WorldWideScience

Sample records for include characterization setting

  1. IGSA: Individual Gene Sets Analysis, including Enrichment and Clustering.

    Science.gov (United States)

    Wu, Lingxiang; Chen, Xiujie; Zhang, Denan; Zhang, Wubing; Liu, Lei; Ma, Hongzhe; Yang, Jingbo; Xie, Hongbo; Liu, Bo; Jin, Qing

    2016-01-01

    Analysis of gene sets has been widely applied in various high-throughput biological studies. One weakness in the traditional methods is that they neglect the heterogeneity of genes expressions in samples which may lead to the omission of some specific and important gene sets. It is also difficult for them to reflect the severities of disease and provide expression profiles of gene sets for individuals. We developed an application software called IGSA that leverages a powerful analytical capacity in gene sets enrichment and samples clustering. IGSA calculates gene sets expression scores for each sample and takes an accumulating clustering strategy to let the samples gather into the set according to the progress of disease from mild to severe. We focus on gastric, pancreatic and ovarian cancer data sets for the performance of IGSA. We also compared the results of IGSA in KEGG pathways enrichment with David, GSEA, SPIA, ssGSEA and analyzed the results of IGSA clustering and different similarity measurement methods. Notably, IGSA is proved to be more sensitive and specific in finding significant pathways, and can indicate related changes in pathways with the severity of disease. In addition, IGSA provides with significant gene sets profile for each sample.

  2. Including Students with Severe Disabilities in General Education Settings.

    Science.gov (United States)

    Wisniewski, Lech; Alper, Sandra

    1994-01-01

    This paper presents five systematic phases for bringing about successful regular education inclusion of students with severe disabilities. Phases include develop networks within the community, assess school and community resources, review strategies for integration, install strategies that lead to integration, and develop a system of feedback and…

  3. Pulmonary nodule characterization, including computer analysis and quantitative features.

    Science.gov (United States)

    Bartholmai, Brian J; Koo, Chi Wan; Johnson, Geoffrey B; White, Darin B; Raghunath, Sushravya M; Rajagopalan, Srinivasan; Moynagh, Michael R; Lindell, Rebecca M; Hartman, Thomas E

    2015-03-01

    Pulmonary nodules are commonly detected in computed tomography (CT) chest screening of a high-risk population. The specific visual or quantitative features on CT or other modalities can be used to characterize the likelihood that a nodule is benign or malignant. Visual features on CT such as size, attenuation, location, morphology, edge characteristics, and other distinctive "signs" can be highly suggestive of a specific diagnosis and, in general, be used to determine the probability that a specific nodule is benign or malignant. Change in size, attenuation, and morphology on serial follow-up CT, or features on other modalities such as nuclear medicine studies or MRI, can also contribute to the characterization of lung nodules. Imaging analytics can objectively and reproducibly quantify nodule features on CT, nuclear medicine, and magnetic resonance imaging. Some quantitative techniques show great promise in helping to differentiate benign from malignant lesions or to stratify the risk of aggressive versus indolent neoplasm. In this article, we (1) summarize the visual characteristics, descriptors, and signs that may be helpful in management of nodules identified on screening CT, (2) discuss current quantitative and multimodality techniques that aid in the differentiation of nodules, and (3) highlight the power, pitfalls, and limitations of these various techniques.

  4. International Spinal Cord Injury Core Data Set (version 2.0)-including standardization of reporting

    NARCIS (Netherlands)

    Biering-Sorensen, F.; DeVivo, M. J.; Charlifue, S.; Chen, Y.; New, P. W.; Noonan, V.; Post, M. W. M.; Vogel, L.

    Study design: The study design includes expert opinion, feedback, revisions and final consensus. Objectives: The objective of the study was to present the new knowledge obtained since the International Spinal Cord Injury (SCI) Core Data Set (Version 1.0) published in 2006, and describe the

  5. International Spinal Cord Injury Core Data Set (version 2.0)-including standardization of reporting

    NARCIS (Netherlands)

    Biering-Sørensen, F; DeVivo, M J; Charlifue, Susan; Chen, Y; New, P.W.; Noonan, V.; Post, M W M; Vogel, L.

    STUDY DESIGN: The study design includes expert opinion, feedback, revisions and final consensus. OBJECTIVES: The objective of the study was to present the new knowledge obtained since the International Spinal Cord Injury (SCI) Core Data Set (Version 1.0) published in 2006, and describe the

  6. Pseudodynamic Source Characterization for Strike-Slip Faulting Including Stress Heterogeneity and Super-Shear Ruptures

    KAUST Repository

    Mena, B.

    2012-08-08

    Reliable ground‐motion prediction for future earthquakes depends on the ability to simulate realistic earthquake source models. Though dynamic rupture calculations have recently become more popular, they are still computationally demanding. An alternative is to invoke the framework of pseudodynamic (PD) source characterizations that use simple relationships between kinematic and dynamic source parameters to build physically self‐consistent kinematic models. Based on the PD approach of Guatteri et al. (2004), we propose new relationships for PD models for moderate‐to‐large strike‐slip earthquakes that include local supershear rupture speed due to stress heterogeneities. We conduct dynamic rupture simulations using stochastic initial stress distributions to generate a suite of source models in the magnitude Mw 6–8. This set of models shows that local supershear rupture speed prevails for all earthquake sizes, and that the local rise‐time distribution is not controlled by the overall fault geometry, but rather by local stress changes on the faults. Based on these findings, we derive a new set of relations for the proposed PD source characterization that accounts for earthquake size, buried and surface ruptures, and includes local rise‐time variations and supershear rupture speed. By applying the proposed PD source characterization to several well‐recorded past earthquakes, we verify that significant improvements in fitting synthetic ground motion to observed ones is achieved when comparing our new approach with the model of Guatteri et al. (2004). The proposed PD methodology can be implemented into ground‐motion simulation tools for more physically reliable prediction of shaking in future earthquakes.

  7. A characterization of linearly repetitive cut and project sets

    Science.gov (United States)

    Haynes, Alan; Koivusalo, Henna; Walton, James

    2018-02-01

    For the development of a mathematical theory which can be used to rigorously investigate physical properties of quasicrystals, it is necessary to understand regularity of patterns in special classes of aperiodic point sets in Euclidean space. In one dimension, prototypical mathematical models for quasicrystals are provided by Sturmian sequences and by point sets generated by substitution rules. Regularity properties of such sets are well understood, thanks mostly to well known results by Morse and Hedlund, and physicists have used this understanding to study one dimensional random Schrödinger operators and lattice gas models. A key fact which plays an important role in these problems is the existence of a subadditive ergodic theorem, which is guaranteed when the corresponding point set is linearly repetitive. In this paper we extend the one-dimensional model to cut and project sets, which generalize Sturmian sequences in higher dimensions, and which are frequently used in mathematical and physical literature as models for higher dimensional quasicrystals. By using a combination of algebraic, geometric, and dynamical techniques, together with input from higher dimensional Diophantine approximation, we give a complete characterization of all linearly repetitive cut and project sets with cubical windows. We also prove that these are precisely the collection of such sets which satisfy subadditive ergodic theorems. The results are explicit enough to allow us to apply them to known classical models, and to construct linearly repetitive cut and project sets in all pairs of dimensions and codimensions in which they exist. Research supported by EPSRC grants EP/L001462, EP/J00149X, EP/M023540. HK also gratefully acknowledges the support of the Osk. Huttunen foundation.

  8. Floating point only SIMD instruction set architecture including compare, select, Boolean, and alignment operations

    Science.gov (United States)

    Gschwind, Michael K [Chappaqua, NY

    2011-03-01

    Mechanisms for implementing a floating point only single instruction multiple data instruction set architecture are provided. A processor is provided that comprises an issue unit, an execution unit coupled to the issue unit, and a vector register file coupled to the execution unit. The execution unit has logic that implements a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA). The floating point vector registers of the vector register file store both scalar and floating point values as vectors having a plurality of vector elements. The processor may be part of a data processing system.

  9. A HPMT based set-up to characterize scintillating crystals

    International Nuclear Information System (INIS)

    D'Ambrosio, C.; Ercoli, C.; Jaaskelainen, S.; Lecoeur, G.; Leutz, H.; Loos, R.; Piedigrossi, D.; Puertolas, D.; Rosso, E.; Schomaker, R.

    1999-01-01

    We have developed a fully automatic measurement set-up, capable of measuring light yields arising from scintillating crystals in a linear range of about four orders of magnitude. The photodetector is a hybrid photomultiplier tube specially developed to optimize linear range and photon detection. Crystal and photodetector are temperature controlled by a closed water circuit, as this is essential when measuring low light yield scintillating crystals with a marked temperature dependence of their light yield. Gamma sources can be placed either on top or on the side of the crystal. In this latter case, the source can be automatically moved by a computer-controlled step motor to provide a uniformity profile of the light yield along the crystal. Tagged and not-tagged operation modes are possible. The whole set-up is computer-controlled in an effort to provide fast and reliable measurements, to characterize many crystals per day. This is important for the quality control of the lead tungstate crystals that will be applied in the electromagnetic calorimeter of the CMS-detector at the LHC at CERN. (author)

  10. A HPMT based set-up to characterize scintillating crystals

    Energy Technology Data Exchange (ETDEWEB)

    D' Ambrosio, C.; Ercoli, C.; Jaaskelainen, S.; Lecoeur, G.; Leutz, H.; Loos, R.; Piedigrossi, D.; Puertolas, D.; Rosso, E.; Schomaker, R

    1999-09-21

    We have developed a fully automatic measurement set-up, capable of measuring light yields arising from scintillating crystals in a linear range of about four orders of magnitude. The photodetector is a hybrid photomultiplier tube specially developed to optimize linear range and photon detection. Crystal and photodetector are temperature controlled by a closed water circuit, as this is essential when measuring low light yield scintillating crystals with a marked temperature dependence of their light yield. Gamma sources can be placed either on top or on the side of the crystal. In this latter case, the source can be automatically moved by a computer-controlled step motor to provide a uniformity profile of the light yield along the crystal. Tagged and not-tagged operation modes are possible. The whole set-up is computer-controlled in an effort to provide fast and reliable measurements, to characterize many crystals per day. This is important for the quality control of the lead tungstate crystals that will be applied in the electromagnetic calorimeter of the CMS-detector at the LHC at CERN. (author)

  11. Semantical Characterizations and Complexity of Equivalences in Answer Set Programming

    OpenAIRE

    Eiter, Thomas; Fink, Michael; Woltran, Stefan

    2005-01-01

    In recent research on non-monotonic logic programming, repeatedly strong equivalence of logic programs P and Q has been considered, which holds if the programs P union R and Q union R have the same answer sets for any other program R. This property strengthens equivalence of P and Q with respect to answer sets (which is the particular case for R is the empty set), and has its applications in program optimization, verification, and modular logic programming. In this paper, we consider more lib...

  12. Characterization of sucrose-negative Pasteurella multocida variants, including isolates from large-cat bite wounds

    DEFF Research Database (Denmark)

    Christensen, Henrik Grimmig; Bisgaard, Magne; Angen, Øystein

    2005-01-01

    To validate the identification of Pasteurella multocida-like bacteria negative for acid formation from sucrose, including isolates from bite wounds caused by large cats, 17 strains were phenotypically and genotypically characterized. Phylogenetic analysis of partially sequenced rpoB and infB genes...... showed the monophyly of the strains characterized and the reference strains of P. multocida. The sucrose-negative strains formed two groups, one related to reference strains of P. multocida and the other related to a separate species-like group (taxon 45 of Bisgaard). DNA-DNA hybridization further...... and the reference strains of P. multocida. Two strains isolated from leopard bite wounds were related to the type strain of P. dagmatis; however, they represented a new taxon (taxon 46 of Bisgaard), in accordance with their distinct phenotypic and genotypic identifications. The present study documents that sucrose-negative...

  13. Experimental validation of control strategies for a microgrid test facility including a storage system and renewable generation sets

    DEFF Research Database (Denmark)

    Baccino, Francesco; Marinelli, Mattia; Silvestro, Federico

    2012-01-01

    The paper is aimed at describing and validating some control strategies in the SYSLAB experimental test facility characterized by the presence of a low voltage network with a 15 kW-190 kWh Vanadium Redox Flow battery system and a 11 kW wind turbine. The generation set is connected to the local...... network and is fully controllable by the SCADA system. The control strategies, implemented on a local pc interfaced to the SCADA, are realized in Matlab-Simulink. The main purpose is to control the charge/discharge action of the storage system in order to present at the point of common coupling...... the desired power or energy profiles....

  14. Characterizing omega-limit sets which are closed orbits

    Science.gov (United States)

    Bautista, S.; Morales, C.

    Let X be a vector field in a compact n-manifold M, n⩾2. Given Σ⊂M we say that q∈M satisfies (P) Σ if the closure of the positive orbit of X through q does not intersect Σ, but, however, there is an open interval I with q as a boundary point such that every positive orbit through I intersects Σ. Among those q having saddle-type hyperbolic omega-limit set ω(q) the ones with ω(q) being a closed orbit satisfy (P) Σ for some closed subset Σ. The converse is true for n=2 but not for n⩾4. Here we prove the converse for n=3. Moreover, we prove for n=3 that if ω(q) is a singular-hyperbolic set [C. Morales, M. Pacifico, E. Pujals, On C robust singular transitive sets for three-dimensional flows, C. R. Acad. Sci. Paris Sér. I 26 (1998) 81-86], [C. Morales, M. Pacifico, E. Pujals, Robust transitive singular sets for 3-flows are partially hyperbolic attractors or repellers, Ann. of Math. (2) 160 (2) (2004) 375-432], then ω(q) is a closed orbit if and only if q satisfies (P) Σ for some Σ closed. This result improves [S. Bautista, Sobre conjuntos hiperbólicos-singulares (On singular-hyperbolic sets), thesis Uiversidade Federal do Rio de Janeiro, 2005 (in Portuguese)] and [C. Morales, M. Pacifico, Mixing attractors for 3-flows, Nonlinearity 14 (2001) 359-378].

  15. Tracer experiment data sets for the verification of local and meso-scale atmospheric dispersion models including topographic effects

    International Nuclear Information System (INIS)

    Sartori, E.; Schuler, W.

    1992-01-01

    Software and data for nuclear energy applications are acquired, tested and distributed by several information centres; in particular, relevant computer codes are distributed internationally by the OECD/NEA Data Bank (France) and by ESTSC and EPIC/RSIC (United States). This activity is coordinated among the centres and is extended outside the OECD area through an arrangement with the IAEA. This article proposes more specifically a scheme for acquiring, storing and distributing atmospheric tracer experiment data (ATE) required for verification of atmospheric dispersion models especially the most advanced ones including topographic effects and specific to the local and meso-scale. These well documented data sets will form a valuable complement to the set of atmospheric dispersion computer codes distributed internationally. Modellers will be able to gain confidence in the predictive power of their models or to verify their modelling skills. (au)

  16. Characterizing and predicting rates of delirium across general hospital settings.

    Science.gov (United States)

    McCoy, Thomas H; Hart, Kamber L; Perlis, Roy H

    2017-05-01

    To better understand variation in reported rates of delirium, this study characterized delirium occurrence rate by department of service and primary admitting diagnosis. Nine consecutive years (2005-2013) of general hospital admissions (N=831,348) were identified across two academic medical centers using electronic health records. The primary admitting diagnosis and the treating clinical department were used to calculate occurrence rates of a previously published delirium definition composed of billing codes and natural language processing of discharge summaries. Delirium rates varied significantly across both admitting diagnosis group (X 2 10 =12786, pdelirium (86/109764; 0.08%) and neurological admissions the greatest (2851/25450; 11.2%). Although the rate of delirium varied across the two hospitals the relative rates within departments (r=0.96, pdelirium varies significantly across admitting diagnosis and hospital department. Both admitting diagnosis and department of care are even stronger predictors of risk than age; as such, simple risk stratification may offer avenues for targeted prevention and treatment efforts. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Synthesis and characterization of polyphosphazene electrolytes including cyclic ether side groups

    Science.gov (United States)

    Fiedler, Carsten; Luerssen, Bjoern; Lucht, Brett; Janek, Juergen

    2018-04-01

    This paper presents the synthesis and detailed characterization of two polyphosphazene based polymers, including different cyclic ether side groups. The final polymers were obtained by a well-known method employing a living cationic polymerization and subsequent nucleophilic substitution. The synthesized polymers Poly [(1,3-dioxane-5-oxy) (1,3-dioxolane-4-methoxy)phosphazene] (DOPP) and Poly[bis(2-Tetrahydro-3-furanoxy)phosphazene] (THFPP) were mixed with varied amounts of lithium bis(trifluoromethane)sulfonamide (LiTFSI) and the interactions between the salt and the polymer chains were studied by Fourier transform infrared (FT-IR) and differential scanning calorimetry (DSC) measurements. Electrochemical characterization was performed by electrochemical impedance spectroscopy (EIS) and direct current polarization in the temperature range of 20-60 °C. These measurements were utilized to calculate the lithium transference number (t+), the lithium conductivity (σ) and its activation energy in order to elucidate the lithium transport behavior. Relatively high lithium transference numbers of 0.6 (DOPP) and 0.7 (THFPP) at 60 °C are found and reveal maximum lithium conductivities of 2.8·10-6 Sṡcm-1 and 9.0·10-7 Sṡcm-1 for DOPP and THFPP at 60 °C, respectively.

  18. Preface to the Viewpoint Set: Nanostructured metals - Advances in processing, characterization and application

    DEFF Research Database (Denmark)

    Huang, Xiaoxu

    2009-01-01

    with increasingly finer structures in order to improve properties and sustainability. The structural scale of interest in such materials is therefore reduced to the nanometer range, which means that characterization and modeling of nanostructured metals now address an audience including not only physicists...... and materials scientists but also technologists and engineers. The present Viewpoint Set therefore covers metallic materials with a structural scale ranging from micrometer to nanometer in dimensions and focuses on processing techniques such as plastic deformation and phase transformations. As a result......The theme of two viewpoint sets has been nanostructured metals: one in 2003 on “Mechanical properties of fully dense nanocrystalline metals” (Scripta Materialia 2003;49:625–680) and one in 2004 on “Metals and alloys with a structural scale from the micrometer to the atomic dimensions” (Scripta...

  19. Survey indicated that core outcome set development is increasingly including patients, being conducted internationally and using Delphi surveys.

    Science.gov (United States)

    Biggane, Alice M; Brading, Lucy; Ravaud, Philippe; Young, Bridget; Williamson, Paula R

    2018-02-17

    There are numerous challenges in including patients in a core outcome set (COS) study, these can vary depending on the patient group. This study describes current efforts to include patients in the development of COS, with the aim of identifying areas for further improvement and study. Using the COMET database, corresponding authors of COS projects registered or published from 1 January 2013 to 2 February 2017 were invited via a personalised email to participate in a short online survey. The survey and emails were constructed to maximise the response rate by following the academic literature on enhancing survey responses. Personalised reminder emails were sent to non-responders. This survey explored the frequency of patient input in COS studies, who was involved, what methods were used and whether or not the COS development was international. One hundred and ninety-two COS developers were sent the survey. Responses were collected from 21 February 2017 until 7 May 2017. One hundred and forty-six unique developers responded, yielding a 76% response rate and data in relation to 195 unique COSs (as some developers had worked on multiple COSs). Of focus here are their responses regarding 162 COSs at the published, completed or ongoing stages of development. Inclusion of patient participants was indicated in 87% (141/162) of COSs in the published completed or ongoing stages and over 94% (65/69) of ongoing COS projects. Nearly half (65/135) of COSs included patient participants from two or more countries and 22% (30/135) included patient participants from five or more countries. The Delphi survey was reported as being used singularly or in combination with other methods in 85% (119/140) of projects. Almost a quarter (16/65) of ongoing studies reported using a combination of qualitative interviews, Delphi survey and consensus meeting. These findings indicated that the Delphi survey is the most popular method of facilitating patient participation, while the combination of

  20. Model Selection and Evaluation Based on Emerging Infectious Disease Data Sets including A/H1N1 and Ebola

    Directory of Open Access Journals (Sweden)

    Wendi Liu

    2015-01-01

    Full Text Available The aim of the present study is to apply simple ODE models in the area of modeling the spread of emerging infectious diseases and show the importance of model selection in estimating parameters, the basic reproduction number, turning point, and final size. To quantify the plausibility of each model, given the data and the set of four models including Logistic, Gompertz, Rosenzweg, and Richards models, the Bayes factors are calculated and the precise estimates of the best fitted model parameters and key epidemic characteristics have been obtained. In particular, for Ebola the basic reproduction numbers are 1.3522 (95% CI (1.3506, 1.3537, 1.2101 (95% CI (1.2084, 1.2119, 3.0234 (95% CI (2.6063, 3.4881, and 1.9018 (95% CI (1.8565, 1.9478, the turning points are November 7,November 17, October 2, and November 3, 2014, and the final sizes until December 2015 are 25794 (95% CI (25630, 25958, 3916 (95% CI (3865, 3967, 9886 (95% CI (9740, 10031, and 12633 (95% CI (12515, 12750 for West Africa, Guinea, Liberia, and Sierra Leone, respectively. The main results confirm that model selection is crucial in evaluating and predicting the important quantities describing the emerging infectious diseases, and arbitrarily picking a model without any consideration of alternatives is problematic.

  1. Apology in the criminal justice setting: evidence for including apology as an additional component in the legal system.

    Science.gov (United States)

    Petrucci, Carrie J

    2002-01-01

    The criminal justice system has reached unprecedented scope in the United States, with over 6.4 million people under some type of supervision. Remedies that have the potential to reduce this number are continually being sought. This article analyzes an innovative strategy currently being reconsidered in criminal justice: the apology. Despite a legal system that only sporadically acknowledges it, evidence for the use of apology is supported by social science research, current criminal justice theories, case law, and empirical studies. Social psychological, sociological and socio-legal studies pinpoint the elements and function of apology, what makes apologies effective, and concerns about apology if it were implemented in the criminal justice system. Theoretical evidence is examined (including restorative justice, therapeutic jurisprudence, crime, shame, and reintegration) to explore the process of apology in the criminal justice context. Attribution theory and social conduct theory are used to explain the apology process specifically for victims and offenders. A brief examination of case law reveals that though apology has no formal place in criminal law, it has surfaced recently under the federal sentencing guidelines. Finally, empirical evidence in criminal justice settings reveals that offenders want to apologize and victims desire an apology. Moreover, by directly addressing the harmful act, apology may be the link to reduced recidivism for offenders, as well as empowerment for victims. This evidence combined suggests that apology is worthy of further study as a potentially valuable addition to the criminal justice process. Copyright 2002 John Wiley & Sons, Ltd.

  2. Ferroelectric crystals for photonic applications including nanoscale fabrication and characterization techniques

    CERN Document Server

    Ferraro, Pietro; De Natale, Paolo

    2015-01-01

    This book details the latest achievements in ferroelectric domain engineering and characterization at micro- and nano-scale dimensions and periods. It combines basic research of magnetic materials with device and production orientation.

  3. Characterization of mammographic masses based on level set segmentation with new image features and patient information

    International Nuclear Information System (INIS)

    Shi Jiazheng; Sahiner, Berkman; Chan Heangping; Ge Jun; Hadjiiski, Lubomir; Helvie, Mark A.; Nees, Alexis; Wu Yita; Wei Jun; Zhou Chuan; Zhang Yiheng; Cui Jing

    2008-01-01

    Computer-aided diagnosis (CAD) for characterization of mammographic masses as malignant or benign has the potential to assist radiologists in reducing the biopsy rate without increasing false negatives. The purpose of this study was to develop an automated method for mammographic mass segmentation and explore new image based features in combination with patient information in order to improve the performance of mass characterization. The authors' previous CAD system, which used the active contour segmentation, and morphological, textural, and spiculation features, has achieved promising results in mass characterization. The new CAD system is based on the level set method and includes two new types of image features related to the presence of microcalcifications with the mass and abruptness of the mass margin, and patient age. A linear discriminant analysis (LDA) classifier with stepwise feature selection was used to merge the extracted features into a classification score. The classification accuracy was evaluated using the area under the receiver operating characteristic curve. The authors' primary data set consisted of 427 biopsy-proven masses (200 malignant and 227 benign) in 909 regions of interest (ROIs) (451 malignant and 458 benign) from multiple mammographic views. Leave-one-case-out resampling was used for training and testing. The new CAD system based on the level set segmentation and the new mammographic feature space achieved a view-based A z value of 0.83±0.01. The improvement compared to the previous CAD system was statistically significant (p=0.02). When patient age was included in the new CAD system, view-based and case-based A z values were 0.85±0.01 and 0.87±0.02, respectively. The study also demonstrated the consistency of the newly developed CAD system by evaluating the statistics of the weights of the LDA classifiers in leave-one-case-out classification. Finally, an independent test on the publicly available digital database for screening

  4. Ferroelectric crystals for photonic applications including nanoscale fabrication and characterization techniques

    CERN Document Server

    Grilli, Simonetta

    2008-01-01

    This book deals with the latest achievements in the field of ferroelectric domain engineering and characterization at micron- and nano-scale dimensions and periods. The book collects the results obtained in the last years by world scientific leaders in the field, thus providing a valid and unique overview of the state of the art and also a view to future applications of those engineered materials in the field of photonics.

  5. Developing a set of consensus indicators to support maternity service quality improvement: using Core Outcome Set methodology including a Delphi process.

    Science.gov (United States)

    Bunch, K J; Allin, B; Jolly, M; Hardie, T; Knight, M

    2018-05-16

    To develop a core metric set to monitor the quality of maternity care. Delphi process followed by a face-to-face consensus meeting. English maternity units. Three representative expert panels: service designers, providers and users. Maternity care metrics judged important by participants. Participants were asked to complete a two-phase Delphi process, scoring metrics from existing local maternity dashboards. A consensus meeting discussed the results and re-scored the metrics. In all, 125 distinct metrics across six domains were identified from existing dashboards. Following the consensus meeting, 14 metrics met the inclusion criteria for the final core set: smoking rate at booking; rate of birth without intervention; caesarean section delivery rate in Robson group 1 women; caesarean section delivery rate in Robson group 2 women; caesarean section delivery rate in Robson group 5 women; third- and fourth-degree tear rate among women delivering vaginally; rate of postpartum haemorrhage of ≥1500 ml; rate of successful vaginal birth after a single previous caesarean section; smoking rate at delivery; proportion of babies born at term with an Apgar score improvement. Achieving consensus on core metrics for monitoring the quality of maternity care. © 2018 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists.

  6. Characterization results and Markov chain Monte Carlo algorithms including exact simulation for some spatial point processes

    DEFF Research Database (Denmark)

    Häggström, Olle; Lieshout, Marie-Colette van; Møller, Jesper

    1999-01-01

    The area-interaction process and the continuum random-cluster model are characterized in terms of certain functional forms of their respective conditional intensities. In certain cases, these two point process models can be derived from a bivariate point process model which in many respects...... is simpler to analyse and simulate. Using this correspondence we devise a two-component Gibbs sampler, which can be used for fast and exact simulation by extending the recent ideas of Propp and Wilson. We further introduce a Swendsen-Wang type algorithm. The relevance of the results within spatial statistics...

  7. Isolation and Characterization of Vaccine Candidate Genes Including CSP and MSP1 in Plasmodium yoelii.

    Science.gov (United States)

    Kim, Seon-Hee; Bae, Young-An; Seoh, Ju-Young; Yang, Hyun-Jong

    2017-06-01

    Malaria is an infectious disease affecting humans, which is transmitted by the bite of Anopheles mosquitoes harboring sporozoites of parasitic protozoans belonging to the genus Plasmodium . Despite past achievements to control the protozoan disease, malaria still remains a significant health threat up to now. In this study, we cloned and characterized the full-unit Plasmodium yoelii genes encoding merozoite surface protein 1 (MSP1), circumsporozoite protein (CSP), and Duffy-binding protein (DBP), each of which can be applied for investigations to obtain potent protective vaccines in the rodent malaria model, due to their specific expression patterns during the parasite life cycle. Recombinant fragments corresponding to the middle and C-terminal regions of PyMSP1 and PyCSP, respectively, displayed strong reactivity against P. yoelii -infected mice sera. Specific native antigens invoking strong humoral immune response during the primary and secondary infections of P. yoelii were also abundantly detected in experimental ICR mice. The low or negligible parasitemia observed in the secondary infected mice was likely to result from the neutralizing action of the protective antibodies. Identification of these antigenic proteins might provide the necessary information and means to characterize additional vaccine candidate antigens, selected solely on their ability to produce the protective antibodies.

  8. Pseudodynamic Source Characterization for Strike-Slip Faulting Including Stress Heterogeneity and Super-Shear Ruptures

    KAUST Repository

    Mena, B.; Dalguer, L. A.; Mai, Paul Martin

    2012-01-01

    . (2004), we propose new relationships for PD models for moderate‐to‐large strike‐slip earthquakes that include local supershear rupture speed due to stress heterogeneities. We conduct dynamic rupture simulations using stochastic initial stress

  9. An epidemiological modelling study to estimate the composition of HIV-positive populations including migrants from endemic settings

    DEFF Research Database (Denmark)

    Nakagawa, F; Delpech, V; Albert, J

    2017-01-01

    were undiagnosed respectively. CONCLUSION: We have shown a working example to characterize the HIV population in a European context which incorporates migrants from countries with generalized epidemics. Despite all aspects of HIV care being free and widely available to anyone in need in the UK......OBJECTIVE: Migrants account for a significant number of people living with HIV in Europe, and it is important to fully consider this population in national estimates. Using a novel approach with the UK as an example, we present key public health measures of the HIV epidemic, taking into account...... of these people, 24 600 (15 000-36 200) were estimated to be undiagnosed; this number has remained stable over the last decade. An estimated 32% of the total undiagnosed population had CD4 cell count less than 350 cells/μl in 2013. Twenty-five and 23% of black African men and women heterosexuals living with HIV...

  10. Results of a Saxitoxin Proficiency Test Including Characterization of Reference Material and Stability Studies

    Directory of Open Access Journals (Sweden)

    Kirsi Harju

    2015-11-01

    Full Text Available A saxitoxin (STX proficiency test (PT was organized as part of the Establishment of Quality Assurance for the Detection of Biological Toxins of Potential Bioterrorism Risk (EQuATox project. The aim of this PT was to provide an evaluation of existing methods and the European laboratories’ capabilities for the analysis of STX and some of its analogues in real samples. Homogenized mussel material and algal cell materials containing paralytic shellfish poisoning (PSP toxins were produced as reference sample matrices. The reference material was characterized using various analytical methods. Acidified algal extract samples at two concentration levels were prepared from a bulk culture of PSP toxins producing dinoflagellate Alexandrium ostenfeldii. The homogeneity and stability of the prepared PT samples were studied and found to be fit-for-purpose. Thereafter, eight STX PT samples were sent to ten participating laboratories from eight countries. The PT offered the participating laboratories the possibility to assess their performance regarding the qualitative and quantitative detection of PSP toxins. Various techniques such as official Association of Official Analytical Chemists (AOAC methods, immunoassays, and liquid chromatography-mass spectrometry were used for sample analyses.

  11. The Solution Set Characterization and Error Bound for the Extended Mixed Linear Complementarity Problem

    Directory of Open Access Journals (Sweden)

    Hongchun Sun

    2012-01-01

    Full Text Available For the extended mixed linear complementarity problem (EML CP, we first present the characterization of the solution set for the EMLCP. Based on this, its global error bound is also established under milder conditions. The results obtained in this paper can be taken as an extension for the classical linear complementarity problems.

  12. Development of a core set of SSR markers for the characterization of Gossypium germplasm

    Science.gov (United States)

    Molecular markers such as simple sequence repeats (SSR) are a useful tool for characterizing genetic diversity of Gossypium germplasm collections. Genetic profiles by DNA fingerprinting of cotton accessions can only be compared among different collections if a common set of molecular markers are us...

  13. An epidemiological modelling study to estimate the composition of HIV-positive populations including migrants from endemic settings.

    Science.gov (United States)

    Nakagawa, Fumiyo

    2017-01-28

    Migrants account for a significant number of people living with HIV in Europe, and it is important to fully consider this population in national estimates. Using a novel approach with the UK as an example, we present key public health measures of the HIV epidemic, taking into account both in-country infections and infections likely to have been acquired abroad. Mathematical model calibrated to extensive data sources. An individual-based stochastic simulation model is used to calibrate to routinely collected surveillance data in the UK. Data on number of new HIV diagnoses, number of deaths, CD4 cell count at diagnosis, as well as time of arrival into the UK for migrants and the annual number of people receiving care were used. An estimated 106 400 (90% plausibility range: 88 700-124 600) people were living with HIV in the UK in 2013. Twenty-three percent of these people, 24 600 (15 000-36 200) were estimated to be undiagnosed; this number has remained stable over the last decade. An estimated 32% of the total undiagnosed population had CD4 cell count less than 350 cells/μl in 2013. Twenty-five and 23% of black African men and women heterosexuals living with HIV were undiagnosed respectively. We have shown a working example to characterize the HIV population in a European context which incorporates migrants from countries with generalized epidemics. Despite all aspects of HIV care being free and widely available to anyone in need in the UK, there is still a substantial number of people who are not yet diagnosed and thus not in care.

  14. Aero-structural optimization of wind turbine blades using a reduced set of design load cases including turbulence

    DEFF Research Database (Denmark)

    Sessarego, Matias; Shen, Wen Zhong

    2018-01-01

    Modern wind turbine aero-structural blade design codes generally use a smaller fraction of the full design load base (DLB) or neglect turbulent inflow as defined by the International Electrotechnical Commission standards. The current article describes an automated blade design optimization method...... based on surrogate modeling that includes a very large number of design load cases (DLCs) including turbulence. In the present work, 325 DLCs representative of the full DLB are selected based on the message-passing-interface (MPI) limitations in Matlab. Other methods are currently being investigated, e.......g. a Python MPI implementation, to overcome the limitations in Matlab MPI and ultimately achieve a full DLB optimization framework. The reduced DLB and the annual energy production are computed using the state-of-the-art aero-servo-elastic tool HAWC2. Furthermore, some of the interior dimensions of the blade...

  15. Methods to characterize environmental settings of stream and groundwater sampling sites for National Water-Quality Assessment

    Science.gov (United States)

    Nakagaki, Naomi; Hitt, Kerie J.; Price, Curtis V.; Falcone, James A.

    2012-01-01

    Characterization of natural and anthropogenic features that define the environmental settings of sampling sites for streams and groundwater, including drainage basins and groundwater study areas, is an essential component of water-quality and ecological investigations being conducted as part of the U.S. Geological Survey's National Water-Quality Assessment program. Quantitative characterization of environmental settings, combined with physical, chemical, and biological data collected at sampling sites, contributes to understanding the status of, and influences on, water-quality and ecological conditions. To support studies for the National Water-Quality Assessment program, a geographic information system (GIS) was used to develop a standard set of methods to consistently characterize the sites, drainage basins, and groundwater study areas across the nation. This report describes three methods used for characterization-simple overlay, area-weighted areal interpolation, and land-cover-weighted areal interpolation-and their appropriate applications to geographic analyses that have different objectives and data constraints. In addition, this document records the GIS thematic datasets that are used for the Program's national design and data analyses.

  16. Characterization of Joint Sets Through UAV Photogrammetry on Sedimentary Rock Sea Cliffs and Abrasion Platforms in Northern Taiwan

    Science.gov (United States)

    Hsieh, P. C.; LU, A.; Yeh, C. H.; Huang, W. K.; Lin, H. H.; Lin, M. L.

    2017-12-01

    Rockfall hazards are very common in obsequent slope and oblique slope. In the coastal area of northern Taiwan, many sea cliffs are formed by obsequent slope and oblique slope. A famous case of rockfall failure happened on Aug. 31, 2013, a 150-ton rock block fell on the highway in Badouzi, Keelung, during a high intensity rainfall event which was caused by Typhoon No.15 (Kong-rey). To reduce this kind of rockfall hazard, it is important to characterize discontinuous planes in the bedrock because rock blocks are mainly divided from bedrock by two or more sets of discontinuous planes including joint planes and the bedding plane. For doing characterization of those fracture patterns of joint sets, it is necessary to do detailed field investigations. However, the survey of discontinuous planes, especially joint sets, are usually difficult and cannot get enough characterization data about joint sets. The first reason is that doing field investigations on the surface of sea cliffs is very dangerous and difficult for engineers or geologists to approach the upper part of outcrop. The second reason is the complexity of joint sets. In Badouzi area, each cliff is constituted by many different layers such as sandstone, shale, or alternations of sandstone and shale, and each layer has different fracture pattern of joint sets. In this study, we use UAV photogrammetry as a solution of these difficulties. UAV photogrammetry can produce a high-resolution digital surface model (DSM), orthophoto, and anaglyph of sea cliffs and abrasion platforms. Than we use self-developed geoprocessing toolsets to auto-trace joint planes with DSM data and produce fracture pattern of joint sets semi-automatically and systematically. Our method can provide basic information for rock mass rating on rock slope stability and rockfall hazards evaluation.

  17. Surface wave site characterization at 27 locations near Boston, Massachusetts, including 2 strong-motion stations

    Science.gov (United States)

    Thompson, Eric M.; Carkin, Bradley A.; Baise, Laurie G.; Kayen, Robert E.

    2014-01-01

    The geotechnical properties of the soils in and around Boston, Massachusetts, have been extensively studied. This is partly due to the importance of the Boston Blue Clay and the extent of landfill in the Boston area. Although New England is not a region that is typically associated with seismic hazards, there have been several historical earthquakes that have caused significant ground shaking (for example, see Street and Lacroix, 1979; Ebel, 1996; Ebel, 2006). The possibility of strong ground shaking, along with heightened vulnerability from unreinforced masonry buildings, motivates further investigation of seismic hazards throughout New England. Important studies that are pertinent to seismic hazards in New England include source-parameter studies (Somerville and others, 1987; Boore and others, 2010), wave-propagation studies (Frankel, 1991; Viegas and others, 2010), empirical ground-motion prediction equations (GMPE) for computing ground-motion intensity (Tavakoli and Pezeshk, 2005; Atkinson and Boore, 2006), site-response studies (Hayles and others, 2001; Ebel and Kim, 2006), and liquefaction studies (Brankman and Baise, 2008). The shear-wave velocity (VS) profiles collected for this report are pertinent to the GMPE, site response, and liquefaction aspects of seismic hazards in the greater Boston area. Besides the application of these data for the Boston region, the data may be applicable throughout New England, through correlations with geologic units (similar to Ebel and Kim, 2006) or correlations with topographic slope (Wald and Allen, 2007), because few VS measurements are available in stable tectonic regions.Ebel and Hart (2001) used felt earthquake reports to infer amplification patterns throughout the greater Boston region and noted spatial correspondence with the dominant period and amplification factors obtained from ambient noise (horizontal-to-vertical ratios) by Kummer (1998). Britton (2003) compiled geotechnical borings in the area and produced a

  18. Risk Factors for Pressure Ulcers Including Suspected Deep Tissue Injury in Nursing Home Facility Residents: Analysis of National Minimum Data Set 3.0.

    Science.gov (United States)

    Ahn, Hyochol; Cowan, Linda; Garvan, Cynthia; Lyon, Debra; Stechmiller, Joyce

    2016-04-01

    To provide information on risk factors associated with pressure ulcers (PrUs), including suspected deep tissue injury (sDTI), in nursing home residents in the United States. This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. After participating in this educational activity, the participant should be better able to:1. Examine the literature related to risk factors for the development of PrUs.2. Compare risk factors associated with the prevalence of PrUs and sDTI from the revised Minimum Data Set 3.0 2012 using a modified Defloor's conceptual model of PrUs as a theoretical framework. This study aims to characterize and compare risk factors associated with pressure ulcers (PrUs), including suspected deep tissue injury (sDTI), in nursing home (NH) residents in the United States. Secondary analysis of the 2012 Minimum Data Set (MDS 3.0). Medicare- or Medicaid-certified NHs in the United States. Nursing home residents (n = 2,936,146) 18 years or older with complete PrU data, who received comprehensive assessments from January to December 2012. Pressure ulcer by stage was the outcome variable. Explanatory variables (age, gender, race and ethnicity, body mass index, skin integrity, system failure, disease, infection, mobility, and cognition) from the MDS 3.0 were aligned with the 4 elements of Defloor's conceptual model: compressive forces, shearing forces, tissue tolerance for pressure, and tissue tolerance for oxygen. Of 2,936,146 NH residents who had complete data for PrU, 89.9% had no PrU; 8.4% had a Stage 2, 3, or 4 or unstagable PrU; and 1.7% had an sDTI. The MDS variables corresponding to the 4 elements of Defloor's model were significantly predictive of both PrU and sDTI. Black residents had the highest risk of any-stage PrU, and Hispanic residents had the highest risk of sDTI. Skin integrity, system failure, infection, and disease risk factors had larger effect sizes for sDTI than for other PrU stages

  19. Systemic characterization and evaluation of particle packings as initial sets for discrete element simulations

    Science.gov (United States)

    Morfa, Carlos Recarey; Cortés, Lucía Argüelles; Farias, Márcio Muniz de; Morales, Irvin Pablo Pérez; Valera, Roberto Roselló; Oñate, Eugenio

    2018-07-01

    A methodology that comprises several characterization properties for particle packings is proposed in this paper. The methodology takes into account factors such as dimension and shape of particles, space occupation, homogeneity, connectivity and isotropy, among others. This classification and integration of several properties allows to carry out a characterization process to systemically evaluate the particle packings in order to guarantee the quality of the initial meshes in discrete element simulations, in both the micro- and the macroscales. Several new properties were created, and improvements in existing ones are presented. Properties from other disciplines were adapted to be used in the evaluation of particle systems. The methodology allows to easily characterize media at the level of the microscale (continuous geometries—steels, rocks microstructures, etc., and discrete geometries) and the macroscale. A global, systemic and integral system for characterizing and evaluating particle sets, based on fuzzy logic, is presented. Such system allows researchers to have a unique evaluation criterion based on the aim of their research. Examples of applications are shown.

  20. Systemic characterization and evaluation of particle packings as initial sets for discrete element simulations

    Science.gov (United States)

    Morfa, Carlos Recarey; Cortés, Lucía Argüelles; Farias, Márcio Muniz de; Morales, Irvin Pablo Pérez; Valera, Roberto Roselló; Oñate, Eugenio

    2017-10-01

    A methodology that comprises several characterization properties for particle packings is proposed in this paper. The methodology takes into account factors such as dimension and shape of particles, space occupation, homogeneity, connectivity and isotropy, among others. This classification and integration of several properties allows to carry out a characterization process to systemically evaluate the particle packings in order to guarantee the quality of the initial meshes in discrete element simulations, in both the micro- and the macroscales. Several new properties were created, and improvements in existing ones are presented. Properties from other disciplines were adapted to be used in the evaluation of particle systems. The methodology allows to easily characterize media at the level of the microscale (continuous geometries—steels, rocks microstructures, etc., and discrete geometries) and the macroscale. A global, systemic and integral system for characterizing and evaluating particle sets, based on fuzzy logic, is presented. Such system allows researchers to have a unique evaluation criterion based on the aim of their research. Examples of applications are shown.

  1. Production and characterization of setting hydraulic cements based on calcium phosphate

    International Nuclear Information System (INIS)

    Oliveira, Luci C. de; Rigo, Eliana C.S.; Santos, Luis A dos; Boschi, Anselmo Ortega; Carrodeguas, Raul G.

    1997-01-01

    Setting hydraulic cements based on calcium phosphate has risen great interest in scientific literature during recent years due to their total bio compatibility and to the fact that they harden 'in situ', providing easy handling and adaptation to the shape and dimensions of the defect which requires correction, differently from the predecessors, the calcium phosphate ceramics (Hydroxy apatite, β-tri calcium phosphate, biphasic, etc) in the shape of dense or porous blocks and grains. In the work, three calcium-phosphate cement compositions were studied. The resulting compositions were characterized according to the following aspects: setting times, pH, mechanical resistance, crystalline phases, microstructure and solubility in SBF (Simulated Body Fluid). The results show a potential use for the compositions. (author)

  2. Phenotypic plasticity, QTL mapping and genomic characterization of bud set in black poplar

    Directory of Open Access Journals (Sweden)

    Fabbrini Francesco

    2012-04-01

    Full Text Available Abstract Background The genetic control of important adaptive traits, such as bud set, is still poorly understood in most forest trees species. Poplar is an ideal model tree to study bud set because of its indeterminate shoot growth. Thus, a full-sib family derived from an intraspecific cross of P. nigra with 162 clonally replicated progeny was used to assess the phenotypic plasticity and genetic variation of bud set in two sites of contrasting environmental conditions. Results Six crucial phenological stages of bud set were scored. Night length appeared to be the most important signal triggering the onset of growth cessation. Nevertheless, the effect of other environmental factors, such as temperature, increased during the process. Moreover, a considerable role of genotype × environment (G × E interaction was found in all phenological stages with the lowest temperature appearing to influence the sensitivity of the most plastic genotypes. Descriptors of growth cessation and bud onset explained the largest part of phenotypic variation of the entire process. Quantitative trait loci (QTL for these traits were detected. For the four selected traits (the onset of growth cessation (date2.5, the transition from shoot to bud (date1.5, the duration of bud formation (subproc1 and bud maturation (subproc2 eight and sixteen QTL were mapped on the maternal and paternal map, respectively. The identified QTL, each one characterized by small or modest effect, highlighted the complex nature of traits involved in bud set process. Comparison between map location of QTL and P. trichocarpa genome sequence allowed the identification of 13 gene models, 67 bud set-related expressional and six functional candidate genes (CGs. These CGs are functionally related to relevant biological processes, environmental sensing, signaling, and cell growth and development. Some strong QTL had no obvious CGs, and hold great promise to identify unknown genes that affect bud set

  3. Exhaustively characterizing feasible logic models of a signaling network using Answer Set Programming.

    Science.gov (United States)

    Guziolowski, Carito; Videla, Santiago; Eduati, Federica; Thiele, Sven; Cokelaer, Thomas; Siegel, Anne; Saez-Rodriguez, Julio

    2013-09-15

    Logic modeling is a useful tool to study signal transduction across multiple pathways. Logic models can be generated by training a network containing the prior knowledge to phospho-proteomics data. The training can be performed using stochastic optimization procedures, but these are unable to guarantee a global optima or to report the complete family of feasible models. This, however, is essential to provide precise insight in the mechanisms underlaying signal transduction and generate reliable predictions. We propose the use of Answer Set Programming to explore exhaustively the space of feasible logic models. Toward this end, we have developed caspo, an open-source Python package that provides a powerful platform to learn and characterize logic models by leveraging the rich modeling language and solving technologies of Answer Set Programming. We illustrate the usefulness of caspo by revisiting a model of pro-growth and inflammatory pathways in liver cells. We show that, if experimental error is taken into account, there are thousands (11 700) of models compatible with the data. Despite the large number, we can extract structural features from the models, such as links that are always (or never) present or modules that appear in a mutual exclusive fashion. To further characterize this family of models, we investigate the input-output behavior of the models. We find 91 behaviors across the 11 700 models and we suggest new experiments to discriminate among them. Our results underscore the importance of characterizing in a global and exhaustive manner the family of feasible models, with important implications for experimental design. caspo is freely available for download (license GPLv3) and as a web service at http://caspo.genouest.org/. Supplementary materials are available at Bioinformatics online. santiago.videla@irisa.fr.

  4. Test set up description and performances for HAWAII-2RG detector characterization at ESTEC

    Science.gov (United States)

    Crouzet, P.-E.; ter Haar, J.; de Wit, F.; Beaufort, T.; Butler, B.; Smit, H.; van der Luijt, C.; Martin, D.

    2012-07-01

    In the frame work of the European Space Agency's Cosmic Vision program, the Euclid mission has the objective to map the geometry of the Dark Universe. Galaxies and clusters of galaxies will be observed in the visible and near-infrared wavelengths by an imaging and spectroscopic channel. For the Near Infrared Spectrometer instrument (NISP), the state-of-the-art HAWAII-2RG detectors will be used, associated with the SIDECAR ASIC readout electronic which will perform the image frame acquisitions. To characterize and validate the performance of these detectors, a test bench has been designed, tested and validated. This publication describes the pre-tests performed to build the set up dedicated to dark current measurements and tests requiring reasonably uniform light levels (such as for conversion gain measurements). Successful cryogenic and vacuum tests on commercial LEDs and photodiodes are shown. An optimized feed through in stainless steel with a V-groove to pot the flex cable connecting the SIDECAR ASIC to the room temperature board (JADE2) has been designed and tested. The test set up for quantum efficiency measurements consisting of a lamp, a monochromator, an integrating sphere and set of cold filters, and which is currently under construction will ensure a uniform illumination across the detector with variations lower than 2%. A dedicated spot projector for intra-pixel measurements has been designed and built to reach a spot diameter of 5 μm at 920nm with 2nm of bandwidth [1].

  5. Multisource data set integration and characterization of uranium mineralization for the Montrose Quadrangle, Colorado

    International Nuclear Information System (INIS)

    Bolivar, S.L.; Balog, S.H.; Campbell, K.; Fugelso, L.E.; Weaver, T.A.; Wecksung, G.W.

    1981-04-01

    Several data-classification schemes were developed by the Los Alamos National Laboratory to detect potential uranium mineralization in the Montrose 1 0 x 2 0 quadrangle, Colorado. A first step was to develop and refine the techniques necessary to digitize, integrate, and register various large geological, geochemical, and geophysical data sets, including Landsat 2 imagery, for the Montrose quadrangle, Colorado, using a grid resolution of 1 km. All data sets for the Montrose quadrangle were registered to the Universal Transverse Mercator projection. The data sets include hydrogeochemical and stream sediment analyses for 23 elements, uranium-to-thorium ratios, airborne geophysical survey data, the locations of 90 uranium occurrences, a geologic map and Landsat 2 (bands 4 through 7) imagery. Geochemical samples were collected from 3965 locations in the 19 200 km 2 quadrangle; aerial data were collected on flight lines flown with 3 to 5 km spacings. These data sets were smoothed by universal kriging and interpolated to a 179 x 119 rectangular grid. A mylar transparency of the geologic map was prepared and digitized. Locations for the known uranium occurrences were also digitized. The Landsat 2 imagery was digitally manipulated and rubber-sheet transformed to quadrangle boundaries and bands 4 through 7 were resampled to both a 1-km and 100-m resolution. All possible combinations of three, for all data sets, were examined for general geologic correlations by utilizing a color microfilm output. Subsets of data were further examined for selected test areas. Two classification schemes for uranium mineralization, based on selected test areas in both the Cochetopa and Marshall Pass uranium districts, are presented. Areas favorable for uranium mineralization, based on these schemes, were identified and are discussed

  6. Definitive Characterization of CA 19-9 in Resectable Pancreatic Cancer Using a Reference Set of Serum and Plasma Specimens.

    Science.gov (United States)

    Haab, Brian B; Huang, Ying; Balasenthil, Seetharaman; Partyka, Katie; Tang, Huiyuan; Anderson, Michelle; Allen, Peter; Sasson, Aaron; Zeh, Herbert; Kaul, Karen; Kletter, Doron; Ge, Shaokui; Bern, Marshall; Kwon, Richard; Blasutig, Ivan; Srivastava, Sudhir; Frazier, Marsha L; Sen, Subrata; Hollingsworth, Michael A; Rinaudo, Jo Ann; Killary, Ann M; Brand, Randall E

    2015-01-01

    The validation of candidate biomarkers often is hampered by the lack of a reliable means of assessing and comparing performance. We present here a reference set of serum and plasma samples to facilitate the validation of biomarkers for resectable pancreatic cancer. The reference set includes a large cohort of stage I-II pancreatic cancer patients, recruited from 5 different institutions, and relevant control groups. We characterized the performance of the current best serological biomarker for pancreatic cancer, CA 19-9, using plasma samples from the reference set to provide a benchmark for future biomarker studies and to further our knowledge of CA 19-9 in early-stage pancreatic cancer and the control groups. CA 19-9 distinguished pancreatic cancers from the healthy and chronic pancreatitis groups with an average sensitivity and specificity of 70-74%, similar to previous studies using all stages of pancreatic cancer. Chronic pancreatitis patients did not show CA 19-9 elevations, but patients with benign biliary obstruction had elevations nearly as high as the cancer patients. We gained additional information about the biomarker by comparing two distinct assays. The two CA 9-9 assays agreed well in overall performance but diverged in measurements of individual samples, potentially due to subtle differences in antibody specificity as revealed by glycan array analysis. Thus, the reference set promises be a valuable resource for biomarker validation and comparison, and the CA 19-9 data presented here will be useful for benchmarking and for exploring relationships to CA 19-9.

  7. Definitive Characterization of CA 19-9 in Resectable Pancreatic Cancer Using a Reference Set of Serum and Plasma Specimens.

    Directory of Open Access Journals (Sweden)

    Brian B Haab

    Full Text Available The validation of candidate biomarkers often is hampered by the lack of a reliable means of assessing and comparing performance. We present here a reference set of serum and plasma samples to facilitate the validation of biomarkers for resectable pancreatic cancer. The reference set includes a large cohort of stage I-II pancreatic cancer patients, recruited from 5 different institutions, and relevant control groups. We characterized the performance of the current best serological biomarker for pancreatic cancer, CA 19-9, using plasma samples from the reference set to provide a benchmark for future biomarker studies and to further our knowledge of CA 19-9 in early-stage pancreatic cancer and the control groups. CA 19-9 distinguished pancreatic cancers from the healthy and chronic pancreatitis groups with an average sensitivity and specificity of 70-74%, similar to previous studies using all stages of pancreatic cancer. Chronic pancreatitis patients did not show CA 19-9 elevations, but patients with benign biliary obstruction had elevations nearly as high as the cancer patients. We gained additional information about the biomarker by comparing two distinct assays. The two CA 9-9 assays agreed well in overall performance but diverged in measurements of individual samples, potentially due to subtle differences in antibody specificity as revealed by glycan array analysis. Thus, the reference set promises be a valuable resource for biomarker validation and comparison, and the CA 19-9 data presented here will be useful for benchmarking and for exploring relationships to CA 19-9.

  8. [Therapeutic effects of venlafaxine extended release for patients with depressive and anxiety disorders in the German outpatient setting - results of 2 observational studies including 8500 patients].

    Science.gov (United States)

    Anghelescu, I-G; Dierkes, W; Volz, H-P; Loeschmann, P-A; Schmitt, A B

    2009-11-01

    The therapeutic effects of venlafaxine extended release have been investigated by two prospective observational studies including 8506 patients in the outpatient setting of office based general practitioners and specialists. The efficacy has been documented by the Clinical Global Impression (CGI) scale and by the Hamilton depression (HAMD-21) scale. The tolerability has been assessed by the documentation of adverse events. About (2/3) of the patients were treated because of depression and about (1/3) mainly because of anxiety disorder. The patients of specialists did receive higher dosages and were more severely affected. The response rate on the CGI scale was 87.4 for the patients of general practitioners and 74.2 % for the patients of specialists. The results of the HAMD-21 scale, which has been used by specialists, showed a response rate of 71.8 and a remission rate of 56.3 %. These positive effects could be demonstrated even for the more severely and chronically affected patients. The incidence of adverse events was low in both studies and comparable to the tolerability profile of randomized studies. Importantly, the good tolerability profile was similar even for patients with concomitant cardiovascular disease. In conclusion, these results confirm the efficacy and good tolerability of venlafaxine extended release in the outpatient setting in Germany. Georg Thieme Verlag KG Stuttgart, New York.

  9. Development of a comprehensive survey of sexuality issues including a self-report version of the International Spinal Cord Injury sexual function basic data sets.

    Science.gov (United States)

    New, P W; Currie, K E

    2016-08-01

    Questionnaire development, validation and completion. Develop comprehensive survey of sexuality issues including validated self-report versions of the International Spinal Cord Injury male sexual function and female sexual and reproductive function basic data sets (SR-iSCI-sexual function). People with spinal cord damage (SCD) living in the community, Australia from August 2013 to June 2014. An iterative process involving rehabilitation medicine clinicians, a nurse specialising in sexuality issues in SCD and people with SCD who developed a comprehensive survey that included the SR-iSCI-sexual function. Participants recruitment through spinal rehabilitation review clinic and community organisations that support people with SCD. Surveys completed by 154 people. Most were male (n=101, 65.6%). Respondents' median age was 50 years (interquartile range (IQR) 38-58), and they were a median of 10 years (IQR 4-20) after the onset of SCD. Sexual problems unrelated to SCD were reported by 12 (8%) respondents, and 114 (n=75.5%) reported sexual problems because of SCD. Orgasms were much less likely (χ(2)=13.1, P=0.006) to be normal in males (n=5, 5%) compared with females (n=11, 22%). Males had significantly worse (χ(2)=26.0, P=0.001) psychogenic genital functioning (normal n=9, 9%) than females (normal n=13, 26%) and worse (χ(2)=10.8, P=0.013) reflex genital functioning. Normal ejaculation was reported in only three (3%) men. Most (n=26, 52%) women reported reduced or absent menstruation pattern since SCD. The SR-iSCI-sexual function provides a useful tool for researchers and clinicians to collect information regarding patient-reported sexual functioning after SCD and to facilitate comparative studies.

  10. Effectiveness of a structured motivational intervention including smoking cessation advice and spirometry information in the primary care setting: the ESPITAP study

    Directory of Open Access Journals (Sweden)

    Martin-Lujan Francisco

    2011-11-01

    Full Text Available Abstract Background There is current controversy about the efficacy of smoking cessation interventions that are based on information obtained by spirometry. The objective of this study is to evaluate the effectiveness in the primary care setting of structured motivational intervention to achieve smoking cessation, compared with usual clinical practice. Methods Design Multicentre randomized clinical trial with an intervention and a control group. Setting 12 primary care centres in the province of Tarragona (Spain. Subjects of study 600 current smokers aged between 35 and 70 years with a cumulative habit of more than 10 packs of cigarettes per year, attended in primary care for any reason and who did not meet any of the exclusion criteria for the study, randomly assigned to structured intervention or standard clinical attention. Intervention Usual advice to quit smoking by a general practitioner as well as a 20-minute personalized visit to provide detailed information about spirometry results, during which FEV1, FVC, FEF 25-75% and PEF measurements were discussed and interpreted in terms of theoretical values. Additional information included the lung age index (defined as the average age of a non-smoker with the same FEV1 as the study participant, comparing this with the chronological age to illustrate the pulmonary deterioration that results from smoking. Measurements Spirometry during the initial visit. Structured interview questionnaire administered at the primary care centre at the initial visit and at 12-month follow-up. Telephone follow-up interview at 6 months. At 12-month follow-up, expired CO was measured in patients who claimed to have quit smoking. Main variables Smoking cessation at 12 months. Analysis Data will be analyzed on the basis of "intention to treat" and the unit of analysis will be the individual smoker. Expected results Among active smokers treated in primary care we anticipate significantly higher smoking cessation in the

  11. Characterizing the geomorphic setting of precariously balanced rocks using terrestrial laser scanning technology

    Science.gov (United States)

    Haddad, D. E.; Arrowsmith, R.

    2009-12-01

    Terrestrial laser scanning (TLS) technology is rapidly becoming an effective three-dimensional imaging tool. Precariously balanced rocks are a subset of spheroidally weathered boulders. They are balanced on bedrock pedestals and are formed in upland drainage basins and pediments of exhumed plutons. Precarious rocks are used as negative evidence of earthquake-driven extreme ground motions. Field surveys of PBRs are coupled with cosmogenic radionuclide (CRN) surface exposure dating techniques to determine their exhumation rates. These rates are used in statistical simulations to estimate the magnitudes and recurrences of earthquake-generated extreme ground shaking as a means to physically validate seismic hazard analyses. However, the geomorphic setting of PBRs in the landscape is poorly constrained when interpreting their exhumation rates from CRN surface exposure dates. Are PBRs located on steep or gentle hillslopes? Are they located near drainages or hillslope crests? What geomorphic processes control the spatial distribution of PBRs in a landscape, and where do these processes dominate? Because the fundamental hillslope transport laws are largely controlled by local hillslope gradient and contributing area, the location of a PBR is controlled by the geomorphic agents and their rates acting on it. Our latest efforts involve using a combination of TLS and airborne laser swath mapping (ALSM) to characterize the geomorphic situation of PBRs. We used a Riegl LPM 800i (LPM 321) terrestrial laser scanner to scan a ~1.5 m tall by ~1 m wide precariously balanced rock in the Granite Dells, central Arizona. The PBR was scanned from six positions, and the scans were aligned to a point cloud totaling 3.4M points. We also scanned a ~50 m by ~150 m area covering PBR hillslopes from five scan positions. The resulting 5.5M points were used to create a digital terrain model of precarious rocks and their hillslopes. Our TLS- and ALSM-generated surface models and DEMs provide a

  12. Characterization of the order relation on the set of completely n-positive linear maps between C*-algebras

    Directory of Open Access Journals (Sweden)

    Maria Joita

    2007-12-01

    Full Text Available In this paper we characterize the order relation on the set of all nondegenerate completely n-positive linear maps between C*-algebras in terms of a self-dual Hilbert module induced by each completely n-positive linear map.

  13. Characterization of Groundwater Quality Based on Regional Geologic Setting in the Piedmont and Blue Ridge Physiographic Provinces, North Carolina

    Science.gov (United States)

    Harden, Stephen L.; Chapman, Melinda J.; Harned, Douglas A.

    2009-01-01

    A compilation of groundwater-quality data collected as part of two U.S. Geological Survey studies provides a basis for understanding the ambient geochemistry related to geologic setting in the Piedmont and Blue Ridge Physiographic Provinces (hereafter referred to as Piedmont and Mountains Provinces) of North Carolina. Although the geology is complex, a grouping of the sampled wells into assemblages of geologic units described as 'geozones' provides a basis for comparison across the region. Analyses of these two data sets provide a description of water-quality conditions in bedrock aquifers of the Piedmont and Mountains Provinces of North Carolina. Analyzed data were collected between 1997 and 2008 from a network of 79 wells representing 8 regional geozones distributed throughout the Piedmont and Mountains Provinces. This area has experienced high rates of population growth and an increased demand for water resources. Groundwater was used by about 34 percent of the population in the 65 counties of this region in 2005. An improved understanding of the quality and quantity of available groundwater resources is needed to plan effectively for future growth and development. The use of regional geologic setting to characterize groundwater-quality conditions in the Piedmont and Mountains Provinces is the focus of this investigation. Data evaluation included an examination of selected properties and the ionic composition of groundwater in the geozones. No major differences in overall ionic chemistry of groundwater among the geozones were evident with the data examined. Variability in the cationic and anionic composition of groundwater within a particular geozone appeared to reflect local differences in lithologic setting, hydrologic and geochemical conditions, and(or) land-use effects. The most common exceedances of the drinking-water criteria (in accordance with Federal and State water-quality standards) occurred for radon, pH, manganese, iron, and zinc. Radon had the most

  14. Using Vertical Electrical Soundings for Characterizing Hydrogeological and Tectonic Settings in Deir El-Adas Area, Yarmouk Basin, Syria

    Science.gov (United States)

    Al-Fares, Walid

    2016-06-01

    The present study is aimed at characterizing the subsurface geological and tectonic structure in Deir El-Adas area, by using Vertical Electrical Sounding survey (VES) and hydrogeological investigations, in order to determine the causes of the failure for the majority of the wells drilled in the area. The survey data was treated in three different approaches including direct VES inversion, pseudo-2D method and horizontal profiling, in order to maximize the reliability of the data interpretation. The results revealed the presence of a local faulted anticline structure at the top of the Paleogene formation, underneath the basaltic outcrops where Deir El-Adas village is situated. The appearance of this subsurface anticline structure has complicated the local hydro-geological situation, and most likely led to limitation of the groundwater recharge in the area. Moreover, the performed piezometric and discharge maps indicated the presence of a notable groundwater watershed, in addition to feeble water productivity of the wells drilled adjacent to Deir El-Adas, mostly related to the subsurface geological and tectonic settings in the area.

  15. Figures of merit and constraints from testing general relativity using the latest cosmological data sets including refined COSMOS 3D weak lensing

    International Nuclear Information System (INIS)

    Dossett, Jason N.; Moldenhauer, Jacob; Ishak, Mustapha

    2011-01-01

    We use cosmological constraints from current data sets and a figure of merit approach in order to probe any deviations from general relativity at cosmological scales. The figure of merit approach is used to study and compare the constraining power of various combinations of data sets on the modified gravity (MG) parameters. We use the recently refined HST-COSMOS weak-lensing tomography data, the ISW-galaxy cross correlations from 2MASS and SDSS luminous red galaxy surveys, the matter power spectrum from SDSS-DR7 (MPK), the WMAP7 temperature and polarization spectra, the baryon acoustic oscillations from Two-Degree Field and SDSS-DR7, and the Union2 compilation of type Ia supernovae, in addition to other bounds from Hubble parameter measurements and big bang nucleosynthesis. We use three parametrizations of MG parameters that enter the perturbed field equations. In order to allow for variations of the parameters with the redshift and scale, the first two parametrizations use recently suggested functional forms while the third is based on binning methods. Using the first parametrization, we find that the CMB+ISW+WL combination provides the strongest constraints on the MG parameters followed by CMB+WL or CMB+MPK+ISW. Using the second parametrization or the binning methods, we find that the combination CMB+MPK+ISW consistently provides some of the strongest constraints. This shows that the constraints are parametrization dependent. We find that adding up current data sets does not improve consistently the uncertainties on MG parameters due to tensions between the best-fit MG parameters preferred by different data sets. Furthermore, some functional forms imposed by the parametrizations can lead to an exacerbation of these tensions. Next, unlike some studies that used the CFHTLS lensing data, we do not find any deviation from general relativity using the refined HST-COSMOS data, confirming previous claims in those studies that their result may have been due to some

  16. Automatic ice-cream characterization by impedance measurements for optimal machine setting

    OpenAIRE

    Grossi , Marco; Lanzoni , Massimo; Lazzarini , Roberto; Riccò , Bruno

    2012-01-01

    International audience; Electrical characterization of products is gaining increasing interest in the food industry for quality monitoring and control. In particular, this is the case in the ice-cream industry, where machines dedicated to store ice-cream mixes are programmed ''ad hoc'' for different groups of products. To this purpose, the present work shows that essential product classification (discrimination between milk based and fruit based ice-cream mixes) can be done by means of a tech...

  17. Data linkage of inpatient hospitalization and workers' claims data sets to characterize occupational falls.

    Science.gov (United States)

    Bunn, Terry L; Slavova, Svetla; Bathke, Arne

    2007-07-01

    The identification of industry, occupation, and associated injury costs for worker falls in Kentucky have not been fully examined. The purpose of this study was to determine the associations between industry and occupation and 1) hospitalization length of stay; 2) hospitalization charges; and 3) workers' claims costs in workers suffering falls, using linked inpatient hospitalization discharge and workers' claims data sets. Hospitalization cases were selected with ICD-9-CM external cause of injury codes for falls and payer code of workers' claims for years 2000-2004. Selection criteria for workers'claims cases were International Association of Industrial Accident Boards and Commissions Electronic Data Interchange Nature (IAIABCEDIN) injuries coded as falls and/or slips. Common data variables between the two data sets such as date of birth, gender, date of injury, and hospital admission date were used to perform probabilistic data linkage using LinkSolv software. Statistical analysis was performed with non-parametric tests. Construction falls were the most prevalent for male workers and incurred the highest hospitalization and workers' compensation costs, whereas most female worker falls occurred in the services industry. The largest percentage of male worker falls was from one level to another, while the largest percentage of females experienced a fall, slip, or trip (not otherwise classified). When male construction worker falls were further analyzed, laborers and helpers had longer hospital stays as well as higher total charges when the worker fell from one level to another. Data linkage of hospitalization and workers' claims falls data provides additional information on industry, occupation, and costs that are not available when examining either data set alone.

  18. Chromatographic, Spectrometric and NMR Characterization of a New Set of Glucuronic Acid Esters Synthesized by Lipase

    Directory of Open Access Journals (Sweden)

    Michel Marlier

    2007-01-01

    Full Text Available An enzymatic synthesis was developed on a new set of D-glucuronic acid esters and particularly the tetradecyl-D-glucopyranosiduronate also named tetradecyl D-glucuronate. Chromatographic analyses revealed the presence of the ester as a mixture of anomeric forms for carbon chain lengths superior to 12. TOF/MS and MS/MS studies confirmed the synthesis of glucuronic acid ester. The NMR study also confirmed the structure of glucuronic acid esters and clearly revealed an anomeric (α/β ratio equivalent to 3/2

  19. Data Set for Characterization of nanoparticles in wood based consumer products

    Data.gov (United States)

    U.S. Environmental Protection Agency — The data include is for all of the tables and figures associated with the published journal article. This dataset is associated with the following publication:...

  20. Systematic review including re-analyses of 1148 individual data sets of central venous pressure as a predictor of fluid responsiveness

    DEFF Research Database (Denmark)

    Eskesen, T G; Wetterslev, M; Perner, A

    2016-01-01

    PURPOSE: Central venous pressure (CVP) has been shown to have poor predictive value for fluid responsiveness in critically ill patients. We aimed to re-evaluate this in a larger sample subgrouped by baseline CVP values. METHODS: In April 2015, we systematically searched and included all clinical...

  1. Assessment of wind speed and wind power through three stations in Egypt, including air density variation and analysis results with rough set theory

    International Nuclear Information System (INIS)

    Essa, K.S.M.; Embaby, M.; Marrouf, A.A.; Koza, A.M.; Abd El-Monsef, M.E.

    2007-01-01

    It is well known that the wind energy potential is proportional to both air density and the third power of the wind speed average over a suitable time period. The wind speed and air density have random variables depending on both time and location. The main objective of this work is to derive the most general wind energy potential of the wind formulation putting into consideration the time variable in both wind speed and air density. The correction factor is derived explicitly in terms of the cross-correlation and the coefficients of variation.The application is performed for environmental and wind speed measurements at the Cairo Airport, Kosseir and Hurguada, Egypt. Comparisons are made between Weibull, Rayleigh, and actual data distributions of wind speed and wind power of one year 2005. A Weibull distribution is the best match to the actual probability distribution of wind speed data for most stations. The maximum wind energy potential was 373 W/m 2 in June at Hurguada (Red Sea coast) where the annual mean value was 207 W/m 2 . By Using Rough Set Theory, We Find That the Wind Power Depends on the Wind Speed with greater than air density

  2. Application of Karasek's demand/control model a Canadian occupational setting including shift workers during a period of reorganization and downsizing.

    Science.gov (United States)

    Schechter, J; Green, L W; Olsen, L; Kruse, K; Cargo, M

    1997-01-01

    To apply Karasek's Job Content Model to an analysis of the relationships between job type and perceived stress and stress behaviors in a large company during a period of reorganization and downsizing. Cross-sectional mail-out, mail-back survey. A large Canadian telephone/telecommunications company. Stratified random sample (stratified by job category) of 2200 out of 13,000 employees with a response rate of 48.8%. Responses to 25 of Karasek's core questions were utilized to define four job types: low-demand and high control = "relaxed"; high demand and high control = "active"; low demand and low control = "passive", and high demand and low control = "high strain." These job types were compared against self-reported stress levels, perceived general level of health, absenteeism, alcohol use, exercise level, and use of medications and drugs. Similar analyses were performed to assess the influence of shift work. Employees with "passive" or "high strain" job types reported higher levels of stress (trend test p Karasek and Theorell was validated in this setting with respect to stress and some stress-associated attitudes and behaviors.

  3. Fractional ablative erbium YAG laser: histological characterization of relationships between laser settings and micropore dimensions.

    Science.gov (United States)

    Taudorf, Elisabeth H; Haak, Christina S; Erlendsson, Andrés M; Philipsen, Peter A; Anderson, R Rox; Paasch, Uwe; Haedersdal, Merete

    2014-04-01

    Treatment of a variety of skin disorders with ablative fractional lasers (AFXL) is driving the development of portable AFXLs. This study measures micropore dimensions produced by a small 2,940 nm AFXL using a variety of stacked pulses, and determines a model correlating laser parameters with tissue effects. Ex vivo pig skin was exposed to a miniaturized 2,940 nm AFXL, spot size 225 µm, density 5%, power levels 1.15-2.22 W, pulse durations 50-225 microseconds, pulse repetition rates 100-500 Hz, and 2, 20, or 50 stacked pulses, resulting in pulse energies of 2.3-12.8 mJ/microbeam and total energy levels of 4.6-640 mJ/microchannel. Histological endpoints were ablation depth (AD), coagulation zone (CZ) and ablation width (AW). Data were logarithmically transformed if required prior to linear regression analyses. Results for histological endpoints were combined in a mathematical model. In 138 sections from 91 biopsies, AD ranged from 16 to a maximum of 1,348 µm and increased linearly with the logarithm of total energy delivered by stacked pulses, but also depended on variations in power, pulse duration, pulse repetition rate, and pulse energy (r(2)  = 0.54-0.85, P micropores of specific ADs with an associated range of CZs and AWs, for example, 300 µm ADs were associated with CZs from 27 to 73 µm and AWs from 190 to 347 µm. Pulse stacking with a small, low power 2,940 nm AFXL created reproducible shallow to deep micropores, and influenced micropore configuration. Mathematical modeling established relations between laser settings and micropore dimensions, which assists in choosing laser settings for desired tissue effects. © 2014 Wiley Periodicals, Inc.

  4. Combining in situ characterization methods in one set-up: looking with more eyes into the intricate chemistry of the synthesis and working of heterogeneous catalysts.

    Science.gov (United States)

    Bentrup, Ursula

    2010-12-01

    Several in situ techniques are known which allow investigations of catalysts and catalytic reactions under real reaction conditions using different spectroscopic and X-ray methods. In recent years, specific set-ups have been established which combine two or more in situ methods in order to get a more detailed understanding of catalytic systems. This tutorial review will give a summary of currently available set-ups equipped with multiple techniques for in situ catalyst characterization, catalyst preparation, and reaction monitoring. Besides experimental and technical aspects of method coupling including X-ray techniques, spectroscopic methods (Raman, UV-vis, FTIR), and magnetic resonance spectroscopies (NMR, EPR), essential results will be presented to demonstrate the added value of multitechnique in situ approaches. A special section is focussed on selected examples of use which show new developments and application fields.

  5. Characterization of emissions from a desktop 3D printer and indoor air measurements in office settings.

    Science.gov (United States)

    Steinle, Patrick

    2016-01-01

    Emissions from a desktop 3D printer based on fused deposition modeling (FDM) technology were measured in a test chamber and indoor air was monitored in office settings. Ultrafine aerosol (UFA) emissions were higher while printing a standard object with polylactic acid (PLA) than with acrylonitrile butadiene styrene (ABS) polymer (2.1 × 10(9) vs. 2.4 × 10(8) particles/min). Prolonged use of the printer led to higher emission rates (factor 2 with PLA and 4 with ABS, measured after seven months of occasional use). UFA consisted mainly of volatile droplets, and some small (100-300 nm diameter) iron containing and soot-like particles were found. Emissions of inhalable and respirable dust were below the limit of detection (LOD) when measured gravimetrically, and only slightly higher than background when measured with an aerosol spectrometer. Emissions of volatile organic compounds (VOC) were in the range of 10 µg/min. Styrene accounted for more than 50% of total VOC emitted when printing with ABS; for PLA, methyl methacrylate (MMA, 37% of TVOC) was detected as the predominant compound. Two polycyclic aromatic hydrocarbons (PAH), fluoranthene and pyrene, were observed in very low amounts. All other analyzed PAH, as well as inorganic gases and metal emissions except iron (Fe) and zinc (Zn), were below the LOD or did not differ from background without printing. A single 3D print (165 min) in a large, well-ventilated office did not significantly increase the UFA and VOC concentrations, whereas these were readily detectable in a small, unventilated room, with UFA concentrations increasing by 2,000 particles/cm(3) and MMA reaching a peak of 21 µg/m(3) and still being detectable in the room even 20 hr after printing.

  6. A set of triple-resonance nuclear magnetic resonance experiments for structural characterization of organophosphorus compounds in mixture samples

    Energy Technology Data Exchange (ETDEWEB)

    Koskela, Harri, E-mail: Harri.T.Koskela@helsinki.fi [VERIFIN, University of Helsinki, P.O. Box 55, FIN-00014 Helsinki (Finland)

    2012-11-02

    Highlights: Black-Right-Pointing-Pointer New {sup 1}H, {sup 13}C, {sup 31}P triple-resonance NMR pulse experiments. Black-Right-Pointing-Pointer Analysis of organophosphorus (OP) compounds in complex matrix. Black-Right-Pointing-Pointer Selective extraction of {sup 1}H, {sup 31}P, and {sup 13}C chemical shifts and connectivities. Black-Right-Pointing-Pointer More precise NMR identification of OP nerve agents and their degradation products. - Abstract: The {sup 1}H, {sup 13}C correlation NMR spectroscopy utilizes J{sub CH} couplings in molecules, and provides important structural information from small organic molecules in the form of carbon chemical shifts and carbon-proton connectivities. The full potential of the {sup 1}H, {sup 13}C correlation NMR spectroscopy has not been realized in the Chemical Weapons Convention (CWC) related verification analyses due to the sample matrix, which usually contains a high amount of non-related compounds obscuring the correlations of the relevant compounds. Here, the results of the application of {sup 1}H, {sup 13}C, {sup 31}P triple-resonance NMR spectroscopy in characterization of OP compounds related to the CWC are presented. With a set of two-dimensional triple-resonance experiments the J{sub HP}, J{sub CH} and J{sub PC} couplings are utilized to map the connectivities of the atoms in OP compounds and to extract the carbon chemical shift information. With the use of the proposed pulse sequences the correlations from the OP compounds can be recorded without significant artifacts from the non-OP compound impurities in the sample. Further selectivity of the observed correlations is achieved with the application of phosphorus band-selective pulse in the pulse sequences to assist the analysis of multiple OP compounds in mixture samples. The use of the triple-resonance experiments in the analysis of a complex sample is shown with a test mixture containing typical scheduled OP compounds, including the characteristic degradation

  7. Development of new auxiliary basis functions of the Karlsruhe segmented contracted basis sets including diffuse basis functions (def2-SVPD, def2-TZVPPD, and def2-QVPPD) for RI-MP2 and RI-CC calculations.

    Science.gov (United States)

    Hellweg, Arnim; Rappoport, Dmitrij

    2015-01-14

    We report optimized auxiliary basis sets for use with the Karlsruhe segmented contracted basis sets including moderately diffuse basis functions (Rappoport and Furche, J. Chem. Phys., 2010, 133, 134105) in resolution-of-the-identity (RI) post-self-consistent field (post-SCF) computations for the elements H-Rn (except lanthanides). The errors of the RI approximation using optimized auxiliary basis sets are analyzed on a comprehensive test set of molecules containing the most common oxidation states of each element and do not exceed those of the corresponding unaugmented basis sets. During these studies an unsatisfying performance of the def2-SVP and def2-QZVPP auxiliary basis sets for Barium was found and improved sets are provided. We establish the versatility of the def2-SVPD, def2-TZVPPD, and def2-QZVPPD basis sets for RI-MP2 and RI-CC (coupled-cluster) energy and property calculations. The influence of diffuse basis functions on correlation energy, basis set superposition error, atomic electron affinity, dipole moments, and computational timings is evaluated at different levels of theory using benchmark sets and showcase examples.

  8. Characterization and modeling of SET/RESET cycling induced read-disturb failure time degradation in a resistive switching memory

    Science.gov (United States)

    Su, Po-Cheng; Hsu, Chun-Chi; Du, Sin-I.; Wang, Tahui

    2017-12-01

    Read operation induced disturbance in SET-state in a tungsten oxide resistive switching memory is investigated. We observe that the reduction of oxygen vacancy density during read-disturb follows power-law dependence on cumulative read-disturb time. Our study shows that the SET-state read-disturb immunity progressively degrades by orders of magnitude as SET/RESET cycle number increases. To explore the cause of the read-disturb degradation, we perform a constant voltage stress to emulate high-field stress effects in SET/RESET cycling. We find that the read-disturb failure time degradation is attributed to high-field stress-generated oxide traps. Since the stress-generated traps may substitute for some of oxygen vacancies in forming conductive percolation paths in a switching dielectric, a stressed cell has a reduced oxygen vacancy density in SET-state, which in turn results in a shorter read-disturb failure time. We develop an analytical read-disturb degradation model including both cycling induced oxide trap creation and read-disturb induced oxygen vacancy reduction. Our model can well reproduce the measured read-disturb failure time degradation in a cycled cell without using fitting parameters.

  9. Production and characterization of protonated molecular clusters containing a given number of water molecules with the DIAM set-up

    International Nuclear Information System (INIS)

    Bruny, G.

    2010-01-01

    nano-scale characterization of irradiation in bio-molecular systems requires observation of novel features which are now achievable with the recent technical progress. This work is a central part in the development of DIAM which is a new experimental set-up devoted to irradiation of bio-molecular clusters at the Institut de Physique Nucleaire de Lyon. The development of the cluster source and of a double focusing mass spectrometer leads to the production of intense beams of mass selected protonated molecular clusters. Combined with this mass selected cluster beams an innovative detection technique is demonstrated in collision induced dissociation experiments. The results contribute to the knowledge of the stability and the structure of the small protonated water clusters and mixed clusters of water and pyridine. (author)

  10. Integration of NURE and other data sets, southwest Montana and northeast Idaho: an orientation study to characterize mineralized environments. National Uranium Resource Evaluation

    International Nuclear Information System (INIS)

    Madson, M.E.; Karp, K.E.; D'Andrea, R.F. Jr.; Morrison, B.C.

    1983-04-01

    Mineralized environments in the Dillon, Butte, Hamilton, and Elk City 1 0 x 2 0 NTMS Quadrangles were identified and characterized from the National Uranium Resource Evaluation (NURE) Hydrogeochemical and Stream Sediment Reconnaissance and Aerial Radiometric and Magnetic Survey data, folio data, and other data sets used in this study. Methods applied to reconnaissance for uranium during the NURE program were used successfully in this project to recognize and delineate locales that have mineral-resource potential. These methods included preparation and interpretation of maps of geochemical, aerial radiometric, and aeromagentic data, as well as interpretation of univariate and multivariate statistical analyses of NURE data sets. Data interpretations were conducted by a contingency approach that puts a variety of statistical and cartographic tools at the disposal of the geologist. These tools were applied selectively to the data until the geochemical and geophysical signature of an anomalous locale was described and characterized to the geologist's satisfaction. Ten areas known to be mineralized were described as type localities and used to calibrate the geochemical and geophysical models employed in the study. Other areas exhibiting anomalous geochemical and (or) geophysical characteristics were analogized to the type localities. Thirty anomalous areas were delineated during this study; 17 of the 30 are believed to warrant further investigation. Three locales contain Tertiary intrusive bodies that were delineated on the basis of their characteristic signatures and trace-element contents. 5 figures, 10 tables

  11. Characterization of Genotoxic Response to 15 Multiwalled Carbon Nanotubes with Variable Physicochemical Properties Including Surface Functionalizations in the FE1-Muta(TM) Mouse Lung Epithelial Cell Line

    DEFF Research Database (Denmark)

    Jackson, Petra; Kling, Kirsten; Jensen, Keld Alstrup

    2015-01-01

    Carbon nanotubes vary greatly in physicochemical properties. We compared cytotoxic and genotoxic response to 15 multiwalled carbon nanotubes (MWCNT) with varying physicochemical properties to identify drivers of toxic responses. The studied MWCNT included OECD Working Party on Manufactured...... Nanomaterials (WPMN) (NM-401, NM-402, and NM-403), materials (NRCWE-026 and MWCNT-XNRI-7), and three sets of surface-modified MWCNT grouped by physical characteristics (thin, thick, and short I-III, respectively). Each Groups I-III included pristine, hydroxylated and carboxylated MWCNT. Group III also included...... an amino-functionalized MWCNT. The level of surface functionalization of the MWCNT was low. The level and type of elemental impurities of the MWCNT varied by...

  12. Effects of manual threshold setting on image analysis results of a sandstone sample structural characterization by X-ray microtomography

    International Nuclear Information System (INIS)

    Moreira, Anderson C.; Fernandes, Celso P.; Fernandes, Jaquiel S.; Marques, Leonardo C.; Appoloni, Carlos R.; Nagata, Rodrigo

    2009-01-01

    X-ray microtomography is a nondestructive nuclear technique widely applied for samples structural characterization. This methodology permits the investigation of materials porous phase, without special sample preparation, generating bidimensional images of the irradiated sample. The images are generated by the linear attenuation coefficient mapping of the sample. In order to do a quantitative characterization, the images have to be binarized, separating porous phase from the material matrix. The choice of the correct threshold in the grey level histogram is an important and discerning procedure for the binary images creation. Slight variations of the threshold level led to substantial variations in physical parameters determination, like porosity and pore size distribution values. The aim of this work is to evaluate these variations based on some manual threshold setting. Employing Imago image analysis software, four operators determined the porosity and pore size distribution of a sandstone sample by image analysis. The microtomography measurements were accomplished with the following scan conditions: 60 kV, 165 μA, 1 mm Al filter, 0.45 deg step size and 180.0 deg total rotation angle with and 3.8 μm and 11 μm spatial resolution. The global average porosity values, determined by the operators, range from 27.8 to 32.4 % for 3.8 μm spatial resolution and 12.3 to 28.3 % for 11 μm spatial resolution. Percentage differences among the pore size distributions were also found. For the same pore size range, 5.5 % and 17.1 %, for 3.8 μm and 11 μm spatial resolutions respectively, were noted. (author)

  13. Characterization of Vibrio cholerae O1 El Tor Biotype Variant Clinical Isolates from Bangladesh and Haiti, Including a Molecular Genetic Analysis of Virulence Genes ▿

    Science.gov (United States)

    Son, Mike S.; Megli, Christina J.; Kovacikova, Gabriela; Qadri, Firdausi; Taylor, Ronald K.

    2011-01-01

    Vibrio cholerae serogroup O1, the causative agent of the diarrheal disease cholera, is divided into two biotypes: classical and El Tor. Both biotypes produce the major virulence factors toxin-coregulated pilus (TCP) and cholera toxin (CT). Although possessing genotypic and phenotypic differences, El Tor biotype strains displaying classical biotype traits have been reported and subsequently were dubbed El Tor variants. Of particular interest are reports of El Tor variants that produce various levels of CT, including levels typical of classical biotype strains. Here, we report the characterization of 10 clinical isolates from the International Centre for Diarrhoeal Disease Research, Bangladesh, and a representative strain from the 2010 Haiti cholera outbreak. We observed that all 11 strains produced increased CT (2- to 10-fold) compared to that of wild-type El Tor strains under in vitro inducing conditions, but they possessed various TcpA and ToxT expression profiles. Particularly, El Tor variant MQ1795, which produced the highest level of CT and very high levels of TcpA and ToxT, demonstrated hypervirulence compared to the virulence of El Tor wild-type strains in the infant mouse cholera model. Additional genotypic and phenotypic tests were conducted to characterize the variants, including an assessment of biotype-distinguishing characteristics. Notably, the sequencing of ctxB in some El Tor variants revealed two copies of classical ctxB, one per chromosome, contrary to previous reports that located ctxAB only on the large chromosome of El Tor biotype strains. PMID:21880975

  14. Comprehensive cytological characterization of the Gossypium hirsutum genome based on the development of a set of chromosome cytological markers

    Directory of Open Access Journals (Sweden)

    Wenbo Shan

    2016-08-01

    Full Text Available Cotton is the world's most important natural fiber crop. It is also a model system for studying polyploidization, genomic organization, and genome-size variation. Integrating the cytological characterization of cotton with its genetic map will be essential for understanding its genome structure and evolution, as well as for performing further genetic-map based mapping and cloning. In this study, we isolated a complete set of bacterial artificial chromosome clones anchored to each of the 52 chromosome arms of the tetraploid cotton Gossypium hirsutum. Combining these with telomere and centromere markers, we constructed a standard karyotype for the G. hirsutum inbred line TM-1. We dissected the chromosome arm localizations of the 45S and 5S rDNA and suggest a centromere repositioning event in the homoeologous chromosomes AT09 and DT09. By integrating a systematic karyotype analysis with the genetic linkage map, we observed different genome sizes and chromosomal structures between the subgenomes of the tetraploid cotton and those of its diploid ancestors. Using evidence of conserved coding sequences, we suggest that the different evolutionary paths of non-coding retrotransposons account for most of the variation in size between the subgenomes of tetraploid cotton and its diploid ancestors. These results provide insights into the cotton genome and will facilitate further genome studies in G. hirsutum.

  15. Comprehensive cytological characterization of the Gossypium hirsutum genome based on the development of a set of chromosome cytological markers

    Institute of Scientific and Technical Information of China (English)

    Wenbo; Shan; Yanqin; Jiang; Jinlei; Han; Kai; Wang

    2016-01-01

    Cotton is the world’s most important natural fiber crop. It is also a model system for studying polyploidization, genomic organization, and genome-size variation. Integrating the cytological characterization of cotton with its genetic map will be essential for understanding its genome structure and evolution, as well as for performing further genetic-map based mapping and cloning. In this study, we isolated a complete set of bacterial artificial chromosome clones anchored to each of the 52 chromosome arms of the tetraploid cotton Gossypium hirsutum. Combining these with telomere and centromere markers, we constructed a standard karyotype for the G. hirsutum inbred line TM-1. We dissected the chromosome arm localizations of the 45 S and 5S r DNA and suggest a centromere repositioning event in the homoeologous chromosomes AT09 and DT09. By integrating a systematic karyotype analysis with the genetic linkage map, we observed different genome sizes and chromosomal structures between the subgenomes of the tetraploid cotton and those of its diploid ancestors. Using evidence of conserved coding sequences, we suggest that the different evolutionary paths of non-coding retrotransposons account for most of the variation in size between the subgenomes of tetraploid cotton and its diploid ancestors. These results provide insights into the cotton genome and will facilitate further genome studies in G. hirsutum.

  16. Construction and Characterization of a Chitosan-Immobilized-Enzyme and β-Cyclodextrin-Included-Ferrocene-Based Electrochemical Biosensor for H2O2 Detection

    Directory of Open Access Journals (Sweden)

    Wenbo Dong

    2017-07-01

    Full Text Available An electrochemical detection biosensor was prepared with the chitosan-immobilized-enzyme (CTS-CAT and β-cyclodextrin-included-ferrocene (β-CD-FE complex for the determination of H2O2. Ferrocene (FE was included in β-cyclodextrin (β-CD to increase its stability. The structure of the β-CD-FE was characterized. The inclusion amount, inclusion rate, and electrochemical properties of inclusion complexes were determined to optimize the reaction conditions for the inclusion. CTS-CAT was prepared by a step-by-step immobilization method, which overcame the disadvantages of the conventional preparation methods. The immobilization conditions were optimized to obtain the desired enzyme activity. CTS-CAT/β-CD-FE composite electrodes were prepared by compositing the CTS-CAT with the β-CD-FE complex on a glassy carbon electrode and used for the electrochemical detection of H2O2. It was found that the CTS-CAT could produce a strong reduction peak current in response to H2O2 and the β-CD-FE could amplify the current signal. The peak current exhibited a linear relationship with the H2O2 concentration in the range of 1.0 × 10−7–6.0 × 10−3 mol/L. Our work provided a novel method for the construction of electrochemical biosensors with a fast response, good stability, high sensitivity, and a wide linear response range based on the composite of chitosan and cyclodextrin.

  17. Automatic sets and Delone sets

    International Nuclear Information System (INIS)

    Barbe, A; Haeseler, F von

    2004-01-01

    Automatic sets D part of Z m are characterized by having a finite number of decimations. They are equivalently generated by fixed points of certain substitution systems, or by certain finite automata. As examples, two-dimensional versions of the Thue-Morse, Baum-Sweet, Rudin-Shapiro and paperfolding sequences are presented. We give a necessary and sufficient condition for an automatic set D part of Z m to be a Delone set in R m . The result is then extended to automatic sets that are defined as fixed points of certain substitutions. The morphology of automatic sets is discussed by means of examples

  18. A revised dosimetric characterization of the model S700 electronic brachytherapy source containing an anode-centering plastic insert and other components not included in the 2006 model

    International Nuclear Information System (INIS)

    Hiatt, Jessica R.; Davis, Stephen D.; Rivard, Mark J.

    2015-01-01

    Purpose: The model S700 Axxent electronic brachytherapy source by Xoft, Inc., was characterized by Rivard et al. in 2006. Since then, the source design was modified to include a new insert at the source tip. Current study objectives were to establish an accurate source model for simulation purposes, dosimetrically characterize the new source and obtain its TG-43 brachytherapy dosimetry parameters, and determine dose differences between the original simulation model and the current model S700 source design. Methods: Design information from measurements of dissected model S700 sources and from vendor-supplied CAD drawings was used to aid establishment of an updated Monte Carlo source model, which included the complex-shaped plastic source-centering insert intended to promote water flow for cooling the source anode. These data were used to create a model for subsequent radiation transport simulations in a water phantom. Compared to the 2006 simulation geometry, the influence of volume averaging close to the source was substantially reduced. A track-length estimator was used to evaluate collision kerma as a function of radial distance and polar angle for determination of TG-43 dosimetry parameters. Results for the 50 kV source were determined every 0.1 cm from 0.3 to 15 cm and every 1° from 0° to 180°. Photon spectra in water with 0.1 keV resolution were also obtained from 0.5 to 15 cm and polar angles from 0° to 165°. Simulations were run for 10 10 histories, resulting in statistical uncertainties on the transverse plane of 0.04% at r = 1 cm and 0.06% at r = 5 cm. Results: The dose-rate distribution ratio for the model S700 source as compared to the 2006 model exceeded unity by more than 5% for roughly one quarter of the solid angle surrounding the source, i.e., θ ≥ 120°. The radial dose function diminished in a similar manner as for an 125 I seed, with values of 1.434, 0.636, 0.283, and 0.0975 at 0.5, 2, 5, and 10 cm, respectively. The radial dose function

  19. A revised dosimetric characterization of the model S700 electronic brachytherapy source containing an anode-centering plastic insert and other components not included in the 2006 model

    Energy Technology Data Exchange (ETDEWEB)

    Hiatt, Jessica R. [Department of Radiation Oncology, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903 (United States); Davis, Stephen D. [Department of Medical Physics, McGill University Health Centre, Montreal, Quebec H3G 1A4 (Canada); Rivard, Mark J., E-mail: mark.j.rivard@gmail.com [Department of Radiation Oncology, Tufts University School of Medicine, Boston, Massachusetts 02111 (United States)

    2015-06-15

    Purpose: The model S700 Axxent electronic brachytherapy source by Xoft, Inc., was characterized by Rivard et al. in 2006. Since then, the source design was modified to include a new insert at the source tip. Current study objectives were to establish an accurate source model for simulation purposes, dosimetrically characterize the new source and obtain its TG-43 brachytherapy dosimetry parameters, and determine dose differences between the original simulation model and the current model S700 source design. Methods: Design information from measurements of dissected model S700 sources and from vendor-supplied CAD drawings was used to aid establishment of an updated Monte Carlo source model, which included the complex-shaped plastic source-centering insert intended to promote water flow for cooling the source anode. These data were used to create a model for subsequent radiation transport simulations in a water phantom. Compared to the 2006 simulation geometry, the influence of volume averaging close to the source was substantially reduced. A track-length estimator was used to evaluate collision kerma as a function of radial distance and polar angle for determination of TG-43 dosimetry parameters. Results for the 50 kV source were determined every 0.1 cm from 0.3 to 15 cm and every 1° from 0° to 180°. Photon spectra in water with 0.1 keV resolution were also obtained from 0.5 to 15 cm and polar angles from 0° to 165°. Simulations were run for 10{sup 10} histories, resulting in statistical uncertainties on the transverse plane of 0.04% at r = 1 cm and 0.06% at r = 5 cm. Results: The dose-rate distribution ratio for the model S700 source as compared to the 2006 model exceeded unity by more than 5% for roughly one quarter of the solid angle surrounding the source, i.e., θ ≥ 120°. The radial dose function diminished in a similar manner as for an {sup 125}I seed, with values of 1.434, 0.636, 0.283, and 0.0975 at 0.5, 2, 5, and 10 cm, respectively. The radial dose

  20. A revised dosimetric characterization of the model S700 electronic brachytherapy source containing an anode-centering plastic insert and other components not included in the 2006 model.

    Science.gov (United States)

    Hiatt, Jessica R; Davis, Stephen D; Rivard, Mark J

    2015-06-01

    The model S700 Axxent electronic brachytherapy source by Xoft, Inc., was characterized by Rivard et al. in 2006. Since then, the source design was modified to include a new insert at the source tip. Current study objectives were to establish an accurate source model for simulation purposes, dosimetrically characterize the new source and obtain its TG-43 brachytherapy dosimetry parameters, and determine dose differences between the original simulation model and the current model S700 source design. Design information from measurements of dissected model S700 sources and from vendor-supplied CAD drawings was used to aid establishment of an updated Monte Carlo source model, which included the complex-shaped plastic source-centering insert intended to promote water flow for cooling the source anode. These data were used to create a model for subsequent radiation transport simulations in a water phantom. Compared to the 2006 simulation geometry, the influence of volume averaging close to the source was substantially reduced. A track-length estimator was used to evaluate collision kerma as a function of radial distance and polar angle for determination of TG-43 dosimetry parameters. Results for the 50 kV source were determined every 0.1 cm from 0.3 to 15 cm and every 1° from 0° to 180°. Photon spectra in water with 0.1 keV resolution were also obtained from 0.5 to 15 cm and polar angles from 0° to 165°. Simulations were run for 10(10) histories, resulting in statistical uncertainties on the transverse plane of 0.04% at r = 1 cm and 0.06% at r = 5 cm. The dose-rate distribution ratio for the model S700 source as compared to the 2006 model exceeded unity by more than 5% for roughly one quarter of the solid angle surrounding the source, i.e., θ ≥ 120°. The radial dose function diminished in a similar manner as for an (125)I seed, with values of 1.434, 0.636, 0.283, and 0.0975 at 0.5, 2, 5, and 10 cm, respectively. The radial dose function ratio between the current

  1. Styrene-spaced copolymers including anthraquinone and β-O-4 lignin model units: synthesis, characterization and reactivity under alkaline pulping conditions.

    Science.gov (United States)

    Megiatto, Jackson D; Cazeils, Emmanuel; Ham-Pichavant, Frédérique; Grelier, Stéphane; Gardrat, Christian; Castellan, Alain

    2012-05-14

    A series of random copoly(styrene)s has been synthesized via radical polymerization of functionalized anthraquinone (AQ) and β-O-4 lignin model monomers. The copolymers were designed to have a different number of styrene spacer groups between the AQ and β-O-4 lignin side chains aiming at investigating the distance effects on AQ/β-O-4 electron transfer mechanisms. A detailed molecular characterization, including techniques such as size exclusion chromatography, MALDI-TOF mass spectrometry, and (1)H, (13)C, (31)P NMR and UV-vis spectroscopies, afforded quantitative information about the composition of the copolymers as well as the average distribution of the AQ and β-O-4 groups in the macromolecular structures. TGA and DSC thermal analysis have indicated that the copolymers were thermally stable under regular pulping conditions, revealing the inertness of the styrene polymer backbone in the investigation of electron transfer mechanisms. Alkaline pulping experiments showed that close contact between the redox active side chains in the copolymers was fundamental for an efficient degradation of the β-O-4 lignin model units, highlighting the importance of electron transfer reactions in the lignin degradation mechanisms catalyzed by AQ. In the absence of glucose, AQ units oxidized phenolic β-O-4 lignin model parts, mainly by electron transfer leading to vanillin as major product. By contrast, in presence of glucose, anthrahydroquinone units (formed by reduction of AQ) reduced the quinone-methide units (issued by dehydration of phenolic β-O-4 lignin model part) mainly by electron transfer leading to guaiacol as major product. Both processes were distance dependent.

  2. Long-term effect of set potential on biocathodes in microbial fuel cells: electrochemical and phylogenetic characterization.

    Science.gov (United States)

    Xia, Xue; Sun, Yanmei; Liang, Peng; Huang, Xia

    2012-09-01

    The long-term effect of set potential on oxygen reducing biocathodes was investigated in terms of electrochemical and biological characteristics. Three biocathodes were poised at 200, 60 and -100 mV vs. saturated calomel electrode (SCE) for 110 days, including the first 17 days for startup. Electrochemical analyses showed that 60 mV was the optimum potential during long-term operation. The performance of all the biocathodes kept increasing after startup, suggesting a period longer than startup time needed to make potential regulation more effective. The inherent characteristics without oxygen transfer limitation were studied. Different from short-term regulation, the amounts of biomass were similar while the specific electrochemical activity was significantly influenced by potential. Moreover, potential showed a strong selection for cathode bacteria. Clones 98% similar with an uncultured Bacteroidetes bacterium clone CG84 accounted for 75% to 80% of the sequences on the biocathodes that showed higher electrochemical activity (60 and -100 mV). Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Data set characterizing the systemic alterations of microvascular reactivity and capillary density, in patients presenting with infective endocarditis.

    Science.gov (United States)

    Tibirica, Eduardo; Barcelos, Amanda; Lamas, Cristiane

    2018-06-01

    This article represents data associated with a prior publication from our research group, under the title: Evaluation of microvascular endothelial function and capillary density in patients with infective endocarditis using laser speckle contrast imaging and video-capillaroscopy [1]. Patients with definite infective endocarditis, under stable clinical conditions, were prospectively included. The clinical and laboratory features are presented for each of them in raw form. Microvascular reactivity was evaluated using a laser speckle contrast imaging (LSCI) system with a laser wavelength of 785 nm. LSCI was used in combination with the iontophoresis of acetylcholine (ACh) or sodium nitroprusside (SNP) for the noninvasive, continuous measurement of cutaneous microvascular perfusion changes in arbitrary perfusion units (APU). The images were analyzed using the manufacturer's software. One skin site on the ventral surface of the forearm was chosen for the experiment. Microvascular reactivity was also evaluated using post-occlusive reactive hyperemia, whereby arterial occlusion was achieved with supra-systolic pressure (50 mmHg above the systolic arterial pressure) using a sphygmomanometer for three minutes. Following the release of pressure, maximum flux was measured. Data on cutaneous microvascular density were obtained using intravital video-capillaroscopy. The data obtained may be helpful by showing the usefulness of laser-based noninvasive techniques in systemic infectious diseases other than sepsis, in different clinical settings and countries.

  4. Acetylated Histone H3K9 is associated with meiotic recombination hotspots, and plays a role in recombination redundantly with other factors including the H3K4 methylase Set1 in fission yeast

    Science.gov (United States)

    Yamada, Shintaro; Ohta, Kunihiro; Yamada, Takatomi

    2013-01-01

    Histone modifications are associated with meiotic recombination hotspots, discrete sites with augmented recombination frequency. For example, trimethylation of histone H3 lysine4 (H3K4me3) marks most hotspots in budding yeast and mouse. Modified histones are known to regulate meiotic recombination partly by promoting DNA double-strand break (DSB) formation at hotspots, but the role and precise landscape of involved modifications remain unclear. Here, we studied hotspot-associated modifications in fission yeast and found general features: acetylation of H3 lysine9 (H3K9ac) is elevated, and H3K4me3 is not significantly enriched. Mutating H3K9 to non-acetylatable alanine mildly reduced levels of the DSB-inducing protein Rec12 (the fission yeast homologue of Spo11) and DSB at hotspots, indicating that H3K9ac may be involved in DSB formation by enhancing the interaction between Rec12 and hotspots. In addition, we found that the lack of the H3K4 methyltransferase Set1 generally increased Rec12 binding to chromatin but partially reduced DSB formation at some loci, suggesting that Set1 is also involved in DSB formation. These results suggest that meiotic DSB formation is redundantly regulated by multiple chromatin-related factors including H3K9ac and Set1 in fission yeast. PMID:23382177

  5. {sup 13}C-METHYL FORMATE: OBSERVATIONS OF A SAMPLE OF HIGH-MASS STAR-FORMING REGIONS INCLUDING ORION-KL AND SPECTROSCOPIC CHARACTERIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Favre, Cécile; Bergin, Edwin A.; Crockett, Nathan R.; Neill, Justin L. [Department of Astronomy, University of Michigan, 500 Church Street, Ann Arbor, MI 48109 (United States); Carvajal, Miguel [Dpto. Física Aplicada, Unidad Asociada CSIC, Facultad de Ciencias Experimentales, Universidad de Huelva, E-21071 Huelva (Spain); Field, David [Department of Physics and Astronomy, University of Aarhus, Ny Munkegade 120, DK-8000 Aarhus C (Denmark); Jørgensen, Jes K.; Bisschop, Suzanne E. [Centre for Star and Planet Formation, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen Ø (Denmark); Brouillet, Nathalie; Despois, Didier; Baudry, Alain [Univ. Bordeaux, LAB, UMR 5804, F-33270, Floirac (France); Kleiner, Isabelle [Laboratoire Interuniversitaire des Systèmes Atmosphériques (LISA), CNRS, UMR 7583, Université de Paris-Est et Paris Diderot, 61, Av. du Général de Gaulle, F-94010 Créteil Cedex (France); Margulès, Laurent; Huet, Thérèse R.; Demaison, Jean, E-mail: cfavre@umich.edu, E-mail: miguel.carvajal@dfa.uhu.es [Laboratoire de Physique des Lasers, Atomes et Molécules, UMR CNRS 8523, Université Lille I, F-59655 Villeneuve d' Ascq Cedex (France)

    2015-01-01

    We have surveyed a sample of massive star-forming regions located over a range of distances from the Galactic center for methyl formate, HCOOCH{sub 3}, and its isotopologues H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3}. The observations were carried out with the APEX telescope in the frequency range 283.4-287.4 GHz. Based on the APEX observations, we report tentative detections of the {sup 13}C-methyl formate isotopologue HCOO{sup 13}CH{sub 3} toward the following four massive star-forming regions: Sgr B2(N-LMH), NGC 6334 IRS 1, W51 e2, and G19.61-0.23. In addition, we have used the 1 mm ALMA science verification observations of Orion-KL and confirm the detection of the {sup 13}C-methyl formate species in Orion-KL and image its spatial distribution. Our analysis shows that the {sup 12}C/{sup 13}C isotope ratio in methyl formate toward the Orion-KL Compact Ridge and Hot Core-SW components (68.4 ± 10.1 and 71.4 ± 7.8, respectively) are, for both the {sup 13}C-methyl formate isotopologues, commensurate with the average {sup 12}C/{sup 13}C ratio of CO derived toward Orion-KL. Likewise, regarding the other sources, our results are consistent with the {sup 12}C/{sup 13}C in CO. We also report the spectroscopic characterization, which includes a complete partition function, of the complex H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3} species. New spectroscopic data for both isotopomers H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3}, presented in this study, have made it possible to measure this fundamentally important isotope ratio in a large organic molecule for the first time.

  6. Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models

    Science.gov (United States)

    Hempstead, Joshua; Jones, Dustin P.; Ziouche, Abdelali; Cramer, Gwendolyn M.; Rizvi, Imran; Arnason, Stephen; Hasan, Tayyaba; Celli, Jonathan P.

    2015-05-01

    A lack of access to effective cancer therapeutics in resource-limited settings is implicated in global cancer health disparities between developed and developing countries. Photodynamic therapy (PDT) is a light-based treatment modality that has exhibited safety and efficacy in the clinic using wavelengths and irradiances achievable with light-emitting diodes (LEDs) operated on battery power. Here we assess low-cost enabling technology to extend the clinical benefit of PDT to regions with little or no access to electricity or medical infrastructure. We demonstrate the efficacy of a device based on a 635 nm high-output LED powered by three AA disposable alkaline batteries, to achieve strong cytotoxic response in monolayer and 3D cultures of A431 squamous carcinoma cells following photosensitization by administering aminolevulinic acid (ALA) to induce the accumulation of protoporphyrin IX (PpIX). Here we characterize challenges of battery-operated device performance, including battery drain and voltage stability specifically over relevant PDT dose parameters. Further motivated by the well-established capacity of PDT photosensitizers to serve as tumour-selective fluorescence contrast agents, we demonstrate the capability of a consumer smartphone with low-cost add-ons to measure concentration-dependent PpIX fluorescence. This study lays the groundwork for the on-going development of image-guided ALA-PDT treatment technologies for global health applications.

  7. Push it to the limit: Characterizing the convergence of common sequences of basis sets for intermolecular interactions as described by density functional theory

    Energy Technology Data Exchange (ETDEWEB)

    Witte, Jonathon [Department of Chemistry, University of California, Berkeley, California 94720 (United States); Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Neaton, Jeffrey B. [Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Department of Physics, University of California, Berkeley, California 94720 (United States); Kavli Energy Nanosciences Institute at Berkeley, Berkeley, California 94720 (United States); Head-Gordon, Martin, E-mail: mhg@cchem.berkeley.edu [Department of Chemistry, University of California, Berkeley, California 94720 (United States); Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States)

    2016-05-21

    With the aim of systematically characterizing the convergence of common families of basis sets such that general recommendations for basis sets can be made, we have tested a wide variety of basis sets against complete-basis binding energies across the S22 set of intermolecular interactions—noncovalent interactions of small and medium-sized molecules consisting of first- and second-row atoms—with three distinct density functional approximations: SPW92, a form of local-density approximation; B3LYP, a global hybrid generalized gradient approximation; and B97M-V, a meta-generalized gradient approximation with nonlocal correlation. We have found that it is remarkably difficult to reach the basis set limit; for the methods and systems examined, the most complete basis is Jensen’s pc-4. The Dunning correlation-consistent sequence of basis sets converges slowly relative to the Jensen sequence. The Karlsruhe basis sets are quite cost effective, particularly when a correction for basis set superposition error is applied: counterpoise-corrected def2-SVPD binding energies are better than corresponding energies computed in comparably sized Dunning and Jensen bases, and on par with uncorrected results in basis sets 3-4 times larger. These trends are exhibited regardless of the level of density functional approximation employed. A sense of the magnitude of the intrinsic incompleteness error of each basis set not only provides a foundation for guiding basis set choice in future studies but also facilitates quantitative comparison of existing studies on similar types of systems.

  8. Characterization of full set material constants of piezoelectric materials based on ultrasonic method and inverse impedance spectroscopy using only one sample.

    Science.gov (United States)

    Li, Shiyang; Zheng, Limei; Jiang, Wenhua; Sahul, Raffi; Gopalan, Venkatraman; Cao, Wenwu

    2013-09-14

    The most difficult task in the characterization of complete set material properties for piezoelectric materials is self-consistency. Because there are many independent elastic, dielectric, and piezoelectric constants, several samples are needed to obtain the full set constants. Property variation from sample to sample often makes the obtained data set lack of self-consistency. Here, we present a method, based on pulse-echo ultrasound and inverse impedance spectroscopy, to precisely determine the full set physical properties of piezoelectric materials using only one small sample, which eliminated the sample to sample variation problem to guarantee self-consistency. The method has been applied to characterize the [001] C poled Mn modified 0.27Pb(In 1/2 Nb 1/2 )O 3 -0.46Pb(Mg 1/3 Nb 2/3 )O 3 -0.27PbTiO 3 single crystal and the validity of the measured data is confirmed by a previously established method. For the inverse calculations using impedance spectrum, the stability of reconstructed results is analyzed by fluctuation analysis of input data. In contrast to conventional regression methods, our method here takes the full advantage of both ultrasonic and inverse impedance spectroscopy methods to extract all constants from only one small sample. The method provides a powerful tool for assisting novel piezoelectric materials of small size and for generating needed input data sets for device designs using finite element simulations.

  9. Rheological Characterization as an Alternative Method to Indentation for Determining the Setting Time of Restorative and Endodontic Cements

    Directory of Open Access Journals (Sweden)

    William N. Ha

    2017-12-01

    Full Text Available This study explored an alternative approach using rheology to assess setting time. The following cements were tested: ProRoot® MTA (Dentsply, Tulsa, OK, USA, Biodentine® (Septodont, Saint Maur des Fosses, France, Fuji VII®, FujiVII® EP, and Fuji IX® (from GC Corporation, Tokyo, Japan, RealSeal SE™ Sealer (SybronEndo, Amersfoort, The Netherlands, AH 26® and AH Plus (both from Dentsply DeTrey, Konstanz, Germany. Freshly mixed cements were placed into a strain-controlled rheometer (1 rad·s−1 with an applied strain of 0.01%. From measurements of elastic modulus over time, the time taken to reach 90% of the plateau elastic modulus (designated as the setting time was determined for each cement. In increasing order, the setting times were as follows: Fuji VII EP 3.3 min, Fuji VII 3.6 min, Fuji IX 3.7 min, ProRoot MTA 5.1 min, Biodentine 15.9 min, RealSeal 22.2 min, AH Plus 5933 min, and AH 26 5067 min. However, ProRoot MTA did not yield reliable results. The time to reach the 90% plateau elastic modulus correlates well with the setting time of glass ionomer cements and Biodentine. Using this approach gives much longer setting times for endodontic sealers than previously recognized.

  10. Nanoparticle Synthesis, Characterization, and Ecotoxicity: A Research-Based Set of Laboratory Experiments for a General Chemistry Course

    Science.gov (United States)

    Amaris, Zoe N.; Freitas, Daniel N.; Mac, Karen; Gerner, Kyle T.; Nameth, Catherine; Wheeler, Korin E.

    2017-01-01

    A series of laboratory experiments were developed to introduce first-year chemistry students to nanoscience through a green chemistry approach. Students made and characterized the stability of silver nanoparticles using two different methods: UV-visible spectroscopy and dynamic light scattering. They then assessed the ecotoxicity of silver…

  11. Characterization of the Embryogenic Tissue of the Norway Spruce Including a Transition Layer between the Tissue and the Culture Medium by Magnetic Resonance Imaging

    Directory of Open Access Journals (Sweden)

    Kořínek R.

    2017-02-01

    Full Text Available The paper describes the visualization of the cells (ESEs and mucilage (ECMSN in an embryogenic tissue via magnetic resonance imaging (MRI relaxometry measurement combined with the subsequent multi-parametric segmentation. The computed relaxometry maps T1 and T2 show a thin layer (transition layer between the culture medium and the embryogenic tissue. The ESEs, mucilage, and transition layer differ in their relaxation times T1 and T2; thus, these times can be used to characterize the individual parts within the embryogenic tissue. The observed mean values of the relaxation times T1 and T2 of the ESEs, mucilage, and transition layer are as follows: 1469 ± 324 and 53 ± 10 ms, 1784 ± 124 and 74 ± 8 ms, 929 ± 164 and 32 ± 4.7 ms, respectively. The multi-parametric segmentation exploiting the T1 and T2 relaxation times as a classifier shows the distribution of the ESEs and mucilage within the embryogenic tissue. The discussed T1 and T2 indicators can be utilized to characterize both the growth-related changes in an embryogenic tissue and the effect of biotic/abiotic stresses, thus potentially becoming a distinctive indicator of the state of any examined embryogenic tissue.

  12. Characterization of n-heptane as a single component Diesel surrogate fuel. EHPC test set-up implementation

    Energy Technology Data Exchange (ETDEWEB)

    Meijer, M.

    2010-06-15

    The availability of accurately measured fuel properties, during an injection event under engine relevant conditions is critical within the surrogate fuel approach. There is a need to perform in-house measurements in order to validate developed and new models. A well defined and accurately measured data-set will facilitate on-going work for sophisticated engine related in-cylinder combustion modeling. In this work pure n-heptane fuel is used as a single component surrogate fuel and is studied in a high-pressure constant volume optical test set-up. N-heptane is often used as a single component surrogate diesel fuel since it has a comparable Cetane number as European diesel. Detailed chemical-kinetic mechanisms for low-, intermediate-, and high-temperature n-heptane oxidation are available and several models exist that have sufficiently reduced dimensionality (number of species and reactions) to enable their use in CFD (Computational Fluid Mechanics) simulations. This report discusses the route and implementation to perform such an accurate and relevant n-heptane measurement series. The aim is to combine the efforts of earlier presented EHPC (Eindhoven High Pressure Cell) related work and new approaches, into the proposed surrogate fuel measurement series. The following aspects, related to the applied constant volume combustion chamber set-up, are studied and implemented: Extending the operating ranges towards relevant engine conditions; Study the accuracy and sensitivities of the different measurement steps; Implementing different optical diagnostic principles; and Implement a standardized and robust post processing routine. The different optical diagnostic principles used in this work are: high-speed Schlieren, Mie scattering and beginnings are made to implement a simultaneous LII LIF (Laser Induced Incandescence - Laser Induced Fluorescence) set-up using a new ICCD (Intensified Charge Coupled Device) camera with dual imaging feature. Combining the different

  13. Increased levels of NOTCH1, NF-kappaB, and other interconnected transcription factors characterize primitive sets of hematopoietic stem cells.

    Science.gov (United States)

    Panepucci, Rodrigo Alexandre; Oliveira, Lucila Habib B; Zanette, Dalila Luciola; Viu Carrara, Rita de Cassia; Araujo, Amélia Goes; Orellana, Maristela Delgado; Bonini de Palma, Patrícia Vianna; Menezes, Camila C B O; Covas, Dimas Tadeu; Zago, Marco Antonio

    2010-03-01

    As previously shown, higher levels of NOTCH1 and increased NF-kappaB signaling is a distinctive feature of the more primitive umbilical cord blood (UCB) CD34+ hematopoietic stem cells (HSCs), as compared to bone marrow (BM). Differences between BM and UCB cell composition also account for this finding. The CD133 marker defines a more primitive cell subset among CD34+ HSC with a proposed hemangioblast potential. To further evaluate the molecular basis related to the more primitive characteristics of UCB and CD133+ HSC, immunomagnetically purified human CD34+ and CD133+ cells from BM and UCB were used on gene expression microarrays studies. UCB CD34+ cells contained a significantly higher proportion of CD133+ cells than BM (70% and 40%, respectively). Cluster analysis showed that BM CD133+ cells grouped with the UCB cells (CD133+ and CD34+) rather than to BM CD34+ cells. Compared with CD34+ cells, CD133+ had a higher expression of many transcription factors (TFs). Promoter analysis on all these TF genes revealed a significantly higher frequency (than expected by chance) of NF-kappaB-binding sites (BS), including potentially novel NF-kappaB targets such as RUNX1, GATA3, and USF1. Selected transcripts of TF related to primitive hematopoiesis and self-renewal, such as RUNX1, GATA3, USF1, TAL1, HOXA9, HOXB4, NOTCH1, RELB, and NFKB2 were evaluated by real-time PCR and were all significantly positively correlated. Taken together, our data indicate the existence of an interconnected transcriptional network characterized by higher levels of NOTCH1, NF-kappaB, and other important TFs on more primitive HSC sets.

  14. The relationship between attendance at birth and maternal mortality rates: an exploration of United Nations' data sets including the ratios of physicians and nurses to population, GNP per capita and female literacy.

    Science.gov (United States)

    Robinson, J J; Wharrad, H

    2001-05-01

    The relationship between attendance at birth and maternal mortality rates: an exploration of United Nations' data sets including the ratios of physicians and nurses to population, GNP per capita and female literacy. This is the third and final paper drawing on data taken from United Nations (UN) data sets. The first paper examined the global distribution of health professionals (as measured by ratios of physicians and nurses to population), and its relationship to gross national product per capita (GNP) (Wharrad & Robinson 1999). The second paper explored the relationships between the global distribution of physicians and nurses, GNP, female literacy and the health outcome indicators of infant and under five mortality rates (IMR and u5MR) (Robinson & Wharrad 2000). In the present paper, the global distribution of health professionals is explored in relation to maternal mortality rates (MMRs). The proportion of births attended by medical and nonmedical staff defined as "attendance at birth by trained personnel" (physicians, nurses, midwives or primary health care workers trained in midwifery skills), is included as an additional independent variable in the regression analyses, together with the ratio of physicians and nurses to population, female literacy and GNP. To extend our earlier analyses by considering the relationships between the global distribution of health professionals (ratios of physicians and nurses to population, and the proportion of births attended by trained health personnel), GNP, female literacy and MMR. countries, regression analyses were performed using numbers of physicians, and numbers of nurses, per 1000 population, the proportion of births attended by trained health personnel, GNP per capita and female literacy as independent variables and MMRs as the dependent variable. Linear regression analyses show positive associations for MMRs and the ratios of physicians to population (73%, n=136), ratios of nurses to population (56%, n=137), and

  15. Cone penetrometer testing and discrete-depth groundwater sampling techniques: A cost-effective method of site characterization in a multiple-aquifer setting

    International Nuclear Information System (INIS)

    Zemo, D.A.; Pierce, Y.G.; Gallinatti, J.D.

    1992-01-01

    Cone penetrometer testing (CPT), combined with discrete-depth groundwater sampling methods, can reduce significantly the time and expense required to characterize large sites that have multiple aquifers. Results from the screening site characterization can be used to design and install a cost-effective monitoring well network. At a site in northern California, it was necessary to characterize the stratigraphy and the distribution of volatile organic compounds (VOCs) to a depth of 80 feet within a 1/2 mile-by-1/4-mile residential and commercial area in a complex alluvial fan setting. To expedite site characterization, a five-week field screening program was implemented that consisted of a shallow groundwater survey, CPT soundings, and discrete-depth groundwater sampling. Based on continuous lithologic information provided by the CPT soundings, four coarse-grained water-yielding sedimentary packages were identified. Eighty-three discrete-depth groundwater samples were collected using shallow groundwater survey techniques, the BAT Enviroprobe, or the QED HydroPunch 1, depending on subsurface conditions. A 20-well monitoring network was designed and installed to monitor critical points within each sedimentary package. Understanding the vertical VOC distribution and concentrations produced substantial cost savings by minimizing the number of permanent monitoring wells and reducing the number of costly conductor casings to be installed. Significant long-term cost savings will result from reduced sampling costs. Where total VOC concentrations exceeded 20 φg/l in the screening samples, a good correlation was found between the discrete-depth screening data and data from monitoring wells. Using a screening program to characterize the site before installing monitoring wells resulted in an estimated 50-percent reduction in costs for site characterization, 65-percent reduction in time for site characterization, and 50-percent reduction in long-term monitoring costs

  16. Parallel inversion of a massive ERT data set to characterize deep vadose zone contamination beneath former nuclear waste infiltration galleries at the Hanford Site B-Complex (Invited)

    Science.gov (United States)

    Johnson, T.; Rucker, D. F.; Wellman, D.

    2013-12-01

    The Hanford Site, located in south-central Washington, USA, originated in the early 1940's as part of the Manhattan Project and produced plutonium used to build the United States nuclear weapons stockpile. In accordance with accepted industrial practice of that time, a substantial portion of relatively low-activity liquid radioactive waste was disposed of by direct discharge to either surface soil or into near-surface infiltration galleries such as cribs and trenches. This practice was supported by early investigations beginning in the 1940s, including studies by Geological Survey (USGS) experts, whose investigations found vadose zone soils at the site suitable for retaining radionuclides to the extent necessary to protect workers and members of the general public based on the standards of that time. That general disposal practice has long since been discontinued, and the US Department of Energy (USDOE) is now investigating residual contamination at former infiltration galleries as part of its overall environmental management and remediation program. Most of the liquid wastes released into the subsurface were highly ionic and electrically conductive, and therefore present an excellent target for imaging by Electrical Resistivity Tomography (ERT) within the low-conductivity sands and gravels comprising Hanford's vadose zone. In 2006, USDOE commissioned a large scale surface ERT survey to characterize vadose zone contamination beneath the Hanford Site B-Complex, which contained 8 infiltration trenches, 12 cribs, and one tile field. The ERT data were collected in a pole-pole configuration with 18 north-south trending lines, and 18 east-west trending lines ranging from 417m to 816m in length. The final data set consisted of 208,411 measurements collected on 4859 electrodes, covering an area of 600m x 600m. Given the computational demands of inverting this massive data set as a whole, the data were initially inverted in parts with a shared memory inversion code, which

  17. Characterization of natural anaerobic dechlorination of TCE and 1,1,1-TCA in clay till including isotope fractionation and molecular biological tools

    DEFF Research Database (Denmark)

    Damgaard, Ida; Bælum, J.; Hunkeler, D.

    2010-01-01

    One of the major challenges when using enhanced reductive dechlorination (ERD) as a remediation technology at clay till sites is to obtain good contact between added agents such as donor, bacteria and the contamination. It is unclear whether degradation only takes place in fractures and/or sand l...... including the location of degradation in the fracture matrix geology. An extensive field collection of cores and discrete soil sampling has been conducted and samples have been analysed using state of the art microbial and chemical tools including isotope fractionation....

  18. Characterization of the disposition of fostamatinib in Japanese subjects including pharmacokinetic assessment in dry blood spots: results from two phase I clinical studies.

    Science.gov (United States)

    Martin, Paul; Cheung, S Y Amy; Yen, Mark; Han, David; Gillen, Michael

    2016-01-01

    The aims of the present study were to characterize the pharmacokinetics of fostamatinib in two phase I studies in healthy Japanese subjects after single- and multiple-dose administration, and to evaluate the utility of dried blood spot (DBS) sampling. In study A, 40 Japanese and 16 white subjects were randomized in a double-blind parallel group study consisting of seven cohorts, which received either placebo or a fostamatinib dose between 50 and 200 mg after single and multiple dosing. Pharmacokinetics of R406 (active metabolite of fostamatinib) in plasma and urine was assessed, and safety was intensively monitored. Study B was an open-label study that assessed fostamatinib 100 and 200 mg in 24 Japanese subjects. In addition to plasma and urine sampling (as for study A), pharmacokinetics was also assessed in blood. Mean maximum plasma concentration (C max) and area under total plasma concentration–time curve (AUC) increased with increasing dose in Japanese subjects. Steady state was achieved in 5–7 days for all doses. C max and AUC were both higher in Japanese subjects administered a 150-mg single dose than in white subjects. This difference was maintained for steady state exposure by day 10. Overall, R406 blood concentrations were consistent and ∼2.5-fold higher than in plasma. Minimal (blood cells, and DBS sampling was a useful method for assessing R406 pharmacokinetics.

  19. Use of natural clays as sorbent materials for rare earth ions: Materials characterization and set up of the operative parameters.

    Science.gov (United States)

    Iannicelli-Zubiani, Elena Maria; Cristiani, Cinzia; Dotelli, Giovanni; Gallo Stampino, Paola; Pelosato, Renato; Mesto, Ernesto; Schingaro, Emanuela; Lacalamita, Maria

    2015-12-01

    Two mineral clays of the montmorillonite group were tested as sorbents for the removal of Rare Earths (REs) from liquid solutions. Lanthanum and neodymium model solutions were used to perform uptake tests in order to: (a) verify the clays sorption capability, (b) investigate the sorption mechanisms and (c) optimize the experimental parameters, such as contact time and pH. The desorption was also studied, in order to evaluate the feasibility of REs recovery from waters. The adsorption-desorption procedure with the optimized parameters was also tested on a leaching solution obtained by dissolution of a dismantled NdFeB magnet of a hard-disk. The clays were fully characterized after REs adsorption and desorption by means of X-ray powder diffraction (XRPD) and X-ray photoelectron spectroscopy (XPS); the liquid phase was characterized via Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) analyses. The experimental results show that both clays are able to capture and release La and Nd ions, with an ion exchange mechanism. The best total efficiency (capture ≈ 50%, release ≈ 70%) is obtained when the uptake and release processes are performed at pH=5 and pH=1 respectively; in real leached scrap solutions, the uptake is around 40% but release efficiency is strongly decreased passing from a mono-ion system to a real system (from 80% to 5%). Furthermore, a strong matrix effect is found, with the matrix largely affecting both the uptake and the release of neodymium. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Isolation and Characterization of Avian Influenza Viruses, Including Highly Pathogenic H5N1, from Poultry in Live Bird Markets in Hanoi, Vietnam, in 2001

    Science.gov (United States)

    Nguyen, Doan C.; Uyeki, Timothy M.; Jadhao, Samadhan; Maines, Taronna; Shaw, Michael; Matsuoka, Yumiko; Smith, Catherine; Rowe, Thomas; Lu, Xiuhua; Hall, Henrietta; Xu, Xiyan; Balish, Amanda; Klimov, Alexander; Tumpey, Terrence M.; Swayne, David E.; Huynh, Lien P. T.; Nghiem, Ha K.; Nguyen, Hanh H. T.; Hoang, Long T.; Cox, Nancy J.; Katz, Jacqueline M.

    2005-01-01

    Since 1997, outbreaks of highly pathogenic (HP) H5N1 and circulation of H9N2 viruses among domestic poultry in Asia have posed a threat to public health. To better understand the extent of transmission of avian influenza viruses (AIV) to humans in Asia, we conducted a cross-sectional virologic study in live bird markets (LBM) in Hanoi, Vietnam, in October 2001. Specimens from 189 birds and 18 environmental samples were collected at 10 LBM. Four influenza A viruses of the H4N6 (n = 1), H5N2 (n = 1), and H9N3 (n = 2) subtypes were isolated from healthy ducks for an isolation frequency of over 30% from this species. Two H5N1 viruses were isolated from healthy geese. The hemagglutinin (HA) genes of these H5N1 viruses possessed multiple basic amino acid motifs at the cleavage site, were HP for experimentally infected chickens, and were thus characterized as HP AIV. These HA genes shared high amino acid identities with genes of other H5N1 viruses isolated in Asia during this period, but they were genetically distinct from those of H5N1 viruses isolated from poultry and humans in Vietnam during the early 2004 outbreaks. These viruses were not highly virulent for experimentally infected ducks, mice, or ferrets. These results establish that HP H5N1 viruses with properties similar to viruses isolated in Hong Kong and mainland China circulated in Vietnam as early as 2001, suggest a common source for H5N1 viruses circulating in these Asian countries, and provide a framework to better understand the recent widespread emergence of HP H5N1 viruses in Asia. PMID:15767421

  1. Characterization of patients in the European Forsteo Observational Study (EFOS): postmenopausal women entering teriparatide treatment in a community setting

    DEFF Research Database (Denmark)

    Rajzbaum, Gerald; Jakob, Franz; Karras, Dimitrios

    2007-01-01

    OBJECTIVE: The European Forsteo Observational Study (EFOS) study was primarily designed to assess fracture incidence, degree of pain, health-related quality of life (HRQoL) and compliance in women prescribed teriparatide in a community setting. This report describes the design of the study...... deformities and 91.7% were pre-treated with bisphosphonates. HRQoL, evaluated by the health state value (HSV) (median: 0.59, Q1; Q3: 0.08; 0.71) and visual analogue scale (VAS) (median 50.0, Q1; Q3: 35.0; 69.0) status of the European quality of life questionnaire (EQ-5D) was poor. Extreme problems were...

  2. Isolation, characterization, virulence and immunogenicity testing of field isolates of Pasteurella multocida, Staphylococcus aureus, and Streptococcus agalactiae in laboratory settings.

    Science.gov (United States)

    Qudratullah; Muhammad, G; Saqib, M; Bilal, M Qamar

    2017-08-01

    The present study was designed to investigate isolation, characterization, virulence and immunogenicity testing of field isolates of Pasteurella multocida, Staphylococcus aureus, and Streptococcus agalactiae in rabbits and mice. Isolates of P. multocida, S. aureus and Str. agalactiae recovered from field cases of Hemorragic septicemia and mastitis were scrutinized for virulence/pathogenicity and immunogenicity. Mouse LD 50 of P. multocida showed that P. multocida isolate No.1 was more virulent than isolates No. 2 and 3. Virulence of isolate No.1S. aureus and Str. agalactiae revealed that 100, 80% rabbits died within 18h of inoculation. Seven-digit numerical profiles of these 4 isolates with API ® Staph test strips isolates, No.1 (6736153) showed good identification (S. aureus id=90.3%). Indirect ELISA-based serum antibody titers to P. multocida isolate No.1, S. aureus No.1, Str. agalactiae, isolate No.1 elicited high antibody titers 1.9, 1.23, 1.12 respectively. All the pathogens of Isolate No. 1 (P. multocida, S. aureus Str. agalactiae), were high antibody than others isolates. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Identification and characterization of novel ERC-55 interacting proteins: evidence for the existence of several ERC-55 splicing variants; including the cytosolic ERC-55-C.

    Science.gov (United States)

    Ludvigsen, Maja; Jacobsen, Christian; Maunsbach, Arvid B; Honoré, Bent

    2009-12-01

    ERC-55, encoded from RCN2, is localized in the ER and belongs to the CREC protein family. ERC-55 is involved in various diseases and abnormal cell behavior, however, the function is not well defined and it has controversially been reported to interact with a cytosolic protein, the vitamin D receptor. We have used a number of proteomic techniques to further our functional understanding of ERC-55. By affinity purification, we observed interaction with a large variety of proteins, including those secreted and localized outside of the secretory pathway, in the cytosol and also in various organelles. We confirm the existence of several ERC-55 splicing variants including ERC-55-C localized in the cytosol in association with the cytoskeleton. Localization was verified by immunoelectron microscopy and sub-cellular fractionation. Interaction of lactoferrin, S100P, calcyclin (S100A6), peroxiredoxin-6, kininogen and lysozyme with ERC-55 was further studied in vitro by SPR experiments. Interaction of S100P requires [Ca(2+)] of approximately 10(-7) M or greater, while calcyclin interaction requires [Ca(2+)] of >10(-5) M. Interaction with peroxiredoxin-6 is independent of Ca(2+). Co-localization of lactoferrin, S100P and calcyclin with ERC-55 in the perinuclear area was analyzed by fluorescence confocal microscopy. The functional variety of the interacting proteins indicates a broad spectrum of ERC-55 activities such as immunity, redox homeostasis, cell cycle regulation and coagulation.

  4. Computational design, construction, and characterization of a set of specificity determining residues in protein-protein interactions.

    Science.gov (United States)

    Nagao, Chioko; Izako, Nozomi; Soga, Shinji; Khan, Samia Haseeb; Kawabata, Shigeki; Shirai, Hiroki; Mizuguchi, Kenji

    2012-10-01

    Proteins interact with different partners to perform different functions and it is important to elucidate the determinants of partner specificity in protein complex formation. Although methods for detecting specificity determining positions have been developed previously, direct experimental evidence for these amino acid residues is scarce, and the lack of information has prevented further computational studies. In this article, we constructed a dataset that is likely to exhibit specificity in protein complex formation, based on available crystal structures and several intuitive ideas about interaction profiles and functional subclasses. We then defined a "structure-based specificity determining position (sbSDP)" as a set of equivalent residues in a protein family showing a large variation in their interaction energy with different partners. We investigated sequence and structural features of sbSDPs and demonstrated that their amino acid propensities significantly differed from those of other interacting residues and that the importance of many of these residues for determining specificity had been verified experimentally. Copyright © 2012 Wiley Periodicals, Inc.

  5. Production and characterization of setting hydraulic cements based on calcium phosphate; Obtencao e caracterizacao de cimentos de fosfato de calcio de pega hidraulica

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Luci C. de; Rigo, Eliana C.S.; Santos, Luis A dos; Boschi, Anselmo Ortega [Sao Carlos Univ., SP (Brazil). Dept. de Engenharia de Materiais; Carrodeguas, Raul G. [Universidad de La Habana, Habana (Cuba). Centro de Biomateriales

    1997-12-31

    Setting hydraulic cements based on calcium phosphate has risen great interest in scientific literature during recent years due to their total bio compatibility and to the fact that they harden `in situ`, providing easy handling and adaptation to the shape and dimensions of the defect which requires correction, differently from the predecessors, the calcium phosphate ceramics (Hydroxy apatite, {beta}-tri calcium phosphate, biphasic, etc) in the shape of dense or porous blocks and grains. In the work, three calcium-phosphate cement compositions were studied. The resulting compositions were characterized according to the following aspects: setting times, pH, mechanical resistance, crystalline phases, microstructure and solubility in SBF (Simulated Body Fluid). The results show a potential use for the compositions. (author) 6 figs., 4 tabs.

  6. Characterization of HIV-1 antiretroviral drug resistance after second-line treatment failure in Mali, a limited-resources setting

    Science.gov (United States)

    Maiga, Almoustapha Issiaka; Fofana, Djeneba Bocar; Cisse, Mamadou; Diallo, Fodié; Maiga, Moussa Youssoufa; Traore, Hamar Alassane; Maiga, Issouf Alassane; Sylla, Aliou; Fofana, Dionke; Taiwo, Babafemi; Murphy, Robert; Katlama, Christine; Tounkara, Anatole; Calvez, Vincent; Marcelin, Anne-Geneviève

    2012-01-01

    Objectives We describe the outcomes of second-line drug resistance profiles and predict the efficacy of drugs for third-line therapy in patients monitored without the benefit of plasma HIV-1 RNA viral load (VL) or resistance testing. Methods We recruited 106 HIV-1-infected patients after second-line treatment failure in Mali. VL was determined by the Abbott RealTime system and the resistance by the ViroSeq HIV-1 genotyping system. The resistance testing was interpreted using the latest version of the Stanford algorithm. Results Among the 106 patients, 93 had isolates successfully sequenced. The median age, VL and CD4 cells were respectively 35 years, 72 000 copies/mL and 146 cells/mm3. Patients were exposed to a median of 4 years of treatment and to six antiretrovirals. We found 20% of wild-type viruses. Resistance to etravirine was noted in 38%, to lopinavir in 25% and to darunavir in 12%. The duration of prior nucleos(t)ide reverse transcriptase inhibitor exposure was associated with resistance to abacavir (P < 0.0001) and tenofovir (P = 0.0001), and duration of prior protease inhibitor treatment with resistance to lopinavir (P < 0.0001) and darunavir (P = 0.06). Conclusion Long duration of therapy prior to failure was associated with high levels of resistance and is directly related to limited access to VL monitoring and delayed switches to second-line treatment, precluding efficacy of drugs for third-line therapy. This study underlines the need for governments and public health organizations to recommend the use of VL monitoring and also the availability of darunavir and raltegravir for third-line therapies in the context of limited-resource settings. PMID:22888273

  7. Genomic characterization of two novel SAR11 isolates from the Red Sea, including the first strain of the SAR11 Ib clade.

    Science.gov (United States)

    Jimenez-Infante, Francy; Ngugi, David Kamanda; Vinu, Manikandan; Blom, Jochen; Alam, Intikhab; Bajic, Vladimir B; Stingl, Ulrich

    2017-07-01

    The SAR11 clade (Pelagibacterales) is a diverse group that forms a monophyletic clade within the Alphaproteobacteria, and constitutes up to one third of all prokaryotic cells in the photic zone of most oceans. Pelagibacterales are very abundant in the warm and highly saline surface waters of the Red Sea, raising the question of adaptive traits of SAR11 populations in this water body and warmer oceans through the world. In this study, two pure cultures were successfully obtained from surface waters on the Red Sea: one isolate of subgroup Ia and one of the previously uncultured SAR11 Ib lineage. The novel genomes were very similar to each other and to genomes of isolates of SAR11 subgroup Ia (Ia pan-genome), both in terms of gene content and synteny. Among the genes that were not present in the Ia pan-genome, 108 (RS39, Ia) and 151 genes (RS40, Ib) were strain specific. Detailed analyses showed that only 51 (RS39, Ia) and 55 (RS40, Ib) of these strain-specific genes had not reported before on genome fragments of Pelagibacterales. Further analyses revealed the potential production of phosphonates by some SAR11 members and possible adaptations for oligotrophic life, including pentose sugar utilization and adhesion to marine particulate matter. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  8. Karyotype characterization of Mugil incilis Hancock, 1830 (Mugiliformes: Mugilidae, including a description of an unusual co-localization of major and minor ribosomal genes in the family

    Directory of Open Access Journals (Sweden)

    Anne Kathrin Hett

    Full Text Available This study reports the description of the karyotype of Mugil incilis from Venezuela. The chromosome complement is composed of 48 acrocentric chromosomes, which uniformly decrease in size. Therefore, the homologues can not be clearly identified, with the exception of one of the largest chromosome pairs, classified as number 1, whose homologues may show a subcentromeric secondary constriction, and of chromosome pair number 24, which is considerably smaller than the others. C-banding showed heterochromatic blocks at the centromeric/pericentromeric regions of all chromosomes, which were more conspicuous on chromosomes 1, given the C-positive signals include the secondary constrictions. AgNO3 and fluorescent in situ hybridization (FISH with 45S rDNA demonstrated that the nucleolus organizer regions are indeed located on the secondary constrictions of chromosome pair number 1. FISH with 5S rDNA revealed that the minor ribosomal genes are located on this same chromosome pair, near the NORs, though signals are closer to the centromeres and of smaller size, compared to those of the major ribosomal gene clusters. This is the first description of co-localization of major and minor ribosomal genes in the family. Data are discussed from a cytotaxonomic and phylogenetic perspective.

  9. Genomic Characterization of Two Novel SAR11 Isolates From the Red Sea, Including the First Strain of the SAR11 Ib clade

    KAUST Repository

    Jimenez Infante, Francy M.

    2017-06-22

    The SAR11 clade (Pelagibacterales) is a diverse group that forms a monophyletic clade within the Alphaproteobacteria, and constitutes up to one third of all prokaryotic cells in the photic zone of most oceans. Pelagibacterales are very abundant in the warm and highly saline surface waters of the Red Sea, raising the question of adaptive traits of SAR11 populations in this water body and warmer oceans through the world. In this study, two pure cultures were successfully obtained from surface waters on the Red Sea, one isolate of subgroup Ia and one of the previously uncultured SAR11 Ib lineage. The novel genomes were very similar to each other and to genomes of isolates of SAR11 subgroup Ia (Ia pan-genome), both in terms of gene content and synteny. Among the genes that were not present in the Ia pan-genome, 108 (RS39, Ia) and 151 genes (RS40, Ib) were strain-specific. Detailed analyses showed that only 51 (RS39, Ia) and 55 (RS40, Ib) of these strain-specific genes had not reported before on genome fragments of Pelagibacterales. Further analyses revealed the potential production of phosphonates by some SAR11 members and possible adaptations for oligotrophic life, including pentose sugar utilization and adhesion to marine particulate matter.

  10. Genomic Characterization of Two Novel SAR11 Isolates From the Red Sea, Including the First Strain of the SAR11 Ib clade

    KAUST Repository

    Jimenez Infante, Francy M.; Ngugi, David; Vinu, Manikandan; Blom, Jochen; Alam, Intikhab; Bajic, Vladimir B.; Stingl, Ulrich

    2017-01-01

    The SAR11 clade (Pelagibacterales) is a diverse group that forms a monophyletic clade within the Alphaproteobacteria, and constitutes up to one third of all prokaryotic cells in the photic zone of most oceans. Pelagibacterales are very abundant in the warm and highly saline surface waters of the Red Sea, raising the question of adaptive traits of SAR11 populations in this water body and warmer oceans through the world. In this study, two pure cultures were successfully obtained from surface waters on the Red Sea, one isolate of subgroup Ia and one of the previously uncultured SAR11 Ib lineage. The novel genomes were very similar to each other and to genomes of isolates of SAR11 subgroup Ia (Ia pan-genome), both in terms of gene content and synteny. Among the genes that were not present in the Ia pan-genome, 108 (RS39, Ia) and 151 genes (RS40, Ib) were strain-specific. Detailed analyses showed that only 51 (RS39, Ia) and 55 (RS40, Ib) of these strain-specific genes had not reported before on genome fragments of Pelagibacterales. Further analyses revealed the potential production of phosphonates by some SAR11 members and possible adaptations for oligotrophic life, including pentose sugar utilization and adhesion to marine particulate matter.

  11. Characterization of chickpea germplasm conserved in the Indian National Genebank and development of a core set using qualitative and quantitative trait data

    Directory of Open Access Journals (Sweden)

    Sunil Archak

    2016-10-01

    Full Text Available Chickpea is the third most important pulse crop as a source of dietary protein. Ever-increasing demand in Asian countries calls for breeding superior desi-type varieties, in turn necessitating the availability of characterized germplasm to breeders. The Indian National Genebank, located at the National Bureau of Plant Genetic Resources, New Delhi, conserves 14,651 accessions of chickpea. The entire set was characterized in a single large-scale experiment. High variation was observed for eight quantitative and 12 qualitative agro-morphological traits. Allelic richness procedure was employed to assemble a core set comprising 1103 accessions, 70.0% of which were of Indian origin. Comparable values of total variation explained by the first three principal components in the entire collection (51.1% and the core (52.4% together with conservation of nine pairwise r values among quantitative traits in the core collection and a coincidence rate around 99.7% indicated that the chickpea core was indeed an excellent representation of the entire chickpea collection in the National Genebank. The chickpea core exhibited greater diversity than the entire collection in agro-morphological traits, as assessed by higher variance and Shannon–Weaver diversity indices, indicating that the chickpea core maximized the phenotypic diversity available in the Indian chickpea germplasm. The chickpea core, comprising mainly indigenous desi genotypes, is expected to be an excellent resource for chickpea breeders. Information on the chickpea core can be accessed at http://www.nbpgr.ernet.in/pgrportal.

  12. An experimental palladium-103 seed (OptiSeedexp) in a biocompatible polymer without a gold marker: Characterization of dosimetric parameters including the interseed effect

    International Nuclear Information System (INIS)

    Abboud, F.; Scalliet, P.; Vynckier, S.

    2008-01-01

    Permanent implantation of 125 I (iodine) or 103 Pd (palladium) sources is a popular treatment option in the management of early stage prostate cancer. New sources are being developed, some of which are being marketed for different clinical applications. A new technique of adjuvant stereotactic permanent seed breast implant, similar to that used in the treatment of prostate cancer, has been proposed by [N. Jansen et al., Int. J. Radiat. Oncol. Biol. Phys. 67, 1052-1058 (2007)] with encouraging results. The presence of artifacts from the metallic seeds, however, can disturb follow-up imaging. The development of plastic seeds has reduced these artifacts. This paper presents a feasibility study of the advantages of palladium-103 seeds, encapsulated with a biocompatible polymer, for future clinical applications, and on the effect of the gold marker on the dosimetric characteristics of such seeds. Experimental palladium seeds, OptiSeed exp , were manufactured by International Brachytherapy (IBt), Seneffe, Belgium, from a biocompatible polymer, including the marker. Apart from the absence of a gold marker, the studied seed has an identical design to the OptiSeed 103 [Phys. Med. Biol. 50, 1493-1504 (2005)]; [Appl. Radiat. Isot. 63, 311-321 (2005)]. Polymer encapsulation was preferred by IBt in order to reduce the quantity of radioactive material needed for a given dose rate and to reduce the anisotropy of the radiation field around the seed. In addition, this design is intended to decrease the interseed effects that can occur as a result of the marker and the encapsulation. Dosimetric measurements were performed using LiF thermoluminescent dosimeters (1 mm 3 ) in solid water phantoms (WT1). Measured data were compared to Monte Carlo simulated data in solid water using the MCNP code, version 4C. Updated cross sections [Med. Phys. 30, 701-711 (2003)] were used. As the measured and calculated data were in agreement, Monte Carlo calculations were then performed in liquid water

  13. Karyotype characterization of Mugil incilis Hancock, 1830 (Mugiliformes: Mugilidae, including a description of an unusual co-localization of major and minor ribosomal genes in the family

    Directory of Open Access Journals (Sweden)

    Anne Kathrin Hett

    2011-03-01

    Full Text Available This study reports the description of the karyotype of Mugil incilis from Venezuela. The chromosome complement is composed of 48 acrocentric chromosomes, which uniformly decrease in size. Therefore, the homologues can not be clearly identified, with the exception of one of the largest chromosome pairs, classified as number 1, whose homologues may show a subcentromeric secondary constriction, and of chromosome pair number 24, which is considerably smaller than the others. C-banding showed heterochromatic blocks at the centromeric/pericentromeric regions of all chromosomes, which were more conspicuous on chromosomes 1, given the C-positive signals include the secondary constrictions. AgNO3 and fluorescent in situ hybridization (FISH with 45S rDNA demonstrated that the nucleolus organizer regions are indeed located on the secondary constrictions of chromosome pair number 1. FISH with 5S rDNA revealed that the minor ribosomal genes are located on this same chromosome pair, near the NORs, though signals are closer to the centromeres and of smaller size, compared to those of the major ribosomal gene clusters. This is the first description of co-localization of major and minor ribosomal genes in the family. Data are discussed from a cytotaxonomic and phylogenetic perspective.Se presenta la primera descripción del cariotipo de Mugil incilis de Venezuela. El complemento cromosómico está compuesto por 48 cromosomas acrocéntricos uniformemente decrecientes en tamaño. Por lo tanto, los homólogos no pueden ser claramente identificados, con excepción de uno de los pares de mayor tamaño, clasificado como número 1, cuyos homólogos poseen una constricción secundaria subcentromérica, y el par de cromosomas número 24, considerablemente más pequeño que los otros. El bandeo-C reveló bloques heterocromáticos en las regiones centroméricas/pericentroméricas de todos los cromosomas, más conspicuas en el cromosoma 1 en el que las señales C

  14. Contribution of the geophysical and radon techniques to characterize hydrogeological setting in the western volcanic zone of Yarmouk basin: Case study Deir El-Adas

    International Nuclear Information System (INIS)

    Al-Fares, W.; Soliman, E.; Al-Ali, A.

    2009-01-01

    The aim of this study is to illustrate the geophysical and radon techniques in characterizing ''at local scale'' a hydrogeological setting in the volcanic zone of Yarmouk basin. And to employ the obtained results to understand and explain similar hydrogeological situation related to particular subsurface geologic and tectonic structure. Based on the field observations and failed wells drilled at Deir El-Adas, and the occurrence of successful well out of that zone, all these reasons, have given us the incentive to verify and provide realistic explanation of this phenomena in the basaltic outcrops of Yarmouk basin. The interpretation of the vertical electrical surveys (VES), indicates to the presence of local faulted anticline structure of Palaeogene located under the volcanic outcrops. This structure has led to complex hydrogeological conditions, represented by limited recharge in this area which occurs through fractures and secondary faults in addition to the low direct precipitation. Piezometric map indicates to water divide in the north-west of Deir El-Adas related to the tectonic setting. Meanwhile, discharge map show low reproducibility of drilled wells in Deir El-Adas and its periphery. Due to limited radon data, it was difficult to draw concrete conclusions from this technique. (author)

  15. Deep groundwater flow systems and their characterization in single-well settings by ''push-pull'' tracer tests

    International Nuclear Information System (INIS)

    Hebig-Schubert, Klaus

    2014-01-01

    This thesis demonstrates the growing importance of deep groundwater research and the increasing demand for the development of suitable single-well test methods. At the forefront of the research on groundwater in the deep underground, radioactive waste disposal in deep geological repositories, CO 2 storage, geothermal energy supply, and aquifer storage and recovery systems (ASR) are on the agenda. The developments of suitable methods for investigating these resources are a main target. Currently available methods show considerable limitations. Accordingly, comprehensive methods for the hydraulic and hydrochemical characterization of deeper aquifers with single-well access are needed. Therefore, the goal of this PhD thesis was to identify, test, and enhance potentially suitable single-well methods for characterization of groundwater flow and solute transport in such settings. For this, several Single-Well Injection-Withdrawal (''push-pull'') tracer tests were applied at the Hamasato field site (Horonobe, Japan) in a ∝100 m deep groundwater monitoring well. Aim was to characterize the impact of a dynamic saltwater-freshwater interface on a coastal aquifer. Based on the experiences of the first methodological test, a second field campaign was conducted. This campaign focused on a systematic evaluation of the push-pull tracer test method for the first time at all. The experiments focused on the investigation of the so-called ''chaser'' and its impact on the test results. The chaser is a specific part of many push-pull tracer tests setups. From these experiments, a specific test design for the investigation of the saltwater-freshwater interface in a single-well setting was developed. The application of this design on questions regarding different fluids within the same system, e.g. different mineralized fluids (saltwater-freshwater-interface, ASR) or temperatures (geothermal research), are promising future approaches for this

  16. Deep groundwater flow systems and their characterization in single-well settings by ''push-pull'' tracer tests

    Energy Technology Data Exchange (ETDEWEB)

    Hebig-Schubert, Klaus

    2014-11-21

    This thesis demonstrates the growing importance of deep groundwater research and the increasing demand for the development of suitable single-well test methods. At the forefront of the research on groundwater in the deep underground, radioactive waste disposal in deep geological repositories, CO{sub 2} storage, geothermal energy supply, and aquifer storage and recovery systems (ASR) are on the agenda. The developments of suitable methods for investigating these resources are a main target. Currently available methods show considerable limitations. Accordingly, comprehensive methods for the hydraulic and hydrochemical characterization of deeper aquifers with single-well access are needed. Therefore, the goal of this PhD thesis was to identify, test, and enhance potentially suitable single-well methods for characterization of groundwater flow and solute transport in such settings. For this, several Single-Well Injection-Withdrawal (''push-pull'') tracer tests were applied at the Hamasato field site (Horonobe, Japan) in a ∝100 m deep groundwater monitoring well. Aim was to characterize the impact of a dynamic saltwater-freshwater interface on a coastal aquifer. Based on the experiences of the first methodological test, a second field campaign was conducted. This campaign focused on a systematic evaluation of the push-pull tracer test method for the first time at all. The experiments focused on the investigation of the so-called ''chaser'' and its impact on the test results. The chaser is a specific part of many push-pull tracer tests setups. From these experiments, a specific test design for the investigation of the saltwater-freshwater interface in a single-well setting was developed. The application of this design on questions regarding different fluids within the same system, e.g. different mineralized fluids (saltwater-freshwater-interface, ASR) or temperatures (geothermal research), are promising future approaches for

  17. Construction of a complete set of alien chromosome addition lines from Gossypium australe in Gossypium hirsutum: morphological, cytological, and genotypic characterization.

    Science.gov (United States)

    Chen, Yu; Wang, Yingying; Wang, Kai; Zhu, Xiefei; Guo, Wangzhen; Zhang, Tianzhen; Zhou, Baoliang

    2014-05-01

    We report the first complete set of alien addition lines of G. hirsutum . The characterized lines can be used to introduce valuable traits from G. australe into cultivated cotton. Gossypium australe is a diploid wild cotton species (2n = 26, GG) native to Australia that possesses valuable characteristics unavailable in the cultivated cotton gene pool, such as delayed pigment gland morphogenesis in the seed and resistances to pests and diseases. However, it is very difficult to directly transfer favorable traits into cultivated cotton through conventional gene recombination due to the absence of pairing and crossover between chromosomes of G. australe and Gossypium hirsutum (2n = 52, AADD). To enhance the transfer of favorable genes from wild species into cultivated cotton, we developed a set of hirsutum-australe monosomic alien chromosome addition lines (MAAL) using a combination of morphological survey, microsatellite marker-assisted selection, and molecular cytogenetic analysis. The amphidiploid (2n = 78, AADDGG) of G. australe and G. hirsutum was consecutively backcrossed with upland cotton to develop alien addition lines of individual G. australe chromosomes in G. hirsutum. From these backcross progeny, we generated the first complete set of chromosome addition lines in cotton; 11 of 13 lines are monosomic additions, and chromosomes 7G(a) and 13G(a) are multiple additions. MAALs of 1G(a) and 11G(a) were the first to be isolated. The chromosome addition lines can be employed as bridges for the transfer of desired genes from G. australe into G. hirsutum, as well as for gene assignment, isolation of chromosome-specific probes, flow sorting and microdissection of chromosome, development of chromosome-specific ''paints'' for fluorochrome-labeled DNA fragments, physical mapping, and selective isolation and mapping of cDNAs for a particular G. australe chromosome.

  18. Validation of an air–liquid interface toxicological set-up using Cu, Pd, and Ag well-characterized nanostructured aggregates and spheres

    International Nuclear Information System (INIS)

    Svensson, C. R.; Ameer, S. S.; Ludvigsson, L.; Ali, N.; Alhamdow, A.; Messing, M. E.; Pagels, J.; Gudmundsson, A.; Bohgard, M.; Sanfins, E.; Kåredal, M.; Broberg, K.; Rissler, J.

    2016-01-01

    Systems for studying the toxicity of metal aggregates on the airways are normally not suited for evaluating the effects of individual particle characteristics. This study validates a set-up for toxicological studies of metal aggregates using an air–liquid interface approach. The set-up used a spark discharge generator capable of generating aerosol metal aggregate particles and sintered near spheres. The set-up also contained an exposure chamber, The Nano Aerosol Chamber for In Vitro Toxicity (NACIVT). The system facilitates online characterization capabilities of mass mobility, mass concentration, and number size distribution to determine the exposure. By dilution, the desired exposure level was controlled. Primary and cancerous airway cells were exposed to copper (Cu), palladium (Pd), and silver (Ag) aggregates, 50–150 nm in median diameter. The aggregates were composed of primary particles <10 nm in diameter. For Cu and Pd, an exposure of sintered aerosol particles was also produced. The doses of the particles were expressed as particle numbers, masses, and surface areas. For the Cu, Pd, and Ag aerosol particles, a range of mass surface concentrations on the air–liquid interface of 0.4–10.7, 0.9–46.6, and 0.1–1.4 µg/cm"2, respectively, were achieved. Viability was measured by WST-1 assay, cytokines (Il-6, Il-8, TNF-a, MCP) by Luminex technology. Statistically significant effects and dose response on cytokine expression were observed for SAEC cells after exposure to Cu, Pd, or Ag particles. Also, a positive dose response was observed for SAEC viability after Cu exposure. For A549 cells, statistically significant effects on viability were observed after exposure to Cu and Pd particles. The set-up produced a stable flow of aerosol particles with an exposure and dose expressed in terms of number, mass, and surface area. Exposure-related effects on the airway cellular models could be asserted.Graphical Abstract

  19. Validation of an air–liquid interface toxicological set-up using Cu, Pd, and Ag well-characterized nanostructured aggregates and spheres

    Energy Technology Data Exchange (ETDEWEB)

    Svensson, C. R., E-mail: christian.svensson@design.lth.se [Lund University, Department of Design Sciences, Ergonomics and Aerosol Technology (Sweden); Ameer, S. S. [Lund University, Division of Occupational and Environmental Medicine, Department of Laboratory Medicine (Sweden); Ludvigsson, L. [Lund University, Department of Physics, Solid State Physics (Sweden); Ali, N.; Alhamdow, A. [Lund University, Division of Occupational and Environmental Medicine, Department of Laboratory Medicine (Sweden); Messing, M. E. [Lund University, Department of Physics, Solid State Physics (Sweden); Pagels, J.; Gudmundsson, A.; Bohgard, M. [Lund University, Department of Design Sciences, Ergonomics and Aerosol Technology (Sweden); Sanfins, E. [Atomic Energy Commission (CEA), Institute of Emerging Diseases and Innovative Therapies (iMETI), Division of Prions and Related Diseases - SEPIA (France); Kåredal, M.; Broberg, K. [Lund University, Division of Occupational and Environmental Medicine, Department of Laboratory Medicine (Sweden); Rissler, J. [Lund University, Department of Design Sciences, Ergonomics and Aerosol Technology (Sweden)

    2016-04-15

    Systems for studying the toxicity of metal aggregates on the airways are normally not suited for evaluating the effects of individual particle characteristics. This study validates a set-up for toxicological studies of metal aggregates using an air–liquid interface approach. The set-up used a spark discharge generator capable of generating aerosol metal aggregate particles and sintered near spheres. The set-up also contained an exposure chamber, The Nano Aerosol Chamber for In Vitro Toxicity (NACIVT). The system facilitates online characterization capabilities of mass mobility, mass concentration, and number size distribution to determine the exposure. By dilution, the desired exposure level was controlled. Primary and cancerous airway cells were exposed to copper (Cu), palladium (Pd), and silver (Ag) aggregates, 50–150 nm in median diameter. The aggregates were composed of primary particles <10 nm in diameter. For Cu and Pd, an exposure of sintered aerosol particles was also produced. The doses of the particles were expressed as particle numbers, masses, and surface areas. For the Cu, Pd, and Ag aerosol particles, a range of mass surface concentrations on the air–liquid interface of 0.4–10.7, 0.9–46.6, and 0.1–1.4 µg/cm{sup 2}, respectively, were achieved. Viability was measured by WST-1 assay, cytokines (Il-6, Il-8, TNF-a, MCP) by Luminex technology. Statistically significant effects and dose response on cytokine expression were observed for SAEC cells after exposure to Cu, Pd, or Ag particles. Also, a positive dose response was observed for SAEC viability after Cu exposure. For A549 cells, statistically significant effects on viability were observed after exposure to Cu and Pd particles. The set-up produced a stable flow of aerosol particles with an exposure and dose expressed in terms of number, mass, and surface area. Exposure-related effects on the airway cellular models could be asserted.Graphical Abstract.

  20. Aerial Photography and Imagery, Ortho-Corrected, This data set includes georectified, 4 -band digital orthophotos for 213.7 square miles of the Blackwater National Wildlife Refuge and Fishing Bay WMA in Dorchester County, MD., Published in 2010, 1:2400 (1in=200ft) scale, Eastern Shore Regional GIS Cooperative.

    Data.gov (United States)

    NSGIC Regional | GIS Inventory — Aerial Photography and Imagery, Ortho-Corrected dataset current as of 2010. This data set includes georectified, 4 -band digital orthophotos for 213.7 square miles...

  1. Fire Stations, LAGIC is consulting with local parish GIS departments to create spatially accurate point and polygons data sets including the locations and building footprints of schools, churches, government buildings, law enforcement and emergency response offices, pha, Published in 2011, 1:12000 (1in=1000ft) scale, LSU Louisiana Geographic Information Center (LAGIC).

    Data.gov (United States)

    NSGIC Education | GIS Inventory — Fire Stations dataset current as of 2011. LAGIC is consulting with local parish GIS departments to create spatially accurate point and polygons data sets including...

  2. Grocery Stores, LAGIC is consulting with local parish GIS departments to create spatially accurate point and polygons data sets including the locations and building footprints of schools, churches, government buildings, law enforcement and emergency response offices, pha, Published in 2011, 1:12000 (1in=1000ft) scale, LSU Louisiana Geographic Information Center (LAGIC).

    Data.gov (United States)

    NSGIC Education | GIS Inventory — Grocery Stores dataset current as of 2011. LAGIC is consulting with local parish GIS departments to create spatially accurate point and polygons data sets including...

  3. Libraries, LAGIC is consulting with local parish GIS departments to create spatially accurate point and polygons data sets including the locations and building footprints of schools, churches, government buildings, law enforcement and emergency response offices, pha, Published in 2011, 1:12000 (1in=1000ft) scale, LSU Louisiana Geographic Information Center (LAGIC).

    Data.gov (United States)

    NSGIC Education | GIS Inventory — Libraries dataset current as of 2011. LAGIC is consulting with local parish GIS departments to create spatially accurate point and polygons data sets including the...

  4. Parcels and Land Ownership, This data set consists of digital map files containing parcel-level cadastral information obtained from property descriptions. Cadastral features contained in the data set include real property boundary lines, rights-of-way boundaries, property dimensions, Published in Not Provided, 1:2400 (1in=200ft) scale, Racine County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Parcels and Land Ownership dataset current as of unknown. This data set consists of digital map files containing parcel-level cadastral information obtained from...

  5. Combining hydrologic and groundwater modelling to characterize a regional aquifer system within a rift setting (Gidabo River Basin, Main Ethiopian Rift)

    Science.gov (United States)

    Birk, Steffen; Mechal, Abraham; Wagner, Thomas; Dietzel, Martin; Leis, Albrecht; Winkler, Gerfried; Mogessie, Aberra

    2016-04-01

    The development of groundwater resources within the Ethiopian Rift is complicated by the strong physiographic contrasts between the rift floor and the highland and by the manifold hydrogeological setting composed of volcanic rocks of different type and age that are intersected by numerous faults. Hydrogeochemical and isotope data from various regions within the Ethiopian Rift suggest that the aquifers within the semi-arid rift floor receive a significant contribution of groundwater flow from the humid highland. For example, the major ion composition of groundwater samples from Gidabo River Basin (3302 km²) in the southern part of the Main Ethiopian Rift reveals a mixing trend from the highland toward the rift floor; moreover, the stable isotopes of water, deuterium and O-18, of the rift-floor samples indicate a component recharged in the highland. This work aims to assess if the hydrological and hydrogeological data available for Gidabo River Basin is consistent with these findings and to characterize the regional aquifer system within the rift setting. For this purpose, a two-step approach is employed: First, the semi-distributed hydrological model SWAT is used to obtain an estimate of the spatial and temporal distribution of groundwater recharge within the watershed; second, the numerical groundwater flow model MODFLOW is employed to infer aquifer properties and groundwater flow components. The hydrological model was calibrated and validated using discharge data from three stream gauging stations within the watershed (Mechal et al., Journal of Hydrology: Regional Studies, 2015, doi:10.1016/j.ejrh.2015.09.001). The resulting recharge distribution exhibits a strong decrease from the highland, where the mean annual recharge amounts to several hundred millimetres, to the rift floor, where annual recharge largely is around 100 mm and below. Using this recharge distribution as input, a two-dimensional steady-state groundwater flow model was calibrated to hydraulic

  6. Isotopic and hydrogeochemical characterization of high-altitude karst aquifers in complex geological settings. The Ordesa and Monte Perdido National Park (Northern Spain) case study

    Energy Technology Data Exchange (ETDEWEB)

    Lambán, L.J., E-mail: javier.lamban@igme.es [Geological Survey of Spain (IGME) (Spain); Jódar, J., E-mail: jorge.jodar@upc.edu [Department of Geotechnical Engineering and Geosciences, Technical University of Catalonia (UPC), Barcelona (Spain); Custodio, E., E-mail: emilio.custodio@upc.edu [Department of Geotechnical Engineering and Geosciences, Technical University of Catalonia (UPC), Barcelona (Spain); Soler, A., E-mail: albertsoler@ub.edu [Grup de Mineralogia Aplicada i Medi Ambient, Departament Cristal lografia Mineralogia i Dipòsits Minerals, Facultat de Geologia, Universitat de Barcelona (UB) (Spain); Sapriza, G., E-mail: g.sapriza@usask.ca [Global Institute for Water Security, National Hydrology Research Centre (Canada); Soto, R., E-mail: r.soto@igme.es [Geological Survey of Spain (IGME) (Spain)

    2015-02-15

    The Ordesa and Monte Perdido National Park, located in the Southern Pyrenees, constitutes the highest karst system in Western Europe. No previous studies regarding its geochemical and isotopic groundwater characterization are available in this area. This work presents the results of field and sampling campaigns carried out between July 2007 and September 2013. The groundwater presents high calcium bicarbonate contents due to the occurrence of upper Cretaceous and lower Paleocene–Eocene carbonate materials in the studied area. Other relevant processes include dissolution of anhydrite and/or gypsum and incongruent dissolution of Mg-limestone and dolomite. The water stable isotopes (δ{sup 18}O, δ{sup 2}H) show that the oceanic fronts from the Atlantic Ocean are responsible for the high levels of precipitation. In autumn, winter, and spring, a deuterium excess is found in the recharge water, which could be related to local atmospheric transport of low-altitude snow sublimation vapour and its later condensation on the snow surface at higher altitude, where recharge is mostly produced. The recharge zones are mainly between 2500 m and 3200 m a.s.l. The tritium content of the water suggests short groundwater transit times. The isotopic composition of dissolved sulphate points to the existence of regional fluxes mixed with local discharge in some of the springs. This work highlights the major role played by the altitude difference between the recharge and discharge zones in controlling the chemistry and the vertical variability of the isotopic composition in high-altitude karst aquifers. - Highlights: • Environmental tracers are essential to study complex alpine karst aquifers. • The long presence of snow controls the deuterium excess in groundwater. • Seasonal δD content in springs depends on gap between recharge and discharge points. • The first hydrogeological characterization of the Ordesa National Park is presented. • Sulphate content in springs comes

  7. THM large spatial-temporal model to simulate the past 2 Ma hydrogeological evolution of Paris Basin including natural tracer transport as part of site characterization for radwaste repository project Cigéo - France

    Science.gov (United States)

    Benabderrahmane, A., Sr.

    2017-12-01

    Hydrogeological site characterization for deep geological high level and intermediate level long lived radioactive waste repository cover a large time scale needed for safety analysis and calculation. Hydrogeological performance of a site relies also on the effects of geodynamic evolution as tectonic uplift, erosion/sedimentation and climate including glaciation on the groundwater flow and solute and heat transfer. Thermo-Hydro-Mechanical model of multilayered aquifer system of Paris Basin is developed to reproduce the present time flow and the natural tracer (Helium) concentration profiles based on the last 2 Ma of geodynamic evolution. Present time geological conceptual model consist of 27 layers at Paris Basin (Triassic-Tertiary) with refinement at project site scale (29 layers from Triassic to Portlandian). Target layers are the clay host formation of Callovo-Oxfrodian age (160 Ma) and the surrounding aquifer layers of Oxfordian and Dogger. Modelled processes are: groundwater flow, heat and solutes (natural tracers) transport, freezing and thawing of groundwater (expansion and retreat of permafrost), deformation of the multilayered aquifer system induced by differential tectonic uplift and the hydro-mechanical stress effect as caused by erosion of the outcropping layers. Numerical simulation considers a period from 2 Ma BP and up to the present. Transient boundary conditions are governed by geodynamic processes: (i) modification of the geometry of the basin and (ii) temperatures along the topography will change according to a series of 15 identical climate cycles with multiple permafrost (glaciation) periods. Numerical model contains 71 layers and 18 million cells. The solution procedure solves three coupled systems of equations, head, temperature and concentrations, by the use of a finite difference method, and by applying extensive parallel processing. The major modelling results related to the processes of importance for site characterization as hydraulic

  8. Preliminary characterization of an alpine karst aquifer in a complex geological setting using the KARSYS approach. Picos de Europa, North Spain

    Science.gov (United States)

    Ballesteros, Daniel; Malard, Arnauld; Jeannin, Pierre-Yves; Jiménez-Sánchez, Montserrat; García-Sansegundo, Joaquín; Meléndez, Mónica; Sendra, Gemma

    2013-04-01

    Research applied to karst aquifers linked to a homogeneous limestone in high mountain areas affected by several tectonic events is a hard task, due to methodological constraints and the uncertainties of the geological data. The KARSYS approach (Jeannin et al. 2012) is based on the combination of existing geological data and basic principles of karst hydraulic, allowing for characterizing the geometry of an aquifer considering a smaller amount of data than other methods. The Picos de Europa (North Spain) is an alpine karst massif with a surface area of 700 km2, peaks up to 2,648 m and fluvial gorges up to 2,000 m deep, including about 270 km of cave passage. The bedrock is mainly composed of Ordovician quartzite covered by massive Carboniferous limestone and is affected by two systems of thrusts and other faults. The most of the geological structures are from Variscan orogeny (Carboniferous in age), some of them could be originated or modified during the Permian-Mesozoic extensional episode, and the others were originated or reactivated during the Alpine Orogeny. Therefore, the Picos de Europa can be considered as a complex geological environment in which usual hydrogeological methods are difficult to use. The aim of this study is to characterize the geometry of the Picos de Europa aquifers applying the KARSYS approach. The approach includes: 1) the identification of aquifer and aquiclude formations; 2) the inventory of the main springs; 3) the establishment of a 3D geological model, focused on the aquifer boundaries; 4) the implementation of the hydraulic features within the 3D model and the delineation of the karst system. The main aquifer of the Picos de Europa is developed within the Carboniferous limestone and displays a complex geometry generally limited and divided into several unconfined groundwater bodies by Ordovician to Carboniferous rocks related to the thrusts. The lowest limit of the aquifer is marked by the N-dipping detachment level of the thrusts

  9. Runs 800, 813, 842 and physics runs from 18.1.77 to 21.5.77, Development of a new set-up for working line measurements including a Fast Fourier Transform Spectrum Analyser and using weak beam excitiation with broad-band noise

    CERN Document Server

    Borer, J

    1977-01-01

    Runs 800, 813, 842 and physics runs from 18.1.77 to 21.5.77, Development of a new set-up for working line measurements including a Fast Fourier Transform Spectrum Analyser and using weak beam excitiation with broad-band noise

  10. Counting SET-free sets

    OpenAIRE

    Harman, Nate

    2016-01-01

    We consider the following counting problem related to the card game SET: How many $k$-element SET-free sets are there in an $n$-dimensional SET deck? Through a series of algebraic reformulations and reinterpretations, we show the answer to this question satisfies two polynomiality conditions.

  11. Use of the International Classification of Functioning, Disability and Health Generic-30 Set for the characterization of outpatients: Italian Society of Physical and Rehabilitative Medicine Residents Section Project.

    Science.gov (United States)

    Gimigliano, Francesca; De Sire, Alessandro; Gastaldo, Marco; Maghini, Irene; Paoletta, Marco; Pasquini, Andrea; Boldrini, Paolo; Selb, Melissa; Prodinger, Birgit

    2018-06-11

    The International Classification of Functioning, Disability and Health (ICF) Generic- 30 Set (previously referred to as Rehabilitation Set) is a minimal set of ICF categories for reporting and assessing functioning and disability in clinical populations with different health conditions along the continuum of care. Recently, the Italian Society of Physical and Rehabilitation Medicine (SIMFER) developed an Italian modification of the simple and intuitive descriptions (SID) of these categories. This study was the first one to implement the use of the SID in practice. 1) To implement the use of the ICF in clinical practice and research among Italian Residents in PRM. 2) To verify if the SID made the application of ICF Generic 30 Set more user-friendly than the original descriptions. 3) To examine the prevalence of functioning problems of patients accessing Rehabilitation Services to serve as reference for the development of an ICF-based clinical data collection tool. Multicenter cross-sectional study. Italian Physical Medicine and Rehabilitation (PRM) outpatient rehabilitation services. Patients referring to Italian PRM outpatient rehabilitation services and Italian Residents in PRM. Each School of Specialization involved, randomly, received the ICF Generic-30 Set with the original descriptions or with the SID. Residents collected over a 4-month period (April-July 2016) patients data related to the ICF Generic-30 Set categories. Moreover, the residents self- assessed their difficulty in using the ICF Generic-30 Set with the original descriptions or with the SID, through a Numeric Rating Scale (NRS). Ninety-three residents collected functioning data of 864 patients (mean aged 57.7±19.3) with ICF Generic-30 Set: 304 with the original descriptions and 560 with SID. The difficulty in using the ICF Generic-30 Set with SID was rated as lower than using the original descriptions (NRS = 2.8±2.5 vs 3.5±3.1; p<0.001). The most common disease was the back pain (9.6%) and

  12. TRU Waste Inventory Collection and Work-Off Plans for the Centralization of TRU Waste Characterization/Certification at INL - On Your Mark - Get Set

    International Nuclear Information System (INIS)

    McTaggart, J.; Lott, S.

    2009-01-01

    The U.S. Department of Energy (DOE) amended the Record of Decision (ROD) for the Waste Management Program: Treatment and Storage of Transuranic Waste to centralize transuranic (TRU) waste characterization/certification from fourteen TRU waste sites. This centralization will allow for treatment, characterization and certification of TRU waste from the fourteen sites, thirteen of which are sites with small quantities of TRU waste, at the Idaho National Laboratory (INL) prior to shipping the waste to the Waste Isolation Pilot Plant (WIPP) for disposal. Centralization of this TRU waste will avoid the cost of building treatment, characterization, certification, and shipping capabilities at each of the small quantity sites that currently do not have existing facilities. Advanced Mixed Waste Treatment Project (AMWTP) and Idaho Nuclear Technology and Engineering Center (INTEC) will provide centralized shipping facilities, to WIPP, for all of the small quantity sites. Hanford, the one large quantity site identified in the ROD, has a large number of waste in containers that are over-packed into larger containers which are inefficient for shipment to and disposal at WIPP. The AMWTP at the INL will reduce the volume of much of the CH waste and make it much more efficient to ship and dispose of at WIPP. In addition, the INTEC has a certified remote handled (RH) TRU waste characterization/certification program at INL to disposition TRU waste from the sites identified in the ROD. (authors)

  13. TRU waste inventory collection and work-off plans for the centralization of TRU waste characterization at INL - on your mark - get set - 9410

    International Nuclear Information System (INIS)

    Mctaggert, Jerri Lynne; Lott, Sheila; Gadbury, Casey

    2009-01-01

    The U.S. Department of Energy (DOE) amended the Record of Decision (ROD) for the Waste Management Program: Treatment and Storage ofTransuranic Waste to centralize transuranic (TRU) waste characterization/certification from fourteen TRU waste sites. This centralization will allow for treatment, characterization and certification ofTRU waste from the fourteen sites, thirteen of which are sites with small quantities ofTRU waste, at the Idaho National Laboratory (INL) prior to shipping the waste to the Waste Isolation Pilot Plant (WIPP) for disposal. Centralization ofthis TRU waste will avoid the cost ofbuilding treatment, characterization, certification, and shipping capabilities at each ofthe small quantity sites that currently do not have existing facilities. Advanced Mixed Waste Treatment Project (AMWTP) and Idaho Nuclear Technology and Engineering Center (INTEC) will provide centralized shipping facilities, to WIPP, for all ofthe small quantity sites. Hanford, the one large quantity site identified in the ROD, has a large number ofwaste in containers that are overpacked into larger containers which are inefficient for shipment to and disposal at WIPP. The AMWTP at the INL will reduce the volume ofmuch of the CH waste and make it much more efficient to ship and dispose of at WIPP. In addition, the INTEC has a certified remote handled (RH) TRU waste characterization/certification program at INL to disposition TRU waste from the sites identified in the ROD.

  14. Identification and phenotypic characterization of a second collagen adhesin, Scm, and genome-based identification and analysis of 13 other predicted MSCRAMMs, including four distinct pilus loci, in Enterococcus faecium.

    Science.gov (United States)

    Sillanpää, Jouko; Nallapareddy, Sreedhar R; Prakash, Vittal P; Qin, Xiang; Höök, Magnus; Weinstock, George M; Murray, Barbara E

    2008-10-01

    Attention has recently been drawn to Enterococcus faecium because of an increasing number of nosocomial infections caused by this species and its resistance to multiple antibacterial agents. However, relatively little is known about the pathogenic determinants of this organism. We have previously identified a cell-wall-anchored collagen adhesin, Acm, produced by some isolates of E. faecium, and a secreted antigen, SagA, exhibiting broad-spectrum binding to extracellular matrix proteins. Here, we analysed the draft genome of strain TX0016 for potential microbial surface components recognizing adhesive matrix molecules (MSCRAMMs). Genome-based bioinformatics identified 22 predicted cell-wall-anchored E. faecium surface proteins (Fms), of which 15 (including Acm) had characteristics typical of MSCRAMMs, including predicted folding into a modular architecture with multiple immunoglobulin-like domains. Functional characterization of one [Fms10; redesignated second collagen adhesin of E. faecium (Scm)] revealed that recombinant Scm(65) (A- and B-domains) and Scm(36) (A-domain) bound to collagen type V efficiently in a concentration-dependent manner, bound considerably less to collagen type I and fibrinogen, and differed from Acm in their binding specificities to collagen types IV and V. Results from far-UV circular dichroism measurements of recombinant Scm(36) and of Acm(37) indicated that these proteins were rich in beta-sheets, supporting our folding predictions. Whole-cell ELISA and FACS analyses unambiguously demonstrated surface expression of Scm in most E. faecium isolates. Strikingly, 11 of the 15 predicted MSCRAMMs clustered in four loci, each with a class C sortase gene; nine of these showed similarity to Enterococcus faecalis Ebp pilus subunits and also contained motifs essential for pilus assembly. Antibodies against one of the predicted major pilus proteins, Fms9 (redesignated EbpC(fm)), detected a 'ladder' pattern of high-molecular-mass protein bands in a

  15. A new set of microsatellite markers for the peach palm (Bactris gasipaes Kunth): characterization and across-taxa utility within the tribe Cocoeae.

    NARCIS (Netherlands)

    Billotte, N.; Couvreur, T.L.P.; Marseillac, P.; Brottier, P.; Perthuis, B.; Vallejo, M.; Noyer, J.L.; Jacquemoud, J.P.; Risterucci, A.M.; Pintaud, J.C.

    2004-01-01

    A (GA)n microsatellite-enriched library was constructed and a new set of 18 nuclear simple sequence repeat loci was isolated in Bactris gasipaes var. gasipaes. The loci were found to be highly variable in the target species and readily transferable to related Bactris species as well as to the

  16. The Manifestation of Stopping Sets and Absorbing Sets as Deviations on the Computation Trees of LDPC Codes

    Directory of Open Access Journals (Sweden)

    Eric Psota

    2010-01-01

    Full Text Available The error mechanisms of iterative message-passing decoders for low-density parity-check codes are studied. A tutorial review is given of the various graphical structures, including trapping sets, stopping sets, and absorbing sets that are frequently used to characterize the errors observed in simulations of iterative decoding of low-density parity-check codes. The connections between trapping sets and deviations on computation trees are explored in depth using the notion of problematic trapping sets in order to bridge the experimental and analytic approaches to these error mechanisms. A new iterative algorithm for finding low-weight problematic trapping sets is presented and shown to be capable of identifying many trapping sets that are frequently observed during iterative decoding of low-density parity-check codes on the additive white Gaussian noise channel. Finally, a new method is given for characterizing the weight of deviations that result from problematic trapping sets.

  17. Data set on the characterization of the phytoestrogenic extract and isolated compounds of the roots of Inula racemosa Hook F (Asteraceae

    Directory of Open Access Journals (Sweden)

    Mangathayaru Kalachaveedu

    2018-04-01

    Full Text Available The data presented in this article are related to the research article entitled ‘ Phyto estrogenic effect of Inula racemosa Hook. f – A cardio protective root drug in traditional medicine, (Mangathayaru K, Divya R, Srivani T et al., 2018 [1]. It describes the characterization details of the root extract and the compounds isolated from them that were shown to be phytoestrogenic in vivo and in vitro respectively. Keywords: Alantolactone, Isoalantolactone, Stigmasterol glycoside, Inulin

  18. Using multiple continuous fine particle monitors to characterize tobacco, incense, candle, cooking, wood burning, and vehicular sources in indoor, outdoor, and in-transit settings

    Science.gov (United States)

    Ott, Wayne R.; Siegmann, Hans C.

    This study employed two continuous particle monitors operating on different measurement principles to measure concentrations simultaneously from common combustion sources in indoor, outdoor, and in-transit settings. The pair of instruments use (a) photo-charging (PC) operating on the principle ionization of fine particles that responds to surface particulate polycyclic aromatic hydrocarbons (PPAHs), and (b) diffusion charging (DC) calibrated to measure the active surface area of fine particles. The sources studied included: (1) secondhand smoke (cigarettes, cigars, and pipes), (2) incense (stick and cone), (3) candles used as food warmers, (4) cooking (toasting bread and frying meat), (5) fireplaces and ambient wood smoke, and (6) in-vehicle exposures traveling on California arterials and interstate highways. The ratio of the PC to the DC readings, or the PC/DC ratio, was found to be different for major categories of sources. Cooking, burning toast, and using a "canned heat" food warmer gave PC/DC ratios close to zero. Controlled experiments with 10 cigarettes averaged 0.15 ng mm -2 (ranging from 0.11 to 0.19 ng mm -2), which was similar to the PC/DC ratio for a cigar, although a pipe was slightly lower (0.09 ng mm -2). Large incense sticks had PC/DC ratios similar to those of cigarettes and cigars. The PC/DC ratios for ambient wood smoke averaged 0.29 ng mm -2 on 6 dates, or about twice those of cigarettes and cigars, reflecting a higher ratio of PAH to active surface area. The smoke from two artificial logs in a residential fireplace had a PC/DC ratio of 0.33-0.35 ng mm -2. The emissions from candles were found to vary, depending on how the candles were burned. If the candle flickered and generated soot, a higher PC/DC ratio resulted than if the candle burned uniformly in still air. Inserting piece of metal into the candle's flame caused high PPAH emissions with a record PC/DC reading of 1.8 ng mm -2. In-vehicle exposures measured on 43- and 50-min drives on a

  19. Facile synthesis and characterization of novel rapid-setting spherical sub-micron bioactive glasses cements and their biocompatibility in vitro

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yuli, E-mail: lily19791002@126.com [Plastic Surgery Institute of Weifang Medical University, Weifang Medical University, Weifang 261053 (China); National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou 510006 (China); Liang, Qiming; Lin, Cai; Li, Xian [National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou 510006 (China); Chen, Xiaofeng, E-mail: chenxf@scut.edu.cn [National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou 510006 (China); Hu, Qing, E-mail: stefan_hu@foxmail.com [School of Material Science and Engineering, Jingdezhen Ceramic Institute, Jingdezhen 333001 (China)

    2017-06-01

    Dental pulp vitality is extremely important for the tooth viability, since it provides nutrition and forms the dentin. Bioactive glasses (BGs) may be promising materials for pulp repair due to their excellent abilities of rapidly bonding to bone and stimulating new bone growth. However, the unsatisfied handling property, low plasticity, and poor rapid-setting property of traditional BGs limit its application in vital pulp therapy. Spherical bioactive glasses (SBGs) exhibited higher osteogenesis and odontogenic differentiation than irregular BGs. This study focuses on the application of SBGs with rapid setting property for dental pulp repair. Here, SBGs with various compositions were successfully synthesized by a sol-gel process using dodecylamine (DDA) served as both a catalyst and a template. The maximum content of CaO in SBGs was about 15%. The non-bridge oxygen amounts of the Si−O network and the apatite-forming ability increased with the content proportion of CaO and P{sub 2}O{sub 5}. Bioactive glass pulp capping materials (BGPCMs) were prepared by mixing the SBGs powders and the phosphate buffer solution (PBS). The K{sub 3}CaH(PO{sub 4}){sub 2} and hydroxyapatite (HA) formed between SBGs particles as soon as they were mixed with PBS solution. The compressive strengths of fully set BCPCM-2 molded were measured to be 31.76 ± 1.9577 MPa after setting for 24 h. The K{sub 3}CaH(PO{sub 4}){sub 2} and the low crystallinity HA phases at the initial stage of solidification transformed to crystalline HA for 3 days, and the compressive strength was still higher than 10 MPa. Additionally, SBG-2 with a designed molar composition of 35% SiO{sub 2}, 55% CaO and 10% P{sub 2}O{sub 5} more promoted dental pulp cell proliferation, and could be potential pulp capping applications. - Highlights: • Spherical bioactive glasses (SBGs) with the maximum content of 15 mol% CaO were successfully synthesized. • BG pulp capping materials (BGPCMs) were prepared by mixing the SBGs

  20. Quantitative characterization of metastatic disease in the spine. Part I. Semiautomated segmentation using atlas-based deformable registration and the level set method

    International Nuclear Information System (INIS)

    Hardisty, M.; Gordon, L.; Agarwal, P.; Skrinskas, T.; Whyne, C.

    2007-01-01

    Quantitative assessment of metastatic disease in bone is often considered immeasurable and, as such, patients with skeletal metastases are often excluded from clinical trials. In order to effectively quantify the impact of metastatic tumor involvement in the spine, accurate segmentation of the vertebra is required. Manual segmentation can be accurate but involves extensive and time-consuming user interaction. Potential solutions to automating segmentation of metastatically involved vertebrae are demons deformable image registration and level set methods. The purpose of this study was to develop a semiautomated method to accurately segment tumor-bearing vertebrae using the aforementioned techniques. By maintaining morphology of an atlas, the demons-level set composite algorithm was able to accurately differentiate between trans-cortical tumors and surrounding soft tissue of identical intensity. The algorithm successfully segmented both the vertebral body and trabecular centrum of tumor-involved and healthy vertebrae. This work validates our approach as equivalent in accuracy to an experienced user

  1. Development and characterization of a snapshot Mueller matrix polarimeter for the determination of cervical cancer risk in the low resource setting

    Science.gov (United States)

    Ramella-Roman, Jessica C.; Gonzalez, Mariacarla; Chue-Sang, Joseph; Montejo, Karla; Krup, Karl; Srinivas, Vijaya; DeHoog, Edward; Madhivanan, Purnima

    2018-04-01

    Mueller Matrix polarimetry can provide useful information about the function and structure of the extracellular matrix. Mueller Matrix systems are sophisticated and costly optical tools that have been used primarily in the laboratory or in hospital settings. Here we introduce a low-cost snapshot Mueller Matrix polarimeter that that does not require external power, has no moving parts, and can acquire a full Mueller Matrix in less than 50 milliseconds. We utilized this technology in the study of cervical cancer in Mysore India, yet the system could be translated in multiple diagnostic applications.

  2. New seismograph includes filters

    Energy Technology Data Exchange (ETDEWEB)

    1979-11-02

    The new Nimbus ES-1210 multichannel signal enhancement seismograph from EG and G geometrics has recently been redesigned to include multimode signal fillers on each amplifier. The ES-1210F is a shallow exploration seismograph for near subsurface exploration such as in depth-to-bedrock, geological hazard location, mineral exploration, and landslide investigations.

  3. Synthesis and characterization of mononuclear copper(II complex of tetradentate N2S2 donor set and the study of DNA and bovine serum albumin binding

    Directory of Open Access Journals (Sweden)

    Sandipan Sarkar

    2014-12-01

    Full Text Available One mononuclear copper(II complex, containing neutral tetradentate NSSN-type ligands, of formulation [Cu II(L 1Cl]ClO 4 (1, was synthesized and isolated in pure form [where L 1˭ 1,3-bis(3-pyridylmethylthiopropane]. Green-colored copper(II complex was characterized by physicochemical, spectroscopic methods and conductivity measurement. These experimental data matched well with the proposed structure of the complex. Biological activity of the complex (1 toward calf thymus DNA and bovine serum albumin has been examined systematically and groove-binding behavior of the Copper(II complex 1 with calf thymus DNA has been observed from the spectral study.

  4. A study of parameter setting and characterization of visible-light driven nitrogen-modified commercial TiO{sub 2} photocatalysts

    Energy Technology Data Exchange (ETDEWEB)

    Kuo, Yu-Lin, E-mail: ylkuo@mail.ntust.edu.tw [Department of Mechanical Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Rd., Taipei 106, Taiwan (China); Su, Te-Li [Department of Cosmetic Application and Management, St. Mary' s Medicine, Nursing and Management College, Yilan 266, Taiwan (China); Kung, Fu-Chen [Department of Health Developing and Health Marketing, Kainan University, Taoyuan County 338, Taiwan (China); Wu, Tsai-Jung [Department of Mechanical Engineering, National Taiwan University of Science and Technology, No. 43, Sec. 4, Keelung Rd., Taipei 106, Taiwan (China)

    2011-06-15

    Highlights: {yields} A cost-effective and highly-efficient visible-light driven nitrogen-modified TiO{sub 2} photocatalyst was prepared by a simple hydrolysis method. {yields} The obtained optimum conditions applied to Taguchi method for preparing visible-light driven photocatalyst were undergone by the process of stirring for 1 day using 4M ammonium as the nitrogen source, and then calcining at 400{sup Degree-Sign }C for 2 h. {yields} Several materials technologies of characterizing N-TiO2 photocatalyst have been used to realize the modification of TiO2 by ammonia water as the nitrogen source. - Abstract: An optimal condition applied to the Taguchi method with an L{sub 9} orthogonal array for preparing a visible-light driven nitrogen-modified TiO{sub 2} (N-TiO{sub 2}) photocatalyst by a simple hydrolysis method has been examined for material characteristics and a photodecolorization test of methyl blue (MB) under various visible light source (fluorescent and blue LED lamps) irradiations. Results of the material characterization showed that the absorption of prepared N-TiO{sub 2} powder exhibited a significant extension into visible light regimes with an optical bandgap (Eg) of around 2.96 eV, which subsequently improved the visible-light photocatalytic activity of N-TiO{sub 2} samples. The superior photocatalytic properties, the pseudo first-order reaction rate constants (k) and photodecolorization efficiency ({eta}%) of a N-TiO{sub 2} photocatalyst during the photodecolorization test of methyl blue (MB) under two different visible light irradiations were very evident compared to those for pure TiO{sub 2}. For photodecolorization of practical dyeing from the waste water from the dyeing and finishing industry, a higher photodecolorization efficiency of N-TiO{sub 2} powder toward Direct blue-86 (DB-86) (Direct Fast Turquoise Blue GL) dye was also achieved.

  5. A study of parameter setting and characterization of visible-light driven nitrogen-modified commercial TiO2 photocatalysts

    International Nuclear Information System (INIS)

    Kuo, Yu-Lin; Su, Te-Li; Kung, Fu-Chen; Wu, Tsai-Jung

    2011-01-01

    Highlights: → A cost-effective and highly-efficient visible-light driven nitrogen-modified TiO 2 photocatalyst was prepared by a simple hydrolysis method. → The obtained optimum conditions applied to Taguchi method for preparing visible-light driven photocatalyst were undergone by the process of stirring for 1 day using 4M ammonium as the nitrogen source, and then calcining at 400 ° C for 2 h. → Several materials technologies of characterizing N-TiO2 photocatalyst have been used to realize the modification of TiO2 by ammonia water as the nitrogen source. - Abstract: An optimal condition applied to the Taguchi method with an L 9 orthogonal array for preparing a visible-light driven nitrogen-modified TiO 2 (N-TiO 2 ) photocatalyst by a simple hydrolysis method has been examined for material characteristics and a photodecolorization test of methyl blue (MB) under various visible light source (fluorescent and blue LED lamps) irradiations. Results of the material characterization showed that the absorption of prepared N-TiO 2 powder exhibited a significant extension into visible light regimes with an optical bandgap (Eg) of around 2.96 eV, which subsequently improved the visible-light photocatalytic activity of N-TiO 2 samples. The superior photocatalytic properties, the pseudo first-order reaction rate constants (k) and photodecolorization efficiency (η%) of a N-TiO 2 photocatalyst during the photodecolorization test of methyl blue (MB) under two different visible light irradiations were very evident compared to those for pure TiO 2 . For photodecolorization of practical dyeing from the waste water from the dyeing and finishing industry, a higher photodecolorization efficiency of N-TiO 2 powder toward Direct blue-86 (DB-86) (Direct Fast Turquoise Blue GL) dye was also achieved.

  6. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.; Fratalocchi, Andrea; Totero Gongora, Juan Sebastian; Coluccio, Maria Laura; Candeloro, Patrizio; Cuda, Gianni

    2015-01-01

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  7. Saskatchewan resources. [including uranium

    Energy Technology Data Exchange (ETDEWEB)

    1979-09-01

    The production of chemicals and minerals for the chemical industry in Saskatchewan are featured, with some discussion of resource taxation. The commodities mentioned include potash, fatty amines, uranium, heavy oil, sodium sulfate, chlorine, sodium hydroxide, sodium chlorate and bentonite. Following the successful outcome of the Cluff Lake inquiry, the uranium industry is booming. Some developments and production figures for Gulf Minerals, Amok, Cenex and Eldorado are mentioned.

  8. Being Included and Excluded

    DEFF Research Database (Denmark)

    Korzenevica, Marina

    2016-01-01

    Following the civil war of 1996–2006, there was a dramatic increase in the labor mobility of young men and the inclusion of young women in formal education, which led to the transformation of the political landscape of rural Nepal. Mobility and schooling represent a level of prestige that rural...... politics. It analyzes how formal education and mobility either challenge or reinforce traditional gendered norms which dictate a lowly position for young married women in the household and their absence from community politics. The article concludes that women are simultaneously excluded and included from...... community politics. On the one hand, their mobility and decision-making powers decrease with the increase in the labor mobility of men and their newly gained education is politically devalued when compared to the informal education that men gain through mobility, but on the other hand, schooling strengthens...

  9. Characterization of mature maize (Zea mays L.) root system architecture and complexity in a diverse set of Ex-PVP inbreds and hybrids.

    Science.gov (United States)

    Hauck, Andrew L; Novais, Joana; Grift, Tony E; Bohn, Martin O

    2015-01-01

    The mature root system is a vital plant organ, which is critical to plant performance. Commercial maize (Zea mays L.) breeding has resulted in a steady increase in plant performance over time, along with noticeable changes in above ground vegetative traits, but the corresponding changes in the root system are not presently known. In this study, roughly 2500 core root systems from field trials of a set of 10 diverse elite inbreds formerly protected by Plant Variety Protection plus B73 and Mo17 and the 66 diallel intercrosses among them were evaluated for root traits using high throughput image-based phenotyping. Overall root architecture was modeled by root angle (RA) and stem diameter (SD), while root complexity, the amount of root branching, was quantified using fractal analysis to obtain values for fractal dimension (FD) and fractal abundance (FA). For each trait, per se line effects were highly significant and the most important contributor to trait performance. Mid-parent heterosis and specific combining ability was also highly significant for FD, FA, and RA, while none of the traits showed significant general combining ability. The interaction between the environment and the additive line effect was also significant for all traits. Within the inbred and hybrid generations, FD and FA were highly correlated (rp ≥ 0.74), SD was moderately correlated to FD and FA (0.69 ≥ rp ≥ 0.48), while the correlation between RA and other traits was low (0.13 ≥ rp ≥ -0.40). Inbreds with contrasting effects on complexity and architecture traits were observed, suggesting that root complexity and architecture traits are inherited independently. A more comprehensive understanding of the maize root system and the way it interacts with the environment will be useful for defining adaptation to nutrient acquisition and tolerance to stress from drought and high plant densities, critical factors in the yield gains of modern hybrids.

  10. A new set of ESTs and cDNA clones from full-length and normalized libraries for gene discovery and functional characterization in citrus

    Directory of Open Access Journals (Sweden)

    Alamar Santiago

    2009-09-01

    Full Text Available Abstract Background Interpretation of ever-increasing raw sequence information generated by modern genome sequencing technologies faces multiple challenges, such as gene function analysis and genome annotation. Indeed, nearly 40% of genes in plants encode proteins of unknown function. Functional characterization of these genes is one of the main challenges in modern biology. In this regard, the availability of full-length cDNA clones may fill in the gap created between sequence information and biological knowledge. Full-length cDNA clones facilitate functional analysis of the corresponding genes enabling manipulation of their expression in heterologous systems and the generation of a variety of tagged versions of the native protein. In addition, the development of full-length cDNA sequences has the power to improve the quality of genome annotation. Results We developed an integrated method to generate a new normalized EST collection enriched in full-length and rare transcripts of different citrus species from multiple tissues and developmental stages. We constructed a total of 15 cDNA libraries, from which we isolated 10,898 high-quality ESTs representing 6142 different genes. Percentages of redundancy and proportion of full-length clones range from 8 to 33, and 67 to 85, respectively, indicating good efficiency of the approach employed. The new EST collection adds 2113 new citrus ESTs, representing 1831 unigenes, to the collection of citrus genes available in the public databases. To facilitate functional analysis, cDNAs were introduced in a Gateway-based cloning vector for high-throughput functional analysis of genes in planta. Herein, we describe the technical methods used in the library construction, sequence analysis of clones and the overexpression of CitrSEP, a citrus homolog to the Arabidopsis SEP3 gene, in Arabidopsis as an example of a practical application of the engineered Gateway vector for functional analysis. Conclusion The new

  11. A new set of ESTs and cDNA clones from full-length and normalized libraries for gene discovery and functional characterization in citrus

    Science.gov (United States)

    Marques, M Carmen; Alonso-Cantabrana, Hugo; Forment, Javier; Arribas, Raquel; Alamar, Santiago; Conejero, Vicente; Perez-Amador, Miguel A

    2009-01-01

    Background Interpretation of ever-increasing raw sequence information generated by modern genome sequencing technologies faces multiple challenges, such as gene function analysis and genome annotation. Indeed, nearly 40% of genes in plants encode proteins of unknown function. Functional characterization of these genes is one of the main challenges in modern biology. In this regard, the availability of full-length cDNA clones may fill in the gap created between sequence information and biological knowledge. Full-length cDNA clones facilitate functional analysis of the corresponding genes enabling manipulation of their expression in heterologous systems and the generation of a variety of tagged versions of the native protein. In addition, the development of full-length cDNA sequences has the power to improve the quality of genome annotation. Results We developed an integrated method to generate a new normalized EST collection enriched in full-length and rare transcripts of different citrus species from multiple tissues and developmental stages. We constructed a total of 15 cDNA libraries, from which we isolated 10,898 high-quality ESTs representing 6142 different genes. Percentages of redundancy and proportion of full-length clones range from 8 to 33, and 67 to 85, respectively, indicating good efficiency of the approach employed. The new EST collection adds 2113 new citrus ESTs, representing 1831 unigenes, to the collection of citrus genes available in the public databases. To facilitate functional analysis, cDNAs were introduced in a Gateway-based cloning vector for high-throughput functional analysis of genes in planta. Herein, we describe the technical methods used in the library construction, sequence analysis of clones and the overexpression of CitrSEP, a citrus homolog to the Arabidopsis SEP3 gene, in Arabidopsis as an example of a practical application of the engineered Gateway vector for functional analysis. Conclusion The new EST collection denotes an

  12. The characterization of a new set of EST-derived simple sequence repeat (SSR markers as a resource for the genetic analysis of Phaseolus vulgaris

    Directory of Open Access Journals (Sweden)

    Borba Tereza CO

    2011-05-01

    Full Text Available Abstract Background Over recent years, a growing effort has been made to develop microsatellite markers for the genomic analysis of the common bean (Phaseolus vulgaris to broaden the knowledge of the molecular genetic basis of this species. The availability of large sets of expressed sequence tags (ESTs in public databases has given rise to an expedient approach for the identification of SSRs (Simple Sequence Repeats, specifically EST-derived SSRs. In the present work, a battery of new microsatellite markers was obtained from a search of the Phaseolus vulgaris EST database. The diversity, degree of transferability and polymorphism of these markers were tested. Results From 9,583 valid ESTs, 4,764 had microsatellite motifs, from which 377 were used to design primers, and 302 (80.11% showed good amplification quality. To analyze transferability, a group of 167 SSRs were tested, and the results showed that they were 82% transferable across at least one species. The highest amplification rates were observed between the species from the Phaseolus (63.7%, Vigna (25.9%, Glycine (19.8%, Medicago (10.2%, Dipterix (6% and Arachis (1.8% genera. The average PIC (Polymorphism Information Content varied from 0.53 for genomic SSRs to 0.47 for EST-SSRs, and the average number of alleles per locus was 4 and 3, respectively. Among the 315 newly tested SSRs in the BJ (BAT93 X Jalo EEP558 population, 24% (76 were polymorphic. The integration of these segregant loci into a framework map composed of 123 previously obtained SSR markers yielded a total of 199 segregant loci, of which 182 (91.5% were mapped to 14 linkage groups, resulting in a map length of 1,157 cM. Conclusions A total of 302 newly developed EST-SSR markers, showing good amplification quality, are available for the genetic analysis of Phaseolus vulgaris. These markers showed satisfactory rates of transferability, especially between species that have great economic and genomic values. Their diversity

  13. Microbiological characterization and functionality of set-type yogurt fermented with potential prebiotic substrates Cudrania tricuspidata and Morus alba L. leaf extracts.

    Science.gov (United States)

    Oh, Nam Su; Lee, Ji Young; Joung, Jae Yeon; Kim, Kyung Su; Shin, Yong Kook; Lee, Kwang-Won; Kim, Sae Hun; Oh, Sangnam; Kim, Younghoon

    2016-08-01

    The objective of this study was to investigate the effect of 2 plant leaf extracts on fermentation mechanisms and health-promoting activities and their potential as a nutraceutical prebiotics ingredient for application in dairy products. The individual active phenolic compounds in the plant extract-supplemented milk and yogurts were also identified. Compared with control fermentation, the plant extracts significantly increased the growth and acidification rate of Streptococcus thermophilus and Lactobacillus delbrueckii ssp. bulgaricus. In particular, plant extract components, including monosaccharides, formic acid, and hydroxycinnamic acid, such as neo-chlorogenic, chlorogenic, and caffeic acid, together play a stimulatory role and cause this beneficial effect on the growth of yogurt culture bacteria through fermentation. In addition, supplementation with the plant extracts enhanced antioxidant activities with increased total phenolic contents, especially the highest antioxidant activity was observed in yogurt supplemented with Cudrania tricuspidata leaf extract. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  14. Revised description and classification of atypical isolates of Pasteurella multocida from bovine lungs based on genotypic characterization to include variants previously classified as biovar 2 of Pasteurella canis and Pasteurella avium

    DEFF Research Database (Denmark)

    Christensen, Henrik; Angen, Øystein; Olsen, John E.

    2004-01-01

    Strains deviating in key phenotypic characters, mainly isolated from cases of bovine pneumonia in five European countries, were genotyped in order to examine their genotypic relationship with Pasteurella multocida. Twenty-two strains of Pasteurella avium biovar 2, including variants in indole, xy...

  15. Theory of random sets

    CERN Document Server

    Molchanov, Ilya

    2017-01-01

    This monograph, now in a thoroughly revised second edition, offers the latest research on random sets. It has been extended to include substantial developments achieved since 2005, some of them motivated by applications of random sets to econometrics and finance. The present volume builds on the foundations laid by Matheron and others, including the vast advances in stochastic geometry, probability theory, set-valued analysis, and statistical inference. It shows the various interdisciplinary relationships of random set theory within other parts of mathematics, and at the same time fixes terminology and notation that often vary in the literature, establishing it as a natural part of modern probability theory and providing a platform for future development. It is completely self-contained, systematic and exhaustive, with the full proofs that are necessary to gain insight. Aimed at research level, Theory of Random Sets will be an invaluable reference for probabilists; mathematicians working in convex and integ...

  16. Characterization and Alteration of Wettability States of Alaskan Reserviors to Improve Oil Recovery Efficiency (including the within-scope expansion based on Cyclic Water Injection - a pulsed waterflood for Enhanced Oil Recovery)

    Energy Technology Data Exchange (ETDEWEB)

    Abhijit Dandekar; Shirish Patil; Santanu Khataniar

    2008-12-31

    , cyclic water injection tests using high as well as low salinity were also conducted on several representative ANS core samples. These results indicate that less pore volume of water is required to recover the same amount of oil as compared with continuous water injection. Additionally, in cyclic water injection, oil is produced even during the idle time of water injection. It is understood that the injected brine front spreads/smears through the pores and displaces oil out uniformly rather than viscous fingering. The overall benefits of this project include increased oil production from existing Alaskan reservoirs. This conclusion is based on the performed experiments and results obtained on low-salinity water injection (including ANS lake water), vis-a-vis slightly altering the wetting conditions. Similarly, encouraging cyclic water-injection test results indicate that this method can help achieve residual oil saturation earlier than continuous water injection. If proved in field, this would be of great use, as more oil can be recovered through cyclic water injection for the same amount of water injected.

  17. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

    Science.gov (United States)

    Nuss, Jonathan E; Kehn-Hall, Kylene; Benedict, Ashwini; Costantino, Julie; Ward, Michael; Peyser, Brian D; Retterer, Cary J; Tressler, Lyal E; Wanner, Laura M; McGovern, Hugh F; Zaidi, Anum; Anthony, Scott M; Kota, Krishna P; Bavari, Sina; Hakami, Ramin M

    2014-01-01

    Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV). Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have suggested case fatality rates of greater than thirty percent. To elucidate the roles that host proteins play during RVFV infection, proteomic analysis of RVFV virions was conducted using complementary analytical approaches, followed by functional validation studies of select identified host factors. Coupling the more traditional Gel LC/MS/MS approach (SDS PAGE followed by liquid chromatography tandem mass spectrometry) with an alternative technique that preserves protein complexes allowed the protein complement of these viral particles to be thoroughly examined. In addition to viral proteins present within the virions and virion-associated host proteins, multiple macromolecular complexes were identified. Bioinformatic analysis showed that host chaperones were among over-represented protein families associated with virions, and functional experiments using siRNA gene silencing and small molecule inhibitors identified several of these heat shock proteins, including heat shock protein 90 (HSP90), as important viral host factors. Further analysis indicated that HSP inhibition effects occur during the replication/transcription phase of the virus life cycle, leading to significant lowering of viral titers without compromising the functional capacity of released virions. Overall, these studies provide much needed further insight into interactions between RVFV and host cells, increasing our understanding of the infection process and suggesting novel strategies for anti-viral development. In particular, considering that several HSP90 inhibitors have been advancing through clinical trials for cancer treatment, these results also highlight the exciting potential of repurposing HSP90 inhibitors to treat RVF.

  18. Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.

    Directory of Open Access Journals (Sweden)

    Jonathan E Nuss

    Full Text Available Rift Valley fever is a potentially fatal disease of humans and domestic animals caused by Rift Valley fever virus (RVFV. Infection with RVFV in ruminants can cause near 100% abortion rates and recent outbreaks in naïve human populations have suggested case fatality rates of greater than thirty percent. To elucidate the roles that host proteins play during RVFV infection, proteomic analysis of RVFV virions was conducted using complementary analytical approaches, followed by functional validation studies of select identified host factors. Coupling the more traditional Gel LC/MS/MS approach (SDS PAGE followed by liquid chromatography tandem mass spectrometry with an alternative technique that preserves protein complexes allowed the protein complement of these viral particles to be thoroughly examined. In addition to viral proteins present within the virions and virion-associated host proteins, multiple macromolecular complexes were identified. Bioinformatic analysis showed that host chaperones were among over-represented protein families associated with virions, and functional experiments using siRNA gene silencing and small molecule inhibitors identified several of these heat shock proteins, including heat shock protein 90 (HSP90, as important viral host factors. Further analysis indicated that HSP inhibition effects occur during the replication/transcription phase of the virus life cycle, leading to significant lowering of viral titers without compromising the functional capacity of released virions. Overall, these studies provide much needed further insight into interactions between RVFV and host cells, increasing our understanding of the infection process and suggesting novel strategies for anti-viral development. In particular, considering that several HSP90 inhibitors have been advancing through clinical trials for cancer treatment, these results also highlight the exciting potential of repurposing HSP90 inhibitors to treat RVF.

  19. An advanced joint inversion system for CO2 storage modeling with large date sets for characterization and real-time monitoring-enhancing storage performance and reducing failure risks under uncertainties

    Energy Technology Data Exchange (ETDEWEB)

    Kitanidis, Peter [Stanford Univ., CA (United States)

    2016-04-30

    As large-scale, commercial storage projects become operational, the problem of utilizing information from diverse sources becomes more critically important. In this project, we developed, tested, and applied an advanced joint data inversion system for CO2 storage modeling with large data sets for use in site characterization and real-time monitoring. Emphasis was on the development of advanced and efficient computational algorithms for joint inversion of hydro-geophysical data, coupled with state-of-the-art forward process simulations. The developed system consists of (1) inversion tools using characterization data, such as 3D seismic survey (amplitude images), borehole log and core data, as well as hydraulic, tracer and thermal tests before CO2 injection, (2) joint inversion tools for updating the geologic model with the distribution of rock properties, thus reducing uncertainty, using hydro-geophysical monitoring data, and (3) highly efficient algorithms for directly solving the dense or sparse linear algebra systems derived from the joint inversion. The system combines methods from stochastic analysis, fast linear algebra, and high performance computing. The developed joint inversion tools have been tested through synthetic CO2 storage examples.

  20. A note on extreme sets

    Directory of Open Access Journals (Sweden)

    Radosław Cymer

    2017-10-01

    Full Text Available In decomposition theory, extreme sets have been studied extensively due to its connection to perfect matchings in a graph. In this paper, we first define extreme sets with respect to degree-matchings and next investigate some of their properties. In particular, we prove the generalized Decomposition Theorem and give a characterization for the set of all extreme vertices in a graph.

  1. Basic set theory

    CERN Document Server

    Levy, Azriel

    2002-01-01

    An advanced-level treatment of the basics of set theory, this text offers students a firm foundation, stopping just short of the areas employing model-theoretic methods. Geared toward upper-level undergraduate and graduate students, it consists of two parts: the first covers pure set theory, including the basic motions, order and well-foundedness, cardinal numbers, the ordinals, and the axiom of choice and some of it consequences; the second deals with applications and advanced topics such as point set topology, real spaces, Boolean algebras, and infinite combinatorics and large cardinals. An

  2. Set theory essentials

    CERN Document Server

    Milewski, Emil G

    2012-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Set Theory includes elementary logic, sets, relations, functions, denumerable and non-denumerable sets, cardinal numbers, Cantor's theorem, axiom of choice, and order relations.

  3. Initial data sets for the Schwarzschild spacetime

    International Nuclear Information System (INIS)

    Gomez-Lobo, Alfonso Garcia-Parrado; Kroon, Juan A. Valiente

    2007-01-01

    A characterization of initial data sets for the Schwarzschild spacetime is provided. This characterization is obtained by performing a 3+1 decomposition of a certain invariant characterization of the Schwarzschild spacetime given in terms of concomitants of the Weyl tensor. This procedure renders a set of necessary conditions--which can be written in terms of the electric and magnetic parts of the Weyl tensor and their concomitants--for an initial data set to be a Schwarzschild initial data set. Our approach also provides a formula for a static Killing initial data set candidate--a KID candidate. Sufficient conditions for an initial data set to be a Schwarzschild initial data set are obtained by supplementing the necessary conditions with the requirement that the initial data set possesses a stationary Killing initial data set of the form given by our KID candidate. Thus, we obtain an algorithmic procedure of checking whether a given initial data set is Schwarzschildean or not

  4. Set discrimination of quantum states

    International Nuclear Information System (INIS)

    Zhang Shengyu; Ying Mingsheng

    2002-01-01

    We introduce a notion of set discrimination, which is an interesting extension of quantum state discrimination. A state is secretly chosen from a number of quantum states, which are partitioned into some disjoint sets. A set discrimination is required to identify which set the given state belongs to. Several essential problems are addressed in this paper, including the condition of perfect set discrimination, unambiguous set discrimination, and in the latter case, the efficiency of the discrimination. This generalizes some important results on quantum state discrimination in the literature. A combination of state and set discrimination and the efficiency are also studied

  5. Data Sets from Major NCI Initiaves

    Science.gov (United States)

    The NCI Data Catalog includes links to data collections produced by major NCI initiatives and other widely used data sets, including animal models, human tumor cell lines, epidemiology data sets, genomics data sets from TCGA, TARGET, COSMIC, GSK, NCI60.

  6. Characterization of the CrbS/R Two-Component System in Pseudomonas fluorescens Reveals a New Set of Genes under Its Control and a DNA Motif Required for CrbR-Mediated Transcriptional Activation

    Directory of Open Access Journals (Sweden)

    Edgardo Sepulveda

    2017-11-01

    Full Text Available The CrbS/R system is a two-component signal transduction system that regulates acetate utilization in Vibrio cholerae, P. aeruginosa, and P. entomophila. CrbS is a hybrid histidine kinase that belongs to a recently identified family, in which the signaling domain is fused to an SLC5 solute symporter domain through aSTAC domain. Upon activation by CrbS, CrbR activates transcription of the acs gene, which encodes an acetyl-CoA synthase (ACS, and the actP gene, which encodes an acetate/solute symporter. In this work, we characterized the CrbS/R system in Pseudomonas fluorescens SBW25. Through the quantitative proteome analysis of different mutants, we were able to identify a new set of genes under its control, which play an important role during growth on acetate. These results led us to the identification of a conserved DNA motif in the putative promoter region of acetate-utilization genes in the Gammaproteobacteria that is essential for the CrbR-mediated transcriptional activation of genes under acetate-utilizing conditions. Finally, we took advantage of the existence of a second SLC5-containing two-component signal transduction system in P. fluorescens, CbrA/B, to demonstrate that the activation of the response regulator by the histidine kinase is not dependent on substrate transport through the SLC5 domain.

  7. Setting conservation priorities.

    Science.gov (United States)

    Wilson, Kerrie A; Carwardine, Josie; Possingham, Hugh P

    2009-04-01

    A generic framework for setting conservation priorities based on the principles of classic decision theory is provided. This framework encapsulates the key elements of any problem, including the objective, the constraints, and knowledge of the system. Within the context of this framework the broad array of approaches for setting conservation priorities are reviewed. While some approaches prioritize assets or locations for conservation investment, it is concluded here that prioritization is incomplete without consideration of the conservation actions required to conserve the assets at particular locations. The challenges associated with prioritizing investments through time in the face of threats (and also spatially and temporally heterogeneous costs) can be aided by proper problem definition. Using the authors' general framework for setting conservation priorities, multiple criteria can be rationally integrated and where, how, and when to invest conservation resources can be scheduled. Trade-offs are unavoidable in priority setting when there are multiple considerations, and budgets are almost always finite. The authors discuss how trade-offs, risks, uncertainty, feedbacks, and learning can be explicitly evaluated within their generic framework for setting conservation priorities. Finally, they suggest ways that current priority-setting approaches may be improved.

  8. Quantum mechanics over sets

    Science.gov (United States)

    Ellerman, David

    2014-03-01

    In models of QM over finite fields (e.g., Schumacher's ``modal quantum theory'' MQT), one finite field stands out, Z2, since Z2 vectors represent sets. QM (finite-dimensional) mathematics can be transported to sets resulting in quantum mechanics over sets or QM/sets. This gives a full probability calculus (unlike MQT with only zero-one modalities) that leads to a fulsome theory of QM/sets including ``logical'' models of the double-slit experiment, Bell's Theorem, QIT, and QC. In QC over Z2 (where gates are non-singular matrices as in MQT), a simple quantum algorithm (one gate plus one function evaluation) solves the Parity SAT problem (finding the parity of the sum of all values of an n-ary Boolean function). Classically, the Parity SAT problem requires 2n function evaluations in contrast to the one function evaluation required in the quantum algorithm. This is quantum speedup but with all the calculations over Z2 just like classical computing. This shows definitively that the source of quantum speedup is not in the greater power of computing over the complex numbers, and confirms the idea that the source is in superposition.

  9. On a type of generalized closed sets

    Directory of Open Access Journals (Sweden)

    Dhananjoy Mandal

    2012-01-01

    Full Text Available The purpose of this paper is to introduce and study a new class ofgeneralized closed sets in a topological space X, defined in terms of a grill G on X. Explicit characterization of such sets along with certain other properties of them are obtained. As applications, some characterizations of regular and normal spaces are achieved by use of the introduced class of sets.

  10. Models for setting ATM parameter values

    DEFF Research Database (Denmark)

    Blaabjerg, Søren; Gravey, A.; Romæuf, L.

    1996-01-01

    essential to set traffic characteristic values that are relevant to the considered cell stream, and that ensure that the amount of non-conforming traffic is small. Using a queueing model representation for the GCRA formalism, several methods are available for choosing the traffic characteristics. This paper......In ATM networks, a user should negotiate at connection set-up a traffic contract which includes traffic characteristics and requested QoS. The traffic characteristics currently considered are the Peak Cell Rate, the Sustainable Cell Rate, the Intrinsic Burst Tolerance and the Cell Delay Variation...... (CDV) tolerance(s). The values taken by these traffic parameters characterize the so-called ''Worst Case Traffic'' that is used by CAC procedures for accepting a new connection and allocating resources to it. Conformance to the negotiated traffic characteristics is defined, at the ingress User...

  11. Hesitant fuzzy sets theory

    CERN Document Server

    Xu, Zeshui

    2014-01-01

    This book provides the readers with a thorough and systematic introduction to hesitant fuzzy theory. It presents the most recent research results and advanced methods in the field. These includes: hesitant fuzzy aggregation techniques, hesitant fuzzy preference relations, hesitant fuzzy measures, hesitant fuzzy clustering algorithms and hesitant fuzzy multi-attribute decision making methods. Since its introduction by Torra and Narukawa in 2009, hesitant fuzzy sets have become more and more popular and have been used for a wide range of applications, from decision-making problems to cluster analysis, from medical diagnosis to personnel appraisal and information retrieval. This book offers a comprehensive report on the state-of-the-art in hesitant fuzzy sets theory and applications, aiming at becoming a reference guide for both researchers and practitioners in the area of fuzzy mathematics and other applied research fields (e.g. operations research, information science, management science and engineering) chara...

  12. Beyond 18F-FDG: Characterization of PET/CT and PET/MR Scanners for a Comprehensive Set of Positron Emitters of Growing Application--18F, 11C, 89Zr, 124I, 68Ga, and 90Y.

    Science.gov (United States)

    Soderlund, A Therese; Chaal, Jasper; Tjio, Gabriel; Totman, John J; Conti, Maurizio; Townsend, David W

    2015-08-01

    This study aimed to investigate image quality for a comprehensive set of isotopes ((18)F, (11)C, (89)Zr, (124)I, (68)Ga, and (90)Y) on 2 clinical scanners: a PET/CT scanner and a PET/MR scanner. Image quality and spatial resolution were tested according to NU 2-2007 of the National Electrical Manufacturers Association. An image-quality phantom was used to measure contrast recovery, residual bias in a cold area, and background variability. Reconstruction methods available on the 2 scanners were compared, including point-spread-function correction for both scanners and time of flight for the PET/CT scanner. Spatial resolution was measured using point sources and filtered backprojection reconstruction. With the exception of (90)Y, small differences were seen in the hot-sphere contrast recovery of the different isotopes. Cold-sphere contrast recovery was similar across isotopes for all reconstructions, with an improvement seen with time of flight on the PET/CT scanner. The lower-statistic (90)Y scans yielded substantially lower contrast recovery than the other isotopes. When isotopes were compared, there was no difference in measured spatial resolution except for PET/MR axial spatial resolution, which was significantly higher for (124)I and (68)Ga. Overall, both scanners produced good images with (18)F, (11)C, (89)Zr, (124)I, (68)Ga, and (90)Y. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

  13. UpSet: Visualization of Intersecting Sets

    Science.gov (United States)

    Lex, Alexander; Gehlenborg, Nils; Strobelt, Hendrik; Vuillemot, Romain; Pfister, Hanspeter

    2016-01-01

    Understanding relationships between sets is an important analysis task that has received widespread attention in the visualization community. The major challenge in this context is the combinatorial explosion of the number of set intersections if the number of sets exceeds a trivial threshold. In this paper we introduce UpSet, a novel visualization technique for the quantitative analysis of sets, their intersections, and aggregates of intersections. UpSet is focused on creating task-driven aggregates, communicating the size and properties of aggregates and intersections, and a duality between the visualization of the elements in a dataset and their set membership. UpSet visualizes set intersections in a matrix layout and introduces aggregates based on groupings and queries. The matrix layout enables the effective representation of associated data, such as the number of elements in the aggregates and intersections, as well as additional summary statistics derived from subset or element attributes. Sorting according to various measures enables a task-driven analysis of relevant intersections and aggregates. The elements represented in the sets and their associated attributes are visualized in a separate view. Queries based on containment in specific intersections, aggregates or driven by attribute filters are propagated between both views. We also introduce several advanced visual encodings and interaction methods to overcome the problems of varying scales and to address scalability. UpSet is web-based and open source. We demonstrate its general utility in multiple use cases from various domains. PMID:26356912

  14. (including travel dates) Proposed itinerary

    Indian Academy of Sciences (India)

    Ashok

    31 July to 22 August 2012 (including travel dates). Proposed itinerary: Arrival in Bangalore on 1 August. 1-5 August: Bangalore, Karnataka. Suggested institutions: Indian Institute of Science, Bangalore. St Johns Medical College & Hospital, Bangalore. Jawaharlal Nehru Centre, Bangalore. 6-8 August: Chennai, TN.

  15. Fuzzy sets, rough sets, multisets and clustering

    CERN Document Server

    Dahlbom, Anders; Narukawa, Yasuo

    2017-01-01

    This book is dedicated to Prof. Sadaaki Miyamoto and presents cutting-edge papers in some of the areas in which he contributed. Bringing together contributions by leading researchers in the field, it concretely addresses clustering, multisets, rough sets and fuzzy sets, as well as their applications in areas such as decision-making. The book is divided in four parts, the first of which focuses on clustering and classification. The second part puts the spotlight on multisets, bags, fuzzy bags and other fuzzy extensions, while the third deals with rough sets. Rounding out the coverage, the last part explores fuzzy sets and decision-making.

  16. Advances in type-2 fuzzy sets and systems theory and applications

    CERN Document Server

    Mendel, Jerry; Tahayori, Hooman

    2013-01-01

    This book explores recent developments in the theoretical foundations and novel applications of general and interval type-2 fuzzy sets and systems, including: algebraic properties of type-2 fuzzy sets, geometric-based definition of type-2 fuzzy set operators, generalizations of the continuous KM algorithm, adaptiveness and novelty of interval type-2 fuzzy logic controllers, relations between conceptual spaces and type-2 fuzzy sets, type-2 fuzzy logic systems versus perceptual computers; modeling human perception of real world concepts with type-2 fuzzy sets, different methods for generating membership functions of interval and general type-2 fuzzy sets, and applications of interval type-2 fuzzy sets to control, machine tooling, image processing and diet.  The applications demonstrate the appropriateness of using type-2 fuzzy sets and systems in real world problems that are characterized by different degrees of uncertainty.

  17. Theory including future not excluded

    DEFF Research Database (Denmark)

    Nagao, K.; Nielsen, H.B.

    2013-01-01

    We study a complex action theory (CAT) whose path runs over not only past but also future. We show that, if we regard a matrix element defined in terms of the future state at time T and the past state at time TA as an expectation value in the CAT, then we are allowed to have the Heisenberg equation......, Ehrenfest's theorem, and the conserved probability current density. In addition,we showthat the expectation value at the present time t of a future-included theory for large T - t and large t - T corresponds to that of a future-not-included theory with a proper inner product for large t - T. Hence, the CAT...

  18. Setting oral health goals that include oral health-related quality of life measures: a study carried out among adolescents in Thailand Incorporação da qualidade de vida relacionada à saúde bucal em metas de saúde bucal: estudo conduzido em adolescentes tailandeses

    Directory of Open Access Journals (Sweden)

    Sudaduang Krisdapong

    2012-10-01

    Full Text Available The aim of this study was to assess the association between oral diseases and condition-specific oral health-related quality of life (CS-OHRQoL as a basis for proposing OHRQoL-based goals for the population of 15-year-olds in Thailand. Oral examinations and OHRQoL interviews were conducted with 871 15-year-olds as part of the Sixth Thailand National Oral Health Survey. The severity of oral impacts was categorized using "intensity". Associations between oral diseases and CS-OHRQoL were analyzed using chi-square and logistic regression. Thirty-nine percent of 15-year-olds experienced moderate/higher levels oral impacts on quality of life. Compared to those individuals with no tooth decay, adolescents with one or four or more decaying teeth were three and seven times more likely to experience moderate/higher impacts, respectively. Adolescents with extensive gingivitis in 3 or more mouth sextants were twice as likely to experience moderate/higher CS-impacts. Based on these findings, it is proposed that goals should focus on untreated decaying teeth and extensive gingivitis. Oral health goals for 15-year-olds should include specific OHRQoL measures.O objetivo deste estudo foi avaliar a associação entre doença bucal e a condição específica de qualidade de vida associada à saúde bucal (CS-OHRQoL, como base para propor OHRQoL metas para adolescentes tailandeses. Exame clínico bucal e entrevista foram realizados em 871 adolescentes na faixa etária de 15 anos, como parte da 6ª Pesquisa Nacional Tailandesa de Saúde Bucal. A severidade do impacto bucal foi categorizada usando-se a "intensidade". A associação entre doença bucal e CS-OHRQoL foi investigada usando-se o teste qui-quadrado e regressão lógica. Trinta e nove por cento da amostra reportaram impactos bucais de grau moderado/elevado. A probabilidade de reportar um impacto bucal de grau moderado/elevado dos adolescentes com um dente cariado e aqueles com 4 ou mais foi 3 e 7 vezes

  19. Device including a contact detector

    DEFF Research Database (Denmark)

    2011-01-01

    arms (12) may extend from the supporting body in co-planar relationship with the first surface. The plurality of cantilever arms (12) may extend substantially parallel to each other and each of the plurality of cantilever arms (12) may include an electrical conductive tip for contacting the area......The present invention relates to a probe for determining an electrical property of an area of a surface of a test sample, the probe is intended to be in a specific orientation relative to the test sample. The probe may comprise a supporting body defining a first surface. A plurality of cantilever...... of the test sample by movement of the probe relative to the surface of the test sample into the specific orientation.; The probe may further comprise a contact detector (14) extending from the supporting body arranged so as to contact the surface of the test sample prior to any one of the plurality...

  20. Neoclassical transport including collisional nonlinearity.

    Science.gov (United States)

    Candy, J; Belli, E A

    2011-06-10

    In the standard δf theory of neoclassical transport, the zeroth-order (Maxwellian) solution is obtained analytically via the solution of a nonlinear equation. The first-order correction δf is subsequently computed as the solution of a linear, inhomogeneous equation that includes the linearized Fokker-Planck collision operator. This equation admits analytic solutions only in extreme asymptotic limits (banana, plateau, Pfirsch-Schlüter), and so must be solved numerically for realistic plasma parameters. Recently, numerical codes have appeared which attempt to compute the total distribution f more accurately than in the standard ordering by retaining some nonlinear terms related to finite-orbit width, while simultaneously reusing some form of the linearized collision operator. In this work we show that higher-order corrections to the distribution function may be unphysical if collisional nonlinearities are ignored.

  1. Functional Multiple-Set Canonical Correlation Analysis

    Science.gov (United States)

    Hwang, Heungsun; Jung, Kwanghee; Takane, Yoshio; Woodward, Todd S.

    2012-01-01

    We propose functional multiple-set canonical correlation analysis for exploring associations among multiple sets of functions. The proposed method includes functional canonical correlation analysis as a special case when only two sets of functions are considered. As in classical multiple-set canonical correlation analysis, computationally, the…

  2. SETS reference manual

    International Nuclear Information System (INIS)

    Worrell, R.B.

    1985-05-01

    The Set Equation Transformation System (SETS) is used to achieve the symbolic manipulation of Boolean equations. Symbolic manipulation involves changing equations from their original forms into more useful forms - particularly by applying Boolean identities. The SETS program is an interpreter which reads, interprets, and executes SETS user programs. The user writes a SETS user program specifying the processing to be achieved and submits it, along with the required data, for execution by SETS. Because of the general nature of SETS, i.e., the capability to manipulate Boolean equations regardless of their origin, the program has been used for many different kinds of analysis

  3. On θ-generalized closed sets

    Directory of Open Access Journals (Sweden)

    Julian Dontchev

    1999-01-01

    θ-generalized Λ-sets and R0-, T1/2- and T1-spaces are characterized. The relations with other notions directly or indirectly connected with generalized closed sets are investigated. The notion of TGO-connectedness is introduced.

  4. Introduction to Fuzzy Set Theory

    Science.gov (United States)

    Kosko, Bart

    1990-01-01

    An introduction to fuzzy set theory is described. Topics covered include: neural networks and fuzzy systems; the dynamical systems approach to machine intelligence; intelligent behavior as adaptive model-free estimation; fuzziness versus probability; fuzzy sets; the entropy-subsethood theorem; adaptive fuzzy systems for backing up a truck-and-trailer; product-space clustering with differential competitive learning; and adaptive fuzzy system for target tracking.

  5. Systemic consultation and goal setting

    OpenAIRE

    Carr, Alan

    1993-01-01

    Over two decades of empirical research conducted within a positivist framework has shown that goal setting is a particularly useful method for influencing task performance in occupational and industrial contexts. The conditions under which goal setting is maximally effective are now clearly established. These include situations where there is a high level of acceptance and commitment, where goals are specific and challenging, where the task is relatively simple rather than ...

  6. Sets in Coq, Coq in Sets

    Directory of Open Access Journals (Sweden)

    Bruno Barras

    2010-01-01

    Full Text Available This work is about formalizing models of various type theories of the Calculus of Constructions family. Here we focus on set theoretical models. The long-term goal is to build a formal set theoretical model of the Calculus of Inductive Constructions, so we can be sure that Coq is consistent with the language used by most mathematicians.One aspect of this work is to axiomatize several set theories: ZF possibly with inaccessible cardinals, and HF, the theory of hereditarily finite sets. On top of these theories we have developped a piece of the usual set theoretical construction of functions, ordinals and fixpoint theory. We then proved sound several models of the Calculus of Constructions, its extension with an infinite hierarchy of universes, and its extension with the inductive type of natural numbers where recursion follows the type-based termination approach.The other aspect is to try and discharge (most of these assumptions. The goal here is rather to compare the theoretical strengths of all these formalisms. As already noticed by Werner, the replacement axiom of ZF in its general form seems to require a type-theoretical axiom of choice (TTAC.

  7. Setting Global Research Priorities for Developmental Disabilities, Including Intellectual Disabilities and Autism

    Science.gov (United States)

    Tomlinson, M.; Yasamy, M. T.; Emerson, E.; Officer, A.; Richler, D.; Saxena, S.

    2014-01-01

    Objectives: The prevalence of intellectual disabilities (ID) has been estimated at 10.4/1000 worldwide with higher rates among children and adolescents in lower income countries. The objective of this paper is to address research priorities for development disabilities, notably ID and autism, at the global level and to propose the more rational…

  8. Priority setting in practice: participants opinions on vertical and horizontal priority setting for reallocation.

    Science.gov (United States)

    Waldau, Susanne; Lindholm, Lars; Wiechel, Anna Helena

    2010-08-01

    In the Västerbotten County Council in Sweden a priority setting process was undertaken to reallocate existing resources for funding of new methods and activities. Resources were created by limiting low priority services. A procedure for priority setting was constructed and fully tested by engaging the entire organisation. The procedure included priority setting within and between departments and political decision making. Participants' views and experiences were collected as a basis for future improvement of the process. Results indicate that participants appreciated the overall approach and methodology and wished to engage in their improvement. Among the improvement proposals is prolongation of the process in order to improve the knowledge base quality. The procedure for identification of new items for funding also needs to be revised. The priority setting process was considered an overall success because it fulfilled its political goals. Factors considered crucial for success are a wish among managers for an economic strategy that addresses existing internal resource allocation; process management characterized by goal orientation and clear leadership; an elaborate communications strategy integrated early in the process and its management; political unity in support of the procedure, and a strong political commitment throughout the process. Generalizability has already been demonstrated by several health care organisations that performed processes founded on this working model. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  9. Invariant sets for Windows

    CERN Document Server

    Morozov, Albert D; Dragunov, Timothy N; Malysheva, Olga V

    1999-01-01

    This book deals with the visualization and exploration of invariant sets (fractals, strange attractors, resonance structures, patterns etc.) for various kinds of nonlinear dynamical systems. The authors have created a special Windows 95 application called WInSet, which allows one to visualize the invariant sets. A WInSet installation disk is enclosed with the book.The book consists of two parts. Part I contains a description of WInSet and a list of the built-in invariant sets which can be plotted using the program. This part is intended for a wide audience with interests ranging from dynamical

  10. Value Set Authority Center

    Data.gov (United States)

    U.S. Department of Health & Human Services — The VSAC provides downloadable access to all official versions of vocabulary value sets contained in the 2014 Clinical Quality Measures (CQMs). Each value set...

  11. Settings for Suicide Prevention

    Science.gov (United States)

    ... Suicide Populations Racial/Ethnic Groups Older Adults Adolescents LGBT Military/Veterans Men Effective Prevention Comprehensive Approach Identify ... Based Prevention Settings American Indian/Alaska Native Settings Schools Colleges and Universities Primary Care Emergency Departments Behavioral ...

  12. Practical materials characterization

    CERN Document Server

    2014-01-01

    Presents cross-comparison between materials characterization techniquesIncludes clear specifications of strengths and limitations of each technique for specific materials characterization problemFocuses on applications and clear data interpretation without extensive mathematics

  13. Alternate superior Julia sets

    International Nuclear Information System (INIS)

    Yadav, Anju; Rani, Mamta

    2015-01-01

    Alternate Julia sets have been studied in Picard iterative procedures. The purpose of this paper is to study the quadratic and cubic maps using superior iterates to obtain Julia sets with different alternate structures. Analytically, graphically and computationally it has been shown that alternate superior Julia sets can be connected, disconnected and totally disconnected, and also fattier than the corresponding alternate Julia sets. A few examples have been studied by applying different type of alternate structures

  14. Solid-state nuclear magnetic resonance (NMR) spectroscopy of human immunodeficiency virus gp41 protein that includes the fusion peptide: NMR detection of recombinant Fgp41 in inclusion bodies in whole bacterial cells and structural characterization of purified and membrane-associated Fgp41.

    Science.gov (United States)

    Vogel, Erica P; Curtis-Fisk, Jaime; Young, Kaitlin M; Weliky, David P

    2011-11-22

    Human immunodeficiency virus (HIV) infection of a host cell begins with fusion of the HIV and host cell membranes and is mediated by the gp41 protein, a single-pass integral membrane protein of HIV. The 175 N-terminal residues make up the ectodomain that lies outside the virus. This work describes the production and characterization of an ectodomain construct containing the 154 N-terminal gp41 residues, including the fusion peptide (FP) that binds to target cell membranes. The Fgp41 sequence was derived from one of the African clade A strains of HIV-1 that have been less studied than European/North American clade B strains. Fgp41 expression at a level of ~100 mg/L of culture was evidenced by an approach that included amino acid type (13)CO and (15)N labeling of recombinant protein and solid-state NMR (SSNMR) spectroscopy of lyophilized whole cells. The approach did not require any protein solubilization or purification and may be a general approach for detection of recombinant protein. The purified Fgp41 yield was ~5 mg/L of culture. SSNMR spectra of membrane-associated Fgp41 showed high helicity for the residues C-terminal of the FP. This was consistent with a "six-helix bundle" (SHB) structure that is the final gp41 state during membrane fusion. This observation and negligible Fgp41-induced vesicle fusion supported a function for SHB gp41 of membrane stabilization and fusion arrest. SSNMR spectra of residues in the membrane-associated FP provided evidence of a mixture of molecular populations with either helical or β-sheet FP conformation. These and earlier SSNMR data strongly support the existence of these populations in the SHB state of membrane-associated gp41. © 2011 American Chemical Society

  15. A Data Set of Portuguese Traditional Recipes Based on Published Cookery Books

    Directory of Open Access Journals (Sweden)

    Alexandra Soveral Dias

    2018-03-01

    Full Text Available This paper presents a data set resulting from the abstraction of books of traditional recipes for Portuguese cuisine. Only starters, main courses, side dishes, and soups were considered. Desserts, cakes, sweets, puddings, and pastries were not included. Recipes were characterized by the province and ingredients regardless of quantities or preparation. An exploratory characterization of recipes and ingredients is presented. Results show that Portuguese traditional recipes organize differently among the eleven provinces considered, setting up the basis for more detailed analyses of the 1382 recipes and 421 ingredients inventoried.

  16. Sets, Planets, and Comets

    Science.gov (United States)

    Baker, Mark; Beltran, Jane; Buell, Jason; Conrey, Brian; Davis, Tom; Donaldson, Brianna; Detorre-Ozeki, Jeanne; Dibble, Leila; Freeman, Tom; Hammie, Robert; Montgomery, Julie; Pickford, Avery; Wong, Justine

    2013-01-01

    Sets in the game "Set" are lines in a certain four-dimensional space. Here we introduce planes into the game, leading to interesting mathematical questions, some of which we solve, and to a wonderful variation on the game "Set," in which every tableau of nine cards must contain at least one configuration for a player to pick up.

  17. Axiomatic set theory

    CERN Document Server

    Suppes, Patrick

    1972-01-01

    This clear and well-developed approach to axiomatic set theory is geared toward upper-level undergraduates and graduate students. It examines the basic paradoxes and history of set theory and advanced topics such as relations and functions, equipollence, finite sets and cardinal numbers, rational and real numbers, and other subjects. 1960 edition.

  18. Paired fuzzy sets

    DEFF Research Database (Denmark)

    Rodríguez, J. Tinguaro; Franco de los Ríos, Camilo; Gómez, Daniel

    2015-01-01

    In this paper we want to stress the relevance of paired fuzzy sets, as already proposed in previous works of the authors, as a family of fuzzy sets that offers a unifying view for different models based upon the opposition of two fuzzy sets, simply allowing the existence of different types...

  19. Elements of set theory

    CERN Document Server

    Enderton, Herbert B

    1977-01-01

    This is an introductory undergraduate textbook in set theory. In mathematics these days, essentially everything is a set. Some knowledge of set theory is necessary part of the background everyone needs for further study of mathematics. It is also possible to study set theory for its own interest--it is a subject with intruiging results anout simple objects. This book starts with material that nobody can do without. There is no end to what can be learned of set theory, but here is a beginning.

  20. Social Set Analysis

    DEFF Research Database (Denmark)

    Vatrapu, Ravi; Mukkamala, Raghava Rao; Hussain, Abid

    2016-01-01

    , conceptual and formal models of social data, and an analytical framework for combining big social data sets with organizational and societal data sets. Three empirical studies of big social data are presented to illustrate and demonstrate social set analysis in terms of fuzzy set-theoretical sentiment...... automata and agent-based modeling). However, when it comes to organizational and societal units of analysis, there exists no approach to conceptualize, model, analyze, explain, and predict social media interactions as individuals' associations with ideas, values, identities, and so on. To address...... analysis, crisp set-theoretical interaction analysis, and event-studies-oriented set-theoretical visualizations. Implications for big data analytics, current limitations of the set-theoretical approach, and future directions are outlined....

  1. (L) Sets and almost (L) seys in Banach lattices | Aqzzouz ...

    African Journals Online (AJOL)

    We characterize (L) sets and almost (L) sets in Banach lattices. Also, we look at Banach lattices in which these two classes of sets coincide. Keywords: (L) sets, Dunford-Pettis operator, almost Dunford-Pettis operator. Quaestiones Mathematicae 36(2013), 107-118 ...

  2. Setting the scene

    International Nuclear Information System (INIS)

    Curran, S.

    1977-01-01

    The reasons for the special meeting on the breeder reactor are outlined with some reference to the special Scottish interest in the topic. Approximately 30% of the electrical energy generated in Scotland is nuclear and the special developments at Dounreay make policy decisions on the future of the commercial breeder reactor urgent. The participants review the major questions arising in arriving at such decisions. In effect an attempt is made to respond to the wish of the Secretary of State for Energy to have informed debate. To set the scene the importance of energy availability as regards to the strength of the national economy is stressed and the reasons for an increasing energy demand put forward. Examination of alternative sources of energy shows that none is definitely capable of filling the foreseen energy gap. This implies an integrated thermal/breeder reactor programme as the way to close the anticipated gap. The problems of disposal of radioactive waste and the safeguards in the handling of plutonium are outlined. Longer-term benefits, including the consumption of plutonium and naturally occurring radioactive materials, are examined. (author)

  3. On Some Nonclassical Algebraic Properties of Interval-Valued Fuzzy Soft Sets

    Directory of Open Access Journals (Sweden)

    Xiaoyan Liu

    2014-01-01

    Full Text Available Interval-valued fuzzy soft sets realize a hybrid soft computing model in a general framework. Both Molodtsov’s soft sets and interval-valued fuzzy sets can be seen as special cases of interval-valued fuzzy soft sets. In this study, we first compare four different types of interval-valued fuzzy soft subsets and reveal the relations among them. Then we concentrate on investigating some nonclassical algebraic properties of interval-valued fuzzy soft sets under the soft product operations. We show that some fundamental algebraic properties including the commutative and associative laws do not hold in the conventional sense, but hold in weaker forms characterized in terms of the relation =L. We obtain a number of algebraic inequalities of interval-valued fuzzy soft sets characterized by interval-valued fuzzy soft inclusions. We also establish the weak idempotent law and the weak absorptive law of interval-valued fuzzy soft sets using interval-valued fuzzy soft J-equal relations. It is revealed that the soft product operations ∧ and ∨ of interval-valued fuzzy soft sets do not always have similar algebraic properties. Moreover, we find that only distributive inequalities described by the interval-valued fuzzy soft L-inclusions hold for interval-valued fuzzy soft sets.

  4. On some nonclassical algebraic properties of interval-valued fuzzy soft sets.

    Science.gov (United States)

    Liu, Xiaoyan; Feng, Feng; Zhang, Hui

    2014-01-01

    Interval-valued fuzzy soft sets realize a hybrid soft computing model in a general framework. Both Molodtsov's soft sets and interval-valued fuzzy sets can be seen as special cases of interval-valued fuzzy soft sets. In this study, we first compare four different types of interval-valued fuzzy soft subsets and reveal the relations among them. Then we concentrate on investigating some nonclassical algebraic properties of interval-valued fuzzy soft sets under the soft product operations. We show that some fundamental algebraic properties including the commutative and associative laws do not hold in the conventional sense, but hold in weaker forms characterized in terms of the relation = L . We obtain a number of algebraic inequalities of interval-valued fuzzy soft sets characterized by interval-valued fuzzy soft inclusions. We also establish the weak idempotent law and the weak absorptive law of interval-valued fuzzy soft sets using interval-valued fuzzy soft J-equal relations. It is revealed that the soft product operations ∧ and ∨ of interval-valued fuzzy soft sets do not always have similar algebraic properties. Moreover, we find that only distributive inequalities described by the interval-valued fuzzy soft L-inclusions hold for interval-valued fuzzy soft sets.

  5. On Some Nonclassical Algebraic Properties of Interval-Valued Fuzzy Soft Sets

    Science.gov (United States)

    2014-01-01

    Interval-valued fuzzy soft sets realize a hybrid soft computing model in a general framework. Both Molodtsov's soft sets and interval-valued fuzzy sets can be seen as special cases of interval-valued fuzzy soft sets. In this study, we first compare four different types of interval-valued fuzzy soft subsets and reveal the relations among them. Then we concentrate on investigating some nonclassical algebraic properties of interval-valued fuzzy soft sets under the soft product operations. We show that some fundamental algebraic properties including the commutative and associative laws do not hold in the conventional sense, but hold in weaker forms characterized in terms of the relation =L. We obtain a number of algebraic inequalities of interval-valued fuzzy soft sets characterized by interval-valued fuzzy soft inclusions. We also establish the weak idempotent law and the weak absorptive law of interval-valued fuzzy soft sets using interval-valued fuzzy soft J-equal relations. It is revealed that the soft product operations ∧ and ∨ of interval-valued fuzzy soft sets do not always have similar algebraic properties. Moreover, we find that only distributive inequalities described by the interval-valued fuzzy soft L-inclusions hold for interval-valued fuzzy soft sets. PMID:25143964

  6. Aerosol simulation including chemical and nuclear reactions

    International Nuclear Information System (INIS)

    Marwil, E.S.; Lemmon, E.C.

    1985-01-01

    The numerical simulation of aerosol transport, including the effects of chemical and nuclear reactions presents a challenging dynamic accounting problem. Particles of different sizes agglomerate and settle out due to various mechanisms, such as diffusion, diffusiophoresis, thermophoresis, gravitational settling, turbulent acceleration, and centrifugal acceleration. Particles also change size, due to the condensation and evaporation of materials on the particle. Heterogeneous chemical reactions occur at the interface between a particle and the suspending medium, or a surface and the gas in the aerosol. Homogeneous chemical reactions occur within the aersol suspending medium, within a particle, and on a surface. These reactions may include a phase change. Nuclear reactions occur in all locations. These spontaneous transmutations from one element form to another occur at greatly varying rates and may result in phase or chemical changes which complicate the accounting process. This paper presents an approach for inclusion of these effects on the transport of aerosols. The accounting system is very complex and results in a large set of stiff ordinary differential equations (ODEs). The techniques for numerical solution of these ODEs require special attention to achieve their solution in an efficient and affordable manner. 4 refs

  7. Development and characterization of a new set of genomic microsatellite markers in rice bean (Vigna umbellata (Thunb.) Ohwi and Ohashi) and their utilization in genetic diversity analysis of collections from North East India.

    Science.gov (United States)

    Iangrai, Banshanlang; Pattanayak, Arunava; Khongwir, D Evanoreen Ann; Pale, Gratify; Gatphoh, Emica Mary; Das, Alpana; Chrungoo, Nikhil Kumar

    2017-01-01

    Rice bean [Vigna umbellate (Thumb.) Ohwi and Ohashi] is an underutilized crop believed to be domesticated in the Myanmar-Thailand region of Asia. In India, rice bean is mainly cultivated in the North-Eastern Hills, which is a hotspot for biological diversity. A 5' anchored PCR was used to develop microsatellite markers in rice bean. Twenty-eight specific primer pairs were designed and employed to characterize sixty five ricebean accessions collected from North East India. A total of 179 alleles were amplified with an average of 6.393 alleles per locus. The gene diversity was high (mean 0.534) in the accessions collected from Darjeeling, Nagaland and Manipur, which are bordering areas with East Nepal and Myanmar, respectively. Exceptionally high outcrossing rate was observed in the entire population. Population structure analysis identified three distinct clusters in which accessions collected from areas bordering Myanmar and East Nepal grouped separately. Using a combination of STRUCTURE and Principal Coordinate Analysis, relative affinity of the intermediate accessions could be established. However, differences in allelic counts among populations were non-significant. The results showed that there is a high level of genetic diversity within the accessions, with high outcrossing rate.

  8. Haar meager sets revisited

    Czech Academy of Sciences Publication Activity Database

    Doležal, Martin; Rmoutil, M.; Vejnar, B.; Vlasák, V.

    2016-01-01

    Roč. 440, č. 2 (2016), s. 922-939 ISSN 0022-247X Institutional support: RVO:67985840 Keywords : Haar meager set * Haar null set * Polish group Subject RIV: BA - General Mathematics Impact factor: 1.064, year: 2016 http://www.sciencedirect.com/science/article/pii/S0022247X1600305X

  9. Setting goals in psychotherapy

    DEFF Research Database (Denmark)

    Emiliussen, Jakob; Wagoner, Brady

    2013-01-01

    The present study is concerned with the ethical dilemmas of setting goals in therapy. The main questions that it aims to answer are: who is to set the goals for therapy and who is to decide when they have been reached? The study is based on four semi-­‐structured, phenomenological interviews...

  10. Pseudo-set framing.

    Science.gov (United States)

    Barasz, Kate; John, Leslie K; Keenan, Elizabeth A; Norton, Michael I

    2017-10-01

    Pseudo-set framing-arbitrarily grouping items or tasks together as part of an apparent "set"-motivates people to reach perceived completion points. Pseudo-set framing changes gambling choices (Study 1), effort (Studies 2 and 3), giving behavior (Field Data and Study 4), and purchase decisions (Study 5). These effects persist in the absence of any reward, when a cost must be incurred, and after participants are explicitly informed of the arbitrariness of the set. Drawing on Gestalt psychology, we develop a conceptual account that predicts what will-and will not-act as a pseudo-set, and defines the psychological process through which these pseudo-sets affect behavior: over and above typical reference points, pseudo-set framing alters perceptions of (in)completeness, making intermediate progress seem less complete. In turn, these feelings of incompleteness motivate people to persist until the pseudo-set has been fulfilled. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  11. Descriptive set theory

    CERN Document Server

    Moschovakis, YN

    1987-01-01

    Now available in paperback, this monograph is a self-contained exposition of the main results and methods of descriptive set theory. It develops all the necessary background material from logic and recursion theory, and treats both classical descriptive set theory and the effective theory developed by logicians.

  12. Possibility Fuzzy Soft Set

    Directory of Open Access Journals (Sweden)

    Shawkat Alkhazaleh

    2011-01-01

    Full Text Available We introduce the concept of possibility fuzzy soft set and its operation and study some of its properties. We give applications of this theory in solving a decision-making problem. We also introduce a similarity measure of two possibility fuzzy soft sets and discuss their application in a medical diagnosis problem.

  13. Archaeological predictive model set.

    Science.gov (United States)

    2015-03-01

    This report is the documentation for Task 7 of the Statewide Archaeological Predictive Model Set. The goal of this project is to : develop a set of statewide predictive models to assist the planning of transportation projects. PennDOT is developing t...

  14. Large Data Set Mining

    NARCIS (Netherlands)

    Leemans, I.B.; Broomhall, Susan

    2017-01-01

    Digital emotion research has yet to make history. Until now large data set mining has not been a very active field of research in early modern emotion studies. This is indeed surprising since first, the early modern field has such rich, copyright-free, digitized data sets and second, emotion studies

  15. "Ready, Set, FLOW!"

    Science.gov (United States)

    Stroud, Wesley

    2018-01-01

    All educators want their classrooms to be inviting areas that support investigations. However, a common mistake is to fill learning spaces with items or objects that are set up by the teacher or are simply "for show." This type of setting, although it may create a comfortable space for students, fails to stimulate investigations and…

  16. Economic communication model set

    Science.gov (United States)

    Zvereva, Olga M.; Berg, Dmitry B.

    2017-06-01

    This paper details findings from the research work targeted at economic communications investigation with agent-based models usage. The agent-based model set was engineered to simulate economic communications. Money in the form of internal and external currencies was introduced into the models to support exchanges in communications. Every model, being based on the general concept, has its own peculiarities in algorithm and input data set since it was engineered to solve the specific problem. Several and different origin data sets were used in experiments: theoretic sets were estimated on the basis of static Leontief's equilibrium equation and the real set was constructed on the basis of statistical data. While simulation experiments, communication process was observed in dynamics, and system macroparameters were estimated. This research approved that combination of an agent-based and mathematical model can cause a synergetic effect.

  17. Au-As (lead) vein mineralizations of the Cevennes and Chataigneraie regions (French Massif Central). Isotopic characterization (Pb). Mineralizing role of granites in the setting up of these mineralizations

    International Nuclear Information System (INIS)

    Havard, M.L.

    1997-06-01

    This work has been carried out in the Frame of the national program 'Geofrance 3D' jointly organized by the French office for geologic and mining researches (BRGM), and the CNRS-INSU/DSPT3. Its aim is the study of the formation of gold-bearing mineralizations of the Variscan chain in the Cevennes and Chataigneraie regions (French Massif Central). In the Cevennes region, the gold-bearing veins are linked with the intrusion of the late-tectonic granodioritic plutons. The aim of this study is to determine the chronology of the mineralizing episodes and to analyze the relationship between the metal concentrates and the setting up of the granites. In the Chataigneraie region, the granites are intrusive in ortho- and para-gneiss series. The hydrothermal activity associated with the contact metamorphism should be responsible for the deposition of gold-bearing wolfram mineralization. The geochemistry of lead isotopes is used to determine the origin of metals in the sulfide mineralizations. The scanning electron microscopy (SEM) is used for the visualization of the microstructure heterogeneities of the minerals and for the quantitative chemical analysis of their successive para-geneses. The comparison between the results obtained in both regions allows to make a difference between their relative degree of erosion and their gold potentialities. (J.S.)

  18. Causal Set Generator and Action Computer

    OpenAIRE

    Cunningham, William; Krioukov, Dmitri

    2017-01-01

    The causal set approach to quantum gravity has gained traction over the past three decades, but numerical experiments involving causal sets have been limited to relatively small scales. The software suite presented here provides a new framework for the generation and study of causal sets. Its efficiency surpasses previous implementations by several orders of magnitude. We highlight several important features of the code, including the compact data structures, the $O(N^2)$ causal set generatio...

  19. A new MCNP trademark test set

    International Nuclear Information System (INIS)

    Brockhoff, R.C.; Hendricks, J.S.

    1994-09-01

    The MCNP test set is used to test the MCNP code after installation on various computer platforms. For MCNP4 and MCNP4A this test set included 25 test problems designed to test as many features of the MCNP code as possible. A new and better test set has been devised to increase coverage of the code from 85% to 97% with 28 problems. The new test set is as fast as and shorter than the MCNP4A test set. The authors describe the methodology for devising the new test set, the features that were not covered in the MCNP4A test set, and the changes in the MCNP4A test set that have been made for MCNP4B and its developmental versions. Finally, new bugs uncovered by the new test set and a compilation of all known MCNP4A bugs are presented

  20. Towards a Characterization of Rational Expectations

    OpenAIRE

    Itai Arieli

    2008-01-01

    R. J. Aumann and J. H. Drèze (2008) define a rational expectation of a player i in a game G as the expected payo of some type of i in some belief system for G in which common knowledge of rationality and common priors obtain. Our goal is to characterize the set of rational expectations in terms of the game's payoff matrix. We provide such a characterization for a specific class of strategic games, called semi-elementary, which includes Myerson's "elementary" games.

  1. Lebesgue Sets Immeasurable Existence

    Directory of Open Access Journals (Sweden)

    Diana Marginean Petrovai

    2012-12-01

    Full Text Available It is well known that the notion of measure and integral were released early enough in close connection with practical problems of measuring of geometric figures. Notion of measure was outlined in the early 20th century through H. Lebesgue’s research, founder of the modern theory of measure and integral. It was developed concurrently a technique of integration of functions. Gradually it was formed a specific area todaycalled the measure and integral theory. Essential contributions to building this theory was made by a large number of mathematicians: C. Carathodory, J. Radon, O. Nikodym, S. Bochner, J. Pettis, P. Halmos and many others. In the following we present several abstract sets, classes of sets. There exists the sets which are not Lebesgue measurable and the sets which are Lebesgue measurable but are not Borel measurable. Hence B ⊂ L ⊂ P(X.

  2. Leadership set-up

    DEFF Research Database (Denmark)

    Thude, Bettina Ravnborg; Stenager, Egon; von Plessen, Christian

    2018-01-01

    . Findings: The study found that the leadership set-up did not have any clear influence on interdisciplinary cooperation, as all wards had a high degree of interdisciplinary cooperation independent of which leadership set-up they had. Instead, the authors found a relation between leadership set-up and leader...... could influence legitimacy. Originality/value: The study shows that leadership set-up is not the predominant factor that creates interdisciplinary cooperation; but rather, leader legitimacy also should be considered. Additionally, the study shows that leader legitimacy can be difficult to establish...... and that it cannot be taken for granted. This is something chief executive officers should bear in mind when they plan and implement new leadership structures. Therefore, it would also be useful to look more closely at how to achieve legitimacy in cases where the leader is from a different profession to the staff....

  3. General Paleoclimatology Data Sets

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Data of past climate and environment derived from unusual proxy evidence. Parameter keywords describe what was measured in this data set. Additional summary...

  4. HEDIS Limited Data Set

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Healthcare Effectiveness Data and Information Set (HEDIS) is a tool used by more than 90 percent of Americas health plans to measure performance on important...

  5. Set theory and physics

    Energy Technology Data Exchange (ETDEWEB)

    Svozil, K. [Univ. of Technology, Vienna (Austria)

    1995-11-01

    Inasmuch as physical theories are formalizable, set theory provides a framework for theoretical physics. Four speculations about the relevance of set theoretical modeling for physics are presented: the role of transcendental set theory (i) in chaos theory, (ii) for paradoxical decompositions of solid three-dimensional objects, (iii) in the theory of effective computability (Church-Turing thesis) related to the possible {open_quotes}solution of supertasks,{close_quotes} and (iv) for weak solutions. Several approaches to set theory and their advantages and disadvantages for physical applications are discussed: Cantorian {open_quotes}naive{close_quotes} (i.e., nonaxiomatic) set theory, contructivism, and operationalism. In the author`s opinion, an attitude, of {open_quotes}suspended attention{close_quotes} (a term borrowed from psychoanalysis) seems most promising for progress. Physical and set theoretical entities must be operationalized wherever possible. At the same time, physicists should be open to {open_quotes}bizarre{close_quotes} or {open_quotes}mindboggling{close_quotes} new formalisms, which need not be operationalizable or testable at the time of their creation, but which may successfully lead to novel fields of phenomenology and technology.

  6. Gap sequence, Lipschitz equivalence and box dimension of fractal sets

    International Nuclear Information System (INIS)

    Rao Hui; Yang Yamin; Ruan Huojun

    2008-01-01

    We introduce a notion of gap sequences for compact sets E subset of R d , which is a generalization of the gap sequences of compact sets on the real line. We show that if the gap sequences of two fractal sets are not equivalent, then these two sets cannot be Lipschitz equivalent, where the latter fact is usually very hard to verify. Finally, we show that for some typical fractal sets, the gap sequences characterize the upper box dimension

  7. Protein folding: Defining a standard set of experimental conditions and a preliminary kinetic data set of two-state proteins

    DEFF Research Database (Denmark)

    Maxwell, Karen L.; Wildes, D.; Zarrine-Afsar, A.

    2005-01-01

    Recent years have seen the publication of both empirical and theoretical relationships predicting the rates with which proteins fold. Our ability to test and refine these relationships has been limited, however, by a variety of difficulties associated with the comparison of folding and unfolding ...... efforts is to set uniform standards for the experimental community and to initiate an accumulating, self-consistent data set that will aid ongoing efforts to understand the folding process....... constructs. The lack of a single approach to data analysis and error estimation, or even of a common set of units and reporting standards, further hinders comparative studies of folding. In an effort to overcome these problems, we define here a consensus set of experimental conditions (25°C at pH 7.0, 50 m...... rates, thermodynamics, and structure across diverse sets of proteins. These difficulties include the wide, potentially confounding range of experimental conditions and methods employed to date and the difficulty of obtaining correct and complete sequence and structural details for the characterized...

  8. X-ray characterization of solid small molecule organic materials

    Science.gov (United States)

    Billinge, Simon; Shankland, Kenneth; Shankland, Norman; Florence, Alastair

    2014-06-10

    The present invention provides, inter alia, methods of characterizing a small molecule organic material, e.g., a drug or a drug product. This method includes subjecting the solid small molecule organic material to x-ray total scattering analysis at a short wavelength, collecting data generated thereby, and mathematically transforming the data to provide a refined set of data.

  9. The Model Confidence Set

    DEFF Research Database (Denmark)

    Hansen, Peter Reinhard; Lunde, Asger; Nason, James M.

    The paper introduces the model confidence set (MCS) and applies it to the selection of models. A MCS is a set of models that is constructed such that it will contain the best model with a given level of confidence. The MCS is in this sense analogous to a confidence interval for a parameter. The MCS......, beyond the comparison of models. We apply the MCS procedure to two empirical problems. First, we revisit the inflation forecasting problem posed by Stock and Watson (1999), and compute the MCS for their set of inflation forecasts. Second, we compare a number of Taylor rule regressions and determine...... the MCS of the best in terms of in-sample likelihood criteria....

  10. Revitalizing the setting approach

    DEFF Research Database (Denmark)

    Bloch, Paul; Toft, Ulla; Reinbach, Helene Christine

    2014-01-01

    BackgroundThe concept of health promotion rests on aspirations aiming at enabling people to increase control over and improve their health. Health promotion action is facilitated in settings such as schools, homes and work places. As a contribution to the promotion of healthy lifestyles, we have ...... approach is based on ecological and whole-systems thinking, and stipulates important principles and values of integration, participation, empowerment, context and knowledge-based development....... further developed the setting approach in an effort to harmonise it with contemporary realities (and complexities) of health promotion and public health action. The paper introduces a modified concept, the supersetting approach, which builds on the optimised use of diverse and valuable resources embedded...... in local community settings and on the strengths of social interaction and local ownership as drivers of change processes. Interventions based on a supersetting approach are first and foremost characterised by being integrated, but also participatory, empowering, context-sensitive and knowledge...

  11. Set theory and logic

    CERN Document Server

    Stoll, Robert R

    1979-01-01

    Set Theory and Logic is the result of a course of lectures for advanced undergraduates, developed at Oberlin College for the purpose of introducing students to the conceptual foundations of mathematics. Mathematics, specifically the real number system, is approached as a unity whose operations can be logically ordered through axioms. One of the most complex and essential of modern mathematical innovations, the theory of sets (crucial to quantum mechanics and other sciences), is introduced in a most careful concept manner, aiming for the maximum in clarity and stimulation for further study in

  12. Nonmeasurable sets and functions

    CERN Document Server

    Kharazishvili, Alexander

    2004-01-01

    The book is devoted to various constructions of sets which are nonmeasurable with respect to invariant (more generally, quasi-invariant) measures. Our starting point is the classical Vitali theorem stating the existence of subsets of the real line which are not measurable in the Lebesgue sense. This theorem stimulated the development of the following interesting topics in mathematics:1. Paradoxical decompositions of sets in finite-dimensional Euclidean spaces;2. The theory of non-real-valued-measurable cardinals;3. The theory of invariant (quasi-invariant)extensions of invariant (quasi-invaria

  13. Why quasi-sets?

    Directory of Open Access Journals (Sweden)

    Décio Krause

    2002-11-01

    Full Text Available Quasi-set theory was developed to deal with collections of indistinguishable objects. In standard mathematics, there are no such kind of entities, for indistinguishability (agreement with respect to all properties entails numerical identity. The main motivation underlying such a theory is of course quantum physics, for collections of indistinguishable (’identical’ in the physicists’ jargon particles cannot be regarded as ’sets’ of standard set theories, which are collections of distinguishable objects. In this paper, a rationale for the development of such a theory is presented, motivated by Heinz Post’s claim that indistinguishability ofquantum entities should be attributed ’right at the start’.

  14. Combinatorics of finite sets

    CERN Document Server

    Anderson, Ian

    2011-01-01

    Coherent treatment provides comprehensive view of basic methods and results of the combinatorial study of finite set systems. The Clements-Lindstrom extension of the Kruskal-Katona theorem to multisets is explored, as is the Greene-Kleitman result concerning k-saturated chain partitions of general partially ordered sets. Connections with Dilworth's theorem, the marriage problem, and probability are also discussed. Each chapter ends with a helpful series of exercises and outline solutions appear at the end. ""An excellent text for a topics course in discrete mathematics."" - Bulletin of the Ame

  15. Prices and Price Setting

    NARCIS (Netherlands)

    R.P. Faber (Riemer)

    2010-01-01

    textabstractThis thesis studies price data and tries to unravel the underlying economic processes of why firms have chosen these prices. It focuses on three aspects of price setting. First, it studies whether the existence of a suggested price has a coordinating effect on the prices of firms.

  16. Cobham recursive set functions

    Czech Academy of Sciences Publication Activity Database

    Beckmann, A.; Buss, S.; Friedman, S.-D.; Müller, M.; Thapen, Neil

    2016-01-01

    Roč. 167, č. 3 (2016), s. 335-369 ISSN 0168-0072 R&D Projects: GA ČR GBP202/12/G061 Institutional support: RVO:67985840 Keywords : set function * polynomial time * Cobham recursion Subject RIV: BA - General Mathematics Impact factor: 0.647, year: 2016 http://www.sciencedirect.com/science/article/pii/S0168007215001293

  17. SET-Routes programme

    CERN Multimedia

    Marietta Schupp, EMBL Photolab

    2008-01-01

    Dr Sabine Hentze, specialist in human genetics, giving an Insight Lecture entitled "Human Genetics – Diagnostics, Indications and Ethical Issues" on 23 September 2008 at EMBL Heidelberg. Activities in a achool in Budapest during a visit of Angela Bekesi, Ambassadors for the SET-Routes programme.

  18. The Crystal Set

    Science.gov (United States)

    Greenslade, Thomas B., Jr.

    2014-01-01

    In past issues of this journal, the late H. R. Crane wrote a long series of articles under the running title of "How Things Work." In them, Dick dealt with many questions that physics teachers asked themselves, but did not have the time to answer. This article is my attempt to work through the physics of the crystal set, which I thought…

  19. State-set branching

    DEFF Research Database (Denmark)

    Jensen, Rune Møller; Veloso, Manuela M.; Bryant, Randal E.

    2008-01-01

    In this article, we present a framework called state-set branching that combines symbolic search based on reduced ordered Binary Decision Diagrams (BDDs) with best-first search, such as A* and greedy best-first search. The framework relies on an extension of these algorithms from expanding a sing...

  20. Generalized rough sets

    International Nuclear Information System (INIS)

    Rady, E.A.; Kozae, A.M.; Abd El-Monsef, M.M.E.

    2004-01-01

    The process of analyzing data under uncertainty is a main goal for many real life problems. Statistical analysis for such data is an interested area for research. The aim of this paper is to introduce a new method concerning the generalization and modification of the rough set theory introduced early by Pawlak [Int. J. Comput. Inform. Sci. 11 (1982) 314

  1. Therapists in Oncology Settings

    Science.gov (United States)

    Hendrick, Susan S.

    2013-01-01

    This article describes the author's experiences of working with cancer patients/survivors both individually and in support groups for many years, across several settings. It also documents current best-practice guidelines for the psychosocial treatment of cancer patients/survivors and their families. The author's view of the important qualities…

  2. Exploring the level sets of quantum control landscapes

    International Nuclear Information System (INIS)

    Rothman, Adam; Ho, Tak-San; Rabitz, Herschel

    2006-01-01

    A quantum control landscape is defined by the value of a physical observable as a functional of the time-dependent control field E(t) for a given quantum-mechanical system. Level sets through this landscape are prescribed by a particular value of the target observable at the final dynamical time T, regardless of the intervening dynamics. We present a technique for exploring a landscape level set, where a scalar variable s is introduced to characterize trajectories along these level sets. The control fields E(s,t) accomplishing this exploration (i.e., that produce the same value of the target observable for a given system) are determined by solving a differential equation over s in conjunction with the time-dependent Schroedinger equation. There is full freedom to traverse a level set, and a particular trajectory is realized by making an a priori choice for a continuous function f(s,t) that appears in the differential equation for the control field. The continuous function f(s,t) can assume an arbitrary form, and thus a level set generally contains a family of controls, where each control takes the quantum system to the same final target value, but produces a distinct control mechanism. In addition, although the observable value remains invariant over the level set, other dynamical properties (e.g., the degree of robustness to control noise) are not specifically preserved and can vary greatly. Examples are presented to illustrate the continuous nature of level-set controls and their associated induced dynamical features, including continuously morphing mechanisms for population control in model quantum systems

  3. Probabilistic Open Set Recognition

    Science.gov (United States)

    Jain, Lalit Prithviraj

    Real-world tasks in computer vision, pattern recognition and machine learning often touch upon the open set recognition problem: multi-class recognition with incomplete knowledge of the world and many unknown inputs. An obvious way to approach such problems is to develop a recognition system that thresholds probabilities to reject unknown classes. Traditional rejection techniques are not about the unknown; they are about the uncertain boundary and rejection around that boundary. Thus traditional techniques only represent the "known unknowns". However, a proper open set recognition algorithm is needed to reduce the risk from the "unknown unknowns". This dissertation examines this concept and finds existing probabilistic multi-class recognition approaches are ineffective for true open set recognition. We hypothesize the cause is due to weak adhoc assumptions combined with closed-world assumptions made by existing calibration techniques. Intuitively, if we could accurately model just the positive data for any known class without overfitting, we could reject the large set of unknown classes even under this assumption of incomplete class knowledge. For this, we formulate the problem as one of modeling positive training data by invoking statistical extreme value theory (EVT) near the decision boundary of positive data with respect to negative data. We provide a new algorithm called the PI-SVM for estimating the unnormalized posterior probability of class inclusion. This dissertation also introduces a new open set recognition model called Compact Abating Probability (CAP), where the probability of class membership decreases in value (abates) as points move from known data toward open space. We show that CAP models improve open set recognition for multiple algorithms. Leveraging the CAP formulation, we go on to describe the novel Weibull-calibrated SVM (W-SVM) algorithm, which combines the useful properties of statistical EVT for score calibration with one-class and binary

  4. BORDERLINE PERSONALITY DISORDER IN THE MEDICAL SETTING: Suggestive Behaviors, Syndromes, and Diagnoses.

    Science.gov (United States)

    Sansone, Randy A; Sansone, Lori A

    2015-01-01

    Borderline personality disorder is a personality dysfunction that is characterized by disinhibition and impulsivity, which oftentimes manifest as self-regulation difficulties. Patients with this disorder have always been present in medical settings, but have been described as "difficult patients" rather than patients with borderline personality disorder. According to empirical findings, a number of behaviors and medical syndromes/diagnoses are suggestive of borderline personality disorder. Suggestive behaviors in the medical setting may include aggressive or disruptive behaviors, the intentional sabotage of medical care, and excessive healthcare utilization. Suggestive medical syndromes and diagnoses in the medical setting may include alcohol and substance misuse (including the abuse of prescription medications), multiple somatic complaints, chronic pain, obesity, sexual impulsivity, and hair pulling. While not all-inclusive or diagnostic, these behaviors and syndromes/diagnoses may invite further clinical evaluation of the patient for borderline personality disorder.

  5. Food systems in correctional settings

    DEFF Research Database (Denmark)

    Smoyer, Amy; Kjær Minke, Linda

    management of food systems may improve outcomes for incarcerated people and help correctional administrators to maximize their health and safety. This report summarizes existing research on food systems in correctional settings and provides examples of food programmes in prison and remand facilities......Food is a central component of life in correctional institutions and plays a critical role in the physical and mental health of incarcerated people and the construction of prisoners' identities and relationships. An understanding of the role of food in correctional settings and the effective......, including a case study of food-related innovation in the Danish correctional system. It offers specific conclusions for policy-makers, administrators of correctional institutions and prison-food-service professionals, and makes proposals for future research....

  6. Isolation and characterization of a first set of nine polymorphic ...

    Indian Academy of Sciences (India)

    2014-08-12

    Aug 12, 2014 ... efficient conservation and utilization of genetic resources. A number of ... Capital Territory (NCT) of Delhi and other Indian states. Microsatellite loci ... PCR reaction buffer, 0.2 mM dNTPs, and 500 ng template. DNA, 1 U Taq ...

  7. Frame scaling function sets and frame wavelet sets in Rd

    International Nuclear Information System (INIS)

    Liu Zhanwei; Hu Guoen; Wu Guochang

    2009-01-01

    In this paper, we classify frame wavelet sets and frame scaling function sets in higher dimensions. Firstly, we obtain a necessary condition for a set to be the frame wavelet sets. Then, we present a necessary and sufficient condition for a set to be a frame scaling function set. We give a property of frame scaling function sets, too. Some corresponding examples are given to prove our theory in each section.

  8. Agenda Setting and Mass Communication Theory.

    Science.gov (United States)

    Shaw, Eugene F.

    The agenda-setting concept in mass communication asserts that the news media determine what people will include or exclude in their cognition of public events. Findings in uses and gratification research provide the foundation for this concept: an initial focus on people's needs, particularly the need for information. The agenda-setting concept…

  9. On Setting Priorities among Human Rights

    NARCIS (Netherlands)

    Philips, Jos

    2014-01-01

    Should conflicts among human rights be dealt with by including general principles for priority setting at some prominent place in the practice of human rights? This essay argues that neither setting prominent and principled priorities nor a case-by-case approach are likely to be defensible as

  10. Setting Goals for Achievement in Physical Education Settings

    Science.gov (United States)

    Baghurst, Timothy; Tapps, Tyler; Kensinger, Weston

    2015-01-01

    Goal setting has been shown to improve student performance, motivation, and task completion in academic settings. Although goal setting is utilized by many education professionals to help students set realistic and proper goals, physical educators may not be using goal setting effectively. Without incorporating all three types of goals and…

  11. A Guide to Running a Recycling Project. [Includes Recycling Handbook].

    Science.gov (United States)

    Oregon Recycling Information and Organizing Network, Portland.

    This guide, designed for both students and adults, is intended for individuals who feel they might be interested in establishing a recycling depot. The guide includes such pertinent information as deciding how to set up a depot, markets and transportation, preparation of materials, where to place the depot and when to operate it, publicity and…

  12. Interviewing Objects: Including Educational Technologies as Qualitative Research Participants

    Science.gov (United States)

    Adams, Catherine A.; Thompson, Terrie Lynn

    2011-01-01

    This article argues the importance of including significant technologies-in-use as key qualitative research participants when studying today's digitally enhanced learning environments. We gather a set of eight heuristics to assist qualitative researchers in "interviewing" technologies-in-use (or other relevant objects), drawing on concrete…

  13. Potential-based methodology for active sound control in three dimensional settings

    OpenAIRE

    Lim, H.; Utyuzhnikov, S V; Lam, Y.W.; Kelly, L.

    2014-01-01

    This paper extends a potential-based approach to active noise shielding with preservation of wanted sound in three-dimensional settings. The approach, which was described in a previous publication [Lim et al., J. Acoust. Soc. Am. 129(2), 717–725 (2011)], provides several significant advantages over conventional noise control methods. Most significantly, the methodology does not require any information including the characterization of sources, impedance boundary conditions and surrounding med...

  14. Psychiatric diagnosis in legal settings

    Directory of Open Access Journals (Sweden)

    Alfred Allan

    2005-12-01

    Full Text Available When asked to give a diagnosis in legal settings practitioners should be mindful of the tentative nature of psychiatric diag- noses and that courts require that such a diagnosis must have scientific credibility. South African courts are not explicit about the test they will apply to determine whether a diagno- sis is scientifically credible, but some guidance can be found in United States case law. This paper examines these criteria with reference to the disorders included in the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR.

  15. Alertness management : strategic naps in operational settings

    Science.gov (United States)

    1995-01-01

    Managing fatigue in complex operational settings requires attention to multiple factors, including hours of service, scheduling, education and training, countermeasures, technology, and research. Alertness-management strategies can be used to promote...

  16. Health Outcomes Survey - Limited Data Set

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Medicare Health Outcomes Survey (HOS) limited data sets (LDS) are comprised of the entire national sample for a given 2-year cohort (including both respondents...

  17. Social Set Visualizer

    DEFF Research Database (Denmark)

    Flesch, Benjamin; Hussain, Abid; Vatrapu, Ravi

    2015-01-01

    -edge open source visual analytics libraries from D3.js and creation of new visualizations (ac-tor mobility across time, conversational comets etc). Evaluation of the dashboard consisting of technical testing, usability testing, and domain-specific testing with CSR students and yielded positive results.......This paper presents a state-of-the art visual analytics dash-board, Social Set Visualizer (SoSeVi), of approximately 90 million Facebook actions from 11 different companies that have been mentioned in the traditional media in relation to garment factory accidents in Bangladesh. The enterprise...

  18. Social Set Analysis

    DEFF Research Database (Denmark)

    Vatrapu, Ravi; Hussain, Abid; Buus Lassen, Niels

    2015-01-01

    of Facebook or Twitter data. However, there exist no other holistic computational social science approach beyond the relational sociology and graph theory of SNA. To address this limitation, this paper presents an alternative holistic approach to Big Social Data analytics called Social Set Analysis (SSA......This paper argues that the basic premise of Social Network Analysis (SNA) -- namely that social reality is constituted by dyadic relations and that social interactions are determined by structural properties of networks-- is neither necessary nor sufficient, for Big Social Data analytics...

  19. Markov set-chains

    CERN Document Server

    Hartfiel, Darald J

    1998-01-01

    In this study extending classical Markov chain theory to handle fluctuating transition matrices, the author develops a theory of Markov set-chains and provides numerous examples showing how that theory can be applied. Chapters are concluded with a discussion of related research. Readers who can benefit from this monograph are those interested in, or involved with, systems whose data is imprecise or that fluctuate with time. A background equivalent to a course in linear algebra and one in probability theory should be sufficient.

  20. Analyzing ROC curves using the effective set-size model

    Science.gov (United States)

    Samuelson, Frank W.; Abbey, Craig K.; He, Xin

    2018-03-01

    The Effective Set-Size model has been used to describe uncertainty in various signal detection experiments. The model regards images as if they were an effective number (M*) of searchable locations, where the observer treats each location as a location-known-exactly detection task with signals having average detectability d'. The model assumes a rational observer behaves as if he searches an effective number of independent locations and follows signal detection theory at each location. Thus the location-known-exactly detectability (d') and the effective number of independent locations M* fully characterize search performance. In this model the image rating in a single-response task is assumed to be the maximum response that the observer would assign to these many locations. The model has been used by a number of other researchers, and is well corroborated. We examine this model as a way of differentiating imaging tasks that radiologists perform. Tasks involving more searching or location uncertainty may have higher estimated M* values. In this work we applied the Effective Set-Size model to a number of medical imaging data sets. The data sets include radiologists reading screening and diagnostic mammography with and without computer-aided diagnosis (CAD), and breast tomosynthesis. We developed an algorithm to fit the model parameters using two-sample maximum-likelihood ordinal regression, similar to the classic bi-normal model. The resulting model ROC curves are rational and fit the observed data well. We find that the distributions of M* and d' differ significantly among these data sets, and differ between pairs of imaging systems within studies. For example, on average tomosynthesis increased readers' d' values, while CAD reduced the M* parameters. We demonstrate that the model parameters M* and d' are correlated. We conclude that the Effective Set-Size model may be a useful way of differentiating location uncertainty from the diagnostic uncertainty in medical

  1. Atomic and vibrational origins of mechanical toughness in bioactive cement during setting

    DEFF Research Database (Denmark)

    Tian, Kun V.; Yang, Bin; Yue, Yuanzheng

    2015-01-01

    Bioactive glass ionomer cements (GICs) have been in widespread use for B40 years in dentistry and medicine. However, these composites fall short of the toughness needed for permanent implants. Significant impediment to improvement has been the requisite use of conventional destructive mechanical...... interfacial configurations. Contrary to convention, we find setting is non-monotonic, characterized by abrupt features not previously detected, including a glass–polymer coupling point, an early setting point, where decreasing toughness unexpectedly recovers, followed by stress-induced weakening of interfaces...

  2. A Set Theoretical Approach to Maturity Models

    DEFF Research Database (Denmark)

    Lasrado, Lester; Vatrapu, Ravi; Andersen, Kim Normann

    2016-01-01

    characterized by equifinality, multiple conjunctural causation, and case diversity. We prescribe methodological guidelines consisting of a six-step procedure to systematically apply set theoretic methods to conceptualize, develop, and empirically derive maturity models and provide a demonstration......Maturity Model research in IS has been criticized for the lack of theoretical grounding, methodological rigor, empirical validations, and ignorance of multiple and non-linear paths to maturity. To address these criticisms, this paper proposes a novel set-theoretical approach to maturity models...

  3. Theoretical Characterization of Enclosures

    Czech Academy of Sciences Publication Activity Database

    Rohn, Jiří

    2016-01-01

    Roč. 21, October (2016), s. 140-145 ISSN 1573-1340 Institutional support: RVO:67985807 Keywords : interval linear equations * solution set * enclosure * component * characterization Subject RIV: BA - General Mathematics http://interval.louisiana.edu/reliable-computing-journal/volume-21/reliable-computing-21-pp-140-145.pdf

  4. Analysis of successive data sets

    NARCIS (Netherlands)

    Spreeuwers, Lieuwe Jan; Breeuwer, Marcel; Haselhoff, Eltjo Hans

    2008-01-01

    The invention relates to the analysis of successive data sets. A local intensity variation is formed from such successive data sets, that is, from data values in successive data sets at corresponding positions in each of the data sets. A region of interest is localized in the individual data sets on

  5. Analysis of successive data sets

    NARCIS (Netherlands)

    Spreeuwers, Lieuwe Jan; Breeuwer, Marcel; Haselhoff, Eltjo Hans

    2002-01-01

    The invention relates to the analysis of successive data sets. A local intensity variation is formed from such successive data sets, that is, from data values in successive data sets at corresponding positions in each of the data sets. A region of interest is localized in the individual data sets on

  6. 42 CFR 410.100 - Included services.

    Science.gov (United States)

    2010-10-01

    ... service; however, maintenance therapy itself is not covered as part of these services. (c) Occupational... increase respiratory function, such as graded activity services; these services include physiologic... rehabilitation plan of treatment, including physical therapy services, occupational therapy services, speech...

  7. An historical and geographic data set on the distribution of macroinvertebrates in Italian mountain lakes

    Directory of Open Access Journals (Sweden)

    Angela Boggero

    2017-11-01

    Full Text Available Macroinvertebrates play a key role in freshwater food webs, acting as major links between organic matter resources, primary consumers (such as bacteria, and secondary consumers (e.g.fish, amphibians, birds, and reptiles. In this paper we present a data set encompassing all geographic and historical data available on macroinvertebrates of the Italian mountain lakes from 1902 to 2016. The data set, divided per Italian mountain range (Alps and Apennines and administrative region, covers more than a century of studies of many foreign and Italian scientists. The data set includes 2372 records and shows macroinvertebrate occurrence data in 176 Alpine and in 13 Apennine lakes, of which 178 of natural origin, 5 reservoirs, and 6 artificially extended. The data set lists 605 taxa, updated on the basis of their current taxonomic position. Only 353 taxa are identified at species level, highlighting the still poorly investigated biodiversity of Italian mountain lake macroinvertebrates. Since they function as key elements to characterize lake ecological status, our data set emphasizes the huge taxonomic effort that still has to be undertaken to fully characterize these ecosystems. The data set is available in csv (comma-separated values format.

  8. Static, Lightweight Includes Resolution for PHP

    NARCIS (Netherlands)

    M.A. Hills (Mark); P. Klint (Paul); J.J. Vinju (Jurgen)

    2014-01-01

    htmlabstractDynamic languages include a number of features that are challenging to model properly in static analysis tools. In PHP, one of these features is the include expression, where an arbitrary expression provides the path of the file to include at runtime. In this paper we present two

  9. Article Including Environmental Barrier Coating System

    Science.gov (United States)

    Lee, Kang N. (Inventor)

    2015-01-01

    An enhanced environmental barrier coating for a silicon containing substrate. The enhanced barrier coating may include a bond coat doped with at least one of an alkali metal oxide and an alkali earth metal oxide. The enhanced barrier coating may include a composite mullite bond coat including BSAS and another distinct second phase oxide applied over said surface.

  10. Rare thoracic cancers, including peritoneum mesothelioma

    NARCIS (Netherlands)

    Siesling, Sabine; van der Zwan, Jan Maarten; Izarzugaza, Isabel; Jaal, Jana; Treasure, Tom; Foschi, Roberto; Ricardi, Umberto; Groen, Harry; Tavilla, Andrea; Ardanaz, Eva

    Rare thoracic cancers include those of the trachea, thymus and mesothelioma (including peritoneum mesothelioma). The aim of this study was to describe the incidence, prevalence and survival of rare thoracic tumours using a large database, which includes cancer patients diagnosed from 1978 to 2002,

  11. Rare thoracic cancers, including peritoneum mesothelioma

    NARCIS (Netherlands)

    Siesling, Sabine; Zwan, J.M.V.D.; Izarzugaza, I.; Jaal, J.; Treasure, T.; Foschi, R.; Ricardi, U.; Groen, H.; Tavilla, A.; Ardanaz, E.

    2012-01-01

    Rare thoracic cancers include those of the trachea, thymus and mesothelioma (including peritoneum mesothelioma). The aim of this study was to describe the incidence, prevalence and survival of rare thoracic tumours using a large database, which includes cancer patients diagnosed from 1978 to 2002,

  12. Exploring nurses' and patients' perspectives of limit setting in a forensic mental health setting.

    Science.gov (United States)

    Maguire, Tessa; Daffern, Michael; Martin, Trish

    2014-04-01

    Limit setting is an intervention that is frequently used by mental health nurses. However, limit setting is poorly conceptualized, its purpose is unclear, and there are few evidence-based guidelines to assist nurses to set limits in a safe and effective manner. What is known is that the manner in which nurses set limits influences patients' perceptions of the interactions and their emotional and behavioural responses. In this qualitative study, 12 nurses and 12 patients participated in personal, semistructured interviews that aimed to explore limit setting and to propose principles to guide practice. The findings suggested that: (i) limit setting is important to safety in mental health hospitals; (ii) engaging patients in an empathic manner is necessary when setting limits (when nurses engage in an empathic manner, the therapeutic relationship is more likely to be preserved and the risk of aggressive responses is reduced); and (iii) an authoritative (fair, respectful, consistent, and knowledgeable), rather than authoritarian (controlling and indifferent), limit-setting style enhances positive outcomes with regards to adherence, reduced likelihood of aggression, and preservation of the therapeutic relationship. In conclusion, a limit-setting style characterized by empathic responding and an authoritative, rather than authoritarian interpersonal, style is recommended. Elucidating the components of this style is critical for effective training and best practice of mental health nurses, and to reduce aggressive responses from limit setting. © 2013 Australian College of Mental Health Nurses Inc.

  13. Dynamical basis set

    International Nuclear Information System (INIS)

    Blanco, M.; Heller, E.J.

    1985-01-01

    A new Cartesian basis set is defined that is suitable for the representation of molecular vibration-rotation bound states. The Cartesian basis functions are superpositions of semiclassical states generated through the use of classical trajectories that conform to the intrinsic dynamics of the molecule. Although semiclassical input is employed, the method becomes ab initio through the standard matrix diagonalization variational method. Special attention is given to classical-quantum correspondences for angular momentum. In particular, it is shown that the use of semiclassical information preferentially leads to angular momentum eigenstates with magnetic quantum number Vertical BarMVertical Bar equal to the total angular momentum J. The present method offers a reliable technique for representing highly excited vibrational-rotational states where perturbation techniques are no longer applicable

  14. Matched pairs approach to set theoretic solutions of the Yang-Baxter equation

    International Nuclear Information System (INIS)

    Gateva-Ivanova, T.; Majid, S.

    2005-08-01

    We study set-theoretic solutions (X,r) of the Yang-Baxter equations on a set X in terms of the induced left and right actions of X on itself. We give a characterization of involutive square-free solutions in terms of cyclicity conditions. We characterise general solutions in terms of an induced matched pair of unital semigroups S(X,r) and construct (S,r S ) from the matched pair. Finally, we study extensions of solutions in terms of matched pairs of their associated semigroups. We also prove several general results about matched pairs of unital semigroups of the required type, including iterated products S bowtie S bowtie S underlying the proof that r S is a solution, and extensions (S bowtie T, r Sb owtie T ). Examples include a general 'double' construction (S bowtie S,r Sb owtie S ) and some concrete extensions, their actions and graphs based on small sets. (author)

  15. LEDA LLRF control system characterization

    International Nuclear Information System (INIS)

    Regan, A.H.; Balleyguier, P.; Ziomek, C.D.

    1998-01-01

    The Low Energy Demonstration Accelerator (LEDA) for the Accelerator for the Production of Tritium (APT) project will be built at Los Alamos National Laboratory. The low-level RF (LLRF) control system portion of this accelerator must perform many functions, of which the primary one is controlling the RF fields in the accelerating cavities. Plans have been made to provide for on-line characterization of the LLRF control system and the complete RF system through use of stimulus and response buffers, and a digital signal processor built into the field control system electronics. The purpose of this circuitry is to characterize the behavior of the entire RF system (klystron, waveguides, high power splitters, accelerator cavity, etc.). This characterization feature can be used to measure the performance of the closed loop system with respect to the open loop system, to provide an automated way to set loop parameters, to determine the cavity Q-curve, and to detect any abnormal behavior in the RF chain. The types of measurements include frequency and time-domain responses to given perturbations, amplitude modulations, etc. This paper will discuss types of algorithms that can be implemented and present a description and block diagram of the electronics to be used

  16. A modal characterization of Peirce algebras

    NARCIS (Netherlands)

    M. de Rijke (Maarten)

    1995-01-01

    textabstractPeirce algebras combine sets, relations and various operations linking the two in a unifying setting.This note offers a modal perspective on Peirce algebras.It uses modal logic to characterize the full Peirce algebras.

  17. Permanent magnets including undulators and wigglers

    CERN Document Server

    Bahrdt, J

    2010-01-01

    After a few historic remarks on magnetic materials we introduce the basic definitions related to permanent magnets. The magnetic properties of the most common materials are reviewed and the production processes are described. Measurement techniques for the characterization of macroscopic and microscopic properties of permanent magnets are presented. Field simulation techniques for permanent magnet devices are discussed. Today, permanent magnets are used in many fields. This article concentrates on the applications of permanent magnets in accelerators starting from dipoles and quadrupoles on to wigglers and undulators.

  18. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Science.gov (United States)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    purity of the final preparation. Using mini-gels (BioRad Mini-Protean II apparatus), each group can pour, run, and stain their own 8 7.3-cm gel within the lab period; destaining can be carried out at any time afterward. The main contaminating band observed is ovalbumin, at a molecular weight of 46,000. Computer Modeling Using the program Quanta (MSI, Burlington, MA) on Indigo workstations (Silicon Graphics, Hudson, MA), the students retrieve coordinates from an MSI version of the Protein Data Bank, display the structure, and rationalize what changes would occur with a mutated form of the protein. Even for those who do not have Quanta or analogous programs, structural coordinates are available through the Internet. Students are prepared for their independent use of the molecular modeling workstations through a series of tutorials during the course of the semester. These exercises require that the students become familiar with specific applications of Quanta, including setting secondary conformation and hydrogen bonds, energy calculations, selectively displaying parts of molecules, measuring interatomic distances, and editing existing proteins. This introduction to macromolecular modeling is comparable to that suggested by Harvey and Tan (17) as a brief introduction to the field. Peer Review For each writing assignment (short paper and grant proposal), one week of lab is devoted to the peer review process. Students are to come to lab with a draft of their paper and a cover letter to their reviewers, which states how far they believe they are in the writing process; what they like and don't like about their work at this stage; and in what specific areas they need help (e.g., audience level, organization, use of references). They exchange papers, reading two or three during the course of the lab period. For each paper, they fill out a peer review form, which requires that they summarize the paper; look for clarity of presentation, appropriate citations, and use of others

  19. Ready, set, move!

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    This year, the CERN Medical Service is launching a new public health campaign. Advertised by the catchphrase “Move! & Eat Better”, the particular aim of the campaign is to encourage people at CERN to take more regular exercise, of whatever kind.   The CERN annual relay race is scheduled on 24 May this year. The CERN Medical Service will officially launch its “Move! & Eat Better” campaign at this popular sporting event. “We shall be on hand on the day of the race to strongly advocate regular physical activity,” explains Rachid Belkheir, one of the Medical Service doctors. "We really want to pitch our campaign and answer any questions people may have. Above all we want to set an example. So we are going to walk the same circuit as the runners to underline to people that they can easily incorporate movement into their daily routine.” An underlying concern has prompted this campaign: during their first few year...

  20. Goal-setting in clinical medicine.

    Science.gov (United States)

    Bradley, E H; Bogardus, S T; Tinetti, M E; Inouye, S K

    1999-07-01

    The process of setting goals for medical care in the context of chronic disease has received little attention in the medical literature, despite the importance of goal-setting in the achievement of desired outcomes. Using qualitative research methods, this paper develops a theory of goal-setting in the care of patients with dementia. The theory posits several propositions. First, goals are generated from embedded values but are distinct from values. Goals vary based on specific circumstances and alternatives whereas values are person-specific and relatively stable in the face of changing circumstances. Second, goals are hierarchical in nature, with complex mappings between general and specific goals. Third, there are a number of factors that modify the goal-setting process, by affecting the generation of goals from values or the translation of general goals to specific goals. Modifying factors related to individuals include their degree of risk-taking, perceived self-efficacy, and acceptance of the disease. Disease factors that modify the goal-setting process include the urgency and irreversibility of the medical condition. Pertinent characteristics of the patient-family-clinician interaction include the level of participation, control, and trust among patients, family members, and clinicians. The research suggests that the goal-setting process in clinical medicine is complex, and the potential for disagreements regarding goals substantial. The nature of the goal-setting process suggests that explicit discussion of goals for care may be necessary to promote effective patient-family-clinician communication and adequate care planning.

  1. Estimating the CCSD basis-set limit energy from small basis sets: basis-set extrapolations vs additivity schemes

    Energy Technology Data Exchange (ETDEWEB)

    Spackman, Peter R.; Karton, Amir, E-mail: amir.karton@uwa.edu.au [School of Chemistry and Biochemistry, The University of Western Australia, Perth, WA 6009 (Australia)

    2015-05-15

    Coupled cluster calculations with all single and double excitations (CCSD) converge exceedingly slowly with the size of the one-particle basis set. We assess the performance of a number of approaches for obtaining CCSD correlation energies close to the complete basis-set limit in conjunction with relatively small DZ and TZ basis sets. These include global and system-dependent extrapolations based on the A + B/L{sup α} two-point extrapolation formula, and the well-known additivity approach that uses an MP2-based basis-set-correction term. We show that the basis set convergence rate can change dramatically between different systems(e.g.it is slower for molecules with polar bonds and/or second-row elements). The system-dependent basis-set extrapolation scheme, in which unique basis-set extrapolation exponents for each system are obtained from lower-cost MP2 calculations, significantly accelerates the basis-set convergence relative to the global extrapolations. Nevertheless, we find that the simple MP2-based basis-set additivity scheme outperforms the extrapolation approaches. For example, the following root-mean-squared deviations are obtained for the 140 basis-set limit CCSD atomization energies in the W4-11 database: 9.1 (global extrapolation), 3.7 (system-dependent extrapolation), and 2.4 (additivity scheme) kJ mol{sup –1}. The CCSD energy in these approximations is obtained from basis sets of up to TZ quality and the latter two approaches require additional MP2 calculations with basis sets of up to QZ quality. We also assess the performance of the basis-set extrapolations and additivity schemes for a set of 20 basis-set limit CCSD atomization energies of larger molecules including amino acids, DNA/RNA bases, aromatic compounds, and platonic hydrocarbon cages. We obtain the following RMSDs for the above methods: 10.2 (global extrapolation), 5.7 (system-dependent extrapolation), and 2.9 (additivity scheme) kJ mol{sup –1}.

  2. Estimating the CCSD basis-set limit energy from small basis sets: basis-set extrapolations vs additivity schemes

    International Nuclear Information System (INIS)

    Spackman, Peter R.; Karton, Amir

    2015-01-01

    Coupled cluster calculations with all single and double excitations (CCSD) converge exceedingly slowly with the size of the one-particle basis set. We assess the performance of a number of approaches for obtaining CCSD correlation energies close to the complete basis-set limit in conjunction with relatively small DZ and TZ basis sets. These include global and system-dependent extrapolations based on the A + B/L α two-point extrapolation formula, and the well-known additivity approach that uses an MP2-based basis-set-correction term. We show that the basis set convergence rate can change dramatically between different systems(e.g.it is slower for molecules with polar bonds and/or second-row elements). The system-dependent basis-set extrapolation scheme, in which unique basis-set extrapolation exponents for each system are obtained from lower-cost MP2 calculations, significantly accelerates the basis-set convergence relative to the global extrapolations. Nevertheless, we find that the simple MP2-based basis-set additivity scheme outperforms the extrapolation approaches. For example, the following root-mean-squared deviations are obtained for the 140 basis-set limit CCSD atomization energies in the W4-11 database: 9.1 (global extrapolation), 3.7 (system-dependent extrapolation), and 2.4 (additivity scheme) kJ mol –1 . The CCSD energy in these approximations is obtained from basis sets of up to TZ quality and the latter two approaches require additional MP2 calculations with basis sets of up to QZ quality. We also assess the performance of the basis-set extrapolations and additivity schemes for a set of 20 basis-set limit CCSD atomization energies of larger molecules including amino acids, DNA/RNA bases, aromatic compounds, and platonic hydrocarbon cages. We obtain the following RMSDs for the above methods: 10.2 (global extrapolation), 5.7 (system-dependent extrapolation), and 2.9 (additivity scheme) kJ mol –1

  3. HETC-3STEP included fragmentation process

    Energy Technology Data Exchange (ETDEWEB)

    Shigyo, Nobuhiro; Iga, Kiminori; Ishibashi, Kenji [Kyushu Univ., Fukuoka (Japan). Faculty of Engineering

    1997-03-01

    High Energy Transport Code (HETC) based on the cascade-evaporation model is modified to calculate the fragmentation cross section. For the cascade process, nucleon-nucleon cross sections are used for collision computation; effective in-medium-corrected cross sections are adopted instead of the original free-nucleon collision. The exciton model is adopted for improvement of backward nucleon-emission cross section for low-energy nucleon-incident events. The fragmentation reaction is incorporated into the original HETC as a subroutine set by the use of the systematics of the reaction. The modified HETC (HETC-3STEP/FRG) reproduces experimental fragment yields to a reasonable degree. (author)

  4. Extended Set Constraints and Tree Grammar Abstraction of Programs

    DEFF Research Database (Denmark)

    Rosendahl, Mads; Gallagher, John Patrick

    2011-01-01

    Set constraints are relations between sets of ground terms or trees. This paper presents two main contributions: firstly we consider an extension of the systems of set constraints to include a tuple constructor, and secondly we construct a simplified solution procedure for set constraints. We...

  5. Efficient gate set tomography on a multi-qubit superconducting processor

    Science.gov (United States)

    Nielsen, Erik; Rudinger, Kenneth; Blume-Kohout, Robin; Bestwick, Andrew; Bloom, Benjamin; Block, Maxwell; Caldwell, Shane; Curtis, Michael; Hudson, Alex; Orgiazzi, Jean-Luc; Papageorge, Alexander; Polloreno, Anthony; Reagor, Matt; Rubin, Nicholas; Scheer, Michael; Selvanayagam, Michael; Sete, Eyob; Sinclair, Rodney; Smith, Robert; Vahidpour, Mehrnoosh; Villiers, Marius; Zeng, William; Rigetti, Chad

    Quantum information processors with five or more qubits are becoming common. Complete, predictive characterization of such devices e.g. via any form of tomography, including gate set tomography appears impossible because the parameter space is intractably large. Randomized benchmarking scales well, but cannot predict device behavior or diagnose failure modes. We introduce a new type of gate set tomography that uses an efficient ansatz to model physically plausible errors, but scales polynomially with the number of qubits. We will describe the theory behind this multi-qubit tomography and present experimental results from using it to characterize a multi-qubit processor made by Rigetti Quantum Computing. Sandia National Laboratories is a multi-mission laboratory managed and operated by Sandia Corporation, a wholly owned subsidary of Lockheed Martin Corporation, for the US Department of Energy's NNSA under contract DE-AC04-94AL85000.

  6. Structural Studies of the SET Domain from RIZ1 Tumor Suppressor

    Energy Technology Data Exchange (ETDEWEB)

    Briknarova, Klara; Zhou, Xinliang; Satterthwait, Arnold C.; Hoyt, David W.; Ely, Kathryn R.; Huang, Shi

    2008-02-15

    Histone lysine methyltransferases (HKMTs) are involved in regulation of chromatin structure, and, as such, are important for longterm gene activation and repression that is associated with cell memory and establishment of cell-type specific transcriptional programs. Most HKMTs contain a SET domain, which is responsible for their catalytic activity. RIZ1 is a transcription regulator and tumor suppressor that catalyzes methylation of lysine 9 of histone H3 and contains a rather distinct SET domain. Similar SET domains, sometimes refererred to as PR (PRDI-BF1 and RIZ1 homology) domains, are also found in other proteins including Blimp-1/PRDI-BF1, MDS1-EVI1 and Meisetz. We determined the solution structure of the PR domain from RIZ1 and characterized its interaction with S-adenosyl homocysteine (SAH) and a peptide from histone H3. Despite low sequence identity with canonical SET domains, the PR domain displays a typical SET fold including a pseudo-knot at the C-terminus. The N-flanking sequence of RIZ1 PR domain adopts a novel conformation and interacts closely with the SET fold. The C-flanking sequence contains an α-helix that exhibits higher mobility than the SET fold and points away from the protein face that harbors active site in other SET domains. Residues that interact with the methylation cofactor in SET domains are not conserved in RIZ1 or other PR domains, and the SET fold of RIZ1 does not bind SAH. However, the PR domain of RIZ1 interacts specifically with a synthetic peptide comprising residues 1-20 of histone H3.

  7. Soft sets combined with interval valued intuitionistic fuzzy sets of type-2 and rough sets

    Directory of Open Access Journals (Sweden)

    Anjan Mukherjee

    2015-03-01

    Full Text Available Fuzzy set theory, rough set theory and soft set theory are all mathematical tools dealing with uncertainties. The concept of type-2 fuzzy sets was introduced by Zadeh in 1975 which was extended to interval valued intuitionistic fuzzy sets of type-2 by the authors.This paper is devoted to the discussions of the combinations of interval valued intuitionistic sets of type-2, soft sets and rough sets.Three different types of new hybrid models, namely-interval valued intuitionistic fuzzy soft sets of type-2, soft rough interval valued intuitionistic fuzzy sets of type-2 and soft interval valued intuitionistic fuzzy rough sets of type-2 are proposed and their properties are derived.

  8. Hausdorff dimensions for sets with broken scaling symmetry

    International Nuclear Information System (INIS)

    Umberger, D.K.; Mayer-Kress, G.; Jen, E.

    1985-01-01

    Based on Hausdorff's original approach to fractional dimensions, we study systems which are not sufficiently characterized by their ''fractal'' or scaling dimension. We construct informative examples of such sets and relate them to sets observed in the context of dynamical systems. 18 refs., 5 figs

  9. Special set linear algebra and special set fuzzy linear algebra

    OpenAIRE

    Kandasamy, W. B. Vasantha; Smarandache, Florentin; Ilanthenral, K.

    2009-01-01

    The authors in this book introduce the notion of special set linear algebra and special set fuzzy Linear algebra, which is an extension of the notion set linear algebra and set fuzzy linear algebra. These concepts are best suited in the application of multi expert models and cryptology. This book has five chapters. In chapter one the basic concepts about set linear algebra is given in order to make this book a self contained one. The notion of special set linear algebra and their fuzzy analog...

  10. Births and deaths including fetal deaths

    Data.gov (United States)

    U.S. Department of Health & Human Services — Access to a variety of United States birth and death files including fetal deaths: Birth Files, 1968-2009; 1995-2005; Fetal death file, 1982-2005; Mortality files,...

  11. Eastern Hemisphere set for 1991

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Give yourself an edge by acquiring quick access to over 40,000 names and titles of key operating personnel in the industry throughout more than 100 countries in a part of the world which is crucial to international petroleum activity. Both the European Petroleum Directory and the Asia-Pacific/Africa-Middle East Petroleum Directory provide complete names, addresses, personnel, phone numbers, fax numbers, telex numbers, and cable numbers for companies involved in drilling, refining, exploration, pipelines, engineering, field services, construction and many other petroleum-related operations. This book is a source of information for updating mailing lists and prospect files and for shopping for competitive bids on equipment and services. Also provided is the Oil ampersand Gas Journal's Worldwide Production Survey for all the countries included in the set

  12. Including Indigenous Minorities in Decision-Making

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene

    Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand......Based on theories of public sphere participation and deliberative democracy, this book presents empirical results from a study of experiences with including Aboriginal and Maori groups in political decision-making in respectively Western Australia and New Zealand...

  13. Gas storage materials, including hydrogen storage materials

    Science.gov (United States)

    Mohtadi, Rana F; Wicks, George G; Heung, Leung K; Nakamura, Kenji

    2013-02-19

    A material for the storage and release of gases comprises a plurality of hollow elements, each hollow element comprising a porous wall enclosing an interior cavity, the interior cavity including structures of a solid-state storage material. In particular examples, the storage material is a hydrogen storage material such as a solid state hydride. An improved method for forming such materials includes the solution diffusion of a storage material solution through a porous wall of a hollow element into an interior cavity.

  14. Evaluation of integrated data sets: four examples

    International Nuclear Information System (INIS)

    Bolivar, S.L.; Freeman, S.B.; Weaver, T.A.

    1982-01-01

    Several large data sets have been integrated and utilized for rapid evaluation on a reconnaissance scale for the Montrose 1 0 x 2 0 quadrangle, Colorado. The data sets include Landsat imagery, hydrogeochemical and stream sediment analyses, airborne geophysical data, known mineral occurrences, and a geologic map. All data sets were registered to a 179 x 119 rectangular grid and projected onto Universal Transverse Mercator coordinates. A grid resolution of 1 km was used. All possible combinations of three, for most data sets, were examined for general geologic correlations by utilizing a color microfilm output. In addition, gray-level pictures of statistical output, e.g., factor analysis, have been employed to aid evaluations. Examples for the data sets dysprosium-calcium, lead-copper-zinc, and equivalent uranium-uranium in water-uranium in sediment are described with respect to geologic applications, base-metal regimes, and geochemical associations

  15. Measurement network design including traveltime determinations to minimize model prediction uncertainty

    NARCIS (Netherlands)

    Janssen, G.M.C.M.; Valstar, J.R.; Zee, van der S.E.A.T.M.

    2008-01-01

    Traveltime determinations have found increasing application in the characterization of groundwater systems. No algorithms are available, however, to optimally design sampling strategies including this information type. We propose a first-order methodology to include groundwater age or tracer arrival

  16. Infection Control Practices in Dental Settings - A Review

    Directory of Open Access Journals (Sweden)

    Mohammad Mukhit Kazi

    2012-01-01

    Full Text Available In the era of HIV/ AIDS it is essential to follow the infection prevention protocols in all health care settings including dental settings. The present review article highlighted the various preventive protocols to be followed in dental settings. It includes right from the simple hand hygiene to biomedical waste segregation.

  17. Sellafield Site (including Drigg) emergency scheme manual

    International Nuclear Information System (INIS)

    1987-02-01

    This Scheme defines the organisation and procedures available should there be an accident at the Sellafield Site which results in, or may result in, the release of radioactive material, or the generation of a high radiation field, which might present a hazard to employees and/or the general public. Several categories of emergencies on the Sellafield Site are mentioned; a building emergency which is confined to one building, a Site emergency standby when the effects of a building emergency go outside that building, a Site emergency alert (District Emergency Standby) when a release of activity affects Site operations and could have serious Site effects and a District Emergency Alert when a radioactivity release may interfere with the normal activity of the General Public. A Drigg Emergency Standby situation would operate similarly at the Drigg Site. The detailed arrangements and responsibilities of appointed personnel are set out in this manual. (UK)

  18. Introduction to set theory and topology

    CERN Document Server

    Kuratowski, Kazimierz; Stark, M

    1972-01-01

    Introduction to Set Theory and Topology describes the fundamental concepts of set theory and topology as well as its applicability to analysis, geometry, and other branches of mathematics, including algebra and probability theory. Concepts such as inverse limit, lattice, ideal, filter, commutative diagram, quotient-spaces, completely regular spaces, quasicomponents, and cartesian products of topological spaces are considered. This volume consists of 21 chapters organized into two sections and begins with an introduction to set theory, with emphasis on the propositional calculus and its applica

  19. Set theoretical aspects of real analysis

    CERN Document Server

    Kharazishvili, Alexander B

    2014-01-01

    This book addresses a number of questions in real analysis and classical measure theory that are of a set-theoretic flavor. Accessible to graduate students, the beginning of the book presents introductory topics on real analysis and Lebesque measure theory. These topics highlight the boundary between fundamental concepts of measurability and non-measurability for point sets and functions. The remainder of the book deals with more specialized material on set-theoretical real analysis. Problems are included at the end of each chapter.

  20. Carrier Plus: A sensor payload for Living With a Star Space Environment Testbed (LWS/SET)

    Science.gov (United States)

    Marshall, Cheryl J.; Moss, Steven; Howard, Regan; LaBel, Kenneth A.; Grycewicz, Tom; Barth, Janet L.; Brewer, Dana

    2003-01-01

    The Defense Threat Reduction Agency (DTR4) and National Aeronautics and Space Administration (NASA) Goddard Space Flight Center are collaborating to develop the Carrier Plus sensor experiment platform as a capability of the Space Environments Testbed (SET). The Space Environment Testbed (SET) provides flight opportunities for technology experiments as part of NASA's Living With a Star (LWS) program. The Carrier Plus will provide new capability to characterize sensor technologies such as state-of-the-art visible focal plane arrays (FPAs) in a natural space radiation environment. The technical objectives include on-orbit validation of recently developed FPA technologies and performance prediction methodologies, as well as characterization of the FPA radiation response to total ionizing dose damage, displacement damage and transients. It is expected that the sensor experiment will carry 4-6 FPAs and associated radiation correlative environment monitors (CEMs) for a 2006-2007 launch. Sensor technology candidates may include n- and p-charge coupled devices (CCDs), active pixel sensors (APS), and hybrid CMOS arrays. The presentation will describe the Carrier Plus goals and objectives, as well as provide details about the architecture and design. More information on the LWS program can be found at http://lws.gsfc.nasa.gov/. Business announcements for LWS/SET and program briefings are posted at http://lws-set.gsfc.nasa.gov

  1. Re-Setting Music Education's "Default Settings"

    Science.gov (United States)

    Regelski, Thomas A.

    2013-01-01

    This paper explores the effects and problems of one highly influential default setting of the "normal style template" of music education and proposes some alternatives. These do not require abandoning all traditional templates for school music. But re-setting the default settings does depend on reconsidering the promised function of…

  2. Comparing Data Sets: Implicit Summaries of the Statistical Properties of Number Sets

    Science.gov (United States)

    Morris, Bradley J.; Masnick, Amy M.

    2015-01-01

    Comparing datasets, that is, sets of numbers in context, is a critical skill in higher order cognition. Although much is known about how people compare single numbers, little is known about how number sets are represented and compared. We investigated how subjects compared datasets that varied in their statistical properties, including ratio of…

  3. Electric Power Monthly, August 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-29

    The Electric Power Monthly (EPM) presents monthly summaries of electric utility statistics at the national, Census division, and State level. The purpose of this publication is to provide energy decisionmakers with accurate and timely information that may be used in forming various perspectives on electric issues that lie ahead. Data includes generation by energy source (coal, oil, gas, hydroelectric, and nuclear); generation by region; consumption of fossil fuels for power generation; sales of electric power, cost data; and unusual occurrences. A glossary is included.

  4. Electrochemical cell structure including an ionomeric barrier

    Science.gov (United States)

    Lambert, Timothy N.; Hibbs, Michael

    2017-06-20

    An apparatus includes an electrochemical half-cell comprising: an electrolyte, an anode; and an ionomeric barrier positioned between the electrolyte and the anode. The anode may comprise a multi-electron vanadium phosphorous alloy, such as VP.sub.x, wherein x is 1-5. The electrochemical half-cell is configured to oxidize the vanadium and phosphorous alloy to release electrons. A method of mitigating corrosion in an electrochemical cell includes disposing an ionomeric barrier in a path of electrolyte or ion flow to an anode and mitigating anion accumulation on the surface of the anode.

  5. Isolators Including Main Spring Linear Guide Systems

    Science.gov (United States)

    Goold, Ryan (Inventor); Buchele, Paul (Inventor); Hindle, Timothy (Inventor); Ruebsamen, Dale Thomas (Inventor)

    2017-01-01

    Embodiments of isolators, such as three parameter isolators, including a main spring linear guide system are provided. In one embodiment, the isolator includes first and second opposing end portions, a main spring mechanically coupled between the first and second end portions, and a linear guide system extending from the first end portion, across the main spring, and toward the second end portion. The linear guide system expands and contracts in conjunction with deflection of the main spring along the working axis, while restricting displacement and rotation of the main spring along first and second axes orthogonal to the working axis.

  6. The COG database: an updated version includes eukaryotes

    Directory of Open Access Journals (Sweden)

    Sverdlov Alexander V

    2003-09-01

    Full Text Available Abstract Background The availability of multiple, essentially complete genome sequences of prokaryotes and eukaryotes spurred both the demand and the opportunity for the construction of an evolutionary classification of genes from these genomes. Such a classification system based on orthologous relationships between genes appears to be a natural framework for comparative genomics and should facilitate both functional annotation of genomes and large-scale evolutionary studies. Results We describe here a major update of the previously developed system for delineation of Clusters of Orthologous Groups of proteins (COGs from the sequenced genomes of prokaryotes and unicellular eukaryotes and the construction of clusters of predicted orthologs for 7 eukaryotic genomes, which we named KOGs after eukaryotic orthologous groups. The COG collection currently consists of 138,458 proteins, which form 4873 COGs and comprise 75% of the 185,505 (predicted proteins encoded in 66 genomes of unicellular organisms. The eukaryotic orthologous groups (KOGs include proteins from 7 eukaryotic genomes: three animals (the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and Homo sapiens, one plant, Arabidopsis thaliana, two fungi (Saccharomyces cerevisiae and Schizosaccharomyces pombe, and the intracellular microsporidian parasite Encephalitozoon cuniculi. The current KOG set consists of 4852 clusters of orthologs, which include 59,838 proteins, or ~54% of the analyzed eukaryotic 110,655 gene products. Compared to the coverage of the prokaryotic genomes with COGs, a considerably smaller fraction of eukaryotic genes could be included into the KOGs; addition of new eukaryotic genomes is expected to result in substantial increase in the coverage of eukaryotic genomes with KOGs. Examination of the phyletic patterns of KOGs reveals a conserved core represented in all analyzed species and consisting of ~20% of the KOG set. This conserved portion of the

  7. Internet addiction neuroscientific approaches and therapeutical implications including smartphone addiction

    CERN Document Server

    Reuter, Martin

    2017-01-01

    The second edition of this successful book provides further and in-depth insight into theoretical models dealing with Internet addiction, as well as includes new therapeutical approaches. The editors also broach the emerging topic of smartphone addiction. This book combines a scholarly introduction with state-of-the-art research in the characterization of Internet addiction. It is intended for a broad audience including scientists, students and practitioners. The first part of the book contains an introduction to Internet addiction and their pathogenesis. The second part of the book is dedicated to an in-depth review of neuroscientific findings which cover studies using a variety of biological techniques including brain imaging and molecular genetics. The third part of the book focuses on therapeutic interventions for Internet addiction. The fourth part of the present book is an extension to the first edition and deals with a new emerging potential disorder related to Internet addiction – smartphone addicti...

  8. Regulation of adeno-associated virus DNA replication by the cellular TAF-I/set complex.

    Science.gov (United States)

    Pegoraro, Gianluca; Marcello, Alessandro; Myers, Michael P; Giacca, Mauro

    2006-07-01

    The Rep proteins of the adeno-associated virus (AAV) are required for viral replication in the presence of adenovirus helper functions and as yet poorly characterized cellular factors. In an attempt to identify such factors, we purified Flag-Rep68-interacting proteins from human cell lysates. Several polypeptides were identified by mass spectrometry, among which was ANP32B, a member of the acidic nuclear protein 32 family which takes part in the formation of the template-activating factor I/Set oncoprotein (TAF-I/Set) complex. The N terminus of Rep was found to specifically bind the acidic domain of ANP32B; through this interaction, Rep was also able to recruit other members of the TAF-I/Set complex, including the ANP32A protein and the histone chaperone TAF-I/Set. Further experiments revealed that silencing of ANP32A and ANP32B inhibited AAV replication, while overexpression of all of the components of the TAF-I/Set complex increased de novo AAV DNA synthesis in permissive cells. Besides being the first indication that the TAF-I/Set complex participates in wild-type AAV replication, these findings have important implications for the generation of recombinant AAV vectors since overexpression of the TAF-I/Set components was found to markedly increase viral vector production.

  9. Theory and computation of disturbance invariant sets for discrete-time linear systems

    Directory of Open Access Journals (Sweden)

    Kolmanovsky Ilya

    1998-01-01

    Full Text Available This paper considers the characterization and computation of invariant sets for discrete-time, time-invariant, linear systems with disturbance inputs whose values are confined to a specified compact set but are otherwise unknown. The emphasis is on determining maximal disturbance-invariant sets X that belong to a specified subset Γ of the state space. Such d-invariant sets have important applications in control problems where there are pointwise-in-time state constraints of the form χ ( t ∈ Γ . One purpose of the paper is to unite and extend in a rigorous way disparate results from the prior literature. In addition there are entirely new results. Specific contributions include: exploitation of the Pontryagin set difference to clarify conceptual matters and simplify mathematical developments, special properties of maximal invariant sets and conditions for their finite determination, algorithms for generating concrete representations of maximal invariant sets, practical computational questions, extension of the main results to general Lyapunov stable systems, applications of the computational techniques to the bounding of state and output response. Results on Lyapunov stable systems are applied to the implementation of a logic-based, nonlinear multimode regulator. For plants with disturbance inputs and state-control constraints it enlarges the constraint-admissible domain of attraction. Numerical examples illustrate the various theoretical and computational results.

  10. 28 CFR 20.32 - Includable offenses.

    Science.gov (United States)

    2010-07-01

    ... Exchange of Criminal History Record Information § 20.32 Includable offenses. (a) Criminal history record... vehicular manslaughter, driving under the influence of drugs or liquor, and hit and run), when unaccompanied by a § 20.32(a) offense. These exclusions may not be applicable to criminal history records...

  11. Including Students with Visual Impairments: Softball

    Science.gov (United States)

    Brian, Ali; Haegele, Justin A.

    2014-01-01

    Research has shown that while students with visual impairments are likely to be included in general physical education programs, they may not be as active as their typically developing peers. This article provides ideas for equipment modifications and game-like progressions for one popular physical education unit, softball. The purpose of these…

  12. Extending flood damage assessment methodology to include ...

    African Journals Online (AJOL)

    Optimal and sustainable flood plain management, including flood control, can only be achieved when the impacts of flood control measures are considered for both the man-made and natural environments, and the sociological aspects are fully considered. Until now, methods/models developed to determine the influences ...

  13. BIOLOGIC AND ECONOMIC EFFECTS OF INCLUDING DIFFERENT ...

    African Journals Online (AJOL)

    The biologic and economic effects of including three agro-industrial by-products as ingredients in turkey poult diets were investigated using 48 turkey poults in a completely randomised design experiment. Diets were formulated to contain the three by-products – wheat offal, rice husk and palm kernel meal, each at 20% level ...

  14. Including Children Dependent on Ventilators in School.

    Science.gov (United States)

    Levine, Jack M.

    1996-01-01

    Guidelines for including ventilator-dependent children in school are offered, based on experience with six such students at a New York State school. Guidelines stress adherence to the medical management plan, the school-family partnership, roles of the social worker and psychologist, orientation, transportation, classroom issues, and steps toward…

  15. Set Theory Correlation Free Algorithm for HRRR Target Tracking

    National Research Council Canada - National Science Library

    Blasch, Erik

    1999-01-01

    .... Recently a few fusionists including Mahler 1 and Mori 2 are using a set theory approach for a unified data fusion theory which is a correlation free paradigm 3 This paper uses the set theory approach...

  16. Geologic flow characterization using tracer techniques

    International Nuclear Information System (INIS)

    Klett, R.D.; Tyner, C.E.; Hertel, E.S. Jr.

    1981-04-01

    A new tracer flow-test system has been developed for in situ characterization of geologic formations. This report describes two sets of test equipment: one portable and one for testing in deep formations. Equations are derived for in situ detector calibration, raw data reduction, and flow logging. Data analysis techniques are presented for computing porosity and permeability in unconfined isotropic media, and porosity, permeability and fracture characteristics in media with confined or unconfined two-dimensional flow. The effects of tracer pulse spreading due to divergence, dispersion, and porous formations are also included

  17. Characterizing Water Quenching Systems with a Quench Probe

    Science.gov (United States)

    Ferguson, B. Lynn; Li, Zhichao; Freborg, Andrew M.

    2014-12-01

    Quench probes have been used effectively to characterize the quality of quenchants for many years. For this purpose, a variety of commercial probes, as well as the necessary data acquisition system for determining the time-temperature data for a set of standardized test conditions, are available for purchase. The type of information obtained from such probes provides a good basis for comparing media, characterizing general cooling capabilities, and checking media condition over time. However, these data do not adequately characterize the actual production quenching process in terms of heat transfer behavior in many cases, especially when high temperature gradients are present. Faced with the need to characterize water quenching practices, including conventional and intensive practices, a quench probe was developed. This paper describes that probe, the data collection system, the data gathered for both intensive quenching and conventional water quenching, and the heat transfer coefficients determined for these processes. Process sensitivities are investigated and highlight some intricacies of quenching.

  18. Photoactive devices including porphyrinoids with coordinating additives

    Science.gov (United States)

    Forrest, Stephen R; Zimmerman, Jeramy; Yu, Eric K; Thompson, Mark E; Trinh, Cong; Whited, Matthew; Diev, Vlacheslav

    2015-05-12

    Coordinating additives are included in porphyrinoid-based materials to promote intermolecular organization and improve one or more photoelectric characteristics of the materials. The coordinating additives are selected from fullerene compounds and organic compounds having free electron pairs. Combinations of different coordinating additives can be used to tailor the characteristic properties of such porphyrinoid-based materials, including porphyrin oligomers. Bidentate ligands are one type of coordinating additive that can form coordination bonds with a central metal ion of two different porphyrinoid compounds to promote porphyrinoid alignment and/or pi-stacking. The coordinating additives can shift the absorption spectrum of a photoactive material toward higher wavelengths, increase the external quantum efficiency of the material, or both.

  19. MOTIVATION: Goals and Goal Setting

    Science.gov (United States)

    Stratton, Richard K.

    2005-01-01

    Goal setting has great impact on a team's performance. Goals enable a team to synchronize their efforts to achieve success. In this article, the author talks about goals and goal setting. This articles complements Domain 5--Teaching and Communication (p.14) and discusses one of the benchmarks listed therein: "Teach the goal setting process and…

  20. Electric power monthly, September 1990. [Glossary included

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-17

    The purpose of this report is to provide energy decision makers with accurate and timely information that may be used in forming various perspectives on electric issues. The power plants considered include coal, petroleum, natural gas, hydroelectric, and nuclear power plants. Data are presented for power generation, fuel consumption, fuel receipts and cost, sales of electricity, and unusual occurrences at power plants. Data are compared at the national, Census division, and state levels. 4 figs., 52 tabs. (CK)

  1. Nuclear reactor shield including magnesium oxide

    International Nuclear Information System (INIS)

    Rouse, C.A.; Simnad, M.T.

    1981-01-01

    An improvement is described for nuclear reactor shielding of a type used in reactor applications involving significant amounts of fast neutron flux. The reactor shielding includes means providing structural support, neutron moderator material, neutron absorber material and other components, wherein at least a portion of the neutron moderator material is magnesium in the form of magnesium oxide either alone or in combination with other moderator materials such as graphite and iron

  2. Model for safety reports including descriptive examples

    International Nuclear Information System (INIS)

    1995-12-01

    Several safety reports will be produced in the process of planning and constructing the system for disposal of high-level radioactive waste in Sweden. The present report gives a model, with detailed examples, of how these reports should be organized and what steps they should include. In the near future safety reports will deal with the encapsulation plant and the repository. Later reports will treat operation of the handling systems and the repository

  3. Jet-calculus approach including coherence effects

    International Nuclear Information System (INIS)

    Jones, L.M.; Migneron, R.; Narayanan, K.S.S.

    1987-01-01

    We show how integrodifferential equations typical of jet calculus can be combined with an averaging procedure to obtain jet-calculus-based results including the Mueller interference graphs. Results in longitudinal-momentum fraction x for physical quantities are higher at intermediate x and lower at large x than with the conventional ''incoherent'' jet calculus. These results resemble those of Marchesini and Webber, who used a Monte Carlo approach based on the same dynamics

  4. A strategy to improve priority setting in developing countries.

    Science.gov (United States)

    Kapiriri, Lydia; Martin, Douglas K

    2007-09-01

    Because the demand for health services outstrips the available resources, priority setting is one of the most difficult issues faced by health policy makers, particularly those in developing countries. Priority setting in developing countries is fraught with uncertainty due to lack of credible information, weak priority setting institutions, and unclear priority setting processes. Efforts to improve priority setting in these contexts have focused on providing information and tools. In this paper we argue that priority setting is a value laden and political process, and although important, the available information and tools are not sufficient to address the priority setting challenges in developing countries. Additional complementary efforts are required. Hence, a strategy to improve priority setting in developing countries should also include: (i) capturing current priority setting practices, (ii) improving the legitimacy and capacity of institutions that set priorities, and (iii) developing fair priority setting processes.

  5. Panel 3 - characterization

    Energy Technology Data Exchange (ETDEWEB)

    Erck, R.A.; Erdemir, A.; Janghsing Hsieh; Lee, R.H.; Xian Zheng Pan; Deming Shu [Argonne National Lab., IL (United States); Feldman, A. [National Inst. of Standards and Technology, Gaithersburg, MD (United States); Glass, J.T. [North Carolina State Univ., Raleigh (United States); Kleimer, R. [Coors Ceramics Co., Golden, CO (United States); Lawton, E.A. [JPL/Caltech, Pasadena, CA (United States); McHargue, C.J. [Univ. of Tennessee, Knoxville (United States)

    1993-01-01

    The task of this panel was to identify and prioritize needs in the area of characterization of diamond and diamond-like-carbon (DLC) films for use in the transportation industry. Until recent advances in production of inexpensive films of diamonds and DLC, it was not feasible that these materials could be mass produced. The Characterization Panel is restricting itself to identifying needs in areas that would be most useful to manufacturers and users in producing and utilizing diamond and DLC coatings in industry. These characterization needs include in-situ monitoring during growth, relation of structure to performance, and standards and definitions.

  6. Probabilistic Characterization of Adversary Behavior in Cyber Security

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, C A; Powers, S S; Faissol, D M

    2009-10-08

    The objective of this SMS effort is to provide a probabilistic characterization of adversary behavior in cyber security. This includes both quantitative (data analysis) and qualitative (literature review) components. A set of real LLNL email data was obtained for this study, consisting of several years worth of unfiltered traffic sent to a selection of addresses at ciac.org. The email data was subjected to three interrelated analyses: a textual study of the header data and subject matter, an examination of threats present in message attachments, and a characterization of the maliciousness of embedded URLs.

  7. [Renal patient's diet: Can fish be included?].

    Science.gov (United States)

    Castro González, M I; Maafs Rodríguez, A G; Galindo Gómez, C

    2012-01-01

    Medical and nutritional treatment for renal disease, now a major public health issue, is highly complicated. Nutritional therapy must seek to retard renal dysfunction, maintain an optimal nutritional status and prevent the development of underlying pathologies. To analyze ten fish species to identify those that, because of their low phosphorus content, high biological value protein and elevated n-3 fatty acids EPA and DHA, could be included in renal patient's diet. The following fish species (Litte tunny, Red drum, Spotted eagleray, Escolar, Swordfish, Big-scale pomfret, Cortez flounder, Largemouth blackbass, Periche mojarra, Florida Pompano) were analyzed according to the AOAC and Keller techniques to determine their protein, phosphorus, sodium, potassium, cholesterol, vitamins D(3) and E, and n-3 EPA+DHA content. These results were used to calculate relations between nutrients. The protein in the analyzed species ranged from 16.5 g/100 g of fillet (Largemouth black bass) to 27.2 g/100 g (Red drum); the lowest phosphorus value was 28.6 mg/100 g (Periche mojarra) and the highest 216.3 mg/100 g (Spotted eagle ray). 80% of the fish presented > 100 mg EPA + DHA in 100 g of fillet. By its Phosphorus/gProtein ratio, Escolar and Swordfish could not be included in the renal diet; Little tunny, Escolar, Big-scale pomfret, Largemouth black-bass, Periche mojarra and Florida Pompano presented a lower Phosphorus/EPA + DHA ratio. Florida pompano is the most recommended specie for renal patients, due to its optimal nutrient relations. However, all analyzed species, except Escolar and Swordfish, could be included in renal diets.

  8. Spatial distribution of soil-transmitted helminths, including Strongyloides stercoralis, among children in Zanzibar

    Directory of Open Access Journals (Sweden)

    Stefanie Knopp

    2008-11-01

    Full Text Available A programme periodically distributing anthelminthic drugs to school-aged children for the control of soiltransmitted helminthiasis was launched in Zanzibar in the early 1990s. We investigated the spatial distribution of soiltransmitted helminth infections, including Strongyloides stercoralis, in 336 children from six districts in Unguja, Zanzibar, in 2007. One stool sample per child was examined with the Kato-Katz, Koga agar plate and Baermann methods. The point prevalence of the different helminth infections was compared to the geological characteristics of the study sites. The observed prevalences for Trichuris trichiura, Ascaris lumbricoides, hookworm and S. stercoralis were 35.5%, 12.2%, 11.9% and 2.2%, respectively, with considerable spatial heterogeneity. Whilst T. trichiura and hookworm infections were found in all six districts, no A. lumbricoides infections were recorded in the urban setting and only a low prevalence (2.2% was observed in the South district. S. stercoralis infections were found in four districts with the highest prevalence (4.0% in the West district. The prevalence of infection with any soil-transmitted helminth was highest in the North A district (69.6% and lowest in the urban setting (22.4%. A. lumbricoides, hookworm and, with the exception of the North B district, S. stercoralis infections were observed to be more prevalent in the settings north of Zanzibar Town, which are characterized by alluvial clayey soils, moist forest regions and a higher precipitation. After a decade of large-scale administration of anthelminthic drugs, the prevalence of soil-transmitted helminth infections across Unguja is still considerable. Hence, additional measures, such as improving access to adequate sanitation and clean water and continued health education, are warranted to successfully control soil-transmitted helminthiasis in Zanzibar.

  9. MOS modeling hierarchy including radiation effects

    International Nuclear Information System (INIS)

    Alexander, D.R.; Turfler, R.M.

    1975-01-01

    A hierarchy of modeling procedures has been developed for MOS transistors, circuit blocks, and integrated circuits which include the effects of total dose radiation and photocurrent response. The models were developed for use with the SCEPTRE circuit analysis program, but the techniques are suitable for other modern computer aided analysis programs. The modeling hierarchy permits the designer or analyst to select the level of modeling complexity consistent with circuit size, parametric information, and accuracy requirements. Improvements have been made in the implementation of important second order effects in the transistor MOS model, in the definition of MOS building block models, and in the development of composite terminal models for MOS integrated circuits

  10. Drug delivery device including electrolytic pump

    KAUST Repository

    Foulds, Ian G.; Buttner, Ulrich; Yi, Ying

    2016-01-01

    Systems and methods are provided for a drug delivery device and use of the device for drug delivery. In various aspects, the drug delivery device combines a “solid drug in reservoir” (SDR) system with an electrolytic pump. In various aspects an improved electrolytic pump is provided including, in particular, an improved electrolytic pump for use with a drug delivery device, for example an implantable drug delivery device. A catalytic reformer can be incorporated in a periodically pulsed electrolytic pump to provide stable pumping performance and reduced actuation cycle.

  11. Drug delivery device including electrolytic pump

    KAUST Repository

    Foulds, Ian G.

    2016-03-31

    Systems and methods are provided for a drug delivery device and use of the device for drug delivery. In various aspects, the drug delivery device combines a “solid drug in reservoir” (SDR) system with an electrolytic pump. In various aspects an improved electrolytic pump is provided including, in particular, an improved electrolytic pump for use with a drug delivery device, for example an implantable drug delivery device. A catalytic reformer can be incorporated in a periodically pulsed electrolytic pump to provide stable pumping performance and reduced actuation cycle.

  12. Using SETS to find minimal cut sets in large fault trees

    International Nuclear Information System (INIS)

    Worrell, R.B.; Stack, D.W.

    1978-01-01

    An efficient algebraic algorithm for finding the minimal cut sets for a large fault tree was defined and a new procedure which implements the algorithm was added to the Set Equation Transformation System (SETS). The algorithm includes the identification and separate processing of independent subtrees, the coalescing of consecutive gates of the same kind, the creation of additional independent subtrees, and the derivation of the fault tree stem equation in stages. The computer time required to determine the minimal cut sets using these techniques is shown to be substantially less than the computer time required to determine the minimal cut sets when these techniques are not employed. It is shown for a given example that the execution time required to determine the minimal cut sets can be reduced from 7,686 seconds to 7 seconds when all of these techniques are employed

  13. Characterization of Campylobacter phages including analysis of host range by selected Campylobacter Penner serotypes

    DEFF Research Database (Denmark)

    Hansen, Vinni; Rosenquist, Hanne; Baggesen, Dorte Lau

    2007-01-01

    range often displayed by phages. To identify the potential of phages as a Campylobacter reducing agent we needed to determine their infectivity on a panel of isolates representing the Campylobacter strains found in broilers as well as humans. Results: In this study, Campylobacter phages were isolated...... from the intestines of broilers and ducks and from abattoir sewage. Twelve phages were investigated to determine their ability to infect the Campylobacter Penner serotypes commonly present in Danish poultry and patients with campylobacteriosis. A total of 89% of the Campylobacter jejuni strains and 14...... range of 12 Danish Campylobacter phages. Due to their ability to infect the majority of the common serotypes in Denmark we suggest the phages can become an effective agent in the effort to reduce the incidence of campylobacteriosis in Denmark. This study provides the basis for future experiments...

  14. Opportunities in the Fusion Energy Sciences Program [Includes Appendix C: Topical Areas Characterization

    Energy Technology Data Exchange (ETDEWEB)

    None

    1999-06-01

    Recent years have brought dramatic advances in the scientific understanding of fusion plasmas and in the generation of fusion power in the laboratory. Today, there is little doubt that fusion energy production is feasible. The challenge is to make fusion energy practical. As a result of the advances of the last few years, there are now exciting opportunities to optimize fusion systems so that an attractive new energy source will be available when it may be needed in the middle of the next century. The risk of conflicts arising from energy shortages and supply cutoffs, as well as the risk of severe environmental impacts from existing methods of energy production, are among the reasons to pursue these opportunities.

  15. Mechanical–biological treatment: Performance and potentials. An LCA of 8 MBT plants including waste characterization

    DEFF Research Database (Denmark)

    Montejo, Cristina; Tonini, Davide; Márquez, María del Carmen

    2013-01-01

    recovery through increased automation of the selection and to prioritize biogas-electricity production from the organic fraction over direct composting. The optimal strategy for refuse derived fuel (RDF) management depends upon the environmental compartment to be prioritized and the type of marginal...... of the MBT plants. These widely differed in type of biological treatment and recovery efficiencies. The results indicated that the performance is strongly connected with energy and materials recovery efficiency. The recommendation for upgrading and/or commissioning of future plants is to optimize materials...... electricity source in the system. It was estimated that, overall, up to ca. 180—190 kt CO2-eq. y−1 may be saved by optimizing the MBT plants under assessment....

  16. Accurate spectroscopic characterization of ethyl mercaptan and dimethyl sulfide isotopologues: a route toward their astrophysical detection

    Energy Technology Data Exchange (ETDEWEB)

    Puzzarini, C. [Dipartimento di Chimica, " Giacomo Ciamician," Università diBologna, Via F. Selmi 2, I-40126 Bologna (Italy); Senent, M. L. [Departamento de Química y Física Teóricas, Institsuto de Estructura de la Materia, IEM-C.S.I.C., Serrano 121, Madrid E-28006 (Spain); Domínguez-Gómez, R. [Doctora Vinculada IEM-CSIC, Departamento de Ingeniería Civil, Cátedra de Química, E.U.I.T. Obras Públicas, Universidad Politécnica de Madrid (Spain); Carvajal, M. [Departamento de Física Aplicada, Facultad de Ciencias Experimentales, Unidad Asociada IEM-CSIC-U.Huelva, Universidad de Huelva, E-21071 Huelva (Spain); Hochlaf, M. [Université Paris-Est, Laboratoire de Modélisation et Simulation Multi Echelle, MSME UMR 8208 CNRS, 5 boulevard Descartes, F-77454 Marne-la-Vallée (France); Al-Mogren, M. Mogren, E-mail: cristina.puzzarini@unibo.it, E-mail: senent@iem.cfmac.csic.es, E-mail: rosa.dominguez@upm.es, E-mail: miguel.carvajal@dfa.uhu.es, E-mail: majdi.hochlaf@u-pem.fr, E-mail: mmogren@ksu.edu.sa [Chemistry Department, Faculty of Science, King Saud University, PO Box 2455, Riyadh 11451 (Saudi Arabia)

    2014-11-20

    Using state-of-the-art computational methodologies, we predict a set of reliable rotational and torsional parameters for ethyl mercaptan and dimethyl sulfide monosubstituted isotopologues. This includes rotational, quartic, and sextic centrifugal-distortion constants, torsional levels, and torsional splittings. The accuracy of the present data was assessed from a comparison to the available experimental data. Generally, our computed parameters should help in the characterization and the identification of these organo-sulfur molecules in laboratory settings and in the interstellar medium.

  17. Energy principle with included boundary conditions

    International Nuclear Information System (INIS)

    Lehnert, B.

    1994-01-01

    Earlier comments by the author on the limitations of the classical form of the extended energy principle are supported by a complementary analysis on the potential energy change arising from free-boundary displacements of a magnetically confined plasma. In the final formulation of the extended principle, restricted displacements, satisfying pressure continuity by means of plasma volume currents in a thin boundary layer, are replaced by unrestricted (arbitrary) displacements which can give rise to induced surface currents. It is found that these currents contribute to the change in potential energy, and that their contribution is not taken into account by such a formulation. A general expression is further given for surface currents induced by arbitrary displacements. The expression is used to reformulate the energy principle for the class of displacements which satisfy all necessary boundary conditions, including that of the pressure balance. This makes a minimization procedure of the potential energy possible, for the class of all physically relevant test functions which include the constraints imposed by the boundary conditions. Such a procedure is also consistent with a corresponding variational calculus. (Author)

  18. Addressing Stillbirth in India Must Include Men.

    Science.gov (United States)

    Roberts, Lisa; Montgomery, Susanne; Ganesh, Gayatri; Kaur, Harinder Pal; Singh, Ratan

    2017-07-01

    Millennium Development Goal 4, to reduce child mortality, can only be achieved by reducing stillbirths globally. A confluence of medical and sociocultural factors contribute to the high stillbirth rates in India. The psychosocial aftermath of stillbirth is a well-documented public health problem, though less is known of the experience for men, particularly outside of the Western context. Therefore, men's perceptions and knowledge regarding reproductive health, as well as maternal-child health are important. Key informant interviews (n = 5) were analyzed and 28 structured interviews were conducted using a survey based on qualitative themes. Qualitative themes included men's dual burden and right to medical and reproductive decision making power. Wives were discouraged from expressing grief and pushed to conceive again. If not successful, particularly if a son was not conceived, a second wife was considered a solution. Quantitative data revealed that men with a history of stillbirths had greater anxiety and depression, perceived less social support, but had more egalitarian views towards women than men without stillbirth experience. At the same time fathers of stillbirths were more likely to be emotionally or physically abusive. Predictors of mental health, attitudes towards women, and perceived support are discussed. Patriarchal societal values, son preference, deficient women's autonomy, and sex-selective abortion perpetuate the risk for future poor infant outcomes, including stillbirth, and compounds the already higher risk of stillbirth for males. Grief interventions should explore and take into account men's perceptions, attitudes, and behaviors towards reproductive decision making.

  19. Report on the remedial investigation of Bear Creek Valley at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Volume 2: Appendix A -- Waste sites, source terms, and waste inventory report; Appendix B -- Description of the field activities and report database; Appendix C -- Characterization of hydrogeologic setting report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    This Remedial Investigation (RI) Report characterizes the nature and extent of contamination, evaluates the fate and transport of contaminants, and assesses risk to human health and the environment resulting from waste disposal and other US Department of Energy (DOE) operations in Bear Creek Valley (BCV). BCV, which is located within the DOE Oak Ridge Reservation (ORR) encompasses multiple waste units containing hazardous and radioactive wastes arising from operations at the adjacent Oak Ridge Y-12 Plant. The primary waste units discussed in this RI Report are the S-3 Site, Oil Landfarm (OLF), Boneyard/Burnyard (BYBY), Sanitary Landfill 1 (SL 1), and Bear Creek Burial Grounds (BCBG). These waste units, plus the contaminated media resulting from environmental transport of the wastes from these units, are the subject of this RI. This BCV RI Report represents the first major step in the decision-making process for the BCV watershed. The RI results, in concert with the follow-on FS will form the basis for the Proposed Plan and Record of Decision for all BCV sites. This comprehensive decision document process will meet the objectives of the watershed approach for BCV. Appendix A includes descriptions of waste areas and estimates of the current compositions of the wastes. Appendix B contains an extensive database of environmental data for the Bear Creek Valley Characterization Area. Information is also presented about the number and location of samples collected, the analytes examined, and the extent of data validation. Appendix C describes the hydrogeologic conceptual model for Bear Creek Valley. This model is one of the principal components of the conceptual site models for contaminant transport in BCV.

  20. Report on the remedial investigation of Bear Creek Valley at the Oak Ridge Y-12 Plant, Oak Ridge, Tennessee. Volume 2: Appendix A - Waste sites, source terms, and waste inventory report; Appendix B - Description of the field activities and report database; Appendix C - Characterization of hydrogeologic setting report

    International Nuclear Information System (INIS)

    1996-01-01

    This Remedial Investigation (RI) Report characterizes the nature and extent of contamination, evaluates the fate and transport of contaminants, and assesses risk to human health and the environment resulting from waste disposal and other US Department of Energy (DOE) operations in Bear Creek Valley (BCV). BCV, which is located within the DOE Oak Ridge Reservation (ORR) encompasses multiple waste units containing hazardous and radioactive wastes arising from operations at the adjacent Oak Ridge Y-12 Plant. The primary waste units discussed in this RI Report are the S-3 Site, Oil Landfarm (OLF), Boneyard/Burnyard (BYBY), Sanitary Landfill 1 (SL 1), and Bear Creek Burial Grounds (BCBG). These waste units, plus the contaminated media resulting from environmental transport of the wastes from these units, are the subject of this RI. This BCV RI Report represents the first major step in the decision-making process for the BCV watershed. The RI results, in concert with the follow-on FS will form the basis for the Proposed Plan and Record of Decision for all BCV sites. This comprehensive decision document process will meet the objectives of the watershed approach for BCV. Appendix A includes descriptions of waste areas and estimates of the current compositions of the wastes. Appendix B contains an extensive database of environmental data for the Bear Creek Valley Characterization Area. Information is also presented about the number and location of samples collected, the analytes examined, and the extent of data validation. Appendix C describes the hydrogeologic conceptual model for Bear Creek Valley. This model is one of the principal components of the conceptual site models for contaminant transport in BCV

  1. Visual CRO display of pulse height distribution including discriminator setting for a single channel X-ray analyser

    International Nuclear Information System (INIS)

    Shaw, S.E.

    1979-01-01

    An outline for a simple pulse spectroscope which attaches to a standard laboratory CRO is presented. The peak amplitude voltage of each pulse from the linear amplifier of a single channel X-ray analyser is stored for the duration of one oscilloscope trace. For each amplifier pulse, input from the discriminator is tested and if these is coincidence of pulses the oscilloscope beam is blanked for approximately the first 2 cm of its traverse across the screen. Repetition of pulses forms a pulse height distribution with a rectangular dark area marking the position of the discriminator window. (author)

  2. Including gauge corrections to thermal leptogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Huetig, Janine

    2013-05-17

    This thesis provides the first approach of a systematic inclusion of gauge corrections to leading order to the ansatz of thermal leptogenesis. We have derived a complete expression for the integrated lepton number matrix including all resummations needed. For this purpose, a new class of diagram has been invented, namely the cylindrical diagram, which allows diverse investigations into the topic of leptogenesis such as the case of resonant leptogenesis. After a brief introduction of the topic of the baryon asymmetry in the universe and a discussion of its most promising solutions as well as their advantages and disadvantages, we have presented our framework of thermal leptogenesis. An effective model was described as well as the associated Feynman rules. The basis for using nonequilibrium quantum field theory has been built in chapter 3. At first, the main definitions have been presented for equilibrium thermal field theory, afterwards we have discussed the Kadanoff-Baym equations for systems out of equilibrium using the example of the Majorana neutrino. The equations have also been solved in the context of leptogenesis in chapter 4. Since gauge corrections play a crucial role throughout this thesis, we have also repeated the naive ansatz by replacing the free equilibrium propagator by propagators including thermal damping rates due to the Standard Model damping widths for lepton and Higgs fields. It is shown that this leads to a comparable result to the solutions of the Boltzmann equations for thermal leptogenesis. Thus it becomes obvious that Standard Model corrections are not negligible for thermal leptogenesis and therefore need to be included systematically from first principles. In order to achieve this we have started discussing the calculation of ladder rung diagrams for Majorana neutrinos using the HTL and the CTL approach in chapter 5. All gauge corrections are included in this framework and thus it has become the basis for the following considerations

  3. Including gauge corrections to thermal leptogenesis

    International Nuclear Information System (INIS)

    Huetig, Janine

    2013-01-01

    This thesis provides the first approach of a systematic inclusion of gauge corrections to leading order to the ansatz of thermal leptogenesis. We have derived a complete expression for the integrated lepton number matrix including all resummations needed. For this purpose, a new class of diagram has been invented, namely the cylindrical diagram, which allows diverse investigations into the topic of leptogenesis such as the case of resonant leptogenesis. After a brief introduction of the topic of the baryon asymmetry in the universe and a discussion of its most promising solutions as well as their advantages and disadvantages, we have presented our framework of thermal leptogenesis. An effective model was described as well as the associated Feynman rules. The basis for using nonequilibrium quantum field theory has been built in chapter 3. At first, the main definitions have been presented for equilibrium thermal field theory, afterwards we have discussed the Kadanoff-Baym equations for systems out of equilibrium using the example of the Majorana neutrino. The equations have also been solved in the context of leptogenesis in chapter 4. Since gauge corrections play a crucial role throughout this thesis, we have also repeated the naive ansatz by replacing the free equilibrium propagator by propagators including thermal damping rates due to the Standard Model damping widths for lepton and Higgs fields. It is shown that this leads to a comparable result to the solutions of the Boltzmann equations for thermal leptogenesis. Thus it becomes obvious that Standard Model corrections are not negligible for thermal leptogenesis and therefore need to be included systematically from first principles. In order to achieve this we have started discussing the calculation of ladder rung diagrams for Majorana neutrinos using the HTL and the CTL approach in chapter 5. All gauge corrections are included in this framework and thus it has become the basis for the following considerations

  4. Default settings of computerized physician order entry system order sets drive ordering habits.

    Science.gov (United States)

    Olson, Jordan; Hollenbeak, Christopher; Donaldson, Keri; Abendroth, Thomas; Castellani, William

    2015-01-01

    laboratory tests. Careful consideration by all stakeholders, including clinicians and pathologists, should be obtained when establishing default settings in order sets.

  5. The surgery of peripheral nerves (including tumors)

    DEFF Research Database (Denmark)

    Fugleholm, Kåre

    2013-01-01

    Surgical pathology of the peripheral nervous system includes traumatic injury, entrapment syndromes, and tumors. The recent significant advances in the understanding of the pathophysiology and cellular biology of peripheral nerve degeneration and regeneration has yet to be translated into improved...... surgical techniques and better outcome after peripheral nerve injury. Decision making in peripheral nerve surgery continues to be a complex challenge, where the mechanism of injury, repeated clinical evaluation, neuroradiological and neurophysiological examination, and detailed knowledge of the peripheral...... nervous system response to injury are prerequisite to obtain the best possible outcome. Surgery continues to be the primary treatment modality for peripheral nerve tumors and advances in adjuvant oncological treatment has improved outcome after malignant peripheral nerve tumors. The present chapter...

  6. AMS at the ANU including biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Fifield, L K; Allan, G L; Cresswell, R G; Ophel, T R [Australian National Univ., Canberra, ACT (Australia); King, S J; Day, J P [Manchester Univ. (United Kingdom). Dept. of Chemistry

    1994-12-31

    An extensive accelerator mass spectrometry program has been conducted on the 14UD accelerator at the Australian National University since 1986. In the two years since the previous conference, the research program has expanded significantly to include biomedical applications of {sup 26}Al and studies of landform evolution using isotopes produced in situ in surface rocks by cosmic ray bombardment. The system is now used for the measurement of {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36}Cl, {sup 59}Ni and {sup 129}I, and research is being undertaken in hydrology, environmental geochemistry, archaeology and biomedicine. On the technical side, a new test system has permitted the successful off-line development of a high-intensity ion source. A new injection line to the 14UD has been established and the new source is now in position and providing beams to the accelerator. 4 refs.

  7. AMS at the ANU including biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Fifield, L.K.; Allan, G.L.; Cresswell, R.G.; Ophel, T.R. [Australian National Univ., Canberra, ACT (Australia); King, S.J.; Day, J.P. [Manchester Univ. (United Kingdom). Dept. of Chemistry

    1993-12-31

    An extensive accelerator mass spectrometry program has been conducted on the 14UD accelerator at the Australian National University since 1986. In the two years since the previous conference, the research program has expanded significantly to include biomedical applications of {sup 26}Al and studies of landform evolution using isotopes produced in situ in surface rocks by cosmic ray bombardment. The system is now used for the measurement of {sup 10}Be, {sup 14}C, {sup 26}Al, {sup 36}Cl, {sup 59}Ni and {sup 129}I, and research is being undertaken in hydrology, environmental geochemistry, archaeology and biomedicine. On the technical side, a new test system has permitted the successful off-line development of a high-intensity ion source. A new injection line to the 14UD has been established and the new source is now in position and providing beams to the accelerator. 4 refs.

  8. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course pr...

  9. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of the "LabView Basic I" and "LabView Intermediate II" courses have recently been changed to include, respectively, an introduction to and expert training in the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to developing expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepares participants to develop test and measurement, da...

  10. CERN Technical Training: LABVIEW courses include RADE

    CERN Multimedia

    HR Department

    2009-01-01

    The contents of "LabView Basic I" and "LabView Intermediate II" trainings have been recently changed to include, respectively, an introduction and an expert training on the Rapid Application Development Environment (RADE). RADE is a LabView-based application developed at CERN to integrate LabView in the accelerator and experiment control infrastructure. It is a suitable solution to develop expert tools, machine development analysis and independent test facilities. The course names have also been changed to "LabVIEW Basics I with RADE Introduction" and "LabVIEW Intermediate II with Advanced RADE Application". " LabVIEW Basics I with RADE Introduction" is designed for: Users preparing to develop applications using LabVIEW, or NI Developer Suite; users and technical managers evaluating LabVIEW or NI Developer Suite in purchasing decisions; users pursuing the Certified LabVIEW Developer certification. The course prepare...

  11. Critical point anomalies include expansion shock waves

    Energy Technology Data Exchange (ETDEWEB)

    Nannan, N. R., E-mail: ryan.nannan@uvs.edu [Mechanical Engineering Discipline, Anton de Kom University of Suriname, Leysweg 86, PO Box 9212, Paramaribo, Suriname and Process and Energy Department, Delft University of Technology, Leeghwaterstraat 44, 2628 CA Delft (Netherlands); Guardone, A., E-mail: alberto.guardone@polimi.it [Department of Aerospace Science and Technology, Politecnico di Milano, Via La Masa 34, 20156 Milano (Italy); Colonna, P., E-mail: p.colonna@tudelft.nl [Propulsion and Power, Delft University of Technology, Kluyverweg 1, 2629 HS Delft (Netherlands)

    2014-02-15

    From first-principle fluid dynamics, complemented by a rigorous state equation accounting for critical anomalies, we discovered that expansion shock waves may occur in the vicinity of the liquid-vapor critical point in the two-phase region. Due to universality of near-critical thermodynamics, the result is valid for any common pure fluid in which molecular interactions are only short-range, namely, for so-called 3-dimensional Ising-like systems, and under the assumption of thermodynamic equilibrium. In addition to rarefaction shock waves, diverse non-classical effects are admissible, including composite compressive shock-fan-shock waves, due to the change of sign of the fundamental derivative of gasdynamics.

  12. CLIC expands to include the Southern Hemisphere

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    Australia has recently joined the CLIC collaboration: the enlargement will bring new expertise and resources to the project, and is especially welcome in the wake of CERN budget redistributions following the recent adoption of the Medium Term Plan.   The countries involved in CLIC collaboration With the signing of a Memorandum of Understanding on 26 August 2010, the ACAS network (Australian Collaboration for Accelerator Science) became the 40th member of in the multilateral CLIC collaboration making Australia the 22nd country to join the collaboration. “The new MoU was signed by the ACAS network, which includes the Australian Synchrotron and the University of Melbourne”, explains Jean-Pierre Delahaye, CLIC Study Leader. “Thanks to their expertise, the Australian institutes will contribute greatly to the CLIC damping rings and the two-beam test modules." Institutes from any country wishing to join the CLIC collaboration are invited to assume responsibility o...

  13. Should Broca's area include Brodmann area 47?

    Science.gov (United States)

    Ardila, Alfredo; Bernal, Byron; Rosselli, Monica

    2017-02-01

    Understanding brain organization of speech production has been a principal goal of neuroscience. Historically, brain speech production has been associated with so-called Broca’s area (Brodmann area –BA- 44 and 45), however, modern neuroimaging developments suggest speech production is associated with networks rather than with areas. The purpose of this paper was to analyze the connectivity of BA47 ( pars orbitalis) in relation to language . A meta-analysis was conducted to assess the language network in which BA47 is involved. The Brainmap database was used. Twenty papers corresponding to 29 experimental conditions with a total of 373 subjects were included. Our results suggest that BA47 participates in a “frontal language production system” (or extended Broca’s system). The BA47  connectivity found is also concordant with a minor role in language semantics. BA47 plays a central role in the language production system.

  14. Musculoskeletal ultrasound including definitions for ultrasonographic pathology

    DEFF Research Database (Denmark)

    Wakefield, RJ; Balint, PV; Szkudlarek, Marcin

    2005-01-01

    Ultrasound (US) has great potential as an outcome in rheumatoid arthritis trials for detecting bone erosions, synovitis, tendon disease, and enthesopathy. It has a number of distinct advantages over magnetic resonance imaging, including good patient tolerability and ability to scan multiple joints...... in a short period of time. However, there are scarce data regarding its validity, reproducibility, and responsiveness to change, making interpretation and comparison of studies difficult. In particular, there are limited data describing standardized scanning methodology and standardized definitions of US...... pathologies. This article presents the first report from the OMERACT ultrasound special interest group, which has compared US against the criteria of the OMERACT filter. Also proposed for the first time are consensus US definitions for common pathological lesions seen in patients with inflammatory arthritis....

  15. Grand unified models including extra Z bosons

    International Nuclear Information System (INIS)

    Li Tiezhong

    1989-01-01

    The grand unified theories (GUT) of the simple Lie groups including extra Z bosons are discussed. Under authors's hypothesis there are only SU 5+m SO 6+4n and E 6 groups. The general discussion of SU 5+m is given, then the SU 6 and SU 7 are considered. In SU 6 the 15+6 * +6 * fermion representations are used, which are not same as others in fermion content, Yukawa coupling and broken scales. A conception of clans of particles, which are not families, is suggested. These clans consist of extra Z bosons and the corresponding fermions of the scale. The all of fermions in the clans are down quarks except for the standard model which consists of Z bosons and 15 fermions, therefore, the spectrum of the hadrons which are composed of these down quarks are different from hadrons at present

  16. Including climate change in energy investment decisions

    International Nuclear Information System (INIS)

    Ybema, J.R.; Boonekamp, P.G.M.; Smit, J.T.J.

    1995-08-01

    To properly take climate change into account in the analysis of energy investment decisions, it is required to apply decision analysis methods that are capable of considering the specific characteristics of climate change (large uncertainties, long term horizon). Such decision analysis methods do exist. They can explicitly include evolving uncertainties, multi-stage decisions, cumulative effects and risk averse attitudes. Various methods are considered in this report and two of these methods have been selected: hedging calculations and sensitivity analysis. These methods are applied to illustrative examples, and its limitations are discussed. The examples are (1a) space heating and hot water for new houses from a private investor perspective and (1b) as example (1a) but from a government perspective, (2) electricity production with an integrated coal gasification combined cycle (ICGCC) with or without CO 2 removal, and (3) national energy strategy to hedge for climate change. 9 figs., 21 tabs., 42 refs., 1 appendix

  17. Education Program on Fossil Resources Including Coal

    Science.gov (United States)

    Usami, Masahiro

    Fossil fuels including coal play a key role as crucial energies in contributing to economic development in Asia. On the other hand, its limited quantity and the environmental problems causing from its usage have become a serious global issue and a countermeasure to solve such problems is very much demanded. Along with the pursuit of sustainable development, environmentally-friendly use of highly efficient fossil resources should be therefore, accompanied. Kyushu-university‧s sophisticated research through long years of accumulated experience on the fossil resources and environmental sectors together with the advanced large-scale commercial and empirical equipments will enable us to foster cooperative research and provide internship program for the future researchers. Then, this program is executed as a consignment business from the Ministry of Economy, Trade and Industry from 2007 fiscal year to 2009 fiscal year. The lecture that uses the textbooks developed by this program is scheduled to be started a course in fiscal year 2010.

  18. A characterization of graphs with disjoint dominating and total ...

    African Journals Online (AJOL)

    A dominating set of a graph is a set of vertices such that every vertex not in the set is adjacent to a vertex in the set, while a total dominating set of a graph is a set of vertices such that every vertex is adjacent to a vertex in the set. In this paper, we provide a constructive characterization of graphs whose vertex set can be ...

  19. Image characterization metrics for muon tomography

    Science.gov (United States)

    Luo, Weidong; Lehovich, Andre; Anashkin, Edward; Bai, Chuanyong; Kindem, Joel; Sossong, Michael; Steiger, Matt

    2014-05-01

    Muon tomography uses naturally occurring cosmic rays to detect nuclear threats in containers. Currently there are no systematic image characterization metrics for muon tomography. We propose a set of image characterization methods to quantify the imaging performance of muon tomography. These methods include tests of spatial resolution, uniformity, contrast, signal to noise ratio (SNR) and vertical smearing. Simulated phantom data and analysis methods were developed to evaluate metric applicability. Spatial resolution was determined as the FWHM of the point spread functions in X, Y and Z axis for 2.5cm tungsten cubes. Uniformity was measured by drawing a volume of interest (VOI) within a large water phantom and defined as the standard deviation of voxel values divided by the mean voxel value. Contrast was defined as the peak signals of a set of tungsten cubes divided by the mean voxel value of the water background. SNR was defined as the peak signals of cubes divided by the standard deviation (noise) of the water background. Vertical smearing, i.e. vertical thickness blurring along the zenith axis for a set of 2 cm thick tungsten plates, was defined as the FWHM of vertical spread function for the plate. These image metrics provided a useful tool to quantify the basic imaging properties for muon tomography.

  20. Two sets of twins with selective mutism: neuropsychological findings.

    Science.gov (United States)

    Gray, Robert M; Jordan, Catherine M; Ziegler, Richard S; Livingston, Ronald B

    2002-03-01

    Neuropsychological data are reviewed from two sets of dizygotic twins presenting with selective mutism characterized by situation specific anxiety, extreme passive behavior, lack of responsivity, lack of peer interaction, and a chronic course of selective mutism. Both sets of twins had a history of prematurity and delayed speech development. One set of twins presented with normal intelligence and normal receptive language skills but with expressive language and oral motor sequencing difficulties. The second set of twins presented with Verbal IQ deficits and significant receptive and expressive language deficits. A summary of current conceptualizations regarding etiology and treatment of selective mutism is provided.

  1. Analysis of Smart Composite Structures Including Debonding

    Science.gov (United States)

    Chattopadhyay, Aditi; Seeley, Charles E.

    1997-01-01

    Smart composite structures with distributed sensors and actuators have the capability to actively respond to a changing environment while offering significant weight savings and additional passive controllability through ply tailoring. Piezoelectric sensing and actuation of composite laminates is the most promising concept due to the static and dynamic control capabilities. Essential to the implementation of these smart composites are the development of accurate and efficient modeling techniques and experimental validation. This research addresses each of these important topics. A refined higher order theory is developed to model composite structures with surface bonded or embedded piezoelectric transducers. These transducers are used as both sensors and actuators for closed loop control. The theory accurately captures the transverse shear deformation through the thickness of the smart composite laminate while satisfying stress free boundary conditions on the free surfaces. The theory is extended to include the effect of debonding at the actuator-laminate interface. The developed analytical model is implemented using the finite element method utilizing an induced strain approach for computational efficiency. This allows general laminate geometries and boundary conditions to be analyzed. The state space control equations are developed to allow flexibility in the design of the control system. Circuit concepts are also discussed. Static and dynamic results of smart composite structures, obtained using the higher order theory, are correlated with available analytical data. Comparisons, including debonded laminates, are also made with a general purpose finite element code and available experimental data. Overall, very good agreement is observed. Convergence of the finite element implementation of the higher order theory is shown with exact solutions. Additional results demonstrate the utility of the developed theory to study piezoelectric actuation of composite

  2. Diarrhea Management Training in Early Childhood Settings.

    Science.gov (United States)

    Winnail, Scott D.; Artz, Lynn M.; Geiger, Brian F.; Petri, Cynthia J.; Bailey, Rebecca; Mason, J.W.

    2001-01-01

    Addresses the health of young children and how to safely and effectively care for children with diarrhea in the home and in early child care settings. Discusses specific intervention and program activities, including specially designed materials for mixing homemade oral rehydration usage. (Author/SD)

  3. The "Set Map" Method of Navigation.

    Science.gov (United States)

    Tippett, Julian

    1998-01-01

    Explains the "set map" method of using the baseplate compass to solve walkers' navigational needs as opposed to the 1-2-3 method for taking a bearing. The map, with the compass permanently clipped to it, is rotated to the position in which its features have the same orientation as their counterparts on the ground. Includes directions and…

  4. Healthcare priority setting in Kenya

    DEFF Research Database (Denmark)

    Bukachi, Salome A.; Onyango-Ouma, Washington; Siso, Jared Maaka

    2014-01-01

    In resource-poor settings, the accountability for reasonableness (A4R) has been identified as an important advance in priority setting that helps to operationalize fair priority setting in specific contexts. The four conditions of A4R are backed by theory, not evidence, that conformance with them...... improves the priority setting decisions. This paper describes the healthcare priority setting processes in Malindi district, Kenya, prior to the implementation of A4R in 2008 and evaluates the process for its conformance with the conditions for A4R. In-depth interviews and focus group discussions with key...... players in the Malindi district health system and a review of key policy documents and national guidelines show that the priority setting process in the district relies heavily on guidelines from the national level, making it more of a vertical, top-down orientation. Multilateral and donor agencies...

  5. Social settings and addiction relapse.

    Science.gov (United States)

    Walton, M A; Reischl, T M; Ramanthan, C S

    1995-01-01

    Despite addiction theorists' acknowledgment of the impact of environmental factors on relapse, researchers have not adequately investigated these influences. Ninety-six substance users provided data regarding their perceived risk for relapse, exposure to substances, and involvement in reinforcing activities. These three setting attributes were assessed in their home, work, and community settings. Reuse was assessed 3 months later. When controlling for confounding variables, aspects of the home settings significantly distinguished abstainers from reusers; perceived risk for relapse was the strongest predictor of reuse. Exposure to substances and involvement in reinforcing activities were not robust reuse indicators. The work and community settings were not significant determinants of reuse. These findings offer some initial support for the utility of examining social settings to better understand addiction relapse and recovery. Identification of setting-based relapse determinants provides concrete targets for relapse prevention interventions.

  6. Zγ production at NNLO including anomalous couplings

    Science.gov (United States)

    Campbell, John M.; Neumann, Tobias; Williams, Ciaran

    2017-11-01

    In this paper we present a next-to-next-to-leading order (NNLO) QCD calculation of the processes pp → l + l -γ and pp\\to ν \\overline{ν}γ that we have implemented in MCFM. Our calculation includes QCD corrections at NNLO both for the Standard Model (SM) and additionally in the presence of Zγγ and ZZγ anomalous couplings. We compare our implementation, obtained using the jettiness slicing approach, with a previous SM calculation and find broad agreement. Focusing on the sensitivity of our results to the slicing parameter, we show that using our setup we are able to compute NNLO cross sections with numerical uncertainties of about 0.1%, which is small compared to residual scale uncertainties of a few percent. We study potential improvements using two different jettiness definitions and the inclusion of power corrections. At √{s}=13 TeV we present phenomenological results and consider Zγ as a background to H → Zγ production. We find that, with typical cuts, the inclusion of NNLO corrections represents a small effect and loosens the extraction of limits on anomalous couplings by about 10%.

  7. Alternating phase focussing including space charge

    International Nuclear Information System (INIS)

    Cheng, W.H.; Gluckstern, R.L.

    1992-01-01

    Longitudinal stability can be obtained in a non-relativistic drift tube accelerator by traversing each gap as the rf accelerating field rises. However, the rising accelerating field leads to a transverse defocusing force which is usually overcome by magnetic focussing inside the drift tubes. The radio frequency quadrupole is one way of providing simultaneous longitudinal and transverse focusing without the use of magnets. One can also avoid the use of magnets by traversing alternate gaps between drift tubes as the field is rising and falling, thus providing an alternation of focussing and defocusing forces in both the longitudinal and transverse directions. The stable longitudinal phase space area is quite small, but recent efforts suggest that alternating phase focussing (APF) may permit low velocity acceleration of currents in the 100-300 ma range. This paper presents a study of the parameter space and a test of crude analytic predictions by adapting the code PARMILA, which includes space charge, to APF. 6 refs., 3 figs

  8. Probabilistic production simulation including CHP plants

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, H.V.; Palsson, H.; Ravn, H.F.

    1997-04-01

    A probabilistic production simulation method is presented for an energy system containing combined heat and power plants. The method permits incorporation of stochastic failures (forced outages) of the plants and is well suited for analysis of the dimensioning of the system, that is, for finding the appropriate types and capacities of production plants in relation to expansion planning. The method is in the tradition of similar approaches for the analysis of power systems, based on the load duration curve. The present method extends on this by considering a two-dimensional load duration curve where the two dimensions represent heat and power. The method permits the analysis of a combined heat and power system which includes all the basic relevant types of plants, viz., condensing plants, back pressure plants, extraction plants and heat plants. The focus of the method is on the situation where the heat side has priority. This implies that on the power side there may be imbalances between demand and production. The method permits quantification of the expected power overflow, the expected unserviced power demand, and the expected unserviced heat demand. It is shown that a discretization method as well as double Fourier series may be applied in algorithms based on the method. (au) 1 tab., 28 ills., 21 refs.

  9. Langevin simulations of QCD, including fermions

    International Nuclear Information System (INIS)

    Kronfeld, A.S.

    1986-02-01

    We encounter critical slow down in updating when xi/a -> infinite and in matrix inversion (needed to include fermions) when msub(q)a -> 0. A simulation that purports to solve QCD numerically will encounter these limits, so to face the challenge in the title of this workshop, we must cure the disease of critical slow down. Physically, this critical slow down is due to the reluctance of changes at short distances to propagate to large distances. Numerically, the stability of an algorithm at short wavelengths requires a (moderately) small step size; critical slow down occurs when the effective long wavelength step size becomes tiny. The remedy for this disease is an algorithm that propagates signals quickly throughout the system; i.e. one whose effective step size is not reduced for the long wavelength conponents of the fields. (Here the effective ''step size'' is essentially an inverse decorrelation time.) To do so one must resolve various wavelengths of the system and modify the dynamics (in CPU time) of the simulation so that all modes evolve at roughly the same rate. This can be achieved by introducing Fourier transforms. I show how to implement Fourier acceleration for Langevin updating and for conjugate gradient matrix inversion. The crucial feature of these algorithms that lends them to Fourier acceleration is that they update the lattice globally; hence the Fourier transforms are computed once per sweep rather than once per hit. (orig./HSI)

  10. Hierarchical Sets: Analyzing Pangenome Structure through Scalable Set Visualizations

    DEFF Research Database (Denmark)

    Pedersen, Thomas Lin

    2017-01-01

    of hierarchical sets by applying it to a pangenome based on 113 Escherichia and Shigella genomes and find it provides a powerful addition to pangenome analysis. The described clustering algorithm and visualizations are implemented in the hierarchicalSets R package available from CRAN (https...

  11. Fuzzy reasoning on Horn Set

    International Nuclear Information System (INIS)

    Liu, X.; Fang, K.

    1986-01-01

    A theoretical study in fuzzy reasoning on Horn Set is presented in this paper. The authors first introduce the concepts of λ-Horn Set of clauses and λ-Input Half Lock deduction. They then use the λ-resolution method to discuss fuzzy reasoning on λ-Horn set of clauses. It is proved that the proposed λ-Input Half Lock resolution method is complete with the rules in certain format

  12. APPLICATION OF GOAL SETTING THEORY

    OpenAIRE

    Yurtkoru, E. Serra; Bozkurt, Tulay; Bekta, Fatos; Ahmed, Mahir Jibril; Kola, Vehap

    2017-01-01

    The purpose of this study is to test the goal theorymodel originally developed by Locke and Latham in organizational setting inTurkey, and explain its influence on job satisfaction and affective commitment.Also mediating role of task specific strategy and moderating role ofselfefficacy are examined. Locke and Latham’s goal setting measure is adaptedto Turkish. Survey method is employed to collect data from 222 respondents fromautomotive industry. Goal setting dimensions predicted affective co...

  13. Algorithms over partially ordered sets

    DEFF Research Database (Denmark)

    Baer, Robert M.; Østerby, Ole

    1969-01-01

    in partially ordered sets, answer the combinatorial question of how many maximal chains might exist in a partially ordered set withn elements, and we give an algorithm for enumerating all maximal chains. We give (in § 3) algorithms which decide whether a partially ordered set is a (lower or upper) semi......-lattice, and whether a lattice has distributive, modular, and Boolean properties. Finally (in § 4) we give Algol realizations of the various algorithms....

  14. Mapping topographic structure in white matter pathways with level set trees.

    Directory of Open Access Journals (Sweden)

    Brian P Kent

    Full Text Available Fiber tractography on diffusion imaging data offers rich potential for describing white matter pathways in the human brain, but characterizing the spatial organization in these large and complex data sets remains a challenge. We show that level set trees--which provide a concise representation of the hierarchical mode structure of probability density functions--offer a statistically-principled framework for visualizing and analyzing topography in fiber streamlines. Using diffusion spectrum imaging data collected on neurologically healthy controls (N = 30, we mapped white matter pathways from the cortex into the striatum using a deterministic tractography algorithm that estimates fiber bundles as dimensionless streamlines. Level set trees were used for interactive exploration of patterns in the endpoint distributions of the mapped fiber pathways and an efficient segmentation of the pathways that had empirical accuracy comparable to standard nonparametric clustering techniques. We show that level set trees can also be generalized to model pseudo-density functions in order to analyze a broader array of data types, including entire fiber streamlines. Finally, resampling methods show the reliability of the level set tree as a descriptive measure of topographic structure, illustrating its potential as a statistical descriptor in brain imaging analysis. These results highlight the broad applicability of level set trees for visualizing and analyzing high-dimensional data like fiber tractography output.

  15. Closed sets of nonlocal correlations

    International Nuclear Information System (INIS)

    Allcock, Jonathan; Linden, Noah; Brunner, Nicolas; Popescu, Sandu; Skrzypczyk, Paul; Vertesi, Tamas

    2009-01-01

    We present a fundamental concept - closed sets of correlations - for studying nonlocal correlations. We argue that sets of correlations corresponding to information-theoretic principles, or more generally to consistent physical theories, must be closed under a natural set of operations. Hence, studying the closure of sets of correlations gives insight into which information-theoretic principles are genuinely different, and which are ultimately equivalent. This concept also has implications for understanding why quantum nonlocality is limited, and for finding constraints on physical theories beyond quantum mechanics.

  16. A book of set theory

    CERN Document Server

    Pinter, Charles C

    2014-01-01

    Suitable for upper-level undergraduates, this accessible approach to set theory poses rigorous but simple arguments. Each definition is accompanied by commentary that motivates and explains new concepts. Starting with a repetition of the familiar arguments of elementary set theory, the level of abstract thinking gradually rises for a progressive increase in complexity.A historical introduction presents a brief account of the growth of set theory, with special emphasis on problems that led to the development of the various systems of axiomatic set theory. Subsequent chapters explore classes and

  17. Quantum set theory and applications

    International Nuclear Information System (INIS)

    Rodriguez, E.

    1984-01-01

    The work of von Neumann tells us that the logic of quantum mechanics is not Boolenan. This suggests the formulation of a quantum theory of sets based on quantum logic much as modern set theory is based on Boolean logic. In the first part of this dissertation such a quantum set theory is developed. In the second part, quantum set theory is proposed as a universal language for physics. A quantum topology and the beginnings of a quantum geometry are developed in this language. Finally, a toy model is studied. It gives indications of possible lines for progress in this program

  18. SEEPAGE MODEL FOR PA INCLUDING DRIFT COLLAPSE

    International Nuclear Information System (INIS)

    C. Tsang

    2004-01-01

    The purpose of this report is to document the predictions and analyses performed using the seepage model for performance assessment (SMPA) for both the Topopah Spring middle nonlithophysal (Tptpmn) and lower lithophysal (Tptpll) lithostratigraphic units at Yucca Mountain, Nevada. Look-up tables of seepage flow rates into a drift (and their uncertainty) are generated by performing numerical simulations with the seepage model for many combinations of the three most important seepage-relevant parameters: the fracture permeability, the capillary-strength parameter 1/a, and the percolation flux. The percolation flux values chosen take into account flow focusing effects, which are evaluated based on a flow-focusing model. Moreover, multiple realizations of the underlying stochastic permeability field are conducted. Selected sensitivity studies are performed, including the effects of an alternative drift geometry representing a partially collapsed drift from an independent drift-degradation analysis (BSC 2004 [DIRS 166107]). The intended purpose of the seepage model is to provide results of drift-scale seepage rates under a series of parameters and scenarios in support of the Total System Performance Assessment for License Application (TSPA-LA). The SMPA is intended for the evaluation of drift-scale seepage rates under the full range of parameter values for three parameters found to be key (fracture permeability, the van Genuchten 1/a parameter, and percolation flux) and drift degradation shape scenarios in support of the TSPA-LA during the period of compliance for postclosure performance [Technical Work Plan for: Performance Assessment Unsaturated Zone (BSC 2002 [DIRS 160819], Section I-4-2-1)]. The flow-focusing model in the Topopah Spring welded (TSw) unit is intended to provide an estimate of flow focusing factors (FFFs) that (1) bridge the gap between the mountain-scale and drift-scale models, and (2) account for variability in local percolation flux due to

  19. Multilayer Piezoelectric Stack Actuator Characterization

    Science.gov (United States)

    Sherrit, Stewart; Jones, Christopher M.; Aldrich, Jack B.; Blodget, Chad; Bao, Xioaqi; Badescu, Mircea; Bar-Cohen, Yoseph

    2008-01-01

    Future NASA missions are increasingly seeking to use actuators for precision positioning to accuracies of the order of fractions of a nanometer. For this purpose, multilayer piezoelectric stacks are being considered as actuators for driving these precision mechanisms. In this study, sets of commercial PZT stacks were tested in various AC and DC conditions at both nominal and extreme temperatures and voltages. AC signal testing included impedance, capacitance and dielectric loss factor of each actuator as a function of the small-signal driving sinusoidal frequency, and the ambient temperature. DC signal testing includes leakage current and displacement as a function of the applied DC voltage. The applied DC voltage was increased to over eight times the manufacturers' specifications to investigate the correlation between leakage current and breakdown voltage. Resonance characterization as a function of temperature was done over a temperature range of -180C to +200C which generally exceeded the manufacturers' specifications. In order to study the lifetime performance of these stacks, five actuators from one manufacturer were driven by a 60volt, 2 kHz sine-wave for ten billion cycles. The tests were performed using a Lab-View controlled automated data acquisition system that monitored the waveform of the stack electrical current and voltage. The measurements included the displacement, impedance, capacitance and leakage current and the analysis of the experimental results will be presented.

  20. MOCUS, Minimal Cut Sets and Minimal Path Sets from Fault Tree Analysis

    International Nuclear Information System (INIS)

    Fussell, J.B.; Henry, E.B.; Marshall, N.H.

    1976-01-01

    1 - Description of problem or function: From a description of the Boolean failure logic of a system, called a fault tree, and control parameters specifying the minimal cut set length to be obtained MOCUS determines the system failure modes, or minimal cut sets, and the system success modes, or minimal path sets. 2 - Method of solution: MOCUS uses direct resolution of the fault tree into the cut and path sets. The algorithm used starts with the main failure of interest, the top event, and proceeds to basic independent component failures, called primary events, to resolve the fault tree to obtain the minimal sets. A key point of the algorithm is that an and gate alone always increases the number of path sets; an or gate alone always increases the number of cut sets and increases the size of path sets. Other types of logic gates must be described in terms of and and or logic gates. 3 - Restrictions on the complexity of the problem: Output from MOCUS can include minimal cut and path sets for up to 20 gates

  1. Data Programming: Creating Large Training Sets, Quickly

    Science.gov (United States)

    Ratner, Alexander; De Sa, Christopher; Wu, Sen; Selsam, Daniel; Ré, Christopher

    2018-01-01

    Large labeled training sets are the critical building blocks of supervised learning methods and are key enablers of deep learning techniques. For some applications, creating labeled training sets is the most time-consuming and expensive part of applying machine learning. We therefore propose a paradigm for the programmatic creation of training sets called data programming in which users express weak supervision strategies or domain heuristics as labeling functions, which are programs that label subsets of the data, but that are noisy and may conflict. We show that by explicitly representing this training set labeling process as a generative model, we can “denoise” the generated training set, and establish theoretically that we can recover the parameters of these generative models in a handful of settings. We then show how to modify a discriminative loss function to make it noise-aware, and demonstrate our method over a range of discriminative models including logistic regression and LSTMs. Experimentally, on the 2014 TAC-KBP Slot Filling challenge, we show that data programming would have led to a new winning score, and also show that applying data programming to an LSTM model leads to a TAC-KBP score almost 6 F1 points over a state-of-the-art LSTM baseline (and into second place in the competition). Additionally, in initial user studies we observed that data programming may be an easier way for non-experts to create machine learning models when training data is limited or unavailable. PMID:29872252

  2. Automated Experiments on Ad Privacy Settings

    Directory of Open Access Journals (Sweden)

    Datta Amit

    2015-04-01

    Full Text Available To partly address people’s concerns over web tracking, Google has created the Ad Settings webpage to provide information about and some choice over the profiles Google creates on users. We present AdFisher, an automated tool that explores how user behaviors, Google’s ads, and Ad Settings interact. AdFisher can run browser-based experiments and analyze data using machine learning and significance tests. Our tool uses a rigorous experimental design and statistical analysis to ensure the statistical soundness of our results. We use AdFisher to find that the Ad Settings was opaque about some features of a user’s profile, that it does provide some choice on ads, and that these choices can lead to seemingly discriminatory ads. In particular, we found that visiting webpages associated with substance abuse changed the ads shown but not the settings page. We also found that setting the gender to female resulted in getting fewer instances of an ad related to high paying jobs than setting it to male. We cannot determine who caused these findings due to our limited visibility into the ad ecosystem, which includes Google, advertisers, websites, and users. Nevertheless, these results can form the starting point for deeper investigations by either the companies themselves or by regulatory bodies.

  3. Setting up virtual private network

    International Nuclear Information System (INIS)

    Huang Hongmei; Zhang Chengjun

    2003-01-01

    Setting up virtual private network for business enterprise provides a low cost network foundation, increases enterprise's network function and enlarges its private scope. The text introduces virtual private network's principal, privileges and protocols that use in virtual private network. At last, this paper introduces several setting up virtual private network's technologies which based on LAN

  4. Setting up virtual private network

    International Nuclear Information System (INIS)

    Huang Hongmei; Zhang Chengjun

    2003-01-01

    Setting up virtual private network for business enterprise provides a low cost network foundation, increases enterprise network function and enlarges its private scope. This text introduces virtual private network principal, privileges and protocols applied in virtual private network. At last, this paper introduces several setting up virtual private network technologies which is based on LAN

  5. Bankruptcy Prediction with Rough Sets

    NARCIS (Netherlands)

    J.C. Bioch (Cor); V. Popova (Viara)

    2001-01-01

    textabstractThe bankruptcy prediction problem can be considered an or dinal classification problem. The classical theory of Rough Sets describes objects by discrete attributes, and does not take into account the order- ing of the attributes values. This paper proposes a modification of the Rough Set

  6. Gene set analysis of the EADGENE chicken data-set

    DEFF Research Database (Denmark)

    Skarman, Axel; Jiang, Li; Hornshøj, Henrik

    2009-01-01

     Abstract Background: Gene set analysis is considered to be a way of improving our biological interpretation of the observed expression patterns. This paper describes different methods applied to analyse expression data from a chicken DNA microarray dataset. Results: Applying different gene set...... analyses to the chicken expression data led to different ranking of the Gene Ontology terms tested. A method for prediction of possible annotations was applied. Conclusion: Biological interpretation based on gene set analyses dependent on the statistical method used. Methods for predicting the possible...

  7. Ranking Specific Sets of Objects.

    Science.gov (United States)

    Maly, Jan; Woltran, Stefan

    2017-01-01

    Ranking sets of objects based on an order between the single elements has been thoroughly studied in the literature. In particular, it has been shown that it is in general impossible to find a total ranking - jointly satisfying properties as dominance and independence - on the whole power set of objects. However, in many applications certain elements from the entire power set might not be required and can be neglected in the ranking process. For instance, certain sets might be ruled out due to hard constraints or are not satisfying some background theory. In this paper, we treat the computational problem whether an order on a given subset of the power set of elements satisfying different variants of dominance and independence can be found, given a ranking on the elements. We show that this problem is tractable for partial rankings and NP-complete for total rankings.

  8. paleoenvironmental settings and assemblage changes

    African Journals Online (AJOL)

    Kasanzu

    shallow borehole drilled in the southern coastal basin of Tanzania with the aim of characterizing foraminifera and palynomorphs assemblage changes aiming at reconstructing ..... decline in temperature at EOT which caused the extinction of ...

  9. RSO Characterization from Photometric Data Using Machine Learning

    Science.gov (United States)

    Howard, M.; Klem, B.; Gorman, J.

    Object characterization is the description of a resident space object (RSO), its capabilities and its behavior. While astrometric data has been used extensively for object detection, location, and characterization, photometric data has been less widely applied and remains a promising area for improving RSO characterization. RSO characteristics which may influence changes in light intensity with respect to changes in viewing angle or orientation signature include geometry, orientation, components material properties, stability and other characteristics. However, most RSO characterization is presently performed manually and on an individual basis by space analysts and there is a need for efficient and automated methods to perform characterization. This paper discusses the application of machine learning techniques to characterization of RSOs in the geosynchronous altitude regime using photometric data. We develop simulated signatures in the visible spectral band of three basic RSO types, with variations in object orientation, material characteristics, size and attitude and attempt to recover these properties through object characterization techniques. We generate observations by sampling noisy measurements from the simulated signature. Next, we extract a set of features from the observations and train machine learning algorithms to classify the signatures. We consider the effectiveness of a set of binary classifiers trained to individually recognize separate cases. The results of each classifier are combined together to produce a final output characterization of an input observation. Experiments with varying levels of noise are presented, and we evaluate models with respect to classification accuracy and other criteria. The end result of this process is a unique methodology for exploiting the use usefulness and applicability of machine learning to an important space sensing and identification process. This material is based upon work supported by the United States

  10. Search Engine Customization and Data Set Builder

    OpenAIRE

    Arias Moreno, Fco Javier

    2009-01-01

    There are two core objectives in this work: firstly, to build a data set, and secondly, to customize a search engine. The first objective is to design and implement a data set builder. There are two steps required for this. The first step is to build a crawler. The second step is to include a cleaner. The crawler collects Web links. The cleaner extracts the main content and removes noise from the files crawled. The goal of this application is crawling Web news sites to find the...

  11. Microwave Enhanced Cotunneling in SET Transistors

    DEFF Research Database (Denmark)

    Manscher, Martin; Savolainen, M.; Mygind, Jesper

    2003-01-01

    Cotunneling in single electron tunneling (SET) devices is an error process which may severely limit their electronic and metrologic applications. Here is presented an experimental investigation of the theory for adiabatic enhancement of cotunneling by coherent microwaves. Cotunneling in SET...... transistors has been measured as function of temperature, gate voltage, frequency, and applied microwave power. At low temperatures and applied power levels, including also sequential tunneling, the results can be made consistent with theory using the unknown damping in the microwave line as the only free...

  12. Multiple variables data sets visualization in ROOT

    International Nuclear Information System (INIS)

    Couet, O

    2008-01-01

    The ROOT graphical framework provides support for many different functions including basic graphics, high-level visualization techniques, output on files, 3D viewing etc. They use well-known world standards to render graphics on screen, to produce high-quality output files, and to generate images for Web publishing. Many techniques allow visualization of all the basic ROOT data types, but the graphical framework was still a bit weak in the visualization of multiple variables data sets. This paper presents latest developments done in the ROOT framework to visualize multiple variables (>4) data sets

  13. Mixed waste characterization reference document

    International Nuclear Information System (INIS)

    1997-09-01

    Waste characterization and monitoring are major activities in the management of waste from generation through storage and treatment to disposal. Adequate waste characterization is necessary to ensure safe storage, selection of appropriate and effective treatment, and adherence to disposal standards. For some wastes characterization objectives can be difficult and costly to achieve. The purpose of this document is to evaluate costs of characterizing one such waste type, mixed (hazardous and radioactive) waste. For the purpose of this document, waste characterization includes treatment system monitoring, where monitoring is a supplement or substitute for waste characterization. This document establishes a cost baseline for mixed waste characterization and treatment system monitoring requirements from which to evaluate alternatives. The cost baseline established as part of this work includes costs for a thermal treatment technology (i.e., a rotary kiln incinerator), a nonthermal treatment process (i.e., waste sorting, macronencapsulation, and catalytic wet oxidation), and no treatment (i.e., disposal of waste at the Waste Isolation Pilot Plant (WIPP)). The analysis of improvement over the baseline includes assessment of promising areas for technology development in front-end waste characterization, process equipment, off gas controls, and monitoring. Based on this assessment, an ideal characterization and monitoring configuration is described that minimizes costs and optimizes resources required for waste characterization

  14. Benchmark data set for wheat growth models

    DEFF Research Database (Denmark)

    Asseng, S; Ewert, F.; Martre, P

    2015-01-01

    The data set includes a current representative management treatment from detailed, quality-tested sentinel field experiments with wheat from four contrasting environments including Australia, The Netherlands, India and Argentina. Measurements include local daily climate data (solar radiation, max...... analysis with 26 models and 30 years (1981-2010) for each location, for elevated atmospheric CO2 and temperature changes, a heat stress sensitivity analysis at anthesis, and a sensitivity analysis with soil and crop management variations and a Global Climate Model end-century scenario....

  15. Children's health in slum settings.

    Science.gov (United States)

    Unger, Alon

    2013-10-01

    Rapid urbanisation in the 20th century has been accompanied by the development of slums. Nearly one-third of the world's population and more than 60% of urban populations in the least developed countries live in slums, including hundreds of millions of children. Slums are areas of broad social and health disadvantage to children and their families due to extreme poverty, overcrowding, poor water and sanitation, substandard housing, limited access to basic health and education services, and other hardships (eg, high unemployment, violence). Despite the magnitude of this problem, very little is known about the potential impact of slum life on the health of children and adolescents. Statistics that show improved mortality and health outcomes in cities are based on aggregated data and may miss important intraurban disparities. Limited but consistent evidence suggests higher infant and under-five years mortality for children residing in slums compared with non-slum areas. Children suffer from higher rates of diarrhoeal and respiratory illness, malnutrition and have lower vaccination rates. Mothers residing in slums are more poorly educated and less likely to receive antenatal care and skilled birth assistance. Adolescents have earlier sexual debut and higher rates of HIV, and adopt risky behaviours influenced by their social environment. We also know little about the consequences of this form of early childhood on long-term health-related behaviour (eg, diet and exercise) and non-communicable disease outcomes, such as obesity, heart disease and mental illness. Further attention to understanding and addressing child health in slum settings is an important priority for paediatricians and those committed to child health worldwide.

  16. Nuclear data sets for reactor design calculations - approved 1975

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    This standard identifies and describes the specifications for developing, preparing, and documenting nuclear data sets to be used in reactor design calculations. The specifications include (a) criteria for acceptance of evaluated nuclear data sets, (b) criteria for processing evaluated data and preparation of processed continuous data and averaged data sets, and (c) identification of specific evaluated, processed continuous, and averaged data sets which meet these criteria for specific reactor types

  17. American National Standard: nuclear data sets for reactor design calculations

    International Nuclear Information System (INIS)

    1983-01-01

    This standard identifies and describes the specifications for developing, preparing, and documenting nuclear data sets to be used in reactor design calculations. The specifications include criteria for acceptance of evaluated nuclear data sets, criteria for processing evaluated data and preparation of processed continuous data and averaged data sets, and identification of specific evaluated, processed continuous, and averaged data sets which meet these criteria for specific reactor types

  18. American National Standard nuclear data sets for reactor design calculations

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    A standard is presented which identifies and describes the specifications for developing, preparing, and documenting nuclear data sets to be used in reactor design calculations. The specifications include (a) criteria for acceptance of evaluated nuclear data sets, (b) criteria for processing evaluated data and preparation of processed continuous data and averaged data sets, and (c) identification of specific evaluated, processed continuous, and averaged data sets which meet these criteria for specific reactor types

  19. Application of Neutrosophic Set Theory in Generalized Assignment Problem

    Directory of Open Access Journals (Sweden)

    Supriya Kar

    2015-09-01

    Full Text Available This paper presents the application of Neutrosophic Set Theory (NST in solving Generalized Assignment Problem (GAP. GAP has been solved earlier under fuzzy environment. NST is a generalization of the concept of classical set, fuzzy set, interval-valued fuzzy set, intuitionistic fuzzy set. Elements of Neutrosophic set are characterized by a truth-membership function, falsity and also indeterminacy which is a more realistic way of expressing the parameters in real life problem. Here the elements of the cost matrix for the GAP are considered as neutrosophic elements which have not been considered earlier by any other author. The problem has been solved by evaluating score function matrix and then solving it by Extremum Difference Method (EDM [1] to get the optimal assignment. The method has been demonstrated by a suitable numerical example.

  20. Large Sets in Boolean and Non-Boolean Groups and Topology

    Directory of Open Access Journals (Sweden)

    Ol’ga V. Sipacheva

    2017-10-01

    Full Text Available Various notions of large sets in groups, including the classical notions of thick, syndetic, and piecewise syndetic sets and the new notion of vast sets in groups, are studied with emphasis on the interplay between such sets in Boolean groups. Natural topologies closely related to vast sets are considered; as a byproduct, interesting relations between vast sets and ultrafilters are revealed.

  1. SYNTHESIS, SPECTRAL CHARACTERIZATIONS AND ...

    African Journals Online (AJOL)

    Preferred Customer

    A series of 4-chloro-2-[(arylmethylidene)amino]phenols (1–11) including methoxy group ... The structures of the Schiff bases were characterized by FT-IR, .... The characteristic ν(C-H) modes of ring residues are observed at near 3050 cm–1.

  2. Evaluation of Suitability of Selected Set of Coal Plant Sites for Repowering with Small Modular Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Belles, Randy [ORNL; Copinger, Donald A [ORNL; Mays, Gary T [ORNL; Omitaomu, Olufemi A [ORNL; Poore III, Willis P [ORNL

    2013-03-01

    This report summarizes the approach that ORNL developed for screening a sample set of small coal stations for possible repowering with SMRs; the methodology employed, including spatial modeling; and initial results for these sample plants. The objective in conducting this type of siting evaluation is to demonstrate the capability to characterize specific sample coal plant sites to identify any particular issues associated with repowering existing coal stations with SMRs using OR-SAGE; it is not intended to be a definitive assessment per se as to the absolute suitability of any particular site.

  3. Truck Drivers And Risk Of STDs Including HIV

    Directory of Open Access Journals (Sweden)

    Bansal R.K

    1995-01-01

    Full Text Available Research Question: Whether long distance truck drivers are at a higher risk of contracting and transmitting STDs including HIV? Objectives: i To study the degree of knowledge of HIV and AIDS among long- distance truck drivers. ii Assess their sexual behaviour including condom use. iii Explore their prevailing social influences and substance abuse patterns. iv Explore their treatment seeking bahaviour as regards STDs. v Deduce their risk of contracting and transmitting STDs including HIV. Study Design: Cross- sectional interview. Setting: Transport Nagar, Indore (M.P Participants: 210 senior drivers (First drivers and 210 junior drivers (Second drivers. Study Variables: Extra-Marital sexual intercourse, condom usage, past and present history of STDs, treatment and counseling, substance abuse, social â€" cultural milieu. Outcome Variables: Risk of contraction of STDs. Statistical Analysis: Univariate analysis. Results: 94% of the drivers were totally ignorant about AIDS. 82.9% and 43.8 % of the senior and junior drivers had a history of extra- marital sex and of these only 2 regularly used condoms. 13.8% and 3.3 % of the senior and junior drivers had a past or present history suggestive of STD infection. Alcohol and Opium were regularly used by them. Conclusion: The studied drivers are at a high risk of contracting and transmitting STDs including HIV.

  4. Setting-related influences on physical inactivity of older adults in residential care settings: a review.

    Science.gov (United States)

    Douma, Johanna G; Volkers, Karin M; Engels, Gwenda; Sonneveld, Marieke H; Goossens, Richard H M; Scherder, Erik J A

    2017-04-28

    Despite the detrimental effects of physical inactivity for older adults, especially aged residents of residential care settings may spend much time in inactive behavior. This may be partly due to their poorer physical condition; however, there may also be other, setting-related factors that influence the amount of inactivity. The aim of this review was to review setting-related factors (including the social and physical environment) that may contribute to the amount of older adults' physical inactivity in a wide range of residential care settings (e.g., nursing homes, assisted care facilities). Five databases were systematically searched for eligible studies, using the key words 'inactivity', 'care facilities', and 'older adults', including their synonyms and MeSH terms. Additional studies were selected from references used in articles included from the search. Based on specific eligibility criteria, a total of 12 studies were included. Quality of the included studies was assessed using the Mixed Methods Appraisal Tool (MMAT). Based on studies using different methodologies (e.g., interviews and observations), and of different quality (assessed quality range: 25-100%), we report several aspects related to the physical environment and caregivers. Factors of the physical environment that may be related to physical inactivity included, among others, the environment's compatibility with the abilities of a resident, the presence of equipment, the accessibility, security, comfort, and aesthetics of the environment/corridors, and possibly the presence of some specific areas. Caregiver-related factors included staffing levels, the available time, and the amount and type of care being provided. Inactivity levels in residential care settings may be reduced by improving several features of the physical environment and with the help of caregivers. Intervention studies could be performed in order to gain more insight into causal effects of improving setting-related factors on

  5. First-Class Object Sets

    DEFF Research Database (Denmark)

    Ernst, Erik

    Typically, objects are monolithic entities with a fixed interface. To increase the flexibility in this area, this paper presents first-class object sets as a language construct. An object set offers an interface which is a disjoint union of the interfaces of its member objects. It may also be used...... for a special kind of method invocation involving multiple objects in a dynamic lookup process. With support for feature access and late-bound method calls object sets are similar to ordinary objects, only more flexible. The approach is made precise by means of a small calculus, and the soundness of its type...

  6. Setting limits on supersymmetry using simplified models

    CERN Document Server

    Gutschow, C.

    2012-01-01

    Experimental limits on supersymmetry and similar theories are difficult to set because of the enormous available parameter space and difficult to generalize because of the complexity of single points. Therefore, more phenomenological, simplified models are becoming popular for setting experimental limits, as they have clearer physical implications. The use of these simplified model limits to set a real limit on a concrete theory has not, however, been demonstrated. This paper recasts simplified model limits into limits on a specific and complete supersymmetry model, minimal supergravity. Limits obtained under various physical assumptions are comparable to those produced by directed searches. A prescription is provided for calculating conservative and aggressive limits on additional theories. Using acceptance and efficiency tables along with the expected and observed numbers of events in various signal regions, LHC experimental results can be re-cast in this manner into almost any theoretical framework, includ...

  7. Optimal timing for intravascular administration set replacement.

    Science.gov (United States)

    Ullman, Amanda J; Cooke, Marie L; Gillies, Donna; Marsh, Nicole M; Daud, Azlina; McGrail, Matthew R; O'Riordan, Elizabeth; Rickard, Claire M

    2013-09-15

    The tubing (administration set) attached to both venous and arterial catheters may contribute to bacteraemia and other infections. The rate of infection may be increased or decreased by routine replacement of administration sets. This review was originally published in 2005 and was updated in 2012. The objective of this review was to identify any relationship between the frequency with which administration sets are replaced and rates of microbial colonization, infection and death. We searched The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 6), MEDLINE (1950 to June 2012), CINAHL (1982 to June 2012), EMBASE (1980 to June 2012), reference lists of identified trials and bibliographies of published reviews. The original search was performed in February 2004. We also contacted researchers in the field. We applied no language restriction. We included all randomized or controlled clinical trials on the frequency of venous or arterial catheter administration set replacement in hospitalized participants. Two review authors assessed all potentially relevant studies. We resolved disagreements between the two review authors by discussion with a third review author. We collected data for seven outcomes: catheter-related infection; infusate-related infection; infusate microbial colonization; catheter microbial colonization; all-cause bloodstream infection; mortality; and cost. We pooled results from studies that compared different frequencies of administration set replacement, for instance, we pooled studies that compared replacement ≥ every 96 hours versus every 72 hours with studies that compared replacement ≥ every 48 hours versus every 24 hours. We identified 26 studies for this updated review, 10 of which we excluded; six did not fulfil the inclusion criteria and four did not report usable data. We extracted data from the remaining 18 references (16 studies) with 5001 participants: study designs included neonate and adult

  8. Priority setting: what constitutes success? A conceptual framework for successful priority setting.

    Science.gov (United States)

    Sibbald, Shannon L; Singer, Peter A; Upshur, Ross; Martin, Douglas K

    2009-03-05

    The sustainability of healthcare systems worldwide is threatened by a growing demand for services and expensive innovative technologies. Decision makers struggle in this environment to set priorities appropriately, particularly because they lack consensus about which values should guide their decisions. One way to approach this problem is to determine what all relevant stakeholders understand successful priority setting to mean. The goal of this research was to develop a conceptual framework for successful priority setting. Three separate empirical studies were completed using qualitative data collection methods (one-on-one interviews with healthcare decision makers from across Canada; focus groups with representation of patients, caregivers and policy makers; and Delphi study including scholars and decision makers from five countries). This paper synthesizes the findings from three studies into a framework of ten separate but interconnected elements germane to successful priority setting: stakeholder understanding, shifted priorities/reallocation of resources, decision making quality, stakeholder acceptance and satisfaction, positive externalities, stakeholder engagement, use of explicit process, information management, consideration of values and context, and revision or appeals mechanism. The ten elements specify both quantitative and qualitative dimensions of priority setting and relate to both process and outcome components. To our knowledge, this is the first framework that describes successful priority setting. The ten elements identified in this research provide guidance for decision makers and a common language to discuss priority setting success and work toward improving priority setting efforts.

  9. Characterization of organic thin films

    CERN Document Server

    Ulman, Abraham; Evans, Charles A

    2009-01-01

    Thin films based upon organic materials are at the heart of much of the revolution in modern technology, from advanced electronics, to optics to sensors to biomedical engineering. This volume in the Materials Characterization series introduces the major common types of analysis used in characterizing of thin films and the various appropriate characterization technologies for each. Materials such as Langmuir-Blodgett films and self-assembled monolayers are first introduced, followed by analysis of surface properties and the various characterization technologies used for such. Readers will find detailed information on: -Various spectroscopic approaches to characterization of organic thin films, including infrared spectroscopy and Raman spectroscopy -X-Ray diffraction techniques, High Resolution EELS studies, and X-Ray Photoelectron Spectroscopy -Concise Summaries of major characterization technologies for organic thin films, including Auger Electron Spectroscopy, Dynamic Secondary Ion Mass Spectrometry, and Tra...

  10. Guidelines for setting speed limits

    CSIR Research Space (South Africa)

    Wium, DJW

    1986-02-01

    Full Text Available , parking and loading manoeuvres, access to bounding properties, intersections, width of road without central median and clear roadside area. The method should result in greater uniformity in speed limits for similar circumstances as set by different...

  11. Test Program Set (TPS) Lab

    Data.gov (United States)

    Federal Laboratory Consortium — The ARDEC TPS Laboratory provides an organic Test Program Set (TPS) development, maintenance, and life cycle management capability for DoD LCMC materiel developers....

  12. Price setting in turbulent times

    DEFF Research Database (Denmark)

    Ólafsson, Tjörvi; Pétursdóttir, Ásgerdur; Vignisdóttir, Karen Á.

    This price setting survey among Icelandic firms aims to make two contributions to the literature. First, it studies price setting in an advanced economy within a more turbulent macroeconomic environment than has previously been done. The results indicate that price adjustments are to a larger...... extent driven by exchange rate fluctuations than in most other advanced countries. The median Icelandic firm reviews its prices every four months and changes them every six months. The main sources of price rigidity and the most commonly used price setting methods are the same as in most other countries....... A second contribution to the literature is our analysis of the nexus between price setting and exchange rate movements, a topic that has attracted surprisingly limited attention in this survey-based literature. A novel aspect of our approach is to base our analysis on a categorisation of firms...

  13. On Intuitionistic Fuzzy Sets Theory

    CERN Document Server

    Atanassov, Krassimir T

    2012-01-01

    This book aims to be a  comprehensive and accurate survey of state-of-art research on intuitionistic fuzzy sets theory and could be considered a continuation and extension of the author´s previous book on Intuitionistic Fuzzy Sets, published by Springer in 1999 (Atanassov, Krassimir T., Intuitionistic Fuzzy Sets, Studies in Fuzziness and soft computing, ISBN 978-3-7908-1228-2, 1999). Since the aforementioned  book has appeared, the research activity of the author within the area of intuitionistic fuzzy sets has been expanding into many directions. The results of the author´s most recent work covering the past 12 years as well as the newest general ideas and open problems in this field have been therefore collected in this new book.

  14. Agenda-setting the unknown

    DEFF Research Database (Denmark)

    Dannevig, Halvor

    -setting theory, it is concluded that agenda-setting of climate change adaptation requires human agency in providing local legitimacy and salience for the issue. The thesis also finds that boundary arrangements are needed to bridge the gap between local knowledge and scientific knowledge for adaptation governance....... Attempts at such boundary arrangements are already in place at the regional governance levels, but they must be strengthened if municipalities are to take further steps in implementing adaptation measures....

  15. Julia Sets of Orthogonal Polynomials

    DEFF Research Database (Denmark)

    Christiansen, Jacob Stordal; Henriksen, Christian; Petersen, Henrik Laurberg

    2018-01-01

    For a probability measure with compact and non-polar support in the complex plane we relate dynamical properties of the associated sequence of orthogonal polynomials fPng to properties of the support. More precisely we relate the Julia set of Pn to the outer boundary of the support, the lled Julia...... set to the polynomial convex hull K of the support, and the Green's function associated with Pn to the Green's function for the complement of K....

  16. Sets with Prescribed Arithmetic Densities

    Czech Academy of Sciences Publication Activity Database

    Luca, F.; Pomerance, C.; Porubský, Štefan

    2008-01-01

    Roč. 3, č. 2 (2008), s. 67-80 ISSN 1336-913X R&D Projects: GA ČR GA201/07/0191 Institutional research plan: CEZ:AV0Z10300504 Keywords : generalized arithmetic density * generalized asymptotic density * generalized logarithmic density * arithmetical semigroup * weighted arithmetic mean * ratio set * R-dense set * Axiom A * delta-regularly varying function Subject RIV: BA - General Mathematics

  17. Philosophical introduction to set theory

    CERN Document Server

    Pollard, Stephen

    2015-01-01

    The primary mechanism for ideological and theoretical unification in modern mathematics, set theory forms an essential element of any comprehensive treatment of the philosophy of mathematics. This unique approach to set theory offers a technically informed discussion that covers a variety of philosophical issues. Rather than focusing on intuitionist and constructive alternatives to the Cantorian/Zermelian tradition, the author examines the two most important aspects of the current philosophy of mathematics, mathematical structuralism and mathematical applications of plural reference and plural

  18. Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.

    Science.gov (United States)

    Shinsky, Stephen A; Monteith, Kelsey E; Viggiano, Susan; Cosgrove, Michael S

    2015-03-06

    Mixed lineage leukemia protein-1 (MLL1) is a member of the SET1 family of histone H3 lysine 4 (H3K4) methyltransferases that are required for metazoan development. MLL1 is the best characterized human SET1 family member, which includes MLL1-4 and SETd1A/B. MLL1 assembles with WDR5, RBBP5, ASH2L, DPY-30 (WRAD) to form the MLL1 core complex, which is required for H3K4 dimethylation and transcriptional activation. Because all SET1 family proteins interact with WRAD in vivo, it is hypothesized they are regulated by similar mechanisms. However, recent evidence suggests differences among family members that may reflect unique regulatory inputs in the cell. Missing is an understanding of the intrinsic enzymatic activities of different SET1 family complexes under standard conditions. In this investigation, we reconstituted each human SET1 family core complex and compared subunit assembly and enzymatic activities. We found that in the absence of WRAD, all but one SET domain catalyzes at least weak H3K4 monomethylation. In the presence of WRAD, all SET1 family members showed stimulated monomethyltransferase activity but differed in their di- and trimethylation activities. We found that these differences are correlated with evolutionary lineage, suggesting these enzyme complexes have evolved to accomplish unique tasks within metazoan genomes. To understand the structural basis for these differences, we employed a "phylogenetic scanning mutagenesis" assay and identified a cluster of amino acid substitutions that confer a WRAD-dependent gain-of-function dimethylation activity on complexes assembled with the MLL3 or Drosophila trithorax proteins. These results form the basis for understanding how WRAD differentially regulates SET1 family complexes in vivo. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. Ionic liquids, electrolyte solutions including the ionic liquids, and energy storage devices including the ionic liquids

    Science.gov (United States)

    Gering, Kevin L.; Harrup, Mason K.; Rollins, Harry W.

    2015-12-08

    An ionic liquid including a phosphazene compound that has a plurality of phosphorus-nitrogen units and at least one pendant group bonded to each phosphorus atom of the plurality of phosphorus-nitrogen units. One pendant group of the at least one pendant group comprises a positively charged pendant group. Additional embodiments of ionic liquids are disclosed, as are electrolyte solutions and energy storage devices including the embodiments of the ionic liquid.

  20. An introduction to random sets

    CERN Document Server

    Nguyen, Hung T

    2006-01-01

    The study of random sets is a large and rapidly growing area with connections to many areas of mathematics and applications in widely varying disciplines, from economics and decision theory to biostatistics and image analysis. The drawback to such diversity is that the research reports are scattered throughout the literature, with the result that in science and engineering, and even in the statistics community, the topic is not well known and much of the enormous potential of random sets remains untapped.An Introduction to Random Sets provides a friendly but solid initiation into the theory of random sets. It builds the foundation for studying random set data, which, viewed as imprecise or incomplete observations, are ubiquitous in today''s technological society. The author, widely known for his best-selling A First Course in Fuzzy Logic text as well as his pioneering work in random sets, explores motivations, such as coarse data analysis and uncertainty analysis in intelligent systems, for studying random s...

  1. Setting MEPS for electronic products

    International Nuclear Information System (INIS)

    Siderius, Hans-Paul

    2014-01-01

    When analysing price, performance and efficiency data for 15 consumer electronic and information and communication technology products, we found that in general price did not relate to the efficiency of the product. Prices of electronic products with comparable performance decreased over time. For products where the data allowed fitting the relationship, we found an exponential decrease in price with an average time constant of −0.30 [1/year], meaning that every year the product became 26% cheaper on average. The results imply that the classical approach of setting minimum efficiency performance standards (MEPS) by means of life cycle cost calculations cannot be applied to electronic products. Therefore, an alternative approach based on the improvement of efficiency over time and the variation in efficiency of products on the market, is presented. The concept of a policy action window can provide guidance for the decision on whether setting MEPS for a certain product is appropriate. If the (formal) procedure for setting MEPS takes longer than the policy action window, this means that the efficiency improvement will also be achieved without setting MEPS. We found short, i.e. less than three years, policy action windows for graphic cards, network attached storage products, network switches and televisions. - Highlights: • For electronic consumer products price does not relate to efficiency. • Average price decrease of selected electronic products is 26 % per year. • We give an alternative approach to life cycle cost calculations for setting MEPS. • The policy action window indicates whether setting MEPS is appropriate

  2. Characterizing multifragmentation

    International Nuclear Information System (INIS)

    Campi, X.; Krivine, H.

    1994-01-01

    Various methods to characterize the fragment size distributions in nuclear multifragmentation are discussed. The goal is to find the best signals of a phase transition associated to multifragmentation. The concepts of scaling and critical exponents are reviewed and the possibility to determine them in finite nuclei is examined. The fluctuations of the fragment size distribution and a possible signal of intermittency are also discussed. (author). 29 refs., 4 figs., 1 tab

  3. X fluorescence spectrometer including at least one toroidal monochromator with logarithmic spiral

    International Nuclear Information System (INIS)

    Florestan, J.

    1986-01-01

    This spectrometer includes a X-ray source, an entrance diaphragm, a revolution monochromator with monocrystal thin plates and a seal set in its center, an outer diaphragm and a X-ray detector. A second monochromator can be set between the source and the sample. The thin plates are set so as to be a toroidal ring whose cross section in an axial plane describes a logarithmic spiral [fr

  4. Set-Pi: Set Membership pi-Calculus

    DEFF Research Database (Denmark)

    Bruni, Alessandro; Mödersheim, Sebastian Alexander; Nielson, Flemming

    2015-01-01

    Communication protocols often rely on stateful mechanisms to ensure certain security properties. For example, counters and timestamps can be used to ensure authentication, or the security of communication can depend on whether a particular key is registered to a server or it has been revoked. Pro......Verif, like other state of the art tools for protocol analysis, achieves good performance by converting a formal protocol specification into a set of Horn clauses, that represent a monotonically growing set of facts that a Dolev-Yao attacker can derive from the system. Since this set of facts is not state...... method with three examples, a simple authentication protocol based on counters, a key registration protocol, and a model of the Yubikey security device....

  5. Extending Primitive Spatial Data Models to Include Semantics

    Science.gov (United States)

    Reitsma, F.; Batcheller, J.

    2009-04-01

    Our traditional geospatial data model involves associating some measurable quality, such as temperature, or observable feature, such as a tree, with a point or region in space and time. When capturing data we implicitly subscribe to some kind of conceptualisation. If we can make this explicit in an ontology and associate it with the captured data, we can leverage formal semantics to reason with the concepts represented in our spatial data sets. To do so, we extend our fundamental representation of geospatial data in a data model by including a URI in our basic data model that links it to our ontology defining our conceptualisation, We thus extend Goodchild et al's geo-atom [1] with the addition of a URI: (x, Z, z(x), URI) . This provides us with pixel or feature level knowledge and the ability to create layers of data from a set of pixels or features that might be drawn from a database based on their semantics. Using open source tools, we present a prototype that involves simple reasoning as a proof of concept. References [1] M.F. Goodchild, M. Yuan, and T.J. Cova. Towards a general theory of geographic representation in gis. International Journal of Geographical Information Science, 21(3):239-260, 2007.

  6. The impact of the EUSCLE Core Set Questionnaire for the assessment of cutaneous lupus erythematosus.

    Science.gov (United States)

    Kuhn, A; Patsinakidis, N; Bonsmann, G

    2010-08-01

    Epidemiological data and standard European guidelines for the diagnosis and treatment of cutaneous lupus erythematosus (CLE) are lacking in the current literature. In order to provide a standardized tool for an extensive consistent data collection, a study group of the European Society of Cutaneous Lupus Erythematosus (EUSCLE) recently developed a Core Set Questionnaire for the assessment of patients with different subtypes of CLE. The EUSCLE Core Set Questionnaire includes six sections on patient data, diagnosis, skin involvement, activity and damage of disease, laboratory analysis, and treatment. An instrument like the EUSCLE Core Set Questionnaire is essential to gain a broad and comparable data collection of patients with CLE from different European centres and to achieve consensus concerning clinical standards for the disease. The data will also be important for further characterization of the different CLE subtypes and the evaluation of therapeutic strategies; moreover, the EUSCLE Core Set Questionnaire might also be useful for the comparison of data in clinical trials. In this review, the impact of the EUSCLE Core Set Questionnaire is discussed in detail with regard to clinical and serological features as well as therapeutic modalities in CLE.

  7. Hierarchical sets: analyzing pangenome structure through scalable set visualizations

    Science.gov (United States)

    2017-01-01

    Abstract Motivation: The increase in available microbial genome sequences has resulted in an increase in the size of the pangenomes being analyzed. Current pangenome visualizations are not intended for the pangenome sizes possible today and new approaches are necessary in order to convert the increase in available information to increase in knowledge. As the pangenome data structure is essentially a collection of sets we explore the potential for scalable set visualization as a tool for pangenome analysis. Results: We present a new hierarchical clustering algorithm based on set arithmetics that optimizes the intersection sizes along the branches. The intersection and union sizes along the hierarchy are visualized using a composite dendrogram and icicle plot, which, in pangenome context, shows the evolution of pangenome and core size along the evolutionary hierarchy. Outlying elements, i.e. elements whose presence pattern do not correspond with the hierarchy, can be visualized using hierarchical edge bundles. When applied to pangenome data this plot shows putative horizontal gene transfers between the genomes and can highlight relationships between genomes that is not represented by the hierarchy. We illustrate the utility of hierarchical sets by applying it to a pangenome based on 113 Escherichia and Shigella genomes and find it provides a powerful addition to pangenome analysis. Availability and Implementation: The described clustering algorithm and visualizations are implemented in the hierarchicalSets R package available from CRAN (https://cran.r-project.org/web/packages/hierarchicalSets) Contact: thomasp85@gmail.com Supplementary information: Supplementary data are available at Bioinformatics online. PMID:28130242

  8. Maximal Abelian sets of roots

    CERN Document Server

    Lawther, R

    2018-01-01

    In this work the author lets \\Phi be an irreducible root system, with Coxeter group W. He considers subsets of \\Phi which are abelian, meaning that no two roots in the set have sum in \\Phi \\cup \\{ 0 \\}. He classifies all maximal abelian sets (i.e., abelian sets properly contained in no other) up to the action of W: for each W-orbit of maximal abelian sets we provide an explicit representative X, identify the (setwise) stabilizer W_X of X in W, and decompose X into W_X-orbits. Abelian sets of roots are closely related to abelian unipotent subgroups of simple algebraic groups, and thus to abelian p-subgroups of finite groups of Lie type over fields of characteristic p. Parts of the work presented here have been used to confirm the p-rank of E_8(p^n), and (somewhat unexpectedly) to obtain for the first time the 2-ranks of the Monster and Baby Monster sporadic groups, together with the double cover of the latter. Root systems of classical type are dealt with quickly here; the vast majority of the present work con...

  9. Kabuki syndrome: expanding the phenotype to include microphthalmia and anophthalmia.

    Science.gov (United States)

    McVeigh, Terri P; Banka, Siddharth; Reardon, William

    2015-10-01

    Kabuki syndrome is a rare genetic malformation syndrome that is characterized by distinct facies, structural defects and intellectual disability. Kabuki syndrome may be caused by mutations in one of two histone methyltransferase genes: KMT2D and KDM6A. We describe a male child of nonconsanguineous Irish parents presenting with multiple malformations, including bilateral extreme microphthalmia; cleft palate; congenital diaphragmatic hernia; duplex kidney; as well as facial features of Kabuki syndrome, including interrupted eyebrows and lower lid ectropion. A de-novo germline mutation in KMT2D was identified. Whole-exome sequencing failed to reveal mutations in any of the known microphthalmia/anopthalmia genes. We also identified four other patients with Kabuki syndrome and microphthalmia. We postulate that Kabuki syndrome may produce this type of ocular phenotype as a result of extensive interaction between KMT2D, WAR complex proteins and PAXIP1. Children presenting with microphthalmia/anophthalmia should be examined closely for other signs of Kabuki syndrome, especially at an age where the facial gestalt might be less readily appreciable.

  10. Optimal timing for intravenous administration set replacement.

    Science.gov (United States)

    Gillies, D; O'Riordan, L; Wallen, M; Morrison, A; Rankin, K; Nagy, S

    2005-10-19

    Administration of intravenous therapy is a common occurrence within the hospital setting. Routine replacement of administration sets has been advocated to reduce intravenous infusion contamination. If decreasing the frequency of changing intravenous administration sets does not increase infection rates, a change in practice could result in considerable cost savings. The objective of this review was to identify the optimal interval for the routine replacement of intravenous administration sets when infusate or parenteral nutrition (lipid and non-lipid) solutions are administered to people in hospital via central or peripheral venous catheters. We searched The Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, CINAHL, EMBASE: all from inception to February 2004; reference lists of identified trials, and bibliographies of published reviews. We also contacted researchers in the field. We did not have a language restriction. We included all randomized or quasi-randomized controlled trials addressing the frequency of replacing intravenous administration sets when parenteral nutrition (lipid and non-lipid containing solutions) or infusions (excluding blood) were administered to people in hospital via a central or peripheral catheter. Two authors assessed all potentially relevant studies. We resolved disagreements between the two authors by discussion with a third author. We collected data for the outcomes; infusate contamination; infusate-related bloodstream infection; catheter contamination; catheter-related bloodstream infection; all-cause bloodstream infection and all-cause mortality. We identified 23 references for review. We excluded eight of these studies; five because they did not fit the inclusion criteria and three because of inadequate data. We extracted data from the remaining 15 references (13 studies) with 4783 participants. We conclude that there is no evidence that changing intravenous administration sets more often than every 96 hours

  11. Catalyst support structure, catalyst including the structure, reactor including a catalyst, and methods of forming same

    Science.gov (United States)

    Van Norman, Staci A.; Aston, Victoria J.; Weimer, Alan W.

    2017-05-09

    Structures, catalysts, and reactors suitable for use for a variety of applications, including gas-to-liquid and coal-to-liquid processes and methods of forming the structures, catalysts, and reactors are disclosed. The catalyst material can be deposited onto an inner wall of a microtubular reactor and/or onto porous tungsten support structures using atomic layer deposition techniques.

  12. Studying constructions of national identity across historical settings

    DEFF Research Database (Denmark)

    Ydesen, Christian; Øland, Trine

    2018-01-01

    , and national self-imagery. The first setting is the first decade after World War II and the second setting is the post-9/11 era. The empirical focus is based on sources pertaining to the way police officers and related professionals of the Danish welfare nation-state construct disturbing behavior and how......This article aims to demonstrate how constructions of national identity can be studied across historical settings. In this sense, the article contributes knowledge about how Danish-ness is constructed in two historical settings characterized by great upheavals in popular moral codes, culture...... these constructions are made into categories that activate an array of interventions. Using a comparative outlook between the two historical settings and by putting theoretically guided questions to work empirically, the purpose of this article is to understand 1) the boundaries of legitimate behavior and membership...

  13. 41 CFR 102-37.150 - What must a State legislature include in the plan?

    Science.gov (United States)

    2010-07-01

    ... set forth in Appendix B of this part. It may also include in the plan other provisions not inconsistent with the purposes of title 40 of the United States Code and the requirements of this part. [67 FR...

  14. International urinary tract imaging basic spinal cord injury data set

    DEFF Research Database (Denmark)

    Biering-Sørensen, F; Craggs, M; Kennelly, M

    2008-01-01

    OBJECTIVE: To create an International Urinary Tract Imaging Basic Spinal Cord Injury (SCI) Data Set within the framework of the International SCI Data Sets. SETTING: An international working group. METHODS: The draft of the Data Set was developed by a working group comprising members appointed...... of comparable minimal data. RESULTS: The variables included in the International Urinary Tract Imaging Basic SCI Data Set are the results obtained using the following investigations: intravenous pyelography or computer tomography urogram or ultrasound, X-ray, renography, clearance, cystogram, voiding cystogram...

  15. Task representation in individual and joint settings

    Directory of Open Access Journals (Sweden)

    Wolfgang ePrinz

    2015-05-01

    Full Text Available This paper outlines a framework for task representation and discusses applications to interference tasks in individual and joint settings. The framework is derived from the Theory of Event Coding. This theory regards task sets as transient assemblies of event codes in which stimulus and response codes interact and shape each other in particular ways. On the one hand, stimulus and response codes compete with each other within their respective subsets (horizontal interactions. On the other hand, stimulus and response code cooperate with each other (vertical interactions. Code interactions instantiating competition and cooperation apply to two time scales: on-line performance (i.e., doing the task and off-line implementation (i.e., setting the task. Interference arises when stimulus and response codes overlap in features that are irrelevant for stimulus identification, but relevant for response selection. To resolve this dilemma, the feature profiles of event codes may become restructured in various ways. The framework is applied to three kinds of interference paradigms. Special emphasis is given to joint settings where tasks are shared between two participants. Major conclusions derived from these applications include: (1 Response competition is the chief driver of interference. Likewise, different modes of response competition give rise to different patterns of interference. (2 The type of features in which stimulus and response codes overlap is also a crucial factor. Different types of such features give likewise rise to different patterns of interference. (3 Task sets for joint settings conflate intraindividual conflicts between responses (what, with interindividual conflicts between responding agents (whom. Features of response codes may, therefore, not only address responses, but also responding agents (both physically and socially.

  16. Task representation in individual and joint settings

    Science.gov (United States)

    Prinz, Wolfgang

    2015-01-01

    This paper outlines a framework for task representation and discusses applications to interference tasks in individual and joint settings. The framework is derived from the Theory of Event Coding (TEC). This theory regards task sets as transient assemblies of event codes in which stimulus and response codes interact and shape each other in particular ways. On the one hand, stimulus and response codes compete with each other within their respective subsets (horizontal interactions). On the other hand, stimulus and response code cooperate with each other (vertical interactions). Code interactions instantiating competition and cooperation apply to two time scales: on-line performance (i.e., doing the task) and off-line implementation (i.e., setting the task). Interference arises when stimulus and response codes overlap in features that are irrelevant for stimulus identification, but relevant for response selection. To resolve this dilemma, the feature profiles of event codes may become restructured in various ways. The framework is applied to three kinds of interference paradigms. Special emphasis is given to joint settings where tasks are shared between two participants. Major conclusions derived from these applications include: (1) Response competition is the chief driver of interference. Likewise, different modes of response competition give rise to different patterns of interference; (2) The type of features in which stimulus and response codes overlap is also a crucial factor. Different types of such features give likewise rise to different patterns of interference; and (3) Task sets for joint settings conflate intraindividual conflicts between responses (what), with interindividual conflicts between responding agents (whom). Features of response codes may, therefore, not only address responses, but also responding agents (both physically and socially). PMID:26029085

  17. Setting to earth for computer

    International Nuclear Information System (INIS)

    Gallego V, Luis Eduardo; Montana Ch, Johny Hernan; Tovar P, Andres Fernando; Amortegui, Francisco

    2000-01-01

    The program GMT allows the analysis of setting to earth for tensions DC and AC (of low frequency) of diverse configurations composed by cylindrical electrodes interconnected, in a homogeneous land or stratified (two layers). This analysis understands among other aspects: calculation of the setting resistance to earth, elevation of potential of the system (GPR), calculation of current densities in the conductors, potentials calculation in which point on the land surface (profile and surfaces), tensions calculation in passing and of contact, also, it carries out the interpretation of resistivity measures for Wenner and Schlumberger methods, finding a model of two layers

  18. Recommendation Sets and Choice Queries

    DEFF Research Database (Denmark)

    Viappiani, Paolo Renato; Boutilier, Craig

    2011-01-01

    Utility elicitation is an important component of many applications, such as decision support systems and recommender systems. Such systems query users about their preferences and offer recommendations based on the system's belief about the user's utility function. We analyze the connection between...... the problem of generating optimal recommendation sets and the problem of generating optimal choice queries, considering both Bayesian and regret-based elicitation. Our results show that, somewhat surprisingly, under very general circumstances, the optimal recommendation set coincides with the optimal query....

  19. Surgical Instrument Sets for Special Operations Expeditionary Surgical Teams.

    Science.gov (United States)

    Hale, Diane F; Sexton, Justin C; Benavides, Linda C; Benavides, Jerry M; Lundy, Jonathan B

    The deployment of surgical assets has been driven by mission demands throughout years of military operations in Iraq and Afghanistan. The transition to the highly expeditious Golden Hour Offset Surgical Transport Team (GHOST- T) now offers highly mobile surgical assets in nontraditional operating rooms; the content of the surgical instrument sets has also transformed to accommodate this change. The 102nd Forward Surgical Team (FST) was attached to Special Operations assigned to southern Afghanistan from June 2015 to March 2016. The focus was to decrease overall size and weight of FST instrument sets without decreasing surgical capability of the GHOST-T. Each instrument set was evaluated and modified to include essential instruments to perform damage control surgery. The overall number of main instrument sets was decreased from eight to four; simplified augmentation sets have been added, which expand the capabilities of any main set. The overall size was decreased by 40% and overall weight decreased by 58%. The cardiothoracic, thoracotomy, and emergency thoracotomy trays were condensed to thoracic set. The orthopedic and amputation sets were replaced with an augmentation set of a prepackaged orthopedic external fixator set). An augmentation set to the major or minor basic sets, specifically for vascular injuries, was created. Through the reorganization of conventional FST surgical instrument sets to maintain damage control capabilities and mobility, the 102nd GHOST-T reduced surgical equipment volume and weight, providing a lesson learned for future surgical teams operating in austere environments. 2017.

  20. Launch Lock Assemblies Including Axial Gap Amplification Devices and Spacecraft Isolation Systems Including the Same

    Science.gov (United States)

    Barber, Tim Daniel (Inventor); Hindle, Timothy (Inventor); Young, Ken (Inventor); Davis, Torey (Inventor)

    2014-01-01

    Embodiments of a launch lock assembly are provided, as are embodiments of a spacecraft isolation system including one or more launch lock assemblies. In one embodiment, the launch lock assembly includes first and second mount pieces, a releasable clamp device, and an axial gap amplification device. The releasable clamp device normally maintains the first and second mount pieces in clamped engagement; and, when actuated, releases the first and second mount pieces from clamped engagement to allow relative axial motion there between. The axial gap amplification device normally residing in a blocking position wherein the gap amplification device obstructs relative axial motion between the first and second mount pieces. The axial gap amplification device moves into a non-blocking position when the first and second mount pieces are released from clamped engagement to increase the range of axial motion between the first and second mount pieces.

  1. On Fuzzy β-I-open sets and Fuzzy β-I-continuous functions

    International Nuclear Information System (INIS)

    Keskin, Aynur

    2009-01-01

    In this paper, first of all we obtain some properties and characterizations of fuzzy β-I-open sets. After that, we also define the notion of β-I-closed sets and obtain some properties. Lastly, we introduce the notions of fuzzy β-I-continuity with the help of fuzzy β-I-open sets to obtain decomposition of fuzzy continuity.

  2. On Fuzzy {beta}-I-open sets and Fuzzy {beta}-I-continuous functions

    Energy Technology Data Exchange (ETDEWEB)

    Keskin, Aynur [Department of Mathematics, Faculty of Science and Arts, Selcuk University, Campus, 42075 Konya (Turkey)], E-mail: akeskin@selcuk.edu.tr

    2009-11-15

    In this paper, first of all we obtain some properties and characterizations of fuzzy {beta}-I-open sets. After that, we also define the notion of {beta}-I-closed sets and obtain some properties. Lastly, we introduce the notions of fuzzy {beta}-I-continuity with the help of fuzzy {beta}-I-open sets to obtain decomposition of fuzzy continuity.

  3. Phenotypes in defined genotypes including siblings with Usher syndrome.

    Science.gov (United States)

    Malm, Eva; Ponjavic, Vesna; Möller, Claes; Kimberling, William J; Andréasson, Sten

    2011-06-01

    To characterize visual function in defined genotypes including siblings with Usher syndrome. Thirteen patients with phenotypically different subtypes of Usher syndrome, including 3 families with affected siblings, were selected. Genetic analysis and ophthalmological examinations including visual fields, full-field electroretinography (ERG), multifocal electroretinography (mf ERG), and optical coherence tomography (OCT) were assessed. The patients' degree of visual handicap was evaluated by a questionnaire (ADL). Twelve of thirteen patients were genotyped as Usher 1B, 1D, 1F, 2A, 2C or 3A. In 12 of 13 patients examined with ERG the 30 Hz flickering light response revealed remaining cone function. In 3 of the patients with Usher type 1 mf ERG demonstrated a specific pattern, with a sharp distinction between the area with reduced function and the central area with remaining macular function and normal peak time. OCT demonstrated loss of foveal depression with distortion of the foveal architecture in the macula in all patients. The foveal thickness ranged from 159 to 384 µm and was not correlated to retinal function. Three siblings shared the same mutation for Usher 2C but in contrast to previous reports regarding this genotype, 1 of them diverged in phenotype with substantially normal visual fields, almost normal OCT and mf ERG findings, and only moderately reduced rod and cone function according to ERG. Evaluation of visual function comprising both the severity of the rod cone degeneration and the function in the macular region confirm phenotypical heterogeneity within siblings and between different genotypes of Usher syndrome.

  4. Characterizing locally distinguishable orthogonal product states

    OpenAIRE

    Feng, Yuan; Shi, Yaoyun

    2007-01-01

    Bennett et al. \\cite{BDF+99} identified a set of orthogonal {\\em product} states in the $3\\otimes 3$ Hilbert space such that reliably distinguishing those states requires non-local quantum operations. While more examples have been found for this counter-intuitive ``nonlocality without entanglement'' phenomenon, a complete and computationally verifiable characterization for all such sets of states remains unknown. In this Letter, we give such a characterization for the $3\\otimes 3$ space.

  5. STATISTICAL CHARACTERIZATION OF THE CHANDRA SOURCE CATALOG

    International Nuclear Information System (INIS)

    Primini, Francis A.; Evans, Ian N.; Glotfelty, Kenny J.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G.; Grier, John D.; Hain, Roger M.; Harbo, Peter N.; He Xiangqun; Karovska, Margarita; Houck, John C.; Davis, John E.; Nowak, Michael A.; Hall, Diane M.

    2011-01-01

    The first release of the Chandra Source Catalog (CSC) contains ∼95,000 X-ray sources in a total area of 0.75% of the entire sky, using data from ∼3900 separate ACIS observations of a multitude of different types of X-ray sources. In order to maximize the scientific benefit of such a large, heterogeneous data set, careful characterization of the statistical properties of the catalog, i.e., completeness, sensitivity, false source rate, and accuracy of source properties, is required. Characterization efforts of other large Chandra catalogs, such as the ChaMP Point Source Catalog or the 2 Mega-second Deep Field Surveys, while informative, cannot serve this purpose, since the CSC analysis procedures are significantly different and the range of allowable data is much less restrictive. We describe here the characterization process for the CSC. This process includes both a comparison of real CSC results with those of other, deeper Chandra catalogs of the same targets and extensive simulations of blank-sky and point-source populations.

  6. Statistical Characterization of the Chandra Source Catalog

    Science.gov (United States)

    Primini, Francis A.; Houck, John C.; Davis, John E.; Nowak, Michael A.; Evans, Ian N.; Glotfelty, Kenny J.; Anderson, Craig S.; Bonaventura, Nina R.; Chen, Judy C.; Doe, Stephen M.; Evans, Janet D.; Fabbiano, Giuseppina; Galle, Elizabeth C.; Gibbs, Danny G.; Grier, John D.; Hain, Roger M.; Hall, Diane M.; Harbo, Peter N.; He, Xiangqun Helen; Karovska, Margarita; Kashyap, Vinay L.; Lauer, Jennifer; McCollough, Michael L.; McDowell, Jonathan C.; Miller, Joseph B.; Mitschang, Arik W.; Morgan, Douglas L.; Mossman, Amy E.; Nichols, Joy S.; Plummer, David A.; Refsdal, Brian L.; Rots, Arnold H.; Siemiginowska, Aneta; Sundheim, Beth A.; Tibbetts, Michael S.; Van Stone, David W.; Winkelman, Sherry L.; Zografou, Panagoula

    2011-06-01

    The first release of the Chandra Source Catalog (CSC) contains ~95,000 X-ray sources in a total area of 0.75% of the entire sky, using data from ~3900 separate ACIS observations of a multitude of different types of X-ray sources. In order to maximize the scientific benefit of such a large, heterogeneous data set, careful characterization of the statistical properties of the catalog, i.e., completeness, sensitivity, false source rate, and accuracy of source properties, is required. Characterization efforts of other large Chandra catalogs, such as the ChaMP Point Source Catalog or the 2 Mega-second Deep Field Surveys, while informative, cannot serve this purpose, since the CSC analysis procedures are significantly different and the range of allowable data is much less restrictive. We describe here the characterization process for the CSC. This process includes both a comparison of real CSC results with those of other, deeper Chandra catalogs of the same targets and extensive simulations of blank-sky and point-source populations.

  7. Proposal to Include Electrical Energy in the Industrial Return Statistics

    CERN Document Server

    2003-01-01

    At its 108th session on the 20 June 1997, the Council approved the Report of the Finance Committee Working Group on the Review of CERN Purchasing Policy and Procedures. Among other topics, the report recommended the inclusion of utility supplies in the calculation of the return statistics as soon as the relevant markets were deregulated, without reaching a consensus on the exact method of calculation. At its 296th meeting on the 18 June 2003, the Finance Committee approved a proposal to award a contract for the supply of electrical energy (CERN/FC/4693). The purpose of the proposal in this document is to clarify the way electrical energy will be included in future calculations of the return statistics. The Finance Committee is invited: 1. to agree that the full cost to CERN of electrical energy (excluding the cost of transport) be included in the Industrial Service return statistics; 2. to recommend that the Council approves the corresponding amendment to the Financial Rules set out in section 2 of this docum...

  8. Parameter setting and input reduction

    NARCIS (Netherlands)

    Evers, A.; van Kampen, N.J.|info:eu-repo/dai/nl/126439737

    2008-01-01

    The language acquisition procedure identifies certain properties of the target grammar before others. The evidence from the input is processed in a stepwise order. Section 1 equates that order and its typical effects with an order of parameter setting. The question is how the acquisition procedure

  9. Filtration set for gaseous fluids

    International Nuclear Information System (INIS)

    Lebrun, B.; Couvrat-Desvergnes, A.

    1988-01-01

    This filtration set is made by a cylindrical vessel containing upstairs to downstairs, the gas inlet, a sealed floor for man inspection, a horizontal granular filter bed, a linen with a porosity inferior to the granulometry of the filter bed, a light support layer of material of larger granulometry, gas permeable tubes and an annular collector connecting the tubes to the outlet [fr

  10. Fuzzy-Set Case Studies

    Science.gov (United States)

    Mikkelsen, Kim Sass

    2017-01-01

    Contemporary case studies rely on verbal arguments and set theory to build or evaluate theoretical claims. While existing procedures excel in the use of qualitative information (information about kind), they ignore quantitative information (information about degree) at central points of the analysis. Effectively, contemporary case studies rely on…

  11. The IRI marketing data set

    NARCIS (Netherlands)

    Bronnenberg, B.J.; Kruger, M.W.; Mela, C.

    2008-01-01

    This paper describes a new data set available to academic researchers (at the following website: http://mktsci.pubs.informs.org). These data are comprised of store sales and consumer panel data for 30 product categories. The store sales data contain 5 years of product sales, pricing, and promotion

  12. Repeated Interaction in Standard Setting

    NARCIS (Netherlands)

    Larouche, Pierre; Schütt, Florian

    2016-01-01

    As part of the standard-setting process, certain patents become essential. This may allow the owners of these standard-essential patents to hold up implementers of the standard, who can no longer turn to substitute technologies. However, many real-world standards evolve over time, with several

  13. Overcoming Barriers in Unhealthy Settings

    Directory of Open Access Journals (Sweden)

    Michael K. Lemke

    2016-03-01

    Full Text Available We investigated the phenomenon of sustained health-supportive behaviors among long-haul commercial truck drivers, who belong to an occupational segment with extreme health disparities. With a focus on setting-level factors, this study sought to discover ways in which individuals exhibit resiliency while immersed in endemically obesogenic environments, as well as understand setting-level barriers to engaging in health-supportive behaviors. Using a transcendental phenomenological research design, 12 long-haul truck drivers who met screening criteria were selected using purposeful maximum sampling. Seven broad themes were identified: access to health resources, barriers to health behaviors, recommended alternative settings, constituents of health behavior, motivation for health behaviors, attitude toward health behaviors, and trucking culture. We suggest applying ecological theories of health behavior and settings approaches to improve driver health. We also propose the Integrative and Dynamic Healthy Commercial Driving (IDHCD paradigm, grounded in complexity science, as a new theoretical framework for improving driver health outcomes.

  14. Behavior Management in Afterschool Settings

    Science.gov (United States)

    Mahoney, Joseph L.

    2014-01-01

    Although behavioral management is one of the most challenging aspects of working in an afterschool setting, staff do not typically receive formal training in evidence-based approaches to handling children's behavior problems. Common approaches to behavioral management such as punishment or time-out are temporary solutions because they do not…

  15. Gene set analysis for GWAS

    DEFF Research Database (Denmark)

    Debrabant, Birgit; Soerensen, Mette

    2014-01-01

    Abstract We discuss the use of modified Kolmogorov-Smirnov (KS) statistics in the context of gene set analysis and review corresponding null and alternative hypotheses. Especially, we show that, when enhancing the impact of highly significant genes in the calculation of the test statistic, the co...

  16. Blocking sets in Desarguesian planes

    NARCIS (Netherlands)

    Blokhuis, A.; Miklós, D.; Sós, V.T.; Szönyi, T.

    1996-01-01

    We survey recent results concerning the size of blocking sets in desarguesian projective and affine planes, and implications of these results and the technique to prove them, to related problemis, such as the size of maximal partial spreads, small complete arcs, small strong representative systems

  17. Dynamic elastic-plastic behaviour of a frame including coupled bending and torsion

    International Nuclear Information System (INIS)

    Messmer, S.; Sayir, M.

    1989-01-01

    The full time response of a space frame under impact loading perpendicular to the frame plane is discussed. Theoretical solutions and experimental results are presented and compared. A space frame clamped at its two ends is loaded by a 0.22 lead bullet that hits a mass in the middle of the transversal beam of the frame. The loading time is about 40 to 60 μs and the resulting linear momentum of the impact in the experiment is 0.5 to 1 N s. The time response of this frame can be divided in four phases where different physical effects are dominant: (a) The loading phase where elastic wave motion dominates the time response. Because of the high impact forces, plastic deformation occurs in the vicinity of the mass and must be included in a theoretical model. The influence of reflections at the corners on the time response is shown in theory and experiment. (b) The evolution phase. Within this phase, a plastic collapse mechanism develops. Most of this phase is dominated by elastic deformation but local plastic deformations beside the mass are also present. Because many reflections at corners, clamps and the mass occur within this phase, a modal analysis method is used to predict time histories. (c) The plastic phase with plastic zones at the clamps. The phase sets in after the bending wave reaches the clamps. It is characterized by plastic deformation near the clamps and elastic deformation of the other parts of the frame. We used a modal analysis including plastic 'modes' to get accurate results. (d) The elastic vibration phase

  18. Photoelectrochemical cell including Ga(Sb.sub.x)N.sub.1-x semiconductor electrode

    Science.gov (United States)

    Menon, Madhu; Sheetz, Michael; Sunkara, Mahendra Kumar; Pendyala, Chandrashekhar; Sunkara, Swathi; Jasinski, Jacek B.

    2017-09-05

    The composition of matter comprising Ga(Sb.sub.x)N.sub.1-x where x=0.01 to 0.06 is characterized by a band gap between 2.4 and 1.7 eV. A semiconductor device includes a semiconductor layer of that composition. A photoelectric cell includes that semiconductor device.

  19. Electrolyte solutions including a phosphoranimine compound, and energy storage devices including same

    Science.gov (United States)

    Klaehn, John R.; Dufek, Eric J.; Rollins, Harry W.; Harrup, Mason K.; Gering, Kevin L.

    2017-09-12

    An electrolyte solution comprising at least one phosphoranimine compound and a metal salt. The at least one phosphoranimine compound comprises a compound of the chemical structure ##STR00001## where X is an organosilyl group or a tert-butyl group and each of R.sup.1, R.sup.2, and R.sup.3 is independently selected from the group consisting of an alkyl group, an aryl group, an alkoxy group, or an aryloxy group. An energy storage device including the electrolyte solution is also disclosed.

  20. Identification of astrocytoma associated genes including cell surface markers

    International Nuclear Information System (INIS)

    Boon, Kathy; Edwards, Jennifer B; Eberhart, Charles G; Riggins, Gregory J

    2004-01-01

    Despite intense effort the treatment options for the invasive astrocytic tumors are still limited to surgery and radiation therapy, with chemotherapy showing little or no increase in survival. The generation of Serial Analysis of Gene Expression (SAGE) profiles is expected to aid in the identification of astrocytoma-associated genes and highly expressed cell surface genes as molecular therapeutic targets. SAGE tag counts can be easily added to public expression databases and quickly disseminated to research efforts worldwide. We generated and analyzed the SAGE transcription profiles of 25 primary grade II, III and IV astrocytomas [1]. These profiles were produced as part of the Cancer Genome Anatomy Project's SAGE Genie [2], and were used in an in silico search for candidate therapeutic targets by comparing astrocytoma to normal brain transcription. Real-time PCR and immunohistochemistry were used for the validation of selected candidate target genes in 2 independent sets of primary tumors. A restricted set of tumor-associated genes was identified for each grade that included genes not previously associated with astrocytomas (e.g. VCAM1, SMOC1, and thymidylate synthetase), with a high percentage of cell surface genes. Two genes with available antibodies, Aquaporin 1 and Topoisomerase 2A, showed protein expression consistent with transcript level predictions. This survey of transcription in malignant and normal brain tissues reveals a small subset of human genes that are activated in malignant astrocytomas. In addition to providing insights into pathway biology, we have revealed and quantified expression for a significant portion of cell surface and extra-cellular astrocytoma genes

  1. Final Hanford Site Transuranic (TRU) Waste Characterization QA Project Plan

    International Nuclear Information System (INIS)

    GREAGER, T.M.

    2000-01-01

    The Quality Assurance Project Plan (QAPjP) has been prepared for waste characterization activities to be conducted by the Transuranic (TRU) Project at the Hanford Site to meet requirements set forth in the Waste Isolation Pilot Plan (WIPP) Hazardous Waste Facility Permit, 4890139088-TSDF, Attachment B, including Attachments B1 through B6 (WAP) (DOE, 1999a). The QAPjP describes the waste characterization requirements and includes test methods, details of planned waste sampling and analysis, and a description of the waste characterization and verification process. In addition, the QAPjP includes a description of the quality assurance/quality control (QA/QC) requirements for the waste characterization program. Before TRU waste is shipped to the WIPP site by the TRU Project, all applicable requirements of the QAPjP shall be implemented. Additional requirements necessary for transportation to waste disposal at WIPP can be found in the ''Quality Assurance Program Document'' (DOE 1999b) and HNF-2600, ''Hanford Site Transuranic Waste Certification Plan.'' TRU mixed waste contains both TRU radioactive and hazardous components, as defined in the WLPP-WAP. The waste is designated and separately packaged as either contact-handled (CH) or remote-handled (RH), based on the radiological dose rate at the surface of the waste container. RH TRU wastes are not currently shipped to the WIPP facility

  2. The Effect of Distributed Practice in Undergraduate Statistics Homework Sets: A Randomized Trial

    Science.gov (United States)

    Crissinger, Bryan R.

    2015-01-01

    Most homework sets in statistics courses are constructed so that students concentrate or "mass" their practice on a certain topic in one problem set. Distributed practice homework sets include review problems in each set so that practice on a topic is distributed across problem sets. There is a body of research that points to the…

  3. Setting research priorities by applying the combined approach matrix.

    Science.gov (United States)

    Ghaffar, Abdul

    2009-04-01

    Priority setting in health research is a dynamic process. Different organizations and institutes have been working in the field of research priority setting for many years. In 1999 the Global Forum for Health Research presented a research priority setting tool called the Combined Approach Matrix or CAM. Since its development, the CAM has been successfully applied to set research priorities for diseases, conditions and programmes at global, regional and national levels. This paper briefly explains the CAM methodology and how it could be applied in different settings, giving examples and describing challenges encountered in the process of setting research priorities and providing recommendations for further work in this field. The construct and design of the CAM is explained along with different steps needed, including planning and organization of a priority-setting exercise and how it could be applied in different settings. The application of the CAM are described by using three examples. The first concerns setting research priorities for a global programme, the second describes application at the country level and the third setting research priorities for diseases. Effective application of the CAM in different and diverse environments proves its utility as a tool for setting research priorities. Potential challenges encountered in the process of research priority setting are discussed and some recommendations for further work in this field are provided.

  4. Annotation-based feature extraction from sets of SBML models.

    Science.gov (United States)

    Alm, Rebekka; Waltemath, Dagmar; Wolfien, Markus; Wolkenhauer, Olaf; Henkel, Ron

    2015-01-01

    Model repositories such as BioModels Database provide computational models of biological systems for the scientific community. These models contain rich semantic annotations that link model entities to concepts in well-established bio-ontologies such as Gene Ontology. Consequently, thematically similar models are likely to share similar annotations. Based on this assumption, we argue that semantic annotations are a suitable tool to characterize sets of models. These characteristics improve model classification, allow to identify additional features for model retrieval tasks, and enable the comparison of sets of models. In this paper we discuss four methods for annotation-based feature extraction from model sets. We tested all methods on sets of models in SBML format which were composed from BioModels Database. To characterize each of these sets, we analyzed and extracted concepts from three frequently used ontologies, namely Gene Ontology, ChEBI and SBO. We find that three out of the methods are suitable to determine characteristic features for arbitrary sets of models: The selected features vary depending on the underlying model set, and they are also specific to the chosen model set. We show that the identified features map on concepts that are higher up in the hierarchy of the ontologies than the concepts used for model annotations. Our analysis also reveals that the information content of concepts in ontologies and their usage for model annotation do not correlate. Annotation-based feature extraction enables the comparison of model sets, as opposed to existing methods for model-to-keyword comparison, or model-to-model comparison.

  5. Difference sets connecting algebra, combinatorics, and geometry

    CERN Document Server

    Moore, Emily H

    2013-01-01

    Difference sets belong both to group theory and to combinatorics. Studying them requires tools from geometry, number theory, and representation theory. This book lays a foundation for these topics, including a primer on representations and characters of finite groups. It makes the research literature on difference sets accessible to students who have studied linear algebra and abstract algebra, and it prepares them to do their own research. This text is suitable for an undergraduate capstone course, since it illuminates the many links among topics that the students have already studied. To this end, almost every chapter ends with a coda highlighting the main ideas and emphasizing mathematical connections. This book can also be used for self-study by anyone interested in these connections and concrete examples. An abundance of exercises, varying from straightforward to challenging, invites the reader to solve puzzles, construct proofs, and investigate problems--by hand or on a computer. Hints and solutions are...

  6. Option Panels in Pure-Jump Settings

    DEFF Research Database (Denmark)

    Andersen, Torben Gustav; Fusari, Nicola; Todorov, Viktor

    We develop parametric inference procedures for large panels of noisy option data in the setting where the underlying process is of pure-jump type, i.e., evolve only through a sequence of jumps. The panel consists of options written on the underlying asset with a (different) set of strikes...... specification for the risk-neutral asset return dynamics, the option prices are nonlinear functions of a time-invariant parameter vector and a time-varying latent state vector (or factors). Furthermore, no-arbitrage restrictions impose a direct link between some of the quantities that may be identified from...... the return and option data. These include the so-called jump activity index as well as the time-varying jump intensity. We propose penalized least squares estimation in which we minimize L_2 distance between observed and model-implied options and further penalize for the deviation of model-implied quantities...

  7. Leadership and priority setting: the perspective of hospital CEOs.

    Science.gov (United States)

    Reeleder, David; Goel, Vivek; Singer, Peter A; Martin, Douglas K

    2006-11-01

    The role of leadership in health care priority setting remains largely unexplored. While the management leadership literature has grown rapidly, the growing literature on priority setting in health care has looked in other directions to improve priority setting practices--to health economics and ethical approaches. Consequently, potential for improvement in hospital priority setting practices may be overlooked. A qualitative study involving interviews with 46 Ontario hospital CEOs was done to describe the role of leadership in priority setting through the perspective of hospital leaders. For the first time, we report a framework of leadership domains including vision, alignment, relationships, values and process to facilitate priority setting practices in health services' organizations. We believe this fledgling framework forms the basis for the sharing of good leadership practices for health reform. It also provides a leadership guide for decision makers to improve the quality of their leadership, and in so doing, we believe, the fairness of their priority setting.

  8. Hypergraphs combinatorics of finite sets

    CERN Document Server

    Berge, C

    1989-01-01

    Graph Theory has proved to be an extremely useful tool for solving combinatorial problems in such diverse areas as Geometry, Algebra, Number Theory, Topology, Operations Research and Optimization. It is natural to attempt to generalise the concept of a graph, in order to attack additional combinatorial problems. The idea of looking at a family of sets from this standpoint took shape around 1960. In regarding each set as a ``generalised edge'' and in calling the family itself a ``hypergraph'', the initial idea was to try to extend certain classical results of Graph Theory such as the theorems of Turán and König. It was noticed that this generalisation often led to simplification; moreover, one single statement, sometimes remarkably simple, could unify several theorems on graphs. This book presents what seems to be the most significant work on hypergraphs.

  9. Abstraction by Set-Membership

    DEFF Research Database (Denmark)

    Mödersheim, Sebastian Alexander

    2010-01-01

    The abstraction and over-approximation of protocols and web services by a set of Horn clauses is a very successful method in practice. It has however limitations for protocols and web services that are based on databases of keys, contracts, or even access rights, where revocation is possible, so...... that the set of true facts does not monotonically grow with the transitions. We extend the scope of these over-approximation methods by defining a new way of abstraction that can handle such databases, and we formally prove that the abstraction is sound. We realize a translator from a convenient specification...... language to standard Horn clauses and use the verifier ProVerif and the theorem prover SPASS to solve them. We show by a number of examples that this approach is practically feasible for wide variety of verification problems of security protocols and web services....

  10. First-Class Object Sets

    DEFF Research Database (Denmark)

    Ernst, Erik

    2009-01-01

    Typically, an object is a monolithic entity with a fixed interface.  To increase flexibility in this area, this paper presents first-class object sets as a language construct.  An object set offers an interface which is a disjoint union of the interfaces of its member objects.  It may also be use...... to a mainstream virtual machine in order to improve on the support for family polymorphism.  The approach is made precise by means of a small calculus, and the soundness of its type system has been shown by a mechanically checked proof in Coq....

  11. Harm reduction principles for healthcare settings

    Directory of Open Access Journals (Sweden)

    Mary Hawk

    2017-10-01

    Full Text Available Abstract Background Harm reduction refers to interventions aimed at reducing the negative effects of health behaviors without necessarily extinguishing the problematic health behaviors completely. The vast majority of the harm reduction literature focuses on the harms of drug use and on specific harm reduction strategies, such as syringe exchange, rather than on the harm reduction philosophy as a whole. Given that a harm reduction approach can address other risk behaviors that often occur alongside drug use and that harm reduction principles have been applied to harms such as sex work, eating disorders, and tobacco use, a natural evolution of the harm reduction philosophy is to extend it to other health risk behaviors and to a broader healthcare audience. Methods Building on the extant literature, we used data from in-depth qualitative interviews with 23 patients and 17 staff members from an HIV clinic in the USA to describe harm reduction principles for use in healthcare settings. Results We defined six principles of harm reduction and generalized them for use in healthcare settings with patients beyond those who use illicit substances. The principles include humanism, pragmatism, individualism, autonomy, incrementalism, and accountability without termination. For each of these principles, we present a definition, a description of how healthcare providers can deliver interventions informed by the principle, and examples of how each principle may be applied in the healthcare setting. Conclusion This paper is one of the firsts to provide a comprehensive set of principles for universal harm reduction as a conceptual approach for healthcare provision. Applying harm reduction principles in healthcare settings may improve clinical care outcomes given that the quality of the provider-patient relationship is known to impact health outcomes and treatment adherence. Harm reduction can be a universal precaution applied to all individuals regardless of

  12. Borderline Personality in the Medical Setting

    Science.gov (United States)

    Sansone, Lori A.

    2015-01-01

    Objective: Individuals with borderline personality disorder in mental health settings tend to present with relationship difficulties, mood instability/dysphoria, and overt self-harm behavior. In contrast, it appears that individuals with borderline personality disorder in medical settings manifest physical symptoms that are medically difficult to substantiate. Through a review of the literature, we examine 2 symptom manifestations among patients with borderline personality in primary care and general medical settings—namely pain sensitivity and multiple somatic complaints. In addition to reviewing the research of others, we also highlight our own investigations into these 2 areas. Data Sources: We conducted a literature search of the PubMed database and a previous version of the PsycINFO search engine (no restrictions). Search terms included borderline personality, borderline personality disorder, personality disorders; chronic pain, pain, pain syndromes; and somatization disorder, Briquet’s syndrome, somatic preoccupation, somatic. Study Selection: Published articles related to borderline personality, pain and somatic symptoms (ie, somatization disorder, somatic preoccupation) were examined. Results: According to our review, the literature indicates higher-than-expected rates of borderline personality disorder among patients in primary care and general medical settings who present with chronic pain conditions and/or somatic preoccupation. Conclusions: Unlike patients with borderline personality disorder in mental health settings, who tend to present with relationship difficulties, mood instability/dysphoria, and overt self-harm behavior, patients with borderline personality disorder in primary care settings tend to present with unsubstantiated chronic pain of various types as well as somatic preoccupation. PMID:26644960

  13. Harm reduction principles for healthcare settings.

    Science.gov (United States)

    Hawk, Mary; Coulter, Robert W S; Egan, James E; Fisk, Stuart; Reuel Friedman, M; Tula, Monique; Kinsky, Suzanne

    2017-10-24

    Harm reduction refers to interventions aimed at reducing the negative effects of health behaviors without necessarily extinguishing the problematic health behaviors completely. The vast majority of the harm reduction literature focuses on the harms of drug use and on specific harm reduction strategies, such as syringe exchange, rather than on the harm reduction philosophy as a whole. Given that a harm reduction approach can address other risk behaviors that often occur alongside drug use and that harm reduction principles have been applied to harms such as sex work, eating disorders, and tobacco use, a natural evolution of the harm reduction philosophy is to extend it to other health risk behaviors and to a broader healthcare audience. Building on the extant literature, we used data from in-depth qualitative interviews with 23 patients and 17 staff members from an HIV clinic in the USA to describe harm reduction principles for use in healthcare settings. We defined six principles of harm reduction and generalized them for use in healthcare settings with patients beyond those who use illicit substances. The principles include humanism, pragmatism, individualism, autonomy, incrementalism, and accountability without termination. For each of these principles, we present a definition, a description of how healthcare providers can deliver interventions informed by the principle, and examples of how each principle may be applied in the healthcare setting. This paper is one of the firsts to provide a comprehensive set of principles for universal harm reduction as a conceptual approach for healthcare provision. Applying harm reduction principles in healthcare settings may improve clinical care outcomes given that the quality of the provider-patient relationship is known to impact health outcomes and treatment adherence. Harm reduction can be a universal precaution applied to all individuals regardless of their disclosure of negative health behaviors, given that health

  14. Optics education in an optometric setting

    Science.gov (United States)

    Putnam, Nicole M.

    2017-08-01

    The first year optics curriculum at the Arizona College of Optometry aims to provide students with an understanding of geometrical, physical, and visual optics principals that will be the foundation of their clinical understanding of the optics of the eye and its correction in advanced courses such as ophthalmic optics and contact lenses. Although the optics of the eye are a fantastic model to use in optics education, the clinical applications may not become apparent until later in the course of study. Successful strategies are needed to engage students and facilitate the understanding of optical principals and the growth of process skills including problem solving, analysis, and critical thinking that will help in their future as health care providers. These include the implementation of ophthalmic applications as early as possible, encouragement of group work including open office hours, and the use of video problem set solutions to supplement traditional static solutions.

  15. Compositional models for credal sets

    Czech Academy of Sciences Publication Activity Database

    Vejnarová, Jiřina

    2017-01-01

    Roč. 90, č. 1 (2017), s. 359-373 ISSN 0888-613X R&D Projects: GA ČR(CZ) GA16-12010S Institutional support: RVO:67985556 Keywords : Imprecise probabilities * Credal sets * Multidimensional models * Conditional independence Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 2.845, year: 2016 http://library.utia.cas.cz/separaty/2017/MTR/vejnarova-0483288.pdf

  16. The Value of Value Sets

    DEFF Research Database (Denmark)

    Sløk-Madsen, Stefan Kirkegaard; Christensen, Jesper

    The world over classrooms in business schools are being taught that corporate values can impact performance. The argument is typically that culture matter more than strategy plans and culture can be influenced and indeed changed by a shared corporate value set. While the claim seems intuitively a...... a unique contribution to the effects of investment in shared company values, and to whether agent rationality can be fundamentally changed by committed organizational efforts....

  17. Some remarks on good sets

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    A subset S of is said to be full, if S is a maximal good set in 1S × 2S ืทททื nS. ([3], p. 183). Two points .... assume there is a p for which |np|= |mp|. Then. ∑k j=1 nj xj = 0 ..... M G Nadkarni for suggesting the problems and for encouragement and ...

  18. Scale setting in lattice QCD

    International Nuclear Information System (INIS)

    Sommer, Rainer

    2014-02-01

    The principles of scale setting in lattice QCD as well as the advantages and disadvantages of various commonly used scales are discussed. After listing criteria for good scales, I concentrate on the main presently used ones with an emphasis on scales derived from the Yang-Mills gradient flow. For these I discuss discretisation errors, statistical precision and mass effects. A short review on numerical results also brings me to an unpleasant disagreement which remains to be explained.

  19. Set Reordering for Paletted Data

    KAUST Repository

    Schneider, Jens

    2011-03-01

    We present a novel method to recycle bits of paletted data sets. We exploit that the codebook of such data can be reordered without affecting the content. Enumerating all possible permutations of N codebook entries yields an additional O(N log2 N) bits that can be used without storage overhed for the losless encoding of a limited amount of tags, meta-information, or part of the actual data. © 2011 IEEE.

  20. Exemestane in the prevention setting

    OpenAIRE

    Litton, Jennifer Keating; Bevers, Therese B.; Arun, Banu K.

    2012-01-01

    Aromatase inhibitors are well-established therapies in the neoadjuvant, adjuvant and metastatic settings for breast cancer. In adjuvant trials, this class of drugs has shown preventative properties by decreasing the rate of contralateral breast cancer. Recently, the National Cancer Institute of Canada Clinical Trials Group MAP.3 study evaluated exemestane as a breast cancer prevention agent for women with specified higher risks of developing breast cancer. We review the history of exemestane ...

  1. Scale setting in lattice QCD

    Energy Technology Data Exchange (ETDEWEB)

    Sommer, Rainer [DESY, Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

    2014-02-15

    The principles of scale setting in lattice QCD as well as the advantages and disadvantages of various commonly used scales are discussed. After listing criteria for good scales, I concentrate on the main presently used ones with an emphasis on scales derived from the Yang-Mills gradient flow. For these I discuss discretisation errors, statistical precision and mass effects. A short review on numerical results also brings me to an unpleasant disagreement which remains to be explained.

  2. Setting priorities for safeguards upgrades

    International Nuclear Information System (INIS)

    Al-Ayat, R.A.; Judd, B.R.; Patenaude, C.J.; Sicherman, A.

    1987-01-01

    This paper describes an analytic approach and a computer program for setting priorities among safeguards upgrades. The approach provides safeguards decision makers with a systematic method for allocating their limited upgrade resources. The priorities are set based on the upgrades cost and their contribution to safeguards effectiveness. Safeguards effectiveness is measured by the probability of defeat for a spectrum of potential insider and outsider adversaries. The computer program, MI$ER, can be used alone or as a companion to ET and SAVI, programs designed to evaluate safeguards effectiveness against insider and outsider threats, respectively. Setting the priority required judgments about the relative importance (threat likelihoods and consequences) of insider and outsider threats. Although these judgments are inherently subjective, MI$ER can analyze the sensitivity of the upgrade priorities to these weights and determine whether or not they are critical to the priority ranking. MI$ER produces tabular and graphical results for comparing benefits and identifying the most cost-effective upgrades for a given expenditure. This framework provides decision makers with an explicit and consistent analysis to support their upgrades decisions and to allocate the safeguards resources in a cost-effective manner

  3. A course on Borel sets

    CERN Document Server

    Srivastava, S M

    1998-01-01

    The roots of Borel sets go back to the work of Baire [8]. He was trying to come to grips with the abstract notion of a function introduced by Dirich­ let and Riemann. According to them, a function was to be an arbitrary correspondence between objects without giving any method or procedure by which the correspondence could be established. Since all the specific functions that one studied were determined by simple analytic expressions, Baire delineated those functions that can be constructed starting from con­ tinuous functions and iterating the operation 0/ pointwise limit on a se­ quence 0/ functions. These functions are now known as Baire functions. Lebesgue [65] and Borel [19] continued this work. In [19], Borel sets were defined for the first time. In his paper, Lebesgue made a systematic study of Baire functions and introduced many tools and techniques that are used even today. Among other results, he showed that Borel functions coincide with Baire functions. The study of Borel sets got an impetus from...

  4. Introduction to axiomatic set theory

    CERN Document Server

    Takeuti, Gaisi

    1971-01-01

    In 1963, the first author introduced a course in set theory at the Uni­ versity of Illinois whose main objectives were to cover G6del's work on the consistency of the axiom of choice (AC) and the generalized con­ tinuum hypothesis (GCH), and Cohen's work on the independence of AC and the GCH. Notes taken in 1963 by the second author were the taught by him in 1966, revised extensively, and are presented here as an introduction to axiomatic set theory. Texts in set theory frequently develop the subject rapidly moving from key result to key result and suppressing many details. Advocates of the fast development claim at least two advantages. First, key results are highlighted, and second, the student who wishes to master the sub­ ject is compelled to develop the details on his own. However, an in­ structor using a "fast development" text must devote much class time to assisting his students in their efforts to bridge gaps in the text. We have chosen instead a development that is quite detailed and complete. F...

  5. Goal setting with mothers in child development services.

    Science.gov (United States)

    Forsingdal, S; St John, W; Miller, V; Harvey, A; Wearne, P

    2014-07-01

    The aim of this grounded theory study was to explore mothers' perspectives of the processes of collaborative goal setting in multidisciplinary child development services involving follow-up home therapy. Semi-structured interviews were conducted in South East Queensland, Australia with 14 mothers of children aged 3-6 years who were accessing multidisciplinary child development services. Interviews were focussed around the process of goal setting. A grounded theory of Maternal Roles in Goal Setting (The M-RIGS Model) was developed from analysis of data. Mothers assumed Dependent, Active Participator and Collaborator roles when engaging with the therapist in goal-setting processes. These roles were characterized by the mother's level of dependence on the therapist and insight into their child's needs and therapy processes. Goal Factors, Parent Factors and Therapist Factors influenced and added complexity to the goal-setting process. The M-RIGS Model highlights that mothers take on a range of roles in the goal-setting process. Although family-centred practice encourages negotiation and collaborative goal setting, parents may not always be ready to take on highly collaborative roles. Better understanding of parent roles, goal-setting processes and influencing factors will inform better engagement with families accessing multidisciplinary child development services. © 2013 John Wiley & Sons Ltd.

  6. Global anthropogenic emissions of particulate matter including black carbon

    Science.gov (United States)

    Klimont, Zbigniew; Kupiainen, Kaarle; Heyes, Chris; Purohit, Pallav; Cofala, Janusz; Rafaj, Peter; Borken-Kleefeld, Jens; Schöpp, Wolfgang

    2017-07-01

    was the most important sector, contributing about 60 % for BC and OC, 45 % for PM2. 5, and less than 40 % for PM10, where large combustion sources and industrial processes are equally important. Global anthropogenic emissions of BC were estimated at about 6.6 and 7.2 Tg in 2000 and 2010, respectively, and represent about 15 % of PM2. 5 but for some sources reach nearly 50 %, i.e. for the transport sector. Our global BC numbers are higher than previously published owing primarily to the inclusion of new sources. This PM estimate fills the gap in emission data and emission source characterization required in air quality and climate modelling studies and health impact assessments at a regional and global level, as it includes both carbonaceous and non-carbonaceous constituents of primary particulate matter emissions. The developed emission dataset has been used in several regional and global atmospheric transport and climate model simulations within the ECLIPSE (Evaluating the Climate and Air Quality Impacts of Short-Lived Pollutants) project and beyond, serves better parameterization of the global integrated assessment models with respect to representation of black carbon and organic carbon emissions, and built a basis for recently published global particulate number estimates.

  7. Global anthropogenic emissions of particulate matter including black carbon

    Directory of Open Access Journals (Sweden)

    Z. Klimont

    2017-07-01

    anthropogenic total, and residential combustion was the most important sector, contributing about 60 % for BC and OC, 45 % for PM2. 5, and less than 40 % for PM10, where large combustion sources and industrial processes are equally important. Global anthropogenic emissions of BC were estimated at about 6.6 and 7.2 Tg in 2000 and 2010, respectively, and represent about 15 % of PM2. 5 but for some sources reach nearly 50 %, i.e. for the transport sector. Our global BC numbers are higher than previously published owing primarily to the inclusion of new sources. This PM estimate fills the gap in emission data and emission source characterization required in air quality and climate modelling studies and health impact assessments at a regional and global level, as it includes both carbonaceous and non-carbonaceous constituents of primary particulate matter emissions. The developed emission dataset has been used in several regional and global atmospheric transport and climate model simulations within the ECLIPSE (Evaluating the Climate and Air Quality Impacts of Short-Lived Pollutants project and beyond, serves better parameterization of the global integrated assessment models with respect to representation of black carbon and organic carbon emissions, and built a basis for recently published global particulate number estimates.

  8. Greenhouse Effect Detection Experiment (GEDEX). Selected data sets

    Science.gov (United States)

    Olsen, Lola M.; Warnock, Archibald, III

    1992-01-01

    This CD-ROM contains selected data sets compiled by the participants of the Greenhouse Effect Detection Experiment (GEDEX) workshop on atmospheric temperature. The data sets include surface, upper air, and/or satellite-derived measurements of temperature, solar irradiance, clouds, greenhouse gases, fluxes, albedo, aerosols, ozone, and water vapor, along with Southern Oscillation Indices and Quasi-Biennial Oscillation statistics.

  9. Szegö's theorem on Parreau-Widom sets

    DEFF Research Database (Denmark)

    Christiansen, Jacob Stordal

    2012-01-01

    In this paper, we generalize Szego's theorem for orthogonal polynomials on the real line to infinite gap sets of Parreau–Widom type. This notion includes Cantor sets of positive measure. The Szego condition involves the equilibrium measure which in turn is absolutely continuous. Our approach builds...

  10. Setting the Record Straight. The Truth About Fad Diets.

    Science.gov (United States)

    Wheat Foods Council, Parker, CO.

    The Setting the Record Straight information packet presents facts to set the record straight about nutrition and debunk fad diets. The kit features materials designed to communicate the importance of balanced eating. Materials include: a time line of fad diets; four reproducible fad diet book review handouts that show the misleading claims rampant…

  11. Deliberate Practice of Creativity Training Set Series - A Creativity Training Material for Education (work in progress)

    DEFF Research Database (Denmark)

    Byrge, Christian

    2018-01-01

    Five training sets including 450 unique thinking direction cards and 120 exercise cards. Designed for Educational Purposes.......Five training sets including 450 unique thinking direction cards and 120 exercise cards. Designed for Educational Purposes....

  12. System Administrator for LCS Development Sets

    Science.gov (United States)

    Garcia, Aaron

    2013-01-01

    The Spaceport Command and Control System Project is creating a Checkout and Control System that will eventually launch the next generation of vehicles from Kennedy Space Center. KSC has a large set of Development and Operational equipment already deployed in several facilities, including the Launch Control Center, which requires support. The position of System Administrator will complete tasks across multiple platforms (Linux/Windows), many of them virtual. The Hardware Branch of the Control and Data Systems Division at the Kennedy Space Center uses system administrators for a variety of tasks. The position of system administrator comes with many responsibilities which include maintaining computer systems, repair or set up hardware, install software, create backups and recover drive images are a sample of jobs which one must complete. Other duties may include working with clients in person or over the phone and resolving their computer system needs. Training is a major part of learning how an organization functions and operates. Taking that into consideration, NASA is no exception. Training on how to better protect the NASA computer infrastructure will be a topic to learn, followed by NASA work polices. Attending meetings and discussing progress will be expected. A system administrator will have an account with root access. Root access gives a user full access to a computer system and or network. System admins can remove critical system files and recover files using a tape backup. Problem solving will be an important skill to develop in order to complete the many tasks.

  13. Internet interventions for chronic pain including headache: A systematic review

    Directory of Open Access Journals (Sweden)

    Monica Buhrman

    2016-05-01

    Full Text Available Chronic pain is a major health problem and behavioral based treatments have been shown to be effective. However, the availability of these kinds of treatments is scarce and internet-based treatments have been shown to be promising in this area. The objective of the present systematic review is to evaluate internet-based interventions for persons with chronic pain. The specific aims are to do an updated review with a broad inclusion of different chronic pain diagnoses and to assess disability and pain and also measures of catastrophizing, depression and anxiety. A systematic search identified 891 studies and 22 trials were selected as eligible for review. Two of the selected trials included children/youth and five included individuals with chronic headache and/or migraine. The most frequently measured domain reflected in the primary outcomes was interference/disability, followed by catastrophizing. Result across the studies showed a number of beneficial effects. Twelve trials reported significant effects on disability/interference outcomes and pain intensity. Positive effects were also found on psychological variable such as catastrophizing, depression and anxiety. Several studies (n = 12 were assessed to have an unclear level of risk bias. The attrition levels ranged from 4% to 54% where the headache trials had the highest drop-out levels. However, findings suggest that internet-based treatments based on cognitive behavioural therapy (CBT are efficacious measured with different outcome variables. Results are in line with trials in clinical settings. Meta-analytic statistics were calculated for interference/disability, pain intensity, catastrophizing and mood ratings. Results showed that the effect size for interference/disability was Hedge's g = −0.39, for pain intensity Hedge's g = −0.33, for catastrophizing Hedge's g = −0.49 and for mood variables (depression Hedge's g = −0.26.

  14. Extending Vulnerability Assessment to Include Life Stages Considerations.

    Science.gov (United States)

    Hodgson, Emma E; Essington, Timothy E; Kaplan, Isaac C

    2016-01-01

    Species are experiencing a suite of novel stressors from anthropogenic activities that have impacts at multiple scales. Vulnerability assessment is one tool to evaluate the likely impacts that these stressors pose to species so that high-vulnerability cases can be identified and prioritized for monitoring, protection, or mitigation. Commonly used semi-quantitative methods lack a framework to explicitly account for differences in exposure to stressors and organism responses across life stages. Here we propose a modification to commonly used spatial vulnerability assessment methods that includes such an approach, using ocean acidification in the California Current as an illustrative case study. Life stage considerations were included by assessing vulnerability of each life stage to ocean acidification and were used to estimate population vulnerability in two ways. We set population vulnerability equal to: (1) the maximum stage vulnerability and (2) a weighted mean across all stages, with weights calculated using Lefkovitch matrix models. Vulnerability was found to vary across life stages for the six species explored in this case study: two krill-Euphausia pacifica and Thysanoessa spinifera, pteropod-Limacina helicina, pink shrimp-Pandalus jordani, Dungeness crab-Metacarcinus magister and Pacific hake-Merluccius productus. The maximum vulnerability estimates ranged from larval to subadult and adult stages with no consistent stage having maximum vulnerability across species. Similarly, integrated vulnerability metrics varied greatly across species. A comparison showed that some species had vulnerabilities that were similar between the two metrics, while other species' vulnerabilities varied substantially between the two metrics. These differences primarily resulted from cases where the most vulnerable stage had a low relative weight. We compare these methods and explore circumstances where each method may be appropriate.

  15. Accurate SHAPE-directed RNA secondary structure modeling, including pseudoknots.

    Science.gov (United States)

    Hajdin, Christine E; Bellaousov, Stanislav; Huggins, Wayne; Leonard, Christopher W; Mathews, David H; Weeks, Kevin M

    2013-04-02

    A pseudoknot forms in an RNA when nucleotides in a loop pair with a region outside the helices that close the loop. Pseudoknots occur relatively rarely in RNA but are highly overrepresented in functionally critical motifs in large catalytic RNAs, in riboswitches, and in regulatory elements of viruses. Pseudoknots are usually excluded from RNA structure prediction algorithms. When included, these pairings are difficult to model accurately, especially in large RNAs, because allowing this structure dramatically increases the number of possible incorrect folds and because it is difficult to search the fold space for an optimal structure. We have developed a concise secondary structure modeling approach that combines SHAPE (selective 2'-hydroxyl acylation analyzed by primer extension) experimental chemical probing information and a simple, but robust, energy model for the entropic cost of single pseudoknot formation. Structures are predicted with iterative refinement, using a dynamic programming algorithm. This melded experimental and thermodynamic energy function predicted the secondary structures and the pseudoknots for a set of 21 challenging RNAs of known structure ranging in size from 34 to 530 nt. On average, 93% of known base pairs were predicted, and all pseudoknots in well-folded RNAs were identified.

  16. Pediatric pancreas transplantation, including total pancreatectomy with islet autotransplantation.

    Science.gov (United States)

    Bondoc, Alexander J; Abu-El-Haija, Maisam; Nathan, Jaimie D

    2017-08-01

    Unlike other solid-organ transplants, whole pancreas transplantation in children is relatively rare, and it occurs more frequently in the context of multivisceral or composite organ transplantation. Because children only infrequently suffer severe sequelae of type 1 diabetes mellitus, pancreas transplantation is rarely indicated in the pediatric population. More commonly, pediatric pancreas transplant occurs in the setting of incapacitating acute recurrent or chronic pancreatitis, specifically islet autotransplantation after total pancreatectomy. In this clinical scenario, total pancreatectomy removes the nidus of chronic pain and debilitation, while autologous islet transplantation aims to preserve endocrine function. The published experiences with pediatric total pancreatectomy with islet autotransplantation (TPIAT) in children has demonstrated excellent outcomes including liberation from chronic opioid use, as well as improved mental and physical quality of life with good glycemic control. Given the complexity of the operation, risk of postoperative complication, and long-term physiologic changes, appropriate patient selection and comprehensive multidisciplinary care teams are critical to ensuring optimal outcomes. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Pathological Fire Setting Behavior in Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Fatmagul Helvaci Celik

    2014-06-01

    Full Text Available Pathological fire setting behavior is characterized by various types of fire setting behavior that lasts at least 6 months. This behavior can be observed both during childhood and adolescence and it develops as a result of the complex interaction between individual, social and environmental factors. Sample population based studies show that fire setting behavior occurs in children and adolescents by 5-10%. The studies that have been conducted have yielded to various theories and findings concerning the mechanism of occurrence of pathological fire setting behavior, the factors that affect this behavior and the demographic, individual, family and environmental characteristics of the children and adolescents who engage in such behavior. The objectives of effective treatment strategies are reducing fire setting behavior as well as making significant changes in the causes underlying the psychopathology. Outpatient care is the preferred method. In addition, there are some inpatient treatment programs designed especially for young people who set fires. The two most common approaches in intervention concerning fire setting behavior are firefighting (fire service based training interventions and mental health based psycho-social interventions. Even though numerous studies have been conducted in the world concerning pathological fire setting behavior from the 19th century onwards, no epidemiological data or study on pathological fire setting behavior exists in Turkey. This seems to be the case in our country despite the fact that fire setting behavior at various degrees and even arson occurs in children and adolescents and results in material damage as well as serious injury and even death especially in the context of children who are pushed into crime. Our objective is to discuss pathological fire setting behavior in line with the literature on the subject, to increase the awareness of the fire service institutions and to shed light on further studies to

  18. Teaching in Overseas Military Settings.

    Science.gov (United States)

    McKinney, Fred

    1980-01-01

    Reveals strengths and weaknesses encountered by a psychology teacher involved in the overseas graduate counseling program for Ball State University. Problems included lack of proper teaching and counseling facilities, long teaching hours, and civilian teachers' ignorance of military protocol. Advantages included helping military personnel obtain a…

  19. Characterization of dielectric materials

    Energy Technology Data Exchange (ETDEWEB)

    King, Danny J.; Babinec, Susan; Hagans, Patrick L.; Maxey, Lonnie C.; Payzant, Edward A.; Daniel, Claus; Sabau, Adrian S.; Dinwiddie, Ralph B.; Armstrong, Beth L.; Howe, Jane Y.; Wood, III, David L.; Nembhard, Nicole S.

    2017-06-27

    A system and a method for characterizing a dielectric material are provided. The system and method generally include applying an excitation signal to electrodes on opposing sides of the dielectric material to evaluate a property of the dielectric material. The method can further include measuring the capacitive impedance across the dielectric material, and determining a variation in the capacitive impedance with respect to either or both of a time domain and a frequency domain. The measured property can include pore size and surface imperfections. The method can still further include modifying a processing parameter as the dielectric material is formed in response to the detected variations in the capacitive impedance, which can correspond to a non-uniformity in the dielectric material.

  20. English vocabulary set #1 interactive flashcards book

    CERN Document Server

    REA, The Editors of

    2013-01-01

    REA's Interactive Flashcard books represent a novel approach which combines the merits of flash cards with the ease of using a book. One side of each page includes questions to be answered, with space for writing in one's answers - a feature not usually found on flash cards. The flip side of the same page contains the correct answers, much as flash cards do. English Vocabulary (Set #1) is fully indexed making it easy to locate topics for study. Thanks to the book form, there is no need to look for and fish out appropriate questions from a box and put them back in the proper order, and the