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Sample records for inaccurate results due

  1. Methods for detecting and correcting inaccurate results in inductively coupled plasma-atomic emission spectrometry

    Science.gov (United States)

    Chan, George C. Y. [Bloomington, IN; Hieftje, Gary M [Bloomington, IN

    2010-08-03

    A method for detecting and correcting inaccurate results in inductively coupled plasma-atomic emission spectrometry (ICP-AES). ICP-AES analysis is performed across a plurality of selected locations in the plasma on an unknown sample, collecting the light intensity at one or more selected wavelengths of one or more sought-for analytes, creating a first dataset. The first dataset is then calibrated with a calibration dataset creating a calibrated first dataset curve. If the calibrated first dataset curve has a variability along the location within the plasma for a selected wavelength, errors are present. Plasma-related errors are then corrected by diluting the unknown sample and performing the same ICP-AES analysis on the diluted unknown sample creating a calibrated second dataset curve (accounting for the dilution) for the one or more sought-for analytes. The cross-over point of the calibrated dataset curves yields the corrected value (free from plasma related errors) for each sought-for analyte.

  2. Hypo- and hypernatremia results in inaccurate erythrocyte mean corpuscular volume measurement in vitro, when using Sysmex XE 2100

    DEFF Research Database (Denmark)

    Phillipsen, Jens Peter; Madsen, Kirsten Vikkelsø

    2015-01-01

    INTRODUCTION: Automated hematology analyzers dilute patient erythrocytes with an isoosmotic diluent before quantitating the erythrocyte mean cell volume (MCV). However, if patient plasma osmolality differs from the diluent, water will cross the erythrocytes membrane and establish a new equilibrium...... resulted in inaccurate MCV. The experimental results also revealed a strong correlation between P-Osmolality/P-Sodium and MCV inaccuracy (R2 = 0.70/0.85) similar to the theoretically calculated MCV inaccuracy. We suggest using mean cellular Hb (MCH) instead of MCV, mean corpuscular Hb concentration (MCHC...

  3. Reducing reliance on inaccurate information.

    Science.gov (United States)

    Rapp, David N; Hinze, Scott R; Kohlhepp, Kristine; Ryskin, Rachel A

    2014-01-01

    People learn from the texts that they read, but sometimes what they read is wrong. Previous research has demonstrated that individuals encode even obvious inaccuracies, at times relying on the misinformation to complete postreading tasks. In the present study, we investigated whether the influence of inaccurate information might be reduced by encouraging the retrieval of accurate knowledge. Participants read an extended text that contained both accurate and inaccurate assertions, after which they evaluated the validity of statements associated with those assertions. In general, participants made more mistakes in their evaluations of statements after having read inaccurate as compared to accurate assertions, offering evidence of the influence of misinformation. However, when participants were tasked with correcting inaccuracies during reading, their mistakes were substantially reduced. Encouraging the retrieval of accurate knowledge during reading can reduce the influence of misinformation. These findings are discussed with respect to the contributions of episodic traces and prior knowledge on learning, as well as to the conditions that support successful comprehension.

  4. Why 1D electrical resistivity techniques can result in inaccurate siting of boreholes in hard rock aquifers and why electrical resistivity tomography must be preferred: the example of Benin, West Africa

    Science.gov (United States)

    Alle, Iboukoun Christian; Descloitres, Marc; Vouillamoz, Jean-Michel; Yalo, Nicaise; Lawson, Fabrice Messan Amen; Adihou, Akonfa Consolas

    2018-03-01

    Hard rock aquifers are of particular importance for supplying people with drinking water in Africa and in the world. Although the common use of one-dimensional (1D) electrical resistivity techniques to locate drilling site, the failure rate of boreholes is usually high. For instance, about 40% of boreholes drilled in hard rock aquifers in Benin are unsuccessful. This study investigates why the current use of 1D techniques (e.g. electrical profiling and electrical sounding) can result in inaccurate siting of boreholes, and checks the interest and the limitations of the use of two-dimensional (2D) Electrical Resistivity Tomography (ERT). Geophysical numerical modeling and comprehensive 1D and 2D resistivity surveys were carried out in hard rock aquifers in Benin. The experiments carried out at 7 sites located in different hard rock groups confirmed the results of the numerical modeling: the current use of 1D techniques can frequently leads to inaccurate siting, and ERT better reveals hydrogeological targets such as thick weathered zone (e.g. stratiform fractured layer and preferential weathering associated with subvertical fractured zone). Moreover, a cost analysis demonstrates that the use of ERT can save money at the scale of a drilling programme if ERT improves the success rate by only 5% as compared to the success rate obtained with 1D techniques. Finally, this study demonstrates, using the example of Benin, that the use of electrical resistivity profiling and sounding for siting boreholes in weathered hard rocks of western Africa should be discarded and replaced by the use of ERT technique, more efficient.

  5. Association between inaccurate estimation of body size and obesity in schoolchildren.

    Science.gov (United States)

    Costa, Larissa da Cunha Feio; Silva, Diego Augusto Santos; Almeida, Sebastião de Sousa; de Vasconcelos, Francisco de Assis Guedes

    2015-01-01

    To investigate the prevalence of inaccurate estimation of own body size among Brazilian schoolchildren of both sexes aged 7-10 years, and to test whether overweight/obesity; excess body fat and central obesity are associated with inaccuracy. Accuracy of body size estimation was assessed using the Figure Rating Scale for Brazilian Children. Multinomial logistic regression was used to analyze associations. The overall prevalence of inaccurate body size estimation was 76%, with 34% of the children underestimating their body size and 42% overestimating their body size. Obesity measured by body mass index was associated with underestimation of body size in both sexes, while central obesity was only associated with overestimation of body size among girls. The results of this study suggest there is a high prevalence of inaccurate body size estimation and that inaccurate estimation is associated with obesity. Accurate estimation of own body size is important among obese schoolchildren because it may be the first step towards adopting healthy lifestyle behaviors.

  6. A Practical pedestrian approach to parsimonious regression with inaccurate inputs

    Directory of Open Access Journals (Sweden)

    Seppo Karrila

    2014-04-01

    Full Text Available A measurement result often dictates an interval containing the correct value. Interval data is also created by roundoff, truncation, and binning. We focus on such common interval uncertainty in data. Inaccuracy in model inputs is typically ignored on model fitting. We provide a practical approach for regression with inaccurate data: the mathematics is easy, and the linear programming formulations simple to use even in a spreadsheet. This self-contained elementary presentation introduces interval linear systems and requires only basic knowledge of algebra. Feature selection is automatic; but can be controlled to find only a few most relevant inputs; and joint feature selection is enabled for multiple modeled outputs. With more features than cases, a novel connection to compressed sensing emerges: robustness against interval errors-in-variables implies model parsimony, and the input inaccuracies determine the regularization term. A small numerical example highlights counterintuitive results and a dramatic difference to total least squares.

  7. Endoscopic Localization of Colon Cancer Is Frequently Inaccurate.

    Science.gov (United States)

    Nayor, Jennifer; Rotman, Stephen R; Chan, Walter W; Goldberg, Joel E; Saltzman, John R

    2017-08-01

    Colonoscopic location of a tumor can influence both the surgical procedure choice and overall treatment strategy. To determine the accuracy of colonoscopy in determining the location of colon cancer compared to surgical localization and to elucidate factors that predict discordant colon cancer localization. We conducted a retrospective cross-sectional study of colon cancers diagnosed on colonoscopy at two academic tertiary-care hospitals and two affiliated community hospitals from 2012 to 2014. Colon cancer location was obtained from the endoscopic and surgical pathology reports and characterized by colon segment. We collected data on patient demographics, tumor characteristics, endoscopic procedure characteristics, surgery planned, and surgery performed. Univariate analyses using Chi-squared test and multivariate analysis using forward stepwise logistic regression were performed to determine factors that predict discordant colon cancer localization. There were 110 colon cancer cases identified during the study period. Inaccurate endoscopic colon cancer localization was found in 29% (32/110) of cases. These included 14 cases (12.7%) that were discordant by more than one colonic segment and three cases where the presurgical planned procedure was significantly changed at the time of surgery. On univariate analyses, right-sided colon lesions were associated with increased inaccuracy (43.8 vs 24.4%, p = 0.04). On multivariate analysis, right-sided colon lesions remained independently associated with inaccuracy (OR 1.74, 95% CI 1.03-2.93, p = 0.04). Colon cancer location as determined by colonoscopy is often inaccurate, which can result in intraoperative changes to surgical management, particularly in the right colon.

  8. G. Dupuytren's contracture: an inaccurate denomination.

    Science.gov (United States)

    Vrebos, J

    2009-10-01

    The question of priority in describing 'Dupuytren's disease' as a result of permanent retraction of the palmar aponeurosis has been debated for a long time. This article tries to identify the pioneers who were involved in the research of the origin of permanent contracture of fingers and palm of the hand, and to find out to whom the priority of this affection should be attributed. Selected passages of several authors, as well as of Dupuytren's writings (mainly in italics and translated into English) are used to try and find the truth concerning the primary description of the disease.

  9. Memory conformity affects inaccurate memories more than accurate memories.

    Science.gov (United States)

    Wright, Daniel B; Villalba, Daniella K

    2012-01-01

    After controlling for initial confidence, inaccurate memories were shown to be more easily distorted than accurate memories. In two experiments groups of participants viewed 50 stimuli and were then presented with these stimuli plus 50 fillers. During this test phase participants reported their confidence that each stimulus was originally shown. This was followed by computer-generated responses from a bogus participant. After being exposed to this response participants again rated the confidence of their memory. The computer-generated responses systematically distorted participants' responses. Memory distortion depended on initial memory confidence, with uncertain memories being more malleable than confident memories. This effect was moderated by whether the participant's memory was initially accurate or inaccurate. Inaccurate memories were more malleable than accurate memories. The data were consistent with a model describing two types of memory (i.e., recollective and non-recollective memories), which differ in how susceptible these memories are to memory distortion.

  10. Clinical results of galantase for diarrhea due to gynecological radiotherapy

    International Nuclear Information System (INIS)

    Tokunaga, Akiteru; Higuchi, Akira.

    1977-01-01

    Galantase, a preparation of lactose-decomposing enzyme, was used for 20 radiotherapeutic patients for prevention and treatment of diarrhea. The results were compared with those of 58 control cases without administration. In the 58 cases, the timing of onset of diarrhea during irradiation was examined, and the mechanism of onset of radioinjury in the digestive tract was discussed. Galantase 6 g/day was administered to 13 of the 20 patients simultaneously with institution of irradiation and to 7 patients simultaneously with the onset of diarrhea during irradiation. As radiotherapy, the patients were given remote cobalt irradiation 5 times a week, each consisting of 200 rad, a total dose of 5,000 rad, in a field of 14 - 16 x 14 - 16 cm by way of 2 ports (anterior and posterior). Diarrhea and soft stool both appeared by irradiation of less than 300 rad, and diarrhea was observed in 84%. Temporal diarrhea occurred in 3 of the 13 patients given galantase simultaneously with irradiation. Diarrhea continued for 6 days in one of the 6 cases in which galantase was administered simultaneously with the onset of diarrhea or watery stool. In the other 5, the stool recovered to be soft or normal 2-3 days after administration. Diarrhea during irradiaion appeared in 21.4% of the cases given galantase and 42.1% of those without it. The clinical value of galantase was recognized. (Chiba, N.)

  11. Avoiding inaccurate interpretations when performing ultrasonic tests on welded joints

    International Nuclear Information System (INIS)

    Crostack, H.A.; Schuster, V.

    1992-01-01

    As reported in this article, conventional procedures for assessing errors when performing ultrasonic tests on weldes seams of ten no longer meet modern-day requirements. However, the safety of welded seams can be assessed considerably more accurately by adopting suitable assessment techniques, such as pattern recognition. This will mean that inaccurate interpretations can be ruled out to a large extent. (RHM) [de

  12. Leg mass characteristics of accurate and inaccurate kickers--an Australian football perspective.

    Science.gov (United States)

    Hart, Nicolas H; Nimphius, Sophia; Cochrane, Jodie L; Newton, Robert U

    2013-01-01

    Athletic profiling provides valuable information to sport scientists, assisting in the optimal design of strength and conditioning programmes. Understanding the influence these physical characteristics may have on the generation of kicking accuracy is advantageous. The aim of this study was to profile and compare the lower limb mass characteristics of accurate and inaccurate Australian footballers. Thirty-one players were recruited from the Western Australian Football League to perform ten drop punt kicks over 20 metres to a player target. Players were separated into accurate (n = 15) and inaccurate (n = 16) groups, with leg mass characteristics assessed using whole body dual energy x-ray absorptiometry (DXA) scans. Accurate kickers demonstrated significantly greater relative lean mass (P ≤ 0.004) and significantly lower relative fat mass (P ≤ 0.024) across all segments of the kicking and support limbs, while also exhibiting significantly higher intra-limb lean-to-fat mass ratios for all segments across both limbs (P ≤ 0.009). Inaccurate kickers also produced significantly larger asymmetries between limbs than accurate kickers (P ≤ 0.028), showing considerably lower lean mass in their support leg. These results illustrate a difference in leg mass characteristics between accurate and inaccurate kickers, highlighting the potential influence these may have on technical proficiency of the drop punt.

  13. Near-Nash equilibrium strategies for LQ differential games with inaccurate state information

    Directory of Open Access Journals (Sweden)

    2006-01-01

    Full Text Available ε -Nash equilibrium or “near equilibrium” for a linear quadratic cost game is considered. Due to inaccurate state information, the standard solution for feedback Nash equilibrium cannot be applied. Instead, an estimation of the players' states is substituted into the optimal control strategies equation obtained for perfect state information. The magnitude of the ε in the ε -Nash equilibrium will depend on the quality of the estimation process. To illustrate this approach, a Luenberger-type observer is used in the numerical example to generate the players' state estimates in a two-player non-zero-sum LQ differential game.

  14. Inaccurate preoperative imaging assessment on biliary anatomy not increases biliary complications after living donor liver transplantation

    International Nuclear Information System (INIS)

    Xu Xiao; Wei Xuyong; Ling Qi; Wang Kai; Bao Haiwei; Xie Haiyang; Zhou Lin; Zheng Shusen

    2012-01-01

    Backgrounds and aims: Accurate assessment of graft bile duct is important to plan surgical procedure. Magnetic resonance cholangiopancreatography (MRCP) has become an important diagnostic procedure in evaluation of pancreaticobiliary ductal abnormalities and has been reported as highly accurate. We aim to estimate the efficacy of preoperative MRCP on depicting biliary anatomy in living donor liver transplantation (LDLT), and to determine whether inaccurate preoperative imaging assessment would increase the biliary complications after LDLT. Methods: The data of 118 cases LDLT were recorded. Information from preoperative MRCP was assessed using intraoperative cholangiography (IOC) as the gold standard. The possible risk factors of recipient biliary complications were analyzed. Results: Of 118 donors, 84 had normal anatomy (type A) and 34 had anatomic variants (19 cases of type B, 9 cases of type C, 1 case of type E, 2 cases of type F and 3 cases of type I) confirmed by IOC. MRCP correctly predicted all 84 normal cases and 17 of 34 variant cases, and showed an accuracy of 85.6% (101/118). The incidence of biliary complications was comparable between cases with accurate and inaccurate classification of biliary tree from MRCP, and between cases with normal and variant anatomy of bile duct. While cases with graft duct opening ≤5 mm showed a significant higher incidence of total biliary complications (21.1% vs. 6.6%, P = 0.028) and biliary stricture (10.5% vs. 1.6%, P = 0.041) compared with cases with large duct opening >5 mm. Conclusion: MRCP could correctly predict normal but not variant biliary anatomy. Inaccurate assessment of biliary anatomy from MRCP not increases the rate of biliary complications, while small-sized graft duct may cause an increase in biliary complications particularly biliary stricture after LDLT.

  15. The Impact of Inaccurate Internet Health Information in a Secondary School Learning Environment

    Science.gov (United States)

    Edwards, Christine; Richards-Kortum, Rebecca

    2008-01-01

    Background Patients in the United States commonly use the Internet to acquire health information. While a significant amount of health-related information is available on the Internet, the accuracy of this information is highly variable. Objectives The objective of the study was to determine how effectively students can assess the accuracy of Internet-based material when gathering information on a controversial medical topic using simple keyword searches. Methods A group of 34 students from the science magnet high school in Houston, Texas searched for the terms “vaccine safety” and “vaccine danger” using Google and then answered questions regarding the accuracy of the health information on the returned sites. The students were also asked to describe the lessons they learned in the exercise and to answer questions regarding the strength of evidence for seven statements regarding vaccinations. Because of the surprising revelation that the majority of students left the exercise with inaccurate information concerning the safety and efficacy of vaccines, these same students participated in a follow-up study in which a fact-based vaccine video was shown, after which the assessment of student knowledge was repeated. Results Of the 34 participants, 20 (59%) thought that the Internet sites were accurate on the whole, even though over half of the links (22 out of 40, 55%) that the students viewed were, in fact, inaccurate on the whole. A high percentage of the students left the first exercise with significant misconceptions about vaccines; 18 of the 34 participants (53%) reported inaccurate statements about vaccines in the lessons they learned. Of the 41 verifiable facts about vaccines that were reported by participants in their lessons-learned statement, 24 of those facts (59%) were incorrect. Following presentation of the film, the majority of students left the exercise with correct information about vaccines, based on their lessons-learned statement. In this case

  16. SU-E-T-377: Inaccurate Positioning Might Introduce Significant MapCheck Calibration Error in Flatten Filter Free Beams

    International Nuclear Information System (INIS)

    Wang, S; Chao, C; Chang, J

    2014-01-01

    Purpose: This study investigates the calibration error of detector sensitivity for MapCheck due to inaccurate positioning of the device, which is not taken into account by the current commercial iterative calibration algorithm. We hypothesize the calibration is more vulnerable to the positioning error for the flatten filter free (FFF) beams than the conventional flatten filter flattened beams. Methods: MapCheck2 was calibrated with 10MV conventional and FFF beams, with careful alignment and with 1cm positioning error during calibration, respectively. Open fields of 37cmx37cm were delivered to gauge the impact of resultant calibration errors. The local calibration error was modeled as a detector independent multiplication factor, with which propagation error was estimated with positioning error from 1mm to 1cm. The calibrated sensitivities, without positioning error, were compared between the conventional and FFF beams to evaluate the dependence on the beam type. Results: The 1cm positioning error leads to 0.39% and 5.24% local calibration error in the conventional and FFF beams respectively. After propagating to the edges of MapCheck, the calibration errors become 6.5% and 57.7%, respectively. The propagation error increases almost linearly with respect to the positioning error. The difference of sensitivities between the conventional and FFF beams was small (0.11 ± 0.49%). Conclusion: The results demonstrate that the positioning error is not handled by the current commercial calibration algorithm of MapCheck. Particularly, the calibration errors for the FFF beams are ~9 times greater than those for the conventional beams with identical positioning error, and a small 1mm positioning error might lead to up to 8% calibration error. Since the sensitivities are only slightly dependent of the beam type and the conventional beam is less affected by the positioning error, it is advisable to cross-check the sensitivities between the conventional and FFF beams to detect

  17. Entanglement-fidelity relations for inaccurate ancilla-driven quantum computation

    International Nuclear Information System (INIS)

    Morimae, Tomoyuki; Kahn, Jonas

    2010-01-01

    It was shown by T. Morimae [Phys. Rev. A 81, 060307(R) (2010)] that the gate fidelity of an inaccurate one-way quantum computation is upper bounded by a decreasing function of the amount of entanglement in the register. This means that a strong entanglement causes the low gate fidelity in the one-way quantum computation with inaccurate measurements. In this paper, we derive similar entanglement-fidelity relations for the inaccurate ancilla-driven quantum computation. These relations again imply that a strong entanglement in the register causes the low gate fidelity in the ancilla-driven quantum computation if the measurements on the ancilla are inaccurate.

  18. The Test of Inaccurate Position of Renography Detector to Relative UptakeFigure and Individual Excretion

    International Nuclear Information System (INIS)

    Bambang-Supardiyono; Prayitno

    2000-01-01

    Accuracy of detector position toward the kidney location (preciseposition) in renography will resulting the maximum count figure, detectorposition change from the precise point (inaccurate) will decreasing the countrate. Therefore for it had been simulated the influence of count figure ofright kidney (fixed left kidney count) ± 5 % to ± 20 % to relativeuptake figure and individual excretion. Based on the calculation it was foundthat the relation of detector position ± 0.5 cm to ± 2 cm from theprecise point will have effect to relative uptake figure ± (1.25 % to 5.00%), the fixed individual excretion figure. The change is still can beaccepted because the qualitative information with 10 % accuracy is stillacceptable. (author)

  19. Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota.

    Directory of Open Access Journals (Sweden)

    Alena V Makarova

    2011-01-01

    Full Text Available Mammalian Pol ι has an unusual combination of properties: it is stimulated by Mn(2+ ions, can bypass some DNA lesions and misincorporates "G" opposite template "T" more frequently than incorporates the correct "A." We recently proposed a method of detection of Pol ι activity in animal cell extracts, based on primer extension opposite the template T with a high concentration of only two nucleotides, dGTP and dATP (incorporation of "G" versus "A" method of Gening, abbreviated as "misGvA". We provide unambiguous proof of the "misGvA" approach concept and extend the applicability of the method for the studies of variants of Pol ι in the yeast model system with different cation cofactors. We produced human Pol ι in baker's yeast, which do not have a POLI ortholog. The "misGvA" activity is absent in cell extracts containing an empty vector, or producing catalytically dead Pol ι, or Pol ι lacking exon 2, but is robust in the strain producing wild-type Pol ι or its catalytic core, or protein with the active center L62I mutant. The signature pattern of primer extension products resulting from inaccurate DNA synthesis by extracts of cells producing either Pol ι or human Pol η is different. The DNA sequence of the template is critical for the detection of the infidelity of DNA synthesis attributed to DNA Pol ι. The primer/template and composition of the exogenous DNA precursor pool can be adapted to monitor replication fidelity in cell extracts expressing various error-prone Pols or mutator variants of accurate Pols. Finally, we demonstrate that the mutation rates in yeast strains producing human DNA Pols ι and η are not elevated over the control strain, despite highly inaccurate DNA synthesis by their extracts.

  20. Results of endoscopic surgery and intralesional steroid therapy for airway compromise due to tracheobronchial Wegener's granulomatosis

    Directory of Open Access Journals (Sweden)

    S. A. R. Nouraei

    2008-04-01

    Full Text Available Background: Upper airway compromise due to tracheobronchial stenosis commonly occurs in patients with Wegener's Granulomatosis (WG. There is at present no consensus on the optimal management of this life-threatening condition. Objective: To assess the results of laryngo-tracheo-bronchoscopy, intralesional steroid therapy, laser surgery, and dilatation in managing obstructive tracheobronchial WG. Methods: Records of eighteen previously-untreated stridulous patients with obstructive tracheobronchial WG, treated between 2004 and 2006 were prospectively recorded on an airway database and retrospectively reviewed. Information about patient and lesion characteristics and treatment details were recorded. Treatment progress was illustrated using a timeline plot, and intervention-free intervals were calculated with actuarial analysis. Results: There were nine males and the average age at presentation was 40 (16 years [range 13–74]. There were thirteen patients with tracheal, and five patients with tracheal and bronchial lesions. The average tracheal lesion height was 8 (3 mm, located 23 (9 mm below the glottis. There were 1, 10 and 7 Myer-Cotton grade I, II and III lesions respectively. Mean intervention-free interval following minimally-invasive treatment was 26 (2.8 months. Following endobronchial therapy the median intervention-free interval was 22 months (p>0.8 vs. tracheal lesions. No patient required a tracheostomy or endoluminal stenting. Conclusions: Intralesional steroid therapy and conservative endoluminal surgery is an effective strategy for treating airway compromise due to active tracheal and bronchial WG, obviating the need for airway bypass or stenting. We recommend the combination of endotracheal dilatation, conservative laser surgery and steroid therapy as the standard of care for treating airway compromise due to obstructive tracheobronchial WG.

  1. False-positive results after environmental pinworm PCR testing due to Rhabditid nematodes in Corncob bedding.

    Science.gov (United States)

    Leblanc, Mathias; Berry, Kristina; Graciano, Sandy; Becker, Brandon; Reuter, Jon D

    2014-11-01

    Modern rodent colonies are housed in individually ventilated cages to protect the animals from contamination with adventitious pathogens. Standard health monitoring through soiled-bedding sentinels does not always detect infections, especially in the context of low pathogen prevalence. Recently proposed alternatives include analyzing environmental samples from the cages or rack exhaust by PCR to improve the detection of rodent pathogens but optimal sampling strategies have not yet been established for different microorganisms. Although generally very sensitive and specific, these molecular assays are not foolproof and subject to false-positive and -negative results and should always be interpreted cautiously with an overall understanding of the intrinsic controls and all the variables that may affect the results. Here, we report a limited Aspiculuris tetraptera outbreak in a mouse barrier facility that was detected by fecal PCR in sentinels and confirmed by fecal flotation and direct cecal examination of both sentinels and colony animals. The outbreak led to a widespread survey of all facilities for pinworms by using environmental PCR from ventilated rack exhaust plenums. Environmental PCR suggested an unexpected widespread contamination of all ventilated racks holding nonautoclaved cages, but results could not be confirmed in sentinel or colony animals by fecal flotation, cecal and colonic examination, or cage PCR testing. After additional investigation, the unexpected environmental PCR results were confirmed as false-positive findings due to the nonspecificity of the assay, leading to the amplification of rhabditid nematodes, which are not infectious in rodents but which contaminated the corncob bedding.

  2. Implications of inaccurate clinical nodal staging in pancreatic adenocarcinoma.

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    Swords, Douglas S; Firpo, Matthew A; Johnson, Kirsten M; Boucher, Kenneth M; Scaife, Courtney L; Mulvihill, Sean J

    2017-07-01

    Many patients with stage I-II pancreatic adenocarcinoma do not undergo resection. We hypothesized that (1) clinical staging underestimates nodal involvement, causing stage IIB to have a greater percent of resected patients and (2) this stage-shift causes discrepancies in observed survival. The Surveillance, Epidemiology, and End Results (SEER) research database was used to evaluate cause-specific survival in patients with pancreatic adenocarcinoma from 2004-2012. Survival was compared using the log-rank test. Single-center data on 105 patients who underwent resection of pancreatic adenocarcinoma without neoadjuvant treatment were used to compare clinical and pathologic nodal staging. In SEER data, medium-term survival in stage IIB was superior to IB and IIA, with median cause-specific survival of 14, 9, and 11 months, respectively (P < .001). Seventy-two percent of stage IIB patients underwent resection vs 28% in IB and 36% in IIA (P < .001). In our institutional data, 12.4% of patients had clinical evidence of nodal involvement vs 69.5% by pathologic staging (P < .001). Among clinical stage IA-IIA patients, 71.6% had nodal involvement by pathologic staging. Both SEER and institutional data support substantial underestimation of nodal involvement by clinical staging. This finding has implications in decisions regarding neoadjuvant therapy and analysis of outcomes in the absence of pathologic staging. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Patient Self-Assessment of Surgical Site Infection is Inaccurate.

    Science.gov (United States)

    Richter, Vered; Cohen, Matan J; Benenson, Shmuel; Almogy, Gideon; Brezis, Mayer

    2017-08-01

    Availability of surgical site infection (SSI) surveillance rates challenges clinicians, healthcare administrators and leaders and the public. The purpose of this report is to demonstrate the consequences patient self-assessment strategies have on SSI reporting rates. We performed SSI surveillance among patients undergoing general surgery procedures, including telephone follow-up 30 days after surgery. Additionally we undertook a separate validation study in which we compared patient self-assessments of SSI with surgeon assessment. Finally, we performed a meta-analysis of similar validation studies of patient self-assessment strategies. There were 22/266 in-hospital SSIs diagnosed (8.3%), and additional 16 cases were detected through the 30-day follow-up. In total, the SSI rate was 16.8% (95% CI 10.1-18.5). In the validation survey, we found patient telephone surveillance to have a sensitivity of 66% (95% CI 40-93%) and a specificity of 90% (95% CI 86-94%). The meta-analysis included five additional studies. The overall sensitivity was 83.3% (95% CI 79-88%), and the overall specificity was 97.4% (95% CI 97-98%). Simulation of the meta-analysis results divulged that when the true infection rate is 1%, reported rates would be 4%; a true rate of 50%, the reported rates would be 43%. Patient self-assessment strategies in order to fulfill 30-day SSI surveillance misestimate SSI rates and lead to an erroneous overall appreciation of inter-institutional variation. Self-assessment strategies overestimate SSIs rate of institutions with high-quality performance and underestimate rates of poor performance. We propose such strategies be abandoned. Alternative strategies of patient follow-up strategies should be evaluated in order to provide valid and reliable information regarding institutional performance in preventing patient harm.

  4. Oncological, surgical and functional results of the treatment of patients after hemipelvectomy due to metastases

    Directory of Open Access Journals (Sweden)

    Grzegorz Guzik

    2018-02-01

    Full Text Available Abstract Background Metastatic lesions localized in the pelvis cause pain, pathological fractures and decrease quality of patients life. Limited data are avaliable to compare the oncological, surgical and functional outcomes after different surgeries in patients with metastatic pelvic tumors. Most of the works presents the results of hemipelvectomy performed in patients with primary malignant bone tumors. The objectives of this study were to assess the outcome of patients after internal hemipelvectomy due to cancer metastases. Methods Over the period 2010–2015 at the Department of Orthopaedic Oncology in Brzozów, 34 patients with metastases to the pelvis were treated. This study group comprised of 21 men and 13 women. The mean age was 67 (range: 51–79 for men and 56 (range: 41–77 for women. The majority of the treated patients suffered from myeloma (12 patients and breast cancer (8 patients. Following the Enneking system classification guidelines, tumours were found in zone I (5 cases, zone II (18 cases, zone III (4 cases. Tumour involvement of both zones (II and III considered 7 patients. The following resections were accomplished: wide in 11 cases, marginal in 17 cases, and intralesional in 6 cases. 18 patients were postoperatively treated with 8 Gy single-dose radiotherapy. 25 patients underwent bone reconstruction using either Lumic prostheses (9 cases or the Harrington technique (16 cases. The mean follow-up period was 2.1 years (range: 1.2–6 years. The analysis covered patients’ survival, number of local recurrences, functional results and effectiveness of surgical treatment, considering the type, number and reason of complications. Results Eight patients died. Overal survival calculated with Kaplan- Meier curve was 48.2% for 34 patients. Mean survival was 3.85 years. There were no statistically significant differences in overall survival depending on the type of metastasis resection. In this group, local tumour recurrences

  5. Field Observation of Soil Displacements Resulting Due Unsupported Excavation and Its Effects on Proposed Adjacent Piles

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    Ala Nasir Al-Jorany

    2016-06-01

    Full Text Available Soil movement resulting due unsupported excavation nearby axially loaded piles imposes significant structural troubles on geotechnical engineers especially for piles that are not designed to account for loss of lateral confinement. In this study the field excavation works of 7.0 m deep open tunnel was continuously followed up by the authors. The work is related to the project of developing the Army canal in the east of Baghdad city in Iraq. A number of selected points around the field excavation are installed on the ground surface at different horizontal distance. The elevation and coordinates of points are recorded during 23 days with excavation progress period. The field excavation process was numerically simulated by using the finite element package PLAXIS 3D foundation. The obtained analysis results regarding the displacements of the selected points are compared with the field observation for verification purpose. Moreover, finite element analysis of axially loaded piles that are presumed to be existed at the locations of the observation points is carried out to study the effect of excavation on full scale piles behaviors. The field observation monitored an upward movement and positive lateral ground movement for shallow excavation depth. Later on and as the excavation process went deeper, a downward movement and negative lateral ground movement are noticed. The analyses results are in general well agreed with the monitored values of soil displacements at the selected points. It is found also that there are obvious effects of the nearby excavation on the presumed piles in terms of displacements and bending moments.

  6. Distinguishing highly confident accurate and inaccurate memory: insights about relevant and irrelevant influences on memory confidence

    Science.gov (United States)

    Chua, Elizabeth F.; Hannula, Deborah E.; Ranganath, Charan

    2012-01-01

    It is generally believed that accuracy and confidence in one’s memory are related, but there are many instances when they diverge. Accordingly, it is important to disentangle the factors which contribute to memory accuracy and confidence, especially those factors that contribute to confidence, but not accuracy. We used eye movements to separately measure fluent cue processing, the target recognition experience, and relative evidence assessment on recognition confidence and accuracy. Eye movements were monitored during a face-scene associative recognition task, in which participants first saw a scene cue, followed by a forced-choice recognition test for the associated face, with confidence ratings. Eye movement indices of the target recognition experience were largely indicative of accuracy, and showed a relationship to confidence for accurate decisions. In contrast, eye movements during the scene cue raised the possibility that more fluent cue processing was related to higher confidence for both accurate and inaccurate recognition decisions. In a second experiment, we manipulated cue familiarity, and therefore cue fluency. Participants showed higher confidence for cue-target associations for when the cue was more familiar, especially for incorrect responses. These results suggest that over-reliance on cue familiarity and under-reliance on the target recognition experience may lead to erroneous confidence. PMID:22171810

  7. Intravitreal bevacizumab for macular edema due to branch retinal vein occlusion: 12-month results

    OpenAIRE

    Demir M; Oba E; Gulkilik G; Odabasi M; Ozdal E

    2011-01-01

    Mehmet Demir, Ersin Oba, Gökhan Gulkilik, Mahmut Odabasi, Erhan OzdalSisli Etfal Training and Research Hospital, Eye Clinic, Sisli, Istanbul, TurkeyPurpose: To present the functional and anatomic changes after intravitreal bevacizumab in eyes with macular edema (ME) due to branch retinal vein occlusion (BRVO).Design: The study was a retrospective study.Materials and methods: The study included 31 patients with ME due to BRVO. We compared the examination findings of patients with ME b...

  8. Legal termination of a pregnancy resulting from transplanted cryopreserved ovarian tissue due to cancer recurrence

    DEFF Research Database (Denmark)

    Ernst, Emil Hagen; Offersen, Birgitte Vrou; Andersen, Claus Yding

    2013-01-01

    To report on a woman who conceived naturally and had a normal intrauterine pregnancy following transplantation of frozen/thawed ovarian tissue but decided to have an early abortion due to recurrence of breast cancer.......To report on a woman who conceived naturally and had a normal intrauterine pregnancy following transplantation of frozen/thawed ovarian tissue but decided to have an early abortion due to recurrence of breast cancer....

  9. The evolution of future geogenic matter fluxes due Enhanced Weathering: Results from the Antwerp Experiment

    Science.gov (United States)

    Hartmann, Jens; Weiss, Andreas; Struyf, Eric; Schoelynck, Jonas; Meire, Patrick; Amann, Thorben

    2015-04-01

    Understanding the evolution of geogenic matter fluxes in soils due the application of rock products ontop of soils is relevant to evaluate alteration of soil solutions and saturation states of solutes. In the future the practice of applying rock products will continue and areas affected will likely spread (Hartmann et al., 2013). This trend will likely be fuelled by attempts to optimize carbon dioxide removal by increasing biomass production, soil organic carbon stocks, increase crop production or afforestation. All those efforts demand a certain amount of geogenic nutrients, which need to be replaced. To investigate the release patterns and the downward transport of an array of elements, and to study their fate as well as reaction processes, altered through this practice, a mesocosm experiment was established at Antwerp University. Extended results will be presented (c.f., Weiss et al., 2014) focusing on the release and transport of DIC (dissolved inorganic carbon) and Mg (magnesium) in the soil column downwards after the application of 22 kg m-2 olivine powder. Elevated DIC and Mg concentrations are detected in case of olivine is applied to mesocosms with wheat and barley, if compared to the mesocsoms without plants, and without olivine. The change patterns in concentrations and fluxes will be discussed. Hartmann, J., et al. (2013) Enhanced chemical weathering as a geoengineering strategy to reduce atmospheric carbon dioxide, supply nutrients, and mitigate ocean acidification. Reviews of Geophysics; 51(2), 113-149. doi: 10.1002/rog.20004 Weiss, A., et al. (2014) The overlooked compartment of the critical-zone-complex, considering the evolution of future geogenic matter fluxes: Agricultural topsoils. Procedia Earth and Planetary Science, 10, 339-342. doi:10.1016/j.proeps.2014.08.032

  10. Accurate and inaccurate HIV transmission beliefs, stigmatizing and HIV protection motivation in northern Thailand

    NARCIS (Netherlands)

    Boer, H.; Emons, P.A.A.

    2004-01-01

    We assessed the relation between accurate beliefs about HIV transmission and inaccurate beliefs about HIV transmission and emotional reactions to people with AIDS (PWA) and AIDS risk groups, stigmatizing attitudes and motivation to protect from HIV. In Chiang Rai, northern Thailand, 219 respondents

  11. A non-convex variational approach to photometric stereo under inaccurate lighting

    DEFF Research Database (Denmark)

    Quéau, Yvain; Wu, Tao; Lauze, Francois Bernard

    2017-01-01

    This paper tackles the photometric stereo problem in the presence of inaccurate lighting, obtained either by calibration or by an uncalibrated photometric stereo method. Based on a precise modeling of noise and outliers, a robust variational approach is introduced. It explicitly accounts for self...

  12. Study of bantam miRNA expression in brain tumour resulted due to ...

    Indian Academy of Sciences (India)

    ANIMESH BANERJEE

    2017-06-19

    Jun 19, 2017 ... The cells expressing bantam miRNA are GFP negative, as bantam interacts with RNA induced silencing com- plex (RISC) to inhibit GFP translation by binding to the. 3 UTR region of this sensor transcript. The cell that does not have bantam miRNA expression has GFP due to the absence of a translational ...

  13. Inaccurate Citations in Biomedical Journalism: Effect on the Impact Factor of the American Journal of Roentgenology.

    Science.gov (United States)

    Karabulut, Nevzat

    2017-03-01

    The aim of this study is to investigate the frequency of incorrect citations and its effects on the impact factor of a specific biomedical journal: the American Journal of Roentgenology. The Cited Reference Search function of Thomson Reuters' Web of Science database (formerly the Institute for Scientific Information's Web of Knowledge database) was used to identify erroneous citations. This was done by entering the journal name into the Cited Work field and entering "2011-2012" into the Cited Year(s) field. The errors in any part of the inaccurately cited references (e.g., author names, title, year, volume, issue, and page numbers) were recorded, and the types of errors (i.e., absent, deficient, or mistyped) were analyzed. Erroneous citations were corrected using the Suggest a Correction function of the Web of Science database. The effect of inaccurate citations on the impact factor of the AJR was calculated. Overall, 183 of 1055 citable articles published in 2011-2012 were inaccurately cited 423 times (mean [± SD], 2.31 ± 4.67 times; range, 1-44 times). Of these 183 articles, 110 (60.1%) were web-only articles and 44 (24.0%) were print articles. The most commonly identified errors were page number errors (44.8%) and misspelling of an author's name (20.2%). Incorrect citations adversely affected the impact factor of the AJR by 0.065 in 2012 and by 0.123 in 2013. Inaccurate citations are not infrequent in biomedical journals, yet they can be detected and corrected using the Web of Science database. Although the accuracy of references is primarily the responsibility of authors, the journal editorial office should also define a periodic inaccurate citation check task and correct erroneous citations to reclaim unnecessarily lost credit.

  14. Autosomal recessive dilated cardiomyopathy due to DOLK mutations results from abnormal dystroglycan O-mannosylation.

    Directory of Open Access Journals (Sweden)

    Dirk J Lefeber

    2011-12-01

    Full Text Available Genetic causes for autosomal recessive forms of dilated cardiomyopathy (DCM are only rarely identified, although they are thought to contribute considerably to sudden cardiac death and heart failure, especially in young children. Here, we describe 11 young patients (5-13 years with a predominant presentation of dilated cardiomyopathy (DCM. Metabolic investigations showed deficient protein N-glycosylation, leading to a diagnosis of Congenital Disorders of Glycosylation (CDG. Homozygosity mapping in the consanguineous families showed a locus with two known genes in the N-glycosylation pathway. In all individuals, pathogenic mutations were identified in DOLK, encoding the dolichol kinase responsible for formation of dolichol-phosphate. Enzyme analysis in patients' fibroblasts confirmed a dolichol kinase deficiency in all families. In comparison with the generally multisystem presentation in CDG, the nonsyndromic DCM in several individuals was remarkable. Investigation of other dolichol-phosphate dependent glycosylation pathways in biopsied heart tissue indicated reduced O-mannosylation of alpha-dystroglycan with concomitant functional loss of its laminin-binding capacity, which has been linked to DCM. We thus identified a combined deficiency of protein N-glycosylation and alpha-dystroglycan O-mannosylation in patients with nonsyndromic DCM due to autosomal recessive DOLK mutations.

  15. Beam loss due to the aperture limitation resulting from intrabeam scattering

    International Nuclear Information System (INIS)

    Lee, S.Y.

    1984-01-01

    Diffusion equation is used to evaluate the beam loss in the presence of aperture limitation resulting from the intrabeam scattering. We discuss the effect of different boundary conditions. Satisfactory beam intensity can be maintained within the proposed RHIC operation time

  16. Results from the Geodetic Observatory TIGO due to the Mw 8.8 Earthquake

    Science.gov (United States)

    Hase, H.; Böer, A.; Sierk, B.; Ihde, J.; Weber, G.; Wilmes, H.; Falk, R.; Hessels, U.; Neumaier, P.; Söhne, W.; Wziontek, H.; Engelhard, G.; Sobarzo, S.; Cifuentes, O.; Guaitiao, C.; Cona, I.; Avendaño, M.; Herrera, C.; Mora, V.; Fernandez, A.; Oñate, E.; Zaror, P.; Pedreros, F.; Zapata, O.

    2010-12-01

    The Geodetic Observatory TIGO is unique in Latin America. With its sensors and instruments it defines a reference point in the time, space and gravity field domain. Its operation started in 2002, for which reason data series documented the preseismic situation very well. With the Mw 8.8 earthquake on February 27, 2010, the entire observatory was exposed to strong motions due to its closeness to the epicenter. Since then the postseismic behaviour of the subduction zone can be studied and compared with the preseismic situation. TIGO provided continuous GPS/GLONASS data with 1s samples which give an insight to the mechanism of the decoupling of the Nazca and the South-American plate. The displacement of more than 3m had a duration of 30s at the beginning of the 147s duration of the earthquake. The displacement could be confirmed afterwards with VLBI and SLR methods. TIGO used its absolute gravity meter in an unusual way with weekly measurements on the same monument. These data show an irregularity during the last 3 weeks before the earthquake. Finally the postseismic movement to the west triggered by the earthquake and registered by geodetic space techniques indicate that the western expansion of the South-American plate did not stop yet. The pre- and post-seismic displacement vectors differ by less than 180° which might be explained by a fractional strike slip in the mega thrust. The coincidence of the epicenter with one of the keystations for global reference frames showed deficiencies by the linear modelling of tectonical movements in terrestial reference frames. This problem calls for near-real time reference frames.

  17. [Utilization of the health care system due to somatoform complaints -- results of a representative survey].

    Science.gov (United States)

    Hessel, Aike; Geyer, Michael; Hinz, Andreas; Brahler, Elmar

    2005-01-01

    Utilization of the health care system is not determined by the presence of an organic illness, but by a multitude of interacting factors. This applies particularly to somatoform complaints and disorders, in the context of which the health care system is used very intensively and inadequately in relation to the disorder. The present paper summarizes the frequency of somatoform complaints in the general population and health care utilization due to these complaints. On the basis of a survey carried out in 2002 for a representative population of 2089 persons (aged 14 to 92 years), the prevalence of somatoform complaints during a period of 2 years was determined. In this survey, physical complaints were defined as being somatoform when they seriously affected the person's well-being but exhibited a disparity between objective diagnostic findings and subjective experience. The psychosocial aspects were also determined. When somatoform complaints were identified, the specific utilization of the healthcare system for them was investigated. Somatoform complaints are very frequent in Germany: 8.3% of the population claim to suffer from clinically relevant somatoform disorders that fully meet the criteria mentioned above. The health care system is used heavily for these complaints. Within the last two years, each test person suffering from somatoform disorders consulted a physician a mean 18 times and was incapable of working for a mean of 20 days. 16% of these persons were hospitalized, 9 % received treatment at a health resort, 9 % retired, etc. The considerable utilization of health care services is an essential element of somatoform pathology and has immense medico-political relevance. The most important prerequisite for handling the 'commitment to health care system' symptom is thorough training of all physicians in the basics of somato-psycho-social medicine. This will be an important measure for cost reduction in the health care system.

  18. Recent results for electron scattering from biomolecules and molecules formed due to plasma treatment of biomass

    Science.gov (United States)

    Brunger, Michael

    2016-09-01

    We have been concentrating our recent experimental studies, for determining absolute cross sections, on both biomolecules (e.g. pyrimidine and benzoquinone) and molecules that result when biomass undergoes treatment by plasmas (e.g. phenol and furfural). All this work was supported and informed by computations from the Brazilian SMC groups and the Madrid IAM-SCAR group. A major rationale for these investigations was to provide cross section data for relevant modelling studies, and in this talk I will also present some results from those modelling studies. Possible further investigations will be canvassed in this presentation. Work done in conjunction with: D. B. Jones, L. Campbell, R. D. White, S. J. Buckman, M. A. P. Lima, M. C. A. Lopes, M. H. F. Bettega, M. T. do N. Varella, R. F. da Costa, G. García, P. Limão-Vieira, D. H. Madison, O. Ingólfsson and many other friends and colleagues.

  19. Modelling lung cancer due to radon and smoking in WISMUT miners: Preliminary results

    International Nuclear Information System (INIS)

    Bijwaard, H.; Dekkers, F.; Van Dillen, T.

    2011-01-01

    A mechanistic two-stage carcinogenesis model has been applied to model lung-cancer mortality in the largest uranium-miner cohort available. Models with and without smoking action both fit the data well. As smoking information is largely missing from the cohort data, a method has been devised to project this information from a case-control study onto the cohort. Model calculations using 256 projections show that the method works well. Preliminary results show that if an explicit smoking action is absent in the model, this is compensated by the values of the baseline parameters. This indicates that in earlier studies performed without smoking information, the results obtained for the radiation parameters are still valid. More importantly, the inclusion of smoking-related parameters shows that these mainly influence the later stages of lung-cancer development. (authors)

  20. Bias in logistic regression due to imperfect diagnostic test results and practical correction approaches.

    Science.gov (United States)

    Valle, Denis; Lima, Joanna M Tucker; Millar, Justin; Amratia, Punam; Haque, Ubydul

    2015-11-04

    Logistic regression is a statistical model widely used in cross-sectional and cohort studies to identify and quantify the effects of potential disease risk factors. However, the impact of imperfect tests on adjusted odds ratios (and thus on the identification of risk factors) is under-appreciated. The purpose of this article is to draw attention to the problem associated with modelling imperfect diagnostic tests, and propose simple Bayesian models to adequately address this issue. A systematic literature review was conducted to determine the proportion of malaria studies that appropriately accounted for false-negatives/false-positives in a logistic regression setting. Inference from the standard logistic regression was also compared with that from three proposed Bayesian models using simulations and malaria data from the western Brazilian Amazon. A systematic literature review suggests that malaria epidemiologists are largely unaware of the problem of using logistic regression to model imperfect diagnostic test results. Simulation results reveal that statistical inference can be substantially improved when using the proposed Bayesian models versus the standard logistic regression. Finally, analysis of original malaria data with one of the proposed Bayesian models reveals that microscopy sensitivity is strongly influenced by how long people have lived in the study region, and an important risk factor (i.e., participation in forest extractivism) is identified that would have been missed by standard logistic regression. Given the numerous diagnostic methods employed by malaria researchers and the ubiquitous use of logistic regression to model the results of these diagnostic tests, this paper provides critical guidelines to improve data analysis practice in the presence of misclassification error. Easy-to-use code that can be readily adapted to WinBUGS is provided, enabling straightforward implementation of the proposed Bayesian models.

  1. Development of System for Evaluating Concrete Strength Deterioration Due to Radiation and Resultant Heat

    International Nuclear Information System (INIS)

    Maruyama, I.; Kontani, O.; Ishizawa, A.; Takizawa, M.; Sato, O.

    2012-01-01

    Evaluation of the soundness of concrete exposed to irradiation has been studied within the framework of a project of the Nuclear and Industrial Safety Agency (NISA) 'Japan Ageing Management Program for System Safety'. This contribution presents the background to the existing evaluation processes, a review of the irradiation exposure effect on concrete and needs for irradiation testing. Based on results of this study, working assumptions for the development of an evaluation system are derived, and an overall picture of a numerical model as well as a framework for evaluating concrete soundness under irradiated conditions are proposed. (author)

  2. [Preliminary analysis of serum enzymes indicators in childhood amputees due to earthquake resulting trauma].

    Science.gov (United States)

    Jiang, Xin; Liu, Lijun; Li, Hui

    2014-04-01

    To retrospectively analyze the serum enzymes in childhood amputees as a result of earthquake, and to discuss their clinical significance. From 150 children amputees who were victims of Sichuan Wenchuan earthquake in 2008 and Sichuan Lushan earthquake in 2013, 45 cases with complete records of serum enzymes examinations were reviewed retrospectively. They were divided into three groups: amputation group (n=6), fasciotomy decompression group (n=5), general trauma without injury to extremity group (n=34). Serum enzyme examination data were compared for statistical analysis to find the difference among groups. Ten children who were not victims of earthquake were selected from department of orthopaedics to serve as controls, and 20 adult amputees as a result of earthquake served as another control group. There were significant differences in injury severity scale (ISS) and the contents of all serum enzymes, including aspartate transaminase (AST), alanine aminotransferase (ALT), creatine kinase (CK), lactate dehydrogenase (LDH), and hydroxybutyrate dehydrogenase (HBDH), between the amputation group and other patients (FISS=15.474, PFCK=12.848, P<0.001; FLDH=13.126, P<0.001; FHBDH=13.186, P<0.001), and the difference in amputation group was even more significant. AST, LDH, HBDH in childhood amputees group were significantly higher than those in adult amputation group. The contents of ALT and CK were slightly increased. Serum enzyme contents were found to be significantly helpful for prediction of disease condition and prognosis. It was also found that CK was extremely helpful in assessing the degree of illness in patients with severe trauma, especially in patients complicated by severe soft tissue injury. In all the groups, of patients, it was found that CK rose from (129±62) U/L in non-earthquake induced trauma group to (44 208±39,788) U/L in earthquake amputation group, and it was thus increased more than 300 times. Its highest value even reached 117,513 U/L, which

  3. Fatal Small Intestinal Ischemia Due to Methamphetamine Intoxication: Report of a Case With Autopsy Results.

    Science.gov (United States)

    Attaran, Hamid

    2017-05-01

    Methamphetamine is one of the most common abused drugs, so its various effects on different body organs should be familiar to all physicians. Regarding its gastrointestinal sequels, there are few reports of ischemic colitis induced by its vasoconstrictive effects. This is the first report of isolated small intestinal infarction resulting in death following methamphetamine toxicity. A 40-year-old woman with a past history of medical treatment for obesity referred to hospital with severe chest and back pain, perspiration, nausea, agitation, high blood pressure, bradycardia and subsequent lethargy and vasomotor instability. Cardiac evaluations were normal, and a toxicologic urinalysis revealed methamphetamine. Later, abdominal pain predominated, and ultrasonography revealed signs of bowel infarction. She did not consent to surgery and succumbed afterward. At autopsy gangrene and perforation of distal ileum were found. The cause of death was determined as intestinal gangrene following methamphetamine toxicity. Methamphetamine has anorectic effects and so is used in some "diet pills"; Consumers may not even know they are using methamphetamine. Hence in cases of either known MA abuse or those using unknown weight reduction drugs presenting with gastrointestinal complaints or abdominal pain, intestinal ischemia should be kept in mind and if plausible, intervened promptly.

  4. Lower electricity prices and greenhouse gas emissions due to rooftop solar: empirical results for Massachusetts

    International Nuclear Information System (INIS)

    Kaufmann, Robert K.; Vaid, Devina

    2016-01-01

    Monthly and hourly correlations among photovoltaic (PV) capacity utilization, electricity prices, electricity consumption, and the thermal efficiency of power plants in Massachusetts reduce electricity prices and carbon emissions beyond average calculations. PV utilization rates are highest when the thermal efficiencies of natural gas fired power plants are lowest, which reduces emissions of CO 2 and CH 4 by 0.3% relative to the annual average emission rate. There is a positive correlation between PV utilization rates and electricity prices, which raises the implied price of PV electricity by up to 10% relative to the annual average price, such that the average MWh reduces electricity prices by $0.26–$1.86 per MWh. These price reductions save Massachusetts rate-payers $184 million between 2010 and 2012. The current and net present values of these savings are greater than the cost of solar renewable energy credits which is the policy instrument that is used to accelerate the installation of PV capacity. Together, these results suggest that rooftop PV is an economically viable source of power in Massachusetts even though it has not reached socket parity. - Highlights: •Implied price of PV up to 10% greater than the annual average price. •PV saves Massachusetts rate-payers $184 million in 2010–2012. •Annual savings are greater than the cost of solar renewable energy credits. •Savings rise longer lifetime of PV systems and pay period for SREC's shortened. •PV reduces emissions of CO 2 and CH 4 by 0.3% relative to the annual average.

  5. Protein loop modeling using a new hybrid energy function and its application to modeling in inaccurate structural environments.

    Directory of Open Access Journals (Sweden)

    Hahnbeom Park

    Full Text Available Protein loop modeling is a tool for predicting protein local structures of particular interest, providing opportunities for applications involving protein structure prediction and de novo protein design. Until recently, the majority of loop modeling methods have been developed and tested by reconstructing loops in frameworks of experimentally resolved structures. In many practical applications, however, the protein loops to be modeled are located in inaccurate structural environments. These include loops in model structures, low-resolution experimental structures, or experimental structures of different functional forms. Accordingly, discrepancies in the accuracy of the structural environment assumed in development of the method and that in practical applications present additional challenges to modern loop modeling methods. This study demonstrates a new strategy for employing a hybrid energy function combining physics-based and knowledge-based components to help tackle this challenge. The hybrid energy function is designed to combine the strengths of each energy component, simultaneously maintaining accurate loop structure prediction in a high-resolution framework structure and tolerating minor environmental errors in low-resolution structures. A loop modeling method based on global optimization of this new energy function is tested on loop targets situated in different levels of environmental errors, ranging from experimental structures to structures perturbed in backbone as well as side chains and template-based model structures. The new method performs comparably to force field-based approaches in loop reconstruction in crystal structures and better in loop prediction in inaccurate framework structures. This result suggests that higher-accuracy predictions would be possible for a broader range of applications. The web server for this method is available at http://galaxy.seoklab.org/loop with the PS2 option for the scoring function.

  6. Inverting reflections using full-waveform inversion with inaccurate starting models

    KAUST Repository

    AlTheyab, Abdullah

    2015-08-19

    We present a method for inverting seismic reflections using full-waveform inversion (FWI) with inaccurate starting models. For a layered medium, near-offset reflections (with zero angle of incidence) are unlikely to be cycle-skipped regardless of the low-wavenumber velocity error in the initial models. Therefore, we use them as a starting point for FWI, and the subsurface velocity model is then updated during the FWI iterations using reflection wavepaths from varying offsets that are not cycle-skipped. To enhance low-wavenumber updates and accelerate the convergence, we take several passes through the non-linear Gauss-Seidel iterations, where we invert traces from a narrow range of near offsets and finally end at the far offsets. Every pass is followed by applying smoothing to the cumulative slowness update. The smoothing is strong at the early stages and relaxed at later iterations to allow for a gradual reconstruction of the subsurface model in a multiscale manner. Applications to synthetic and field data, starting from inaccurate models, show significant low-wavenumber updates and flattening of common-image gathers after many iterations.

  7. Inverse Tasks In The Tsunami Problem: Nonlinear Regression With Inaccurate Input Data

    Science.gov (United States)

    Lavrentiev, M.; Shchemel, A.; Simonov, K.

    A variant of modified training functional that allows considering inaccurate input data is suggested. A limiting case when a part of input data is completely undefined, and, therefore, a problem of reconstruction of hidden parameters should be solved, is also considered. Some numerical experiments are presented. It is assumed that a dependence of known output variables on known input ones should be found is the classic problem definition, which is widely used in the majority of neural nets algorithms. The quality of approximation is evaluated as a performance function. Often the error of the task is evaluated as squared distance between known input data and predicted data multiplied by weighed coefficients. These coefficients may be named "precision coefficients". When inputs are not known exactly, natural generalization of performance function is adding member that responsible for distance between known inputs and shifted inputs, which lessen model's error. It is desirable that the set of variable parameters is compact for training to be con- verging. In the above problem it is possible to choose variants of demands of a priori compactness, which allow meaningful interpretation in the smoothness of the model dependence. Two kinds of regularization was used, first limited squares of coefficients responsible for nonlinearity and second limited multiplication of the above coeffi- cients and linear coefficients. Asymptotic universality of neural net ability to approxi- mate various smooth functions with any accuracy by increase of the number of tunable parameters is often the base for selecting a type of neural net approximation. It is pos- sible to show that used neural net will approach to Fourier integral transform, which approximate abilities are known, with increasing of the number of tunable parameters. In the limiting case, when input data is set with zero precision, the problem of recon- struction of hidden parameters with observed output data appears. The

  8. The results of experimental studies of VLF–ULF electromagnetic emission by rock samples due to mechanical action

    OpenAIRE

    A. A. Panfilov

    2013-01-01

    The paper presents the results of laboratory experiments on electromagnetic emission excitation (electric component of electromagnetic field) by rock samples due to different forms of mechanical stress applications. It was shown that samples generate electric impulses with different spectra when the impact action, gradual loading or dynamic friction is applied. It was ascertained that level and spectral compositions of signals, generated by rock samples, cha...

  9. Angelman Syndrome due to familial translocation: unexpected additional results characterized by Microarray-based Comparative Genomic Hybridization.

    Science.gov (United States)

    Yokoyama-Rebollar, Emiy; Ruiz-Herrera, Adriana; Lieberman-Hernández, Esther; Del Castillo-Ruiz, Victoria; Sánchez-Sandoval, Silvia; Ávila-Flores, Silvia M; Castrillo, José Luis

    2015-01-01

    The 15q11q13 region is subject to imprinting and is involved in various structural rearrangements. Less than 1% of Angelman Syndrome patients are due to translocations involving 15q11q13. These translocations can arise de novo or result from the segregation of chromosomes involved in a familial balanced translocation. A 5-year-old Mexican girl presented with developmental delay, minor dysmorphic features and history of exotropia. G-banding chromosome analysis established the diagnosis of Angelman Syndrome resulting from a familial translocation t(10;15) involving the 15q11.2 region. The available family members were studied using banding and molecular cytogenetic techniques, including Microarray-based Comparative Genomic Hybridization, which revealed additional unexpected results: a coincidental and smaller 15q deletion, asymptomatic duplications in 15q11.2 and Xp22.31 regions. This report demonstrates the usefulness of array CGH for a detailed characterization of familial translocations, including the detection of submicroscopic copy number variations, which would otherwise be missed by karyotype analysis alone. Our report also expands two molecularly characterized rare patient cohorts: Angelman Syndrome patients due to familial translocations and patients with 15q11.2 duplications of paternal origin.

  10. Study of fossil tracks due to 50<=Z<=92 galactic cosmic ray nuclei in meteoritic crystals: Results and perspectives

    CERN Document Server

    Perelygin, V P; Stetsenko, S G; Brandt, R; Vater, P; Rebetez, M; Spohr, R; Vetter, J; Perron, C

    1999-01-01

    A new approach to the problem of investigation of charge and energy spectra of ultra heavy Galactic cosmic ray nuclei, based on fossil track study of extraterrestrial olivine crystals has been developed. The results of an investigation of ultra heavy Galactic cosmic ray nuclei (Z=50-92) in meteoritic olivine crystals are presented. The technique was based on calibration of olivine crystals with accelerated Xe, Au, Pb and U ions and well-controlled partial annealing of 'fresh' and 'fossil' tracks. It allows us to determine the charge spectra and abundances of cosmic ray nuclei based on fossil track length study in meteoritic and Moon crystals. The comparative studies of the spectra of ''fossil' tracks and tracks due to sup 2 sup 0 sup 8 Pb and sup 2 sup 3 sup 8 U nuclei have shown that the group of 210 mu m 'fossil' tracks, first observed in 1980 at JINR is due to Th-U nuclei-products of recent r-process nucleosyntesis in our Galaxy. The method in principle allows one to resolve Pt-Pb peaks in fossil tracks, t...

  11. Rare erroneous results on the Siemens Dimension Vista® platform due to urine carryover: A warning to current users.

    Science.gov (United States)

    Karger, Amy B; Senn, Christine; Skogseth, Kathy; Floodman, Stacy

    2016-07-01

    In 2014, the West Bank Laboratory at the University of Minnesota, part of the non-profit Fairview Health Services system, went live with two Siemens Dimension Vista® 500 instruments. In the first few months after go-live, the lab began receiving reports of rare, erroneous results from clinicians. After further investigation it was noted that most of the errors being reported followed a consistent pattern with significantly elevated potassium, BUN and creatinine. After months of unsuccessful troubleshooting with Siemens, our lab and others within the Fairview Health Services system began hypothesizing that urine carryover was occurring due to the pattern of elevated analytes, and asked Siemens to investigate this hypothesis. In March 2016 Siemens confirmed a software defect which omits an aliquot probe rinse resulting in sample carryover in rare cases. Our objective is to alert current users of the Siemens Dimension Vista® instruments to this rare but alarming phenomenon, discuss the frequency and impact of the erroneous results at our institution, and detail recommended steps for users of Siemens Dimension Vista® instruments to help retrospectively determine whether they have experienced similar erroneous results. Copyright © 2016 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  12. Disruption of SPT23 results in increased heat sensitivity due to plasma membrane damage in Pichia pastoris.

    Science.gov (United States)

    Zhang, Meng; Yu, Qilin; Xiao, Chenpeng; Zhang, Kai; Zhang, Dan; Zhang, Biao; Li, Mingchun

    2018-02-13

    The ability to adapt to environmental changes is the necessary strategy of cell survival. Spt23 is responsible for regulation of Δ-9 desaturase expression in Pichia pastoris. Disruption of SPT23 leads to a remarkable decrease in cellular unsaturated fatty acids. In this study, we found that deletion of SPT23 resulted in growth defect under high temperature culture conditions and heat treatment induced the expression of SPT23. By measuring expression changes of heat shock proteins, protein levels and cellular localization of Hsf1, it revealed that the sensitivity of spt23Δ to high temperature was independent of heat shock response. Addition of the osmotic stabilizer sorbitol can restore the growth defects of spt23Δ under heat condition. In addition, loss of SPT23 led to increased plasma membrane permeability, decreased plasma membrane integrity, depolarization, ergosterol synthesis defect and cell wall component disorder, which suggested that the sensitivity to heat treatment in spt23Δ was due to plasma membrane damage. Taken together, our results give new insights into the relationship between Spt23 and high temperature environmental stress. © FEMS 2018. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  13. The Thirty Years’ Results of Radiation Hygienic Monitoring of Tula Region territories contaminated due to the Chernobyl NPP accident

    Directory of Open Access Journals (Sweden)

    V. V. Boldyreva

    2016-01-01

    Full Text Available Over 50% of Tula Region areas were contaminated after the Chernobyl NPP accident. The article provides the thirty years’ results of radiation hygienic monitoring of the Chernobyl accidental fallout - affected areas in Tula Region. The radiation situation is assessed at the initial accidental period and at the current stage. The initial levels of gamma - radiation dose intensity (up to 35 mcSv/hr are identified for the period of the “iodine” hazard along with the tabular data on the dose intensity relative stabilization by the beginning of August 1986 due to iodine-131 decay. The information is presented regarding iodine-131 tentative maximum permissible level exceedance in the dairy products of the two most contaminated regional areas - Plavskoye and Arsenievskoye. The article also provides the laboratory data on the total beta - activity in the foodstuffs in 1986-1987 and cesium-137 maximum permissible level exceedence in 1986. The radionuclide maximum permissible level exceedances in foodstuffs were registered only in 1986 due to the plants surface contamination whereas in the forest mushrooms those exceedances were repeatedly found until 2004. The black earths and grey forest soils had a benign impact upon the intensity of the radionuclide transfer into plants which resulted in the formation of internal radiation doses.At the current stage, the content of cesium-137 and strontium- 90 in the foodstuffs can only be quantified by a radiochemical method. The table covers all the districts within the boundaries of radiation contaminated zones. The radiochemical studies indicate the main dose - forming products. The article contains the table of internal and external radiation doses of the population in Plavsk town over 1986-1990 and displays the factors impacting population’s internal and external exposure. The Chernobyl - affected exposure dose of the population is mostly attributed to the external radiation and, for over twenty years, it

  14. An Alternative Flight Software Trigger Paradigm: Applying Multivariate Logistic Regression to Sense Trigger Conditions Using Inaccurate or Scarce Information

    Science.gov (United States)

    Smith, Kelly M.; Gay, Robert S.; Stachowiak, Susan J.

    2013-01-01

    In late 2014, NASA will fly the Orion capsule on a Delta IV-Heavy rocket for the Exploration Flight Test-1 (EFT-1) mission. For EFT-1, the Orion capsule will be flying with a new GPS receiver and new navigation software. Given the experimental nature of the flight, the flight software must be robust to the loss of GPS measurements. Once the high-speed entry is complete, the drogue parachutes must be deployed within the proper conditions to stabilize the vehicle prior to deploying the main parachutes. When GPS is available in nominal operations, the vehicle will deploy the drogue parachutes based on an altitude trigger. However, when GPS is unavailable, the navigated altitude errors become excessively large, driving the need for a backup barometric altimeter to improve altitude knowledge. In order to increase overall robustness, the vehicle also has an alternate method of triggering the parachute deployment sequence based on planet-relative velocity if both the GPS and the barometric altimeter fail. However, this backup trigger results in large altitude errors relative to the targeted altitude. Motivated by this challenge, this paper demonstrates how logistic regression may be employed to semi-automatically generate robust triggers based on statistical analysis. Logistic regression is used as a ground processor pre-flight to develop a statistical classifier. The classifier would then be implemented in flight software and executed in real-time. This technique offers improved performance even in the face of highly inaccurate measurements. Although the logistic regression-based trigger approach will not be implemented within EFT-1 flight software, the methodology can be carried forward for future missions and vehicles.

  15. An Alternative Flight Software Paradigm: Applying Multivariate Logistic Regression to Sense Trigger Conditions using Inaccurate or Scarce Information

    Science.gov (United States)

    Smith, Kelly; Gay, Robert; Stachowiak, Susan

    2013-01-01

    In late 2014, NASA will fly the Orion capsule on a Delta IV-Heavy rocket for the Exploration Flight Test-1 (EFT-1) mission. For EFT-1, the Orion capsule will be flying with a new GPS receiver and new navigation software. Given the experimental nature of the flight, the flight software must be robust to the loss of GPS measurements. Once the high-speed entry is complete, the drogue parachutes must be deployed within the proper conditions to stabilize the vehicle prior to deploying the main parachutes. When GPS is available in nominal operations, the vehicle will deploy the drogue parachutes based on an altitude trigger. However, when GPS is unavailable, the navigated altitude errors become excessively large, driving the need for a backup barometric altimeter to improve altitude knowledge. In order to increase overall robustness, the vehicle also has an alternate method of triggering the parachute deployment sequence based on planet-relative velocity if both the GPS and the barometric altimeter fail. However, this backup trigger results in large altitude errors relative to the targeted altitude. Motivated by this challenge, this paper demonstrates how logistic regression may be employed to semi-automatically generate robust triggers based on statistical analysis. Logistic regression is used as a ground processor pre-flight to develop a statistical classifier. The classifier would then be implemented in flight software and executed in real-time. This technique offers improved performance even in the face of highly inaccurate measurements. Although the logistic regression-based trigger approach will not be implemented within EFT-1 flight software, the methodology can be carried forward for future missions and vehicles

  16. Prevalence of visual impairment due to uncorrected refractive error: Results from Delhi-Rapid Assessment of Visual Impairment Study.

    Science.gov (United States)

    Senjam, Suraj Singh; Vashist, Praveen; Gupta, Noopur; Malhotra, Sumit; Misra, Vasundhara; Bhardwaj, Amit; Gupta, Vivek

    2016-05-01

    To estimate the prevalence of visual impairment (VI) due to uncorrected refractive error (URE) and to assess the barriers to utilization of services in the adult urban population of Delhi. A population-based rapid assessment of VI was conducted among people aged 40 years and above in 24 randomly selected clusters of East Delhi district. Presenting visual acuity (PVA) was assessed in each eye using Snellen's "E" chart. Pinhole examination was done if PVA was refractive error were recorded with questionnaires. Of 2421 individuals enumerated, 2331 (96%) individuals were examined. Females were 50.7% among them. The mean age of all examined subjects was 51.32 ± 10.5 years (standard deviation). VI in either eye due to URE was present in 275 individuals (11.8%, 95% confidence interval [CI]: 10.5-13.1). URE was identified as the most common cause (53.4%) of VI. The overall prevalence of VI due to URE in the study population was 6.1% (95% CI: 5.1-7.0). The elder population as well as females were more likely to have VI due to URE (odds ratio [OR] = 12.3; P prevalence of VI due to URE among the urban adult population of Delhi is still high despite the availability of abundant eye care facilities. The majority of reported barriers are related to human behavior and attitude toward the refractive error. Understanding these aspects will help in planning appropriate strategies to eliminate VI due to URE.

  17. Hypo - and hypernatremia results in inaccurate Erythrocytes mean Corpuscular Volume (MCV) measurement in vitro, when using Sysmex XE 2100

    DEFF Research Database (Denmark)

    Madsen, Kirsten Vikkelsø; Philipsen, Jens Peter

    Introduction: Automated hematology analyzers dilute patient erythrocytes with an isosmotic diluent before quantitating the erythrocyte Mean Cell Volume (MCV). However, if patient plasma osmolality differs from the diluent, water will cross the erythrocytes membrane and establish a new equilibrium...

  18. [Days out of role due to common mental and physical disorders: French results from the WHO World Mental Health surveys].

    Science.gov (United States)

    Icick, R; Kovess, V; Gasquet, I; Lépine, J-P

    2014-09-01

    The burden of health problems, including mental disorders, can be assessed in several ways such as through healthcare costs or loss of productivity. Their impact on daily activities as a whole has received much less attention, especially in France. Therefore, we undertook the analysis of the French general population data from the World Mental Health (WMH) surveys promoted by the World Health Organization (WHO) assessing the number of days out of role due to common mental and physical disorders. Face-to-face interviews were carried out with 2894 respondents (45.9% pooled response rate). Presence of ten chronic physical disorders and nine mental disorders was assessed for each respondent along with information about the number of days in the past month each respondent reported being totally unable to work or carry out their other normal daily activities because of problems with either physical or mental health. Multiple regression analysis was used to estimate associations of specific conditions and comorbidities with days out of role, after controlling for basic socio-demographics. One thousand four hundred and thirty-six subjects reporting at least one core-symptom of a mental disorder underwent the whole assessment. The mean annual number of days out of role was high among those with at least one mental disorder (24.2±8.3). The population attributable risk proportion (PARP), i.e. the proportion of days out of role that would have been avoided if the considered disorder had remitted, was also estimated. Mental disorders as a whole accounted for 49.5% of the PARP. French data on days out of role from the WHO WMH surveys showed the high burden of mental illness in the general population. These results may have been underestimated, taking into account that subjects who were hospitalized at the time of recruitment, whose disorders might also account for a high proportion of days out of role, could not be assessed with our design. Common health conditions, especially

  19. Multiple Intestinal Erosions as a Result of Hemorrhage due to Parasites: Case Reports and Review of the Literature

    Science.gov (United States)

    Pitanga Lukashok, Hannah; Robles-Jara, Carlos; Robles-Medranda, Carlos

    2011-01-01

    Obscure gastrointestinal bleeding appears to be uncommon in patients with parasites. In spite of that some reports had described this relationship in patients evaluated during capsule endoscopy procedures; the characteristic of the bleeding lesions remains unclear. This paper describes two patients with a massive obscure gastrointestinal bleeding due to ascariasis, using the new capsule endoscopy technology “MiroCam”, describing the characteristic of the lesions found in our patients (observed in a better image quality), and reviewing the literature. PMID:21747648

  20. [Maternal deaths due to infectious cause, results from the French confidential enquiry into maternal deaths, 2010-2012].

    Science.gov (United States)

    Rigouzzo, A; Tessier, V; Zieleskiewicz, L

    2017-12-01

    Over the period 2010-2012, maternal mortality from infectious causes accounted for 5% of maternal deaths by direct causes and 16% of maternal deaths by indirect causes. Among the 22 deaths caused by infection occurred during this period, 6 deaths were attributed to direct causes from genital tract origin, confirming thus the decrease in direct maternal deaths by infection during the last ten years. On the contrary, indirect maternal deaths by infection, from extragenital origin, doubled during the same period, with 16 deaths in the last triennium, dominated by winter respiratory infections, particularly influenza: the 2009-2010 influenza A (H1N1) virus pandemic was the leading cause of indirect maternal mortality by infection during the studied period. The main infectious agents involved in maternal deaths from direct causes were Streptococcus A, Escherichia Coli and Clostridium perfringens: these bacterias were responsible for toxic shock syndrome, severe sepsis, secondary in some cases to cellulitis or necrotizing fasciitis. Of the 6 deaths due to direct infection, 4 were considered avoidable because of inadequate management: delayed or missed diagnosis, delayed or inadequate initiation of a specific medical and/or surgical treatment. Of the 16 indirect maternal deaths due to infection causes, the most often involved infectious agents were influenza A (H1N1) virus and Streptococcus pneumonia with induced purpura fulminans: the absence of influenza vaccination during pregnancy, delayed diagnosis and emergency initiation of a specific treatment, were the main contributory factors to these deaths and their avoidability in 70% of the cases analyzed. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. [Maternal deaths due to gestational trophoblastic diseases, results from the French confidential enquiry into maternal deaths, 2010-2012].

    Science.gov (United States)

    Dreyfus, M

    2017-12-01

    Gestational trophoblastic diseases (GTD) correspond to several entities which all have a common pattern: hypersecretion of human chorionic gondotrophin by trophoblastic hyperplasia. Between 2010 and 2012, there were 4 maternal deaths due to GTD (choriocarcinoma). The ratio of maternal death caused by GTD was 0,16/100,000 living births which was similar to the rate from the 2007-2009 period. These deaths represented 1.6% from the whole maternal mortality and 3.3% of the direct maternal mortality. These four deaths occurred after delivery and the diagnosis of GTD was made between 60 and 180 days in the postpartum period. Two cases seemed to be potentially avoidable. The main causes of suboptimal management were linked to delay either in diagnosis of GTD or in initiating the appropriate treatment. The analysis of these maternal deaths gave the opportunity to stress some major lessons to optimize medical management of GTD. Therefore, a patient presenting with persistent bleedings more than six weeks after delivery needs some specific exams such as plasma human chorionic gondotrophin measurement and histopathologic examination to affirm GTD and start early specific treatments generally leading to complete recovery. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  2. [Tactics and results of treatment of acute hemorrhage in gastroduodenal erosive ulcers due to application of gastro-aggressive preparations].

    Science.gov (United States)

    Shapryns'kyĭ, V O; Romanchuk, V D; Koval', V M

    2014-09-01

    Results of treatment of 238 patients, suffering an acute gastrointestinal hemorrhage, occurring on background of application of medicinal preparations, were adduced. The incidence rate for an acute medicinal ulcers of foregut was analyzed, as well as possibilities for their treatment.

  3. False Immunohistochemical Results for Herpesviridae and Other Clusters of Differentiation Due To Biotin Intranuclear Inclusions in the Gestational Endometrium

    Directory of Open Access Journals (Sweden)

    Francesco Rivasi

    2014-02-01

    Conclusions. Immunohistochemical investigations of the gestational endometrium (particularly in pregnancies near to term may yield false results for several herpes viruses, as well as for other immunohistochemical reactions obtained using the ABC method without prior biotin inactivation. [J Interdiscipl Histopathol 2014; 2(1.000: 32-37

  4. Variation in LCA results for disposable polystyrene beverage cups due to multiple data sets and modelling choices

    NARCIS (Netherlands)

    Harst, van der E.J.M.; Potting, J.

    2014-01-01

    Life Cycle Assessments (LCAs) of the same products often result in different, sometimes even contradictory outcomes. Reasons for these differences include using different data sets and deviating modelling choices. This paper purposely used different data sets and modelling choices to identify how

  5. Significance of pregnancy test false negative results due to elevated levels of β-core fragment hCG.

    Science.gov (United States)

    Johnson, Sarah; Eapen, Saji; Smith, Peter; Warren, Graham; Zinaman, Michael

    2017-01-01

    Very high levels of β-core fragment human chorionic gonadotrophin (βcf-hCG) are reported to potentially cause false negative results in point-of-care (POC)/over-the-counter (OTC) pregnancy tests. To investigate this further, women's daily early morning urine samples, collected prior to conception and during pregnancy, were analysed for intact, free β-, and βcf-hCG. The proportion of βcf-hCG was found to be related to that of hCG produced and in circulation. Therefore, best practice for accuracy testing of POC/OTC pregnancy tests would be to test devices against clinical samples containing high levels of βcf-hCG as well as standards spiked with biologically relevant ratios.

  6. Management of gastrointestinal mucositis due to cancer therapies in pediatric patients: results of a case series with SAMITAL(®).

    Science.gov (United States)

    Bertoglio, Juan Carlos; Folatre, Isabel; Bombardelli, Ezio; Riva, Antonella; Morazzoni, Paolo; Ronchi, Massimo; Petrangolini, Giovanna

    2012-11-01

    Gastrointestinal mucositis is a common debilitating complication of chemotherapy and one for which there is currently no effective long-term treatment. To report our experience with the use of SAMITAL(®), a new oral suspension formulation based on the combination of three standardized extracts from Vaccinium myrtillus, Macleaya cordata fruits and Echinacea angustifolia roots in the prevention and treatment of chemotherapy-induced gastrointestinal mucositis in pediatric patients. 20 pediatric patients undergoing chemotherapy for a range of oncological conditions were followed. Patients initially received oral SAMITAL(®) to treat gastrointestinal mucositis and were then given SAMITAL(®) prophylactically to prevent recurrences with successive cycles of chemotherapy. SAMITAL(®) significantly decreased gastrointestinal mucositis grade after the first episode with a reduction of mean scores from 3.2 ± 0.7 at baseline to 0.4 ± 0.6 at the end of treatment (p patients' overall condition and quality of life after the first administration and lowered the need for parenteral nutrition. Importantly, it allowed chemotherapy cycles to be continued without complications. Results from this case series suggest that SAMITAL(®) may play an important role in the prevention and treatment of chemotherapy-induced gastrointestinal mucositis in children and adolescents and as such warrants investigation in controlled studies.

  7. Location-based Mobile Relay Selection and Impact of Inaccurate Path Loss Model Parameters

    DEFF Research Database (Denmark)

    Nielsen, Jimmy Jessen; Madsen, Tatiana Kozlova; Schwefel, Hans-Peter

    2010-01-01

    by simulations. The SNR measurement based relay selection scheme proposed previously is unsuitable for use with fast moving users in e.g. vehicular scenarios due to a large signaling overhead. The proposed location based scheme is shown to work well with fast moving users due to a lower signaling overhead....... The required location accuracy was found to be comparable to the accuracy of standard GPS. As the scheme was found to be highly sensitive to NLOS situations with unknown attenuation, knowledge of obstacle locations obtained either by sensing online or from a map of obstacles, was identified as a prerequisite...... to be wide enough to allow them to be estimated in practical systems....

  8. Common errors and clinical guidelines for manual muscle testing: "the arm test" and other inaccurate procedures

    Directory of Open Access Journals (Sweden)

    Cuthbert Scott C

    2008-12-01

    Full Text Available Abstract Background The manual muscle test (MMT has been offered as a chiropractic assessment tool that may help diagnose neuromusculoskeletal dysfunction. We contend that due to the number of manipulative practitioners using this test as part of the assessment of patients, clinical guidelines for the MMT are required to heighten the accuracy in the use of this tool. Objective To present essential operational definitions of the MMT for chiropractors and other clinicians that should improve the reliability of the MMT as a diagnostic test. Controversy about the usefulness and reliability of the MMT for chiropractic diagnosis is ongoing, and clinical guidelines about the MMT are needed to resolve confusion regarding the MMT as used in clinical practice as well as the evaluation of experimental evidence concerning its use. Discussion We expect that the resistance to accept the MMT as a reliable and valid diagnostic tool will continue within some portions of the manipulative professions if clinical guidelines for the use of MMT methods are not established and accepted. Unreliable assessments of this method of diagnosis will continue when non-standard MMT research papers are considered representative of the methods used by properly trained clinicians. Conclusion Practitioners who employ the MMT should use these clinical guidelines for improving their use of the MMT in their assessments of muscle dysfunction in patients with musculoskeletal pain.

  9. Heritability of slow and/or inaccurate reading ability in 33,000 adult twins with self-reported data

    DEFF Research Database (Denmark)

    Fibiger-Dagnæs, Steen; von Bornemann Hjelmborg, Jacob; Erbs, Lena

    2012-01-01

    Genetic influence for adult slow and/or inaccurate reading ability was studied from selfreported answers, using a dichotomous question on having difficulties in reading the Danish subtitles on foreign TV programs. The data from 33,424 twins were population based and were used for biometric analysis...... in order to estimate the heritability of reading difficulties. The rate of reading difficulties were 6–9 percent, higher for males than females. Tetrachoric correlations were estimated under univariate saturated models, specified with appropriate constraints. Hierarchical x2 tests showed that the fit...... demonstrates substantial genetic, almost only additive, influence on reading difficulties. The environmental factors affecting reading difficulties were unique and unshared (E). Unshared environmental factors are those factors that are specific to an individual, thus contributing to differences between family...

  10. Immunohistochemical expression of HER2 in breast cancer: socioeconomic impact of inaccurate tests.

    Science.gov (United States)

    Vyberg, Mogens; Nielsen, Søren; Røge, Rasmus; Sheppard, Beth; Ranger-Moore, Jim; Walk, Eric; Gartemann, Juliane; Rohr, Ulrich-Peter; Teichgräber, Volker

    2015-08-29

    Treatment for patients with breast cancer (BC) is guided by human epidermal growth factor receptor 2 (HER2) status. The patient's HER2 status is assessed using US Food and Drug Administration-approved in vitro diagnostic (IVD) immunohistochemical (IHC) tests and laboratory-developed IVD tests. We analysed HER2 testing accuracy using data from the Nordic Immunohistochemistry Quality Control (NordiQC) HER2 IHC programme; results were used in an economic BC treatment model. Data were obtained from NordiQC HER2 BC surveys performed from 2008 to 2012. False-negative (FN) and false-positive (FP) rates for approved and laboratory-developed IVDs were used to estimate direct costs, loss of survival, productivity benefit and quality-adjusted life-years. In the absence of consistent and accessible clinical and economic data from countries participating in the NordiQC programme, United States productivity data, healthcare costs and patient numbers were used as a surrogate in order to estimate the potential impact of selecting an approved or laboratory-developed IVDs. In total, 1703 tests were performed. Pooled FN rates were 11% for approved IVDs and 25% for laboratory-developed IVDs; FP rates were 0% and 5%, respectively. Using these FP and FN rates in the economic model and applying them to the United States BC population, approved IVD tests would result in better clinical outcomes, i.e., better survival and fewer disease recurrences/progressions, and lower costs, i.e., total direct costs and lost productivity, versus laboratory-developed IVD tests. Every $1 saved by laboratories by using cheaper reagents could potentially result in approximately $6 additional costs to the healthcare system. The results of this analysis suggest that incorrect HER2 test results have far-reaching clinical and economic consequences.

  11. Inaccurate weight perception is associated with extreme weight-management practices in U.S. high school students.

    Science.gov (United States)

    Ibrahim, Chadi; El-Kamary, Samer S; Bailey, Jason; St George, Diane M

    2014-03-01

    The objective of the present study was to examine whether adolescents' weight perception accuracy (WPA) was associated with extreme weight-management practices (EWPs) in differing body mass index (BMI) categories. WPA, overassessment, and underassessment were determined by comparing self-reported BMI and weight perception among U.S. high school students in the 2009 National Youth Risk Behavior Survey. BMI was classified as follows: underweight (perception were discordant. Overassessors thought they were heavier than they were (among underweight/healthy groups); underassessors thought they were lighter than they were (among healthy/overweight/obese groups). EWPs included ≥1 of fasting, use of diet pills, or purging/laxative use. Logit models were fitted for different BMI sex strata. In the final sample of 14,722 US high school students with complete data, 20.2%, 85.7%, 5.8%, and 80.9% of those who were underweight, healthy weight, overweight, and obese, inaccurately assessed their weight, respectively. In turn, 11.4% and 17.6% of accurate and inaccurate assessors engaged in EWPs, respectively. After adjustment, underweight girls who overassessed their weight had 12.6 times higher odds of EWPs (95% confidence interval 3.4-46.6). Moreover, there were elevated odds of EWPs among healthy weight students who overassessed their weight. Overassessing healthy weight students and underweight girls had higher odds of ≥1 EWPs, likely related to an unhealthy desire to lose weight. The present study demonstrates a need to further educate clinicians on WPA and its relation to EWPs even among those of healthy weight who may be seen as not at risk.

  12. FALSE, INACCURATE AND INCOMPLETE NEWS: CHALLENGES FACING JOURNALISTS INVOLUNTARY RECTIFICATION. THE SPANISH EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Ángeles Fernández Barrero

    2013-06-01

    Full Text Available Journalists must verify information provided by their sources. However, factors such as job precariousness, urgency and the credibility they give to mainly institutional sources mean that journalists do not verify information. Most codes of conduct recommend the duty to correct information as soon as an unintentionally committed error is discovered, but journalists dislike recognising their own errors and even more so correcting them publicly. These circumstances affect adversely the quality of discourse and the credibility of mass-media. Ombudsmen partially bridge this gap. As a result, false, mistaken, wrong or biased pieces of news are published and journalists, against the rules of truth and honesty, rarely rectify on their own initiative. This article analyses the coverage of Iraq’s weapons of mass destruction, in which the game of mimicry saw the same mistake repeated in different media and in different countries, although prestigious newspapers published an unusual public apology.

  13. False, inaccurate and incomplete news: challenges facing journalists involuntary rectification. The Spanish experience

    Directory of Open Access Journals (Sweden)

    Antonio López Hidalgo

    2012-12-01

    Full Text Available Journalists must verify information provided by their sources. However, factors such as job precariousness, urgency and the credibility they give to mainly institutional sources mean that journalists do not verify information. Most codes of conduct recommend the duty to correct information as soon as an unintentionally committed error is discovered, but journalists dislike recognising their own errors and even more so correcting them publicly. These circumstances affect adversely the quality of discourse and the credibility of mass-media. Ombudsmen partially bridge this gap. As a result, false, mistaken, wrong or biased pieces of news are published and journalists, against the rules of truth and honesty, rarely rectify on their own initiative. This article analyses the coverage of Iraq’s weapons of mass destruction, in which the game of mimicry saw the same mistake repeated in different media and in different countries, although prestigious newspapers published an unusual public apology.

  14. Oral and Tympanic Membrane Temperatures are Inaccurate to Identify Fever in Emergency Department Adults

    Directory of Open Access Journals (Sweden)

    Robert Silverman

    2011-05-01

    Full Text Available Introduction: Identifying fever can influence management of the emergency department (ED patient, including diagnostic testing, treatment, and disposition. We set out to determine how well oral and tympanic membrane (TM temperatures compared with rectal measurements. Methods: A convenience sample of consecutively adult ED patients had oral, TM, and rectal temperatures performed within several minutes of each other. Descriptive statistics, Bland–Altman agreement matrices with 95% confidence interval (CI, and measures of test performance, including sensitivity, specificity, predictive values, and interval likelihood ratios were performed. Results: A total of 457 patients were enrolled with an average age of 64 years (standard deviation: 19 years. Mean temperatures were: oral (98.38F, TM (99.68F, and rectal (99.48F. The mean difference in rectal and oral temperatures was 1.18F, although there was considerable lack of agreement between oral and rectal temperatures, with the oral temperature as much as 2.918F lower or 0.748F higher than the rectal measurement (95% CI. Although the difference in mean temperature between right TM and rectal temperature was only 0.228F, the right TM was lower than rectal by up to 1.618F or greater by up to 2.058F (95% CI. Test performance varied as the positive predictive value of the oral temperature was 97% and for tympanic temperature was 55% (relative to a rectal temperature of 100.48F or higher. Comparative findings differed even at temperatures considered in the normal range; among patients with an oral temperature of 98.0 to 98.9, 38% (25/65 were found to have a rectal temperature of 100.4 or higher, while among patients with a TM of 98.0 to 98.9, only 7% (10/134 were found to have a rectal temperature of 100.4 or higher. Conclusion: In conclusion, the oral and tympanic temperature readings are not equivalent to rectal thermometry readings. Oral thermometry frequently underestimates the temperature relative to

  15. Healthcare utilization and lost productivity due to infectious gastroenteritis, results from a national cross-sectional survey Australia 2008-2009.

    Science.gov (United States)

    Chen, Y; Ford, L; Hall, G; Dobbins, T; Kirk, M

    2016-01-01

    The aim of this study was to estimate the healthcare usage and loss of productivity due to gastroenteritis in Australia using the National Gastroenteritis Survey II. In 2008-2009, 7578 participants across Australia were surveyed about infectious gastroenteritis by telephone interview. A gastroenteritis case was defined as a person experiencing ⩾ 3 loose stools and/or ⩾ 2 vomits in a 24-h period, excluding cases with a non-infectious cause for their symptoms, such as pregnancy or consumption of alcohol. Lost productivity was considered any lost time from full- or part-time paid work due to having gastroenteritis or caring for someone with the illness. Interference with other daily activities was also examined along with predictors of healthcare-seeking practices using multivariable regression. Results were weighted to obtain nationally representative estimates using Stata v. 13·1. Of the 341 cases, 52 visited a doctor due to gastroenteritis, 126 reported taking at least one medication for their symptoms and 79 cases reported missing ⩾ 1 days' paid work due to gastroenteritis. Gastroenteritis results in a total of 13·1 million (95% confidence interval 6·7-19·5) days of missed paid work each year in Australia. The indirect costs of gastroenteritis are significant, particularly from lost productivity.

  16. Perceived organizational justice as a predictor of long-term sickness absence due to diagnosed mental disorders: results from the prospective longitudinal Finnish Public Sector Study.

    Science.gov (United States)

    Elovainio, Marko; Linna, Anne; Virtanen, Marianna; Oksanen, Tuula; Kivimäki, Mika; Pentti, Jaana; Vahtera, Jussi

    2013-08-01

    Organizational justice perceptions have been suggested to be associated with symptoms of mental health but the nature of the association is unknown due to reporting bias (measurement error related to response style and reversed causality). In this study, we used prospective design and long-term (>9 days) sickness absence with psychiatric diagnosis as the outcome measure. Participants were 21,221 Finnish public sector employees (the participation rate at baseline in 2000-2002 68%), who responded to repeated surveys of procedural and interactional justice in 2000-2004 along with register data on sickness absence with a diagnosis of depression or anxiety disorders (822 cases). Results from logistic regression analyses showed that a one-unit increase in self-reported and work-unit level co-worker assessed interactional justice was associated with a 25-32% lower odds of sickness absence due to anxiety disorders. These associations were robust to adjustments for a variety of potential individual-level confounders including chronic disease (adjusted OR for self-reported interactional justice 0.77, 95% CI 0.65-0.91) and were replicated using co-worker assessed justice. Only weak evidence of reversed causality was found. The results suggest that low organizational justice is a risk factor for sickness absence due to anxiety disorders. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. [Social Determinants of Subjective Health, Life Satisfaction and Absence From School due to Illness Among Adolescents: First results of the German National Educational Panel Study (NEPS)].

    Science.gov (United States)

    Heilmann, Kristina; Bräsen, Janina; Herke, Max; Richter, Matthias; Rathmann, Katharina

    2017-02-16

    The aim of this study is to examine the impact of social determinants on subjective health, life satisfaction and absence from school due to illness among adolescents in secondary schools, by using data from the German National Educational Panel Study (NEPS). Data was obtained from the National Educational Panel Study (NEPS). The sample included (n=5 790) 6 th grade pupils in regular schools in 2011 (Starting Cohort 3, Wave 2). The socioeconomic background of adolescents was measured by pupils' school type as well as household income and parental education level. Family structure and gender were considered as additional social determinants in the analyses. Bivariate and multiple logistic regression techniques were applied. The results show that type of school and low household income were related to poor subjective health among students. Life satisfaction varied by family structure and school type. For absence from school due to illness, we found a weak association with students in low track schools. The results indicate that especially the school type had the most important impact on subjective health, life satisfaction and absence from school due to illness. Health promotion and preventive strategies should particularly focus on pupils in low track schools and in relation to socially unequal distribution of educational opportunities also on young people from households with low socioeconomic status. © Georg Thieme Verlag KG Stuttgart · New York.

  18. In meta-analyses of proportion studies, funnel plots were found to be an inaccurate method of assessing publication bias.

    Science.gov (United States)

    Hunter, James P; Saratzis, Athanasios; Sutton, Alex J; Boucher, Rebecca H; Sayers, Robert D; Bown, Matthew J

    2014-08-01

    To assess the utility of funnel plots in assessing publication bias (PB) in meta-analyses of proportion studies. Meta-analysis simulation study and meta-analysis of published literature reporting peri-operative mortality after abdominal aortic aneurysm (AAA) repair. Data for the simulation study were stochastically generated. A literature search of Medline and Embase was performed to identify studies for inclusion in the published literature meta-analyses. The simulation study demonstrated that conventionally constructed funnel plots (log odds vs. 1/standard error [1/SE]) for extreme proportional outcomes were asymmetric despite no PB. Alternative funnel plots constructed using study size rather than 1/SE showed no asymmetry for extreme proportional outcomes. When used in meta-analyses of the mortality of AAA repair, these alternative funnel plots highlighted the possibility for conventional funnel plots to demonstrate asymmetry when there was no evidence of PB. Conventional funnel plots used to assess for potential PB in meta-analyses are inaccurate for meta-analyses of proportion studies with low proportion outcomes. Funnel plots of study size against log odds may be a more accurate way of assessing for PB in these studies. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. Sample Size Calculation: Inaccurate A Priori Assumptions for Nuisance Parameters Can Greatly Affect the Power of a Randomized Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Elsa Tavernier

    Full Text Available We aimed to examine the extent to which inaccurate assumptions for nuisance parameters used to calculate sample size can affect the power of a randomized controlled trial (RCT. In a simulation study, we separately considered an RCT with continuous, dichotomous or time-to-event outcomes, with associated nuisance parameters of standard deviation, success rate in the control group and survival rate in the control group at some time point, respectively. For each type of outcome, we calculated a required sample size N for a hypothesized treatment effect, an assumed nuisance parameter and a nominal power of 80%. We then assumed a nuisance parameter associated with a relative error at the design stage. For each type of outcome, we randomly drew 10,000 relative errors of the associated nuisance parameter (from empirical distributions derived from a previously published review. Then, retro-fitting the sample size formula, we derived, for the pre-calculated sample size N, the real power of the RCT, taking into account the relative error for the nuisance parameter. In total, 23%, 0% and 18% of RCTs with continuous, binary and time-to-event outcomes, respectively, were underpowered (i.e., the real power was 90%. Even with proper calculation of sample size, a substantial number of trials are underpowered or overpowered because of imprecise knowledge of nuisance parameters. Such findings raise questions about how sample size for RCTs should be determined.

  20. Trends in the incidence of tooth extraction due to periodontal disease: results of a 12-year longitudinal cohort study in South Korea

    Science.gov (United States)

    2017-01-01

    Purpose This study evaluated trends in tooth extraction due to acute and chronic periodontal disease (PD) using data from the National Health Insurance Service-National Sample Cohort for 2002–2013. Methods A random sample of 1,025,340 individuals was selected as a representative sample of the population, and a database (DB) of diagnostic and prescription codes was followed up for 12 years. We used multivariate logistic regression analysis to assess the incidence of total extraction (TE), extraction due to periodontal disease (EPD), and immediate extraction due to periodontal disease (IEPD) according to sociodemographic factors (sex, age, household income, health status, and area of residence). Results The incidence of tooth extraction was found to be increasing, and at a higher rate for TE in PD patients. In 2002, 50.6% of cases of TE were caused by PD, and this increased to 70.8% in 2013, while the number of cases of IEPD increased from 42.8% to 54.9% over the same period. The incidence rates of extraction due to acute and chronic PD increased monotonically. We found that the incidence rates of TE, EPD, and IEPD were all 2-fold higher among patients with high income levels and those who were not beneficiaries of health insurance. Conclusions The rates of TE, EPD, and IEPD have been steadily increasing despite dental healthcare policies to expand public health insurance coverage, increasing the accessibility of dental clinics. Moreover, the effects of these policies were found to vary with both income and education levels. Consistent patient follow-up is required to observe changes in trends regarding tooth extraction according to changes in dental healthcare policies, and meticulous studies of such changes will ensure optimal policy reviews and revisions. PMID:29093985

  1. Prostatic Arterial Embolization with Small Sized Particles for the Treatment of Lower Urinary Tract Symptoms Due to Large Benign Prostatic Hyperplasia: Preliminary Results

    Directory of Open Access Journals (Sweden)

    Qiang Li

    2015-01-01

    Full Text Available Background: The clinical failure after prostatic artery embolization (PAE with conventional particles was relatively high, in treatment for lower urinary tract symptoms (LUTS due to benign prostatic hyperplasia (BPH. We reported the results of PAE with combined polyvinyl alcohol particles 50 μm and 100 μm in size as a primary treatment in 24 patients with severe LUTS secondary to large BPH. Methods: From July 2012 to June 2014, we performed PAE in 24 patients (65-85 years, mean 74.5 years with severe LUTS due to large BPH (≥80 cm 3 and refractory to medical therapy. Embolization was performed using combination of 50 μm and 100 μm in particles size. Clinical follow-up was performed using the International Prostate Symptom Score (IPSS, quality of life (QoL, peak urinary flow (Q max , postvoid residual (PVR volume, the International Index of Erectile Function (IIEF, prostatic specific antigen (PSA, and prostatic volume measured by magnetic resonance imaging at 1, 3, 6, and every 6-month thereafter. Technical success was defined when PAE was completed in at least one pelvic side. Clinical success was defined as the improvement of both symptoms and QoL. A Student′s t-test for paired samples was used. Results: PAE was technically successful in 22 patients (92%. Bilateral PAE was performed in 19 (86% patients and unilateral in 3 (14% patients. Follow-up data were available for 22 patients observed for mean of 14 months. The clinical improvement at 1, 3, 6, and 12-month was 91%, 91%, 88%, and 83%, respectively. At 6-month follow-up, the mean IPSS, QoL, PVR, and Q max were from 27 to 8 (P = 0.001, from 4.5 to 2.0 (P = 0.002, from 140.0 ml to 55.0 ml (P = 0.002, and from 6.0 ml/s to 13.0 ml/s (P = 0.001, respectively. The mean prostate volume decreased from 110 cm 3 to 67.0 cm 3 (mean reduction of 39.1%; P = 0.001. The PSA and IIEF improvements after PAE did not differ from pre-PAE significantly. No major adverse events were noted. Conclusions

  2. Prostatic Arterial Embolization with Small Sized Particles for the Treatment of Lower Urinary Tract Symptoms Due to Large Benign Prostatic Hyperplasia: Preliminary Results

    Science.gov (United States)

    Li, Qiang; Duan, Feng; Wang, Mao-Qiang; Zhang, Guo-Dong; Yuan, Kai

    2015-01-01

    Background: The clinical failure after prostatic artery embolization (PAE) with conventional particles was relatively high, in treatment for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). We reported the results of PAE with combined polyvinyl alcohol particles 50 μm and 100 μm in size as a primary treatment in 24 patients with severe LUTS secondary to large BPH. Methods: From July 2012 to June 2014, we performed PAE in 24 patients (65–85 years, mean 74.5 years) with severe LUTS due to large BPH (≥80 cm3) and refractory to medical therapy. Embolization was performed using combination of 50 μm and 100 μm in particles size. Clinical follow-up was performed using the International Prostate Symptom Score (IPSS), quality of life (QoL), peak urinary flow (Qmax), postvoid residual (PVR) volume, the International Index of Erectile Function (IIEF), prostatic specific antigen (PSA), and prostatic volume measured by magnetic resonance imaging at 1, 3, 6, and every 6-month thereafter. Technical success was defined when PAE was completed in at least one pelvic side. Clinical success was defined as the improvement of both symptoms and QoL. A Student's t-test for paired samples was used. Results: PAE was technically successful in 22 patients (92%). Bilateral PAE was performed in 19 (86%) patients and unilateral in 3 (14%) patients. Follow-up data were available for 22 patients observed for mean of 14 months. The clinical improvement at 1, 3, 6, and 12-month was 91%, 91%, 88%, and 83%, respectively. At 6-month follow-up, the mean IPSS, QoL, PVR, and Qmax were from 27 to 8 (P = 0.001), from 4.5 to 2.0 (P = 0.002), from 140.0 ml to 55.0 ml (P = 0.002), and from 6.0 ml/s to 13.0 ml/s (P = 0.001), respectively. The mean prostate volume decreased from 110 cm3 to 67.0 cm3 (mean reduction of 39.1%; P = 0.001). The PSA and IIEF improvements after PAE did not differ from pre-PAE significantly. No major adverse events were noted. Conclusions: The

  3. Study of fossil tracks due to 50≤Z≤92 galactic cosmic ray nuclei in meteoritic crystals: Results and perspectives

    International Nuclear Information System (INIS)

    Perelygin, V.P.; Petrova, R.I.; Stetsenko, S.G.; Brandt, R.; Vater, P.; Rebetez, M.; Spohr, R.; Vetter, J.; Perron, C.

    1999-01-01

    A new approach to the problem of investigation of charge and energy spectra of ultra heavy Galactic cosmic ray nuclei, based on fossil track study of extraterrestrial olivine crystals has been developed. The results of an investigation of ultra heavy Galactic cosmic ray nuclei (Z=50-92) in meteoritic olivine crystals are presented. The technique was based on calibration of olivine crystals with accelerated Xe, Au, Pb and U ions and well-controlled partial annealing of 'fresh' and 'fossil' tracks. It allows us to determine the charge spectra and abundances of cosmic ray nuclei based on fossil track length study in meteoritic and Moon crystals. The comparative studies of the spectra of ''fossil' tracks and tracks due to 208 Pb and 238 U nuclei have shown that the group of 210 μm 'fossil' tracks, first observed in 1980 at JINR is due to Th-U nuclei-products of recent r-process nucleosyntesis in our Galaxy. The method in principle allows one to resolve Pt-Pb peaks in fossil tracks, to establish the upper limit of the abundance of Z>110 nuclei in the Galactic cosmic rays at the level ≤10 -3 to the abundance of actinide nuclei and to get information on the history of Z>50 cosmic ray nuclei in time interval up to 220 M.Y

  4. Long-Term Evaluation of Patients Undergoing Genitoplasty due to Disorders of Sex Development: Results from a 14-Year Follow-Up

    Directory of Open Access Journals (Sweden)

    Heng Zhang

    2013-01-01

    Full Text Available Purpose. To summarize the experience in treating patients with genitoplasty due to disorders of sex development in China. Methods. The operative procedures, gender of rearing, surgical outcome, and psychosocial and family adjustments of 262 patients were reviewed retrospectively. Results. At initial diagnosis, the mean age was years (range: 2–38 years. There were 96 children, 133 adolescents, and 33 adults. Follow-up was done every 6 months. Patients with female sex assignment had no urinary incontinence or voiding difficulty. Five patients underwent the second surgery (3%; vaginal dilation was performed in 35 patients with postoperative vaginal stenosis; 12 patients (7.4% were unsatisfactory with the outcome. For patients with male sex assignment, the median length of penis was 2.2 cm in prepubertal patients, 4.2 cm in pubertal patients, and 5.0 cm in adults; 39 patients developed postvoid dribbling (39%; 21 patients underwent a second surgery (21%; urethral dilation was done in 28 patients (28% due to urethral stricture; 38 patients were unsatisfactory with the outcome (38%. In addition, 136 patients (83% with female sex assignment and 54 (54% with male sex assignment had favorable psychosocial adjustment. Conclusions. Patients with male sex assignment have more surgical complications and difficulties in psychosocial adjustment as compared to those with female sex assignment.

  5. results

    Directory of Open Access Journals (Sweden)

    Salabura Piotr

    2017-01-01

    Full Text Available HADES experiment at GSI is the only high precision experiment probing nuclear matter in the beam energy range of a few AGeV. Pion, proton and ion beams are used to study rare dielectron and strangeness probes to diagnose properties of strongly interacting matter in this energy regime. Selected results from p + A and A + A collisions are presented and discussed.

  6. Health results of a coup attempt: evaluation of all patients admitted to hospitals in Istanbul due to injuries sustained during the July 15, 2016 coup attempt.

    Science.gov (United States)

    Tayfur, İsmail; Afacan, Mustafa Ahmet; Erdoğan, Mehmet Özgür; Çolak, Şahin; Söğüt, Özgür; Genç Yavuz, Burcu; Bozan, Korkut

    2018-01-01

    A coup attempt against the government took place in Turkey on July 15, 2016. This attempt caused serious injuries and deaths in the country. In this study, the data of patients referred to all hospitals in Istanbul during the attempt were evaluated, and differences between natural disasters, other terrorist actions, and coup attempts were analyzed. In total, 1104 patients were injured in the abovementioned coup attempt. In this study, the demographic and health information of 882 coup victims who were admitted to all hospitals (state and private) in Istanbul on July 15 and 16, 2016 and registered at the Crisis Center of Istanbul Provincial Health Directorate was analyzed. Of the 882 patients evaluated, 97.27% were male and 2.73% were female. The mean age of the patients was 34.12 years. Most (82.43%) patients were admitted to state hospitals, and 17.57% were admitted to private hospitals. The total mortality rate due to the abovementioned coup attempt was 10.4% (9.76% in state hospitals and 13.54% in private hospitals). Of the 882 patients evaluated, 65.07% had gunshot injuries, 11.11% had been assaulted, 7.70% had experienced tank/motor vehicle accidents, 5.44% had other penetrating injuries, 5.32% had soft-tissue trauma, 2.83% had experienced falls (including falls from heights), 0.33% had psychiatric disorders, and 2.15% were admitted for other reasons. The patterns of injury and mortality resulting from the July 15, 2016 coup attempt differed from those resulting from natural disasters and terrorist acts and were similar to those encountered during wars: the victims were predominantly male, similar to those in wars. Following a coup attempt, an increase in the number of patients with post-traumatic stress disorder can be expected. Further studies focusing on the incidence of this disorder due to the abovementioned coup attempt in Turkey are needed. Hospital disaster plans need to include information and plans related to terrorist acts, such as coup attempts.

  7. Cognitive Results of CANTAB Tests and Their Change Due to the First Dose of Donepezil May Predict Treatment Efficacy in Alzheimer Disease.

    Science.gov (United States)

    Kuzmickienė, Jurgita; Kaubrys, Gintaras

    2015-12-14

    BACKGROUND Ability to predict the efficacy of treatment in Alzheimer disease (AD) may be very useful in clinical practice. Cognitive predictors should be investigated alongside with the demographic, genetic, and other predictors of treatment efficacy. The aim of this study was to establish whether the baseline measures of CANTAB tests and their changes due to the first donepezil dose are able to predict the efficacy of treatment after 4 months of therapy. We also compared the predictive value of cognitive, clinical, and demographic predictors of treatment efficacy in AD. MATERIAL AND METHODS Seventy-two AD patients (62 treatment-naïve and 10 donepezil-treated) and 30 controls were enrolled in this prospective, randomized, rater-blinded, follow-up study. Treatment-naïve AD patients were randomized to 2 groups to take the first donepezil dose after the first or second CANTAB testing, separated by 4 hours. Follow-up Test 3 was performed 4 months after the initial assessment. RESULTS The groups were similar in age, education, gender, Hachinski index, and depression. General Regression Models (GRM) have shown that cognitive changes after the first dose of donepezil in PAL (t-values for regression coefficients from 3.43 to 6.44), PRMd (t=4.33), SWM (t=5.85) test scores, and baseline results of PAL (t=2.57-2.86), PRM (t=3.08), and CRT (t=3.42) tests were significant predictors of long-term donepezil efficacy in AD (pdonepezil dose in CANTAB PAL, PRM, and SWM test measures are able to predict the long-term efficacy of donepezil in AD. Baseline PAL, PRM, and CRT test results were significant predictors.

  8. Using a simulation model to assess risk of false negative point-of-care urinary human chorionic gonadotropin device results due to high-dose hook interference.

    Science.gov (United States)

    Milhorn, Denise; Korpi-Steiner, Nichole

    2015-02-01

    It is unclear if the point-of-care (POC) Clinitest hCG device is subject to high-dose hook interference from physiological concentrations of intact human chorionic gonadotropin (hCG), β-core fragment of hCG (hCGβcf), and hCG free β-subunit (hCGβ) found in urine during pregnancy. We used a simulation model to address this question and related our findings to our institution's pregnant population in order to assess risk for potential false-negative hCG results. The expected distribution of days relative to ovulation during routine POC hCG testing was estimated from 182 patients. Clinitest-Clinitek Status hCG device susceptibility to high-dose hook interference from hCG variants and potential risk of false-negative results as it relates to this population were evaluated by testing increasing concentrations of hCG, hCGβcf, hCGβ as well as urine simulating physiological hCG, hCGβcf and hCGβ concentrations expected during early pregnancy (≤44 days post-ovulation). The Clinitest-Clinitek Status hCG device exhibited high-dose hook interference from hCGβcf alone, but not from hCG, hCGβ, or simulated physiological urinary concentrations of combined hCG, hCGβcf and hCGβ expected during early pregnancy. The majority of our patient population had urinary hCG testing conducted during early pregnancy. The Clinitest-Clinitek Status hCG device is unlikely to exhibit false-negative urinary hCG results due to high-dose hook interference for women in early healthy pregnancy, although additional studies are necessary to determine potential risk in other patient populations. Visual interpretation of POC urinary hCG device results is an important failure mode to consider in risk analyses for erroneous urinary hCG device results. Published by Elsevier Inc.

  9. Thyroid exposure of Belarusian and Ukrainian children due to the Chernobyl accident and resulting thyroid cancer risk. Final report of BfS project StSch 4240

    International Nuclear Information System (INIS)

    Jacob, P.; Meckbach, R.; Ulanovski, A.; Schotola, C.; Proehl, G.; Kenigsberg, J.; Buglova, E.; Kruk, J.; Likhtarev, I.; Kovgan, L.; Vavilov, S.; Chepurniy, M.; Tronko, M.; Bogdanova, T.; Shinkarev, S.; Gavrilin, Y.; Demidchik, Y.

    2005-01-01

    Main objectives of the BfS Project StSch4240 Thyroid Exposure of Belarusian and Ukrainian Children due to the Chernobyl Accident and Resulting Thyroid Cancer Risk were: to establish improved estimates of average thyroid dose for both genders and for each birth-year cohort of the period 1968 - 1985 in Ukrainian and Belarusian settlements, in which more than 10 measurements of the 131 I activity in the human thyroid have been performed in May/June 1986, to explore, whether this dosimetric database can be extended to neighboring settlements, to establish improved estimates of average thyroid dose for both genders and for each birth-year cohort of the period 1968 - 1985 in Ukrainian and Belarusian oblasts (regions) and larger cities, to document the thyroid cancer incidence for the period 1986 - 2001 in Ukraine and Belarus and describe morphological characteristics of the cancer cases, to assess the contribution of the baseline incidence to the total thyroid cancer incidence in the two countries and identify regional and temporal dependencies, to perform analyses of excess risks in settlements with more than 10 measurements of the 131 I activity in the human thyroid. The project has been conducted in the period 6 December 1999 to 31 March 2004. (orig.)

  10. Thyroid exposure of Belarusian and Ukrainian children due to the Chernobyl accident and resulting thyroid cancer risk. Final report of BfS project StSch 4240

    Energy Technology Data Exchange (ETDEWEB)

    Jacob, P.; Meckbach, R.; Ulanovski, A.; Schotola, C.; Proehl, G. [GSF-Institute of Radiation Protection, Neuherberg (Germany); Kenigsberg, J.; Buglova, E.; Kruk, J. [Institute of Radiation Medicine and Endocrinology, Minsk (Belarus); Likhtarev, I.; Kovgan, L.; Vavilov, S.; Chepurniy, M. [Ukrainian Radiation Protection Inst., Kyiv (Ukraine); Tronko, M.; Bogdanova, T. [Institute of Endocrinolgoy and Metabolism of the Academy of Medical Sciences of Ukraine, Kyiv (Ukraine); Shinkarev, S.; Gavrilin, Y. [All-Russian Public Organization of Invalids ' Chernobylets' , Scientific Center ' FENIX' , Moscow (Russian Federation); Demidchik, Y. [Thyroid Cancer Center, Minsk (Belarus)

    2005-07-01

    Main objectives of the BfS Project StSch4240 Thyroid Exposure of Belarusian and Ukrainian Children due to the Chernobyl Accident and Resulting Thyroid Cancer Risk were: to establish improved estimates of average thyroid dose for both genders and for each birth-year cohort of the period 1968 - 1985 in Ukrainian and Belarusian settlements, in which more than 10 measurements of the {sup 131}I activity in the human thyroid have been performed in May/June 1986, to explore, whether this dosimetric database can be extended to neighboring settlements, to establish improved estimates of average thyroid dose for both genders and for each birth-year cohort of the period 1968 - 1985 in Ukrainian and Belarusian oblasts (regions) and larger cities, to document the thyroid cancer incidence for the period 1986 - 2001 in Ukraine and Belarus and describe morphological characteristics of the cancer cases, to assess the contribution of the baseline incidence to the total thyroid cancer incidence in the two countries and identify regional and temporal dependencies, to perform analyses of excess risks in settlements with more than 10 measurements of the {sup 131}I activity in the human thyroid. The project has been conducted in the period 6 December 1999 to 31 March 2004. (orig.)

  11. Due diligence

    International Nuclear Information System (INIS)

    Sanghera, G.S.

    1999-01-01

    The Occupational Health and Safety (OHS) Act requires that every employer shall ensure the health and safety of workers in the workplace. Issues regarding the practices at workplaces and how they should reflect the standards of due diligence were discussed. Due diligence was described as being the need for employers to identify hazards in the workplace and to take active steps to prevent workers from potentially dangerous incidents. The paper discussed various aspects of due diligence including policy, training, procedures, measurement and enforcement. The consequences of contravening the OHS Act were also described

  12. Caprine and ovine Greek dairy products: The official German method generates false-positive results due to κ-casein gene polymorphism.

    Science.gov (United States)

    Tsartsianidou, V; Triantafillidou, D; Karaiskou, N; Tarantili, P; Triantafillidis, G; Georgakis, E; Triantafyllidis, A

    2017-05-01

    Caseins are widely used for species identification of dairy products. Isoelectric focusing (IEF) of para-κ-casein peptide is used as the official German method for the differentiation between caprine (isoform A) and ovine (isoform B) dairy products, based on their different isoelectric points. The discrimination between Greek goat and ewe dairy products using IEF has, however, been shown to be problematic because of the existence of the ewe isoform in milk from Greek indigenous dairy goats. This could be due to nucleotide polymorphisms within the goat κ-casein gene of Greek indigenous breeds, which alter the isoelectric point of the para-κ-casein peptide and lead to false positive results. Previous DNA analysis of the goat κ-casein gene has shown high levels of polymorphism; however, no such information is available for Greek indigenous dairy goats. Therefore, 87 indigenous dairy goats were sequenced at exon IV of κ-casein gene. In total, 9 polymorphic sites were detected. Three nonsynonymous point mutations were identified, which change the isoelectric point of the goat para-κ-casein peptide so that it appears identical to that of the ewe peptide. Ten composite genotypes were reconstructed and 6 of them included the problematic point mutations. For the verification of genetic results, IEF was carried out. Both goat and ewe patterns appeared in the problematic genotypes. The frequency of these genotypes could be characterized as moderate (0.23) to high (0.60) within Greek indigenous breeds. However, this is not an issue restricted to Greece, as such genotypes have been detected in various non-Greek goat breeds. In conclusion, IEF based on the official German method is certainly inappropriate for ovine and caprine discrimination concerning Greek dairy goat products, and consequently a new method should be established. Copyright © 2017 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  13. Estimate of the Costs Caused by Adverse Effects in Hospitalised Patients Due to Hip Fracture: Design of the Study and Preliminary Results

    Directory of Open Access Journals (Sweden)

    David Cuesta-Peredo

    2018-02-01

    Full Text Available Introduction: Hip fracture is a health problem that presents high morbidity and mortality, negatively influencing the patient’s quality of life and generating high costs. Structured analysis of quality indicators can facilitate decision-making, cost minimization, and improvement of the quality of care. Methods: We studied 1571 patients aged 70 years and over with the diagnosis of hip fracture at Hospital Universitario de la Ribera in the period between 1 January 2012 and 31 December 2016. Demographic, clinical, functional, and quality indicator variables were studied. An indirect analysis of the costs associated with adverse events arising during hospital admission was made. A tool based on the “Minimum Basic Data Set (CMBD” was designed to monitor the influence of patient risk factors on the incidence of adverse effects (AE and their associated costs. Results: The average age of the patients analysed was 84.15 years (SD 6.28, with a length of stay of 8.01 days (SD 3.32, a mean preoperative stay of 43.04 h (SD 30.81, and a mortality rate of 4.2%. Likewise, the percentage of patients with AE was 41.44%, and 11.01% of patients changed their cost as a consequence of these AEs suffered during hospital admission. The average cost of patients was €8752 (SD: 1,864 and the average cost increase in patients with adverse events was €2321 (SD: 3,164. Conclusions: Through the analysis of the main clinical characteristics and the indirect estimation of the complexity of the patients, a simple calculation of the average cost of the attention and its adverse events can be designed in patients who are admitted due to hip fracture. Additionally, this tool can fit the welfare quality indicators by severity and cost.

  14. High physical work load and low job satisfaction increase the risk of sickness absence due to low back pain: results of a prospective cohort study.

    Science.gov (United States)

    Hoogendoorn, W E; Bongers, P M; de Vet, H C W; Ariëns, G A M; van Mechelen, W; Bouter, L M

    2002-05-01

    To determine whether physical and psychosocial load at work influence sickness absence due to low back pain. The research was a part of the study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), a 3 year prospective cohort study on risk factors for musculoskeletal disorders. Workers from 21 companies located throughout The Netherlands participated in the part of this study on sickness absence due to low back pain. The study population consisted of 732 workers with no sickness absences of 3 days or longer due to low back pain in the 3 months before the baseline survey and complete data on the reasons for absences during the follow up period. The mean (range) period of follow up in this group was 37 (7-44) months. Physical load at work was assessed by analyses of video recordings. Baseline information on psychosocial work characteristics was obtained by a questionnaire. Data on sickness absence were collected from company records. The main outcome measure was the rate of sickness absences of 3 days or longer due to low back pain during the follow up period. After adjustment of the work related physical and psychosocial factors for each other and for other potential determinants, significant rate ratios ranging from 2.0 to 3.2 were found for trunk flexion, trunk rotation, lifting, and low job satisfaction. A dose-response relation was found for trunk flexion, but not for trunk rotation or lifting. Non-significant rate ratios of about 1.4 were found for low supervisor support and low coworker support. Quantitative job demands, conflicting demands, decision authority, and skill discretion showed no relation with sickness absence due to low back pain. Flexion and rotation of the trunk, lifting, and low job satisfaction are risk factors for sickness absence due to low back pain. Some indications of a relation between low social support, either from supervisors or coworkers, and sickness absence due to low back pain are also present.

  15. High physical work load and low job satisfaction increase the risk of sickness absence due to low back pain: Results of a prospective cohort study

    NARCIS (Netherlands)

    Hoogendoorn, W.E.; Bongers, P.M.; Vet, H.C.W. de; Ariëns, G.A.M.; Mechelen, W. van; Bouter, L.M.

    2002-01-01

    Objective: To determine whether physical and psychosocial load at work influence sickness absence due to low back pain. Methods: The research was a part of the study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), a 3 year prospective cohort study on risk factors for

  16. High physical work load and low job satisfaction increase the risk of sickness absence due to low back pain: results of a prospective cohort study

    NARCIS (Netherlands)

    Hoogendoorn, W.E.; Bongers, P.M.; de Vet, H.C.W.; Ariens, G.A.M.; van Mechelen, W.; Bouter, L.M.

    2002-01-01

    Objective: To determine whether physical and psychosocial load at work influence sickness absence due to low back pain. Methods: The research was a part of the study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), a 3 year prospective cohort study on risk factors for

  17. High physical work load and low job satisfaction increase the risk of sickness absence due to low back pain : results of a prospective cohort study

    NARCIS (Netherlands)

    Hoogendoorn, W E; Bongers, P M; de Vet, H C W; Ariëns, G A M; van Mechelen, W; Bouter, L M

    OBJECTIVE: To determine whether physical and psychosocial load at work influence sickness absence due to low back pain. METHODS: The research was a part of the study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), a 3 year prospective cohort study on risk factors for

  18. ANALYSIS OF RESULTS ON CROP LOSS CLOVES WOODEN VESSELS DUE TO ATTACK BACTERIA CLOVES (BPKC CASE STUDY IN SUB-DISTRICT WONOSALAM DISTRICT JOMBANG

    Directory of Open Access Journals (Sweden)

    Bambang Wicaksono Hariyadi

    2017-07-01

    serangan BPKC adalah sangat merugikan petani, terutama yang diserang tanaman–tanaman yang produktif. Disamping itu mereka perlu adanya bibit unggul yang tahan terhadap BPKC dan petani merasa putus asa karena tidak berhasil memberantas penyakit tersebut, meskipun sudah berusaha dan berupaya semaksimal mungkin. Kata Kunci  : Kehilangan Hasil, Tanaman Cengkeh, BPKC.  ABSTRACT: The purpose of this study is to a determine and tabulate the ownership of land area and the number of plants (trees planted clove farmers or planters; b to analyze how much the intensity of disease BPKC to damage plants (trees clove owned by farmers or planters; c to analyze how much yield loss and loss of production (in rupiah cloves BPKC due to disease; d describing the public perception of farmers or planters to disease (BPKC and the efforts to prevent and mitigate them.This research is a descriptive case study. The population in this study is the clove farmers in the District Wonosalam Jombang. The sample of the study population is determined by purposive side of a group of cloves farmers. Respondents consisted of eight (8 farmer groups and eight (8 members of farmer groups, so that a total of 16 people. Data collection, both primary data and secondary data by interview, observation and documentation.The results of this study indicate that the total tenure of 16 respondents covering 33.3 hectares with a total population of clove plant 4435 trees, which consists of 2,704 trees and 1,663 healthy trees attacked BPKC conditions. So the affected plants BPKC as much as 37.49% or intensity values Attacks (ISR amounted to 37.49%.Average land ownership per farmer area of 2.1 hectares with a population of 277.1 clove plant a tree, where the number of trees attacked by 108.1 healthy trees and 169 trees, then the value of Intensity Attack (ISR amounted to 39.01%.Losing Results Cloves of 22.5 quintal per year, or approximately 39.01% per year, thus reducing the income or the income of farmers or

  19. Work-focused cognitive behavioral intervention for psychological complaints in patients on sick leave due to work-related stress: Results from a randomized controlled trial.

    Science.gov (United States)

    Dalgaard, Vita Ligaya; Andersen, Lars Peter Sønderbo; Andersen, Johan Hviid; Willert, Morten Vejs; Carstensen, Ole; Glasscock, David John

    2017-08-22

    Work-related stress is a global problem with negative implications for individuals and society. The purpose of the current study was to evaluate a stress management intervention for patients on sick leave due to work-related stress complaints using a three-armed randomized controlled design. Participants were patients referred from three municipalities to the regional Department of Occupational Medicine. Inclusion criteria were: 1) sick leave due to work-related stress complaints, 2) a diagnosis of adjustment disorder or reactions to severe stress (ICD 10 code: F43,2 - F 43,9 not PTSD) or mild depressive episode (F 32.0). Through a double randomization procedure patients (n = 163) were randomized to either an intervention group (n = 58), a 'control group A' receiving a clinical examination (n = 56), or 'control group B' (n = 49) receiving no offers at the department. The intervention comprised six sessions of individual cognitive behavioral therapy and the offer of a small workplace intervention. Questionnaire data were analyzed with multivariate repeated measurements analysis. Primary outcomes assessed were perceived stress and general mental health. Secondary outcomes were sleep quality and cognitive failures. Follow-up was at four and 10 months after baseline. Complaints were significantly reduced in all groups over time. No group effects were observed between the intervention group and control group A that was clinically assessed. Significant group effects were found for perceived stress and memory when comparing the intervention group to group B, but most likely not due to an intervention effect. Psychological complaints improved substantially over time in all groups, but there was no significant treatment effect on any outcomes when the intervention group was compared to control group A that received a clinical assessment. ISRCTN ISRCTN91404229. Registered 03 August 2012 (retrospectively registered).

  20. A misleading false-negative result using Neisseria gonorrhoeae opa MGB multiplex PCR assay in patient's rectal sample due to partial mutations of the opa gene.

    Science.gov (United States)

    Vahidnia, Ali; van Empel, Pieter Jan; Costa, Sandra; Oud, Rob T N; van der Straaten, Tahar; Bliekendaal, Harry; Spaargaren, Joke

    2015-07-01

    A 53-year-old homosexual man presented at his general practitioner (GP) practice with a suspicion of sexually transmitted infection. Initial NAAT screening was performed for Chlamydia trachomatis and Neisseria gonorrhoeae. The patient was positive for Neisseria gonorrhoeae both for his urine and rectal sample. The subsequent confirmation test for Neisseria gonorrhoeae by a second laboratory was only confirmed for the urine sample and the rectal sample was negative. We report a case of a potential false-negative diagnosis of Neisseria gonorrhoeae due to mutations of DNA sequence in the probe region of opa-MGB assay of the rectal sample. The patient did not suffer any discomfort as diagnosis of Neisseria gonorrhoeae in his urine sample had already led to treatment by prescribing the patient with Ceftriaxone 500 mg IV dissolved in 1 ml lidocaine 2% and 4 mL saline. The patient also received a prescription for Azithromycin (2x500 mg).

  1. Results of the regional intercomparison on internal dosimetry – 2013: Interpretation of monitoring data for effective dose assessment due to internal exposure

    International Nuclear Information System (INIS)

    Rojo, A.M.; Puerta, N.; Gossio, S.; Gómez Parada, I.

    2015-01-01

    Internal dosimetry intercomparisons are essential for the verification of the models applied and the results consistency. To that aim, the 1. Regional Intercomparison Exercise was organized in 2005 in the frame of the RLA 9/049. The results of this exercise led to the 2. Regional Intercomparison Exercise in 2013, which was organized in the frame of the RLA 9/066 and coordinated by Autoridad Regulatoria Nuclear (ARN) of Argentina. Four simulated cases covering intakes of “1”3”1I, “1”3”7Cs and Tritium were proposed. The exercise counted with the participation of 19 centres from 13 countries. This report shows a complete analysis of the participant’s results in this 2nd. exercise, useful to test their skills and acquired knowledge, particularly in applying the IDEAS guidelines. It is important to highlight the improvement in the general performance of the participants. (authors) [es

  2. Results of the Argentinian intercomparison on internal dosimetry – 2014. Interpretation of monitoring data for effective dose assessment due to internal exposure

    International Nuclear Information System (INIS)

    Rojo, A.M.; Puerta, N.; Gossio, S.; Gómez Parada, I.

    2015-01-01

    Internal dosimetry intercomparisons are essential for the verification of the models applied and the results consistency. To that aim, in 2014 the National Intercomparison Exercise was organized and coordinated by the Internal Dosimetry Laboratory of the Nuclear Regulatory Authority (ARN) of Argentina. Four simulated cases covering intakes of “1”3”1I, “1”3”7Cs and tritium were proposed. The exercise counted with the participation of four internal dosimetry services from the nuclear power plants (NA-SA CNA and NA-SA CNE) and the CNEA Atomic Centres: Bariloche (CAB) and Ezeiza (CAE). This report shows a complete analysis of the participant’s results in this exercise. (authors) [es

  3. CO{sub 2} emissions resulting from the energy use; Les emissions de CO{sub 2} dues a l'utilisation de l'energie

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This document brings statistical data on the carbon dioxide emissions resulting from the energy use only. Tables and charts present data for the CO{sub 2} emissions in France, in the world (2001-2002), in the OECD (2000-2002), the CO{sub 2} emissions from electric power plants and refineries in France (1996-1999) and archives of statistics on CO{sub 2} emissions. (A.L.B.)

  4. Effects of carvedilol in heart failure due to dilated cardiomyopathy. Results of a double-blind randomized placebo-controlled study (CARIBE study

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Chizzola

    2000-03-01

    Full Text Available OBJECTIVE: To assess the effects of carvedilol in patients with idiopathic dilated cardiomyopathy. METHODS: In a double-blind randomized placebo-controlled study, 30 patients (7 women with functional class II and III heart failure were assessed. Their ages ranged from 28 to 66 years (mean of 43±9 years, and their left ventricular ejection fraction varied from 8% to 35%. Carvedilol was added to the usual therapy of 20 patients; placebo was added to the usual therapy of 10 patients. The initial dose of carvedilol was 12.5 mg, which was increased weekly until it reached 75 mg/day, according to the patient's tolerance. Clinical assessment, electrocardiogram, echocardiogram, and radionuclide ventriculography were performed in the pretreatment phase, being repeated after 2 and 6 months of medication use. RESULTS: A reduction in heart rate (p=0.016 as well as an increase in left ventricular shortening fraction (p=0.02 and in left ventricular ejection fraction (p=0.017 occurred in the group using carvedilol as compared with that using placebo. CONCLUSION: Carvedilol added to the usual therapy for heart failure resulted in better heart function.

  5. Discrepant serum and urine β-hCG results due to production of β-hCG by a cribriform-morular variant of thyroid papillary carcinoma.

    Science.gov (United States)

    Alikhan, Mir; Koshy, Anoopa; Hyjek, Elizabeth; Stenson, Kerstin; Cohen, Ronald N; Yeo, Kiang-Teck J

    2015-01-01

    Although patients with medullary thyroid cancer are known to present with paraneoplastic hormone production, this is much less common with papillary thyroid cancer. We present a patient with the cribriform morular variant of papillary thyroid cancer in association with familial adenomatous polyposis who developed a positive pregnancy test in the absence of known pregnancy. The patient had developed vaginal bleeding, and her laboratory testing was characterized by elevated serum human chorionic gonadotropin (β-hCG) concentrations, but negative qualitative urine results. After a thorough gynecological evaluation to exclude unexpected normal, ectopic, or molar pregnancy, we pursued an evaluation for other sources of β-hCG production. We showed that the elevated serum β-hCG concentrations were not the result of heterophile antibody interferences, and ultimately we proved that her recurrent tumor produced the ectopic β-hCG. This is the first report of β-hCG production by papillary thyroid cancer. Thus, the possibility of ectopic production of β-hCG by papillary thyroid cancer needs to be included in the differential diagnosis of elevated hCG concentration in the absence of pregnancy. This study of an unusual paraneoplastic syndrome highlights the importance of investigating discrepancies in the clinical laboratory. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Medical specialists' views on the impact of reducing alcohol consumption on prognosis of, and risk of, hospital admission due to specific medical conditions: results from a Delphi survey.

    Science.gov (United States)

    Mdege, Noreen D; Raistrick, Duncan; Johnson, Graham

    2014-02-01

    To find consensus, or lack thereof, on the impact of reducing alcohol consumption on prognosis and the risk of hospital admissions for a number of alcohol-attributable disorders. A modified two-round Delphi survey utilizing web-based questionnaires to collect quantitative and qualitative data was used. Alcohol treatment experts from cardiology, emergency medicine, gastroenterology and oncology in the United Kingdom were invited to participate. The main outcomes were median impact ratings (on a scale of 1-9) and consensus (unanimous, strong, moderate, weak or no consensus). Of 192 experts invited to participate, 59 completed first questionnaires. The overall retention rate to the second questionnaires was about 51% (30/59). There was strong support that reducing alcohol consumption could result in improvement in prognosis for gastroenterology and emergency medicine patients; but uncertainty on the benefits for cardiology and oncology patients. Overall, the responses from the expert panel did not reflect the assumption that reducing alcohol consumption would result in benefits on hospital admissions for any of the specialties. The specialists viewed the severity of disorders as important when considering the impact of reducing alcohol consumption. The highest impact of treatment for problem drinking in hospitals is considered to be for alcohol-related disorders associated with gastroenterology and emergency medicine. At policy level, if targeted screening for alcohol problems by presenting disease or condition is the strategy of choice, it would be logical to implement screening and easily accessible interventions or addiction specialists within these areas where alcohol treatment is considered as having a high impact. © 2013 John Wiley & Sons, Ltd.

  7. Evaluation of spurious results in the infrared measurement of CO2 isotope ratios due to spectral effects: a computer simulation study

    International Nuclear Information System (INIS)

    Mansfield, C.D.; Rutt, H.N.

    1999-01-01

    The application of infrared spectroscopy to the measurement of carbon isotope ratio breath tests is a promising alternative to conventional techniques, offering relative simplicity and lower costs. However, when designing such an instrument one should be conscious of several spectral effects that may be misinterpreted as changes in the isotope concentration and which therefore lead to spurious results. Through a series of computer simulations which model the behaviour of the CO 2 absorption spectrum, the risk these effects pose to reliable measurement of 13 CO 2 / 12 CO 2 ratios and the measures required to eliminate them are evaluated. The computer model provides a flexible high-resolution spectrum of the four main isotopomer fundamental transitions and fifteen of their most significant hotband transitions. It is demonstrated that the infrared source, infrared windows and breath sample itself all exhibit strong temperature-induced errors but pressure effects do not produce significant errors. We conclude that for reliable measurement of 13 CO 2 / 12 CO 2 ratios using infrared spectroscopy no pressure controls are required, window effects are eliminated using windows wedged at a minimum angle of 0.8-2.2 mrad, depending on the material, and the temperature sensitivity of source and gas cells necessitates stabilization to an accuracy of at least 0.2 K. (author)

  8. Overexpression of rice black-streaked dwarf virus p7-1 in Arabidopsis results in male sterility due to non-dehiscent anthers.

    Directory of Open Access Journals (Sweden)

    Feng Sun

    Full Text Available Rice black-streaked dwarf virus (RBSDV, a member of the genus Fijivirus in the family Reoviridae, is propagatively transmitted by the small brown planthopper (Laodelphax striatellus Fallén. RBSDV causes rice black-streaked dwarf and maize rough dwarf diseases, which lead to severe yield losses in crops in China. Although several RBSDV proteins have been studied in detail, the functions of the nonstructural protein P7-1 are still largely unknown. To investigate the role of the P7-1 protein in virus pathogenicity, transgenic Arabidopsis thaliana plants were generated in which the P7-1 gene was expressed under the control of the 35S promoter. The RBSDV P7-1-transgenic Arabidopsis plants (named P7-1-OE were male sterility. Flowers and pollen from P7-1-transgenic plants were of normal size and shape, and anthers developed to the normal size but failed to dehisce. The non-dehiscent anthers observed in P7-1-OE were attributed to decreased lignin content in the anthers. Furthermore, the reactive oxygen species levels were quite low in the transgenic plants compared with the wild type. These results indicate that ectopic expression of the RBSDV P7-1 protein in A. thaliana causes male sterility, possibly through the disruption of the lignin biosynthesis and H2O2-dependent polymerization pathways.

  9. Overexpression of rice black-streaked dwarf virus p7-1 in Arabidopsis results in male sterility due to non-dehiscent anthers.

    Science.gov (United States)

    Sun, Feng; Yuan, Xia; Xu, Qiufang; Zhou, Tong; Fan, Yongjian; Zhou, Yijun

    2013-01-01

    Rice black-streaked dwarf virus (RBSDV), a member of the genus Fijivirus in the family Reoviridae, is propagatively transmitted by the small brown planthopper (Laodelphax striatellus Fallén). RBSDV causes rice black-streaked dwarf and maize rough dwarf diseases, which lead to severe yield losses in crops in China. Although several RBSDV proteins have been studied in detail, the functions of the nonstructural protein P7-1 are still largely unknown. To investigate the role of the P7-1 protein in virus pathogenicity, transgenic Arabidopsis thaliana plants were generated in which the P7-1 gene was expressed under the control of the 35S promoter. The RBSDV P7-1-transgenic Arabidopsis plants (named P7-1-OE) were male sterility. Flowers and pollen from P7-1-transgenic plants were of normal size and shape, and anthers developed to the normal size but failed to dehisce. The non-dehiscent anthers observed in P7-1-OE were attributed to decreased lignin content in the anthers. Furthermore, the reactive oxygen species levels were quite low in the transgenic plants compared with the wild type. These results indicate that ectopic expression of the RBSDV P7-1 protein in A. thaliana causes male sterility, possibly through the disruption of the lignin biosynthesis and H2O2-dependent polymerization pathways.

  10. Defective Proteolytic Processing of Fibrillar Procollagens and Prodecorin Due to Biallelic BMP1 Mutations Results in a Severe, Progressive Form of Osteogenesis Imperfecta.

    Science.gov (United States)

    Syx, Delfien; Guillemyn, Brecht; Symoens, Sofie; Sousa, Ana Berta; Medeira, Ana; Whiteford, Margo; Hermanns-Lê, Trinh; Coucke, Paul J; De Paepe, Anne; Malfait, Fransiska

    2015-08-01

    Whereas the vast majority of osteogenesis imperfecta (OI) is caused by autosomal dominant defects in the genes encoding type I procollagen, mutations in a myriad of genes affecting type I procollagen biosynthesis or bone formation and homeostasis have now been associated with rare autosomal recessive OI forms. Recently, homozygous or compound heterozygous mutations in BMP1, encoding the metalloproteases bone morphogenetic protein-1 (BMP1) and its longer isoform mammalian Tolloid (mTLD), were identified in 5 children with a severe autosomal recessive form of OI and in 4 individuals with mild to moderate bone fragility. BMP1/mTLD functions as the procollagen carboxy-(C)-proteinase for types I to III procollagen but was also suggested to participate in amino-(N)-propeptide cleavage of types V and XI procollagens and in proteolytic trimming of other extracellular matrix (ECM) substrates. We report the phenotypic characteristics and natural history of 4 adults with severe, progressive OI characterized by numerous fractures, short stature with rhizomelic shortening, and deformity of the limbs and variable kyphoscoliosis, in whom we identified novel biallelic missense and frameshift mutations in BMP1. We show that BMP1/mTLD-deficiency in humans not only results in delayed cleavage of the type I procollagen C-propeptide but also hampers the processing of the small leucine-rich proteoglycan prodecorin, a regulator of collagen fibrillogenesis. Immunofluorescent staining of types I and V collagen and transmission electron microscopy of the dermis show impaired assembly of heterotypic type I/V collagen fibrils in the ECM. Our study thus highlights the severe and progressive nature of BMP1-associated OI in adults and broadens insights into the functional consequences of BMP1/mTLD-deficiency on ECM organization. © 2015 American Society for Bone and Mineral Research.

  11. Predictions of turbidity due to enhanced sediment resuspension resulting from sea-level rise on a fringing Coral Reef: Evidence from Molokai, Hawaii

    Science.gov (United States)

    Ogston, A.S.; Field, M.E.

    2010-01-01

    Accelerating sea-level rise associated with global climate change will affect sedimentary processes on coral reefs and other shoreline environments by increasing energy and sediment resuspension. On reefs, sedimentation is known to increase coral stress and bleaching as particles that settle on coral surfaces interfere with photosynthesis and feeding, and turbidity induced by suspended sediment reduces incident light levels. Using relationships developed from observations of wave orbital velocity, water-surface elevation, and suspended-sediment concentration on a fringing reef flat of Molokai, Hawaii, predictions of the average daily maximum in suspended-sediment concentration increase from ~11 mg/l to ~20 mg/l with 20 cm sea-level rise. The duration of time concentrations exceeds 10 mg/l increases from 9 to 37. An evaluation of the reduction of wave energy flux through breaking and frictional dissipation across the reef flat shows an increase of ~80 relative to the present will potentially reach the shoreline as sea level increases by 20 cm. Where the shoreline exists on low, flat terrain, the increased energy could cause significant erosion of the shoreline. Considering the sediment budget, the sediment flux is predicted to increase and removal of fine-grained sediment may be expedited on some fringing reefs, and sediment in storage on the inner reef could ultimately be reduced. However, increased shoreline erosion may add sediment and offset removal from the reef flat. The shifts in sediment availability and transport that will occur as result of a modest increase in sea level have wide application to fringing coral reefs elsewhere, as well as other shoreline environments. ?? 2010 the Coastal Education & Research Foundation (CERF).

  12. Corruption of accuracy and efficiency of Markov chain Monte Carlo simulation by inaccurate numerical implementation of conceptual hydrologic models

    Science.gov (United States)

    Schoups, G.; Vrugt, J. A.; Fenicia, F.; van de Giesen, N. C.

    2010-10-01

    Conceptual rainfall-runoff models have traditionally been applied without paying much attention to numerical errors induced by temporal integration of water balance dynamics. Reliance on first-order, explicit, fixed-step integration methods leads to computationally cheap simulation models that are easy to implement. Computational speed is especially desirable for estimating parameter and predictive uncertainty using Markov chain Monte Carlo (MCMC) methods. Confirming earlier work of Kavetski et al. (2003), we show here that the computational speed of first-order, explicit, fixed-step integration methods comes at a cost: for a case study with a spatially lumped conceptual rainfall-runoff model, it introduces artificial bimodality in the marginal posterior parameter distributions, which is not present in numerically accurate implementations of the same model. The resulting effects on MCMC simulation include (1) inconsistent estimates of posterior parameter and predictive distributions, (2) poor performance and slow convergence of the MCMC algorithm, and (3) unreliable convergence diagnosis using the Gelman-Rubin statistic. We studied several alternative numerical implementations to remedy these problems, including various adaptive-step finite difference schemes and an operator splitting method. Our results show that adaptive-step, second-order methods, based on either explicit finite differencing or operator splitting with analytical integration, provide the best alternative for accurate and efficient MCMC simulation. Fixed-step or adaptive-step implicit methods may also be used for increased accuracy, but they cannot match the efficiency of adaptive-step explicit finite differencing or operator splitting. Of the latter two, explicit finite differencing is more generally applicable and is preferred if the individual hydrologic flux laws cannot be integrated analytically, as the splitting method then loses its advantage.

  13. Accurate, inaccurate, or biased teacher expectations: Do Dutch teachers differ in their expectations at the end of primary education?

    Science.gov (United States)

    Timmermans, Anneke C; Kuyper, Hans; van der Werf, Greetje

    2015-12-01

    In several tracked educational systems, realizing optimal placements in classes in the first year of secondary education depends on the accuracy of teacher expectations. The aim of this study was to investigate between-teacher differences in their expectations regarding the academic aptitude of their students. The sample consisted of 500 teachers (classes) who provided their expectations of 7,550 students in the final grade of Dutch primary education. We analysed the extent to which teachers differed in their expectations and in what contexts their expectations were biased, using multilevel random slope models. Multilevel analysis showed teacher expectation bias to be related to gender and socio-ethnic background of students. The differences among teachers in expectations for Turkish, Moroccan, and other foreign students with low-educated parents were larger than the average teacher expectation bias for these groups in the sample. When student characteristics were controlled for, we found that the teachers in our sample had higher expectations for students in high-performing classes or classes with only a small proportion of students from low-SES families. Teacher expectation bias for demographic groups, however, was found to be independent of the class population. The results indicate the importance of the teacher and the necessity of using multilevel models when investigating the complex nature of between-teacher differences in expectations of student performance. © 2015 The British Psychological Society.

  14. [Inaccurate information about the size of the penis in the Democratic Republic of the Congo: about 21 information sources].

    Science.gov (United States)

    Mulenga, Philippe Cilundika; Kazadi, Alex Bukasa

    2016-01-01

    Penis size is a huge topic of anxiety for a lot of men. Some of them are unhappy with their penis size as shown in the study conducted by Tiggemann in 2008. There are relatively few studies on erect penis size. This may reflect cultural taboos of researchers or doctors interacting with men who are in a state of sexual arousal. On the other hand, it is important for people who announce details on penis size to give the average penis size first and then sizes suggested by the researchers. We performed a cross-sectional survey in the two major urban centres of the Democratic Republic of Congo namely Kinshasa and Lubumbashi over a period of two years from May 2014 to May 2016. A total of 21 information sources constituted our sample, 8 in Kinshasa and 13 in Lubumbashi. We found it sufficient because in our culture discussing about sexual matter is rare. The parameters studied were: the nature of the source, the accuracy of the measurement method, the presence of bibliographical reference, the announced penis size. The majority of information sources used were radio or television broadcastings (23,8%); this can be explained by the fact that there are an increasing number of radio and television stations in our country and especially in large cities. With regard to accuracy of information about penis measurement method when sharing the message about penis size, our study showed that the majority of information sources did not indicate it when they announced penis size to the public (85,7%). Several sources did not report bibliographical references (57,1%). Announced data analysis on penis size showed that the average penis size was: 14 cm (28,6%), 15 cm (23,8%) and 15-20 cm (19%). All these results are intended to offer a warning to all players responsible for diffusing information on sexual health (penis size): scientific rigor consists in seeking information from reliable sources.

  15. Forecasts: uncertain, inaccurate and biased?

    DEFF Research Database (Denmark)

    Nicolaisen, Morten Skou; Ambrasaite, Inga; Salling, Kim Bang

    2012-01-01

    Cost Benefit Analysis (CBA) is the dominating methodology for appraisal of transport infrastructure projects across the globe. In order to adequately assess the costs and benefits of such projects two types of forecasts are crucial to the validity of the appraisal. First are the forecasts of cons....... It is recommended that more attention is given to monitoring completed projects so future forecasts can benefit from better data availability through systematic ex-post evaluations, and an example of how to utilize such data in practice is presented....

  16. Differential time to positivity of central and peripheral blood cultures is inaccurate for the diagnosis of Staphylococcus aureus long-term catheter-related sepsis.

    Science.gov (United States)

    Bouzidi, H; Emirian, A; Marty, A; Chachaty, E; Laplanche, A; Gachot, B; Blot, F

    2018-02-10

    Differential time to positivity of cultures of blood drawn simultaneously from central venous catheter and peripheral sites is widely used to diagnose catheter-related bloodstream infections without removing the catheter. However, the accuracy of this technique for some pathogens, such as Staphylococcus aureus, is debated in routine practice. In a 320-bed reference cancer centre, the charts of patients with at least one blood culture positive for S. aureus among paired blood cultures drawn over a six-year period were studied retrospectively. Microbiological data were extracted from the prospectively compiled database of the microbiology unit. Data concerning the 149 patients included were reviewed retrospectively by independent physicians blinded to the absolute and differential times to positivity, in order to establish or refute the diagnosis of catheter-related sepsis. Due to missing data, 48 charts were excluded, so 101 cases were actually analysed. The diagnosis was established in 62 cases, refuted in 15 cases and inconclusive in the remaining 24 cases. For the 64 patients with both central and peripheral positive blood cultures, the differential positivity time was significantly greater for patients with catheter-related bloodstream infections due to S. aureus (Pcatheter-related bloodstream infection due to S. aureus. These results strongly suggest that despite its high specificity, the differential time to positivity may not be reliable to rule out catheter-related bloodstream infection due to S. aureus. Copyright © 2018. Published by Elsevier Ltd.

  17. Bootstrap imputation with a disease probability model minimized bias from misclassification due to administrative database codes.

    Science.gov (United States)

    van Walraven, Carl

    2017-04-01

    Diagnostic codes used in administrative databases cause bias due to misclassification of patient disease status. It is unclear which methods minimize this bias. Serum creatinine measures were used to determine severe renal failure status in 50,074 hospitalized patients. The true prevalence of severe renal failure and its association with covariates were measured. These were compared to results for which renal failure status was determined using surrogate measures including the following: (1) diagnostic codes; (2) categorization of probability estimates of renal failure determined from a previously validated model; or (3) bootstrap methods imputation of disease status using model-derived probability estimates. Bias in estimates of severe renal failure prevalence and its association with covariates were minimal when bootstrap methods were used to impute renal failure status from model-based probability estimates. In contrast, biases were extensive when renal failure status was determined using codes or methods in which model-based condition probability was categorized. Bias due to misclassification from inaccurate diagnostic codes can be minimized using bootstrap methods to impute condition status using multivariable model-derived probability estimates. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Transurethral Resection of the Prostate (TURP) Versus Original and PErFecTED Prostate Artery Embolization (PAE) Due to Benign Prostatic Hyperplasia (BPH): Preliminary Results of a Single Center, Prospective, Urodynamic-Controlled Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Carnevale, Francisco C., E-mail: fcarnevale@uol.com.br [University of Sao Paulo Medical School, Interventional Radiology Unit (Brazil); Iscaife, Alexandre, E-mail: iscaifeboni@yahoo.com.br; Yoshinaga, Eduardo M., E-mail: dumuracca@ig.com.br [University of Sao Paulo Medical School, Division of Urology (Brazil); Moreira, Airton Mota, E-mail: motamoreira@gmail.com [University of Sao Paulo Medical School, Interventional Radiology Unit (Brazil); Antunes, Alberto A., E-mail: antunesuro@uol.com.br; Srougi, Miguel, E-mail: srougi@uol.com.br [University of Sao Paulo Medical School, Division of Urology (Brazil)

    2016-01-15

    PurposeTo compare clinical and urodynamic results of transurethral resection of the prostate (TURP) to original and PErFecTED prostate artery embolization (PAE) methods for benign prostatic hyperplasia.MethodsWe prospectively randomized 30 patients to receive TURP or original PAE (oPAE) and compared them to a cohort of patients treated by PErFecTED PAE, with a minimum of 1-year follow-up. Patients were assessed for urodynamic parameters, prostate volume, international prostate symptom score (IPSS), and quality of life (QoL).ResultsAll groups were comparable for all pre-treatment parameters except bladder contractility and peak urine flow rate (Q{sub max}), both of which were significantly better in the TURP group, and IIEF score, which was significantly higher among PErFecTED PAE patients than TURP patients. All groups experienced significant improvement in IPSS, QoL, prostate volume, and Q{sub max}. TURP and PErFecTED PAE both resulted in significantly lower IPSS than oPAE but were not significantly different from one another. TURP resulted in significantly higher Q{sub max} and significantly smaller prostate volume than either original or PErFecTED PAE but required spinal anesthesia and hospitalization. Two patients in the oPAE group with hypocontractile bladders experienced recurrence of symptoms and were treated with TURP. In the TURP group, urinary incontinence occurred in 4/15 patients (26.7 %), rupture of the prostatic capsule in 1/15 (6.7 %), retrograde ejaculation in all patients (100 %), and one patient was readmitted for temporary bladder irrigation due to hematuria.ConclusionsTURP and PAE are both safe and effective treatments. TURP and PErFecTED PAE yield similar symptom improvement, but TURP is associated with both better urodynamic results and more adverse events.

  19. Transurethral Resection of the Prostate (TURP) Versus Original and PErFecTED Prostate Artery Embolization (PAE) Due to Benign Prostatic Hyperplasia (BPH): Preliminary Results of a Single Center, Prospective, Urodynamic-Controlled Analysis.

    Science.gov (United States)

    Carnevale, Francisco C; Iscaife, Alexandre; Yoshinaga, Eduardo M; Moreira, Airton Mota; Antunes, Alberto A; Srougi, Miguel

    2016-01-01

    To compare clinical and urodynamic results of transurethral resection of the prostate (TURP) to original and PErFecTED prostate artery embolization (PAE) methods for benign prostatic hyperplasia. We prospectively randomized 30 patients to receive TURP or original PAE (oPAE) and compared them to a cohort of patients treated by PErFecTED PAE, with a minimum of 1-year follow-up. Patients were assessed for urodynamic parameters, prostate volume, international prostate symptom score (IPSS), and quality of life (QoL). All groups were comparable for all pre-treatment parameters except bladder contractility and peak urine flow rate (Q max), both of which were significantly better in the TURP group, and IIEF score, which was significantly higher among PErFecTED PAE patients than TURP patients. All groups experienced significant improvement in IPSS, QoL, prostate volume, and Q max. TURP and PErFecTED PAE both resulted in significantly lower IPSS than oPAE but were not significantly different from one another. TURP resulted in significantly higher Q max and significantly smaller prostate volume than either original or PErFecTED PAE but required spinal anesthesia and hospitalization. Two patients in the oPAE group with hypocontractile bladders experienced recurrence of symptoms and were treated with TURP. In the TURP group, urinary incontinence occurred in 4/15 patients (26.7 %), rupture of the prostatic capsule in 1/15 (6.7 %), retrograde ejaculation in all patients (100 %), and one patient was readmitted for temporary bladder irrigation due to hematuria. TURP and PAE are both safe and effective treatments. TURP and PErFecTED PAE yield similar symptom improvement, but TURP is associated with both better urodynamic results and more adverse events.

  20. [Anaphylaxis due to peach with negative ImmunoCAP result to peach allergens, including rPru p 1, rPru p 3, AND rPru p 4: a report of two cases].

    Science.gov (United States)

    Maeda, Nobuko; Inomata, Naoko; Morita, Akiko; Kirino, Mio; Moriyama, Tatsuya; Ikezawa, Zenro

    2009-02-01

    We report two cases of anaphylactic reactions to peach with negative result of ImmunoCAP to peach. Case 1 is a 35-year-old man, who felt an itch in his oral cavity immediately after ingesting a whole fresh peach. He rapidly developed generalized urticaria, dyspnea, vomiting, and loss of consciousness. He recovered after treatment at a local hospital, thereafter he was referred to our hospital because ImmunoCAP conducted for screening allergens revealed a negative test result to peach and the cause of anaphylaxis remained unclear. He had a history of pollinosis. He reported that he previously felt an itch on his oral cavity after ingesting melon, watermelon, apple, and strawberry. Serum total IgE was 436 IU/ml. CAP-RAST revealed negative results to peach, strawberry and kiwi. Skin prick tests (SPTs) with raw peach pulp, canned peach pulp, strawberry and kiwi were positive. Case 2 is a 30-year-old woman who felt an itch on her oral cavity accompanied by blepharedema, rhinorrhea, generalized urticaria, nausea, abdominal pain and diarrhea after eating peach. She had a history of pollinosis. She reported that she previously developed urticaria after ingesting an apple. Serum total IgE was 85 IU/ml. ImmunoCAP revealed negative results to peach and apple. SPTs with canned yellow peach, strawberry and apple were positive. Consequently, the two patients were diagnosed with anaphylaxis due to peach, and allergic symptoms have never recurred since they avoided ingesting peach. Furthermore, in two patients ImmunoCAP to rPru p 1, rPru p 3, and rPru p 4 were negative. However, in IgE-immunoblotting of peach, serum IgE antibodies of two patients were bound to approximately 10 kDa proteins. Meanwhile, the cross-reactivity between Rosaceae fruits, such as peach, apple, apricot, and plum, has been reported. These results suggest that in patients, who are suspected of having peach anaphylaxis and show a negative ImmunoCAP result to peach, the additional testing, such as SPT with

  1. Long-term results of high-dose conformal radiotherapy for patients with medically inoperable T1-3N0 non-small-cell lung cancer: Is low incidence of regional failure due to incidental nodal irradiation?

    International Nuclear Information System (INIS)

    Chen Ming; Hayman, James A.; Haken, Randall K. ten; Tatro, Daniel; Fernando, Shaneli; Kong, F.-M.

    2006-01-01

    Purpose: To report the results of high-dose conformal irradiation and examine incidental nodal irradiation and nodal failure in patients with inoperable early-stage non-small-cell lung cancer (NSCLC). Methods and Materials: This analysis included patients with inoperable CT-staged T1-3N0M0 NSCLC treated on our prospective dose-escalation trial. Patients were treated with radiation alone (total dose, 63-102.9 Gy in 2.1-Gy daily fractions) with a three-dimensional conformal technique without intentional nodal irradiation. Bilateral highest mediastinal and upper/lower paratracheal, prevascular and retrotracheal, sub- and para-aortic, subcarinal, paraesophageal, and ipsilateral hilar regions were delineated individually. Nodal failure and doses of incidental irradiation were studied. Results: The potential median follow-up was 104 months. For patients who completed protocol treatment, median survival was 31 months. The actuarial overall survival rate was 86%, 61%, 43%, and 21% and the cause-specific survival rate was 89%, 70%, 53%, and 35% at 1, 2, 3, and 5 years, respectively. Weight loss (p = 0.008) and radiation dose in Gy (p = 0.013) were significantly associated with overall survival. In only 22% and 13% of patients examined did ipsilateral hilar and paratracheal (and subaortic for left-sided tumor) nodal regions receive a dose of ≥40 Gy, respectively. Less than 10% of all other nodal regions received a dose of ≥40 Gy. No patients failed initially at nodal sites. Conclusions: Radiation dose is positively associated with overall survival in patients with medically inoperable T1-3N0 NSCLC, though long-term results remain poor. The nodal failure rate is low and does not seem to be due to high-dose incidental irradiation

  2. Daidzein plus isolase associated with zinc improves clinical symptoms and quality of life in patients with LUTS due to benign prostatic hyperplasia: Results from a phase I-II study

    Directory of Open Access Journals (Sweden)

    Daniele Tiscione

    2017-03-01

    Full Text Available Objective: In the last years there is a growing interest in nutraceutical substances that seems able to improve clinical symptoms in patients with lower urinary tract symptoms (LUTS due to benign prostatic hyperplasia (BPH. In this paper, we evaluated both efficacy and safety of a combination of daidzein with isolase and zinc in patients with LUTS due to BPH. Materials and methods: In a phase I-II study clinical trial we enrolled patients with clinical and instrumental diagnosis of LUTS associated to BPH that received a six-month treatment with a combination of daidzein with isolase and zinc (1 tablet/day. Clinical, laboratory and instrumental analyses were carried out at the time of admission (T0 and 6 months after the ending of the treatment (T1. The Italian version of International Prostatic Symptom Score (IPSS, International Index of Erectile Function (IIEF-5 and Quality of Well-Being (QoL questionnaires were used. The development of adverse drug reactions (ADRs and drug interactions (DDIs were recorded using the Naranjo scale and drug interaction probability scale. Student’s t test and Anova test were used for statistical analysis, and the threshold of statistical significance was set at P < 0.05. Results: We enrolled 71 patients, 62 (87.3% completed the follow-up and we documented a significant differences between T0 and T1 in terms of IPSS [21.5 ± 1.2 vs 16.2 ± 1.5; (-4.8; p < 0.001], Cmax [9.7 ± 3.7 vs 15.3 ± 2.5; (+5.6; p < 0.001] and QoL [0.56 ± 0.15 vs 0.84 ± 0.19; (+0.28; p < 0.001]. In contrast, no significant difference were recorded in terms of IIEF-5 [p = 0.50] and PSA [p = 0.67]. Finally, we did not record any significant ADRs or DDIs during the study. Conclusions: In this study, we documented that a combination of daidzein with isolase and zinc, reduces the clinical symptoms of LUTS and improves the quality of life in patients with BPH, without the development of ADRs or DDIs.

  3. Higher clinical success in patients with ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus treated with linezolid compared with vancomycin: results from the IMPACT-HAP study

    OpenAIRE

    Peyrani, Paula; Wiemken, Timothy L; Kelley, Robert; Zervos, Marcus J; Kett, Daniel H; File Jr, Thomas M; Stein, Gary E; Ford, Kimbal D; Scerpella, Ernesto G; Welch, Verna; Ramirez, Julio A

    2014-01-01

    Introduction Controversy exists regarding optimal treatment for ventilator-associated pneumonia (VAP) due to methicillin-resistant Staphylococcus aureus (MRSA). The primary objective of this study was to compare clinical success of linezolid versus vancomycin for the treatment of patients with MRSA VAP. Methods This was a multicenter, retrospective, observational study of patients with VAP (defined according to Centers for Disease Control and Prevention criteria) due to MRSA who were treated ...

  4. Efficacy and safety of pasireotide-LAR for the treatment of refractory bleeding due to gastrointestinal angiodysplasias: results of the ANGIOPAS multicenter phase II noncomparative prospective double-blinded randomized study

    Science.gov (United States)

    Benamouzig, Robert; Benallaoua, Mourad; Saurin, Jean-Christophe; Boubaya, Marouane; Cellier, Christophe; Laugier, René; Vincent, Magalie; Boustière, Christian; Gincul, Rodica; Samaha, Elia; Grandval, Philippe; Aparicio, Thomas; Airinei, Gheorghe; Bejou, Bakhtiar; Bon, Cyriaque; Raynaud, Jean-Jacques; Levy, Vincent; Sautereau, Denis

    2018-01-01

    Background: Gastrointestinal angiodysplasias (GIADs) could be responsible for recurrent bleeding and severe anemia. Somatostatin analogs could reduce transfusion requirements in these patients but no randomized controlled study is available. The main objective of the ANGIOPAS phase II double-blinded randomized, noncomparative study was to assess the effectiveness of pasireotide-LAR in reducing transfusion requirements in patients with refractory GIADs bleeding. Methods: A total of 22 patients with transfusion requirements ⩾6 units of packed red blood cells (pRBCs) during the 6 months prior to inclusion were randomized to receive pasireotide-LAR 60 mg (n = 10) or placebo (n = 12) every 28 days for 6 months. Patients were then followed for an additional 6 months after stopping treatment. Results: The pasireotide-LAR and placebo groups were equivalent for age, sex, comorbidities and transfusion requirement during the reference period (median 13 and 9.5 pRBCs). A 50 and 83% success rate (success defined as a decrease of at least 30% of transfused pRBCs) was observed in the pasireotide-LAR arm in the Intent to Treat (ITT) and per protocol (PP) analysis respectively. The need for transfusion during the intervention period was 3 pRBC units in the pasireotide-LAR group (range 0–26) and 11.5 pRBC units in the placebo group (range 0–23). Overall, three cases with glycemic control impairment were observed in the pasireotide-LAR group including one de novo diabetes. Conclusion: This double-blinded noncomparative randomized phase II study suggests, for the first time, the effectiveness of pasireotide-LAR 60 mg every 28 days to decrease the transfusion requirement in patients with recurrent bleeding due to GIADs. PMID:29479375

  5. Evaluation of stress intensity factors due to welding residual stresses for circumferential cracked pipes

    International Nuclear Information System (INIS)

    Oh, Chang-Young; Kim, Yun-Jae; Oh, Young-Jin; Kim, Jong-Sung; Song, Tae-Kwang; Kim, Yong-Beum

    2013-01-01

    To investigate the applicability of existing methods to estimate stress intensity factors due to welding residual stresses, comparisons with finite element (FE) solutions are made for two types of generic welding residual stress profiles, generated by simulating repair welds. It is found that fitting residual stresses over the crack depth using third-order polynomials gives good estimates of stress intensity factors but fitting over the entire thickness can result in inaccurate estimates even with fourth-order polynomials. Noting that welding residual stresses are often determined from FE analyses, linearization of residual stresses to estimate stress intensity factors is proposed. Comparison with FE solutions shows good agreements. -- Highlights: ► Applicability of K estimation methods is investigated for welding residual stresses. ► Two types of generic residual stress profiles with repair welds are considered. ► Fitting residual stresses over the crack depth gives good estimates of K. ► A method to estimate K by linearising residual stress profiles is proposed

  6. Comparison of dual mobility cup and other surgical construts used for three hundred and sixty two first time hip revisions due to recurrent dislocations: five year results from Lithuanian arthroplasty register.

    Science.gov (United States)

    Stucinskas, Justinas; Kalvaitis, Tomas; Smailys, Alfredas; Robertsson, Otto; Tarasevicius, Sarunas

    2018-05-01

    Recently, there has been increasing interest in the use of dual mobility systems in the treatment of hip instability. The aim of this study was to investigate the re-revision rate of dual mobility cup compared to different surgical concepts when used for first-time hip revisions due to recurrent dislocations. The data were derived from the Lithuanian Arthroplasty Register. For survival analysis, we used both re-revision for all reasons and for dislocations as an end-point. Cox proportional hazards models were used to analyze the influence of various covariates (age, gender, and implant concept). A total of 1388 revisions were recorded from 2011 to 2015, of which 362 were performed due to recurrent dislocation. Of the revisions, 247 were performed using dual mobility cups, while 115 were performed using a variety of other surgical constructs including constrained acetabular cups, conventional cups, femoral head exchanges, stem exchanges or anti-luxation rings. There were 27 re-revisions of which 15 were for additional dislocations. There were only 2% re-revisions due to dislocation with dual mobility vs 9% when using other surgical constructs. Cox regression adjusting for age and gender showed that in the short-term, dual mobility cup had a lower risk of revision due to dislocation as well as for all reasons compared to the other surgical constructs. In revision of total hip arthroplasties for dislocation, significantly lower short-term re-revision rate was observed for patients revised with dual mobility cup.

  7. Diplopia due to Dacryops

    Directory of Open Access Journals (Sweden)

    Rahmi Duman

    2013-01-01

    Full Text Available Dacryops is a lacrimal ductal cyst. It is known that it can cause globe displacement, motility restriction, and proptosis because of the mass effect. Diplopia due to dacryops has not been reported previously. Here, we present a 57-year-old man with binocular horizontal diplopia that occurred during left direction gaze due to dacryops.

  8. Higher clinical success in patients with ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus treated with linezolid compared with vancomycin: results from the IMPACT-HAP study.

    Science.gov (United States)

    Peyrani, Paula; Wiemken, Timothy L; Kelley, Robert; Zervos, Marcus J; Kett, Daniel H; File, Thomas M; Stein, Gary E; Ford, Kimbal D; Scerpella, Ernesto G; Welch, Verna; Ramirez, Julio A

    2014-06-10

    Controversy exists regarding optimal treatment for ventilator-associated pneumonia (VAP) due to methicillin-resistant Staphylococcus aureus (MRSA). The primary objective of this study was to compare clinical success of linezolid versus vancomycin for the treatment of patients with MRSA VAP. This was a multicenter, retrospective, observational study of patients with VAP (defined according to Centers for Disease Control and Prevention criteria) due to MRSA who were treated with linezolid or vancomycin. MRSA VAP was considered when MRSA was isolated from a tracheal aspirate or bronchoalveolar lavage. Clinical success was evaluated by assessing improvement or resolution of signs and symptoms of VAP by day 14. After matching on confounding factors, logistic regression models were used to determine if an association existed between treatment arm and clinical success. A total of 188 patients were evaluated (101 treated with linezolid and 87 with vancomycin). The mean ± standard deviation Acute Physiology and Chronic Health Evaluation (APACHE) II score was 21 ± 11 for linezolid- and 19 ± 9 for vancomycin-treated patients (P = 0.041). Clinical success occurred in 85% of linezolid-treated patients compared with 69% of vancomycin-treated patients (P = 0.009). After adjusting for confounding factors, linezolid-treated patients were 24% more likely to experience clinical success than vancomycin-treated patients (P = 0.018). This study adds to the evidence indicating that patients with MRSA VAP who are treated with linezolid are more likely to respond favorably compared with patients treated with vancomycin.

  9. Due process traditionalism.

    Science.gov (United States)

    Sunstein, Cass R

    2008-06-01

    In important cases, the Supreme Court has limited the scope of "substantive due process" by reference to tradition, but it has yet to explain why it has done so. Due process traditionalism might be defended in several distinctive ways. The most ambitious defense draws on a set of ideas associated with Edmund Burke and Friedrich Hayek, who suggested that traditions have special credentials by virtue of their acceptance by many minds. But this defense runs into three problems. Those who have participated in a tradition may not have accepted any relevant proposition; they might suffer from a systematic bias; and they might have joined a cascade. An alternative defense sees due process traditionalism as a second-best substitute for two preferable alternatives: a purely procedural approach to the Due Process Clause, and an approach that gives legislatures the benefit of every reasonable doubt. But it is not clear that in these domains, the first-best approaches are especially attractive; and even if they are, the second-best may be an unacceptably crude substitute. The most plausible defense of due process traditionalism operates on rule-consequentialist grounds, with the suggestion that even if traditions are not great, they are often good, and judges do best if they defer to traditions rather than attempting to specify the content of "liberty" on their own. But the rule-consequentialist defense depends on controversial and probably false assumptions about the likely goodness of traditions and the institutional incapacities of judges.

  10. Is questionnaire-based sitting time inaccurate and can it be improved? A cross-sectional investigation using accelerometer-based sitting time

    DEFF Research Database (Denmark)

    Gupta, Nidhi; Christiansen, Caroline Stordal; Hanisch, Christiana

    2017-01-01

    Objectives To investigate the differences between a questionnaire-based and accelerometer-based sitting time, and develop a model for improving the accuracy of questionnaire-based sitting time for predicting accelerometer-based sitting time. Methods 183 workers in a cross-sectional study reported...... sitting time per day using a single question during the measurement period, and wore 2 Actigraph GT3X+ accelerometers on the thigh and trunk for 1-4 working days to determine their actual sitting time per day using the validated Acti4 software. Least squares regression models were fitted...... with questionnaire-based siting time and other self-reported predictors to predict accelerometer-based sitting time. Results Questionnaire-based and accelerometer-based average sitting times were ≈272 and ≈476min/day, respectively. A low Pearson correlation (r=0.32), high mean bias (204.1min) and wide limits...

  11. Independent risk factors for the development of skin erosion due to incontinence (incontinence-associated dermatitis category 2) in nursing home residents: results from a multivariate binary regression analysis.

    Science.gov (United States)

    Van Damme, Nele; Van den Bussche, Karen; De Meyer, Dorien; Van Hecke, Ann; Verhaeghe, Sofie; Beeckman, Dimitri

    2017-10-01

    The aim of this study was to identify characteristics independently associated with a higher risk of developing skin damage because of incontinence [incontinence-associated dermatitis (IAD) category 2] in nursing home residents. As part of a larger randomised controlled trial, IAD incidence was monitored for 1 month in a sample of 381 incontinent residents using a validated IAD Severity Categorisation Tool. Data on demographical, physical, functional and psychological characteristics were collected. The overall IAD incidence (category 1-2) was 30·0%, and 6% of the participants developed skin damage (IAD category 2). Residents who developed IAD category 2 were less mobile [odds ratio (OR) 2·72, 95% confidence interval (CI) 1·06-6·94], had more friction and shear issues (OR 2·54; 95% CI 1·02-6·33) and had more erythema due to incontinence (OR 3·02; 95% CI 1·04-8·73) before IAD category 2 occurrence. Care providers should give full attention to risk factors to both detect residents at risk for IAD development and to start prevention in time. © 2016 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

  12. Is questionnaire-based sitting time inaccurate and can it be improved? A cross-sectional investigation using accelerometer-based sitting time

    Science.gov (United States)

    Gupta, Nidhi; Christiansen, Caroline Stordal; Hanisch, Christiana; Bay, Hans; Burr, Hermann; Holtermann, Andreas

    2017-01-01

    Objectives To investigate the differences between a questionnaire-based and accelerometer-based sitting time, and develop a model for improving the accuracy of questionnaire-based sitting time for predicting accelerometer-based sitting time. Methods 183 workers in a cross-sectional study reported sitting time per day using a single question during the measurement period, and wore 2 Actigraph GT3X+ accelerometers on the thigh and trunk for 1–4 working days to determine their actual sitting time per day using the validated Acti4 software. Least squares regression models were fitted with questionnaire-based siting time and other self-reported predictors to predict accelerometer-based sitting time. Results Questionnaire-based and accelerometer-based average sitting times were ≈272 and ≈476 min/day, respectively. A low Pearson correlation (r=0.32), high mean bias (204.1 min) and wide limits of agreement (549.8 to −139.7 min) between questionnaire-based and accelerometer-based sitting time were found. The prediction model based on questionnaire-based sitting explained 10% of the variance in accelerometer-based sitting time. Inclusion of 9 self-reported predictors in the model increased the explained variance to 41%, with 10% optimism using a resampling bootstrap validation. Based on a split validation analysis, the developed prediction model on ≈75% of the workers (n=132) reduced the mean and the SD of the difference between questionnaire-based and accelerometer-based sitting time by 64% and 42%, respectively, in the remaining 25% of the workers. Conclusions This study indicates that questionnaire-based sitting time has low validity and that a prediction model can be one solution to materially improve the precision of questionnaire-based sitting time. PMID:28093433

  13. Human due diligence.

    Science.gov (United States)

    Harding, David; Rouse, Ted

    2007-04-01

    Most companies do a thorough job of financial due diligence when they acquire other companies. But all too often, deal makers simply ignore or underestimate the significance of people issues in mergers and acquisitions. The consequences are severe. Most obviously, there's a high degree of talent loss after a deal's announcement. To make matters worse, differences in decision-making styles lead to infighting; integration stalls; and productivity declines. The good news is that human due diligence can help companies avoid these problems. Done early enough, it helps acquirers decide whether to embrace or kill a deal and determine the price they are willing to pay. It also lays the groundwork for smooth integration. When acquirers have done their homework, they can uncover capability gaps, points of friction, and differences in decision making. Even more important, they can make the critical "people" decisions-who stays, who goes, who runs the combined business, what to do with the rank and file-at the time the deal is announced or shortly thereafter. Making such decisions within the first 30 days is critical to the success of a deal. Hostile situations clearly make things more difficult, but companies can and must still do a certain amount of human due diligence to reduce the inevitable fallout from the acquisition process and smooth the integration. This article details the steps involved in conducting human due diligence. The approach is structured around answering five basic questions: Who is the cultural acquirer? What kind of organization do you want? Will the two cultures mesh? Who are the people you most want to retain? And how will rank-and-file employees react to the deal? Unless an acquiring company has answered these questions to its satisfaction, the acquisition it is making will be very likely to end badly.

  14. Results of the Marine Ice Sheet Model Intercomparison Project, MISMIP

    Directory of Open Access Journals (Sweden)

    F. Pattyn

    2012-05-01

    Full Text Available Predictions of marine ice-sheet behaviour require models that are able to robustly simulate grounding line migration. We present results of an intercomparison exercise for marine ice-sheet models. Verification is effected by comparison with approximate analytical solutions for flux across the grounding line using simplified geometrical configurations (no lateral variations, no effects of lateral buttressing. Unique steady state grounding line positions exist for ice sheets on a downward sloping bed, while hysteresis occurs across an overdeepened bed, and stable steady state grounding line positions only occur on the downward-sloping sections. Models based on the shallow ice approximation, which does not resolve extensional stresses, do not reproduce the approximate analytical results unless appropriate parameterizations for ice flux are imposed at the grounding line. For extensional-stress resolving "shelfy stream" models, differences between model results were mainly due to the choice of spatial discretization. Moving grid methods were found to be the most accurate at capturing grounding line evolution, since they track the grounding line explicitly. Adaptive mesh refinement can further improve accuracy, including fixed grid models that generally perform poorly at coarse resolution. Fixed grid models, with nested grid representations of the grounding line, are able to generate accurate steady state positions, but can be inaccurate over transients. Only one full-Stokes model was included in the intercomparison, and consequently the accuracy of shelfy stream models as approximations of full-Stokes models remains to be determined in detail, especially during transients.

  15. Erratum regarding inaccurate authorship attributions noted.

    Science.gov (United States)

    2017-01-01

    For the paper entitled Pain improvement in rheumatoid arthritis with hyperbaric oxygen: report of three cases,' which appeared in the July-August 2016 issue of UHM (43-4), author attributions read as: John B. Slade MD, Mary V. Potts RN, Alan M. Flower DO, Michelle T. Sit MD, Thomas W. Schmidt MD. Undersea Hyperb Med. 2016 Jul-Aug; 43(4): 467-472. The corrected authorship reads as: John B. Slade MD, Mary V. Potts RN, Alan M. Flower DO, Karen M. Sky, MD, FACP, FACR, Michelle T. Sit MD, Thomas W. Schmidt MD. Undersea Hyperb Med. 2016 Jul-Aug; 43(4): 467-472. Dr. Karen M. Sky was inadvertently deleted from the list of authors. UHM apologizes for the omission.

  16. Gathering asychronous mobile robots with inaccurate compasses

    OpenAIRE

    Souissi, Samia; Defago, Xavier; Yamashita, Masafumi

    2006-01-01

    This paper considers a system of asynchronous autonomous mobile robots that can move freely in a twodimensional plane with no agreement on a common coordinate system. Starting from any initial configuration, the robots are required to eventually gather at a single point, not fixed in advance (gathering problem). Prior work has shown that gathering oblivious (i.e., stateless) robots cannot be achieved deterministically without additional assumptions. In particular, if robots can detect multipl...

  17. New localities of Orobanche bartlingii Griseb. in the Silesian-Cracow Upland as a result of the spread of Libanotis pyrenaica (L. Bourg. due to the changes in land use

    Directory of Open Access Journals (Sweden)

    Babczyńska-Sendek Beata

    2015-09-01

    Full Text Available Human activity is a factor strongly influencing the current state of vegetation. The abandonment of traditional land use enables uncontrolled secondary succession. Libanotis pyrenaica, a host plant for Orobanche bartlingii, is a great example of species that spread as a result of this process, especially in the area of the Silesian-Cracow Upland. The aim of this study is to show that the expansion of L. pyrenaica caused by changes in land use promotes spreading of O. bartlingii - a species rare in Poland and Europe. During the field research conducted in the last decade, further localities of O. bartlingii were found. The gathered data were summarized to supplement the known distribution of the species and to present floristic and ecological characteristics of the phytocenoses with the participation of L. pyrenaica and O. bartlingii.

  18. Review of evaluations of crushing results for the seedbed preparation

    Directory of Open Access Journals (Sweden)

    Siegfried Anisch

    2016-06-01

    Full Text Available For evaluating the work results of tillage operations today only inaccurate parameters are available which cannot be readily measured. Thus, evaluating and comparing the work results of machines and developing suitable sensors are difficult. At the Technical University of Dresden, till 1990, research projects for determining aggregate size composition of soil have been done. Based on this work, this study will show suggestions for measuring, displaying and evaluation of soil crushing results depending on tillage work conditions.

  19. Evaluation of uncertainty in dam-break analysis resulting from dynamic representation of a reservoir; Evaluation de l'incertitude due au modele de representation du reservoir dans les analyses de rupture de barrage

    Energy Technology Data Exchange (ETDEWEB)

    Tchamen, G.W.; Gaucher, J. [Hydro-Quebec Production, Montreal, PQ (Canada). Direction Barrage et Environnement, Unite Barrages et Hydraulique

    2010-08-15

    Owners and operators of high capacity dams in Quebec have a legal obligation to conduct dam break analysis for each of their dams in order to ensure public safety. This paper described traditional hydraulic methodologies and models used to perform dam break analyses. In particular, it examined the influence of the reservoir drawdown submodel on the numerical results of a dam break analysis. Numerical techniques from the field of fluid mechanics and aerodynamics have provided the basis for developing effective hydrodynamic codes that reduce the level of uncertainties associated with dam-break analysis. A static representation that considers the storage curve was compared with a dynamic representation based on Saint-Venant equations and the real bathymetry of the reservoir. The comparison was based on breach of reservoir, maximum water level, flooded area, and wave arrival time in the valley downstream. The study showed that the greatest difference in attained water level was in the vicinity of the dam, and the difference decreased as the distance from the reservoir increased. The analysis showed that the static representation overestimated the maximum depth and inundated area by as much as 20 percent. This overestimation can be reduced by 30 to 40 percent by using dynamic representation. A dynamic model based on a synthetic trapezoidal reconstruction of the storage curve was used, given the lack of bathymetric data for the reservoir. It was concluded that this model can significantly reduce the uncertainty associated with the static model. 7 refs., 9 tabs., 7 figs.

  20. [Keratitis due to Acanthamoeba].

    Science.gov (United States)

    Pérez-Irezábal, Julio; Martínez, Inés; Isasa, Patricia; Barrón, Jorge

    2006-10-01

    Free-living amebae appertaining to the genus Acanthamoeba, Naegleria and Balamuthia are the most prevalent protozoa found in the environment. These amebae have a cosmopolitan distribution in soil, air and water, providing multiple opportunities for contacts with humans and animals, although they only occasionally cause disease. Acanthamoeba spp. are the causative agent of granulomatous amebic encephalitis, a rare and often fatal disease of the central nervous system, and amebic keratitis, a painful disease of the eyes. Keratitis usually follows a chronic course due to the delay in diagnosis and subsequent treatment. The clear increase in Acanthamoeba keratitis in the last 20 years is related to the use and deficient maintenance of contact lenses, and to swimming while wearing them. The expected incidence is one case per 30,000 contact lens wearers per year, with 88% of cases occurring in persons wearing hydrogel lenses. This review presents information on the morphology, life-cycle and epidemiology of Acanthamoeba, as well as on diagnostic procedures (culture), appropriate antimicrobial therapy, and prevention measures.

  1. Credit where credit's due?

    Science.gov (United States)

    Hargittai, Magdolna

    2012-09-01

    It is often said that physicist Chien-Shiung Wu, who was born 100 years ago, should have received a share in the 1957 Nobel Prize for Physics but missed out as a result of gender discrimination. Magdolna Hargittai investigates the truth of the matter.

  2. Scleritis Due to Histoplasmosis.

    Science.gov (United States)

    Dalvin, Lauren A; Thom, Steven B; García, Joaquín J; Fadel, Hind J; Baratz, Keith H

    2016-03-01

    To describe the first-documented case of histoplasma scleritis in an immunocompetent patient. Medical and pathological records of the patient described were reviewed. A 77-year-old immunocompetent man presented with necrotizing scleritis. Biopsy was consistent with histoplasma species, and culture results confirmed a causative agent of Histoplasma capsulatum. The patient required a long course of treatment, which included topical voriconazole and amphotericin, oral itraconazole and voriconazole, intravenous amphotericin, and periocular voriconazole and amphotericin. After 8 months of treatment, the patient's scleritis resolved, and he maintained good visual acuity. To our knowledge, this is the second report of histoplasma scleritis in the literature and the first report in an immunocompetent patient.

  3. due to Capillary Forces

    Directory of Open Access Journals (Sweden)

    Hassen M. Ouakad

    2009-01-01

    Full Text Available We present modeling and analysis for the static behavior and collapse instabilities of doubly-clamped and cantilever microbeams subjected to capillary forces. These forces can be as a result of a volume of liquid trapped underneath the microbeam during the rinsing and drying process in fabrication. The model considers the microbeam as a continuous medium, the capillary force as a nonlinear function of displacement, and accounts for the mid-plane stretching and geometric nonlinearities. The capillary force is assumed to be distributed over a specific length underneath the microbeam. The Galerkin procedure is used to derive a reduced-order model consisting of a set of nonlinear algebraic and differential equations that describe the microbeams static and dynamic behaviors. We study the collapse instability, which brings the microbeam from its unstuck configuration to touch the substrate and gets stuck in the so-called pinned configuration. We calculate the pull-in length that distinguishes the free from the pinned configurations as a function of the beam thickness and gap width for both microbeams. Comparisons are made with analytical results reported in the literature based on the Ritz method for linear and nonlinear beam models. The instability problem, which brings the microbeam from a pinned to adhered configuration is also investigated. For this case, we use a shooting technique to solve the boundary-value problem governing the deflection of the microbeams. The critical microbeam length for this second instability is also calculated.

  4. Onycomycosis due to artificial nails.

    Science.gov (United States)

    Shemer, A; Trau, H; Davidovici, B; Grunwald, M H; Amichai, B

    2008-08-01

    The use of artificial nails (ANs) as part of nail-care cosmetics is very popular. Several side effects and complications, such as contact dermatitis and bacterial and fungal infections, have been reported in patients using ANs. Objective The purpose of this study was to identify the fungal pathogens in nail abnormalities appearing in patients with ANs. We evaluated 68 patients suffering from nail changes and paronychia, which appear after removal of ANs. Mycological samples were obtained from two sites: distal parts of the involved nail and the proximal nail fold. KOH examination and fungal culture were used for detection and identification of fungal infection. Mycological results from the distal part of the nail showed positive KOH test in 57 cases (83.8%), and culture was positive in 67 patients (98.5%). Mycological results obtained from the proximal nail fold showed positive KOH test in 36 patients (52.9%); in 36 of the cases, culture was positive. Candida spp. were the most common pathogen. Both KOH and culture results were significantly better while sampling from the distal part of the nail compared with sampling from the proximal nail fold (P = 0.0001). Onychomycosis was found to be very common in nail changes due to ANs, leading to an increased risk of transmitting microbial infections. Therefore, health care personnel and workers in the food industry should avoid using ANs.

  5. Hazards to Effective Due Diligence

    Directory of Open Access Journals (Sweden)

    Michael Benoliel

    2015-03-01

    Full Text Available It is not surprising that many business deals fail to realize their expected future value because some deal makers fail to perform effective due diligence. Successful deal makers, however, know that due diligence is one of the most important tasks in successful deal making. Thus, they avoid the psychological and contextual traps that cause poor due diligence. In this article, I describe the hazards – the psychological biases and contextual factors – that might affect the due diligence task. These hazards include information availability bias; confirmation bias; overconfidence bias; time pressure; self-interested agents; deal fever; narrow focus; and complexity. Following this review, I provide a number of suggestions to help deal makers and organizations overcome these hazards.

  6. Confidence crisis of results in biomechanics research.

    Science.gov (United States)

    Knudson, Duane

    2017-11-01

    Many biomechanics studies have small sample sizes and incorrect statistical analyses, so reporting of inaccurate inferences and inflated magnitude of effects are common in the field. This review examines these issues in biomechanics research and summarises potential solutions from research in other fields to increase the confidence in the experimental effects reported in biomechanics. Authors, reviewers and editors of biomechanics research reports are encouraged to improve sample sizes and the resulting statistical power, improve reporting transparency, improve the rigour of statistical analyses used, and increase the acceptance of replication studies to improve the validity of inferences from data in biomechanics research. The application of sports biomechanics research results would also improve if a larger percentage of unbiased effects and their uncertainty were reported in the literature.

  7. Hazard report. Incorrect measurement of uterine cavity while using Hologic NovaSure endometrial ablation system can result in patient injury.

    Science.gov (United States)

    2009-09-01

    If the uterine cavity is improperly or inaccurately measured during use of the Hologic NovaSure endometrial ablation system, it could result in thermal or perforation injuries. This article describes some of these injuries and offers guidance on reducing their likelihood.

  8. Avaliação dos resultados da artroplastia parcial de ombro para tratamento da artropatia por lesão do manguito rotador Evaluating the results of partial shoulder arthroplasty for the treatment of arthropathy due to rotator cuff lesion

    Directory of Open Access Journals (Sweden)

    Sérgio Luiz Checchia

    2008-06-01

    Full Text Available OBJETIVO: Avaliar os resultados obtidos com a artroplastia parcial de ombro para o tratamento da artropatia por lesão do manguito rotador. MÉTODOS: No período de junho de 1989 a março de 2004, 11 ombros de 11 pacientes foram submetidos a artroplastia parcial de ombro para o tratamento de artropatia por LMR. O tempo de seguimento variou de 27 a 183 meses, com média de 69 meses. A idade média foi de 69,1 anos, variando de 44 a 78 anos. Houve predomínio do sexo feminino em 90,9% dos casos (10 pacientes. O membro dominante foi acometido em 10 pacientes. Os métodos escolhidos para avaliação dos pacientes, no seguimento pós-operatório, basearam-se nos critérios da UCLA; no índice de satisfação dos pacientes em relação ao alívio da dor; e no método de avaliação de objetivos limitados, proposto por Neer et al. RESULTADOS: O índice de satisfação dos pacientes em relação ao alívio da dor foi de 81,8%. Com o método de avaliação da UCLA, observamos média de 22,7 pontos. Por meio do método de avaliação de objetivos limitados, proposto por Neer et al, obtivemos seis pacientes com resultados satisfatórios e cinco insatisfatórios. CONCLUSÃO: A artroplastia parcial de ombro para o tratamento da artropatia por lesão do manguito rotador promove alívio do quadro doloroso e permite alguma melhora na função do membro para realização das atividades diárias; entretanto, é uma técnica que leva a altos índices de resultados insatisfatórios.OBJECTIVE: To evaluate the results achieved with partial arthroplasty of the shoulder to treat arthropathy due to rotator cuff lesion. METHODS: From June 1989 to March 2004, 11 shoulders of 11 patients were submitted to partial arthroplasty of the shoulder to treat an arthropathy due to rotator cuff lesion. Follow-up time varied from 27 to 182 months, with a mean of 69 months. Mean age was 69.1 years, ranging from 44 to 78 years. There was a predominance of the female gender, in 90.9% of

  9. Autoerotic death due to electrocution

    Directory of Open Access Journals (Sweden)

    Piotr Arkuszewski

    2014-08-01

    Full Text Available Autoerotic death is a very rare case in forensic medicine. It is usually caused by asphyxia, but other reasons are also possible. Herein we present a case of autoerotic death due to electrocution caused by a self-made electrical device. The device was constructed to increase sexual feelings through stimulation of the scrotal area.

  10. [Immediate type allergies due to metal - nickel].

    Science.gov (United States)

    van Kampen, V; Merget, R; Brüning, T

    2003-11-01

    Occupational allergies of the immediate type due to metals, which are predominantly caused by nickel, platinum, chromium and cobalt, are rather rare. The present paper reviews the results of the evaluation of literature data concerning the occupational airway sensitization due to nickel, which is used in many different industrial fields - especially in the electroplating industry. Cases of specific airway sensizitation caused by nickel are verified by a number of studies, predominantly case histories. In conclusion, there is sufficient evidence that nickel may cause IgE-mediated hypersensitivity with typical symptoms.

  11. Maculopathy due to drug inhalation.

    Science.gov (United States)

    Asensio-Sánchez, V M; Gonzalez-Buendia, L; Marcos-Fernández, M

    2014-08-01

    A case of maculopathy due to "poppers" is described. Poppers is a drug composed of various forms of alkyl nitrite. A 39 year-old man, who had been using poppers for years, was seen in the clinic with phosphenes, reduced visual acuity and central scotoma. The SD-OCT in the right eye showed disruption at the level of the IS/OS junction line. The SD-OCT scan in the left eye showed an outer rectangular retinal hole and an outer retinal cyst. Copyright © 2012 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

  12. [Infections due to Mycobacterium simiae].

    Science.gov (United States)

    García-Martos, Pedro; García-Agudo, Lidia; González-Moya, Enrique; Galán, Fátima; Rodríguez-Iglesias, Manuel

    2015-10-01

    Mycobacterium simiae is a slow-growing photochromogenic environmental mycobacterium, first described in 1965. Rarely associated with human infections, possibly due to its limited pathogenicity, it mainly produces lung infection in immunocompetent elderly patients with underlying lung disease, and in disseminated infections in immunosuppressed young patients with AIDS. A microbiological culture is needed to confirm the clinical suspicion, and genetic sequencing techniques are essential to correctly identify the species. Treating M. simiae infections is complicated, owing to the multiple resistance to tuberculous drugs and the lack of correlation between in vitro susceptibility data and in vivo response. Proper treatment is yet to be defined, but must include clarithromycin combined with other antimicrobials such as moxifloxacin and cotrimoxazole. It is possible that M. simiae infections are undiagnosed. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  13. Occupational injuries due to violence.

    Science.gov (United States)

    Hales, T; Seligman, P J; Newman, S C; Timbrook, C L

    1988-06-01

    Each year in the United States, an estimated 800 to 1,400 people are murdered at work, and an unknown number of nonfatal injuries due to workplace violence occur. Based on Ohio's workers' compensation claims from 1983 through 1985, police officers, gasoline service station employees, employees of the real estate industry, and hotel/motel employees were found to be at the highest risk for occupational violent crime (OVC) injury and death. Grocery store employees, specifically those working in convenience food stores, and employees of the real estate industry had the most reported rapes. Four previously unidentified industries at increased risk of employee victimization were described. Identification of industries and occupations at high risk for crime victimization provides the opportunity to focus preventive strategies to promote employee safety and security in the workplace.

  14. Single fatherhood due to cancer.

    Science.gov (United States)

    Yopp, Justin M; Rosenstein, Donald L

    2012-12-01

    Cancer is a leading cause of widowed fatherhood in the USA. Fathers whose spouses have died from cancer constitute a potentially vulnerable population as they adjust to their role as sole or primary caregiver while managing their own grief and that of their children. The importance of addressing the psychological needs of widowed fathers is underscored by data showing that father's coping and emotional availability are closely tied to their bereaved children's mental health. Surprisingly, scant attention has been given to the phenomenon of widowed fatherhood with virtually no clinical resources or research studies devoted to fathers who have lost their wives to cancer. This commentary highlights key challenges facing this underserved population of widowers and calls for development of research agendas and clinical interventions for single fathers due to cancer. Copyright © 2011 John Wiley & Sons, Ltd.

  15. APPENDICULAR INVAGINATION DUE TO ENDOMETRIOSIS

    Directory of Open Access Journals (Sweden)

    Vasja Kruh

    2003-12-01

    Full Text Available Background. Invagination of the vermiform appendix is a very rare occurrence. We summarize epidemiologic and etiologic factors, types of classification, symtomatology, diagnostic features and treatment.Patients and treatment. The authors present 49-years old female with long-standing abdominal pains, who came in our hospital due to acute exacerbation with sever abdominal pain. Because of progressive symptoms and sensitivity in the right-lower abdominal quadrant a diagnostic laparoscopy was performed. An anomaly of cecum and the absence of appendix vermiformis have forced us to proceed with laparotomy in McBurnay point. After cecotomy an invaginated gangrenous appendix was found. The histological examination revealed endometriosis.Conclusions. By presenting this extremely rare pathology we also want to emphasize the important role of diagnostic laparoscopy in front of acute abdomen.

  16. Systemic contact dermatitis due to nickel

    Directory of Open Access Journals (Sweden)

    Taruli Olivia

    2015-08-01

    Full Text Available Introduction: Systemic contact dermatitis (SCD is a systemic reactivation of a previous allergic contact dermatitis. The initial exposure may usually be topical, followed by oral, intravenous or inhalation exposure leading to a systemic hypersensitivity reaction. A case of a 27 year-old male with SCD due to nickel is reported Case Report: A 27 year-old male presented with recurrent pruritic eruption consist of deep seated vesicles on both palmar and left plantar since 6 months before admission. This complaint began after patient consumed excessive amounts of chocolate, canned food, and beans. The patient worked as a technician in a food factory. History of allergy due to nickel was acknowledged since childhood. The clinical presentation was diffuse deep seated vesicles, and multiple erythematous macules to plaques, with collarette scale. Patch test using the European standard showed a +3 result to nickel. The patient was diagnosed as systemic contact dermatitis due to nickel. The treatments were topical corticosteroid and patient education of avoidance of both contact and systemic exposure to nickel. The patient showed clinical improvement after 2 weeks. Discussion: SCD was diagnosed due to the history of massive consumption of food containing nickel in a patient who had initial sensitization to nickel, with clinical features and the patch test result. Advice to be aware of nickel and its avoidance is important in SCD management.

  17. [Nephropathy due to Puumala hantavirus].

    Science.gov (United States)

    Dandolo, A; Prajs, N; Lizop, M

    2014-12-01

    Hemorrhagic fever with renal syndrome (HFRS) is due to an infection by the virus of the Hantavirus genus. Rodent hosts of Hantavirus are present in restricted areas in France; consequently, there are ecological niches and microepidemics of human Hantavirus infections. A HFRS case was diagnosed in the Paris region. The 11-year-old child had an acute debut fever-persistent despite antipyretic medication-asthenia, headache, abdominal pain, myalgia, thrombocytopenia, as well as renal failure with proteinuria. The diagnosis was made with a relevant clinical history and the specific serology of Puumala hantavirus. Therefore, a kidney biopsy was not necessary. What was interesting was the diagnostic approach because of the difference between the place and time of contamination and where the child became ill and developed the symptoms. The child was infected by Puumala hantavirus in Les Ardennes, a high-risk area, but became ill in the Paris region, an area with no prevalence. We review Hantavirus infections in France and its differential diagnosis. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  18. Stuttering Due To Ischemic Stroke

    OpenAIRE

    Sahin, Huseyin Alparslan; Krespi, Yakup; Yilmaz, Ahmet; Coban, Oguzhan

    2005-01-01

    Acquired stuttering is a disorder of the fluency of speech. The mechanism underlying stuttering is unknown. It may occur after bilateral and unilateral cortical or subcortical brain damage. We report two cases who had stuttering resulting from left parietal infarction.

  19. Neonatal cholestasis due to primary sclerosing cholangitis

    Directory of Open Access Journals (Sweden)

    Naman Sadanand Shetty

    2016-01-01

    Full Text Available Neonatal cholestasis is rarely caused due to primary sclerosing cholangitis, which is an inflammatory disease of the bile ducts, which results in obstructive fibrosis of the ducts. A 7-month-old male child presented with jaundice along with high-colored urine and clay-colored stools since birth. Liver biopsy showed mild bile duct proliferation with cholangioles showing bile and thrombi suggestive of primary sclerosing cholangitis.

  20. Perturbation theory for BAO reconstructed fields: One-loop results in the real-space matter density field

    Science.gov (United States)

    Hikage, Chiaki; Koyama, Kazuya; Heavens, Alan

    2017-08-01

    We compute the power spectrum at one-loop order in standard perturbation theory for the matter density field to which a standard Lagrangian baryonic acoustic oscillation (BAO) reconstruction technique is applied. The BAO reconstruction method corrects the bulk motion associated with the gravitational evolution using the inverse Zel'dovich approximation (ZA) for the smoothed density field. We find that the overall amplitude of one-loop contributions in the matter power spectrum substantially decreases after reconstruction. The reconstructed power spectrum thereby approaches the initial linear spectrum when the smoothed density field is close enough to linear, i.e., the smoothing scale Rs≳10 h-1 Mpc . On smaller Rs, however, the deviation from the linear spectrum becomes significant on large scales (k ≲Rs-1 ) due to the nonlinearity in the smoothed density field, and the reconstruction is inaccurate. Compared with N-body simulations, we show that the reconstructed power spectrum at one-loop order agrees with simulations better than the unreconstructed power spectrum. We also calculate the tree-level bispectrum in standard perturbation theory to investigate non-Gaussianity in the reconstructed matter density field. We show that the amplitude of the bispectrum significantly decreases for small k after reconstruction and that the tree-level bispectrum agrees well with N-body results in the weakly nonlinear regime.

  1. Resultados iniciais do transplante de células de medula óssea para o miocárdio de pacientes com insuficiência cardíaca de etiologia chagásica Early results of bone marrow cell transplantation to the myocardium of patients with heart failure due to chagas disease

    Directory of Open Access Journals (Sweden)

    Fábio Vilas-Boas

    2006-08-01

    Full Text Available OBJETIVO: Avaliar efeitos precoces do transplante de células de medula óssea para o miocárdio de pacientes com insuficiência cardíaca (IC de etiologia chagásica. MÉTODOS: A amostra consistiu de 28 pacientes, idade média 52,2±9,9 anos, 24 masculinos, 25 em classe NYHA III e 3 em NYHA IV, apesar de tratamento otimizado. O procedimento consistiu na aspiração de 50ml de medula óssea, separação da fração mononuclear e injeção intracoronariana. Foram avaliados os efeitos sobre a fração de ejeção ventricular esquerda (FEVE, distância no teste de 6 minutos, qualidade de vida, classe NYHA, efeitos arritmogênicos e bioquímicos. RESULTADOS: Não houve complicações relacionadas diretamente ao procedimento. A fração de ejeção ventricular esquerda em repouso antes do transplante era 20,1±6,8% e, após 60 dias, aumentou para 23,0±9,0%, p = 0,02. Houve melhora da classe NYHA (3,1±0,3 para 1,8±0,5; pOBJECTIVE: To evaluate early effects of bone marrow cell transplantation to the myocardium of patients with heart failure (CHF due to Chagas disease. METHODS: We studied 28 patients (mean age 52.2 ± 9.9, of whom 24 were male. Despite optimized treatment, 25 patients were in NYHA class III and three patients, in NYHA class IV. The procedure consisted of aspiration of 50 mL of bone marrow, separation of the mononuclear fraction, and intracoronary injection. Effects on left ventricle ejection fraction (LVEF, distance walked in the six-minute walking test, quality-of-life, NYHA class, arrhythmogenic and biochemical parameters, were all evaluated. RESULTS: There were no complications directly related to the procedure. Baseline left ventricular ejection fraction was 20.1 ± 6.8%, and 60 days after transplantation it increased to 23.0 ± 9.0%, p = 0.02. Significant improvements were observed in the NYHA class (3.1 ± 0.3 to 1.8 ± 0.5; p < 0.0001; quality-of-life (50.9 ± 11.7 to 21.8 ± 13.4; p < 0.0001; and distance walked in six

  2. Aplastic anemia due to radiation

    International Nuclear Information System (INIS)

    Sakai, Kunio; Saito, Akira

    1978-01-01

    The relationship between radiation exposure and aplastic anemia, clarified previously, is discussed. When persons such as radiological technicians receive whole-body irradiation in rather large doses, it is possible that aplastic anemia will result later on. However, this is difficult to determine because the irradiated region is limited despite large doses of radiation. (Bell, E.)

  3. Stuttering Due To Ischemic Stroke

    Directory of Open Access Journals (Sweden)

    Huseyin Alparslan Sahin

    2005-01-01

    Full Text Available Acquired stuttering is a disorder of the fluency of speech. The mechanism underlying stuttering is unknown. It may occur after bilateral and unilateral cortical or subcortical brain damage. We report two cases who had stuttering resulting from left parietal infarction.

  4. [Fatal poisoning due to Indigofera].

    Science.gov (United States)

    Labib, S; Berdai, M-A; Bendadi, A; Achour, S; Harandou, M

    2012-01-01

    Indigo, also known in Morocco as Nila, is a dye widely used in the coloring of Moroccan handicrafts. It is obtained from fermentation reactions on the leaves and branches of true indigo, Indigofera tinctoria, which is a widespread plant in tropical Africa and Asia. We report a case of fatal poisoning in a 3-year-old child after administration of indigo for therapeutic purposes. Death resulted from multiple organ failure. The toxicity of this compound is little known in the literature and deserves to be explored through toxicokinetic and toxicodynamic studies, in order to better determine the toxic constituents of the dye. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  5. GHG emissions due to deforestation

    International Nuclear Information System (INIS)

    Croezen, H.; Van Valkengoed, M.

    2009-05-01

    An assessment was made for the magnitude of greenhouse gas emissions resulting from deforestation and forest degradation in tropical forests in Malaysia and Indonesia related to Dutch economic activities. Greenhouse gas emissions (GHG) are calculated in relation to (1) the emissions related to vegetation removal sec; and (2) the emissions related to removal and more long term effects related to assimilation of CO2 in forest regrowth and changes in organic material in soils. Emissions related to vegetation removal and aggregated emissions for both vegetation removal and long term effects are reported separately. Soil organic carbon stock changes are considered by Greenpeace as more uncertain, so the emphasis will be on the direct emissions. Changes in carbon stocks and N2O emissions and actually also changes in vegetation all are events that occur gradually, rather than immediately. Only removal of existing vegetation and possible burning of this vegetation and associated emissions related to both activities are immediate by nature. Carbon stocks and N2O emissions change to a new level within several decades after deforestation or forest degradation. Removed vegetation can grow back or be replaced eventually by other vegetation, thereby changing the net greenhouse gas (GHG) emissions related to deforestation or forest degradation. Vegetation extracted for commercial purposes such as timber or pulp will also take years or decades to become waste and be converted into CO2. In IPCC and LCA's all these emissions are taken into account - or at least all emissions occurring within a period of 20 years, as required by IPCC. Soil organic carbon stock changes are also considered by Greenpeace as more uncertain, so the emphasis will be on the direct emmissions.

  6. Contamination Effects Due to Space Environmental Interactions

    Science.gov (United States)

    Chen, Philip T.; Paquin, Krista C. (Technical Monitor)

    2001-01-01

    Molecular and particulate contaminants are commonly generated from the orbital spacecraft operations that are under the influence of the space environment. Once generated, these contaminants may attach to the surfaces of the spacecraft or may remain in the vicinity of the spacecraft. In the event these contaminants come to rest on the surfaces of the spacecraft or situated in the line-of-sight of the observation path, they will create various degrees of contamination effect which may cause undesirable effects for normal spacecraft operations, There will be circumstances in which the spacecraft may be subjected to special space environment due to operational conditions. Interactions between contaminants and special space environment may alter or greatly increase the contamination effect due to the synergistic effect. This paper will address the various types of contamination generation on orbit, the general effects of the contamination on spacecraft systems, and the typical impacts on the spacecraft operations due to the contamination effect. In addition, this paper will explain the contamination effect induced by the space environment and will discuss the intensified contamination effect resulting from the synergistic effect with the special space environment.

  7. Oral frostbite due to dry ice.

    Science.gov (United States)

    Ohki, Masafumi; Ishikawa, Jyunichi; Kikuchi, Shigeru

    2012-10-01

    Dry ice is a commercially available cryogen that is used worldwide. It may cause frostbite if misused. However, frostbite of the oral cavity due to dry ice has not been previously reported. Here, we describe the first case of dry ice-induced frostbite of the oral cavity. We present a case of oral frostbite due to dry ice and subsequent swelling of the submandibular area and lower lip. We discuss the clinical features of oral frostbite due to volatile substance abuse. Oral frostbite not only may result in the impairment of the affected mucosae directly, but also may adversely affect the tissues in the vicinity of the oral cavity floor indirectly. Oral frostbite may cause edema of the upper airway tract. In case of severe pharyngolaryngeal edema, either tracheal intubation or tracheostomy is necessary. Steroids and antibiotics may be effective in preventing the development of pharyngolaryngeal edema. It is important to bear in mind that volatile substance abuse may possibly induce unusual events. In particular, special attention should be paid to delayed unusual events.

  8. The DUE Globwetland-2 Project

    Science.gov (United States)

    Paganini, Marc; Weise, Kathrin; Fitoka, Eleni; Hansen, Herbert; Fernandez, Diego; Arino, Olivier

    2010-12-01

    The overall objective of the Ramsar convention is the conservation and wise use of wetlands by national actions and international cooperation as a means to achieving sustainable development. This complex and challenging task requires national, local and international bodies involved in the implementation of the convention to rely on suitable geo-information in order to better understand wetland areas, complete national inventories, perform monitoring activities, carry out assessments and put in practice suitable management plans based on up to date and reliable information. In the recent years, the use of satellite earth observations (EO) within innovative geo-spatial analysis has revealed to be a key tool and unique information source to support the environmental community in different application domains, including wetlands conservation and management. The paper presents the main results and findings of the GlobWetland I project, providing an overview of the current capabilities and limits of EO technology as a tool to support the implementation of the Ramsar convention. It also summarises the major recommendations of the GlobWetland symposium "GlobWetland: Looking at Wetlands from Space" which principal aim was to strengthen the links between the different actors involved in the implementation of the Ramsar convention, and the earth observation community, in order to review the state of the art in the use of EO technology for wetlands management. Finally it presents the objective and scope of the GlobWetland II project, which will contribute to the establishment of a Global Wetlands Observing System (G-WOS) in accordance with the Strategic Plan 2009-2015 of the Ramsar convention on wetlands adopted as the last Conference of the Parties. The GlobWetland II project aims principally at developing a G-WOS pilot information system for the production of a number of wetland related geo-information maps and indicators, over 200 wetland sites and surrounding areas

  9. Diabetes due to recurrent pancreatitis secondary to hypercalcemia due to primary hyperparathyroidism

    Directory of Open Access Journals (Sweden)

    Sumit Kumar Chakrabarti

    2013-01-01

    Full Text Available Acute pancreatitis due to hypercalcemia associated with hyperparathyroidism (HPT is not very common. We herein report a case of a 21-year-old woman, who presented with acute pancreatitis. She had a past history of recurrent nephrolithiasis. Subsequent evaluation revealed hypercalcemia (serum calcium: 12.6 mg/dL; low phosphate (2.9 mg/dL with elevated parathyroid hormone (PTH, 156.7 pg/mL and HbA1c (6.9%. Diagnosis of primary HPT (PHPT was made. Recurrent pancreatitis due to hypercalcemia may have resulted in diabetes mellitus.

  10. Crop Insurance Inaccurate FCIC Price Forecasts Increase Program Costs

    National Research Council Canada - National Science Library

    1991-01-01

    ...) how FCIC can improve its forecast accuracy. We found that FCIC's corn, wheat, and soybeans price forecasts exhibit large bias errors that exceed those of other available alternative forecasts and that FCIC would have spent...

  11. US Army Evaluations: A Study of Inaccurate and Inflated Reporting

    Science.gov (United States)

    2012-04-26

    would like to acknowledge the leadership and mentorship that LtCol Shawn P. Callahan, US Marine Corps, provided me throughout the academic year. I also...of dishonesty ." --Nathaniel Hawthorne The NCOER form itself is not to blame for the inflation of NCO evaluations. The.current evaluations have

  12. Operative wound classification: an inaccurate measure of pediatric surgical morbidity.

    Science.gov (United States)

    Gonzalez, Katherine W; Dalton, Brian G; Kurtz, Brendan; Keirsey, Michael C; Oyetunji, Tolulope A; St Peter, Shawn D

    2016-11-01

    Wound classification has catapulted to the forefront of surgical literature and quality care discussions. However, it has not been validated in laparoscopy or children. We analyzed pediatric infection rates based on wound classification and reviewed the most common noninfectious complications which could be a more appropriate measure for quality assessment. We performed a retrospective review of 800 patients from 2011 to 2014 undergoing common procedures at a tertiary pediatric hospital. Demographics, procedure, wound classification and complications were analyzed using descriptive statistics. Infection rates were in the expected low range for clean procedures. However, 5% of pyloromyotomy patients required readmission and 10% of circumcision patients developed penile adhesions; 2% required reoperation. Ostomy reversal, a clean contaminated case, had 17% wound infections, whereas acute appendicitis, a contaminated case had only a 4% infection rate. Laparoscopic cholecystectomy (clean-contaminated or contaminated depending on inflammation) had 2% postoperative infections. Perforated appendicitis, a dirty procedure had an 18% infection rate, below the expected >27% for dirty cases in adults. Current wound classifications do not accurately approximate the risk of surgical site infections in children, particularly for laparoscopic procedures. It would be more appropriate to grade hospitals based on disease and procedure specific complications. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Sound level measurements using smartphone "apps": Useful or inaccurate?

    Directory of Open Access Journals (Sweden)

    Daniel R Nast

    2014-01-01

    Full Text Available Many recreational activities are accompanied by loud concurrent sounds and decisions regarding the hearing hazards associated with these activities depend on accurate sound measurements. Sound level meters (SLMs are designed for this purpose, but these are technical instruments that are not typically available in recreational settings and require training to use properly. Mobile technology has made such sound level measurements more feasible for even inexperienced users. Here, we assessed the accuracy of sound level measurements made using five mobile phone applications or "apps" on an Apple iPhone 4S, one of the most widely used mobile phones. Accuracy was assessed by comparing application-based measurements to measurements made using a calibrated SLM. Whereas most apps erred by reporting higher sound levels, one application measured levels within 5 dB of a calibrated SLM across all frequencies tested.

  14. Integration of inaccurate data into model building and uncertainty assessment

    Energy Technology Data Exchange (ETDEWEB)

    Coleou, Thierry

    1998-12-31

    Model building can be seen as integrating numerous measurements and mapping through data points considered as exact. As the exact data set is usually sparse, using additional non-exact data improves the modelling and reduces the uncertainties. Several examples of non-exact data are discussed and a methodology to honor them in a single pass, along with the exact data is presented. This automatic procedure is valid for both ``base case`` model building and stochastic simulations for uncertainty analysis. 5 refs., 3 figs.

  15. Amazing Stories: Acquiring and Avoiding Inaccurate Information from Fiction

    Science.gov (United States)

    Rapp, David N.; Hinze, Scott R.; Slaten, Daniel G.; Horton, William S.

    2014-01-01

    Authors of fiction need not provide accurate accounts of the world, which might generate concern about the kinds of information people can acquire from narratives. Research has demonstrated that readers liberally encode and rely upon the information provided in fictional stories. To date, materials used to demonstrate these effects have largely…

  16. Using Little's Irregularity Index in orthodontics: outdated and inaccurate?

    LENUS (Irish Health Repository)

    Macauley, Donal

    2012-12-01

    Little\\'s Irregularity Index (LII) was devised to objectively score mandibular incisor alignment for epidemiological studies but has been extended to assess the relative performance of orthodontic brackets, retainer or treatment modalities. Our aim was to examine the repeatability and precision of LII measurements of four independent examiners on the maxillary arch of orthodontic patients. The hypothesis was that the reproducibility of individual contact point displacement measurements, used to calculate the LII score, are inappropriate.

  17. 5 CFR 732.301 - Due process.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Due process. 732.301 Section 732.301...) NATIONAL SECURITY POSITIONS Due Process and Reporting § 732.301 Due process. When an agency makes an... any determination. (b) Comply with all applicable administrative due process requirements, as provided...

  18. Inaccurate Assessment of Canine Body Condition Score, Bodyweight, and Pet Food Labels: A Potential Cause of Inaccurate Feeding.

    Science.gov (United States)

    Yam, Philippa S; Naughton, Gregory; Butowski, Christina F; Root, Amanda L

    2017-06-09

    The objectives were to investigate owners' ability to assign the correct bodyweight (BW) and body condition score (BCS) to their dog and to interpret wet and dry pet food labels by estimating how much to feed daily. One hundred and seventy-four questionnaires were completed. Owner estimated BW was compared to actual BW, correct being defined within ±10% of actual BW. Correct interpretation of the total amount of food required was determined by the number of cans (±25% of cans) required for wet food and grams (±20% of grams) for dry food, based on the dog's actual BW, the feeding guidelines on the label, and a comparison with the owner's estimate. Eleven percent of owners overestimated BCS and 19% overestimated BW. Only 48% of owners could correctly estimate their dog's BW. Only 23% and 43% of owners could correctly estimate how much wet and dry food to feed, respectively. Chi-square analysis demonstrated a significant positive association for owners correctly estimating their dog's BW and interpreting the wet pet food label. Many owners are not aware of their pet's BCS and BW and cannot accurately interpret pet food labels. Further owner education to improve these skills is needed if dogs are to be fed correctly.

  19. Inaccurate Assessment of Canine Body Condition Score, Bodyweight, and Pet Food Labels: A Potential Cause of Inaccurate Feeding

    Directory of Open Access Journals (Sweden)

    Philippa S. Yam

    2017-06-01

    Full Text Available The objectives were to investigate owners’ ability to assign the correct bodyweight (BW and body condition score (BCS to their dog and to interpret wet and dry pet food labels by estimating how much to feed daily. One hundred and seventy-four questionnaires were completed. Owner estimated BW was compared to actual BW, correct being defined within ±10% of actual BW. Correct interpretation of the total amount of food required was determined by the number of cans (±25% of cans required for wet food and grams (±20% of grams for dry food, based on the dog’s actual BW, the feeding guidelines on the label, and a comparison with the owner’s estimate. Eleven percent of owners overestimated BCS and 19% overestimated BW. Only 48% of owners could correctly estimate their dog’s BW. Only 23% and 43% of owners could correctly estimate how much wet and dry food to feed, respectively. Chi-square analysis demonstrated a significant positive association for owners correctly estimating their dog’s BW and interpreting the wet pet food label. Many owners are not aware of their pet’s BCS and BW and cannot accurately interpret pet food labels. Further owner education to improve these skills is needed if dogs are to be fed correctly.

  20. Mudança de conduta cirúrgica motivada pela ecocardiografia transesofágica intraoperatória Cambio de conducta quirúrgica motivada por la ecocardiografía transesofágica intraoperatoria Changes in surgical conduct due to the results of intraoperative transesophageal echocardiography

    Directory of Open Access Journals (Sweden)

    Alexander Alves da Silva

    2010-04-01

    ón.BACKGROUND AND OBJECTIVES: Transesophageal echocardiography (TEE is extremely useful in surgeries like valvuloplasty, of the thoracic aorta, and correction of congenital cardiopathies. The low degree of invasiveness and the capacity to aggregate information that can change the course of the surgery are among the advantages of TEE. The objective of this report was to present a case in which the surgical conduct was changed due to a new diagnosis provided by intraoperative transesophageal echocardiography, and to emphasize the importance of using the transesophageal echo in surgeries to correct congenital cardiopathies. CASE REPORT: A 28-year old female, ASA II, with a history of dyspnea progressing from medium to small efforts was referred by another department for elective surgical correction of stenosis of the pulmonary valve diagnosed by transthoracic echocardiography. Intraoperative transesophageal echocardiography showed patent foramen ovale, infundibular stenosis of the right ventricular outlet, and perimembranous subaortic interventricular communication (IVC of 0.4 cm with left to right shunt. After beginning ECC, the above mentioned diagnoses were confirmed and the surgery included closure of the foramen ovale and IVC, and resection of the infundibular stenosis. Intraoperative intercurrences were not observed and the patient was intubated when she was transferred to the intensive care unit. CONCLUSIONS: Transesophageal echocardiography is extremely useful in patients undergoing surgical correction of congenital cardiopathies because, besides helping the hemodynamic management, it can provide new information capable of improving the final result of the surgery.

  1. Operating limitations due to low gas temperature

    Energy Technology Data Exchange (ETDEWEB)

    Bruschi, R.; Ghiselli, W.; Spinazze, M.

    1995-12-31

    A number of projects concerning continental links for the transport of treated natural gas over long distance, both on and offshore, have been implemented during the last few years or are currently being implemented. The long trunklines in North America and subsea trunklines planned or already in operation in the North Sea, are outstanding examples of such long distance transmission of gas in large diameter pipelines operated at high pressure. The development of such network has paid special attention to the effects that low temperature resulting from the transportation process may imply in terms of pipe structural integrity and environmental impact. Scope of this paper is to discuss operating limitations due to low gas temperature. New project scenarios are presented in a brief introduction. The fluido-thermo-dynamic background for the development of low temperatures are outlined. Finally some topics relevant to structural integrity are discussed in particular such as the pipe steel behaviour at low temperature, the prediction techniques of the ice bulb growth around the pipe, the interactions of the cold line with the soil and the consequences due to the differential compliancy of the pipeline towards points of fixity (in-line valves/tees or fixed plants). 30 refs., 22 figs., 1 tab.

  2. Ratchet due to broken friction symmetry

    DEFF Research Database (Denmark)

    Norden, Bengt; Zolotaryuk, Yaroslav; Christiansen, Peter Leth

    2002-01-01

    A ratchet mechanism that occurs due to asymmetric dependence of the friction of a moving system on its velocity or a driving force is reported. For this kind of ratchet, instead of a particle moving in a periodic potential, the dynamics of which have broken space-time symmetry, the system must...... be provided with sonic internal structure realizing such a velocity- or force-friction dependence. For demonstration of a ratchet mechanism of this type, an experimental setup (gadget) that converts longitudinal oscillating or fluctuating motion into a unidirectional rotation has been built and experiments...... with it have been carried out. In this device, an asymmetry of friction dependence on an applied force appears, resulting in rectification of rotary motion, In experiments, our setup is observed to rotate only in one direction, which is in accordance with given theoretical arguments, Despite the setup being...

  3. 34 CFR 602.25 - Due process.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Due process. 602.25 Section 602.25 Education... Required Operating Policies and Procedures § 602.25 Due process. The agency must demonstrate that the procedures it uses throughout the accrediting process satisfy due process. The agency meets this requirement...

  4. Enceladus Results

    Data.gov (United States)

    National Aeronautics and Space Administration — Here are some results from the Spectra Decomposition Algorithm on infrared spectral images of Saturn's moon Enceladus. Figure 1 is the spatial contribution of the...

  5. 1998 results

    International Nuclear Information System (INIS)

    Gadonneix, P.

    1998-01-01

    This document presents the financial and commercial results of Gaz de France (GdF) company for 1998. The following points are presented successively: financial results (budget results, turnover, self-financing capacity, investments, debt situation), commercial results (some remarkable numbers and records, the tertiary and residential market, the industrial market, cogeneration and natural gas for vehicles), the strategy, 1998 realizations and perspectives (the natural gas energy in the 21. century, the development of GdF, the gas distribution and services (development of the French distribution system, export of the know-how, development of services), the transportation and storage systems threw Europe (densification of the pipeline network, the key-position of France, the north-south equilibrium of the distribution network), the natural gas production by GdF, the diversification of supplies, and the main daughter companies abroad). (J.S.)

  6. Stabilization effect of Weibel modes due to inverse bremsstrahlung ...

    Indian Academy of Sciences (India)

    2016-11-04

    Nov 4, 2016 ... Abstract. In this work, the Weibel instability due to inverse bremsstrahlung absorption in laser fusion plasma has been investigated. The stabilization effect due to the coupling of the self-generated magnetic field by Weibel instability with the laser wave field is explicitly showed. The main result obtained in ...

  7. Stabilization effect of Weibel modes due to inverse bremsstrahlung ...

    Indian Academy of Sciences (India)

    In this work, the Weibel instability due to inverse bremsstrahlung absorption in laser fusion plasma has been investigated. The stabilization effect due to the coupling of the self-generated magnetic field by Weibel instability with the laser wave field is explicitly showed. The main result obtained in this work is that the inclusion ...

  8. Research Results

    Science.gov (United States)

    2011-12-01

    Research on Global Carbon Emission and Sequestration NSFC Funded Project Made Significant Progress in Quantum Dynamics Functional Human Blood Protein Obtained from Rice How Giant Pandas Thrive on a Bamboo Diet New Evidence of Interpersonal Violence from 129,000 Years Ago Found in China Aptamer-Mediated Efficient Capture and Release of T Lymphocytes on Nanostructured Surfaces BGI Study Results on Resequencing 50 Accessions of Rice Cast New Light on Molecular Breeding BGI Reports Study Results on Frequent Mutation of Genes Encoding UMPP Components in Kidney Cancer Research on Habitat Shift Promoting Species Diversification

  9. A Patient Developed Painful Muscle Cramps due to Overeating Mangos

    Science.gov (United States)

    Abe, Kazuo

    2012-01-01

    A 79-year-old woman had a habit to eat a mango every night before sleep and experienced muscle cramps during sleep. Her muscle cramps may be resulted from potassium overload due to overeating mangos. PMID:23091750

  10. Sound Attenuation in Quark Matter Due to Pairing Fluctuations

    Directory of Open Access Journals (Sweden)

    Kerbikov Boris

    2016-01-01

    Full Text Available The sound wave in dense quark matter is subject to strong absorption due to diquark field fluctuations above Tc. The result is another facet of Mandelshtam-Leontovich slow relaxation time theory.

  11. A Patient Developed Painful Muscle Cramps due to Overeating Mangos

    Directory of Open Access Journals (Sweden)

    Kazuo Abe

    2012-01-01

    Full Text Available A 79-year-old woman had a habit to eat a mango every night before sleep and experienced muscle cramps during sleep. Her muscle cramps may be resulted from potassium overload due to overeating mangos.

  12. Potential for erroneous interpretation of poisoning outcomes due to changes in National Poison Data System reporting.

    Science.gov (United States)

    Anderson, Bruce; Ke, Xuehua; Klein-Schwartz, Wendy

    2010-08-01

    In 2006, the annual report of poison centers in the United States changed the method of reporting profiles for generic substance categories from all exposures to single-substance exposures only. The objective of this study is to describe the potential impact of this reporting change on longitudinal analysis of outcomes. Generic substance categories with data available for all years of the study were manually extracted from Table 22 of the National Poison Data System (NPDS) annual reports for 2002-2007. For each generic substance category, the following data were extracted for each of the 6 years: total number of substance mentions (2002-2005) or single-substance exposures (2006-2007), reason (unintentional or intentional), pediatric exposures (children age average annual number of reported deaths by substance category decreased by 80.8%, from 2,229 in year 2002-2005 to 428 after the 2006 reporting change (p average annual number of reported major outcomes by substance category dropped by 76.0% (p average number of deaths and major effects by substance category decreased by about 50% from 394 and 4,639 per year during 2002-2005 to 198 deaths (p average rates of reported deaths (61.7 and 35.9%) and major effects (36.3 and 11.2%) for drug categories and nondrug categories, respectively (p change in 2006 will yield inaccurate results if the change in reporting methodology is not taken into account.

  13. Nanoscale hotspots due to nonequilibrium thermal transport

    International Nuclear Information System (INIS)

    Sinha, Sanjiv; Goodson, Kenneth E.

    2004-01-01

    Recent experimental and modeling efforts have been directed towards the issue of temperature localization and hotspot formation in the vicinity of nanoscale heat generating devices. The nonequilibrium transport conditions which develop around these nanoscale devices results in elevated temperatures near the heat source which can not be predicted by continuum diffusion theory. Efforts to determine the severity of this temperature localization phenomena in silicon devices near and above room temperature are of technological importance to the development of microelectronics and other nanotechnologies. In this work, we have developed a new modeling tool in order to explore the magnitude of the additional thermal resistance which forms around nanoscale hotspots from temperatures of 100-1000K. The models are based on a two fluid approximation in which thermal energy is transferred between ''stationary'' optical phonons and fast propagating acoustic phonon modes. The results of the model have shown excellent agreement with experimental results of localized hotspots in silicon at lower temperatures. The model predicts that the effect of added thermal resistance due to the nonequilibrium phonon distribution is greatest at lower temperatures, but is maintained out to temperatures of 1000K. The resistance predicted by the numerical code can be easily integrated with continuum models in order to predict the temperature distribution around nanoscale heat sources with improved accuracy. Additional research efforts also focused on the measurements of the thermal resistance of silicon thin films at higher temperatures, with a focus on polycrystalline silicon. This work was intended to provide much needed experimental data on the thermal transport properties for micro and nanoscale devices built with this material. Initial experiments have shown that the exposure of polycrystalline silicon to high temperatures may induce recrystallization and radically increase the thermal

  14. Comment on"Air Emissions Due to Wind and Solar Power" and Supporting Information

    Energy Technology Data Exchange (ETDEWEB)

    Mills, Andrew D.; Wiser, Ryan H.; Milligan, Michael; O' Malley, Mark

    2009-03-18

    block of power ignores the benefits of diversity. In real power systems, operators are required to balance only the net variations of all loads and all generators, not the output of individual loads or generators; doing otherwise would ensure an enormous amount of unnecessary investment and operating costs. As a result, detailed studies that aggregate the variability of all loads and generators to the system level find that the amount of operating reserves required to reliably integrate variable resources into the grid are on the order of 10% of the nameplate capacity of the variable generators, even when upto25%of gross demand is being met by variable generation. The authors implicit assumption that incremental operating reserves must be 100% of the nameplate capacity of the variable generation, and be available at all times to directly counter that variability, excludes the option of decommitting conventional units when the load net of variable generation is low. In real power systems, generation response to wind variation can typically be met by a combination of committed units, each operating at a relatively efficient point of their fuel curves. In the Supporting Information, we conceptually demonstrate that the CO{sub 2} and NO{sub x} efficiency penalty found by the authors can be significantly reduced by considering the unit commitment decision with just five plants. Real systems often have tens to hundreds of plants that can be committed and decommitted over various time frames. Ignoring the flexibility of the unit commitment decision therefore leads to unsupportable results. Anumber of analyses of the fuel savings and CO{sub 2} emission benefits of variable generation have considered realistic operating reserve requirements and unit commitment decisions in models that include the reduction in part load efficiency of conventional plants. The efficiency penalty due to the variability of wind in four studies considered by Gross et al. is negligible to 7%, for up to

  15. (ajst) intersystem interference due to hydrometeor

    African Journals Online (AJOL)

    at the three locations are used to predict interference levels with the probability of occurrence ranging from 1-10-3%. The attenuation of the signals due to rain was evaluated using the Power law relationship between attenuation and rain rate, while attenuation due to atmospheric gases was calculated using the ITU-R Rec.

  16. Dermatoses due to indian cultural practices

    Directory of Open Access Journals (Sweden)

    Divya Gupta

    2015-01-01

    Full Text Available A wide prevalence of socio-religious and cultural practices in the Asian subcontinent often leads to multitude of skin diseases which may be missed by the dermatologists because of a lack of awareness. ′Henna′ use causes IgE-mediated hypersensitivity reactions and contact dermatitis. ′Kumkum′ application can result in pigmented contact dermatitis and lichen planus pigmentosus. Sticker ′bindis′ and ′alta′ induce contact leukoderma. Irritant and allergic contact dermatitis occurs after playing with ′Holi′ colors. Threading and drawstring dermatitis lead to koebnerization of pre-existing dermatoses, infections and even squamous cell carcinoma of skin. Mild irritant reactions and contact sensitization occur secondary to balm and hair oil use. ′Mudichood′ represents the comedogenic effect of hair oils combined with occlusion and humidity. Aromatherapy oils can cause contact dermatitis and photosensitive reactions. Heavy metal and steroid toxicity along with severe cutaneous adverse effects like erythroderma can occur as a consequent to the use of alternative medicines. Squamous cell carcinoma due to chronic heat exposure from the heating device "kangri" is seen in Kashmiris. Prayer nodules in Muslims and traction alopecia in Sikhs illustrate how religious practices can negatively affect the skin. With increasing globalization and migration, the practice of indigenous customs and traditions is no longer limited to regional territories, making it imperative for the dermatologists to be acquainted with the cutaneous side effects they can cause.

  17. Lead nephropathy due to Sindoor in India.

    Science.gov (United States)

    Kute, Vivek B; shrimali, Jigar D; Balwani, Manish R; Godhani, Umesh R; Vanikar, Aruna V; Shah, Pankaj R; Gumber, Manoj R; Patel, Himanshu V; Trivedi, Hargovind L

    2013-07-01

    We report a case of lead nephropathy due to Sindoor treated successfully with steroid, hemodialysis and chelating agent. Diagnosis of lead nephropathy was confirmed by identification of potential sources of lead exposure (Sindoor, 5-10 gm per year for 11 years) indicated by high blood lead level, 95 µg/dL and presence of extrarenal features of lead poisoning (hypertension, anemia, lead line, hyperuricemia). A search for the underlying systemic causes of renal failure yielded no results. A kidney biopsy showed acute or chronic tubule-interstitial nephritis with mesangioproliferative glomerulonephritis with no immune deposit on immunofluorescence consistent with lead nephropathy. He was discharged in good health after psychiatric consultation and continued with oral D-Penicillamine with normal renal function tests and urine output. This case identifies Sindoor as a potential lead exposure among Indians and clinicians should be aware of this risk factor and enquire about it when searching a source of lead exposure in high-risk population.

  18. Catatonia due to systemic lupus erythematosus

    Directory of Open Access Journals (Sweden)

    Francisco de Assis Pinto Cabral Júnior Rabello

    2014-07-01

    Full Text Available Objectives Discuss neuropsychiatric aspects and differential diagnosis of catatonic syndrome secondary to systemic lupus erythematosus (SLE in a pediatric patient. Methods Single case report. Result A 13-year-old male, after two months diagnosed with SLE, started to present psychotic symptoms (behavioral changes, hallucinations and delusions that evolved into intense catatonia. During hospitalization, neuroimaging, biochemical and serological tests for differential diagnosis with metabolic encephalopathy, neurological tumors and neuroinfections, among other tests, were performed. The possibility of neuroleptic malignant syndrome, steroid-induced psychosis and catatonia was also evaluated. A complete reversal of catatonia was achieved after using benzodiazepines in high doses, associated with immunosuppressive therapy for lupus, which speaks in favor of catatonia secondary to autoimmune encephalitis due to lupus. Conclusion Although catatonia rarely is the initial clinical presentation of SLE, the delay in recognizing the syndrome can be risky, having a negative impact on prognosis. Benzodiazepines have an important role in the catatonia resolution, especially when associated with parallel specific organic base cause treatment. The use of neuroleptics should be avoided for the duration of the catatonic syndrome as it may cause clinical deterioration.

  19. Decreased pain sensitivity due to trimethylbenzene exposure ...

    Science.gov (United States)

    Traditionally, human health risk assessments have relied on qualitative approaches for hazard identification, often using the Hill criteria and weight of evidence determinations to integrate data from multiple studies. Recently, the National Research Council has recommended the development of quantitative approaches for evidence integration, including the application of meta-analyses. The following hazard identification case study applies qualitative as well as meta-analytic approaches to trimethylbenzene (TMB) isomers exposure and the potential neurotoxic effects on pain sensitivity. In the meta-analytic approach, a pooled effect size is calculated, after consideration of multiple confounding factors, in order to determine whether the entire database under consideration indicates that TMBs are likely to be a neurotoxic hazard. The pain sensitivity studies included in the present analyses initially seem discordant in their results: effects on pain sensitivity are seen immediately after termination of exposure, appear to resolve 24 hours after exposure, and then reappear 50 days later following foot-shock. Qualitative consideration of toxicological and toxicokinetic characteristics of the TMB isomers suggests that the observed differences between studies are due to testing time and can be explained through a complete consideration of the underlying biology of the effect and the nervous system as a whole. Meta-analyses and –regressions support this conclus

  20. Intracardiac lead endocarditis due to Staphylococcus lugdunensis.

    Science.gov (United States)

    Chopra, Anish; Gulati, Dhiraj; Woldenberg, Nina; Singh, Mamta

    2010-09-01

    Staphylococcus Lugdunensis is a rare but potentially aggressive pathogen in the family of coagulase negative staphylococcus (CoNS). It can cause a wide variety of infections ranging from superficial skin to fulminant infections like endocarditis. Both native and prosthetic valve endocarditis due to S. lugdunensis have been documented in the English literature. Eight cases of pacemaker lead endocarditis due to S. lugdunensis have been described so far. We present the ninth case of pacemaker lead and first case of automatic implantable cardioverter defibrillator (AICD) lead endocarditis due to S. lugdunensis. Copyright © 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  1. Two percolation thresholds due to geometrical effects: experimental and simulated results

    International Nuclear Information System (INIS)

    Nettelblad, B; Martensson, E; Oenneby, C; Gaefvert, U; Gustafsson, A

    2003-01-01

    The electrical properties of a mixture of ethylene-propylene-diene monomer rubber and silicon carbide (SiC) have been measured as a function of filler concentration. It was found that mixtures containing angular SiC grains have a conductivity that displays not one, but two percolation thresholds. Different types of contacts between the conducting particles, being represented by edge and face connections, respectively, can explain the phenomenon. The two percolation thresholds are obtained at volume fractions of about 0.25 and 0.40, respectively. These values are higher than those predicted by theory, which can be explained by dispersion effects with only one phase being granular and the other being continuous. The value of the conductivity at the central plateau was found to be close to the geometric mean of the limiting conductivities at low and high concentrations. This is in good agreement with theory. With rounded SiC grains only one threshold is obtained, which is consistent with only one type of contact. The concentration dependence of the conductivity was simulated using a three-dimensional impedance network model that incorporates both edge and face contacts. The double-threshold behaviour also appears in the calculations. By dispersing the conducting particles more evenly than random, the thresholds are shifted towards higher concentrations as observed in the experiments

  2. Study of bantam miRNA expression in brain tumour resulted due to ...

    Indian Academy of Sciences (India)

    2017-06-19

    Jun 19, 2017 ... Disturbance of delicate concordance between stem cell proliferation, specification and differentiation during brain development leads to several neural disorders including tumours. Accumulating evidences have demonstratedinvolvement of short noncoding microRNAs (miRNAs) in governing several ...

  3. Unilateral plea bargain as a logical result of the Brazilian due process’s constitucional guidelines

    Directory of Open Access Journals (Sweden)

    Marcos Paulo Dutra Santos

    2017-03-01

    Full Text Available This article analyzes the possibility of an unilateral plea bargain, not depending on a previous agreement with the prosecution. From the comparative study between the American and Italian bargained criminal justice and the one practiced in Brazil, it reveals the acceptance of this type of cooperation, according to the nature of the benefits involved, as a natural and inevitable consequence of the constitutional principles that guide Brazilian Criminal Procedure Law.

  4. Study of bantam miRNA expression in brain tumour resulted due to ...

    Indian Academy of Sciences (India)

    Disturbance of delicate concordance between stem cell proliferation, specification and differentiation during brain development leads to several neural disorders including tumours. Accumulating evidences have demonstratedinvolvement of short noncoding microRNAs (miRNAs) in governing several biological as well as ...

  5. Study of bantam miRNA expression in brain tumour resulted due to ...

    Indian Academy of Sciences (India)

    ANIMESH BANERJEE

    2017-06-19

    Jun 19, 2017 ... Abstract. Disturbance of delicate concordance between stem cell proliferation, specification and differentiation during brain development leads to several neural disorders including tumours. Accumulating evidences have demonstrated involvement of short noncoding microRNAs (miRNAs) in governing ...

  6. Pulmonary Hypertension Due to Left Ventricular Cardiomyopathy: Is it the Result or Cause of Disease Progression?

    Science.gov (United States)

    Adusumalli, Srinath; Mazurek, Jeremy A

    2017-12-01

    The purpose of this review is to define pulmonary hypertension in the setting of left heart disease (PH-LHD), discuss its epidemiology and pathophysiology, and highlight the cause and effect relationship it has with disease progression in the setting of cardiomyopathy. Both pulmonary hypertension (PH) and heart failure are becoming increasingly common. As such, PH-LHD is now the most common form of PH. The pathophysiology of the condition relates to backward transmission of elevated left ventricular filling pressures into the pulmonary circulation and, ultimately, right ventricular (RV) strain/dysfunction. It is evident that these pathophysiologic processes are both the effect and cause of left heart disease progression. In this review, we describe the complex relationship between disease progression in left ventricular cardiomyopathy and PH-LHD. Clinicians and researchers should take note of the importance of PH-LHD and RV dysfunction to appropriately risk stratify patients and develop therapies for the condition.

  7. Fidaxomicin in the treatment of colitis due to Clostridium difficile: preliminary results

    Directory of Open Access Journals (Sweden)

    Francesco Cortese

    2014-12-01

    Full Text Available The incidence of Clostridium difficile infections (CDI and Clostridium difficile-Associated Diarrhea (CDAD is increasing in Canada, USA, and Europe and represents a considerable clinical problem. Both naïve and hypervirulent strains can be considered as opportunistic bacteria affecting immunocompromised, antibiotic-treated, critical, or subcritical patients with a microbiota disruption. CDI arising is strictly related to antibiotic, single or combined, and/or proton pump inhibitor treatment. CDI can cause a syndrome with systemic involvement and complex treatment, sometimes requiring surgical interventions (e.g. colectomy in fulminant colitis. Antibiotic treatment with metronidazole by mouth is the first choice and generally vancomycin is administered in case of lack of effectiveness. Fidaxomicin is a new macrocyclic antibiotic for C. difficile with microflora-sparing properties. This paper reports our initial experience in 11 patients with non-responder or relapsing CDIs. Fidaxomicin was effective in 10 cases (91%. Only one patient with an active ulcerative colitis did not respond and was treated with fecal-microbiota transplantation. In two patients diarrhea persisted, but just the ulcerative colitis one was C. difficile-related. No adverse events were experienced.http://dx.doi.org/10.7175/cmi.v8i1s.956

  8. Correction of moderate secondary mitral regurgitation due to aortic valve disease: immediate results

    Directory of Open Access Journals (Sweden)

    В. М. Назаров

    2015-10-01

    Full Text Available To evaluate the impact of surgical strategy in concomitant mitral valve surgery or isolated aortic valve replacement (AVR in patients with moderate secondary mitral regurgitation (MR, 1 574 patients underwent AVR over a period from January 2003 to December 2011. 241 patients had secondary MR 2+ and constituted the study population. Patients were stratified into two groups, those without concomitant mitral valve surgery (Group A, n = 113 and with it (Group B, n = 128. It was found out that AVR plastic correction of MI reduces its recurrence during short-term follow-up but increases the intervention time leading to an insignificant rise in lethality. In patients with aortic stenosis the age exceeding 70 years and the presence of atrial fibrillation are found to be the most significant predictors of preservation of residual mitral regurgitation in the early postoperative period, while more indicative for patients with aortic insufficiency is the presence of tricuspid regurgitation grade 2 or higher.

  9. Brain injury due to anaphylactic shock as a result of formocresol used during root canal treatment.

    Science.gov (United States)

    Ding, Y-J; Song, H; Liu, J-H; Wang, G-H

    2013-10-01

    Formocresol is still used in many parts of the world despite concerns over its toxicity. A case of a 45-year-old women who experienced brain injury after an analyphlactic reaction to formocresol is presented. During routine root canal treatment, the patient experienced nausea and vomiting after formocresol was used as an antibacterial agent in the pulp chamber. The procedure was discontinued and the symptoms resolved. Four days later, the treatment was continued by a different dentist, and the patient developed anaphylactic shock within 10 min of placement of a formocresol-soaked cotton pellet. She received emergency medical treatment and magnetic resonance imaging (MRI) revealed brain injury characterized by swelling of the gyrus in the cerebral watershed territory of the left parietal-occipital lobe. The patient subsequently made a full recovery after supportive treatment. A type-I allergic reaction can be induced by formocresol. The reasons for the brain injury are thought to be cerebral hypoxia, which was induced by the anaphylactic shock and/or cerebral parenchymal oedema. All dentists should be aware of the risks involved in the use of formocresol and avoid using materials containing formocresol and related agents. © 2013 International Endodontic Journal. Published by John Wiley & Sons Ltd.

  10. Facial nerve palsy due to birth trauma

    Science.gov (United States)

    Seventh cranial nerve palsy due to birth trauma; Facial palsy - birth trauma; Facial palsy - neonate; Facial palsy - infant ... to this condition. Some factors that can cause birth trauma (injury) include: Large baby size (may be ...

  11. Cutaneous human myiasis due to Dermatobia hominis.

    Science.gov (United States)

    Suite, M; Polson, K

    2007-10-01

    This is a case report of cutaneous myiasis due to Dermatobia hominis in a female physician who had travelled to Belize. Cutaneous myiasis is endemic in Central and South America but is seldom reported from the Caribbean islands.

  12. Colonic urticaria pattern due to early ischemia

    Energy Technology Data Exchange (ETDEWEB)

    Greenberg, H.M.; Goldberg, H.I.; Axel, L.

    1981-05-15

    The unusual radiographic pattern of bleb-like mounds on the surface of the colon mucosa, previously described as colonic urticaria, was seen in 3 patients in whom no allergic state was present. This urticaria-like pattern was due to colonic distention in all 3, and represented only submucosal edema on the gross and microscopic specimens. We hypothesize that this pattern is due to early changes of ischemia caused by colon distention.

  13. Greenhouse effect due to atmospheric nitrous oxide

    Science.gov (United States)

    Yung, Y. L.; Wang, W. C.; Lacis, A. A.

    1976-01-01

    The greenhouse effect due to nitrous oxide in the present atmosphere is about 0.8 K. Increase in atmospheric N2O due to perturbation of the nitrogen cycle by man may lead to an increase in surface temperature as large as 0.5 K by 2025, or 1.0 K by 2100. Other climatic effects of N2O are briefly discussed.

  14. Change of minerals due to external radiation

    International Nuclear Information System (INIS)

    Krickl, R.

    2009-01-01

    The thesis contains new results on radio-induced alteration in solids, presenting investigations on alpha-particle haloes in several minerals (chlorite, muscovite, biotite, cordierite, diamond, fluorite, quartz, feldspars) and results of artificial irradiation experiments (with He 2+ and O 6+ ions, electrons and gamma-rays) on natural and synthetic crystals and glasses. Samples were characterised using modern micro- and nano-techniques: spectroscopic methods (Raman, PL, CL, IR, UV-VIS-NIR, EELS, EPR), microscopy (polarisation microscopy, SEM, TEM), diffraction (SAED, PXRD, SXRD) and chemical analysis (EDX, WDX, in addition TG). Furthermore, the presented work yields a comprehensive literature review of investigations on radiohaloes (from 1873 until present day) and is completed by results of mathematical modelling and Monte-Carlo-simulations of the interaction of radiation with matter. In all cases, there was very good agreement between measured penetration depths of irradiated particles and radiohalo radii on the one hand and particle ranges calculated by Monte-Carlo-simulations on the other hand. The phenomena of either inexplicably small or large radiohaloes (so called dwarf or giant haloes) reported in the literature could be explained using geometrical models and simulations. For the first time, radiohaloes in muscovite were analysed by spectroscopic methods. A comparison with haloes in chlorite and biotite showed that alpha-induced effects are similar in all investigated sheet silicates: It was observed in all cases that there is no amorphization but merely radio-induced disturbance of the short range order (due to accumulation of point defects). Changes of the coloration of sheet silicates are not caused by distinct additional absorption bands but by a shift of the high-energy absorption edge into the visible range. By obtaining spectra from different regions within haloes, it was possible to reconstruct the dose-dependent evolution of radio-induced light

  15. Rapidly progressive dementia due to neurosarcoidosis

    Directory of Open Access Journals (Sweden)

    Gabriela Carneiro C. Fortes

    Full Text Available ABSTRACT Rapidly progressive dementia (RPD is typically defined as a cognitive decline progressing to severe impairment in less than 1-2 years, typically within weeks or months. Accurate and prompt diagnosis is important because many conditions causing RPD are treatable. Neurosarcoidosis is often cited as an unusual reversible cause of RPD. Methods: We report two cases of neurosarcoidosis presenting as RPD. Results: Case 1: A 61-year-old woman developed a RPD associated with visual loss. In seven months she was dependent for self-care. Magnetic resonance imaging (MRI revealed temporal and suprasellar brain lesions. Treatment with high-dose intravenous prednisolone was associated with partial improvement. Case 2: A 43-year-old woman who was being treated for diabetes insipidus developed a severe episodic amnesia one year after onset of cognitive symptoms. Previous MRI had shown a hypothalamic lesion and she had been treated with oral prednisone and cyclophosphamide. There was reduction of the MRI findings but no improvement in the cognitive deficits. Brain biopsy disclosed noncaseous granulomas and granulomatous angiitis; treatment was changed to high-dose intravenous methylprednisolone, with poor symptomatic response. Conclusion: The diagnosis of RPD due to neurosarcoidosis can be challenging when the disease is restricted to the nervous system. In these cases, clinical presentation of RPD associated with neuroendocrine and visual dysfunction, imaging findings showing hypothalamic lesions and, in some cases, brain biopsy, are the key to a correct diagnosis. It is possible that earlier diagnoses and treatment could have led to a better outcome in these patients.

  16. Subjeans Condensations due to a Thermal Instability

    Science.gov (United States)

    Opher, R.; Valio, A.

    1990-11-01

    RESUMEN. Las observaciones recientes muestran que las nubes moleculares no son homogeneas, sino que tienen condensaciones. Se observa que estas condensaciones estan libres gravitacionalmente. C6mo se forman estas condensaciones? Sugerimos explicar estas conden sac jones como debidas a que la inestabilidad termica ayuda a la gravedad. Se estudi6 una funci5n de enfriamiento por gramo de la forma general A p T , en donde p y T son la densidad y la temperatura. Estamos interesados en el valor maximo de para la cual el colapso ocurre. Se estudiaron varios mode- los. Nuestros resultados indican que los valores de comparables con aquellos sugeridos por la literatura (1 < son suficientes para provocar el colapso de masas inferiores a la masa de Jeans por medio de inestabilidad termica, ayudada por gravedad y asi se forman las condensaciones libres gravitacionalmente. ABSTRACT: Recent observations show that molecular clouds are not homogeneous, but clumpy. Some clumps are observed to be gravitationally unbound. How did these clumps then form? We suggest explaining these condensation as due to thermal instability aiding gravit y The cooling function per gram studied is of the general form A p T,where pand T are the density and temperature, respectively. We are interested in the maximum value of for which collapse still occurs. Various models are studied. Our results indicate that values comparable to those suggested in the literature (1 < %< 2) are sufficient to trigger the collapse of subjeans masses by thermal instability, when aided by gravity, and form the observed gravitationally unbound clumps. Keq o : HYDRODYNAMICS - INTERSTELLAR CLOUDS

  17. Ocular Injury due to Potassium Permanganate Granules

    Directory of Open Access Journals (Sweden)

    Chareenun Chirapapaisan

    2018-02-01

    Full Text Available Purpose: We report a rare case of ocular injury due to potassium permanganate (KMnO4 granules in a child. Methods: This is a retrospective case report. Results: A 2-year-old boy was transferred to our emergency room with severe pain in his right eye, inflamed eyelids, and brownish stains on his fingers. Chemical injury was suspected. Copious eye irrigation was immediately performed. Diffuse brownish splotches were then observed at the inferior bulbar conjunctiva. Otherwise, systemic organs were intact. Complete eye exam under general anesthesia revealed a 5-mm epithelial defect at the central cornea, along with generalized conjunctival injection and limbal ischemia, inferiorly. Multiple semi-dissolved granules of KMnO4 trapped in the inferior fornix were identified. The chemical particles were gradually washed out and removed; however, the brownish stains remained. The patient received preservative-free steroid, antibiotic eye drops, and lubricants as regular management for mild to moderate degree of ocular burn. Pseudomembrane developed early and transformed into symblepharon within a few days after the injury. Membrane adhesion was lysed, and more aggressive medications were then substituted. Commercial amniotic membrane (PROKERA® was also applied to promote wound healing and to prevent recurrence of symblepharon. The ocular surface was eventually restored, and corneal transparency was preserved. Conclusion: Ocular injury with the granular form of KMnO4 is rare. Its toxicity is comparable to concentrated KMnO4 solution. However, the dissolved particles that had been absorbed in the stained conjunctiva were continuously released and damaged the ocular surface more than we primarily anticipated. Awareness of this condition and prompt management yield a good treatment outcome.

  18. Serology of paracoccidioidomycosis due to Paracoccidioides lutzii.

    Science.gov (United States)

    Gegembauer, Gregory; Araujo, Leticia Mendes; Pereira, Edy Firmina; Rodrigues, Anderson Messias; Paniago, Anamaria Mello Miranda; Hahn, Rosane Christine; de Camargo, Zoilo Pires

    2014-07-01

    Paracoccidioides lutzii is a new agent of paracoccidioidomycosis (PCM) and has its epicenter localized to the Central-West region of Brazil. Serological diagnosis of PCM caused by P. lutzii has not been established. This study aimed to develop new antigenic preparations from P. lutzii and to apply them in serological techniques to improve the diagnosis of PCM due to P. lutzii. Paracoccidioides lutzii exoantigens, cell free antigen (CFA), and a TCA-precipitated antigen were evaluated in immunodiffusion (ID) tests using a total of 89 patient sera from the Central-West region of Brazil. Seventy-two sera were defined as reactive for P. brasiliensis using traditional antigens (AgPbB339 and gp43). Non-reactive sera for traditional antigens (n = 17) were tested with different P. lutzii preparations and P. lutzii CFA showed 100% reactivity. ELISA was found to be a very useful test to titer anti-P. lutzii antibodies using P. lutzii-CFA preparations. Sera from patients with PCM due to P. lutzii presented with higher antibody titers than PCM due to P. brasiliensis and heterologous sera. In western blot, sera from patients with PCM due to P. lutzii were able to recognize antigenic molecules from the P. lutzii-CFA antigen, but sera from patients with PCM due to P. brasiliensis could not recognize any P. lutzii molecules. Due to the facility of preparing P. lutzii CFA antigens we recommend its use in immunodiffusion tests for the diagnosis of PCM due to P. lutzii. ELISA and western blot can be used as complementary tests.

  19. Due diligence duties for an environmental liability

    International Nuclear Information System (INIS)

    Huebsch, M.

    2000-04-01

    Jurisdiction turned out well to create a basic ruling for due diligence duties. These due diligence duties are high standards for the law of torts (outside of contracts) within the Austrian civil law and represent a liability-extension for the holder of the source of danger. They establish an action for injunction in particular for preventing (further) damages. Therewith due diligence duties get a general sense in the range of a civil law for environmental liability. The responsible holder of a danger zone will therefore influence his way of acting to protect potential victims and the environment. The burden of proof is on the plaintiff (victims) under the Civil Code. Victims have specific sources of danger including high endangering special facilities in their argumentation with the so-called prima-facie-proof or first-appearance-proof. A turning back of the presentation of evidence to the polluter is wrong. The polluter himself has a continuing liability for dangerous activities and his clerks in the case of an extremely high danger of damage. All due diligence duties can be arranged in three areas: in information-, danger-avoidance- and danger-prevention-duties. The determination of range and essence of the duties has to be adjusted to each individual case. The range of the specific danger area is the essential link. The intensity of due diligence duties is increasing with the size of danger in the way of a movable system depending on the protected interest. Due diligence duties have to be kept within reasonable limits with two criterions: necessarity and demand. Proportionality of actions is a third criterion to avoid exaggeration of due diligence duties to obtain an effective protection for victims including the environment. (author)

  20. Broadening of the Measured Frequency Spectrum in a Differential Laser Anemometer due to Interference Plane Gradients

    DEFF Research Database (Denmark)

    Hanson, Steen Grüner

    1973-01-01

    It is shown how an inaccurate alignment of a differential laser anemometer may cause a significant broadening of the Doppler spectrum. The reason is the appearance of gradients in the interference pattern in the measuring volume. The phenomenon was investigated theoretically, and a method...

  1. Paraneoplastic Cushing Syndrome Due To Wilm's Tumor.

    Science.gov (United States)

    Faizan, Mahwish; Manzoor, Jaida; Saleem, Muhammad; Anwar, Saadia; Mehmood, Qaiser; Hameed, Ambreen; Ali, Agha Shabbir

    2017-05-01

    Paraneoplastic syndromes are rare disorders that are triggered by an altered immune system response to neoplasm. Paraneoplastic syndromes may be the first or the most prominent manifestations of cancer. Wilm's tumor is the most frequent pediatric renal malignancy and usually presents with abdominal mass. Unusual presentations like acquired von Willebrand disease, sudden death due to pulmonary embolism and Cushing syndrome have been described in the literature. Cushing syndrome, as the presenting symptom of a malignant renal tumor in children, is a very rare entity. Few case reports are available in the literature exploring the option of preoperative chemotherapy as well as upfront nephrectomy. We report a rare case of paraneoplastic Cushing syndrome due to a Wilm's tumor. Based on gradual decrease of postoperative weight, blood pressure, serum adrenocorticotropic hormone, and plasma cortisol levels, along with histological confirmation of Wilm's tumor, paraneoplastic Cushing syndrome due to Wilm's tumor was confirmed.

  2. Scope and limitations of due process in administrative proceedings

    Directory of Open Access Journals (Sweden)

    Bernardo Carvajal Sánchez

    2010-12-01

    Full Text Available In order to explain in a better way the scope of Due Process in Administrative Law as a legal norm whose respect is essential to all government agencies, three points of view (formal, structural and material are proposed. Those items seem useful to understand “Administrative Due Process” in all its dimensions: as a constitutional norm developed by the enactment of laws and decrees; as a principle inspiring some conducts and new norms; and as an objective and subjective fundamental right. On the other hand, it is shown that Administrative Due Process is not an absolute rule because in some cases its full application is subject to normative relativism. Two opposite trends can be perceived at this point: in the first place, government agencies usually do not act the same way judges do, so Administrative Due Process should be distinguished from Judicial Due Process; therefore, it could actually have a more restricted scope. In the second place, some administrative authorities are nowadays playing a role more or less similar to what judges do. This means that new procedural guarantees will be claimed. In any case, admitting valid limitations to Administrative Due Process leads to the quest of the limits of these limitations. The application of the rule of Due Process cannot be totally suppressed; its scope cannot be completely reduced. This is the result of its fundamental nature as a legal norm that ensures justice and equity in all administrative procedures, and proscribes random decisions.

  3. Pseudotumour cerebri syndrome due to cryptococcal meningitis.

    Science.gov (United States)

    Cremer, P D; Johnston, I H; Halmagyi, G M

    1997-01-01

    Three cases are reported of the pseudotumour cerebri syndrome-that is, intracranial hypertension without mass lesion or enlarged ventricles, due to cryptococcal meningitis. In these patients the papilloedema was successfully treated with optic nerve sheath decompression, and the intracranial hypertension with lumboperitoneal CSF shunting. These cases support the concept that pseudotumour cerebri is a syndrome of intracranial hypertension that can be due to any disorder producing obstruction of the CSF pathways at the level of the arachnoid villi. This concept is important because it directs therapy to normalise the intracranial pressure and preserve vision. Images PMID:9010409

  4. Plagiarism Due to Misunderstanding: Online Instructor Perceptions

    Science.gov (United States)

    Greenberger, Scott; Holbeck, Rick; Steele, John; Dyer, Thomas

    2016-01-01

    Plagiarism is an ongoing problem in higher education. This problem exists in both online and face-to-face modalities. The literature indicates that there are three ways higher education institutions define plagiarism, which includes theft, deception, and misunderstanding. Plagiarism due to misunderstanding has received less attention in the…

  5. [Delayed asthma bronchiale due to epoxy resin].

    Science.gov (United States)

    Authried, Georg; Al-Asadi, Haifaa; Møller, Ulla; Sherson, David Lee

    2013-10-28

    Epoxy resin is a low molecular weight agent, which can cause both acute and delayed allergic reactions. However, it is known causing skin reactions with direct or airborne contact. Rarely it can cause airway reactions like asthma bronchiale. We describe a case of a windmill worker who developed delayed asthma bronchiale due to airborne contact with epoxy resin.

  6. Internal dosimetric evaluation due to uranium aerosols

    International Nuclear Information System (INIS)

    Garcia Aguilar Juan; Delgado Avila Gustavo

    1991-01-01

    The present work has like object to carry out the internal dosimetric evaluation to the occupationally exposed personnel, due to the inhalation of aerosols of natural uranium and enriched in the pilot plant of nuclear fuel production of the National Institute of Nuclear Research

  7. Transhorizon Radiowave Propagation due to Evaporation Dueting

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 1. Transhorizon Radiowave Propagation due to Evaporation Ducting - The Effect of Tropospheric Weather Conditions on VHF and UHF Radio Paths Over the Sea. Salil David Gunashekar D R Siddle E M Warrington. General Article Volume 11 ...

  8. Pneumonia and Bacteremia Due to Kytococcus schroeteri

    OpenAIRE

    Blennow, Ola; Westling, Katarina; Fröding, Inga; Özenci, Volkan

    2012-01-01

    Kytococcus schroeteri, a saprophyte of the human skin, may cause serious infections in the immunocompromised host. Here, we describe a case of pneumonia and bacteremia due to Kytococcus schroeteri in an immunocompromised patient, successfully treated with linezolid and trimethoprim-sulfamethoxazole.

  9. Pneumonia and bacteremia due to Kytococcus schroeteri.

    Science.gov (United States)

    Blennow, Ola; Westling, Katarina; Fröding, Inga; Ozenci, Volkan

    2012-02-01

    Kytococcus schroeteri, a saprophyte of the human skin, may cause serious infections in the immunocompromised host. Here, we describe a case of pneumonia and bacteremia due to Kytococcus schroeteri in an immunocompromised patient, successfully treated with linezolid and trimethoprim-sulfamethoxazole.

  10. Nuclear potentials due to pion exchange

    International Nuclear Information System (INIS)

    Robillota, M.R.

    1984-01-01

    The two, three and four nucleon potentials due to the exchange of pions can be accurately calculated by means of chiral symmetry. The comparison of the dynamical content of these potentials allow us to understand the geometrical origin of the hierarchy existing among them. (Author) [pt

  11. Spinal cord compression due to metastases

    International Nuclear Information System (INIS)

    Azevedo, C.M. de; Matushita, J.P.K.; Silva, M.A.F. da; Koch, H.A.

    1986-01-01

    A study of 20 patients with medullary compression syndrome due to lesions not related to the central nervous system is presented. Plain films of the spine and myelography are made to determine the level of osseous involvement, the level of the spinal block and to planning radiotherapy. (Author) [pt

  12. Due diligence responsibilities of the professional geologist

    International Nuclear Information System (INIS)

    Hobbs, G.W.

    1991-01-01

    Whether in the role of independent consultant or company employee, a geologist has certain professional obligations in the evaluation of an oil and gas submittal from a third party. 'Due diligence' is the term used to describe the analysis of an investment opportunity. Due diligence involves a multidisciplinary examination of both the technical and business aspects of a submittal. In addition to the obvious geological considerations, prospect evaluations should include relevant details about the specific technical documentation reviewed, information sources, and how the data were verified. Full disclosure of ownership, technical risks, and negative aspects of the prospect should be included along with the positive elements. After the geological analysis is completed, the economic merits of the prospect should be analyzed, incorporating all lease burdens and terms of participation into the calculations. Estimated exploration, development, and operating costs, together with projected annual production, cash flow, and reserves must be examined as to their reasonableness. Finally, the due diligence review should include a thorough check on the reputation, financial condition, technical and managerial expertise, and prior track record of the operator. Bank, trade, legal, and prior partner references should be contacted. The successful professional geologist in today's competitive world must have multidisciplinary skills. A solid background in geology and geophysics, a basic understanding of the principles of petroleum engineering and economics, and the wits of a private eye are needed for good due diligence work

  13. Dysphagia due to diffuseidiopathic skeletal hyperostosis (DISH ...

    African Journals Online (AJOL)

    Diffuse idiopathic skeletal hyperostosis (DISH) or Forestier's disease isa form of degenerative arthritiswith unique spinal and extra spinal manifestations. Dysphagia due to DISH is uncommon but when present DISH should be suspected. Surgical decompression can relieve some of the symptoms. We report a case of a 60 ...

  14. Recurrent poststernotomy mediastinitis due to histoplasmosis: The ...

    African Journals Online (AJOL)

    This report describes the first case of surgical site infection due to Histoplasma capsulatum. A 4 year-old presented with recurrent thoracotomy surgical site infection (SSI) requiring multiple debridements until the correct diagnosis was performed. This case illustrates the critical role of histopathology in early recognition of ...

  15. Elevated Tank Due to Earthquake Even

    Directory of Open Access Journals (Sweden)

    Kotrasová Kamila

    2017-12-01

    Full Text Available Elevated reservoirs are mainly used for storing of variety water. During earthquake activity the fluid exerts impulsive and convective (sloshing effects on the walls and bottom of tank. This paper provides theoretical background for analytical calculating of elevated water tank due to earthquake even and deals with simplified seismic design procedures for elevated tanks.

  16. Pulsatile Proptosis due to Intraorbital Meningocele

    OpenAIRE

    Rumund, A. van; Verrips, A.; Verhagen, W.I.

    2017-01-01

    We present a case of a 79-year-old man with a non-symptomatic pulsatile proptosis of the left eye. Magnetic resonance imaging revealed a meningocele into the left orbit due to an osseous defect in the orbital roof.

  17. Myocardial infection due to Fusobacterium nucleatum.

    Science.gov (United States)

    Storm, Jeremy C; Ford, Bradley A; Streit, Judy A

    2013-12-01

    Fusobacterium nucleatum is an anaerobic gram-negative bacillus, which inhabits the oropharynx, gastrointestinal tract, and female genital tract. Infections classically affect the head and neck. We report a patient with a myocardial mass due to F. nucleatum, initially thought to be a neoplasm, and discuss anaerobic cardiac infections. © 2013.

  18. Disseminated infections due to Immune Reconstitution Inflammatory ...

    African Journals Online (AJOL)

    Immune Reconstitution Inflammatory Syndromes (IRIS) are exaggerated pathological inflammatory reactions occurring after initiation of highly active antiretroviral therapy (HAART) due to exuberant immune responses to occult or apparent opportunistic infections or cancers. In view of paucity of studies from Nigeria, we ...

  19. Ophthalmoplegia, Dysphonia and Tetraparesis Due to Guillain ...

    African Journals Online (AJOL)

    Guillain-Barre's syndrome (GBS) or inflammatory/post-infectious acute polyradiculoneuropathy is due to demyelination of nerves, causing a progressive paresis or paralysis. It usually begins in the legs and sometimes goes up to the respiratory muscles and cranial nerves. The exact mechanism of GBS occurrance is still ...

  20. AFT Chief Promises Due-Process Reform

    Science.gov (United States)

    Sawchuk, Stephen

    2010-01-01

    The president of the American Federation of Teachers (AFT), Randi Weingarten, is putting the sensitive issue of due process on the education reform table, with a pledge to work with districts to streamline the often-cumbersome procedures for dismissing teachers who fail to improve their performance after receiving help and support. She has also…

  1. Refraction in the lower troposphere: Higher order image distortion effects due to refractive profile curvature

    Science.gov (United States)

    Short, Daniel J.

    There are many applications that rely on the propagation of light through the atmosphere - all of which are subject to atmospheric conditions. While there are obvious processes such as scattering due to particulates like clouds and dust that affect the received intensity of the radiation, the clear atmosphere can also cause significant effects. Refraction is a clear air effect that can cause a variety of phenomena such as apparent relocation, stretching and compression of objects when viewed through the atmosphere. Recently, there has been significant interest in studying the refractive effects for low angle paths within the troposphere, and in particular, near-horizontal paths in the Earth's boundary layer, which is adjacent to the ground. Refractive effects in this case become problematic for many terrestrial optical applications. For example, the pointing of a free space optical communication or a remote sensing system can suffer wandering effects, high-resolution imagery can present distorted and/or dislocated targets, optical tracking of targets can be inaccurate, and optical geodetic surveying accuracy is also very sensitive to the effects of refraction. The work in this dissertation was inspired by data from a time-lapse camera system that collects images of distant targets over a near-horizontal path along the ground. This system was used previously to study apparent diurnal image displacement and this dissertation extends that work by exploring the higher order effects that result from curvature in the vertical refractive index profile of the atmosphere. There are surprisingly few experiments involving atmospheric refractive effects that carefully correlate field data to analytical expressions and other factors such as meteorological data. In working with the time-lapse data, which is comprised of sequences of hundreds or thousands of images collected over durations of weeks or months, it is important to develop straightforward analysis techniques that can

  2. Unfavorable results in replantation

    Directory of Open Access Journals (Sweden)

    Abraham G Thomas

    2013-01-01

    Full Text Available Reattachment of amputated parts of the body (Replantation has become a reality since the first arm replant was carried out six decades ago. Failures were not uncommon in the beginning, leading on to the analysis of the problem and refinements in technique. Improvements in sutures, instrumentation and better microscopes further helped the surgeons to do replantation with better finesse and functional results. Evaluation of results and particularly failure and long term results help the younger surgeons to learn from the difficulties faced earlier to do better in the future. An attempt is made to list various aspects of replantation experienced by the author during the past 30 years, particularly in reference to unfavorable results, which had been occasionally total failure, or a partial failure, with poor function and cosmesis due to infection. An insensate limb with poor function is the result of inadequate or improper nerve coaptation or infection destroying the whole repair. It is apt to mention that infection is mostly the result of poor vascularity due to devitalized tissue. Difficulties arise often in identifying the viable tissue, particularly while debriding in the distal amputated part since there is no bleeding. Experience counts in this, specifically to identify the viable muscle. The factors that may lead to complications are listed with remarks to avoid them.

  3. Transverse deflections in a cavity due to the short-range longitudinal wake

    International Nuclear Information System (INIS)

    Bane, K

    2003-01-01

    Consider an ultra-relativistic electron bunch passing through a (cylindrically symmetric) multi-cell linac cavity that is filled with fundamental mode rf. It is well known that this bunch--on entering the cavity--experiences a focusing kick, and--on exiting the cavity--a defocusing kick, even though the mode is cylindrically symmetric. The effects of these kicks in linacs tend to be significant only in low energy regions. Tracking computer programs such as MAD [1] and LIAR [2] include a simple model of these kicks, one based on calculations of W.H. Panofsky [3]. According to this model the effect is represented by two thin lenses positioned at the ends of the cavity, with the strength of the lenses dependent on the accelerating gradient in the cavity. However, a beam will itself excite wakefields that modify its energy gain in a cavity, a modification that depends also on longitudinal position within the bunch. The program LIAR extends Panofsky's rf kick model to include this modification to the effective gradient experienced by different parts of the beam. In this report we investigate how the wakefields affect the rf cavity kicks. In particular, we are interested in the case when the wakefields are a significant perturbation to the problem, such as when, for example, the beam traverses an empty cavity (one with no rf). In this report we have shown that one can calculate the transverse kicks when one knows the time-dependent variation of the longitudinal wake forces on axis. The variation in gradient due to wakefields, however, will in general differ from that due to normal rf acceleration. In particular, transients at the ends of structures, and--for constant gradient structures--an increase in gradient amplitude from beginning to end of the cavity, will mean that the model of focusing/defocusing edges, used for rf acceleration, will be inaccurate. Finally, we conclude that the method LIAR uses to treat the effect of rf focusing in the presence of wakefields on

  4. Sciatica due to pelvic hematoma: case report

    Directory of Open Access Journals (Sweden)

    Kocaman Umit

    2016-12-01

    Full Text Available Sciatica is defined as pain in the sciatic nerve distribution. The most common reason of sciatica is radiculopathy due to lumbar disc hernia. Other causes can be congenital, acquired, infectious, neoplastic, or inflammatory. The piriformis syndrome is another cause. The pain starts in an insidious manner when the cause of sciatica is an extraspinal tumor. It is intermittent at first but a constant and progressive pain that does not decrease with position or rest gradually develops in all patients. The possibility of an intraabdominal or pelvic mass should always be considered and the relevant tests requested when the cause of the sciatica cannot be explained. We present an 83-year-old male who presented with non-traumatic and non-vascular lumbosacral plexopathy due to a large hematoma in the left adductor muscle following the use of warfarin sodium.

  5. Dose due to {sup 40}K

    Energy Technology Data Exchange (ETDEWEB)

    Escareno J, E.; Vega C, H. R., E-mail: edmundoej@hotmail.com [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Calle Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas (Mexico)

    2011-10-15

    The dose due to {sup 40}K has been estimated. Potassium is one of the most abundant elements in nature, being approximately 2% of the Earth's crust. Potassium has three isotopes {sup 39}K, {sup 40}K and {sup 41}K, two are stable while {sup 40}K is radioactive with a half life of 1.2x10{sup 9} years; there is 0.0117% {sup 40}K-to-K ratio. Potassium plays an important role in plants, animals and humans growth and reproduction. Due to the fact that K is an essential element for humans, {sup 40}K is the most abundant radioisotope in human body. In order to keep good health conditions K must be intake at daily basis trough food and beverages, however when K in ingested above the requirements produce adverse health effects in persons with renal, cardiac and hypertension problems or suffering diabetes. In 89.3% {sup 40}K decays to {sup 40}C through {beta}-decay, in 10.3% decays through electronic capture and emitting 1.46 MeV {gamma}-ray. K is abundant in soil, construction materials, sand thus {gamma}-rays produced during {sup 40}K decay contribute to external dose. For K in the body practically all {sup 40}K decaying energy is absorbed by the body; thus {sup 40}K contributes to total dose in humans and it is important to evaluate its contribution. In this work a set of {sup 40}K sources were prepared using different amounts of KCl salt, a {gamma}-ray spectrometer with a NaI(Tl) was characterized to standardized the sources in order to evaluate the dose due to {sup 40}K. Using thermoluminescent dosemeters the dose due to {sup 40}K was measured and related to the amount of {sup 40}K {gamma}-ray activity. (Author)

  6. A summation due to Ramanujan revisited

    Indian Academy of Sciences (India)

    using Hardy's regularly convergent double series. 2. Hardy's regularly convergent double series. Let N0 be the set of all nonnegative integers. We begin with the following definition due to Hardy [3]. DEFINITION 2.1 (Definition 8.1.4 of [5]). A double series ∑(j,k)∈N2. 0 uj,k of real numbers is said to be regularly convergent if ...

  7. Mandibular osteonecrosis due to bisphosphonate use.

    Science.gov (United States)

    Şalvarcı, Ahmet; Altınay, Serdar

    2015-03-01

    Due to their efficient osteoclastic inhibitor effect in bone metabolism and antiangiogenic activity, bisphosphonates are widely used in many cancer diseases particularly in prostate cancers with bone metastasis, lung cancer, breast cancer and multiple myeloma, as well as in systemic diseases such as osteoporosis, osteopenia, Paget disease and osteogenesis imperfect for the last 13 years. Prostate cancer is a common cancer in males and it is the leading cause of bone metastasis. Mandibular metastasis is rarely encountered during the course of prostate cancer. Mandibular osteonecrosis as well has begun to be observed along with the availability of more efficient and stronger formulations developed following the use of bisphosphonates. Zolendronic acid, which has been used also by our patient, has widely come into practice as a 3(rd) generation bisphosphonate. Because of prostate cancer and widespread bone metastases, our patient has been receiving zolendronic acid with maximum androgen blockage for 4 years. Tomography of the patient, who has undergone intensive treatment because of submandibular abscess, demonstrated extensive osteonecrosis in the fovea sublingual region of the mandible corpus. In large series, although, mandibular osteonecrosis was widely seen due to bisphosphonate use for the metastases of lung and breast cancers, this rate was between 9.6% and 11% for prostate cancer within the series. Although our patient had no mandibular metastasis before, mandibular necrosis was observed due to long-term bisphosphonate use. We are going to present our patient who had this rare complication with his clinical picture.

  8. Burden of disease due to cancer in Spain

    Directory of Open Access Journals (Sweden)

    Pérez-Gómez Beatriz

    2009-01-01

    Full Text Available Abstract Background Burden of disease is a joint measure of mortality and morbidity which makes it easier to compare health problems in which these two components enjoy different degrees of relative importance. The objective of this study is ascertaining the burden of disease due to cancer in Spain via the calculation of disability-adjusted life years (DALYs. Methods DALYs are the sum of years of life lost due to premature mortality and years lost due to disability. World Health Organization methodology and the following sources of data were used: the Mortality Register and Princeton Model Life Table for Years of life lost due to premature mortality and population, incidence estimates (Spanish tumour registries and fitting of generalized linear mixed models, duration (from data of survival in Spain from the EUROCARE-3 study and fitting of Weibull distribution function and disability (weights published in the literature for Years lost due to disability. Results There were 828,997 DALYs due to cancer (20.5 DALYs/1,000 population, 61% in men. Of the total, 51% corresponded to lung, colorectal, breast, stomach and prostate cancers. Mortality (84% of DALYs predominated over disability. Subjects aged under 20 years accounted for 1.6% and those aged over 70 years accounted for 30.1% of DALYs. Conclusion Lung, colorectal and breast cancers are responsible for the highest number of DALYs in Spain. Even if the burden of disease due to cancer is predominantly caused by mortality, some cancers have a significant weight of disability. Information on 2000 burden of disease due to cancer can be useful to assess how it has evolved over time and the impact of medical advances on it in terms of mortality and disability.

  9. Unfavourable results in hypospadias

    Directory of Open Access Journals (Sweden)

    Karoon Agrawal

    2013-01-01

    Full Text Available Hypospadias urethroplasty is considered difficult as the complications and unfavourable results are not uncommon. At the turn of the century, due to a better understanding of applied anatomy of hypospadias, new techniques were developed which significantly brought down the complication rate. However unfavourable results are still disturbing. An algorithm for selection of surgery has been presented. Forty three secondary surgeries were performed over 3 years for correction of unfavourable results. The urethrocutaneous fistula was the most common (21% followed by meatal stenosis (14% and narrow neourethra (14%. Common unfavourable results have been discussed. On the basis of experience with a large number of hypospadias urethroplasty ′tips to avoid or minimise unfavourable results′ have been presented. However, one should assess the final outcome of urethroplasty using hypospadias objective scoring evaluation.

  10. Measured spatial variability of beach erosion due to aeolian processes.

    NARCIS (Netherlands)

    de Vries, S.; Verheijen, A.H.; Hoonhout, B.M.; Vos, S.E.; Cohn, Nicholas; Ruggiero, P; Aagaard, T.; Deigaard, R.; Fuhrman, D.

    2017-01-01

    This paper shows the first results of measured spatial variability of beach erosion due to aeolian processes during the recently conducted SEDEX2 field experiment at Long Beach, Washington, U.S.A.. Beach erosion and sedimentation were derived using series of detailed terrestrial LIDAR measurements

  11. Analytical modeling of pipeline failure in multiphase flow due to ...

    African Journals Online (AJOL)

    This research focuses on the development of a model that can predict pipeline failure due to corrosion in multiphase flows. The role that velocity, density, water cut and other parameters play in predicting corrosion is critically analyzed with Norsok Model. The result shows that velocity plays a key role in corrosion prediction.

  12. Modelling atmospheric temperature rise due to pollutants and its ...

    African Journals Online (AJOL)

    Using a mathematical model we show that temperature increases (warming) as the Hartman number due to pollutant increases. Thus, temperature and pollutants contribute to global warming. We also discuss the implications of the result on agriculture and forestry. Journal of the Nigerian Association of Mathematical ...

  13. Intestinal obstruction in children due to Ascariasis: A tertiary health ...

    African Journals Online (AJOL)

    of worms per mouth or rectum and on x-ray and ultrasonography fi ndings. Only the patients of intestinal obstruction with documented evidence of roundworm infestation were included in the study and were followed for one year. Results: One hundred and three children with intestinal obstruction due to Ascaris lumbricoides

  14. Winging of scapula due to serratus anterior tear

    Directory of Open Access Journals (Sweden)

    Varun Singh Kumar

    2014-10-01

    Full Text Available 【Abstract】Winging of scapula occurs most commonly due to injury to long thoracic nerve supplying serratus anterior muscle. Traumatic injury to serratus anterior muscle itself is very rare. We reported a case of traumatic winging of scapula due to tear of serratus anterior muscle in a 19-year-old male. Winging was present in neutral position and in extension of right shoulder joint but not on "push on wall" test. Patient was managed conservatively and achieved satisfactory result. Key words: Serratus anterior tear; Scapula; Wounds and injuries

  15. Hyperekplexia and trismus due to brainstem encephalopathy

    Science.gov (United States)

    Kellett, M.; Humphrey, P.; Tedman, B.; Steiger, M.

    1998-01-01

    The brainstem is said to be the generator of pathological startle responses due to reticular reflex myoclonus or hyperekplexia. A patient with facial weakness, nystagmus, and pyramidal tract signs had generalised reflex spasms in response to auditory, visual and tactile stimuli which clinically and neurophysiologically resembled hyperekplexia. The case is unusual because as well as hyperekplexia, the patient's initial presentation was with an equally rare manifestation of brainstem pathology—brainstem mediated trismus. The causes of brainstem trismus and exaggerated startle responses are discussed with respect to their underlying mechanisms. 

 PMID:9667574

  16. Pneumonia due to Enterobacter cancerogenus infection.

    Science.gov (United States)

    Demir, Tülin; Baran, Gamze; Buyukguclu, Tuncay; Sezgin, Fikriye Milletli; Kaymaz, Haci

    2014-11-01

    Enterobacter cancerogenus (formerly known as CDC Enteric Group 19; synonym with Enterobacter taylorae) has rarely been associated with human infections, and little is known regarding the epidemiology and clinical significance of this organism. We describe a community-acquired pneumonia case in a 44-year-old female due to E. cancerogenus. Identification and antimicrobial susceptibility of the microorganism was performed by the automatized VITEK 2 Compact system (bioMerieux, France). The clinical case suggests that E. cancerogenus is a potentially pathogenic microorganism in determined circumstances; underlying diseases such as bronchial asthma, empiric antibiotic treatment, wounds, diagnostic, or therapeutic instruments.

  17. Shear flow generation due to electromagnetic instabilities

    International Nuclear Information System (INIS)

    Wakatani, M.; Sato, M.; Hamaguchi, S.; Miyato, N.

    2003-01-01

    Shear flow is the most important ingredient governing nonlinear behavior of many types of plasma instability. Electromagnetic effects on shear flow generation have been studied for an electro- magnetic drift wave called resistive drift-Alfven mode (RDAM) and a global MHD mode called resistive wall mode (RWM). For RDAM it is found that the generated shear flow stabilizes the dominant modes; however, other modes are destabilized. For RWM Maxwell stress due to magnetic fluctuations has a tendency to suppress the poloidal flow near the plasma surface, which gives almost same saturation level, since the shear flow stabilization disappears. (author)

  18. Stretch due to Penile Prosthesis Reservoir Migration

    Directory of Open Access Journals (Sweden)

    E. Baten

    2016-03-01

    Full Text Available A 43-year old patient presented to the emergency department with stretch, due to impossible deflation of the penile prosthesis, 4 years after successful implant. A CT-scan showed migration of the reservoir to the left rectus abdominis muscle. Refilling of the reservoir was inhibited by muscular compression, causing stretch. Removal and replacement of the reservoir was performed, after which the prosthesis was well-functioning again. Migration of the penile prosthesis reservoir is extremely rare but can cause several complications, such as stretch.

  19. Severe haemoptysis due to subclavian arteritis.

    Science.gov (United States)

    Lioulias, A; Misthos, P; Kokotsakis, J; Drosos, O; Karagiannidis, N; Pavlopoulos, D; Mitselou, M

    2012-06-12

    Severe haemoptysis due to infective subclavian arteritis has, to our knowledge, never been documented. We report a case of subclavian arterial vasculitis that eroded into the left lung apex, causing a large intraparenchymal mycotic pseudoaneurysm. The patient presented with high fever and blood expectoration. An emergent left lateral thoracotomy was performed. The inflamed segment of the subclavian artery was resected and continuity was restored with a reversed saphenous vein graft. The postoperative course was uneventful and the patient was discharged on the 10th postoperative day.

  20. Questa è la storia di due ragazzi

    Directory of Open Access Journals (Sweden)

    Maria Lombardo

    2015-07-01

    Full Text Available Questa è la storia di due ragazzi per i quali le speranze di riuscita in una professione artistica come quella dell’attore - già difficile per chiunque - in percentuale erano una su dieci. Forse zero. E invece ce l’hanno fatta: uno a Parigi, l’altro a Roma. Entrambi di colore, entrambi di umili origini, arrivati in Europa come tanti, centinaia di migliaia, nel loro caso non da clandestini. Le storie di Bakary e Federico mostrano come il talento e la fortuna possano vincere le avversità, l’emarginazione, i pregiudizi.

  1. Secondary Sclerosing Cholangitis due to Gallbladder Adenocarcinoma

    Directory of Open Access Journals (Sweden)

    David Sicong Fan

    2013-03-01

    Full Text Available Sclerosing cholangitis is a chronic cholestatic liver disease defined by both inflammatory and fibrotic changes of the biliary tract leading to diffuse stricture formation. This entity exists in both a primary and secondary form. Here we present a rare case of secondary sclerosing cholangitis due to direct metastasis from a gallbladder adenocarcinoma. A 55-year-old morbidly obese male presented electively with a 2-week history of low back pain and scleral icterus for 2 days. He also described severe epigastric pain that worsened postprandially and a 13 kg weight loss over the previous month. The patient denied any personal or familial history of malignancy or prior liver disease. Laboratory evaluation revealed mild elevation of transaminases with moderately elevated alkaline phosphatase and total bilirubin. Imaging included ultrasound and contrast-enhanced computed tomography of the abdomen and pelvis showing multiple large gallstones and a large tissue density mass within the fundus of the gallbladder. Subsequent endoscopic ultrasound was performed revealing celiac and portal lymphadenopathy with fine needle aspirations demonstrating adenocarcinoma. Over the next 15 days, bilirubin progressively increased. Magnetic resonance cholangiopancreatography was unremarkable. Liver biopsy, performed to exclude other etiologies of liver failure, demonstrated biliary cholestasis. Endoscopic retrograde cholangiopancreatography was then performed and an occlusion cholangiogram revealed diffuse multifocal stricturing of the intrahepatic bile ducts and moderate stenosis of the common bile duct without proximal ductal dilatation. Thus secondary sclerosing cholangitis due to gallbladder adenocarcinoma was diagnosed.

  2. Food poisoning due to Salmonella Enteritidis--a case report.

    Science.gov (United States)

    Ogata, Mamoru; Ago, Kazutoshi; Ago, Mihoko; Nakashima, Hiroshi; Hayashi, Takahito

    2009-04-01

    A male in his early seventies complained of abdominal pain and diarrhea at 7h after ingesting a small piece of gratin from a box lunch prepared by a caterer. He was admitted to a hospital, but died 37 h later. Dozens of people who had eaten the same box lunch also complained of diarrhea. All of them recovered after medical treatment. A later investigation demonstrated Salmonella Enteritidis (SE) in the gratin from the box lunch. An autopsy revealed very severe typhloenteritis with edema and submucosal hemorrhage. The digestive tract contained fluid contents without foodstuffs. Bacteriological examination revealed SE in the contents of the lower ileum and large intestine. Based on these findings, we concluded that the cause of death was food poisoning due to SE. In this case, ingesting only a small piece of contaminated food caused fatal food poisoning due to SE. These results emphasize the importance of prevention against food poisoning due to Salmonella, particularly SE.

  3. NAUTILUS recent results

    Science.gov (United States)

    Fafone, V.; Astone, P.; Bassan, M.; Bonifazi, P.; Carelli, P.; Coccia, E.; D'Antonio, S.; Federici, G.; Marini, A.; Minenkov, Y.; Modena, I.; Modestino, G.; Moleti, A.; Pallottino, G. V.; Pizzella, G.; Quintieri, L.; Rocchi, A.; Ronga, F.; Terenzi, R.; Visco, M.; Votano, L.

    The resonant-mass gravitational wave detector NAUTILUS, operated by the ROG collaboration at the INFN Frascati National Laboratories, is in continuous data taking since June 1998 with peak sensitivity of h ~= 3×10-22Hz-1/2. It has recently proven to be capable of recording signals due to the passage of cosmic rays. The results of the latest coincidence analyses between the NAUTILUS data and the cosmic ray signals measured by detectors located above and below NAUTILUS are reported.

  4. Identification of Corrosion Products Due to Seawater and Fresh Water

    Science.gov (United States)

    Gismelseed, A.; Elzain, M.; Yousif, A.; Al Rawas, A.; Al-Omari, I. A.; Widatallah, H.; Rais, A.

    2004-12-01

    Mössbauer and X-ray diffraction (XRD) measurements were performed on corrosion products extracted from the inner surface of two different metal tubes used in a desalination plant in Oman. One of the tubes corroded due to the seawater while the second was corroded due to fresh water. The corrosion products thus resulted due to seawater were scrapped off in to two layers, the easily removable rust from the top is termed outer surface corrosion product and the strongly adhered rust as internal corrosion product. The Mössbauer spectra together with the XRD pattern of the outer surface showed the presence of magnetite (Fe3O4), akaganeite (β-FeOOH), lepidocrocite (γ-FeOOH), goethite (α-FeOOH) and hematite (Fe2O3). The inner surface however showed the presence of akaganite, goethite, and magnetite. On the other hand, the corrosion products due to the fresh water showed only the presence of goethite and magnetite. The mechanism of the corrosion process will be discussed based on the significant differences between the formation of the iron components of the corrosion products due to seawater and the fresh water.

  5. Dysphagia due to Diffuse Idiopathic Skeletal Hyperostosis

    Directory of Open Access Journals (Sweden)

    Masafumi Ohki

    2012-01-01

    Full Text Available Diffuse idiopathic skeletal hyperostosis (DISH is usually asymptomatic. However, rarely, it causes dysphagia, hoarseness, dyspnea, snoring, stridor, and laryngeal edema. Herein, we present a patient with DISH causing dysphagia. A 70-year-old man presented with a 4-month history of sore throat, dysphagia, and foreign body sensation. Flexible laryngoscopy revealed a leftward-protruding posterior wall in the hypopharynx. Computed tomography and magnetic resonance imaging revealed a bony mass pushing, anteriorly, on the posterior hypopharyngeal wall. Ossification included an osseous bridge involving 5 contiguous vertebral bodies. Dysphagia due to DISH was diagnosed. His symptoms were relieved by conservative therapy using anti-inflammatory drugs. However, if conservative therapy fails and symptoms are severe, surgical treatments must be considered.

  6. [Suburethral sling removal due to chronic pain].

    Science.gov (United States)

    Homola, P; Hensel, G; Škorničková, Z; Košťál, M

    2017-01-01

    To point out one possible complication after suburethral tape insertion. To present methods of treatment, especially partial or total removal of the tape. Few successful cases of treatment are shown in case reports. Case report. Department of obstetrics and gynecology, Pardubice hospital. Chronic pain after insertion of suburethral tape is a rare complication. There are several possible causes, such as tape erosion with chronic inflamation, post-colposuspension syndrome, myo-fascial syndrome, nerve damage during tape implantation or due to overproduction of fibrous tissue. Partial or total tape removal is needed when the conservative treatment fails. Patients may remain continent or a new tape is placed. Pain relief is usually complete but there are times when additional treatment is needed. Sling removal is a successful method of treating chronic pain after suburethral tape insertion. Patients describe plain relief and improvement of quality of life.

  7. Ketoacidosis is not always due to diabetes

    Science.gov (United States)

    Chandrasekara, Hemantha; Fernando, Pasan; Danjuma, Mohammed; Jayawarna, Chaminda

    2014-01-01

    Chronic alcoholism is a frequently unrecognised cause of ketoacidosis. Most patients with alcoholic ketoacidosis present with normal or low glucose, but this condition can present with hyperglycaemia. This can lead to misdiagnosis of diabetes ketoacidosis and, therefore, inappropriate treatment with insulin. We describe a 37-year-old Caucasian woman with chronic pancreatitis secondary to excess alcohol consumption, admitted with abdominal pain and vomiting, fulfilling the criteria for diabetes ketoacidosis. She was treated according to diabetes ketoacidosis protocol and experienced a hypoglycaemic attack within an hour of initiation of insulin. On review of her history, she was found to have three similar episodes over the past 12 months. Alcoholic ketoacidosis can present with hyperglycaemia due to relative deficiency of insulin and relative surplus in counter-regulatory stress hormones including glucagon. Awareness of the syndrome with a detailed history helps to differentiate alcohol ketoacidosis from diabetes ketoacidosis and prevent iatrogenic hypoglycaemia. PMID:24569261

  8. Acute Paraplegia due to Thoracic Hematomyelia

    Directory of Open Access Journals (Sweden)

    Aykut Akpınar

    2016-01-01

    Full Text Available Spontaneous intraspinal intramedullary hemorrhage is a rare entity with the acute onset of neurologic symptoms. The etiology of idiopathic spontaneous hematomyelia (ISH is unknown, and there are few published case reports. Hematomyelia is mostly associated with trauma, but the other nontraumatic etiologies are vascular malformations, tumors, bleeding disorders, syphilis, syrinx, and myelitis. MRI is a good choice for early diagnosis. Hematomyelia usually causes acute spinal cord syndrome due to the compression and destruction of the spinal cord. A high-dose steroid treatment and surgical decompression and evacuation of hematoma are the urgent solution methods. We present idiopathic spontaneous hematomyelia of a previously healthy 80-year-old male with a sudden onset of back pain and paraplegia.

  9. Subacute bacterial endocarditis due to Actinobacillus actinomycetemcomitans.

    Science.gov (United States)

    Peters, J; Robinson, F; Dasco, C; Gentry, L O

    1983-01-01

    Sixteen documented cases of Actinobacillus actinomycetemcomitans endocarditis have been reported in the past 15 years. The characteristic granular growth and the fastidious nature and slow-growing character of this organism decrease the yield of positive blood cultures. Two recently observed cases of subacute endocarditis due to Actinobacillus are reported, one in a patient who required surgical intervention for complications of his disease and the other case associated with an aortic prosthetic valve. The first patient had late embolic complications which are commonly seen with Actinobacillus endocarditis. A review of the literature; including a synoptic table with clinical failures, treatment, and outcome is presented. Unless special care is taken to isolate these slow growing organisms, these cases will be misclassified as culture negative endocarditis.

  10. Small Bowel Obstruction due to Intestinal Xanthomatosis

    Directory of Open Access Journals (Sweden)

    L. E. Barrera-Herrera

    2015-01-01

    Full Text Available Vast majority of bowel obstruction is due to postoperative adhesions, malignancy, intestinal inflammatory disease, and hernias; however, knowledge of other uncommon causes is critical to establish a prompt treatment and decrease mortality. Xanthomatosis is produced by accumulation of cholesterol-rich foamy macrophages. Intestinal xanthomatosis is an uncommon nonneoplastic lesion that may cause small bowel obstruction and several cases have been reported in the English literature as obstruction in the jejunum. We report a case of small intestinal xanthomatosis occurring in a 51-year-old female who presented with one day of copious vomiting and intermittent abdominal pain. Radiologic images revealed jejunal loop thickening and inflammatory changes suggestive of foreign body obstruction, diagnostic laparoscopy found two strictures at the jejunum, and a pathologic examination confirmed a segmental small bowel xanthomatosis. This case illustrates that obstruction even without predisposing factors such as hyperlipidemia or lymphoproliferative disorders.

  11. Hypomyelinating Leukodystrophy due to HSPD1 Mutations

    DEFF Research Database (Denmark)

    Kusk, Maria Schioldan; Damgaard, Bodil; Risom, Lotte

    2016-01-01

    The hypomyelinating leukodystrophies (HMLs) encompass the X-linked Pelizaeus-Merzbacher disease (PMD) caused by PLP1 mutations and known as the classical form of HML as well as Pelizaeus-Merzbacher-like disease (PMLD) (Online Mendelian Inheritance in Man [OMIM] 608804 and OMIM 260600) due to GJC2...... mutations. In addition, mutations in at least 10 other genes are known to cause HMLs. In 2008, an Israeli family with clinical and neuroimaging findings similar to those found in PMD was reported. The patients were found to have a homozygous missense mutation in HSPD1, encoding the mitochondrial heat......-shock protein 60 (Hsp60), and the disorder was defined as the autosomal recessive mitochondrial Hsp60 chaperonopathy (MitCHAP-60) disease. We here report the first case of this severe neurodegenerative disease since it was first described. Given the fact that the families carried the same mutation our patient...

  12. Surface wave generation due to glacier calving

    Directory of Open Access Journals (Sweden)

    Stanisław R. Massel

    2013-02-01

    Full Text Available Coastal glaciers reach the ocean in a spectacular process called "calving". Immediately after calving, the impulsive surface waves are generated, sometimes of large height. These waves are particularly dangerous for vessels sailing close to the glacier fronts. The paper presents a theoretical model of surface wave generation due to glacier calving. To explain the wave generation process, four case studies of ice blocks falling into water are discussed: a cylindrical ice block of small thickness impacting on water, an ice column sliding into water without impact, a large ice block falling on to water with a pressure impulse, and an ice column becoming detached from the glacier wall and falling on to the sea surface. These case studies encompass simplified, selected modes of the glacier calving, which can be treated in a theoretical way. Example calculations illustrate the predicted time series of surface elevations for each mode of glacier calving.

  13. Acute aortic regurgitation due to infective endocarditis

    Directory of Open Access Journals (Sweden)

    Claudia M Cortés

    2017-10-01

    Full Text Available Acute aortic regurgitation (AAR due to infective endocarditis (IE is a serious disease and usually requires surgical treatment. Our study aims to compare the clinical, echocardiographic, and microbiological characteristics as well as in-hospital outcome of patients with AAR according to the severity of heart failure (HF and to evaluate predictors of in-hospital mortality in a tertiary centre. In a prospective analysis, we compared patients with NYHA functional class I-II HF (G1 vs. functional class III-IV HF (G2. From 06/92 to 07/16, 439 patients with IE were hospitalized; 86 presented AAR: (G1, 39: 45.4% y G2, 47: 54.7%. The G1 had higher prosthetic IE (43.6% vs. 17%, p 0.01. All G2 patients had dyspnoea vs. 30.8% of the G1 (p < 0.0001. There were no differences in clinical, echocardiographic and microbiological characteristics. Surgical treatment was indicated mainly due to infection extension or valvular dysfunction in G1 and HF in G2. In-hospital mortality was 15.4% vs. 27.7% (G1 and G2 respectively p NS. In multivariate analysis, health care-associated acquisition (p 0.001, negative blood cultures (p 0.004, and functional class III-IV HF (p 0.039 were in-hospital mortality predictors. One-fifth of the patients with EI had AAR. Half of them had severe HF which needed emergency surgery and the remaining needed surgery for extension of the infection and / or valvular dysfunction. Both groups remain to have high surgical and in-hospital mortality. Health care-associated acquisition, negative blood cultures and advanced HF were predictors of in-hospital mortality

  14. Frequency of primary amenorrhea due to chromosomal aberration

    International Nuclear Information System (INIS)

    Jabbar, S.

    2004-01-01

    Objective: To find out the frequency of primary amenorrhea due to chromosomal aberration and the different options available for management. Subjects and Methods: All patients with primary amenorrhea due to chromosomal aberrations were included in study. Patient's detailed history, general physical examination, presence or absence of secondary sexual characteristics, abdominal and pelvic examination finding were noted. Targeted investigations, including ultrasound, hormonal assay, buccal smear and karyotyping results were recorded. The management options were individually tailored with focus n psychological management. Results: Eighteen patients out of 30,000 patients were diagnosed as having primary amenorrhea. Six had primary amenorrhea due to chromosomal aberrations with the frequency of 0.02%. The age at presentation was 20 years and above in 50%. The most common cause was Turner's syndrome seen in 4 out of 6. The presenting symptoms were delay in onset of menstruation in 05 patients and primary infertility in 01 patient. Conclusion: Primary amenorrhea due to chromosomal aberration is an uncommon condition requiring an early and accurate diagnosis. Turner's syndrome is a relatively common cause of this condition. Management should be multi-disciplinary and individualized according to the patient's age and symptom at presentation. Psychological management is very important and counselling throughout treatment is recommended. (author)

  15. Clinical predictors of lacunar syndrome not due to lacunar infarction

    Directory of Open Access Journals (Sweden)

    Comes Emili

    2010-05-01

    Full Text Available Background Lacunar syndrome not due to lacunar infarct is poorly characterised. This single centre, retrospective study was conducted to describe the clinical characteristics of patients with lacunar syndrome not due to lacunar infarct and to identify clinical predictors of this variant of lacunar stroke. Methods A total of 146 patients with lacunar syndrome not due to lacunar infarction were included in the "Sagrat Cor Hospital of Barcelona Stroke Registry" during a period of 19 years (1986-2004. Data from stroke patients are entered in the stroke registry following a standardized protocol with 161 items regarding demographics, risk factors, clinical features, laboratory and neuroimaging data, complications and outcome. The characteristics of these 146 patients with lacunar syndrome not due to lacunar infarct were compared with those of the 733 patients with lacunar infarction. Results Lacunar syndrome not due to lacunar infarct accounted for 16.6% (146/879 of all cases of lacunar stroke. Subtypes of lacunar syndromes included pure motor stroke in 63 patients, sensorimotor stroke in 51, pure sensory stroke in 14, atypical lacunar syndrome in 9, ataxic hemiparesis in 5 and dysarthria-clumsy hand in 4. Valvular heart disease, atrial fibrillation, sudden onset, limb weakness and sensory symptoms were significantly more frequent among patients with lacunar syndrome not due to lacunar infarct than in those with lacunar infarction, whereas diabetes was less frequent. In the multivariate analysis, atrial fibrillation (OR = 4.62, sensorimotor stroke (OR = 4.05, limb weakness (OR = 2.09, sudden onset (OR = 2.06 and age (OR = 0.96 were independent predictors of lacunar syndrome not due to lacunar infarct. Conclusions Although lacunar syndromes are highly suggestive of small deep cerebral infarctions, lacunar syndromes not due to lacunar infarcts are found in 16.6% of cases. The presence of sensorimotor stroke, limb weakness and sudden onset in a patient

  16. Jejunal Diverticular Perforation due to Enterolith

    Directory of Open Access Journals (Sweden)

    Ronaldo Nonose

    2011-08-01

    Full Text Available Jejunal diverticulosis is a rare entity with variable clinical and anatomical presentations. Although there is no consensus on the management of asymptomatic jejunal diverticular disease, some complications are potentially life-threatening and require early surgical treatment. Small bowel perforation secondary to jejunal diverticulitis by enteroliths is rare. The aim of this study was to report a case of small intestinal perforation caused by a large jejunal enterolith. An 86-year-old woman was admitted with signs of diffuse peritonitis. After initial fluid recovery the patient underwent emergency laparotomy. The surgery showed that she had small bowel diverticular disease, mainly localized in the proximal jejunum. The peritonitis was due to intestinal perforation caused by an enterolith 12 cm in length, localized inside one of these diverticula. The intestinal segment containing the perforated diverticulum with the enterolith was removed and an end-to-end anastomosis was done to reconstruct the intestinal transit. The patient recovered well and was discharged from hospital on the 5th postoperative day. There were no signs of abdominal pain 1 year after the surgical procedure. Although jejunal diverticular disease with its complications, such as formation of enteroliths, is difficult to suspect in patients with peritonitis, it should be considered as a possible source of abdominal infection in the elderly patient when more common diagnoses have been excluded.

  17. Liver abscess due to sewing needle perforation.

    Science.gov (United States)

    Jutte, Ewoud; Cense, Huib

    2010-08-03

    A 45-year-old female was admitted to the hospital with a 1-week history of right upper abdominal pain and nausea. Ultrasonography showed a thickened duodenum with infiltration. Subsequent gastroscopy did not reveal any abnormalities. CT scan showed a foreign body perforation at the duodenum and a liver abscess (Fig. 1A,B). A diagnostic laparoscopy was performed. During the operation, the abscess was drained (Fig. 2A,B) and a sewing needle was removed (Fig. 3A,B). The patient claimed to have no recollection of swallowing the needle and made a quick recovery. Although rare, gastrointestinal perforations due to ingested foreign bodies most frequently occur at ileocecal, rectosigmoid, and duodenal regions[1]. Sewing needle perforations into the liver have been reported in children, adults, and psychiatric cases. Symptoms can vary from mild gastric pain to signs of peritonitis[2]. "Wait and see" is recommended for asymptomatic patients with no complications. Symptomatic patients (e.g., liver abscess) need surgical intervention[1,2,3].

  18. Sleep deprivation due to shift work.

    Science.gov (United States)

    Costa, Giovanni

    2015-01-01

    Sleep deprivation due to shift work is related to perturbation of the sleep/wake cycle, associated with the modified activity/rest pattern. This may cause a significant disruption of circadian rhythms of biologic functions, driven by the body clock located in the suprachiasmatic nuclei of the hypothalamus. Shift and night workers have to change sleep times and strategies according to their duty periods; consequently, both sleep length and quality can be considerably affected depending on the variable start and finish times on different shifts. About 10% of night and rotating shift workers, aged between 18 and 65 years, have been estimated to have a diagnosable "shift-work sleep disorder," according to the International Classification of Sleep Disorders, version 2 (ICSD-2). In the long run, this may lead to persistent and severe disturbances of sleep, chronic fatigue and psychoneurotic syndromes, besides being a risk or aggravating factor for accidents, gastrointestinal, cardiovascular, and reproductive disorders, as well as, probably, for cancer. Preventive and corrective actions deal with the organization of shift schedules according to ergonomic criteria, careful health surveillance, appropriate education and training on effective countermeasures, in particular, sleep hygiene and napping. © 2015 Elsevier B.V. All rights reserved.

  19. Homocystinuria due to cystathionine beta synthase deficiency

    Directory of Open Access Journals (Sweden)

    Rao T

    2008-01-01

    Full Text Available A two year-old male child presented with cutis marmorata congenita universalis, brittle hair, mild mental retardation, and finger spasms. Biochemical findings include increased levels of homocysteine in the blood-106.62 µmol/L (normal levels: 5.90-16µmol/L. Biochemical tests such as the silver nitroprusside and nitroprusside tests were positive suggesting homocystinuria. The patient was treated with oral pyridoxine therapy for three months. The child responded well to this therapy and the muscle spasms as well as skin manifestations such as cutis marmorata subsided. The treatment is being continued; the case is reported here because of its rarity. Homocysteinuria arising due to cystathionine beta-synthase (CBS deficiency is an autosomal recessive disorder of methionine metabolism that produces increased levels of urinary homocysteine and methionine It manifests itself in vascular, central nervous system, cutaneous, and connective tissue disturbances and phenotypically resembles Marfan′s syndrome. Skin manifestations include malar flush, thin hair, and cutis reticulata / marmorata.

  20. Septic arthritis due to Streptococcus sanguis.

    Science.gov (United States)

    Mandac, Inga; Prkacin, Ingrid; Matovinović, Mirjana Sabljar; Sustercić, Dunja

    2010-06-01

    Septic arthritis may represent a direct invasion of joint space by various microorganisms, including bacteria, viruses and fungi. Although any infectious agent may cause bacterial arthritis, bacterial pathogens are the most significant because of their rapidly destructive nature. We present a case of septic arthritis in a 56-year old male patient due to Streptococcus viridans which is member of the viridans group streptococci. Patient was admitted to Our Hospital presented as fever of unknown origin, losing more than 30 kg of body weight during couple of months, and anemia of chronic disease as paraneoplastic process. He had long history of arterial hypertension and stroke. There was swelling and pain of the right sternoclavicular joint and precordial systolic murmur in physical status. A large diagnostic panel has been made, computerized tomography (CT) of right sternoclavicular joint showed widening of periarticular soft tissue and loss of clavicular corticalis. Cytologic analysis of synovial fluid showed more than 90% of polymorphonuclear leukocytes. There were no crystals on microscopic examination and Gram stain of fluid was negative. Blood cultures were positive for S. sanguis and there was a consideration about possible periodontal disease. Stomatologic examination verified periapical ostitis and extraction of potential cause of infection has been done. Therapy with benzilpenicilline was followed by the gradual improvement of clinical and laboratory parameters. Although viridans group streptococci and Streptococcus sanguis in particular are rare causes of septic arthritis in native joints, they should be considered in the differential diagnosis of periodontal disease.

  1. Pediatric ischemic stroke due to dengue vasculitis.

    Science.gov (United States)

    Nanda, Subrat Kumar; Jayalakshmi, Sita; Mohandas, Surath

    2014-10-01

    Dengue infection is an important arboviral infection in southeast Asia, especially in India. Neurological manifestations of dengue are increasingly recognized. We report an ischemic stroke due to dengue vasculitis in an 8-year-old child. We present a girl with a short febrile illness followed by episodic severe headache, with gradually progressive hemiparesis and visual impairment. Her brain magnetic resonance imaging revealed multiple infarctions in the anterior and posterior circulation. The magnetic resonance angiogram revealed irregular narrowing of bilateral middle cerebral arteries, right anterior cerebral artery, left posterior cerebral, and bilateral vertebral arteries suggestive of vasculitis. Her dengue serology was strongly positive for immunoglobulin M with 68.9 panbio units. The rest of the evaluation for pediatric stroke was unremarkable. She was treated with intravenous followed by oral corticosteroids and recovered totally with resolution of vasculitis on magnetic resonance angiogram over the next 3 months. This child illustrates possible immune-mediated vasculitis caused by dengue infection which is rather a rare presentation in a child who subsequently recovered well. One should consider dengue in childhood strokes in endemic regions. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Electron diffusion due to electromagnetic field fluctuations

    International Nuclear Information System (INIS)

    Yamagishi, T.

    1986-01-01

    Cross field electron diffusion induced by low frequency electromagnetic field fluctuations is investigated by the test particle approach based on the drift kinetic equation with the number conserving Krook collision term within the limit of quasilinear analysis in slab geometry. The diffusion coefficient is described in terms of a form factor which consists of three portions; the wave number and frequency spectra of density fluctuations, the effect of longitudinal wave-particle interaction, and the transverse dispersion function. The transverse dispersion gives the plasma skin depth as the characteristic scale length, which yields the Alcator-like scaling of the diffusion coefficient. The form factor shows a resonance-like behavior due to the magnetic part of fluctuations at the drift frequency, which indicates the importance of density fluctuations near the frequency in the electromagnetic plasma turbulence. This resonance is enhanced with increasing the plasma pressure, and finally the transition of the Alcator scaling is possible in the case of narrow band turbulence. The transitions of the Alcator scaling by the effect of collision is also derived in the single mode approximation. (author)

  3. Pulmonary hypertension due to left heart disease.

    Science.gov (United States)

    Berthelot, Emmanuelle; Bailly, Minh Tam; Hatimi, Safwane El; Robard, Ingrid; Rezgui, Hatem; Bouchachi, Amir; Montani, David; Sitbon, Olivier; Chemla, Denis; Assayag, Patrick

    Pulmonary hypertension due to left heart disease, also known as group 2 pulmonary hypertension according to the European Society of Cardiology/European Respiratory Society classification, is the most common cause of pulmonary hypertension. In patients with left heart disease, the development of pulmonary hypertension favours right heart dysfunction, which has a major impact on disease severity and outcome. Over the past few years, this condition has been considered more frequently. However, epidemiological studies of group 2 pulmonary hypertension are less exhaustive than studies of other causes of pulmonary hypertension. In group 2 patients, pulmonary hypertension may be caused by an isolated increase in left-sided filling pressures or by a combination of this condition with increased pulmonary vascular resistance, with an abnormally high pressure gradient between arteries and pulmonary veins. A better understanding of the conditions underlying pulmonary hypertension is of key importance to establish a comprehensive diagnosis, leading to an adapted treatment to reduce heart failure morbidity and mortality. In this review, epidemiology, mechanisms and diagnostic approaches are reviewed; then, treatment options and future approaches are considered. Copyright © 2017. Published by Elsevier Masson SAS.

  4. Cutaneous reactions due to antihypertensive drugs

    Directory of Open Access Journals (Sweden)

    Upadhayai J

    2006-01-01

    Full Text Available Out of a total of 1147 patients on antihypertensive drugs, 23 (2.04% developed adverse cutaneous drug reactions (ACDR. The commonest antihypertensive drug group causing ACDR was beta-blockers of which atenolol was the commonest culprit. The second most common group was calcium channel blockers with amlodipine as the commonest offender. The most common patterns of ACDR observed included urticaria followed by lichenoid drug eruption (LDE. We noted 2 new patterns of reactions; (i one patient developed brownish blue pigmentation of nails while on atenolol for 3 years, which resolved in 4 months after withdrawal and (ii another patient on amlodipine for 8 years developed Schamberg′s like purpuric pigmentation, which resolved on withdrawal of drug within 3 months. These findings have not been reported in the literature earlier. This study is presented for paucity of Indian data on ACDR due to antihypertensive drugs, and remarkable advancement in area of cardiovascular and antihypertensive pharmacology and a large number of population taking antihypertensive drugs.

  5. [Airway injuries due to blunt chest trauma].

    Science.gov (United States)

    Okabayashi, Kan; Hamatake, D; Yoshida, Y; Nakajima, H; Shirakusa, T; Yamasaki, S

    2006-10-01

    Although the incidence of blunt chest trauma is very high, the mediastinal tracheobronchial injuries are quite rare. The airway injuries are thought to be one of the most urgent clinical conditions in thoracic surgery, and we are requested to make not only a rapid and sharp diagnosis but also an appropriate treatment plan considering combined injuries. We present 9 cases of tracheobronchial injuries due to blunt chest trauma in recent years. The average age of these patients is 26.1 years, and they are consisted of 6 male and 3 female. The cause of trauma is traffic accident in 7, and occupational crane accident in 2. Bronchoplasty were done in 5 cases (right main bronchus in 2, left main bronchus in 1, trunks intermediate bronchus in 1, and the spur between middle and lower lobe in 1), membranous-tracheoplasty with right pneumonectomy in 1, left pneumonectomy in 1, conservative treatment in 2. Postoperative mortality is occurred in 1 case who was suffering from multiple injuries including severe head injury and contralateral lung contusion. Tracheobronchial plasties should be chosen if possible to preserve lung function for the patient suffering from airway injuries.

  6. Epileptic seizures due to multiple cerebral cavernomatosis

    Directory of Open Access Journals (Sweden)

    Spasić Mirjana

    2007-01-01

    Full Text Available Background. Cavernous angiomas are angiographically occult vascular malformations that are present in 0.4−0.9 % of people, and represent around 5% of all cerebrovascular malformations. They can be single or multiple, and sporadic or familial. The presence of multiple lesions is more frequent in familial cavernomatosis. Ten to 30 % are associated with familial clustering. Case report. We presented the case of a 43-year-old man, admitted to the Emergency Department due to unprovoked seizure during the wide awake and everyday activities. Neurological examination was with no focal signs. A 32-channel standard digital EEG was without any significant changes of normal baseline activity. After sleep deprivation EEG showed multifocal, bilateral and asymmetric polyspikes and sharpwaves activity. Hyperventilation induced generalized epileptiform discharges. MRI scan demonstrated multiple small cavernous angiomas. Neuropsychological testing demonstrated a delayed memory impairment. Neurosurgery treatment was not recommended, and the therapy with valproate 1 250 mg/day had an excellent efficacy with no singnificant adverse effects. Conclusion. This patient considered as a rare case with multiple cavernomatosis highlights the importance of neuroradiological examination in adult patients with the first epileptic seizure but with no focal neurological signs. .

  7. Radiation risk due to occupational exposure

    International Nuclear Information System (INIS)

    Kargbo, A.A

    2012-04-01

    Exposure to ionizing radiation occurs in many occupations. Workers can be exposed to both natural and artificial sources of radiation. Any exposure to ionizing radiation incurs some risk, either to the individual or to the individual's progeny. This dissertation investigated the radiation risk due to occupational exposure in industrial radiography. Analysis of the reported risk estimates to occupational exposure contained in the UNSCEAR report of 2008 in industrial radiography practice was done. The causes of accidents in industrial radiography include: Lack of or inadequate regulatory control, inadequate training, failure to follow operational procedures, human error, equipment malfunction or defect, inadequate maintenance and wilful violation have been identified as primary causes of accidents. To minimise radiation risks in industrial radiography exposure devices and facilities should be designed such that there is intrinsic safety and operational safety ensured by establishing a quality assurance programme, safety culture fostered and maintained among all workers, industrial radiography is performed in compliance with approved local rules, workers engaged have appropriate qualifications and training, available safe operational procedures are followed, a means is provided for detecting incidents and accidents and an analysis of the causes and lessons learned. (author)

  8. Sepsis due to clostridium septicum: case report

    International Nuclear Information System (INIS)

    Foga, M.M.; McGinn, G.J.; Kroeker, M.A.; Guzman, R.

    2000-01-01

    Clostridium septicum is an unusual anaerobic, gram-positive, gas-producing bacillus, which has been identified as a cause of fulminant rapidly fatal infection in humans. Infection with C. septicum usually occurs in patients with cancer, patients receiving immunosuppressive chemotherapy, or patients with a nonmalignant hematological disorder such as hemolytic uremic syndrome. C. septicum infection most commonly involves the abdomen, and a recent review article has identified 164 cases in the medical literature describing the abdominal findings in this disease. Intracranial manifestation of C. septicum infection are less common and include meningitis, cerebritis, abscess formation and pneumocephalus. There have been only 12 documented cases in the English literature describing central nervous system lesions associated with C. septicum. We present a case report of a 56-year-old man in whom septicemia due to C. septicum developed as a complication of Crohn's disease. To our knowledge, there has never been a previous report of C. septicum sepsis related to underlying Crohn's disease. Our case is also remarkable in that an intracerebral gas collection developed at the site of a mycotic infarct related to C. septicum bacteremia, Intracranial, intraparenchymal gas formation related to anaerobic infection is extremely rare; to our knowledge, this radiological finding related to C. septicum sepsis has been described in only 1 previous case report in the medical literature. We also describe the intra-abdominal manifestations of C. septicum sepsis that occurred in this patient as well as the associated radiographic and pathologic findings. (author)

  9. Changes in Fracture Compliance Due to Roughness

    Science.gov (United States)

    Ahmadi, M.; Dahi Taleghani, A.; Sayers, C. M.

    2014-12-01

    Rock fractures are a source of extra compliance, and the effect of fractures on seismic wave propagation can be quantified in terms of the normal and shear fracture compliances. However, fractures are usually assumed to be smooth discontinuities with no preferential orientation for slippage. This assumption rarely matches with outcrop studies. Irregularities always exist on the fracture faces in the form of hackles, slickensides, or gouges. These features may facilitate movement in one direction while oppose shear deformation in the other direction due to the saw-tooth structure of irregularities. This direction dependence of the shear compliance of the fracture planes may affect the measured ratio of normal to shear fracture compliance for different locations along the fracture. Furthermore, these effects may contribute to the pressure dependence of fracture compliance, because fracture opening or shear sliding would change the number of asperities in contact and, consequently, affect the ratio of the normal to shear compliance. Here, we use numerical modeling to investigate the change in normal and shear compliance caused by the presence of slickensides. The effect of the hackles' geometry, the friction coefficient between the fracture surfaces, and the offset between the fracture faces will be discussed in this presentation. Our analysis shows that even in the case of low asperity angles or small offsets between the fracture faces, the fracture compliance ratio could be greater than one, in agreement with several field observations available in the literature.

  10. Hospitalisations due to falls in older persons.

    LENUS (Irish Health Repository)

    Carey, D

    2005-06-01

    This paper describes hospitalisations due to falls among people aged 65 years and over resident in the Eastern Region of Ireland. Of the 2,029 hospitalisations recorded for 2002, 78% were female and 68% were aged 75 years and over. Fractures accounted for 1,697 or 84% of cases with nearly half of them (841) sustained to the hip. Females were more likely to have a limb fracture whereas males were more likely to have a head injury. The total inpatient costs of the 2,029 hospitalisations were estimated at 10.6 million euros. Hip fractures were the costliest injuries as they accounted for 7.4 million euros (70%) of inpatient costs. There are also substantial additional costs implications for hip fractures as they constituted the majority (56%) of cases transferred to nursing\\/convalescent homes or long-stay health facilities. In keeping with an ageing population, the problem of injuries in older people is likely to increase over time and as falls are the dominant cause of those injuries, all acute and long-stay health facilities need to develop and implement fall prevention strategies for older people.

  11. Verifying the gravitational shift due to the earth's rotation

    International Nuclear Information System (INIS)

    Briatore, L.; Leschiutta, S.

    1976-01-01

    Data on various independent time scales kept in different laboratories are elaborated in order to verify the gravitational shift due to the earth's rotation. It is shown that the state of the art in the measurement of time is just now resulting in the possibility to make measurement of Δ t/t approximately 10 -13 . Moreover it is shown an experimental evidence of the earth's rotation relativistic effects

  12. Particle resuspension due to human walking

    International Nuclear Information System (INIS)

    Mana, Zakaria

    2014-01-01

    In nuclear facilities, during normal operations in controlled areas, workers could be exposed to radioactive aerosols (1 μm ≤ dp ≤ 10 μm). One of the airborne contamination sources is particles that are initially seeded on the floor and could be removed by workers while they are walking. During the outage of EDF nuclear facilities, there is a resuspension of some radionuclides in aerosol form (1 μm ≤ dp ≤ 10 μm). Since the number of co-activity will increase in reactors buildings of EDF, it becomes important to understand particle resuspension due to the activity of the operators to reduce their radiation exposure. The purpose of this Ph.D thesis is to quantify the resuspension of particles due to the progress of operators on a contaminated soil. Thus, the approach is to combine an aerodynamic resuspension model with numerical calculations of flow under a shoe, and then to characterize experimentally some input parameters of the model (particle diameter, adhesion forces, shoes motion). The resuspension model Rock'n'Roll proposed by Reeks and Hall (2001) was chosen because it describes physically the resuspension mechanism and because it is based on the moment of forces applied to a particle. This model requires two input parameters such as friction velocity and adhesion forces distribution applied on each particle. Regarding the first argument, numerical simulations were carried on using the ANSYS CFX software applied to a safety shoe in motion (digitized by 3D CAO); the mapping of friction velocity shows values of about 1 m.s -1 for an angular average velocity of 200 degrees.s -1 . As regards the second parameter, AFM (Atomic Force Microscopy) measurements were carried out with alumina and cobalt oxide particles in contact with epoxy surfaces representative of those encountered in EDF power plants. AFM provides the distribution of adhesion forces and reveals a much lower value than what can be calculated theoretically using JKR model (Johnson

  13. Caregiver anxiety due to interstage feeding concerns.

    Science.gov (United States)

    Stewart, Jamie; Dempster, Robert; Allen, Robin; Miller-Tate, Holly; Dickson, Gabrielle; Fichtner, Samantha; Principe, Alex J; Fonseca, Rachel; Nicholson, Lisa; Cua, Clifford L

    2015-01-01

    Improved weight gain during the interstage (IS) period has been shown to improve overall outcomes in patients with single ventricle physiology (SVP). This emphasis on nutrition may have untoward effects, such as increasing anxiety/stress levels in caregivers, who are already known to be at risk for increased anxiety/stress levels. The goal of this study was to evaluate anxiety/stress levels of caregivers as it pertains to feeding during the IS period and to determine if certain characteristics were associated with higher anxiety/stress scores. Caregivers of children with SVP who completed the IS period, defined as the time between the first and second cardiac surgeries, were recruited. Baseline demographics were obtained. Anxiety/stress levels were measured via eight questions using a 0- to 10-point scale. Correlations were performed between demographic variables and anxiety/stress level scores. Fifty-six surveys were completed (39 males, 27 females) on 43 children. Fourteen children required tube feeds during the IS period. There were significant correlations between anxiety/stress scores and caregiver's gender, caregiver's age, caregiver's level of education, percent of time a caregiver spent feeding the child, if caregivers were taking medications for anxiety, and if the child was seen in the emergency room during the IS period. There were no correlation of anxiety/stress scores with caregiver's race, child's underlying cardiac diagnosis, age of child, route of feeding during the IS period, birth order of the child or number of children in the family, relationship status, or distance from the hospital. In general, caregivers of children with SVP experience anxiety/stress during the IS period specifically due to feeding concerns. Certain intrinsic and extrinsic characteristics were associated with higher anxiety/stress levels. Future studies are needed to determine how to minimize anxiety/stress levels during this stressful time period. © 2015 Wiley Periodicals

  14. [Asthma and allergy due to carmine dye].

    Science.gov (United States)

    Tabar, A I; Acero, S; Arregui, C; Urdánoz, M; Quirce, S

    2003-01-01

    Cochineal carmine, or simply carmine (E120), is a red colouring that is obtained from the dried bodies of the female insect Dactylopius coccus Costa (the cochineal insect). We have evaluated the prevalence of sensitization and asthma caused by carmine in a factory using natural colouring, following the diagnosis of two workers with occupational asthma. The accumulated incidence of sensitization and occupational asthma due to carmine in this factory are 48.1% and 18.5% respectively, figures that make the introduction of preventive measures obligatory. Occupational asthma caused by inhaling carmine should be considered as a further example of the capacity of certain protein particles of arthropods (in this case cochineal insects) to act as aeroallergens. Carmine should be added to the list of agents capable of producing occupational asthma, whose mechanism, according to our studies, would be immunological mediated by IgE antibodies in the face of diverse allergens of high molecular weight, which can vary from patient to patient. Nonetheless, given the existence of different components in carmine, it cannot be ruled out that substances of low molecular weight, such as carminic acid, might act as haptenes. Besides, since we are dealing with a colouring that is widely used as a food additive, as a pharmaceutical excipient and in the composition of numerous cosmetics, it is not surprising that allergic reactions can appear both through ingestion and through direct cutaneous contact. We find ourselves facing a new example of an allergen that can act through both inhalation and digestion, giving rise to an allergolical syndrome that can show itself clinically with expressions of both respiratory allergy and alimentary allergy.

  15. Imaging of chest disease due to intravenous heroin abuse

    International Nuclear Information System (INIS)

    Lian Xuhui; Chen Zhong; Ye Wenqin

    2002-01-01

    Objective: To study the imaging findings of the chest disease due to intravenous heroin abuse. Methods: Twenty-five cases of clinically confirmed chest disease due to intravenous heroin abuse were retrospectively analyzed. 25 cases had conventional X-ray film, 6 cases had CT scanning, and 6 cases had echocardiography scanning. Results: On X-ray and CT, the following signs were found: lung making manifold (n = 5), small patchy shadow (n = 15), pneumatocele (n = 16), small cavity (n = 16), small node (n = 7), pleural effusion (n = 8 ), pneumothorax (n = 2), hydropneumothorax (n = 6), pulmonary edema (n = 2), megacardia (n = 11), multiple-shaped lesion (n = 20). On echocardiography, tricuspid vegetation (n = 4) and tricuspid insufficiency (n = 4) were found. Conclusion: The X-ray and CT manifestations of chest inflammation due to intravenous heroin abuse are multiple. The multiple small cavities and pneumatoceles sign are of some value in the diagnosis of lung inflammation due to intravenous heroin abuse among young patients

  16. Radiation exposure due to agricultural uses of phosphate fertilizers

    International Nuclear Information System (INIS)

    Khater, Ashraf E.M.; AL-Sewaidan, H.A.

    2008-01-01

    Radiological impacts of phosphate rocks mining and manufacture could be significant due to the elevated radioactivity contents of the naturally occurring radioactive materials (NORM), such as 238 U series, 232 Th series and 40 K, in some phosphate deposits. Over the last decades, the land reclamation and agriculture activities in Saudi Arabia and other countries have been widely expanded. Therefore, the usage of chemical fertilizers is increased. Selected phosphate fertilizers samples were collected and the specific activities of NORM were measured using a gamma ray spectrometer based on a hyper pure germanium detector and alpha spectrometer based on surface barrier detector. The obtained results show remarkable wide variations in the radioactivity contents of the different phosphate fertilizer samples. The mean (ranges) of specific activities for 226 Ra, 210 Po, 232 Th and 40 K, and radium equivalent activity are 75 (3-283), 25 (0.5-110), 23 (2-74), 2818 (9-6501) Bq/kg and 283 (7-589) Bq/kg, respectively. Based on dose calculations, the increment of the public radiation exposure due to the regular agricultural usage of phosphate fertilizers is negligible. Its average value 1 m above the ground is about 0.12 nGy/h where the world average value due to the NORM in soil is 51 nGy/h. Direct radiation exposures of the farmers due to phosphate fertilizers application was not considered in our study

  17. Transverse correlation vanishing due to phase aberrations

    CSIR Research Space (South Africa)

    Godin, T

    2011-06-01

    Full Text Available ) (Holoeye, PLUTO-VIS) with 1920x1080 pixels of pitch 8?m and calibrated for a pi2 phase shift at 633nm. The incident beam radius on the SLM was W=1.5 mm and its angle of incidence was kept as small as possible (<15?). A diaphragm (D1 ) was set after... this discrepancy, let us examine the influence of the clipping that should result from the diaphragm D1 set after the SLM (Fig. 9). The resulting diffraction can be characterised by the truncation ratio WY DD /1?= , where 1D? is the radius of diaphragm D1...

  18. Damping in accelerators due to classical radiation

    International Nuclear Information System (INIS)

    Mills, F.E.

    1962-01-01

    The rates of change of the magnitudes of the adiabatic invariants is calculated in the case of a Hamiltonian system subjected to generalized non conservative forces. These results are applied to the case of the classical radiation of electrons in an accelerator or storage ring. The resulting expressions for the damping rates of three independent oscillation modes suggest structures which are damping in all three modes, while at the same time allowing 'strong focussing' and the attendant strong momentum compaction. (author)

  19. Park power deficit due to atmospheric stability

    DEFF Research Database (Denmark)

    Hansen, Kurt Schaldemose; Barthelmie, Rebecca; Ott, Søren

    The purpose of this paper is to present a power deficit analysis based on offshore wind farm measurements with respect to the atmospheric stability classification. The result is used to validate wind farm prediction models under different inflow and atmospheric stability conditions......The purpose of this paper is to present a power deficit analysis based on offshore wind farm measurements with respect to the atmospheric stability classification. The result is used to validate wind farm prediction models under different inflow and atmospheric stability conditions...

  20. The differential effects of fluency due to repetition and fluency due to color contrast on judgments of truth.

    Science.gov (United States)

    Silva, Rita R; Garcia-Marques, Teresa; Mello, Joana

    2016-09-01

    Two experiments contrast the effects of fluency due to repetition and fluency due to color contrast on judgments of truth, after participants learn to associate high levels of fluency with falseness (i.e., a reversal of the fluency-truth link). Experiment 1 shows that the interpretation of fluency as a sign of truth is harder to reverse when learning is promoted with repetition rather than with perceptual fluency. Experiment 2 shows that when color contrast and repetition are manipulated orthogonally, the reversal of the truth effect learned with color contrast does not generalize to repetition. These results suggest specificities in the processing experiences generated by different sources of fluency, and that their influences can be separated in contexts that allow the contrast of their distinctive features. We interpret and discuss these results in light of the research addressing the convergence vs. dissociation of the effects elicited by different fluency sources.

  1. NUMERICAL SOLUTIONS OF SOME PARAMETRIC EFFECTS DUE ...

    African Journals Online (AJOL)

    Dr A.B.Ahmed

    ABSTRACT. The analytical solutions for the scattering of electromagnetic waves from an infinite circular cylinder and refractive index are programmed in FORTRAN (Barber and Hill, 1990). The resulting quantities include the scattering coefficients, the scattering amplitudes and the intensities. The range of variable input.

  2. [Mid-term outcome after fusion due to isthmic spondylolysis].

    Science.gov (United States)

    Ivanic, Gerd M; Pink, Peter T; Ziegler, Sven; Harter, Bernd; Schneider, Frank; Plattner, Florian; Homann, Nikolaus C

    2007-01-01

    The isthmic spondylolisthesis, as a result of a spondylolysis, has an incidence of about 5%. It plays a major role in the cause of low back pain. If conservative treatment fails, surgery is indicated. The study examined the working disability after fusion operations due to isthmic spondylolisthesis. The results are very promising, as 2/3 of the patients could go back to the same work. 87% of the patients showed a good or very good outcome. This operation should thus be recommended if conservative treatment fails.

  3. Deforestation due to Urbanization: a Case Study for Trabzon, Turkey

    Science.gov (United States)

    Telkenaroglu, C.; Dikmen, M.

    2017-11-01

    This paper inspects the deforestation of Trabzon in Turkey, due to urbanization, between 2006 and 2016. For this purpose, Landsat 7 ETM+ (Enhanced Thematic Mapper Plus) images are obtained from United States Geographical Survey (USGS) archive (USGS, 2017a) and their VNIR bands related to this study are utilized. For both years, and for each band, histograms are equalized. Finally, Normalized Difference Vegetation Index (NDVI) values are calculated as images. Resulting vegetation indexes are assessed in comparison to the binary ground truth images. A visual inspection is also done with respect to Google's Timelapse images for each year to validate and support the results.

  4. Artificial noise due to DC electric trains

    International Nuclear Information System (INIS)

    Senanayake, W.E.

    1987-08-01

    The current distribution in a DC railway and the resulting magnetic effects have been modelled using the parameters of the DC railway networks in Italy. The results show that the magnetic perturbations are substantially high in the vicinity of electrified railway lines. The order of magnitude of the induced field can be as significant as ∼ 40nT at a distance of ≅ 2km from the railway line indicating that geophysical techniques that employ natural magnetic anomalies can be badly effected, within this range. The magnetic effects rapidly decay with increasing distance, but the noise level could be significant even at a range of ∼ 10km. Also, these induced anomalies vary significantly with the conductivity of the ground. When the conductivity is high it is possible that the railway currents dispersed through the ground interact with those induced in the earth, causing a severe disruption to the telluric measurements. (author). 11 refs, 10 figs, 1 tab

  5. Spontaneous pneumomediastinum due to paralytic rabies

    Directory of Open Access Journals (Sweden)

    Wuping Wang

    2013-02-01

    Full Text Available Rabies is a fatal disease resulting from rabies virus infection, causing severe neurological symptoms and ultimately death by destroying the nervous system. In general, a patient tends to see a neurologist or an infectious diseases physician, with very common and typical discipline-related signs and symptoms, such as hydrophobia, aerophobia, and mental disorders. However, we reported a rabies patient who was first admitted to see a thoracic surgeon with spontaneous pneumomediastinum.

  6. Spontaneous pneumomediastinum due to paralytic rabies

    Directory of Open Access Journals (Sweden)

    Wuping Wang

    Full Text Available Rabies is a fatal disease resulting from rabies virus infection, causing severe neurological symptoms and ultimately death by destroying the nervous system. In general, a patient tends to see a neurologist or an infectious diseases physician, with very common and typical discipline-related signs and symptoms, such as hydrophobia, aerophobia, and mental disorders. However, we reported a rabies patient who was first admitted to see a thoracic surgeon with spontaneous pneumomediastinum.

  7. Uranium contamination due to nuclear power plants

    Energy Technology Data Exchange (ETDEWEB)

    Martin Sanchez, A.; Vera Tome, F.; Diaz Bejarano, J.; Garcia Aparicio, A. (Univ. de Extremadura, Badajoz (Spain). Dept. de Fisica)

    1992-01-01

    Measurements of uranium isotopes and their daughters in the natural series were performed in the cooling reservoirs and their neighborhood of two nuclear power plants, [alpha] and [gamma] spectrometry of samples were used to measure the natural and artificial radionuclides. The nuclear power plants are in the southwest of Spain and one of them has been in operation since 1982, the other plant is in the construction phase. We compare the results obtained for the two sites. (orig.).

  8. Cosmogenic activation: Recent results

    Science.gov (United States)

    Kudryavtsev, Vitaly A.

    2018-01-01

    Activation of materials is known to cause background events in underground experiments that may affect the sensitivity of these experiments to rare event searches. The most common source of activation is the exposure of materials to cosmic rays at the surface of the Earth but other various sources of neutrons may also be dangerous. Different computer codes provide estimates of production rates of radioactive isotopes due to activation but their results are sometimes inconsistent. High-sensitivity experiments looking for dark matter, neutrino-less double-beta decay or neutrinos from various sources, although affected by activation, provide crucial tests of models used in the codes. Recent calculations and measurements of activation rates are discussed in this paper.

  9. Heat Loss Due To Thermal Bridges In Buildings

    Science.gov (United States)

    Fang, J. B.; tarot, R. A.; Childs, K. W.; Courville, G. E.

    1984-03-01

    Building envelopes often contain numerous highly conductive heat flow paths, called thermal bridges, which are major sources of heat loss and deterioration of building materials due to moisture condensation. Some examples of thermal bridges occurring in office buildings are presented. Infrared thermography was used to identify the locations and magnitudes of thermally defective areas resulting from inadequate construction, design, or substandard workmanship in existing buildings. Due to the large thermal inertia of building components and transient conditions caused by fluctuating outdoor and indoor temperatures, long measurement periods are required. This makes thermography impractical for quantifying the heat loss. In order to estimate the heat loss rate from thermal bridges and to obtain a better understanding of the physical processes involved, a two-dimensional heat flow model has been developed for transient heat conduction within the exterior wall/intermediate floor systems. The calculated results from the mathematical model are compared with available experimental data. An in-situ measurement technique, which is currently under development at NBS for quantifying the energy loss due to thermal bridges, is described.

  10. Thermal Embrittlement of Reactor Pressure Vessel Steel due to Aging

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Soo; Park, Duck Gun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    Thermal SS sets are located above the nuclear core where a fast neutron flux is negligible and temperature is 320 .deg. C (as opposed to 290 .deg. C in locations of high-irradiated SS). These SS allow monitoring of continuous operation temperature exposure effect on mechanical characteristics of the steels. Although transgranular cleavage is the predominant mode of brittle fracture in RPV steels, solute (e.g. phosphorus) segregation to grain boundaries can result in another type of brittle fracture known as intergranular (grain boundary) fracture. Figures 1 a) and b) show examples of transgranular and intergranular (IG) fracture, respectively, as viewed in a scanning electron microscope. The investigators have interpreted the intergranular cracking occurs as a result of segregation of sulfur and/or phosphorus at grain boundary. The IG cracking is a kind of symptom of embrittlement. It is reported that the IG cracking occurs in inert (Ar) environment under slow strain rate test. 1. The lath grain size in SA508 RPV steel increases slightly due to thermal aging at 350, 420, and 420 .deg. C for 2,250H. 2. The decrease in toughness appeared 4-25% and the lattice contraction appeared to be +0.004% - -0.022% due to thermal aging at 350, 420, and 420 .deg. C for 2,250H. 3. The amount of decrease in Charpy impact energy due to thermal aging is correlated well with the magnitude of lattice contraction.

  11. [Percutaneous surgery for plantar fasciitis due to a calcaneal spur].

    Science.gov (United States)

    Apóstol-González, Saúl; Herrera, Jesús

    2009-01-01

    Determine the efficacy of percutaneous surgical treatment for talalgia due to a calcaneal spur. This is an observational, descriptive, clinical series analyzing the outcomes of 10 patients with a diagnosis of talalgia due to plantar fasciitis with a calcaneal spur treated with percutaneous foot surgery. The end result was assessed with a visual analog scale (VAS) to measure pain, the patients' opinion and their return to activities of daily living. Central tendency and scatter measurements were calculated. The inferential analysis was done with the non-parametric chi square (chi2) test. Most patients were females (90%) and mean age was 40.5 years. Follow-up was 12 months. One patient had bleeding of the approached area. Pain was reduced from 8 to 1.5 in the VAS. Nine patients returned to their activities. Two patients had occasional mild pain upon prolonged bipedestation. Ninety percent of results were satisfactory. Percutaneous foot surgery in talalgias caused by plantar fasciitis due to a calcaneal spur is a simple and effective method. It reduces the operative time and allows for an early return of patients to their activities of daily living.

  12. SIMULATION OF SCOURING AROUND A VERTICAL CYLINDER DUE TO TSUNAMI

    Directory of Open Access Journals (Sweden)

    Kuswandi

    2017-06-01

    Full Text Available Local scour due to tsunami is damaging especially on shallow foundation. Although relatively in a short duration, tsunami attack may scour material around buildings that led to destruction. A number of formulae on local scouring due to flood and tsunami have been available. The local scouring pattern and depth produced by tsunami may be affected by tsunami duration and tsunami surge Froude number and hence different to that resulted by flood which normally have much longer duration and lower Froude number. The research used a relatively short flume to create short duration tsunami surge that run-up on 1:20 beach slope and hit a vertical cylinder on land. Both the pattern and the depth of local scouring around the cylinder were observed and the results were compared with similar research but with different tsunami surge characteristic. It was shown that the maximum scour depth was significantly deeper than the final scour depth. When compared with other experimental study of local scour due to tsunami, the present local scour maximum depth seemed to be slightly less. This could have been caused by the relatively short duration of the present experiment. It was also found that the sidewall effect was insignificant when the ratio of cylinder diameter to the flume width was less then approximately 0.15.

  13. The role of phonophoresis in dyshpagia due to cervical osteophytes

    Directory of Open Access Journals (Sweden)

    Zeliha Unlu

    2008-08-01

    Full Text Available Zeliha Unlu1, Sebnem Orguc2, Gorkem Eskiizmir3, Asim Aslan3, Saliha Tasci11Department of Physical Medicine and Rehabilitation; 2Department of Radiology; 3Department of Otorhinolaryngology, Celal Bayar University School of Medicine, Manisa, TurkeyObjective: Treatment of patients with anterior cervical osteophytes causing dysphagia includes conservative treatment with anti-inflammatory drugs, muscle relaxants, antibiotics, and an appropriate soft diet. Physical therapy with its advantages may be an alternative method in the treatment, which was not reported previously.Case description: Phonophoresis therapy is applied in nine patients with dysphagia due to cervical osteophytes.Results: The symptom of dysphagia regressed in various degrees in all patients after phonophoresis therapy.Conclusions: Phonophoresis might be an alternative method for the non-steroidal anti-inflammatory drug (NSAID treatment in patients with dysphagia due to cervical osteophytes.Keywords: cervical, osteophyte, dysphagia, physical therapy

  14. MRI evaluation of pituitary hyperplasia due to primary hypothyroidism

    International Nuclear Information System (INIS)

    Jiang Chunjing; Shu Jin'er; Li Huimin; Sheng Sanlan; Lu Jinhua

    2010-01-01

    Objective: To analyze the MRI manifestations of the pituitary hyperplasia due to primary hypothyroidism and to improve the differential diagnosis of secondary pituitary hyperplasia and pituitary tumors. Methods: The MRI findings of pituitary hyperplasia in 10 documented primary hypothyroidism patients (male 3, female 7; age range: 9-15 years) were reviewed. The pulse sequences using a 1.0T MR scanner included coronal and sagittal T 1 W, coronal T 2 W and coronal contrast-enhanced T 1 W in all patients. Results: The pituitary gland was markedly enlarged with mean height of 15.5 mm (11-23 mm). Central bulging of pituitary gland was seen in all 10 patients with mild displacement of the infundibulum in 3 and sellar enlargement in 5. All glands had homogeneous MR signal intensities and contrast enhancement. Conclusion: Pituitary hyperplasia due to primary hypothyroidism has characteristic MR features of central bulging with homogeneous signal intensities and contrast enhancement. (authors)

  15. Gastric Outlet Obstruction due to Gastrointestinal Amyloidosis.

    Science.gov (United States)

    Cohen, Jared A; An, Jong; Brown, Alexander W; Spearman, Darren; Paredes, Angelo

    2017-03-01

    A 64- year-old man with smoldering myeloma presented to the hospital for nausea, vomiting, and PO intolerance. Abdominal CT demonstrated massive gastric distention and collapsed proximal duodenum consistent with gastric outlet obstruction (GOO). Esophagogastroduodenoscopy demonstrated pyloric edema. Duodenal biopsies were consistent with AL amyloidosis. Given the concerns for bleeding risk and immediate need to start chemotherapy, surgery was deferred. Chemotherapy was initiated with a good clinical response. Our non-operative approach is novel, eliminates perioperative adverse events, allows for early initiation of chemotherapy, and can serve as a model for patients with GOO resulting from AL amyloidosis who are not surgical candidates.

  16. Extreme situations due to gender violence

    Directory of Open Access Journals (Sweden)

    Stela Meneghel

    2012-11-01

    Full Text Available This paper presents a synthesis of the third Critical Paths Seminar, held in Porto Alegre/Brazil in 2011, whose focus was extreme situations of gender violence. The extreme situations are human rights violations that include femicide or murder motivated by the situation of gender; LGBT murders, human rights violations of ethnic and racial minorities, sexual exploitation, violence to women in vulnerable situations and other violence caused by gender. The meeting objective was given space to share experiences, reflect critically and build strategies for facing violence and extreme situations resulting from gender systems.

  17. Accidents due to falls from roof slabs.

    Science.gov (United States)

    Rudelli, Bruno Alves; Silva, Marcelo Valerio Alabarce da; Akkari, Miguel; Santili, Claudio

    2013-01-01

    CONTEXT AND OBJECTIVE Falls from the roof slabs of houses are accidents of high potential severity that occur in large Brazilian cities and often affect children and adolescents. The aims of this study were to characterize the factors that predispose towards this type of fall involving children and adolescents, quantify the severity of associated lesions and suggest preventive measures. DESIGN AND SETTING Descriptive observational prospective longitudinal study in two hospitals in the metropolitan region of São Paulo. METHODS Data were collected from 29 cases of falls from roof slabs involving children and adolescents between October 2008 and October 2009. RESULTS Cases involving males were more prevalent, accounting for 84%. The predominant age group was schoolchildren (7 to 12 years old; 44%). Leisure activities were most frequently being practiced on the roof slab at the time of the fall (86%), and flying a kite was the most prevalent game (37.9%). In 72% of the cases, the children were unaccompanied by an adult responsible for them. Severe conditions such as multiple trauma and traumatic brain injuries resulted from 79% of the accidents. CONCLUSION Falls from roof slabs are accidents of high potential severity, and preventive measures aimed towards informing parents and guardians about the dangers and risk factors associated with this type of accident are needed, along with physical protective measures, such as low walls around the slab and gates with locks to restrict free access to these places.

  18. Accidents due to falls from roof slabs

    Directory of Open Access Journals (Sweden)

    Bruno Alves Rudelli

    Full Text Available CONTEXT AND OBJECTIVE Falls from the roof slabs of houses are accidents of high potential severity that occur in large Brazilian cities and often affect children and adolescents. The aims of this study were to characterize the factors that predispose towards this type of fall involving children and adolescents, quantify the severity of associated lesions and suggest preventive measures. DESIGN AND SETTING Descriptive observational prospective longitudinal study in two hospitals in the metropolitan region of São Paulo. METHODS Data were collected from 29 cases of falls from roof slabs involving children and adolescents between October 2008 and October 2009. RESULTS Cases involving males were more prevalent, accounting for 84%. The predominant age group was schoolchildren (7 to 12 years old; 44%. Leisure activities were most frequently being practiced on the roof slab at the time of the fall (86%, and flying a kite was the most prevalent game (37.9%. In 72% of the cases, the children were unaccompanied by an adult responsible for them. Severe conditions such as multiple trauma and traumatic brain injuries resulted from 79% of the accidents. CONCLUSION Falls from roof slabs are accidents of high potential severity, and preventive measures aimed towards informing parents and guardians about the dangers and risk factors associated with this type of accident are needed, along with physical protective measures, such as low walls around the slab and gates with locks to restrict free access to these places.

  19. Cholesterol testing and results

    Science.gov (United States)

    Cholesterol test results; LDL test results; VLDL test results; HDL test results; Coronary risk profile results; Hyperlipidemia-results; Lipid disorder test results; Heart disease - cholesterol results

  20. [Problematic breastfeeding due to a short frenulum].

    Science.gov (United States)

    Post, Erica D M; Rupert, A W M Stijn; Schulpen, Tom W J

    2010-01-01

    Ankyloglossia (tongue tie) in the neonate can be a cause of breastfeeding problems. Frenotomy (cutting of the frenulum linguae) had fallen into disrepute, but has regained its place as a standard medical procedure in Anglo-Saxon countries, though not in the Netherlands. We present two neonates, both boys, presenting with breastfeeding problems caused by ankyloglossia. The first baby described did not drink enough and hence did not gain any weight. The mother of the second patient experienced a great deal of pain and had cracked nipples, caused by an abnormal suckling action. Both boys underwent frenotomy with good result. Recent ultrasound studies reveal that frenotomy immediately normalizes the suckling action in babies with ankyloglossia. Randomized controlled trials show that 95% of breastfeeding problems disappear. There is sufficient evidence to state that frenotomy is a very safe and useful procedure in neonates.

  1. Magma ocean formation due to giant impacts

    Science.gov (United States)

    Tonks, W. B.; Melosh, H. J.

    1993-01-01

    The thermal effects of giant impacts are studied by estimating the melt volume generated by the initial shock wave and corresponding magma ocean depths. Additionally, the effects of the planet's initial temperature on the generated melt volume are examined. The shock pressure required to completely melt the material is determined using the Hugoniot curve plotted in pressure-entropy space. Once the melting pressure is known, an impact melting model is used to estimate the radial distance melting occurred from the impact site. The melt region's geometry then determines the associated melt volume. The model is also used to estimate the partial melt volume. Magma ocean depths resulting from both excavated and retained melt are calculated, and the melt fraction not excavated during the formation of the crater is estimated. The fraction of a planet melted by the initial shock wave is also estimated using the model.

  2. Estimating mortality due to cigarette smoking

    DEFF Research Database (Denmark)

    Brønnum-Hansen, Henrik; Juel, K

    2000-01-01

    We estimated the mortality from various diseases caused by cigarette smoking using two methods and compared the results. In one method, the "Prevent" model is used to simulate the effect on mortality of the prevalence of cigarette smoking derived retrospectively. The other method, suggested by R...... are small and appear to be explicable. The Prevent model can be used for more general scenarios of effective health promotion, but it requires more data than the Peto et al method, which can be used only to estimate mortality related to smoking........ Peto et al (Lancet 1992;339:1268-1278), requires data on mortality from lung cancer among people who have never smoked and among smokers, but it does not require data on the prevalence of smoking. In the Prevent model, 33% of deaths among men and 23% of those among women in 1993 from lung cancer...

  3. Underestimation of risk due to exposure misclassification

    DEFF Research Database (Denmark)

    Grandjean, Philippe; Budtz-Jørgensen, Esben; Keiding, Niels

    2004-01-01

    Exposure misclassification constitutes a major obstacle when developing dose-response relationships for risk assessment. A non-differentional error results in underestimation of the risk. If the degree of misclassification is known, adjustment may be achieved by sensitivity analysis. The purpose...... of this study was to examine the full magnitude of measurement error in determining the prenatal exposure to methylmercury. We used data from a prospective study of a Faroese birth cohort. Two biomarkers of methylmercury exposure were available, i.e., the mercury concentrations in cord blood and in maternal....... These findings illustrate that measurement error may be greatly underestimated if judged solely from reproducibility or laboratory quality data. Adjustment by sensitivity analysis is meaningful only if realistic measurement errors are applied. When exposure measurement errors are overlooked or underestimated...

  4. Estimating mortality due to cigarette smoking

    DEFF Research Database (Denmark)

    Brønnum-Hansen, Henrik; Juel, K

    2000-01-01

    We estimated the mortality from various diseases caused by cigarette smoking using two methods and compared the results. In one method, the "Prevent" model is used to simulate the effect on mortality of the prevalence of cigarette smoking derived retrospectively. The other method, suggested by R....... Peto et al (Lancet 1992;339:1268-1278), requires data on mortality from lung cancer among people who have never smoked and among smokers, but it does not require data on the prevalence of smoking. In the Prevent model, 33% of deaths among men and 23% of those among women in 1993 from lung cancer......, chronic bronchitis, emphysema, ischemic heart disease, and stroke were caused by cigarette smoking. In the method proposed by Peto et al, 35% of deaths among men and 25% of deaths among women from these causes were estimated to be attributable to cigarette smoking. The differences between the two methods...

  5. Surface cooling due to forest fire smoke

    Science.gov (United States)

    Robock, Alan

    1991-11-01

    In four different cases of extensive forest fire smoke the surface temperature effects were determined under the smoke cloud. In all cases, daytime cooling and no nighttime effects were found. The locations of smoke clouds from extensive forest fires in western Canada in 1981 and 1982, in northern China and Siberia in 1987, and in Yellowstone National Park in northwestern Wyoming in 1988 were determined from satellite imagery. As these smoke clouds passed over the midwestern United States for the Canadian and Yellow-stone fires and over Alaska for the Chinese/Siberian fires, surface air temperature effects were determined by comparing actual surface air temperatures with those forecast by model output statistics (MOS) of the United States National Weather Service. MOS error fields corresponding to the smoke cloud locations showed day-time cooling of 1.5° to 7°C under the smoke but no nighttime effects. These results correspond to theoretical estimates of the effects of smoke, and they serve as observational confirmation of a portion of the nuclear winter theory. This also implies that smoke from biomass burning can have a daytime cooling effect of a few degrees over seasonal time scales. In order to properly simulate the present climate with a numerical climate model in regions of regular burning it may be necessary to include this smoke effect.

  6. Reinforced concrete behaviour due to missile impact

    International Nuclear Information System (INIS)

    Alderson, M.A.H.G.; Bartley, R.; O'Brien, T.P.

    1977-01-01

    The assessment of the safety of nuclear reactors has necessitated the study of the effect of missiles on reinforced concrete structures. A programme of experimental work has been initiated within the United Kingdom to resolve the problem of design for the shear stresses produced by the impact loading. The basic scale of the experiments has been chosen to be 1/25th and both hard and soft missiles have been employed. The missiles are launched by a compressed air gun towards a vertical, circular, reinforced concrete target, high speed cine photography and deflection gauges being employed to record the missile behaviour and response of the target. Hard missiles have initially been plane circular discs and soft missiles have been developed to simulate the scaled load/time characteristic of a MRCA impacting at a velocity of 215 m/s. Targets of different overall thickness and varying amounts of reinforcement have been tested. A theoretical analysis of the impact phenomena has also been carried out using computer programs based on finite difference methods (Dynamic Relaxation and PISCES 2DL). The paper outlines the experimental work performed and discusses the analytical assessment by comparison with the test results. (Auth.)

  7. PATHOGENESIS OF HEMORRHAGIC DUE TO DENGUE VIRUS

    Directory of Open Access Journals (Sweden)

    Arief Suseno

    2015-01-01

    Full Text Available Dengue is a viral disease that is mediated by a mosquito, which causes morbidity and mortality. Viruses can increase vascular permeability which can lead to hemorrhagic diathesis or disseminated intravascular coagulation (DIC known as dengue hemorrhagic fever (DHF. In Indonesia, dengue hemorrhagic fever (DHF are caused by dengue virus infection which was found to be endemic accompanied by an explosion of extraordinary events that appear at various specified period. The diagnosis of dengue is determined based on the criteria of the World Health Organization (WHO, 1999, which are sudden high fever accompanied by a marked tendency to hemorrhage positive tourniquet test, petechiae, ecchymosis, purpura, mucosal hemorrhagic, hematemesis or melena and thrombocytopenia. The problem that still exists today is the mechanism of thrombocytopenia in patients with varying degrees of dengue involving levels of vWF (von Willebrand factor and prostaglandin I2 (PGI2 can not be explained. The mechanism of hemorrhagic in dengue virus infections acquired as a result of thrombocytopenia, platelet disfunction decreased coagulation factors, vasculopathy with endothelial injury and disseminated intravascular coagulation (DIC.

  8. Fixed Drug Eruption due to Achiote Dye

    Science.gov (United States)

    Tattersall, Ian; Reddy, Bobby Y.

    2016-01-01

    Fixed drug eruption (FDE) is a localized type IV sensitivity reaction to a systemically introduced allergen. It usually occurs as a result of new medication, making identification and avoidance of the trigger medication straightforward; however, in a rare subset of cases no pharmacological source is identified. In such cases, the causative agent is often a food or food additive. In this report we describe a case of a FDE in a 12-year-old girl recently immigrated to the United States from Ecuador who had no medication exposure over the course of her illness. Through an exhaustive patient history and literature review, we were able to hypothesize that her presentation was caused by a dietary change of the natural achiote dye used in the preparation of yellow rice to a locally available commercial dye mix containing tartrazine, or Yellow 5, which has previously been implicated in both systemic hypersensitivity reactions and specifically in FDE. This report adds to the small body of available literature on non-pharmacological fixed hypersensitivity eruptions and illustrates an effective approach to the management of such a presentation when history is not immediately revealing. PMID:26933409

  9. Fixed Drug Eruption due to Achiote Dye

    Directory of Open Access Journals (Sweden)

    Ian Tattersall

    2016-01-01

    Full Text Available Fixed drug eruption (FDE is a localized type IV sensitivity reaction to a systemically introduced allergen. It usually occurs as a result of new medication, making identification and avoidance of the trigger medication straightforward; however, in a rare subset of cases no pharmacological source is identified. In such cases, the causative agent is often a food or food additive. In this report we describe a case of a FDE in a 12-year-old girl recently immigrated to the United States from Ecuador who had no medication exposure over the course of her illness. Through an exhaustive patient history and literature review, we were able to hypothesize that her presentation was caused by a dietary change of the natural achiote dye used in the preparation of yellow rice to a locally available commercial dye mix containing tartrazine, or Yellow 5, which has previously been implicated in both systemic hypersensitivity reactions and specifically in FDE. This report adds to the small body of available literature on non-pharmacological fixed hypersensitivity eruptions and illustrates an effective approach to the management of such a presentation when history is not immediately revealing.

  10. Athletic footwear: unsafe due to perceptual illusions.

    Science.gov (United States)

    Robbins, S E; Gouw, G J

    1991-02-01

    Modern athletic footwear provides remarkable plantar comfort when walking, running, or jumping. However, when injurious plantar loads elicit negligible perceived plantar discomfort, a perceptual illusion is created whereby perceived impact is lower than actual impact, which results in inadequate impact-moderating behavior and consequent injury. The objective of this study was to examine how plantar tactile (mechanical) events affect perceived plantar discomfort. Also, we evaluated the feasibility of a footwear safety standard we propose, which requires elimination of the above illusion. Twenty subjects gave numerical estimates of plantar discomfort produced by simulated locomotion (concurrent vertical (0.1-0.7 kg.cm-2) and horizontal (0.1-0.9 kg.cm-2) plantar loads), with the foot supported by either a smooth rigid surface or a rigid surface with 2 mm high rigid irregularities. Vertical or horizontal load alone evoked no discomfort (P greater than 0.05), whereas together, discomfort emanated from loads as low as 0.4 kg.cm-2. Irregularities heightened discomfort by a factor of 1.89. This suggests that the proposed safety standard is feasible, since compliance could be achieved simply by adding surface irregularities to insoles and by other changes that heighten localized plantar loads. However, until this standard is adhered to, it might be more appropriate to classify athletic footwear as "safety hazards" rather than "protective devices".

  11. Assessment of complications due to intratympanic injections

    Directory of Open Access Journals (Sweden)

    Yu-Chuan Liu

    2016-03-01

    Full Text Available Objective: The purpose of the study is to report and to analyze the complications following intratympanic injections (ITI of steroids. The occurrence rate of complications at different ITI sites, four quadrants of eardrum, was also compared. Methods: A retrospective clinical review in a medical center. Each patient received ITI twice in a week for 2–3 consecutive weeks as a salvage therapy for sudden sensorineural hearing loss. Post-injection complications, especially transient dizziness and vertigo, were recorded. Patients with acute or chronic vertigo episodes in 1 month were excluded. Results: A total of 59 patients with sudden sensorineural hearing loss and a total of 278 times of ITI were performed in 1 year. The post-injection complications included pain, tongue numbness, transient dizziness, vertigo, tinnitus, and a small persistent perforation. There was no significant difference in the occurrence of these complications between the injections sites on the 4 quadrants of the tympanic membrane. However, there was statistical significance in the post-injection vertiginous episode after IT injections to posterior-inferior quadrant (Q3 and posterior-superior quadrant (Q4 compared to anterior-superior quadrant (Q1 and anterior-inferior quadrant (Q2 (P = 0.0113. Conclusion: IT injection is recommended to be applied to the Q2 since the Q1 and Q4 injections are more likely to induce the adverse effect of tongue numbness, while the Q3 and Q4 areas are more likely to induce post-injection vertigo. Keywords: Intratympanic injection, Sudden deafness, Complications, Vertigo

  12. hospitalised due to exacerbation of the disease

    Directory of Open Access Journals (Sweden)

    Dominika Anna Szalewska

    2016-12-01

    Full Text Available Background . Coronary artery disease (CAD is a common cause of hospitalisation in cardiac wards, while chronic pancreatitis (CP is in gastroenterology wards. Both diseases are chronic and the clinical picture is dominated by pain. Objectives . The objective was to describe the psychological characteristics of patients hospitalised for the worsening of CAD and CP. Material and methods. The sample comprised 30 patients with CAD and 30 with CP. Participants completed personal questionnaires, the Eysenck Personality Questionnaire-Revised, STAI , Beck Depression Inventory and Scale A-Framingham. Results . Mild depression occurred in 20% of patients with CAD and 30% with CP. A severe degree of depression was found in 20% of patients with CAD and in 15% with CP while the highest levels of anxiety (9–10 sten were found in 30% of patients with CP and in 20% of patients with CAD . In relation to introversion-extraversion personality dimension, 74% of patients with CAD and 53% of patients with CP were classified as ambivert or introvert. In both groups, most patients had moderate emotional balance as follows: 47% patients with CAD and 43% with CP. Conclusions . Compared to patients with CAD , patients with CP presented more severe depression symptoms and anxiety. The subjects with high intensification of neurotic traits more often presented high levels of anxiety and depression wherein more than half of these patients had severe anxiety and depression. Patients with low physical activity had significantly higher levels of anxiety than patients who were active daily or several times per week.

  13. Magnetic fluctuations due to thermally excited Alfven waves

    International Nuclear Information System (INIS)

    Agim, Y.Z.; Prager, S.C.

    1990-01-01

    Magnetic fluctuations due to the thermally excited MHD waves are investigated using fluid and kinetic models to describe a stable, uniform, compressible plasma in the range above the drift wave frequency and below the ion cyclotron frequency. It is shown that the fluid model with resistivity yields spectral densities which are roughly Lorentzian, exhibit equipartition with no apparent cutoff in wavenumber space and a Bohm-type diffusion coefficient. Under certain conditions, the ensuing transport may be comparable to classical values. For a phenomenological cutoff imposed on the spectrum, the typical fluctuating-to-equilibrium magnetic field ratio is found to be of the order of 10 -10 . Physical mechanisms to obtain decay profiles of the spectra with increasing wavenumber due to dispersion and/or different forms of damping are investigated analytically in a cold fluid approximation and numerically, with a kinetic model. The mode dispersion due to the finite ion-gyrofrequency is identified as the leading effect determining the spectral profile shapes. It is found that the amplitude of fluctuations may be within a factor of the value suggested by the cold plasma model. The results from both models are presented and compared in low- and high-β regimes. 21 refs., 6 figs

  14. ESA DUE GlobVapour water vapor products: Validation

    Science.gov (United States)

    Schneider, Nadine; Schröder, Marc; Lindstrot, Ramus; Preusker, Rene; Stengel, Martin; ESA DUE GlobVapour Consortium

    2013-05-01

    The main objective of the European Space Agency (ESA) Data User Element (DUE) GlobVapour project was the development of multi-annual global water vapor data sets. Since water vapour is a key climate variable it is important to have a good understanding of its behavior in the climate system. The ESA DUE GlobVapour project provides water vapor data, including error estimates, based on carefully calibrated and inter-calibrated satellite radiances in response to user requirements for long time series satellite observations. ESA DUE GlobVapour total columnar water vapor (TCWV) products derived from GOME/SCIA/GOME-2 (1996-2008) and SSM/I+MERIS (2003-2008) have been validated for the mentioned period, using satellite-based (AIRS, ATOVS) and ground-based measurements (radiosondes and microwave radiometer). The validation results are discussed in the following. The technical specifications on bias (1 kg/m2 for SSMI+MERIS and 2 kg/m2 for GOME/SCIA/GOME-2) are generally met. For more information, documents and data download follow the link: www.globvapour.info.

  15. ESA DUE GlobVapour water vapor products: Validation

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, Nadine; Schroeder, Marc; Stengel, Martin [Deutscher Wetterdienst (DWD), KU22, Frankfurter Str. 135, 63067 Offenbach a. M (Germany); Lindstrot, Ramus; Preusker, Rene [Freie Universitaet Berlin (FUB), Carl-Heinrich-Becker-Weg 6-10, 12165 Berlin (Germany); Collaboration: ESA DUE GlobVapour Consortium

    2013-05-10

    The main objective of the European Space Agency (ESA) Data User Element (DUE) GlobVapour project was the development of multi-annual global water vapor data sets. Since water vapour is a key climate variable it is important to have a good understanding of its behavior in the climate system. The ESA DUE GlobVapour project provides water vapor data, including error estimates, based on carefully calibrated and inter-calibrated satellite radiances in response to user requirements for long time series satellite observations. ESA DUE GlobVapour total columnar water vapor (TCWV) products derived from GOME/SCIA/GOME-2 (1996-2008) and SSM/I+MERIS (2003-2008) have been validated for the mentioned period, using satellite-based (AIRS, ATOVS) and ground-based measurements (radiosondes and microwave radiometer). The validation results are discussed in the following. The technical specifications on bias (1 kg/m{sup 2} for SSMI+MERIS and 2 kg/m{sup 2} for GOME/SCIA/GOME-2) are generally met. For more information, documents and data download follow the link: www.globvapour.info.

  16. [Cutaneous leishmaniasis due to Leishmania infantum associated with HIV].

    Science.gov (United States)

    Diatta, B-A; Diallo, M; Diadie, S; Faye, B; Ndiaye, M; Hakim, H; Diallo, S; Seck, B; Niang, S-O; Kane, A; Dieng, M-T

    2016-10-01

    In Senegal, reported cases of cutaneous leishmaniasis are often due to Leishmania major. Immunosuppression related to HIV infection contributes to the emergence of leishmaniasis in humans and to cutaneous localization of viscerotropic species. We report the first observed case in Senegal of opportunistic cutaneous leishmaniasis due to Leishmania infantum associated with HIV. A 5-year-old boy presented crusted ulcerative lesions of the scalp and left forearm, together with axillary and cervical lymphadenopathy present for two months. Direct parasitological examination of the scalp and arm lesions, coupled with liquid aspiration of lymph nodes and bone marrow, enabled identification of amastigote forms of Leishmania. Polymerase chain reaction performed on skin, lymph node and bone marrow biopsy samples allowed identification of L. infantum. The child was positive for HIV1. Treatment of HIV infection and leishmaniasis resulted in clinical improvement. Co-infection with cutaneous leishmaniasis due to L. infantum and HIV is a complex combination in terms of the related therapeutic issues. The clinical and laboratory outcomes depend on restoration of immunity and on the efficacy, safety and availability of anti-leishmaniasis drugs. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  17. Economic losses occurring due to brucellosis in Indian livestock populations.

    Science.gov (United States)

    Singh, B B; Dhand, N K; Gill, J P S

    2015-05-01

    Brucellosis is a serious public health issue in India. Estimation of economic losses occurring due to brucellosis is required to help formulate prevention and control strategies, but has not been done in India. We estimated economic losses due to brucellosis by sourcing prevalence data from epidemiological surveys conducted in India. Data for livestock populations were obtained from official records. Probability distributions were used for many of the input parameters to account for uncertainty and variability. The analysis revealed that brucellosis in livestock is responsible for a median loss of US $ 3.4 billion (5th-95th percentile 2.8-4.2 billion). The disease in cattle and buffalo accounted for 95.6% of the total losses occurring due to brucellosis in livestock populations. The disease is responsible for a loss of US $ 6.8 per cattle, US$18.2 per buffalo, US $ 0.7 per sheep, US $ 0.5 per goat and US $ 0.6 per pig. These losses are additional to the economic and social consequences of the disease in humans. The results suggest that the disease causes significant economic losses in the country and should be controlled on a priority basis. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Readmissions due to traffic accidents at a general hospital

    Directory of Open Access Journals (Sweden)

    Luciana Paiva

    2015-08-01

    Full Text Available AbstractObjective: to verify the occurrence and the causes of hospital readmissions within a year after discharge from hospitalizations due to traffic accidents.Methods: victims of multiple traumas due to traffic accidents were included, who were admitted to an Intensive Care Unit. Sociodemographic data, accident circumstances, body regions affected and cause of readmission were collected from the patient histories.Results: among the 109 victims of traffic accidents, the majority were young and adult men. Most hospitalizations due to accidents involved motorcycle drivers (56.9%. The causes of the return to the hospital were: need to continue the surgical treatment (63.2%, surgical site infection (26.3% and fall related to the physical sequelae of the trauma (10.5%. The rehospitalization rate corresponded to 174/1,000 people/year.Conclusion: the hospital readmission rate in the study population is similar to the rates found in other studies. Victims of severe limb traumas need multiple surgical procedures, lengthier hospitalizations and extended rehabilitation.

  19. Recurrent iridocyclitis due to cotton fiber in anterior chamber.

    Science.gov (United States)

    Joshi, Rajesh S

    2016-01-01

    Cotton is commonly used during ophthalmic surgical procedure. Cotton fibers may get attracted to the instruments due to electrostatic forces and become adhered to the surface. With the introduction of these instruments during the surgical procedure cotton fiber may get entry into the eye. In the literature they have been infrequently reported due to insignificant effect on the ocular structures. We present a case of recurrent iridocyclitis due to cotton fiber in the anterior chamber. Patient was relived of his symptoms after removal. A 78-year-old male presented with pain, redness and blurring of right eye vision since last six months. The patient had undergone phacoemulsification with implantation of hydrophilic intraocular lens (IOL) six years earlier. Postoperative follow up was uneventful from his records till last 6 months. Slit-lamp examination revealed a cotton fiber in the anterior chamber touching the endothelium. Keratic precipitates were seen on the endothelium. Removal of the cotton fiber resulted in subsidence of inflammation. We recommend use of plastic eye and trolley drapes, lint free instrument wipes and use of needle cap to support the globe during creation of side port while performing phacoemulsification instead of cotton buds to avoid entry of cotton fiber into the anterior chamber. © NEPjOPH.

  20. [Neonatal staphylococcal epidermolysis due to maternal-fetal transmission].

    Science.gov (United States)

    Léauté-Labrèze, C; Sarlangue, J; Pedespan, L; Doermann, H P; Taïeb, A

    1999-10-01

    The staphylococcal scalded skin syndrome (SSSS) is due to exfoliative toxins A or B excreted by some strains of Staphylococcus aureus. This syndrome is exceptional in the first hours of life. We report a case of SSSS due to materno-fetal infection. At 31 weeks of pregnancy a 40-year-old mother was febrile (39 degrees C) and a premature rupture of the amniotic sac occurred the following day. SSSS was diagnosed at 6 hours of life in the newborn, a 1760 g female. Staphylococcus aureus grew on the blood and vaginal bacterial cultures of the mother, as well as, from cultures of skin, nose, throat, and umbilical catheter in the newborn. The strains of Staphylococcus aureus isolated in the mother and the child had identical characteristic antibiotype and genotype by Random-PCR. The genes for both exfoliations A and B were present. Epidermization was rapidly obtained and no septicemia or septic complication was noted. Staphylococcus aureus is usually responsible for nosocomial infections which occur in the early newborn period. In most cases, the infection is transmitted by a carrier who manipulates the child (family, visitors, nurse or medical staff). In our case, onset of SSSS early after birth suggested a perinatal transmission, due to lower genital tract infection in the mother. The presence of SSSS in the child and not in the mother may be explained by a massive perinatal infection and low elimination of the toxin in the newborn resulting in higher concentrations of exfoliative toxins in the blood.

  1. AN ANALYTICAL STUDY OF DEATHS DUE TO POISONING IN VISAKHAPATNAM

    Directory of Open Access Journals (Sweden)

    V. Chandrasekhar

    2017-11-01

    Full Text Available BACKGROUND The aim of this study was to determine and classify the various types of poisoning deaths as seen at Andhra Medical College Mortuary, Visakhapatnam city. MATERIALS AND METHODS This is a retrospective study of all the deaths due to poisoning seen in the Department of Forensic Medicine & Toxicology, Andhra Medical College, Visakhapatnam City over a 15 year period (January 2001‐December 2015 as recorded in the autopsy registers and postmortem reports of the department. RESULTS Poisoning is one of the commonest methods of committing suicide especially in developing countries like India. A total of 22475 autopsies were done during the period. Two thousand seventy four cases representing 9.23% of all bodies received by the mortuary were deaths due to poisoning. Organophosphate compounds were the most commonly 78.98% abused substance. The common motive of poisoning was suicidal 93.43%with male to female ratio 6.69:1.Peak incidence was observed in the age group 21-40 years. Type of poison consumed, socioeconomic status and place of household are also ascertained. CONCLUSION This study shows the pattern of poisoning deaths in Visakhapatnam and this preliminary data will provide a baseline for future research and help in formulating policies to prevent deaths due to poisoning.

  2. Reduction of artefacts due to missing projections using OSEM

    International Nuclear Information System (INIS)

    Hutton, B.F.; Kyme, A.; Choong, K.

    2002-01-01

    Full text: It is well recognised that missing or corrupted projections can result in artefacts. This occasionally occurs due to errors in data transfer from acquisition memory to disk. A possible approach for reducing these artefacts was investigated, Using ordered subsets expectation maximization (OSEM) the iterative reconstruction proceeds by progressively including additional projections until a single iteration is complete. Clinically useful results can be obtained using a small subset size in a single iteration. Stopping prior to the complete iteration so as to avoid inclusion of missing or corrupted data should provide a 'partial' reconstruction with minimal artefacts. To test this hypothesis projections were selectively removed from a complete data set (2, 4, 8, 12 adjacent projections) and reconstructions were performed using both filtered back projection (FBP) and OSEM. To maintain a constant number of sub-iterations in OSEM an equal number of duplicate projections were substituted for the missing projections. Both 180 and 360 degrees reconstructions with missing data were compared with reconstruction for the complete data using sum of absolute differences. Results indicate that missing data causes artefacts for both FBP and OSEM however the severity of artefacts is significantly reduced using OSEM. The effect of missing data is generally greater for 180 degrees acquisition. OSEM is recommended for minimising reconstruction artefacts due to missing projections. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  3. Motion of the esophagus due to cardiac motion.

    Directory of Open Access Journals (Sweden)

    Jacob Palmer

    Full Text Available When imaging studies (e.g. CT are used to quantify morphological changes in an anatomical structure, it is necessary to understand the extent and source of motion which can give imaging artifacts (e.g. blurring or local distortion. The objective of this study was to assess the magnitude of esophageal motion due to cardiac motion. We used retrospective electrocardiogram-gated contrast-enhanced computed tomography angiography images for this study. The anatomic region from the carina to the bottom of the heart was taken at deep-inspiration breath hold with the patients' arms raised above their shoulders, in a position similar to that used for radiation therapy. The esophagus was delineated on the diastolic phase of cardiac motion, and deformable registration was used to sequentially deform the images in nearest-neighbor phases among the 10 cardiac phases, starting from the diastolic phase. Using the 10 deformation fields generated from the deformable registration, the magnitude of the extreme displacements was then calculated for each voxel, and the mean and maximum displacement was calculated for each computed tomography slice for each patient. The average maximum esophageal displacement due to cardiac motion for all patients was 5.8 mm (standard deviation: 1.6 mm, maximum: 10.0 mm in the transverse direction. For 21 of 26 patients, the largest esophageal motion was found in the inferior region of the heart; for the other patients, esophageal motion was approximately independent of superior-inferior position. The esophagus motion was larger at cardiac phases where the electrocardiogram R-wave occurs. In conclusion, the magnitude of esophageal motion near the heart due to cardiac motion is similar to that due to other sources of motion, including respiratory motion and intra-fraction motion. A larger cardiac motion will result into larger esophagus motion in a cardiac cycle.

  4. Analysis of 3-D Propagation Effects Due to Environmental Variability

    Science.gov (United States)

    2014-09-30

    D Propagation Effects Due to Environmental Variability 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...beamformer applied to the travel time data extracted over a 400m aperture centered at -1km cross-range. These results clearly display horizontal...460Hz at a depth of 50m (left panel), and plane-wave beamformed response from this data over a 400m aperture centered at -1km cross-range (right

  5. Mine water quality deterioration due to acid mine drainage

    Science.gov (United States)

    Singh, Gurdeep

    1987-03-01

    Water quality deterioration due to acid mine drainage is of concern in the northeastern coalfield of India as the water in this area is severely polluted. The mine drainage water emanating from various collieries are highly acidic in character and contain high hardness, sulphate, total dissolved solids and iron coupled with low pH values—which further results in contamination of trace (heavy) metals at significant levels. Trace metals are highly toxic and undesirable and are injurious to human health. These acidic waters are also typically hard in character because of iron sulphate content rather than common Ca-Mg bicarbonate type hardness.

  6. Optical loss due to diffraction by concentrator Fresnel lenses

    International Nuclear Information System (INIS)

    Hornung, Thorsten; Nitz, Peter

    2014-01-01

    Fresnel lenses are widely used in concentrating photovoltaic (CPV) systems as a primary optical element. They focus sunlight on small solar cells or on the entrance apertures of secondary optical elements. A Fresnel lens consists of several prism rings and diffraction by these prism rings is unavoidable. Some of the light that would reach a designated target area according to geometric optics will miss it due to diffraction. This diffraction loss may be of relevant magnitude for CPV applications. The results of published analytical calculations are evaluated, discussed, and compared to computer simulations and measurements

  7. Spin Depolarization due to Beam-Beam Interaction in NLC

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Kathleen A

    2001-01-04

    Calculations of spin depolarization effects due to the beam-beam interaction are presented for several NLC designs. The depolarization comes from both classical (Bargmann-Michel-Telegdi precession) and quantum (Sokolov-Ternov spin-flip) effects. It is anticipated that some physics experiments at future colliders will require a knowledge of the polarization to better than 0.5% precision. We compare the results of CAIN simulations with the analytic estimates of Yokoya and Chen for head-on collisions. We also study the effects of transverse offsets and beamstrahlung-induced energy spread.

  8. Risk of Therapeutic Failure due to Ineffectiveness of Medication

    Science.gov (United States)

    Woring, Virginia E.

    2011-01-01

    Given that terrestrial medical practices must be used as the basis for drug choice and use on missions, there is a possibility that medications used will be ineffective or inappropriate for the actual circumstances encountered on missions. Because the human body undergoes a variety of physiological changes during spaceflight, there is a risk that terrestrial medications may not perform as expected when used during spaceflight. Alterations in physiology due to spaceflight could result in unexpected drug action on the body (pharmacodynamics) or in unusual drug absorption, distribution, metabolism or excretion (pharmacokinetics). The spaceflight environment may also have direct effects on stored drugs themselves, leading to premature inactivation or degradation of stored drugs.

  9. Nonlinear gain suppression in semiconductor lasers due to carrier heating

    International Nuclear Information System (INIS)

    Willatzen, M.; Uskov, A.; Moerk, J.; Olesen, H.; Tromborg, B.; Jauho, A.P.

    1991-01-01

    We present a simple model for carrier heating in semiconductor lasers, from which the temperature dynamics of the electron and hole distributions can be calculated. Analytical expressions for two new contributions to the nonlinear gain coefficient ε are derived, which reflect carrier heating due to stimulated emission and free carrier absorption. In typical cases, carrier heating and spectral holeburning are found to give comparable contributions to nonlinear gain suppression. The results are in good agreement with recent measurements on InGaAsP laser diodes. (orig.)

  10. Alterations to groundwater recharge due to anthropogenic landscape change

    Science.gov (United States)

    Han, Dongmei; Currell, Matthew J.; Cao, Guoliang; Hall, Benjamin

    2017-11-01

    The impacts of anthropogenic modifications to the landscape on groundwater recharge rates, locations, and mechanisms are reviewed. The two major categories of change examined are conversion of land for agriculture and urbanization, both of which have significant effects on groundwater recharge. Techniques for identifying and quantifying the changes in recharge due to these impacts are discussed. Land-clearing for agriculture and surface water transfer for irrigation have resulted in order of magnitude increases in recharge rates in many semi-arid regions worldwide, causing ongoing land and water salinization and water-logging problems. While increased recharge by irrigation return flow may alleviate shallow groundwater depletion in some settings, this is complicated by the effect of unsaturated zone thickening, which reduces the fraction of potential recharge becoming actual recharge, and may result in new water quality risks such as nitrate contamination. Expansion of urban and peri-urban land and their associated surface and sub-surface infrastructure results in complex water balance changes that re-distribute groundwater recharge locations, modify recharge mechanism(s) and result in variable impacts on recharge rates (e.g., overall net decrease, increase or minimal change) and quality. While changes to groundwater recharge resulting from conversion of land for agriculture are relatively well understood, less is documented about the changes resulting from urbanization, due to a paucity of data from field-based studies. Two case studies from Beijing, China and Melbourne Australia are examined, which highlight these impacts and demonstrate some potential methodological techniques for this topic.

  11. Resolution proposition aiming to create an inquiry commission on the capacities and the financial results of the Total Group, on the resources use, the industrial policy and on the employment, wages and country planing policy, as on the social and environmental liabilities. (refer to the economical, environmental and country affairs commission, for lack of special commission in due time by the articles 30 and 31 of the regulation)

    International Nuclear Information System (INIS)

    2005-03-01

    This document denounces the Total Group policy oriented to the profit and reveals the resulting environmental and social negative effects. It proposes the creation of an inquiry commission on the Group policy activities. (A.L.B.)

  12. Earth modeling and estimation of the local seismic ground motion due to site geology in complex volcanoclastic areas

    Directory of Open Access Journals (Sweden)

    V. Di Fiore

    2002-06-01

    Full Text Available Volcanic areas often show complex behaviour as far as seismic waves propagation and seismic motion at surface are concerned. In fact, the finite lateral extent of surface layers such as lava flows, blocks, differential welding and/or zeolitization within pyroclastic deposits, introduces in the propagation of seismic waves effects such as the generation of surface waves at the edge, resonance in lateral direction, diffractions and scattering of energy, which tend to modify the amplitude as well as the duration of the ground motion. The irregular topographic surface, typical of volcanic areas, also strongly influences the seismic site response. Despite this heterogeneity, it is unfortunately a common geophysical and engineering practice to evaluate even in volcanic environments the subsurface velocity field with monodimensional investigation method (i.e. geognostic soundings, refraction survey, down-hole, etc. prior to the seismic site response computation which in a such cases is obviously also made with 1D algorithms. This approach often leads to highly inaccurate results. In this paper we use a different approach, i.e. a fully 2D P-wave Çturning rayÈ tomographic survey followed by 2D seismic site response modeling. We report here the results of this approach in three sites located at short distance from Mt. Vesuvius and Campi Flegrei and characterized by overburdens constituted by volcanoclastic deposits with large lateral and vertical variations of their elastic properties. Comparison between 1D and 2D Dynamic Amplification Factor shows in all reported cases entirely different results, both in terms of peak period and spectral contents, as expected from the clear bidimensionality of the geological section. Therefore, these studies suggest evaluating carefully the subsoil geological structures in areas characterized by possible large lateral and vertical variations of the elastic properties in order to reach correct seismic site response

  13. The prognosis of retinal detachment due to lattice degeneration.

    Science.gov (United States)

    Benson, W E; Morse, P H

    1978-09-01

    In a series of 553 consecutive retinal detachments, 29% (120) were due to lattice degeneration. Forty-five percent of these were due to atrophic holes in the lattice degeneration and 55% were due to tears caused by traction posterior to or at the end of a patch of lattice. In phakic patients, retinal detachments due to atrophic holes were most common in young myopes. Detachments due to traction tears were seen in older, less myopic patients. The incidence of massive periretinal proliferation was less (5%) in detachments due to lattice degeneration than in detachments not due to lattice degeneration (6.5%).

  14. Energy Loss in Pulse Detonation Engine due to Fuel Viscosity

    Directory of Open Access Journals (Sweden)

    Weipeng Hu

    2014-01-01

    Full Text Available Fluid viscosity is a significant factor resulting in the energy loss in most fluid dynamical systems. To analyze the energy loss in the pulse detonation engine (PDE due to the viscosity of the fuel, the energy loss in the Burgers model excited by periodic impulses is investigated based on the generalized multisymplectic method in this paper. Firstly, the single detonation energy is simplified as an impulse; thus the complex detonation process is simplified. And then, the symmetry of the Burgers model excited by periodic impulses is studied in the generalized multisymplectic framework and the energy loss expression is obtained. Finally, the energy loss in the Burgers model is investigated numerically. The results in this paper can be used to explain the difference between the theoretical performance and the experimental performance of the PDE partly. In addition, the analytical approach of this paper can be extended to the analysis of the energy loss in other fluid dynamic systems due to the fluid viscosity.

  15. Irradiation deformation due to SIPA induced dislocation anisotropy

    International Nuclear Information System (INIS)

    Woo, CH.

    1980-02-01

    A contribution to irradiation deformation resulting from the stress-induced preferred adsorption (SIPA) effect is considered. SIPA causes a variation of the growth rates of irradiation-generated dislocation loops, according to the alignment of their Burgers vectors with respect to the applied stress. A prolinged period under an applied stress then creates an anisotropic dislocation structure in which the majority of dislocations have their Burgers vectors in alignment with the stress. In the presence of 'neutral' sinks, the resulting anisotropic dislocation structure causes plastic deformation similar to the way in which irradiation growth occurs in zirconium. This mechanism is called SIPA-induced growth (SIG). We have shown that SIG is very significant in comparison to SIPA, except when little or no loop growth has occurred during the period the stress is applied. This report contains the detailed formulation and derivation of the formulae for the evaluation of the contribution due to SIG. (auth)

  16. Springing Response Due to Directional Wave Field Excitation

    DEFF Research Database (Denmark)

    Vidic-Perunovic, Jelena; Jensen, Jørgen Juncher

    2004-01-01

    This paper analyses the wave-induced high-frequency bending moment response of ships, denoted springing. The aim is to predict measured severe springing responses in a large bulk carrier. It is shown that the most important springing contribution is due to the resultant second order excitation...... in multidirectional sea. The incident pressure field from the second order bidirectional wave field is derived, including the non-linear cross-coupling terms between the two wave systems (e.g. wind driven waves and swell). The resulting effect of the super-harmonic cross-coupling interaction terms on the springing...... response is discussed. An example with opposing waves is given, representing probably the 'worst' case for energy exchange between the wave systems. Theoretical predictions of standard deviation of wave- and springing-induced stress amidships are compared with full-scale measurements for a bulk carrier....

  17. Submarine slope failures due to pipe structure formation.

    Science.gov (United States)

    Elger, Judith; Berndt, Christian; Rüpke, Lars; Krastel, Sebastian; Gross, Felix; Geissler, Wolfram H

    2018-02-19

    There is a strong spatial correlation between submarine slope failures and the occurrence of gas hydrates. This has been attributed to the dynamic nature of gas hydrate systems and the potential reduction of slope stability due to bottom water warming or sea level drop. However, 30 years of research into this process found no solid supporting evidence. Here we present new reflection seismic data from the Arctic Ocean and numerical modelling results supporting a different link between hydrates and slope stability. Hydrates reduce sediment permeability and cause build-up of overpressure at the base of the gas hydrate stability zone. Resulting hydro-fracturing forms pipe structures as pathways for overpressured fluids to migrate upward. Where these pipe structures reach shallow permeable beds, this overpressure transfers laterally and destabilises the slope. This process reconciles the spatial correlation of submarine landslides and gas hydrate, and it is independent of environmental change and water depth.

  18. Tension Pneumatocele due to Enterobacter gergoviae Pneumonia: A Case Report

    Directory of Open Access Journals (Sweden)

    Emeka B. Kesieme

    2012-01-01

    Full Text Available Pneumatocele formation is a known complication of pneumonia. Very rarely, they may increase markedly in size, causing cardiorespiratory compromise. Many organisms have been implicated in the pathogenesis of this disease; however, this is the first report of tension pneumatocele resulting from Enterobacter gergoviae pneumonia. We report a case of a 3-month-old Nigerian male child who developed two massive tension pneumatoceles while on treatment for postpneumonic empyema due to Enterobacter gergoviae pneumonia. Tube thoracostomy directed into both pneumatocele resulted in complete resolution and recovery. Enterobacter gergoviae is a relevant human pathogen, capable of causing complicated pneumonia with fatal outcome if not properly managed. In developing countries where state-of the-art radiological facilities and expertise for prompt thoracic intervention are lacking, there is still room for nonoperative management of tension pneumatocele especially in very ill children.

  19. Concrete cover cracking due to uniform reinforcement corrosion

    DEFF Research Database (Denmark)

    Solgaard, Anders Ole Stubbe; Michel, Alexander; Geiker, Mette Rica

    2013-01-01

    Service life design (SLD) is an important tool for civil engineers to ensure that the structural integrity and functionality of the structure is not compromised within a given time frame, i.e. the service life. In SLD of reinforced concrete structures, reinforcement corrosion is of major concern...... and reinforcement de-passivation is a frequently used limit state. The present paper investigates an alternative limit state: corrosion-induced cover cracking. Results from numerical simulations of concrete cover cracking due to reinforcement corrosion are presented. The potential additional service life...... is calculated using literature data on corrosion rate and Faraday’s law. The parameters varied comprise reinforcement diameter, concrete cover thickness and concrete material properties, viz. concrete tensile strength and ductility (plain concrete and fibre reinforced concrete). Results obtained from...

  20. Changes in Dimethyl Sulfide Oceanic Distribution due to Climate Change

    Energy Technology Data Exchange (ETDEWEB)

    Cameron-Smith, P; Elliott, S; Maltrud, M; Erickson, D; Wingenter, O

    2011-02-16

    Dimethyl sulfide (DMS) is one of the major precursors for aerosols and cloud condensation nuclei in the marine boundary layer over much of the remote ocean. Here they report on coupled climate simulations with a state-of-the-art global ocean biogeochemical model for DMS distribution and fluxes using present-day and future atmospheric CO{sub 2} concentrations. They find changes in zonal averaged DMS flux to the atmosphere of over 150% in the Southern Ocean. This is due to concurrent sea ice changes and ocean ecosystem composition shifts caused by changes in temperature, mixing, nutrient, and light regimes. The largest changes occur in a region already sensitive to climate change, so any resultant local CLAW/Gaia feedback of DMS on clouds, and thus radiative forcing, will be particularly important. A comparison of these results to prior studies shows that increasing model complexity is associted with reduced DMS emissions at the equator and increased emissions at high latitudes.

  1. Degradation and crosslinking of PTFE due to irradiation

    International Nuclear Information System (INIS)

    Tutiya, Mituaki

    1995-01-01

    In this report, we summarized all our experimental results concerning about the effects of Co-60 γ rays irradiation on polytetrafluoroethylene (PTFE). The NMR spectra, the mechanical properties and others of PTFE were measured. The increase in the degree of crystallinity, the lowering of the 19degC transition temperature and that of the melting temperature due to irradiation were observed. The effect of post-irradiation heat treatment were also observed. In each case, the main causes of these effects were attributed to the radiation-induced main chain scission. In the case of PTFE irradiated at 320-360degC in vacuum, we found that the effect of radiation-induced crosslinking were observed. By using our new theories, these experimental results which were measured in the crystalline and the amorphous regions of the irradiated PTFE were discussed, and a satisfactory agreement between the theories and the experiments was obtained. (author)

  2. Crystallographic changes in lead zirconate titanate due to neutron irradiation

    Directory of Open Access Journals (Sweden)

    Alexandra Henriques

    2014-11-01

    Full Text Available Piezoelectric and ferroelectric materials are useful as the active element in non-destructive monitoring devices for high-radiation areas. Here, crystallographic structural refinement (i.e., the Rietveld method is used to quantify the type and extent of structural changes in PbZr0.5Ti0.5O3 after exposure to a 1 MeV equivalent neutron fluence of 1.7 × 1015 neutrons/cm2. The results show a measurable decrease in the occupancy of Pb and O due to irradiation, with O vacancies in the tetragonal phase being created preferentially on one of the two O sites. The results demonstrate a method by which the effects of radiation on crystallographic structure may be investigated.

  3. Report on Results 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report discusses work being carried out in Norway to promote energy efficiency and the production of new renewable energy. An overall review of the quantifiable results of last year's activities at national level is available. It will serve to initiate an annual reporting tradition. The report represents a step towards an ongoing process for improved targeting and management of national efforts. During the course of the year 2000, NVE has evaluated and adjusted its activities and established a system involving indicators and reporting procedures. It is also important to take notice of the long-term work being undertaken to influence people's attitudes, even though this work is difficult to assess. NVE is investing in i.a. measures aimed at children and young people. Apart from directly influencing future energy users, this investment is also having an effect due to the children's encouragement of their parents to engage in more energy and environment-friendly behaviour. Published in 2000, the IEA report ''Trends in Norwegian Stationary Energy Use'' shows that total Norwegian energy consumption per GDP is not much higher than in other IEA countries, when adjusted for cold climate and industrial structure. However, Norwegians do stand out as intensive users of electricity. The IEA report shows a reduction of 10 TWh in energy usage when compared to the projected post 1990 figures. Energy efficiency activities have contributed towards this reduction. However, the potential for a more rational use of energy in Norway is still substantial and well documented. Based on experience most enterprises could save around 10% of energy used just by making changes to their operations, i.e. without major investments. Furthermore, the potential is growing because of massive technological developments in respect of energy usage, production and distribution. With this in mind, it is necessary to take full advantage of the extensive knowledge

  4. HIV due to female sex work: regional and global estimates.

    Science.gov (United States)

    Prüss-Ustün, Annette; Wolf, Jennyfer; Driscoll, Tim; Degenhardt, Louisa; Neira, Maria; Calleja, Jesus Maria Garcia

    2013-01-01

    Female sex workers (FSWs) are at high risk of HIV infection. Our objective was to determine the proportion of HIV prevalence in the general female adult population that is attributable to the occupational exposure of female sex work, due to unprotected sexual intercourse. Population attributable fractions of HIV prevalence due to female sex work were estimated for 2011. A systematic search was conducted to retrieve required input data from available sources. Data gaps of HIV prevalence in FSWs for 2011 were filled using multilevel modeling and multivariate linear regression. The fraction of HIV attributable to female sex work was estimated as the excess HIV burden in FSWs deducting the HIV burden in FSWs due to injecting drug use. An estimated fifteen percent of HIV in the general female adult population is attributable to (unsafe) female sex work. The region with the highest attributable fraction is Sub Saharan Africa, but the burden is also substantial for the Caribbean, Latin America and South and Southeast Asia. We estimate 106,000 deaths from HIV are a result of female sex work globally, 98,000 of which occur in Sub-Saharan Africa. If HIV prevalence in other population groups originating from sexual contact with FSWs had been considered, the overall attributable burden would probably be much larger. Female sex work is an important contributor to HIV transmission and the global HIV burden. Effective HIV prevention measures exist and have been successfully targeted at key populations in many settings. These must be scaled up. FSWs suffer from high HIV burden and are a crucial core population for HIV transmission. Surveillance, prevention and treatment of HIV in FSWs should benefit both this often neglected vulnerable group and the general population.

  5. HIV due to female sex work: regional and global estimates.

    Directory of Open Access Journals (Sweden)

    Annette Prüss-Ustün

    Full Text Available Female sex workers (FSWs are at high risk of HIV infection. Our objective was to determine the proportion of HIV prevalence in the general female adult population that is attributable to the occupational exposure of female sex work, due to unprotected sexual intercourse.Population attributable fractions of HIV prevalence due to female sex work were estimated for 2011. A systematic search was conducted to retrieve required input data from available sources. Data gaps of HIV prevalence in FSWs for 2011 were filled using multilevel modeling and multivariate linear regression. The fraction of HIV attributable to female sex work was estimated as the excess HIV burden in FSWs deducting the HIV burden in FSWs due to injecting drug use.An estimated fifteen percent of HIV in the general female adult population is attributable to (unsafe female sex work. The region with the highest attributable fraction is Sub Saharan Africa, but the burden is also substantial for the Caribbean, Latin America and South and Southeast Asia. We estimate 106,000 deaths from HIV are a result of female sex work globally, 98,000 of which occur in Sub-Saharan Africa. If HIV prevalence in other population groups originating from sexual contact with FSWs had been considered, the overall attributable burden would probably be much larger.Female sex work is an important contributor to HIV transmission and the global HIV burden. Effective HIV prevention measures exist and have been successfully targeted at key populations in many settings. These must be scaled up.FSWs suffer from high HIV burden and are a crucial core population for HIV transmission. Surveillance, prevention and treatment of HIV in FSWs should benefit both this often neglected vulnerable group and the general population.

  6. Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae

    Directory of Open Access Journals (Sweden)

    Konrads Christian

    2016-01-01

    Full Text Available Introduction: Septic olecranon bursitis due to atypical mycobacteria is rare. An insidious beginning can delay diagnosis and treatment. Antibacterial therapy recommendations are not well-defined for bursitis caused by atypical mycobacteria. We present a rare case of olecranon bursitis caused by Mycobacterium gordonae, reporting our experiences regarding pathogen identification and antibiotic therapy, which differs from regimes used in common septic bursitis mostly caused by staphylococcus aureus. Methods: A 35-year-old male with bursitis olecrani received open bursectomy. Microbiological culture did not reveal bacteria. Due to wound healing complications revision surgery was performed four weeks postoperatively. Finally, Mycobacterium gordonae was identified by PCR and an antibiogram could be developed. A triple antimicrobial combination therapy with Rifampicin, Clarithromycin, and Ethambutol was administered systemically for 12 months. The patient was followed-up for 24 months. Results: After the second operation with pathogen identification and antibiotic combination therapy the wound healed without any additional complications. At last follow-up 24 months after the first surgery with bursectomy and 23 months after revision surgery with debridement, the patient was still pain free with no significant clinical findings or tenderness to touch at the operation site. Elbow range of motion was full. Discussion: As septic bursitis can be caused by many different and sometimes rare and difficult to identify bacteria, intraoperative probes should be taken and histopathological and microbiological analysis should be conducted, including PCR. In a young man with olecranon bursitis due to Mycobacterium gordonae surgical treatment and an antibiotic combination therapy showed a good clinical outcome after one and two years.

  7. Theoretical basis for convective invigoration due to increased aerosol concentration

    Directory of Open Access Journals (Sweden)

    Z. J. Lebo

    2011-06-01

    Full Text Available The potential effects of increased aerosol loading on the development of deep convective clouds and resulting precipitation amounts are studied by employing the Weather Research and Forecasting (WRF model as a detailed high-resolution cloud resolving model (CRM with both detailed bulk and bin microphysics schemes. Both models include a physically-based activation scheme that incorporates a size-resolved aerosol population. We demonstrate that the aerosol-induced effect is controlled by the balance between latent heating and the increase in condensed water aloft, each having opposing effects on buoyancy. It is also shown that under polluted conditions, increases in the CCN number concentration reduce the cumulative precipitation due to the competition between the sedimentation and evaporation/sublimation timescales. The effect of an increase in the IN number concentration on the dynamics of deep convective clouds is small and the resulting decrease in domain-averaged cumulative precipitation is shown not to be statistically significant, but may act to suppress precipitation. It is also shown that even in the presence of a decrease in the domain-averaged cumulative precipitation, an increase in the precipitation variance, or in other words, andincrease in rainfall intensity, may be expected in more polluted environments, especially in moist environments.

    A significant difference exists between the predictions based on the bin and bulk microphysics schemes of precipitation and the influence of aerosol perturbations on updraft velocity within the convective core. The bulk microphysics scheme shows little change in the latent heating rates due to an increase in the CCN number concentration, while the bin microphysics scheme demonstrates significant increases in the latent heating aloft with increasing CCN number concentration. This suggests that even a detailed two-bulk microphysics scheme, coupled to a detailed activation scheme, may not be

  8. Heat Loads Due To Small Penetrations In Multilayer Insulation Blankets

    Science.gov (United States)

    Johnson, W. L.; Heckle, K. W.; E Fesmire, J.

    2017-12-01

    The main penetrations (supports and piping) through multilayer insulation systems for cryogenic tanks have been previously addressed by heat flow measurements. Smaller penetrations due to fasteners and attachments are now experimentally investigated. The use of small pins or plastic garment tag fasteners to ease the handling and construction of multilayer insulation (MLI) blankets goes back many years. While it has long been understood that penetrations and other discontinuities degrade the performance of the MLI blanket, quantification of this degradation has generally been lumped into gross performance multipliers (often called degradation factors or scale factors). Small penetrations contribute both solid conduction and radiation heat transfer paths through the blanket. The conduction is down the stem of the structural element itself while the radiation is through the hole formed during installation of the pin or fastener. Analytical models were developed in conjunction with MLI perforation theory and Fourier’s Law. Results of the analytical models are compared to experimental testing performed on a 10 layer MLI blanket with approximately 50 small plastic pins penetrating the test specimen. The pins were installed at ∼76-mm spacing inches in both directions to minimize the compounding of thermal effects due to localized compression or lateral heat transfer. The testing was performed using a liquid nitrogen boil-off calorimeter (Cryostat-100) with the standard boundary temperatures of 293 K and 78 K. Results show that the added radiation through the holes is much more significant than the conduction down the fastener. The results are shown to be in agreement with radiation theory for perforated films.

  9. Nonlinear wave damping due to multi-plasmon resonances

    Science.gov (United States)

    Brodin, G.; Ekman, R.; Zamanian, J.

    2018-02-01

    For short wavelengths, it is well known that the linearized Wigner–Moyal equation predicts wave damping due to wave-particle interaction, where the resonant velocity shifted from the phase velocity by a velocity {v}q={{\\hslash }}k/2m. Here {{\\hslash }} is the reduced Planck constant, k is the wavenumber and m is the electron mass. Going beyond linear theory, we find additional resonances with velocity shifts {{nv}}q,n=2,3, \\ldots , giving rise to a new wave-damping mechanism that we term multi-plasmon damping, as it can be seen as the simultaneous absorption (or emission) of multiple plasmon quanta. Naturally this wave damping is not present in classical plasmas. For a temperature well below the Fermi temperature, if the linear (n = 1) resonant velocity is outside the Fermi sphere, the number of linearly resonant particles is exponentially small, while the multi-plasmon resonances can be located in the bulk of the distribution. We derive sets of evolution equations for the case of two-plasmon and three-plasmon resonances for Langmuir waves in the simplest case of a fully degenerate plasma. By solving these equations numerically for a range of wave-numbers we find the corresponding damping rates, and we compare them to results from linear theory to estimate the applicability. Finally, we discuss the effects due to a finite temperature.

  10. CO2: EDF's competitiveness is due to nuclear power

    International Nuclear Information System (INIS)

    Anon.

    2003-01-01

    The CO 2 emissions of EDF group (EDF-France + EDF-energy (UK) + Hidrocantabrico (Spain) + EnBW (Germany)) soared by 53% in 2002 which is due to the purchase of british and spanish electricity sub-companies using fossil energies. Despite this sharp increase EDF remains one of the most competitive electricity companies in Europe concerning greenhouse gas emissions. EDF group is the first electricity company in Europe, it generates 22% of the electricity produced in E.U and contributes to CO 2 emissions with a rate of 101 Kg CO 2 /MWh which 3 times less than the average rate of 20 other European companies (358 Kg CO 2 /MWh). This result is due to the large part of nuclear power in the French energy mix. The best electricity companies as far as CO 2 emissions are concerned are Statkraft (Norway) with 0 Kg CO 2 /MWh (100% hydrology) and British-energy (U.K) with 75 Kg CO 2 /MWh (75% nuclear power). At the other end we have the DEI company (Greece) with 863 Kg CO 2 /MWh (100% lignite). (A.C.)

  11. Blepharitis due to in a cat from northern Portugal

    Directory of Open Access Journals (Sweden)

    Paulo Pimenta

    2015-07-01

    Full Text Available Case summary We report a clinical case of blepharitis due to Cryptococcus neoformans yeasts in a 2-year-old stray cat from northern Portugal (Vila Real without concurrent naso-ocular signs. Ophthalmological examination revealed mucopurulent discharge from an open wound in the right upper and lower lids. Slit-lamp biomicroscopy showed a normal anterior segment, and intraocular pressure was within the normal reference interval. No fundoscopic alterations were detected in either eye by direct and indirect ophthalmoscopic examination. Cytological examination of an appositional smear showed numerous polymorphic neutrophils and macrophages, together with spherical yeast cells compatible with Cryptococcus species. Molecular analysis by means of PCR and restriction fragment length polymorphism identified C neoformans genotype VNI. The cat was treated with itraconazole, and amoxicillin and clavulanic acid, combined with a commercial ear ointment and an imidacloprid/moxidectin spot-on application for bilateral parasitic otitis caused by Otodectes cynotis . One month after treatment, the clinical signs were completely resolved. Localised cutaneous lesions, as in the present case, probably result from contamination of cat-scratch injuries with viable encapsulated yeasts. Relevance and novel information This is, to the best of our knowledge, the first clinical report of feline blepharitis due to C neoformans without concurrent naso-ocular signs. The current findings, together with those from recent reports of the infection in domestic animals, should alert the veterinary community both in Portugal and in Europe to this underdiagnosed disease.

  12. Pancreatic Pseudocyst Ruptured due to Acute Intracystic Hemorrhage

    Directory of Open Access Journals (Sweden)

    Kunishige Okamura

    2017-12-01

    Full Text Available Rupture of pancreatic pseudocyst is one of the rare complications and usually results in high mortality. The present case was a rupture of pancreatic pseudocyst that could be treated by surgical intervention. A 74-year-old man developed abdominal pain, vomiting, and diarrhea, and he was diagnosed with cholecystitis and pneumonia. Three days later, acute pancreatitis occurred and computed tomography (CT showed slight hemorrhage in the cyst of the pancreatic tail. After another 10 days, CT showed pancreatic cyst ruptured due to intracystic hemorrhage. Endoscopic retrograde cholangiopancreatography revealed leakage of contrast agent from pancreatic tail cyst to enclosed abdominal cavity. His left hypochondrial pain was increasing, and CT showed rupture of the cyst of the pancreatic tail into the peritoneal cavity was increased in 10 days. CT showed also two left renal tumors. Therefore we performed distal pancreatectomy with concomitant resection of transverse colon and left kidney. We histopathologically diagnosed pancreatic pseudocyst ruptured due to intracystic hemorrhage and renal cell carcinoma. Despite postoperative paralytic ileus and fluid collection at pancreatic stump, they improved by conservative management and he could be discharged on postoperative day 29. He has achieved relapse-free survival for 6 months postoperatively. The mortality of pancreatic pseudocyst rupture is very high if some effective medical interventions cannot be performed. It should be necessary to plan appropriate treatment strategy depending on each patient.

  13. pH variations during diafiltration due to buffer nonidealities.

    Science.gov (United States)

    Baek, Youngbin; Yang, Deyu; Singh, Nripen; Arunkumar, Abhiram; Ghose, Sanchayita; Li, Zheng Jian; Zydney, Andrew L

    2017-11-01

    Diafiltration is used for final formulation of essentially all biotherapeutics. Several studies have demonstrated that buffer/excipient concentrations in the final diafiltered product can be different than that in the diafiltration buffer due to interactions between buffer species and the protein product. However, recent work in our lab has shown variations in solution pH that are largely independent of the protein concentration during the first few diavolumes. Our hypothesis is that these pH variations are due to nonidealities in the acid-base equilibrium coefficient. A model was developed for the diafiltration process accounting for the ionic strength dependence of the pK a . Experimental results obtained using phosphate and histidine buffers were in excellent agreement with model predictions. A decrease in ionic strength leads to an increase in the pK a for the phosphate buffer, causing a shift in the solution pH, even under conditions where the initial feed and the diafiltration buffer are at the same pH. This effect could be eliminated by matching the ionic strength of the feed and diafiltration buffer. The experimental data and model provide new insights into the factors controlling the pH profile during diafiltration processes. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1555-1560, 2017. © 2017 American Institute of Chemical Engineers.

  14. Fournier's Gangrene due to Masturbation in an Otherwise Healthy Male.

    Science.gov (United States)

    Heiner, Jason D; Eng, Katisha D; Bialowas, Todd A; Devita, Diane

    2012-01-01

    Fournier's gangrene is a rare and often fulminant necrotizing fasciitis of the perineum and genital region frequently due to a synergistic polymicrobial infection. This truly emergent condition is typically seen in elderly, diabetic, or otherwise immune-compromised individuals. Here, we report an unusual case of Fournier's gangrene due to excessive masturbation in an otherwise healthy 29-year-old male who presented to the emergency department complaining of two days of fever, vomiting, and diffuse myalgias. Upon further questioning, he also endorsed severe scrotal pain and swelling and frequent masturbation with soap as a lubricant resulting in recurrent penile erythema and minor skin abrasions. Examination of the patient's perineum was consistent with Fournier's gangrene and included significant erythema, edema, and calor of the penis and scrotum with a large malodorous eschar. He was given intravenous antibiotics and immunoglobulin and promptly underwent three surgical debridements of the scrotum and penis with split-thickness skin grafting. Complications from excessive masturbation are exceedingly rare, but as this case illustrates, they can be life threatening.

  15. Fournier's Gangrene due to Masturbation in an Otherwise Healthy Male

    Directory of Open Access Journals (Sweden)

    Jason D. Heiner

    2012-01-01

    Full Text Available Fournier's gangrene is a rare and often fulminant necrotizing fasciitis of the perineum and genital region frequently due to a synergistic polymicrobial infection. This truly emergent condition is typically seen in elderly, diabetic, or otherwise immune-compromised individuals. Here, we report an unusual case of Fournier's gangrene due to excessive masturbation in an otherwise healthy 29-year-old male who presented to the emergency department complaining of two days of fever, vomiting, and diffuse myalgias. Upon further questioning, he also endorsed severe scrotal pain and swelling and frequent masturbation with soap as a lubricant resulting in recurrent penile erythema and minor skin abrasions. Examination of the patient's perineum was consistent with Fournier's gangrene and included significant erythema, edema, and calor of the penis and scrotum with a large malodorous eschar. He was given intravenous antibiotics and immunoglobulin and promptly underwent three surgical debridements of the scrotum and penis with split-thickness skin grafting. Complications from excessive masturbation are exceedingly rare, but as this case illustrates, they can be life threatening.

  16. Partial drift volume due to a self-propelled swimmer

    Science.gov (United States)

    Chisholm, Nicholas G.; Khair, Aditya S.

    2018-01-01

    We assess the ability of a self-propelled swimmer to displace a volume of fluid that is large compared to its own volume via the mechanism of partial drift. The swimmer performs rectilinear locomotion in an incompressible, unbounded Newtonian fluid. The partial drift volume D is the volume of fluid enclosed between the initial and final profiles of an initially flat circular disk of marked fluid elements; the disk is initially aligned perpendicular to the direction of locomotion and subsequently distorted due to the passage of the swimmer, which travels a finite distance. To focus on the possibility of large-scale drift, we model the swimmer simply as a force dipole aligned with the swimming direction. At zero Reynolds number (Re =0 ), we demonstrate that D grows without limit as the radius of the marked fluid disk h is made large, indicating that a swimmer at Re =0 can generate a partial drift volume much larger than its own volume. Next, we consider a steady swimmer at small Re , which is modeled as the force-dipole solution to Oseen's equation. Here, we find that D no longer diverges with h , which is due to inertial screening of viscous forces, and is effectively proportional to the magnitude of the force dipole exerted by the swimmer. The validity of this result is extended to Re ≥O (1 ) —the realm of intermediate-Re swimmers such as copepods—by taking advantage of the fact that, in this case, the flow is also described by Oseen's equations at distances much larger than the characteristic linear dimension of the swimmer. Next, we utilize an integral momentum balance to demonstrate that our analysis for a steady inertial swimmer also holds, in a time-averaged sense, for an unsteady swimmer that does not experience a net acceleration over a stroke cycle. Finally, we use experimental data to estimate D for a few real swimmers. Interestingly, we find that D depends heavily on the kinematics of swimming, and, in certain cases, D can be significantly greater

  17. Problems due to icing of overhead lines - Part II

    International Nuclear Information System (INIS)

    Havard, D.G.; Pon, C.J.; Krishnasamy, S.G.

    1985-01-01

    A companion paper describes uncertainties in overhead line design due to the variability of ice and wind loads. This paper reviews two other effects due to icing; conductor galloping and torsional instability, which require further study. (author)

  18. 77 FR 13046 - Customer Due Diligence Requirements for Financial Institutions

    Science.gov (United States)

    2012-03-05

    ... Customer Due Diligence Requirements for Financial Institutions AGENCY: Financial Crimes Enforcement Network... customer due diligence (CDD) regulation that would codify, clarify, consolidate, and strengthen existing... particular regarding issues related to identification and verification of customers as discussed in Section...

  19. Determination of Parameter Estimation Errors Due to Noise and Undermodelling

    DEFF Research Database (Denmark)

    Knudsen, Morten

    1996-01-01

    A simple method for determination of the estimation error of physical parameters due to noise and undermodelling is developed.......A simple method for determination of the estimation error of physical parameters due to noise and undermodelling is developed....

  20. Unexpected guest: Atrial fibrillation due to electrical shock

    Directory of Open Access Journals (Sweden)

    Mehmet Zihni Bilik

    2016-03-01

    Full Text Available Cardiac arrhythmias due to electrical injuries are rare among emergency service admittances. A 35 year-old female patient was admitted to emergency service with palpitation after electrical injury as a result of contact with a domestic low-voltage source. Electrocardiography (ECG showed atrial fibrillation with rapid ventricular response. Transthoracic echocardiography findings were normal. Atrial fibrillation spontaneously converted to normal sinus rhythm after rate limiting treatment with beta-blocker. The patient was discharged without any complication on the third day of hospitalization. Although cardiac arrhythmias rarely occur after electrical injury, cardiac monitoring is recommended for all patients with documented rhythm disorder, loss of consciousness, or abnormal ECG at admission.

  1. False aneurysm of ascending aorta due to pericardial mesothelioma†

    Science.gov (United States)

    Uspenskiy, Vladimir; Lavreshin, Alexei; Osadchii, Alexei; Gordeev, Michael

    2012-01-01

    Ascending aortic false aneurysm is a rare but serious complication of pericardial mesothelioma. We report a case of ascending aortic pseudoaneurysm due to spindle cell pericardial mesothelioma. In this case, the first symptoms of the disease appeared 18 months before surgery. The final diagnosis was determined only when severe late complications occurred. Palliative tumour excision, aortoplasty and aortic valve prosthesis were performed with subsequent adjuvant chemotherapy. Over 10 months after surgery, the patient is alive and a significant reduction of the tumour mass has been achieved. This case demonstrates that timely lifetime diagnosis of malignant pericardial tumour remains very difficult and effective adjuvant chemotherapy is needed to improve the results of surgery. PMID:22593561

  2. Moisture Risk in Unvented Attics Due to Air Leakage Paths

    Energy Technology Data Exchange (ETDEWEB)

    Prahl, D. [IBACOS, Inc., Pittsburgh, PA (United States); Shaffer, M. [IBACOS, Inc., Pittsburgh, PA (United States)

    2014-11-01

    IBACOS completed an initial analysis of moisture damage potential in an unvented attic insulated with closed-cell spray polyurethane foam. To complete this analysis, the research team collected field data, used computational fluid dynamics to quantify the airflow rates through individual airflow (crack) paths, simulated hourly flow rates through the leakage paths with CONTAM software, correlated the CONTAM flow rates with indoor humidity ratios from Building Energy Optimization software, and used Wärme und Feuchte instationär Pro two-dimensional modeling to determine the moisture content of the building materials surrounding the cracks. Given the number of simplifying assumptions and numerical models associated with this analysis, the results indicate that localized damage due to high moisture content of the roof sheathing is possible under very low airflow rates. Reducing the number of assumptions and approximations through field studies and laboratory experiments would be valuable to understand the real-world moisture damage potential in unvented attics.

  3. Moisture Risk in Unvented Attics Due to Air Leakage Paths

    Energy Technology Data Exchange (ETDEWEB)

    Prahl, D.; Shaffer, M.

    2014-11-01

    IBACOS completed an initial analysis of moisture damage potential in an unvented attic insulated with closed-cell spray polyurethane foam. To complete this analysis, the research team collected field data, used computational fluid dynamics to quantify the airflow rates through individual airflow (crack) paths, simulated hourly flow rates through the leakage paths with CONTAM software, correlated the CONTAM flow rates with indoor humidity ratios from Building Energy Optimization software, and used Warme und Feuchte instationar Pro two-dimensional modeling to determine the moisture content of the building materials surrounding the cracks. Given the number of simplifying assumptions and numerical models associated with this analysis, the results indicate that localized damage due to high moisture content of the roof sheathing is possible under very low airflow rates. Reducing the number of assumptions and approximations through field studies and laboratory experiments would be valuable to understand the real-world moisture damage potential in unvented attics.

  4. Nonlinear heat and particle transport due to collisional drift waves

    Energy Technology Data Exchange (ETDEWEB)

    Nishi-Kawa, K.I.; Hatori, T.; Terashima, Y.

    1978-07-01

    A nonlinear analysis of collisional drift instability is developed in a slab model based on the two fluid equations, where inhomogeneities in electron and ion temperatures and unperturbed current are included in addition to ion inertia, finite ion gyroradius, and viscosity. A systematic expansion is introduced by taking epsilon=vertical-barkappavertical-barl as a smallness parameter, where kappa is the degree of density gradient and l is the linear scale of the slab along the density gradient. The nonlinear development of the drift wave near marginal stability is studied on the basis of the model equations. A new feature, hard excitation, has been found, which is due to the effects of the nonlinear frequency shift and the electron temperature gradient. The saturation amplitude is calculated, and the expressions for wave-associated particle and heat fluxes are obtained. A comparison of the expressions with the experimental results of a stellerator device is also made.

  5. Voltage variation due to solar photovoltaic in distribution network

    International Nuclear Information System (INIS)

    Azad, H I; Ramachandaramurthy, V K; Maleki, Hesamaldin

    2013-01-01

    Grid integration of solar photovoltaic (PV) plant offers reduction in greenhouse emissions and independence from fossil fuels for power generation. The integration of such forms of power generation also brings with it a variety of policy and technical issues. One of the technical issues is the variation in grid voltages in the presence of solar photovoltaic (PV) plant, resulting in degradation of power quality. In this paper, the application of a dq current controller to limit the voltage variation at the point of common coupling (PCC) due to a 2 MW solar photovoltaic (PV) plant will be discussed. The controller's goal is to ensure that the voltage variation meets the momentary voltage change limits specified in TNB's Technical Guidebook for the connection of distributed generation. The proposed dq current controller is shown to be able to limit the voltage variation.

  6. Pancreatic Abscess in a cat due to Staphylococcus aureus infection.

    Science.gov (United States)

    Nemoto, Yuki; Haraguchi, Tomoya; Shimokawa Miyama, Takako; Kobayashi, Kosuke; Hama, Kaori; Kurogouchi, Yosuke; Fujiki, Noriyuki; Baba, Kenji; Okuda, Masaru; Mizuno, Takuya

    2017-07-07

    A 16-year-old spayed female American Shorthair cat was presented with lethargy, anorexia, and wamble. Physical and blood examination did not reveal any remarkable findings. Abdominal ultrasonography identified the presence of a localized anechoic structure with a thick wall in contact with the small intestine and adjacent to the liver. Ultrasound-guided fine-needle aspiration of the structure revealed fluid containing numerous cocci and neutrophils. Two days after antibiotic treatment, exploratory laparotomy was performed and the content of the structure was removed before multiple lavages. The pathological and bacteriological examination results supported a confirmatory diagnosis of pancreatic abscess due to Staphylococcus aureus infection, making this the first such report in a cat. The cat remained healthy thereafter with no disease recurrence.

  7. Evidence Report: Risk of Performance Errors Due to Training Deficiencies

    Science.gov (United States)

    Barshi, Immanuel

    2012-01-01

    The Risk of Performance Errors Due to Training Deficiencies is identified by the National Aeronautics and Space Administration (NASA) Human Research Program (HRP) as a recognized risk to human health and performance in space. The HRP Program Requirements Document (PRD) defines these risks. This Evidence Report provides a summary of the evidence that has been used to identify and characterize this risk. Given that training content, timing, intervals, and delivery methods must support crew task performance, and given that training paradigms will be different for long-duration missions with increased crew autonomy, there is a risk that operators will lack the skills or knowledge necessary to complete critical tasks, resulting in flight and ground crew errors and inefficiencies, failed mission and program objectives, and an increase in crew injuries.

  8. Radiation by solitons due to higher-order dispersion

    DEFF Research Database (Denmark)

    Karpman, V.I.

    1993-01-01

    We consider the Korteweg-de Vries (KdV) and nonlinear Schrodinger (NS) equations with higher-order derivative terms describing dispersive corrections. Conditions of existence of stationary and radiating solitons of the fifth-order KdV equation are obtained. An asymptotic time-dependent solution...... to the latter equation, describing the soliton radiation, is found. The radiation train may be in front as well as behind the soliton, depending on the sign of dispersion. The change rate of the soliton due to the radiation is calculated. A modification of the WKB method, that permits one to describe...... in a simple and general way the radiation of KdV and NS, as well as other types. of solitons, is developed. From the WKB approach it follows that the soliton radiation is a result of a tunneling transformation of the non-linearly self-trapped wave into the free-propagating radiation....

  9. Recurrent Aspiration Pneumonia due to Anterior Cervical Osteophyte

    Directory of Open Access Journals (Sweden)

    Jae Jun Lee

    2017-02-01

    Full Text Available A 74-year-old man presented with recurrent vomiting and aspiration pneumonia in the left lower lobe. He entered the intensive care unit to manage the pneumonia and septic shock. Although a percutaneous endoscopic gastrostomy tube was implanted for recurrent vomiting, vomiting and aspiration recurred frequently during admission. Subsequently, he complained of neck pain when in an upright position. A videofluoroscopic swallowing study showed compression of the esophagus by cervical osteophytes and tracheal aspiration caused by an abnormality at the laryngeal inlet. Cervical spine X-rays and computed tomography showed anterior cervical osteophytes at the C3-6 levels. Surgical decompression was scheduled, but was cancelled due to his frailty. Unfortunately, further recurrent vomiting and aspiration resulted in respiratory arrest leading to hypoxic brain damage and death. Physicians should consider cervical spine disease, such as diffuse skeletal hyperostosis as an uncommon cause of recurrent aspiration pneumonia.

  10. Ion heating due to rotation and collision in magnetized plasma

    International Nuclear Information System (INIS)

    Anderegg, F.; Stern, R.A.; Skiff, F.; Hammel, B.A.; Tran, M.Q.; Paris, P.J.; Kohler, P.

    1986-01-01

    The E x B rotation and associated collisional ion heating of noble-gas magnetized plasmas are investigated with high resolution by means of laser-induced fluorescence and electrical probes. Plasma rotation results from a radial potential gradient which can be controlled by biasing of the discharge electrodes. The time and space evolution of the potential, the rotation velocity v/sub t//sub h//sub e//sub t//sub a/, and the ion perpendicular temperature indicate that heating is due to the randomization of v/sub t//sub h//sub e//sub t//sub a/ by ion-neutral collisions, and leads to temperature increases as high as a factor of 50 over initial values

  11. Chronic pneumonia due to Klebsiella oxytoca mimicking pulmonary tuberculosis.

    Science.gov (United States)

    Gera, Kamal; Roshan, Rahul; Varma-Basil, Mandira; Shah, Ashok

    2015-01-01

    Klebsiella species infrequently cause acute community acquired pneumonia (CAP). The chronic form of the disease caused by K. pneumoniae (Friedlander's bacillus) was occasionally seen in the pre-antibiotic era. K. oxytoca is a singularly uncommon cause of CAP. The chronic form of the disease caused by K. oxytoca has been documented only once before. A 50-year-old immunocompetent male smoker presented with haemoptysis for 12 months. Imaging demonstrated a cavitary lesion in the right upper lobe with emphysematous changes. Sputum stains and cultures for Mycobacterium tuberculosis were negative. However, three sputum samples for aerobic culture as well as bronchial aspirate cultured pure growth of K. oxytoca. A diagnosis of chronic pneumonia due to K. oxytoca was established and with appropriate therapy, the patient was largely asymptomatic. The remarkable clinical and radiological similarity to pulmonary tuberculosis can result in patients with chronic Klebsiella pneumonia erroneously receiving anti-tuberculous therapy.

  12. Radiation dose distributions due to sudden ejection of cobalt device.

    Science.gov (United States)

    Abdelhady, Amr

    2016-09-01

    The evaluation of the radiation dose during accident in a nuclear reactor is of great concern from the viewpoint of safety. One of important accident must be analyzed and may be occurred in open pool type reactor is the rejection of cobalt device. The study is evaluating the dose rate levels resulting from upset withdrawal of co device especially the radiation dose received by the operator in the control room. Study of indirect radiation exposure to the environment due to skyshine effect is also taken into consideration in order to evaluate the radiation dose levels around the reactor during the ejection trip. Microshield, SHLDUTIL, and MCSky codes were used in this study to calculate the radiation dose profiles during cobalt device ejection trip inside and outside the reactor building. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. In Brief: Refugee numbers could increase due to climate change

    Science.gov (United States)

    Zielinski, Sarah

    2007-05-01

    Climate change could push the number of refugees globally to more than one billion by 2050, according to a new report from the British charity Christian Aid. Currently, there are about 155 million `internally displaced persons' worldwide, driven from their homes due to conflict, ethnic persecution, or natural disasters. The addition of climate change and growing population numbers could exacerbate these ongoing problems. In the report, Mali is presented as a case study where ongoing climate change is forcing farmers to find other ways to feed their families; one result is an increased number of people attempting to migrate to Europe. The report calls on rich nations to devote US$100 billion each year to help poor people adapt to changing weather patterns. The report, ``Human tide: the real migration crisis,'' is available at http://www.christian-aid.org.uk/indepth/705caweekreport/

  14. Elevated plasma creatinine due to creatine ethyl ester use.

    Science.gov (United States)

    Velema, M S; de Ronde, W

    2011-02-01

    Creatine is a nutritional supplement widely used in sport, physical fitness training and bodybuilding. It is claimed to enhance performance. We describe a case in which serum creatinine is elevated due to the use of creatine ethyl esther. One week after withdrawal, the plasma creatinine had normalised. There are two types of creatine products available: creatine ethyl esther (CEE) and creatine monohydrate (CM). Plasma creatinine is not elevated in all creatine-using subjects. CEE , but not CM, is converted into creatinine in the gastrointestinal tract. As a result the use of CEE may be associated with elevated plasma creatinine levels. Since plasma creatinine is a widely used marker for renal function, the use of CEE may lead to a false assumption of renal failure.

  15. Ionizing Radiation Dose Due to the Use of Agricultural Fertilizers

    International Nuclear Information System (INIS)

    Umisedo, Nancy K.; Okuno, Emico; Medina, Nilberto H.; Colacioppo, Sergio; Hiodo, Francisco Y.

    2008-01-01

    The transference of radionuclides from the fertilizers to/and from soils to the foodstuffs can represent an increment in the internal dose when the vegetables are consumed by the human beings. This work evaluates the contribution of fertilizers to the increase of radiation level in the environment and of dose to the people. Samples of fertilizers, soils and vegetables produced in farms located in the neighbourhood of Sao Paulo city in the State of Sao Paulo, Brazil were analysed through gamma spectroscopy. The values of specific activity of 40 K, 238 U and 232 Th show that there is no significant transference of natural radionuclides from fertilizers to the final product of the food chain. The annual committed effective dose due to the ingestion of 40 K contained in the group of consumed vegetables analysed in this work resulted in the very low value of 0.882 μSv

  16. Occupational dose due to neutrons in medical linear accelerators

    International Nuclear Information System (INIS)

    Larcher, Ana M.; Bonet Duran, Stella M.; Lerner, Ana M.

    2000-01-01

    This paper describes a semi-empirical method to calculate the occupational dose due to neutrons and capture gamma rays in medical linear accelerators. It compares theoretical dose values with measurements performed in several 15 MeV medical accelerators installed in the country. Good agreement has been found between calculations made using the model and dose measurements, except for those accelerator rooms in which the maze length was shorter than the postulated tenth value distance. For those cases the model seems to overestimate neutron dose. The results demonstrate that the semi-empirical model is a good tool for quick and conservative shielding calculations for radiation protection purposes. Nevertheless, it is necessary to continue with the measurements in order to perform a more accurate validation of the model. (author)

  17. Impact of hydrotherapy on skin blood flow: How much is due to moisture and how much is due to heat?

    Science.gov (United States)

    Petrofsky, Jerrold; Gunda, Shashi; Raju, Chinna; Bains, Gurinder S; Bogseth, Michael C; Focil, Nicholas; Sirichotiratana, Melissa; Hashemi, Vahideh; Vallabhaneni, Pratima; Kim, Yumi; Madani, Piyush; Coords, Heather; McClurg, Maureen; Lohman, Everett

    2010-02-01

    Hydrotherapy and whirlpool are used to increase skin blood flow and warm tissue. However, recent evidence seems to show that part of the increase in skin blood flow is not due to the warmth itself but due to the moisture content of the heat. Therefore, two series of experiments were accomplished on 10 subjects with an average age of 24.2 +/- 9.7 years and free of diabetes and cardiovascular disease. Subjects sat in a 37 degrees C hydrotherapy pool under two conditions: one in which a thin membrane protecting their skin from moisture while their arm was submerged in water and the second where their arm was allowed to be exposed to the water for 15 minutes. During this period of time, skin and body temperature were measured as well as skin blood flow by a Laser Doppler Imager. The results of the experiments showed that the vapor barrier blocked any change in skin moisture content during submersion in water, and while skin temperature was the same as during exposure to the water, the blood flow with the arm exposed to water increased from 101.1 +/- 10.4 flux to 224.9 +/- 18.2 flux, whereas blood flow increased to only 118.7 +/- 11.4 flux if the moisture of the water was blocked. Thus, a substantial portion of the increase in skin blood flow associated with warm water therapy is probably associated with moisturizing of the skin rather than the heat itself.

  18. Warming Can Boost Denitrification Disproportionately Due to Altered Oxygen Dynamics

    Science.gov (United States)

    Veraart, Annelies J.; de Klein, Jeroen J. M.; Scheffer, Marten

    2011-01-01

    Background Global warming and the alteration of the global nitrogen cycle are major anthropogenic threats to the environment. Denitrification, the biological conversion of nitrate to gaseous nitrogen, removes a substantial fraction of the nitrogen from aquatic ecosystems, and can therefore help to reduce eutrophication effects. However, potential responses of denitrification to warming are poorly understood. Although several studies have reported increased denitrification rates with rising temperature, the impact of temperature on denitrification seems to vary widely between systems. Methodology/Principal Findings We explored the effects of warming on denitrification rates using microcosm experiments, field measurements and a simple model approach. Our results suggest that a three degree temperature rise will double denitrification rates. By performing experiments at fixed oxygen concentrations as well as with oxygen concentrations varying freely with temperature, we demonstrate that this strong temperature dependence of denitrification can be explained by a systematic decrease of oxygen concentrations with rising temperature. Warming decreases oxygen concentrations due to reduced solubility, and more importantly, because respiration rates rise more steeply with temperature than photosynthesis. Conclusions/Significance Our results show that denitrification rates in aquatic ecosystems are strongly temperature dependent, and that this is amplified by the temperature dependencies of photosynthesis and respiration. Our results illustrate the broader phenomenon that coupling of temperature dependent reactions may in some situations strongly alter overall effects of temperature on ecological processes. PMID:21483809

  19. Deep brain stimulation in addiction due to psychoactive substance use.

    Science.gov (United States)

    Kuhn, Jens; Bührle, Christian P; Lenartz, Doris; Sturm, Volker

    2013-01-01

    Addiction is one of the most challenging health problems. It is associated with enormous individual distress and tremendous socioeconomic consequences. Unfortunately, its underlying mechanisms are not fully understood, and pharmacological, psychological, or social interventions often fail to achieve long-lasting remission. Next to genetic, social, and contextual factors, a substance-induced dysfunction of the brain's reward system is considered a decisive factor for the establishment and maintenance of addiction. Due to its successful application and approval for several neurological disorders, deep brain stimulation (DBS) is known as a powerful tool for modulating dysregulated networks and has also been considered for substance addiction. Initial promising case reports of DBS in alcohol and heroin addiction in humans have recently been published. Likewise, results from animal studies mimicking different kinds of substance addiction point in a similar direction. The objective of this review is to provide an overview of the published results on DBS in addiction, and to discuss whether these preliminary results justify further research, given the novelty of this treatment approach. © 2013 Elsevier B.V. All rights reserved.

  20. Warming can boost denitrification disproportionately due to altered oxygen dynamics.

    Directory of Open Access Journals (Sweden)

    Annelies J Veraart

    Full Text Available BACKGROUND: Global warming and the alteration of the global nitrogen cycle are major anthropogenic threats to the environment. Denitrification, the biological conversion of nitrate to gaseous nitrogen, removes a substantial fraction of the nitrogen from aquatic ecosystems, and can therefore help to reduce eutrophication effects. However, potential responses of denitrification to warming are poorly understood. Although several studies have reported increased denitrification rates with rising temperature, the impact of temperature on denitrification seems to vary widely between systems. METHODOLOGY/PRINCIPAL FINDINGS: We explored the effects of warming on denitrification rates using microcosm experiments, field measurements and a simple model approach. Our results suggest that a three degree temperature rise will double denitrification rates. By performing experiments at fixed oxygen concentrations as well as with oxygen concentrations varying freely with temperature, we demonstrate that this strong temperature dependence of denitrification can be explained by a systematic decrease of oxygen concentrations with rising temperature. Warming decreases oxygen concentrations due to reduced solubility, and more importantly, because respiration rates rise more steeply with temperature than photosynthesis. CONCLUSIONS/SIGNIFICANCE: Our results show that denitrification rates in aquatic ecosystems are strongly temperature dependent, and that this is amplified by the temperature dependencies of photosynthesis and respiration. Our results illustrate the broader phenomenon that coupling of temperature dependent reactions may in some situations strongly alter overall effects of temperature on ecological processes.

  1. Replication of genetic associations as pseudoreplication due to shared genealogy.

    Science.gov (United States)

    Rosenberg, Noah A; Vanliere, Jenna M

    2009-09-01

    The genotypes of individuals in replicate genetic association studies have some level of correlation due to shared descent in the complete pedigree of all living humans. As a result of this genealogical sharing, replicate studies that search for genotype-phenotype associations using linkage disequilibrium between marker loci and disease-susceptibility loci can be considered as "pseudoreplicates" rather than true replicates. We examine the size of the pseudoreplication effect in association studies simulated from evolutionary models of the history of a population, evaluating the excess probability that both of a pair of studies detect a disease association compared to the probability expected under the assumption that the two studies are independent. Each of nine combinations of a demographic model and a penetrance model leads to a detectable pseudoreplication effect, suggesting that the degree of support that can be attributed to a replicated genetic association result is less than that which can be attributed to a replicated result in a context of true independence.

  2. Anton's syndrome due to cerebrovascular disease: a case report

    Directory of Open Access Journals (Sweden)

    Maddula Mohana

    2009-09-01

    Full Text Available Abstract Introduction Anton's syndrome describes the condition in which patients deny their blindness despite objective evidence of visual loss, and moreover confabulate to support their stance. It is a rare extension of cortical blindness in which, in addition to the injury to the occipital cortex, other cortical centres are also affected, with patients typically behaving as if they were sighted. Case presentation We present a case report of an 83-year-old white woman with cortical blindness as a result of bilateral occipital lobe infarcts. Despite her obvious blindness, illustrated by her walking into objects, the patient expressed denial of visual loss and demonstrated confabulation in her accounts of her surroundings, consistent with a diagnosis of Anton's syndrome. Conclusions A suspicion of cortical blindness and Anton's syndrome should be considered in patients with atypical visual loss and evidence of occipital lobe injury. Cerebrovascular disease is the most common cause of Anton's syndrome, as in our patient. However, any condition that may result in cortical blindness can potentially lead to Anton's syndrome. Recovery of visual function will depend on the underlying aetiology, with cases due to occipital lobe infarction after cerebrovascular events being less likely to result in complete recovery. Management in these circumstances should accordingly focus on secondary prevention and rehabilitation.

  3. Apparent losses due to domestic water meter under-registration in ...

    African Journals Online (AJOL)

    By combining these results with the average age of meters in South Africa, estimated from the National Water Demand Archive, it was possible to estimate the average meter under-registration due to meter aging. The study concluded that apparent losses due to water meter under-registration are around 5% of consumption ...

  4. Risks to offshore installations in Europe due to natural hazards

    Science.gov (United States)

    Necci, Amos; Krausmann, Elisabeth

    2017-04-01

    Natural hazards, such as storms, earthquakes, or lightning are a major threat to industry. In particular, chemical plants, storage facilities, pipelines, and offshore oil and gas facilities are vulnerable to natural events which can cause hazardous materials releases and thereby endanger workers, the population and the environment. These technological accidents are commonly referred to as Natech accidents. Recent events have increased concerns about safety in the offshore oil and gas sector, and the need for improving knowledge on the matter has become evident. With those premises, we analyzed accidents, near misses and accident precursors at offshore facilities in Europe caused by natural events using both a statistical and a qualitative approach. For this purpose, we screened the World Offshore Accident Database (WOAD) to identify all incidents that featured natural events as causes or aggravating factors. A dataset of 1,085 global Natech events was built for the statistical analysis. Among those, a subset composed of 303 European records was selected. The results of the analysis showed that offshore Natech events in Europe are frequent; they resulted, however, in low consequences. The main threat to offshore facilities resulted from bad weather, such as strong winds and heavy seas. Storms can put intense loads on the structural parts of offshore installations, eventually exceeding design resistance specifications. Several incidents triggered by lightning strikes and earthquakes were also recorded. Substantial differences in terms of vulnerability, damage modality and consequences emerged between fixed and floating offshore structures. The main damage mode for floating structures was the failure of station keeping systems due to the rupture of mooring or anchors, mainly caused by adverse meteorological conditions. Most of the incidents at fixed offshore structures in Europe involved falling loads for both metal jacket and concrete base platforms due to storms. In

  5. Days Out of Role Due to Mental and Physical Conditions: Results from the Singapore Mental Health Study.

    Directory of Open Access Journals (Sweden)

    Edimansyah Abdin

    Full Text Available The aim of the current study was to evaluate the relative contributions of mental and physical conditions to days out of role among adults aged 18 years and above in Singapore.The Singapore Mental Health Study was a cross-sectional epidemiological survey of a nationally representative sample of residents aged 18 years or older. Diagnosis of mental disorders was established using the Composite International Diagnostic Interview; while chronic physical conditions were established using a checklist. Days out of role were assessed using a WHO Disability Assessment Schedule item. Multivariate regression analyses were used to estimate individual-level and societal-level effects of disorders.Overall, 8.7% of respondents reported at least one day out of role, with a mean of 5.8 days. The most disabling conditions at the individual level were cancer (118.9 additional days, cardiovascular diseases (93.5, and bipolar disorder (71.0. At the societal level, cardiovascular diseases contributed the highest population attributable risk proportion (45%, followed by cancer (39.3%, and hypertension (13.5%.Mental and physical conditions are linked to significant losses in productivity for society as well as role disability for individuals, underscoring the need to enhance prevention and intervention efforts to increase overall productivity and improve individual functioning.

  6. Days out of role due to common physical and mental conditions: results from the WHO World Mental Health surveys.

    Science.gov (United States)

    Alonso, J; Petukhova, M; Vilagut, G; Chatterji, S; Heeringa, S; Üstün, T B; Alhamzawi, A O; Viana, M C; Angermeyer, M; Bromet, E; Bruffaerts, R; de Girolamo, G; Florescu, S; Gureje, O; Haro, J M; Hinkov, H; Hu, C-y; Karam, E G; Kovess, V; Levinson, D; Medina-Mora, M E; Nakamura, Y; Ormel, J; Posada-Villa, J; Sagar, R; Scott, K M; Tsang, A; Williams, D R; Kessler, R C

    2011-12-01

    Days out of role because of health problems are a major source of lost human capital. We examined the relative importance of commonly occurring physical and mental disorders in accounting for days out of role in 24 countries that participated in the World Health Organization (WHO) World Mental Health (WMH) surveys. Face-to-face interviews were carried out with 62 971 respondents (72.0% pooled response rate). Presence of ten chronic physical disorders and nine mental disorders was assessed for each respondent along with information about the number of days in the past month each respondent reported being totally unable to work or carry out their other normal daily activities because of problems with either physical or mental health. Multiple regression analysis was used to estimate associations of specific conditions and comorbidities with days out of role, controlling by basic socio-demographics (age, gender, employment status and country). Overall, 12.8% of respondents had some day totally out of role, with a median of 51.1 a year. The strongest individual-level effects (days out of role per year) were associated with neurological disorders (17.4), bipolar disorder (17.3) and post-traumatic stress disorder (15.2). The strongest population-level effect was associated with pain conditions, which accounted for 21.5% of all days out of role (population attributable risk proportion). The 19 conditions accounted for 62.2% of all days out of role. Common health conditions, including mental disorders, make up a large proportion of the number of days out of role across a wide range of countries and should be addressed to substantially increase overall productivity.

  7. [Maternal deaths due to amniotic fluid embolism. Results from the French confidential enquiry into maternal deaths, 2010-2012].

    Science.gov (United States)

    Morau, E; Proust, A; Ducloy, J-C

    2017-12-01

    Amniotic fluid embolism (AFE) is an unpredictable, dreadful complication of pregnancy or childbirth. EA typically includes in the same lapse of time respiratory, haemodynamic, neurological and hemorrhagic symptoms (from early and severe coagulopathy). Immediate supportive treatment by a multidisciplinary team is the cornerstone of the management. Between 2010 an 2012 in France, 24 deaths were related to AFE giving a maternal mortality ratio of 1/100,000 live births (CI 95% 0.6-1.4). AFE ranks as the second leading cause of direct maternal death. Eight cases over 23 were classified as having some degree of substandard care. Substandard care included delays in performing aggressive surgical treatment or delays in the diagnosis and the treatment of the coagulopathy. Learning points focus on the importance to pay attention on premonitory symptoms, to early assess the clotting status and to train in multidisciplinary team. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  8. [Maternal deaths due to hypertensive disorders. Results from the French confidential enquiry into maternal deaths, 2010-2012].

    Science.gov (United States)

    Dreyfus, M; Weber, P; Zieleskiewicz, L

    2017-12-01

    Between 2010 and 2012, the rate of maternal death caused by hypertensive disorders (0,5/100,000 living birth) was reduced by 50% compared to the 2007-2009 period. Hypertensive disorders were responsible from 5% of maternal deaths and from 10% of direct maternal mortality. Eleven deaths happened during the postpartum period but 9 hypertensive complications began before delivery. Seventy percent of these deaths seem to be avoidable. The main causes of suboptimal management were: unappropriated or insufficient obstetrical and anesthetic treatments, undiagnosed HELLP syndrome and subcapsular liver hematoma, delayed treatment. The analysis of these maternal deaths gave the opportunity to stress some major lessons to optimize medical management in case of hypertensive diseases during pregnancy: abdominal symptoms during third trimester of pregnancy lead to search hypertensive disorders; HELLP syndrome with severe anemia indicate to carry out abdominal ultrasound. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  9. Low-grade neuroinflammation due to chronic sleep deprivation results in anxiety and learning and memory impairments.

    Science.gov (United States)

    Manchanda, Shaffi; Singh, Harpal; Kaur, Taranjeet; Kaur, Gurcharan

    2018-03-16

    Chronic sleep loss/fragmentation prevalent in the current 24/7 society is associated with irreversible consequences on health and overall wellbeing. Various studies have well documented the ill effects of acute sleep loss on cognitive functions of individuals; however, the underlying mechanism behind the chronic sleep loss is yet to be explored. The present study was aimed to investigate whether chronic sleep deprivation (CSD) triggers anxiety-like behaviour and memory decline in male Wistar rats. Rats were sleep deprived by placing them over slowly rotating drum (2 rpm) for 18 h (between 4 pm and 10 am) followed by 6 h of recovery sleep for 21 consecutive days. Post CSD regimen, rats were subjected to behavioural tests such as elevated plus maze (EPM), Novel Object Recognition (NOR) and Rotarod performance test and then sacrificed to remove brain for further molecular studies. The study demonstrated that CSD rats showed anxiogenic behaviour along with recognition memory decline compared to control rats. CSD rats further showed elevated levels of inflammatory cytokines (TNFα, IL-1β) along with activation of NFκB and AP1 transcription factors in hippocampus and piriform cortex (PC) regions of brain. These observations were also accompanied by enhanced expression of GFAP and Iba1 in the two brain regions. The data suggest that CSD triggered low-grade neuroinflammation which caused anxiogenic response and recognition memory impairment. The study provides preliminary leads to further explore the role of astrocytes/microglial cells and inflammatory cytokines in mediating these neurobehavioural consequences of chronic sleep loss and to develop effective interventions to combat them.

  10. [Results of a national survey on the antibiotic therapy of neonatal bacterial infection due to materno-fetal contamination].

    Science.gov (United States)

    Bourrillon, A; Laik, P

    1986-03-01

    The aim of the study was to overview the antibiotic treatments usually prescribed in the different neonatal units and NICU's for neonatal primary bacterial infections. Maternal or neonatal fever, shock, respiratory distress, leuconeutropenia, hyperfibrinemia as well as an increased level in C-Reactive Protein appeared to be the best clinical diagnosis criteria. Before isolation of the bacteria, the most frequently prescribed treatment was a combination of ampicillin and gentamicin. When no bacteria grew up, the treatment was usually discontinued after a few days. When a presumably pathogenic bacteria was found either in blood, or CSF or urine or peripheral cultures, the treatment lasted around 10 days. However, in proved meningitis, the treatment lasted around 20 days. In case of Streptococcus type B and Listeria monocytogenes, ampicillin (100-200 mg/kg/day) was often used in combination with gentamicin (3-4 mg/kg/day), in spite of the recent availability of new aminoglycosides. When the isolated E. coli was ampicillin-resistant, Cefotaxime was frequently used in combination.

  11. Hepatic specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis

    Science.gov (United States)

    Kim, Hyun-Seok; Xiao, Cuiying; Wang, Rui-Hong; Lahusen, Tyler; Xu, Xiaoling; Vassilopoulos, Athanassios; Vazquez-Ortiz, Guelaguetza; Jeong, Won-Il; Park, Ogyi; Ki, Sung Hwan; Gao, Bin; Deng, Chu-Xia

    2010-01-01

    Under various conditions mammals have the ability to maintain serum glucose concentration within a narrow range. SIRT1 plays an important role in regulating gluconeogenesis and fat metabolism; however, the underlying mechanisms remain elusive. Here we show that SIRT1 forms a complex with FOXO3a and NRF1 on the SIRT6 promoter and positively regulates expression of SIRT6, which in turn negatively regulates glycolysis, triglyceride synthesis and fat metabolism by deacetylating histone H3 lysine 9 in the promoter of many genes involved in these processes. Liver specific deletion of SIRT6 in mice causes profound alterations in gene expression, leading increased glycolysis, triglyceride synthesis, reduced β-oxidation, and fatty liver formation. Human fatty liver samples exhibited significantly lower levels of SIRT6 than normal controls. Thus, SIRT6 plays a critical role in fat metabolism, and may serve as a novel therapeutic target for treating fatty liver disease, the most common cause of liver dysfunction in humans. PMID:20816089

  12. Wandering Fish Bone: a Case of Pelvic Abscess due to Rectum Perforation Resulting from an Accidental Fish Bone Ingestion

    Directory of Open Access Journals (Sweden)

    Sirous Abbasi

    2010-09-01

    Full Text Available Fish bone is the most common foreign body that is ingested accidentally and can be caused gastrointestinal complications such as perforation, abstraction, and abscess. We describe a 75-year-old man who suffered from constipation, diarrhea, and fever and chills for 3 months. He had mild tenderness in hypogasteric region and also mild tenderness and swelling on anterior rectal wall and prostate upon clinical examination. The abdominal and pelvic sonography and CT scan findings suggested existence of abscess in the space of between bladder and rectum. The patient underwent laparotomy to drainage the pelvic abscess. The surgeon found a 6-cm fish bone which was embedded in the abscess. The presented case indicated the importance of accidental fish bone ingestion and its possible complications. In addition, the patients with abdominal pain, GI bleeding, and fever of unknown origin living in the seaside regions, the wandering fish bone as a differential diagnosis should be kept in mind.

  13. Overcurrent protection issues due to the DG connection

    Energy Technology Data Exchange (ETDEWEB)

    Gomez, J.C.; Tourn, D.H.; Amatti, J.C. [Rio Cuarto National University (IPSEP/UNRC), Cordoba (Argentina). Electric Power Systems Protection Institute], E-mail: jcgomez@ing.unrc.edu.ar

    2009-07-01

    The present energy crisis drives to carry to an extreme the use of all the available energy sources, which need to be connected to the network in their closest point. Traditional electric systems are changing their characteristics, in what concerns to structure, operation, and especially on protection methodologies. The new protection problems of the different parts of the system are explained. The solution presents positive and negative aspects that impact the utility and the customer in different ways. A revision about interconnection international standards is presented. The contributions of generators to short circuit currents is analyzed, especially the double fed generator. Philosophy changes are studied, such as: fault current bi directionality, modification of the protection reach, failures of the overcurrent coordination due to current share, etc. Solicitations to DG due to the normal unbalance of distribution systems are also studied. It is analyzed the discrepancy between the customers and utilities regarding the 'islanding operation', presenting the semi-rigid connection. The changes in the coordination methodology fusible-recloser are also studied, proposing a new methodology to check this coordination. Experimental results on 13.2 kV are presented that relate the deionization without zero current, with arc length and with 'network power to DG power ratio'. It is concluded that DG application offers technical-economic advantages so much to the utility as to the user; and that the technology for these new protection approaches is already available, requiring of investments whose justification needs of a specific analysis for each particular case. (author)

  14. A CLINICORADIOLOGICAL STUDY OF MIDDLE LOBE SYNDROME DUE TO TUBERCULOSIS

    Directory of Open Access Journals (Sweden)

    Saurabh Karmakar

    2016-09-01

    Full Text Available BACKGROUND Although pulmonary tuberculosis is a common disease in India, tuberculosis of right middle lobe is infrequent. Tuberculosis of the right middle lobe leading to chronic collapse is a cause of Right Middle Lobe syndrome. METHODS The patients attended Pulmonary Medicine Outdoor at Era’s Lucknow Medical College, Lucknow from April 2015 to March 2016. The purpose of this study is to describe the clinicoradiological features of patients of middle lobe syndrome due to tuberculosis. All patients presented with cough with or without expectoration, fever, chest pain, haemoptysis and constitutional symptoms like loss of appetite and weight. Chest X-ray PA view revealed ill-defined opacity abutting the right cardiac border. HRCT thorax was done in each case. The diagnosis of tuberculous aetiology was based on (1 History of chronic cough and fever, not responding to antibiotic therapy and constitutional symptoms, (2 A positive tuberculin test using 2 TU of PPD RT 23 and (3 Detection of acid fast bacilli by direct smear or Mycobacterium tuberculosis by polymerase chain reaction in bronchoalveolar lavage. RESULTS Out of 10 patients, 4 (40% were males and 6 (60% were females. The mean ages of the males were 55.8 years and females were 60.8 years and overall mean age was 59 years. Most of the patients were females and belonged to the middle age and old age group. ATT was started in all the patients. CONCLUSIONS Right middle lobe syndrome predominantly affects the older population and the female gender. Although tuberculosis is a common disease in India, Middle Lobe Syndrome is a very rare presentation of the disease. Due to non-specific symptoms and usually normal chest X-ray PA view in Right Middle Lobe Syndrome, we should keep a high index of suspicion to diagnose the condition.

  15. Posturography as an indicator of fatigue due to sleep deprivation.

    Science.gov (United States)

    Morad, Yair; Azaria, Bella; Avni, Isaac; Barkana, Yaniv; Zadok, David; Kohen-Raz, Reuven; Barenboim, Erez

    2007-09-01

    Fatigue is one of the main causes for accidents in transportation. This study was designed to assess the efficacy of a short objective posturographic test as an indicator of fatigue due to sleep deprivation. To assess the efficiency of a short objective posturographic test as an indicator of fatigue due to sleep deprivation. Postural control was measured using four-plate posturograhy with eyes open and eyes closed. Over a period of 26 h of sleep deprivation (from 08:00 to 10:00 the following day) 12 subjects were studied 10 times. The posturographic data were correlated with a subjective fatigue assessed by means of the Stanford Sleepiness Score. Stability and sway intensity while eyes were closed showed a statistically significant circadian pattern with a peak at early morning hours and a recovery at 10:00 the following day. When eyes were open, only changes within the medium-low frequency band (0.1-0.05 Hz), believed to be linked with vestibular function, reached statistical significance. The Subjective Feeling Scale pattern was similar to the postural parameters, but with an absence of recovery at 10:00 the following day. Excluding this point, significant correlations were found between posturography with eyes closed and this scale. Fatigue caused by sleep deprivation can be objectively assessed by a short, non-invasive, postural test. The vestibular function appears to be relatively more strongly affected by fatigue than the visual and somato-sensory sub-systems. Occlusion of vision appears to enhance the effect of fatigue on postural performance. Our results may imply that this test could be used as an efficient screening tool for detection of fatigue.

  16. Dynamic shear modulus of glycerol: Corrections due to instrument compliance

    Science.gov (United States)

    Schröter, K.; Hutcheson, S. A.; Shi, X.; Mandanici, A.; McKenna, G. B.

    2006-12-01

    A recent article by Shi et al. [J. Chem. Phys.123, 174507 (2005)] reports results from mechanical measurements on three simple inorganic glass formers: glycerol, m-toluidine, and sucrose benzoate. The experiments carried out were stress relaxation, aging, and dynamic (all in shear) using a torsional rheometer, an advanced rheometric expansion system (TA Instruments). The original force rebalance transducer (2KFRT) supplied with the system was replaced with a custom-made load cell (Sensotec) that had a capacity of 20000gcm in torque and 5000g in normal force. The replacement of the load cell was done due to the belief that the main source of compliance in this instrument was from the 2KFRT. With this assumption, the authors published their results for the three materials of interest and compared their results with the techniques of Schröter and Donth [J. Chem. Phys.113, 9101 (2000)] for the measurements on glycerol and reported important differences. These differences were disputed by one of the present authors (Schröter), and the present report shows that the results from Schröter and Donth are correct. We show that the reasons have to do with the instrument compliance being greater than originally thought by Shi et al. Here we examine the effects of platen diameter/geometry on the glycerol dynamic moduli, describe a means to correct dynamic data, present a revised comparison of the corrected data with that of Schröter and Donth, and provide a discussion of future work and conclusions.

  17. Preliminary observations of environmental damage due to the Gulf War

    International Nuclear Information System (INIS)

    El-Baz, F.

    1992-01-01

    Preparing for and conducting the Gulf War resulted in much damage to the environment of the region. The first and most visible effect is related to the damage caused by oil well fires in terms of air pollution as well as the potential damage to the petroleum reservoirs. The second detrimental effect has been caused by the oil spill in the Gulf water. Hundreds of miles of the western coastline of the Gulf are already covered with oil. Petroleum 'mats' have settled on coral reefs and have reduced Gulf water productivity. Foremost among the irreparable damages are changes to the terrain due to the digging of trenches, building walls of soil and otherwise disturbing the desert pavement in and around Kuwait. Disruption of the, usually, one-grain thick layer of pebbles on the desert floor exposes soil to wind action. Changing the contours of the normally flat land increases resistance to the wind and increases the potential of particle transport until the land is peneplained. This condition will increase the frequency and the ferocity of dust storms in the region. It will also result in the formation of new sand dunes; sand drifts already exist along roads in northern Kuwait. It is believed that the detrimental effects on the atmosphere will last for years, on the Gulf water for decades, and on the desert surface for centuries. (author). 12 refs, 1 fig

  18. Global assessment of human losses due to earthquakes

    Science.gov (United States)

    Silva, Vitor; Jaiswal, Kishor; Weatherill, Graeme; Crowley, Helen

    2014-01-01

    Current studies have demonstrated a sharp increase in human losses due to earthquakes. These alarming levels of casualties suggest the need for large-scale investment in seismic risk mitigation, which, in turn, requires an adequate understanding of the extent of the losses, and location of the most affected regions. Recent developments in global and uniform datasets such as instrumental and historical earthquake catalogues, population spatial distribution and country-based vulnerability functions, have opened an unprecedented possibility for a reliable assessment of earthquake consequences at a global scale. In this study, a uniform probabilistic seismic hazard assessment (PSHA) model was employed to derive a set of global seismic hazard curves, using the open-source software OpenQuake for seismic hazard and risk analysis. These results were combined with a collection of empirical fatality vulnerability functions and a population dataset to calculate average annual human losses at the country level. The results from this study highlight the regions/countries in the world with a higher seismic risk, and thus where risk reduction measures should be prioritized.

  19. Electromechanical coupling in piezoelectric nanobeams due to the flexoelectric effect

    Science.gov (United States)

    Zhou, Z. D.; Yang, C. P.; Su, Y. X.; Huang, R.; Lin, X. L.

    2017-09-01

    The flexoelectric effect is a coupling of polarization and strain gradient, which exists in a wide variety of materials and may lead to strong size-dependent properties at the nanoscale. Based on an extension to the classical beam model, this paper investigates the electromechanical coupling response of piezoelectric nanobeams with different electrical boundary conditions including the effect of flexoelectricity. The electric Gibbs free energy and the variational principle are used to derive the governing equations with three types of electrical boundary conditions. Closed-form solutions are obtained for static bending of cantilever beams. The results show that the normalized effective stiffness increases with decreasing beam thickness in the open circuit electrical boundary conditions with or without surface electrodes. The induced electric potential due to the flexoelectric effect is obtained under the open circuit conditions, which may be important for sensing or energy harvesting applications. An intrinsic thickness depending on the material properties is identified for the maximum induced electric potential. The present results also show that flexoelectricity has a more significant effect on the electroelastic responses than piezoelectricity at the nanoscale. Our analysis in the present study can be useful for understanding of the electromechanical coupling in nanobeams with flexoelectricity.

  20. Sinkholes Due to Groundwater Withdrawal in Tazerbo Wellfield, SE Libya.

    Science.gov (United States)

    Alfarrah, Nawal; Berhane, Gebremedhin; Hweesh, Abdelrahim; Walraevens, Kristine

    2017-07-01

    The desert of eastern Libya forms one of the most arid regions of the Sahara. The Great Man-Made River Project (GMRP) was established. It transports millions of cubic meters of water a day from desert wellfields to the coastal cities, where over 80% of the population lives. The Tazerbo Wellfield is one of the wellfields designed within the GMRP, delivering water to the eastern coast of Libya through an underground pipe network. Tazerbo Wellfield consists of 108 production wells; each well was designed to pump 100 L/s. The planned total groundwater withdrawal from all wells is 1 million m 3 /d. The deep sandstone aquifer (Nubian sandstone) is covered by a thick mudstone-siltstone aquitard and is being heavily pumped. The aquifer and fine-grained sediments of the aquitard may be compacted resulting in land subsidence as a result of high exploitation. Local sinkholes have developed in the area of Tazerbo since the start of the pumping from the wellfield in 2004. These sinkholes have been caused mainly by lowering of the piezometric heads due to the withdrawal of groundwater. In this study, a hydrogeological investigation is presented about the effect of large groundwater pumping from the Nubian sandstone aquifer in Tazerbo Wellfield, SE Libya, based on physical parameters for 108 production wells and 23 observation wells. © 2017, National Ground Water Association.

  1. Perihelic shift of planets due to the gravitational field of the charged Sun

    International Nuclear Information System (INIS)

    Teli, M.T.; Palaskar, D.

    1984-01-01

    The perihelic shift of planets due to the charged Sun is calculated. The results when compared with experimental shifts suggest that the planets Mercury, Venus and Icarus do not possess self-electromagnetic fields

  2. Cassini at Saturn Huygens results

    CERN Document Server

    Harland, David M

    2007-01-01

    "Cassini At Saturn - Huygens Results" will bring the story of the Cassini-Huygens mission and their joint exploration of the Saturnian system right up to date. Cassini is due to enter orbit around Saturn on the 1 July 2004 and the author will have 8 months of scientific data available for review, including the most spectacular images of Saturn, its rings and satellites ever obtained by a space mission. As the Cassini spacecraft approached its destination in spring 2004, the quality of the images already being returned by the spacecraft clearly demonstrate the spectacular nature of the close-range views that will be obtained. The book will contain a 16-page colour section, comprising a carefully chosen selection of the most stunning images to be released during the spacecraft's initial period of operation. The Huygens craft will be released by Cassini in December 2004 and is due to parachute through the clouds of Saturn's largest moon, Titan, in January 2005.

  3. Magnetic Generation due to Mass Difference between Charge Carriers

    OpenAIRE

    Chen, Shi; Dan, JiaKun; Chen, ZiYu; Li, JianFeng

    2013-01-01

    The possibility of spontaneous magnetization due to the "asymmetry in mass" of charge carriers in a system is investigated. Analysis shows that when the masses of positive and negative charge carriers are identical, no magnetization is predicted. However, if the masses of two species are different, spontaneous magnetic field would appear, either due to the equipartition of magnetic energy or due to fluctuations together with a feedback mechanism. The conditions for magnetization to occur are ...

  4. Intestinal Necrosis due to Giant Ovarian Cyst: A Case Report

    OpenAIRE

    Duran, Ali; Duran, Fulay Yilmaz; Cengiz, Fevzi; Duran, Ozgur

    2013-01-01

    Intestinal pathologies due to ovarian cyst are observed rarely. Although a limited number of cases in neonatal and adolescent periods have been observed, no adult case has been reported in the literature. Two mechanisms are involved in intestinal complications due to ovarian cysts: torsion due to adhesion or compression of giant ovarian mass with a diameter of 9-10 cm. We report here a terminal ileum necrosis case due to compression by an ovarian cyst with 11 × 10 × 7 cm size in an 81-year-ol...

  5. Intestinal Necrosis due to Giant Ovarian Cyst: A Case Report

    Directory of Open Access Journals (Sweden)

    Ali Duran

    2013-01-01

    Full Text Available Intestinal pathologies due to ovarian cyst are observed rarely. Although a limited number of cases in neonatal and adolescent periods have been observed, no adult case has been reported in the literature. Two mechanisms are involved in intestinal complications due to ovarian cysts: torsion due to adhesion or compression of giant ovarian mass with a diameter of 9-10 cm. We report here a terminal ileum necrosis case due to compression by an ovarian cyst with 11 × 10 × 7 cm size in an 81-year-old woman.

  6. Ionizing radiation dose due to the use of agricultural fertilizers

    International Nuclear Information System (INIS)

    Umisedo, Nancy Kuniko

    2007-01-01

    Among several agents that exist in the environment which can expose to different risks and effects, there is the ionizing radiation whose knowledge of dose is of importance to the effective control and prevention of possible damages to human beings and to the environment. The transfer of radionuclides from fertilizers to/and soils to the foodstuffs can result as an increment in the internal dose when they are consumed by the human beings. This work evaluates the contribution of fertilizers to the ionizing radiation dose in the environment and in the human being. Samples of fertilizers, soils and vegetables produced in fertilized soils were analysed through gamma spectrometry with the use of a hyper pure germanium detector. Measurements of ambient dose with thermoluminescent dosimeters were also performed. In the fertilized soil samples values of specific activities from 36 to 342 Bq/kg for K-40, from 42 to 142 Bq/kg for U-238 and from 36 to 107 Bq/kg for Th-232 were obtained. In the vegetables the values varied from 21 to 118 Bq/kg for K-40 and for the elements of uranium and thorium series the values were less than 2 Bq/kg. In fertilizers the maximum value of 5800 Bq/kg was obtained for K-40, 430 Bq/kg for U-238 and 230 Bq/kg for Th-232. The average values of soil to plant transfer factor were not significantly different among the types of vegetables. The annual committed effective dose of 0.882 μSv due to the ingestion of K-40 from the analysed vegetables is very small if compared to the reference value of 170 μv given by United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR, 2000). The thermoluminescent dosimetry provided the annual ambient dose equivalent from 1.5 to 1.8 mSv without differences between cultivated and non cultivated fields. Through the results obtained, it was not observed a significant transfer of radionuclides from fertilizers to soils and to foodstuffs in the conditions adopted in this work and consequently there

  7. Hyporheic expansion and contraction due to hydrologic forcing

    Science.gov (United States)

    Lowry, Chris; Malzone, Jonathan; Schmadel, Noah; Ward, Adam

    2017-04-01

    The hyporheic zone is dynamic in both space and time providing a critical zone for stream metabolism and biogeochemical cycling. In considering the extent and volume of the hyporheic zone, geomorphology is considered the primary control in many settings. However, superimposed on top of these geomorphologic features are dynamic hydrologic forcing from the stream, groundwater, and hillslope, which cause the hyporheic zone to expand and contract. In some setting, hydrologic forcing alone can produce the same extent and volume of the hyporheic zones in the absence of any geomorphologic feature. The research presented here explores the temporal role of hydrologic forcing on the expansion and contraction of the hyporheic zone. Using a coupled numerical surface and groundwater model we analyze the transient drivers that control the volume of the hyporheic zone by simulating daily, annual, and storm induced stream and groundwater fluctuations. Results show annual groundwater forcing is the dominant control on the volume of the hyporheic zone but this response can be modified by in phase and out of phase surface water dynamics due to storm events. By removing all geomorphologic features we explore the impact of a suite of in phase and out of phase hydrologic forcing on the magnitude and extent of the hyporheic zones. Results show these hydrologic forcing can produce hyporheic flow path lengths and residence times that span orders of magnitude. The span of path lengths and residence times, simply controlled by the superposition of hydrologic signals, are equivalent to those produced by geomorphic features. These results stress the importance of quantifying dynamic hydrologic forcing from the stream, groundwater, and hillslope in future efforts of upscaling to stream networks.

  8. Brief communication: Loss of life due to Hurricane Harvey

    NARCIS (Netherlands)

    Jonkman, Sebastiaan N.; Godfroij, Maartje; Sebastian, Antonia; Kolen, B.

    2018-01-01

    An analysis was made of the loss of life caused by Hurricane Harvey. Information was collected for 70 fatalities that occurred due to the event and were recovered within the first 2 weeks after landfall. Most fatalities occurred due to drowning (81 %), particularly in and around vehicles. Males

  9. Physical Activity and School Absenteeism Due to Illness in Adolescents

    Science.gov (United States)

    de Groot, Renate; van Dijk, Martin; Savelberg, Hans; van Acker, Frederik; Kirschner, Paul

    2017-01-01

    Background: Knowledge about the beneficial role of physical activity (PA) for health and school performance is growing. Studies investigating the link between PA and school absenteeism due to illness are lacking. Therefore, we investigated associations between habitual PA and school absenteeism due to illness in adolescents and explored whether…

  10. Physical activity and school absenteeism due to illness in adolescents

    NARCIS (Netherlands)

    De Groot, Renate; Van Dijk, Martin; Savelberg, Hans; Van Acker, Frederik; Kirschner, Paul A.

    2017-01-01

    Knowledge about the beneficial role of physical activity (PA) for health and school performance is growing. Studies investigating the link between PA and school absenteeism due to illness are lacking. Therefore we investigated associations between habitual PA and school absenteeism due to illness in

  11. Recurrent bilateral periorbital and circumoral bruising due to vomiting.

    Science.gov (United States)

    Al-Sardar, Hussain; Ai-Sardar, Hussain

    2014-04-02

    Periorbital ecchymosis is due to extravasations of blood into the periorbital skin and the subcutaneous tissues around the eyes. 'raccoon eyes' or 'panda sign' is a distinctive type of periorbital ecchymosis where the bruising is characterised by tarsal sparing. This sparing is due to an anatomical structure called the orbital septum, which limits the spread of the discolouration beyond the tarsal plate. Hence 'raccoon eyes' description should be limited to orbital ecchymosis due to basal skull fractures only. While the bilateral bruising due to direct trauma to the eyes, or non-traumatic medical conditions, can spread beyond the tarsal plate as in our case. The differential diagnosis varies from trivial benign conditions to serious life-threatening illnesses. We describe a case of recurrent bilateral periorbital ecchymosis and facial bruising due to vomiting.

  12. Risk Due to Radiological Terror Attacks With Natural Radionuclides

    Science.gov (United States)

    Friedrich, Steinhäusler; Stan, Rydell; Lyudmila, Zaitseva

    2008-08-01

    The naturally occurring radionuclides radium (Ra-226) and polonium (Po-210) have the potential to be used for criminal acts. Analysis of international incident data contained in the Database on Nuclear Smuggling, Theft and Orphan Radiation Sources (CSTO), operated at the University of Salzburg, shows that several acts of murder and terrorism with natural radionuclides have already been carried out in Europe and Russia. Five different modes of attack (T) are possible: (1) Covert irradiation of an individual in order to deliver a high individual dose; (2) Covert irradiation of a group of persons delivering a large collective dose; (3) Contamination of food or drink; (4) Generation of radioactive aerosols or solutions; (5) Combination of Ra-226 with conventional explosives (Dirty Bomb). This paper assesses the risk (R) of such criminal acts in terms of: (a) Probability of terrorist motivation deploying a certain attack mode T; (b) Probability of success by the terrorists for the selected attack mode T; (c) Primary damage consequence (C) to the attacked target (activity, dose); (d) Secondary damage consequence (C') to the attacked target (psychological and socio-economic effects); (e) Probability that the consequences (C, C') cannot be brought under control, resulting in a failure to manage successfully the emergency situation due to logistical and/or technical deficits in implementing adequate countermeasures. Extensive computer modelling is used to determine the potential impact of such a criminal attack on directly affected victims and on the environment.

  13. Risk Due to Radiological Terror Attacks With Natural Radionuclides

    International Nuclear Information System (INIS)

    Friedrich, Steinhaeusler; Lyudmila, Zaitseva; Stan, Rydell

    2008-01-01

    The naturally occurring radionuclides radium (Ra-226) and polonium (Po-210) have the potential to be used for criminal acts. Analysis of international incident data contained in the Database on Nuclear Smuggling, Theft and Orphan Radiation Sources (CSTO), operated at the University of Salzburg, shows that several acts of murder and terrorism with natural radionuclides have already been carried out in Europe and Russia. Five different modes of attack (T) are possible: (1) Covert irradiation of an individual in order to deliver a high individual dose; (2) Covert irradiation of a group of persons delivering a large collective dose; (3) Contamination of food or drink; (4) Generation of radioactive aerosols or solutions; (5) Combination of Ra-226 with conventional explosives (Dirty Bomb).This paper assesses the risk (R) of such criminal acts in terms of: (a) Probability of terrorist motivation deploying a certain attack mode T; (b) Probability of success by the terrorists for the selected attack mode T; (c) Primary damage consequence (C) to the attacked target (activity, dose); (d) Secondary damage consequence (C') to the attacked target (psychological and socio-economic effects); (e) Probability that the consequences (C, C') cannot be brought under control, resulting in a failure to manage successfully the emergency situation due to logistical and/or technical deficits in implementing adequate countermeasures. Extensive computer modelling is used to determine the potential impact of such a criminal attack on directly affected victims and on the environment

  14. Colour of tropical wood and discolouration due to simulated sunlight

    Directory of Open Access Journals (Sweden)

    Jana Baar

    2010-01-01

    Full Text Available This study investigated the wood surface discolouration due to simulated sunlight of three tropical woods native in South America. These woods are commonly used in the Czech Republic. Wood of jatoba (Hymenea courbaril L., massaranduba (Manilkara bidentata A. Chev. and tigerwood (Astronium graveolens Jacq. was exposed to treatment by light of xenon-arc lamp, which simulates outdoor sunlight, for 144 hours. Colour measurements of exposed and non-exposed areas of samples were performed by means of spectrophotometer measuring in CIEL*a*b* colour system. The resulting wood discolouration was evaluated according to value of the overall colour change ∆E*. Changes of particular parameters (L*, a* and b* were also observed during exposure. The wood surface darkened rapidly during the first hours of exposure to simulated sunlight, then samples showed only a slight increase in lightness. After 144 hours of sunlight irradiation the values of chromaticity coordinates were lower compared with the original surface. The initial variations in the lightness of different wood decreased to the minimum after exposure. The most distinctive discolouration of wood was found in the initially brightest wood tigerwood, the darkest massaranduba was affected the least.

  15. Continuing the quest for autoimmunity due to oral metal exposure.

    Science.gov (United States)

    Rachmawati, Dessy; Muris, Joris; Scheper, Rik J; Rustemeyer, Thomas; Kleverlaan, Cornelis J; Feilzer, Albert J; von Blomberg, B Mary E; van Hoogstraten, Ingrid M W

    2015-01-01

    The role of metal exposure in the development of autoimmune disease (AID) is still controversial. Here, we studied the relationship between oral metal exposure, metal allergy and autoimmunity. A mixed population (n = 78) of non-allergic volunteers, metal-allergic patients and patients with oral problems putatively due to metal alloys was evaluated for oral Ni, Pd, Au and Hg exposure and skin hypersensitivity. Clinical autoimmune parameters were based on medical histories; additionally, serum levels of the four most common autoantibodies were measured. Skin hypersensitivity, as seen mainly for Ni and/or Pd, was not positively associated with autoimmune parameters. In contrast, metal hypersensitive individuals showed an extremely low frequency of thyroid autoantibodies (3% vs 20% in non-hypersensitive controls). Next, the relation between metal exposure and autoimmunity was evaluated in individuals >35 years (n = 58), since from that age on metal exposure had plateaued and was not correlated with age. In this subgroup, oral Ni exposure was associated (p oral Pd, Au or Hg contacts were not associated with any of the clinical or serological autoimmune phenomena tested. The results of this study support the view that development of metal contact allergies may prevent autoimmune activation, and, second, that oral exposure to Pd, Au or Hg does not facilitate the development of AID.

  16. Future southcentral US wildfire probability due to climate change

    Science.gov (United States)

    Stambaugh, Michael C.; Guyette, Richard P.; Stroh, Esther D.; Struckhoff, Matthew A.; Whittier, Joanna B.

    2018-01-01

    Globally, changing fire regimes due to climate is one of the greatest threats to ecosystems and society. In this paper, we present projections of future fire probability for the southcentral USA using downscaled climate projections and the Physical Chemistry Fire Frequency Model (PC2FM). Future fire probability is projected to both increase and decrease across the study region of Oklahoma, New Mexico, and Texas. Among all end-of-century projections, change in fire probabilities (CFPs) range from − 51 to + 240%. Greatest absolute increases in fire probability are shown for areas within the range of approximately 75 to 160 cm mean annual precipitation (MAP), regardless of climate model. Although fire is likely to become more frequent across the southcentral USA, spatial patterns may remain similar unless significant increases in precipitation occur, whereby more extensive areas with increased fire probability are predicted. Perhaps one of the most important results is illumination of climate changes where fire probability response (+, −) may deviate (i.e., tipping points). Fire regimes of southcentral US ecosystems occur in a geographic transition zone from reactant- to reaction-limited conditions, potentially making them uniquely responsive to different scenarios of temperature and precipitation changes. Identification and description of these conditions may help anticipate fire regime changes that will affect human health, agriculture, species conservation, and nutrient and water cycling.

  17. Years of potential life lost due to motorcycle accidents

    Directory of Open Access Journals (Sweden)

    Flávia Emília Cavalcante Valença Fernandes

    2017-05-01

    Full Text Available Introduction: Traffic accidents represent a serious public health problem, because they kill approximately 1.24 million persons annually, and leave another 20 to 50 million with non-fatal lesions and traumatisms worldwide. In Brazil, in the year 2011, motorcyclists alone were responsible for one third of these deaths. Therefore, the aim of this study was to estimate the years of potential life lost due to motorcycle accidents, according to sex and age group, and analyze the trend of the indicator for the state of Pernambuco in the period from 2005 to 2014. Methods and Results an ecological study based on data from the System of Information about Mortality was used. The indicator and rate were calculated by using the age limit of 70 years. The linear regression model and Kruskal-Wallis and Mann-Whitney tests were used, at the level of significance of 5% and confidence of 95%. The most affected sex and age-range were men between 20-29 years of age. The rates followed a trend of growth in both sexes, in the young population with the exception of those from 10 to 19 years of age. Conclusions: This context points out the magnitude and precociousness of motorcycle accidents in both sexes and the young population.

  18. Fatal anoxia due to rachacha consumption: Two cases reported.

    Science.gov (United States)

    Monteil-Ganiere, Catherine; Gaulier, Jean-Michel; Chopineaux, Daniel; Barrios, Lucia; Pineau, Alain; Dailly, Éric; Clément, Renaud

    2014-12-01

    Deaths due to ingesting rachacha, which is a homemade paste obtained by decocting poppy heads, are very rare. No fatalities have been recorded in scientific publications. This product is not considered to be very dangerous by its users. We are reporting the first deaths (a 30-year-old man and a 28-year-old woman), after ingesting rachacha balls and alcohol consumption during an evening with a friend. Signs compatible with acute anoxia were observed during autopsy. Toxicological analyses highlighted the presence of morphine and codeine in the blood, urine and bile, with an absence of 6-acetylmorphine. Concomitant consumption of alcohol certainly played a role in the occurrence of death. The black paste found at the scene was identified as rachacha. The mean of consumption (orally) was confirmed by the presence of morphine and codeine in the gastric contents of both victims. The analysis of hair samples was performed to reveal the substance consumption history. Therefore, a possibility of contamination by sweat and/or putrefactive liquids in the post-mortem period must be considered for the interpretation of the results. These two cases show that taking rachacha can be dangerous, especially when combined with the consumption of substances which could potentiate respiratory depression induced by morphine. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Occupational allergy due to seafood delivery: Case report

    Directory of Open Access Journals (Sweden)

    Trautmann Axel

    2008-05-01

    Full Text Available Abstract Background Sensitization to fish or crustaceans requires intensive skin contact and/or airway exposition and therefore especially workers in the seafood processing industry may develop an occupational seafood allergy. However, even in jobs with limited direct exposure, individuals with atopic disposition not using appropriate skin protection are at risk for developing occupational seafood allergy which requires termination of employment. Case presentation Due to increasing workload and pressure of time a truck driver in charge of seafood deliveries for 10 years neglected preventive measures such as wearing protective cloths and gloves which resulted in increasing direct skin contact to seafood or mucosal contact to splashing storage ice. Despite his sensitization to fish and crustaceans he tried to remain in his job but with ongoing incidental allergen exposure his symptoms progressed from initial contact urticaria to generalized urticaria, anaphylaxis and finally occupational asthma. Conclusion Faulty knowledge and increased work load may impede time-consuming usage of preventive measures for occupational health and safety. In predisposed atopic individuals even minor allergen exposure during seafood distribution may lead to occupational seafood allergy. With ongoing allergen exposure progression to potentially life-threatening allergy symptoms may occur.

  20. Bending and Deformation of Sandwich Panels Due to Localized Pressure

    Directory of Open Access Journals (Sweden)

    Bambang K. Hadi

    2005-05-01

    Full Text Available Bending and deformation of sandwich panels due to localized pressure were analyzed using both Rayleigh-Ritz and finite element methods. The faces were made of laminated composite plates, while the core was a honeycomb material. Carbon fiber and glass fiber reinforced plastics were used for composite plate faces. In the case of Rayleigh-Ritz method, first the total energy of the system was calculated and then taking the variations of the total energy, the sandwich panel deflections could be computed. The deflections were assumed by means of Fourier series. A finite element code NASTRAN was exploited extensively in the finite element method. 3-dimensional 8-node brick elements were used to model sandwich panels, for both the faces sheets and the core. The results were then compared to each other and in general they are in good agreements. Dimple phenomena were found in these cases. It shows that localized pressure on sandwich structures will produce dimple on the pressurize region with little effects on the rest of the structures.

  1. Clostridium Difficile Infection Due to Pneumonia Treatment: Mortality Risk Models.

    Science.gov (United States)

    Chmielewska, M; Zycinska, K; Lenartowicz, B; Hadzik-Błaszczyk, M; Cieplak, M; Kur, Z; Wardyn, K A

    2017-01-01

    One of the most common gastrointestinal infection after the antibiotic treatment of community or nosocomial pneumonia is caused by the anaerobic spore Clostridium difficile (C. difficile). The aim of this study was to retrospectively assess mortality due to C. difficile infection (CDI) in patients treated for pneumonia. We identified 94 cases of post-pneumonia CDI out of the 217 patients with CDI. The mortality issue was addressed by creating a mortality risk models using logistic regression and multivariate fractional polynomial analysis. The patients' demographics, clinical features, and laboratory results were taken into consideration. To estimate the influence of the preceding respiratory infection, a pneumonia severity scale was included in the analysis. The analysis showed two statistically significant and clinically relevant mortality models. The model with the highest prognostic strength entailed age, leukocyte count, serum creatinine and urea concentration, hematocrit, coexisting neoplasia or chronic obstructive pulmonary disease. In conclusion, we report on two prognostic models, based on clinically relevant factors, which can be of help in predicting mortality risk in C. difficile infection, secondary to the antibiotic treatment of pneumonia. These models could be useful in preventive tailoring of individual therapy.

  2. Radiation dose distributions due to sudden ejection of cobalt device

    International Nuclear Information System (INIS)

    Abdelhady, Amr

    2016-01-01

    The evaluation of the radiation dose during accident in a nuclear reactor is of great concern from the viewpoint of safety. One of important accident must be analyzed and may be occurred in open pool type reactor is the rejection of cobalt device. The study is evaluating the dose rate levels resulting from upset withdrawal of co device especially the radiation dose received by the operator in the control room. Study of indirect radiation exposure to the environment due to skyshine effect is also taken into consideration in order to evaluate the radiation dose levels around the reactor during the ejection trip. Microshield, SHLDUTIL, and MCSky codes were used in this study to calculate the radiation dose profiles during cobalt device ejection trip inside and outside the reactor building. - Highlights: • This study aims to calculate the dose rate profiles after cobalt device ejection from open-pool-type reactor core. • MicroShield code was used to evaluate the dose rates inside the reactor control room. • McSKY code was used to evaluate the dose rates outside the reactor building. • The calculated dose rates for workers are higher than the permissible limits after 18 s from device ejection.

  3. Hypothermia due to Antipsychotic Medication: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Cherryl Zonnenberg

    2017-09-01

    Full Text Available BackgroundHypothermia is a rare, but potentially fatal adverse effect of antipsychotic drug (APD use. Although the opposite condition, hyperthermia, has been researched extensively in the context of the malignant antipsychotic syndrome, little is known about hypothermia due to APDs.ObjectiveThis study aimed to review the literature on hypothermia in the context of APD use, and formulate implications for research and clinical care.MethodsA systematic search was made in PubMed and Ovid Medline.ResultsThe literature search yielded 433 articles, including 57 original case descriptions of hypothermia developed during APD use with non-toxic plasma levels. All cases together indicate that the risk of developing hypothermia is highest during the 7 days following initiation, or increase in dosage, of APDs, especially in the presence of additional predisposing factors, such as advanced age, exposure to cold, adjuvant use of benzodiazepines, and (subclinical hypothyroidism. In addition, data derived from drug-monitoring agencies suggest that the prevalence of APD-related hypothermia is at least 10 times higher than suggested by the literature.ConclusionWe conclude that health-care professionals need to monitor the body temperature of patients starting with (an increased dose of APDs for a duration of 7–10 days to prevent hypothermia, especially in the presence of multiple risk factors. Moreover, systematic studies are needed to establish the actual prevalence of APD-related hypothermia as well as the relative risk for individual APDs.

  4. sICAM-1 in meningoencephalitis due to Angiostrongylus cantonensis

    Directory of Open Access Journals (Sweden)

    Dorta-Contreras Alberto Juan

    2006-01-01

    Full Text Available INTRODUCTION: Angiostrongylus cantonensis meningoencephalitis is an emergent disease in the Americas. METHOD: Twelve children suffering from eosinophilic meningoencephalitis due to this parasite aged between 6-10 years were studied. Cerebrospinal fluid (CSF and serum samples were taken simultaneously in the first diagnostic puncture at admission. RESULTS: All cases showed typical findings on the routine CSF and serum analysis: increased CSF total protein, increased Q (CSF/serum albumin accompanied by eosinophilia in CSF. No intrathecal synthesis of immunoglobulins was found. Mean serum and CSF sICAM-1 values were 337.4 and 3.97 ng/mL. Qalbumin and QsICAM-1 mean values were 4.1 and 6.2 respectively. In 50% of the patients an increased brain-derived fraction of sICAM-1 was found. CONCLUSION: It may be suggested that a dynamic of the sICAM-1 brain derived fraction is perhaps associated to the immune response in the evolution of the disease.sICAM-1 may be an agent in negative feedback for eosinophils passage through the blood-CSF barrier into the inflammatory brain response.

  5. Cushing's syndrome due to interaction between inhaled corticosteroids and itraconazole.

    Science.gov (United States)

    Bolland, Mark J; Bagg, Warwick; Thomas, Mark G; Lucas, Jennifer A; Ticehurst, Rob; Black, Peter N

    2004-01-01

    To report a case of an interaction between inhaled corticosteroids and itraconazole causing iatrogenic Cushing's syndrome and provide a review of the relevant literature. A 70-year-old white woman on long-term treatment with high-dose inhaled corticosteroids for asthma was diagnosed as having Scedosporium apiospermum infection of the skin and subcutaneous tissues. As a result, she was treated with itraconazole for 2 months. She subsequently developed Cushing's syndrome due to a probable cytochrome P450-mediated interaction between itraconazole and budesonide. She also had secondary adrenal insufficiency requiring prolonged treatment with replacement hydrocortisone. Budesonide is a potent glucocorticoid that is metabolized in the liver by the CYP3A4 isoenzyme to inactive metabolites. Itraconazole is a potent cytochrome P450 inhibitor. It can inhibit the metabolism of oral or inhaled corticosteroids, producing cortisol excess leading to Cushing's syndrome and adrenal insufficiency. An assessment of causality indicated a possible adverse interaction between itraconazole and budesonide. The combination of itraconazole and inhaled corticosteroids is increasingly being used to treat conditions such as allergic bronchopulmonary aspergillosis. Clinicians need to be aware of the potential for an interaction between such a combination.

  6. Occupational irritant contact dermatitis due to petroleum naphtha

    Directory of Open Access Journals (Sweden)

    Aslı Aytekin

    2014-12-01

    Full Text Available Irritant contact dermatitis (ICD is responsible for the vast majority of occupational contact dermatitis and usually seen in professional groups working with wet hand. However, today, with the increasing business lines, employees are exposed to a variety of irritants. Occupational exposure to many chemicals and toxic irritants affect not only the skin, but also the other systems. Therefore, this situation resulting with loss of work and changes in business may become a public health problem. The diagnosis of occupational contact dermatitis should not be limited only with tests for allergens, detailed history of exposure to workplace substances and careful examination of product safety forms are necessary. In addition, by establishing close relationship between occupational physicians and employers, preventive measures should be taken before similar diseases occur in other workers in the same work place. In order to highlight this issue, a 32-year-old male patient working in an invitation card fabric is presented in this case report. Irritant contact dermatitis secondary to “petroleum naphta” was present in the patient’s arms. Another important feature of this case, as far as we know, this is the first case of irritant contact dermatitis due to naphtha in the literature.

  7. Iron Loading and Overloading due to Ineffective Erythropoiesis

    Directory of Open Access Journals (Sweden)

    Toshihiko Tanno

    2010-01-01

    Full Text Available Erythropoiesis describes the hematopoietic process of cell proliferation and differentiation that results in the production of mature circulating erythrocytes. Adult humans produce 200 billion erythrocytes daily, and approximately 1 billion iron molecules are incorporated into the hemoglobin contained within each erythrocyte. Thus, iron usage for the hemoglobin production is a primary regulator of plasma iron supply and demand. In many anemias, additional sources of iron from diet and tissue stores are needed to meet the erythroid demand. Among a subset of anemias that arise from ineffective erythropoiesis, iron absorption and accumulation in the tissues increases to levels that are in excess of erythropoiesis demand even in the absence of transfusion. The mechanisms responsible for iron overloading due to ineffective erythropoiesis are not fully understood. Based upon data that is currently available, it is proposed in this review that loading and overloading of iron can be regulated by distinct or combined mechanisms associated with erythropoiesis. The concept of erythroid regulation of iron is broadened to include both physiological and pathological hepcidin suppression in cases of ineffective erythropoiesis.

  8. Vocal cord paralysis due to extralaryngeal causes : evaluation with CT

    International Nuclear Information System (INIS)

    Lee, Jong Hwa; Mo, Jong Hyun; Moon, Sung Hee; Na, Dong Gyu; Byun, Hong Sik; Cho, Jae Min; Han, Boo Kyung; Son, Young Ik; Baek, Chung Whan

    1999-01-01

    To evaluate the use of CT in patients with vocal cord paralysis due to extralaryngeal causes, and to use CT for the assessment of extralaryngeal diseases causing vocal cord paralysis. We prospectively studied the results of CT in 41 patients with vocal cord paralysis in whom laryngoscopy revealed no laryngeal cause and physical examination demonstrated no definite extralaryngeal cause. The extralaryngeal cause of vocal cord palsy was determined after comprehensive clinical diagnosis. Enhanced CT scans were acquired from the skull base and continued to the level of the aorticopulmonary window. We used CT to assess the detection rate for extralaryngeal causes and to extimate the extent of extralaryngeal disease and the distribution of lesions. CT revealed that in 20 of 41 patients(49%) the extralarygeal causes of vocal paralysis were as follows : thyroid cancer(n=10), nodal disease(n=6), esophageal cancer(n=2), neurogenic tumor(n=1), aortic aneurysm(n=1). Lesions were located on the left side in 13 patients(65%), and in the tracheoesophageal groove in 15(75%). In patients with vocal cord paralysis in whom no definite lesion is seen on physical examination , CT could be a useful primary imaging method for the assessment of extralaryngeal causes

  9. [Intestinal perforation due to multiple magnet ingestion: a case report].

    Science.gov (United States)

    Cevizci, Mehmet Nuri; Karadağ, Cetin Ali; Demir, Mesut; Dokucu, Ali Ihsan

    2012-03-01

    Multiple magnet ingestion during childhood may result in emergency situations. A single magnet may be discharged with intestinal peristalsis, but multiple magnets may stick together and cause significant intestinal complications. Here we present a case with intestinal perforation due to ingestion of multiple magnets and metal pieces. An eight-year-old girl presented with abdominal pain and vomiting. She had abdominal tenderness and defense on the physical examination. Abdominal X-ray showed air and fluid levels. Metallic images were not considered at first as important in the diagnosis. Abdominal ultrasonography was reported as acute appendicitis. During the abdominal exploration, the appendix was normal, but there were dense adherences around the ileum and cecum. After adhesiolysis, intestinal perforations were seen in the cecum and 15 and 45 cm proximal to the cecum. Magnet and metal pieces were present in the perforated segments. Wedge resection and primary repair was performed. There were no postoperative complications, and she was discharged on the postoperative fifth day. Pediatric surgeons should be aware of the complications of multiple magnet ingestion. If the patient has a history of multiple magnet ingestion, follow-up with daily abdominal X-rays should be done, and in cases where magnets seem to cluster together or if acute abdominal signs develop, surgical exploration should be considered.

  10. Occupational doses due to photoneutrons in medical linear accelerators rooms

    International Nuclear Information System (INIS)

    Soares, Alessandro Facure Neves de Salles

    2006-04-01

    Medical linear accelerators, with maximum photon energies above 10 MeV, are becoming of common use in Brazil. Although desirable in the therapeutic point of view, the increase in photon energies causes the generation of undesired neutrons, which are produced through nuclear reactions between photons and the high Z target nuclei of the materials that constitute the accelerator head. In this work, MCNP simulation was undertaken to examine the neutron equivalent doses around the accelerators head and at the entrance of medical linear accelerators treatment rooms, some of them licensed in Brazil by the National Regulatory Agency (CNEN). The simulated neutron dose equivalents varied between 2 e 26 μ Sv/Gy RX , and the results were compared with calculations performed with the use of some semi-empirical equations found in literature. It was found that the semi-empirical equations underestimate the simulated neutron doses in the majority of the cases, if compared to the simulated values, suggesting that these equations must be revised, due to the increasing number of high energy machines in the country. (author)

  11. Polymicrobial Infection of the Cornea Due to Contact Lens Wear

    Directory of Open Access Journals (Sweden)

    Selçuk Sızmaz

    2016-04-01

    Full Text Available A 38-year-old male presented with pain and redness in his left eye. He had a history of wearing contact lenses. His ophthalmic examination revealed a large corneal ulcer with surrounding infiltrate. Cultures were isolated from the contact lenses, lens solutions, storage cases, and conjunctivae of both eyes and also corneal scrapings of the left eye. Fortified vancomycin and amikacin drops were started hourly. Culture results of conjunctivae of each eye and left cornea were positive for Pseudomonas aeruginosa; cultures from the contact lenses, lens solution and storage case of both eyes revealed Pseudomonas aeruginosa and Alcaligenes xylosoxidans. Polymerase chain reaction of the corneal scraping was positive for Acanthameoba. The topical antibiotics were changed with ones that both bacteria were sensitive to and anti-amoebic therapy was added. The patient had two recurrences following initial presentation despite intensive therapy. Keratitis occurred due to multiple pathogens; the relapsing course despite adequate therapy is potentially associated with this polymicrobial etiology.

  12. Environmental risks due to radionuclide releases Environmental Risks Due To Radionuclide Releases From The Oil And Gas Industry

    International Nuclear Information System (INIS)

    Steinhausler, F.

    2005-01-01

    Full text : Exploration and transport in the oil- and gas industry result in the release of elevated levels of natural radioactivity into the environment. This has the following impact: Due to the large volumes of water needed during the extraction of gas and oil the resulting waste water can contain increased concentration of natural radionuclides, such as radium (Ra 226) and its decay products; At the oil/water interface waste water and sludge precipitate and form scalings, containing elevated levels of radium (Ra 226); At oil- and gas extraction sites tanks and equipment can be coated with long-lived radon (Rn 222) decay products; Along oil- and gas pipelines (e.g., at compressor stations) radon (Rn 222) decay products can be deposited internally on metal surfaces, such as valves. Typical U 238-series concentration values in production water range from 8 to 42 kBq/ m3, respectively in scale from 1 to 1 000 kBq/kg. In addition, oil- and gas extraction results in significant releases of natural radionuclides to the atmosphere (Rn 222) and to the water (Th 228, Ra 226, Rn 222, Pb 210, Po 210); for example, about 0.15 GBq/a of Rn 222 are released to the atmosphere per 106 m3 of oil extracted. The disposal of large amounts of contaminated wastes (scales, sludges) represents an environmental problem for the scrap metal industry (recycling of steel pipes containing scales) and the housing industry (use of sludge for landfill below a residential area). Using data from the oil- and gas industry in Latin America, Europe and the Asia-Pacific region, the various exposure pathways are reviewed. Furthermore, the current efforts in defining a suitable regulatory framework are discussed

  13. Papulosquamous Drug Eruption and Nail Disorder Due to Use Entecavir

    Directory of Open Access Journals (Sweden)

    Pınar Özuğuz

    2013-12-01

    Full Text Available Introduction: Papulosquamous drug eruptions are a group of skin lesions, triggered by various drugs. Hepatitis B is an important health problem all over the world as well as in our country. Entecavir is a nucleoside analogue used in the treatment of chronic hepatitis B. Case: A 56-year-old female patient using entecavir for chronic hepatitis B for four years admitted to our outpatient clinics with dystrophic changes on the finger nails and toe nails, and scaling erythematous lesions of fingers and toes for one year. She had no drug history other than entecavir. Laboratory examination revealed: HbsAg: positive, HBeAg: negative, anti-HBe: positive, HBV DNA: negative, total anti-HDV: negative, and alanine aminotransferase: 32 U/L. Biopsies were taken from the patient's finger and toe nails after three negative fungal examination of native smears. Biopsy results were consistent with drug eruptions and according to these results, the lesions were thought to be a side effect of entecavir. Entecavir treatment was terminated and transaminase levels were followed at regular intervals. Mometasone fruat ointment and moisturizer containing urea (2 times a day/seven days were started for the treatment of skin lesions. Two weeks later the lesions were showed improvement and the patient was called to follow up at regular intervals. Conclusion: To our best knowledge there was only one case report in the literature so far, about drug eruptions with entecavir. Here we described the first case who developed papulosquamous skin eruptions and nail disorders due to treatment of entecavir.

  14. Acidification of floodplains due to river level decline during drought.

    Science.gov (United States)

    Mosley, Luke M; Palmer, David; Leyden, Emily; Cook, Freeman; Zammit, Benjamin; Shand, Paul; Baker, Andrew; W Fitzpatrick, Rob

    2014-06-01

    A severe drought from 2007 to 2010 resulted in the lowest river levels (1.75 m decline from average) in over 90 years of records at the end of the Murray-Darling Basin in South Australia. Due to the low river level and inability to apply irrigation, the groundwater depth on the adjacent agricultural flood plain also declined substantially (1-1.5 m) and the alluvial clay subsoils dried and cracked. Sulfidic material (pH>4, predominantly in the form of pyrite, FeS2) in these subsoils oxidised to form sulfuric material (pHdrought, the rapid raising of surface and ground water levels mobilised acidity in acid sulfate soil profiles to the floodplain drainage channels and this was transported back to the river via pumping. The drainage water exhibited low pH (2-5) with high soluble metal (Al, Co, Mn, Fe, Mn, Ni, and Zn) concentrations, in exceedance of guidelines for ecosystem protection. Irrigation increased the short-term transport of acidity, however loads were generally greater in the non-irrigation (winter) season when rainfall is highest (0.0026 tonnes acidity/ha/day) than in the irrigation (spring-summer) season (0.0013 tonnes acidity/ha/day). Measured reductions in groundwater acidity and increases in pH have been observed over time but severe acidification persisted in floodplain sediments and waters for over two years post-drought. Results from 2-dimensional modelling of the river-floodplain hydrological processes were consistent with field measurements during the drying phase and illustrated how the declining river levels led to floodplain acidification. A modelled management scenario demonstrated how river level stabilisation and limited irrigation could have prevented, or greatly lessened the severity of the acidification. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Individual dose due to radioactivity accidental release from fusion reactor

    Energy Technology Data Exchange (ETDEWEB)

    Nie, Baojie [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); University of Science and Technology of China, Hefei, Anhui, 230027 (China); Ni, Muyi, E-mail: muyi.ni@fds.org.cn [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); Wei, Shiping [Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei, Anhui, 230031 (China); University of Science and Technology of China, Hefei, Anhui, 230027 (China)

    2017-04-05

    Highlights: • Conservative early dose of different unit fusion radioactivity release were assessed. • Data of accident level in INES for fusion reactor were proposed. • Method of environmental restoration time after fusion accident was proposed. • The maximum possible accident level for ITER like fusion reactor is 6. • We need 34–52 years to live after the fusion hypothetical accident. - Abstract: As an important index shaping the design of fusion safety system, evaluation of public radiation consequences have risen as a hot topic on the way to develop fusion energy. In this work, the comprehensive public early dose was evaluated due to unit gram tritium (HT/HTO), activated dust, activated corrosion products (ACPs) and activated gases accidental release from ITER like fusion reactor. Meanwhile, considering that we cannot completely eliminate the occurrence likelihood of multi-failure of vacuum vessel and tokamak building, we conservatively evaluated the public radiation consequences and environment restoration after the worst hypothetical accident preliminarily. The comparison results show early dose of different unit radioactivity release under different conditions. After further performing the radiation consequences, we find it possible that the hypothetical accident for ITER like fusion reactor would result in a level 6 accident according to INES, not appear level 7 like Chernobyl or Fukushima accidents. And from the point of environment restoration, we need at least 69 years for case 1 (1 kg HTO and 1000 kg dust release) and 34–52 years for case 2 (1 kg HTO and 10kg–100 kg dust release) to wait the contaminated zone drop below the general public safety limit (1mSv per year) before it is suitable for human habitation.

  16. Assessment of leukemia caused deaths due to internal radiation exposure

    International Nuclear Information System (INIS)

    Raicevic, J.J.

    2002-01-01

    A problem of finding the number of cancers, which are developed due to internal exposure to radioactive material, is not a trivial task. This problem is generally rather complex, because in case of protracted exposures, latency period may exceed the time of an individual's natural death, i.e. the age at death due to 'natural causes'. In this paper the model for calculating risk caused by an internal exposure (inhalation or ingestion of radioactive material) is modeled as a continuous irradiation till the end of an individual's life, taking into account natural deaths in the observed population. The basic tool in constructing the model were risk coefficients per unit dose, developed earlier [1]. Since an important role in radiation exposure of the people in South Serbia may play internal exposure to depleted uranium (DU), which was extensively used during the NATO bombing of Yugoslavia, the leukemia was chosen as a stochastic effect which is to be considered. For this purpose, some different (artificial) amounts of DU intake were assumed. In order to present the continuous exposure of the whole population living on the contaminated area, the model separately considers those born after the environmental contamination. Therefore, the overall population is divided into two parts: the one which was alive at the time of the release, (LG-Living Generation), and the second one, born after that (FG- Following Generations). The paper primarily intends to present the model for risk calculation for the LG part of population. However, just for the purpose of demonstration of the overall risk model, the contribution of the FG is added to get an overall risk assessment for the case of leukaemia's deaths. Besides cumulative number of cases, which are usually calculated by other models, this model is able to assess differential values, what means it is able to predict the number of cases within a certain specified age and/or time intervals. According to results obtained by the

  17. Assessment of health risks due to hazardous air pollutant emissions from electric utilities.

    Science.gov (United States)

    French, C; Peters, W; Maxwell, B; Rice, G; Colli, A; Bullock, R; Cole, J; Heath, E; Turner, J; Hetes, B; Brown, D C; Goldin, D; Behling, H; Loomis, D; Nelson, C

    1997-11-01

    Hazardous air pollutant (HAP) emissions from electric utilities were evaluated. Cancer risks, as well as noncancer effects, due to inhalation exposure were assessed for 67 HAPs. Also, cancer risks due to multipathway exposure to radionuclide emissions were assessed. In addition, an assessment of the fate of mercury (Hg) through various environmental media was included. Results suggest arsenic, chromium, and nickel are the HAPs that present the highest cancer risk due to inhalation exposure. For noncancer effects due to inhalation exposure, hydrogen chloride appears to present the greatest potential concern. The risks due to multipathway exposure to radionuclides are estimated to be of similar magnitude to the risks posed by inhalation of arsenic and nickel. Mercury is of potential concern for multipathway exposures because it persists in the environmental and bioaccumulates in the aquatic food web. The study suggests there is a plausible link between Hg emissions from utilities and the Hg found in soil, water, and freshwater fish.

  18. 31 CFR 501.806 - Procedures for unblocking funds believed to have been blocked due to mistaken identity.

    Science.gov (United States)

    2010-07-01

    ... believed to have been blocked due to mistaken identity. 501.806 Section 501.806 Money and Finance: Treasury... funds believed to have been blocked due to mistaken identity. When a transaction results in the blocking... party to the transaction believes the funds have been blocked due to mistaken identity, that party may...

  19. Comparing Papanicolaou test results obtained during pregnancy and post-partum.

    Science.gov (United States)

    Suzuki, Kazuhiro; Furuhashi, Madoka; Kawamura, Takuya; Kubo, Michiko; Osato, Kazuhiro; Yamawaki, Takaharu

    2017-04-01

    Cervical cancer onset initially occurs during youth. Papanicolaou tests performed in early pregnancy can detect cervical cancer; however, Papanicolaou tests during pregnancy have been noted to be inaccurate, reflecting changes associated with pregnancy. Therefore, we assessed the effect of pregnancy on Papanicolaou test results. Of 1351 pregnant women who delivered at Ise Red Cross Hospital between January 2010 and December 2014, 1213 underwent Papanicolaou tests at early pregnancy and post-partum. We compared the Papanicolaou test results. The results of the Papanicolaou test were different in 32 patients. Of the 1191 patients negative for intraepithelial lesions or malignancy in early pregnancy, 16 had other cytological abnormalities post-partum. We performed therapeutic conization post-partum in four patients. The Papanicolaou test results in early pregnancy of the four patients were negative for intraepithelial lesions or malignancy in one patient, atypical squamous cells of undetermined significance in one and high-grade squamous intraepithelial lesion in two. The results of the Papanicolaou test during pregnancy may not be accurate because of the influence of hormones associated with pregnancy. Taking advantage of the one-month post-partum screening visit can lead to early detection and treatment of cervical cancer in young people. © 2017 Japan Society of Obstetrics and Gynecology.

  20. Estimation of economic losses due to Peste de Petits Ruminants in small ruminants in India

    Directory of Open Access Journals (Sweden)

    B. Singh

    2014-04-01

    Full Text Available Aim: To develop a simple mathematical model to assess the losses due to peste des petits ruminants (PPR in small ruminants in India. Materials and Methods: The study was based on cases and deaths in goats and sheep due to PPR from the average combined data on ovine/caprine as published by Government of India for the last 5 years (2008-2012. All possible direct and indirect losses due to the disease, viz. mortality losses, losses due to direct reduction in milk/wool yield, losses due to reproduction failure, body weight losses, treatment costs and opportunity costs, were considered to provide estimate of annual economic losses due to PPR in sheep and goats in India. Based on cases and deaths as reported in sample survey studies, the annual economic loss was also estimated. Results: On the basis of data reported by Government of India, the study has shown average annual economic loss of Rs. 167.83 lacs, of which Rs. 125.67 lacs and Rs. 42.16 lacs respectively are due to the incidence of the disease in goats and sheep. Morbidity losses constituted the greater share of the total loss in both goats and sheep (56.99% and 61.34%, respectively. Among different components of morbidity loss, direct body weight loss was the most significant in both goats and sheep. Based on cases and deaths as reported in sample survey studies, the estimated annual economic loss due to PPR in goats and sheep is Rs. 8895.12 crores, of which Rs. 5477.48 and Rs. 3417.64 crores respectively are due to the disease in goats and sheep. Conclusion: The low economic losses as reported based on Government of India data points towards underreporting of cases and deaths due to the disease. The study thus revealed a significant loss due to PPR in small ruminants on a large scale.

  1. EPIC Results from ALICE

    CERN Document Server

    Harris, John W

    2012-01-01

    An overview is presented of the recent heavy ion results from the ALICE experiment at the Large Hadron Collider. These new results are placed in perspective with those from the Relativistic Heavy Ion Collider experiments.

  2. Deformation due to mechanical and thermal sources in generalised ...

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    dimensional problem of thermoelasticity has been considered to investigate the disturbance due to mechanical (horizontal or verti- cal) and thermal source in a homogeneous, thermally conducting orthorhombic material. Laplace–Fourier ...

  3. Corruption and Public Governance: Implication for Customer Due ...

    African Journals Online (AJOL)

    Prof

    DISCIPLINARY JOURNAL, ... Department of Government and Public Administration. Baze University, Abuja. Nigeria ... prevent dirty funds entering the system is due diligence to find out who their customer is and where his or her funds have come ...

  4. Cutaneous leishmaniasis with lymphadenopathy due to Leishmania donovani

    NARCIS (Netherlands)

    Faber, W. R.; Wonders, J.; Jensema, A. J.; Chocholova, E.; Kager, P. A.

    2009-01-01

    Summary We describe a case of cutaneous leishmaniasis with lymphadenopathy due to Leishmania donovani, which was successfully treated with oral miltefosine. Given the increased prevalence of travelling, patients presenting with lymph-node enlargement should have leishmaniasis included in the

  5. Myoclonus epilepsy and ataxia due to KCNC1 mutation

    DEFF Research Database (Denmark)

    Oliver, Karen L; Franceschetti, Silvana; Milligan, Carol J

    2017-01-01

    OBJECTIVE: To comprehensively describe the new syndrome of myoclonus epilepsy and ataxia due to potassium channel mutation (MEAK), including cellular electrophysiological characterization of observed clinical improvement with fever. METHODS: We analyzed clinical, electroclinical, and neuroimaging...

  6. Esophageal perforation due to blunt chest trauma: Difficult diagnosis because of coexisting severe disturbance of consciousness.

    Science.gov (United States)

    Mezuki, Satomi; Shono, Yuji; Akahoshi, Tomohiko; Hisanaga, Kana; Saeki, Hiroshi; Nakashima, Yuichiro; Momii, Kenta; Maki, Jun; Tokuda, Kentaro; Maehara, Yoshihiko

    2017-11-01

    Esophageal perforation due to blunt trauma is a rare clinical condition, and the diagnosis is often difficult because patients have few specific symptoms. Delayed diagnosis may result in a fatal clinical course due to mediastinitis and subsequent sepsis. In this article, we describe a 26-year-old man with esophageal perforation due to blunt chest trauma resulting from a motor vehicle accident. Because a severe disturbance of consciousness masked the patient's trauma-induced thoracic symptoms, we required 11h to diagnose the esophageal perforation. Therefore, the patient developed septic shock due to mediastinitis. However, his subsequent clinical course was good because of prompt combined therapy involving surgical repair and medical treatment after the diagnosis. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Reduction in thermal conductivity of ceramics due to radiation damage

    International Nuclear Information System (INIS)

    Klemens, P.G.; Hurley, G.F.; Clinard, F.W. Jr.

    1976-01-01

    Ceramics are required for a number of applications in fusion reactors. In several of these applications, the thermal conductivity is an important design parameter as it affects the level of temperature and thermal stress in service. Ceramic insulators are known to suffer substantial reduction in thermal conductivity due to neutron irradiation damage. The present study estimates the reduction in thermal conductivity at high temperature due to radiation induced defects. Point, extended, and extended partly transparent defects are considered

  8. Targeting Epigenetic Mechanisms in Pain due to Trauma and TBI

    Science.gov (United States)

    2017-10-01

    AWARD NUMBER: W81XWH-14-1-0579 TITLE: Targeting Epigenetic Mechanisms in Pain due to Trauma and TBI PRINCIPAL INVESTIGATOR: David J. Clark, MD... Epigenetic Mechanisms in Pain due to Trauma and TBI 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) David J. Clark, MD Email... epigenetic changes occurring in the dorsal horn of the spinal cord after either brain or peripheral trauma may support chronic pain. Our work to-date

  9. Physical activity and school absenteeism due to illness in adolescents

    OpenAIRE

    De Groot, Renate; Van Dijk, Martin; Savelberg, Hans; Van Acker, Frederik; Kirschner, Paul A.

    2017-01-01

    Knowledge about the beneficial role of physical activity (PA) for health and school performance is growing. Studies investigating the link between PA and school absenteeism due to illness are lacking. Therefore we investigated associations between habitual PA and school absenteeism due to illness in adolescents and explored whether mental health and cardiovascular fitness mediated this association. 328 Students in grades 7 and 9 (mean age 13.8 years; 49% boys) were included. PA was measured o...

  10. Chorioamnionitis due to Lactococcus lactis cremoris: A case report

    Directory of Open Access Journals (Sweden)

    F. Azouzi

    2015-07-01

    Full Text Available Lactococcus lactis cremoris is rarely involved in human pathology. A thirty two-year old pregnant woman with premature rupture of membrane history presented with chorioamnionitis due to L. lactis cremoris. She underwent an emergency caesarian section and was treated with antibiotics including the association of amoxicillin and clavulanic acid. She was completely recovered. This is the first case to our knowledge of chorioamnionitis due to this organism. Keywords: Chorioamnionitis, Premature rupture of membranes, Lactococcus lactis cremoris

  11. 8 . TOTAL THRUST ON EARTH-RETAlNING STRUCTURES DUE ...

    African Journals Online (AJOL)

    Terz.aghi and Bowles recommended to double the lateral stress value a xJ for the case of a uniform strip load [I]. Hence: (13). Table 2 list values of the influence factor m3 for various ratiQS of n = x0 / b and m = H /b . C. Total Thrust For Stratified Soils due to Point. Load. Total thrust on earth-retaining structure due to point.

  12. Sensitivity in forward modeled hyperspectral reflectance due to phytoplankton groups

    Science.gov (United States)

    Manzo, Ciro; Bassani, Cristiana; Pinardi, Monica; Giardino, Claudia; Bresciani, Mariano

    2016-04-01

    based on the decomposition of the output reflectance variance in partial variances of the output due to each functional group. This approach considers the sensitivity analysis of the model to each variable on its own and the corresponding interaction with the other variables, allowing identifying the single variability as well as the spectral interaction index. The analysis recognized three spectral ranges with specific level of interactions between the inputs. The first part of the spectrum up to 500 nm had average level of 10% of interaction; the second up to 600nm showed values of 5% with a peak around 580nm; the third showed an increasing interaction level until 15% near 715nm. The results presented in this study provide information relating the sensitivity of hyperspectral water reflectance as observable with band setting of the latest generation space- and air-borne sensors depending on different phytoplankton groups. In particular PRISMA was the best in the spectral sensitivity definition in the first part of the spectrum, while APEX in the second and third domain. The Sentinel 3 showed lower performances although in the third domain it was able to identify some spectral features. Results showed the Chlorophyta had high main effect at 440 nm and 480nm; sensitivity indices of phycoerythrin showed peaks at 550-580nm the range and near 680nm; phycocyanin showed high influence at 620-640nm. The research activity is part of the EU FP7 INFORM (Grant No. 606865, http://www.copernicus-inform.eu/).

  13. Modeling Reservoir Formation Damage due to Water Injection for Oil Recovery

    DEFF Research Database (Denmark)

    Yuan, Hao

    2010-01-01

    The elliptic equation for non-Fickian transport of suspension in porous media is applied to simulate the reservoir formation damage due to water injection for oil recovery. The deposition release (erosion of reservoir formation) and the suspension deposition (pore plugging) are both taken...... into account. 1-D numerical simulations are carried out to reveal the erosion of reservoir formation due to water injection. 2-D numerical simulations are carried out to obtain the suspension and deposition profiles around the injection wells. These preliminary results indicate the non-Fickian behaviors...... of suspended reservoir fines and the corresponding formation damage due to erosion and relocation of reservoir fines....

  14. Endobronchial lesion due to pulmonary Fusobacterium nucleatum infection in a child.

    Science.gov (United States)

    Gedik, Ahmet H; Cakir, Erkan; Soysal, Omer; Umutoğlu, Tarık

    2014-03-01

    Clinically significant infections due to the members of the genus Fusobacterium are rare. The clinical manifestations of pulmonary Fusobacterium nucleatum infections range from simple aspiration pneumonia to severe diseases as necrotizing pneumonia, lung abscess, and empyema. Endobronchial lesions and obstructions are rarely seen in children and are often a misdiagnosed result in delay of definitive treatment. Here, we report a case of endobronchial lesion due to pulmonary F. nucleatum infection in an entirely healthy child before illness. This is the first case reported in the literature of endobronchial lesion due to pulmonary F. nucleatum infection. © 2013 Wiley Periodicals, Inc.

  15. 76 FR 70448 - Publication of Inaccurate or Inactive Ocean Common Carrier Tariffs; Order to Show Cause

    Science.gov (United States)

    2011-11-14

    ... submitting Form FMC-1 via the Commission's Web site. A list of the locations of all carrier and conference tariffs submitted on Form FMC-1 is published on the Commission's Web site. The list is updated in real... Container Line, C.A., Piso 16, Torre El Chorro, 007292 Esquina El Chorro, Caracas, Venezuela VOC Steel...

  16. A Public Relations Nightmare: ACLU Class Action Lawsuit Exposes Inaccurate and Inequitable High School Graduation Rates

    Science.gov (United States)

    Watson, Terri N.; Brown, Kathleen M.

    2010-01-01

    Florida's decision to equate a GED to a high school diploma undermines the attempt of No Child Left Behind to close the achievement gap, while infringing on the public's trust. Public trust fosters a culture of systemic equity and social justice, which are necessary for academic excellence (Byrk & Schneider, 2003). Florida's code of ethics for…

  17. FALSE, INACCURATE AND INCOMPLETE NEWS: CHALLENGES FACING JOURNALISTS INVOLUNTARY RECTIFICATION. THE SPANISH EXPERIENCE

    OpenAIRE

    Ángeles Fernández Barrero; Antonio López Hidalgo

    2013-01-01

    Journalists must verify information provided by their sources. However, factors such as job precariousness, urgency and the credibility they give to mainly institutional sources mean that journalists do not verify information. Most codes of conduct recommend the duty to correct information as soon as an unintentionally committed error is discovered, but journalists dislike recognising their own errors and even more so correcting them publicly. These circumstances affect adversely the quality ...

  18. Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase

    Czech Academy of Sciences Publication Activity Database

    Urban, M.; Joubert, Nicolas; Hocek, Michal; Alexander, R. E.; Kuchta, R. D.

    2009-01-01

    Roč. 48, č. 46 (2009), s. 10866-10881 ISSN 0006-2960 R&D Projects: GA MŠk LC512; GA AV ČR IAA400550902 Grant - others:NIH(US) AI059764 Institutional research plan: CEZ:AV0Z40550506 Keywords : HSV-1 * herpes simplex virus-1 * Pyr * pyrimidine Subject RIV: CC - Organic Chemistry Impact factor: 3.226, year: 2009

  19. How (In)accurate are demand forecasts in public works projects?

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent; Skamris, Mette; Buhl, Søren Ladegaard

    2005-01-01

    that forecasters generally do a poor job of estimating the demand for transportation infrastructure projects. For 9 out of 10 rail projects, passenger forecasts are overestimated; the average overestimation is 106%. For half of all road projects, the difference between actual and forecasted traffic is more than...

  20. Polynomial Collocation for Handling an Inaccurately Known Measurement Configuration in Electrical Impedance Tomography

    DEFF Research Database (Denmark)

    Hyvönen, Niina; Kaarnioja, V.; Mustonen, L.

    2017-01-01

    The objective of electrical impedance tomography is to reconstruct the internal conductivity of a physical body based on measurements of current and potential at a finite number of electrodes attached to its boundary. Although the conductivity is the quantity of main interest in impedance...

  1. Exploring knowledge transfer within manufacturing networks and codified information characteristics: the hidden dangers of inaccurate information

    NARCIS (Netherlands)

    Steenhuis, H.J.; de Bruijn, E.J.

    2004-01-01

    Technology transfer is an important aspect of, and takes frequently place in, international manufacturing networks. A key component of a specific technology is the knowledge and information that accompanies it. This study explores the difficulties with transferring technological knowledge and

  2. Inaccurate or disparate temperature cues? Seasonal acclimation of terrestrial and aquatic locomotor capacity in newts

    Czech Academy of Sciences Publication Activity Database

    Šamajová, Pavlína; Gvoždík, Lumír

    2010-01-01

    Roč. 24, č. 5 (2010), s. 1023-1030 ISSN 0269-8463 R&D Projects: GA ČR GA206/06/0953; GA MŠk LC06073 Institutional research plan: CEZ:AV0Z60930519 Keywords : acclimation * amphibians * environmental predictability * running * swimming * thermal plasticity * thermal sensitivity Subject RIV: EG - Zoology Impact factor: 4.645, year: 2010

  3. Inaccurate rotational component position in image-free navigated unicompartmental knee arthroplasty

    Directory of Open Access Journals (Sweden)

    Akihiko Toda

    2016-01-01

    Conclusion: In both coronal and sagittal alignments, there were a definite proportion of outliers. The ratio of outliers in rotational alignment was especially higher than that in coronal and sagittal alignments. In UKA, the identification of bony landmarks is difficult because of the small operation field. Therefore, careful surface mapping of particular bony landmarks is necessary, and it is not enough to use image-free navigation system in UKA.

  4. Multi-unit shutdown due to boiler feedwater chemical excursion

    International Nuclear Information System (INIS)

    Diebel, M.E.

    1991-01-01

    Ontario Hydro's Bruce Nuclear Generating Station 'B' consists of four 935 W CANDU units located on the east shore of Lake Huron in the province of Ontario, Canada. On July 25 and 26, 1989 three of the four operating units were shutdown due to boiler feedwater chemical excursions initiated by a process upset in the Water Treatment Plant that provides demineralized make-up water to all four units. The chemicals that escaped from an ion exchange vessel during a routine regeneration very quickly spread through the condensate make-up system and into the boiler feedwater systems. This resulted in boiler sulfate levels exceeding shutdown limits. A total of 260 GWH of electrical generation was unexpectedly made unavailable to the grid at a time of peak seasonal demand. This event exposed several unforeseen deficiencies and vulnerabilities in the automatic demineralized water make-up quality protection scheme, system designs, operating procedures and the ability of operating personnel to recognize and appropriately respond to such an event. The combination of these factors contributed towards turning a minor system upset into a major multi-unit shutdown. This paper provides the details of the actual event initiation in the Water Treatment Plant and describes the sequence of events that led to the eventual shutdown of three units and near shutdown of the fourth. The design inadequacies, procedural deficiencies and operating personnel responses and difficulties are described. The process of recovering from this event, the flushing out of system piping, boilers and the feedwater train is covered as well as our experiences with setting up supplemental demineralized water supplies including trucking in water and the use of rental trailer mounted demineralizing systems. System design, procedural and operational changes that have been made and that are still being worked on in response to this event are described. The latest evidence of the effect of this event on boiler tube

  5. On Distance Scale Bias due to Stellar Multiplicity and Associations

    Science.gov (United States)

    Anderson, Richard I.; Riess, Adam

    2018-01-01

    The Cepheid Period-luminosity relation (Leavitt Law) provides the most accurate footing for the cosmic distance scale (CDS). Recently, evidence has been presented that the value of the Hubble constant H0 measured via the cosmic distance scale differs by 3.4σ from the value inferred using Planck data assuming ΛCDM cosmology (Riess et al. 2016). This exciting result may point to missing physics in the cosmological model; however, before such a claim can be made, careful analyses must address possible systematics involved in the calibration of the CDS.A frequently made claim in the literature is that companion stars or cluster membership of Cepheids may bias the calibration of the CDS. To evaluate this claim, we have carried out the first detailed study of the impact of Cepheid multiplicity and cluster membership on the determination of H0. Using deep HST imaging of M31 we directly measured the mean photometric bias due to cluster companions on Cepheid-based distances. Together with the empirical determination of the frequency with which Cepheids appear in clusters we quantify the combined H0 bias from close associations to be approximately 0.3% (0.20 km s-1 Mpc-1) for the passbands commonly used. Thus, we demonstrate that stellar associations cannot explain the aforementioned discrepancy observed in H0 and do not prevent achieving the community goal of measuring H0 with an accuracy of 1%. We emphasize the subtle, but important, difference between systematics relevant for calibrating the Leavitt Law (achieving a better understanding of stellar physics) and for accurately calibrating the CDS (measuring H0).

  6. Surgical Strategies for Spondylodiscitis due to Lumbar Disc Surgery.

    Science.gov (United States)

    Kucuk, Ahmet; Karademir, Mustafa; Tumturk, Abdulfettah; Ulutabanca, Halil; Ercal, Baris Derya; Senol, Serkan; Menku, Ahmet

    2017-01-01

    Despite different surgical treatment protocols at different centers for spondylodiscitis due to lumbar surgery, there is no consensus on its surgical indications. In this study, we aimed to clarify the steps to be followed in the management and treatment of postoperative spondylodiscitis. The data of 20 cases with postoperative spondylodiscitis were evaluated. C-reactive protein (CRP) was used for diagnosis and follow-up. According to culture results of the infected material obtained from the operated cases, appropriate antibiotic treatment was initiated. In non-operated cases, parenteral empirical antibiotic treatment was implemented. Surgical treatment was planned for cases with clinical and radiological instability, abscess on imaging and those who were nonrespondent to empirical antibiotic treatment. For the cases that clinically recovered and had normal CRP levels, oral antibiotic treatment was continued after parenteral antibiotic treatment. Of the cases; 13 were male (65%) and 7 were femals (35%). The mean age was 56.3 years (32-74). The most prevalent complaints in referral were waist and leg pain. Except one, all cases had increased CRP levels. All patients had spondylodiscitis on magnetic resonance imaging. Seven had radiological and clinical instability and 3 had epidural abscess. The most commonly growing microorganism in culture was Staphylococcus aureus. Surgical treatment was applied to seven cases and medical treatment to 13 cases. In cases with waist pain in the postoperative period, the first potential diagnosis to be considered is spondylodiscitis. Surgical treatment should be implemented for cases resistant to empirical antibiotic treatment, with abscess on imaging, or with lumbar instability.

  7. Review of synergisms in materials erosion due to multispecies impact

    International Nuclear Information System (INIS)

    Haasz, A.A.; Auciello, O.; Stangeby, P.C.

    1985-05-01

    Plasma-surface interaction phenomena have become a subject of major interest because of their relevance in two important technological developments of recent decades, viz, microelectronics and thermonuclear fusion. Microelectronic fabrication often involves the use of relatively low-pressure/low-temperature plasma discharges for etching micron-size features in integrated circuits; here erosion is a desired effect. Fusion plasmas, by contrast, cause erosion of the fusion device inner walls, which is generally not desirable. In both cases surfaces are bombarded simultaneously by plasma species which include ions, neutral atoms, electrons and photons, which might lead to enhanced erosion due to synergistic effects. Work performed to date suggests that similar chemistry may be involved in the erosion process associated with some semiconductor and fusion related materials: SiF 4 , SiCl 4 and CH 4 , are, for example, some of the principal species evolving from Si and C surfaces, when exposed to F, Cl and H atoms, respectively, causing the observed erosion. Considerable effort has been expended on studies involving synergistic effects for semiconductor fabrication. Research on synergism related to the erosion of fusion materials (C and carbon compounds) commenced comparatively recently; however, its importance has been increasingly recognized, and evidence of possible synergistic erosion of graphite has recently been obtained in the PLT fusion device. In light of the the interdisciplinary nature of the subject, experimental and theoretical work on synergistic effects in erosion of both semiconductors and fusion materials will be critically reviewed here in an attempt to unify concepts related to results and mechanisms proposed to explain the observed phenomena, and to explore possible new avenues of research. 128 refs

  8. Warning times for species extinctions due to climate change.

    Science.gov (United States)

    Stanton, Jessica C; Shoemaker, Kevin T; Pearson, Richard G; Akçakaya, H Resit

    2015-03-01

    Climate change is likely to become an increasingly major obstacle to slowing the rate of species extinctions. Several new assessment approaches have been proposed for identifying climate-vulnerable species, based on the assumption that established systems such as the IUCN Red List need revising or replacing because they were not developed to explicitly consider climate change. However, no assessment approach has been tested to determine its ability to provide advanced warning time for conservation action for species that might go extinct due to climate change. To test the performance of the Red List system in this capacity, we used linked niche-demographic models with habitat dynamics driven by a 'business-as-usual' climate change scenario. We generated replicate 100-year trajectories for range-restricted reptiles and amphibians endemic to the United States. For each replicate, we categorized the simulated species according to IUCN Red List criteria at annual, 5-year, and 10-year intervals (the latter representing current practice). For replicates that went extinct, we calculated warning time as the number of years the simulated species was continuously listed in a threatened category prior to extinction. To simulate data limitations, we repeated the analysis using a single criterion at a time (disregarding other listing criteria). Results show that when all criteria can be used, the Red List system would provide several decades of warning time (median = 62 years; >20 years for 99% of replicates), but suggest that conservation actions should begin as soon as a species is listed as Vulnerable, because 50% of replicates went extinct within 20 years of becoming uplisted to Critically Endangered. When only one criterion was used, warning times were substantially shorter, but more frequent assessments increased the warning time by about a decade. Overall, we found that the Red List criteria reliably provide a sensitive and precautionary way to assess extinction

  9. Financial compensation due to municipalities that host radioactive waste deposits

    International Nuclear Information System (INIS)

    Silva, Renata A. da; Simoes, Francisco Fernando L.; Martins, Vivian B.

    2013-01-01

    This work aims to perform calculation about the financial compensation due to municipalities where there is viability for construction of radioactive waste deposits from low and medium activity. Were used like base structure de Resolution No. 96 of August, 10, 2010, entitled 'Model of Calculation For Financial Compensation to Municipalities' where are determinate those principal characteristics by the waste and deposits, such as the half-life, activity level, type of deposits (initial, intermediate or final), costs for construction and maintenance of deposits, demography, between others. The calculation was made according to the temporally or definitive storage for solids waste like personal protection equipment (gloves, shoes, masks, etc) resins and filters used in wastewater treatment, between others, from of nuclear and radioactivity facilities. There are presented some countries that do the compensation, financial or not, for some municipalities for the construction of waste deposits and in some cases, the way that occurred the negotiation between the stake holders, in other words, the local population and the companies. Also are presented others forms of financial compensation in Brazil in consequence of activities in large scale which result in potential risk for the surrounding population and for the environment, like compensation for oil and natural gas, hydropower plants and mining. Were used on methodology the inventory of waste presented on RMBN project (Repository of Waste of Low and Medium Activity) developed by the CDTN which present the implementation of a repository for final storage to radioactive waste. With this was possible to develop a case study with the creation of four scenarios. Values were found which initially range from R$2,6 thousand to R$79,8 thousand for month. Finally are analyzed the possible influences which that values may have on the municipality budget revenue and some divergent points about the resolution. (author)

  10. Interventions aiming to reduce early retirement due to rheumatic diseases

    Directory of Open Access Journals (Sweden)

    Pedro Almeida Laires

    2017-07-01

    Full Text Available Introduction: Aging of the population and early retirement translates into productivity losses to society. Persistence of working life is crucial to counteract this sustainability issue faced by western countries. Musculoskeletal and rheumatic diseases (RD may cause work disability and early exit from work, including early retirement. The objective of this article is to review the current knowledge about interventions aiming to reduce early retirement due to RD. Methods: We searched PubMed and The Cochrane Library for studies either in English or Portuguese between January 2000 and June 2016 that evaluated the impact of interventions targeting early retirement in RD patients still at work. We also searched for grey literature from Portuguese institutional repositories. Results: We identified several published studies testing pharmacologic and non-pharmacologic vocational rehabilitation interventions. None was specifically identified for Portugal. The general low quality of the literature and its inconsistency makes it unfeasible to draw definitive conclusions. However, some broad recommendations might be outlined. An effective intervention must: 1 act upon different levels (e.g. RD patient, workplace, involving several stakeholders (e.g. rheumatologists, occupational physicians, employers; 2 prioritize the right patients (e.g. more disabling RD; and 3 consider the patients’ role, for instance by including an element of patient education and support. Despite the lack of good quality evidence on this field, there seems to be a growing interest in the international scientific community with several ongoing studies promoting such interventions. This promising data will be very useful to set up effective policies. Conclusions: This article summarizes the current knowledge about the impact of interventions to avoid or mitigate early retirement in RD patients. It highlights the demand for further research and it also contributes to aware decision

  11. Seasonal climate change patterns due to cumulative CO2 emissions

    Science.gov (United States)

    Partanen, Antti-Ilari; Leduc, Martin; Damon Matthews, H.

    2017-07-01

    Cumulative CO2 emissions are near linearly related to both global and regional changes in annual-mean surface temperature. These relationships are known as the transient climate response to cumulative CO2 emissions (TCRE) and the regional TCRE (RTCRE), and have been shown to remain approximately constant over a wide range of cumulative emissions. Here, we assessed how well this relationship holds for seasonal patterns of temperature change, as well as for annual-mean and seasonal precipitation patterns. We analyzed an idealized scenario with CO2 concentration growing at an annual rate of 1% using data from 12 Earth system models from the Coupled Model Intercomparison Project Phase 5 (CMIP5). Seasonal RTCRE values for temperature varied considerably, with the highest seasonal variation evident in the Arctic, where RTCRE was about 5.5 °C per Tt C for boreal winter and about 2.0 °C per Tt C for boreal summer. Also the precipitation response in the Arctic during boreal winter was stronger than during other seasons. We found that emission-normalized seasonal patterns of temperature change were relatively robust with respect to time, though they were sub-linear with respect to emissions particularly near the Arctic. Moreover, RTCRE patterns for precipitation could not be quantified robustly due to the large internal variability of precipitation. Our results suggest that cumulative CO2 emissions are a useful metric to predict regional and seasonal changes in precipitation and temperature. This extension of the TCRE framework to seasonal and regional climate change is helpful for communicating the link between emissions and climate change to policy-makers and the general public, and is well-suited for impact studies that could make use of estimated regional-scale climate changes that are consistent with the carbon budgets associated with global temperature targets.

  12. Bacterial Autoimmunity Due to a Restriction-Modification System.

    Science.gov (United States)

    Pleška, Maroš; Qian, Long; Okura, Reiko; Bergmiller, Tobias; Wakamoto, Yuichi; Kussell, Edo; Guet, Călin C

    2016-02-08

    Restriction-modification (RM) systems represent a minimal and ubiquitous biological system of self/non-self discrimination in prokaryotes [1], which protects hosts from exogenous DNA [2]. The mechanism is based on the balance between methyltransferase (M) and cognate restriction endonuclease (R). M tags endogenous DNA as self by methylating short specific DNA sequences called restriction sites, whereas R recognizes unmethylated restriction sites as non-self and introduces a double-stranded DNA break [3]. Restriction sites are significantly underrepresented in prokaryotic genomes [4-7], suggesting that the discrimination mechanism is imperfect and occasionally leads to autoimmunity due to self-DNA cleavage (self-restriction) [8]. Furthermore, RM systems can promote DNA recombination [9] and contribute to genetic variation in microbial populations, thus facilitating adaptive evolution [10]. However, cleavage of self-DNA by RM systems as elements shaping prokaryotic genomes has not been directly detected, and its cause, frequency, and outcome are unknown. We quantify self-restriction caused by two RM systems of Escherichia coli and find that, in agreement with levels of restriction site avoidance, EcoRI, but not EcoRV, cleaves self-DNA at a measurable rate. Self-restriction is a stochastic process, which temporarily induces the SOS response, and is followed by DNA repair, maintaining cell viability. We find that RM systems with higher restriction efficiency against bacteriophage infections exhibit a higher rate of self-restriction, and that this rate can be further increased by stochastic imbalance between R and M. Our results identify molecular noise in RM systems as a factor shaping prokaryotic genomes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Financial compensation due to municipalities that host radioactive waste deposits

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Renata A. da; Simoes, Francisco Fernando L.; Martins, Vivian B., E-mail: renata.amaral@ufrj.br, E-mail: flamego@ien.gov.br, E-mail: vbmartins@gmail.com [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    This work aims to perform calculation about the financial compensation due to municipalities where there is viability for construction of radioactive waste deposits from low and medium activity. Were used like base structure de Resolution No. 96 of August, 10, 2010, entitled 'Model of Calculation For Financial Compensation to Municipalities' where are determinate those principal characteristics by the waste and deposits, such as the half-life, activity level, type of deposits (initial, intermediate or final), costs for construction and maintenance of deposits, demography, between others. The calculation was made according to the temporally or definitive storage for solids waste like personal protection equipment (gloves, shoes, masks, etc) resins and filters used in wastewater treatment, between others, from of nuclear and radioactivity facilities. There are presented some countries that do the compensation, financial or not, for some municipalities for the construction of waste deposits and in some cases, the way that occurred the negotiation between the stake holders, in other words, the local population and the companies. Also are presented others forms of financial compensation in Brazil in consequence of activities in large scale which result in potential risk for the surrounding population and for the environment, like compensation for oil and natural gas, hydropower plants and mining. Were used on methodology the inventory of waste presented on RMBN project (Repository of Waste of Low and Medium Activity) developed by the CDTN which present the implementation of a repository for final storage to radioactive waste. With this was possible to develop a case study with the creation of four scenarios. Values were found which initially range from R$2,6 thousand to R$79,8 thousand for month. Finally are analyzed the possible influences which that values may have on the municipality budget revenue and some divergent points about the resolution. (author)

  14. Limitations due to strong head-on beam-beam interactions (MD 1434)

    CERN Document Server

    Buffat, Xavier; Iadarola, Giovanni; Papadopoulou, Parthena Stefania; Papaphilippou, Yannis; Pellegrini, Dario; Pojer, Mirko; Crockford, Guy; Salvachua Ferrando, Belen Maria; Trad, Georges; Barranco Garcia, Javier; Pieloni, Tatiana; Tambasco, Claudia; CERN. Geneva. ATS Department

    2017-01-01

    The results of an experiment aiming at probing the limitations due to strong head on beam-beam interactions are reported. It is shown that the loss rates significantly increase when moving the working point up and down the diagonal, possibly due to effects of the 10th and/or 14th order resonances. Those limitations are tighter for bunches with larger beam-beam parameters, a maximum total beam-beam tune shift just below 0.02 could be reached.

  15. Energy loss mechanism for suspended micro- and nanoresonators due to the Casimir force

    OpenAIRE

    Gusso, André

    2011-01-01

    A so far not considered energy loss mechanism in suspended micro- and nanoresonators due to noncontact acoustical energy loss is investigated theoretically. The mechanism consists on the conversion of the mechanical energy from the vibratory motion of the resonator into acoustic waves on large nearby structures, such as the substrate, due to the coupling between the resonator and those structures resulting from the Casimir force acting over the separation gaps. Analytical expressions for the ...

  16. Guillain-Barré Syndrome due to CMV Reactivation after Cardiac Transplantation

    Science.gov (United States)

    Steger, Christina Maria; Antretter, Herwig; Höfer, Daniel

    2012-01-01

    A 40-year-old male patient suffered from end-stage heart failure due to ischemic cardiomyopathy and received orthotopic cardiac transplantation in June 2005. The instantaneous postoperative course was uneventful, but, seven months later, he suffered from paralysis in the lower extremities finally resulting in quadriplegia and was admitted to hospital. After laboratory testings the diagnosis of a Guillain-Barré syndrome due to cytomegalovirus reactivation was confirmed. PMID:24860678

  17. Guillain-Barré Syndrome due to CMV Reactivation after Cardiac Transplantation

    Directory of Open Access Journals (Sweden)

    Christina Maria Steger

    2012-01-01

    Full Text Available A 40-year-old male patient suffered from end-stage heart failure due to ischemic cardiomyopathy and received orthotopiccardiac transplantation in June 2005. The instantaneous postoperative course was uneventful, but, seven months later, he suffered from paralysis in the lower extremities finally resulting in quadriplegia and was admitted to hospital. After laboratory testings the diagnosis of a Guillain-Barré syndrome due to cytomegalovirus reactivation was confirmed.

  18. An analysis of the process and results of manual geocode correction

    Directory of Open Access Journals (Sweden)

    Yolanda J. McDonald

    2017-05-01

    Full Text Available Geocoding is the science and process of assigning geographical coordinates (i.e. latitude, longitude to a postal address. The quality of the geocode can vary dramatically depending on several variables, including incorrect input address data, missing address components, and spelling mistakes. A dataset with a considerable number of geocoding inaccuracies can potentially result in an imprecise analysis and invalid conclusions. There has been little quantitative analysis of the amount of effort (i.e. time to perform geocoding correction, and how such correction could improve geocode quality type. This study used a low-cost and easy to implement method to improve geocode quality type of an input database (i.e. addresses to be matched through the processes of manual geocode intervention, and it assessed the amount of effort to manually correct inaccurate geocodes, reported the resulting match rate improvement between the original and the corrected geocodes, and documented the corresponding spatial shift by geocode quality type resulting from the corrections. Findings demonstrated that manual intervention of geocoding resulted in a 90% improvement of geocode quality type, took 42 hours to process, and the spatial shift ranged from 0.02 to 151,368 m. This study provides evidence to inform research teams considering the application of manual geocoding intervention that it is a low-cost and relatively easy process to execute.

  19. Spurious platelet count due to cryoglobulins in a patient with smoldering myeloma

    Directory of Open Access Journals (Sweden)

    Naveen Kakkar

    2014-01-01

    Full Text Available Use of automated hematology analyzers for routine blood count reporting has increased the reproducibility and accuracy of test results. However, at times, these instruments may generate spurious test results. Such results can result in inappropriate investigations or treatment decisions in patients. Spuriously normal or high platelet counts carry the risk of under diagnosis of the true thrombocytopenia with adverse clinical implications. We present a patient with smoldering myeloma with spurious platelet count due to cryoglobulins.

  20. Air pollution effects due to deregulation of the electric industry

    Science.gov (United States)

    Davoodi, Khojasteh Riaz

    ) nuclear sources until the year 2005. Each module was analyzed separately and the result from each module was transferred into the Air Quality Impact model. The model assesses the changes in electricity generation within each module due to deregulation and these changes can then be correlated to the emission of air pollutants in the United States.