective projects are crucial for the employer’s optimal assignment decision, but assignment can also be affected by risk-incent...

Automated Bug Assignment: Ensemble-based Machine Learning in Large Scale Industrial Contexts

OpenAIRE

Jonsson, Leif; Borg, Markus; Broman, David; Sandahl, Kristian; Eldh, Sigrid; Runeson, Per

2016-01-01

Bug report assignment is an important part of software maintenance. In particular, incorrect assignments of bug reports to development teams can be very expensive in large software development projects. Several studies propose automating bug assignment techniques using machine learning in open source software contexts, but no study exists for large-scale proprietary projects in industry. The goal of this study is to evaluate automated bug assignment techniques that are based on machine learni...

An integer programming model for gate assignment problem at airline terminals

Science.gov (United States)

Chun, Chong Kok; Nordin, Syarifah Zyurina

2015-05-01

In this paper, we concentrate on a gate assignment problem (GAP) at the airlines terminal. Our problem is to assign an arrival plane to a suitable gate. There are two considerations needed to take. One of its is passenger walking distance from arrival gate to departure gate while another consideration is the transport baggage distance from one gate to another. Our objective is to minimize the total distance between the gates that related to assign the arrival plane to the suitable gates. An integer linear programming (ILP) model is proposed to solve this gate assignment problem. We also conduct a computational experiment using CPLEX 12.1 solver in AIMMS 3.10 software to analyze the performance of the model. Results of the computational experiments are presented. The efficiency of flights assignment is depends on the ratio of the weight for both total passenger traveling distances and total baggage transport distances.

Web-Based Problem-Solving Assignment and Grading System

Science.gov (United States)

Brereton, Giles; Rosenberg, Ronald

2014-11-01

In engineering courses with very specific learning objectives, such as fluid mechanics and thermodynamics, it is conventional to reinforce concepts and principles with problem-solving assignments and to measure success in problem solving as an indicator of student achievement. While the modern-day ease of copying and searching for online solutions can undermine the value of traditional assignments, web-based technologies also provide opportunities to generate individualized well-posed problems with an infinite number of different combinations of initial/final/boundary conditions, so that the probability of any two students being assigned identical problems in a course is vanishingly small. Such problems can be designed and programmed to be: single or multiple-step, self-grading, allow students single or multiple attempts; provide feedback when incorrect; selectable according to difficulty; incorporated within gaming packages; etc. In this talk, we discuss the use of a homework/exam generating program of this kind in a single-semester course, within a web-based client-server system that ensures secure operation.

Lower region: a new cue for figure-ground assignment.

Science.gov (United States)

Vecera, Shaun P; Vogel, Edward K; Woodman, Geoffrey F

2002-06-01

Figure-ground assignment is an important visual process; humans recognize, attend to, and act on figures, not backgrounds. There are many visual cues for figure-ground assignment. A new cue to figure-ground assignment, called lower region, is presented: Regions in the lower portion of a stimulus array appear more figurelike than regions in the upper portion of the display. This phenomenon was explored, and it was demonstrated that the lower-region preference is not influenced by contrast, eye movements, or voluntary spatial attention. It was found that the lower region is defined relative to the stimulus display, linking the lower-region preference to pictorial depth perception cues. The results are discussed in terms of the environmental regularities that this new figure-ground cue may reflect.

Students' Understanding and Perceptions of Assigned Team Roles in a Classroom Laboratory Environment

Science.gov (United States)

Ott, Laura E.; Kephart, Kerrie; Stolle-McAllister, Kathleen; LaCourse, William R.

2018-01-01

Using a cooperative learning framework in a quantitative reasoning laboratory course, students were assigned to static teams of four in which they adopted roles that rotated regularly. The roles included: team leader, protocol manager, data recorder, and researcher. Using a mixed-methods approach, we investigated students' perceptions of the team…

Reptiles.

Science.gov (United States)

Naturescope, 1987

1987-01-01

Describes some of the characteristics of various reptiles. Contains teaching activities including making reptile number books and identification keys, flip-ups about cobras, puzzles involving graphing, and group presentations. Includes reproducible handouts to be used with some of the activities. (TW)

Understanding the Theory of Multiple Intelligences. Staff Workshop Handout

Science.gov (United States)

Early Childhood Today, 2005

2005-01-01

In his "Theory of Multiple Intelligences," Dr. Howard Gardner expands the concept of intelligence to include such areas as music, spatial relations, and interpersonal knowledge in addition to the traditional view of two intelligences--mathematical and linguistic. Using biological as well as cultural research, Gardner formulated a list of seven…

TSAR: a program for automatic resonance assignment using 2D cross-sections of high dimensionality, high-resolution spectra

Energy Technology Data Exchange (ETDEWEB)

Zawadzka-Kazimierczuk, Anna; Kozminski, Wiktor [University of Warsaw, Faculty of Chemistry (Poland); Billeter, Martin, E-mail: martin.billeter@chem.gu.se [University of Gothenburg, Biophysics Group, Department of Chemistry and Molecular Biology (Sweden)

2012-09-15

While NMR studies of proteins typically aim at structure, dynamics or interactions, resonance assignments represent in almost all cases the initial step of the analysis. With increasing complexity of the NMR spectra, for example due to decreasing extent of ordered structure, this task often becomes both difficult and time-consuming, and the recording of high-dimensional data with high-resolution may be essential. Random sampling of the evolution time space, combined with sparse multidimensional Fourier transform (SMFT), allows for efficient recording of very high dimensional spectra ({>=}4 dimensions) while maintaining high resolution. However, the nature of this data demands for automation of the assignment process. Here we present the program TSAR (Tool for SMFT-based Assignment of Resonances), which exploits all advantages of SMFT input. Moreover, its flexibility allows to process data from any type of experiments that provide sequential connectivities. The algorithm was tested on several protein samples, including a disordered 81-residue fragment of the {delta} subunit of RNA polymerase from Bacillus subtilis containing various repetitive sequences. For our test examples, TSAR achieves a high percentage of assigned residues without any erroneous assignments.

75 FR 55352 - Delegation of Authorities and Assignment of Responsibilities

Science.gov (United States)

2010-09-10

... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authorities and Assignment of Responsibilities Secretary's Order 5-2010 Subject: Delegation of Authorities and Assignment of Responsibilities to... rather than the Administrator, WHD (see also Secretary's Order 3-2010). 5. Delegations of Authority and...

11 CFR 109.33 - May a political party committee assign its coordinated party expenditure authority to another...

Science.gov (United States)

2010-01-01

... Elections FEDERAL ELECTION COMMISSION GENERAL COORDINATED AND INDEPENDENT EXPENDITURES (2 U.S.C. 431(17... 11 Federal Elections 1 2010-01-01 2010-01-01 false May a political party committee assign its... committee includes a subordinate committee of a State committee and includes a district or local committee...

ZAP: a distributed channel assignment algorithm for cognitive radio networks

Directory of Open Access Journals (Sweden)

Munaretto Anelise

2011-01-01

Full Text Available Abstract We propose ZAP, an algorithm for the distributed channel assignment in cognitive radio (CR networks. CRs are capable of identifying underutilized licensed bands of the spectrum, allowing their reuse by secondary users without interfering with primary users. In this context, efficient channel assignment is challenging as ideally it must be simple, incur acceptable communication overhead, provide timely response, and be adaptive to accommodate frequent changes in the network. Another challenge is the optimization of network capacity through interference minimization. In contrast to related work, ZAP addresses these challenges with a fully distributed approach based only on local (neighborhood knowledge, while significantly reducing computational costs and the number of messages required for channel assignment. Simulations confirm the efficiency of ZAP in terms of (i the performance tradeoff between different metrics and (ii the fast achievement of a suitable assignment solution regardless of network size and density.

Strategy-Proof Assignment Of Multiple Resources

DEFF Research Database (Denmark)

Erlanson, Albin; Szwagrzak, Karol

2015-01-01

We examine the strategy-proof allocation of multiple resources; an application is the assignment of packages of tasks, workloads, and compensations among the members of an organization. In the domain of multidimensional single-peaked preferences, we find that any allocation mechanism obtained by ...

Statistical aspects of optimal treatment assignment

NARCIS (Netherlands)

van der Linden, Willem J.

The issues of treatment assignment is ordinarily dealt with within the framework of testing aptitude treatment interaction (ATI) hypothesis. ATI research mostly uses linear regression techniques, and an ATI exists when the aptitude treatment (AT) regression lines cross each other within the relevant

Resonance assignment of the NMR spectra of disordered proteins using a multi-objective non-dominated sorting genetic algorithm

International Nuclear Information System (INIS)

Yang, Yu; Fritzsching, Keith J.; Hong, Mei

2013-01-01

A multi-objective genetic algorithm is introduced to predict the assignment of protein solid-state NMR (SSNMR) spectra with partial resonance overlap and missing peaks due to broad linewidths, molecular motion, and low sensitivity. This non-dominated sorting genetic algorithm II (NSGA-II) aims to identify all possible assignments that are consistent with the spectra and to compare the relative merit of these assignments. Our approach is modeled after the recently introduced Monte-Carlo simulated-annealing (MC/SA) protocol, with the key difference that NSGA-II simultaneously optimizes multiple assignment objectives instead of searching for possible assignments based on a single composite score. The multiple objectives include maximizing the number of consistently assigned peaks between multiple spectra (“good connections”), maximizing the number of used peaks, minimizing the number of inconsistently assigned peaks between spectra (“bad connections”), and minimizing the number of assigned peaks that have no matching peaks in the other spectra (“edges”). Using six SSNMR protein chemical shift datasets with varying levels of imperfection that was introduced by peak deletion, random chemical shift changes, and manual peak picking of spectra with moderately broad linewidths, we show that the NSGA-II algorithm produces a large number of valid and good assignments rapidly. For high-quality chemical shift peak lists, NSGA-II and MC/SA perform similarly well. However, when the peak lists contain many missing peaks that are uncorrelated between different spectra and have chemical shift deviations between spectra, the modified NSGA-II produces a larger number of valid solutions than MC/SA, and is more effective at distinguishing good from mediocre assignments by avoiding the hazard of suboptimal weighting factors for the various objectives. These two advantages, namely diversity and better evaluation, lead to a higher probability of predicting the correct

Resonance assignment of the NMR spectra of disordered proteins using a multi-objective non-dominated sorting genetic algorithm.

Science.gov (United States)

Yang, Yu; Fritzsching, Keith J; Hong, Mei

2013-11-01

A multi-objective genetic algorithm is introduced to predict the assignment of protein solid-state NMR (SSNMR) spectra with partial resonance overlap and missing peaks due to broad linewidths, molecular motion, and low sensitivity. This non-dominated sorting genetic algorithm II (NSGA-II) aims to identify all possible assignments that are consistent with the spectra and to compare the relative merit of these assignments. Our approach is modeled after the recently introduced Monte-Carlo simulated-annealing (MC/SA) protocol, with the key difference that NSGA-II simultaneously optimizes multiple assignment objectives instead of searching for possible assignments based on a single composite score. The multiple objectives include maximizing the number of consistently assigned peaks between multiple spectra ("good connections"), maximizing the number of used peaks, minimizing the number of inconsistently assigned peaks between spectra ("bad connections"), and minimizing the number of assigned peaks that have no matching peaks in the other spectra ("edges"). Using six SSNMR protein chemical shift datasets with varying levels of imperfection that was introduced by peak deletion, random chemical shift changes, and manual peak picking of spectra with moderately broad linewidths, we show that the NSGA-II algorithm produces a large number of valid and good assignments rapidly. For high-quality chemical shift peak lists, NSGA-II and MC/SA perform similarly well. However, when the peak lists contain many missing peaks that are uncorrelated between different spectra and have chemical shift deviations between spectra, the modified NSGA-II produces a larger number of valid solutions than MC/SA, and is more effective at distinguishing good from mediocre assignments by avoiding the hazard of suboptimal weighting factors for the various objectives. These two advantages, namely diversity and better evaluation, lead to a higher probability of predicting the correct assignment for a

Privacy-Preserving Task Assignment in Spatial Crowdsourcing

KAUST Repository

Liu, An; Li, Zhi-Xu; Liu, Guan-Feng; Zheng, Kai; Zhang, Min; Li, Qing; Zhang, Xiangliang

2017-01-01

untrusted SC systems. In this paper, we study the problem of assigning workers to tasks in a way that location privacy for both workers and task requesters is preserved. We first combine the Paillier cryptosystem with Yao’s garbled circuits to construct a secure protocol that assigns the nearest worker to a task. Considering that this protocol cannot scale to a large number of workers, we then make use of Geohash, a hierarchical spatial index to design a more efficient protocol that can securely find approximate nearest workers. We theoretically show that these two protocols are secure against semi-honest adversaries. Through extensive experiments on two real-world datasets, we demonstrate the efficiency and effectiveness of our protocols.

A feedback model of figure-ground assignment.

Science.gov (United States)

Domijan, Drazen; Setić, Mia

2008-05-30

A computational model is proposed in order to explain how bottom-up and top-down signals are combined into a unified perception of figure and background. The model is based on the interaction between the ventral and the dorsal stream. The dorsal stream computes saliency based on boundary signals provided by the simple and the complex cortical cells. Output from the dorsal stream is projected to the surface network which serves as a blackboard on which the surface representation is formed. The surface network is a recurrent network which segregates different surfaces by assigning different firing rates to them. The figure is labeled by the maximal firing rate. Computer simulations showed that the model correctly assigns figural status to the surface with a smaller size, a greater contrast, convexity, surroundedness, horizontal-vertical orientation and a higher spatial frequency content. The simple gradient of activity in the dorsal stream enables the simulation of the new principles of the lower region and the top-bottom polarity. The model also explains how the exogenous attention and the endogenous attention may reverse the figural assignment. Due to the local excitation in the surface network, neural activity at the cued region will spread over the whole surface representation. Therefore, the model implements the object-based attentional selection.

AN EVOLUTIONARY ALGORITHM FOR CHANNEL ASSIGNMENT PROBLEM IN WIRELESS MOBILE NETWORKS

Directory of Open Access Journals (Sweden)

Yee Shin Chia

2012-12-01

Full Text Available The channel assignment problem in wireless mobile network is the assignment of appropriate frequency spectrum to incoming calls while maintaining a satisfactory level of electromagnetic compatibility (EMC constraints. An effective channel assignment strategy is important due to the limited capacity of frequency spectrum in wireless mobile network. Most of the existing channel assignment strategies are based on deterministic methods. In this paper, an adaptive genetic algorithm (GA based channel assignment strategy is introduced for resource management and to reduce the effect of EMC interferences. The most significant advantage of the proposed optimization method is its capability to handle both the reassignment of channels for existing calls as well as the allocation of channel to a new incoming call in an adaptive process to maximize the utility of the limited resources. It is capable to adapt the population size to the number of eligible channels for a particular cell upon new call arrivals to achieve reasonable convergence speed. The MATLAB simulation on a 49-cells network model for both uniform and nonuniform call traffic distributions showed that the proposed channel optimization method can always achieve a lower average new incoming call blocking probability compared to the deterministic based channel assignment strategy.

The "Outsider/Insider" Assignment: A Pedagogical Innovation for Teaching Cross-Cultural Understanding

Science.gov (United States)

Garcia, Angela Cora

2014-01-01

In this paper, I describe an innovative assignment for teaching undergraduate students cross-cultural understanding. The Outsider/Insider assignment simultaneously teaches facts about cultural difference and skills for managing cross-cultural encounters. Briefly, the assignment is to write two short papers, one in which the student describes a…

Moving beyond "Bookish Knowledge": Using Film-Based Assignments to Promote Deep Learning

Science.gov (United States)

Olson, Joann S.; Autry, Linda; Moe, Jeffry

2016-01-01

This article investigates the effectiveness of a film-based assignment given to adult learners in a graduate-level group counseling class. Semi-structured interviews were conducted with four students; data analysis suggested film-based assignments may promote deep approaches to learning (DALs). Participants indicated the assignment helped them…

Developing Problem Solving and Communication Skills through Memo Assignments in a Management Science Course

Science.gov (United States)

Williams, Julie Ann Stuart; Reid, Randall C.

2010-01-01

The authors describe how to structure a memo format for homework assignments in which a manager requests analysis of a particular issue from the student. The student must respond with a memo stating a recommendation and describing the solution approach. The results from using the memo format include improved student performance and professional…

Tabu search for target-radar assignment

DEFF Research Database (Denmark)

Hindsberger, Magnus; Vidal, Rene Victor Valqui

2000-01-01

In the paper the problem of assigning air-defense illumination radars to enemy targets is presented. A tabu search metaheuristic solution is described and the results achieved are compared to those of other heuristic approaches, implementation and experimental aspects are discussed. It is argued ...

Semi-infinite assignment and transportation games

NARCIS (Netherlands)

Timmer, Judith B.; Sánchez-Soriano, Joaqu´ın; Llorca, Navidad; Tijs, Stef; Goberna, Miguel A.; López, Marco A.

2001-01-01

Games corresponding to semi-infinite transportation and related assignment situations are studied. In a semi-infinite transportation situation, one aims at maximizing the profit from the transportation of a certain good from a finite number of suppliers to an infinite number of demanders. An

Single machine scheduling with slack due dates assignment

Science.gov (United States)

Liu, Weiguo; Hu, Xiangpei; Wang, Xuyin

2017-04-01

This paper considers a single machine scheduling problem in which each job is assigned an individual due date based on a common flow allowance (i.e. all jobs have slack due date). The goal is to find a sequence for jobs, together with a due date assignment, that minimizes a non-regular criterion comprising the total weighted absolute lateness value and common flow allowance cost, where the weight is a position-dependent weight. In order to solve this problem, an ? time algorithm is proposed. Some extensions of the problem are also shown.

Stoplight Grid: a color-coded visual system for per diem staff assignment.

Science.gov (United States)

Ernst, P

1989-02-01

What is the best way to appropriately assign per diem nursing personnel? The author describes a systematic approach to per diem staff assignment called the Stoplight Grid. The Stoplight Grid correlates staff skills and preferences with unit needs and integrates this data into a color-coded system for staff assignment.

7 CFR 929.150 - Transfer or assignment of sales history.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Transfer or assignment of sales history. 929.150... MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE... Transfer or assignment of sales history. (a) If indebtedness is incurred with regard to the acreage to...

Assigning Main Orientation to an EOH Descriptor on Multispectral Images.

Science.gov (United States)

Li, Yong; Shi, Xiang; Wei, Lijun; Zou, Junwei; Chen, Fang

2015-07-01

This paper proposes an approach to compute an EOH (edge-oriented histogram) descriptor with main orientation. EOH has a better matching ability than SIFT (scale-invariant feature transform) on multispectral images, but does not assign a main orientation to keypoints. Alternatively, it tends to assign the same main orientation to every keypoint, e.g., zero degrees. This limits EOH to matching keypoints between images of translation misalignment only. Observing this limitation, we propose assigning to keypoints the main orientation that is computed with PIIFD (partial intensity invariant feature descriptor). In the proposed method, SIFT keypoints are detected from images as the extrema of difference of Gaussians, and every keypoint is assigned to the main orientation computed with PIIFD. Then, EOH is computed for every keypoint with respect to its main orientation. In addition, an implementation variant is proposed for fast computation of the EOH descriptor. Experimental results show that the proposed approach performs more robustly than the original EOH on image pairs that have a rotation misalignment.

Selections from the ABC 2016 Annual Conference, Albuquerque, New Mexico: Bright as Stars in the Albuquerque Desert Sky: Classroom-Tested Business Communication Assignments

Science.gov (United States)

Whalen, D. Joel, Ed.

2017-01-01

This article, the first of a two-part series, presents 13 teaching innovations debuted at the 2016 Association for Business Communication's annual conference. The second edition of "My Favorite Assignment" will be published in the fall 2017 "Business and Professional Communication Quarterly". Assignments include international…

PARAssign-paramagnetic NMR assignments of protein nuclei on the basis of pseudocontact shifts

Energy Technology Data Exchange (ETDEWEB)

Skinner, Simon P., E-mail: skinnersp@chem.leidenuniv.nl [Leiden University, Gorlaeus Laboratories, Leiden Institute of Chemistry (Netherlands); Moshev, Mois, E-mail: mois@monomon.me [Leiden University, Leiden Institute of Advanced Computer Science (Netherlands); Hass, Mathias A. S., E-mail: hassmas@chem.leidenuniv.nl; Ubbink, Marcellus, E-mail: m.ubbink@chem.leidenuniv.nl [Leiden University, Gorlaeus Laboratories, Leiden Institute of Chemistry (Netherlands)

2013-04-15

The use of paramagnetic NMR data for the refinement of structures of proteins and protein complexes is widespread. However, the power of paramagnetism for protein assignment has not yet been fully exploited. PARAssign is software that uses pseudocontact shift data derived from several paramagnetic centers attached to the protein to obtain amide and methyl assignments. The ability of PARAssign to perform assignment when the positions of the paramagnetic centers are known and unknown is demonstrated. PARAssign has been tested using synthetic data for methyl assignment of a 47 kDa protein, and using both synthetic and experimental data for amide assignment of a 14 kDa protein. The complex fitting space involved in such an assignment procedure necessitates that good starting conditions are found, both regarding placement and strength of paramagnetic centers. These starting conditions are obtained through automated tensor placement and user-defined tensor parameters. The results presented herein demonstrate that PARAssign is able to successfully perform resonance assignment in large systems with a high degree of reliability. This software provides a method for obtaining the assignments of large systems, which may previously have been unassignable, by using 2D NMR spectral data and a known protein structure.

LOW POWER RACE-FREE STATE ASSIGNMENT OF AN ASYNGHRONOUS AUTOMATON

Directory of Open Access Journals (Sweden)

Yu. V. Pottosin

2015-01-01

Full Text Available The problem of a race free state assignment of an asynchronous automaton is considered. A method for the state assignment is suggested that provides the minimization of the number and theswitching activity of the memory elements along with the elimination of the critical races betweenthem.

Capacity constrained assignment in spatial databases

DEFF Research Database (Denmark)

U, Leong Hou; Yiu, Man Lung; Mouratidis, Kyriakos

2008-01-01

large to fit in main memory. Motivated by this fact, we propose efficient algorithms for optimal assignment that employ novel edge-pruning strategies, based on the spatial properties of the problem. Additionally, we develop approximate (i.e., suboptimal) CCA solutions that provide a trade-off between...

A Method Based on Dial's Algorithm for Multi-time Dynamic Traffic Assignment

Directory of Open Access Journals (Sweden)

Rongjie Kuang

2014-03-01

Full Text Available Due to static traffic assignment has poor performance in reflecting actual case and dynamic traffic assignment may incurs excessive compute cost, method of multi-time dynamic traffic assignment combining static and dynamic traffic assignment balances factors of precision and cost effectively. A method based on Dial's logit algorithm is proposed in the article to solve the dynamic stochastic user equilibrium problem in dynamic traffic assignment. Before that, a fitting function that can proximately reflect overloaded traffic condition of link is proposed and used to give corresponding model. Numerical example is given to illustrate heuristic procedure of method and to compare results with one of same example solved by other literature's algorithm. Results show that method based on Dial's algorithm is preferable to algorithm from others.

Students' Understanding and Perceptions of Assigned Team Roles in a Classroom Laboratory Environment

Science.gov (United States)

Ott, Laura E.; Kephart, Kerrie; Stolle-McAllister, Kathleen; LaCourse, William R.

2018-01-01

Using a cooperative learning framework in a quantitative reasoning laboratory course, students were assigned to static teams of four in which they adopted roles that rotated regularly. The roles included: team leader, protocol manager, data recorder, and researcher. Using a mixed-methods approach, we investigated students' perceptions of the team roles and specifically addressed students' understanding of the roles, students' beliefs in their ability to enact the roles, and whether working with assigned team roles supported the teams to work effectively and cohesively. Although students expressed confidence in their understanding of the team roles, their understanding differed from the initial descriptions. This suggests that students' understanding of team roles may be influenced by a variety of factors, including their experiences within their teams. Students also reported that some roles appeared to lack a purpose, implying that for roles to be successful, they must have a clear purpose. Finally, the fact that many students reported ignoring the team roles suggests that students do not perceive roles as a requirement for team productivity and cohesion. On the basis of these findings, we provide recommendations for instructors wishing to establish a classroom group laboratory environment. PMID:29681667

Effectiveness of author-assigned keywords to INIS indexing

International Nuclear Information System (INIS)

Yokoo, Hiroshi; Takahashi, Satoko; Habara, Tadashi

1977-01-01

A test was carried out on the quality of indexing data which is based only upon author-assigned keywords in order to appreciate effectiveness of the keywords. As measures of the quality, the retrievability and the consistency of the indexing data were evaluated by comparison with the case of the conventional indexing method under the circumstances of the INIS descriptor assignment to the journal articles of the Atomic Energy Society of Japan. The indexing consistency obtained was approximately 0.61 on an average (or 0.66 when the narrower-broader hierarchical relations were regarded as consistent ones). Of the hit, noise, or total documents retrieved with the conventional indexing data, 0.86, 0.27, or 0.71, respectively, were retrievable with the keywords-based indexing data. From the results the recall ratio for the keywords-based indexing is estimated to be no less than 0.86 of that for the conventional indexing method, and the consistency of the hit documents are to be 0.75 at least. Consequently, the author-assigned keywords proved to be very effective to the document indexing. (auth.)

Automated sequence-specific protein NMR assignment using the memetic algorithm MATCH

International Nuclear Information System (INIS)

Volk, Jochen; Herrmann, Torsten; Wuethrich, Kurt

2008-01-01

MATCH (Memetic Algorithm and Combinatorial Optimization Heuristics) is a new memetic algorithm for automated sequence-specific polypeptide backbone NMR assignment of proteins. MATCH employs local optimization for tracing partial sequence-specific assignments within a global, population-based search environment, where the simultaneous application of local and global optimization heuristics guarantees high efficiency and robustness. MATCH thus makes combined use of the two predominant concepts in use for automated NMR assignment of proteins. Dynamic transition and inherent mutation are new techniques that enable automatic adaptation to variable quality of the experimental input data. The concept of dynamic transition is incorporated in all major building blocks of the algorithm, where it enables switching between local and global optimization heuristics at any time during the assignment process. Inherent mutation restricts the intrinsically required randomness of the evolutionary algorithm to those regions of the conformation space that are compatible with the experimental input data. Using intact and artificially deteriorated APSY-NMR input data of proteins, MATCH performed sequence-specific resonance assignment with high efficiency and robustness

A code reviewer assignment model incorporating the competence differences and participant preferences

Directory of Open Access Journals (Sweden)

Wang Yanqing

2016-03-01

Full Text Available A good assignment of code reviewers can effectively utilize the intellectual resources, assure code quality and improve programmers’ skills in software development. However, little research on reviewer assignment of code review has been found. In this study, a code reviewer assignment model is created based on participants’ preference to reviewing assignment. With a constraint of the smallest size of a review group, the model is optimized to maximize review outcomes and avoid the negative impact of “mutual admiration society”. This study shows that the reviewer assignment strategies incorporating either the reviewers’ preferences or the authors’ preferences get much improvement than a random assignment. The strategy incorporating authors’ preference makes higher improvement than that incorporating reviewers’ preference. However, when the reviewers’ and authors’ preference matrixes are merged, the improvement becomes moderate. The study indicates that the majority of the participants have a strong wish to work with reviewers and authors having highest competence. If we want to satisfy the preference of both reviewers and authors at the same time, the overall improvement of learning outcomes may be not the best.

Organic Chemistry YouTube Writing Assignment for Large Lecture Classes

Science.gov (United States)

Franz, Annaliese K.

2012-01-01

This work describes efforts to incorporate and evaluate the use of a YouTube writing assignment in large lecture classes to personalize learning and improve conceptual understanding of chemistry through peer- and self-explanation strategies. Although writing assignments can be a method to incorporate peer- and self-explanation strategies, this…

Negotiating Languages and Cultures: Enacting Translingualism through a Translation Assignment

Science.gov (United States)

Kiernan, Julia; Meier, Joyce; Wang, Xiqiao

2016-01-01

This collaborative project explores the affordances of a translation assignment in the context of a learner-centered pedagogy that places composition students' movement among languages and cultures as both a site for inquiry and subject of analysis. The translation assignment asks students to translate scholarly articles or culture stories from…

Students' Evaluation of Writing Assignments in an Abnormal Psychology Course.

Science.gov (United States)

Procidano, Mary E.

1991-01-01

Presents a study in which students in an abnormal psychology class rated the usefulness of drafts for two writing assignments. Reports that a research proposal was more effective than a case study in generating interest in psychology and opportunity for creativity. Concludes that writing assignments should reflect important aspects of a…

Bacteria as bullies: effects of linguistic agency assignment in health message.

Science.gov (United States)

Bell, Robert A; McGlone, Matthew S; Dragojevic, Marko

2014-01-01

When describing health threats, communicators can assign agency to the threat (e.g., "Hepatitis C has infected 4 million Americans") or to humans (e.g., "Four million Americans have contracted hepatitis C"). In an online experiment, the authors explored how assignment of agency affects perceptions of susceptibility and severity of a health threat, response efficacy, self-efficacy, fear arousal, and intentions to adopt health-protective recommendations. Participants were 719 individuals recruited through Mechanical Turk ( www.mturk.com ), a crowdsource labor market run by Amazon ( www.amazon.com ). The participants were assigned randomly to read 1 of 8 flyers defined by a 2×4 (Agency Assignment×Topic) factorial design. Each flyer examined 1 health threat (E. coli, necrotizing fasciitis, salmonella, or Carbapenem-resistant Klebsiella pneumoniae) and was written in language that emphasized bacterial or human agency. Perceived susceptibility and severity were highest when bacterial agency language was used. Response efficacy, self-efficacy, and fear arousal were not significantly affected by agency assignment. Participants reported stronger intentions to adopt recommendations when bacteria agency language was used, but this effect did not reach conventional standards of significance (p < .051). The authors concluded that health communicators can increase target audiences' perceptions of susceptibility and severity by assigning agency to the threat in question when devising health messages.

A Stone Resource Assignment Model under the Fuzzy Environment

Directory of Open Access Journals (Sweden)

Liming Yao

2012-01-01

to tackle a stone resource assignment problem with the aim of decreasing dust and waste water emissions. On the upper level, the local government wants to assign a reasonable exploitation amount to each stone plant so as to minimize total emissions and maximize employment and economic profit. On the lower level, stone plants must reasonably assign stone resources to produce different stone products under the exploitation constraint. To deal with inherent uncertainties, the object functions and constraints are defuzzified using a possibility measure. A fuzzy simulation-based improved simulated annealing algorithm (FS-ISA is designed to search for the Pareto optimal solutions. Finally, a case study is presented to demonstrate the practicality and efficiency of the model. Results and a comparison analysis are presented to highlight the performance of the optimization method, which proves to be very efficient compared with other algorithms.

Accurate continuous geographic assignment from low- to high-density SNP data

DEFF Research Database (Denmark)

Guillot, Gilles; Jónsson, Hákon; Hinge, Antoine

2016-01-01

of georeferenced genotypes. Statistical inference under this model can be implemented within the theoretical framework of Integrated Nested Laplace Approximation (INLA), which represents one of the major recent breakthroughs in statistics, devoid of Monte Carlo simulations. We compare the performance of our method...... and SPA in a simulation framework. We highlight the accuracy and limits of continuous spatial assignment methods at various scales by analyzing genotype datasets from a diversity of species, including Florida scrub jay birds Aphelocoma coerulescens, Arabidopsis thaliana and humans, representing 41 to 197...

Wildlife forensic science: A review of genetic geographic origin assignment.

Science.gov (United States)

Ogden, Rob; Linacre, Adrian

2015-09-01

Wildlife forensic science has become a key means of enforcing legislation surrounding the illegal trade in protected and endangered species. A relatively new dimension to this area of forensic science is to determine the geographic origin of a seized sample. This review focuses on DNA testing, which relies on assignment of an unknown sample to its genetic population of origin. Key examples of this are the trade in timber, fish and ivory and these are used only to illustrate the large number of species for which this type of testing is potentially available. The role of mitochondrial and nuclear DNA markers is discussed, alongside a comparison of neutral markers with those exhibiting signatures of selection, which potentially offer much higher levels of assignment power to address specific questions. A review of assignment tests is presented along with detailed methods for evaluating error rates and considerations for marker selection. The availability and quality of reference data are of paramount importance to support assignment applications and ensure reliability of any conclusions drawn. The genetic methods discussed have been developed initially as investigative tools but comment is made regarding their use in courts. The potential to compliment DNA markers with elemental assays for greater assignment power is considered and finally recommendations are made for the future of this type of testing. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Teaching Complaint and Adjustment Letters--And Tact (My Favorite Assignment).

Science.gov (United States)

Deimling, Paula

1992-01-01

Describes a three-part assignment in which each student writes a complaint letter and an adjustment letter responding to another student's complaint letter. Discusses how the third part of the assignment--journal entries--allows students to formulate their own criteria for excellent letters based upon their reactions to the letters they receive.…

On the Use of Writing Assignments in Intermediate Microeconomic Theory

Science.gov (United States)

O'Neill, Patrick B.

2009-01-01

A typical writing assignment in upper level required courses is a term paper. However many economics majors, particularly those in business schools, need to develop skill at writing shorter pieces. In this paper I describe numerous examples of shorter writing assignments that I have incorporated into an Intermediate Microeconomic Theory course.…

Probabilistic validation of protein NMR chemical shift assignments

International Nuclear Information System (INIS)

Dashti, Hesam; Tonelli, Marco; Lee, Woonghee; Westler, William M.; Cornilescu, Gabriel; Ulrich, Eldon L.; Markley, John L.

2016-01-01

Data validation plays an important role in ensuring the reliability and reproducibility of studies. NMR investigations of the functional properties, dynamics, chemical kinetics, and structures of proteins depend critically on the correctness of chemical shift assignments. We present a novel probabilistic method named ARECA for validating chemical shift assignments that relies on the nuclear Overhauser effect data. ARECA has been evaluated through its application to 26 case studies and has been shown to be complementary to, and usually more reliable than, approaches based on chemical shift databases. ARECA is available online at http://areca.nmrfam.wisc.edu/ http://areca.nmrfam.wisc.edu/

Probabilistic validation of protein NMR chemical shift assignments

Energy Technology Data Exchange (ETDEWEB)

Dashti, Hesam [University of Wisconsin-Madison, Graduate Program in Biophysics, Biochemistry Department (United States); Tonelli, Marco; Lee, Woonghee; Westler, William M.; Cornilescu, Gabriel [University of Wisconsin-Madison, Biochemistry Department, National Magnetic Resonance Facility at Madison (United States); Ulrich, Eldon L. [University of Wisconsin-Madison, BioMagResBank, Biochemistry Department (United States); Markley, John L., E-mail: markley@nmrfam.wisc.edu, E-mail: jmarkley@wisc.edu [University of Wisconsin-Madison, Biochemistry Department, National Magnetic Resonance Facility at Madison (United States)

2016-01-15

Data validation plays an important role in ensuring the reliability and reproducibility of studies. NMR investigations of the functional properties, dynamics, chemical kinetics, and structures of proteins depend critically on the correctness of chemical shift assignments. We present a novel probabilistic method named ARECA for validating chemical shift assignments that relies on the nuclear Overhauser effect data. ARECA has been evaluated through its application to 26 case studies and has been shown to be complementary to, and usually more reliable than, approaches based on chemical shift databases. ARECA is available online at http://areca.nmrfam.wisc.edu/ http://areca.nmrfam.wisc.edu/.

Frontier Assignment for Sensitivity Analysis of Data Envelopment Analysis

Science.gov (United States)

Naito, Akio; Aoki, Shingo; Tsuji, Hiroshi

To extend the sensitivity analysis capability for DEA (Data Envelopment Analysis), this paper proposes frontier assignment based DEA (FA-DEA). The basic idea of FA-DEA is to allow a decision maker to decide frontier intentionally while the traditional DEA and Super-DEA decide frontier computationally. The features of FA-DEA are as follows: (1) provides chances to exclude extra-influential DMU (Decision Making Unit) and finds extra-ordinal DMU, and (2) includes the function of the traditional DEA and Super-DEA so that it is able to deal with sensitivity analysis more flexibly. Simple numerical study has shown the effectiveness of the proposed FA-DEA and the difference from the traditional DEA.

Optimal Processor Assignment for Pipeline Computations

Science.gov (United States)

1991-10-01

the use of ratios: initially each task is assigned a procesbuor2 the remaining proceborb are distributed in proportion to the quantities f,(1), 1 < i...algorithmns. IEEE Trans. onl Parallel and Distributed Systemns, 1 (4):470-499, October 1990. [26] P. Al. Kogge. The Architeture of Pipelined Comnputers

7 CFR 1437.104 - Assigned production.

Science.gov (United States)

2010-01-01

...) Irrigation equipment is not capable of supplying adequate water to sustain the expected production of a... practice is not used. (7) For normal irrigated annual and biennial crops, the supply of available water at... determining losses under this section, assigned production will be used to offset the loss of production when...

41 CFR 102-79.20 - What standard must Executive agencies promote when assigning space?

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What standard must Executive agencies promote when assigning space? 102-79.20 Section 102-79.20 Public Contracts and Property... PROPERTY 79-ASSIGNMENT AND UTILIZATION OF SPACE Assignment and Utilization of Space Assignment of Space...

Formularity: Software for Automated Formula Assignment of Natural and Other Organic Matter from Ultrahigh-Resolution Mass Spectra

Energy Technology Data Exchange (ETDEWEB)

Tolic, Nikola; Liu, Yina; Liyu, Andrey V.; Shen, Yufeng; Tfaily, Malak M.; Kujawinski, Elizabeth B.; Longnecker, Krista; Kuo, Li-Jung; Robinson, Errol W.; Pasa Tolic, Ljiljana; Hess, Nancy J.

2017-11-13

Ultrahigh-resolution mass spectrometry, such as Fourier transform ion-cyclotron resonance mass spectrometry (FT-ICR MS), can resolve thousands of molecular ions in complex organic matrices. A Compound Identification Algorithm (CIA) was previously developed for automated elemental formula assignment for natural organic matter (NOM). In this work we describe a user friendly interface for CIA, titled Formularity, which includes an additional functionality to perform search of formulas based on an Isotopic Pattern Algorithm (IPA). While CIA assigns elemental formulas for compounds containing C, H, O, N, S, and P, IPA is capable of assigning formulas for compounds containing other elements. We used halogenated organic compounds (HOC), a chemical class that is ubiquitous in nature as well as anthropogenic systems, as an example to demonstrate the capability of Formularity with IPA. A HOC standard mix was used to evaluate the identification confidence of IPA. The HOC spike in NOM and tap water were used to assess HOC identification in natural and anthropogenic matrices. Strategies for reconciliation of CIA and IPA assignments are discussed. Software and sample databases with documentation are freely available from the PNNL OMICS software repository https://omics.pnl.gov/software/formularity.

A Jigsaw Lesson for Operations of Complex Numbers.

Science.gov (United States)

Lucas, Carol A.

2000-01-01

Explains the cooperative learning technique of jigsaw. Details the use of a jigsaw lesson for explaining complex numbers to intermediate algebra students. Includes copies of the handouts given to the expert groups. (Author/ASK)

Assigning Main Orientation to an EOH Descriptor on Multispectral Images

Directory of Open Access Journals (Sweden)

Yong Li

2015-07-01

Full Text Available This paper proposes an approach to compute an EOH (edge-oriented histogram descriptor with main orientation. EOH has a better matching ability than SIFT (scale-invariant feature transform on multispectral images, but does not assign a main orientation to keypoints. Alternatively, it tends to assign the same main orientation to every keypoint, e.g., zero degrees. This limits EOH to matching keypoints between images of translation misalignment only. Observing this limitation, we propose assigning to keypoints the main orientation that is computed with PIIFD (partial intensity invariant feature descriptor. In the proposed method, SIFT keypoints are detected from images as the extrema of difference of Gaussians, and every keypoint is assigned to the main orientation computed with PIIFD. Then, EOH is computed for every keypoint with respect to its main orientation. In addition, an implementation variant is proposed for fast computation of the EOH descriptor. Experimental results show that the proposed approach performs more robustly than the original EOH on image pairs that have a rotation misalignment.

46 CFR 42.05-10 - Assigning authority.

Science.gov (United States)

2010-10-01

... Definition of Terms Used in This Subchapter § 42.05-10 Assigning authority. This term means the “American Bureau of Shipping” or such other recognized classification society which the Commandant may approve as...

Automation of block assignment planning using a diagram-based scenario modeling method

Directory of Open Access Journals (Sweden)

In Hyuck Hwang

2014-03-01

Full Text Available Most shipbuilding scheduling research so far has focused on the load level on the dock plan. This is because the dock is the least extendable resource in shipyards, and its overloading is difficult to resolve. However, once dock scheduling is completed, making a plan that makes the best use of the rest of the resources in the shipyard to minimize any additional cost is also important. Block assignment planning is one of the midterm planning tasks; it assigns a block to the facility (factory/shop or surface plate that will actually manufacture the block according to the block characteristics and current situation of the facility. It is one of the most heavily loaded midterm planning tasks and is carried out manually by experienced workers. In this study, a method of representing the block assignment rules using a diagram was suggested through analysis of the existing manual process. A block allocation program was developed which automated the block assignment process according to the rules represented by the diagram. The planning scenario was validated through a case study that compared the manual assignment and two automated block assignment results.

Automation of block assignment planning using a diagram-based scenario modeling method

Directory of Open Access Journals (Sweden)

Hwang In Hyuck

2014-03-01

Full Text Available Most shipbuilding scheduling research so far has focused on the load level on the dock plan. This is be¬cause the dock is the least extendable resource in shipyards, and its overloading is difficult to resolve. However, once dock scheduling is completed, making a plan that makes the best use of the rest of the resources in the shipyard to minimize any additional cost is also important. Block assignment planning is one of the midterm planning tasks; it assigns a block to the facility (factory/shop or surface plate that will actually manufacture the block according to the block characteristics and current situation of the facility. It is one of the most heavily loaded midterm planning tasks and is carried out manu¬ally by experienced workers. In this study, a method of representing the block assignment rules using a diagram was su¬ggested through analysis of the existing manual process. A block allocation program was developed which automated the block assignment process according to the rules represented by the diagram. The planning scenario was validated through a case study that compared the manual assignment and two automated block assignment results.

Carbon Monoxide Safety

Science.gov (United States)

... with the Media Fire Protection Technology Carbon monoxide safety outreach materials Keep your community informed about the ... KB | Spanish PDF 592 KB Handout: carbon monoxide safety Download this handout and add your organization's logo ...

A Web Support System for Submission and Handling of Programming Assignments

DEFF Research Database (Denmark)

Nørmark, Kurt

2011-01-01

Individual submission of programming assignments should be considered in all introductory programming courses. We describe a custom web support system for submission and management of programming assignments in an introductory C programming course. Experience from the first time use of the system...... is reported. In addition, we compare the pattern of use with the results of the final exam in order to reveal a possible impact of the programming assignments. We summarize the lessons learned in preparation for improving the system prior to the next round of use in the fall of 2011....

A Complete Parametric Solutions of Eigenstructure Assignment by State-Derivative Feedback for Linear Control Systems

Directory of Open Access Journals (Sweden)

T. H. S. Abdelaziz

2005-01-01

Full Text Available In this paper we introduce a complete parametric approach for solving the problem of eigenstructure assignment via state-derivative feedback for linear systems. This problem is always solvable for any controllable systems iff the open-loop system matrix is nonsingular. In this work, two parametric solutions to the feedback gain matrix are introduced that describe the available degrees of freedom offered by the state-derivative feedback in selecting the associated eigenvectors from an admissible class. These freedoms can be utilized to improve robustness of the closed-loop system. Accordingly, the sensitivity of the assigned eigenvalues to perturbations in the system and gain matrix is minimized. Numerical examples are included to show the effectiveness of the proposed approach. 

Assigned experts with competitive goals withhold information in group decision making

NARCIS (Netherlands)

Toma, C.; Vasiljevic, D.; Oberlé, D.; Butera, F.

2013-01-01

Expertise assignment has been proposed to improve unshared information pooling in group decision making. The current research revises this view by hypothesizing that expertise assignment is beneficial when group members have cooperative goals, but is detrimental when group members have competitive

Assignment methodology for larger RNA oligonucleotides: Application to an ATP-binding RNA aptamer

International Nuclear Information System (INIS)

Dieckmann, Thorsten; Feigon, Juli

1997-01-01

The use of uniform 13C, 15N labeling in the NMR spectroscopic study of RNA structures has greatly facilitated the assignment process in small RNA oligonucleotides. For ribose spinsystem assignments, exploitation of these labels has followed previously developed methods for the study of proteins. However, for sequential assignment of the exchangeable and nonexchangeable protons of the nucleotides, it has been necessary to develop a variety of new NMR experiments. Even these are of limited utility in the unambiguous assignment of larger RNAs due to the short carbon relaxation times and extensive spectral overlap for all nuclei.These problems can largely be overcome by the additional use of base-type selectively 13C, 15N-labeled RNA in combination with a judicious use of related RNAs with base substitutions. We report the application of this approach to a 36-nucleotide ATP-binding RNA aptamer in complex with AMP. Complete sequential 1H assignments, as well as the majority of 13C and 15N assignments, were obtained

AUTOBA: automation of backbone assignment from HN(C)N suite of experiments.

Science.gov (United States)

Borkar, Aditi; Kumar, Dinesh; Hosur, Ramakrishna V

2011-07-01

Development of efficient strategies and automation represent important milestones of progress in rapid structure determination efforts in proteomics research. In this context, we present here an efficient algorithm named as AUTOBA (Automatic Backbone Assignment) designed to automate the assignment protocol based on HN(C)N suite of experiments. Depending upon the spectral dispersion, the user can record 2D or 3D versions of the experiments for assignment. The algorithm uses as inputs: (i) protein primary sequence and (ii) peak-lists from user defined HN(C)N suite of experiments. In the end, one gets H(N), (15)N, C(α) and C' assignments (in common BMRB format) for the individual residues along the polypeptide chain. The success of the algorithm has been demonstrated, not only with experimental spectra recorded on two small globular proteins: ubiquitin (76 aa) and M-crystallin (85 aa), but also with simulated spectra of 27 other proteins using assignment data from the BMRB.

Epidemiological tracking and population assignment of the non-clonal bacterium, Burkholderia pseudomallei.

Science.gov (United States)

Dale, Julia; Price, Erin P; Hornstra, Heidie; Busch, Joseph D; Mayo, Mark; Godoy, Daniel; Wuthiekanun, Vanaporn; Baker, Anthony; Foster, Jeffrey T; Wagner, David M; Tuanyok, Apichai; Warner, Jeffrey; Spratt, Brian G; Peacock, Sharon J; Currie, Bart J; Keim, Paul; Pearson, Talima

2011-12-01

Rapid assignment of bacterial pathogens into predefined populations is an important first step for epidemiological tracking. For clonal species, a single allele can theoretically define a population. For non-clonal species such as Burkholderia pseudomallei, however, shared allelic states between distantly related isolates make it more difficult to identify population defining characteristics. Two distinct B. pseudomallei populations have been previously identified using multilocus sequence typing (MLST). These populations correlate with the major foci of endemicity (Australia and Southeast Asia). Here, we use multiple Bayesian approaches to evaluate the compositional robustness of these populations, and provide assignment results for MLST sequence types (STs). Our goal was to provide a reference for assigning STs to an established population without the need for further computational analyses. We also provide allele frequency results for each population to enable estimation of population assignment even when novel STs are discovered. The ability for humans and potentially contaminated goods to move rapidly across the globe complicates the task of identifying the source of an infection or outbreak. Population genetic dynamics of B. pseudomallei are particularly complicated relative to other bacterial pathogens, but the work here provides the ability for broad scale population assignment. As there is currently no independent empirical measure of successful population assignment, we provide comprehensive analytical details of our comparisons to enable the reader to evaluate the robustness of population designations and assignments as they pertain to individual research questions. Finer scale subdivision and verification of current population compositions will likely be possible with genotyping data that more comprehensively samples the genome. The approach used here may be valuable for other non-clonal pathogens that lack simple group-defining genetic characteristics

Epidemiological tracking and population assignment of the non-clonal bacterium, Burkholderia pseudomallei.

Directory of Open Access Journals (Sweden)

Julia Dale

2011-12-01

Full Text Available Rapid assignment of bacterial pathogens into predefined populations is an important first step for epidemiological tracking. For clonal species, a single allele can theoretically define a population. For non-clonal species such as Burkholderia pseudomallei, however, shared allelic states between distantly related isolates make it more difficult to identify population defining characteristics. Two distinct B. pseudomallei populations have been previously identified using multilocus sequence typing (MLST. These populations correlate with the major foci of endemicity (Australia and Southeast Asia. Here, we use multiple Bayesian approaches to evaluate the compositional robustness of these populations, and provide assignment results for MLST sequence types (STs. Our goal was to provide a reference for assigning STs to an established population without the need for further computational analyses. We also provide allele frequency results for each population to enable estimation of population assignment even when novel STs are discovered. The ability for humans and potentially contaminated goods to move rapidly across the globe complicates the task of identifying the source of an infection or outbreak. Population genetic dynamics of B. pseudomallei are particularly complicated relative to other bacterial pathogens, but the work here provides the ability for broad scale population assignment. As there is currently no independent empirical measure of successful population assignment, we provide comprehensive analytical details of our comparisons to enable the reader to evaluate the robustness of population designations and assignments as they pertain to individual research questions. Finer scale subdivision and verification of current population compositions will likely be possible with genotyping data that more comprehensively samples the genome. The approach used here may be valuable for other non-clonal pathogens that lack simple group-defining genetic

Practical aspects of NMR signal assignment in larger and challenging proteins

Science.gov (United States)

Frueh, Dominique P.

2014-01-01

NMR has matured into a technique routinely employed for studying proteins in near physiological conditions. However, applications to larger proteins are impeded by the complexity of the various correlation maps necessary to assign NMR signals. This article reviews the data analysis techniques traditionally employed for resonance assignment and describes alternative protocols necessary for overcoming challenges in large protein spectra. In particular, simultaneous analysis of multiple spectra may help overcome ambiguities or may reveal correlations in an indirect manner. Similarly, visualization of orthogonal planes in a multidimensional spectrum can provide alternative assignment procedures. We describe examples of such strategies for assignment of backbone, methyl, and nOe resonances. We describe experimental aspects of data acquisition for the related experiments and provide guidelines for preliminary studies. Focus is placed on large folded monomeric proteins and examples are provided for 37, 48, 53, and 81 kDa proteins. PMID:24534088

Applications of random forest feature selection for fine-scale genetic population assignment.

Science.gov (United States)

Sylvester, Emma V A; Bentzen, Paul; Bradbury, Ian R; Clément, Marie; Pearce, Jon; Horne, John; Beiko, Robert G

2018-02-01

Genetic population assignment used to inform wildlife management and conservation efforts requires panels of highly informative genetic markers and sensitive assignment tests. We explored the utility of machine-learning algorithms (random forest, regularized random forest and guided regularized random forest) compared with F ST ranking for selection of single nucleotide polymorphisms (SNP) for fine-scale population assignment. We applied these methods to an unpublished SNP data set for Atlantic salmon ( Salmo salar ) and a published SNP data set for Alaskan Chinook salmon ( Oncorhynchus tshawytscha ). In each species, we identified the minimum panel size required to obtain a self-assignment accuracy of at least 90% using each method to create panels of 50-700 markers Panels of SNPs identified using random forest-based methods performed up to 7.8 and 11.2 percentage points better than F ST -selected panels of similar size for the Atlantic salmon and Chinook salmon data, respectively. Self-assignment accuracy ≥90% was obtained with panels of 670 and 384 SNPs for each data set, respectively, a level of accuracy never reached for these species using F ST -selected panels. Our results demonstrate a role for machine-learning approaches in marker selection across large genomic data sets to improve assignment for management and conservation of exploited populations.

A high throughput single nucleotide polymorphism multiplex assay for parentage assignment in New Zealand sheep.

Directory of Open Access Journals (Sweden)

Shannon M Clarke

Full Text Available Accurate pedigree information is critical to animal breeding systems to ensure the highest rate of genetic gain and management of inbreeding. The abundance of available genomic data, together with development of high throughput genotyping platforms, means that single nucleotide polymorphisms (SNPs are now the DNA marker of choice for genomic selection studies. Furthermore the superior qualities of SNPs compared to microsatellite markers allows for standardization between laboratories; a property that is crucial for developing an international set of markers for traceability studies. The objective of this study was to develop a high throughput SNP assay for use in the New Zealand sheep industry that gives accurate pedigree assignment and will allow a reduction in breeder input over lambing. This required two phases of development--firstly, a method of extracting quality DNA from ear-punch tissue performed in a high throughput cost efficient manner and secondly a SNP assay that has the ability to assign paternity to progeny resulting from mob mating. A likelihood based approach to infer paternity was used where sires with the highest LOD score (log of the ratio of the likelihood given parentage to likelihood given non-parentage are assigned. An 84 "parentage SNP panel" was developed that assigned, on average, 99% of progeny to a sire in a problem where there were 3,000 progeny from 120 mob mated sires that included numerous half sib sires. In only 6% of those cases was there another sire with at least a 0.02 probability of paternity. Furthermore dam information (either recorded, or by genotyping possible dams was absent, highlighting the SNP test's suitability for paternity testing. Utilization of this parentage SNP assay will allow implementation of progeny testing into large commercial farms where the improved accuracy of sire assignment and genetic evaluations will increase genetic gain in the sheep industry.

Comparing cluster-level dynamic treatment regimens using sequential, multiple assignment, randomized trials: Regression estimation and sample size considerations.

Science.gov (United States)

NeCamp, Timothy; Kilbourne, Amy; Almirall, Daniel

2017-08-01

Cluster-level dynamic treatment regimens can be used to guide sequential treatment decision-making at the cluster level in order to improve outcomes at the individual or patient-level. In a cluster-level dynamic treatment regimen, the treatment is potentially adapted and re-adapted over time based on changes in the cluster that could be impacted by prior intervention, including aggregate measures of the individuals or patients that compose it. Cluster-randomized sequential multiple assignment randomized trials can be used to answer multiple open questions preventing scientists from developing high-quality cluster-level dynamic treatment regimens. In a cluster-randomized sequential multiple assignment randomized trial, sequential randomizations occur at the cluster level and outcomes are observed at the individual level. This manuscript makes two contributions to the design and analysis of cluster-randomized sequential multiple assignment randomized trials. First, a weighted least squares regression approach is proposed for comparing the mean of a patient-level outcome between the cluster-level dynamic treatment regimens embedded in a sequential multiple assignment randomized trial. The regression approach facilitates the use of baseline covariates which is often critical in the analysis of cluster-level trials. Second, sample size calculators are derived for two common cluster-randomized sequential multiple assignment randomized trial designs for use when the primary aim is a between-dynamic treatment regimen comparison of the mean of a continuous patient-level outcome. The methods are motivated by the Adaptive Implementation of Effective Programs Trial which is, to our knowledge, the first-ever cluster-randomized sequential multiple assignment randomized trial in psychiatry.

MetaboID: a graphical user interface package for assignment of 1H NMR spectra of bodyfluids and tissues.

Science.gov (United States)

MacKinnon, Neil; Somashekar, Bagganahalli S; Tripathi, Pratima; Ge, Wencheng; Rajendiran, Thekkelnaycke M; Chinnaiyan, Arul M; Ramamoorthy, Ayyalusamy

2013-01-01

Nuclear magnetic resonance based measurements of small molecule mixtures continues to be confronted with the challenge of spectral assignment. While multi-dimensional experiments are capable of addressing this challenge, the imposed time constraint becomes prohibitive, particularly with the large sample sets commonly encountered in metabolomic studies. Thus, one-dimensional spectral assignment is routinely performed, guided by two-dimensional experiments on a selected sample subset; however, a publicly available graphical interface for aiding in this process is currently unavailable. We have collected spectral information for 360 unique compounds from publicly available databases including chemical shift lists and authentic full resolution spectra, supplemented with spectral information for 25 compounds collected in-house at a proton NMR frequency of 900 MHz. This library serves as the basis for MetaboID, a Matlab-based user interface designed to aid in the one-dimensional spectral assignment process. The tools of MetaboID were built to guide resonance assignment in order of increasing confidence, starting from cursory compound searches based on chemical shift positions to analysis of authentic spike experiments. Together, these tools streamline the often repetitive task of spectral assignment. The overarching goal of the integrated toolbox of MetaboID is to centralize the one dimensional spectral assignment process, from providing access to large chemical shift libraries to providing a straightforward, intuitive means of spectral comparison. Such a toolbox is expected to be attractive to both experienced and new metabolomic researchers as well as general complex mixture analysts. Copyright © 2012 Elsevier Inc. All rights reserved.

10 CFR Appendix A to Part 20 - Assigned Protection Factors for Respirators a

Science.gov (United States)

2010-01-01

... internal dose due to inhalation may, in addition, present external exposure hazards at higher... 10 Energy 1 2010-01-01 2010-01-01 false Assigned Protection Factors for Respirators a A Appendix A..., App. A Appendix A to Part 20—Assigned Protection Factors for Respirators a Operating mode Assigned...

Optimisation of timetable-based, stochastic transit assignment models based on MSA

DEFF Research Database (Denmark)

Nielsen, Otto Anker; Frederiksen, Rasmus Dyhr

2006-01-01

(CRM), such a large-scale transit assignment model was developed and estimated. The Stochastic User Equilibrium problem was solved by the Method of Successive Averages (MSA). However, the model suffered from very large calculation times. The paper focuses on how to optimise transit assignment models...

48 CFR 832.805-70 - Distribution/notification of assignment of claims.

Science.gov (United States)

2010-10-01

... assignment of payments for contracts under which payment for articles and services is certified and approved... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Distribution/notification... DEPARTMENT OF VETERANS AFFAIRS GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Assignment of Claims 832...

The concept of symptomatic epilepsy and the complexities of assigning cause in epilepsy.

Science.gov (United States)

Shorvon, Simon

2014-03-01

The concept of symptomatic epilepsy and the difficulties in assigning cause in epilepsy are described. A historical review is given, emphasizing aspects of the history which are relevant today. The historical review is divided into three approximately semicentenial periods (1860-1910, 1910-1960, 1960-present). A definition of symptomatic epilepsy and this is followed by listing of causes of symptomatic epilepsy. The fact that not all the causes of idiopathic epilepsy are genetic is discussed. A category of provoked epilepsy is proposed. The complexities in assigning cause include the following: the multifactorial nature of epilepsy, the distinction between remote and proximate causes, the role of nongenetic factors in idiopathic epilepsy, the role of investigation in determining the range of causes, the fact that not all symptomatic epilepsy is acquired, the nosological position of provoked epilepsy and the view of epilepsy as a process, and the differentiation of new-onset and established epilepsy. The newly proposed ILAE classification of epilepsy and its changes in terminologies and the difficulties in the concept of acute symptomatic epilepsy are discussed, including the inconsistencies and gray areas and the distinction between idiopathic, symptomatic, and provoked epilepsies. Points to be considered in future work are listed. Copyright © 2013 Elsevier Inc. All rights reserved.

Danish Public Construction Counselling Selection and Assignment Criteria in European Tendering

DEFF Research Database (Denmark)

Larsen, Jesper Kranker; Ussing, Lene Faber; Brunø, Thomas Ditlev

2014-01-01

One of the largest customers in the Danish construction industry is public agencies that own and develop projects. For some of the counselling services, they recur to be put out in European tendering. The aim is to find which selection and assignment criteria are used most in public tendering. How...... projects use selection and assignment criteria for counselling services and finally if there is significant use of selection and assignment methods in public counselling. The method is based on 74 public counselling tenders from the European Tenders Electronic Daily database from January 2010 to March 2013...

Controversies of Sex Re-assignment in Genetic Males with Congenital Inadequacy of the Penis.

Science.gov (United States)

Raveenthiran, Venkatachalam

2017-09-01

Sex assignment in 46XY genetic male children with congenital inadequacy of the penis (CIP) is controversial. Traditionally, children with penile length less than 2 cm at birth are considered unsuitable to be raised as males. They are typically re-assigned to female-sex and feminizing genitoplasty is usually done in infancy. However, the concept of cerebral androgen imprinting has caused paradigm shift in the philosophy of sex re-assignment. Masculinization of the brain, rather than length of the penis, is the modern criterion of sex re-assignment in CIP. This review summarizes the current understanding of the complex issue. In 46XY children with CIP, male-sex assignment appears appropriate in non-hormonal conditions such as idiopathic micropenis, aphallia and exstrophy. Female-sex re-assignment appears acceptable in complete androgen insensitivity (CAIS), while partial androgen insensitivity syndrome (PAIS) patients are highly dissatisfied with the assignment of either sex. Children with 5-alpha reductase deficiency are likely to have spontaneous penile lengthening at puberty. Hence, they are better raised as males. Although female assignment is common in pure gonadal dysgenesis, long-term results are not known to justify the decision.

Handout on Health: Back Pain

Science.gov (United States)

... Manipulation . Professionals use their hands to adjust or massage the spine or nearby tissues. Transcutaneous electrical nerve ... to the bones in the spine or by osteoporosis. Degenerative disk disease , or damage to the spine’s ...

Species delineation using Bayesian model-based assignment tests: a case study using Chinese toad-headed agamas (genus Phrynocephalus

Directory of Open Access Journals (Sweden)

Fu Jinzhong

2010-06-01

Full Text Available Abstract Background Species are fundamental units in biology, yet much debate exists surrounding how we should delineate species in nature. Species discovery now requires the use of separate, corroborating datasets to quantify independently evolving lineages and test species criteria. However, the complexity of the speciation process has ushered in a need to infuse studies with new tools capable of aiding in species delineation. We suggest that model-based assignment tests are one such tool. This method circumvents constraints with traditional population genetic analyses and provides a novel means of describing cryptic and complex diversity in natural systems. Using toad-headed agamas of the Phrynocephalus vlangalii complex as a case study, we apply model-based assignment tests to microsatellite DNA data to test whether P. putjatia, a controversial species that closely resembles P. vlangalii morphologically, represents a valid species. Mitochondrial DNA and geographic data are also included to corroborate the assignment test results. Results Assignment tests revealed two distinct nuclear DNA clusters with 95% (230/243 of the individuals being assigned to one of the clusters with > 90% probability. The nuclear genomes of the two clusters remained distinct in sympatry, particularly at three syntopic sites, suggesting the existence of reproductive isolation between the identified clusters. In addition, a mitochondrial ND2 gene tree revealed two deeply diverged clades, which were largely congruent with the two nuclear DNA clusters, with a few exceptions. Historical mitochondrial introgression events between the two groups might explain the disagreement between the mitochondrial and nuclear DNA data. The nuclear DNA clusters and mitochondrial clades corresponded nicely to the hypothesized distributions of P. vlangalii and P. putjatia. Conclusions These results demonstrate that assignment tests based on microsatellite DNA data can be powerful tools

Videos, Podcasts and Livechats

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Full Text Available ... About Donate Search Search What Is It Definition Pediatric Palliative Care Disease Types FAQ Handout for Patients ... diagnosis or treatment. What Is Palliative Care Definition Pediatric Palliative Care Disease Types FAQ Handout for Patients ...

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Full Text Available ... Pediatric Palliative Care Disease Types FAQ Handout for Patients and Families Is It Right for You How ... cancer story Access the Provider Directory Handout for Patients and Families Is it Right for You? Podcasts ...

Model morphing and sequence assignment after molecular replacement.

Science.gov (United States)

Terwilliger, Thomas C; Read, Randy J; Adams, Paul D; Brunger, Axel T; Afonine, Pavel V; Hung, Li-Wei

2013-11-01

A procedure termed `morphing' for improving a model after it has been placed in the crystallographic cell by molecular replacement has recently been developed. Morphing consists of applying a smooth deformation to a model to make it match an electron-density map more closely. Morphing does not change the identities of the residues in the chain, only their coordinates. Consequently, if the true structure differs from the working model by containing different residues, these differences cannot be corrected by morphing. Here, a procedure that helps to address this limitation is described. The goal of the procedure is to obtain a relatively complete model that has accurate main-chain atomic positions and residues that are correctly assigned to the sequence. Residues in a morphed model that do not match the electron-density map are removed. Each segment of the resulting trimmed morphed model is then assigned to the sequence of the molecule using information about the connectivity of the chains from the working model and from connections that can be identified from the electron-density map. The procedure was tested by application to a recently determined structure at a resolution of 3.2 Å and was found to increase the number of correctly identified residues in this structure from the 88 obtained using phenix.resolve sequence assignment alone (Terwilliger, 2003) to 247 of a possible 359. Additionally, the procedure was tested by application to a series of templates with sequence identities to a target structure ranging between 7 and 36%. The mean fraction of correctly identified residues in these cases was increased from 33% using phenix.resolve sequence assignment to 47% using the current procedure. The procedure is simple to apply and is available in the Phenix software package.

Disentangling Mathematics Target and Access Skills: Implications for Accommodation Assignment Practices

Science.gov (United States)

Ketterlin-Geller, Leanne R.; Jamgochian, Elisa M.; Nelson-Walker, Nancy J.; Geller, Joshua P.

2012-01-01

Appropriate assignment of accommodations is predicated on a clear distinction between target skills and access skills. In this study, we examine the agreement between test developer/researchers' and educators' classification of target and access skills as a possible explanatory mechanism for assigning accommodations. Findings indicate that…

Written Assignments for Abnormal Psychology at Howard Community College, Fall 1988.

Science.gov (United States)

Bell, James

Designed for students enrolled in an Abnormal Psychology course at Howard Community College (Maryland), this booklet explains the requirements for the course's writing assignments, which are designed to teach the skills of comparison and contrast, analysis, critical thinking, and synthesis. Following an overview of class assignments and…

Improving Students’ Learning in Software Engineering Education through Multi-Level Assignments

NARCIS (Netherlands)

Dr. Leo Pruijt; Christian Köppe

2014-01-01

Author supplied: DOI : http://dx.doi.org/10.1145/2691352.2691357 Assignments and exercises are an essential part of software engineering education. It usually requires a variety of these assignments to cover a desired wide range of educational objectives as defined in the revised Bloom's taxonomy.

MSOAR 2.0: Incorporating tandem duplications into ortholog assignment based on genome rearrangement

Directory of Open Access Journals (Sweden)

Zhang Liqing

2010-01-01

, it is actually better than that of InParanoid in the simulation tests. Conclusions Our preliminary experimental results demonstrate that MSOAR 2.0 is a highly accurate tool for one-to-one ortholog assignment between closely related genomes. The software is available to the public for free and included as online supplementary material.

The edge complex: implicit memory for figure assignment in shape perception.

Science.gov (United States)

Peterson, Mary A; Enns, James T

2005-05-01

Viewing a stepped edge is likely to prompt the perceptual assignment of one side of the edge as figure. This study demonstrates that even a single brief glance at a novel edge gives rise to an implicit memory regarding which side was seen as figure; this edge complex enters into the figure assignment process the next time the edge is encountered, both speeding same-different judgments when the figural side is repeated and slowing these judgments when the new figural side is identical to the former ground side (Experiments 1A and 1B). These results were obtained even when the facing direction of the repeated edge was mirror reversed (Experiment 2). This study shows that implicit measures can reveal the effects of past experience on figure assignment, following a single prior exposure to a novel shape, and supports a competitive model of figure assignment in which past experience serves as one of many figural cues.

A Statistical Programme Assignment Model

DEFF Research Database (Denmark)

Rosholm, Michael; Staghøj, Jonas; Svarer, Michael

When treatment effects of active labour market programmes are heterogeneous in an observable way  across the population, the allocation of the unemployed into different programmes becomes a particularly  important issue. In this paper, we present a statistical model designed to improve the present...... duration of unemployment spells may result if a statistical programme assignment model is introduced. We discuss several issues regarding the  plementation of such a system, especially the interplay between the statistical model and  case workers....

Integrated project scheduling and staff assignment with controllable processing times.

Science.gov (United States)

Fernandez-Viagas, Victor; Framinan, Jose M

2014-01-01

This paper addresses a decision problem related to simultaneously scheduling the tasks in a project and assigning the staff to these tasks, taking into account that a task can be performed only by employees with certain skills, and that the length of each task depends on the number of employees assigned. This type of problems usually appears in service companies, where both tasks scheduling and staff assignment are closely related. An integer programming model for the problem is proposed, together with some extensions to cope with different situations. Additionally, the advantages of the controllable processing times approach are compared with the fixed processing times. Due to the complexity of the integrated model, a simple GRASP algorithm is implemented in order to obtain good, approximate solutions in short computation times.

Integrated Project Scheduling and Staff Assignment with Controllable Processing Times

Directory of Open Access Journals (Sweden)

Victor Fernandez-Viagas

2014-01-01

Full Text Available This paper addresses a decision problem related to simultaneously scheduling the tasks in a project and assigning the staff to these tasks, taking into account that a task can be performed only by employees with certain skills, and that the length of each task depends on the number of employees assigned. This type of problems usually appears in service companies, where both tasks scheduling and staff assignment are closely related. An integer programming model for the problem is proposed, together with some extensions to cope with different situations. Additionally, the advantages of the controllable processing times approach are compared with the fixed processing times. Due to the complexity of the integrated model, a simple GRASP algorithm is implemented in order to obtain good, approximate solutions in short computation times.

Diabetes HealthSense: Resources for Living Well

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Videos, Podcasts and Livechats

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The Automatic Sweetheart: An Assignment in a History of Psychology Course

Science.gov (United States)

Sibicky, Mark E.

2007-01-01

This article describes an assignment in a History of Psychology course used to enhance student retention of material and increase student interest and discussion of the long-standing debate between humanistic and mechanistic models in psychology. Adapted from William James's (1955) automatic sweetheart question, the assignment asks students to…

A Case-Study Assignment to Teach Theoretical Perspectives in Abnormal Psychology.

Science.gov (United States)

Perkins, David V.

1991-01-01

Describes an assignment that requires students to organize, prepare, and revise a case study in abnormal behavior. Explains that students employ a single theoretical perspective in preparing a report on a figure from history, literature, the arts, or current events. Discusses the value of the assignment for students. (SG)

Quality Assurance of UMLS Semantic Type Assignments Using SNOMED CT Hierarchies.

Science.gov (United States)

Gu, H; Chen, Y; He, Z; Halper, M; Chen, L

2016-01-01

The Unified Medical Language System (UMLS) is one of the largest biomedical terminological systems, with over 2.5 million concepts in its Metathesaurus repository. The UMLS's Semantic Network (SN) with its collection of 133 high-level semantic types serves as an abstraction layer on top of the Metathesaurus. In particular, the SN elaborates an aspect of the Metathesaurus's concepts via the assignment of one or more types to each concept. Due to the scope and complexity of the Metathesaurus, errors are all but inevitable in this semantic-type assignment process. To develop a semi-automated methodology to help assure the quality of semantic-type assignments within the UMLS. The methodology uses a cross-validation strategy involving SNOMED CT's hierarchies in combination with UMLS semantic types. Semantically uniform, disjoint concept groups are generated programmatically by partitioning the collection of all concepts in the same SNOMED CT hierarchy according to their respective semantic-type assignments in the UMLS. Domain experts are then called upon to review the concepts in any group having a small number of concepts. It is our hypothesis that a semantic-type assignment combination applicable only to a very small number of concepts in a SNOMED CT hierarchy is an indicator of potential problems. The methodology was applied to the UMLS 2013AA release along with the SNOMED CT from January 2013. An overall error rate of 33% was found for concepts proposed by the quality-assurance methodology. Supporting our hypothesis, that number was four times higher than the error rate found in control samples. The results show that the quality-assurance methodology can aid in effective and efficient identification of UMLS semantic-type assignment errors.

ZAP: a distributed channel assignment algorithm for cognitive radio networks

OpenAIRE

Junior , Paulo Roberto ,; Fonseca , Mauro; Munaretto , Anelise; Viana , Aline ,; Ziviani , Artur

2011-01-01

Abstract We propose ZAP, an algorithm for the distributed channel assignment in cognitive radio (CR) networks. CRs are capable of identifying underutilized licensed bands of the spectrum, allowing their reuse by secondary users without interfering with primary users. In this context, efficient channel assignment is challenging as ideally it must be simple, incur acceptable communication overhead, provide timely response, and be adaptive to accommodate frequent changes in the network. Another ...

Diabetes HealthSense: Resources for Living Well

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Relationship Structures and Semantic Type Assignments of the UMLS Enriched Semantic Network

Science.gov (United States)

Zhang, Li; Halper, Michael; Perl, Yehoshua; Geller, James; Cimino, James J.

2005-01-01

Objective: The Enriched Semantic Network (ESN) was introduced as an extension of the Unified Medical Language System (UMLS) Semantic Network (SN). Its multiple subsumption configuration and concomitant multiple inheritance make the ESN's relationship structures and semantic type assignments different from those of the SN. A technique for deriving the relationship structures of the ESN's semantic types and an automated technique for deriving the ESN's semantic type assignments from those of the SN are presented. Design: The technique to derive the ESN's relationship structures finds all newly inherited relationships in the ESN. All such relationships are audited for semantic validity, and the blocking mechanism is used to block invalid relationships. The mapping technique to derive the ESN's semantic type assignments uses current SN semantic type assignments and preserves nonredundant categorizations, while preventing new redundant categorizations. Results: Among the 426 newly inherited relationships, 326 are deemed valid. Seven blockings are applied to avoid inheritance of the 100 invalid relationships. Sixteen semantic types have different relationship structures in the ESN as compared to those in the SN. The mapping of semantic type assignments from the SN to the ESN avoids the generation of 26,950 redundant categorizations. The resulting ESN contains 138 semantic types, 149 IS-A links, 7,303 relationships, and 1,013,876 semantic type assignments. Conclusion: The ESN's multiple inheritance provides more complete relationship structures than in the SN. The ESN's semantic type assignments avoid the existing redundant categorizations appearing in the SN and prevent new ones that might arise due to multiple parents. Compared to the SN, the ESN provides a more accurate unifying semantic abstraction of the UMLS Metathesaurus. PMID:16049233

Auditing the Assignments of Top-Level Semantic Types in the UMLS Semantic Network to UMLS Concepts.

Science.gov (United States)

He, Zhe; Perl, Yehoshua; Elhanan, Gai; Chen, Yan; Geller, James; Bian, Jiang

2017-11-01

The Unified Medical Language System (UMLS) is an important terminological system. By the policy of its curators, each concept of the UMLS should be assigned the most specific Semantic Types (STs) in the UMLS Semantic Network (SN). Hence, the Semantic Types of most UMLS concepts are assigned at or near the bottom (leaves) of the UMLS Semantic Network. While most ST assignments are correct, some errors do occur. Therefore, Quality Assurance efforts of UMLS curators for ST assignments should concentrate on automatically detected sets of UMLS concepts with higher error rates than random sets. In this paper, we investigate the assignments of top-level semantic types in the UMLS semantic network to concepts, identify potential erroneous assignments, define four categories of errors, and thus provide assistance to curators of the UMLS to avoid these assignments errors. Human experts analyzed samples of concepts assigned 10 of the top-level semantic types and categorized the erroneous ST assignments into these four logical categories. Two thirds of the concepts assigned these 10 top-level semantic types are erroneous. Our results demonstrate that reviewing top-level semantic type assignments to concepts provides an effective way for UMLS quality assurance, comparing to reviewing a random selection of semantic type assignments.

OSHA. Training Module 4.330.3.77.

Science.gov (United States)

Fillenwarth, Lynn; Bonnstetter, Ron

This document is an instructional module package prepared in objective form for use by an instructor familiar with the Federal and Iowa Occupational Safety and Health Act (OSHA). Included are objectives, instructor guides, and student handouts. This module includes an overview of OSHA administration, analysis of OSHA standards including…

My Favorite Assignment: From the ABC 2010 Annual Convention, Chicago, Illinois

Science.gov (United States)

Whalen, D. Joel

2011-01-01

The seven Favorite Assignments featured in this article were originally presented at the 2010 ABC Annual Convention, Chicago, Illinois. The reader can consider a variety of learning objectives from team building to persuasion, application of electronic media to face-to-face communication, and much more. Some Favorite Assignments take a full…

20 CFR 658.411 - Filing and assignment of JS-related complaints.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Filing and assignment of JS-related... Agency Js Complaint System § 658.411 Filing and assignment of JS-related complaints. (a) JS-related... office personnel shall be as follows: (1) All JS-related complaints filed with a local office, and...

42 CFR 424.73 - Prohibition of assignment of claims by providers.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Prohibition of assignment of claims by providers. 424.73 Section 424.73 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND... and Reassignment of Claims § 424.73 Prohibition of assignment of claims by providers. (a) Basic...

76 FR 42706 - Amendment of Inspector General Operations & Reporting System Audit, Assignment, and Timesheet...

Science.gov (United States)

2011-07-19

... Operations & Reporting System Audit, Assignment, and Timesheet Files (EPA-42) AGENCY: Environmental... (IGOR) System Audit, Assignment, and Timesheet Files (EPA-42) to the Inspector General Enterprise Management System (IGEMS) Audit, Assignment, and Timesheet Modules. DATES: Effective Dates: Persons wishing...

Teaching Hiroshima: Thinking about the Unthinkable.

Science.gov (United States)

Dyke, Reg

1983-01-01

Describes the instructional materials used in a sophomore literature course to deal with the topic of possible nuclear destruction, including John Hersey's "Hiroshima"; photographs of Hiroshima and Nagasaki; Carl Sagan's "Cosmos"; and specially prepared handouts and worksheets. (LAL)

Concurrent Mass Measurement and Laser Spectroscopy for Unambiguous Isomeric State Assignment

Science.gov (United States)

Lascar, Daniel; Babcock, Carla; Henderson, Jack; Pearson, Matt

2017-09-01

Recent work by the TITAN group at TRIUMF on isomeric state mass measurements of odd-A, neutron-rich cadmium nuclei has shown a disconnect between experiment and theory in 127 g , mCd. The spin and parity assignments of the ground and isomeric states are assigned as 3/2+ and 11/2-, respectively, primarily via systematic arguments. Conversely, state of the art shell model and ab initio calculations show a reversal of the states, predicting a ground state of 11/2- and a 3/2+ isomer. Penning Trap Mass Spectrometry (PTMS) can measure the energy separation between the ground state and the isomer without ambiguity but cannot, on its own, comment on the spin and parity. Collinear Laser Spectroscopy (CLS) experiments have been performed on 127Cd and have elegantly demonstrated the existence of both 3/2+ and 11/2- states. What CLS cannot do, on its own, is assign an ordering to those states. If, however, a PTMS and CLS experiment could be performed concurrently using identical beams from the same facility then there exists sufficient information shared between both experiments that a definitive assignment can be made. We present a concept for a new slate of measurements using existing experimental facilities simultaneously, with shared resources, to definitively assign spin and parity for ground and isomeric states in short-lived nuclei.

Incentivized optimal advert assignment via utility decomposition

NARCIS (Netherlands)

Kelly, F.; Key, P.; Walton, N.

2014-01-01

We consider a large-scale Ad-auction where adverts are assigned over a potentially infinite number of searches. We capture the intrinsic asymmetries in information between advertisers, the advert platform and the space of searches: advertisers know and can optimize the average performance of their

9 CFR 355.10 - Assignment of inspectors.

Science.gov (United States)

2010-01-01

... INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Assignment of inspectors. 355.10 Section 355.10 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE...

A game theoretic approach to assignment problems

NARCIS (Netherlands)

Klijn, F.

2000-01-01

Game theory deals with the mathematical modeling and analysis of conflict and cooperation in the interaction of multiple decision makers. This thesis adopts two game theoretic methods to analyze a range of assignment problems that arise in various economic situations. The first method has as

Assignments of rights and obligations under a gas sales contract

International Nuclear Information System (INIS)

Kowch, J.R.M.

1996-01-01

A general overview of the principles of assignment in a gas sales contract was presented. Assignment is a process wherein the rights or obligations under a contract are transferred from one of the contracting parties to a third party. It is, in other words, the introduction of a new party to the original contractual relationship. Under the rights and obligations of a gas sales contract, the most important right of the seller is to have its gas taken and to be paid. Likewise, the most important obligation of the buyer is to take the gas and pay for it. An assignment by either party has the potential to alter the original expectations of the parties or the basis of which they committed to the contract in the first place. Prior to deregulation and unbundling initiatives, gas sellers and buyers could enter a 20 year sales contract and deal exclusively with each other over the entire 20 year term. Since deregulation, there are more players, and a higher level of corporate acquisitions, divestitures, rationalizations, and restructuring. Today, there are greater chances than ever before that the original party to a contract may change, or that certain rights and obligations may be assigned to a third party and affect the expectations under the contract

A career exploration assignment for first-year pharmacy students.

Science.gov (United States)

Sholy, Lydia; Zeenny, Rony

2013-11-12

To develop, implement, and assess student-learning outcomes from an assignment designed to expose first-year pharmacy students (P1) to a wide range of pharmacy career pathways. Students enrolled in a required Pharmacy Practice and Ethics course at the Lebanese American University chose 1 pharmacist career to investigate from a suggested list of 28 career pathways. Students completed a literature review on the selected career, interviewed a pharmacist practicing that career path in Lebanon, wrote a paper, and prepared and delivered a summary presentation to their classmates about the career pathway. Students peer evaluated their classmates after each presentation. More than 85% of the students scored ≥70% on the assignment based on their achievement of student learning outcomes. Responses on an anonymous questionnaire showed that more than 94.6% of students were satisfied with the extent to which the course allowed them to meet the established learning outcomes. A career exploration assignment provided pharmacy students with an opportunity to widen their knowledge and understanding of the different career pathways that are available for them.

Diabetes HealthSense: Resources for Living Well

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Full Text Available ... right track. Cope with Stress and Emotions AADE7 Self-Care Behaviors Handouts - Healthy Coping These handouts provide facts, ... advice, and activities for seven different areas of self-care to focus on when you are trying to ...

Integrating Graphing Assignments into a Money and Banking Course Using FRED

Science.gov (United States)

Staveley-O'Carroll, James

2018-01-01

Over the course of one semester, six empirical assignments that utilize FRED are used to introduce students of money and banking courses to the economic analysis required for the conduct of monetary policy. The first five assignments cover the following topics: inflation, bonds and stocks, monetary aggregates, the Taylor rule, and employment.…

A demand assignment control in international business satellite communications network

Science.gov (United States)

Nohara, Mitsuo; Takeuchi, Yoshio; Takahata, Fumio; Hirata, Yasuo

An experimental system is being developed for use in an international business satellite (IBS) communications network based on demand-assignment (DA) and TDMA techniques. This paper discusses its system design, in particular from the viewpoints of a network configuration, a DA control, and a satellite channel-assignment algorithm. A satellite channel configuration is also presented along with a tradeoff study on transmission rate, HPA output power, satellite resource efficiency, service quality, and so on.

De novo clustering methods outperform reference-based methods for assigning 16S rRNA gene sequences to operational taxonomic units

Directory of Open Access Journals (Sweden)

Sarah L. Westcott

2015-12-01

Full Text Available Background. 16S rRNA gene sequences are routinely assigned to operational taxonomic units (OTUs that are then used to analyze complex microbial communities. A number of methods have been employed to carry out the assignment of 16S rRNA gene sequences to OTUs leading to confusion over which method is optimal. A recent study suggested that a clustering method should be selected based on its ability to generate stable OTU assignments that do not change as additional sequences are added to the dataset. In contrast, we contend that the quality of the OTU assignments, the ability of the method to properly represent the distances between the sequences, is more important.Methods. Our analysis implemented six de novo clustering algorithms including the single linkage, complete linkage, average linkage, abundance-based greedy clustering, distance-based greedy clustering, and Swarm and the open and closed-reference methods. Using two previously published datasets we used the Matthew’s Correlation Coefficient (MCC to assess the stability and quality of OTU assignments.Results. The stability of OTU assignments did not reflect the quality of the assignments. Depending on the dataset being analyzed, the average linkage and the distance and abundance-based greedy clustering methods generated OTUs that were more likely to represent the actual distances between sequences than the open and closed-reference methods. We also demonstrated that for the greedy algorithms VSEARCH produced assignments that were comparable to those produced by USEARCH making VSEARCH a viable free and open source alternative to USEARCH. Further interrogation of the reference-based methods indicated that when USEARCH or VSEARCH were used to identify the closest reference, the OTU assignments were sensitive to the order of the reference sequences because the reference sequences can be identical over the region being considered. More troubling was the observation that while both USEARCH and

Fluidity models in ancient Greece and current practices of sex assignment.

Science.gov (United States)

Chen, Min-Jye; McCann-Crosby, Bonnie; Gunn, Sheila; Georgiadis, Paraskevi; Placencia, Frank; Mann, David; Axelrad, Marni; Karaviti, L P; McCullough, Laurence B

2017-06-01

Disorders of sexual differentiation such as androgen insensitivity and gonadal dysgenesis can involve an intrinsic fluidity at different levels, from the anatomical and biological to the social (gender) that must be considered in the context of social constraints. Sex assignment models based on George Engel's biopsychosocial aspects model of biology accept fluidity of gender as a central concept and therefore help establish expectations within the uncertainty of sex assignment and anticipate potential changes. The biology underlying the fluidity inherent to these disorders should be presented to parents at diagnosis, an approach that the gender medicine field should embrace as good practice. Greek mythology provides many accepted archetypes of change, and the ancient Greek appreciation of metamorphosis can be used as context with these patients. Our goal is to inform expertise and optimal approaches, knowing that this fluidity may eventually necessitate sex reassignment. Physicians should provide sex assignment education based on different components of sexual differentiation, prepare parents for future hormone-triggered changes in their children, and establish a sex-assignment algorithm. Copyright © 2017 Elsevier Inc. All rights reserved.

Edge-assignment and figure-ground segmentation in short-term visual matching.

Science.gov (United States)

Driver, J; Baylis, G C

1996-12-01

Eight experiments examined the role of edge-assignment in a contour matching task. Subjects judged whether the jagged vertical edge of a probe shape matched the jagged edge that divided two adjoining shapes in an immediately preceding figure-ground display. Segmentation factors biased assignment of this dividing edge toward a figural shape on just one of its sides. Subjects were faster and more accurate at matching when the probe edge had a corresponding assignment. The rapid emergence of this effect provides an on-line analog of the long-term memory advantage for figures over grounds which Rubin (1915/1958) reported. The present on-line advantage was found when figures were defined by relative contrast and size, or by symmetry, and could not be explained solely by the automatic drawing of attention toward the location of the figural region. However, deliberate attention to one region of an otherwise ambiguous figure-ground display did produce the advantage. We propose that one-sided assignment of dividing edges may be obligatory in vision.

Fluidity models in ancient Greece and current practices of sex assignment

Science.gov (United States)

Chen, Min-Jye; McCann-Crosby, Bonnie; Gunn, Sheila; Georgiadis, Paraskevi; Placencia, Frank; Mann, David; Axelrad, Marni; Karaviti, L.P; McCullough, Laurence B.

2018-01-01

Disorders of sexual differentiation such as androgen insensitivity and gonadal dysgenesis can involve an intrinsic fluidity at different levels, from the anatomical and biological to the social (gender) that must be considered in the context of social constraints. Sex assignment models based on George Engel’s biopsychosocial aspects model of biology accept fluidity of gender as a central concept and therefore help establish expectations within the uncertainty of sex assignment and anticipate potential changes. The biology underlying the fluidity inherent to these disorders should be presented to parents at diagnosis, an approach that the gender medicine field should embrace as good practice. Greek mythology provides many accepted archetypes of change, and the ancient Greek appreciation of metamorphosis can be used as context with these patients. Our goal is to inform expertise and optimal approaches, knowing that this fluidity may eventually necessitate sex reassignment. Physicians should provide sex assignment education based on different components of sexual differentiation, prepare parents for future hormone-triggered changes in their children, and establish a sex-assignment algorithm. PMID:28478088

Assignment of stock keeping units to parallel undirectional picking

Directory of Open Access Journals (Sweden)

Matthews, Jason

2015-05-01

Full Text Available An order picking system consisting of a number of parallel unidirectional picking lines is investigated. Stock keeping units (SKUs that are grouped by product type into distributions (DBNs are assigned daily to available picking lines. A mathematical programming formulation and its relaxations is presented. A greedy insertion and a greedy phased insertion are further introduced to obtain feasible results within usable computation times for all test cases. The walking distance of the pickers was shown to decrease by about 22 per cent compared with the current assignment approach. However, product handling and operational risk increases.

Distributed Schemes for Crowdsourcing-Based Sensing Task Assignment in Cognitive Radio Networks

Directory of Open Access Journals (Sweden)

Linbo Zhai

2017-01-01

Full Text Available Spectrum sensing is an important issue in cognitive radio networks. The unlicensed users can access the licensed wireless spectrum only when the licensed wireless spectrum is sensed to be idle. Since mobile terminals such as smartphones and tablets are popular among people, spectrum sensing can be assigned to these mobile intelligent terminals, which is called crowdsourcing method. Based on the crowdsourcing method, this paper studies the distributed scheme to assign spectrum sensing task to mobile terminals such as smartphones and tablets. Considering the fact that mobile terminals’ positions may influence the sensing results, a precise sensing effect function is designed for the crowdsourcing-based sensing task assignment. We aim to maximize the sensing effect function and cast this optimization problem to address crowdsensing task assignment in cognitive radio networks. This problem is difficult to be solved because the complexity of this problem increases exponentially with the growth in mobile terminals. To assign crowdsensing task, we propose four distributed algorithms with different transition probabilities and use a Markov chain to analyze the approximation gap of our proposed schemes. Simulation results evaluate the average performance of our proposed algorithms and validate the algorithm’s convergence.

A New Approach to Weapon-Target Assignment in Cooperative Air Combat

Directory of Open Access Journals (Sweden)

Yi-zhe Chang

2017-01-01

Full Text Available A new approach to solving weapon-target assignment (WTA problem is proposed in this paper. Firstly, relative superiority that lays the foundation for assignment is calculated based on the combat power energy of the fighters. Based on the relative superiority, WTA problem is formulated. Afterwards, a hybrid algorithm consisting of improved artificial fish swarm algorithm (AFSA and improved harmony search (HS is introduced and furthermore applied to solve the assignment formulation. Finally, the proposed approach is validated by eight representative benchmark functions and two concrete cooperative air combat examples. The results show that the approach proposed in this paper achieves good performances in solving WTA problem in cooperative air combat.

Diabetes HealthSense: Resources for Living Well

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Full Text Available ... the resources below to help you get on the right track. Cope with Stress and Emotions AADE7 Self-Care Behaviors Handouts - Healthy Coping These handouts provide ... This booklet addresses the special challenges for very large people who are ...

Empirical Selection of Informative Microsatellite Markers within Co-ancestry Pig Populations Is Required for Improving the Individual Assignment Efficiency

Directory of Open Access Journals (Sweden)

Y. H. Li

2014-05-01

Full Text Available The Lanyu is a miniature pig breed indigenous to Lanyu Island, Taiwan. It is distantly related to Asian and European pig breeds. It has been inbred to generate two breeds and crossed with Landrace and Duroc to produce two hybrids for laboratory use. Selecting sets of informative genetic markers to track the genetic qualities of laboratory animals and stud stock is an important function of genetic databases. For more than two decades, Lanyu derived breeds of common ancestry and crossbreeds have been used to examine the effectiveness of genetic marker selection and optimal approaches for individual assignment. In this paper, these pigs and the following breeds: Berkshire, Duroc, Landrace and Yorkshire, Meishan and Taoyuan, TLRI Black Pig No. 1, and Kaohsiung Animal Propagation Station Black pig are studied to build a genetic reference database. Nineteen microsatellite markers (loci provide information on genetic variation and differentiation among studied breeds. High differentiation index (FST and Cavalli-Sforza chord distances give genetic differentiation among breeds, including Lanyu’s inbred populations. Inbreeding values (FIS show that Lanyu and its derived inbred breeds have significant loss of heterozygosity. Individual assignment testing of 352 animals was done with different numbers of microsatellite markers in this study. The testing assigned 99% of the animals successfully into their correct reference populations based on 9 to 14 markers ranking D-scores, allelic number, expected heterozygosity (HE or FST, respectively. All miss-assigned individuals came from close lineage Lanyu breeds. To improve individual assignment among close lineage breeds, microsatellite markers selected from Lanyu populations with high polymorphic, heterozygosity, FST and D-scores were used. Only 6 to 8 markers ranking HE, FST or allelic number were required to obtain 99% assignment accuracy. This result suggests empirical examination of assignment-error rates

FISCAL DECENTRALIZATION IN THE DRC: EVIDENCE OFREVENUE ASSIGNMENT

Directory of Open Access Journals (Sweden)

Angelita Kithatu-Kiwekete

2017-07-01

Full Text Available The rationalefor central government to devolve resources for service provisionhas been debated in decentralization literature. Decentralization enhancesdemocracy,encouragesparticipation in local development initiativesandpromotes local political accountability.This discourse has been complemented bythe implementation of fiscal decentralization to increase the ability of sub-nationalgovernment in financing municipal service delivery. Fiscal decentralization hasoften been adopted by African statessince the onset ofthe New PublicManagement erain an effortto improvethe standard ofgovernance. The concernis that African states have taken minimal steps to adopt fiscal devolution thatpromotes revenue assignment which in turn limits sub-nationalgovernments’ability to generate own source revenues.This article examines the revenue assignment function of fiscal decentralization inthe Democratic Republic of Congo(DRCinthelight of decentralizationconcerns that have been raised by civil society, as the country charts its course todemocracy. The article is a desktop study that will consider documents andpoliciesin theDRCon thenational, provincialand locallevel as far asstaterevenue sourcesare concerned. Revenue assignment should enable DRC’sprovinces and local authoritiestogeneratesignificantrevenueindependently.However, post-conflict reconstruction and development efforts in the Great Lakesregion and in the DRC have largely isolated decentralization which wouldotherwise entrench local fiscalautonomy infinancing for local services anddevelopment. The article concludes that revenue generation for local authoritiesandtheprovinces in the DRC is still very centralised by the national government.Thearticleproposes policy recommendations that will be useful for the country toensurethatdecentralization effortsinclude fiscal devolution toenhance thefinancing for local development initiatives.

Generalised Assignment Matrix Methodology in Linear Programming

Science.gov (United States)

Jerome, Lawrence

2012-01-01

Discrete Mathematics instructors and students have long been struggling with various labelling and scanning algorithms for solving many important problems. This paper shows how to solve a wide variety of Discrete Mathematics and OR problems using assignment matrices and linear programming, specifically using Excel Solvers although the same…

Conformation of antifreeze glycoproteins as determined from conformational energy calculations and fully assigned proton NMR spectra

International Nuclear Information System (INIS)

Bush, C.A.; Rao, B.N.N.

1986-01-01

The 1 H NMR spectra of AFGP's ranging in molecular weight from 2600 to 30,000 Daltons isolated from several different species of polar fish have been measured. The spectrum of AFGP 1-4 from Pagothenia borchgrevinki with an average of 30 repeating subunits has a single resonance for each proton of the glycotripeptide repeating unit, (ala-[gal-(β-1→3) galNAc-(α--O-]thr-ala)/sub n/. Its 1 H NMR spectrum including resonances of the amide protons has been completely assigned. Coupling constants and nuclear Overhauser enhancements (n.O.e.) between protons on distant residues imply conformational order. The 2600 dalton molecular weight glycopeptides (AFGP-8) have pro in place of ala at certain specific points in the sequence and AFGP-8R of Eleginus gracilis has arg in place of one thr. The resonances of pro and arg were assigned by decoupling. The resonances of the carboxy and amino terminals have distinct chemical shifts and were assigned in AFGP-8 of Boreogadus saida by titration. n.O.e. between α--protons and amide protons of the adjacent residue (sequential n.O.e.) were used in assignments of additional resonances and to assign the distinctive resonances of thr followed by pro. Conformational energy calculations on the repeating glycotripeptide subunit of AFGP show that the α--glucosidic linkage has a fixed conformation while the β--linkage is less rigid. A conformational model for AFGP 1-4, which is based on the calculations has the peptide in an extended left-handed helix with three residues per turn similar to polyproline II. The model is consistent with CD data, amide proton coupling constants, temperature dependence of amide proton chemical shifts

Proposed criteria for the evaluation of an address assignment scheme in Botswana

CSIR Research Space (South Africa)

Ditsela, J

2011-06-01

Full Text Available propose criteria for an address assignment scheme in Botswana: a single set of place or area names; different addresses types for urban, rural and farm areas; principles for address numbering assignment; integration of different referencing systems; and a...

Using the Efficient Frontier to Obtain the Best Solution for the Storage Location Assignment Problem

Directory of Open Access Journals (Sweden)

Marcele Elisa Fontana

2014-01-01

Full Text Available The main variables that influence the efficiency of a warehouse are the use of space and the order picking distance. In the literature, there are proposals to add the costs with space and order picking in order to evaluate each alternative for storage location assignment. However, there were problems with the adoption of this methodology, including difficulties in determining the costs and tradeoffs between them. These difficulties can result in solutions that are suboptimal. Based on these facts, this paper proposes a class-based storage process and storage location assignment by a cube-per-order index (COI that analyzes the space required and the total order picking distance by Pareto-optimal calculations. The efficient frontier possibilities allow the reduction of the set of alternatives, and the DM can analyze only the alternatives on efficient frontier.

Determining the relationship between students' scores using traditional homework assignments to those who used assignments on a non-traditional interactive CD with tutor helps

Science.gov (United States)

Tinney, Charles Evan

2007-12-01

By using the book "Physics for Scientists and Engineers" by Raymond A. Serway as a guide, CD problem sets for teaching a calculus-based physics course were developed, programmed, and evaluated for homework assignments during the 2003-2004 academic year at Utah State University. These CD sets were used to replace the traditionally handwritten and submitted homework sets. They included a research-based format that guided the students through problem-solving techniques using responseactivated helps and suggestions. The CD contents were designed to help the student improve his/her physics problem-solving skills. The analyzed score results showed a direct correlation between the scores obtained on the homework and the students' time spent per problem, as well as the number of helps used per problem.

7 CFR 246.14 - Program costs.

Science.gov (United States)

2010-01-01

... following: (1) The cost of nutrition education and breastfeeding promotion and support which meets the... documentation of the nutrition education and breastfeeding promotion and support expenditure requirement. Costs... producing nutrition education and breastfeeding promotion and support materials including handouts, flip...

MARTA: a suite of Java-based tools for assigning taxonomic status to DNA sequences.

Science.gov (United States)

Horton, Matthew; Bodenhausen, Natacha; Bergelson, Joy

2010-02-15

We have created a suite of Java-based software to better provide taxonomic assignments to DNA sequences. We anticipate that the program will be useful for protistologists, virologists, mycologists and other microbial ecologists. The program relies on NCBI utilities including the BLAST software and Taxonomy database and is easily manipulated at the command-line to specify a BLAST candidate's query-coverage or percent identity requirements; other options include the ability to set minimal consensus requirements (%) for each of the eight major taxonomic ranks (Domain, Kingdom, Phylum, ...) and whether to consider lower scoring candidates when the top-hit lacks taxonomic classification.

A Hybrid Model for Making Online Assignments Effective In a Traditional Classroom

Directory of Open Access Journals (Sweden)

Ronda Sturgill

2011-04-01

Full Text Available Today’s college student has grown up in a world filled with technology and many current college students routinely utilize the latest and most up to date forms of technology. The result is an ever-changing way of communicating between faculty members and students. Many faculty members, however, are intimidated by the use of the terms “technology”, “online” and “distance education.” This often results in a communication gap between faculty and students where faculty members will “lose” students on the first day of class. Advantages of incorporating online tools into the course structure include freeing up additional class time, enhancing classroom discussions, and allowing students to remain current with information in their field. This hybrid instructional model focuses on the integration of technology tools as a supplement to traditional classroom teaching. This paper will describe how to effectively incorporate and implement technology using online course tools in a traditional classroom setting. Specific examples of online assignments, discussions, and assessments from an allied health education program and class will be discussed. Lessons learned and challenges confronted when adapting to the utilization of specific online course assignments and tools will be discussed.

Model morphing and sequence assignment after molecular replacement

Energy Technology Data Exchange (ETDEWEB)

Terwilliger, Thomas C., E-mail: terwilliger@lanl.gov [Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545 (United States); Read, Randy J. [University of Cambridge, Cambridge Institute for Medical Research, Cambridge CB2 0XY (United Kingdom); Adams, Paul D. [Lawrence Berkeley National Laboratory, One Cyclotron Road, Bldg 64R0121, Berkeley, CA 94720 (United States); Brunger, Axel T. [Stanford University, 318 Campus Drive West, Stanford, CA 94305 (United States); Afonine, Pavel V. [Lawrence Berkeley National Laboratory, One Cyclotron Road, Bldg 64R0121, Berkeley, CA 94720 (United States); Hung, Li-Wei [Los Alamos National Laboratory, Mail Stop M888, Los Alamos, NM 87545 (United States)

2013-11-01

A procedure for model building is described that combines morphing a model to match a density map, trimming the morphed model and aligning the model to a sequence. A procedure termed ‘morphing’ for improving a model after it has been placed in the crystallographic cell by molecular replacement has recently been developed. Morphing consists of applying a smooth deformation to a model to make it match an electron-density map more closely. Morphing does not change the identities of the residues in the chain, only their coordinates. Consequently, if the true structure differs from the working model by containing different residues, these differences cannot be corrected by morphing. Here, a procedure that helps to address this limitation is described. The goal of the procedure is to obtain a relatively complete model that has accurate main-chain atomic positions and residues that are correctly assigned to the sequence. Residues in a morphed model that do not match the electron-density map are removed. Each segment of the resulting trimmed morphed model is then assigned to the sequence of the molecule using information about the connectivity of the chains from the working model and from connections that can be identified from the electron-density map. The procedure was tested by application to a recently determined structure at a resolution of 3.2 Å and was found to increase the number of correctly identified residues in this structure from the 88 obtained using phenix.resolve sequence assignment alone (Terwilliger, 2003 ▶) to 247 of a possible 359. Additionally, the procedure was tested by application to a series of templates with sequence identities to a target structure ranging between 7 and 36%. The mean fraction of correctly identified residues in these cases was increased from 33% using phenix.resolve sequence assignment to 47% using the current procedure. The procedure is simple to apply and is available in the Phenix software package.

Model morphing and sequence assignment after molecular replacement

International Nuclear Information System (INIS)

Terwilliger, Thomas C.; Read, Randy J.; Adams, Paul D.; Brunger, Axel T.; Afonine, Pavel V.; Hung, Li-Wei

2013-01-01

A procedure for model building is described that combines morphing a model to match a density map, trimming the morphed model and aligning the model to a sequence. A procedure termed ‘morphing’ for improving a model after it has been placed in the crystallographic cell by molecular replacement has recently been developed. Morphing consists of applying a smooth deformation to a model to make it match an electron-density map more closely. Morphing does not change the identities of the residues in the chain, only their coordinates. Consequently, if the true structure differs from the working model by containing different residues, these differences cannot be corrected by morphing. Here, a procedure that helps to address this limitation is described. The goal of the procedure is to obtain a relatively complete model that has accurate main-chain atomic positions and residues that are correctly assigned to the sequence. Residues in a morphed model that do not match the electron-density map are removed. Each segment of the resulting trimmed morphed model is then assigned to the sequence of the molecule using information about the connectivity of the chains from the working model and from connections that can be identified from the electron-density map. The procedure was tested by application to a recently determined structure at a resolution of 3.2 Å and was found to increase the number of correctly identified residues in this structure from the 88 obtained using phenix.resolve sequence assignment alone (Terwilliger, 2003 ▶) to 247 of a possible 359. Additionally, the procedure was tested by application to a series of templates with sequence identities to a target structure ranging between 7 and 36%. The mean fraction of correctly identified residues in these cases was increased from 33% using phenix.resolve sequence assignment to 47% using the current procedure. The procedure is simple to apply and is available in the Phenix software package

28 CFR 345.35 - Assignments to FPI.

Science.gov (United States)

2010-07-01

..., color, religion, ethnic origin, age, or disability. (b) The SOI ordinarily makes assignments based on... course in pre-industrial training or on-the-job training (as available) before promotion to pay grade four. (2) An inmate who has not successfully completed pre-industrial or on-the-job training remains at...

Fragment assignment in the cloud with eXpress-D

Science.gov (United States)

2013-01-01

Background Probabilistic assignment of ambiguously mapped fragments produced by high-throughput sequencing experiments has been demonstrated to greatly improve accuracy in the analysis of RNA-Seq and ChIP-Seq, and is an essential step in many other sequence census experiments. A maximum likelihood method using the expectation-maximization (EM) algorithm for optimization is commonly used to solve this problem. However, batch EM-based approaches do not scale well with the size of sequencing datasets, which have been increasing dramatically over the past few years. Thus, current approaches to fragment assignment rely on heuristics or approximations for tractability. Results We present an implementation of a distributed EM solution to the fragment assignment problem using Spark, a data analytics framework that can scale by leveraging compute clusters within datacenters–“the cloud”. We demonstrate that our implementation easily scales to billions of sequenced fragments, while providing the exact maximum likelihood assignment of ambiguous fragments. The accuracy of the method is shown to be an improvement over the most widely used tools available and can be run in a constant amount of time when cluster resources are scaled linearly with the amount of input data. Conclusions The cloud offers one solution for the difficulties faced in the analysis of massive high-thoughput sequencing data, which continue to grow rapidly. Researchers in bioinformatics must follow developments in distributed systems–such as new frameworks like Spark–for ways to port existing methods to the cloud and help them scale to the datasets of the future. Our software, eXpress-D, is freely available at: http://github.com/adarob/express-d. PMID:24314033

Position statement. The right to accept or reject an assignment. American Nurses Association.

Science.gov (United States)

1996-01-01

The American Nurses Association (ANA) believes that nurses should reject assignment that puts patients or themselves in serious, immediate jeopardy. ANA supports the nurses obligation to reject an assignment in these situations even where there is not a specific legal protection for rejecting such an assignment. The professional obligations to the nurse to safeguard clients are grounded in the ethical norms of the profession, the Standards of Clinical Nursing Practice and state nurse practice acts.

A Branch-and-Price algorithm for stable workforce assignments with hierarchical skills

NARCIS (Netherlands)

Firat, M.; Briskorn, D.; Laugier, A.

2016-01-01

This paper deals with assigning hierarchically skilled technicians to jobs by considering preferences. We investigate stability definitions in multi-skill workforce assignments stemming from the notion of blocking pairs as stated in the Marriage model of Gale–Shapley. We propose a Branch-and-Price

Statistical methods of spin assignment in compound nuclear reactions

International Nuclear Information System (INIS)

Mach, H.; Johns, M.W.

1984-01-01

Spin assignment to nuclear levels can be obtained from standard in-beam gamma-ray spectroscopy techniques and in the case of compound nuclear reactions can be complemented by statistical methods. These are based on a correlation pattern between level spin and gamma-ray intensities feeding low-lying levels. Three types of intensity and level spin correlations are found suitable for spin assignment: shapes of the excitation functions, ratio of intensity at two beam energies or populated in two different reactions, and feeding distributions. Various empirical attempts are examined and the range of applicability of these methods as well as the limitations associated with them are given. 12 references

Statistical methods of spin assignment in compound nuclear reactions

International Nuclear Information System (INIS)

Mach, H.; Johns, M.W.

1985-01-01

Spin assignment to nuclear levels can be obtained from standard in-beam gamma-ray spectroscopy techniques and in the case of compound nuclear reactions can be complemented by statistical methods. These are based on a correlation pattern between level spin and gamma-ray intensities feeding low-lying levels. Three types of intensity and level spin correlations are found suitable for spin assignment: shapes of the excitation functions, ratio of intensity at two beam energies or populated in two different reactions, and feeding distributions. Various empirical attempts are examined and the range of applicability of these methods as well as the limitations associated with them are given

Examples of geodiversity - biodiversity interactions in the concise guide Inspiration Treasure House Earth, a tool for spatial planning with geodiversity and geoheritage at community level

Science.gov (United States)

van den Ancker, Hanneke; Jungerius, Pieter Dirk; van der Graaff, Evert; de Groof, Arthur; Doornbos, Gerard

2014-05-01

SIKB is a Dutch network organisation, set up to guarantee a minimum quality of soil management. The network encompasses both the private and the public sector. Their activities include the development of decision-making procedures and rendering of services for soil remediation and soil handling, i.a. through standardisation and certification. Each year SIKB produces concise hand-outs to assist and improve soil management. In 2000 the Dutch Ministry of Agriculture then responsible for earth heritage management, commissioned the Stichting Geomorfologie & Landschap to find out how geoheritage and geodiversity were cared for at the community level. The conclusion was that concern for geomorphology, geology, soil and their importance for landscape management and spatial planning was minimal in most Dutch communities. They were only mentioned in the descriptive paragraphs of the local community plan, often very short and using complex terminology not to be understood by any community member. Only in few communities it had resulted in geoheritage protection or attention for preserving the geodiversity of the area. Therefore, in 2007, SIKB and Geoheritage NL produced a hand-out to improve attention for geoheritage and geodiversity at the level of the local community. They produced a concise guide to get geoheritage and geodiversity within the different levels of the spatial plan of the local communities, then called bestemmingsplan now named structuurplan. This hand-out was a success: it had four re-prints and people are still interested in receiving a copy, although it is out of print. Yet, those working with it explained in a special meeting to evaluate the hand-out that it was too thorough a product to inspire decision makers and their colleagues in the local community. Apart from this, SIKB preferred not to make a reprint, but to come with a new product to revive attention. In 2013 we started to develop a hand-out which focusses on examples clarifying why attention for

Dynamic Passenger Assignment during Disruptions in Railway Systems

NARCIS (Netherlands)

Zhu, Y.; Goverde, R.M.P.

2017-01-01

Passenger-oriented rescheduling problems receive increasing attention. However, the passenger assignment models used for evaluating the rescheduling solutions are usually simplified by many assumptions. To estimate passenger inconvenience more accurately, this paper establishes a dynamic passenger

The Impact of a Collaborative Wiki Assignment on Teaching and Learning in a Teacher Education Program

Directory of Open Access Journals (Sweden)

Vanessa Joy Bravo

2011-10-01

Full Text Available This study explored students’ perceptions and behaviors of public wiki use during a collaborative Wikipedia assignment in a graduate technology and literacy education course. Results confirmed that the majority of students had an overall positive experience posting content on Wikipedia. Students learned how to use Wikipedia through collaborative practice, including, how to adhere to its standards and cite work properly, the importance of critically evaluating online information, and the value of publishing work to an authentic audience. Students (prospective and current teachers reported numerous ways in which collaboration on Wikipedia could be integrated into their K-12 classrooms in order to promote higher order thinking and foster meaningful knowledge construction. Pedagogical practices for the effective integration of public wiki assignments in higher education and K-12 settings are recommended.

Teacher-Child Interaction Training: A Pilot Study With Random Assignment.

Science.gov (United States)

Fernandez, Melanie A; Adelstein, Jonathan S; Miller, Samantha P; Areizaga, Margaret J; Gold, Dylann C; Sanchez, Amanda L; Rothschild, Sara A; Hirsch, Emily; Gudiño, Omar G

2015-07-01

Teacher-Child Interaction Training (TCIT), adapted from Parent-Child Interaction Therapy (PCIT), is a classroom-based program designed to provide teachers with behavior management skills that foster positive teacher-student relationships and to improve student behavior by creating a more constructive classroom environment. The purpose of this pilot study was to evaluate TCIT in more classrooms than previously reported in the literature, with older children than previously reported, using random assignment of classrooms to TCIT or to a no-TCIT control condition and conducting all but two sessions within the classroom to enhance feasibility. Participants included 11 kindergarten and first grade classroom teachers and their 118 students from three urban, public schools in Manhattan, with five classrooms randomly assigned to receive TCIT and six to the no-TCIT control condition. Observations of teacher skill acquisition were conducted before, during, and after TCIT for all 11 teachers, and teacher reports of student behavior were obtained at these same time points. Teacher satisfaction with TCIT was assessed following training. Results suggested that after receiving TCIT, teachers increased rates of positive attention to students' appropriate behavior, decreased rates of negative attention to misbehavior, reported significantly less distress related to student disruptive behavior, and reported high satisfaction with the training program. Our study supports the growing evidence-base suggesting that TCIT is a promising approach for training teachers in positive behavior management strategies and for improving student disruptive behavior in the classroom. Copyright © 2015. Published by Elsevier Ltd.

[Clip Sheets from BOCES. Opportunities. Health. Careers. = Oportunidades. Salud. Una Camera En...

Science.gov (United States)

State Univ. of New York, Geneseo. Coll. at Geneseo. Migrant Center.

This collection of 83 clip sheets, or classroom handouts, was created to help U.S. migrants learn more about health, careers, and general "opportunities" including education programs. They are written in both English and Spanish and are presented in an easily understandable format. Health clip-sheet topics include the following: Abuse; AIDS;…

Exploiting Group Symmetry in Semidefinite Programming Relaxations of the Quadratic Assignment Problem

NARCIS (Netherlands)

de Klerk, E.; Sotirov, R.

2007-01-01

We consider semidefinite programming relaxations of the quadratic assignment problem, and show how to exploit group symmetry in the problem data. Thus we are able to compute the best known lower bounds for several instances of quadratic assignment problems from the problem library: [R.E. Burkard,

Accounting for Sustainability: An Active Learning Assignment

Science.gov (United States)

Gusc, Joanna; van Veen-Dirks, Paula

2017-01-01

Purpose: Sustainability is one of the newer topics in the accounting courses taught in university teaching programs. The active learning assignment as described in this paper was developed for use in an accounting course in an undergraduate program. The aim was to enhance teaching about sustainability within such a course. The purpose of this…

Bats.

Science.gov (United States)

Naturescope, 1986

1986-01-01

Presents information about bats, including definitions and descriptions of the characteristics of bats. Provides teaching activities such as "Bat and Math,""A Bat Like That,""Bat Party,""Ears in the Dark," and "The Big Bat Mystery." Contains reproducible handouts and quizzes. (TW)

Teaching Vocabulary in Colour.

Science.gov (United States)

Gnoinska, Anna

1998-01-01

Describes one teacher's use of color to make classroom instruction more interesting. Techniques included using colored paper for handouts, conducting an experiment to see whether the use of colors could enhance students' memory power, and using colored flashcards to teach vocabulary. (Author/VWL)

Assigned value improves memory of proper names.

Science.gov (United States)

Festini, Sara B; Hartley, Alan A; Tauber, Sarah K; Rhodes, Matthew G

2013-01-01

Names are more difficult to remember than other personal information such as occupations. The current research examined the influence of assigned point value on memory and metamemory judgements for names and occupations to determine whether incentive can improve recall of proper names. In Experiment 1 participants studied face-name and face-occupation pairs assigned 1 or 10 points, made judgements of learning, and were given a cued recall test. High-value names were recalled more often than low-value names. However, recall of occupations was not influenced by value. In Experiment 2 meaningless nonwords were used for both names and occupations. The name difficulty disappeared, and value influenced recall of both names and occupations. Thus value similarly influenced names and occupations when meaningfulness was held constant. In Experiment 3 participants were required to use overt rote rehearsal for all items. Value did not boost recall of high-value names, suggesting that differential processing could not be implemented to improve memory. Thus incentives may improve memory for proper names by motivating people to engage in selective rehearsal and effortful elaborative processing.

Psychology Students' Understanding of the Skill-Based Learning Fostered through University Assignments

Science.gov (United States)

Martini, Tanya S.; Rail, Ashley; Norton, Cole

2015-01-01

We examined first-year psychology majors' (N = 195) beliefs about the relevance of two types of university assignments (individual essay and group wiki) and their connection to the development of career-related skills. Students reported that assignments were only somewhat relevant to their career goals, and relevance ratings were typically…

40 CFR 1068.360 - What restrictions apply to assigning a model year to imported engines and equipment?

Science.gov (United States)

2010-07-01

... new engine identified as a 2007 model-year product that is imported on January 31, 2010 will be... equipment? This section includes limitations on assigning a model year to engines and equipment that are imported in a year later than the model year in which they were manufactured, except as specified in...

A method to assign failure rates for piping reliability assessments

International Nuclear Information System (INIS)

Gamble, R.M.; Tagart, S.W. Jr.

1991-01-01

This paper reports on a simplified method that has been developed to assign failure rates that can be used in reliability and risk studies of piping. The method can be applied on a line-by-line basis by identifying line and location specific attributes that can lead to piping unreliability from in-service degradation mechanisms and random events. A survey of service experience for nuclear piping reliability also was performed. The data from this survey provides a basis for identifying in-service failure attributes and assigning failure rates for risk and reliability studies

Waste-aware fluid volume assignment for flow-based microfluidic biochips

DEFF Research Database (Denmark)

Schneider, Alexander Rüdiger; Pop, Paul; Madsen, Jan

2017-01-01

complex Fluidic Units (FUs) such as switches, micropumps, mixers and separators can be constructed. When running a biochemical application on a FBMB, fluid volumes are dispensed from input reservoirs and used by the FUs. Given a biochemical application and a biochip, we are interested in determining...... the fluid volume assignment for each operation of the application, such that the FUs volume requirements are satisfied, while over- and underflow are avoided and the total volume of fluid used is minimized. We propose an algorithm for this fluid assignment problem. Compared to previous work, our method...

Asymmetry in some common assignment algorithms: the dispersion factor solution

OpenAIRE

T de la Barra; B Pérez

1986-01-01

Many common assignment algorithms are based on Dial's original design to determine the paths that trip makers will follow from a given origin to destination centroids. The purpose of this paper is to show that the rules that have to be applied result in two unwanted properties. The first is that trips assigned from an origin centroid i to a destination j can be dramatically different to those resulting from centroid j to centroid i , even if the number of trips is the same and the network is ...

36 CFR 292.22 - Land category assignments.

Science.gov (United States)

2010-07-01

... land. (iv) Commercial land. (2) Not later than August 12, 1994, a map or maps displaying the privately... availability of this map or maps in the local newspapers of record. (b) Changes in land category assignment.../grazing land so long as the intended use or development is consistent with the standards in § 292.23 and...

Fast and accurate taxonomic assignments of metagenomic sequences using MetaBin.

Directory of Open Access Journals (Sweden)

Vineet K Sharma

Full Text Available Taxonomic assignment of sequence reads is a challenging task in metagenomic data analysis, for which the present methods mainly use either composition- or homology-based approaches. Though the homology-based methods are more sensitive and accurate, they suffer primarily due to the time needed to generate the Blast alignments. We developed the MetaBin program and web server for better homology-based taxonomic assignments using an ORF-based approach. By implementing Blat as the faster alignment method in place of Blastx, the analysis time has been reduced by severalfold. It is benchmarked using both simulated and real metagenomic datasets, and can be used for both single and paired-end sequence reads of varying lengths (≥45 bp. To our knowledge, MetaBin is the only available program that can be used for the taxonomic binning of short reads (<100 bp with high accuracy and high sensitivity using a homology-based approach. The MetaBin web server can be used to carry out the taxonomic analysis, by either submitting reads or Blastx output. It provides several options including construction of taxonomic trees, creation of a composition chart, functional analysis using COGs, and comparative analysis of multiple metagenomic datasets. MetaBin web server and a standalone version for high-throughput analysis are available freely at http://metabin.riken.jp/.

Bag-of-features based medical image retrieval via multiple assignment and visual words weighting

KAUST Repository

Wang, Jingyan

2011-11-01

Bag-of-features based approaches have become prominent for image retrieval and image classification tasks in the past decade. Such methods represent an image as a collection of local features, such as image patches and key points with scale invariant feature transform (SIFT) descriptors. To improve the bag-of-features methods, we first model the assignments of local descriptors as contribution functions, and then propose a novel multiple assignment strategy. Assuming the local features can be reconstructed by their neighboring visual words in a vocabulary, reconstruction weights can be solved by quadratic programming. The weights are then used to build contribution functions, resulting in a novel assignment method, called quadratic programming (QP) assignment. We further propose a novel visual word weighting method. The discriminative power of each visual word is analyzed by the sub-similarity function in the bin that corresponds to the visual word. Each sub-similarity function is then treated as a weak classifier. A strong classifier is learned by boosting methods that combine those weak classifiers. The weighting factors of the visual words are learned accordingly. We evaluate the proposed methods on medical image retrieval tasks. The methods are tested on three well-known data sets, i.e., the ImageCLEFmed data set, the 304 CT Set, and the basal-cell carcinoma image set. Experimental results demonstrate that the proposed QP assignment outperforms the traditional nearest neighbor assignment, the multiple assignment, and the soft assignment, whereas the proposed boosting based weighting strategy outperforms the state-of-the-art weighting methods, such as the term frequency weights and the term frequency-inverse document frequency weights. © 2011 IEEE.

Bag-of-features based medical image retrieval via multiple assignment and visual words weighting

KAUST Repository

Wang, Jingyan; Li, Yongping; Zhang, Ying; Wang, Chao; Xie, Honglan; Chen, Guoling; Gao, Xin

2011-01-01

Bag-of-features based approaches have become prominent for image retrieval and image classification tasks in the past decade. Such methods represent an image as a collection of local features, such as image patches and key points with scale invariant feature transform (SIFT) descriptors. To improve the bag-of-features methods, we first model the assignments of local descriptors as contribution functions, and then propose a novel multiple assignment strategy. Assuming the local features can be reconstructed by their neighboring visual words in a vocabulary, reconstruction weights can be solved by quadratic programming. The weights are then used to build contribution functions, resulting in a novel assignment method, called quadratic programming (QP) assignment. We further propose a novel visual word weighting method. The discriminative power of each visual word is analyzed by the sub-similarity function in the bin that corresponds to the visual word. Each sub-similarity function is then treated as a weak classifier. A strong classifier is learned by boosting methods that combine those weak classifiers. The weighting factors of the visual words are learned accordingly. We evaluate the proposed methods on medical image retrieval tasks. The methods are tested on three well-known data sets, i.e., the ImageCLEFmed data set, the 304 CT Set, and the basal-cell carcinoma image set. Experimental results demonstrate that the proposed QP assignment outperforms the traditional nearest neighbor assignment, the multiple assignment, and the soft assignment, whereas the proposed boosting based weighting strategy outperforms the state-of-the-art weighting methods, such as the term frequency weights and the term frequency-inverse document frequency weights. © 2011 IEEE.

Whether and How to Select Inertia and Acceleration of Discrete Particle Swarm Optimization Algorithm: A Study on Channel Assignment

Directory of Open Access Journals (Sweden)

Min Jin

2014-01-01

Full Text Available There is recently a great deal of interest and excitement in understanding the role of inertia and acceleration in the motion equation of discrete particle swarm optimization (DPSO algorithms. It still remains unknown whether the inertia section should be abandoned and how to select the appropriate acceleration in order for DPSO to show the best convergence performance. Adopting channel assignment as a case study, this paper systematically conducts experimental filtering research on this issue. Compared with other channel assignment schemes, the proposed scheme and the selection of inertia and acceleration are verified to have the advantage to channel assignment in three respects of convergence rate, convergence speed, and the independency of the quality of initial solution. Furthermore, the experimental result implies that DSPO might have the best convergence performance when its motion equation includes an inertia section in a less medium weight, a bigger acceleration coefficient for global-search optimum, and a smaller acceleration coefficient for individual-search optimum.

Stereospecific assignments of glycine in proteins by stereospecific deuteration and {sup 15}N labeling

Energy Technology Data Exchange (ETDEWEB)

Hansen, A.P.; Curley, R.W. Jr.; Panigot, M.J.; Fesik, S.W. [Ohio State Univ., Columbus, OH (United States)

1994-12-01

Stereospecific assignments are important for accurately determining the three-dimensional structures of proteins through the use of multidimensional NMR techniques. It is especially important to stereospecifically assign the glycine {alpha}-protons in proteins because of the potential for different backbone conformations of this residue. These stereospecific assignments are critical for interpreting the {sup 3}J{sub NH,{alpha}H} coupling constants and NOEs involving the glycine {alpha}-protons that determine the conformation of this part of the protein. However, it is often difficult to unambiguously obtain the stereospecific assignments for glycine residues by using only NOE data. In this poster, we present a method for unambiguous, stereospecific assignment of the {alpha}-protons of glycine residues. This method involves synthesis of stereo-specifically deuterated and {sup 15}N-labeled Gly using a slightly modified procedure originally described by Woodard and coworkers for the stereoselective deuteration of glycine. The stereospecifically deuterated and {sup 15}N-labeled Gy has been incorporated into recombinant proteins expressed in both bacterial systems (FKBP) and mammalian cells (u-PA). Two- and three-dimensional isotope-filtered and isotope-edited NMR experiments were used to obtain the stereospecific assignments of the glycine {alpha}-protons for these proteins.

Final Evaluation of Assignment: Media Literacy. A Report to the Discovery Channel.

Science.gov (United States)

Kubey, Robert; Serafin, Gina Marcello

The Assignment: Media Literacy curriculum is a 6-module media literacy curriculum developed by Renee Hobbs of Babson College and her staff in collaboration with the Discovery Channel. There are three versions of Assignment: Media Literacy, one for elementary school students, one for middle school students, and one for high school students. Close…

Gender identity, gender assignment and reassignment in individuals with disorders of sex development: a major of dilemma.

Science.gov (United States)

Fisher, A D; Ristori, J; Fanni, E; Castellini, G; Forti, G; Maggi, M

2016-11-01

Disorders of Sex Development (DSD) are a wide range of congenital conditions characterized by an incongruence of components involved in sexual differentiation, including gender psychosexual development. The management of such disorders is complex, and one of the most crucial decision is represented by gender assignment. In fact, the primary goal in DSD is to have a gender assignment consistent with the underlying gender identity in order to prevent the distress related to a forthcoming Gender Dysphoria. Historically, gender assignment was based essentially on surgical outcomes, assuming the neutrality of gender identity at birth. This policy has been challenged in the past decade refocusing on the importance of prenatal and postnatal hormonal and genetic influences on psychosexual development. (1) to update the main psychological and medical issues that surround DSD, in particular regarding gender identity and gender assignment; (2) to report specific clinical recommendations according to the different diagnosis. A systematic search of published evidence was performed using Medline (from 1972 to March 2016). Review of the relevant literature and recommendations was based on authors' expertise. A review of gender identity and assignment in DSD is provided as well as clinical recommendations for the management of individuals with DSD. Given the complexity of this management, DSD individuals and their families need to be supported by a specialized multidisciplinary team, which has been universally recognized as the best practice for intersexual conditions. In case of juvenile GD in DSD, the prescription of gonadotropin-releasing hormone analogues, following the World Professional Association for Transgender Health and the Endocrine Society guidelines, should be considered. It should always be taken into account that every DSD person is unique and has to be treated with individualized care. In this perspective, international registries are crucial to improve the

DNA barcode data accurately assign higher spider taxa

Directory of Open Access Journals (Sweden)

Jonathan A. Coddington

2016-07-01

Full Text Available The use of unique DNA sequences as a method for taxonomic identification is no longer fundamentally controversial, even though debate continues on the best markers, methods, and technology to use. Although both existing databanks such as GenBank and BOLD, as well as reference taxonomies, are imperfect, in best case scenarios “barcodes” (whether single or multiple, organelle or nuclear, loci clearly are an increasingly fast and inexpensive method of identification, especially as compared to manual identification of unknowns by increasingly rare expert taxonomists. Because most species on Earth are undescribed, a complete reference database at the species level is impractical in the near term. The question therefore arises whether unidentified species can, using DNA barcodes, be accurately assigned to more inclusive groups such as genera and families—taxonomic ranks of putatively monophyletic groups for which the global inventory is more complete and stable. We used a carefully chosen test library of CO1 sequences from 49 families, 313 genera, and 816 species of spiders to assess the accuracy of genus and family-level assignment. We used BLAST queries of each sequence against the entire library and got the top ten hits. The percent sequence identity was reported from these hits (PIdent, range 75–100%. Accurate assignment of higher taxa (PIdent above which errors totaled less than 5% occurred for genera at PIdent values >95 and families at PIdent values ≥ 91, suggesting these as heuristic thresholds for accurate generic and familial identifications in spiders. Accuracy of identification increases with numbers of species/genus and genera/family in the library; above five genera per family and fifteen species per genus all higher taxon assignments were correct. We propose that using percent sequence identity between conventional barcode sequences may be a feasible and reasonably accurate method to identify animals to family/genus. However

Modelling the Preferences of Students for Alternative Assignment Designs Using the Discrete Choice Experiment Methodology

Directory of Open Access Journals (Sweden)

Brendan Kennelly

2014-11-01

Full Text Available This paper outlines how a discrete choice experiment (DCE can be used to learn more about how students are willing to trade off various features of assignments such as the nature and timing of feedback and the method used to submit assignments. A DCE identifies plausible levels of the key attributes of a good or service and then presents the respondent with alternative bundles of these attributes and their levels and asks the respondent to choose between particular bundles. We report results from a DCE we conducted with undergraduate business students regarding their preferences for assignment systems. We find that the most important features of assignments are how relevant the assignments are for exam preparation and the nature of the feedback that students receive. We also find that students generally prefer online to paper assignments. We argue that the DCE approach has a lot of potential in education research.

A Review on Eigenstructure Assignment Methods and Orthogonal Eigenstructure Control of Structural Vibrations

Directory of Open Access Journals (Sweden)

Mohammad Rastgaar

2009-01-01

Full Text Available This paper provides a state-of-the-art review of eigenstructure assignment methods for vibration cancellation. Eigenstructure assignment techniques have been widely used during the past three decades for vibration suppression in structures, especially in large space structures. These methods work similar to mode localization in which global vibrations are managed such that they remain localized within the structure. Such localization would help reducing vibrations more effectively than other methods of vibration cancellation, by virtue of confining the vibrations close to the source of disturbance. The common objective of different methods of eigenstructure assignment is to provide controller design freedom beyond pole placement, and define appropriate shapes for the eigenvectors of the systems. These methods; however, offer a large and complex design space of options that can often overwhelm the control designer. Recent developments in orthogonal eigenstructure control offers a significant simplification of the design task while allowing some experience-based design freedom. The majority of the papers from the past three decades in structural vibration cancellation using eigenstructure assignment methods are reviewed, along with recent studies that introduce new developments in eigenstructure assignment techniques.

De novo protein structure generation from incomplete chemical shift assignments

Energy Technology Data Exchange (ETDEWEB)

Shen Yang [National Institutes of Health, Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases (United States); Vernon, Robert; Baker, David [University of Washington, Department of Biochemistry and Howard Hughes Medical Institute (United States); Bax, Ad [National Institutes of Health, Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases (United States)], E-mail: bax@nih.gov

2009-02-15

NMR chemical shifts provide important local structural information for proteins. Consistent structure generation from NMR chemical shift data has recently become feasible for proteins with sizes of up to 130 residues, and such structures are of a quality comparable to those obtained with the standard NMR protocol. This study investigates the influence of the completeness of chemical shift assignments on structures generated from chemical shifts. The Chemical-Shift-Rosetta (CS-Rosetta) protocol was used for de novo protein structure generation with various degrees of completeness of the chemical shift assignment, simulated by omission of entries in the experimental chemical shift data previously used for the initial demonstration of the CS-Rosetta approach. In addition, a new CS-Rosetta protocol is described that improves robustness of the method for proteins with missing or erroneous NMR chemical shift input data. This strategy, which uses traditional Rosetta for pre-filtering of the fragment selection process, is demonstrated for two paramagnetic proteins and also for two proteins with solid-state NMR chemical shift assignments.

Performance evaluation of distributed wavelength assignment in WDM optical networks

Science.gov (United States)

Hashiguchi, Tomohiro; Wang, Xi; Morikawa, Hiroyuki; Aoyama, Tomonori

2004-04-01

In WDM wavelength routed networks, prior to a data transfer, a call setup procedure is required to reserve a wavelength path between the source-destination node pairs. A distributed approach to a connection setup can achieve a very high speed, while improving the reliability and reducing the implementation cost of the networks. However, along with many advantages, several major challenges have been posed by the distributed scheme in how the management and allocation of wavelength could be efficiently carried out. In this thesis, we apply a distributed wavelength assignment algorithm named priority based wavelength assignment (PWA) that was originally proposed for the use in burst switched optical networks to the problem of reserving wavelengths of path reservation protocols in the distributed control optical networks. Instead of assigning wavelengths randomly, this approach lets each node select the "safest" wavelengths based on the information of wavelength utilization history, thus unnecessary future contention is prevented. The simulation results presented in this paper show that the proposed protocol can enhance the performance of the system without introducing any apparent drawbacks.

Efficient Stereospecific Hβ2/3 NMR Assignment Strategy for Mid-Size Proteins

Directory of Open Access Journals (Sweden)

Alexandra Born

2018-06-01

Full Text Available We present a strategy for stereospecific NMR assignment of Hβ2 and Hβ3 protons in mid-size proteins (~150 residues. For such proteins, resonance overlap in standard experiments is severe, thereby preventing unambiguous assignment of a large fraction of β-methylenes. To alleviate this limitation, assignment experiments may be run in high static fields, where higher decoupling power is required. Three-bond Hα–Hβ J-couplings (3JHα–Hβ are critical for stereospecific assignments of β-methylene protons, and for determining rotameric χ1 states. Therefore, we modified a pulse sequence designed to measure accurate 3JHα–Hβ couplings such that probe heating was reduced, while the decoupling performance was improved. To further increase the resolution, we applied non-uniform sampling (NUS schemes in the indirect 1H and 13C dimensions. The approach was applied to two medium-sized proteins, odorant binding protein 22 (OBP22; 14.4 kDa and Pin1 (18.2 kDa, at 900 MHz polarizing fields. The coupling values obtained from NUS and linear sampling were extremely well correlated. However, NUS decreased the overlap of Hβ2/3 protons, thus supplying a higher yield of extracted 3JHα-Hβ coupling values when compared with linear sampling. A similar effect could be achieved with linear prediction applied to the linearly sampled data prior to the Fourier transformation. Finally, we used 3JHα–Hβ couplings from Pin1 in combination with either conventional or exact nuclear Overhauser enhancement (eNOE restraints to determine the stereospecific assignments of β-methylene protons. The use of eNOEs further increased the fraction of unambiguously assigned resonances when compared with procedures using conventional NOEs.

Scalable Task Assignment for Heterogeneous Multi-Robot Teams

Directory of Open Access Journals (Sweden)

Paula García

2013-02-01

Full Text Available This work deals with the development of a dynamic task assignment strategy for heterogeneous multi-robot teams in typical real world scenarios. The strategy must be efficiently scalable to support problems of increasing complexity with minimum designer intervention. To this end, we have selected a very simple auction-based strategy, which has been implemented and analysed in a multi-robot cleaning problem that requires strong coordination and dynamic complex subtask organization. We will show that the selection of a simple auction strategy provides a linear computational cost increase with the number of robots that make up the team and allows the solving of highly complex assignment problems in dynamic conditions by means of a hierarchical sub-auction policy. To coordinate and control the team, a layered behaviour-based architecture has been applied that allows the reusing of the auction-based strategy to achieve different coordination levels.

P-wave assignment of 232Th neutron resonances

International Nuclear Information System (INIS)

Corvi, F.; Pasquariello, G.; Veen, T. van der

1978-01-01

A method of p-wave assignment which exploits the parity dependence of the primary capture γ-ray spectrum was applied to the 232 Th resonance. The yield of capture γ-rays above 4.4 MeV from a 6 mm thick metallic thorium disk was measured in the neutron energy range 20-2200 eV and compared to a similar run with γ-rays in the range 3.7 - 4.4 MeV. A total of 58 resonances showing an enhancement of the high energy γ-ray yield were assigned as p-waves. Assuming that their reduced neutron widths follow a Porter-Thomas distribution, their average value and then the p-wave strength function S 1 were estimated with a maximum likelihood method. The results are: average neutron width=3.4(+0.8 or -0.6)meV; S 1 = 2.0 (+0.5 or -0.4).10 -4

Agreement between diagnoses of childhood lymphoma assigned in Uganda and by an international reference laboratory

Directory of Open Access Journals (Sweden)

Orem J

2012-12-01

Full Text Available Jackson Orem,1–3 Sven Sandin,1 Caroline E Weibull,1 Michael Odida,4 Henry Wabinga,4 Edward Mbidde,2,3 Fred Wabwire-Mangen,5 Chris JLM Meijer,6 Jaap M Middeldorp,6 Elisabete Weiderpass1,7,81Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 2Uganda Cancer Institute, 3School of Medicine, 4School of Biomedical Sciences, 5School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda; 6Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands; 7Cancer Registry of Norway, Oslo; Department of Community Medicine, University of Tromsø, Tromsø, Norway; 8Samfundet Folkhälsan, Helsinki, FinlandBackground: Correct diagnosis is key to appropriate treatment of cancer in children. However, diagnostic challenges are common in low-income and middle-income countries. The objective of the present study was to assess the agreement between a clinical diagnosis of childhood non-Hodgkin lymphoma (NHL assigned in Uganda, a pathological diagnosis assigned in Uganda, and a pathological diagnosis assigned in The Netherlands.Methods: The study included children with suspected NHL referred to the Mulago National Referral Hospital, Kampala, Uganda, between 2004 and 2008. A clinical diagnosis was assigned at the Mulago National Referral Hospital, where tissue samples were also obtained. Hematoxylin and eosin-stained slides were used for histological diagnosis in Uganda, and were re-examined in a pathology laboratory in The Netherlands, where additional pathological, virological and serological testing was also carried out. Agreement between diagnostic sites was compared using kappa statistics.Results: Clinical and pathological diagnoses from Uganda and pathological diagnosis from The Netherlands was available for 118 children. The agreement between clinical and pathological diagnoses of NHL assigned in Uganda was 91% (95% confidence interval [CI] 84–95; kappa 0.84; P < 0

Modeling multiple visual words assignment for bag-of-features based medical image retrieval

KAUST Repository

Wang, Jim Jing-Yan

2012-01-01

In this paper, we investigate the bag-of-features based medical image retrieval methods, which represent an image as a collection of local features, such as image patch and key points with SIFT descriptor. To improve the bag-of-features method, we first model the assignment of local descriptor as contribution functions, and then propose a new multiple assignment strategy. By assuming the local feature can be reconstructed by its neighboring visual words in vocabulary, we solve the reconstruction weights as a QP problem and then use the solved weights as contribution functions, which results in a new assignment method called the QP assignment. We carry our experiments on ImageCLEFmed datasets. Experiments\\' results show that our proposed method exceeds the performances of traditional solutions and works well for the bag-of-features based medical image retrieval tasks.

Modeling multiple visual words assignment for bag-of-features based medical image retrieval

KAUST Repository

Wang, Jim Jing-Yan; Almasri, Islam

2012-01-01

In this paper, we investigate the bag-of-features based medical image retrieval methods, which represent an image as a collection of local features, such as image patch and key points with SIFT descriptor. To improve the bag-of-features method, we first model the assignment of local descriptor as contribution functions, and then propose a new multiple assignment strategy. By assuming the local feature can be reconstructed by its neighboring visual words in vocabulary, we solve the reconstruction weights as a QP problem and then use the solved weights as contribution functions, which results in a new assignment method called the QP assignment. We carry our experiments on ImageCLEFmed datasets. Experiments' results show that our proposed method exceeds the performances of traditional solutions and works well for the bag-of-features based medical image retrieval tasks.

Differences in motivation and adherence to a prescribed assignment after face-to-face and online psychoeducation: an experimental study.

Science.gov (United States)

Alfonsson, Sven; Johansson, Karin; Uddling, Jonas; Hursti, Timo

2017-01-26

Adherence to treatment homework is associated with positive outcomes in behavioral psychotherapy but compliance to assignments is still often moderate. Whether adherence can be predicted by different types of motivation for the task and whether motivation plays different roles in face-to-face compared to online psychotherapy is unknown. If models of motivation, such as Self-determination theory, can be used to predict patients' behavior, it may facilitate further research into homework promotion. The aims of this study were, therefore, to investigate whether motivation variables could predict adherence to a prescribed assignment in face-to-face and online interventions using a psychotherapy analog model. A total of 100 participants were included in this study and randomized to either a face-to-face or online intervention. Participants in both groups received a psychoeducation session and were given an assignment for the subsequent week. The main outcome measurements were self-reported motivation and adherence to the assignment. Participant in the face-to-face condition reported significantly higher levels of motivation and showed higher levels of adherence compared to participants in the online condition. Adherence to the assignment was positively associated with intrinsic motivation and intervention credibility in the whole sample and especially in the online group. This study shows that intrinsic motivation and intervention credibility are strong predictors of adherence to assignments, especially in online interventions. The results indicate that intrinsic motivation may be partly substituted with face-to-face contact with a therapist. It may also be possible to identify patients with low motivation in online interventions who are at risk of dropping out. Methods for making online interventions more intrinsically motivating without increasing external pressure are needed. clinicaltrials.gov NCT02895308 . Retrospectively registered 30 August 2016.

Characterizing Sailor and Command Enlisted Placement and Assignment Preferences

National Research Council Canada - National Science Library

Butler, Virginia

2002-01-01

.... DON currently matches sailors to billets using a labor-intensive detailing process. With evolving information technology, the assignment process could be accomplished using intelligent agents and web-based markets...

Appendix B: Site Visit Reports. Assessment of Research Needs for Coal Utilization

Energy Technology Data Exchange (ETDEWEB)

Penner, S.S.

1983-05-01

This section contains edited copies of site-visit and other reports prepared by CCAWG members. Some of the hand-out materials prepared by DOE contractors and others are included (without explication) to permit readers the construction of a coherent picture of work in progress.

Ammonia. Training Module 5.110.2.77.

Science.gov (United States)

Kirkwood Community Coll., Cedar Rapids, IA.

This document is an instructional module package prepared in objective form for use by an instructor familiar with analytical procedures for determining ammonia nitrogen concentrations in a water or wastewater sample. Included are objectives, instructor guides, student handouts, and transparency masters. This module considers preliminary…

The effect of an interactive e-drug calculations package on nursing students' drug calculation ability and self-efficacy.

Science.gov (United States)

McMullan, Miriam; Jones, Ray; Lea, Susan

2011-06-01

Nurses need to be competent and confident in performing drug calculations to ensure patient safety. The purpose of this study is to compare an interactive e-drug calculations package, developed using Cognitive Load Theory as its theoretical framework, with traditional handout learning support on nursing students' drug calculation ability, self-efficacy and support material satisfaction. A cluster randomised controlled trial comparing the e-package with traditional handout learning support was conducted with a September cohort (n=137) and a February cohort (n=92) of second year diploma nursing students. Students from each cohort were geographically dispersed over 3 or 4 independent sites. Students from each cohort were invited to participate, halfway through their second year, before and after a 12 week clinical practice placement. During their placement the intervention group received the e-drug calculations package while the control group received traditional 'handout' support material. Drug calculation ability and self-efficacy tests were given to the participants pre- and post-intervention. Participants were given the support material satisfaction scale post-intervention. Students in both cohorts randomised to e-learning were more able to perform drug calculations than those receiving the handout (September: mean 48.4% versus 34.7%, p=0.027; February: mean 47.6% versus 38.3%, p=0.024). February cohort students using the e-package were more confident in performing drug calculations than those students using handouts (self-efficacy mean 56.7% versus 45.8%, p=0.022). There was no difference in improved self-efficacy between intervention and control for students in the September cohort. Students who used the package were more satisfied with its use than the students who used the handout (mean 29.6 versus 26.5, p=0.001), particularly with regard to the package enhancing their learning (p=0.023), being an effective way to learn (p=0.005), providing practice and

Spin assignment and behavior of superdeformed bands in A∼150 mass region

International Nuclear Information System (INIS)

Khalaf, A.; Sirag, M.; Taha, M.

2012-01-01

The smoothed experimental dynamical moment of inertia J (2) values were fitted with a theoretical version depend on Harris three parameter formula in even power of angular frequency ω, derived for results from cranking model. The expansion parameters were adjusted by using a computer simulated search program. The best expansion parameters from the fit were used to assign the spins of the superdeformed ( SD ) rotational bands (RB ) by integrating the calculated J (2) . The data set include 23 RB's in 11 SD nuclei, which show no evidence of either irregular behavior near the bottom of the bands or abrupt angular momentum at low rotational frequency in the mass region ranging from A= 142 to A = 154. we used the differences of angular momenta at constant frequency as effective alignment. The relative properties of superdeformed rotational bands (SDRB's) are analyzed in terms of the effective alignment of the valence nucleons. The effective alignment is a powerful tool to assign the configurations, to select the identical bands as well as to predict new SD bands from other combination of the orbitals. The ΔI = 2 energy staggering observed in 3 of our selected SDRB's are also described from a smooth reference representing the finite difference approximation to the fourth derivative of the γ-ray transition energies.

Symmetric Logic Synthesis with Phase Assignment

OpenAIRE

Benschop, N. F.

2001-01-01

Decomposition of any Boolean Function BF_n of n binary inputs into an optimal inverter coupled network of Symmetric Boolean functions SF_k (k \\leq n) is described. Each SF component is implemented by Threshold Logic Cells, forming a complete and compact T-Cell Library. Optimal phase assignment of input polarities maximizes local symmetries. The "rank spectrum" is a new BF_n description independent of input ordering, obtained by mapping its minterms onto an othogonal n \\times n grid of (transi...

Stereospecific assignment of the asparagine and glutamine sidechain amide protons in proteins from chemical shift analysis

Energy Technology Data Exchange (ETDEWEB)

Harsch, Tobias; Schneider, Philipp; Kieninger, Bärbel; Donaubauer, Harald; Kalbitzer, Hans Robert, E-mail: hans-robert.kalbitzer@biologie.uni-regensburg.de [University of Regensburg, Institute of Biophysics and Physical Biochemistry and Centre of Magnetic Resonance in Chemistry and Biomedicine (Germany)

2017-02-15

Side chain amide protons of asparagine and glutamine residues in random-coil peptides are characterized by large chemical shift differences and can be stereospecifically assigned on the basis of their chemical shift values only. The bimodal chemical shift distributions stored in the biological magnetic resonance data bank (BMRB) do not allow such an assignment. However, an analysis of the BMRB shows, that a substantial part of all stored stereospecific assignments is not correct. We show here that in most cases stereospecific assignment can also be done for folded proteins using an unbiased artificial chemical shift data base (UACSB). For a separation of the chemical shifts of the two amide resonance lines with differences ≥0.40 ppm for asparagine and differences ≥0.42 ppm for glutamine, the downfield shifted resonance lines can be assigned to H{sup δ21} and H{sup ε21}, respectively, at a confidence level >95%. A classifier derived from UASCB can also be used to correct the BMRB data. The program tool AssignmentChecker implemented in AUREMOL calculates the Bayesian probability for a given stereospecific assignment and automatically corrects the assignments for a given list of chemical shifts.

An Ultimatum Game Approach to Billet Assignments

Science.gov (United States)

2015-09-01

time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed , and completing and reviewing this...treatments are needed for this investigation. To conserve the subject pool and meet the budget, we elected to pursue treatments that covered salient...across billets can be partially offset through compensating wages ( hedonic wages) and/or the potential of future superior assignments. In the

RUPS: Research Utilizing Problem Solving. Administrators Version. Participant Materials.

Science.gov (United States)

Jung, Charles; And Others

These materials are the handouts for school administrators participating in RUPS (Research Utilizing Problem Solving) workshops. The purposes of the workshops are to develop skills for improving schools and to increase teamwork skills. The handouts correspond to the 16 subsets that make up the five-day workshop: (1) orientation; (2) identifying…

Computational assignment of redox states to Coulomb blockade diamonds.

Science.gov (United States)

Olsen, Stine T; Arcisauskaite, Vaida; Hansen, Thorsten; Kongsted, Jacob; Mikkelsen, Kurt V

2014-09-07

With the advent of molecular transistors, electrochemistry can now be studied at the single-molecule level. Experimentally, the redox chemistry of the molecule manifests itself as features in the observed Coulomb blockade diamonds. We present a simple theoretical method for explicit construction of the Coulomb blockade diamonds of a molecule. A combined quantum mechanical/molecular mechanical method is invoked to calculate redox energies and polarizabilities of the molecules, including the screening effect of the metal leads. This direct approach circumvents the need for explicit modelling of the gate electrode. From the calculated parameters the Coulomb blockade diamonds are constructed using simple theory. We offer a theoretical tool for assignment of Coulomb blockade diamonds to specific redox states in particular, and a study of chemical details in the diamonds in general. With the ongoing experimental developments in molecular transistor experiments, our tool could find use in molecular electronics, electrochemistry, and electrocatalysis.

Mining Staff Assignment Rules from Event-Based Data

NARCIS (Netherlands)

Ly, Linh Thao; Rinderle, Stefanie; Dadam, Peter; Reichert, Manfred; Bussler, Christoph J.; Haller, Armin

2006-01-01

Process mining offers methods and techniques for capturing process behaviour from log data of past process executions. Although many promising approaches on mining the control flow have been published, no attempt has been made to mine the staff assignment situation of business processes. In this

77 FR 8174 - EPAAR Prescription for Work Assignments

Science.gov (United States)

2012-02-14

... because it does not affect the level of protection provided to human health or the environment. This rulemaking does not involve human health or environmental affects. K. Congressional Review Act The... Prescription for Work Assignments AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule. SUMMARY...

Design of an adaptive pole assignment controller for steam generators and its experimental study

International Nuclear Information System (INIS)

Na, Man Gyun; No, Hee Cheon

1992-01-01

An adaptive observer is designed that both parameters and state variables of the steam generator are estimated simultaneously. A pole assignment controller is derived on the basis of the adaptive observer. The characteristics of the overall closed-loop control system can be expressed in terms of its poles, assigned poles. The troublesome tuning procedure of the P-I controller is reduced to the determination of the desired poles only. The proposed algorithm is compared with the conventional P-I controller through numerical simulation. Also, the adaptive pole assignment controller is studied experimentally by implementing it to the mock-up of the nuclear steam generator. The adaptive pole assignment controller shows better responses than the P-l controller does. (Author)

Minimum Interference Channel Assignment Algorithm for Multicast in a Wireless Mesh Network

Directory of Open Access Journals (Sweden)

Sangil Choi

2016-12-01

Full Text Available Wireless mesh networks (WMNs have been considered as one of the key technologies for the configuration of wireless machines since they emerged. In a WMN, wireless routers provide multi-hop wireless connectivity between hosts in the network and also allow them to access the Internet via gateway devices. Wireless routers are typically equipped with multiple radios operating on different channels to increase network throughput. Multicast is a form of communication that delivers data from a source to a set of destinations simultaneously. It is used in a number of applications, such as distributed games, distance education, and video conferencing. In this study, we address a channel assignment problem for multicast in multi-radio multi-channel WMNs. In a multi-radio multi-channel WMN, two nearby nodes will interfere with each other and cause a throughput decrease when they transmit on the same channel. Thus, an important goal for multicast channel assignment is to reduce the interference among networked devices. We have developed a minimum interference channel assignment (MICA algorithm for multicast that accurately models the interference relationship between pairs of multicast tree nodes using the concept of the interference factor and assigns channels to tree nodes to minimize interference within the multicast tree. Simulation results show that MICA achieves higher throughput and lower end-to-end packet delay compared with an existing channel assignment algorithm named multi-channel multicast (MCM. In addition, MICA achieves much lower throughput variation among the destination nodes than MCM.

The use of writing assignments to help students synthesize content in upper-level undergraduate biology courses.

Science.gov (United States)

Sparks-Thissen, Rebecca L

2017-02-01

Biology education is undergoing a transformation toward a more student-centered, inquiry-driven classroom. Many educators have designed engaging assignments that are designed to help undergraduate students gain exposure to the scientific process and data analysis. One of these types of assignments is use of a grant proposal assignment. Many instructors have used these assignments in lecture-based courses to help students process information in the literature and apply that information to a novel problem such as design of an antiviral drug or a vaccine. These assignments have been helpful in engaging students in the scientific process in the absence of an inquiry-driven laboratory. This commentary discusses the application of these grant proposal writing assignments to undergraduate biology courses. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

[Rapid assessment of critical quality attributes of Chinese materia medica (II): strategy of NIR assignment].

Science.gov (United States)

Pei, Yan-Ling; Wu, Zhi-Sheng; Shi, Xin-Yuan; Zhou, Lu-Wei; Qiao, Yan-Jiang

2014-09-01

The present paper firstly reviewed the research progress and main methods of NIR spectral assignment coupled with our research results. Principal component analysis was focused on characteristic signal extraction to reflect spectral differences. Partial least squares method was concerned with variable selection to discover characteristic absorption band. Two-dimensional correlation spectroscopy was mainly adopted for spectral assignment. Autocorrelation peaks were obtained from spectral changes, which were disturbed by external factors, such as concentration, temperature and pressure. Density functional theory was used to calculate energy from substance structure to establish the relationship between molecular energy and spectra change. Based on the above reviewed method, taking a NIR spectral assignment of chlorogenic acid as example, a reliable spectral assignment for critical quality attributes of Chinese materia medica (CMM) was established using deuterium technology and spectral variable selection. The result demonstrated the assignment consistency according to spectral features of different concentrations of chlorogenic acid and variable selection region of online NIR model in extract process. Although spectral assignment was initial using an active pharmaceutical ingredient, it is meaningful to look forward to the futurity of the complex components in CMM. Therefore, it provided methodology for NIR spectral assignment of critical quality attributes in CMM.

A branch-and-cut algorithm for the Time Window Assignment Vehicle Routing Problem

NARCIS (Netherlands)

K. Dalmeijer (Kevin); R. Spliet (Remy)

2016-01-01

textabstractThis paper presents a branch-and-cut algorithm for the Time Window Assignment Vehicle Routing Problem (TWAVRP), the problem of assigning time windows for delivery before demand volume becomes known. A novel set of valid inequalities, the precedence inequalities, is introduced and

Persuasive texts for prompting action: Agency assignment in HPV vaccination reminders.

Science.gov (United States)

McGlone, Matthew S; Stephens, Keri K; Rodriguez, Serena A; Fernandez, Maria E

2017-08-03

Vaccination reminders must both inform and persuade, and text messages designed for this purpose must do so in 160 characters or less. We tested a strategy for improving the impact of HPV vaccination text message reminders through strategic wording. In an experiment conducted in community settings, 167 Spanish-speaking Latina mothers reviewed text message reminders that assigned the cause or "agency" for HPV transmission to their daughters or the virus, and assigned protection agency to the mothers or the vaccine. Reminder messages framing transmission as an action of the virus prompted mothers to perceive the threat as more severe than messages describing their daughters as the cause. Assigning transmission agency to the virus also held a persuasive advantage in boosting mothers' intentions to seek vaccination, particularly when the message cast mothers as agents of protection rather than the vaccine. Copyright © 2017 Elsevier Ltd. All rights reserved.

33 CFR 5.33 - Training, examination, and assignment.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Training, examination, and... GENERAL COAST GUARD AUXILIARY § 5.33 Training, examination, and assignment. The Commandant will prescribe the type of training, qualifications and examinations required before a member of the Auxiliary shall...

Contextual effects on perceived contrast: figure-ground assignment and orientation contrast.

Science.gov (United States)

Self, Matthew W; Mookhoek, Aart; Tjalma, Nienke; Roelfsema, Pieter R

2015-02-02

Figure-ground segregation is an important step in the path leading to object recognition. The visual system segregates objects ('figures') in the visual scene from their backgrounds ('ground'). Electrophysiological studies in awake-behaving monkeys have demonstrated that neurons in early visual areas increase their firing rate when responding to a figure compared to responding to the background. We hypothesized that similar changes in neural firing would take place in early visual areas of the human visual system, leading to changes in the perception of low-level visual features. In this study, we investigated whether contrast perception is affected by figure-ground assignment using stimuli similar to those in the electrophysiological studies in monkeys. We measured contrast discrimination thresholds and perceived contrast for Gabor probes placed on figures or the background and found that the perceived contrast of the probe was increased when it was placed on a figure. Furthermore, we tested how this effect compared with the well-known effect of orientation contrast on perceived contrast. We found that figure-ground assignment and orientation contrast produced changes in perceived contrast of a similar magnitude, and that they interacted. Our results demonstrate that figure-ground assignment influences perceived contrast, consistent with an effect of figure-ground assignment on activity in early visual areas of the human visual system. © 2015 ARVO.

Protein secondary structure: category assignment and predictability

DEFF Research Database (Denmark)

Andersen, Claus A.; Bohr, Henrik; Brunak, Søren

2001-01-01

In the last decade, the prediction of protein secondary structure has been optimized using essentially one and the same assignment scheme known as DSSP. We present here a different scheme, which is more predictable. This scheme predicts directly the hydrogen bonds, which stabilize the secondary......-forward neural network with one hidden layer on a data set identical to the one used in earlier work....

Stress Assignment in N+N Combinations in Arabic

Directory of Open Access Journals (Sweden)

Abdel Rahman Mitib Altakhaineh

2017-09-01

Full Text Available The validity of stress as a criterion to distinguish between compounds and phrases has been investigated in many languages, including English (see e.g. Lieber 2005: 376; Booij 2012: 84. However, the possibility of using stress as a criterion in this way has not been investigated for Arabic. Siloni (1997: 21 claims that in N+N combinations in Semitic languages, stress always falls on the second element. However, the results of a study using PRAAT reveal that, in Modern Standard Arabic (MSA and Jordanian Arabic (JA, stress plays no role in distinguishing between various N+N combinations, i.e. compounds and phrases, e.g.ˈmuʕallim lfiizyaaʔ ‘the physics teacher’ vs.ˈbayt lwalad ‘the boy’s house’, respectively. Analysis shows that the default position of stress in N+N combinations in MSA and JA is on the first element. There is only one systematic exception, which is phonetically conditioned: in N+N combinations with assimilated geminates on the word boundary, a secondary stress or perhaps double stress is assigned.

Using cooperative learning for a drug information assignment.

Science.gov (United States)

Earl, Grace L

2009-11-12

To implement a cooperative learning activity to engage students in analyzing tertiary drug information resources in a literature evaluation course. The class was divided into 4 sections to form expert groups and each group researched a different set of references using the jigsaw technique. Each member of each expert group was reassigned to a jigsaw group so that each new group was composed of 4 students from 4 different expert groups. The jigsaw groups met to discuss search strategies and rate the usefulness of the references. In addition to group-based learning, teaching methods included students' writing an independent research paper to enhance their abilities to search and analyze drug information resources. The assignment and final course grades improved after implementation of the activity. Students agreed that class discussions were a useful learning experience and 75% (77/102) said they would use the drug information references for other courses. The jigsaw technique was successful in engaging students in cooperative learning to improve critical thinking skills regarding drug information.

A Qualitative Analysis of the Turkish Gendarmerie Assignment Process

National Research Council Canada - National Science Library

Soylemez, Kadir

2005-01-01

...; this number increases to 43 million (65% of the population) in the summer months. This study is an organizational analysis of the current assignment process of the Turkish General Command of the Gendarmerie...

Multidimensional Screening as a Pharmacology Laboratory Experience.

Science.gov (United States)

Malone, Marvin H.; And Others

1979-01-01

A multidimensional pharmacodynamic screening experiment that addresses drug interaction is included in the pharmacology-toxicology laboratory experience of pharmacy students at the University of the Pacific. The student handout with directions for the procedure is reproduced, drug compounds tested are listed, and laboratory evaluation results are…

Anaerobic Digestion Analysis. Training Module 5.120.2.77.

Science.gov (United States)

Kirkwood Community Coll., Cedar Rapids, IA.

This document is an instructional module package prepared in objective form for use by an instructor familiar with alkalinity, volatile acids and carbon dioxide determinations for an anaerobic sludge digester. Included are objectives, instructor guides, student handouts and transparency masters. This module considers total and bicarbonate…

Selecting, Evaluating and Creating Policies for Computer-Based Resources in the Behavioral Sciences and Education.

Science.gov (United States)

Richardson, Linda B., Comp.; And Others

This collection includes four handouts: (1) "Selection Critria Considerations for Computer-Based Resources" (Linda B. Richardson); (2) "Software Collection Policies in Academic Libraries" (a 24-item bibliography, Jane W. Johnson); (3) "Circulation and Security of Software" (a 19-item bibliography, Sara Elizabeth Williams); and (4) "Bibliography of…

"Happy Days Are Here Again": A Left and Right Brain 4MAT Approach to Teaching Depression-Era Presidential Elections.

Science.gov (United States)

Cantu, D. Antonio

2001-01-01

Provides a lesson plan that focuses on the 1932, 1936, and 1940 presidential election campaigns. Illustrates the use of the left and right brain 4MAT teaching model that considers individual learning styles associated with right and left hemisphere dominance. Includes a bibliography and eight handouts. (CMK)

Young Teens (12-14 years of age)

Science.gov (United States)

... are a few tips to help protect your child: Make sure your teen knows about the importance of wearing seatbelts. Motor vehicle crashes are the ... your baby grows, including parenting tips. Patient/parent education handouts ... for your child’s regular check-up visit with your healthcare provider ...

Asset Mapping: A Course Assignment and Community Assessment

Science.gov (United States)

Crozier, Mary; Melchior, Florence

2013-01-01

Asset mapping is a relatively new data collection strategy to identify services, staff capacity, programs, resources, values, and other protective factors in a geographic area that can be juxtaposed to risk factors when initiating community planning. A substance abuse prevention course for undergraduates added an assignment of assessing community…

Linear Optimization of Frequency Spectrum Assignments Across System

Science.gov (United States)

2016-03-01

selection tools, frequency allocation, transmission optimization, electromagnetic maneuver warfare, electronic protection, assignment model 15. NUMBER ...Characteristics Modeled ...............................................................29 Table 10.   Antenna Systems Modeled , Number of Systems and...surveillance EW early warning GAMS general algebraic modeling system GHz gigahertz IDE integrated development environment ILP integer linear program

7 CFR 1425.24 - OMB control number assigned pursuant to Paperwork Reduction Act.

Science.gov (United States)

2010-01-01

...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS COOPERATIVE MARKETING ASSOCIATIONS § 1425.24 OMB control number assigned pursuant to Paperwork Reduction Act. The... Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have been assigned...

28 CFR 0.196 - Procedures for resolving disagreements concerning mail or case assignments.

Science.gov (United States)

2010-07-01

... concerning mail or case assignments. 0.196 Section 0.196 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Jurisdictional Disagreements § 0.196 Procedures for resolving... assigned, the disagreement, together with a statement of the view of the unit or units involved, shall be...

Joint Channel Assignment and Routing in Multiradio Multichannel Wireless Mesh Networks: Design Considerations and Approaches

Directory of Open Access Journals (Sweden)

Omar M. Zakaria

2016-01-01

Full Text Available Multiradio wireless mesh network is a promising architecture that improves the network capacity by exploiting multiple radio channels concurrently. Channel assignment and routing are underlying challenges in multiradio architectures since both determine the traffic distribution over links and channels. The interdependency between channel assignments and routing promotes toward the joint solutions for efficient configurations. This paper presents an in-depth review of the joint approaches of channel assignment and routing in multiradio wireless mesh networks. First, the key design issues, modeling, and approaches are identified and discussed. Second, existing algorithms for joint channel assignment and routing are presented and classified based on the channel assignment types. Furthermore, the set of reconfiguration algorithms to adapt the network traffic dynamics is also discussed. Finally, the paper presents some multiradio practical implementations and test-beds and points out the future research directions.

Selections from the ABC 2015 Annual Conference, Seattle, Washington: Pitching Fish and Innovative Oral and Written Business Communication Assignments

Science.gov (United States)

Whalen, D. Joel, Ed.

2016-01-01

This article, the first of a two-part series, presents teaching 10 innovations from the 2015 Association for Business Communication's 80th annual conference. The creative new assignments offered here include building listening skills by journaling, oral interpretation, positive message framing, storytelling, delivering bad news, persuasive…

Prediction and Assignment of Function for a Divergent N-succinyl Amino Acid Racemase

Energy Technology Data Exchange (ETDEWEB)

Song,L.; Kalyanaraman, C.; Fedorov, A.; Fedorov, E.; Glasner, M.; Brown, S.; Imker, H.; Babbitt, P.; Almo, S.; et al.

2007-01-01

The protein databases contain many proteins with unknown function. A computational approach for predicting ligand specificity that requires only the sequence of the unknown protein would be valuable for directing experiment-based assignment of function. We focused on a family of unknown proteins in the mechanistically diverse enolase superfamily and used two approaches to assign function: (i) enzymatic assays using libraries of potential substrates, and (ii) in silico docking of the same libraries using a homology model based on the most similar (35% sequence identity) characterized protein. The results matched closely; an experimentally determined structure confirmed the predicted structure of the substrate-liganded complex. We assigned the N-succinyl arginine/lysine racemase function to the family, correcting the annotation (L-Ala-D/L-Glu epimerase) based on the function of the most similar characterized homolog. These studies establish that ligand docking to a homology model can facilitate functional assignment of unknown proteins by restricting the identities of the possible substrates that must be experimentally tested.

A Multi-Objective Decision Support Model for the Turkish Armed Forces Personnel Assignment System

National Research Council Canada - National Science Library

Cimen, Zubeyir

2001-01-01

.... TAF wants to obtain maximum utilization of its personnel by assigning the right person to the right job at the right time, To accomplish this task, decision-makers and personnel assignment staff...

New assignment of 14N NQR spectral lines for tetrazoles derivatives

Science.gov (United States)

Mamadazizov, Sultonazar; Shelyapina, Marina G.; Kupriyanova, Galina S.; Mozzhukhin, George V.

2018-04-01

In recent years, considerable interest has been shown in the study of tetrazole derivatives, which attract attention as highly nitrogenous compounds for use as an isosteric substitutes for various functional groups that leads to creation of novel biologically active substances. NQR techniques, being sensitive to the local environment of 14N nuclei, provide great opportunities to study these new substances. To make investigation of complex compounds containing tetrazoles derivatives easier and more reliable a correctly assigned 14N NQR spectra of tetrazoles are required. Here we report on the results of our DFT B3LYP calculations of 14N NQR spectral parameters (quadrupole coupling constant Qcc and the asymmetry parameter of the electric field gradient η) for tetrazole, 5-aminotetrazole and 5-aminotetrazole monohydrate. It has been found that the commonly accepted assignment of the 14N NQR spectral lines for these molecules is incorrect. A new assignment for these molecules is proposed.

Evaluation of Dynamic Channel and Power Assignment for Cognitive Networks

Energy Technology Data Exchange (ETDEWEB)

Syed A. Ahmad; Umesh Shukla; Ryan E. Irwin; Luiz A. DaSilva; Allen B. MacKenzie

2011-03-01

In this paper, we develop a unifying optimization formulation to describe the Dynamic Channel and Power Assignment (DCPA) problem and evaluation method for comparing DCPA algorithms. DCPA refers to the allocation of transmit power and frequency channels to links in a cognitive network so as to maximize the total number of feasible links while minimizing the aggregate transmit power. We apply our evaluation method to five algorithms representative of DCPA used in literature. This comparison illustrates the tradeoffs between control modes (centralized versus distributed) and channel/power assignment techniques. We estimate the complexity of each algorithm. Through simulations, we evaluate the effectiveness of the algorithms in achieving feasible link allocations in the network, as well as their power efficiency. Our results indicate that, when few channels are available, the effectiveness of all algorithms is comparable and thus the one with smallest complexity should be selected. The Least Interfering Channel and Iterative Power Assignment (LICIPA) algorithm does not require cross-link gain information, has the overall lowest run time, and highest feasibility ratio of all the distributed algorithms; however, this comes at a cost of higher average power per link.

Application of Neutrosophic Set Theory in Generalized Assignment Problem

Directory of Open Access Journals (Sweden)

Supriya Kar

2015-09-01

Full Text Available This paper presents the application of Neutrosophic Set Theory (NST in solving Generalized Assignment Problem (GAP. GAP has been solved earlier under fuzzy environment. NST is a generalization of the concept of classical set, fuzzy set, interval-valued fuzzy set, intuitionistic fuzzy set. Elements of Neutrosophic set are characterized by a truth-membership function, falsity and also indeterminacy which is a more realistic way of expressing the parameters in real life problem. Here the elements of the cost matrix for the GAP are considered as neutrosophic elements which have not been considered earlier by any other author. The problem has been solved by evaluating score function matrix and then solving it by Extremum Difference Method (EDM [1] to get the optimal assignment. The method has been demonstrated by a suitable numerical example.

Using interviews to understand the assignment mechanism in a nonexperimental study: the case of eighth grade algebra.

Science.gov (United States)

Rickles, Jordan H

2011-10-01

Many inquiries regarding the causal effects of policies or programs are based on research designs where the treatment assignment process is unknown, and thus valid inferences depend on tenuous assumptions about the assignment mechanism. This article draws attention to the importance of understanding the assignment mechanism in policy and program evaluation studies, and illustrates how information collected through interviews can develop a richer understanding of the assignment mechanism. Focusing on the issue of student assignment to algebra in 8th grade, I show how a preliminary data collection effort aimed at understanding the assignment mechanism is particularly beneficial in multisite observational studies in education. The findings, based on ten interviews and administrative data from a large school district, draw attention to the often ignored heterogeneity in the assignment mechanism across schools. These findings likely extend beyond the current research project in question to related educational policy issues such as ability grouping, tracking, differential course taking, and curricular intensity, as well as other social programs in which the assignment mechanism can differ across sites.

Automated Negotiation for Resource Assignment in Wireless Surveillance Sensor Networks

Directory of Open Access Journals (Sweden)

Enrique de la Hoz

2015-11-01

Full Text Available Due to the low cost of CMOS IP-based cameras, wireless surveillance sensor networks have emerged as a new application of sensor networks able to monitor public or private areas or even country borders. Since these networks are bandwidth intensive and the radioelectric spectrum is limited, especially in unlicensed bands, it is mandatory to assign frequency channels in a smart manner. In this work, we propose the application of automated negotiation techniques for frequency assignment. Results show that these techniques are very suitable for the problem, being able to obtain the best solutions among the techniques with which we have compared them.

Evoked Feelings, Assigned Meanings and Constructed Knowledge Based on Mistakes

Directory of Open Access Journals (Sweden)

Luciane Guimarães Batistella Bianchini

2017-09-01

Full Text Available By means of Piaget's critical clinical method, the study investigated the meanings assigned to mistakes by four students in different activities and interactive situations. The research also analyzed the results of using self-regulatory situations in understanding mistakes initially committed by the students. Data collection instruments consisted of games, video recordings, diaries and interviews. Following intervention, the students were able to recognize their competence, establish positive interactions within the group, and avoid viewing mistakes as obstacles to learning. We concluded that the meanings assigned to mistakes depend on certain variables, among them feelings nurtured by the individuals about themselves, the other, and the object of knowledge.

29 CFR 785.37 - Home to work on special one-day assignment in another city.

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Home to work on special one-day assignment in another city... WORKED Application of Principles Traveltime § 785.37 Home to work on special one-day assignment in..., DC, with regular working hours from 9 a.m. to 5 p.m. may be given a special assignment in New York...

On the extreme points of the core of neighbour games and assignment games

NARCIS (Netherlands)

Hamers, H.J.M.; Klijn, F.; Solymosi, T.; Tijs, S.H.; Pere Villar, J.

1999-01-01

Neighbour games arise from certain matching or sequencing situations in which only some specific pairs of players can obtain a positive gain. As a consequence, neighbour games are as well assignment games as line graph restricted games. We will show that the intersection of the class of assignment

Effect on injuries of assigning shoes based on foot shape in air force basic training.

Science.gov (United States)

Knapik, Joseph J; Brosch, Lorie C; Venuto, Margaret; Swedler, David I; Bullock, Steven H; Gaines, Lorraine S; Murphy, Ryan J; Tchandja, Juste; Jones, Bruce H

2010-01-01

This study examined whether assigning running shoes based on the shape of the bottom of the foot (plantar surface) influenced injury risk in Air Force Basic Military Training (BMT) and examined risk factors for injury in BMT. Data were collected from BMT recruits during 2007; analysis took place during 2008. After foot examinations, recruits were randomly consigned to either an experimental group (E, n=1042 men, 375 women) or a control group (C, n=913 men, 346 women). Experimental group recruits were assigned motion control, stability, or cushioned shoes for plantar shapes indicative of low, medium, or high arches, respectively. Control group recruits received a stability shoe regardless of plantar shape. Injuries during BMT were determined from outpatient visits provided from the Defense Medical Surveillance System. Other injury risk factors (fitness, smoking, physical activity, prior injury, menstrual history, and demographics) were obtained from a questionnaire, existing databases, or BMT units. Multivariate Cox regression controlling for other risk factors showed little difference in injury risk between the groups among men (hazard ratio [E/C]=1.11, 95% CI=0.89-1.38) or women (hazard ratio [E/C]=1.20, 95% CI= 0.90-1.60). Independent injury risk factors among both men and women included low aerobic fitness and cigarette smoking. This prospective study demonstrated that assigning running shoes based on the shape of the plantar surface had little influence on injury risk in BMT even after controlling for other injury risk factors. Published by Elsevier Inc.

Calibration of a joint time assignment and mode choice model system

OpenAIRE

Greeven, Paulina; Jara-Diaz, Sergio R.; Munizaga, Marcela A.; Axhausen, Kay W.

2005-01-01

In this paper we report the results of applying a new microeconomic framework to model time assignment to activities, goods consumption and mode choice jointly (Jara-Díaz and Guevara, 2003; Jara-Díaz and Guerra, 2003) that identifies the links between these decisions and permits the calculation of all the components of the subjective value of time defined in the literature: the value of time as a resource, value of assigning time to a specific activity and the value of saving time in a specif...

Assignment about providing of substitute haptic interface for visually disabled persons

OpenAIRE

浅川, 貴史

2013-01-01

[Abstract] This paper is described about an assignment of haptic interface. We have made a proposal for a music baton system for visually disabled persons. The system is constituted by an acceleration sensor, a radio module, and a haptic interface device. We have carried out an experiment of comparing the visual and the haptic interface. The assignments are declared by the results that are rise-time of a motor and pre-motion. In the paper, we make a proposal for new method of the voltage cont...

Study on store-space assignment based on logistic AGV in e-commerce goods to person picking pattern

Science.gov (United States)

Xu, Lijuan; Zhu, Jie

2017-10-01

This paper studied on the store-space assignment based on logistic AGV in E-commerce goods to person picking pattern, and established the store-space assignment model based on the lowest picking cost, and design for store-space assignment algorithm after the cluster analysis based on similarity coefficient. And then through the example analysis, compared the picking cost between store-space assignment algorithm this paper design and according to item number and storage according to ABC classification allocation, and verified the effectiveness of the design of the store-space assignment algorithm.

Retaining a Resilient and Enduring Workforce: Examination of Duty/Position Rotational Assignments for Civilian Acquisition Positions

Science.gov (United States)

2015-04-12

civilian employees are composed primarily of “ Generation X” (people born roughly between 1965 and 1979) and Baby Boomers (people born roughly between...1946 and 1964). The employees replacing “ Generation X” and Baby Boomers are Millennials; “ninety-one percent of Millennials (born 1977–1997) expect to...distribution of the survey. Approximately 15% of the sample (including all General Schedule (GS) 14/15 government civilian employees assigned to Aberdeen

Assignment of absolute stereostructures through quantum mechanics electronic and vibrational circular dichroism calculations.

Science.gov (United States)

Dai, Peng; Jiang, Nan; Tan, Ren-Xiang

2016-01-01

Elucidation of absolute configuration of chiral molecules including structurally complex natural products remains a challenging problem in organic chemistry. A reliable method for assigning the absolute stereostructure is to combine the experimental circular dichroism (CD) techniques such as electronic and vibrational CD (ECD and VCD), with quantum mechanics (QM) ECD and VCD calculations. The traditional QM methods as well as their continuing developments make them more applicable with accuracy. Taking some chiral natural products with diverse conformations as examples, this review describes the basic concepts and new developments of QM approaches for ECD and VCD calculations in solution and solid states.

Threat evaluation and weapon assignment decision support: A ...

African Journals Online (AJOL)

... stands within the context of a ground based air defence system (GBADS) at the turn of the twenty first century. However, much of the contents of the paper maye generalized to military environments other than a GBADS one. Keywords: Threat evaluation, weapon assignment, decision support. ORiON Vol. 23 (2) 2007: pp.

Optimal resource assignment in workflows for maximizing cooperation

NARCIS (Netherlands)

Kumar, Akhil; Dijkman, R.M.; Song, Minseok; Daniel, Fl.; Wang, J.; Weber, B.

2013-01-01

A workflow is a team process since many actors work on various tasks to complete an instance. Resource management in such workflows deals with assignment of tasks to workers or actors. In team formation, it is necessary to ensure that members of a team are compatible with each other. When a workflow

Optimal Weight Assignment for a Chinese Signature File.

Science.gov (United States)

Liang, Tyne; And Others

1996-01-01

Investigates the performance of a character-based Chinese text retrieval scheme in which monogram keys and bigram keys are encoded into document signatures. Tests and verifies the theoretical predictions of the optimal weight assignments and the minimal false hit rate in experiments using a real Chinese corpus for disyllabic queries of different…

Diabetes HealthSense: Resources for Living Well

Medline Plus

Full Text Available ... and Kidney Disease 12 Diabetes is the leading cause of kidney disease. People living with diabetes offer tips on managing your diabetes and preventing kidney disease. Player Controls Use these controls to control the play back of videos. ... with Stress and Emotions AADE7 Self-Care Behaviors Handouts - Healthy Coping These handouts provide facts, tips, ...

Assigning probability distributions to input parameters of performance assessment models

Energy Technology Data Exchange (ETDEWEB)

Mishra, Srikanta [INTERA Inc., Austin, TX (United States)

2002-02-01

This study presents an overview of various approaches for assigning probability distributions to input parameters and/or future states of performance assessment models. Specifically,three broad approaches are discussed for developing input distributions: (a) fitting continuous distributions to data, (b) subjective assessment of probabilities, and (c) Bayesian updating of prior knowledge based on new information. The report begins with a summary of the nature of data and distributions, followed by a discussion of several common theoretical parametric models for characterizing distributions. Next, various techniques are presented for fitting continuous distributions to data. These include probability plotting, method of moments, maximum likelihood estimation and nonlinear least squares analysis. The techniques are demonstrated using data from a recent performance assessment study for the Yucca Mountain project. Goodness of fit techniques are also discussed, followed by an overview of how distribution fitting is accomplished in commercial software packages. The issue of subjective assessment of probabilities is dealt with in terms of the maximum entropy distribution selection approach, as well as some common rules for codifying informal expert judgment. Formal expert elicitation protocols are discussed next, and are based primarily on the guidance provided by the US NRC. The Bayesian framework for updating prior distributions (beliefs) when new information becomes available is discussed. A simple numerical approach is presented for facilitating practical applications of the Bayes theorem. Finally, a systematic framework for assigning distributions is presented: (a) for the situation where enough data are available to define an empirical CDF or fit a parametric model to the data, and (b) to deal with the situation where only a limited amount of information is available.

Assigning probability distributions to input parameters of performance assessment models

International Nuclear Information System (INIS)

Mishra, Srikanta

2002-02-01

This study presents an overview of various approaches for assigning probability distributions to input parameters and/or future states of performance assessment models. Specifically,three broad approaches are discussed for developing input distributions: (a) fitting continuous distributions to data, (b) subjective assessment of probabilities, and (c) Bayesian updating of prior knowledge based on new information. The report begins with a summary of the nature of data and distributions, followed by a discussion of several common theoretical parametric models for characterizing distributions. Next, various techniques are presented for fitting continuous distributions to data. These include probability plotting, method of moments, maximum likelihood estimation and nonlinear least squares analysis. The techniques are demonstrated using data from a recent performance assessment study for the Yucca Mountain project. Goodness of fit techniques are also discussed, followed by an overview of how distribution fitting is accomplished in commercial software packages. The issue of subjective assessment of probabilities is dealt with in terms of the maximum entropy distribution selection approach, as well as some common rules for codifying informal expert judgment. Formal expert elicitation protocols are discussed next, and are based primarily on the guidance provided by the US NRC. The Bayesian framework for updating prior distributions (beliefs) when new information becomes available is discussed. A simple numerical approach is presented for facilitating practical applications of the Bayes theorem. Finally, a systematic framework for assigning distributions is presented: (a) for the situation where enough data are available to define an empirical CDF or fit a parametric model to the data, and (b) to deal with the situation where only a limited amount of information is available

Sensor assignment to mission in AI-TECD

Science.gov (United States)

Ganger, Robert; de Mel, Geeth; Pham, Tien; Rudnicki, Ronald; Schreiber, Yonatan

2016-05-01

Sensor-mission assignment involves the allocation of sensors and other information-providing resources to missions in order to cover the information needs of the individual tasks within each mission. The importance of efficient and effective means to find appropriate resources for tasks is exacerbated in the coalition context where the operational environment is dynamic and a multitude of critically important tasks need to achieve their collective goals to meet the objectives of the coalition. The Sensor Assignment to Mission (SAM) framework—a research product of the International Technology Alliance in Network and Information Sciences (NIS-ITA) program—provided the first knowledge intensive resource selection approach for the sensor network domain so that contextual information could be used to effectively select resources for tasks in coalition environments. Recently, CUBRC, Inc. was tasked with operationalizing the SAM framework through the use of the I2WD Common Core Ontologies for the Communications-Electronics Research, Development and Engineering Center (CERDEC) sponsored Actionable Intelligence Technology Enabled Capabilities Demonstration (AI-TECD). The demonstration event took place at Fort Dix, New Jersey during July 2015, and this paper discusses the integration and the successful demonstration of the SAM framework within the AI-TECD, lessons learned, and its potential impact in future operations.

The phase-resolved photoacoustic method to indicate chemical assignments of paracetamol

Science.gov (United States)

Camilotti, J. G.; Somer, A.; Costa, G. F.; Ribeiro, M. A.; Bonardi, C.; Cruz, G. K.; Gómez, S. L.; Beltrame, F. L.; Medina, A. N.; Sato, F.; Astrath, N. G. C.; Novatski, A.

2014-03-01

In this work, the phase-resolved photoacoustic method was applied to provide specific information on the chemical assignments of paracetamol in the near-infrared region. Two broad bands, centered at 1370 and 1130 nm, were well-resolved using this method, making it possible to assign the peaks centered at 1398, 1355 and 1295 nm to a C-H combination from a CH3 structure and the peak at 1305 nm to a C-H combination from the aromatic ring. This information represents a new finding in chemical studies regarding this medicament.

Comparing two K-category assignments by a K-category correlation coefficient

DEFF Research Database (Denmark)

Gorodkin, Jan

2004-01-01

Predicted assignments of biological sequences are often evaluated by Matthews correlation coefficient. However, Matthews correlation coefficient applies only to cases where the assignments belong to two categories, and cases with more than two categories are often artificially forced into two...... categories by considering what belongs and what does not belong to one of the categories, leading to the loss of information. Here, an extended correlation coefficient that applies to K-categories is proposed, and this measure is shown to be highly applicable for evaluating prediction of RNA secondary...

Oral Hygiene. Instructor's Packet. Learning Activity Package.

Science.gov (United States)

Hime, Kirsten

This instructor's packet accompanies the learning activity package (LAP) on oral hygiene. Contents included in the packet are a time sheet, suggested uses for the LAP, an instruction sheet, final LAP reviews, a final LAP review answer key, suggested activities, additional resources (student handouts), student performance checklists for both…

Freedom of Religion and the Public Schools.

Science.gov (United States)

Williams, Mary Louise

1991-01-01

Presents activities for teaching high school students about the freedom of religion. Includes student handouts that explain basic constitutional principles and summarize leading U.S. Supreme Court cases concerning religious liberty. Encourages teachers to invite students to speculate on the future relationship of religion and public education. (SG)

"No Taxation without Representation:" A Simulation Activity.

Science.gov (United States)

Schur, Joan Brodsky

1992-01-01

Describes a simulation exercise designed to help students understand the objections of U.S. colonists to the Stamp Act and other taxes. Includes a sample handout, instructions for the teacher in carrying out the simulation, and questions to compare students' and colonists' about feelings being assessed fees unfairly. (DK)

Hollywood "Takes" on Domestic Subversion: The Role of Women in Cold War America.

Science.gov (United States)

Straughn, Victoria

2003-01-01

Discusses the role Hollywood and films had in defining the image of women in post-World War II in the United States. Focuses on the film, "Mildred Pierce," and offers a discussion of the content of this film. Includes a film based lesson plan and three accompanying handouts. (CMK)

Learn, Grow, Become. TSA Edition.

Science.gov (United States)

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This revised curriculum guide contains five units that are designed to help students develop an understanding of the mission of the Technology Student Association (TSA). Each unit follows a standard format that includes some or all of these basic components: performance objectives, suggested activities, handouts, information sheets, supplements,…

Gun Control: The Debate and Public Policy.

Science.gov (United States)

Watkins, Christine

1997-01-01

Provides an overview and background information on the debate over gun control, as well as several teaching ideas. Handouts include a list of related topics drawn from various disciplines (economics, U.S. history), seven arguments for and against gun control, and a set of policy evaluation guidelines. (MJP)

Synthetical analysis of the spin assignment for the superdeformed bands in A≅190 region

International Nuclear Information System (INIS)

Di Yaomin

2002-01-01

The spin assignment for the superdeformed bands of even-even nuclei in A ≅190 region is given by means of using the method of synthetical analysis. The I( I + 1) expression is used to fit the experimental data of the transition γ energies. In contrast to other procedure, the convergence process of the series expansions is put stress upon, whereas taking how many terms exactly in the expression does not emphasized. Moreover as well as the method of fitting the physical quantity, by use of these series expansions the moment of inertia of band heads is also calculated and then the systematics is used for the spin assignments. In practice, when the experimental data is abundant the systematics of the moment of inertia of band heads is more efficient than the method of fitting the physical quantity in the spin assignment. As for a few bands which spin assignment is difficult, the deviation from the typical rotational bands must be considered, which may be judged easily from the second class of moment of inertia of the bands. Finally the results of the spin assignment and the comparison with other literature are presented. These results should be more reliable

Ner protein of phage Mu: Assignments using {sup 13}C/{sup 15}N-labeled protein

Energy Technology Data Exchange (ETDEWEB)

Strzelecka, T.; Gronenborn, A.M.; Clore, G.M. [National Institutes of Health, Bethesda, MD (United States)

1994-12-01

The Ner protein is a small (74-amino acid) DNA-binding protein that regulates a switch between the lysogenic and lytic stages of phage Mu. It inhibits expression of the C repressor gene and down-regulates its own expression. Two-dimensional NMR experiments on uniformly {sup 15}N-labeled protein provided most of the backbone and some of the sidechain proton assignments. The secondary structure determination using two-dimensional NOESY experiments showed that Ner consists of five {alpha}-helices. However, because most of the sidechain protons could not be assigned, the full structure was not determined. Using uniformly {sup 13}C/{sup 15}N-labeled Ner and a set of three-dimensional experiments, we were able to assign all of the backbone and 98% of the sidechain protons. In particular, the CBCANH and CBCA(CO)NH experiments were used to sequentially assign the C{alpha} and C{beta} resonances; the HCCH-CTOCSY and HCCH-COSY were used to assign sidechain carbon and proton resonances.

A singular value sensitivity approach to robust eigenstructure assignment

DEFF Research Database (Denmark)

Søgaard-Andersen, Per; Trostmann, Erik; Conrad, Finn

1986-01-01

A design technique for improving the feedback properties of multivariable state feedback systems designed using eigenstructure assignment is presented. Based on a singular value analysis of the feedback properties a design parameter adjustment procedure is outlined. This procedure allows...

Developing Team Skills through a Collaborative Writing Assignment

Science.gov (United States)

Thomas, Theda Ann

2014-01-01

Employers want students who are able to work effectively as members of a team, and expect universities to develop this ability in their graduates. This paper proposes a framework for a collaborative writing assignment that specifically develops students' ability to work in teams. The framework has been tested using two iterations of an action…

Careerism, Committee Assignments and the Electoral Connection

OpenAIRE

Katz, Jonathan N.; Sala, Brian R.

1996-01-01

Most scholars agree that members of Congress are strongly motivated by their desire for reelection. This assumption implies that members of Congress adopt institutions, rules, and norms of behavior in part to serve their electoral interests. Direct tests of the electoral connection are rare, however, because significant, exogenous changes in the electoral environment are difficult to identify. We develop and test an electoral rationale for the norm of committee assignment "property rights...

A fuzzy-based particle swarm optimisation approach for task assignment in home healthcare

Directory of Open Access Journals (Sweden)

Mutingi, Michael

2014-11-01

Full Text Available Home healthcare (HHC organisations provide coordinated healthcare services to patients at their homes. Motivated by the ever-increasing need for home-based care, the assignment of tasks to available healthcare staff is a common and complex problem in homecare organisations. Designing high quality task schedules is critical for improving worker morale, job satisfaction, service efficiency, service quality, and competitiveness over the long term. The desire is to provide high quality task assignment schedules that satisfy the patient, the care worker, and the management. This translates to maximising schedule fairness in terms of workload assignments, avoiding task time window violation, and meeting management goals as much as possible. However, in practice, these desires are often subjective as they involve imprecise human perceptions. This paper develops a fuzzy multi-criteria particle swarm optimisation (FPSO approach for task assignment in a home healthcare setting in a fuzzy environment. The proposed approach uses a fuzzy evaluation method from a multi-criteria point of view. Results from illustrative computational experiments show that the approach is promising.

Dynamic activity-travel assignment in multi-state supernetworks with road and location capacity constraints

NARCIS (Netherlands)

Liu, P.; Liao, F.; Huang, H.; Timmermans, H.J.P.

2016-01-01

A unified framework coupling activity-based modelling and dynamic traffic assignment has recently been proposed. It formulates dynamic activity-travel assignment (DATA) in multi-state supernetworks as a dynamic user equilibrium. Choices of departure time, route, mode, activity sequence, and

A Simple Method for Solving Fully Intuitionistic Fuzzy Real Life Assignment Problem

OpenAIRE

Senthil Kumar, P.; Jahir Hussain, R.

2016-01-01

In solving real life assignment problem we often face the state of uncertainty as well as hesitation due to various uncontrollable factors. To deal with uncertainty and hesitation many authors have suggested the intuitionistic fuzzy representations for the data. So, in this paper, the authors consider the assignment problem having uncertainty and hesitation in cost/time/profit. They formulate the problem and utilize triangular intuitionistic fuzzy numbers (TIFNs) to deal with uncertainty and ...

The Kinetics of Chirality Assignment in Catalytic Single Walled Carbon Nanotube Growth

OpenAIRE

Xu, Ziwei; Yan, Tianying; Ding, Feng

2014-01-01

Chirality-selected single-walled carbon nanotubes (SWCNTs) ensure a great potential of building ~1 nm sized electronics. However, the reliable method for chirality-selected SWCNT is still pending. Here we present a theoretical study on the SWCNT's chirality assignment and control during the catalytic growth. This study reveals that the chirality of a SWCNT is determined by the kinetic incorporation of the pentagon formation during SWCNT nucleation. Therefore, chirality is randomly assigned on...

Protect Heterogeneous Environment Distributed Computing from Malicious Code Assignment

Directory of Open Access Journals (Sweden)

V. S. Gorbatov

2011-09-01

Full Text Available The paper describes the practical implementation of the protection system of heterogeneous environment distributed computing from malicious code for the assignment. A choice of technologies, development of data structures, performance evaluation of the implemented system security are conducted.

NEW CRITERIA FOR ASSIGNING WASTE CONTAINING TECH-NOGENIC RADIONUCLIDES TO THE RADIOACTIVE WASTE

Directory of Open Access Journals (Sweden)

I. K. Romanovich

2010-01-01

Full Text Available The article contains detailed description of criteria for assigning of liquid and gaseous industrial waste containing technogenicradionuclides to the radioactive waste, presented in the new Basic Sanitary Rulesof Radiation Safety (OSPORB-99/2010. The analysisof shortcomings and discrepancies of the previously used in Russia system of criteria for assigning waste to the radioactive waste is given.

The (digital) natives are restless: designing and implementing an interactive digital media assignment.

Science.gov (United States)

Voge, Catherine; Hirvela, Kari; Jarzemsky, Paula

2012-01-01

To create an opportunity for students to connect with the Quality and Safety Education for Nurses competencies and demonstrate learning via knowledge transference, the authors piloted a digital media assignment. Students worked in small groups to create an unfolding patient care scenario with embedded decision points, using presentation software. The authors discuss the assignment and its outcomes.

More Districts Factoring Poverty into Student-Assignment Plans

Science.gov (United States)

Zehr, Mary Ann

2010-01-01

A growing number of school districts are trying to break up concentrations of poverty on their campuses by taking students' family income into consideration in school assignments. Some of the districts replaced race with socioeconomic status as a determining indicator after the U.S. Supreme Court ruled in 2007 that using race as the primary factor…

The role of high-level calculations in the assignment of the Q-band spectra of chlorophyll

Energy Technology Data Exchange (ETDEWEB)

Reimers, Jeffrey R. [School of Physics and Materials Science, The University of Technology, Sydney NSW (Australia); Cai, Zheng-Li [School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, Brisbane QLD4001 (Australia); Kobayashi, Rika [Australian National University Supercomputer Facility, Mills Rd, Canberra, ACT 0200 (Australia); Rätsep, Margus [Institute of Physics, University of Tartu, Riia 142, 51014 Tartu (Estonia); Freiberg, Arvi [Institute of Physics, University of Tartu, Riia 142, 51014 Tartu, Estonia and Institute of Molecular and Cell Biology, University of Tartu, Riia 23, 51010 Tartu (Estonia); Krausz, Elmars [Research School of Chemistry, The Australian National University, Canberra 2601 (Australia)

2014-10-06

We recently established a novel assignment of the visible absorption spectrum of chlorophyll-a that sees the two components Q{sub x} and Q{sub y} of the low-energy Q band as being intrinsically mixed by non-adiabatic coupling. This ended 50 years debate as to the nature of the Q bands, with prior discussion poised only in the language of the Born-Oppenheimer and Condon approximations. The new assignment presents significant ramifications for exciton transport and quantum coherence effects in photosystems. Results from state of the art electronic structure calculations have always been used to justify assignments, but quantitative inaccuracies and systematic failures have historically limited usefulness. We examine the role of CAM-B3LYP time-dependent density-functional theory (TD-DFT) and Symmetry Adapted Cluster-Configuration Interaction (SAC-CI) calculations in first showing that all previous assignments were untenable, in justifying the new assignment, in making some extraordinary predictions that were vindicated by the new assignment, and in then identifying small but significant anomalies in the extensive experimental data record.

Optimal assignment methods in three-form planned missing data designs for longitudinal panel studies

NARCIS (Netherlands)

Jorgensen, T.D.; Rhemtulla, M.; Schoemann, A.; McPherson, B.; Wu, W.; Little, T.D.

2014-01-01

Planned missing designs are becoming increasingly popular, but because there is no consensus on how to implement them in longitudinal research, we simulated longitudinal data to distinguish between strategies of assigning items to forms and of assigning forms to participants across measurement

Evolution of Various Library Instruction Strategies: Using Student Feedback to Create and Enhance Online Active Learning Assignments

Directory of Open Access Journals (Sweden)

Marcie Lynne Jacklin

2013-06-01

Full Text Available This case study traces the evolution of library assignments for biological science students from paper-based workbooks in a blended (hands-on workshop to blended learning workshops using online assignments to online active learning modules which are stand-alone without any face-to-face instruction. As the assignments evolved to adapt to online learning supporting materials in the form of PDFs (portable document format, screen captures and screencasting were embedded into the questions as teaching moments to replace face-to-face instruction. Many aspects of the evolution of the assignment were based on student feedback from evaluations, input from senior lab demonstrators and teaching assistants, and statistical analysis of the students’ performance on the assignment. Advantages and disadvantages of paper-based and online assignments are discussed. An important factor for successful online learning may be the ability to get assistance.

Analyzing the multiple-target-multiple-agent scenario using optimal assignment algorithms

Science.gov (United States)

Kwok, Kwan S.; Driessen, Brian J.; Phillips, Cynthia A.; Tovey, Craig A.

1997-09-01

This work considers the problem of maximum utilization of a set of mobile robots with limited sensor-range capabilities and limited travel distances. The robots are initially in random positions. A set of robots properly guards or covers a region if every point within the region is within the effective sensor range of at least one vehicle. We wish to move the vehicles into surveillance positions so as to guard or cover a region, while minimizing the maximum distance traveled by any vehicle. This problem can be formulated as an assignment problem, in which we must optimally decide which robot to assign to which slot of a desired matrix of grid points. The cost function is the maximum distance traveled by any robot. Assignment problems can be solved very efficiently. Solution times for one hundred robots took only seconds on a silicon graphics crimson workstation. The initial positions of all the robots can be sampled by a central base station and their newly assigned positions communicated back to the robots. Alternatively, the robots can establish their own coordinate system with the origin fixed at one of the robots and orientation determined by the compass bearing of another robot relative to this robot. This paper presents example solutions to the multiple-target-multiple-agent scenario using a matching algorithm. Two separate cases with one hundred agents in each were analyzed using this method. We have found these mobile robot problems to be a very interesting application of network optimization methods, and we expect this to be a fruitful area for future research.

Analyzing the multiple-target-multiple-agent scenario using optimal assignment algorithms

International Nuclear Information System (INIS)

Kwok, K.S.; Driessen, B.J.; Phillips, C.A.; Tovey, C.A.

1997-01-01

This work considers the problem of maximum utilization of a set of mobile robots with limited sensor-range capabilities and limited travel distances. The robots are initially in random positions. A set of robots properly guards or covers a region if every point within the region is within the effective sensor range of at least one vehicle. The authors wish to move the vehicles into surveillance positions so as to guard or cover a region, while minimizing the maximum distance traveled by any vehicle. This problem can be formulated as an assignment problem, in which they must optimally decide which robot to assign to which slot of a desired matrix of grid points. The cost function is the maximum distance traveled by any robot. Assignment problems can be solved very efficiently. Solutions times for one hundred robots took only seconds on a Silicon Graphics Crimson workstation. The initial positions of all the robots can be sampled by a central base station and their newly assigned positions communicated back to the robots. Alternatively, the robots can establish their own coordinate system with the origin fixed at one of the robots and orientation determined by the compass bearing of another robot relative to this robot. This paper presents example solutions to the multiple-target-multiple-agent scenario using a matching algorithm. Two separate cases with one hundred agents in each were analyzed using this method. They have found these mobile robot problems to be a very interesting application of network optimization methods, and they expect this to be a fruitful area for future research

A multiobjective approach towards weapon assignment in a ground ...

African Journals Online (AJOL)

A typical ground-based air defence (GBAD) environment comprises defended assets on the ground which require protection from enemy aircraft entering the defended airspace. ... of computerised threat evaluation and weapon assignment (TEWA) decision support systems (DSSs) within the context of a GBAD system.

Impact of reflective writing assignments on dental students' views of cultural competence and diversity.

Science.gov (United States)

Isaac, Carol; Behar-Horenstein, Linda; Lee, Barbara; Catalanotto, Frank

2015-03-01

To respond to widespread disparities in access to oral health care, the Institute of Medicine, the Commission on Dental Accreditation (CODA), and the U.S. surgeon general have stressed that prospective dentists should become culturally competent, socially responsible practitioners. The aim of this study was to examine linguistic differences in dental students' reflective writing assignments before and after interviewing an individual who was culturally different from themselves. The authors analyzed 160 documents from 80 first-year dental students at the University of Florida in 2012. This cohort consisted of 36 male (45%) and 44 female (55%) students; 26 (32%) were from underrepresented minority (URM) groups and 54 (68%) were identified as white non-minority. Text analysis software identified word counts, categories, frequencies, and contexts. Significantly positive differences occurred for interviews between assignments 1 and 2 (p=0.005 to pcultural diversity. Differences were observed for Factor 1 ("important others' influence") between assignments (p<0.001), assignments by interview categories (p=0.033), and URM/majority participants by assignments by interview category (p=0.018). Factor 4 ("my social world in relation to others") was statistically different between assignments for URM/majority participants (p=0.019). Factor 5 ("wrong because") was statistically different for gender (p=0.041), suggesting that males may have experienced a rebound effect from stereotype suppression. The findings suggest that the use of reflective writing and interviews affected the students' awareness of how important others had influenced their lives and attitudes and facilitated their questioning preconceived assumptions. Reactions to coursework focusing on social and personal domains warrant further investigation.

D. W. Griffith's Controversial Film, "The Birth of a Nation."

Science.gov (United States)

Pitcher, Conrad

1999-01-01

Presents a lesson plan that enables students to investigate race relations during the Progressive Era by analyzing D. W. Griffith's "The Birth of a Nation" and the controversy surrounding the release of the film. Explores the pros and cons of using motion pictures as teaching tool. Includes two student handouts. (CMK)

ADHD in the Schools: Assessment and Intervention Strategies. Second Edition

Science.gov (United States)

DuPaul, George J.; Stoner, Gary

2004-01-01

This popular reference and text provides essential guidance for school-based professionals meeting the challenges of ADHD at any grade level. Comprehensive and practical, the book includes several reproducible assessment tools and handouts. A team-based approach to intervention is emphasized in chapters offering research-based guidelines for: (1)…

CNN Newsroom Classroom Guides, October 2000.

Science.gov (United States)

Turner Educational Services, Inc., Newtown, PA.

These classroom guides, designed to accompany the daily CNN (Cable News Network) Newsroom broadcasts for the month of October 2000, provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Top stories include: Chinese authorities detain Falun Gong protesters on Tiananmen Square…

Alkalinity Analysis. Training Module 5.220.2.77.

Science.gov (United States)

Bonte, John L.; Davidson, Arnold C.

This document is an instructional module package prepared in objective form for use by an instructor familiar with the acid-base titrimetric procedure for determining the hydroxide, carbonate and bicarbonate alkalinity of a water sample. Included are objectives, an instructor guide, student handouts and transparency masters. A video tape is also…

Turbidity. Training Module 5.240.2.77.

Science.gov (United States)

Bonte, John L.; Davidson, Arnold C.

This document is an instructional module package prepared in objective form for use by an instructor familiar with candle turbidimeter and the nephelometric method of turbidity analysis. Included are objectives, an instructor guide, student handout, and transparency masters. A video tape is also available from the author. This module considers use…

Teaching about Tort Law--My Actions, My Actions, Somebody Got Hurt!

Science.gov (United States)

Rose, Stephen A.

1997-01-01

Presents a lesson plan that uses cases to teach students about three types of torts: intentional wrongs, negligence, and strict liability. Torts are wrongful actions (not involving a breech of contract) that may result in a civic action. Includes lesson procedures, objectives, and student handouts on torts and negligence cases. (MJP)

Censorship during the Depression: The Banning of "You and Machines."

Science.gov (United States)

Barry, Arlene L.

2001-01-01

Provides background information on the Civilian Conservation Corps (CCC) focusing on the educational programs for the CCC. Presents a lesson on the censorship of the booklet "You and Machines" from the CCC programs. Includes excerpts from "You and Machines," copies of newspaper articles about the booklet, and a student handout.…

CNN Newsroom Classroom Guides. September 1-30, 1994.

Science.gov (United States)

Cable News Network, Atlanta, GA.

These classroom guides for the daily CNN (Cable News Network) Newsroom broadcasts for the month of August provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics covered by the guides include: (1) truce in Northern Ireland, school censorship, scientific method, burial…

Artificial intelligence applied to assigned merchandise location in retail sales systems

Directory of Open Access Journals (Sweden)

Cruz-Domínguez, O.

2016-05-01

Full Text Available This paper presents an option for improving the process of assigning storage locations for merchandise in a warehouse. A disadvantage of policies in the literature is that the merchandise is assigned allocation only according to the volume of sales and the rotation it presents. However, in some cases it is necessary to deal with other aspects such as family group membership, the physical characteristics of the products, and their sales pattern to design an integral policy. This paper presents an alternative to the afore- mentioned process using Flexsim®, artificial neural networks, and genetic algorithms.

Learning Gains from a Recurring "Teach and Question" Homework Assignment in a General Biology Course: Using Reciprocal Peer Tutoring Outside Class.

Science.gov (United States)

Bailey, E G; Baek, D; Meiling, J; Morris, C; Nelson, N; Rice, N S; Rose, S; Stockdale, P

2018-06-01

Providing students with one-on-one interaction with instructors is a big challenge in large courses. One solution is to have students interact with their peers during class. Reciprocal peer tutoring (RPT) is a more involved interaction that requires peers to alternate the roles of "teacher" and "student." Theoretically, advantages for peer tutoring include the verbalization and questioning of information and the scaffolded exploration of material through social and cognitive interaction. Studies on RPT vary in their execution, but most require elaborate planning and take up valuable class time. We tested the effectiveness of a "teach and question" (TQ) assignment that required student pairs to engage in RPT regularly outside class. A quasi-experimental design was implemented: one section of a general biology course completed TQ assignments, while another section completed a substitute assignment requiring individuals to review course material. The TQ section outperformed the other section by ∼6% on exams. Session recordings were coded to investigate correlation between TQ quality and student performance. Asking more questions was the characteristic that best predicted exam performance, and this was more predictive than most aspects of the course. We propose the TQ as an easy assignment to implement with large performance gains.

Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion

International Nuclear Information System (INIS)

Habenstein, Birgit; Wasmer, Christian; Bousset, Luc; Sourigues, Yannick; Schütz, Anne; Loquet, Antoine; Meier, Beat H.; Melki, Ronald; Böckmann, Anja

2011-01-01

We present the de novo resonance assignments for the crystalline 33 kDa C-terminal domain of the Ure2 prion using an optimized set of five 3D solid-state NMR spectra. We obtained, using a single uniformly 13 C, 15 N labeled protein sample, sequential chemical-shift information for 74% of the N, Cα, Cβ triples, and for 80% of further side-chain resonances for these spin systems. We describe the procedures and protocols devised, and discuss possibilities and limitations of the assignment of this largest protein assigned today by solid-state NMR, and for which no solution-state NMR shifts were available. A comparison of the NMR chemical shifts with crystallographic data reveals that regions with high crystallographic B-factors are particularly difficult to assign. While the secondary structure elements derived from the chemical shift data correspond mainly to those present in the X-ray crystal structure, we detect an additional helical element and structural variability in the protein crystal, most probably originating from the different molecules in the asymmetric unit, with the observation of doubled resonances in several parts, including entire stretches, of the protein. Our results provide the point of departure towards an atomic-resolution structural analysis of the C-terminal Ure2p domain in the context of the full-length prion fibrils.

Extensive de novo solid-state NMR assignments of the 33 kDa C-terminal domain of the Ure2 prion

Energy Technology Data Exchange (ETDEWEB)

Habenstein, Birgit [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France); Wasmer, Christian [Harvard Medical School (United States); Bousset, Luc; Sourigues, Yannick [UPR 3082 CNRS, Laboratoire d' Enzymologie et Biochimie Structurales (France); Schuetz, Anne [ETH Zurich, Physical Chemistry (Switzerland); Loquet, Antoine [Max Planck Institute for Biophysical Chemistry (Germany); Meier, Beat H., E-mail: beme@ethz.ch [ETH Zurich, Physical Chemistry (Switzerland); Melki, Ronald, E-mail: melki@lebs.cnrs-gif.fr [UPR 3082 CNRS, Laboratoire d' Enzymologie et Biochimie Structurales (France); Boeckmann, Anja, E-mail: a.bockmann@ibcp.fr [UMR 5086 CNRS/Universite de Lyon 1, Institut de Biologie et Chimie des Proteines (France)

2011-11-15

We present the de novo resonance assignments for the crystalline 33 kDa C-terminal domain of the Ure2 prion using an optimized set of five 3D solid-state NMR spectra. We obtained, using a single uniformly {sup 13}C, {sup 15}N labeled protein sample, sequential chemical-shift information for 74% of the N, C{alpha}, C{beta} triples, and for 80% of further side-chain resonances for these spin systems. We describe the procedures and protocols devised, and discuss possibilities and limitations of the assignment of this largest protein assigned today by solid-state NMR, and for which no solution-state NMR shifts were available. A comparison of the NMR chemical shifts with crystallographic data reveals that regions with high crystallographic B-factors are particularly difficult to assign. While the secondary structure elements derived from the chemical shift data correspond mainly to those present in the X-ray crystal structure, we detect an additional helical element and structural variability in the protein crystal, most probably originating from the different molecules in the asymmetric unit, with the observation of doubled resonances in several parts, including entire stretches, of the protein. Our results provide the point of departure towards an atomic-resolution structural analysis of the C-terminal Ure2p domain in the context of the full-length prion fibrils.

Complete sequence-specific 1H NMR assignments for human insulin

International Nuclear Information System (INIS)

Kline, A.D.; Justice, R.M. Jr.

1990-01-01

Solvent conditions where human insulin could be studied by high-resolution NMR were determined. Both low pH and addition of acetonitrile were required to overcome the protein's self-association and to obtain useful spectra. Two hundred eighty-six 1 H resonances were located and assigned to specific sites on the protein by using two-dimensional NMR methods. The presence and position of numerous d NN sequential NOE's indicate that the insulin conformation seen in crystallographic studies is largely retained under these solution conditions. Slowly exchanging protons were observed for seven backbone amide protons and were assigned to positions A15 and A16 and to positions B15-B19. These amides all occur within helical regions of the protein

75 FR 66267 - Delegation of Authority and Assignment of Responsibility; Secretary's Order 6-2010

Science.gov (United States)

2010-10-27

... Business Act, as amended, 15 U.S.C. 644(n). (14) Social Security Act of 1935, as amended, Title III-Grants... Part V Department of Labor Delegation of Authority and Assignment of Responsibility; Secretary's... of Responsibility; Secretary's Order 6-2010 Subject: Delegation of Authority and Assignment of...

Revisit assignments of the new excited Ω{sub c} states with QCD sum rules

Energy Technology Data Exchange (ETDEWEB)

Wang, Zhi-Gang; Wei, Xing-Ning; Yan, Ze-Hui [North China Electric Power University, Department of Physics, Baoding (China)

2017-12-15

In this article, we distinguish the contributions of the positive parity and negative parity Ω{sub c} states, study the masses and pole residues of the 1S, 1P, 2S and 2P Ω{sub c} states with the spin J = (1)/(2) and (3)/(2) using the QCD sum rules in a consistent way, and we revisit the assignments of the new narrow excited Ω{sub c}{sup 0} states. The predictions support assigning Ω{sub c}(3000) to the 1P Ω{sub c} state with J{sup P} = (1)/(2){sup -}, assigning Ω{sub c}(3090) to the 1P Ω{sub c} state with J{sup P} = (3)/(2){sup -} or the 2S Ω{sub c} state with J{sup P} = (1)/(2){sup +}, and assigning Ω{sub c}(3119) to the 2S Ω{sub c} state with J{sup P} = (3)/(2){sup +}. (orig.)

RESCUE: An artificial neural network tool for the NMR spectral assignment of proteins

International Nuclear Information System (INIS)

Pons, J.L.; Delsuc, M.A.

1999-01-01

The assignment of the 1 H spectrum of a protein or a polypeptide is the prerequisite for advanced NMR studies. We present here an assignment tool based on the artificial neural network technology, which determines the type of the amino acid from the chemical shift values observed in the 1 H spectrum. Two artificial neural networks have been trained and extensively tested against a non-redundant subset of the BMRB chemical shift data bank [Seavey, B.R. et al. (1991) J. Biomol. NMR, 1, 217-236]. The most promising of the two accomplishes the analysis in two steps, grouping related amino acids together. It presents a mean rate of success above 80% on the test set. The second network tested separates down to the single amino acid; it presents a mean rate of success of 63%. This tool has been used to assist the manual assignment of peptides and proteins and can also be used as a block in an automated approach to assignment. The program has been called RESCUE and is made publicly available at the following URL: http://www.infobiosud.univ-montp1.fr/rescue

Due date assignment procedures with dynamically updated coefficients for multi-level assembly job shops

NARCIS (Netherlands)

Adam, N.R.; Bertrand, J.W.M.; Morehead, D.C.; Surkis, J.

1993-01-01

This paper presents a study of due date assignment procedures in job shop environments where multi-level assembly jobs are processed and due dates are internally assigned. Most of the reported studies in the literature have focused on string type jobs. We propose a dynamic update approach (which

Mini-Journals: Incorporating Inquiry, Quantitative Skills and Writing into Homework Assignments for Geochemistry and Planetary Science

Science.gov (United States)

Whittington, A. G.; Speck, A.; Witzig, S.

2011-12-01

As part of an NSF-funded project, "CUES: Connecting Undergraduates to the Enterprise of Science," new inquiry-based homework materials were developed for two upper-level classes at the University of Missouri: Geochemistry (required for Geology majors, fulfills the computing requirement by having 50% of the grade come from five spreadsheet-based homework assignments), and Solar System Science (open to seniors and graduate students, co-taught and cross-listed between Geology and Physics & Astronomy). Inquiry involves activities where the learner engages in scientifically oriented questions, gives priority to evidence in responding to questions, formulates explanations from evidence, connects explanations to scientific knowledge, and communicates and justifies explanations. We engage students in inquiry-based learning by presenting homework exercises as "mini-journal" articles that follow the format of a scientific journal article, including a title, authors, abstract, introduction, methods, results, discussion and citations to peer-reviewed literature. The mini-journal provides a scaffold and serves as a springboard for students to develop and carry out their own follow-up investigation. They then present their findings in the form of their own mini-journal. Mini-journals replace traditional homework problem sets with a format that more directly reflects and encourages scientific practice. Students are engaged in inquiry-based homework which encompass doing, thinking, and communicating, while the mini-journal allows the instructor to contain lines of inquiry within the limits posed by available resources. In the examples we present, research is conducted via spreadsheet modeling, where the students develop their own spreadsheets. Example assignments from Geochemistry include "Trace Element Partitioning During Mantle Melting and MORB Crystallization" and "Isotopic Investigations of Crustal Evolution in the Midcontinent US". The key differences between the old and new

Total synthesis and stereochemical assignment of the salicylate antitumor macrolide lobatamide C(1).

Science.gov (United States)

Shen, Ruichao; Lin, Cheng Ting; Porco, John A

2002-05-22

The total synthesis and stereochemical assignment of the potent antitumor macrolide lobatamide C is reported. The synthesis involves Cu(I)-mediated enamide formation and Na(2)CO(3)-mediated esterification of a beta-hydroxy acid and a salicylate cyanomethyl ester. Macrolactonization was accomplished using a Mitsunobu protocol. The stereochemical assignment of lobatamide C was achieved by Mosher ester analysis and comparison with prepared stereoisomers.

Automated error-tolerant macromolecular structure determination from multidimensional nuclear Overhauser enhancement spectra and chemical shift assignments: improved robustness and performance of the PASD algorithm

Energy Technology Data Exchange (ETDEWEB)

Kuszewski, John J.; Thottungal, Robin Augustine [National Institutes of Health, Imaging Sciences Laboratory, Center for Information Technology (United States); Clore, G. Marius [National Institutes of Health, Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases (United States)], E-mail: mariusc@mail.nih.gov; Schwieters, Charles D. [National Institutes of Health, Imaging Sciences Laboratory, Center for Information Technology (United States)], E-mail: Charles.Schwieters@nih.gov

2008-08-15

We report substantial improvements to the previously introduced automated NOE assignment and structure determination protocol known as PASD (Kuszewski et al. (2004) J Am Chem Soc 26:6258-6273). The improved protocol includes extensive analysis of input spectral data to create a low-resolution contact map of residues expected to be close in space. This map is used to obtain reasonable initial guesses of NOE assignment likelihoods which are refined during subsequent structure calculations. Information in the contact map about which residues are predicted to not be close in space is applied via conservative repulsive distance restraints which are used in early phases of the structure calculations. In comparison with the previous protocol, the new protocol requires significantly less computation time. We show results of running the new PASD protocol on six proteins and demonstrate that useful assignment and structural information is extracted on proteins of more than 220 residues. We show that useful assignment information can be obtained even in the case in which a unique structure cannot be determined.

A novel strategy for NMR resonance assignment and protein structure determination

International Nuclear Information System (INIS)

Lemak, Alexander; Gutmanas, Aleksandras; Chitayat, Seth; Karra, Murthy; Farès, Christophe; Sunnerhagen, Maria; Arrowsmith, Cheryl H.

2011-01-01

The quality of protein structures determined by nuclear magnetic resonance (NMR) spectroscopy is contingent on the number and quality of experimentally-derived resonance assignments, distance and angular restraints. Two key features of protein NMR data have posed challenges for the routine and automated structure determination of small to medium sized proteins; (1) spectral resolution – especially of crowded nuclear Overhauser effect spectroscopy (NOESY) spectra, and (2) the reliance on a continuous network of weak scalar couplings as part of most common assignment protocols. In order to facilitate NMR structure determination, we developed a semi-automated strategy that utilizes non-uniform sampling (NUS) and multidimensional decomposition (MDD) for optimal data collection and processing of selected, high resolution multidimensional NMR experiments, combined it with an ABACUS protocol for sequential and side chain resonance assignments, and streamlined this procedure to execute structure and refinement calculations in CYANA and CNS, respectively. Two graphical user interfaces (GUIs) were developed to facilitate efficient analysis and compilation of the data and to guide automated structure determination. This integrated method was implemented and refined on over 30 high quality structures of proteins ranging from 5.5 to 16.5 kDa in size.

A DISTRIBUTIVE EDUCATION GUIDE TO AVAILABLE LITERATURE.

Science.gov (United States)

BARNETT, ANNA MAE; HEPHNER, THOMAS A.

HANDOUTS, REPRINTS, PAMPHLETS, AND BROCHURES AVAILABLE FROM THE DISTRIBUTIVE EDUCATION MATERIALS LABORATORY AT THE OHIO STATE UNIVERSITY ARE LISTED. THESE ARE FOR USE IN THE CLASSROOM, OR IN DEVELOPING OR PROMOTING DISTRIBUTIVE EDUCATION PROGRAMS. THE MANUAL INCLUDES (1) A LIST OF MATERIALS FOR SALE WITH FORM NUMBER, BRIEF DESCRIPTION, AND PRICE,…

CNN Newsroom Classroom Guides. June 1-30, 1994.

Science.gov (United States)

Cable News Network, Atlanta, GA.

These classroom guides for the daily CNN (Cable News Network) Newsroom broadcasts for the month of June provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics covered by the guides include: (1) Congressman Dan Rostenkowski, D-Day, cars and Singapore, Rodney King civil…

Setting the Record Straight. The Truth About Fad Diets.

Science.gov (United States)

Wheat Foods Council, Parker, CO.

The Setting the Record Straight information packet presents facts to set the record straight about nutrition and debunk fad diets. The kit features materials designed to communicate the importance of balanced eating. Materials include: a time line of fad diets; four reproducible fad diet book review handouts that show the misleading claims rampant…

A Tractor or an Automobile? A 1920s Farm Family Faces a Decision.

Science.gov (United States)

Kunze, Joel P.

1991-01-01

Outlines a lesson plan in which students role play a 1920s farm family deciding whether to buy an automobile or a tractor. Other students act as automobile and tractor sales groups. Explains how the lesson illuminates relationships between technological advance and social history. Includes handouts identifying benefits of purchasing cars or…

Procedimientos Comunes de Operacion Para Juntas Responsabilidades y Derechos del Presidente, Vice Presidente, Secretaria, y Miembros (Standard Procedures of Operation for Meetings, Rights, and Responsibilities of the President, Vice President, Secretary, and Members).

Science.gov (United States)

Gonzalez, Ramon

Of use to Parent Advisory Committees, this Spanish-English handout briefly describes the standard procedures used to conduct meetings and outlines the duties of committee officers and members. The pamphlet describes the standard order of business at a meeting, including calling a meeting to order, roll call, minutes, reports, unfinished and new…

Life on a Farm during the Great Depression.

Science.gov (United States)

Musbach, Joan W.

2001-01-01

Presents a lesson plan for eighth-grade students where they learn about the Great Depression by studying rural life. Explains that the students explore farm records from June and December 1935 after reading an excerpt about rural life in the 1930s. Includes copies of the ledgers, photographs, and student handouts. (CMK)

Forestry. Teacher Edition.

Science.gov (United States)

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum is designed to provide training in skills used by technicians and foresters throughout the world who plant, care for, and harvest trees. It contains 16 units. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities, handouts, information sheets,…

THE ANALYSIS OF INTERFERENCE ON WRITING ASSIGNMENTS OF THE MIDWIFERY STUDENTS

Directory of Open Access Journals (Sweden)

I G. A. Agung Sintha Satwika

2013-11-01

Full Text Available This research aims at investigating and analyzing the interference which occurred in English text made by the students of Akademi Kebidanan Bali Wisnu Dharma. The data of this writing were collected from the writing assignment of the students at Akademi Kebidanan Bali Wisnu Dharma, which was divided into six groups. The data were obtained by reading intensively those texts and followed by applying the note taking technique. The result of this study indicates that the interference occurred on those writing assignments in terms of semantics level, spelling, copula, syntax, literal translation, redundancy, over generalization, and interference in terms of English pronoun.

Imprint of DESI fiber assignment on the anisotropic power spectrum of emission line galaxies

Energy Technology Data Exchange (ETDEWEB)

Pinol, Lucas [Département de Physique, École Normale Supérieure, Paris (France); Cahn, Robert N. [Lawrence Berkeley National Laboratory, Berkeley, California (United States); Hand, Nick [Department of Astronomy, University of California, Berkeley, California (United States); Seljak, Uroš; White, Martin, E-mail: lucas.pinol@ens.fr, E-mail: rncahn@lbl.gov, E-mail: nhand@berkeley.edu, E-mail: useljak@berkeley.edu, E-mail: mwhite@berkeley.edu [Department of Physics, University of California, Berkeley, California (United States)

2017-04-01

The Dark Energy Spectroscopic Instrument (DESI), a multiplexed fiber-fed spectrograph, is a Stage-IV ground-based dark energy experiment aiming to measure redshifts for 29 million Emission-Line Galaxies (ELG), 4 million Luminous Red Galaxies (LRG), and 2 million Quasi-Stellar Objects (QSO). The survey design includes a pattern of tiling on the sky, the locations of the fiber positioners in the focal plane of the telescope, and an observation strategy determined by a fiber assignment algorithm that optimizes the allocation of fibers to targets. This strategy allows a given region to be covered on average five times for a five-year survey, with a typical variation of about 1.5 about the mean, which imprints a spatially-dependent pattern on the galaxy clustering. We investigate the systematic effects of the fiber assignment coverage on the anisotropic galaxy clustering of ELGs and show that, in the absence of any corrections, it leads to discrepancies of order ten percent on large scales for the power spectrum multipoles. We introduce a method where objects in a random catalog are assigned a coverage, and the mean density is separately computed for each coverage factor. We show that this method reduces, but does not eliminate the effect. We next investigate the angular dependence of the contaminated signal, arguing that it is mostly localized to purely transverse modes. We demonstrate that the cleanest way to remove the contaminating signal is to perform an analysis of the anisotropic power spectrum P ( k ,μ) and remove the lowest μ bin, leaving μ > 0 modes accurate at the few-percent level. Here, μ is the cosine of the angle between the line-of-sight and the direction of k-vector . We also investigate two alternative definitions of the random catalog and show that they are comparable but less effective than the coverage randoms method.

An automated framework for NMR resonance assignment through simultaneous slice picking and spin system forming

KAUST Repository

Abbas, Ahmed; Guo, Xianrong; Jing, Bingyi; Gao, Xin

2014-01-01

positives and negatives impair the performance of resonance assignment methods. One of the main reasons for this problem is that the computational research community often considers peak picking and resonance assignment to be two separate problems, whereas