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Sample records for in24 sn8 o48

  1. Observation of giant exchange bias in bulk Mn50Ni42Sn8 Heusler alloy

    Science.gov (United States)

    Sharma, Jyoti; Suresh, K. G.

    2015-02-01

    We report a giant exchange bias (EB) field of 3520 Oe in bulk Mn50Ni42Sn8 Heusler alloy. The low temperature magnetic state of the martensite phase has been studied by DC magnetization and AC susceptibility measurements. Frequency dependence of spin freezing temperature (Tf) on critical slowing down relation and observation of memory effect in zero field cooling mode confirms the super spin glass (SSG) phase at low temperatures. Large EB is attributed to the strong exchange coupling between the SSG clusters formed by small regions of ferromagnetic order embedded in an antiferromagnetic (AFM) matrix. The temperature and cooling field dependence of EB have been studied and related to the change in unidirectional anisotropy at SSG/AFM interface. The training effect also corroborates with the presence of frozen (SSG) moments at the interface and their role in EB.

  2. Photoreduction of Carbon Dioxide to Methane Over Sb1.5Sn8.5-x Ti x O19.0 with High Conductivity.

    Science.gov (United States)

    Do, Jeong Yeon; Kwak, Byeong Sub; Kang, Misook

    2018-09-01

    In order to enhance the photoreduction of CO2 to CH4, a new type of photocatalyst, Sb1.5Sn8.5-xTixO19.0, with high conductivity and low bandgap was developed by partially incorporating Ti into the framework of Sb1.5Sn8.5O19.0 (antimony-doped tin oxide, ATO) using a controlled hydrothermal method. XRD and TEM analyses indicated that the Sb1.5Sn8.5-xTixO19.0 particles exhibited a tetragonal crystal structure and were approximately 20 nm in size. Furthermore, the bandgap and conductivity of these materials increased with increasing Ti content. A study of the photoreduction of CO2 with H2O revealed a remarkable increase in the generation of CH4 over the Sb1.5Sn8.5-xTixO19.0 catalysts. In particular, CH4 generation was the highest when Sb1.5Sn8.5Ti1.0O19.0 was used as the photocatalyst, and was three-fold higher than that achieved by using anatase TiO2. Photoluminescence studies showed that the enhanced photocatalytic activity of the Sb1.5Sn8.5-xTixO19.0 materials could be attributed to the interfacial transfer of photogenerated charges, which led to an effective charge separation and inhibition of the recombination of photogenerated electron-hole (e-/h+) pairs.

  3. Interfacial microstructures and solder joint strengths of the Sn-8Zn-3Bi and Sn-9Zn-lAl Pb-free solder pastes on OSP finished printed circuit boards

    Energy Technology Data Exchange (ETDEWEB)

    Lin, C.-T. [Department of Materials Science and Engineering, National United University, 1 Lein-Da, Kung-Ching Li, Miaoli 36003, Taiwan (China); Electronics and Optoelectronics Research Laboratories, Industrial Technology Research Institute, 195 Section 4, Chung-Hsing Road, Chutung, Hsinchu 31040, Taiwan (China); Hsi, C.-S. [Department of Materials Science and Engineering, National United University, 1 Lein-Da, Kung-Ching Li, Miaoli 36003, Taiwan (China); Wang, M.-C. [Faculty of Fragrance and Cosmetics, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 807, Taiwan (China)], E-mail: mcwang@kmu.edu.tw; Chang, T.-C.; Liang, M.-K. [Electronics and Optoelectronics Research Laboratories, Industrial Technology Research Institute, 195 Section 4, Chung-Hsing Road, Chutung, Hsinchu 31040, Taiwan (China)

    2008-07-14

    Two kinds of lead-free solders, Sn-8Zn-3Bi and Sn-9Zn-lAl, were used to mount passive components onto printed circuit boards via a re-flow soldering process. The samples were stored at 150 deg. C for 200, 400, 600, 800, and 1100 h. The microstructures of the samples after aged at 150 deg. C for various times were characterized using optical microscopy (OM), scanning electron microscopy (SEM), energy dispersive spectrometry (EDS) and the analyzed of solder joint shear strengths. The joint strength between Sn-8Zn-3Bi and Cu pad was about 4.0 {+-} 0.3 kg, while the strength between Sn-9Zn-lAl and Cu pad had values of 2.6 {+-} 0.1 kg. Both kinds of solder joints exhibited reduced strengths with increasing aging times. After aging at 150 deg. C for 1100 h, the joints strengths of Sn-8Zn-3Bi and Sn-9Zn-lAl were 1.8 {+-} 0.3 and 1.7 {+-} 0.3 kg, respectively. Both the Sn-8Zn-3Bi and Sn-9Zn-lAl joints showed brittle fracture behaviors. A flat layer of Cu{sub 5}Zn{sub 8} intermetallic compound (IMC) was formed between Sn-8Zn-3Bi solder and Cu pad after reflow. When the aging time was increased to 400 h, Zn-depletion and formation of Cu{sub 6}Sn{sub 5} IMC were observed in the solders due to the interaction between the tin and zinc compounds. The interaction between Sn-9Zn-lAl solder and Cu pad had similar behavior, however, Cu{sub 6}Sn{sub 5} IMC formed in Sn-9Zn-lAl solder when after aging at 150 deg. C for 600 h. As the aging time increased, both types of solders generated clear IMC spalling layers with large and continuous voids. Those voids substantially decreased the joint strength.

  4. Electrochemical corrosion behaviour of lead-free Sn-8.5 Zn-X Ag-0.1 Al-0.5 Ga solder in 3.5% NaCl solution

    International Nuclear Information System (INIS)

    Mohanty, Udit Surya; Lin, K.-L.

    2005-01-01

    The electrochemical corrosion behaviour of Pb-free Sn-8.5 Zn-X Ag-0.1 Al-0.5 Ga solder in 3.5% NaCl solution was investigated by using potentiodynamic polarization methods, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS) analysis. The results obtained from polarization studies showed that an increase in the Ag content from 0.1 to 1.5 wt% decreased the corrosion current density (I corr ) and shifted the corrosion potential (E corr ) towards more noble values. These changes were also reflected in the linear polarization resistance (LPR), corrosion rate, anodic Tafel slope (b A ) and the cathodic Tafel slope (b c ) values, respectively. Passivation behaviour was noted in the Sn-Zn-X Ag-Al-Ga solders with Ag content > 0.1 wt%. The oxides and hydroxides of zinc were responsible for the formation of passive film. Presence of Ag atoms in the oxide layer also improved the passivation behaviour of solders to a certain extent. X-ray photoelectron spectroscopy revealed that two different oxygen species were formed on the surface films, one was assigned to OH - in Zn(OH) 2 and the other to O 2 - in ZnO. XPS depth profile results revealed that the two species had different depth distribution in the films. SEM and EDX analyses confirmed SnCl 2 as the major corrosion product formed after the electrochemical experiments

  5. Salmonella O48 Serum Resistance is Connected with the Elongation of the Lipopolysaccharide O-Antigen Containing Sialic Acid

    Directory of Open Access Journals (Sweden)

    Aleksandra Pawlak

    2017-09-01

    Full Text Available Complement is one of the most important parts of the innate immune system. Some bacteria can gain resistance against the bactericidal action of complement by decorating their outer cell surface with lipopolysaccharides (LPSs containing a very long O-antigen or with specific outer membrane proteins. Additionally, the presence of sialic acid in the LPS molecules can provide a level of protection for bacteria, likening them to human cells, a phenomenon known as molecular mimicry. Salmonella O48, which contains sialic acid in the O-antigen, is the major cause of reptile-associated salmonellosis, a worldwide public health problem. In this study, we tested the effect of prolonged exposure to human serum on strains from Salmonella serogroup O48, specifically on the O-antigen length. After multiple passages in serum, three out of four tested strains became resistant to serum action. The gas-liquid chromatography/tandem mass spectrometry analysis showed that, for most of the strains, the average length of the LPS O-antigen increased. Thus, we have discovered a link between the resistance of bacterial cells to serum and the elongation of the LPS O-antigen.

  6. Study of interfacial reactions in Sn-3.5Ag-3.0Bi and Sn-8.0Zn-3.0Bi sandwich structure solder joint with Ni(P)/Cu metallization on Cu substrate

    International Nuclear Information System (INIS)

    Sun, Peng; Andersson, Cristina; Wei, Xicheng; Cheng, Zhaonian; Shangguan, Dongkai; Liu, Johan

    2007-01-01

    In this paper, the coupling effect in Sn-3.5Ag-3.0Bi and Sn-8.0Zn-3.0Bi solder joint with sandwich structure by long time reflow soldering was studied. It was found that the interfacial compound at the Cu substrate was binary Cu-Sn compound in Sn-Ag-Bi solder joint and Cu 5 Zn 8 phase in Sn-Zn-Bi solder joint. The thickness of the Cu-Zn compound layer formed at the Cu substrate was greater than or equal to that of Cu-Sn compound layer, although the reflow soldering temperature of Sn-Zn-Bi (240 o C) was lower than that of Sn-Ag-Bi (250 o C). The stable Cu-Zn compound was the absolute preferential phase in the interfacial layer between Sn-Zn-Bi and the Cu substrate. The ternary (Cu, Ni) 6 Sn 5 compound was formed at the Sn-Ag-Bi/Ni(P)-Cu metallization interface, and a complex alloy Sn-Ni-Cu-Zn was formed at the Sn-Zn-Bi/Ni(P)-Cu metallization interface. It was noted that Cu atoms could diffuse from the Cu substrate through the solder matrix to the Ni(P)-Cu metallization within 1 min reflow soldering time for both solder systems, indicating that just 30 s was long enough for Cu to go through 250 μm diffusion length in the Sn-Ag-Bi solder joint at 250 o C. The coupling effect between Ni(P)/Cu metallization and Cu substrate was confirmed as the type of IMCs at Ni(P) layer had been changed from Ni-Sn system to Cu-Sn system apparently by the diffusion effect of Cu atoms. The (Cu, Ni) 6 Sn 5 layer at the Ni(P)/Cu metallization grew significantly and its thickness was even greater than that of the Cu-Sn compound on the opposite side, however the growth of the complex alloy including Sn, Ni, Cu and Zn on the Ni(P)/Cu metallization was suppressed

  7. Assembly of a new inorganic-organic frameworks based on [Sb4Mo12(OH)6O48]10- polyanion

    Science.gov (United States)

    Thabet, Safa; Ayed, Meriem; Ayed, Brahim; Haddad, Amor

    2014-10-01

    A new organic-inorganic hybrid material, (C4N2H7)8[K(H2O)]2[Sb4Mo12(OH)6O48]ṡ16H2O (1) has been isolated by the conventional solution method and characterized by elemental analysis, single-crystal X-ray diffraction, infrared spectroscopy, UV-visible spectroscopies, cyclic voltammetry and TG-DTA analysis. The compound crystallizes in the triclinic space group P - 1 with a = 13.407(6) Å, b = 13.906(2) Å, c = 14.657(7) Å, α = 77.216(9)°, β = 71.284(6)°, γ = 71.312(3)° and Z = 1. The crystal structure exhibits an infinite 1D inorganic structure built from [Sb4Mo12(OH)6O48]10- clusters and potassium cations; adjacent chains are further joined up hydrogen bonding interactions between protonated 2-methylimidazolim cations, water molecules and polyoxoanions to form a 3D supramolecular architecture.

  8. Search for 12 C+ 12 C clustering in 24 Mg ground state

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 88; Issue 2. Search for 12C+12C clustering in 24Mg ground state. B N JOSHI ARUN K JAIN D C BISWAS B V JOHN Y K GUPTA L S DANU R P VIND G K PRAJAPATI S MUKHOPADHYAY A SAXENA. Regular Volume 88 Issue 2 February 2017 Article ID 29 ...

  9. Multi-sensory stimulation in 24-hour dementia care: effects of snoezelen on residents and caregivers.

    NARCIS (Netherlands)

    Weert, J. van; Dulmen, S. van; Bensing, J.

    2011-01-01

    Dementia among nursing home residents is oftenaccompanied by behavioural disturbances and high caredependency. Multi-Sensory Stimulation or snoezelen,integrated in 24-h dementia care, is an approach thatmight improve mood and behaviour of demented elderlyas well as the quality of working life of

  10. Multi-sensory stimulation in 24-hour dementia care: effects of snoezelen on residents and caregivers

    NARCIS (Netherlands)

    van Weert, J.; van Dulmen, S.; Bensing, J.

    2011-01-01

    Dementia among nursing home residents is oftenaccompanied by behavioural disturbances and high caredependency. Multi-Sensory Stimulation or snoezelen,integrated in 24-h dementia care, is an approach thatmight improve mood and behaviour of demented elderlyas well as the quality of working life of

  11. Indoor Air Quality in 24 California Residences Designed as High Performance Green Homes

    OpenAIRE

    Less, Brennan

    2012-01-01

    Today’s high performance green homes are reaching previously unheard of levels of airtightness and are using new materials, technologies and strategies, whose impacts on IAQ cannot be fully determined by past efforts.  This research assessed IAQ in 24 new or deeply retrofitted homes designed to be high performance green buildings in California using pollutant measurements, home inspections, diagnostic testing and occupant surveys.  Measurements included six-day passive samples of nitrogen oxi...

  12. Indoor Air Quality in 24 California Residences Designed as High-Performance Homes

    Energy Technology Data Exchange (ETDEWEB)

    Less, Brennan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mullen, Nasim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Singer, Brett [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Walker, Iain [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-07-01

    Today’s high performance green homes are reaching previously unheard of levels of airtightness and are using new materials, technologies and strategies, whose impacts on Indoor Air Quality (IAQ) cannot be fully anticipated from prior studies. This research study used pollutant measurements, home inspections, diagnostic testing and occupant surveys to assess IAQ in 24 new or deeply retrofitted homes designed to be high performance green buildings in California.

  13. PATTERNS OF THE MAXIMUM RAINFALL AMOUNTS REGISTERED IN 24 HOURS WITHIN THE OLTENIA PLAIN

    Directory of Open Access Journals (Sweden)

    ALINA VLĂDUŢ

    2012-03-01

    Full Text Available Patterns of the maximum rainfall amounts registered in 24 hours within the Oltenia Plain. The present study aims at rendering the main features of the maximum rainfall amounts registered in 24 h within the Oltenia Plain. We used 30-year time series (1980-2009 for seven meteorological stations. Generally, the maximum amounts in 24 h display the same pattern as the monthly mean amounts, namely higher values in the interval May-October. In terms of mean values, the highest amounts are registered in the western and northern extremity of the plain. The maximum values generally exceed 70 mm at all meteorological stations: D.T. Severin, 224 mm, July 1999; Slatina, 104.8 mm, August 2002; Caracal, 92.2 m, July 1991; Bechet, 80.8 mm, July 2006; Craiova, 77.6 mm, April 2003. During the cold season, there was noticed a greater uniformity all over the plain, due to the cyclonic origin of rainfalls compared to the warm season, when thermal convection is quite active and it triggers local showers. In order to better emphasize the peculiarities of this parameter, we have calculated the frequency on different value classes (eight classes, as well as the probability of appearance of different amounts. Thus, it resulted that the highest frequency (25-35% is held by the first two classes of values (0-10 mm; 10.1-20 mm. The lowest frequency is registered in case of the amounts of more than 100 mm, which generally display a probability of occurrence of less than 1% and only in the western and eastern extremities of the plain.

  14. The art of staying tuned in real-time. Remediation in 24.

    Directory of Open Access Journals (Sweden)

    Bo Kampmann Walther

    2003-01-01

    Full Text Available This article examines and discusses current media strategies in 24 Hours. Elements from interface design, computer games, canonized TV-series, reality-TV, on-line multiplayer games, fandom on the web, etc. are all part of the implicit as well as explicit familiarity and subject matter of 24. Thus, 24 becomes a unique case in point of present day remediation and transmediation. While the former plots the actualisation of historic media into contemporary hybrid genres and expressions, the latter paws the way for media forms that continuously and rapidly communicate with each other. Hereby, the study of 24 calls for new and flexible analytical tools and readings of cultural consumption. In addition, the article investigates how such apparently abstract concepts like contingency, conspiracy, and temporality are dramatized in Fox Network's 24.

  15. Giant quadrupole resonance in 24Mg, 27Al, and 28Si

    International Nuclear Information System (INIS)

    Youngblood, D.H.; Rozsa, C.M.; Moss, J.M.; Brown, D.R.; Bronson, J.D.

    1977-01-01

    The giant-resonance region of 24 Mg, 27 Al, and 28 Si was studied by inelastic scattering of 126-MeV α particles. In contrast to results at 96 MeV, considerable clustering of E2 strength was observed for 27 Al at E/sub x/ approx. 20.1 MeV with GAMMA approx. 7.6 MeV exhausting about 35% of the E2 energy weighted sum rule. E2 strength was also located in 24 Mg in two clusters of states at E-bar/sub x/ approx. 18.2, 24.4 MeV; however, contributions from other multipoles cannot be neglected. In 28 Si a multipeaked group was observed at E/sub x/ approx. 19.4 MeV with GAMMA approx. 4 MeV but no L assignment was made. The energy dependence of the cross section for the giant quadrupole resonance was found to be consistent with distorted-wave Born approximation predictions

  16. Gonadotropin determination in 24-h-urine by sensitive LH and FSH radioimmunoassays

    International Nuclear Information System (INIS)

    Raid, A.; Fenske, M.; Koenig, A.

    1979-01-01

    Urinary lutropin (LH) and follitropin (FSH) were precipitated with acetone and measured by specific radioimmunoassays. Recovery experiments with special regard to urinary pH values were done by adding 125 I-labelled LH and FSH to unprocessed urine. At pH 4.5 68.6% of LH and 66.1% of FSH were recovered. Increasing pH values up to 6.0 resulted in a significant recovery loss of 125 I-LH, but not of 125 I-FSH. Immunoreactive FSH concentrations decreased significantly 6 and 48 hours after starting storage at room temperature. In healthy males and females there were found mean LH and FSH concentrations in 24-h-urine which were similar to those reported by others: LH: males: 22.6 IU; cycling females: 17.8 IU; postmenopausal females: 49.1 IU; FSH: males 6.0 IU; cycling females: 15.0 IU; postmenopausal females: 48.5 IU. Because of their high sensitivity and practicability. These radioimmunoassays could be clinically useful approaches in assessment of pituitary and gonadal disorders in human subjects. (author)

  17. Diastolic blood pressure variability in 24 hour-ABPM and outcomes of chronic kidney disease
.

    Science.gov (United States)

    Sahutoglu, Tuncay; Sakaci, Tamer

    2018-04-10

    Blood pressure variability (BPV) has been associated with increased morbidity and mortality. There are a few studies that reported worse outcomes of chronic kidney disease (CKD) with greater visit-to-visit BPV (VVV), but data with ambulatory blood pressure monitoring (ABPM) is scarce. Ambulatory hypertensive CKD (stage 2 - 4) patients (> 18 years old) with complete 24 hours of ABPM study (SpaceLabs), who were followed up between January 2012 and December 2016, were retrospectively analyzed for the baseline characteristics and outcomes of CKD. Coefficient of variation (CV) in diastolic blood pressure (DBP) was used as an index of BPV. Data of 191 patients (mean age 59.7 ± 12.4 years, 54.9% males, 42.1% diabetic, mean eGFR-EPI (Chronic Kidney Disease Epidemiology Collaboration) 51.7 ± 22.0 mL/min/1.73m2, mean follow-up 26.2 ± 10.4 months) were available for the analysis. On multivariate linear regression analysis, greater DBP-CV was associated with slower decline in eGFR-EPI per year (B -0.648, p = 0.000). Likewise, the hazard ratio (HR) for dialysis inception (occurred in 9.4%) was found significantly lower with increasing DBP-CV in unadjusted and fully adjusted Cox models (HR 0.730, 95% CI 0.618 - 0.861, p = 0.000, and HR 0.678, 95% CI 0.526 - 0.874, p = 0.003, respectively). These findings suggest that DBP variability in 24-hour ABPM may be a good prognostic factor for the outcomes of CKD. Further studies are needed to determine the impact of 24-hour ABPM BPV on CKD progression and its differences from VVV.
.

  18. Cobalt Chrome Spinal Constructs Trigger Airport Security Screening in 24% of Pediatric Patients.

    Science.gov (United States)

    Woon, Regina P; Andras, Lindsay M; Barrett, Kody K; Skaggs, David L

    2015-03-01

    Retrospective study. To determine whether pediatric patients undergo additional airport security screening after posterior spinal fusion. Airport security has expanded to include body scanners as well as traditional metal detectors. Families frequently ask whether spinal implants will trigger airport security, but there is limited information on modern implants and screening methods. The researchers conducted a survey of 50 pediatric patients after posterior spinal fusion from 2004 to 2013. Inclusion criteria were posterior instrumentation, pedicle screws for at least 80% of anchors, and at least 1 trip through an American airport after surgery. Charts and radiographs were reviewed for metal type, number of levels fused, number of anchors, and rod diameter. A total of 16% of patients (8 of 50) were detected by body scan or metal detector and all had cobalt chrome (CoCr) rods. No patients with stainless-steel (SS) rods were detected. The CoCr rods triggered additional screening in 24% of children (8 of 33), compared with none of 17 with SS rods (p = .03). For patients with CoCr rods, the detection rate was 18% (5 of 28) by metal detector and 17% (3 of 18) by body scanner. For patients with CoCr rods, there was no significant difference between detection rates and levels fused (p = .30), number of anchors (p = .15), or rod diameter (p = .17). In this series, CoCr constructs were more likely to incur additional airport security compared with more traditional SS constructs. Copyright © 2015 Scoliosis Research Society. Published by Elsevier Inc. All rights reserved.

  19. Parabens in 24 h urine samples of the German Environmental Specimen Bank from 1995 to 2012.

    Science.gov (United States)

    Moos, Rebecca K; Koch, Holger M; Angerer, Jürgen; Apel, Petra; Schröter-Kermani, Christa; Brüning, Thomas; Kolossa-Gehring, Marike

    2015-10-01

    Parabens are widely used as antimicrobial preservatives in personal care and consumer products, food and pharmaceuticals. Due to their ubiquity, humans are constantly exposed to these chemicals. We assessed exposure to nine parabens (methyl-, ethyl-, n- and iso-propyl-, n- and iso-butyl-, benzyl-, pentyl- and heptyl paraben) in the German population from 1995 to 2012 based on 660 24h urine samples from the German Environmental Specimen Bank (ESB) using on-line HPLC coupled to isotope dilution tandem mass spectrometry. The limit of quantification (LOQ) was 0.5 μg/L for all parabens. We detected methyl-, ethyl- and n-propyl paraben in 79-99% of samples, followed by n-butyl paraben in 40% of samples. We infrequently detected iso-butyl-, iso-propyl- and benzyl paraben in 24%, 4% and 1.4% of samples, respectively. Urinary concentrations were highest for methyl paraben (median 39.8 μg/L; 95th percentile 319 μg/L) followed by n-propyl paraben (4.8 μg/L; 95th percentile 74.0 μg/L) and ethyl paraben (2.1 μg/L; 95th percentile 39.1 μg/L). Women had significantly higher urinary levels for all parabens than men, except for benzyl paraben. Samples from the ESB revealed that over the investigation period of nearly 20 years urinary paraben levels remained surprisingly constant; only methyl paraben had a significant increase, for both men and women. We found strong correlations between methyl- and n-propyl paraben and between n- and iso-butyl paraben. These results indicate that parabens are used in combination and arise from common sources of exposure. Urinary excretion factors are needed to extrapolate from individual urinary concentrations to actual doses. Copyright © 2015 Elsevier GmbH. All rights reserved.

  20. Transarterial embolisation of renal arteriovenous malformation: safety and efficacy in 24 patients with follow-up

    International Nuclear Information System (INIS)

    Eom, H.-J.; Shin, J.H.; Cho, Y.J.; Nam, D.H.; Ko, G.-Y.; Yoon, H.-K.

    2015-01-01

    Aim: To evaluate the efficacy and safety of renal artery embolisation (RAE) for renal arteriovenous malformation (AVM) as well as its outcomes. Materials and methods: The technical and clinical success rates, radiological and laboratory findings, and complications of RAE for 31 renal AVMs in 24 patients (M:F=9:15, mean age 46 years) at two separate medical institutions were retrospectively evaluated. Technical success was defined as complete occlusion of feeding arteries with no residual nidus seen on post-treatment angiography. Clinical failure was defined as recurrence of haematuria, presence of AVM on follow-up ultrasound or computed tomography, repeated RAE or surgery for the control of haematuria. Overall clinical success was defined as resolution haematuria or disappearance of AVM on follow-up imaging after single or multiple sessions of RAE. Results: Types of renal AVM were AVM, arterio-venous fistula (AVF) with intranidal aneurysm, and acquired AVF in 19, 1, and 4 patients, respectively. 18 patients (75%) underwent a single session of RAE, while 6 patients (25%) had two or more sessions of RAE. The level of embolisation was feeder, segmental artery, and main renal artery in 28 (90%), 2 (6%), and 1 (4%) procedures, respectively. Coil, n-butyl 2-cyanoacrylate, and polyvinyl alcohol were the most frequently chosen embolic materials and were used in 19, 14, and 8 procedures, respectively. The clinical success rate after initial RAE was 67% (16/24). Overall clinical success rate, including multisession RAE, was 88% (21/24). The technical success rate of 31 procedures was 65% (20/31). Among 11 technical failures in 10 patients, 4 achieved clinical success without additional RAE, 3 underwent second session RAE to achieve clinical success, and 3 patients underwent nephrectomy due to recurrence. Conclusion: RAE is a safe and effective treatment for renal AVM. Technical failure of RAE does not always lead to clinical failure and multiple embolisation sessions may be

  1. Indoor air quality in 24 California residences designed as high-performance homes

    Energy Technology Data Exchange (ETDEWEB)

    Less, Brennan [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Mullen, Nasim [Gap, Inc., San Francisco, CA (United States); Singer, Brett [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States); Walker, Iain [Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

    2015-01-01

    Today’s high performance green homes are reaching previously unheard of levels of airtightness and are using new materials, technologies and strategies, whose impacts on Indoor Air Quality (IAQ) cannot be fully anticipated from prior studies. This research study used pollutant measurements, home inspections, diagnostic testing and occupant surveys to assess IAQ in 24 new or deeply retrofitted homes designed to be high performance green buildings in California. Although the mechanically vented homes were six times as airtight as non-mechanically ventilated homes (medians of 1.1 and 6.1 ACH50, n=11 and n=8, respectively), their use of mechanical ventilation systems and possibly window operation meant their median air exchange rates were almost the same (0.30 versus 0.32 hr-1, n=8 and n=8, respectively). Pollutant levels were also similar in vented and unvented homes. In addition, these similarities were achieved despite numerous observed faults in complex mechanical ventilation systems. More rigorous commissioning is still recommended. Cooking exhaust systems were used inconsistently and several suffered from design flaws. Failure to follow best practices led to IAQ problems in some cases. Ambient nitrogen dioxide standards were exceeded or nearly so in four homes that either used gas ranges with standing pilots, or in Passive House-style homes that used gas cooking burners without venting range hoods. Homes without active particle filtration had particle count concentrations approximately double those in homes with enhanced filtration. The majority of homes reported using low-emitting materials; consistent with this, formaldehyde levels were approximately half those in conventional, new CA homes built before 2008. Emissions of ultrafine particles (with diameters <100 nm) were dramatically lower on induction electric cooktops, compared with either gas or resistance electric models. These results indicate that high performance homes can achieve

  2. Student financial support. An inventory in 24 European countries. Background report for the project on portability of student financial support

    NARCIS (Netherlands)

    Vossensteyn, Johan J.

    2004-01-01

    This report provides a description of the current national systems of student financial support in 24 European countries. It provides information on tuition fees, grants, scholarships, student loans, and indirect student support through students families (family allowances and tax benefits) and

  3. Effects of snoezelen, integrated in 24 h dementia care, on nurse-patient communication during morning care.

    NARCIS (Netherlands)

    Weert, J.C.M. van; Dulmen, A.M. van; Spreeuwenberg, P.M.M.; Ribbe, M.W.; Bensing, J.M.

    2005-01-01

    OBJECTIVE: To investigate the effectiveness of snoezelen, integrated in 24-hour care, on the communication of Certified Nursing Assistants (CNAs) and demented nursing home residents during morning care. METHODS: A quasi-experimental pre- and post-test design was conducted, comparing sic

  4. Surface and canopy fuels vary widely in 24-yr old postfire lodgepole pine forests

    Science.gov (United States)

    Nelson, K. N.; Turner, M.; Romme, W. H.; Tinker, D. B.

    2013-12-01

    Extreme fire seasons have become common in western North America, and the extent of young postfire forests has grown as fire frequency and annual area burned have increased. These young forests will set the stage for future fires, but an assessment of fuel loads in young forests is lacking. The rate of fuel re-accumulation and fuels variability in postfire forest landscapes is needed to anticipate future fire occurrence and behavior in the American West. We studied fuel characteristics in young lodgepole pine forests that regenerated after the 1988 fires in Yellowstone National Park to address two questions: (1) How do surface fuel characteristics change with time-since-fire? (2) How do canopy and surface fuels vary across the Yellowstone landscape 24 years postfire? During summer 2012, we re-measured surface fuels in 11 plots that were established in 1996 (8 yrs post fire), and we measured surface and canopy fuels in 82 stands (each 0.25 ha) distributed across the Yellowstone post-1988 fire landscape. In the remeasured plots, surface fuel loads generally increased over the last 16 years. One-hr fuels did not change between sample dates, but all other fuel classes (i.e., 10-hr, 100-hr, and 1000-hr) increased by a factor of two or three. Within the sample timeframe, variability of fuel loads within stands decreased significantly. The coefficients of variation decreased for all fuel classes by 23% to 67%. Data from the 82 plots revealed that canopy and surface fuels in 24-year-old stands varied tremendously across the Yellowstone landscape. Live tree densities spanned 0 to 344,067 trees ha-1, producing a mean available canopy fuel load of 7.7 Mg ha-1 and a wide range from 0 to 47 Mg ha-1. Total surface fuel loads averaged 130 Mg ha-1 and ranged from 49 to 229 Mg ha-1, of which 90% was in the 1000-hr fuel class. The mass of fine surface fuels (i.e., litter/duff, 1-hr, 10-hr, and herbaceous fuels) and canopy fuels (i.e., foliage and 1-hr branches) were strongly and

  5. Student financial support. An inventory in 24 European countries. Background report for the project on portability of student financial support

    OpenAIRE

    Vossensteyn, Johan J.

    2004-01-01

    This report provides a description of the current national systems of student financial support in 24 European countries. It provides information on tuition fees, grants, scholarships, student loans, and indirect student support through students families (family allowances and tax benefits) and support in kind in the form of subsidies for travel, accommodation, student restaurants etc. It forms a background report for the study on the extent to which student financial support can be used for ...

  6. Testing the relationships between energy consumption, CO2 emissions, and economic growth in 24 African countries: a panel ARDL approach.

    Science.gov (United States)

    Asongu, Simplice; El Montasser, Ghassen; Toumi, Hassen

    2016-04-01

    This study complements existing literature by examining the nexus between energy consumption (EC), CO2 emissions (CE), and economic growth (GDP; gross domestic product) in 24 African countries using a panel autoregressive distributed lag (ARDL) approach. The following findings are established. First, there is a long-run relationship between EC, CE, and GDP. Second, a long-term effect from CE to GDP and EC is apparent, with reciprocal paths. Third, the error correction mechanisms are consistently stable. However, in cases of disequilibrium, only EC can be significantly adjusted to its long-run relationship. Fourth, there is a long-run causality running from GDP and CE to EC. Fifth, we find causality running from either CE or both CE and EC to GDP, and inverse causal paths are observable. Causality from EC to GDP is not strong, which supports the conservative hypothesis. Sixth, the causal direction from EC to GDP remains unobservable in the short term. By contrast, the opposite path is observable. There are also no short-run causalities from GDP, or EC, or EC, and GDP to EC. Policy implications are discussed.

  7. Temporal changes in serum creatine kinase concentration and degree of muscle rigidity in 24 patients with neuroleptic malignant syndrome

    Directory of Open Access Journals (Sweden)

    Nisijima K

    2013-06-01

    Full Text Available Koichi Nisijima, Katutoshi ShiodaDepartment of Psychiatry, Jichi Medical University, Tochigi, JapanAbstract: Neuroleptic malignant syndrome (NMS is a dangerous adverse response to antipsychotic drugs. It is characterized by the four major clinical symptoms of hyperthermia, severe muscle rigidity, autonomic dysfunction, and altered mental state. Serum creatine kinase (CK elevation occurs in over 90% of NMS cases. In the present study, the detailed temporal changes in serum CK and degree of muscle rigidity, and the relationship between CK concentration and degree of muscle rigidity over the time course from fever onset, were evaluated in 24 affected patients. The results showed that serum CK peaked on day 2 after onset of fever and returned to within normal limits at day 12. Mild muscle rigidity was observed before the onset of fever in 17 of 24 cases (71%. Muscle rigidity was gradually exacerbated and worsened until day 4 after onset of fever. These findings confirm physicians' empirical understanding of serum CK concentrations and muscle rigidity in NMS based on data accumulated from numerous patients with the syndrome, and they indicate that serum CK may contribute to the early detection of NMS.Keywords: neuroleptic malignant syndrome, creatine kinase, muscle rigidity

  8. Late language emergence in 24-month-old twins: heritable and increased risk for late language emergence in twins.

    Science.gov (United States)

    Rice, Mabel L; Zubrick, Stephen R; Taylor, Catherine L; Gayán, Javier; Bontempo, Daniel E

    2014-06-01

    This study investigated the etiology of late language emergence (LLE) in 24-month-old twins, considering possible twinning, zygosity, gender, and heritability effects for vocabulary and grammar phenotypes. A population-based sample of 473 twin pairs participated. Multilevel modeling estimated means and variances of vocabulary and grammar phenotypes, controlling for familiality. Heritability was estimated with DeFries-Fulker regression and variance components models to determine effects of heritability, shared environment, and nonshared environment. Twins had lower average language scores than norms for single-born children, with lower average performance for monozygotic than dizygotic twins and for boys than girls, although gender and zygosity did not interact. Gender did not predict LLE. Significant heritability was detected for vocabulary (0.26) and grammar phenotypes (0.52 and 0.43 for boys and girls, respectively) in the full sample and in the sample selected for LLE (0.42 and 0.44). LLE and the appearance of Word Combinations were also significantly heritable (0.22-0.23). The findings revealed an increased likelihood of LLE in twin toddlers compared with single-born children that is modulated by zygosity and gender differences. Heritability estimates are consistent with previous research for vocabulary and add further suggestion of heritable differences in early grammar acquisition.

  9. A theory-driven, longitudinal evaluation of the impact of team training on safety culture in 24 hospitals.

    Science.gov (United States)

    Jones, Katherine J; Skinner, Anne M; High, Robin; Reiter-Palmon, Roni

    2013-05-01

    Effective teamwork facilitates collective learning, which is integral to safety culture. There are no rigorous evaluations of the impact of team training on the four components of safety culture-reporting, just, flexible and learning cultures. We evaluated the impact of a year-long team training programme on safety culture in 24 hospitals using two theoretical frameworks. We used two quasi-experimental designs: a cross-sectional comparison of hospital survey on patient safety culture (HSOPS) results from an intervention group of 24 hospitals to a static group of 13 hospitals and a pre-post comparison of HSOPS results within intervention hospitals. Dependent variables were HSOPS items representing the four components of safety culture; independent variables were derived from items added to the HSOPS that measured the extent of team training, learning and transfer. We used a generalised linear mixed model approach to account for the correlated nature of the data. 59% of 2137 respondents from the intervention group reported receiving team training. Intervention group HSOPS scores were significantly higher than static group scores in three dimensions assessing the flexible and learning components of safety culture. The distribution of the adoption of team behaviours (transfer) varied in the intervention group from 2.8% to 31.0%. Adoption of team behaviours was significantly associated with odds of an individual reacting more positively at reassessment than baseline to nine items reflecting all four components of safety culture. Team training can result in transformational change in safety culture when the work environment supports the transfer of learning to new behaviour.

  10. [Concordance of glomerular filtration rate with creatinine clearance in 24-hour urine and Schwartz and Schwartz updated].

    Science.gov (United States)

    Salazar-Gutiérrez, María Luisa; Ochoa-Ponce, Cristina; Lona-Reyes, Juan Carlos; Gutiérrez-Íñiguez, Sara Ivonne

    Reference methods for the quantification of the glomerular filtration rate (GFR) are difficult to use in clinical practice; formulas for evaluating GFR based on serum creatinine (SCr) and/or creatinine clearance are used. The aim of this study was to quantify the correlation and concordance of GFR with creatinine clearance in 24-hour urine (GFR24) and Schwartz and Schwartz updated formulas. Cross-sectional study involving healthy pediatric patients and with chronic kidney disease (CKD) from 5 to 16.9 years. Linear correlation between GFR 24 and two formulas was evaluated with the Pearson correlation coefficient (r) and intraclass correlation coefficient (ICC). We studied 134 patients, of which 59.7% were male. Mean age was 10.8 years. The average GFR24 was 140.34ml/min/1.73m 2 ; 34.3% (n=46) had GFR <90ml/min/1.73m 2 . Moderate linear correlation between GFR24 and Schwartz (r= 0.63) and Schwartz updated (r= 0.65) formulas was observed. There was good concordance between the GFR24 and Schwartz (ICC= 0.77) and updated Schwartz (ICC= 0.77) formulas. Schwartz classical formula in patients with GFR24 ≥ 90ml/min/1.73m 2 estimated higher values, while Schwartz updated underestimated values. There is moderate correlation and good concordance between the GFR24 and Schwartz and Schwartz updated formulas. The concordance was better in patients with obesity and lower in women, patients with hyperfiltration and normal weight. Copyright © 2016 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

  11. Variation of Enzyme Activities and Metabolite Levels in 24 Arabidopsis Accessions Growing in Carbon-Limited Conditions1[W

    Science.gov (United States)

    Cross, Joanna M.; von Korff, Maria; Altmann, Thomas; Bartzetko, Linda; Sulpice, Ronan; Gibon, Yves; Palacios, Natalia; Stitt, Mark

    2006-01-01

    Our understanding of the interaction of carbon (C) metabolism with nitrogen (N) metabolism and growth is based mainly on studies of responses to environmental treatments, and studies of mutants and transformants. Here, we investigate which metabolic parameters vary and which parameters change in a coordinated manner in 24 genetically diverse Arabidopsis (Arabidopsis thaliana) accessions, grown in C-limited conditions. The accessions were grown in short days, moderate light, and high nitrate, and analyzed for rosette biomass, levels of structural components (protein, chlorophyll), total phenols and major metabolic intermediates (sugars, starch, nitrate, amino acids), and the activities of seven representative enzymes from central C and N metabolism. The largest variation was found for plant weight, reducing sugars, starch at the end of the night, and several enzyme activities. High levels of one sugar correlated with high levels of other sugars and starch, and a trend to increased amino acids, slightly lower nitrate, and higher protein. The activities of enzymes at the interface of C and N metabolism correlated with each other, but were unrelated to carbohydrates, amino acid levels, and total protein. Rosette weight was unrelated or showed a weak negative trend to sugar and amino acid contents at the end of the day in most of the accessions, and was negatively correlated with starch at the end of the night. Rosette weight was positively correlated with several enzyme activities. We propose that growth is not related to the absolute levels of starch, sugars, and amino acids; instead, it is related to flux, which is indicated by the enzymatic capacity to use these central resources. PMID:17085515

  12. The physiological effects of Shinrin-yoku (taking in the forest atmosphere or forest bathing): evidence from field experiments in 24 forests across Japan.

    Science.gov (United States)

    Park, Bum Jin; Tsunetsugu, Yuko; Kasetani, Tamami; Kagawa, Takahide; Miyazaki, Yoshifumi

    2010-01-01

    This paper reviews previous research on the physiological effects of Shinrin-yoku (taking in the forest atmosphere or forest bathing), and presents new results from field experiments conducted in 24 forests across Japan. The term Shinrin-yoku was coined by the Japanese Ministry of Agriculture, Forestry, and Fisheries in 1982, and can be defined as making contact with and taking in the atmosphere of the forest. In order to clarify the physiological effects of Shinrin-yoku, we conducted field experiments in 24 forests across Japan. In each experiment, 12 subjects (280 total; ages 21.7 +/- 1.5 year) walked in and viewed a forest or city area. On the first day, six subjects were sent to a forest area, and the others to a city area. On the second day, each group was sent to the other area as a cross-check. Salivary cortisol, blood pressure, pulse rate, and heart rate variability were used as indices. These indices were measured in the morning at the accommodation facility before breakfast and also both before and after the walking (for 16 +/- 5 min) and viewing (for 14 +/- 2 min). The R-R interval was also measured during the walking and viewing periods. The results show that forest environments promote lower concentrations of cortisol, lower pulse rate, lower blood pressure, greater parasympathetic nerve activity, and lower sympathetic nerve activity than do city environments. These results will contribute to the development of a research field dedicated to forest medicine, which may be used as a strategy for preventive medicine.

  13. Comparison of sodium, potassium, calcium, magnesium, zinc, copper and iron concentrations of elements in 24-h urine and spot urine in hypertensive patients with healthy renal function.

    Science.gov (United States)

    Zhang, Tianjing; Chang, Xiaoyu; Liu, Wanlu; Li, Xiaoxia; Wang, Faxuan; Huang, Liping; Liao, Sha; Liu, Xiuying; Zhang, Yuhong; Zhao, Yi

    2017-12-01

    Sodium, potassium, calcium, magnesium, zinc, copper and iron are associated with the sequela of hypertension. The most reliable method for testing those elements is by collecting 24-h urine samples. However, this is cumbersome and collection of spot urine is more convenient in some circumstance. The aim of this study was to compare the concentrations of different elements in 24-h urine and spot urine. Data was collected from a sub-study of China Salt Substitute and Stroke Study. 240 participants were recruited randomly from 12 villages in two counties in Ningxia, China. Both spot and 24-h urine specimens were collected from each patient. Routine urine test was conducted, and concentration of elements was measured using microwave digestion and Inductively Coupled Plasma-Optical Emission Spectrometry. Partial correlation analysis and Spearman correlation analysis were used to investigate the concentration of different elements and the relationship between 24- h urine and spot urine. A partial correlation in sodium, potassium, calcium, magnesium and iron was found between paired 24-h urine and spot urine samples except copper and zinc: 0.430, 0.426, 0.550, 0.221 and 0.191 respectively. Spot urine can replace 24-h urine for estimating some of the elements in hypertensive patients with normal renal function. Copyright © 2017 Elsevier GmbH. All rights reserved.

  14. Critical study of common conditions of storage of glucocorticoids and catecholamines in 24-h urine collected during resting and exercising conditions.

    Science.gov (United States)

    Gouarne, C; Foury, A; Duclos, M

    2004-10-01

    Except immediate freezing of the samples, no practical method has been validated for preservation of glucocorticoids and catecholamines in 24-h urine collection. Furthermore, the influence of urine storage at bladder temperature during periods of different lengths and the effect of prior exercise on preservation of these hormones in the bladder have not been investigated until now. Ten healthy volunteers collected their urine both after a resting and after an exercise session. Urine was aliquoted into tubes which were stored during 24 h in the presence or in the absence of preservatives and at different temperatures. Two samples were stored either 3 or 9 h at 37 degrees C (bladder temperature) without additive. When collecting 24-h urine samples for glucocorticoids determination, sample can be stored at room temperature during the 24-h collection period without compromising glucocorticoids preservation. When collecting 24-h urine samples for catecholamines determination, samples have to be chilled without preservative during the whole of the collection period. If the samples have to be stored at room temperature, HCl should be used. Moreover, we report for the first time that catecholamines can be degraded in the bladder and therefore that subjects should urinate every 3 h during either a resting or an exercising day.

  15. Improvement in 24-hour bronchodilation and symptom control with aclidinium bromide versus tiotropium and placebo in symptomatic patients with COPD: post hoc analysis of a Phase IIIb study

    Directory of Open Access Journals (Sweden)

    Beier J

    2017-06-01

    Full Text Available Jutta Beier,1 Robert Mroz,2,3 Anne-Marie Kirsten,4 Ferran Chuecos,5 Esther Garcia Gil5 1insaf Respiratory Research Institute, Wiesbaden, Germany; 2Centrum Medycyny Oddechowej, 3Medical University of Białystok, Białystok, Poland; 4Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany; 5AstraZeneca PLC, Barcelona, Spain Background: A previous Phase IIIb study (NCT01462929 in patients with moderate to severe COPD demonstrated that 6 weeks of treatment with aclidinium led to improvements in 24-hour bronchodilation comparable to those with tiotropium, and improvement of symptoms versus placebo. This post hoc analysis was performed to assess the effect of treatment in the symptomatic patient group participating in the study. Methods: Symptomatic patients (defined as those with Evaluating Respiratory Symptoms [E-RS™] in COPD baseline score ≥10 units received aclidinium bromide 400 µg twice daily (BID, tiotropium 18 µg once daily (QD, or placebo, for 6 weeks. Lung function, COPD respiratory symptoms, and incidence of adverse events (AEs were assessed. Results: In all, 277 symptomatic patients were included in this post hoc analysis. Aclidinium and tiotropium treatment improved forced expiratory volume in 1 second (FEV1 from baseline to week 6 at all time points over 24 hours versus placebo. In addition, improvements in FEV1 from baseline during the nighttime period were observed for aclidinium versus tiotropium on day 1 (aclidinium 157 mL, tiotropium 67 mL; P<0.001 and week 6 (aclidinium 153 mL, tiotropium 90 mL; P<0.05. Aclidinium improved trough FEV1 from baseline versus placebo and tiotropium at day 1 (aclidinium 136 mL, tiotropium 68 mL; P<0.05 and week 6 (aclidinium 137 mL, tiotropium 71 mL; P<0.05. Aclidinium also improved early-morning and nighttime symptom severity, limitation of early-morning activities, and E-RS Total and domain scores versus

  16. Landscape variation in tree regeneration and snag fall drive fuel loads in 24-year old post-fire lodgepole pine forests.

    Science.gov (United States)

    Nelson, Kellen N; Turner, Monica G; Romme, William H; Tinker, Daniel B

    2016-12-01

    Escalating wildfire in subalpine forests with stand-replacing fire regimes is increasing the extent of early-seral forests throughout the western USA. Post-fire succession generates the fuel for future fires, but little is known about fuel loads and their variability in young post-fire stands. We sampled fuel profiles in 24-year-old post-fire lodgepole pine (Pinus contorta var. latifolia) stands (n = 82) that regenerated from the 1988 Yellowstone Fires to answer three questions. (1) How do canopy and surface fuel loads vary within and among young lodgepole pine stands? (2) How do canopy and surface fuels vary with pre- and post-fire lodgepole pine stand structure and environmental conditions? (3) How have surface fuels changed between eight and 24 years post-fire? Fuel complexes varied tremendously across the landscape despite having regenerated from the same fires. Available canopy fuel loads and canopy bulk density averaged 8.5 Mg/ha (range 0.0-46.6) and 0.24 kg/m 3 (range: 0.0-2.3), respectively, meeting or exceeding levels in mature lodgepole pine forests. Total surface-fuel loads averaged 123 Mg/ha (range: 43-207), and 88% was in the 1,000-h fuel class. Litter, 1-h, and 10-h surface fuel loads were lower than reported for mature lodgepole pine forests, and 1,000-h fuel loads were similar or greater. Among-plot variation was greater in canopy fuels than surface fuels, and within-plot variation was greater than among-plot variation for nearly all fuels. Post-fire lodgepole pine density was the strongest positive predictor of canopy and fine surface fuel loads. Pre-fire successional stage was the best predictor of 100-h and 1,000-h fuel loads in the post-fire stands and strongly influenced the size and proportion of sound logs (greater when late successional stands had burned) and rotten logs (greater when early successional stands had burned). Our data suggest that 76% of the young post-fire lodgepole pine forests have 1,000-h fuel loads that exceed levels

  17. 3-Amino-1,2,4-triazolium ion in [24(3at)]Cl and [24(3at)]2SnCl6·H2O. Comparative X-ray, vibrational and theoretical studies

    Science.gov (United States)

    Daszkiewicz, Marek; Marchewka, Mariusz K.

    2012-09-01

    Crystal structures of 3-amino-1,2,4-triazolium chloride and bis(3-amino-1,2,4-triazolium) hexachloridostannate monohydrate were determined by means of X-ray single crystal diffraction. The route of protonation of organic molecule and tautomer equilibrium constants for the cationic forms were calculated using B3LYP/6-31G* method. The most stable protonated species is 2,4-H2-3-amino-1,2,4-triazolium ion, 24(3at)+. Very good agreement between theoretical and experimental frequencies was achieved due to very weak interactions existing in studied compounds. Significantly weaker intermolecular interactions are found in [24(3at)]2SnCl6·H2O than in [24(3at)]Cl. The differences in strength of interactions are manifested in red and blue shifts for stretching and bending motions, respectively. PED calculations show that for 24(3at)+ ion the stretching type of motion of two Nringsbnd H bonds is independent, whereas bending is coupled.

  18. [Perceptions and attitudes of public health service dentists in the face of family violence in 24 municipalities in the state of São Paulo, Brazil, 2013-2014].

    Science.gov (United States)

    Garbin, Cléa Adas Saliba; Rovida, Tânia Adas Saliba; Costa, Adriana Alves; Garbin, Artênio José Isper

    2016-01-01

    to describe the perceptions and attitudes of dentists working in Primary Healthcare Units in the face of family violence in 24 municipalities in the interior of São Paulo state, Brazil. this is a descriptive study conducted between July 2013 and July 2014; the study population was comprised of 294 professionals; data were collected through a questionnaire containing objective and subjective questions. 111 dentists took part (37.8%), 67.5% of whom were unaware of existing legislation on cases of violence; 70.0% did not know how to report the occurrence of cases; 55.0% reported not having any responsibility for notification; 85.0% were unaware of the notification form; and 60.0% said they should intervene in cases of family violence. the perceptions and attitudes of dentists have shortcomings in relation to notification of family violence and this hinders early diagnosis of the victims of such violence.

  19. 辽宁省"24节气"气温的气候特征分析%Analysis on the Climatic Characteristics of Temperature in "24 solar terms" in Liaoning Province

    Institute of Scientific and Technical Information of China (English)

    侯亚红; 路爽; 张蕊

    2011-01-01

    [目的]分析辽宁省"24节气"气温的气候特征.[方法]采用辽宁省56个测站1951~2009年的逐日气温资料,统计分析了辽宁近59年"24节气"气温的气候特征.[结果]辽宁24个节气平均气温的时间序列呈准正态分布单峰型,大暑是全年最热的节气,小暑节气次之;小寒是全年最冷的节气,大寒节气次之.辽宁24个节气中的升温幅度最大的是清明节气,气温的节气变量为4.9℃,降温幅度最大是立冬节气,气温的节气变量为- 5.1℃.与气温关系密切的小暑、大暑、小寒、大寒、处暑节气的平均气温有明显的年代际变化特征,且随着时间变化均呈先低后高的趋势.1951~1980年各节气平均气温与1981~2009年的相比,有22个节气平均气温上升,1个节气平均气温持平,仅有1个节气略有下降,节气平均气温升幅是0.66℃.[结论]该研究为气象服务提供科学依据.%[ Objective] The aim was to analyze the climatic characteristics of temperature in 24 "solar terms" in Liaoning Province. [ Method J Based on the daily temperature data from 56 stations in Iiaoning Province from 1951 to 2009, the climatic characteristics of temperature in "24 solar terms" in Liaoning Province in recent 59 years were analyzed. [ Result] The time series of average temperature in "24 solar terms" in Liaoning Province from 1951 to 2009 showed quasi normal distribution, namely single peak type, and Great Heat meant the hottest time within one year, and next came Slight Heat, while Slight Cold was the coldest time within one year, and Great Cold took the second place. A-mong 24 "solar terms" , temperature increase was most obvious on Tomb-sweeping Day, with the increase of 4.9 ℃, while temperature decreased most greatly at the Beginning of Winter, with the decrease of 5.1 ℃. There was obvious decadal variation of average temperature in Slight Heat, Great Heat, Slight Cold, Great Cold and the End of Heat which were closely related to

  20. Acute Low-Volume High-Intensity Interval Exercise and Continuous Moderate-Intensity Exercise Elicit a Similar Improvement in 24-h Glycemic Control in Overweight and Obese Adults.

    Science.gov (United States)

    Parker, Lewan; Shaw, Christopher S; Banting, Lauren; Levinger, Itamar; Hill, Karen M; McAinch, Andrew J; Stepto, Nigel K

    2016-01-01

    Background: Acute exercise reduces postprandial oxidative stress and glycemia; however, the effects of exercise intensity are unclear. We investigated the effect of acute low-volume high-intensity interval-exercise (LV-HIIE) and continuous moderate-intensity exercise (CMIE) on glycemic control and oxidative stress in overweight and obese, inactive adults. Methods: Twenty-seven adults were randomly allocated to perform a single session of LV-HIIE (9 females, 5 males; age: 30 ± 1 years; BMI: 29 ± 1 kg·m -2 ; mean ± SEM) or CMIE (8 females, 5 males; age: 30 ± 2.0; BMI: 30 ± 2.0) 1 h after consumption of a standard breakfast. Plasma redox status, glucose and insulin were measured. Continuous glucose monitoring (CGM) was conducted during the 24-h period before (rest day) and after exercise (exercise day). Results: Plasma thiobarbituric acid reactive substances (TBARS; 29 ±13%, p improvement in 24-h average glucose levels (-5 ± 2%, p improving 24-h glycemic control in overweight and obese adults.

  1. [Lessons and impact of two audits on postpartum hemorrhages in 24 maternity hospitals of the network "Sécurité Naissance - Naître Ensemble" in "Pays-de-la-Loire" area].

    Science.gov (United States)

    Branger, B; Gillard, P; Monrigal, C; Thelu, S; Robidas, E; Viot, S; Descamps, P; Philippe, H-J; Sentilhes, L; Winer, N

    2011-11-01

    The aim of the study is to assess the compliance rate of treatment of postpartum hemorrhage (PPH) according to guidelines developed by the CNGOF within our network by a first audit, and evaluate the impact of this first audit by conducting a second audit. An initial audit of resources and management of postpartum hemorrhage (PPH) was conducted in 2006-2008 in 24 maternity hospitals of the Pays-de-la-Loire. The audit had identified six areas for improvement. A second audit was implemented in 2009-2010 to evaluate the actions of prevention and measure changes in the management of PPH. Two interns have distributed the 24 maternity homes and moved in each hospital to see 10 cases of vaginal delivery (VD) (section "Prevention"), and the last cases of PPH following a VD. The results are in compliance rate compared to the repository of the HAS in 2004. The first audit was conducted on 101 PPH in total. It has allowed us to propose corrective actions to the 24 maternity hospitals: leaf specific monitoring, reporting amounts of blood loss, transfusion on these clinical criteria without waiting for the blood cell counts, indicating more frequent and rapid sulprostone, set for maternity hospitals without surgical skill an agreement with a visceral surgery department, and avoid maternal transfers for PPH. For the second audit, the compliance rate of the preventive aspect was 73% (95: 71-75%) of 239 cases of BA with variations according to maternity from 48 to 93%. Compliance rates according to the criteria were: 99% obstetric consultations, 98% for anesthesia, 92% for hemoglobin, 77% for the group card available in the record, 89% agglutinins, 35% for the notification of the installation of bag, 36% for the notification of the amount of blood lost, 69% for the supervisor within two hours, and 64% for the directed delivery. For component "Support", the overall compliance rate was 81% (95: 79-83%) of 118 PPH AVB, and 85% in the 71 uterine atonies in 21 pregnancies (3 had no HPP

  2. Neutron emission from projectile-like and target-like fragments in the 18O+48Ti reaction at E(18O)=116 MeV

    International Nuclear Information System (INIS)

    Chambon, B.; Drain, D.; Pastor, C.; Dauchy, A.; Giorni, A.; Morand, C.

    1982-07-01

    Angular correlations between neutrons and projectile-like fragments detected near the grazing angle were analysed by assuming two incoherent neutrons sources. One source describes slower neutrons evaporated by target-like fragments in equilibrium. The faster, forward-peaked neutrons originate from a second source strongly correlated with the projectile-like fragments with regards to velocity and direction. In some cases neutron emission may even be attributed to known neutron emitter levels in excited ejectiles

  3. Nuclear propulsion: to go to the moon in 24 hours

    International Nuclear Information System (INIS)

    Freeman, M.

    1999-01-01

    Nuclear propulsion is a necessary step to give to man the opportunity of developing activities in space. This technique enables rockets to go farther, more quickly and to transport more load than the classical chemical propulsion. Space travel requires huge quantities of energy. An equivalent quantity of energy can be extracted from 13 tons of liquid hydrogen-oxygen, from 20 g of uranium (fission), from 0.5 g of deuterium (fusion) and from 0.02 g of anti-hydrogen-hydrogen (annihilation). The concept of nuclear thermal rocket (NTR) is based on an embarked nuclear reactor whose purpose is to heat hydrogen to 3000 K temperature. The thrust can be increased by injecting liquid oxygen in the nozzle to react with supersonic hydrogen. (A.C.)

  4. [Frequency distribution of dibucaine numbers in 24,830 patients].

    Science.gov (United States)

    Pestel, G; Sprenger, H; Rothhammer, A

    2003-06-01

    Atypical cholinesterase prolongs the duration of neuromuscular blocking drugs such as succinylcholine and mivacurium. Measuring the dibucaine number identifies patients who are at risk. This study shows the frequency distribution of dibucaine numbers routinely measured and discusses avoidable clinical problems and economic implications. Dibucaine numbers were measured on a Hitachi 917-analyzer and all dibucaine numbers recorded over a period of 4 years were taken into consideration. Repeat observations were excluded. A total of 24,830 dibucaine numbers were analysed and numbers below 30 were found in 0.07% ( n=18) giving an incidence of 1:1,400. Dibucaine numbers from 30 to 70 were found in 1.23% ( n=306). On the basis of identification of the Dibucaine numbers we could avoid the administration of succinylcholine or mivacurium resulting in a cost reduction of 12,280 Euro offset against the total laboratory costs amounting to 10,470 Euro. An incidence of 1:1,400 of dibucaine numbers below 30 is higher than documented in the literature. Therefore, routine measurement of dibucaine number is a cost-effective method of identifying patients at increased risk of prolonged neuromuscular blockade due to atypical cholinesterase.

  5. Multi-sensory stimulation in 24-hour dementia care

    NARCIS (Netherlands)

    Weert, J.C.M. van

    2004-01-01

    This thesis starts with a review of relevant literature with regard to the effects of psychosocial interventions, including snoezelen, on apathetic, depressed and aggressive behaviour of demented persons. Then, a study with a quasi-experimental pre-test and post-test design is described, comparing

  6. Therapeutic effect of terlipressin combined with albumin in 24 patients with hepatorenal syndrome

    Directory of Open Access Journals (Sweden)

    CHEN Si

    2014-08-01

    Full Text Available ObjectiveTo observe the therapeutic effect of terlipressin combined with albumin in management of patients with hepatorenal syndrome. MethodsA retrospective study enrolling 46 patients with hepatorenal syndrome from May 2011 to August 2013 was conducted, in which 22 patients were allocated to control group, and 24 patients to treatment group. In addition to conventional treatment, albumin was used in control group, and the patients in treatment group were treated with terlipressin plus albumin. Clinical symptoms, urine volume, serum creatinine, urea nitrogen, ascites, and prognosis were observed in the study. The Student′s t test was used for comparison between the two groups, and the chi-square test was used for comparison of rates. ResultsThe treatment group showed significant improvements in clinical symptoms, while the control group did not. In treatment group, urine volume (ml/24 h increased from (758.5±284.9 to (2277.1±704.8 (P<0.01; serum creatinine level (μmol/L dropped from (234.2±87.2 to (126.8±62.2 (P<0.01; urea nitrogen level (mmol/L dropped from (18.1±6.4 to (10.3±4.5 (P<0.01; body weight (kg dropped from (68.1±3.9 to (646±3.9 (P<0.01; abdominal circumference (cm dropped from (95.0±5.1 to (90.8±4.9 (P<0.01. However, the control group showed no significant changes in urine volume, serum creatinine, urea nitrogen, body weight, and abdominal circumference after treatment (P>0.05. There were significant differences in these indices between the two groups after treatment (P<0.05. Significant differences in remission rate and survival rate were observed between the control group and treatment group (P<0.05. ConclusionA combination of terlipressin and albumin has favorable therapeutic effect on hepatorenal syndrome and improves the prognosis of patients with hepatorenal syndrome.

  7. Categorizing with gender: does implicit grammatical gender affect semantic processing in 24-month-old toddlers?

    Science.gov (United States)

    Bobb, Susan C; Mani, Nivedita

    2013-06-01

    The current study investigated the interaction of implicit grammatical gender and semantic category knowledge during object identification. German-learning toddlers (24-month-olds) were presented with picture pairs and heard a noun (without a preceding article) labeling one of the pictures. Labels for target and distracter images either matched or mismatched in grammatical gender and either matched or mismatched in semantic category. When target and distracter overlapped in both semantic and gender information, target recognition was impaired compared with when target and distracter overlapped on only one dimension. Results suggest that by 24 months of age, German-learning toddlers are already forming not only semantic but also grammatical gender categories and that these sources of information are activated, and interact, during object identification. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. Causal Learning from Probabilistic Events in 24-Month-Olds: An Action Measure

    Science.gov (United States)

    Waismeyer, Anna; Meltzoff, Andrew N.; Gopnik, Alison

    2015-01-01

    How do young children learn about causal structure in an uncertain and variable world? We tested whether they can use observed probabilistic information to solve causal learning problems. In two experiments, 24-month-olds observed an adult produce a probabilistic pattern of causal evidence. The toddlers then were given an opportunity to design…

  9. Prediction of wax buildup in 24 inch cold, deep sea oil loading line

    Energy Technology Data Exchange (ETDEWEB)

    Asperger, R.G.; Sattler, R.E.; Tolonen, W.J.; Pitchford, A.C.

    1981-10-01

    When designing pipelines for cold environments, it is important to know how to predict potential problems due to wax deposition on the pipeline's inner surface. The goal of this work was to determine the rate of wax buildup and the maximum, equlibrium wax thickness for a North Sea field loading line. The experimental techniques and results used to evaluate the waxing potential of the crude oil (B) are described. Also, the theoretic model which was used for predicting the maximum wax deposit thickness in the crude oil (B) loading pipeline at controlled temperatures of 40 F (4.4 C) and 100 F (38 C), is illustrated. Included is a recommendation of a procedure for using hot oil at the end of a tanker loading period in order to dewax the crude oil (B) line. This technique would give maximum heating of the pipeline and should be followed by shutting the hot oil into the pipeline at the end of the loading cycle which will provide a hot oil soaking to help soften existing wax. 14 references.

  10. Growth retardation due to idiopathic growth hormone deficiencies: MR findings in 24 patients

    International Nuclear Information System (INIS)

    Ochi, M.; Morikawa, M.; Yoshimoto, M.; Kinoshita, E.; Hayashi, K.

    1992-01-01

    In this study we evaluated the pituitary-hypothalamic abnormalities of ''idiopathic growth hormone (GH) deficiency'' as demonstrated by MR imaging. Twenty-four patients were examined with a 1.5-T unit using spin echo T-1 weighted images. The patients were divided into two groups according to MR findings: those with ectopic posterior pituitary glands (12 patients), and those with normal posterior pituitary glands (12 patients). Ten patients in the former group and four in the latter group had small anterior pituitary glands. All patients in the former group but only four in the latter group had severe GH deficiencies. Multiple hormone deficiencies were found in eight patients in the former group, but in only two in the latter group. It is speculated that perinatal abnormalities can cause posterior pituitary ectopia and that there is a close correlation between breech delivery and the male disadvantage of posterior pituitary ectopia. Half of our patients with ''idiopathic GH deficiency'' had ectopic posterior pituitaries. GH deficiency with posterior pituitary ectopia should no longer be considered idiopathic because organic lesions can now be identified during life. (orig./GD)

  11. Fermentation in 24-well plates is an efficient screening platform for filamentous fungi

    DEFF Research Database (Denmark)

    Linde, Tore; Hansen, Bjørn; Lübeck, Mette

    Conventional citric acid batch-fermentation by filamentous fungi is often linked with large variations in production levels. The most used citric acid batch-fermentation method described in literature is based on Erlenmeyer flasks with cotton-stoppers in a heated shaker. Our preliminary studies...... using Erlenmeyer flasks in sextuplicates showed a relative standard sample deviation of 54 % citric acid produced with the filamentous fungi Aspergillus carbonarius, thereby confirming these large variations. The objective of this study was to propose a different and more reliable screening method...... for citric acid production from filamentous fungi, using A. carbonarius as test organism in a 24 well plate system. The two systems where run simultaneously with only the mechanical parameters as difference between them. All experiments were performed in sextuplicates to be able to give a higher statistical...

  12. Time bound changes (in 24 h) in human sperm motility and level of ...

    African Journals Online (AJOL)

    A detailed sperm motility study for 24 h after collection was done. The level of calcium and magnesium in seminal plasma during this period was also seen to understand the role of these electrolytes on sperm motility. Good care was taken in selection of subjects (young and healthy), collection and pre-physical analysis of ...

  13. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers.

    Science.gov (United States)

    Bandak, M; Jørgensen, N; Juul, A; Lauritsen, J; Kier, M G G; Mortensen, M S; Oturai, P S; Mortensen, J; Hojman, P; Helge, J W; Daugaard, G

    2017-07-01

    Testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to healthy controls. However, because of the fetal etiology of testicular cancer, familial unrelated healthy men might not be an optimal control group. The objective of this study was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39-50) vs. 46 (40-53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7-19). Serum levels of luteinizing hormone and follicle-stimulating hormone were elevated (p ≤ 0.001), while total testosterone, free testosterone, inhibin B and anti-Müllerian hormone were lower (p ≤ 0.001) in testicular cancer survivors than in their biological brothers. The prevalence of metabolic syndrome was similar and apart from HDL-cholesterol, which was lower in testicular cancer survivors (p = 0.01); there were no differences in the individual components of the metabolic syndrome between testicular cancer survivors and their brothers. In conclusion, gonadal function was impaired in testicular cancer survivors, while we did not detect any difference in the prevalence of metabolic syndrome between testicular cancer survivors and their biological brothers. © 2017 American Society of Andrology and European Academy of Andrology.

  14. Cemented total knee replacement in 24 dogs: surgical technique, clinical results, and complications.

    Science.gov (United States)

    Allen, Matthew J; Leone, Kendall A; Lamonte, Kimberly; Townsend, Katy L; Mann, Kenneth A

    2009-07-01

    To characterize the performance of cemented total knee replacement (TKR) in dogs. Preclinical research study. Skeletally mature, male Hounds (25-30 kg; n=24) with no preexisting joint pathology. Dogs had unilateral cemented TKR and were evaluated at 6, 12, 26, or 52 weeks (6 dogs/time point) by radiography, bone density analysis, visual gait assessment, and direct measurement of thigh circumference and stifle joint range of motion as indicators of functional recovery. At study end, the stability of the cemented tibial component was determined by destructive mechanical testing. Joint stability was excellent in 16 dogs (67%) and good in 8 dogs. None of the tibial components had evidence of migration or periprosthetic osteolysis whereas 1 femoral component was loose at 52 weeks. There was an early and significant decrease in tibial bone density, likely because of disuse of the operated limb. Dogs returned to full activity by 12 weeks. The tibial cement-bone interface maintained its strength over 52 weeks. Cement provides stable fixation of the tibial component in canine TKR. Cemented TKR yields adequate clinical function and stifle joint excursion in the dog. Clinical studies are needed to determine the long-term fate of cemented TKR implants, to assess the influence of implant design on implant fixation and wear, and to obtain objective functional data.

  15. Call Home? Mobile Phones and Contacts with Mother in 24 Countries.

    Science.gov (United States)

    Gubernskaya, Zoya; Treas, Judith

    2016-10-01

    This paper explores how the diffusion of mobile phones is associated with communication between adult children and their mothers. The paper analyzes 2001 International Social Survey Program (ISSP) data from 24 countries (N = 12,313) combined with the country-level data on the prevalence of mobile phones. Net of individual-level predictors and country wealth, adult children who resided in countries with high prevalence of mobile phones contacted their mothers more frequently. High prevalence of mobile phones was also associated with larger differences in maternal contact by gender and smaller differences by education. These findings suggest that any impact of new communication technology on intergenerational relations is complex. Although mobile phones point to higher levels of at-a-distance contact with mothers and narrower socio-economic disparities related to access and affordability of communication technology, they are also linked to wider contact disparities following gendered cultural expectations.

  16. Genotype X Environment Interaction for Yield of Pickling Cucumber in 24 U.S. Environments

    Directory of Open Access Journals (Sweden)

    Dia Mahendra

    2018-02-01

    Full Text Available Reliable yield performance is important in cucumber because seed companies prefer to market cultivars adapted to multiple rather than single regions of the U.S. Also, growers benefit by using a cultivar that performs well in many environments. Future performance of cultivars is also important. The objectives of the study were to (i evaluate the yield of cucumber genotypes over successive years and in different locations, and (ii identify cucumber genotypes with high stability for yield. A diverse set of 22 pickling genotypes was evaluated over 3 years (1986, 1987 and 1988 and in 7 locations across the United States. Yield traits were evaluated using once-over harvest and counting the number of fruit that were marketable, culled or oversize. Total yield, marketable yield (total minus culled fruit, early yield (number of oversize fruit, percent culls and fruit per plant were calculated. Data were analyzed with SASGxE and RGxE programs using SAS and R programming languages, respectively. There were strong effects of environment(E as well as genotype(G xE interaction for all traits. Genotypes ‘Regal F1’, ‘Calypso F1’, ‘Carolina F1’, ‘Gy 3’, ‘Gy 14’ and ‘Fremont F1’ had high marketable yield and medium to high stability for all traits. There was an advantage of hybrids over inbreds for trait performance. Hybrids fell into a single cluster with large prediction intervals. Based on the stability statistics and divisive clusters, it appears possible to breed stable cucumber genotypes with high yield. The genotype with highest performance for marketable yield, greatest stability for yield, lowest 1-R2 ratio value (diverse and representative were ‘Marbel F1’ and Gy 14.

  17. Behaviour and development in 24-month-old moderately preterm toddlers

    NARCIS (Netherlands)

    de Jong, Marjanneke; Verhoeven, Marjolein; Lasham, Carole A.; Meijssen, Clemens B.; van Baar, Anneloes L.

    2015-01-01

    OBJECTIVE: Moderately preterm children (gestational age 32-36+6 weeks) are at risk of cognitive and behaviour problems at school age. The aim of this study was to investigate if these problems are already present at the age of 2 years. STUDY DESIGN: Developmental outcome was assessed at 24-months

  18. Mothers' Maximum Drinks Ever Consumed in 24 Hours Predicts Mental Health Problems in Adolescent Offspring

    Science.gov (United States)

    Malone, Stephen M.; McGue, Matt; Iacono, William G.

    2010-01-01

    Background: The maximum number of alcoholic drinks consumed in a single 24-hr period is an alcoholism-related phenotype with both face and empirical validity. It has been associated with severity of withdrawal symptoms and sensitivity to alcohol, genes implicated in alcohol metabolism, and amplitude of a measure of brain activity associated with…

  19. Widespread occurrence of neuro-active pharmaceuticals and metabolites in 24 Minnesota rivers and wastewaters

    Science.gov (United States)

    Writer, Jeffrey; Ferrer, Imma; Barber, Larry B.; Thurman, E. Michael

    2013-01-01

    Concentrations of 17 neuro-active pharmaceuticals and their major metabolites (bupropion, hydroxy-bupropion, erythro-hydrobupropion, threo-hydrobupropion, carbamazepine, 10,11,-dihydro-10,11,-dihydroxycarbamazepine, 10-hydroxy-carbamazepine, citalopram, N-desmethyl-citalopram, fluoxetine, norfluoxetine, gabapentin, lamotrigine, 2-N-glucuronide-lamotrigine, oxcarbazepine, venlafaxine and O-desmethyl-venlafaxine), were measured in treated wastewater and receiving surface waters from 24 locations across Minnesota, USA. The analysis of upstream and downstream sampling sites indicated that the wastewater treatment plants were the major source of the neuro-active pharmaceuticals and associated metabolites in surface waters of Minnesota. Concentrations of parent compound and the associated metabolite varied substantially between treatment plants (concentrations ± standard deviation of the parent compound relative to its major metabolite) as illustrated by the following examples; bupropion and hydrobupropion 700 ± 1000 ng L−1, 2100 ± 1700 ng L−1, carbamazepine and 10-hydroxy-carbamazepine 480 ± 380 ng L−1, 360 ± 400 ng L−1, venlafaxine and O-desmethyl-venlafaxine 1400 ± 1300 ng L−1, 1800 ± 2300 ng L−1. Metabolites of the neuro-active compounds were commonly found at higher or comparable concentrations to the parent compounds in wastewater effluent and the receiving surface water. Neuro-active pharmaceuticals and associated metabolites were detected only sporadically in samples upstream from the effluent outfall. Metabolite to parent ratios were used to evaluate transformation, and we determined that ratios in wastewater were much lower than those reported in urine, indicating that the metabolites are relatively more labile than the parent compounds in the treatment plants and in receiving waters. The widespread occurrence of neuro-active pharmaceuticals and metabolites in Minnesota effluents and surface waters indicate that this is likely a global environmental issue, and further understanding of the environmental fate and impacts of these compounds is warranted.

  20. Involvement of dehydrins in 24-epibrassinolide-induced protection of wheat plants against drought stress.

    Science.gov (United States)

    Shakirova, Farida; Allagulova, Chulpan; Maslennikova, Dilara; Fedorova, Kristina; Yuldashev, Ruslan; Lubyanova, Alsu; Bezrukova, Marina; Avalbaev, Azamat

    2016-11-01

    In this study, we performed a comparative analysis of the physiological and biochemical parameters of wheat cultivars with contrasting drought resistance, drought-resistant Omskaya 35 (O-35) and less drought-resistant Salavat Yulaev (SYu), during 7-day germination under drought stress simulated by 5% mannitol. In addition, we evaluated the effectiveness of pre-sowing seed treatment with 0.4 μM 24-epibrassinolide (EBR) used to increase the resistance of plants of both cultivars to drought stress. It was revealed that mannitol has caused significant changes in the hormonal balance of the plants of both cultivars, associated with abscisic acid (ABA) accumulation and decrease in the contents of indoleacetic acid (IAA) and cytokinins (CKs). It should be noted that more dramatic changes in the content of phytohormones were characteristic for seedlings of SYu cultivar, which was reflected in a stronger growth inhibition of these plants. Pretreatment with EBR mitigated the negative effect of drought on the hormonal status and growth of seedlings during their germination. Furthermore, we found that drought caused accumulation of dehydrin (DHN) proteins, especially of low molecular weight DHNs, whose abundance was 2.5 times greater in O-35 cultivar than in SYu plants. EBR-pretreated plants of both cultivars were characterized by the additional accumulation of DHNs, indicating their involvement in the development of the EBR-induced wheat drought resistance. The use of fluridone allowed us to demonstrate ABA-dependent and ABA-independent pathways of regulation of low molecular mass dehydrins accumulation by EBR in wheat plants of both cultivars under drought conditions. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  1. Epidemiological comparisons of problems and positive qualities reported by adolescents in 24 countries

    DEFF Research Database (Denmark)

    Rescorla, Leslie; Achenbach, Thomas M; Ivanova, Masha Y

    2007-01-01

    In this study, the authors compared ratings of behavioral and emotional problems and positive qualities on the Youth Self-Report (T. M. Achenbach & L. A. Rescorla, 2001) by adolescents in general population samples from 24 countries (N = 27,206). For problem scales, country effect sizes (ESs) ran...

  2. Epidemiological Comparisons of Problems and Positive Qualities Reported by Adolescents in 24 Countries

    Science.gov (United States)

    Rescorla, Leslie; Achenbach, Thomas M.; Ivanova, Masha Y.; Dumenci, Levent; Almqvist, Fredrik; Bilenberg, Niels; Bird, Hector; Broberg, Anders; Dobrean, Anca; Dopfner, Manfred; Erol, Nese; Forns, Maria; Hannesdottir, Helga; Kanbayashi, Yasuko; Lambert, Michael C.; Leung, Patrick; Minaei, Asghar; Mulatu, Mesfin S.; Novik, Torunn S.; Oh, Kyung-Ja; Roussos, Alexandra; Sawyer, Michael; Simsek, Zeynep; Steinhausen, Hans-Christoph; Weintraub, Sheila; Metzke, Christa Winkler; Wolanczyk, Tomasz; Zilber, Nelly; Zukauskiene, Rita; Verhulst, Frank

    2007-01-01

    In this study, the authors compared ratings of behavioral and emotional problems and positive qualities on the Youth Self-Report (T. M. Achenbach & L. A. Rescorla, 2001) by adolescents in general population samples from 24 countries (N = 27,206). For problem scales, country effect sizes (ESs) ranged from 3% to 9%, whereas those for gender and age…

  3. Search for 12 C+ 12 C clustering in 24 Mg ground state

    Indian Academy of Sciences (India)

    In the backdrop of many models, the heavy cluster structure of the ground state of 24 Mg has been probed experimentally for the first time using the heavy cluster knockout reaction 24 Mg( 12 C, 212 C) 12 C in thequasifree scattering kinematic domain. In the ( 12 C, 212 C) reaction, the direct 12 C-knockout cross-section was ...

  4. Retrospective Study on External Canine Limb Prosthesis used in 24 patients

    Directory of Open Access Journals (Sweden)

    Brittany Jean Carr

    2018-03-01

    Full Text Available Objective: The purpose of this retrospective study is to provide data regarding external prosthetic use in small animal patients, evaluate the common complications associated with external prosthetics, and evaluate the outcome of patients using an external prosthetic.Background: The use of external canine limb prosthetics is relatively uncommon in veterinary medicine today.  However, there is growing interest in prosthetics and their clinical application because these devices may offer an alternative to euthanasia in severe cases where full amputation or alternative methods of limb spare are not an option. The goal of the prosthesis is to provide a better quality of life, help prevent further deformation and degeneration of existing joints, decrease leg length discrepancies, increase exercise and activity levels, provide a means to participate in rehabilitation therapy and maintain the ability to perform daily acts of living. To the author’s knowledge, there is no report of external prosthetic use in small animal veterinary medicine, providing the profession with baseline information for use in, not only general practice or referral practice, but also future research.Evidentiary value: This retrospective study provides data regarding external prosthetic use in small animal patients, evaluates the procedures, manufacturing, rehabilitation and common complications associated with external prosthetics, and evaluates the factors that determine a patient’s prosthetic candidacy.Methods: Patients that had an external prosthesis custom manufactured for them at Animal Orthocare, LLC and had a complete medical record were identified for this study.  A client survey was completed via e-mail or telephone to collect further data about the patients, including age, weight, breed, sex, affected limb(s, reason for prosthesis, level of amputation, activities patient could perform with prosthesis in place, prosthetic fit, prosthetic migration (e.g. rotating or slippage, quality of mobility comparing pre-prosthetic mobility to post-prosthetic mobility, prosthetic integrity, client’s post-prosthetic mobility expectations, complications encountered post-prosthetic application, and client’s perspective of patient’s quality of life comparing pre-prosthetic and post-prosthetic placement. Results: Of the 76 patients who were identified for this study and received a survey, survey information was obtained for 24 patients. There were 50% (n=12 forelimbs affected and 50% (n=12 hind limbs affected. Bilateral hind limb prosthesis was found in 8.33% (n=2 of the 24 cases included. Causes for the prosthesis were found to be due to trauma in 37.5% (n=9 of cases, congenital causes in 37.5% (n=9 of cases, neoplasia in 16.66% (n=4 of cases, infectious in 4.17% (n=1 of cases, and unknown in 4.17% (n=1 of cases. Of the 24 patients, 50% (n=12 of clients felt the prosthesis had an excellent fit; 20.83% (n=5 felt the prosthesis had a good fit; 16.67% (n=4 felt the prosthesis had an acceptable fit; 4.17% (n=1 felt the prosthesis had a less than satisfactory fit; lastly, 8.33% (n=2 felt the prosthetic had a poor fit. Of the 24 patients, 91.66% (n=22 were able to stand using the prosthesis; 87.5% (n=21 were able to walk using the prosthesis; 79.17% (n=19 were able to trot using the prosthesis; 70.83% (n=17 were able to climb stairs using the prosthesis; 54.17% (n=13 were able to jump on or off furniture using the prosthesis; 79.17% (n=19 were able to play fetch using the prosthesis.  From these cases, 50% (n=12 of clients felt the patient’s mobility improved post-prosthetic placement. Expectations were met in 70.83% (n=17 of cases; expectations were somewhat met in 4.17% (n=1 of cases; expectations were not met in 25% (n=6 of cases.  Prosthetic migration affected 37.5% (n=9 of cases; residuum sore or infection affected 20.83% (n=5; refusal to use the prosthetic limb occurred in 20.83% (n=5 of cases; concurrent orthopedic disease occurred in 0% of patients; prosthetic failure (breaking occurred in 20.83% (n=5 of cases. Finally, clients were asked to rate the quality of life of patients after prosthetic placement when compared to pre-prosthetic placement on a scale of 1 – 5 (1 = much worse than before, 5 = much better than before. Patients rated a quality of life of 5 were 20.83% (n=5; a rating of 4 was given to 20.83% (n=5; a rating of 3 was given to 45.83% (n=11; a rating of 2 was given to 4.17% (n=1; a rating of 1 was given to 8.33% (n=2. Conclusion: External prosthetics may help improve quality of life and should be considered as an alternative to euthanasia where full amputation or alternative methods of limb spare are not an option.Application: These results should be considered by veterinarians and prosthetists when searching for an alternative to full amputation or other limb spare surgical methods.

  5. Miyoshi-type distal muscular dystrophy - Clinical spectrum in 24 Dutch patients

    NARCIS (Netherlands)

    Linssen, WHJP; Notermans, NC; VanderGraaf, Y; Wokke, JHJ; VanDoorn, PA; Howeler, CJ; Busch, HFM; DeJager, AEJ; DeVisser, M

    1997-01-01

    Miyoshi-type distal muscular dystrophy has now been found to be more frequent outside Japan than was previously thought. We studied 24 Dutch patients with Miyoshi-type distal muscular dystrophy and focused on its clinical expression and natural history, muscle CT-scans and muscle biopsy findings.

  6. Deformation-induced splitting of the monopole giant resonance in 24Mg

    Directory of Open Access Journals (Sweden)

    Kvasil J.

    2016-01-01

    Full Text Available The strong deformation splitting of the isoscalar giant monopole resonance (ISGMR, recently observed in (α, α′ reaction in prolate 24Mg, is analyzed in the framework of the Skyrme quasiparticle randomphase-approximation (QRPA approach with the Skyrme forces SkM*, SVbas and SkPδ. The calculations with these forces give close results and confirm that the low-energy E0-peak is caused by the deformation-induced coupling of ISGMR with the K = 0 branch of the isoscalar giant quadrupole resonance.

  7. Miyoshi-type distal muscular dystrophy. Clinical spectrum in 24 Dutch patients

    NARCIS (Netherlands)

    Linssen, W. H.; Notermans, N. C.; van der Graaf, Y.; Wokke, J. H.; van Doorn, P. A.; Höweler, C. J.; Busch, H. F.; de Jager, A. E.; de Visser, M.

    1997-01-01

    Miyoshi-type distal muscular dystrophy has now been found to be more frequent outside Japan than was previously thought. We studied 24 Dutch patients with Miyoshi-type distal muscular dystrophy and focused on its clinical expression and natural history, muscle CT-scans and muscle biopsy findings.

  8. Miyoshi-type distal muscular dystrophy. Clinical spectrum in 24 Dutch patients

    NARCIS (Netherlands)

    W.H.J.P. Linssen (Wim); N.C. Notermans (Nicolette); Y. van der Graaf (Yolanda); J.H.J. Wokke (John); P.A. van Doorn (Pieter); C.J. Höweler (Chris); H.F.M. Busch (Herman); A.E.J. de Jager (Aeiko); M. de Visser (Marianne)

    1997-01-01

    textabstractMiyoshi-type distal muscular dystrophy has now been found to be more frequent outside Japan than was previously thought. We studied 24 Dutch patients with Miyoshi-type distal muscular dystrophy and focused on its clinical expression and natural history muscle CT-scans and muscle biopsy

  9. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers

    DEFF Research Database (Denmark)

    Bandak, M.; Jorgensen, N.; Juul, A.

    2017-01-01

    ) criteria comprised the main outcome measures of the study. Median age was similar in testicular cancer survivors and their biological brothers [44 years (IQR 39–50) vs. 46 (40–53) years respectively (p = 0.1)]. In testicular cancer survivors, follow-up since treatment was 12 years (7–19). Serum levels...... was to clarify if testicular cancer survivors have impaired gonadal function and increased risk of metabolic syndrome when compared to their biological brothers. A cross-sectional study of testicular cancer survivors (ClinicalTrials.gov number, NCT02240966) was conducted between 2014 and 2016. Of 158 testicular...... cancer survivors included, 24 had a biological brother who accepted to participate in the study. Serum levels of reproductive hormones and prevalence of metabolic syndrome according to International Diabetes Federation Criteria and National Cholesterol Education Program (Adult Treatment Panel III...

  10. Addison's disease presenting with idiopathic intracranial hypertension in 24-year-old woman: a case report

    Directory of Open Access Journals (Sweden)

    Moore Peter

    2010-02-01

    Full Text Available Abstract Introduction Idiopathic intracranial hypertension can rarely be associated with an underlying endocrine disorder such as Cushing's syndrome, hyperthyroidism, or with administration of thyroxine or growth hormone. Though cases of idiopathic intracranial hypertension associated with Addison's disease in children have been reported, there is only one documented case report of this association in adults. We describe a case of an acute adrenal insufficiency precipitated by idiopathic intracranial hypertension in a Caucasian female. Case presentation A 24-year-old Caucasian woman was acutely unwell with a background of several months of generalised fatigue and intermittent headaches. She had unremarkable neurological and systemic examination with a normal computerised tomography and magnetic resonance imaging of the brain. Normal cerebrospinal fluid but increased opening pressure at lumbar puncture suggested intracranial hypertension. A flat short synacthen test and raised level of adrenocorticotrophic hormone were consistent with primary adrenal failure. Conclusion Addison's disease can remain unrecognised until precipitated by acute stress. This case suggests that idiopathic intracranial hypertension can rarely be associated with Addison's disease and present as an acute illness. Idiopathic intracranial hypertension is possibly related to an increase in the levels of arginine vasopressin peptide in serum and cerebrospinal fluid secondary to a glucocorticoid deficient state.

  11. Reducing the variability of antibiotic production in Streptomyces by cultivation in 24-square deepwell plates

    DEFF Research Database (Denmark)

    Siebenberg, S.; Bapat, Prashant Madhusudhan; Eliasson Lantz, Anna

    2010-01-01

    Highly reproducible production values of the aminocoumarin antibiotic novobiocin were achieved by cultivation of a heterologous Streptomyces producer strain in commercially available square deepwell plates consisting of 24 wells of 3 ml culture volume each. Between parallel cultivation batches...

  12. Feline infectious peritonitis with neurologic involvement: clinical and pathological findings in 24 cats

    International Nuclear Information System (INIS)

    Kline, K.L.; Joseph, R.J.; Averill, D.R. Jr.

    1994-01-01

    The medical records of 24 cats with histopathologically diagnosed feline infectious peritonitis involving the nervous system were reviewed. Seventeen cats had historical, clinical, and pathological findings of systemic disease. Twelve cats had focal signs of central nervous system dysfunction. Twelve cats had multifocal signs including seizures, nystagmus, head tilt, vestibular or cerebellar ataxia, paresis, and proprioceptive loss with a preponderance of caudal fossa signs. Computed tomography of the brain revealed hydrocephalus in two cats. Examination of cerebrospinal fluid revealed pyogranulomatous pleocytosis in fivecats; the tap was nonproductive in five cats. Findings on histopathological examination of appropriate tissues included nephritis, hepatitis, and pleuritis. Neuropathological findings included ependymitis, choroid plexitis, meningitis, encephalitis, and myelitis. Hydrocephalus was seen in 18 cats on necropsy

  13. Obtaining liver tridimensional scaffold through the decellularization of rabbit whole liver in 24 hours

    Science.gov (United States)

    Federico, Schliamser; Ayelen, Rinaldi; Romina, Comin; Alba Nelly, Borchert; Adrian, Nari Gustavo; Alicia, Salvatierra Nancy; Mariana Paula, Cid

    2016-04-01

    In the present work, we development a new protocol for liver decellularization in which the hole decellularization was reached over 24 h. Introduction: the availability of transplantable livers is not sufficient to fulfill the current demand for grafts, with the search for therapeutic alternatives having generated different lines of research, one of which is the use of decellularized three-dimensional biological matrices and subsequent cell seeding to obtain a functional organ. Objective: to produce a decellularization protocol from rabbit liver to generate a three-dimensional matrixin which the time period involved didn't pass 24 h. Methods: The decellularization is obtained through the use of water and SDS (0,1-0,3 %), after freezing at -80 degrees, is the best alternative of different physical and/or chemical mechanisms to break down organ cells and leave only the extracellular matriz. After 24 h of retrograde perfusion, a decellularized translucent matrix was generated. To evaluate if the decellularization protocol was successful, with the extracellular matrix being preserved, we carried out histological (light microscopy) and biochemical (DNA quantification) studies. Results: the decellularization process was verified by macroscopic observation of the organ using microscopic observation corroborated the macroscopic results, with the hematoxylin-eosin and Masson staining showing no cells or nuclear material. In addition, the DNA quantification was less than 10% in the decellularized liver compared to control. Finally,the time taken to develop the decellularization protocol was less than 24 hours.

  14. Obtaining liver tridimensional scaffold through the decellularization of rabbit whole liver in 24 hours

    International Nuclear Information System (INIS)

    Federico, Schliamser; Ayelen, Rinaldi; Romina, Comin; Alicia, Salvatierra Nancy; Paula, Cid Mariana; Nelly, Borchert Alba; Adrian, Nari Gustavo

    2016-01-01

    In the present work, we development a new protocol for liver decellularization in which the hole decellularization was reached over 24 h. Introduction: the availability of transplantable livers is not sufficient to fulfill the current demand for grafts, with the search for therapeutic alternatives having generated different lines of research, one of which is the use of decellularized three-dimensional biological matrices and subsequent cell seeding to obtain a functional organ. Objective: to produce a decellularization protocol from rabbit liver to generate a three-dimensional matrixin which the time period involved didn't pass 24 h. Methods: The decellularization is obtained through the use of water and SDS (0,1-0,3 %), after freezing at -80 degrees, is the best alternative of different physical and/or chemical mechanisms to break down organ cells and leave only the extracellular matriz. After 24 h of retrograde perfusion, a decellularized translucent matrix was generated. To evaluate if the decellularization protocol was successful, with the extracellular matrix being preserved, we carried out histological (light microscopy) and biochemical (DNA quantification) studies. Results: the decellularization process was verified by macroscopic observation of the organ using microscopic observation corroborated the macroscopic results, with the hematoxylin-eosin and Masson staining showing no cells or nuclear material. In addition, the DNA quantification was less than 10% in the decellularized liver compared to control. Finally,the time taken to develop the decellularization protocol was less than 24 hours. (paper)

  15. Laypersons may learn basic life support in 24min using a personal resuscitation manikin

    DEFF Research Database (Denmark)

    Isbye, Dan Lou; Rasmussen, Lars Simon; Lippert, Freddy Knudsen

    2006-01-01

    -training. The second group attended a conventional 6 h BLS course (6 HR). After 3 months BLS skills were assessed on a Laerdal ResusciAnne manikin using the Laerdal PC Skill reporting System, and a total score was calculated. RESULTS: There was no significant difference between groups in BLS performance using...... assessed after 3 months, a 24 min DVD-based instruction plus subsequent self-training in BLS appears equally effective compared to a 6h BLS course and hence is more efficient. Udgivelsesdato: 2006-Jun...... and the challenge is to find the most efficient one. AIMS: To compare the efficiency of a 24 min instruction using a DVD-based self-training BLS course combined with a simple, take-home resuscitation manikin to a conventional 6h course for teaching BLS to laypersons. METHODS: In total, 238 laypersons (age 21...

  16. Renewable energy, carbon emissions, and economic growth in 24 Asian countries: evidence from panel cointegration analysis.

    Science.gov (United States)

    Lu, Wen-Cheng

    2017-11-01

    This article aims to investigate the relationship among renewable energy consumption, carbon dioxide (CO 2 ) emissions, and GDP using panel data for 24 Asian countries between 1990 and 2012. Panel cross-sectional dependence tests and unit root test, which considers cross-sectional dependence across countries, are used to ensure that the empirical results are correct. Using the panel cointegration model, the vector error correction model, and the Granger causality test, this paper finds that a long-run equilibrium exists among renewable energy consumption, carbon emission, and GDP. CO 2 emissions have a positive effect on renewable energy consumption in the Philippines, Pakistan, China, Iraq, Yemen, and Saudi Arabia. A 1% increase in GDP will increase renewable energy by 0.64%. Renewable energy is significantly determined by GDP in India, Sri Lanka, the Philippines, Thailand, Turkey, Malaysia, Jordan, United Arab Emirates, Saudi Arabia, and Mongolia. A unidirectional causality runs from GDP to CO 2 emissions, and two bidirectional causal relationships were found between CO 2 emissions and renewable energy consumption and between renewable energy consumption and GDP. The findings can assist governments in curbing pollution from air pollutants, execute energy conservation policy, and reduce unnecessary wastage of energy.

  17. Normal values of iodine - 131 uptake in 24 hours, in Rio Grande do Norte, Brazil

    International Nuclear Information System (INIS)

    Oliveira Filho, T.F. de; Oliveira, C.F.F. de

    Thorough clinical exams on all patients come to the radioisotope Laboratory at UFRN, where carried out attempting to select those patients with thyroids considered to be clinically normal. After wayne tests for hypo and hyperthyroidism were carried out, 100 patients were considered to be fit for the research. All of them had an impalpable and asympitomatic thyroid. Waynes clinical indices were precisely revealed in 93% of cases. It was concluded that the normal values of uptake of 131 I during the 24 hours in RGN varied between 14% and 44% [pt

  18. Normal polarity magnetosubchrons in 24r and the age of the Paleocene-Eocene boundary

    Energy Technology Data Exchange (ETDEWEB)

    Lerbekmo, J.F.; Heaman, L.M.; Baadsgaard, H.; Muehlenbachs, K.; Evans, M.E.; Sweet, A.R. [University of Alberta, Edmonton, AB (Canada)

    2008-07-15

    A late Paleocene to early Eocene sequence of flat-lying continental strata occurs in an area known as Obed Mountain, west-central Alberta. The upper 110 m consist of interbedded fluvial channel sandstones and overbank mudrocks containing five back swamp coal seams. Two coreholes, 3.5 km apart, that extend through the entire coal zone were sampled for magnetostratigraphy and {sup 13}C isotope analysis. Bentonites in the No. 1 (lowest) and No. 5 coal seams and a tuff in the No. 3 coal seam were sampled for U-Pb and (or) Rb-Sr dating of zircon and biotite, respectively. Magnetostratigraphic analysis of 520 samples identified the younger part of chron 25r, the whole of chron 25n and the older half of chron 24r. We find six normal polarity subzones in this part of chron 24r, which we correlate to tiny wiggles 6 to 11 in marine magnetic profiles. Carbon isotope analysis of 14 samples from two cores revealed a negative shift of about 2 parts per thousand peaking near the base of 24r.8r. We interpret this as the carbon isotope excursion (CIE), the base of which is now accepted as defining the Paleocene-Eocene boundary. The thickness of the CIE in the Obed Mountain section implies that it lasted between 210 000 and 254 000 years. Radiometric dates of 58.4 {+-} 0.2, 57.7 {+-} 0.3, and 56.9 {+-} 0.8 Ma are obtained for the No. 1, No. 3, and No. 5 coals, respectively. Combining these with magnetostratigraphy and cyclostratigraphy yields an age of 57.1 {+-} 0.1 Ma for the Paleocene-Eocene boundary.

  19. Disruption of transitional stages in 24-h blood pressure in renal transplant recipients

    Directory of Open Access Journals (Sweden)

    Marcelo E Katz

    2012-03-01

    Full Text Available Patients with kidney replacement exhibit disrupted circadian rhythms. Most studies measuring blood pressure use the dipper/non-dipper classification, which does not consider analysis of transitional stages between low and high blood pressure, confidence intervals nor shifts in the time of peak, while assuming subjective onsets of night and day phases. In order to better understand the nature of daily variation of blood pressure in these patients, we analyzed 24h recordings from 41 renal transplant recipients using the non-symmetrical double-logistic fitting assessment which does not assume abruptness nor symmetry in ascending and descending stages of the blood pressure profile, and a cosine best-fitting regression method (Cosinor. Compared with matched controls, double-logistic fitting showed that the times for most of transitional stages (ascending systolic and descending systolic, diastolic and mean arterial pressure had a wider distribution along the 24 h. The proportion of individuals without daily blood pressure rhythm in the transplanted group was larger only for systolic arterial pressure, and the amplitude showed no significant difference. Furthermore, the transplant recipient group had a less pronounced slope in descending systolic and ascending mean blood pressure. Cosinor analysis confirmed the phase related changes, showing a wider distribution of times of peak (acrophases. We conclude that daily disruptions in renal transplant recipients can be explained not only by absence in diurnal variation, but also in changes in waveform-related parameters of the rhythm, and that distortions in the phase of the rhythm are the most consistent finding for the patients.

  20. Nuclear propulsion: to go to the moon in 24 hours; Propulsion nucleaire: aller sur la lune en 24 heures

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, M

    1999-10-01

    Nuclear propulsion is a necessary step to give to man the opportunity of developing activities in space. This technique enables rockets to go farther, more quickly and to transport more load than the classical chemical propulsion. Space travel requires huge quantities of energy. An equivalent quantity of energy can be extracted from 13 tons of liquid hydrogen-oxygen, from 20 g of uranium (fission), from 0.5 g of deuterium (fusion) and from 0.02 g of anti-hydrogen-hydrogen (annihilation). The concept of nuclear thermal rocket (NTR) is based on an embarked nuclear reactor whose purpose is to heat hydrogen to 3000 K temperature. The thrust can be increased by injecting liquid oxygen in the nozzle to react with supersonic hydrogen. (A.C.)

  1. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs.

    Science.gov (United States)

    Urfer, Silvan R; Kaeberlein, Tammi L; Mailheau, Susan; Bergman, Philip J; Creevy, Kate E; Promislow, Daniel E L; Kaeberlein, Matt

    2017-04-01

    Age is the single greatest risk factor for most causes of morbidity and mortality in humans and their companion animals. As opposed to other model organisms used to study aging, dogs share the human environment, are subject to similar risk factors, receive comparable medical care, and develop many of the same age-related diseases humans do. In this study, 24 middle-aged healthy dogs received either placebo or a non-immunosuppressive dose of rapamycin for 10 weeks. All dogs received clinical and hematological exams before, during, and after the trial and echocardiography before and after the trial. Our results showed no clinical side effects in the rapamycin-treated group compared to dogs receiving the placebo. Echocardiography suggested improvement in both diastolic and systolic age-related measures of heart function (E/A ratio, fractional shortening, and ejection fraction) in the rapamycin-treated dogs. Hematological values remained within the normal range for all parameters studied; however, the mean corpuscular volume (MCV) was decreased in rapamycin-treated dogs. Based on these results, we will test rapamycin on a larger dog cohort for a longer period of time in order to validate its effects on cardiac function and to determine whether it can significantly improve healthspan and reduce mortality in companion dogs.

  2. The Great Recession, Adolescent Smoking, and Smoking Inequalities: What Role Does Youth Unemployment Play in 24 European Countries?

    Science.gov (United States)

    Rathmann, Katharina; Pförtner, Timo-Kolja; Elgar, Frank J; Hurrelmann, Klaus; Richter, Matthias

    2017-11-01

    Conflicting evidence has been reported on smoking behavior among adults during times of economic downturn. No study has yet investigated young people's smoking and inequalities in smoking during economic recessions. This study examines the association between country-level youth unemployment due to the economic recession and adolescent smoking and smoking inequalities in Europe. The WHO collaborative "Health Behaviour in School-aged Children" study in 2009/2010 included 15-year-old adolescents from 24 European countries (N = 43 093). Socioeconomic position (SEP) was measured by the Family Affluence Scale. Logistic multilevel models were conducted. The absolute rate of youth unemployment in 2010 (during the recession) and the relative change rate in youth unemployment (2005/2006-2009/2010) were regressed on smoking and SEP inequalities in smoking in 2010, respectively. Youth unemployment rates were not significantly associated with overall smoking in adolescents. A higher absolute youth unemployment rate in 2010 related to lower likelihoods of smoking among middle (OR: 0.99; 95% CI: 0.98-0.99) and low affluent adolescents (OR: 0.99; 95% CI: 0.98-0.99) compared to high affluent adolescents. In contrast, an increase in youth unemployment (2005/2006-2009/2010) was not associated with overall likelihoods of smoking and inequalities in smoking. Our findings indicate that an increase in youth unemployment was not related to smoking and smoking inequalities. However, higher absolute levels of youth unemployment are related to lower likelihoods of smoking in lower SEP adolescents. Thus, smoking among vulnerable groups is more linked to the overall insecure circumstances and the affordability of cigarettes rather than to the economic recession itself. Economic recessions have often led to increases in adult and youth unemployment rates. Conflicting evidence has been reported on smoking behavior among adults during times of economic downturn. This study examines for the first time the impact of the economic recession on young people's smoking and socioeconomic inequalities in smoking. Findings highlight that rather than an increase in youth unemployment, the overall country-level youth unemployment rate is related to young people's tobacco use and particularly to lower odds in smoking among less affluent adolescents across Europe, a finding which is likely to be linked to the affordability of tobacco use. © The Author 2016. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Reference intervals for stone risk factors in 24-h urine among healthy adults of the Han population in China.

    Science.gov (United States)

    Mai, Zanlin; Li, Xiaoxia; Cui, Zelin; Wu, Wenqi; Liu, Yongda; Ou, Lili; Liang, Yueping; Zhao, Zhijian; Liu, Yang; Mai, Xing; Zhu, Wei; Zhang, Tao; Cai, Chao; Yang, Houmeng; Zeng, Guohua

    2018-03-28

    The aim of the study was to establish reference intervals for 24-h urinary stone risk factors in the healthy Chinese Han population. From May 2013 to July 2014, we collected and analyzed 24-h urine samples from healthy adult Han population during a cross-sectional study across China. The protocol for analysis of 24-h urine included volume, pH, oxalate, citrate, sodium, potassium, chloride, calcium, phosphorous, creatinine, urate, magnesium, the ion activity products of calcium oxalate (AP(CaOx) indexs) and calcium phosphate (AP(CaP) indexs). We calculated the reference intervals according to the Clinical and Laboratory Standards Institute (CLSI) 2008 guidelines and compared them with those recorded in other studies. A total of 132 male and 123 female healthy subjects with a mean (SD, range) age of 52.4 (15.2, 19-89) years were eligible in the final analysis. Men had higher 24-h excretion of creatinine, calcium, urate and phosphorus and lower levels of citrate, magnesium, chloride, sodium and potassium than women. AP(CaOx) indexs and AP(CaP) indexs were significantly higher among men than women. When urinary findings were compared with the reference intervals, most of our data showed a high abnormality rate, especially for creatinine, calcium, citrate, magnesium, chloride, sodium and potassium. The present study revealed the normal metabolic status for stone risk factors of the Chinese Han population. It is therefore necessary for each country or region to define their own reference intervals for comparison of stone risk factors between patients and healthy subjects.

  4. Effects of para-aminobenzoic acid (PABA) form and administration mode on PABA recovery in 24-hour urine collections.

    Science.gov (United States)

    Sharma, Rashmi S; Joy, Raechel C; Boushey, Carol J; Ferruzzi, Mario G; Leonov, Alexei P; McCrory, Megan A

    2014-03-01

    Para-aminobenzoic acid (PABA) has long been used as an objective measure to assess completeness of 24-hour urine collections. However, pharmaceutical-grade PABA for human ingestion is not available in the United States. An alternative, the potassium salt of PABA, aminobenzoate potassium, can be obtained for clinical use, although it has not yet been validated in this role. Both PABA and aminobenzoate potassium can be directly ingested in their tablet or capsule forms or added to food before consumption. Our aim was to investigate the effect of form (PABA vs aminobenzoate potassium) and administration mode (directly ingested as a tablet/capsule vs added to food) on urinary PABA recovery levels. Twenty healthy participants underwent 3 test days separated by two 24-hour wash-out periods. Three test conditions, one on each test day, were investigated in randomized order: PABA tablet, aminobenzoate potassium capsule, and PABA or aminobenzoate potassium in food. Ingestion of each dose was supervised and participants performed the 24-hour urine collections while free-living. The 24-hour urine collections were analyzed for PABA recovery (%R) levels using a colorimetric assay. Recoveries 85% to 110% were deemed complete and those >110% were reanalyzed by high pressure liquid chromatography and mass spectrometry. Only complete collections (>85%R) were included in analyses. The recovery for the PABA tablet, aminobenzoate potassium capsule, and PABA/aminobenzoate potassium in food were similar at 98.8%R±2.0%R, 95.1%R±2.3%R, and 93.2%R±2.1%R, respectively, and did not differ significantly. These results suggest that aminobenzoate potassium may be used as an alternative to PABA for assessing the completeness of 24-hour urine collections and to track compliance with consuming provided diets in community-dwelling studies. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  5. Disturbances of the sarcoplasmic reticulum and transverse tubular system in 24-h electrostimulated fast-twitch skeletal muscle

    DEFF Research Database (Denmark)

    Frías, J A; Cadefau, J A; Prats, C

    2005-01-01

    Chronic low-frequency stimulation of rabbit tibialis anterior muscle over a 24-h period induces a conspicuous loss of isometric tension that is unrelated to muscle energy metabolism (J.A. Cadefau, J. Parra, R. Cusso, G. Heine, D. Pette, Responses of fatigable and fatigue-resistant fibres of rabbit...... muscle to low-frequency stimulation, Pflugers Arch. 424 (1993) 529-537). To assess the involvement of sarcoplasmic reticulum and transverse tubular system in this force impairment, we isolated microsomal fractions from stimulated and control (contralateral, unstimulated) muscles on discontinuous sucrose...... of muscles stimulated for 24 h underwent acute changes in the pattern of protein bands. First, light fractions from longitudinal sarcoplasmic reticulum, enriched in Ca2+-ATPase activity, R1 and R2, were greatly reduced (67% and 51%, respectively); this reduction was reflected in protein yield of crude...

  6. Reaction mechanisms in 24.3 MeV/nucleon 238U induced reactions through a comprehensive study of fission

    International Nuclear Information System (INIS)

    Chbihi, A.; Galin; Guerreau, D.; Lewitowicz, M.; Morjean, M.; Pouthas, J.; Piasecki, E.; Kordyasz, A.; Iwanicki, J.; Jastrzebski, J.; Pienkowski, L.; Crema, E.; Gatty, B.; Jacquet, D.; Muchorowska, M.

    1994-01-01

    Nuclear reaction mechanisms for system characterized by very different asymmetries (U+C, Si, Ni, Au) have been investigated at 24.3 MeV/nucleon, using as observables both the fission products and the neutron multiplicity. It is clearly observed that the fusion process-whatever its completeness- can only occur with rather light target nuclei, indicating the persistence of potential energy effects much above the interaction barrier. (authors). 22 refs., 1 fig

  7. Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015.

    Science.gov (United States)

    Cole, Michelle J; Spiteri, Gianfranco; Jacobsson, Susanne; Woodford, Neil; Tripodo, Francesco; Amato-Gauci, Andrew J; Unemo, Magnus

    2017-09-11

    Surveillance of Neisseria gonorrhoeae antimicrobial susceptibility in Europe is performed through the European Gonococcal Antimicrobial Surveillance Programme (Euro-GASP), which additionally provides data to inform the European gonorrhoea treatment guideline; currently recommending ceftriaxone 500 mg plus azithromycin 2 g as first-line therapy. We present antimicrobial susceptibility data from 24 European countries in 2015, linked to epidemiological data of patients, and compare the results to Euro-GASP data from previous years. Antimicrobial susceptibility testing by MIC gradient strips or agar dilution methodology was performed on 2134 N. gonorrhoeae isolates and interpreted using EUCAST breakpoints. Patient variables associated with resistance were established using logistic regression to estimate odds ratios (ORs). In 2015, 1.7% of isolates were cefixime resistant compared to 2.0% in 2014. Ceftriaxone resistance was detected in only one (0.05%) isolate in 2015, compared with five (0.2%) in 2014. Azithromycin resistance was detected in 7.1% of isolates in 2015 (7.9% in 2014), and five (0.2%) isolates displayed high-level azithromycin resistance (MIC ≥ 256 mg/L) compared with one (0.05%) in 2014. Ciprofloxacin resistance remained high (49.4%, vs. 50.7% in 2014). Cefixime resistance significantly increased among heterosexual males (4.1% vs. 1.7% in 2014), which was mainly attributable to data from two countries with high cefixime resistance (~11%), however rates among men-who-have-sex-with-men (MSM) and females continued to decline to 0.5% and 1%, respectively. Azithromycin resistance in MSM and heterosexual males was higher (both 8.1%) than in females (4.9% vs. 2.2% in 2014). The association between azithromycin resistance and previous gonorrhoea infection, observed in 2014, continued in 2015 (OR 2.1, CI 1.2-3.5, p resistance and low overall resistance to ceftriaxone and cefixime. The low cephalosporin resistance may be attributable to the effectiveness of the currently recommended first-line dual antimicrobial therapy; however the high azithromycin resistance threatens the effectiveness of this therapeutic regimen. Whether the global use of azithromycin in mono- or dual antimicrobial therapy of gonorrhoea is contributing to the global increases in azithromycin resistance remains to be elucidated. The increasing cefixime resistance in heterosexual males also needs close monitoring.

  8. Atrazine is not readily mineralised in 24 temperate soils regardless of pre-exposure to triazine herbicides

    International Nuclear Information System (INIS)

    Glaesner, Nadia; Baelum, Jacob; Strobel, Bjarne W.; Jacobsen, Carsten S.

    2010-01-01

    Mineralisation of atrazine in soil has been shown to depend on previous exposure of the herbicide. In this study, 24 Danish soils were collected and screened for potential to mineralise atrazine. Six soils were chosen, because they had never been exposed to atrazine, whereas 18 soils were chosen because of their history of application of atrazine or the related compound terbuthylazine. None of the 24 soils revealed a mineralisation potential of more than 4% of the added atrazine within a 60 day timeframe. In an atrazine adapted French soil, we found 60% mineralisation of atrazine in 30 days. Cattle manure was applied in order to boost the microbial activity, and a 2-3% increase in the atrazine mineralisation was found in some of the temperate soils, while in the highly adapted French soil it caused a 5% reduction. - The study highlights that pre-exposure of soils to triazine herbicides do not result in rapid mineralization in temperate soils.

  9. Inferring catchment precipitation by doing hydrology backward : A test in 24 small and mesoscale catchments in Luxembourg

    NARCIS (Netherlands)

    Krier, R.; Matgen, P.; Goergen, K.; Pfister, L.; Hoffmann, L.; Kirchner, J.W.; Uhlenbrook, S.; Savenije, H.H.G.

    2012-01-01

    The complexity of hydrological systems and the necessary simplification of models describing these systems remain major challenges in hydrological modeling. Kirchner's (2009) approach of inferring rainfall and evaporation from discharge fluctuations by “doing hydrology backward” is based on the

  10. Reduction in 24-Hour Plasma Testosterone Levels in Subjects Who Showered 15 or 30 Minutes After Application of Testosterone Gel

    NARCIS (Netherlands)

    de Ronde, W.; Vogel, S.; Bui, H.N.; Heijboer, A.C.

    2011-01-01

    Study Objective. To investigate whether showering, to prevent the involuntary transfer of testosterone to others through skin contact, either 15 or 30 minutes after application of testosterone gel would significantly affect plasma testosterone levels. Design. Prospective 3-way crossover trial.

  11. Gender specific trends in alcohol use: cross-cultural comparisons from 1998 to 2006 in 24 countries and regions

    NARCIS (Netherlands)

    Simons-Morton, B.; Farhat, T.; Bogt, T.F.M. ter; Hublet, A.; Kuntsche, E.N.; Gabhainn, S.N.; Godeau, E.; Kokkevi, A.

    2009-01-01

    Objective: To examine trends in the prevalence of monthly alcohol use and lifetime drunkenness among 15 year olds in 20 European countries, the Russian Federation, Israel, the United States of America, and Canada. Methods: Alcohol use prevalence and drunkenness were assessed in the Health Behavior

  12. No consistent effects of prenatal or neonatal exposure to Spanish flu on late-life mortality in 24 developed countries

    DEFF Research Database (Denmark)

    Cohen, Alan; Tillinghast, J; Canudas-Romo, V

    2010-01-01

    We test the effects of early life exposure to disease on later health by looking for differences in late-life mortality in cohorts born around the 1918-1919 flu pandemic using data from the Human Mortality Database for 24 countries. After controlling for age, period, and sex effects, residual...

  13. Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis.

    Science.gov (United States)

    Crawford, A H; Stoll, A L; Sanchez-Masian, D; Shea, A; Michaels, J; Fraser, A R; Beltran, E

    2017-09-01

    Feline infectious peritonitis (FIP) is the most common infectious central nervous system (CNS) disease in the cat and is invariably fatal. Improved means of antemortem diagnosis is required to facilitate clinical decision making. Information regarding the magnetic resonance imaging (MRI) findings of neurologic FIP currently is limited, resulting in the need for better descriptions to optimize its use as a diagnostic tool. To describe the clinicopathologic features and MRI findings in cases of confirmed neurologic FIP. Twenty-four client-owned cats with histopathologic confirmation of neurologic FIP. Archived records from 5 institutions were retrospectively reviewed to identify cases with confirmed neurologic FIP that had undergone antemortem MRI of the CNS. Signalment, clinicopathologic, MRI, and histopathologic findings were evaluated. Three distinct clinical syndromes were identified: T3-L3 myelopathy (3), central vestibular syndrome (7), and multifocal CNS disease (14). Magnetic resonance imaging abnormalities were detected in all cases, including meningeal contrast enhancement (22), ependymal contrast enhancement (20), ventriculomegaly (20), syringomyelia (17), and foramen magnum herniation (14). Cerebrospinal fluid was analysed in 11 cases; all demonstrated a marked increase in total protein concentration and total nucleated cell count. All 24 cats were euthanized with a median survival time of 14 days (range, 2-115) from onset of clinical signs. Histopathologic analysis identified perivascular pyogranulomatous infiltrates, lymphoplasmacytic infiltrates, or both affecting the leptomeninges (16), choroid plexuses (16), and periventricular parenchyma (13). Magnetic resonance imaging is a sensitive means of detecting neurologic FIP, particularly in combination with a compatible signalment, clinical presentation, and CSF analysis. Copyright © 2017 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine.

  14. An enhanced postnatal autoimmune profile in 24 week-old C57BL/6 mice developmentally exposed to TCDD

    International Nuclear Information System (INIS)

    Mustafa, A.; Holladay, S.D.; Goff, M.; Witonsky, S.G.; Kerr, R.; Reilly, C.M.; Sponenberg, D.P.; Gogal, R.M.

    2008-01-01

    Developmental exposure of mice to the environmental contaminant and AhR agonist, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), causes persistent postnatal suppression of T cell-mediated immune responses. The extent to which prenatal TCDD may induce or exacerbate postnatal autoimmune disease remains unknown. In the present study, time-pregnant high affinity AhR C57BL/6 mice received a single oral administration of 0, 2.5, or 5 μg/kg TCDD on gestation day (gd) 12. Offspring of these mice (n = 5/gender/treatment) were evaluated at 24 weeks-of-age and showed considerable immune dysregulation that was often gender-specific. Decreased thymic weight and percentages of CD4 + CD8 + thymocytes, and increased CD4 + CD8 - thymocytes, were present in the female but not male offspring. Males but not females showed decreased CD4 - CD8 + T cells, and increased Vβ3 + and Vβ17a + T cells, in the spleen. Males but not females also showed increased percentages of bone marrow CD24 - B220 + B cell progenitors. Antibody titers to dsDNA, ssDNA and cardiolipin displayed increasing trends in both male and female mice, reaching significance for anti-dsDNA in both genders and for ssDNA in males at 5 μg/kg TCDD. Immunofluorescent staining of IgG and C3 deposition in kidney glomeruli increased in both genders of prenatal TCDD-exposed mice, suggestive of early stages of autoimmune glomerulonephritis. Collectively, these results show that exposure to TCDD during immune system development causes persistent humoral immune dysregulation as well as altered cell-mediated responses, and induces an adult profile of changes suggestive of increased risk for autoimmune disease

  15. No consistent effects of prenatal or neonatal exposure to Spanish flu on late-life mortality in 24 developed countries

    Directory of Open Access Journals (Sweden)

    Alan Cohen

    2010-04-01

    Full Text Available We test the effects of early life exposure to disease on later health by looking for differences in late-life mortality in cohorts born around the 1918-1919 flu pandemic using data from the Human Mortality Database for 24 countries. After controlling for age, period, and sex effects, residual mortality rates did not differ systematically for flu cohorts relative to surrounding cohorts. We calculate at most a 20-day reduction in life expectancy for flu cohorts; likely values are much smaller. Estimates of influenza incidence during the pandemic suggest that exposure was high enough for this to be a robust negative result.

  16. The Cause of Unexpected Acute Abdomen and Intra-Abdominal Hemorrhage in 24-Week Pregnant Woman: Bochdalek Hernia

    Directory of Open Access Journals (Sweden)

    Yavuz Savas Koca

    2016-01-01

    Full Text Available Bochdalek hernia (BH is the most common type of congenital diaphragm hernia and is rarely seen in adults. In adult patients, BH often remains asymptomatic or presents with nondiagnostic symptoms and may lead to complications, though rarely. The necrosis and perforations occurring in the hernia may lead to mortality. In this report, we present a 34-year-old pregnant woman at 24 gestational weeks who presented with Bochdalek hernia causing gastric volvulus associated with perforation and intra-abdominal hemorrhage associated with splenic rupture.

  17. Institution-to-Institution Mentoring to Build Capacity in 24 Local US Health Departments: Best Practices and Lessons Learned

    OpenAIRE

    Veatch, Maggie; Goldstein, Gail P.; Sacks, Rachel; Lent, Megan; Van Wye, Gretchen

    2014-01-01

    Introduction Institutional mentoring may be a useful capacity-building model to support local health departments facing public health challenges. The New York City Department of Health and Mental Hygiene conducted a qualitative evaluation of an institutional mentoring program designed to increase capacity of health departments seeking to address chronic disease prevention. The mentoring program included 2 program models, a one-to-one model and a collaborative model, developed and implemented ...

  18. Observations on self-incineration characteristics in 24 years (1993-2016) of autopsies in the city of Milan.

    Science.gov (United States)

    Amadasi, Alberto; Boracchi, Michele; Gentile, Guendalina; Maciocco, Francesca; Maghin, Francesca; Zoja, Riccardo

    2018-01-01

    Self-incineration is one of the most dramatic and lethal suicide methods. It is rarely reported in Western countries and is more frequent in developing regions. We illustrate the forensic cases of self-immolation occurring over 24 years in the city of Milan, Italy, highlighting the main issues of such a complex and rare suicide. We selected 33 cases of self-incineration among 23,417 autopsies (4022 suicides) performed at the Department of Legal Medicine of the University of Milan over a period of 24 years (1993-2016). Several parameters were included and analysed: gender and age of the victims, pathological history, previous suicide intentions/attempts, duration of burning, place of death or discovery of the corpse, circumstantial data of fatal events and autopsy findings, with particular attention to thermal injuries. Self-incineration was found in 0.8% of total suicides and 0.14% of total autopsies. One of these cases involved a complex modality (association with plastic-bag suffocation). The typical characteristics of the victim were an Italian man with psychiatric illness, frequently moved by passion, existential discomfort and economic problems. During the 24-year period, the number of cases of self-incineration progressively reduced. This study provides a general overview in one of the biggest metropolitan Italian areas and is one of the few works performed on this topic. It may be helpful in understanding and studying such an unusual manner of suicide.

  19. Measurement of the polarization parameter in 24 GeV/c pp elastic scattering at large momentum transfers

    CERN Document Server

    Antille, J; Dick, Louis; Gonidec, A; Kuroda, K; Kyberd, P; Michalowicz, A; Perret-Gallix, D; Salmon, G L; Werlen, M

    1981-01-01

    A measurement of the polarization parameter P/sub 0/ in pp elastic scattering has been made 24 GeV/c over the range of momentum transfer squared 0.7< mod t mod <5.0 (GeV/c)/sup 2/. The structure of P/sub 0/ has changed compared to typical lower energy data. The second peak is suppressed and a dip has appeared at mod t mod =3.6 (GeV/c)/sup 2/. (31 refs).

  20. Day-to-day consistency of lower extremity kinematics during stair ambulation in 24-45 years old athletes.

    Science.gov (United States)

    Husa-Russell, Johanna; Ukelo, Thomas; List, Renate; Lorenzetti, Silvio; Wolf, Peter

    2011-04-01

    Before making interpretations on the effects of interventions or on the features of pathological gait patterns during stair ambulation, the day-to-day consistency of the investigated variables must be established. In this article, the day-to-day consistency was determined for kinematic variables during barefoot stair ambulation. Ten healthy athletes performed two gait analysis sessions, at least one week apart, utilizing a marker set of 47 skin markers, and a functional joint center/axes determination. Being found on limits of agreement and mean differences between the repeated stair ambulation sessions, totally 43 ranges of motions were examined at the hip, knee, ankle, and midfoot joints. The day-to-day consistency was generally in the magnitude of three degrees, irrespective of test condition, investigated joint, or regarded cardinal body plane. The reported values of the day-to-day consistency provide guidelines to distinguish between pathological and healthy gait patterns, and thresholds to determine minimal effects of interventions during stair ambulation. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. Pseudorapidity distribution of shower particles in 24Mg-emulsion collisions at 4.5 A GeV/c

    International Nuclear Information System (INIS)

    Meng Cairong; Li Xiaolin; Duan Maiying

    2004-01-01

    The pseudorapidity distribution of shower particles produced in the 24 Mg-emulsion collisions at 4.5 A GeV/c is reported in this paper. The dependences of the distribution width and the peak position on the target size are observed. The pseudorapidity distribution of shower particles for the events with low target multiplicity (light target) is narrower than that with high target multiplicity (heavy target). The maximum probability pseudorapidity for light target is greater than that for heavy target. The experimental data is analyzed by using the cylinder model suggested by Liu et al. The Monte Carlo results based on Liu's cylinder model are approximately in agreement with the experimental tendency and fluctuation. (author)

  2. Outcomes in 24 selected patients with stage IVB cervical cancer and excellent performance status treated with radiotherapy and chemotherapy

    International Nuclear Information System (INIS)

    Zighelboim, Israel; Taylor, Nicholas P.; Powell, Matthew A.; Gibb, Randall K.; Rader, Janet S.; Mutch, David G.; Grigsby, Perry W.

    2006-01-01

    We sought to review outcomes in patients with stage IVB carcinoma of the cervix treated with irradiation in combination with chemotherapy. We report outcomes of 24 consecutive patients with good performance status treated from 1998 to 2005. Most of these patients underwent concurrent irradiation with platinum-based chemotherapy. Some patients received subsequent systemic chemotherapy. All patients underwent external beam radiotherapy; 7 patients (29%) had additional high-dose-rate and 12 (50%) low-dose-rate brachytherapy. Two patients (8%) received an intensity modulated radiation therapy (IMRT) boost instead of brachytherapy. The mean dose to point A was variable (73.9±19.2 Gy). Twenty patients (83%) received radio-sensitizing platinum-based chemotherapy, and the remaining had radiotherapy alone. Seven patients (29%) had further combination chemotherapy. Therapy was well tolerated. The overall survival was 44% at 36 months and 22% at 5 years. Patients with stage IVB cervical cancer have mostly been treated with palliative intent. With the advent of concurrent chemoradiation, we have treated many of these cases with aggressive combination therapy. In this series, the use of radiotherapy and multiagent chemotherapy in patients with stage IVB cervical carcinoma and good performance status was well tolerated and resulted in higher survival rates than previously reported. (author)

  3. Nursing assistants' behavior during morning care: effects of the implementation of snoezelen, integrated in 24-hours dementia care.

    NARCIS (Netherlands)

    Weert, J.C.M. van; Janssen, B.M.; Dulmen, A.M. van; Spreeuwenberg, P.M.M.; Bensing, J.M.; Ribbe, M.W.

    2006-01-01

    Aim: This paper reports an investigation of the effects of the implementation of snoezelen, or multisensory stimulation, on the quality of nursing assistants' behaviour during morning care. Background: Nursing assistants in long-term dementia care are often unaware of the impact of their behaviour

  4. Variable day/night bias in 24-h non-invasive finger pressure against intrabrachial artery pressure is removed by waveform filtering and level correction

    NARCIS (Netherlands)

    Westerhof, Berend E.; Guelen, Ilja; Parati, Gianfranco; Groppelli, Antonella; van Montfrans, Gert A.; Wieling, Wouter; Wesseling, Karel H.; Bos, Willem Jan W.

    2002-01-01

    Background Twenty-four-hour finger arterial pressure (FAP) recordings show a negative bias against intrabrachial artery pressure (BAP) and the bias is greater during the night thereby overestimating the nocturnal blood pressure dip. We have available a methodology with which to reconstruct BAP from

  5. Time bound changes (in 24 h in human sperm motility and level of calcium and magnesium in seminal plasma

    Directory of Open Access Journals (Sweden)

    J. Valsa

    2016-09-01

    Level of calcium (27.2 mg/dl and magnesium (13.54 mg/dl in seminal plasma did not show any significant changes during study period from that of at ½ h. The study concluded that electrolytes under study were not responsible for the decrease in motility during study period.

  6. Age-dependent changes in 24-hour rhythms of catecholamine content and turnover in hypothalamus, corpus striatum and pituitary gland of rats injected with Freund's adjuvant

    Directory of Open Access Journals (Sweden)

    Reyes Toso Carlos A

    2001-11-01

    Full Text Available Abstract Background Little information is available on the circadian sequela of an immune challenge in the brain of aged rats. To assess them, we studied 24-hour rhythms in hypothalamic and striatal norepinephrine (NE content, hypothalamic and striatal dopamine (DA turnover and hypophysial NE and DA content, in young (2 months and aged (18–20 months rats killed at 6 different time intervals, on day 18th after Freund's adjuvant or adjuvant's vehicle administration. Results Aging decreased anterior and medial hypothalamic NE content, medial and posterior hypothalamic DA turnover, and striatal NE concentration and DA turnover. Aging also decreased NE and DA content in pituitary neurointermediate lobe and augmented DA content in the anterior pituitary lobe. Immunization by Freund's adjuvant injection caused: (i reduction of DA turnover in anterior hypothalamus and corpus striatum; (ii acrophase delay of medial hypothalamic DA turnover in old rats, and of striatal NE content in young rats; (iii abolition of 24-h rhythm in NE and DA content of neurointermediate pituitary lobe, and in DA content of anterior lobe, of old rats. Conclusions The decline in catecholamine neurotransmission with aging could contribute to the decrease of gonadotropin and increase of prolactin release reported in similar groups of rats. Some circadian responses to immunization, e.g. suppression of 24-h rhythms of neurointermediate lobe NE and DA and of anterior lobe DA were seen only in aged rats.

  7. Circadian profiling reveals higher histamine plasma levels and lower diamine oxidase serum activities in 24% of patients with suspected histamine intolerance compared to food allergy and controls.

    Science.gov (United States)

    Pinzer, T C; Tietz, E; Waldmann, E; Schink, M; Neurath, M F; Zopf, Y

    2018-04-01

    Histamine intolerance is thought to trigger manifold clinical symptoms after ingesting histamine-rich food due to reduced activity of diamine oxidase (DAO). No study has hitherto systematically assessed daily fluctuations of histamine levels and DAO activities in symptomatic patients. The aim of the study was to investigate the presence of histamine intolerance, to therefore establish day profiles of histamine levels and DAO activities, and to compare the results between patients with suspected histamine intolerance, food allergy and healthy controls. We determined day profiles of histamine plasma levels and DAO serum activities in 33 patients with suspected histamine intolerance, in 21 patients with proven food allergy and in 10 healthy control patients. Clinical symptoms, food intolerances and further clinical and laboratory chemical parameters were evaluated. Twenty-four percent (8 of 33) suspected histamine-intolerant patients showed elevated histamine levels during the day. That might be caused by constantly and significantly reduced DAO activities in these patients compared to food-allergic and control patients. The remaining 25 patients presented normal histamine levels and DAO activities, but an increased prevalence of multiple food intolerances compared to the other subgroup of suspected histamine-intolerants. There was no correlation between subjective complaints and serological histamine parameters in patients with suspected histamine intolerance. We determined by daily profiling that decreased DAO activities correlated with elevated histamine levels in a subgroup of suspected histamine-intolerants. This finding discriminates these patients from food intolerant individuals with similar clinical symptoms and strongly suggests the presence of histamine intolerance. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  8. Risk-benefit evaluation of fish from Chinese markets: Nutrients and contaminants in 24 fish species from five big cities and related assessment for human health

    Energy Technology Data Exchange (ETDEWEB)

    Du, Zhen-Yu, E-mail: zdu@nifes.no [National Institute of Nutrition and Seafood Research (NIFES), N-5817 Bergen (Norway); Zhang, Jian [National Institute of Nutrition and Seafood Research (NIFES), N-5817 Bergen (Norway); Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, 100050 (China); Department of Biomedicine, University of Bergen (Norway); Wang, Chunrong; Li, Lixiang; Man, Qingqing [Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing, 100050 (China); Lundebye, Anne-Katrine; Froyland, Livar [National Institute of Nutrition and Seafood Research (NIFES), N-5817 Bergen (Norway)

    2012-02-01

    The risks and benefits of fish from markets in Chinese cities have not previously been fully evaluated. In the present study, 24 common fish species with more than 400 individual samples were collected from markets from five big Chinese cities in 2007. The main nutrients and contaminants were measured and the risk-benefit was evaluated based on recommended nutrient intakes and risk level criteria set by relevant authorities. The comprehensive effects of nutrients and contaminants in marine oily fish were also evaluated using the data of two related human dietary intervention trials performed in dyslipidemic Chinese men and women in 2008 and 2010, respectively. The results showed that concentrations of contaminants analyzed including DDT, PCB{sub 7}, arsenic and cadmium were much lower than their corresponding maximum limits with the exception of the mercury concentration in common carp. Concentrations of POPs and n-3 LCPUFA, mainly EPA and DHA, were positively associated with the lipid content of the fish. With a daily intake of 80-100 g marine oily fish, the persistent organic pollutants in fish would not counteract the beneficial effects of n-3 LCPUFA in reducing cardiovascular disease (CVD) risk markers. Marine oily fish provided more effective protection against CVD than lean fish, particularly for the dyslipidemic populations. The risk-benefit assessment based on the present daily aquatic product intake in Chinese urban residents (44.9 and 62.3 g for the average values for all cities and big cities, respectively) indicated that fish, particularly marine oily fish, can be regularly consumed to achieve optimal nutritional benefits from n-3 LCPUFA, without causing significant contaminant-related health risks. However, the potential health threat from contaminants in fish should still be emphasized for the populations consuming large quantities of fish, particularly wild fish. - Highlights: Black-Right-Pointing-Pointer We collected 24 fish species with more than 400 individual samples from five big Chinese cities. Black-Right-Pointing-Pointer The health risk-benefit was evaluated based on the nutrients and contaminants content in fish. Black-Right-Pointing-Pointer Two human trials were performed to evaluate the effects of contaminated fish on CVD prevalence. Black-Right-Pointing-Pointer Contaminants in these fish couldn't alleviate the benefits of fish n-3 LCPUFA in CVD prevention. Black-Right-Pointing-Pointer These fish in China can be regularly consumed without causing contaminant-related health risks.

  9. Measurement of the spin-forbidden decay rate (3s3d)1D2¿(3s3p)3 P2,1 in 24Mg

    DEFF Research Database (Denmark)

    Therkildsen, K. T.; Jensen, Brian Bak; Ryder, C. P.

    2009-01-01

    We have measured the spin-forbidden decay rate from (3s3d)D12¿(3s3p)P32,1 in M24g atoms trapped in a magneto-optical trap. The total decay rate, summing up both exit channels (3s3p)P31 and (3s3p)P32 , yields 196±10s-1 in excellent agreement with resent relativistic many-body calculations of Porse...

  10. Assessing the Universal Structure of Personality in Early Adolescence: The NEO-PI-R and NEO-PI-3 in 24 Cultures

    Science.gov (United States)

    De Fruyt, Filip; De Bolle, Marleen; McCrae, Robert R.; Terracciano, Antonio; Costa, Paul T., Jr.

    2009-01-01

    The structure and psychometric characteristics of the NEO Personality Inventory-3 (NEO-PI-3), a more readable version of the Revised NEO Personality Inventory (NEO-PI-R), are examined and compared with NEO-PI-R characteristics using data from college student observer ratings of 5,109 adolescents aged 12 to 17 years from 24 cultures. Replacement…

  11. Validation of digital photographs, as a tool in 24-h recall, for the improvement of dietary assessment among rural populations in developing countries

    Science.gov (United States)

    2012-01-01

    Background Improvement of traditional methods for dietary assessment is necessary, especially in rural areas where it is more difficult to succeed with self-reporting methods. This study presents and validates a method for improving accuracy when measuring food and nutrient intake of individuals in rural areas. It is called the “Food photography 24-h recall method” (FP 24-hR) and is a modified 24-h recall with the addition of a digital food photography record and a photo atlas. Methods The study was carried out in a rural area in the tropical region of Bolivia; 45 women participated. Validation of the method was made by comparing it with a reference method, the Weighed Food Record (WFR). During the FP 24-hR, digital photographs were taken by the subjects of all food consumed during a day and a 24-h recall questionnaire was conducted by an interviewer. An estimate of the amount of food consumed was made using a photo atlas and the photographs taken by the subjects. For validation, comparison was made between the calculations, by both methods, of the levels of food, and nutrient, intake. Results The comparison was made in 10 food categories; most of which were somewhat underestimated from −2.3% (cassava) to −6.8% (rice), except for beverages (+1.6%) and leafy vegetables (+8.7%), which were overestimated. Spearman’s correlation coefficients were highly significant (r from 0.75 for eggs to 0.98 for potato and cassava). Nutrient intakes calculated with data from both methods showed small differences from -0.90% (vitamin C) to -5.98% (fat). Although all nutrients were somewhat underestimated, Pearson′s coefficients are high (>0.93 for all) and statistically significant. Bland Altman analysis showed that differences between both methods were random and did not exhibit any systematic bias over levels of food and nutrient intake, with acceptable 95% limits of agreement. Conclusion The FP 24-hR exhibits acceptable differences when compared with a WFR, digital photos are useful as a memory aid for the subjects during 24-h recall and as an estimation tool. The method is suitable for assessing dietary intake among rural populations in developing countries. PMID:22931128

  12. Long-term outcome and MGMT as a predictive marker in 24 patients with atypical pituitary adenomas and pituitary carcinomas given treatment with temozolomide

    DEFF Research Database (Denmark)

    Bengtsson, Daniel; Schrøder, Henrik Daa; Andersen, Marianne

    2015-01-01

    , GH 4, GH/PRL 2). Ki-67 was 2-50% in LAPTs, and 5-80% in carcinomas. MAIN OUTCOME: Response to TMZ and the association with tumor expression of O6-methylguanine DNA methyltransferase (MGMT), MLH1, MSH2, and MSH6, examined by immunohistochemistry. RESULTS: Complete tumor regression occurred in two...

  13. A comprehensive study of fission in 24.3 MeV/nucleon U reactions induced on C, Si, Ni, Au targets

    International Nuclear Information System (INIS)

    Piasecki, E.; Pienkowski, L.; Czosnyka, T.; Iwanicki, J.; Muchorowska, M.; Tucholski, A.; Czarnacki, W.; Chbihi, A.; Galin, J.; Crema, E.; Sao Paulo Univ., SP

    1995-01-01

    Fission is a powerful tool for studying the primary reaction mechanisms in nucleus-nucleus collisions involving at least one fissionable nucleus. This is well shown when an additional information on the violence of the collision is provided by a totally independent observable such as the neutron multiplicity. The mass asymmetry in the entrance channel and the impact parameter are shown to have a decisive influence on the fate of the collision leading to either fusion or a two-body deeply inelastic reaction, analogous to what is known at lower bombarding energies. The experimental approach allows also to single out electromagnetic fission of U after interaction with Au and to provide some characteristics of such a process. (author)

  14. The influence of prosocial norms and online network structure on prosocial behavior : An analysis of Movember’s twitter campaign in 24 countries

    OpenAIRE

    Broek, T.A. van den; Need, A.; Ehrenhard, M.L.; Hiemstra, D.; Priante, A.

    2015-01-01

    Sociological research points at norms and social networks as antecedents of prosocial behavior. To date, the literature remains undecided on how these factors jointly influence prosocial behavior. Furthermore, the use of social media by campaign organizations may change the need for formal networks to organize large-scale collective action. Hence, in this paper we examine the interplay of prosocial norms and the structure of online social networks on offline prosocial behavior. For this purpo...

  15. Reconstrucción mamaria con expansor tisular e implante: Indicaciones y experiencia en 24 casos Breast reconstruction with tissue expander: Indications and experience in 24 cases

    Directory of Open Access Journals (Sweden)

    C. Gutiérrez Gómez

    2012-12-01

    Full Text Available En la actualidad, la reconstrucción mamaria forma parte integral del tratamiento del cáncer de mama; la selección de la paciente es crítica para obtener resultados satisfactorios. El presente trabajo recoge nuestra experiencia en reconstrucción mamaria con expansión tisular e implantes, haciendo hincapié en la selección de las pacientes candidatas a este método reconstructivo. Revisamos las reconstrucciones mamarias realizadas en un período comprendido entre los años 1998 y 2008 por la misma cirujana, analizando factores como tipo de mastectomía, edad, tiempo de la reconstrucción (inmediata o diferida, causa de la mastectomía, tipo de expansor y prótesis utilizados, complicaciones y satisfacción de las pacientes. En todas excepto en una, la reconstrucción se realizó en dos tiempos operatorios; durante el primero se hizo la colocación del expansor tisular y en el segundo, el cambio por la prótesis mamaria definitiva. Se realizaron un total de 24 reconstrucciones mamarias en 19 pacientes en el período de 10 años revisado, 14 unilaterales y 5 bilaterales. Las complicaciones presentadas en este grupo de pacientes fueron del 16,6 %. El seguimiento de las pacientes fue de 2 a 10 años. Solamente en 1 caso de cuadrantectomía, se realizó la reconstrucción de forma diferida por antecedente de radioterapia (4,1 %. En nuestra opinión, la reconstrucción mamaria con expansor tisular e implante es un procedimiento seguro, reproducible y con bajo índice de complicaciones, sin el inconveniente añadido de ocasionar morbilidad en el a área donante.Nowadays, breast reconstruction is part of breast carcinoma treatment; patient's selection plays an important role in satisfactory results. The present paper reports our experience in breast reconstruction with tissue expander/implant and emphasizes the importance of choosing the candidates for this method of reconstruction. We review the breast reconstructions realized in a 10 year period (1998-2008 by the same surgeon. We analyzed factors like type of mastectomy, age, time of the reconstruction (immediate or delayed, etiology, tissue expander and implant used complications and patients´ satisfaction. All the patients except one underwent breast reconstruction in two stages, first submuscular tissue expander, and second reconstruction replacement of tissue expander with implant. A total of 24 breast were reconstructed in 19 patients using tissue expander/implant in a 10 years period, 14 unilateral and 5 bilateral. In terms of complications, they were present n 16,6 % cases. The follow up period was between 2 and 10 years. There was only 1 patient with previous quadrantectomy who received radiotherapy (4,1 %. In our opinion, breast reconstruction with tissue expander/implant remains a safe and reliable method with minimal complications and without morbidity at the donor site.

  16. Risk–benefit evaluation of fish from Chinese markets: Nutrients and contaminants in 24 fish species from five big cities and related assessment for human health

    International Nuclear Information System (INIS)

    Du, Zhen-Yu; Zhang, Jian; Wang, Chunrong; Li, Lixiang; Man, Qingqing; Lundebye, Anne-Katrine; Frøyland, Livar

    2012-01-01

    The risks and benefits of fish from markets in Chinese cities have not previously been fully evaluated. In the present study, 24 common fish species with more than 400 individual samples were collected from markets from five big Chinese cities in 2007. The main nutrients and contaminants were measured and the risk–benefit was evaluated based on recommended nutrient intakes and risk level criteria set by relevant authorities. The comprehensive effects of nutrients and contaminants in marine oily fish were also evaluated using the data of two related human dietary intervention trials performed in dyslipidemic Chinese men and women in 2008 and 2010, respectively. The results showed that concentrations of contaminants analyzed including DDT, PCB 7 , arsenic and cadmium were much lower than their corresponding maximum limits with the exception of the mercury concentration in common carp. Concentrations of POPs and n-3 LCPUFA, mainly EPA and DHA, were positively associated with the lipid content of the fish. With a daily intake of 80–100 g marine oily fish, the persistent organic pollutants in fish would not counteract the beneficial effects of n-3 LCPUFA in reducing cardiovascular disease (CVD) risk markers. Marine oily fish provided more effective protection against CVD than lean fish, particularly for the dyslipidemic populations. The risk–benefit assessment based on the present daily aquatic product intake in Chinese urban residents (44.9 and 62.3 g for the average values for all cities and big cities, respectively) indicated that fish, particularly marine oily fish, can be regularly consumed to achieve optimal nutritional benefits from n-3 LCPUFA, without causing significant contaminant-related health risks. However, the potential health threat from contaminants in fish should still be emphasized for the populations consuming large quantities of fish, particularly wild fish. - Highlights: ► We collected 24 fish species with more than 400 individual samples from five big Chinese cities. ► The health risk–benefit was evaluated based on the nutrients and contaminants content in fish. ► Two human trials were performed to evaluate the effects of contaminated fish on CVD prevalence. ► Contaminants in these fish couldn't alleviate the benefits of fish n-3 LCPUFA in CVD prevention. ► These fish in China can be regularly consumed without causing contaminant-related health risks.

  17. The Influence of Prosocial Norms and Online Network Structure on Prosocial Behavior : An Analysis of Movember’s Twitter Campaign in 24 Countries

    NARCIS (Netherlands)

    van den Broek, Tijs Adriaan; Need, Ariana; Ehrenhard, Michel Léon; Priante, Anna; Hiemstra, Djoerd

    2015-01-01

    Sociological research points at norms and social networks as antecedents of prosocial behavior. To date, the literature remains undecided on how these factors jointly influence prosocial behavior. Furthermore, the use of social media by campaign organizations may change the need for formal networks

  18. Energy and nitrogen balances in 24 severely burned patients receiving 4 isocaloric diets of about 10 MJ/m2/day (2392 Kcalories/m2/day).

    Science.gov (United States)

    Serog, P; Baigts, F; Apfelbaum, M; Guilbaud, J; Chauvin, B; Pecqueur, M L

    1983-07-01

    Twenty-four subjects with burns ranging from 25-70 per cent received for 12 days exclusively per os a series of 4 isocaloric diets of about 4000 Kcal--'normal', or hyperproteic, or hyperlipidic, or hyperglucidic according to a randomized schedule. Oxygen consumptions were measured at the end of each diet and nitrogen balance was determined every day. Though patients were not massively overfed there remained a positive energy gap. The nitrogen balance was found to be equilibrated on the whole but clearly positive with the hyperproteic diet and clearly negative with the hyperlipidic-normoproteic diet. Thus there is no rationale for the huge energy overfeeding classically used.

  19. Predictors of placebo group decline in the Alzheimer's disease Assessment Scale-cognitive subscale (ADAS-Cog) in 24 week clinical trials of Alzheimer's disease.

    Science.gov (United States)

    Irizarry, Michael C; Webb, David J; Bains, Chanchal; Barrett, Steven J; Lai, Robert Y; Laroche, Janette P; Hosford, David; Maher-Edwards, Gareth; Weil, John G

    2008-07-01

    One limitation of several recent 24 week Alzheimer's disease (AD) clinical trials was the lack of cognitive decline detected by the AD Assessment Scale-cognitive subscale (ADAS-cog) in the placebo groups, possibly obscuring true medication effects. Data from 733 individuals in the placebo arms of six AD clinical trials performed 1996-1997 were pooled to examine the relationship of clinical, demographic, and genetic characteristics with the 24 week change in ADAS-cog. Baseline cognitive and functional status and the screening-to-baseline change in ADAS-cog were the strongest independent predictors of the 24 week change in ADAS-cog. The ADAS-cog did not detect progression in patients with mild dementia (screening Mini-Mental State Exam, MMSE, >or=20). The change in ADAS-cog from screening to baseline was inversely correlated with the 24 week change score; it was more difficult to detect cognitive decline at 24 weeks if individuals markedly worsened from screening to baseline. The effects of baseline MMSE and screening-to-baseline change in ADAS-cog generalized to the placebo group (N=106) of another AD study performed in 2004-2005. Overcoming lack of placebo decline in AD clinical trials will require scales more sensitive to cognitive decline in mild AD and strategies to reduce within-person variability in outcome measures.

  20. Assessing the Universal Structure of Personality in Early Adolescence: The NEO-PI-R and NEO-PI-3 in 24 cultures

    Czech Academy of Sciences Publication Activity Database

    De Fruyt, F.; De Bolle, M.; Aguilar-Vafaie, M.E.; Ahn, Ch.; Ahn, H.; Alcalay, L.; Allik, J.; Avdeyeva, T.V.; Blatný, Marek; Bratko, D.; Brunner-Sciarra, M.; Cain, T.R.; Chittcharat, N.; Crawford, J.T.; Fehr, R.; Ficková, E.; Gelfand, M.J.; Gulgoz, S.; Hřebíčková, Martina; Jussim, L.; Klinkosz, W.; Knežević, G.; Leibovich de Figueroa, N.; Lima, M.P.; Löckenhoff, C.E.; Martin, T.A.; Marušić, I.; Mastor, K.A.; Nakazato, K.; Nansubuga, F.; Porrata, J.; Purić, D.; Realo, A.; Reátegui, N.; Rolland, J.-P.; Schmidt, V.; Sekowski, A.; Shakespeare-Finch, J.; Shimonaka, Y.; Simonetti, F.; Siuta, J.; Szmigielska, B.; Vanno, V.; Wang, L.; Yik, M.

    2009-01-01

    Roč. 16, č. 3 (2009), s. 301-311 ISSN 1073-1911 R&D Projects: GA ČR GA406/07/1561 Institutional research plan: CEZ:AV0Z70250504 Keywords : adolescence * Five-Factor Model * cross - cultural * personality * observer ratings Subject RIV: AN - Psychology Impact factor: 1.974, year: 2009

  1. Determination of reference intervals and comparison of venous blood gas parameters using standard and non-standard collection methods in 24 cats.

    Science.gov (United States)

    Bachmann, Karin; Kutter, Annette Pn; Schefer, Rahel Jud; Marly-Voquer, Charlotte; Sigrist, Nadja

    2017-08-01

    Objectives The aim of this study was to determine in-house reference intervals (RIs) for venous blood analysis with the RAPIDPoint 500 blood gas analyser using blood gas syringes (BGSs) and to determine whether immediate analysis of venous blood collected into lithium heparin (LH) tubes can replace anaerobic blood sampling into BGSs. Methods Venous blood was collected from 24 healthy cats and directly transferred into a BGS and an LH tube. The BGS was immediately analysed on the RAPIDPoint 500 followed by the LH tube. The BGSs and LH tubes were compared using paired t-test or Wilcoxon matched-pairs signed-rank test, Bland-Altman and Passing-Bablok analysis. To assess clinical relevance, bias or percentage bias between BGSs and LH tubes was compared with the allowable total error (TEa) recommended for the respective parameter. Results Based on the values obtained from the BGSs, RIs were calculated for the evaluated parameters, including blood gases, electrolytes, glucose and lactate. Values derived from LH tubes showed no significant difference for standard bicarbonate, whole blood base excess, haematocrit, total haemoglobin, sodium, potassium, chloride, glucose and lactate, while pH, partial pressure of carbon dioxide and oxygen, actual bicarbonate, extracellular base excess, ionised calcium and anion gap were significantly different to the samples collected in BGSs ( P glucose and lactate can be made based on blood collected in LH tubes and analysed within 5 mins. For pH, partial pressure of carbon dioxide and oxygen, extracellular base excess, anion gap and ionised calcium the clinically relevant alterations have to be considered if analysed in LH tubes.

  2. Efecto de colutorio-gel de clorhexidina sobre el crecimiento de placa en 24 horas = Effect of chlorhexidine mouthrinses-gel on de novo plaque formation in 24 hours

    Directory of Open Access Journals (Sweden)

    Rivera, Tânia

    2006-01-01

    Full Text Available En un estudio cruzado, doble ciego y randomizado, 25 alumnos de Odontologia de buena salud oral, participaron de cuatro estudios donde ellos se abtuvieron de toda limpieza mecanica oral por 24 horas, los estudios estuvieron separados entre si por 4 semanas. Durante los estudios los alumnos en un randomizado orden, se enjuagaron por una vez con uno de los siguientes colutorios: CHX 0.12% + alcohol (Oralgene®, CHX 0.12% + alcohol (Perio.Aid®, CHX 0.1% + alcohol (Dentilim® y CHX 0.1% + HMC 2.5% (Colutoriogel®, nueva formula. Despues de un dia se midio formación de placa, se completo y registro el cuestionario de parametros clinicos. Las formulaciones de CHX 0.12% + alcohol y CHX 0.1% + HMC 2.5% se mostraron eficientes en retardar el crecimiento de placa dental de novo, esto obtenido de las observaciones clinicas, y siempre superior (p < 0.05 a la formulación del colutorio de CHX 0.1%+ alcohol (Dentilim®. Los resultados de este estudio demuestran el potencial clinico de este nuevo colutorio-gel sin alcohol de CHX 0.1% + HMC 2.5% (Colutoriogel® como un efectivo agente antiplaca y con reducidas efectos secundarios registrados

  3. Administration and Management of Irrigation Water in 24 User Organizations in Chile Administración y Gestión del Agua de Riego en 24 Organizaciones de Usuarios en Chile

    Directory of Open Access Journals (Sweden)

    Jara Jorge

    2009-06-01

    Full Text Available Approximately 85% of the water consumed in Chile is destined to agricultural irrigation and is managed by the users themselves. This study analyzed the price that irrigation water users pay to their Water User Associations (WUAs to which they belong and the relationship of this price to the professional level and performance of the WUAs. The study included 24 WUAs: 10 River Administration Boards (JV and 14 Irrigation Canal Associations (AC. The annual operational budget of each WUA, the price paid by users and the management capacities of the board of directors of each WUA were compared. The study also determined the relative value of user payments to WUAs as a proportion of total production costs of the main crops in each zone. The variability of user fees per irrigated hectare decreases when the irrigation area of the WUA is more than 10 000 ha, though this was not observed in JVs. The presence of technical-professional staff directly affects the development and growth of the WUAs. As well, the WUAs with a greater level of capacity development (NDC have more board members with a higher education level and have lower rates of unpaid user fees. The price that users pay to the WUA by irrigated hectare represents less than 4.0% of the average total production cost of the main crops in the study area. Finally, no correlation was found between the prices that users pay and the average profitability of the main crops, or between price and the geographical location of the WUAs.Aproximadamente, el 85% del agua consumida en Chile es destinada al riego agrícola, siendo administrada por los propios usuarios. En este estudio, se analizó el costo que cancelan los usuarios del agua de riego a sus Organizaciones de Usuarios de Agua (WUAs y el nivel de profesionalización y desempeño de éstas. Se estudiaron 24 WUAs: 10 Juntas de Vigilancia (JV y 14 Asociaciones de Canalistas (AC. Se comparó el presupuesto anual de operaciones de cada WUA, el valor que cancelan los usuarios y las capacidades de gestión de la directiva con el desempeño de la respectiva WUA. Además, se analizó la significancia del pago de los usuarios en los costos de producción de los principales cultivos en cada zona. En las AC, la variabilidad de precios por hectárea regada que cancelan los usuarios, disminuye cuando el territorio de la WUA es mayor a 10 000 ha, situación no detectada en las JV. El personal técnico-profesional de apoyo incide directamente sobre el desarrollo y crecimiento de las WUAs. Asimismo, las WUAs con nivel de desarrollo de capacidades (NDC más elevado poseen directivas con mayor escolaridad promedio y los usuarios presentan menor morosidad en el pago. El precio que cancelan los usuarios a las WUAs por hectárea regada representa menos del 4,0% de los costos promedio totales de producción de los principales cultivos de cada zona. Finalmente, no se evidenció correlación entre el precio que cancelan los usuarios y la rentabilidad promedio de los cultivos, ni por ubicación geográfica de las WUAs.

  4. Effects of Diclofenac, L-NAME, L-Arginine, and Pentadecapeptide BPC 157 on Gastrointestinal, Liver, and Brain Lesions, Failed Anastomosis, and Intestinal Adaptation Deterioration in 24 Hour-Short-Bowel Rats.

    Science.gov (United States)

    Lojo, Nermin; Rasic, Zarko; Zenko Sever, Anita; Kolenc, Danijela; Vukusic, Darko; Drmic, Domagoj; Zoricic, Ivan; Sever, Marko; Seiwerth, Sven; Sikiric, Predrag

    2016-01-01

    Stable gastric pentadecapeptide BPC 157 was previously used to ameliorate wound healing following major surgery and counteract diclofenac toxicity. To resolve the increasing early risks following major massive small bowel resectioning surgery, diclofenac combined with nitric oxide (NO) system blockade was used, suggesting therapy with BPC 157 and the nitric oxide synthase (NOS substrate) L-arginine, is efficacious. Immediately after anastomosis creation, short-bowel rats were untreated or administered intraperitoneal diclofenac (12 mg/kg), BPC 157 (10 μg/kg or 10 ng/kg), L-NG-nitroarginine methyl ester (L-NAME, 5 mg/kg), L-arginine (100 mg/kg) alone or combined, and assessed 24 h later. Short-bowel rats exhibited poor anastomosis healing, failed intestine adaptation, and gastrointestinal, liver, and brain lesions, which worsened with diclofenac. This was gradually ameliorated by immediate therapy with BPC 157 and L-arginine. Contrastingly, NOS-blocker L-NAME induced further aggravation and lesions gradually worsened. Specifically, rats with surgery alone exhibited mild stomach/duodenum lesions, considerable liver lesions, and severe cerebral/hippocampal lesions while those also administered diclofenac showed widespread severe lesions in the gastrointestinal tract, liver, cerebellar nuclear/Purkinje cells, and cerebrum/hippocampus. Rats subjected to surgery, diclofenac, and L-NAME exhibited the mentioned lesions, worsening anastomosis, and macro/microscopical necrosis. Thus, rats subjected to surgery alone showed evidence of deterioration. Furtheremore, rats subjected to surgery and administered diclofenac showed worse symptoms, than the rats subjected to surgery alone did. Rats subjected to surgery combined with diclofenac and L-NAME showed the worst deterioration. Rats subjected to surgery exhibited habitual adaptation of the remaining small intestine, which was markedly reversed in rats subjected to surgery and diclofenac, and those with surgery, diclofenac, and L-NAME. BPC 157 completely ameliorated symptoms in massive intestinal resection-, massive intestinal resection plus diclofenac-, and massive intestinal resection plus diclofenac plus L-NAME-treated short bowel rats that presented with cyclooxygenase (COX)-NO-system inhibition. L-arginine ameliorated only L-NAME-induced aggravation of symptoms in rats subjected to massive intestinal resection and administered diclofenac plus L-NAME.

  5. Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium Synechocystis sp. PCC 6803

    Directory of Open Access Journals (Sweden)

    Pistorius Elfriede K

    2007-11-01

    Full Text Available Abstract Background So far very limited knowledge exists on L-arginine catabolism in cyanobacteria, although six major L-arginine-degrading pathways have been described for prokaryotes. Thus, we have performed a bioinformatic analysis of possible L-arginine-degrading pathways in cyanobacteria. Further, we chose Synechocystis sp. PCC 6803 for a more detailed bioinformatic analysis and for validation of the bioinformatic predictions on L-arginine catabolism with a transcript analysis. Results We have evaluated 24 cyanobacterial genomes of freshwater or marine strains for the presence of putative L-arginine-degrading enzymes. We identified an L-arginine decarboxylase pathway in all 24 strains. In addition, cyanobacteria have one or two further pathways representing either an arginase pathway or L-arginine deiminase pathway or an L-arginine oxidase/dehydrogenase pathway. An L-arginine amidinotransferase pathway as a major L-arginine-degrading pathway is not likely but can not be entirely excluded. A rather unusual finding was that the cyanobacterial L-arginine deiminases are substantially larger than the enzymes in non-photosynthetic bacteria and that they are membrane-bound. A more detailed bioinformatic analysis of Synechocystis sp. PCC 6803 revealed that three different L-arginine-degrading pathways may in principle be functional in this cyanobacterium. These are (i an L-arginine decarboxylase pathway, (ii an L-arginine deiminase pathway, and (iii an L-arginine oxidase/dehydrogenase pathway. A transcript analysis of cells grown either with nitrate or L-arginine as sole N-source and with an illumination of 50 μmol photons m-2 s-1 showed that the transcripts for the first enzyme(s of all three pathways were present, but that the transcript levels for the L-arginine deiminase and the L-arginine oxidase/dehydrogenase were substantially higher than that of the three isoenzymes of L-arginine decarboxylase. Conclusion The evaluation of 24 cyanobacterial genomes revealed that five different L-arginine-degrading pathways are present in the investigated cyanobacterial species. In Synechocystis sp. PCC 6803 an L-arginine deiminase pathway and an L-arginine oxidase/dehydrogenase pathway represent the major pathways, while the L-arginine decarboxylase pathway most likely only functions in polyamine biosynthesis. The transcripts encoding the enzymes of the two major pathways were constitutively expressed with the exception of the transcript for the carbamate kinase, which was substantially up-regulated in cells grown with L-arginine.

  6. Space charge sign inversion and electric field reconstruction in 24 GeV/c proton-irradiated MCZ Si p+-n(TD)-n+ detectors processed via thermal donor introduction

    International Nuclear Information System (INIS)

    Li, Z.; Verbitskaya, E.; Carini, G.; Chen, W.; Eremin, V.; Gul, R.; Haerkoenen, J.; Li, M.

    2009-01-01

    The aim of this study is the evaluation of radiation effects in detectors based on p-type magnetic czochralski (MCZ) Si that was converted to n-type by thermal donor (TD) introduction. As-processed p + -p-n + detectors were annealed at 430 deg. C resulting in p + -n(TD)-n + structures. The space charge sign and the electric field distribution E(x) in MCz Si p + -n(TD)-n + detectors irradiated by 24 GeV/c protons were analyzed using the data on the current pulse response and the Double Peak (DP) electric field distribution model for heavily irradiated detectors. The approach considers an irradiated detector as a structure with three regions in which the electric field depends on the coordinate, and the induced current pulse response arises from the drift process of free carriers in the detector with variable electric field. Reconstruction of the E(x) profile from the pulse response shapes is performed employing a new method for DP electric field reconstruction. This method includes: (a) a direct extraction of charge loss due to trapping and (b) the fitting of a simulated pulse response to the 'corrected' pulse by adjusting the electric field profiles in the three regions. Reconstruction of E(x) distribution showed that in the diodes irradiated by a proton fluence of (2-4)x10 14 p/cm 2 space charge sign inversion has occurred. This is the evidence that the influence of 24 GeV/c proton radiation on MCz Si p + -n(TD)-n + detectors is similar to that on p + -n-n + detectors based on FZ or diffusion oxygenated n-type Si.

  7. This time it’s different? Effects of the Eurovision Debate on young citizens and its consequence for EU democracy–evidence from a quasi-experiment in 24 countries

    DEFF Research Database (Denmark)

    Maier, Jürgen; Faas, Thorsten; Rittberger, Berthold

    2018-01-01

    For the very first time in EU history, the 2014 EP elections provided citizens with the opportunity to influence the nomination of the Commission President by casting a vote for the main Europarties’ ‘lead candidates’. By subjecting the position of the Commission President to an open political...... contest, many experts have formulated the expectation that heightened political competition would strengthen the weak electoral connection between EU citizens and EU legislators, which some consider a root cause for the EU’s lack of public support. In particular, this contest was on display in the so...... citizens. Unfortunately, the debate has only reached a very small audience....

  8. Multi-sensory stimulation in 24-hour dementia care: effects of snoezelen on residents and caregivers = Zintuigactivering in de 24-uurszorg aan demente ouderen: effect van snoezelen op verpleeghuisbewoners en zorgverleners.

    NARCIS (Netherlands)

    Weert, J.C.M. van

    2004-01-01

    Demente verpleeghuisbewoners en hun verzorgers die met elkaar snoezelen tijdens de ochtendzorg (uit bed helpen, wassen, aankleden) lachen meer tegen elkaar. De bewoners worden met meer respect behandeld en mogen vaker zelf keuzes maken, ze zijn in een betere stemming, hebben meer plezier, zijn

  9. Actinides critical masses and the Paxton Woodcock rule

    International Nuclear Information System (INIS)

    Anno, Jacques; Duhamel, Isabelle; Lavarenne, Caroline; Duluc, Matthieu

    2003-01-01

    This paper presents recent actinides (reflected or not, moderated or not) critical masses calculations performed by the French standard route (APOLLO2 Sn 8 P3, 20 energy groups cross-section collapsed from 172 energy groups CEA 93 library). Comparisons are also presented against more accurate routes of the French criticality package CRISTAL, showing the fair conservatism of the standard values. Checks of the Paxton Woodcock rule for transportation exemption limit were also made. (author)

  10. Actinides critical masses and the Paxton Woodcock rule

    Energy Technology Data Exchange (ETDEWEB)

    Anno, Jacques; Duhamel, Isabelle; Lavarenne, Caroline [Institut de Radioprotection et de Surete Nucleaire, Fontenay aux Roses (France); Duluc, Matthieu [Institut National des Sciences et Techniques Nucleaires (INSTN) (France)

    2003-10-01

    This paper presents recent actinides (reflected or not, moderated or not) critical masses calculations performed by the French standard route (APOLLO2 Sn 8 P3, 20 energy groups cross-section collapsed from 172 energy groups CEA 93 library). Comparisons are also presented against more accurate routes of the French criticality package CRISTAL, showing the fair conservatism of the standard values. Checks of the Paxton Woodcock rule for transportation exemption limit were also made. (author)

  11. Contributions of each isotope in structural material on radiation damage in a hybrid reactor

    International Nuclear Information System (INIS)

    Günay, Mehtap

    2016-01-01

    In this study, the fluids were used in the liquid first-wall, blanket and shield zones of the designed hybrid reactor system. In this study, salt-heavy metal mixtures consisting of 93–85% Li_2_0Sn_8_0 + 5% SFG-PuO_2 and 2-10% UO_2, 93–85% Li_2_0Sn_8_0 + 5% SFG-PuO_2 and 2-10% NpO_2, and 93–85% Li_2_0Sn_8_0 + 5% SFG-PuO_2 and 2-10% UCO were used as fluids. In this study, the effect on the radiation damage of spent fuel-grade (SFG)-PuO_2, UO_2, NpO_2 and UCO contents was investigated in the structural material of a designed fusion–fission hybrid reactor system. In the designed hybrid reactor system were investigated the effect on the radiation damage of the selected fluid according to each isotopes of structural material in the structural material for 30 full power years (FPYs). Three-dimensional analyses were performed using the most recent MCNPX-2.7.0 Monte Carlo radiation transport code and the ENDF/B-VII.0 nuclear data library

  12. Protocolo de actuación preventiva para riesgo debido a alteraciones del ritmo circadiano en médicos de urgencias que trabajan en turnos de 24 horas Preventive action protocol for risk due to circadian rhythm disturbances in emergency physicians working in 24 hours shifts

    Directory of Open Access Journals (Sweden)

    Loreto Fillat de Acosta

    2009-12-01

    Full Text Available La autora analiza la situación patológica de los médicos de urgencias con turnos de 24 horas que alteran el ritmo circadiano, el estudio describe las condiciones de trabajo que afectan el ritmo biológico sueño-vigilia y las tareas intelectuales y de habilidades mecánicas desempeñadas por este personal, los daños a prevenir (accidentes in itinere, accidentes por manipulación de material biológico, enfermedades somáticas y psíquicas y el riesgo para los pacientes. Se propone un protocolo de actuación preventiva que abarca la mayor parte del trabajo, cuándo actuar, revisión de recursos, actuaciones a realizar en una unidad de salud laboral y sistema de comunicación al resto del hospital, Servicio de Prevención de Riesgos Laborales y Sistema Nacional de Salud.The author analyzes the pathological situation concerning to emergency physicians with 24-hour shifts which disturb their circadian rhythms, the study describes the working conditions that affect the biological sleep-wake rhythm and intellectual tasks and mechanical skills performed by these staff, damage to be prevented (commuting accidents, accidents caused by handling of biological material, somatic and psychic diseases and the risk to patients. After that, it's developed a proposal of preventive action protocol covering most of the work and finally when to act, available resources and actions to be taken in an occupational health unit, in addition to the communication system to the rest of the hospital, Occupational and Hazard Preventive Service and the National Health System.

  13. Hepatitis C: sexual or intrafamilial transmission? Epidemiological and phylogenetic analysis of hepatitis C virus in 24 infected couples Hepatite C: transmissão sexual ou intrafamiliar? Análise epidemiológica e filogenética do vírus da hepatite C em 24 casais infectados

    Directory of Open Access Journals (Sweden)

    Norma de Paula Cavalheiro

    2009-06-01

    Full Text Available The role of sexual or intrafamilial transmission of hepatitis C is controversial. A phylogenetic analysis was performed on the non-structural region 5B of the hepatitis C virus (NS5B-HCV. High percentages of homology (mean of 98.3% were shown between the couples. Twenty (83.3% of the 24 men but only two of the women (8.3% reported having had sexually transmitted diseases during their lives. The risk factors for HCV acquisition were blood transfusion (10 couples, use of illegal injected drugs (17, use of inhalants (15, acupuncture (5 and tattoos (5. The shared use of personal hygiene items included toothbrushes between six couples (25%, razor blades between 16 (66.7%, nail clippers between 21 (87.5% and manicure pliers between 14 (58.3%. The high degree of similarity of the hepatitis C virus genome supports the hypothesis of hepatitis C virus transmission between these couples. The shared use of personal hygiene items suggests the possibility of intrafamilial transmission of infection.O papel da transmissão sexual ou intrafamiliar da hepatite C é controverso. Foi feita análise filogenética, região não estrutural 5B do vírus da hepatite C (NS5B-HCV. Altas percentagens de homologia com média de 98,3% foi revelada entre os casais. Vinte (83,3% de 24 homens, contra apenas duas (8,3% mulheres reportaram doença sexualmente transmisível durante suas vidas. Os fatores de risco para aquisição da doença foram: transfusão de sangue para 10 casais, uso de drogas ilícitas injetáveis para 17, inalatórias para 15, acupuntura em 5 e tatuagens para 5. O compartilhamento de utensílios de higiene pessoal incluem: escova de dente para seis (25% dos casais, lâmina de barbear para 16 (66,7%, cortador de unhas para 21 (87,5% e alicate de manicure para 14 (58,3%. O alto grau de similaridade genômica entre os vírus da hepatite C suporta a hipótese de transmissão entre os casais. O uso compartilhado de utensílios de higiene pessoal sugere a possibilidade de transmissão intrafamiliar.

  14. TOTAL CHOLESTEROL, HIGH DENSITY LIPOPROTEINS (HDL AND CORTISOL PLASMA LEVELS, AND THEIR BIORHYTMICITY, IN 24 HOURS, THROUGHOUT YEAR, IN IDEAL-POLWARTH RAMS NÍVEIS PLASMÁTICOS DE COLESTEROL TOTAL, LIPOPROTEÍNAS DE ALTA DENSIDADE (HDL E CORTISOL, E SUA BIORRITMICIDADE, EM CARNEIROS IDEAL-POLWARTH

    Directory of Open Access Journals (Sweden)

    Alcides de Amorim Ramos

    2006-12-01

    Full Text Available To evaluate the mean plasma concentrations of total cholesterol (TC, high density lipoproteins (HDL and cortisol, blood samples were collected of five Ideal-Polwarth rams, maintained at 22?53’S latitude, in semi-confinement, every two months throughout the year, by 24h period, with 2-hour intervals between colects. The TC, changed 40.70?1,11mg/dL (April and 61.48?1,11mg/dL (December, between months, while HDL changed 22.16?0.23mg/dL (December as 33.40?0.23mg/dL (February, but not make evident a circannual rhythm in this levels. The TC presented the lowest value at 16:30h (50.40?1.57mg/dL and the highest value at 8:30h collect (54.67?1.57mg/dL; the HDL lowest level was at 10:30h (27.04?0.33mg/dL and the highest level also at 8:30h collect (28.49?0.33mg/dL, however without permit circadian rhythm determination in your plasma concentrations. Similarly, the cortisol plasma concentrations, between collect months, presents variable, however without demonstrate circadian rhythm in this hormone secretion. In relation to different collection’s moments, throughout months, it wasn’t possible to define, by statistical analysis, a circadian rhythm of cortisol secretion. KEY WORDS: Ovine, adrenal hormone, biochemistry metabolites, circadian rhythm. Visando avaliar as concentrações médias de colesterol total (CT, lipoproteínas de alta densidade (HDL e cortisol plasmáticos, foram colhidas amostras de sangue de cinco carneiros Ideal-Polwarth, alocados em latitude 22°53’S, em regime de semiconfinamento, a cada dois meses, ao longo de um ano, com as colheitas em um período de 24 horas, e intervalos de duas horas entre elas. O CT oscilou entre 40,70±1,11mg/dL (abril e 61,48±1,11mg/dL (dezembro, entre os meses, enquanto HDL variou de 22,16±0,23mg/dL (dezembro a 33,40±0,23mg/dL (fevereiro, mas não evidenciando um ritmo circanual em seus níveis. O CT apresentou seu valor mínimo na colheita das 16h30min (50,40±1,57mg/dL e o máximo às 8h30min (54,67±1,57mg/dL; o menor valor de HDL foi obtido às 10h30min (27,04±0,33mg/dL e o mais alto também às 8h30min (28,49±0,33mg/dL, não permitindo a determinação de um ritmo circadiano em suas concentrações plasmáticas. De forma similar, as concentrações de cortisol plasmático, entre os meses de colheita, apresentaram-se variáveis, mas ainda sem demonstrar um ritmo circanual na secreção deste hormônio. Com relação aos diferentes momentos de colheita, ao longo das 24 horas, assim como entre os meses, não foi estatisticamente possível a definição de um ritmo circadiano de secreção de cortisol. PALAVRAS-CHAVE: Hormônio adrenal, metabólitos bioquímicos, ovinos, ritmo circadiano.

  15. Clinical characteristics and evolution of syphilis in 24 HIV+ individuals in Rio de Janeiro, Brazil Características clínicas e evolutivas da sífilis em 24 indivíduos HIV+ no Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Maria Clara Gutierrez-Galhardo

    2005-06-01

    Full Text Available A total of 24 patients with syphilis and HIV infection were treated from January 1997 to March 2003 at the Infectious Dermatology Outpatient Clinic of the Evandro Chagas Clinical Research Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. The caseload consisted of 20 males (83.3% and four females (16.7%, with a mean age of 38.04 years and mean T CD4+ count of 389.5 cells/mL. Syphilis was diagnosed as secondary in 16 (62.5% patients, late latent in eight (33.3%, and tertiary in one (4.2%. Manifestations of secondary syphilis were palmar and plantar erythematopapulous cutaneous lesions in nine (37.5%, papulous exanthema in four (16.7%, patchy alopecia in 3 (12.5% and osteochondritis in one patient (4.2%. Tertiary syphilis was characterized by verrucous lesions. Neurosyphilis was diagnosed in four patients (16.7%, with headache as the only manifestation in two patients. Drugs used in treatment included benzathine penicillin, ceftriaxone, erythromycin, and crystalline penicillin. Cure was achieved in 18 patients (75%. Five patients (20.8% were retreated, three of whom presented a history of re-exposure. This study confirms the importance of establishing the diagnosis of neurosyphilis in patients with HIV infection, in addition to performing follow-up on treatment for syphilis.Foram tratados 24 indivíduos com sífilis e infecção pelo HIV, de Março de 1997 a Janeiro de 2003, no ambulatório de Dermatologia Infecciosa do Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil. Foram 20 homens (83,3% e quatro mulheres (16,7% com idade média de 38,04 anos e contagem média de linfócitos T CD4 de 389,5 céls/mm³. A sífilis foi classificada como secundária em 16 pacientes (62,5%, latente tardia em oito (33,3% e terciária em uma paciente (4,2%. As manifestações de sífilis secundária foram de lesões cutâneas eritematopapulosas em regiões palmar e plantar em nove (37,5%, exantema papuloso em quatro (16,7%, alopecia em clareira em três (12,5% e osteocondrite em um paciente (4,2%. A sífilis terciária apresentou-se como lesão verrucosa. Cinco pacientes (20,8% apresentavam neurossífilis, sendo a cefaléia a única manifestação presente em dois pacientes. As drogas utilizadas foram penicilina benzatina, ceftriaxone, eritromicina e penicilina. A cura ocorreu em 18 pacientes (75%. Seis pacientes (25% foram retratados, sendo que três apresentavam história de re-exposição. Este estudo confirmou a importância de se estabelecer o diagnóstico de neurossífilis em pacientes com infecção pelo HIV, assim como de se realizar seguimento clínico e laboratorial após o tratamento da sífilis.

  16. Temperature dependence of the resistivity and tunneling magnetoresistance of sputtered FeHf(Si)O cermet films

    NARCIS (Netherlands)

    Strijkers, G.J.; Swagten, H.J.M.; Rulkens, B.; Bitter, R.H.J.N.; Jonge, de W.J.M.; Bloemen, P.J.H.; Schep, K.M.

    1998-01-01

    We have studied the tunneling resistivity and magnetoresistance of reactive sputter deposited FeHfO and FeHfSiO thin granular films. Maximum magnetoresistance ratios at room temperature of 2% and 3.2% were observed for films with compositions of Fe47Hf10O43 and Fe40Hf6Si6O48, respectively. The

  17. Cu-Nb3Sn superconducting wires prepared by ''Copper Liquid Phase Sintering method'' using the Nb-H

    International Nuclear Information System (INIS)

    Resende, A.T. de.

    1985-01-01

    Cu-30% Nb in weighting were prepared by the method of Copper sintering liquid phase the method was improved by substitution of Nb power by Nb-H powder, obtaining a high density material with good mechanical properties, which was reduced to fine. Wire, Without heat treatment. The Cu-Nb 3 Sn wires were obtained by external diffusion process depositing tin in the Cu-30%Nb wires, and by internal diffusion process using the Sn-8.5% Cu in weighting, which was reduced to rods of 3.5 mm. These Cu-30%Nb rods were enclosed in copper tubes and deformed mechanically by rotary swaging and drawing. During the drawing step some wires were fractured, that were analysed and correlated with the microstructure of the Sn-8.5 Wt% Cu alloy. External and internal diffusion samples; after a fast thermal treatment for Sn diffusion, were submited to the temperature of 700 0 C to provide the reaction between Sn and Nb, leading to the Nb 3 Sn phase. Samples with several reaction times, and its influence on T c and J c critical parameters and normal resistivity were prepared and analysed. (author) [pt

  18. Short-wavelength out-of-band EUV emission from Sn laser-produced plasma

    Science.gov (United States)

    Torretti, F.; Schupp, R.; Kurilovich, D.; Bayerle, A.; Scheers, J.; Ubachs, W.; Hoekstra, R.; Versolato, O. O.

    2018-02-01

    We present the results of spectroscopic measurements in the extreme ultraviolet regime (7-17 nm) of molten tin microdroplets illuminated by a high-intensity 3 J, 60 ns Nd:YAG laser pulse. The strong 13.5 nm emission from this laser-produced plasma (LPP) is of relevance for next-generation nanolithography machines. Here, we focus on the shorter wavelength features between 7 and 12 nm which have so far remained poorly investigated despite their diagnostic relevance. Using flexible atomic code calculations and local thermodynamic equilibrium arguments, we show that the line features in this region of the spectrum can be explained by transitions from high-lying configurations within the Sn{}8+-Sn{}15+ ions. The dominant transitions for all ions but Sn{}8+ are found to be electric-dipole transitions towards the n = 4 ground state from the core-excited configuration in which a 4p electron is promoted to the 5s subshell. Our results resolve some long-standing spectroscopic issues and provide reliable charge state identification for Sn LPP, which could be employed as a useful tool for diagnostic purposes.

  19. Effect of nano Ni additions on the structure and properties of Sn-9Zn and Sn-Zn-3Bi solders in Au/Ni/Cu ball grid array packages

    Energy Technology Data Exchange (ETDEWEB)

    Gain, Asit Kumar [Department of Electronic Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong); Chan, Y.C. [Department of Electronic Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong)], E-mail: eeycchan@cityu.edu.hk; Yung, Winco K.C. [Department of Industrial and Systems Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon (Hong Kong)

    2009-05-25

    The effect of nano Ni additions in Sn-9Zn and Sn-8Zn-3Bi solders on their interfacial microstructures and shear loads with Au/Ni/Cu pad metallization in ball grid array (BGA) applications were investigated. After the addition of nano Ni powder in Sn-based lead-free solders, there were no significant changes in the interfacial microstructure. But, in the solder region a very fine Zn-rich phase was observed. Also on the fracture surfaces a fine Zn-Ni compound was found. After the addition of nano Ni powder in Sn-based solders, the shear loads were increased due to a refinement of the microstructure and in addition, ductile fracture surfaces were clearly observed. The shear loads of the plain Sn-9Zn and Sn-8Zn-3Bi solders after one reflow cycle were about 1798 g and 2059 g, respectively. After the addition of nano Ni powder, their loads were about 2172 g and 2212 g, respectively, after one reflow cycle and their shear loads after eight reflow cycles were about 2099 g and 2081 g, respectively.

  20. Effect of nano Ni additions on the structure and properties of Sn-9Zn and Sn-Zn-3Bi solders in Au/Ni/Cu ball grid array packages

    International Nuclear Information System (INIS)

    Gain, Asit Kumar; Chan, Y.C.; Yung, Winco K.C.

    2009-01-01

    The effect of nano Ni additions in Sn-9Zn and Sn-8Zn-3Bi solders on their interfacial microstructures and shear loads with Au/Ni/Cu pad metallization in ball grid array (BGA) applications were investigated. After the addition of nano Ni powder in Sn-based lead-free solders, there were no significant changes in the interfacial microstructure. But, in the solder region a very fine Zn-rich phase was observed. Also on the fracture surfaces a fine Zn-Ni compound was found. After the addition of nano Ni powder in Sn-based solders, the shear loads were increased due to a refinement of the microstructure and in addition, ductile fracture surfaces were clearly observed. The shear loads of the plain Sn-9Zn and Sn-8Zn-3Bi solders after one reflow cycle were about 1798 g and 2059 g, respectively. After the addition of nano Ni powder, their loads were about 2172 g and 2212 g, respectively, after one reflow cycle and their shear loads after eight reflow cycles were about 2099 g and 2081 g, respectively.

  1. Contribuição ao conhecimento da ictiofauna do Manguezal de Cacha Pregos, Ilha de Itaparica, Baía de Todos os Santos, Bahia Contribution to knowledge of ichthyofauna of Mangrove Cacha Pregos, Itaparica island, Todos os Santos bay, Bahia

    Directory of Open Access Journals (Sweden)

    Paulo Roberto Duarte Lopes

    1998-01-01

    Full Text Available A check-list of fishes collected in a mangrove in Cacha Pregos, south of ltaparic Island, State of Bahia, Brazil (about 13o07'S,38o48'W from 1988-1989 and 1991-1992 is presented. Fifteen orders, 46 families and 85 species (Teleostei except one Chondrichthyes were identified, represented specimens whose adults live in different marine ecossystems.

  2. Microcavity single virus detection and sizing with molecular sensitivity

    Science.gov (United States)

    Dantham, V. R.; Holler, S.; Kolchenko, V.; Wan, Z.; Arnold, S.

    2013-02-01

    We report the label-free detection and sizing of the smallest individual RNA virus, MS2 by a spherical microcavity. Mass of this virus is ~6 ag and produces a theoretical resonance shift ~0.25 fm upon adsorbing an individual virus at the equator of the bare microcavity, which is well below the r.m.s background noise of 2 fm. However, detection was accomplished with ease (S/N = 8, Q = 4x105) using a single dipole stimulated plasmonic-nanoshell as a microcavity wavelength shift enhancer. Analytical expressions based on the "reactive sensing principle" are developed to extract the radius of the virus from the measured signals. Estimated limit of detection for these experiments was ~0.4 ag or 240 kDa below the size of all known viruses, largest globular and elongated proteins [Phosphofructokinase (345 kDa) and Fibrinogen (390 kDa), respectively].

  3. Why archeological tourism does not work?: Evidence from two discoveries in Kosovo

    OpenAIRE

    Mulaj, Isa

    2014-01-01

    This paper brings the evidence about two unique archeological discoveries in Kosovo: i) Fingerprints in a rock from Pleistocene period; and ii) the Star of David, the Flower of Life, the Tree of Life, and “Eye of the Masonry” found together engraved in a marble stone 1 meter long and 30 centimeters wide. The carbon test (C14) of the latter puts the age of the engravings circa 2 500 BCE. It was found by the Author in 2013, located in the coordinate 42o48’41.50”N 20o34’16.00” E, 400 metres away...

  4. Dicty_cDB: VHO576 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available mal sarcosine oxidase; S... 48 1e-04 BC114006_1( BC114006 |pid:none) Bos taurus L-pipecolic acid oxidas... 4...8 1e-04 BC088249_1( BC088249 |pid:none) Rattus norvegicus pipecolic acid o... 48 2e-04 AY892312_1( AY892312 ...id:none) Pongo abelii mRNA; cDNA DKFZp469L1... 48 2e-04 BC027622_1( BC027622 |pid:none) Homo sapiens pipecoli

  5. Pulsed laser deposition of epitaxial Sr(RuxSn1-x)O3 thin film electrodes and KNbO3/Sr(RuxSn1-x)O3 bilayers

    International Nuclear Information System (INIS)

    Christen, H.M.; Boatner, L.A.; English, L.Q.; Geea, L.A.; Marrero, P.J.; Norton, D.P.

    1995-01-01

    Sr(Ru x Sn 1-x ) 3 is proposed as a new conducting oxide for use in epitaxial multilayer structures. The Sr(Ru o 48 Sn 0.52 )0 3 composition exhibits an excellent lattice match with (100)-oriented KTaO 3 , and films of this composition grown by pulsed laser deposition on KTaO 3 , SrTiO 3 , and LaAlO 3 substrates have been analyzed by X-ray diffraction, Rutherford backscattering/ion channeling, and resistivity measurements. Epitaxial KNbO 3 /Sr(Ru 0.48 Sn 0.52 )O 3 bilayers have been successfully grown

  6. [Reptile-associated salmonellosis as an important epidemiological problem].

    Science.gov (United States)

    Pawlak, Aleksandra

    2014-11-17

    of food poisoning. One of the reservoirs of Salmonella are reptiles, which are increasingly kept as pets. Most reptiles are asymptomatic carriers of Salmonella. These strains, isolated from reptiles, can cause serious infections, especially in infants, young children and people with immunodeficiencies. The disease called reptile-associated salmonellosis (RAS) may manifest with bloody diarrhea, meningitis, and arthritis, and consequently can cause bacteremia and sepsis. Among the strains described in the literature, Salmonella strains possessing the O48 antigen are an important group. Lipopolysaccharide (LPS) of Salmonella O48 contains sialic acid (NeuAc) in an O-specific-chain. LPS containing NeuAc exhibits antigenic similarity to antigens found in the human body, including blood serum, and therefore is correlated with the occurrence of the dangerous phenomenon of molecular mimicry. Bacteria containing NeuAc in their outer structures can evade the immunological response of the host, which significantly increases their virulence. Most data about RAS come from the USA, but in recent years cases from European countries are more frequent in the literature. Unfortunately, the occurrence of RAS in Poland has not been monitored so far. There is also no campaign to inform the public about the health risks connected with contact of people with reptiles.

  7. Diffusion couple studies of the Ni-Bi-Sn system

    Directory of Open Access Journals (Sweden)

    Vassilev G.

    2012-01-01

    Full Text Available Investigations of Ni-Bi-Sn system were performed in order to inquire the phase diagram and to assess some diffusion kinetic parameters. For this purpose diffusion couples consisting of solid nickel (preliminary electroplated with tin and liquid Bi-Sn phase were annealed at 370 °C. Three compositions (0.8, 0.6 and 0.4 mole fractions Sn of the Bi-Sn melts were chosen. Annealing times from 24 to 216 h were applied. The phase and chemical compositions of the contact zone were determined by means of electron scanning microscope. It was confirmed that the diffusion layers consist mainly of Ni3Sn4 but other intermetallic phases grow as well. For the first time metastable Ni-Sn phases as NiSn and NiSn8 (NiSn9 were observed in metallurgical alloys (i.e. not in electroplated samples. The existence of a ternary compound previously reported in the literature was confirmed. More than one ternary Ni-Bi-Sn compounds might possibly be admitted. A growth coefficient of (2.29 ± 0.02 x 10-15 m2 s-1 was obtained. It was found that the apparent activation energy for diffusion layers growth (18 ± 8 kJ mol-1 is inferior to that one assessed at growth from solid state Bi-Sn mixtures (88 ± 12 kJ mol-1.

  8. United States Air Force Statistical Digest, Fiscal Year 1962, Seventeenth Edition

    Science.gov (United States)

    1962-09-30

    1,377 77 162 505 1,062 9 128 2. l53 1.090 hQ2Q12 298 531 249 2,459 ~50 1.587 302 75831 65 113201 ~ ,,2~3 ~ 12 392 580 279 2,6o~; 48 ~ 300 75885 75132222 92...2 6 MIUTARY AIR TRANSPORT SERVICE - TOTAL. .’ 942,269 13 1 g td 13 ! I 1 25 ~1st Quarter 223,571 3" I - - - - 2 I Ŗnd Quarter 232,692 2 1...Air Ccmnand 9 1 - - B 259 39,270 USAF Academy td 1 - - - 1 4 120 ill Air Forces in Europe. 45 1 - - 44 649 50,970 USAFSecurity Service, 5 - - - 5 214

  9. Diseño y desarrollo del hardware de un hólter para pacientes con Parkinson

    OpenAIRE

    Amor Morales, Joan del

    2015-01-01

    El hólter es un dispositivo médico que registra determinados datos (generalmente de origen biométrico) del paciente que lo lleva. Actualmente, el hólter más extendido es el que registra los ritmos cardíacos del paciente. El paciente lleva el hólter durante 24h o 48h haciendo vida normal y, al pasar este período de tiempo, para que los profesionales clínicos puedan tener un registro de la evolución temporal de la actividad eléctrica cardiaca y detectar comportamientos o situaciones patológicas...

  10. Magicity of neutron-rich nuclei within relativistic self-consistent approaches

    Directory of Open Access Journals (Sweden)

    Jia Jie Li

    2016-02-01

    Full Text Available The formation of new shell gaps in intermediate mass neutron-rich nuclei is investigated within the relativistic Hartree–Fock–Bogoliubov theory, and the role of the Lorentz pseudo-vector and tensor interactions is analyzed. Based on the Foldy–Wouthuysen transformation, we discuss in detail the role played by the different terms of the Lorentz pseudo-vector and tensor interactions in the appearing of the N=16, 32 and 34 shell gaps. The nuclei 24O, 48Si and 52,54Ca are predicted with a large shell gap and zero (24O, 52Ca or almost zero (48Si, 54Ca pairing gap, making them candidates for new magic numbers in exotic nuclei. We find from our analysis that the Lorentz pseudo-vector and tensor interactions induce very specific evolutions of single-particle energies, which could clearly sign their presence and reveal the need for relativistic approaches with exchange interactions.

  11. Dicty_cDB: Contig-U15683-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ame: Full=Ubiquitin carboxyl-terminal hydrolase 4; ... 41 0.14 BC143354_1( BC143354 |pid:none) Homo sapiens ...pe... 41 0.14 ( Q92353 ) RecName: Full=Ubiquitin carboxyl-terminal hydrolase 6; ... 41 0.14 AC140026_8( AC140026 |pid:none) Med...e-07 1 ( AC116979 ) Dictyostelium discoideum chromosome 2 map 6445720... 54 1e-06 2 ( ER292388 ) 1092343612868 Global-Ocean-Sampli...ing embryo clone:m... 50 4e-05 2 ( EJ238241 ) 1095323012610 Global-Ocean-Sampling_GS-27-01-01-1... 40 3e-04 ...siae mRNA, clone: S03052-24_O... 48 0.35 2 ( EK189498 ) 1095460013501 Global-Ocean-Sampling_GS-31-01-01-1...

  12. Vitamin D Repletion Reduces the Progression of Premalignant Squamous Lesions in the NTCU Lung Squamous Cell Carcinoma Mouse Model

    Science.gov (United States)

    Mazzilli, Sarah A.; Hershberger, Pamela A.; Reid, Mary E.; Bogner, Paul N.; Atwood, Kristopher; Trump, Donald L.; Johnson, Candace S.

    2015-01-01

    The chemopreventive actions of vitamin D were examined in the N-nitroso-tris-chloroethylurea (NTCU) mouse model, a progressive model of lung squamous cell carcinoma (SCC). SWR/J mice were fed a deficient diet (D) containing no vitamin D3, a sufficient diet (S) containing 2000 IU/kg vitamin D3, or the same diets in combination with the active metabolite of vitamin D, calcitriol (C) (80 μg/kg, weekly). The percentage (%) of the mucosal surface of large airways occupied by dysplastic lesions was determined in mice after treatment with a total dose of 15 or 25 μmol NTCU (N). After treatment with 15 μmol NTCU, the % of the surface of large airways containing high-grade dysplastic (HGD) lesions were vitamin D-deficient +NTCU (DN), 22.7 % (p<0.05 compared to vitamin D-sufficient +NTCU (SN)); DN + C, 12.3%; SN, 8.7%; and SN + C, 6.6%. The extent of HGD increased with NTCU dose in the DN group. Proliferation, assessed by Ki-67 labeling, increased upon NTCU treatment. The highest Ki-67 labeling index was seen in the DN group. As compared to SN mice, DN mice exhibited a 3-fold increase (p <0.005) in circulating white blood cells (WBC), a 20% (p <0.05) increase in IL-6 levels, and a 4 -fold (p <0.005) increase in WBC in bronchial lavages. Thus, vitamin D repletion reduces the progression of premalignant lesions, proliferation, and inflammation, and may thereby suppress development of lung SCC. Further investigations of the chemopreventive effects of vitamin D in lung SCC are warranted. PMID:26276745

  13. César Augusto Restrepo Valencia, Consuelo Vélez Álvarez Abstract Objective. To evaluate the effectiveness of calcineurin ciclosporin and tacrolimus inhibitors to induce remission in patients with refractory lupus nephritis. Patients, materials and methods. Patients with lupus nephritis class IV-G who despite receiving therapy with high doses of steroid and with a cytostatic (cyclophosphamide or mycophenolate for 3 months had not been able to induce some kind of remission.The exclusion criteria were creatinine levels greater than 3 mg / dl, pregnancy, previous history of exposure to calcineurin inhibitors, cancer, active infections, uncontrolled hypertension, and negligence with medication intake. The recommended dose of cyclosporine was 3 mg / kg / day and tacrolimus 0.1 mg / kg / day, in joint with prednisone 0.3 mg / kg / day, cyclophosphamide 1 mg / kg / day or mycophenolate mofetil 1 gram every 12 hours. The cyclophosphamide was administered only during 6 months, after which it was changed to azathioprine at doses of 1 mg / kg / day. Still, mycophenolate was continued at the same dose. All patients completed a minimum period of 12 months follow-up, it was considered that patients achieved partial remission when proteinuria decreased by 50% of the baseline value or its value decreased to less than 1 gram in 24 hours, decrease of leukocytes count and red blood cells in urine of 50%, and creatinine values were stable. A complete remission was considered when there was a reduction in proteinuria in a value less than 300 mg per 24 hours, urinary sediment with less than 3 red blood cells, less than 5 leukocyte for each high power microscopic field, and a creatinine value reduction by 50% or reaching a normal value. Results. Twelve patients met the inclusion criteria and initiated the calcineurin inhibitor protocol. Two presented accelerated deterioration in their function and required chronic dialysis therapy. Ten patients with active treatment completed 12 months

    Directory of Open Access Journals (Sweden)

    César Augusto Restrepo Valencia

    2014-10-01

    Full Text Available Objective: To evaluate the effectiveness of calcineurin ciclosporin and tacrolimus inhibitors to induce remission in patients with refractory lupus nephritis. Patients, materials and methods: Patients with lupus nephritis class IV-G who despite receiving the rapy with high doses of steroid and with a cytostatic (cyclophosphamide or mycophenolate for 3 months had not been able to induce some kind of remission.The exclusion criteria were creatinine levels greater than 3 mg / dl, pregnancy, previous history of exposure to calcineurin inhibitors, cancer, active infections, uncontrolled hypertension, and negligence with medication intake. The recommended dose of cyclosporine was 3 mg / kg / day and tacrolimus 0.1 mg / kg / day, in joint with prednisone 0.3 mg / kg / day, cyclophosphamide 1 mg / kg / day or mycophenolate mofetil 1 gram every 12 hours. The cyclophosphamide was administered only during 6 months, after which it was changed to azathioprine at doses of 1 mg / kg / day. Still, mycophenolate was continued at the same dose. All patients completed a minimum period of 12 months follow-up, it was considered that patients achieved partial remission when proteinuria decreased by 50% of the baseline value or its value decreased to less than 1 gram in 24 hours, decrease of leukocytes count and red blood cells in urine of 50%, and creatinine values were stable. A complete remission was considered when there was a reduction in proteinuria in a value less than 300 mg per 24 hours, urinary sediment with less than 3 red blood cells, less than 5 leukocyte for each high power microscopic field, and a creatinine value reduction by 50% or reaching a normal value. Results: Twelve patients met the inclusion criteria and initiated the calcineurin inhibitor protocol. Two presented accelerated deterioration in their function and required chronic dialysis therapy. Ten patients with active treatment completed 12 months of followup, of which 4 (40% had partial

  14. Ferromagnetism in Gd doped ZnO nanowires: A first principles study

    KAUST Repository

    Aravindh, S. Assa

    2014-12-19

    In several experimental studies, room temperature ferromagnetism in Gd-doped ZnO nanostructures has been achieved. However, the mechanism and the origin of the ferromagnetism remain controversial. We investigate the structural, magnetic, and electronic properties of Zn 48O48 nanowires doped with Gd, using density functional theory. Our findings indicate that substitutionally incorporated Gd atoms prefer occupying the surface Zn sites. Moreover, the formation energy increases with the distance between Gd atoms, signifying that no Gd-Gd segregation occurs in the nanowires within the concentration limit of ≤2%. Gd induces ferromagnetism in ZnO nanowires with magnetic coupling energy up to 21 meV in the neutral state, which increases with additional electron and O vacancy, revealing the role of carriers in magnetic exchange. The potential for achieving room temperature ferromagnetism and high TC in ZnO:Gd nanowires is evident from the large ferromagnetic coupling energy (200 meV) obtained with the O vacancy. Density of states shows that Fermi level overlaps with Gd f states with the introduction of O vacancy, indicating the possibility of s-f coupling. These results will assist in understanding experimental findings in Gd-doped ZnO nanowires.

  15. ¿Cuál es el mejor método para estimar variables en yacimientos lateríticos de níquel y cobalto?

    Directory of Open Access Journals (Sweden)

    Niurka Pérez-Melo

    2006-03-01

    Full Text Available Para determinar el método más adecuado de estimar los contenidos de hierro, níquel y cobalto en los yacimientos lateríticos del nordeste de Cuba, se compararon los errores puntuales asociados a varios algoritmos de estimación y simulación, tomando como caso de estudio el bloque O48 del Yacimiento Punta Gorda. La comparación se basó en los resultados de la técnica de jackknife. Los métodos de estimación y simulación lognormal, krigeage con modelo de spline, simulación gaussiana secuencial y simulación condicional por el método de bandas rotantes, esta última con 100 bandas aleatorias. En todos los casos se alcanzaron resultados similares con respecto a la media de los errores, a excepción del krigeage con modelo de spline. La diferencia entre los métodos sólo se hace evidente al comparar las distribuciones de frecuencias de dichos errores. Se demuestra que la exactitud de la estimación, en este caso de estudio, está más influenciada por las características de los datos experimentales y de la estrategia (o elipsoide de búsqueda, que por los métodos de estimación que se empleen.

  16. From Stable ZnO and GaN Clusters to Novel Double Bubbles and Frameworks

    Directory of Open Access Journals (Sweden)

    Matthew R. Farrow

    2014-05-01

    Full Text Available A bottom up approach is employed in the design of novel materials: first, gas-phase “double bubble” clusters are constructed from high symmetry, Th, 24 and 96 atom, single bubbles of ZnO and GaN. These are used to construct bulk frameworks. Upon geometry optimization—minimisation of energies and forces computed using density functional theory—the symmetry of the double bubble clusters is reduced to either C1 or C2, and the average bond lengths for the outer bubbles are 1.9 Å, whereas the average bonds for the inner bubble are larger for ZnO than for GaN; 2.0 Å and 1.9 Å, respectively. A careful analysis of the bond distributions reveals that the inter-bubble bonds are bi-modal, and that there is a greater distortion for ZnO. Similar bond distributions are found for the corresponding frameworks. The distortion of the ZnO double bubble is found to be related to the increased flexibility of the outer bubble when composed of ZnO rather than GaN, which is reflected in their bulk moduli. The energetics suggest that (ZnO12@(GaN48 is more stable both in gas phase and bulk frameworks than (ZnO12@(ZnO48 and (GaN12@(GaN48. Formation enthalpies are similar to those found for carbon fullerenes.

  17. The preparation and characterization of Cu(II complexes with N,N’,N”,N’”-tetrakis(2-pyridylmethyl-1,4,8,11-tetraazacyclotetradecane and 2,6-diacetylpyridine bis(semi/thiosemicarbazones

    Directory of Open Access Journals (Sweden)

    GORDANA VUCKOVIC

    2004-03-01

    Full Text Available Two new Cu(II mixed-ligand complexes with octadentate N,N’,N”,N’”-tetrakis(2-pyridylmethyl-1,4,8,11-tetraazacyclotetradecane (tpmc and potentially pentadentate ligands 2,6-diacetylpyridine bis(semicarbazone (DAPsc2 or 2,6-diacetylpyridine bis(thiosemicarbazone (DAPtsc2 were prepared. The general formulas: [Cu4 DAPsc2(tpmc2]ClO48·5CH3COCH3·H2O and [Cu2 DAPtsc2(tpmc](ClO44·7C2H5OH were proposed on the basis of elemental analyses and conductometric measurements. The complexes were characterized by magnetic measurement, electronic absorption and IR spectroscopy. For the dinuclear complex, an exo coordination of Cu(II with four nitrogens from tpmc and m-bonded DAPtsc2 through sulfurs and possibly terminal hydrazinic (azomethine nitrogens is assumed. For the tetranuclear complex, it is supposed that one DAPsc2 bridges two [Cu2 tpmc]4+ units using oxygens and terminal hydrazinic nitrogens as ligators. Finally, some antibacterial activity of the complexes was found.

  18. Sedimentación de pulpas minerales lateríticas en la tecnología de lixiviación ácida a presión: incidencia de la composición mineralógica

    Directory of Open Access Journals (Sweden)

    José Falcón-Hernández

    2007-03-01

    Full Text Available La tecnología de lixiviación ácida a presión que utiliza la industria hidrometalúrgica cubana para la producción de níquel no alcanza a la salida del tanque espesador la concentración de sólidos según lo establecido en el diseño (48 %, lo que repercute negativamente en la economía nacional. Mediante difracción de rayos-x (DRX se determinaron las fases mineralógicas existentes en la mena y con los ensayos de sedimentación se estudió el comportamiento de éstas en las pulpas lateríticas. Se concluye que la presencia de hematita, magnetita y maghemita (fases minerales de metales pesados favorece el proceso de sedimentación de la pulpa mientras que la presencia de fases de metales ligeros como la gibbsita, cuarzo, antigorita y hematita, producen el efecto contrario.

  19. Effects of harvest time on production and chemical evolution of Jerusalem artichoke (Helianthus tuberosus L.) cultivated in the Mediterranean area

    Energy Technology Data Exchange (ETDEWEB)

    Losavio, N.; Ventrella, D.; Lamascese, N.; Vonella, A.V. [Istituto Sperimentale Agronimico, Bari (Italy)

    1997-07-01

    The purpose of this paper is to determine the optimum harvest time and to evaluate biomass and sugar production of a Jerusalem artichoke crop. Field trials were conducted during 1994 and 1995 at Metaponto (MT) in southern Italy (lat. 40{sup o} 24'N; long. 16{sup o} 48' E) on clay loam soil (Typic Epiaquerts in accordance with soil taxonomy). In both years tubers were planted at the end of March with a density of 7.4 plants m{sup -2} (0.45 m rows spacing). The Jerusalem artichoke crop (cv. ''Violette de Rennes'') was irrigated during the whole growing cycle by re-establishment of 50% maximum evapotranspiration on the basis of agrometeorological data. Tubers and stalks were harvested at a plant height of 0.25 and 0.5 m; 40 and 20 days before flowering stage; at flowering stage; and at physiological maturity stage. Tubers and stalks were analyzed for fresh and dry matter weight, and for fructose and glucose contents determined by the Samogyi-Nelsen method. Our observations show that the best harvest times were at flowering stage (for stalk production) and at physiological maturity stage (for tuber production). (author)

  20. Aspectos eco-epidemiológicos da leishmaniose tegumentar americana no Município de Campinas

    Directory of Open Access Journals (Sweden)

    Corte Antônio Ângelo

    1996-01-01

    Full Text Available Os autores descrevem um surto de leishmaniose tegumentar americana ocorrido no período de fevereiro de 1993 a setembro de 1994, nos Distritos de Sousas e Joaquim Egídio, Município de Campinas, SP. Ocorreram 25 casos, sete na área rural, nove na área peri-urbana e nove na urbana. Verifica-se uma mobilidade da ocorrência dos casos em direção rural-urbana. Em relação ao sexo, houve predomínio do masculino (60% sobre o feminino (40%, com 44% dos casos concentrados na faixa etária de 11 e trinta anos. Quanto à ocupação, 48% correspondem a estudantes, empregadas domésticas e donas-de-casa. Em 92% dos casos, a doença manifestou-se com lesão única, predominantemente localizadas nos membros inferiores e superiores. O surgimento desses casos na área está provavelmente associado à expansão urbana ocorrida nas décadas de 70-80 e acelerada mais recentemente.

  1. Localized-itinerant magnetism: a simple model with applications to intermetallic of heavy rare-earths

    International Nuclear Information System (INIS)

    Ranke Perlingueiro, P.J. von.

    1986-01-01

    We have investigated various magnetic quantities of a system consisting of conduction electrons coupled to localized spins. In obtaining the magnetic state equations (which relate the ionic and electronic magnetisations to temperature and the model parameters) we have adopted the molecular field approximation. This simple model is of interest to the magnetism of the heavy rare earth intermettallics. For these systems the localized spin is that of the 4f shell; it is described by the parameters g (the Lande's factor) and J (the total angular momentum of the 4f electrons in the ground state). We derive an analytical linear relation between the critical temperature and The Gennes Factors J(J+1)(g-1) which is experimentally observed for RAl 2 . A fitting between the experimental points and the theoretical prediction gives for the exchange parameter the value J o = 48.6 meV. We have also performed a parametric study of the model, using a rectangular energy density of states. The results are shown on tables and diagrams. (author) [pt

  2. Energy evaluation of the Eucalyptus globulus and the Eucalyptus nitens in the north of Spain (Cantabria)

    International Nuclear Information System (INIS)

    Perez, S.; Renedo, C.J.; Ortiz, A.; Manana, M.; Silio, D.

    2006-01-01

    This work studied the potential use of the waste from Eucalyptus globulus and Eucalyptus nitens as energy crops, evaluating young and adult stages of both in all four seasons of the year with different moisture contents. The study was carried out made in Cantabria (North coast of Spain), located at latitude 43 o 28'N, and longitude 3 o 48'W. In this region, 29,513ha are dedicated to the growth of Eucalyptus, with about 80% E. globulus, and 20% E. nitens. Six different plantations have been analyzed and their bioclimatic diagrams determined. After the collection of samples the potential energy of every sample was obtained, they were weighed, analyzed and burned, giving a mean net calorific value of 17,384 and 17,927kJ/kg in the adult stage of E. globulus and E. nitens, respectively. The results for the young stage of both species were 17,708 and 18,670kJ/kg. Moisture content in the samples has a great influence on power production. Finally, the economic and environmental consequences of these crop species for the region of Cantabria were analyzed. (author)

  3. HIGH PERCENTAGE OF RARE EARTH ELEMENT CONNECTION WITH THE ACCUMULATION SEDIMENT AS RESPONSE LONGSHORE CURRENTS IN THE BELITUNG WATERS

    Directory of Open Access Journals (Sweden)

    Delyuzar Ilahude

    2017-07-01

    Full Text Available The study area is geographically located in the West coast of Belitung island at coordinates 105o48'00" - 106o06' 00" E and 06o46'00" - 06o50' 00" S. The beach and coastal area is influenced by wave energy from the West and North directions The purpose of this study is to analyze the relationship between the zone of sediment accumulation of empirical approaches on oceanography parameter containing rare earth elements. The approach used is to predict the shore wave energy using wave prediction curve deep waters to obtain the energy flux of the wave at each point of reference. Sediments containing rare earth elements tend to lead to the south as a result of the movement of longshore currents. Regional coastal area of the western part of the island of Belitung, especially in the southern part of the estuary of the river Tanjung Pandan is estimated to be a zone of sediment accumulation. The movement of sediment caused by wave energy from the north led to sedimentation evolved significantly in the south which is thought to contain rare earths minerals derived from land. This sedimentation process takes place on a seasonal basis, which allegedly took place in the west. The movement of sediment to the south of the mouth of the Cerucuk River it is predicted that rare earth elements were supplied from these rivers tend to settle in the southern part of the estuary Cerucuk throughout the year.

  4. Ferromagnetism in Gd doped ZnO nanowires: A first principles study

    KAUST Repository

    Aravindh, S. Assa; Schwingenschlö gl, Udo; Roqan, Iman S.

    2014-01-01

    In several experimental studies, room temperature ferromagnetism in Gd-doped ZnO nanostructures has been achieved. However, the mechanism and the origin of the ferromagnetism remain controversial. We investigate the structural, magnetic, and electronic properties of Zn 48O48 nanowires doped with Gd, using density functional theory. Our findings indicate that substitutionally incorporated Gd atoms prefer occupying the surface Zn sites. Moreover, the formation energy increases with the distance between Gd atoms, signifying that no Gd-Gd segregation occurs in the nanowires within the concentration limit of ≤2%. Gd induces ferromagnetism in ZnO nanowires with magnetic coupling energy up to 21 meV in the neutral state, which increases with additional electron and O vacancy, revealing the role of carriers in magnetic exchange. The potential for achieving room temperature ferromagnetism and high TC in ZnO:Gd nanowires is evident from the large ferromagnetic coupling energy (200 meV) obtained with the O vacancy. Density of states shows that Fermi level overlaps with Gd f states with the introduction of O vacancy, indicating the possibility of s-f coupling. These results will assist in understanding experimental findings in Gd-doped ZnO nanowires.

  5. Cloning, periplasmic expression, purification and structural characterization of human ribosomal protein L10

    International Nuclear Information System (INIS)

    Pereira, Larissa Miranda

    2009-01-01

    The ribosomal protein L10 (RP L10) is a strong candidate to be included in the class of tumor suppressor proteins. This protein, also denominated as QM, is known to participate in the binding of ribosomal subunits 60S and 40S and the translation of mRNAs. It has a molecular weight that varies between 24 and 26 kDa and an isoelectric point of (pI) 10.5. The sequence of the protein QM is highly conserved in mammals, plants, invertebrates, insects and yeast which indicates its critical functions in a cell. As a tumor suppressor, RP L10 has been studied in strains of Wilm's tumor (WT-1) and tumor cells in the stomach, where was observed a decrease in the amount of its mRNA. More recently, the RP L10 was found in low amounts in the early stages of prostate adenoma and showed some mutation in ovarian cancer, what indicates its role as a suppressor protein in the development of these diseases. It has also been described that this protein interacts with c-Jun and c-Yes inhibiting growth factors and consequently, cell division. This work has an important role on the establishment of soluble expression of QM to give base information for further studies on expression that aim to evaluate the specific regions where it acts binding the 60S and 40S ribosomal subunits and translation, as well as its binding to proto-oncogenes. The cDNA for QM protein was amplified by PCR and cloned into periplasmic expression vector p3SN8. The QM protein was expressed in E. coli BL21 (DE3) in the region of cytoplasm and periplasm, the best condition was obtained from the expression of the recombinant plasmid QM p1813 Q M at 25 degree C or 30 degree C, the soluble protein was obtained with small amounts of contaminants. The assays of secondary structure showed that the QM protein is predominantly alpha-helix, but when it loses the folding, this condition changes and the protein is replaced by β- sheet feature. (author)

  6. Cognitive performance patterns in healthy individuals with substantia nigra hyperechogenicity and early Parkinson’s disease

    Directory of Open Access Journals (Sweden)

    Rezzak Yilmaz

    2016-11-01

    Full Text Available Introduction: Hyperechogenicity of the substantia nigra (SN+ is a risk marker for Parkinson’s disease (PD which can be detected before the diagnosis. In healthy individuals, SN+ has been associated with slight deficits in specific cognitive functions, suggesting cognitive impairment as a possible pre-diagnostic marker for PD. However, the pattern of cognitive deficits associated with SN+ has not yet been compared with those present in PD.Methods: Data of 262 healthy individuals with normal echogenicity (SN- and 48 healthy individuals with SN+ were compared with 82 early stage PD patients using the Consortium to Establish a Registry for Alzheimer’s disease test battery. First, the test clusters (factors were identified using a principal component analysis (PCA. Mean group performance of cognitive tests belonging to distinct factors, according to the PCA, and single subtest performances were compared using analyses of variance. Second, the number of individuals with abnormal cognitive performances (z-score <-1.0 were compared between groups. Results: Verbal memory, semantic and executive function, and praxis were identified as components of cognitive performances. The SN+ group performed significantly worse than the SN- group in tests assessing semantic and executive function, with a non-significant decrease in verbal memory. On the subtest level, individuals of the SN+ group scored significantly lower than the SN- group on the Boston Naming Test (BNT (p=0.008. In all subtests, the percentages of PD patients with values below the cut-off for abnormal performance were higher than in the SN- group. Moreover, more individuals from the SN+ group scored below the cut-off in the BNT (SN-=8.4%, SN+=20.8%, p=0.01 and TMT-B (SN-=6.9%, SN+=16.7%, p=0.02, compared to the SN- group. Conclusion: This study confirms poorer performance of healthy individuals with SN+ compared to SN- in specific cognitive domains. However, against the SN- group, the cognitive

  7. Lifetime and g-factor of a new isomer in 130 La

    International Nuclear Information System (INIS)

    Ionescu-Bujor, M.; Iordachescu, A.; Brandolini, F.; Pavan, P.; Rossi Alvarez, C.; De Poli, M.; Medina, N.H.; Rao, M.N.

    1999-01-01

    Pulsed-beam measurements have been recently performed at the XTU-tandem of the National Laboratory of Legnaro with the aim to investigate short-lived isomeric states in neutron-deficient nuclei of the A∼130 region. Isotopically enriched tin targets were irradiated with a 70 MeV 16 O beam (pulse width of 3 ns at a repetition rate of 800 ns) and the γ-ray angular distributions perturbed in magnetic or electric interaction were observed time-differentially. Static electromagnetic moments were thus determined for several known short-lived isomers in 129,130,131 Ce and 129 Ba. In these experiments a new isomeric decay has been also identified and its properties are reported in the present work. The isomer has been observed on a target containing 116 Sn (87%), 117 Sn (8%) and 118 Sn (5%). The tin target of 0.6 mg/cm 2 thickness evaporated on a Pb foil was placed in an external magnetic field of 32 kG whose orientation was periodically reversed. Two planar HPGe detectors positioned at ±135 deg. with respect to the beam direction were used for the γ-ray detection. In the delayed spectra a γ-ray of 105.2 keV has been observed and a half-life of 32(5)ns has been determined for it. The experimental and calculated R(t) modulation ratios of the 105.2 keV γ-ray in the external magnetic field are given. From the derived Larmor frequency a value g = + 0.48(3) has been determined for the isomeric state g-factor. A dipole character has been established for the delayed 105.2 keV γ-transition based on the determined negative A 2 coefficient. The new isomer was tentatively assigned to the odd-odd 130 La populated in the 116,117,118 Sn ( 16 O,pxn) reaction. In this nucleus a state at (150.3 + x) keV de-excited by a 105.2 keV transition is known and it was identified with the isomer. Further experiments are in progress for the definite assignment and the elucidation of the isomer configuration. (authors)

  8. Alloy characterization of a 7th Century BC archeological bronze vase — Overcoming patina constraints using Monte Carlo simulations

    Energy Technology Data Exchange (ETDEWEB)

    Manso, M. [Laboratório de Instrumentação, Engenharia Biomédica e Fisica da Radiação (LIBPhys-UNL), Departamento de Fisica, Faculdade de Ciências e Tecnologias, Universidade Nova de Lisboa, 2829-516 Monte da Caparica (Portugal); Faculdade de Belas-Artes da Universidade de Lisboa, Largo da Academia Nacional de Belas-Artes, 1249-058 Lisboa (Portugal); Schiavon, N. [Hercules Laboratory, University of Évora, Palácio do Vimioso,Largo Marquês de Marialva 8, 7000-809 Évora Portugal (Portugal); Queralt, I. [Laboratory of X-ray Analytical Applications, Institute of Earth Sciences Jaume Almera, CSIC, Solé Sabaris s/n, 08028 Barcelona (Spain); Arruda, A.M. [Centro de Arqueologia da Universidade de Lisboa (UNIARQ), Alameda da Universidade, 1600-214 Lisboa (Portugal); Sampaio, J.M. [BioISI — Biosystems & Integrative Sciences Institute, Faculdade de Ciências da Universidade de Lisboa (Portugal); Brunetti, A., E-mail: brunetti@uniss.it [Department of Political Science and Communication, University of Sassari, Via Piandanna 2, 07100 Sassari (Italy)

    2015-05-01

    In this work we evaluate the composition of a bronze alloy using X-ray fluorescence spectrometry (XRF) and Monte Carlo (MC) simulations. For this purpose, a 7th Century BC archeological vase from the SW Iberian Peninsula, displaying a well formed corrosion patina was analyzed by means of a portable X-ray fluorescence spectrometer. Realistic MC simulations of the experimental setup were performed with the XRMC code package which is based on an intensive use of variance-reduction techniques and uses XRAYLIB a constantly updated X-ray library of atomic data. A single layer model was applied for simulating XRF of polished/pristine bronze whereas a two-or-three-layer model was developed for bronze covered respectively by a corrosion patina alone or coupled with a superficial soil derived crust. These simulations took into account corrosion (cerussite (PbCO{sub 3}), cuprite (Cu{sub 2}O), malachite (Cu{sub 2}CO{sub 3}(OH){sub 2}), litharge (PbO)) and soil derived products (goethite (FeO(OH)) and quartz (SiO{sub 2})) identified by means of X-ray diffraction and Raman micro analytical techniques. Results confirm previous research indicating that the XRF/Monte Carlo protocol is well suited when a two-layered model is considered, whereas in areas where the patina + soil derived products' crust is too thick, X-rays from the alloy substrate are not able to exit the sample. Quantitative results based on MC simulations indicate that the vase is made of a lead–bronze alloy: Mn (0.2%), Fe (1.0%), Cu (81.8%), As (0.5%), Ag (0.6%), Sn (8.0%) and Pb (8.0%). - Highlights: • We study an archeological bronze vase with patina corrosion using XRF spectrometry. • The experimental setup is modeled using Monte Carlo (MC) simulations. • Combining MC simulations with XRF it is possible to derive concentrations. • We demonstrated that this is possible without removing the patina.

  9. Cloning, periplasmic expression, purification and structural characterization of human ribosomal protein L10; Clonagem, expressao, purificacao e caracterizacao estrutural da proteina ribossomal L10 humana recombinante

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Larissa Miranda

    2009-07-01

    The ribosomal protein L10 (RP L10) is a strong candidate to be included in the class of tumor suppressor proteins. This protein, also denominated as QM, is known to participate in the binding of ribosomal subunits 60S and 40S and the translation of mRNAs. It has a molecular weight that varies between 24 and 26 kDa and an isoelectric point of (pI) 10.5. The sequence of the protein QM is highly conserved in mammals, plants, invertebrates, insects and yeast which indicates its critical functions in a cell. As a tumor suppressor, RP L10 has been studied in strains of Wilm's tumor (WT-1) and tumor cells in the stomach, where was observed a decrease in the amount of its mRNA. More recently, the RP L10 was found in low amounts in the early stages of prostate adenoma and showed some mutation in ovarian cancer, what indicates its role as a suppressor protein in the development of these diseases. It has also been described that this protein interacts with c-Jun and c-Yes inhibiting growth factors and consequently, cell division. This work has an important role on the establishment of soluble expression of QM to give base information for further studies on expression that aim to evaluate the specific regions where it acts binding the 60S and 40S ribosomal subunits and translation, as well as its binding to proto-oncogenes. The cDNA for QM protein was amplified by PCR and cloned into periplasmic expression vector p3SN8. The QM protein was expressed in E. coli BL21 (DE3) in the region of cytoplasm and periplasm, the best condition was obtained from the expression of the recombinant plasmid QM p1813{sub Q}M at 25 degree C or 30 degree C, the soluble protein was obtained with small amounts of contaminants. The assays of secondary structure showed that the QM protein is predominantly alpha-helix, but when it loses the folding, this condition changes and the protein is replaced by {beta}- sheet feature. (author)

  10. Rescuing Our Warriors from Chronic Pain: A Battlefield-to-Nondeployment Means to Prevent Opioid-induced Amplification of Neuropathic Pain from Traumatic Injury

    Science.gov (United States)

    2017-10-01

    meters ran in 24 hours. BL 1 2 3 4 5 6 7 8 9 10 11 12 2 3 4 0 200 400 600 800 % B L m et er s ra...following surgery. we ek 1 we ek 2 we ek 3 we ek 4 we ek 5 0 200 400 600 Percent of Baseline Meters Ran in 24 hours weekly post dosing...presented as percentage of baseline meters ran in 24 hours. (p>.05, Two way ANOVA, n=4/group pilot data) 10 Figure 6. No significant effects

  11. 24 CFR 4001.07 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... in 24 CFR 203.251(e). Premium pricing means the price for the sale of a mortgage loan with an above... for real estate taxes, premiums for required hazard and mortgage insurance, homeowners' association...

  12. Analgesic efficacy of low-dose intrathecal neostigmine in combination with fentanyl and bupivacaine for total knee replacement surgery

    Directory of Open Access Journals (Sweden)

    Amit Jain

    2012-01-01

    Conclusions: The addition of 1 mcg neostigmine IT increased the duration of analgesia and decreased the analgesic consumption in 24 h in TKR. There was no increase in the incidence of adverse effects.

  13. African Journal of Biotechnology - Vol 11, No 72 (2012)

    African Journals Online (AJOL)

    African Journal of Biotechnology. ... Microsatellite based investigation of genetic diversity in 24 synthetic wheat cultivars ... The influence of protective properties of packaging materials and application of modified atmosphere on packed dried ...

  14. The Electro-Encephalogram in Phenylketonuria

    Science.gov (United States)

    Todd, Peter G.; Pitt, D. B.

    1973-01-01

    Evaluated were electroencephalographic findings in 24 untreated (ages from 4 to 38 years) patients suffereing from phenylketonuria (a metabolic disorder producing severe mental retardation if not treated with proper diet during the early years). (DB)

  15. Electrocatalysis in fuel cells a non- and low- platinum approach

    CERN Document Server

    Shao, Minhua

    2014-01-01

    In 24 chapters written by worldwide experts, this book details the fundamentals and applications of novel electrocatalysts, and summarizes recent advances in oxygen reduction and alcohol oxidation, with a particular focus on non- and low-Pt electrocatalysts.

  16. 24 CFR 207.258 - Insurance claim requirements.

    Science.gov (United States)

    2010-04-01

    ... in 24 CFR part 200, subpart B, of its intention to file an insurance claim and of its election either..., ledger cards, documents, books, papers, and accounts relating to the mortgage transaction. (iv) All...

  17. The effect of S. pneumoniae bacteremia on cerebral blood flow autoregulation in rats

    DEFF Research Database (Denmark)

    Pedersen, Michael; Brandt, Christian T.; Knudsen, Gitte Moos

    2008-01-01

    during incremental reductions in cerebral perfusion pressure (CPP) by controlled hemorrhage. Autoregulation was preserved in all rats without meningitis (groups A and E) and was lost in 24 of 25 meningitis rats (groups B, C, and D) (P

  18. 24 CFR 884.102 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES... Market Rent (FMR), HUD, Public housing agency (PHA), and Secretary are defined in 24 CFR part 5...

  19. Recto-sigmoid polypectomy by a handmade snare: Experience of 24 children with bleeding per rectum

    Directory of Open Access Journals (Sweden)

    Manoj Saha

    2014-01-01

    Full Text Available A handmade snare is designed from easily available materials to treat bleeding per rectum in children due to rectosigmoid polyps. A total of 29 polypectomies were done in 24 patients. It is simple, effective, safe and economic.

  20. Concentrations of prioritized pharmaceuticals in effluents from 50 large wastewater treatment plants in the US and implications for risk estimation

    Science.gov (United States)

    We measured the concentrations of 56 active pharmaceutical ingredients (APIs) and seven metabolites, including 50 prioritized APIs, in 24-hour composite effluent samples collected from 50 very large municipal wastewater treatment plants across the US. Hydrochlorothiazide was foun...

  1. Gene structure, phylogeny and expression profile of the sucrose ...

    Indian Academy of Sciences (India)

    Gene structure, phylogeny and expression profile of the sucrose synthase gene family in .... 24, 701–713. Bate N. and Twell D. 1998 Functional architecture of a late pollen .... Manzara T. and Gruissem W. 1988 Organization and expression.

  2. Fermentation of sugar beet molasses to alcohol

    Energy Technology Data Exchange (ETDEWEB)

    Semenets, P A

    1959-01-01

    Continuously operating equipment is described. The mode of operation is presented. It is possible to prepare 8.5 x 10/sup 4/ l. of ethanol and 12 to 14 long tons of high grade bakers' yeast in 24 hours.

  3. Desempenho de diferentes grupos genéticos de bovinos de corte em confinamento Performance evaluation of different beef cattle genetic groups under feedlot

    Directory of Open Access Journals (Sweden)

    Kepler Euclides Filho

    2003-10-01

    Full Text Available Foram utilizadas informações provenientes de 188 animais, pertencentes a dez grupos genéticos, avaliados em confinamento. Para as análises dos dados, os animais foram agrupados em três subconjuntos considerando-se idade, sexo e dieta recebida. Os subconjuntos analisados foram: 1 animais inteiros de sobreano recebendo a dieta "a": 39 Nelore (N, 12 Brangus (BR, 8 1/2 Simental-1/2 Nelore (SN, 8 1/2 Caracu-1/2 Nelore (CCN, 21 1/2 Valdostana-1/2 Nelore (VAN; 2 animais inteiros desmamados recebendo a dieta "b": 12 N, 12 1/2 Canchim-1/4 Angus-1/4 Nelore (CAN, 16 1/2 Canchim-1/4 Simental-1/4 Nelore (CSN, 12 1/2 Braford-1/2 Brangus (BDBR, 12 1/2 Braford-1/4 Angus-1/4 Nelore (BDAN, 7 1/2 Brahman-1/4 Angus-1/4 Nelore (BHAN; 3 fêmeas desmamadas recebendo a dieta "b" em duas formulações, uma em que o concentrado representou 30% da MS e o outro, em que o concentrado correspondeu a 50% da MS total. Neste caso, a análise incluiu 29 fêmeas, 15 CAN e 14 CSN. Para os animais dos subconjuntos 1 e 2, o concentrado foi fornecido para atender 50% da MS total da dieta. Os animais do subconjunto 1 apresentaram desempenhos semelhantes, com ganho de peso diário médio igual a 1,60 kg/dia e com conversão alimentar igual a 6,36 kg de MS ingerida/kg de ganho de peso. Para o ganho de peso diário médio e para a conversão alimentar, somente foram observadas diferenças entre os animais do subconjunto 2. O maior ganho de peso diário médio foi observado para os animais CSN (1,69 kg/dia e as melhores conversões alimentares foram verificadas para os animais CSN e BHAN (4,76 kg de MS ingerida/kg de ganho de peso e 4,67 kg de MS ingerida/kg de ganho de peso, respectivamente. Para o subconjunto 3 não houve diferenças entre os grupos genéticos, mas a formulação da dieta apresentou efeitos significativos importantes, especialmente, para conversão alimentar. Os animais da formulação com menor teor de concentrado apresentaram melhor conversão alimentar (5,58 kg

  4. Barriers professional competence and its relationship with job satisfaction of nurses' moral distress and pre-hospital emergency city of Bam and Jiroft in 1393

    Directory of Open Access Journals (Sweden)

    Mohammadjavad Rahimzadeh

    2016-05-01

    Full Text Available In order to "protect the health of people" Several organizations have been founded and given its role in saving lives when seconds play, is formed Medical Center Emergency Management Whose duty is satisfactory service in the shortest possible time. Because one of the pre-hospital emergency center nurses work centers and first deal with critical diseases carried by nurses, so they are faced with numerous obstacles which could impact on their job satisfaction has less moral distress. In this study, efficient professional barriers and its relation to moral distress and job satisfaction are studied prehospital emergency nurses. This study is a descriptive - correlation of prehospital emergency personnel Bam on 82 Jiroft who were selected by census was conducted. Data gathering questionnaire, including demographic characteristics, barriers to efficient professional, moral distress, job satisfaction after obtaining the appropriate reliability and validity were used. Analysis of the data in this study using SPSS version 18, using measures of central tendency and dispersion, t-test, Pearson correlation coefficient, ANOVA and regression analysis were used. According to the non-normal distribution efficiency and moral distress two variables obstacles relationship between these two variables with Spearman nonparametric Kruskal-Wallis test other variables and for other variables that were normally distributed parametric tests and ANOVA were used Pearson correlation coefficient. A total of 82 patients with mean age (31.54± 5.66 participated in th e study showed. Results are73.4% married, work experience, most people (% 91.5 were under 15 years old. Most people (52% with traffic and pedestrians as factors impeding efficient professional, fully agreed, the average score of moral distress (o.48 ± 2.13, the level of moral distress was most mid-level and job satisfaction 52. 4% of them were average. The results showed that between moral distress and job

  5. Long term follow up of medical therapy of thyroid cancer; Controle a long terme du traitement medical du cancer thyroidien differencie

    Energy Technology Data Exchange (ETDEWEB)

    Jaffiol, C.; Daures, J.P.; Nsakala, N.; Guerenova, J.; Baldet, L.; Pujol, P.; Vannereau, D.; Bringer, J. [Centre Hospitalier Universitaire, 34 - Montpellier (France)

    1995-12-31

    106 patients, 114 W, 27 M, were thyroidectomized for differentiated thyroid cancer (follicular 29.3% - papillary 54.3%) with different stages of gravity (N O: 48.2% - N 1: 32.8% - N 2: 19%). Neck dissection was used in cases of involved nodes. One or several doses of 131 I were given to 126 subjects, 106 patients were treated with L thyroxine (LT4) (mean daily dose: 2.5 {mu}g/kg BW). 23 patients presenting intolerance to LT4 with non suppressed TSH for 13 of them were treated by an association of tiratricol (TRIAC) + LT4. The follow up included a yearly check up involving clinical examination, plasma thyroglobulin (Tg) and thyroid stimulating hormone (TSH) assessment, neck ultrasonography and X ray of the chest. Therapy was stopped for 4 weeks in cases with Tg above its detectable value and a total body scan performed with Tg and TSH controls. The mean duration of follow up was 94.5 {+-} 67.7 months and extended to more than 5 years for 61% of the patients. We observed 22 relapses of the tumor with 4 deaths. Age less then 45 years, appears as the best factor of prognosis. 2 groups of patients were compared to evaluate the incidence of TSH suppression on the relapse free survival (group 1 n = 30 with a TSH {<=} 0.10 mU/1 and group 2 n = 15 with a TSH always > 1 mU/1 during the follow up). The relapse free survival was shorter in group 2 (p 0.01). Association of TRIAC with LT4 leads to a reduction of the daily dose of LT4 (m 25{mu}g/day) with a significant improvement of TSH suppression and clinical tolerance. In conclusion, TSH suppression improves the prognosis in thyroidectomized patients for differentiated carcinoma. Association of TRIAC with LT4 seems able to approve TSH suppression and therapeutic tolerance. (authors). 40 refs., 5 tabs.

  6. La historia de la colonia Lepida-Celsa según sus documentos numismáticos: su ceca imperial

    Directory of Open Access Journals (Sweden)

    García-Bellido, M. Paz

    2003-12-01

    Full Text Available The issues of Colonia Lepida allow us to propose the years 48-87 B.C. as its foundation date. The city, previously known by the Iberian name of Celsa, was changed to Lepida probably as a punishment for its support to the Pompeyan party. On 36 B.C. the colony regains its name Celsa. In 19 B.C. Agrippa stablishes here as imperial mint for aurei and denarii that had previously been adscribed to Caesarugusta, even though this city was then not yet founded. Judging by the circulation coinage and by the heavy metrology which lasts until Augustan times. Lepida seems to have coined bronze for military needs since Pompeyan issues.Las emisiones de Colonia Lepida permiten proponer el año 48-87 a.C. como la fecha de fundación de la colonia e interpretar la abolición del nombre de la ciudad ibérica Celsa como un castigo por su adhesión al bando pompeyano. En el 36 la ciudad recupera su nombre Celsa. En el 19 a.C. Agripa debe establecer en la colonia una ceca imperial que habíamos adscrito a Caesaraugusta, ciudad que todavía no estaba fundada, y provocar con ello una gran eclosión urbanística y política de Colonia Celsa. A juzgar por la circulación monetaria y la metrología uncial que se mantendrá hasta tiempos de Augusto, la ciudad parece, ya desde sus emisiones bilingües pompeyanas, haber abastecido de numerario de bronce a las tropas.

  7. Prevalence and factors associated with unmet need for family planning among the currently married reproductive age women in Shire-Enda- Slassie, Northern West of Tigray, Ethiopia 2015: a community based cross-sectional study.

    Science.gov (United States)

    Gebre, Gelawdiwos; Birhan, Nigussie; Gebreslasie, Kahsay

    2016-01-01

    Unmet family planning is one of the common causes for low contraceptive prevalence rate in developing countries including Ethiopia. Thus, this study designed to assess the prevalence and associated factors of unmet need in Shire Endaslassie town, Northern west of Tigray, Ethiopia. A community based cross sectional study design was employed. Multistage sampling technique was employed and data were collected using a semi-structured questionnaire by interviewer administered technique. Questionnaires were reviewed and checked for completeness, accuracy and consistency. Reviewed data were entered to Epi info 7 and analyzed by SPSS version 20 statistical software. Variables with P-value of less than 0.2 in bivariate analyses were entered for multivariate analysis and AOR at 95% CI with p-value of less than 0.05 were considered as significant variables. The overall unmet need for family planning in the study area was 109(21.4%). 74(14.5%) for spacing and 35(6.9%) for limiting. Age group of 35-39 and >=40 (AOR= 2.7,95%CI:1.1,6.5), (AOR = 2.65, 95%CI:1.10, 6.40) respectively, decided numbers of desired children more than five (AOR = O.48, 95%CI: 0.28, 0.80), discussions of client with heath care providers (AOR = 6.32, 95%CI: 2.56, 15.58), previous use of modern family planning (AOR = 2.29, 95%CI, 1.20, 4.34) were significantly associated with unmet need for family planning. Unmet need for family planning in the study area was high, so continuous discussion on modern family planning with community health workers and encouraging of women to decide desired numbers of children of less than five in general are better to be strengthened.

  8. Study of 16O-induced deep inelastic nuclear reactions on 27Al, 48Ti, and 58Ni by spectroscopy of the gamma radiation from the reaction products

    International Nuclear Information System (INIS)

    Puchta, H.

    1980-01-01

    The present thesis deals with the spectroscopy of the gamma radiation from the reaction fragments after binary reactions in the systems 16 O + 27 Al, 48 Ti, and 58 Ni at incident energies from 90 to 100 MeV, i.e. far above the Coulomb threshold. ΔE-E telescopes, which were located at 35 0 to the beam direction, detected the projectile-like fragments and defined the reaction channel and the scattering plane. In coincidence to this the gamma quanta in a 120-cm 3 -Ge(Li)-diode and a 27 x 33-cm-NaI-spectrometer were observed. The gamma spectra are equal to those observed hitherto in fusion reactions except for the high energetic gamma lines from the ejectiles, which are raised from the gamma continuum of the heavy fragments. From the spectroscoped gamma radiation for the light as for the heavy fragments the excitation energy, the value of the fragment angular momentum, as well as the occupation of the magnetic sublevels could be determined. The hard projectile 16 O transfers the dissipated energy and the angular momentum transferred by the spin of the fragments nearly completely into the residue nucleus. The probability for the observation of a ground state transition in one of the heavy fragments extends to (0.85 +- 0.10) per carbon ejectile in the system 16 O + 48 Ti. The residue nucleus distribution corresponds to that expected by the statistical model from the decay of the compound-nucleus 52 Cr belonging to the ejectile 12 C, the excitation energy of which corresponds to the reaction Q-value. (orig./HSI) [de

  9. Prevalência de sintomas depressivos e ansiosos em pacientes com dor crônica

    Directory of Open Access Journals (Sweden)

    Ricardo Cardoso Pinheiro

    2014-09-01

    Full Text Available Objetivos O presente estudo objetivou avaliar a prevalência de sintomas ansiosos e depressivos e relacioná-los com os diferentes tipos e magnitudes de dor crônica; também objetivou caracterizar a população de casos novos agendados para atendimento no ambulatório de dor crônica, no serviço onde o estudo foi realizado. Métodos Estudo de corte transversal, realizado em um ambulatório docente-assistencial para tratamento de dor crônica, realizado entre maio de 2012 e abril de 2013, com 125 pacientes. Instrumentos utilizados Questionário sociodemográfico, Escala Hospitalar de Ansiedade e Depressão (HAD e Escala Visual Numérica (EVN para aferir a intensidade de dor. Resultados Dor intensa foi referida por 64% (n = 80 dos pacientes. Ansiedade atingiu 65% (N = 82 dos pacientes e a depressão, 48% (N = 60. Houve correlação significante entre os mais altos escores de ansiedade (p < 0,001 e depressão (p < 0,001 com a intensidade de dor. A correlação entre intensidade de dor e sintomas ansiosos e depressivos foi positiva para dor crônica neuropática e mista. Os fatores sociodemográficos associados à intensidade de dor crônica foram: renda e religião para depressão, e tempo de dor para ansiedade. Conclusão O estudo mostrou elevada prevalência de sintomas depressivos e ansiosos em pacientes com dor crônica, assim como relação significante desses sintomas psiquiátricos com alguns tipos e intensidade de dor.

  10. Investigation of tritium and 233U breeding in a fission-fusion hybrid reactor fuelling with ThO2

    International Nuclear Information System (INIS)

    Yildiz, K.; Sahin, S.; Sahin, H. M.; Acir, A.; Yalcin, S.; Altinok, T.; Bayrak, M.; Alkan, M.; Durukan, O.

    2007-01-01

    In the world, thorium reserves are three times more than natural Uranium reserves. It is planned in the near future that nuclear reactors will use thorium as a fuel. Thorium is not a fissile isotope because it doesn't make fission with thermal neutrons so it could be converted to 2 33U isotope which has very high quality fission cross-section with thermal neutrons. 2 33U isotope can be used in present LWRs as an enrichment fuel. In the fusion reactors, tritium is the most important fossil fuel. Because tritium is not natural isotope, it has to be produced in the reactor. The purpose of this work is to investigate the tritium and 2 33U breeding in a fission-fusion hybrid reactor fuelling with ThO 2 for Δt=10 days during a reactor operation period in five years. The neutronic analysis is performed on an experimental hybrid blanket geometry. In the center of the hybrid blanket, there is a line neutron source in a cylindrical cavity, which simulates the fusion plasma chamber where high energy neutrons (14.1 MeV) are produced. The conventional fusion reaction delivers the external neutron source for blankets following, 2 D + 3 T →? 4 He (3.5 MeV) + n (14.1 MeV). (1) The fuel zone made up of natural-ThO 2 fuel and it is cooled with different coolants. In this work, five different moderator materials, which are Li 2 BeF 4 , LiF-NaF-BeF 2 , Li 2 0Sn 8 0, natural Lithium and Li 1 7Pb 8 3, are used as coolants. The radial reflector, called tritium breeding zones, is made of different Lithium compounds and graphite in sandwich structure. In the work, eight different Lithium compounds were used as tritium breeders in the tritium breeding zones, which are Li 3 N, Li 2 O, Li 2 O 2 , Li 2 TiO 3 , Li 4 SiO 3 , Li 2 ZrO 3 , LiBr and LiH. Neutron transport calculations are conducted in spherical geometry with the help of SCALE4.4A SYSTEM by solving the Boltzmann transport equation with code CSAS and XSDRNPM, under consideration of unresolved and resolved resonances, in S 8 -P 3

  11. Kvalitet og udvikling i socialpædagogisk arbejde med anbragte unge

    DEFF Research Database (Denmark)

    Aagerup, Lars

    2013-01-01

    for a quality development process. The investigation points to the following focus points in developing the quality in social pedagogy work with the young people in residential care: Including the young peoples´ life course perspective More focus on the employees´ use of power Including the young peoples´ own......This dissertation explores conceptions of quality in connection to the social educational work with young people in 24 hour care in Denmark, where about 12.000 children and young people are in 24 hour care. The aim of the investigations is to explore the possibilities of a qualitative...... and contextual approach in quality development in this area as an alternative to the general and quantitative approaches (Nygren 1999, Clarke 2003, Koslowski III 2006, Dahler Larsen 2008, Kroghstrup 2002 and 2011), as studies show poor results of the work with young people in 24 hour care (Egelund, Skovbo...

  12. Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade

    DEFF Research Database (Denmark)

    Aulinger, Benedikt A; Bedorf, Anne; Kutscherauer, Gabriele

    2014-01-01

    Understanding the incretin pathway has led to significant advancements in the treatment of type 2 diabetes (T2D). Still, the exact mechanisms are not fully understood. In a randomized, placebo-controlled, four-period, crossover study in 24 patients with T2D, dipeptidyl peptidase-4 (DPP-4) inhibit......Understanding the incretin pathway has led to significant advancements in the treatment of type 2 diabetes (T2D). Still, the exact mechanisms are not fully understood. In a randomized, placebo-controlled, four-period, crossover study in 24 patients with T2D, dipeptidyl peptidase-4 (DPP-4...

  13. Stone risk after bladder substitution with the ileal-urethral Kock reservoir

    DEFF Research Database (Denmark)

    Osther, P J; Poulsen, A L; Steven, K

    2000-01-01

    : The participants were 23 male patients who had undergone bladder substitution with the ileal-urethral Kock reservoir and 25 healthy men. All subjects had sterile urine at the time of urine collection. Concentrations of calcium, magnesium, phosphorus, creatinine, citrate, oxalate, and ammonia in 24-h urine samples...... were measured. Estimates of ion activity products of calcium oxalate (CaOx), calcium phosphate (CaP), brushite (Bru), and magnesium ammonium phosphate (MAP) in urine were calculated according to Tiselius. RESULTS: There was no significant difference in 24-h urinary volume between patients...

  14. An Examination of Issues Related to U.S. Lake Erie Natural Gas Development.

    Science.gov (United States)

    1978-09-01

    37 pg/mL 27 pg/mL 27 pg/mL 27 pg/mL detergent Wac-8 Talc & guar Non-toxic to 10,000 pg/mL in 24 hours gum Wac-10 Talc, silica Non-toxic to 10,000 ug...mL in 24 hours guar gum Fr-10 High molecu- Bioassay Method not applicable lar weight synthetic Fr-19 Polymer Bioassay Method not applicable aData from...Adeorption None Activated carbon. Activated carbon Activated carbon Activated carbon Activated carbon powdered Filtration Sandb Activated carbon. Sand Sand

  15. Immunotherapy of metastatic melanoma by reversal of immune suppression

    Energy Technology Data Exchange (ETDEWEB)

    Biggs, M.W.; Eiselein, J.E.

    1997-01-01

    Beginning with the observation that the human enteorvirus, Poliovirus Sabin 1, will lyse human melanoma cells in culture, clinical trials involving two patients with advance melanoma were performed. Parenteral injection of the viable Poliovirus into cutaneous melanoma metastases followed in 24 hours by oral administration of cyclophosphamide. The results of these two trials are described.

  16. Steady-state pharmacokinetics of pravastatin in children with familial hypercholesterolaemia

    NARCIS (Netherlands)

    Wiersma, Heleen E.; Wiegman, Albert; Koopmans, Richard P.; Bakker, Henk D.; Kastelein, John J. P.; van Boxtel, Chris J.

    2004-01-01

    Objective: To determine pharmacokinetic data for pravastatin in children, since current data are insufficient in this age group. Subjects and methods: A 2-week, multiple-dose, steady-state pharmacokinetic study was carried out with pravastatin 20mg daily in 24 children with familial

  17. Low-energy nuclear physics with high-segmentation silicon arrays

    International Nuclear Information System (INIS)

    Betts, R.R.; Univ. of Illinois, Chicago, IL

    1994-01-01

    A brief history is given of silicon detectors leading up to the development of ion-implanted strip detectors. Two examples of their use in low energy nuclear physics are discussed; the search for exotic alpha-chain states in 24 Mg and studies of anomalous positron-electron pairs produced in collisions of very heavy ions

  18. 24 CFR Appendix to Part 135 - Unknown Title

    Science.gov (United States)

    2010-04-01

    ... contract opportunities in a timely manner so that section 3 business concerns can take advantage of... low income persons by linking them to the support services available through the Small Business... each of the competitive procurement methods authorized in 24 CFR 85.36(d). (1) Small Purchase...

  19. Hyperoxaluria in idiopathic calcium nephrolithiasis--what are the limits?

    DEFF Research Database (Denmark)

    Osther, P J

    1999-01-01

    OBJECTIVE: The object of this study was to investigate the role for measurement of 24-h renal oxalate excretion in the evaluation of idiopathic calcium stone formers. MATERIALS AND METHODS: Renal excretion rates of oxalate and creatinine were measured in 24-h urines in 46 consecutive male recurrent...

  20. Evaluation of a semi-quantitative food frequency questionnaire to estimate iodine intake

    DEFF Research Database (Denmark)

    Rasmussen, Lone Banke; Ovesen, L.; Bulow, I.

    2001-01-01

    Objective: To evaluate a food frequency questionnaire (FFQ) used to assess the dietary intake of iodine. Design: The iodine intake determined by the FFQ was compared with 4-day dietary records and with iodine excretion in 24 h urine samples in a subgroup of participants in a cross-sectional study...

  1. Cognitive Disorders in Benign Childhood Epilepsy with Centrotemporal Spikes (BECTS

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2007-04-01

    Full Text Available Intelligence and language functions were examined in 24 children (mean age 9 yrs; range 7-12 yrs with BECTS and compared with a group of 16 controls matched for age and schooling, in a study at the Instituto Nazionale Neurologico, Milan, Italy.

  2. Lumbar myelography with omnipaque (iohexol)

    International Nuclear Information System (INIS)

    Lilleaas, F.; Weber, H.

    1986-01-01

    Lumbar myelography with iohexol (Omnipaque) was performed in 103 consecutive adult patients with low back pain or sciatica. The patients were observed for 48 h with registration of possible adverse reactions. Mild or moderate transient side effects were recorded in 24 patients. No serious adverse reactions were noted, and EEG recorded in 25 patients showed no changes. (orig.)

  3. Lumbar myelography with Omnipaque (iohexol)

    Energy Technology Data Exchange (ETDEWEB)

    Lilleaas, F.; Bach-Gansmo, T.; Weber, H.

    1986-07-01

    Lumbar myelography with iohexol (Omnipaque) was performed in 103 consecutive adult patients with low back pain or sciatica. The patients were observed for 48 h with registration of possible adverse reactions. Mild or moderate transient side effects were recorded in 24 patients. No serious adverse reactions were noted, and EEG recorded in 25 patients showed no changes.

  4. Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML

    DEFF Research Database (Denmark)

    Hasle, Henrik; Abrahamsson, Jonas; Forestier, Erik

    2012-01-01

    neutropenia followed 95% and febrile neutropenia 40% of the GO courses. Only a moderate decline in platelet count and a minor decrease in hemoglobin occurred. Relapse occurred in 24 and 25 of those randomized to GO or no further therapy. The median time to relapse was 16 months versus 10 months...

  5. Periodate and hypobromite modification of Southern pine wood to improve sorption of copper ion

    Science.gov (United States)

    James D. McSweeny; Roger M. Rowell; George C. Chen; Thomas L. Eberhardt; Min Soo-Hong

    2008-01-01

    Milled southern pine wood was modified with sequential treatments of sodium periodate and sodium hypobromite for the purpose of improving copper ion (Cu2+) sorption capacity of the wood when tested in 24-h equilibrium batch tests. The modified wood provided additional carboxyl groups to those in the native wood and substantially increased Cu2+ uptake over that of...

  6. Effect of citric acid modification of aspen wood on sorption of copper ion

    Science.gov (United States)

    James D. McSweeny; Roger M. Rowell; Soo Hong Min

    2006-01-01

    Milled aspen wood was thermochemically modified with citric acid for the purpose of improving the copper (Cu2+) ion sorption capacity of the wood when tested in 24-hour equilibrium batch tests. The wood-citric acid adducts provided additional carboxyl groups to those in the native wood and substantially increased Cu2+ ion uptake of the modified wood compared with that...

  7. Determination of coagulopathy complicating severe preeclampsia ...

    African Journals Online (AJOL)

    Preeclampsia is defined as gestational hypertension plus proteinuria of 300 mg or more in 24 hour urine sample collection or persistent proteinuria of at least 30 mg/dl (at least 1+ on dipstick) in random urine samples.[5] Eclampsia is defined as the onset of seizures and/or unexplained coma during pregnancy, intrapartum.

  8. Effect of lactic acid bacteria starter culture fermentation of cassava ...

    African Journals Online (AJOL)

    SERVER

    2007-08-20

    Aug 20, 2007 ... of cassava on chemical and sensory characteristics of fufu flour ... cassava fufu flour has the highest protein content; this shows the influence of fermentation in .... 24, 48, 72, and 96 h, during the natural fermentation of cassava ...

  9. Hydroxyapatite does not improve the outcome of a bipolar hemiarthroplasty.

    NARCIS (Netherlands)

    Meijerink, H.J.; Gardeniers, J.W.M.; Buma, P.; Lemmens, J.A.M.; Schreurs, B.W.

    2004-01-01

    In a one-surgeon study the clinical and radiographic results of 30 cementless bipolar hip prostheses in 24 patients younger than 55 years were evaluated. Eleven noncoated prostheses (Noncoated Group) and 19 hydroxyapatite-coated prostheses (Hydroxyapatite Group) were compared after a mean followup

  10. Thuisdealers, ritselaars en meesnoepers. Bewoners en bezoekers van grootstedelijke crackpanden

    NARCIS (Netherlands)

    Houwing, P.; Oteo Pérez, A.; Korf, D.J.

    2015-01-01

    This article is based on ethnographical research in 24 crack houses in Amsterdam, Rotterdam and The Hague. Crack houses were defined as the homes of crack users where crack is being sold and smoked together with other users. All crack houses were located in disadvantaged, multi-ethnic

  11. Regional cerebral blood flow distribution in newly diagnosed schizophrenia and schizophreniform disorder

    DEFF Research Database (Denmark)

    Rubin, P; Holm, S; Madsen, P L

    1994-01-01

    Regional cerebral blood flow distribution (rCBF) in 24 first admissions with schizophrenia or schizophreniform disorder and in 17 healthy volunteers was examined. Single photon emission computed tomography with a brain-retained tracer, technetium-99m-d,l-hexamethyl-propylene amine oxime, was used...... interrelationship in schizophrenia and schizophreniform disorder....

  12. Effect of growth hormone replacement therapy on plasma lecithin : cholesterol acyltransferase and lipid transfer protein activities in growth hormone-deficient adults

    NARCIS (Netherlands)

    Beentjes, JAM; van Tol, A; Sluiter, WJ; Dullaart, RPF

    The effects of growth hormone (GH) replacement on plasma lecithin:cholesterol acyltransferase (LCAT), cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP), factors involved in high density lipoprotein (HDL) metabolism, We unknown. We carried out a 6 mouths study in 24

  13. Comparing low frequency heart rate variability and preejection period: Two sides of a different coin.

    NARCIS (Netherlands)

    Goedhart, A.D.; Willemsen, G.; Houtveen, J.H.; Boomsma, D.I.; de Geus, E.J.C.

    2008-01-01

    It has been hypothesized that the ratio of heart rate variability in the low- (LF) and high- (HF) frequency bands may capture variation in cardiac sympathetic control. Here we tested the temporal stability of the LF/HF ratio in 24-h ambulatory recordings and compared this ratio to the preejection

  14. Effect of some botanical extracts on post-harvest losses of yam ...

    African Journals Online (AJOL)

    DR EZE

    2013-04-17

    Apr 17, 2013 ... losses of yam (Dioscorea rotundata) in improved yam ... two locations followed by A. indica while mean rot incidence was highest with no treatment control. In ... dissolved in 24 L of deionized water in a plastic bowl giving a.

  15. Continuous Adductor Canal Blocks

    DEFF Research Database (Denmark)

    Monahan, Amanda M; Sztain, Jacklynn F; Khatibi, Bahareh

    2016-01-01

    on cutaneous knee sensation in volunteers. METHODS: Bilateral adductor canal catheters were inserted in 24 volunteers followed by ropivacaine 0.2% administration for 8 hours. One limb of each subject was assigned randomly to a continuous infusion (8 mL/h) or automated hourly boluses (8 m...

  16. 24 CFR 597.3 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Definitions. 597.3 Section 597.3... COMMUNITY FACILITIES URBAN EMPOWERMENT ZONES AND ENTERPRISE COMMUNITIES: ROUND ONE DESIGNATIONS General Provisions § 597.3 Definitions. The terms HUD and Secretary are defined in 24 CFR part 5. Designation means...

  17. And justice for all : Examining corruption as a contextual source of mental illness

    NARCIS (Netherlands)

    van Deurzen, I.A.

    2017-01-01

    In the present study, I focus on the relationship between corruption and mental health as measured by the level of depressive symptoms. I use data collected by the European Social Survey in 2006, 2012 and 2014 from 99,159 individuals that lived in 24 European countries. I employ two types of

  18. VizieR Online Data Catalog: Photometry of 3 open clusters (Andreuzzi+, 2011)

    Science.gov (United States)

    Andreuzzi, G.; Bragaglia, A.; Tosi, M.; Marconi, G.

    2012-02-01

    Be20 and Be66 were observed with DOLORES at TNG (Telescopio Nazionale Galileo) in 24-Nov-2000 and 03-Oct-2000 (Be66); To2 was observed on 07-Mar-1995 (ESO/Danish), 15-May-2001 (ESO/Danish with DFOSC), and 15-Mar-2002 (ESO/NTT with SuSI2) (3 data files).

  19. Objective determination of pH thresholds in the analysis of 24 h ambulatory oesophageal pH monitoring

    NARCIS (Netherlands)

    Weusten, B. L.; Roelofs, J. M.; Akkermans, L. M.; vanBerge-Henegouwen, G. P.; Smout, A. J.

    1996-01-01

    In 24 h oesophageal pH monitoring, pH 4 is widely but arbitrarily used as the threshold between reflux and non-reflux pH values. The aim of the study was to define pH thresholds objectively, based on Gaussian curve fitting of pH frequency distributions. Single-channel 24 h oesophageal pH monitoring

  20. 24 CFR 266.510 - HFA responsibilities.

    Science.gov (United States)

    2010-04-01

    ... HOUSING FINANCE AGENCY RISK-SHARING PROGRAM FOR INSURED AFFORDABLE MULTIFAMILY PROJECT LOANS Project... accordance with the physical inspection procedures in 24 CFR part 5, subpart G. (b) Annual audits of projects. The HFA must analyze projects' annual audits and provide a copy to HUD along with a summary of...

  1. Holt Oram syndrome: a registry-based study in Europe

    DEFF Research Database (Denmark)

    Barisic, Ingeborg; Boban, Ljubica; Greenlees, Ruth

    2014-01-01

    were reported in all cases. Agenesis/hypoplasia of radius was present in 49.2% (30/61), ulnar aplasia/hypoplasia in 24.6% (15/61) and humerus hypoplasia/phocomelia in 42.6% (26/61) of patients. Congenital heart defects (CHD) were recorded in 78.7% (48/61) of patients. Isolated septal defects were...

  2. Identification of causes of unsafe acts or neglect resulting in roof or sidewall accidents.

    CSIR Research Space (South Africa)

    Hamilton-Atwell, A

    1997-10-01

    Full Text Available Despite all the attempts made to create a safe work environment for employees working in coals mines during the past nine years an average of 25 miners died every year, and 229 were injured. In 45% of the deaths and in 24% of the reported injuries...

  3. 24 CFR 92.356 - Conflict of interest.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Conflict of interest. 92.356... Development HOME INVESTMENT PARTNERSHIPS PROGRAM Other Federal Requirements § 92.356 Conflict of interest. (a... subrecipients, the conflict of interest provisions in 24 CFR 85.36 and 24 CFR 84.42, respectively, apply. In all...

  4. Having Their Song Heard: Tracking Pre-Service Kindergarten Teachers' Perceptions and Confidence in Their Singing Skills

    Science.gov (United States)

    Neokleous, Rania

    2013-01-01

    This paper reports a study investigating pre-service kindergarten teachers' confidence levels and perceptions regarding their singing skills, and the impact of a music methods course on these self-perceptions. The course incorporated singing instruction in 24 lectures and two 10-minute private singing tutorials at the beginning and middle of the…

  5. 76 FR 77842 - Announcement of Funding Awards; Indian Community Development Block Grant Program; Fiscal Year 2011

    Science.gov (United States)

    2011-12-14

    ... environments, and economic opportunities primarily for persons with low and moderate incomes as defined in 24... Pechonick Chief, 170 N.E. Infrastructure. Nutrition Kitchen. Barbara Avenue, Bartlesville, OK 74006, (918... 600,000 Public Facility Community Work Force Development Erma Vizenor, Chairperson, PO Box 418, Center...

  6. Days out of role due to common physical and mental conditions : results from the WHO World Mental Health surveys

    NARCIS (Netherlands)

    Alonso, J.; Petukhova, M.; Vilagut, G.; Chatterji, S.; Heeringa, S.; Uestuen, T. B.; Alhamzawi, A. O.; Viana, M. C.; Angermeyer, M.; Bromet, E.; Bruffaerts, R.; de Girolamo, G.; Florescu, S.; Gureje, O.; Haro, J. M.; Hinkov, H.; Hu, C-y; Karam, E. G.; Kovess, V.; Levinson, D.; Medina-Mora, M. E.; Nakamura, Y.; Ormel, J.; Posada-Villa, J.; Sagar, R.; Scott, K. M.; Tsang, A.; Williams, D. R.; Kessler, R. C.; Ustun, T.B.; de, Girolamo G.

    2011-01-01

    Days out of role because of health problems are a major source of lost human capital. We examined the relative importance of commonly occurring physical and mental disorders in accounting for days out of role in 24 countries that participated in the World Health Organization (WHO) World Mental

  7. Turning the Tide: Five Years of Achieving the Dream in Community Colleges

    Science.gov (United States)

    Rutschow, Elizabeth Zachry; Richburg-Hayes, Lashawn; Brock, Thomas; Orr, Genevieve; Cerna, Oscar; Cullinan, Dan; Kerrigan, Monica Reid; Jenkins, Davis; Gooden, Susan; Martin, Kasey

    2011-01-01

    In 2004, Lumina Foundation for Education launched "Achieving the Dream: Community Colleges Count," a national initiative aimed at improving success among community college students, particularly low-income students and students of color. Now encompassing more than 130 institutions in 24 states and the District of Columbia, Achieving the…

  8. Environmental income and rural livelihoods

    DEFF Research Database (Denmark)

    Angelsen, Arild; Jagger, Pamela; Babigumira, Ronnie

    2014-01-01

    This paper presents results from a comparative analysis of environmental income from approximately 8000 households in 24 developing countries collected by research partners in CIFOR’s Poverty Environment Network (PEN). Environmental income accounts for 28% of total household income, 77% of which ...

  9. Scholarly Productivity in Communication Studies: Five-Year Review 2012-2016

    Science.gov (United States)

    Griffin, Darrin J.; Bolkan, San; Dahlbach, Barbara J.

    2018-01-01

    This study reports prolific scholarship trends in communication studies based on individual publication rates in 24 journals from the field for the years 2012-2016. In addition, we summarized data from a subset of journals considered to be most central to our discipline ("Human Communication Research, Communication Research, Communication…

  10. 24 CFR 92.2 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... with local or other applicable regulations or is not in compliance with State, local, or model building... in 24 CFR 570.3. Neighborhood means a geographic location designated in comprehensive plans...-direction, capacity for independent living, and economic self-sufficiency; and (v) Reflects the person's...

  11. The OSHA Communication Standard and State Right-to-Know Laws.

    Science.gov (United States)

    Roll, Michalene H.

    1990-01-01

    As a result of a 1988 federal appellate court mandate, schools and colleges in 24 states and 2 territories with OSHA-approved state plans must inform their employees about hazardous chemicals to which they may be exposed. School administrators should implement a responsible program meeting regulatory compliance, tort liability, and public…

  12. Hemispheric Processing of Idioms and Irony in Adults with and without Pervasive Developmental Disorder

    Science.gov (United States)

    Saban-Bezalel, Ronit; Mashal, Nira

    2015-01-01

    Previous studies on individuals with pervasive developmental disorders (PDD) have pointed to difficulties in comprehension of figurative language. Using the divided visual field paradigm, the present study examined hemispheric processing of idioms and irony in 23 adults with PDD and in 24 typically developing (TD) adults. The results show that…

  13. Radiologic semiotics of cholelithiasis in direct contarst of the biliary tracts

    International Nuclear Information System (INIS)

    Bulatov, N.N.; Chernekhovskaya, N.E.; Erokhin, P.G.; Rozikov, Yu.Sh.

    1982-01-01

    A newly developed method of the gallbladder transhepatic drainage during laparoscopy with subsequent direct radiocontrast examination was applied to 61 cholelithiasis patients. The stones of the gallbladder and the cystic duct were detected in 20 patients, of the gallbladder and the common bile duct - in 24, and both solitary and multiple stones of the common bile duct - in 17

  14. 24 CFR 984.103 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... earnings included in annual income from wages, tips, salaries, other employee compensation, and self... Partnership Act (29 U.S.C. 1579(a)). Low-income family. As defined in part 5 of this title. Participating.... Very low-income family. See definitions in 24 CFR 813.102 and 913.102. Welfare assistance means (for...

  15. Anxiety and blood pressure prior to dental treatment.

    NARCIS (Netherlands)

    Benjamins, C.; Schuurs, A.H.; Asscheman, H.; Hoogstraten, J.

    1990-01-01

    Assessed dental anxiety and blood pressure immediately prior to a dental appointment in 24 patients attending a university dental clinic or a clinic for anxious dental patients in the Netherlands. Blood pressure was assessed by 2 independent methods, and the interchangeability of the blood-pressure

  16. Small, Task-Oriented Groups: Conflict, Conflict Management, Satisfaction, and Decision Quality.

    Science.gov (United States)

    Wall, Victor D., Jr.; And Others

    1987-01-01

    Examined relationship among amount of conflict experienced, the style of its management, individual satisfaction, and decision quality of small, task-oriented groups using 129 college student subjects in 24 groups. Data suggest a curvilinear relationship between the number of conflict episodes experienced by group members and the subsequent…

  17. Where Nursing Counts. Careers for Nurses in the Indian Health Service.

    Science.gov (United States)

    Public Health Service (DHEW), Rockville, MD. Indian Health Service.

    To meet the health needs of Native Americans, the Indian Health Service (IHS) administers a large community health and medical care program, operating 51 hospitals, 99 health care centers, and 108 health stations in 24 states. Registered nurses can be employed by the IHS through either of two systems: the Commissioned Corps of the U.S. Public…

  18. Eccentric exercise training in patients with chronic obstructive pulmonary disease.

    NARCIS (Netherlands)

    Rooyackers, J.M.; Berkeljon, D.A.; Folgering, H.T.M.

    2003-01-01

    The oxygen cost of eccentric exercise is lower than that of concentric exercise at similar work-loads. In this study, the response to eccentric cycle exercise training (EET) in addition to general exercise training (GET) on exercise performance and quality of life was investigated in 24 patients

  19. 24 CFR 585.503 - Conflict of interest.

    Science.gov (United States)

    2010-04-01

    ... the nature of the conflict, accompanied by an assurance that there has been public disclosure of the... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Conflict of interest. 585.503... § 585.503 Conflict of interest. (a)(1) In addition to the conflict of interest requirements in 24 CFR...

  20. Whipple's operation for carcinoma of the pancreatic head and the ampullary region. Short-and long-term results

    DEFF Research Database (Denmark)

    Sørensen, M B; Banner, Jytte; Rokkjaer, M

    1998-01-01

    In this retrospective review short- and long-term perspectives have been evaluated for 108 patients who, during 1982 through 1992, had Whipple's operation performed for carcinoma of the pancreatic head (PC, n=63) or the ampullary region (AC, n=45). In 24 patients the operation was not radical (21...

  1. Cardiac anomalies in individuals with the 18q deletion syndrome; report of a child with Ebstein anomaly and review of the literature

    NARCIS (Netherlands)

    Trier, D.C. van; Feenstra, I.; Bot, P.; Leeuw, N. de; Draaisma, J.M.T.

    2013-01-01

    Individuals with the 18q deletion syndrome are presented with various clinical characteristics, including cardiac anomalies in 24-36% of the reported cases. Nonetheless, genotype-phenotype correlations for cardiac anomalies in the 18q deletion syndrome have rarely been reported. We report on two

  2. Approach to cardiac resyncronization therapy

    DEFF Research Database (Denmark)

    Dobreanu, Dan; Dagres, Nikolaos; Svendsen, Jesper Hastrup

    2012-01-01

    fibrillation and standard criteria for CRT. In 24% of the centres, biventricular pacemaker (CRT-P) is implanted in all situations, unless there is an indication for secondary prevention of sudden cardiac death, while 10% always choose to implant a biventricular defibrillator (CRT-D). There are no clear...

  3. Protein profiles of serum, brain regions and hypophyses of pubertal ...

    African Journals Online (AJOL)

    The effects of dietary fumonisin B1 (FB1 ), a toxin produced mainly by Fusarium verticillioides and F. proliferatum that grow on maize worldwide, on protein profiles of serum, brain regions and hypophyses were studied in 24 male Large White weanling pigs randomly divided into four groups (n = 6). In a completely ...

  4. Exploring Neutron-Rich Oxygen Isotopes with MoNA

    International Nuclear Information System (INIS)

    Frank, N.; Gade, A.; Peters, W. A.; Thoennessen, M.; Baumann, T.; Bazin, D.; Lecouey, J.-L.; Scheit, H.; Schiller, A.; Brown, J.; DeYoung, P. A.; Finck, J. E.; Hinnefeld, J.; Howes, R.; Luther, B.

    2007-01-01

    The Modular Neutron Array (MoNA) was used in conjunction with a large-gap dipole magnet (Sweeper) to measure neutron-unbound states in oxygen isotopes close to the neutron dripline. While no excited states were observed in 24 O, a resonance at 45(2) keV above the neutron separation energy was observed in 23 O

  5. Estimation of amputation level with a laser Doppler flowmeter

    DEFF Research Database (Denmark)

    Gebuhr, Peter Henrik; Jørgensen, J P; Vollmer-Larsen, B

    1989-01-01

    Leg amputation levels were decided in 24 patients suffering from atherosclerosis, using the conventional techniques of segmental blood pressure and radioisotope skin clearance. The skin microcirculation was measured and recorded before operation with a laser doppler flowmeter. A high correlation...... was found between the successful amputation levels and the maximal blood perfusion of the skin measured in this way....

  6. Mutation and biochemical analysis in carnitine palmitoyltransferase type II (CPT II) deficiency

    DEFF Research Database (Denmark)

    Olpin, S E; Afifi, A; Clark, S

    2003-01-01

    Carnitine palmitoyltransferase type II (CPT II) deficiency has three basic phenotypes, late-onset muscular (mild), infantile/juvenile hepatic (intermediate) and severe neonatal. We have measured fatty acid oxidation and CPT II activity and performed mutation studies in 24 symptomatic patients...

  7. 24 CFR 570.613 - Eligibility restrictions for certain resident aliens.

    Science.gov (United States)

    2010-04-01

    ... certain resident aliens. 570.613 Section 570.613 Housing and Urban Development Regulations Relating to... GRANTS Other Program Requirements § 570.613 Eligibility restrictions for certain resident aliens. (a) Restriction. Certain newly legalized aliens, as described in 24 CFR part 49, are not eligible to apply for...

  8. Elementary School Organization: Self-Contained and Departmentalized Classroom Structures.

    Science.gov (United States)

    Des Moines Public Schools, IA.

    Surveys were conducted to investigate contemporary thought regarding organizational practices at the elementary level, with particular attention to identifying the extent to which departmentalization was supported by research and actually employed in 24 elementary schools in the Midwest and in 41 Des Moines elementary schools. Four committees…

  9. Changes in energy metabolism in response to 48 h of overfeeding and fasting in Caucasians and Pima Indians

    DEFF Research Database (Denmark)

    Weyer, C; Vozarova, B; Ravussin, E

    2001-01-01

    Differences in the metabolic response to overfeeding and starvation may confer susceptibility or resistance to obesity in humans. To further examine this hypothesis, we assessed the changes in 24 h energy metabolism in response to short-term overfeeding and fasting in Caucasians (C) and Pima...... Indians (I), a population with a very high propensity for obesity....

  10. Genome-wide association study of prostate cancer-specific survival

    DEFF Research Database (Denmark)

    Szulkin, Robert; Karlsson, Robert; Whitington, Thomas

    2015-01-01

    BACKGROUND: Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical. METHODS: We performed a genome-wide survival analysis of cause-specific death in 24,...

  11. Efficacy of Atomoxetine for the Treatment of ADHD Symptoms in Patients with Pervasive Developmental Disorders: A Prospective, Open-Label Study

    Science.gov (United States)

    Fernandez-Jaen, Alberto; Fernandez-Mayoralas, Daniel Martin; Calleja-Perez, Beatriz; Munoz-Jareno, Nuria; Campos Diaz, Maria del Rosario; Lopez-Arribas, Sonia

    2013-01-01

    Objective: Atomoxetine's tolerance and efficacy were studied in 24 patients with pervasive developmental disorder and symptoms of ADHD. Method: Prospective, open-label, 16-week study was performed, using the variables of the Clinical Global Impression Scale and the Conners' Scale, among others. Results: A significant difference was found between…

  12. International Comparisons of Behavioral and Emotional Problems in Preschool Children: Parents' Reports from 24 Societies

    Science.gov (United States)

    Rescorla, Leslie A.; Achenbach, Thomas M.; Ivanova, Masha Y.; Harder, Valerie S.; Otten, Laura; Bilenberg, Niels; Bjarnadottir, Gudrun; Capron, Christiane; De Pauw, Sarah S. W.; Dias, Pedro; Dobrean, Anca; Dopfner, Manfred; Duyme, Michel; Eapen, Valsamma; Erol, Nese; Esmaeili, Elaheh Mohammad; Ezpeleta, Lourdes; Frigerio, Alessandra; Fung, Daniel S. S.; Goncalves, Miguel; Gudmundsson, Halldor; Jeng, Suh-Fang; Jusiene, Roma; Kim, Young Ah; Kristensen, Solvejg; Liu, Jianghong; Lecannelier, Felipe; Leung, Patrick W. L.; Machado, Barbara Cesar; Montirosso, Rosario; Oh, Kyung Ja; Ooi, Yoon Phaik; Pluck, Julia; Pomalima, Rolando; Pranvera, Jetishi; Schmeck, Klaus; Shahini, Mimoza; Silva, Jaime R.; Simsek, Zeynep; Sourander, Andre; Valverde, Jose; van der Ende, Jan; Van Leeuwen, Karla G.; Wu, Yen-Tzu; Yurdusen, Sema; Zubrick, Stephen R.; Verhulst, Frank C.

    2011-01-01

    International comparisons were conducted of preschool children's behavioral and emotional problems as reported on the Child Behavior Checklist for Ages 1 1/2-5 by parents in 24 societies (N = 19,850). Item ratings were aggregated into scores on syndromes; "Diagnostic and Statistical Manual of Mental Disorders"-oriented scales; a Stress…

  13. Fifteenth Annual Rank-Order Distribution of Administrative Salaries Paid, 1981-1982.

    Science.gov (United States)

    Arkansas Univ., Fayetteville. Office of Institutional Research.

    Administrative salaries in 1981-82 in 132 state-supported universities in 45 states and 31 university systems in 24 states were surveyed. Only full-time administrators were included but their responsibilities and functions range from the director of a single office to the university president. To provide anonymity, the universities are not…

  14. Attributing foodborne salmonellosis in humans to animal reservoirs in the European Union using a multi-country stochastic model

    DEFF Research Database (Denmark)

    de Knegt, Leonardo; Pires, Sara Monteiro; Hald, Tine

    2015-01-01

    A Bayesian modelling approach comparing the occurrence of Salmonella serovars in animals and humans was used to attribute salmonellosis cases to broilers, turkeys, pigs, laying hens, travel and outbreaks in 24 European Union countries. Salmonella data for animals and humans, covering the period f......, highlighting differences in the epidemiology of Salmonella, surveillance focus and eating habits across the European Union....

  15. Thalamic glucose metabolism in temporal lobe epilepsy measured with 18F-FDG positron emission tomography (PET)

    NARCIS (Netherlands)

    Khan, N; Leenders, KL; Hajek, M; Maguire, P; Missimer, J; Wieser, HG

    1997-01-01

    Thalamic glucose metabolism has been studied in 24 patients suffering from temporal lobe epilepsy (TLE) using interictal F-18-fluorodeoxyglucose (FDG) positron emission tomography (PET). A total of 17 patients had a unilateral TL seizure onset, 11 of these patients had a mesial temporal lobe

  16. Search for C+ C clustering in Mg ground state

    Indian Academy of Sciences (India)

    2017-01-04

    Jan 4, 2017 ... Finite-range knockout theory predictions were much larger for (12C,212C) reaction, indicating a very small 12C−12C clustering in 24Mg. (g.s.) . Our present results contradict most of the proposed heavy cluster (12C+12C) structure models for the ground state of 24Mg. Keywords. Direct nuclear reactions ...

  17. Experiment list: SRX810435 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available idity in Shneider S2 Drosophila medium(Gibco) supplement...ster; ChIP-Seq source_name=Cell culture || cell line=S2 || chip antibody=none || growth protocol=S2 cells were grown in 24°C, 95% hum

  18. Experiment list: SRX810433 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available er; ChIP-Seq source_name=Cell culture || cell line=S2 || chip antibody=none || growth protocol=S2 cells were grown in 24°C, 95% humid...ity in Shneider S2 Drosophila medium(Gibco) supplemented

  19. Experiment list: SRX810434 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available idity in Shneider S2 Drosophila medium(Gibco) supplement...ster; ChIP-Seq source_name=Cell culture || cell line=S2 || chip antibody=none || growth protocol=S2 cells were grown in 24°C, 95% hum

  20. Conformity to Peer Pressure in Preschool Children

    Science.gov (United States)

    Haun, Daniel B. M.; Tomasello, Michael

    2011-01-01

    Both adults and adolescents often conform their behavior and opinions to peer groups, even when they themselves know better. The current study investigated this phenomenon in 24 groups of 4 children between 4;2 and 4;9 years of age. Children often made their judgments conform to those of 3 peers, who had made obviously erroneous but unanimous…

  1. 24 CFR 92.258 - Elder cottage housing opportunity (ECHO) units.

    Science.gov (United States)

    2010-04-01

    ... designed to be installed adjacent to existing single-family dwellings. (b) Eligible owners. The owner of a HOME-assisted ECHO unit may be: (1) The owner-occupant of the single-family host property on which the... elderly or disabled family as defined in 24 CFR 5.403 and must also be a low-income family. (d) Applicable...

  2. Caregiver Cognition and Behavior in Day-Care Classrooms.

    Science.gov (United States)

    Holloway, Susan D.

    A study examined the relationship between change in daycare children's classroom behavior and the teacher's socialization behavior. Various behaviors of 69 children in 24 classrooms were observed and coded in the fall and spring of the school year. Observers coded teacher behavior according to the Caregiver Interaction Scale, which assesses…

  3. People’s Republic of China Scientific Abstracts, Number 170

    Science.gov (United States)

    1977-06-30

    ORO: Wong-sze Hosoital, Nan-p’i County, Ho-pei TITLE: "Use of Bleomycin Eyedrops in the Prevention of Postoperative Recurrence of Pannus " SOTTRCE...to prevent postoperative recurrence of pannus . It was used in 24 e^es (2 had 3 recurrences). All cases were operated by the D’ombrain orocedure

  4. Effects of land use/cover change and harvests on forest carbon dynamics in northern states of the United States from remote sensing and inventory data: 1992-2001

    Science.gov (United States)

    Daolan Zheng; Linda S. Heath; Mark J. Ducey; James E. Smith

    2011-01-01

    We examined spatial patterns of changes in forest area and nonsoil carbon (C) dynamics affected by land use/cover change (LUC) and harvests in 24 northern states of the United States using an integrated methodology combining remote sensing and ground inventory data between 1992 and 2001. We used the Retrofit Change Product from the Multi-Resolution Land Characteristics...

  5. Children and Modern Day Slavery

    African Journals Online (AJOL)

    DrNneka

    It decries the varied proliferation of Child Slavery to this modern day .... Children are forced to work long hours in mines for little to no pay. They toil in 24 ..... of child in mines, quarries and mechanical and engineering workshops, imposition of.

  6. 24 CFR 200.6 - Employer identification and social security numbers.

    Science.gov (United States)

    2010-04-01

    ... identification and social security numbers. The requirements set forth in 24 CFR part 5, regarding the disclosure and verification of social security numbers and employer identification numbers by applicants and... security numbers. 200.6 Section 200.6 Housing and Urban Development Regulations Relating to Housing and...

  7. 24 CFR 242.68 - Disclosure and verification of Social Security and Employer Identification Numbers.

    Science.gov (United States)

    2010-04-01

    ... Social Security and Employer Identification Numbers. 242.68 Section 242.68 Housing and Urban Development... Requirements § 242.68 Disclosure and verification of Social Security and Employer Identification Numbers. The requirements set forth in 24 CFR part 5, regarding the disclosure and verification of Social Security Numbers...

  8. Snake bite in southern Africa: diagnosis and management

    African Journals Online (AJOL)

    mask or nasal catheters, and establishment of intravenous access. Fig. 21. ... However, patients with an atopic history and those with a history of previous reactions to .... If the urine output falls below 400 ml in 24 hours, central venous pressure ...

  9. Gabapentin in procedure-specific postoperative pain management

    DEFF Research Database (Denmark)

    Fabritius, Maria Louise; Geisler, Anja; Petersen, Pernille Lykke

    2017-01-01

    in 24-h morphine consumption, and serious adverse events (SAE) between surgical procedures. These subgroup analyses were predefined in a PRISMA compliant systematic review registered at PROSPERO (ID: CRD42013006538). It was predefined that conclusions should primarily be based on trials classified...

  10. Gabapentin for post-operative pain management - a systematic review with meta-analyses and trial sequential analyses

    DEFF Research Database (Denmark)

    Fabritius, M L; Geisler, A; Petersen, P L

    2016-01-01

    ). The primary outcomes were 24-h opioid consumption and incidence of serious adverse events (SAE). RESULTS: One hundred and thirty-two trials with 9498 patients were included. Thirteen trials with low risk of bias reported a reduction in 24-h opioid consumption of 3.1 mg [0.5, 5.6; TSA-adjusted CI: -0.2, 6...

  11. Anal wall sparing effect of an endorectal balloon in 3D conformal and intensity-modulated prostate radiotherapy.

    NARCIS (Netherlands)

    Smeenk, R.J.; Lin, E.N.J.T. van; Kollenburg, P. van; Kunze-Busch, M.C.; Kaanders, J.H.A.M.

    2009-01-01

    BACKGROUND AND PURPOSE: To investigate the anal wall (Awall) sparing effect of an endorectal balloon (ERB) in 3D conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) for prostate cancer. MATERIALS AND METHODS: In 24 patients with localized prostate carcinoma, two planning

  12. Measurement of intestinal permeability using 51Cr-EDTA

    International Nuclear Information System (INIS)

    Peled, Y.; Watz, C.; Gilat, T.

    1985-01-01

    Intestinal permeability tests are a new class of tests of which the 51 Cr-EDTA seemed the easiest to perform. The authors have evaluated the 8- and 24-h urinary excretion of ingested 51 Cr-EDTA in 38 subjects. Twenty-seven patients with diseases not affecting the integrity of the small bowel served as controls. The test group consisted of two patients with celiac, six with Crohn's disease, and three with ulcerative colitis. Nineteen (70.37%) of the control patients had an abnormal test (more than 2.6% in 24 h). The patients with ulcerative colitis had normal excretion (mean 1.95% in 24 h). The patients with celiac disease had an elevated excretion (mean 3.62% in 24 h) and five out of six patients with Crohn's disease also had an increased excretion (mean 6.2% in 24 h). The elevated 51 Cr-EDTA excretion in the control patients casts serious doubts on the validity of the test. Possible causes for abnormal excretion in the controls include various medications used by the patients as well as changes in the chromatographic mobility of 51 Cr-EDTA, demonstrated after incubation with gastric juice

  13. Transcutaneous port for levodopa/carbidopa intestinal gel administration in Parkinson's disease

    NARCIS (Netherlands)

    van Laar, T.; Nyholm, D.; Nyman, R.

    Objective - To evaluate the safety and tolerability of the T-Port (R) for intestinal infusion of levodopa/carbidopa gel in patients with advanced Parkinson's disease (PD). Methods - This prospective study was carried out in 24 patients with PD (15 males, mean age 61.8 years, mean duration PD 18.7

  14. Investigation of Galactosylated Low Molecular Weight Chitosan ...

    African Journals Online (AJOL)

    Gal-LMWC(s)-coated liposomes exhibited a maximum of 65 % in vitro drug release in 24 h in a sustained fashion. The 50 % inhibitory concentration (IC50) values for liposomal formulations and drug solution were 2.81 and 5.98 μg/ml, respectively. Conclusion: Gal-LMWC (s) coated liposomes containing DOX that ...

  15. Evidence for genetic heterogeneity in D-2-hydroxyglutaric aciduria

    DEFF Research Database (Denmark)

    Kranendijk, Martijn; Struys, Eduard A; Gibson, K Michael

    2010-01-01

    We performed molecular, enzyme, and metabolic studies in 50 patients with D-2-hydroxyglutaric aciduria (D-2-HGA) who accumulated D-2-hydroxyglutarate (D-2-HG) in physiological fluids. Presumed pathogenic mutations were detected in 24 of 50 patients in the D-2-hydroxyglutarate dehydrogenase (D2HGD...

  16. Morphosyntax and Logical Abilities in Italian Poor Readers: The Problem of SLI Under-Identification

    Science.gov (United States)

    Arosio, Fabrizio; Pagliarini, Elena; Perugini, Maria; Barbieri, Lina; Guasti, Maria Teresa

    2016-01-01

    The study investigated morphosyntactic abilities and semantic-pragmatic competence in 24 children with developmental dyslexia aged 7-12 years. Morphosyntactic abilities were investgated in a direct object clitic production task, semantic-pragmatic competence in a quantifier comprehension task. Children with dyslexia produced fewer clitics than…

  17. 24 CFR 891.155 - Other Federal requirements.

    Science.gov (United States)

    2010-04-01

    ... and mechanics (other than volunteers under the conditions set out in 24 CFR part 70) employed by... employment of laborers and mechanics shall be subject to the provisions of the Contract Work Hours and Safety... displaced person must be provided relocation assistance at the levels described in, and in accordance with...

  18. 24 CFR 982.316 - Live-in aide.

    Science.gov (United States)

    2010-04-01

    ... withdraw such approval, if: (1) The person commits fraud, bribery or any other corrupt or criminal act in... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Live-in aide. 982.316 Section 982... connection with Section 8 or public housing assistance under the 1937 Act. [63 FR 23860, Apr. 30, 1998; 63 FR...

  19. Moldicidal properties of seven essential oils

    Science.gov (United States)

    Vina W. Yang; Carol A. Clausen

    2006-01-01

    When wood and wood products are exposed to moisture during storage, construction or while in-service, mold growth can occur in 24 to 48 hours. Mold growth could be suppressed or prevented if wood was treated with an effective mold inhibitor. The objective of this study was to evaluate the mold inhibiting properties of natural plant extracts such as essential oils....

  20. The Role of Physical Education Lessons and Recesses in School Lifestyle of Adolescents

    Science.gov (United States)

    Frömel, Karel; Svozil, Zbynek; Chmelík, František; Jakubec, Lukáš; Groffik, Dorota

    2016-01-01

    Background: This study investigates school lifestyle among adolescents in terms of physical activity (PA) structure: (1) adolescents participating in a physical education lesson (PEL) versus (2) aggregate recess time exceeding 60 minutes. Methods: The research was conducted in 24 secondary schools in the Czech Republic (boys N = 208, girls N =…

  1. 24 CFR 941.209 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 941.209 Section 941.209... HOUSING DEVELOPMENT PHA Eligibility and Program Requirements § 941.209 Audit. All PHAs that receive funds under this part for the development of low-income housing shall comply with audit requirements in 24 CFR...

  2. 24 CFR 886.336 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 886.336 Section 886.336... the Disposition of HUD-Owned Projects § 886.336 Audit. (a) Where a State or local government is the eligible owner of a project receiving financial assistance under this part, the audit requirements in 24...

  3. 24 CFR 884.124 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 884.124 Section 884.124... HOUSING PROJECTS Applicability, Scope and Basic Policies § 884.124 Audit. (a) Where a State or local..., receiving financial assistance under this part, the audit requirements in 24 CFR part 44 shall apply. (b...

  4. 24 CFR 883.313 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 883.313 Section 883.313... § 883.313 Audit. (a) Where housing assistance under the Section 8 Program is provided for projects developed by State agencies, these agencies shall follow audit requirements in 24 CFR part 44. (b) Where a...

  5. 24 CFR 886.131 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 886.131 Section 886.131... Projects With HUD-Insured and HUD-Held Mortgages § 886.131 Audit. (a) Where a State or local government is... assistance under this part, the audit requirements in 24 CFR part 44 shall apply. (b) Where a nonprofit...

  6. 24 CFR 882.124 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 882.124 Section 882.124...) SECTION 8 MODERATE REHABILITATION PROGRAMS Applicability, Scope and Basic Policies § 882.124 Audit. PHAs receiving financial assistance under this part are subject to audit requirements in 24 CFR part 44. [50 FR...

  7. 24 CFR 214.500 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Audit. 214.500 Section 214.500... PROGRAM Other Federal Requirements § 214.500 Audit. Housing counseling grant recipients and subrecipients shall be subject to the audit requirements contained in 24 CFR parts 84 and 85. HUD must be provided a...

  8. 24 CFR 880.211 - Audit.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 880.211 Section 880.211... § 880.211 Audit. (a) Where a State or local government is the eligible owner of a project or a contract administrator under § 880.505 receiving financial assistance under this part, the audit requirements in 24 CFR...

  9. Selecting Pesticides and Nonchemical Alternatives: Green Thumbs' Rules of Thumb Decision Tools.

    Science.gov (United States)

    Grieshop, James I.; And Others

    1992-01-01

    A sample of 78 (of 320) home gardeners use rules of thumb (heuristics) to choose between chemical pesticides and nonchemical alternatives. Pesticides rank low in 24 choice attributes where alternatives rank high, and vice versa. Gender, age, and years of pesticide use correlate with pesticide selection. (SK)

  10. Fault Tolerant Paradigms

    Science.gov (United States)

    2016-02-26

    ln d ) -time in that case.14 We prove Theorem 7 by following the generic compressive phase retrieval recipe presented in [24]. Let C ∈ Cm×d be any...retrieval, available online: arXiv:1312.0158. [20] S. Cook , The P versus NP problem, available online: http://www.claymath.org/millennium/PvsNP

  11. A Preliminary Study of Gender Differences in Autobiographical Memory in Children with an Autism Spectrum Disorder

    Science.gov (United States)

    Goddard, Lorna; Dritschel, Barbara; Howlin, Patricia

    2014-01-01

    Autobiographical memory was assessed in 24 children (12 male, 12 female, aged between 8 and 16 years) with autism spectrum disorder (ASD) and a comparison group of 24 typically developing (TD) children matched for age, IQ, gender and receptive language. Results suggested that a deficit in specific memory retrieval in the ASD group was more…

  12. Preparative-scale separation of C60 and C70 on polystyrene gel

    International Nuclear Information System (INIS)

    Guegel, A.; Becker, M.; Hammel, D.; Mindach, L.; Raeder, J.; Simon, T.; Wagner, M.; Muellen, K.

    1992-01-01

    Five grams of a mixture of C 60 /C 70 can be separated in 24 hours by gel permeation chromatography on polystyrene gel. The mobile phase can be completely recovered, and the method can be scaled up by a simple increase in the inner diameter of the column. (orig.) [de

  13. Fitness-compensatory mutations facilitate the spread of drug ...

    Indian Academy of Sciences (India)

    Charissa C. Naidoo

    2017-08-19

    Aug 19, 2017 ... Cells were seeded at 2×105 cells/mL in 24-well cell culture plates (Porvair). Infection ..... the intermediary metabolism and respiration group, and conserved hypotheticals ... cellular growth in F15/LAM4/KZN strains. Mycobacte- .... drugs and is thought to occur as a result of metabolic shut- down (Gomez and ...

  14. Cerebral Lateralization and General Intelligence: Gender Differences in a Transcranial Doppler Study

    Science.gov (United States)

    Njemanze, P.C.

    2005-01-01

    The present study evaluated cerebral lateralization during Raven's progressive matrices (RPM) paradigm in female and male subjects. Bilateral simultaneous transcranial Doppler (TCD) ultrasound was used to measure mean blood flow velocities (MBFV) in the right and left middle cerebral arteries (MCAs) in 24 (15 females and 9 males) right-handed…

  15. Cooking the books around initial public offerings : A study about the pervasiveness of earnings management and investor protection regulations

    NARCIS (Netherlands)

    J. Seger (Jasper)

    2009-01-01

    textabstractMost prior studies suggest that firms opportunistically increase their earnings around an initial public offering (IPO). With a sample of 512 IPOs in 24 countries worldwide I find that IPO firms that are under suspicion of such behaviour, represent only a small proportion (+/-10%) of the

  16. Download this PDF file

    African Journals Online (AJOL)

    DR. AMIN

    Gadagi” tea preparations,. “sak'',”sada” and “magani”.. LD50 values of each type of the tea were determined. Results of phase. I and phase II of the study showed no mortality was recorded in any of the experimental groups of rats in 24hours ...

  17. Legal Frameworks for Higher Education Governance in Sub-Saharan Africa

    Science.gov (United States)

    Saint, William

    2009-01-01

    This is a preliminary survey of the laws and statutes that determine governance arrangements for higher education systems as well as individual institutions in 24 countries of Sub-Saharan Africa. Following an overview of recent higher education governance trends within Africa, it describes the current range of practice and most common approaches…

  18. A Qualitative Study of Student Responses to Body Painting

    Science.gov (United States)

    Finn, Gabrielle M.; McLachlan, John C.

    2010-01-01

    One hundred and thirty-three preclinical medical students participated in 24 focus groups over the period 2007-2009 at Durham University. Focus groups were conducted to ascertain whether or not medical students found body painting anatomical structures to be an educationally beneficial learning activity. Data were analyzed using a grounded theory…

  19. The anti-tick properties of the root extracts of Senna italica subsp ...

    African Journals Online (AJOL)

    SERVER

    2007-11-15

    Nov 15, 2007 ... extract of S. italica subsp. arachoides in 24 h was 8.66% (w/v) while in 48 h was 3.59% ..... extract of neem seed oil (Azadirachta indica) on egg, immature and ... insecticides on diamondbuck moth (Lepidoptera: Plutellidae).

  20. Experiments on prevention of the endotoxin-abortifacient effect by radiodetoxified endotoxin pretreatment in rats

    Energy Technology Data Exchange (ETDEWEB)

    Csordas, T; Bertok, L; Csapo, Z

    1978-01-01

    Endotoxemia has been induced in pregnant rats by intravenous injection of 1 mg Escherichia coli endotoxin which resulted in intrauterine death and abortion of fetuses in 24 h. The abortifacient effect of endotoxin, injected intravenously 24 h earlier. The authors suppose that the radiodetoxified endotoxin can be a good tool also in the prevention of human septic (endotoxin) shock in pregnancy.

  1. 24 CFR 1003.503 - Program income.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Program income. 1003.503 Section....503 Program income. (a) Program income requirements for ICDBG grantees are set forth in 24 CFR 85.25, as modified by this section. (b) Program income means gross income received by the grantee or a...

  2. Reproducibility of 3.0 Tesla Magnetic Resonance Spectroscopy for Measuring Hepatic Fat Content

    NARCIS (Netherlands)

    van Werven, Jochem R.; Hoogduin, Johannes M.; Nederveen, Aart J.; van Vliet, Andre A.; Wajs, Ewa; Vandenberk, Petra; Stroes, Erik S. G.; Stoker, Jaap

    Purpose: To investigate reproducibility of proton magnetic resonance spectroscopy (H-1-MRS) to measure hepatic triglyceride content (HTGC). Materials and Methods: In 24 subjects, HTGC was evaluated using H-1-MRS at 3.0 Tesla. We studied "between-weeks" reproducibility and reproducibility of H-1-MRS

  3. Litter Quality of Populus Species as Affected by Free-Air CO2

    NARCIS (Netherlands)

    Vermue, E.; Buurman, P.; Hoosbeek, M.R.

    2009-01-01

    The effect of elevated CO2 and nitrogen fertilization on the molecular chemistry of litter of three Populus species and associated soil organic matter (SOM) was investigated by pyrolysis-gas chromatography/mass spectrometry. The results are based on 147 quantified organic compounds in 24 litter

  4. Perceived Mental Illness Stigma among Youth in Psychiatric Outpatient Treatment

    Science.gov (United States)

    Elkington, Katherine S.; Hackler, Dusty; McKinnon, Karen; Borges, Cristiane; Wright, Eric R.; Wainberg, Milton L.

    2012-01-01

    This research explores the experiences of mental illness stigma in 24 youth (58.3% male, 13-24 years, 75% Latino) in psychiatric outpatient treatment. Using Link and Phelan's (2001) model of stigmatization, we conducted thematic analysis of the interview texts, examining experiences of stigma at individual and structural levels, in addition to the…

  5. Block Scheduling: Restructuring the School Day. Hot Topics Series.

    Science.gov (United States)

    Flinders, David J., Ed.

    The advantages and disadvantages of block scheduling are considered in 24 articles. The editors provide an overview for each section and a conclusion for the anthology. The first section includes articles which examine issues, concepts, and cases: (1) "All around the Block" (Michael D. Rettig and Robert Lynn Canady); (2) "Block Scheduling: A Means…

  6. 24 CFR 241.800 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... SUPPLEMENTARY FINANCING FOR INSURED PROJECT MORTGAGES Contract Rights and Obligations-Multifamily Projects Without a HUD-Insured or HUD-Held Mortgage § 241.800 Definitions. All of the definitions contained in... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Definitions. 241.800 Section 241...

  7. Short-Term Auditory Memory in Children Using Cochlear Implants and Its Relevance to Receptive Language.

    Science.gov (United States)

    Dawson, P. W.; Busby, P. A.; McKay, C. M.; Clark, G. M.

    2002-01-01

    A study assessed auditory sequential, short-term memory (SSTM) performance in 24 children (ages 5-11) using cochlear implants (CI). The CI group did not have a sequential memory deficit specific to the auditory modality. Visual spatial memory was the main predictor of variance in the language scores of the CI group. (Contains references.)…

  8. DNA polymorphism of HLA class II genes in systemic lupus erythematosus

    DEFF Research Database (Denmark)

    Cowland, J B; Andersen, V; Halberg, P

    1994-01-01

    We investigated the DNA restriction fragment length polymorphism (RFLP) of the major histocompatibility complex (MHC) genes: HLA-DRB, -DQA, -DQB, -DPB in 24 Danish patients with systemic lupus erythematosus (SLE) and in 102 healthy Danes. A highly significant increase of the frequency of the DR3...

  9. Recto-sigmoid polypectomy by a handmade snare: Experience of 24 ...

    African Journals Online (AJOL)

    A handmade snare is designed from easily available materials to treat bleeding per rectum in children due to rectosigmoid polyps. A total of 29 polypectomies were done in 24 patients. It is simple, effective, safe and economic. Key words: Bleeding per rectum, children, juvenile polyp, snare polypectomy ...

  10. Repair of the meniscus. An experimental investigation in rabbits

    NARCIS (Netherlands)

    Veth, R. P.; den Heeten, G. J.; Jansen, H. W.; Nielsen, H. K.

    1983-01-01

    The healing process of wedge-shaped and longitudinal lesions in the meniscus of the knee was investigated in 74 menisci in 24 Chinchilla rabbits. In four cases the whole meniscus was removed and reimplanted. healing was most evident in the wedge-shaped lesions, which were repaired by fibrocartilage.

  11. Location-level links between diversity and innovative climate depend on national power distance

    NARCIS (Netherlands)

    Van der Vegt, Gerben S.; Van de Vliert, Evert; Huang, X

    2005-01-01

    In this study, we examined the relationship between the demographic diversity and innovative climates of 248 organizational locations of a multinational company in 24 countries. Supporting a status characteristics perspective, multilevel analyses revealed that diversity in the more task-oriented

  12. Gunshot injuries of the spine - a review of 49 cases managed at the ...

    African Journals Online (AJOL)

    The spinal injury was complete in 38 and incomplete in 8, with 3 having no neurological deficit. The level was cervical in 13, thoracic in 24 and lumbar in 12. Only 9 patients improved neurologically. The spine was considered stable in 43 cases. Stabilisation was performed in the 6 unstable cases. The bullets were removed ...

  13. Untitled

    Indian Academy of Sciences (India)

    The Intimate Nature of Muscular Contraction 15 technique (Singh and Singh, 1953). In this technique the dying muscle is allowed to relax passively in distilled water or urea solution. After. *imal relaxation in 24 hours, potassium chloride produces further relaxa- tion. If the muscle is allowed to relax actively in distilled water or ...

  14. Research

    African Journals Online (AJOL)

    2012-10-30

    Oct 30, 2012 ... Prevalence of lipodystrophy and metabolic syndrome among HIV positive ... Use of highly active antiretroviral therapy has led to significant ..... Hypertriglyceridemia were detected in 39%, hypertension in 35.1%, impaired fasting plasma glucose in 24.9%, low HDL .... resistance due to altered fat distribution.

  15. 24 CFR 963.1 - Purpose.

    Science.gov (United States)

    2010-04-01

    ... by this part is based on the established procurement procedures set forth in 24 CFR 85.36, with... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Purpose. 963.1 Section 963.1... HOUSING-CONTRACTING WITH RESIDENT-OWNED BUSINESSES General § 963.1 Purpose. The purpose of this part is to...

  16. A Controlled Study of Effect of Counseling on Psychological ...

    African Journals Online (AJOL)

    ... high in 24 (54.9%) respondents in group 2 who had counseling and were unemployed; depression was associated with occupation (P<0.04). Counseling reduces psychological symptoms in people living with HIV/AIDS. Therefore its use should be encouraged in people living with the disease to boost self-esteem needed ...

  17. Fermentation of sugar beet molasses to alcohol

    Energy Technology Data Exchange (ETDEWEB)

    Sements, P A

    1959-01-01

    Continuously operating equipment is described. The mode of operation is presented. It is possible to prepare 8.5 x 10 to the power of 4 L of ethanol and 12 to 14 long tons of high grade bakers' yeast in 24 hours.

  18. Extracellular β-D-fructofuranosidase from Aspergillus parasiticus ...

    African Journals Online (AJOL)

    LUCCA, A. L.

    2013-09-18

    Sep 18, 2013 ... submerged fermentation was optimized by factorial design and high levels of enzyme were obtained in. 24 h-old cultures at 30°C ... electrophoresis; EDTA, ethylenediaminetetraacetic acid. ... bacteria (Awad et al., 2013), yeast (Kumar and ..... caespitosus under submerged or solid state fermentation using.

  19. 76 FR 31943 - Notice of Proposed Information Collection Requests

    Science.gov (United States)

    2011-06-02

    ..., Evaluation and Policy Development Type of Review: New. Title of Collection: Analysis of State Bullying Laws... bullying laws and policies. The field data collection portion of the study will involve case studies conducted in 24 school sites nationwide to document state and local implementation of anti-bullying laws and...

  20. Præsentation af symptomer i almen praksis hos patienter med cancer

    DEFF Research Database (Denmark)

    Nielsen, Tine Nørgaard; Hansen, Rikke Pilegaard; Vedsted, Peter

    2010-01-01

    and prostate cancer presented diagnosis-specific symptoms (change in bowel habits, cough and bladder dysfunction) as well as more non-specific symptoms (pain, weight loss and fatigue). The GPs interpreted the symptoms as alarm symptoms in 49%, as general symptoms in 24% and as non-cancer specific symptoms...

  1. Decolorization of dyes by recombinase CotA from Escherichia coli ...

    African Journals Online (AJOL)

    The CotA laccase could efficiently decolorize anthraquinone and azo dyes in 24 h. The decolourization capacity of this recombinant laccase suggested that it could be a useful biocatalyst for the treatment of dye-containing effluents. Key words: Recombinant CotA laccase, Escherichia coli, purification, dye decolorization.

  2. HLA-DP antigens in patients with alopecia areata

    DEFF Research Database (Denmark)

    Ødum, Niels; Morling, N; Georgsen, J

    1990-01-01

    The distribution of HLA-DP antigens were studied in 41 patients with alopecia areata (AA) and 188 ethnically matched controls. An increase of DR4 and possibly DR5 in 24 of these patients has previously been reported. HLA-DP typing for DPw1 through w6 and the local specificity, CDP HEI, was perfor...

  3. Cohort study of predictive value of urinary albumin excretion for atherosclerotic vascular disease in patients with insulin dependent diabetes

    DEFF Research Database (Denmark)

    Deckert, T; Yokoyama, H; Mathiesen, E

    1996-01-01

    atherosclerotic vascular disease during follow up of 2457 person year. Elevated urinary albumin excretion was significantly predictive of atherosclerotic vascular disease (hazard ratio 1.06 (95% confidence interval 1.02 to 1.18) per 5 mg increase in 24 hour urinary albumin excretion, P = 0.002). Predictive effect...

  4. Getting logistics closer to end users

    NARCIS (Netherlands)

    Luis, J.G.; Hernández, J.G.; Rodriguez, G.P.; Carcel, G.H.; Hofman, W.

    2014-01-01

    Nowadays, logistics could make you purchase a book in Amazon and delivering it in 24-hours using a service from a logistics operator or a transport company. In a more complex scenario, an order could be traveling around the globe, passing from hand to hand between unknown actors for months. In most

  5. 24 CFR 700.175 - Other Federal requirements.

    Science.gov (United States)

    2010-04-01

    ... requirements described in 24 CFR part 44 (OMB Circular A-128). (b) Conflict of interest. In addition to the conflict of interest requirements in OMB Circular A-87 and 24 CFR part 85, no person who is an employee..., and the implementing regulations at 24 CFR part 108; and (3) Racial and ethnic collection requirements...

  6. Right-Left Approach and Reaching Arm Movements of 4-Month Infants in Free and Constrained Conditions

    Science.gov (United States)

    Morange-Majoux, Francoise; Dellatolas, Georges

    2010-01-01

    Recent theories on the evolution of language (e.g. Corballis, 2009) emphazise the interest of early manifestations of manual laterality and manual specialization in human infants. In the present study, left- and right-hand movements towards a midline object were observed in 24 infants aged 4 months in a constrained condition, in which the hands…

  7. A randomized controlled 27 years follow up of three resin composites in Class II restorations

    DEFF Research Database (Denmark)

    Pallesen, Ulla; van Dijken, Jan WV

    2015-01-01

    .1%), followed by occlusal wear (21.6%) and material fracture (18.9%). Non-acceptable color match was seen in 24 (28.3%) of the restorations (AII 2, CP 16, O 6). Cox regression-analysis showed significant influence of the covariates tooth type, caries risk, and bruxing activity of the participants. Conclusions...

  8. A RATIONAL BASIS FOR THE MEASUREMENT OF FREE PHENYTOIN CONCENTRATION IN CRITICALLY ILL TRAUMA PATIENTS

    NARCIS (Netherlands)

    ZIELMANN, S; MIELCK, F; KAHL, R; KAZMAIER, S; SYDOW, M; KOLK, J; BURCHARDI, H

    Phenytoin binding to serum proteins and factors influencing protein binding were investigated in 38 critically ill trauma patients. In 24% of these patients, the free fraction of phenytoin was less-than-or-equal-to 10%, whereas in 76%, the free phenytoin fraction was increased >10%-up to 24%.

  9. Employee Assistance Programs in Higher Education. Alcohol, Mental Health and Professional Development Programming for Faculty and Staff.

    Science.gov (United States)

    Thoreson, Richard W., Ed.; Hosokawa, Elizabeth P., Ed.

    The promotion of employee assistance programs (EAP) in higher education is considered in 24 chapters, with an emphasis on enhancing resources and the academic environment for faculty and staff. Seven topical areas are addressed: history of EAP; characteristics of higher education; alcoholism and other risks in the academic life-style; EAP models…

  10. Memory retention in wild-type and tau mutant Syrian hamsters

    NARCIS (Netherlands)

    Oklejewicz, M; Van Der Zee, EA; Gerkema, MP; Daan, S

    Rats are known to display a temporary deficit in memory function 6 h after training on a learning task, a phenomenon known as the 'Kamin effect'. Later studies showed that maximal retrieval recurs in 24 h intervals after a single training and implied the role of the circadian clock in the

  11. Differential parietal and temporal contributions to music perception in improvising and score-dependent musicians, an fMRI study

    NARCIS (Netherlands)

    Robert Harris; Bauke M. de Jong

    2015-01-01

    Using fMRI, cerebral activations were studied in 24 classically-trained keyboard performers and 12 musically unskilled control subjects. Two groups of musicians were recruited: improvising (n=12) and score-dependent (non-improvising) musicians (n=12). While listening to both familiar and unfamiliar

  12. 7 CFR 3560.104 - Fair housing.

    Science.gov (United States)

    2010-01-01

    ... DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Borrower Management and Operations Responsibilities § 3560... Housing Marketing Plan. (1) Borrowers with housing projects that have four or more rental units must prepare and maintain an Affirmative Fair Housing Marketing Plan (AFHMP) as defined in 24 CFR part 200...

  13. Relating Child Care during Infancy to Externalizing and Internalizing Behaviors in Toddlerhood: How Specific Features of Child Care Quality Matter Depending on a Child's Gender and Temperament

    Science.gov (United States)

    Lemay, Lise; Bigras, Nathalie; Bouchard, Caroline

    2014-01-01

    This study explored whether the relationships between specific features of child care quality and externalizing and internalizing behaviors in 24-month-old children are moderated by gender and temperament. Questionnaires were used to record children's gender and measure their temperament. Child care quality was observed with the "Échelles…

  14. Effects of Photoactivated Titanium Dioxide Nanopowders and Coating on Planktonic and Biofilm Growth of Pseudomonas aeruginosa

    DEFF Research Database (Denmark)

    Polo, Andrea; Diamanti, Maria Vittoria; Bjarnsholt, Thomas

    2011-01-01

    eradication of P. aeruginosa planktonic cells (initial concentration 10(8) cells/ml) in 24 h compared to a 3-log reduction caused by UV-A light alone. In contrast, neither the photocatalytic treatment with TiO(2) film nor that with TiO(2) nanopowder had any effect on P. aeruginosa biofilms at all...

  15. 24 CFR 202.11 - Title I.

    Science.gov (United States)

    2010-04-01

    ... in 24 CFR 25.5. Civil money penalties may be imposed against Title I lenders and mortgagees pursuant... unacceptable risk to the Department; or (iv) Transfer of a Title I loan to a party that does not have a valid...

  16. A Novel Porcine Model of Septic Shock Induced by Acute Respiratory Distress Syndrome due to Methicillin-resistant Staphylococcus aureus

    Directory of Open Access Journals (Sweden)

    Shuo Wang

    2017-01-01

    Conclusions: In the present study, we developed a novel porcine model of septic shock induced by ARDS due to severe MRSA pneumonia with characteristic hyperdynamic and hypodynamic phases in 24 h, which mimicked the hemodynamic changing of septic shock in human.

  17. ISSN 2073 ISSN 2073-9990 East Cent. East Cent. East Cent. Afr. J ...

    African Journals Online (AJOL)

    DELL

    gender, mean operating time, volume of fluid collection in thyroid bed, ... appears to confer several advantages over the routine drainage method and achieves significant reduction of hospital stay, which led to a reduction in costs for the patients ... than 30 ml in 24 hours following which the patients were discharged.

  18. Oxidative stress and antioxidant status in sportsmen two hours after ...

    African Journals Online (AJOL)

    This study was designed to investigate the serum lipid profile and non-enzymatic antioxidants markers (serum uric acid and albumin) as well as lipid hydroperoxide (a marker of oxidative stress) in 39 sportsmen after 2 h of strenuous training exercise and also in 24 sedentary age-matched males who served as controls ...

  19. Characterization of new microsatellite loci for population genetic studies in the Smooth Cauliflower Coral (Stylophora sp.)

    KAUST Repository

    Banguera-Hinestroza, E.; Saenz-Agudelo, P.; Bayer, T.; Berumen, Michael L.; Voolstra, Christian R.

    2013-01-01

    in 24 individuals from samples belonging to a single population from the central region of the Red Sea. The number of alleles ranged from 3 to 15 alleles per locus, while observed heterozygosity ranged from 0. 292 to 0. 95. Six of these loci showed

  20. Redistribution, Recognition and Representation: Working against Pedagogies of Indifference

    Science.gov (United States)

    Lingard, Bob; Keddie, Amanda

    2013-01-01

    This paper reports on an Australian government-commissioned research study that documented classroom pedagogies in 24 Queensland schools. The research created the model of "productive pedagogies", which conjoined what Nancy Fraser calls a politics of redistribution, recognition and representation. In this model pedagogies are…

  1. The implementation of 'snoezelen' in psychogeriatric care: an evaluation through the eyes of caregivers.

    NARCIS (Netherlands)

    Weert, J.C.M. van; Kerkstra, A.; Dulmen, A.M. van; Bensing, J.M.; Peter, J.G.; Ribbe, M.W.

    2004-01-01

    Many intervention studies lack an investigation of the extent to which the intervention was implemented as intended, which makes outcome measures difficult to interpret. The aim of the present study was to gain insight into the implementation process of snoezelen in 24-h dementia care. The

  2. Improving drug treatment in general practice

    NARCIS (Netherlands)

    Veninga, CCM; Denig, P; Zwaagstra, R; Haaijer-Ruskamp, FM

    In the international Drug Education Project, an educational program involving auditing and feedback in peer groups to improve the treatment of asthma and urinary tract infections (UTI) was developed and tested in primary care. Individualized feedback was provided and discussed in 24 Dutch peer

  3. Bactericidal Activity of Copper Oxide Nanocomposite/Bioglass for in Vitro Clindamycin Release in Implant Infections Due to Staphylococcus aureus

    Directory of Open Access Journals (Sweden)

    Alijanian

    2016-08-01

    Full Text Available Background In recent years, bioactive bioceramics such as bioglass and hydroxyapatite (HA have been introduced as a remarkable development in the field of medicine due to their bio-adaptability, non-toxicity, and persistence, in vivo. They have many potential applications in the repair of bone defects and hence they have attracted significant interest from scholars. Objectives The aim of this study was to synthesize inorganic matrix CuO-based bioglasses and evaluate their antibacterial activity against aerobic bacterial infections in bone implants. Methods Nano-composite samples of silica-based bioactive glass, 60S BG with nano-powder CuO, were synthesized using the sol-gel method and then assessed with regard to their antibacterial properties against Staphylococcus aureus using well diffusion agar. The samples included BG58S (58%SiO2, 36%CaO, 6%P2O5, BG/10CuO (58%SiO2, 26%CaO, 6%P2O5, 10%CuO, and BG/20CuO (48%SiO2, 26%CaO, 6%P2O5, 20%CuO. To evaluate their bioactivity, the prepared samples of BG/20CuO, BG/10CuO, and BG58S were immersed in simulated body fluids (SBF. The surface morphology and structure of the samples before and after immersion in the SBF were characterized using scanning electron microscopy (SEM and Fourier transform infrared (FTIR, respectively. Then, the BG/20CuO and BG/10CuO samples were loaded in clindamycin, an antibiotic widely used in the treatment of osteomyelitis, and their release profiles were studied in phosphate buffer solution. Results It was observed that the growth inhibition zone increased through clindamycin release due to the increasing CuO percentage in the nanocomposite of bioactive glass. The bioactivity of the nanocomposite/bioglass with CuO was superior to that of bioglass alone. In this study, the BG/20CuO sample showed a sustained release of clindamycin, which is sufficient for a drug delivery system. Conclusions Increasing the Cu nanoparticles in bioactive glass samples leads to the release of Cu2

  4. Long term follow up of medical therapy of thyroid cancer

    International Nuclear Information System (INIS)

    Jaffiol, C.; Daures, J.P.; Nsakala, N.; Guerenova, J.; Baldet, L.; Pujol, P.; Vannereau, D.; Bringer, J.

    1995-01-01

    106 patients, 114 W, 27 M, were thyroidectomized for differentiated thyroid cancer (follicular 29.3% - papillary 54.3%) with different stages of gravity (N O: 48.2% - N 1: 32.8% - N 2: 19%). Neck dissection was used in cases of involved nodes. One or several doses of 131 I were given to 126 subjects, 106 patients were treated with L thyroxine (LT4) (mean daily dose: 2.5 μg/kg BW). 23 patients presenting intolerance to LT4 with non suppressed TSH for 13 of them were treated by an association of tiratricol (TRIAC) + LT4. The follow up included a yearly check up involving clinical examination, plasma thyroglobulin (Tg) and thyroid stimulating hormone (TSH) assessment, neck ultrasonography and X ray of the chest. Therapy was stopped for 4 weeks in cases with Tg above its detectable value and a total body scan performed with Tg and TSH controls. The mean duration of follow up was 94.5 ± 67.7 months and extended to more than 5 years for 61% of the patients. We observed 22 relapses of the tumor with 4 deaths. Age less then 45 years, appears as the best factor of prognosis. 2 groups of patients were compared to evaluate the incidence of TSH suppression on the relapse free survival (group 1 n = 30 with a TSH ≤ 0.10 mU/1 and group 2 n = 15 with a TSH always > 1 mU/1 during the follow up). The relapse free survival was shorter in group 2 (p 0.01). Association of TRIAC with LT4 leads to a reduction of the daily dose of LT4 (m 25μg/day) with a significant improvement of TSH suppression and clinical tolerance. In conclusion, TSH suppression improves the prognosis in thyroidectomized patients for differentiated carcinoma. Association of TRIAC with LT4 seems able to approve TSH suppression and therapeutic tolerance. (authors). 40 refs., 5 tabs

  5. Study the Seasonal Variability of Plankton and Forage Fish in the Gulf of Khambhat Using Npzfd Model

    Science.gov (United States)

    Kumar, V.; Kumar, S.

    2016-02-01

    Numerical modelling of marine ecology exploits several assumptions and it is indeed quite challenging to include marine ecological phenomena into a mathematical framework with too many unknown parameters. The governing ordinary differential equations represent the interaction of the biological and chemical processes in a marine environment. The key concern in the development of a numerical models are parameterizations based on output, viz., mathematical modelling of ecological system mainly depends on parameters and its variations. Almost, all constituents of each trophic level of marine food web are depended on phytoplankton, which are mostly influenced by initial slope of P-I curve and nutrient stock in the study domain. Whereas, the earlier plankton dynamic models rarely include a compartment of small fish and as an agent in zooplankton mortality, which is most important for the modelling of higher trophic level of marine species. A compartment of forage fish in the modelling of plankton dynamics has been given more realistic mortality rates of plankton, viz., they feed upon phytoplankton and zooplankton. The inclusion of an additional compartment increases complexity of earlier plankton dynamics model as it introduces additional unknown parameters, which has been specified for performing the numerical simulations.As a case study we applied our analysis to explain the aquatic ecology of Gulf of Khambhat (19o 48' N - 22o20' N, 65o E - 72o40' E), west coast of India, which has rich bio-diversity and a high productive area in the form of plankton and forage fish. It has elevated turbidity and varying geography location, viz., one of the regions among world's ocean with high biological productivity.The model presented in this study is able to bring out the essential features of the observed data; that includes the bimodal oscillations in the observed data, monthly mean chlorophyll-a in the SeaWiFs/MODIS Aqua data and in-situ data of plankton. The additional

  6. ESTUDIO DE LA DIVERSIDAD GENÉTICA DE 20 ACCESIONES DE CACAO (Theobroma cacao L. MEDIANTE AP-PCR DE LA COLECCIÓN DEL CENTRO DEL CACAO DE AROMA TENGUEL EN LA FINCA EXPERIMENTAL LA BUSETA

    Directory of Open Access Journals (Sweden)

    Mercedes Susana Carranza Patiño

    2008-06-01

    Full Text Available El presente estudio consistió en determinar la diversidad genética basada en los marcadores RAPD´s (Random Amplification of Polymorphic DNA de 20 accesiones de cacao (Theobroma cacao L.de la variedad Nacional, con características de productividad, y niveles de resistencia, susceptibilidad y tolerancia a las rincipales enfermedades causadas por hongos como Ceratocistys fimbriata, Moniliophtora roreri y Crinipelis perniciosa. Este germoplasma de cacao se encuentra localizado en el Centro de Cacao de Aroma Tenguel, en la Finca Experimental “La Buseta” propiedad de la Universidad Técnica Estatal de Quevedo. La extracción de ADN se la realizó utilizando el protocolo de Doyle & Doyle (1990 con algunas modificaciones. 14 oligonucleótidos fueron utilizados para la obtención de marcadores RAPD´s, de los cuales 9 amplificaron productos reproducibles OPA-15, OPC-07, OPC-9, OPC-4, OPC-3, OPC-1, OPA-12 OPC-13 y OPA-7. Los productos de amplificación fueron migrados en geles de agarosa al 1.2% a 90 voltios por una hora. Los marcadores moleculares fueron analizados por medio de una matriz de datos binarios para calcular las distancias genéticas. Los nueve cebadores utilizados generaron 67 bandas de las cuales 59 (88% fueron polimórficas. El dendrograma mostró dos grupos A y B, en el grupo A se incluyo dos accesiones, y en el grupo B se encuentran los 18 restantes el cual incluye 2 subgrupos B1 y B2 en el subgrupo B1 se incluye la accesión (L-22-H-40, y en el subgrupo B2 están incluidas las accesiones que poseen características de productividad. El nivel de diversidad más alto se obtuvo con los oligonucleótidos OPC 04 (0.80, OPC 07 (0.82. El cebador OPC 01 (0.37 reportó el nivel más bajo. Las accesiones (L-22-H-40 (O.75, (L-34-H-07 (0.86 y el (L-42-H-60 (0.72 presentaron los niveles de variabilidad más altos, siendo los valores más bajos los mostrados por las accesiones (L-26-H-64 (O.48 y (L-23-H63 (O.47. El valor de la diversidad

  7. Ecologia da polinização da amoreira-preta (Rubus sp (Rosaceae em Timbó-SC, Brasil

    Directory of Open Access Journals (Sweden)

    Leônidas João de Mello Junior

    2011-09-01

    Full Text Available O presente trabalho verificou experimentalmente a ecologia da polinização da amoreira-preta (Rubus sp.. Objetivou-se confirmar a síndrome de polinização de Rubus sp., por meio de análise de seu sistema reprodutivo, quantificação da produção diária de néctar, levantamento da entomofauna que visita as flores da amoreira na área de estudo e análise do seu comportamento polinizador. Os experimentos foram realizados em uma área de cultivo de amoreira-preta, no mês de dezembro de 2005, município de Timbó (SC. Constatou-se que a maior taxa de frutificação (48,3 % ± 3,2 ocorreu via polinização livre, onde os insetos não foram excluídos. Foi verificada a ocorrência de autopolinização, porém com taxa inferior de frutificação (12,2% ± 4,9. A anemofilia não foi constatada na espécie. A avaliação da produção de néctar em Rubus sp. resultou em valores compatíveis com a síndrome de melitofilia. Os visitantes florais coletados e observados sobre as flores de Rubus sp. foram predominantemente abelhas da ordem Hymenoptera (97%, que iniciam, em menor número, a atividade de forrageamento às 8h, com pico de atividade às 12h e declinando até às 16h. As coletas resultaram numa amostragem de 1.360 abelhas, divididas em quatro famílias e 13 espécies. A família com maior riqueza de espécies (N = 7 foi Halictidae e a mais abundante foi Apidae, com 1.288 indivíduos. Em Apidae, houve o predomínio da espécie exótica Apis mellifera, cuja representação na amostra foi de 1.246 indivíduos. Os dados da abundância e as observações naturalísticas do seu comportamento da flor apontaram A. mellifera como o principal polinizador de Rubus sp., mas confirmam que as demais espécies de abelhas também participam na polinização de Rubus sp.

  8. Efeito da amonização sobre a composição, a retenção de nitrogênio e a conservação do bagaço e da ponta de cana-de-açúcar

    Directory of Open Access Journals (Sweden)

    Gesualdi Ana Cristina Ladeira de Souza

    2001-01-01

    Full Text Available Foram estudadas a composição bromatológica e a conservação de subprodutos da cana-de-açúcar tratados com 0, 1, 2 e 4% (N-amônia na matéria seca nas formas de amônia anidra, uréia e sulfato de amônio, em arranjo fatorial e delineamento inteiramente casualizado. Não houve alteração no teor de matéria seca do bagaço, em função das fontes de amônia. As fontes de amônia promoveram decréscimo no teor de fibra em detergente neutro do bagaço, entretanto, só com o sulfato de amônia a ponta apresentou tal comportamento. Houve redução no teor de hemicelulose dos subprodutos tratados com uréia, em função dos níveis de amônia. A amonização com sulfato de amônio reduziu o teor de fibra em detergente ácido, principalmente, da ponta. Houve decréscimo no teor de celulose do bagaço tratado com amônia anidra. Os tratamentos resultaram em aumento no teor de proteína bruta de ambos subprodutos, em função dos níveis de amonia. O sulfato de amônio promoveu redução no teor de nitrogênio insolúvel em detergente ácido e maior retenção de nitrogênio nos dois subprodutos. Na maioria dos tratamentos, os períodos após abertura dos silos não alteraram o teor de nitrogênio total dos subprodutos. Os benefícios promovidos pelos tratamentos persistiram até o 48º dia para o bagaço e até o 24º dia para a ponta.

  9. ACTION OF VITAMIN E ON EXPERIMENTAL SEVERE ACUTE LIVER FAILURE.

    Science.gov (United States)

    Miguel, Fabiano Moraes; Schemitt, Elizângela Gonçalves; Colares, Josieli Raskopf; Hartmann, Renata Minuzzo; Morgan-Martins, Maria Isabel; Marroni, Norma Possa

    2017-01-01

    Severe Acute Liver Failure (ALF) is a life-threatening clinical syndrome characterized by hepatocyte necrosis, loss of hepatic architecture, and impairment of liver functions. One of the main causes of ALF is hepatotoxicity from chemical agents, which damage hepatocytes and result in increase of reactive oxygen species. The vitamin E isoform is the one with the strongest biological antioxidant activity. To evaluate the antioxidant effect of vitamin E in this ALF model. We used 56 rats (mean weight of 300 g) divided into eight groups, four groups assessed at 24 hours and 4 assessed at 48 hours after induction: control group (CO); Vitamin E (Vit. E); Thioacetamide (TAA) and Thioacetamide + Vitamina E (TAA+Vit.E). Rats were submitted to injections of thioacetamide (400 mg/kg i.p.) at baseline and 8 hours later. Vitamin E (100 mg/kg ip) was administered 30 minutes after the second dose of thioacetamide. The 48-hour group rats received two additional doses of vitamin E (24h and 36h). At 24h or 48 hours after the administration of the first dose of TAA, rats were weighed and anesthetized and their blood sampled for evaluation of liver integrity through enzymes aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Liver tissue was sampled for assessment of lipid peroxidation (LPO) by the technique TBARS, antioxidant enzymes SOD, CAT, GPx and GST activity, levels of the NO 2 /NO 3 and histology by H&E in two times. The results were expressed as mean ± standard deviation and statistically analyzed by ANOVA followed by Student-Newman-Keuls, with P E, we observed a reduction in liver enzymes AST (U/L) (101.32±19.45 in 24 hours and 97.85±29.65 in 48 hours) related to the TAA group (469.56± 0.69 in 24 hours and 598.23±55.45 in 48 hours) and ALT (U/L) (76.59±8.56 in 24 hours and 68.47±6.49 in 48 hours) compared to the TAA group (312.21±10.23 in 24 hours and 359.15±17.58 in 48 hours). There was a reduction of LPO (nmol/mg Prot) in the TAA+Vit.E group (0

  10. Flavonoids as fruit and vegetable intake biomarkers

    DEFF Research Database (Denmark)

    Krogholm, Kirstine Suszkiewicz

    calculation of the bivariate correlation coefficients is the common approach when using only one reference method. Back in 2002, a strictly controlled dietary intervention study indicated that the sum of 7 different flavonoid aglycones excreted in 24h urine samples potentially could be used as a biomarker...... and cohort studies. The Ph.D. thesis contains four scientific papers. Paper I provides evidence that the sum of 7 flavonoids in 24h urine respond in a linear and sensitive manner to moderate increases in the intake of fruits and vegetables, and thus consolidates that the flavonoids are a valid biomarker...... of fruit and vegetable intakes. In Paper I, the urinary recovery of the 7 flavonoids in morning spot urine (i.e. all urine voids from midnight including the first morning void) was also found to respond to moderate increases in the intake of fruits and vegetables. However, the association was somewhat...

  11. Autopsy findings in surgical-radiotherapeutically treated bladder carcinoma - conclusions for optimization of radiotherapy

    International Nuclear Information System (INIS)

    Fueller, J.; Kob, D.; Fritzsche, V.

    1989-01-01

    Autopsy findings in patients with bladder carcinoma, treated by combined operation and radiotherapy, revealed tendencies of tumor spread as well as complications and late effects of radiotherapy. In 24.5% of the cases tumor tissue was found within the bladder and in 30.5% within the minor pelvis. Metastases were found in 24.1% in iliac lymph nodes, in 21.3% in abdominal lymph nodes. Liver, lungs, bones, and kidneys are main organs for hematological metastasizing. Little or undifferentiated carcinomas and squamous cell carcinomas showed a greater tendency to metastasize than highly and medium-differentiated ureteral carcinomas. The least radiotherapeutical complications and late effects were found in a fractionation with daily 1.5 Gy and a total dose of 60 Gy. (author)

  12. [Effect of osseointegration in the posterior area by Shenggu pills].

    Science.gov (United States)

    Cuifen, Luo; Guoguang, Peng

    2017-10-01

    This study aimed to investigate the osseointegration condition by measuring the implant stability quotient (ISQ) to study the effect of osseointegration in the posterior area by Shenggu pills. A total of 101 DENTIUM implants were placed in 48 patients. Fifty implants placed in 24 patients were addressed as usual, whereas 51 implants placed in 24 patients were treated with Shenggu pills. ISQ was tested on the day of surgery and consecutively at 4, 8, and 12 weeks. All data were analyzed. The efficacy of the treatment group was no much better than that of control group on the day of surgery and consecutively at 12 weeks with no significant difference (P>0.05). The efficacy of the treatment group was significantly better than that of the control group at 4 and 8 weeks (Ppills could accelerate the implant bone union, improve the implants' ISQ, and ensure the success rate of the operation.

  13. Condiciones pluviométricas en los estados del norte de México

    Directory of Open Access Journals (Sweden)

    Rosalía Vidal Zepeda

    1994-06-01

    Full Text Available A brief analysis on precipitation characteristics was done: in an attempt to improve the rational use of water in the arid lands in the northern part of Mexico annual rainfall distribution, mode of precipitation and rain regimes. The maximum rainfall in 24 hours was evaluated from May to October, as well as the annual, also the monthly average rainny days were calculated. The return periods for different amounts of maximum rainfall in 24 hours was calculated for September. The most frequent weather systems responsible for the high precipitation amounts were studied in the daily cloud satellite images. This paper pretends to be a contribution to the Geography of arid zones, where the knowledge of the climatic elements and controls are important, because of their direct influence in some of the regional development activities.

  14. Radioimmunoassay determination of urinary prostaglandins in patients with progressive systemic sclerosis

    International Nuclear Information System (INIS)

    Ramirez P, P.; Erbessd, M.L.; Mares, G.; Recinos, G.; Graef S, A.; Lavalle, C.

    1985-01-01

    The results of urinary determinations of E-2 prostaglandines by radioimmunoassay (RIA) in 24-hour urine are presented for three groups: progressive systemic sclerotic patients with normotension and with elevated or normal APR, progressive systemic sclerotic patients with hypertension and with normal or low APR, control group of normal subjects. In a recent report of progressive systemic sclerosis in patients we demonstrated changes in the urine concentratrion of APR levels, sodium excretion and in total blood volume. Based on these findings we felt the need to perform quantifications of E-2 prostaglandines (PGE-2) in 24-hour recently taken urine samples stored at 70 0 and measure the sodium amounts excreted in the urine. We concluded that urinary determination of E-2 prostaglandines was the most suitable for our study as it allowed the establishment of relationships between APR, aldosterone and metabolic sodium balance. (author)

  15. Ununited fracture neck of femur treated with closed reduction and internal fixation with cancellous screw and fibular strut graft

    Directory of Open Access Journals (Sweden)

    Singh Daria

    2006-01-01

    Full Text Available Background: Ununited fracture neck of femur in young adults has been tackled in various ways. Methods: Twenty five patients of ununited fracture neck of femur in age group 21-55 years were treated by closed reduction, cancellous screw fixation and fibular strut graft and followed up for 2-6 years. Time gap between injury and operation was 6 weeks to 58 weeks. Five cases were previously fixed with various fixation devices. Results: Osseous union was achieved in 24 cases with average time of 18.16 weeks. Main complication encountered in follow-up was avascular necrosis of femoral head, others were joint stiffness and shortening. Functional end results were good to excellent in 24 cases. Conclusion: Closed reduction with internal fixation by cancellous screw and fibular strut grafting is easy and useful procedure.

  16. Intraerythrocytic 2,3-diphosphoglycerate concentration in hypertensive subjects before and following control by anti hypertensive treatment.

    Science.gov (United States)

    Kasparian, H; Konstantopoulos, K; Tassiopoulos, S; Papadogiannis, D; Karadzas, N; Tassiopoulos, T

    1997-09-01

    We measured the 2,3-diphosphoglycerate inraerythrocytic concentration in 24 normal controls and in 24 hypertensives before and following drug therapy. In hypertensives the 2,3-diphosphoglycerate concentration was higher than that of the controls (14.96 mumol/g Hb vs 13.26 mumol/g Hb respectively); the difference is statistically significant (p levels in the patients studied do not seem to differ statistically from those of the controls. This may be a consequence of lower cardiac output in hypertension which results to a lower tissue perfusion, leading to an increased concentration of deoxygenated haemoglobin in the vein blood. Measurement of 2,3-diphosphoglucerate may prove of value in estimating tissue perfusion in hypertension.

  17. Sonography of gallstones and biliary dilatation without a visible aetiology: The infrequency of obstructing choledocholithiasis

    International Nuclear Information System (INIS)

    Cabrera, O.; Van Sonnenberg, E.; Wittich, G.R.; Leopold, G.R.; Gosink, U.B.; Bowen, J.S.; California Univ., San Diego, La Jolla

    1988-01-01

    This paper describes 50 consecutive patients who sonographically had gallbladder stones and dilated bile ducts, but no visible aetiology for the dilatation. We reviewed these cases to determine the frequency of choledocholithiasis in this setting. Common duct stones caused obstruction in only 36% of these patients. Other aetiologies included strictures due to chronic pancreatitis or prior stone passage in 24% of the patients, and malignant obstruction in 16%. In 24% of the patients, no cause was found for biliary dilatation: common duct stones or obstructing tumours were excluded in the group. Since aetiologies other than stones are likely in a majority of cases, further preoperative workup (CT, percutaneous transhepatic cholangiography, ERCP) or intraoperative cholangiography (if the patient requires urgent cholecystectomy) is indicated. The additional studies should provide a diagnosis, help determine whether or not the common duct should be explored, or avoid unnecessary operation in case of incurable malignancy. (orig.)

  18. Increased nocturnal fat oxidation in young healthy men with low birth weight

    DEFF Research Database (Denmark)

    Brøns, Charlotte; Lilleøre, S K; Jensen, C B

    2013-01-01

    OBJECTIVE: Low birth weight (LBW), a marker of disturbed fetal growth, is associated with adiposity and increased risk of type 2 diabetes (T2D). The aim of the study was to investigate whether LBW is associated with changes in 24-h energy expenditure (EE) and/or substrate utilization rates......, potentially contributing to the development of adiposity and/or T2D compared to matched control subjects. MATERIALS/METHODS: Forty-six young, healthy men were included in the study; 20 with LBW (= 10th percentile) and 26 control subjects with normal birth weight (NBW) (50th-90th percentile). The subjects were...... fed a weight maintenance diet and 24-h energy expenditure (EE), respiratory quotient (RQ), and substrate oxidation were assessed in a respiratory chamber. RESULTS: No differences in 24-h EE, RQ or substrate oxidation were observed between LBW and controls. Interestingly, the LBW group exhibited lower...

  19. Study of highly excited high spin states via the (HI, α) reaction

    International Nuclear Information System (INIS)

    Kubono, S.

    1982-01-01

    Three subjects are discussed in this paper. 1) The mechanism of (HI, α) reactions is briefly studied. 2) Possible excitation of molecular resonance states of 12 C- 12 C in 24 Mg through the 12 C( 16 O, α) 24 Mg reaction were investigated. A precise measurement of the level widths in 24 Mg did not support the previous report that the molecular states seen in 12 C + 12 C scattering had been excited in the transfer reaction 12 C( 16 O, α) 24 Mg. 3) Highly excited states in 28 Si, which have a large parentage of 12 C- 16 O, were also studied via the 12 C( 20 Ne, α) 28 Si reaction. An angular correlation measurement revealed the lowest 8 + and 10 + states at 14.00 and 15.97 MeV, respectively, which were selectively excited in the 12 C( 20 Ne, α) reaction. These results suggest a possible new band in 28 Si. (author)

  20. Evaluation of a new computerized psychometric test battery: Effects of zolpidem and caffeine

    OpenAIRE

    Raveendranadh Pilli; MUR Naidu; Usharani Pingali; J C Shobha

    2013-01-01

    Objective: To evaluate the effects of centrally active drugs using a new indigenously developed automated psychometric test system and compare the results with that obtained using pencil- and paper-based techniques. Materials and Methods: The tests were standardized in 24 healthy participants. Reproducibility of the test procedure was evaluated by performing the tests by a single experimenter on two occasions (interday reproducibility). To evaluate the sensitivity of the tests, the effects of...

  1. The role of allofibroblasts transplantation in cartilaginous tissue regeneration process

    OpenAIRE

    Khadjibaev Аbdukhakim Muminovich; Tilyakov Akbar Buriyevich; Magrupov Bokhodir Asadullaevich; Urazmetova Maisa Dmitriyevna; Ubaydullaev Bobur Sabirovich

    2017-01-01

    Aim of investigation. Ground of embryonal allofibroblasts in the process of cartilaginous tissue regeneration. Material and methods. Investigation is based on the study the results of stimulation cartilaginous tissue regeneration process in the conditions of embryonal allofibroblasts application in 24 experimental sexually mature rabbits in which the model of symphysis pubis rupture with its following recovery have been used. Pieces of cartilaginous tissue have been fixed in 10% neutral forma...

  2. A Surgical Treatment Of

    African Journals Online (AJOL)

    user

    Snoring is the noise produced during sleep as a result of partial upper airways obstruction1. It occurs in all age groups, but in general, 10% of men under the age of 30 years and 60% over 60 years snore1. It is reported in 24% of men and. 14% of women among Italians. OSA is reported in 0.3% of men in the 35 – 65 years ...

  3. 24 CFR 1000.142 - What is the “useful life” during which low-income rental housing and low-income homebuyer housing...

    Science.gov (United States)

    2010-04-01

    ... Activities § 1000.142 What is the “useful life” during which low-income rental housing and low-income... recipient shall describe in its IHP its determination of the useful life of each assisted housing unit in... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What is the âuseful lifeâ during...

  4. Evaluation of the effect of different types and location of pacemaker on cardiac function using radionuclide techniques

    International Nuclear Information System (INIS)

    Shi Rongfang; Liu Xiujie; Guo Xiuzhen

    1993-01-01

    Left ventricular function was measured in 24 patients using radionuclide ventriculography before and after planting different types of pacemakers. The results showed that the heart rate, peak filling rate (PFR) and relative cardiac output (RCO) were significantly increased after planting the pacemaker. However, the effects of AAI and VVI on the synchronism of LV were different. AAI can significantly improve the synchronism and compliance of LV

  5. Effect of joint mobilization on the H Reflex amplitude in people with spasticity

    OpenAIRE

    Pérez Parra, Julio Ernesto; Henao Lema, Claudia Patricia

    2011-01-01

    Objective: To determine the effect of ankle joint mobilization on the H reflex amplitude of thesoleus muscle in people with spasticity. Materials and methods: A quasi-experimental study withcrossover design and simple masking was conducted in 24 randomized subjects to initiate thecontrol or experimental group. Traction and rhythmic oscillation were applied for five minutesto the ankle joint. H wave amplitude changes of Hoffmann reflex (electrical equivalent of themonosynaptic spinal reflex) w...

  6. 24 CFR 3288.3 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Definitions. 3288.3 Section 3288.3... “manufactured home” as defined in 24 CFR 3280.2. Manufactured Housing Consensus Committee or MHCC means the consensus committee established pursuant to section 604(a)(3) of the Act, 42 U.S.C. 5403(a)(3). Party or...

  7. Validation Test Report for the BioCast Optical Forecast Model Version 1.0

    Science.gov (United States)

    2015-04-09

    hour forecast sequence have been established for ten months of continuous daily forecasting sequence trails in the northern Gulf of Mexico and the...beam-c field) is combined with today’s NCOM hourly forecast currents to predict the turbidity distribution (c)1 in 24 hours. The following day’s...proxy for turbidity ) coupled with the currents derived from the NCOM, BioCast enables the currents to advect the turbidity pixel information

  8. International Nuclear Waste Management Fact Book

    International Nuclear Information System (INIS)

    Leigh, I.W.

    1994-05-01

    International Nuclear Waste Management Fact Book has been compiled in an effort to provide current data concerning fuel cycle and waste management facilities, R ampersand D programs, and key personnel in 24 countries, including the US, four multinational agencies and 21 nuclear societies. This publication succeeds the previously issued International Nuclear Fuel Cycle Fact Book (PNL-3594), which appeared annually for 13 years. While the title is different, there are no substantial changes in the content

  9. Cardiology

    OpenAIRE

    Fahey, Tom; Schroeder, Knut

    2004-01-01

    This article describes recent developments in cardiology and cardiovascular disease that are likely to be relevant to primary healthcare professionals and their patients. The following subject areas are covered: Primary prevention: recent developments in pharmacological interventions, drug interactions, and drugs that are likely to cause harm; cardiovascular risk estimation and shared decision making with patients; and new developments in 24-hour ambulatory blood pressure monitoring.Second...

  10. Case series

    African Journals Online (AJOL)

    abp

    7 avr. 2016 ... HTA were complicated by heart disease in 24% of cases and by renal disease in 20% of cases ... of clinical specificity. It is not unusual for HTA to be the only manifestation of the disease. In our study we .... Le syndrome de Cushing reste une cause rare d'HTA, sa prévalence dans des centres spécialisés en ...

  11. Measurement and analysis of quadruple (αγγ) angular correlations for high spin states of 24Mg

    International Nuclear Information System (INIS)

    Wiedenhoever, I.; Wuosmaa, A. H.; Lister, C. J.; Carpenter, M. P.; Janssens, R. V. F.; Amro, H.; Caggiano, J.; Heinz, A.; Kondev, F. G.; Lauritsen, T.; Siem, S.; Sonzogni, A.; Bhattacharyya, P.; Devlin, M.; Sarantites, D. G.; Sobotka, L. G.

    2000-01-01

    The high-lying, α-decaying states in 24 Mg have been studied by measuring the complete decay path of α and γ emissions using five segmented Silicon detectors in conjunction with GAMMASPHERE. The authors analyzed the (αγ) triple angular correlations and, for the first time, (αγγ) quadruple correlations. The data analysis is based on a new Fourier transformation technique. The power of the technique is demonstrated

  12. Bioconversion of sugar beet pulps and by-products

    Energy Technology Data Exchange (ETDEWEB)

    Lescure, J.P.; Bourlet, P.

    A new technology for biogas and energy supply by anaerobic digestion of wet vegetal substrats was studied. It was a two step anaerobic process, each resulting from numerous fermentative reactions. About 88% of the pulp substrat can be converted into gas and a volumic load of 7 kg.m/sup 3/ of dry solids was converted in 24 hours. Many technological problems were encountered with beet trash digestion. It was not tested with high loads, but bioconversion rate was about 75%.

  13. Dietary conjugated linoleic acids affect tissue lipid composition but not de novo lipogenesis in finishing pigs

    OpenAIRE

    Bee , Giuseppe

    2001-01-01

    International audience; Dietary conjugated linoleic acids (CLA) have been reported to profoundly affect lipid metabolism and to act as repartitioning agents. Currently, little is known about their effect on the fatty acid profile of tissue lipids in pigs. In the present study we determined the lipid composition of the backfat inner (BFI) and outer layer (BFO), omental fat (OF) and intramuscular fat (IMF) of the longissimus dorsi muscle in 24 Swiss Large White pigs fed diets supplemented eithe...

  14. Occurrence of heterotrophic and coliform bacteria in liquid hand soaps from bulk refillable dispensers in public facilities.

    Science.gov (United States)

    Chattman, Marisa; Gerba, Sheri L; Maxwell, Charles P

    2011-03-01

    The goal of the study discussed in this article was to determine the occurrence of heterotrophic and coliform bacteria in liquid soap from bulk refillable dispensers, obtained from restrooms in a variety of public facilities. A total of 541 samples was collected from five U.S. cities. Liquid soap from dispensers in public areas was found to contain heterotrophic and coliform bacterial numbers averaging more than 106 CFU/mL in 24.8% of the dispensers.

  15. Use of a combined oxygen and carbon dioxide transcutaneous electrode in the estimation of gas exchange during exercise.

    OpenAIRE

    Sridhar, M K; Carter, R; Moran, F; Banham, S W

    1993-01-01

    BACKGROUND--Accurate and reliable measurement of gas exchange during exercise has traditionally involved arterial cannulation. Non-invasive devices to estimate arterial oxygen (O2) and carbon dioxide (CO2) tensions are now available. A method has been devised and evaluated for measuring gas exchange during exercise with a combined transcutaneous O2 and CO2 electrode. METHODS--Symptom limited exercise tests were carried out in 24 patients reporting effort intolerance and breathlessness. Exerci...

  16. Peri and Postparturient Concentrations of Lipid Lipoprotein Insulin and Glucose in Normal Dairy Cows

    OpenAIRE

    BAŞOĞLU, Abdullah; SEVİNÇ, Mutlu; OK, Mahmut

    1998-01-01

    In order to provide uniqe insight into the metabolic disturbences seen after calving cholesterol, triglycerid, high density lipoprotein, low density lipoprotein, very low density lipoprotein, glucose and insulin levels in serum were studied before calving (group I), in aerly (group II) and late (group III) lactation in 24 normal cows. Serum lipoproteins were separeted into various density classes by repeated ultracentrifugation. The results indicate that there was a rise in glucose, trygl...

  17. Percutaneous drainage treatment of primary liver abscesses

    Energy Technology Data Exchange (ETDEWEB)

    Berger, H.; Pratschke, E.; Berr, F.; Fink, U.

    1989-02-01

    28 primary liver abscesses, including 9 amoebic abscesses, in 24 patients were drained percutaneously. Indication for drainage in amoebic abscesses was imminent rupture and clinical symptoms as pleural effusion, lung atelectasis and pain. 95% of the primary abscesses were cured by percutaneous drainage and systemic antibiotic treatment. There was one recurrence of abscess, which was managed surgically. Reasons for drainage failure were: tumour necrosis and tumour perforation with secondary liver abscess.

  18. Percutaneous drainage treatment of primary liver abscesses

    International Nuclear Information System (INIS)

    Berger, H.; Pratschke, E.; Berr, F.; Fink, U.; Klinikum Grosshadern, Muenchen; Klinikum Grosshadern, Muenchen

    1989-01-01

    28 primary liver abscesses, including 9 amoebic abscesses, in 24 patients were drained percutaneously. Indication for drainage in amoebic abscesses was imminent rupture and clinical symptoms as pleural effusion, lung atelectasis and pain. 95% of the primary abscesses were cured by percutaneous drainage and systemic antibiotic treatment. There was one recurrence of abscess, which was managed surgically. Reasons for drainage failure were: tumour necrosis and tumour perforation with secondary liver abscess. (orig.) [de

  19. Standardization of the method for measurement of plasma estrone by radioimmunoassay; Padronizacao do metodo de dosagem de estrona plasmatica por radioimunoensaio

    Energy Technology Data Exchange (ETDEWEB)

    Vilanova, M.S.V.; Moreira, A.C.; Sala, M.M. de; Sa, M.F.S. de [Sao Paulo Univ., Ribeirao Preto, SP (Brazil). Faculdade de Medicina

    1994-10-01

    The present paper has as objective standardize a radioimmunoassay method for measurement of plasma estrone. Ethyl ether was used for plasma extraction. The sensitivity (Minimal detectable dose) was 3,7 pg/tube; the reproducibility (inter assay error) was 8,6%; the precision (intra assay error) was 4,1%. As a biological control the plasma estrone was ml and in 24 patients with polycystic ovarian syndrome (median = 77,9 pg/ml). (author). 6 refs, 2 figs, 2 tabs.

  20. Standardization of the method for measurement of plasma estrone by radioimmunoassay

    International Nuclear Information System (INIS)

    Vilanova, M.S.V.; Moreira, A.C.; Sala, M.M. de; Sa, M.F.S. de

    1994-01-01

    The present paper has as objective standardize a radioimmunoassay method for measurement of plasma estrone. Ethyl ether was used for plasma extraction. The sensitivity (Minimal detectable dose) was 3,7 pg/tube; the reproducibility (inter assay error) was 8,6%; the precision (intra assay error) was 4,1%. As a biological control the plasma estrone was ml) and in 24 patients with polycystic ovarian syndrome (median = 77,9 pg/ml). (author). 6 refs, 2 figs, 2 tabs

  1. Assessment of discharge after 24 hours following elective ...

    African Journals Online (AJOL)

    Readmission was needed for 41(2.8%), 15(1.1%) from study group and 26(1.8%) from control group. The reason in 24(1,7%) was wound infection, 5(0.3%) DVT, two with endometritis and eight (0.6%) due to non- pregnancy related infection. Although, there is slight increase in rate of readmission due to wound infection and ...

  2. Homeless in America: A Children's Story. Part One.

    Science.gov (United States)

    Homes for the Homeless, Inc., New York, NY.

    In the early part of 1999, the Institute for Children and Poverty surveyed almost 2,000 families with more than 4,000 children in 24 locations to assess the state of homeless children across the United States. This report tells their story. Families account for almost 40% of U.S. homeless people, and in some cities that percentage is even higher.…

  3. Comparing Sexuality Communication Among Offspring of Teen Parents and Adult Parents: a Different Role for Extended Family

    OpenAIRE

    Grossman, Jennifer M.; Tracy, Allison J.; Richer, Amanda M.; Erkut, Sumru

    2015-01-01

    This brief report examined teenagers’ sexuality communication with their parents and extended families. It compared who teens of early parents (those who had children when they were adolescents) and teens of later parents (those who were adults when they had children) talk to about sex. Eighth grade students (N=1281) in 24 schools completed survey items about their communication about sex. Structural equation modeling was used to predict communication profiles, while adjusting for the nesting...

  4. Adrenocortical function and reserve in children treated for acute lymphoblastic leukemia

    International Nuclear Information System (INIS)

    Pawlaczyk, B.; Malecka, E.H.; Krause, W.

    1993-01-01

    Serum cortisol and 17 OHS, 17 KS and DHA levels in 24-hour urine were determined in 30 children (22 girls and boys) 0.5 to 4 years after completion of therapy (radio- and chemotherapy) for acute lymphoblastic leukemia (ALL). Serum cortisol after Syncthen (adrenocortical reserve) was determined in 15 girls and 4 boys. The results show that therapy for ALL depresses glucocorticosteroid synthesis; however, it does not disturb the adrenal reserve or androgenesis. (author)

  5. Autonomic neuropathy in nondiabetic offspring of type 2 diabetic subjects is associated with urinary albumin excretion rate and 24-h ambulatory blood pressure: the Fredericia Study

    DEFF Research Database (Denmark)

    Foss, Anne-Catherine; Vestbo, Else; Frøland, Anders

    2001-01-01

    The aim of this study was to examine the impact of parental type 2 diabetes on the autonomic nervous system and to determine whether autonomic neuropathy is present and associated with changes in 24-h ambulatory blood pressure (AMBP) and urinary albumin excretion rate (UAER) in nondiabetic subjects......, Redmond, WA), and UAER was determined through three overnight urine samples. The subjects with parental type 2 diabetes had significantly lower heart rate variation in all three bedside tests (P

  6. Comparison of Steady State Evaporation Models for Toxic Chemical Spills: Development of a New Evaporation Model

    Science.gov (United States)

    1989-11-29

    for diffusivity based on theory : DVab- 0.002e6 703/2 eS/s(bPM11 t/ ,cm/s (28) ab ab 1) where DV-b a molecular diffusion coefflcient of chemical a In...24 Ugt W m -K (48)S[(/hg) + (1/h)] m- K- where ha is the coefficient of heat conduction through the ground, and hl is the liquid heat transfer

  7. Quasi-molecular states in sd-shell nuclei

    International Nuclear Information System (INIS)

    Kubono, S.; Ikeda, N.; Nomura, T.

    1988-08-01

    Quasi-molecular states near and below the threshold of the molecular configuration in sd-shell nuclei are discussed using recent experimental data with particle-gamma coincidence method and particle-particle coincidence method. Possible quasi-molecular states have been identified in 24 Mg as well as in 28 Si and 32 S. The important role of quasi-molecular states are discussed, specifically for the shape evolution of nuclei as a function of excitation energy and angular momentum. (author)

  8. Bioactive antibiotic levels in the human aorta.

    Science.gov (United States)

    Mutch, D; Richards, G; Brown, R A; Mulder, D S

    1982-12-01

    A new bioassay was used to determine the level of active antibiotic within the aortic wall in 24 patients undergoing elective aortic surgery involving prosthetic grafts. The patients were divided into three groups and received either cefazolin, clindamycin, or cefoxitin intravenously at the induction of general anesthesia. Cefazolin and cefoxitin attained satisfactory tissue levels. Clindamycin did not reach therapeutic levels in the aortic wall. Blood levels did not correlate well with tissue levels.

  9. Beyond interference control impairment in ADHD: Evidence from increased intraindividual variability in the color-stroop test

    OpenAIRE

    BORELLA ERIKA; DE RIBAUPIERRE ANIK; CORNOLDI CESARE; CHICHERIO CHRISTIAN

    2012-01-01

    The present study investigates intraindividual variability (IIV) in the Color Stroop test and in a simple reaction time (SRT) task. Performance level and variability in reaction times (RTs)—quantified with different measures such as individual standard deviation (ISD) and coefficient of variation (ICV) as well as ex Gaussian parameters (mu sigma tau)—were analyzed in 24 children with attention deficit/hyperactivity disorder (ADHD) and 24 typically developing children (TDC). Children with ADHD...

  10. Decreased Volume of the Cerebral Ventricles on CT Images in Gilles de la Tourette’s Syndrome

    Directory of Open Access Journals (Sweden)

    Lisbeth Regeur

    1999-01-01

    Full Text Available The aim of the present study was to estimate the volume of the ventricular system comprising lateral plus third ventricles in patients with Gilles de la Tourette's syndrome on computed tomographic (CT scannings using unbiased stereological principles and to compare that volume with a control group. We found a significantly reduced ventricular volume in 24 patients with Gilles de la Tourette's syndrome (GTS compared with 28 controls.

  11. Do school-level factors influence the educational benefits of digital technology? a critical analysis of teachers’ perceptions

    OpenAIRE

    Perrotta, C

    2013-01-01

    The supposed benefits of teachers’ use of information and communications technology(digital technology) are well reported throughout the academic literature—most ofteninvolving issues of enhanced learning outcomes, increased pupil engagement and moreefficient management and organisation of learning. This paper uses survey data from683 teachers in 24 secondary schools across the UK to analyse the factors influencinghow these benefits are being experienced. In particular, the paper explores the...

  12. Automated measuring systems. Automatisierte Messsysteme

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    Microprocessors have become a regular component of automated measuring systems. Experts offer their experience and basic information in 24 lectures and 10 poster presentations. The focus is on the following: Automated measuring, computer and microprocessor use, sensor technique, actuator technique, communication, interfaces, man-system interaction, distrubance tolerance and availability as well as uses. A discussion meeting is dedicated to the theme complex sensor digital signal, sensor interface and sensor bus.

  13. Growth curves for Laron syndrome.

    OpenAIRE

    Laron, Z; Lilos, P; Klinger, B

    1993-01-01

    Growth curves for children with Laron syndrome were constructed on the basis of repeated measurements made throughout infancy, childhood, and puberty in 24 (10 boys, 14 girls) of the 41 patients with this syndrome investigated in our clinic. Growth retardation was already noted at birth, the birth length ranging from 42 to 46 cm in the 12/20 available measurements. The postnatal growth curves deviated sharply from the normal from infancy on. Both sexes showed no clear pubertal spurt. Girls co...

  14. Prevalence of asthma, rhinitis and eczema among 13–14-year-old schoolchildren in Tochigi, Japan

    OpenAIRE

    Kumiya Sugiyama; Takako Sugiyama; Masao Toda; Tatsuo Yukawa; Sohei Makino; Takeshi Fukuda

    2000-01-01

    To analyze the prevalence and severity of asthma, rhinitis and eczema in children living in different countries, the International Study of Asthma and Allergies in Childhood (ISAAC) was developed. The ISAAC Phase One study evaluated approximately 720 000 children in 56 countries, including Japan. In late 1995 and early 1996, we administered the ISAAC questionnaire to 4466 schoolchildren aged 13–14 years of age in 24 schools in Utsunomiya City and Tochigi City (both in Tochigi Prefecture, Japa...

  15. Serum levels of T3 and T4 among workers of contraceptive pills industry

    International Nuclear Information System (INIS)

    Abbas, E.Z.; Emara, A.; Yassen, Y.Z.; Amr, M.M.; Jaras, M.S.

    1985-01-01

    Serum levels of thyroxine and triiodothyronine were determined in 24 workers engaged in contraceptive pills industry and 20 control subjects. Serum thyroxine in exposed subjects was significantly lower, compared to its level in controls. On the other hand, triiodothyronine was significantly higher in exposed workers. Thus, it is concluded that exposure to the dust of contraceptive drugs, namely estrogen and progesterone, produced disturbances in thyroid gland function and thyroid hormone metabolism. (author)

  16. Do the seasonal forests in northeastern Brazil represent a single floristic unit?

    OpenAIRE

    Rodal,MJN.; Barbosa,MRV.; Thomas,WW.

    2008-01-01

    Floristic analyses (Principal Component Analysis and Analysis of Group Indicators) at the genus level were employed to characterize and compare seasonal forest formations in northeastern Brazil. The presence - absence of 248 genera of woody plants occurring in 24 floristic surveys was correlated with geomorphology and climatic variables. The analyses were consistent and point to the existence of two floristic groups of seasonal forests in the region, one more closely related to the Atlantic C...

  17. Young People, Entrepreneurship And Non Formal Learning

    OpenAIRE

    Pantea, Maria-Carmen; Diroescu, Raluca; Podlasek-Ziegler, Maria

    2016-01-01

    The book was published by SALTO-Youth Participation, a Resource Centre of the European Commission. It looks into the relationship between youth work (non-formal learning) and entrepreneurship. The book explores the theoretical developments in the field, the ethical dilemmas and tensions, and proposes practice-oriented information: illustrative examples, strategies for action and methods of non-formal education. Structured in 24 chapters, the book is an opportunity to open up debates and quest...

  18. Designing with objects object-oriented design patterns explained with stories from Harry Potter

    CERN Document Server

    Kak, Avinash C

    2014-01-01

     All code examples in the book are available for download on a companion site with resources for readers and instructors A refreshing alternative to the rather abstract and dry explanations of the  object-oriented design patterns in much of the existing literature on the subject In 24 chapters, Designing with Objects explains well-known design patterns by relating them to stories from the Harry Potter series

  19. Attitudes of Healthcare Providers towards Providing Contraceptives for Unmarried Adolescents in Ibadan, Nigeria

    OpenAIRE

    Ahanonu, Ezihe Loretta

    2014-01-01

    Objective This study sought to assess the attitude of Healthcare Providers towards providing contraceptives for unmarried adolescents in four Local Government Areas in Ibadan, Nigeria. Materials and methods A cross-sectional descriptive study was conducted among 490 Healthcare Providers in 24 randomly selected healthcare facilities using self-administered, pre-tested questionnaires. Results More than half (57.5%) of the respondents perceived the provision of contraceptives for unmarried adole...

  20. Litter Quality of Populus Species as Affected by Free-Air CO2

    OpenAIRE

    Vermue, E.; Buurman, P.; Hoosbeek, M.R.

    2009-01-01

    The effect of elevated CO2 and nitrogen fertilization on the molecular chemistry of litter of three Populus species and associated soil organic matter (SOM) was investigated by pyrolysis-gas chromatography/mass spectrometry. The results are based on 147 quantified organic compounds in 24 litter samples. Litter of P. euramerica was clearly different from that of P. nigra and P. alba. The latter two had higher contents of proteins, polysaccharides, and cutin/cutan, while the former had higher c...

  1. Fingertip replantation: Technical considerations and outcome analysis of 24 consecutive fingertip replantations

    OpenAIRE

    Venkatramani, H.; Sabapathy, S. Raja

    2011-01-01

    Fingertip amputations are one of the most common injuries faced in an emergency department. Finger tip replantation though technically possible, are not regularly done due to the presumed complexity of the procedure and doubts about the outcome. This article deals with our experience of 24 fingertip replantations in 24 patients done over a period of 8 years since the year 2000. Twenty-one fingertips survived. The most common affected digit in the series was thumb followed by index, middle, an...

  2. Viral etiology and incidence of acute gastroenteritis in young children attending day-care centers

    DEFF Research Database (Denmark)

    Rosenfeldt, Vibeke; Vesikari, Timo; Pang, Xiao-Li

    2005-01-01

    BACKGROUND: The purpose of the study was to investigate the frequency, morbidity and cause of acute gastroenteritis in children attending day-care centers in Denmark. METHODS: Children with acute diarrhea (> or =2 consecutive loose stools in 24 hours, with duration of ... 19 day-care centers, were included. Gastroenteritis viruses, group A rotavirus, sapoviruses, noroviruses and astroviruses were detected with reverse transcription-polymerase chain reaction assays. In addition, stool specimens were cultured for bacterial pathogens. Children who were brought...

  3. Radiotherapy for pediatric brain stem tumors

    International Nuclear Information System (INIS)

    Shcherbenko, O.I.; Parkhomenko, R.A.; Govorina, E.V.; Zelinskaya, N.I.; Ardatova, G.V.; Nechaeva, V.N.

    2000-01-01

    The immediate and short-term results of gamma therapy of brain stem tumors in 24 children were evaluated. All the patients were able to sustain treatment due to adjuvant support with dehydrating and hormonal drugs, and beneficial clinical effect was recorded in 80%. However, magnetic resonance tomography showed no decrease in tumor size. Tumor growth relapsed 3-8 months after radiotherapy. Although total dose ranged 60-72 Gy in 19 patients, there was no clinical evidence of radiation injury [ru

  4. Avaliação de níveis de proteína digestível para girinos de rã-touro

    OpenAIRE

    Pinto, Donovan Filipe Henrique [UNESP

    2014-01-01

    Given the importance of growing tadpoles to get good results in frog farming, this study aimed to determine the digestible protein requirement for bullfrog tadpoles and evaluate the deposition of body nutrients. 9,120 bullfrog tadpoles were used, housed in 24 tanks and fed with isocaloric diets (3,676 kcal DE kg- 1) containing 21, 23, 25, 27, 29 and 31 % digestible protein (DP). We evaluated weight gain, feed intake, protein intake, food conversion, specific growth rate (SGR) and protein effi...

  5. Qualitative evaluation of the enterogastric reflux

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez Garcia, A.; Ortega Bevia, J.M.; Garcia Fernandez, S.; Bonet Padilla, R.; Jimenez Garcia, E.; Rodrigues de Quesada, B. (Hospital Universitario da Faculdade de Medicina, Sevilla (Spain)); Szego, T. (Sao Paulo Univ. (Brazil). Faculdade de Medicina)

    Using Tc/sup 99/ - labeled HIDA, enterogastric reflux was studied in 24 subjects - six asymptomatic individuals and 18 previously submitted to gastric surgery for ulcers, through truncular vagotomy + pyloroplasty, gastrectomy with either BI or BII reconstruction. In the control group there was no evidence of reflux. In the subject group, seven of the 18 patients showed clearly enterogastric reflux. It is concluded that method is readily performed, without morbidity in these series, with a clear picture of the enterogastric reflux.

  6. Phytotechnology Technical and Regulatory Guidance and Decision Trees, Revised

    Science.gov (United States)

    2009-02-01

    Anderson, Guthrie, and Walton 1993 Demeton-8- methyl Duckweed ( Lemna minor ) PE, PD Approximately 10% total transformation (PE and PD) measured in 48...Duckweed ( Lemna minor ) PE, PD Approximately 25% total transformation (PE and PD) measured in 24 hours Gao et al. 1998 Malathion Parrot feather...in 14 days Anderson, Kruger, and Coats 1994 Metolachor Duckweed ( Lemna minor ) PE 25% remaining in the water after 16 days Rice, Anderson, and

  7. Dolomitic vegetation of the Sterkfontein Caves World Heritage Site and its importance in the conservation of Rocky Highveld Grassland

    Directory of Open Access Journals (Sweden)

    F. Siebert

    2005-06-01

    Full Text Available An analysis of the vegetation of the Sterkfontein Caves (i.e. the natural area surrounding the caves is presented. Releves were compiled in 24 stratified random sample plots. A TWINSPAN classification, refined by Braun-Blanquet procedures, revealed six plant communities, also referred to as vegetation units. For each of these vegetation units the species richness was determined. Plant communities of conservation importance were identified and new associations were formally described.

  8. Development and characterization of 16 microsatellite markers for the Louisiana pine snake, Pituophis ruthveni, and two congeners of conservation concern

    Science.gov (United States)

    Matthew A. Kwiatkowski; Christopher M. Somers; Ray G. Poulin; D. Craig Rudolph; Jessica Martino; Tracey D. Tuberville; Cris Hagen; Stacey L. Lance

    2010-01-01

    We isolated and characterized 16 microsatellite loci from the Louisiana pine snake, Pituophis ruthveni. Loci were screened in 24 individuals from locations throughout its distribution in Louisiana and Texas. The number of alleles per locus ranged from 4 to 12, observed heterozygosity ranged from 0.200 to 0.875, and the probability of identity ranged from 0.043 to 0.298...

  9. Construction techniques of the high resolution lead / scintillating fibre electromagnetic calorimeter for the KLOE experiment

    International Nuclear Information System (INIS)

    Anelli, M.; Bisogni, G.; Ceccarelli, A.

    1997-07-01

    The electromagnetic calorimeter of the KLOE experiment is a lead-scintillating fibre sampling device. This calorimeter is arranged as a 'barrel', closed at both ends with an 'end-cap'. The barrel consists in 24 modules defining a cylinder, 4.3 long, with 4 m inner diameter. Each end-cap consists of 32 modules running vertically along the chords of the circle inscribed into the barrel. In this paper the calorimeter construction techniques are described

  10. Qualitative evaluation of the enterogastric reflux

    International Nuclear Information System (INIS)

    Jimenez Garcia, A.; Ortega Bevia, J.M.; Garcia Fernandez, S.; Bonet Padilla, R.; Jimenez Garcia, E.; Rodrigues de Quesada, B.; Szego, T.

    1982-01-01

    Using Tc 99 - labeled HIDA, enterogastric reflux was studied in 24 subjects - six asymptomatic individuals and 18 previously submitted to gastric surgery for ulcers, through truncular vagotomy + pyloroplasty, gastrectomy with either BI or BII reconstruction. In the control group there was no evidence of reflux. In the subject group, seven of the 18 patients showed clearly enterogastric reflux. It is concluded that method is readily performed, without morbility in these series, with a clear picture of the enterogastric reflux. (Author) [pt

  11. Study of Histopathology and Melanogenic Activity in Vitiligo

    Directory of Open Access Journals (Sweden)

    Krishnendra Verma

    1980-01-01

    Full Text Available In 30 cases skin biopsy from vitiliginous areas were studied for dopa reaction and in routine sections with H & E. Dopa reaction was completely absent in 24 cases. Epidermal changes were present in 23 cases, and dermal changes in 27 cases. Epidermal changes were hyperkeratosis, thinning of stratum malpighi, spongiosis and dissolution of the basal cell layer. Dermal changes Were round cell in the upper demis as well as hyalinisation, dema and fragmentation of collagen.

  12. Nuevos registros con notas ecológicas y taxonómicas de esponjas dulceacuícolas (Porifera, Spongillidae) en la cuenca del Duero

    OpenAIRE

    Morales, Javier; Negro, Ana Isabel

    2015-01-01

    This work is a contribution to the knowledge of freshwater sponges (Porifera, Demospongiae, Spongillidae) of the Douro River watershed. Specimens were found in 24 of 32 transects in 16 sampling stations. Distribution and several ecological data were obtained in 25 wadeable river transects (20+/5−) and 7 deep lakes (4+/3−) of six sub-basins of the northern Iberian plateau. Four species (Ephydatia fluviatilis, E. muelleri, Heteromeyenia baileyi and Spongilla lacustris) were recorded throughout ...

  13. [Why? How? What for? We must measure the glomerular filtration].

    Science.gov (United States)

    Treviño-Becerra, Alejandro

    2010-01-01

    The measurement of the glomerular filtration shows the degree of the functional qualities and the proficiency of the renal system. Despite new technologies, at present the best accepted technique for measuring the glomerular filtration in most countries is the clearance of creatinine in 24 hour urine. The clearance of creatinine has the advantage that it is confident, easy to reproduce, without technical limitations and low cost.

  14. First survey of fruit fly (Diptera: Tephritidae) and parasitoid diversity among myrtaceae fruit across the state of Bahia, Brazil

    OpenAIRE

    Silva, Lidia Nogueira; Santos, Mírian Silva; Dutra, Vivian Siqueira; Araujo, Elton Lucio; Costa, Marco Antonio; Silva, Janisete Gomes

    2011-01-01

    The objective of this study was to evaluate the diversity of fruit fly (Diptera: Tephritidae) species that use myrtaceous fruit, particularly guava, as hosts in several localities in the state of Bahia and to determine the infestation rates, pupal viability rates, and fruit fly-parasitoid associations. Sampling of myrtaceous fruit was carried out in 24 municipalities in different regions in the state of Bahia. Four fruit fly species, Anastrepha fraterculus, Anastrepha zenildae, Anastrepha sor...

  15. Electronic-cigarette use by individuals in treatment for substance abuse: A survey of 24 treatment centers in the United States

    OpenAIRE

    Gubner, Noah R.; Andrews, K. Blakely; Mohammad-Zadeh, Ana; Lisha, Nadra E.; Guydish, Joseph

    2016-01-01

    Prevalence and reasons for using electronic cigarettes (e-cigarettes) was examined among patients enrolled in 24 substance abuse treatment centers in the United States (N=1,113). Prevalence of e-cigarette use was assessed for the full sample. Bivariate analyses and multivariate logistic regression were used to identify characteristics associated with e-cigarette use among current cigarette smokers (the majority of e-cigarette users). Overall 55.5% of the sample reported lifetime use of e-ciga...

  16. Construction techniques of the high resolution lead / scintillating fibre electromagnetic calorimeter for the KLOE experiment

    Energy Technology Data Exchange (ETDEWEB)

    Anelli, M; Bisogni, G; Ceccarelli, A [INFN, Laboratori Nazionali di Frascati, Rome (Italy); and others

    1997-07-01

    The electromagnetic calorimeter of the KLOE experiment is a lead-scintillating fibre sampling device. This calorimeter is arranged as a `barrel`, closed at both ends with an `end-cap`. The barrel consists in 24 modules defining a cylinder, 4.3 long, with 4 m inner diameter. Each end-cap consists of 32 modules running vertically along the chords of the circle inscribed into the barrel. In this paper the calorimeter construction techniques are described.

  17. Dual kidney transplantation with organs from extended criteria cadaveric donors.

    LENUS (Irish Health Repository)

    D'Arcy, Frank T

    2009-10-01

    The critical shortage of kidneys available for transplantation has led to alternate strategies to expand the pool. Transplantation of the 2 kidneys into a single recipient using organs suboptimal for single kidney transplantation was suggested. We assessed results in 24 grafts allocated for dual kidney transplantation vs those in a control group of 44 designated for single kidney transplantation. Each group underwent pretransplant biopsy and recipients were age matched.

  18. Grape Polyphenols Increase the Activity of HDL Enzymes in Old and Obese Rats

    Directory of Open Access Journals (Sweden)

    Andriy L. Zagayko

    2013-01-01

    Full Text Available HDL particles are protein-rich particles that act as a vehicle for reverse cholesterol transport from tissues to the liver. The purpose of this study was to investigate age-dependent changes in the functional activity of HDL and the effect of high-energy diet on this index, as well as to correct it under the influence of grape polyphenols from “Enoant” obtained from Vitis vinifera grapes. We observed the age-dependent composition changes in HDL particle. It was shown that total lipids and triacylglycerol (TG levels were higher in 24-month-old animals. In obese rats, HDL total lipids and TG levels were higher in 24-month-old than in the 3-month-old and 12-month-old groups but did not differ from 24-month-old group. The plasma HDL paraoxonase (PON and lecithin:cholesterol acyltransferase (LCAT activity levels were decreased in old-aged rats, and cholesteryl ester transfer protein (CETP activity was higher in old rats. Keeping 12-month-old animals on high-fructose diet completely leveled the age differences in the data that have been measured between 12-month-old and 24-month-old rats. After “Enoant” administration, an increase of HDL PON and LCAT activity levels and a reduction of CETP activity were found in 24-month-old and obese rats.

  19. Downregulation of transient receptor potential M6 channels as a cause of hypermagnesiuric hypomagnesemia in obese type 2 diabetic rats.

    Science.gov (United States)

    Takayanagi, Kaori; Shimizu, Taisuke; Tayama, Yosuke; Ikari, Akira; Anzai, Naohiko; Iwashita, Takatsugu; Asakura, Juko; Hayashi, Keitaro; Mitarai, Tetsuya; Hasegawa, Hajime

    2015-06-15

    We assessed the expression profile of Mg(2+)-transporting molecules in obese diabetic rats as a cause of hypermagnesiuric hypomagnesemia, which is involved in the development of insulin resistance, hypertension, and coronary diseases. Kidneys were obtained from male Otsuka Long-Evans Tokushima fatty (OLETF) and Long-Evans Tokushima Otsuka (LETO) obese diabetic rats at the ages of 16, 24, and 34 wk. Expression profiles were studied by real-time PCR and immunohistochemistry together with measurements of urine Mg(2+) excretion. Urine Mg(2+) excretion was increased in 24-wk-old OLETF rats and hypomagnesemia was apparent in 34-wk-old OLETF rats but not in LETO rats (urine Mg(2+) excretion: 0.16 ± 0.01 μg·min(-1)·g body wt(-1) in 24-wk-old LETO rats and 0.28 ± 0.01 μg·min(-1)·g body wt(-1) in 24-wk-old OLETF rats). Gene expression of transient receptor potential (TRP)M6 was downregulated (85.5 ± 5.6% in 34-wk-old LETO rats and 63.0 ± 3.5% in 34-wk-old OLETF rats) concomitant with Na(+)-Cl(-) cotransporter downregulation, whereas the expression of claudin-16 in tight junctions of the thick ascending limb of Henle was not different. The results of the semiquantitative analysis of immunohistochemistry were consistent with these findings (TRPM6: 0.49 ± 0.04% in 16-wk-old LETO rats, 0.10 ± 0.01% in 16-wk-old OLETF rats, 0.52 ± 0.03% in 24-wk-old LETO rats, 0.10 ± 0.01% in 24-wk-old OLETF rats, 0.48 ± 0.02% in 34-wk-old LETO rats, and 0.12 ± 0.02% in 34-wk-old OLETF rats). Gene expression of fibrosis-related proinflammatory cytokines as well as histological changes showed that the hypermagnesiuria-related molecular changes and tubulointerstitial nephropathy developed independently. TRPM6, located principally in distal convoluted tubules, appears to be a susceptible molecule that causes hypermagnesiuric hypomagnesemia as a tubulointerstitial nephropathy-independent altered tubular function in diabetic nephropathy. Copyright © 2015 the American Physiological

  20. Leadership Practices in Hospital Nursing: A Self of Manager Nurses.

    Science.gov (United States)

    Silva, Vânea Lúcia Dos Santos; Camelo, Silvia Helena Henriques; Soares, Mirelle Inácio; Resck, Zélia Marilda Rodrigues; Chaves, Lucieli Dias Pedreschi; Santos, Fabiana Cristina Dos; Leal, Laura Andrian

    2017-04-03

    To assess the frequency of the leadership practices performed by the manager nurses of hospital institutions and their association with the variables of the socioprofessional profile. Cross-sectional, descriptive, correlational study conducted in four hospitals in a city of the state of São Paulo. A sociodemographic questionnaire and the instrument Leadership Practices Inventory were used. Data collection and analysis were based on an exemplary Leadership Practices Model. Eighty-four manager nurses participated in the study. The mean values of the leadership practices used by the nurses were: enable others to act (50.6); encourage the heart (48.2); model the way (46.7); challenge the process (43.3); and inspire a shared vision (43.1). Data analysis also evidenced a correlation between the practice encourage the heart and the variables time of care and employment relationship. The study evidenced the presence of manager nurses exercising moderate leadership, and promoting teamwork, an environment of trust, and a horizontal vision. However, moderate values also reveal managerial aspects to be improved by the leaders by means of organizational strategies and/or tools aimed at best leadership practices. Avaliar a frequência das práticas de liderança executadas pelos enfermeiros gerentes de instituições hospitalares e sua associação às variáveis do perfil socioprofissional. Estudo transversal, descritivo e correlacional, realizado em quatro hospitaisde um município do interior paulista. Utilizou-se de questionário sociodemográfico e do instrumento Leadership Practices Inventory. A coleta e a análise de dados foram fundamentadas em um Modelo de Práticas para Liderança exemplar. Participaram 84 enfermeiros gerentes. As médias das práticas de liderança utilizadas pelos enfermeiros foram: capacitar os outros a agir (50,6), encorajar o coração (48,2), traçar o caminho (46,7), desafiar o processo (43,3) e inspirar uma visão compartilhada (43,1). Na an

  1. The "oligoanalgesia problem" in the emergency care O "problema oligoanalgesia" no cuidado da emergência

    Directory of Open Access Journals (Sweden)

    Ana Maria Calil

    2007-01-01

    (ECGl = 15, parâmetros hemodinâmicos estáveis e vindos diretamente da cena do evento. RESULTADOS: A dor foi um fenômeno presente em 90% dos casos, sendo as dores de intensidade moderada e forte as mais encontradas. Após um período de três horas, uma significativa parte da população(48% permanecia sem analgesia, mesmo na vigência de dor e o uso de opióides foi baixo. CONCLUSÃO: A dor é um fenômeno comum associada ao trauma com sub-tratamento e sub-avaliação em nosso meio e o uso de opióides para dores reconhecidamente muito intensas ainda é um recurso pouco utilizado no Serviço de Emergência, mesmo em pacientes hemodinamicamente estáveis e com Escala de Coma de Gasglow = 15.

  2. Digestibilidade aparente da energia e nutrientes de coprodutos agroindustriais para tilápia do Nilo Apparent digestibility of the energy and nutrients of agro-industrial by-products for Nile tilapia

    Directory of Open Access Journals (Sweden)

    João Sérgio Oliveira Carvalho

    2010-12-01

    Full Text Available Objetivou-se com este estudo determinar os coeficientes de digestibilidade aparente da matéria seca, proteína bruta e da energia bruta dos coprodutos agroindustriais torta de dendê, farelo de algodão, farelo da vagem de algaroba, farelo da folha de mandioca e farelo de cacau para tilápias do Nilo (Oreochromis niloticus. Foram utilizados 150 peixes revertidos sexualmente, com peso de 40 ± 2,6g, distribuídos em 10 gaiolas de 60L, instaladas em cinco caixas de polietileno (310L e seis incubadoras de 200L adaptadas para ensaio de digestibilidade, em um delineamento inteiramente casualizado com cinco tratamentos e três repetições. A determinação dos coeficientes de digestibilidade aparente foi realizada pelo método indireto, com a utilização 0,10% de óxido crômico (Cr2O3, como indicador. Os coeficientes de digestibilidade aparente da matéria seca, proteína bruta e energia bruta, foram, respectivamente, 56,63; 75,87 e 66,87 para torta de dendê; 48,31; 80,51 e 39,63 para farelo de algodão; 48,69; 51,61 e 30,48 para farelo da vagem de algaroba; 50,22; 49,83 e 29,29 para farelo da folha de mandioca e 43,87; 38,47 e 23,13 para farelo de cacau.This study was carried out aimed to determine the dry matter, crude protein and gross energy apparent digestibility coefficients of agro-industrial by-products palm kernel cake, cotton seed meal, mesquite pods meal, aerial parts of cassava meal and cocoa meal for Nile tilapia (Oreochromis niloticus. One hundred and fifty sexually reverted fishes, with weight of 40 ± 2.6g were spread across to teen net pens of 60L, installed in five polyethylene boxes (310L and six hatchers adapted for the digestibility trial (200L, in an entirely randomized layout with five treatments and three repetitions. The apparent digestibility coefficients determination was performed by the indirect method, using 0.10% chromic oxide (Cr2O3, as marker. Apparent digestibility coefficients of dry matter, crude protein and

  3. Pepsin-Cellulase Digestibility of Pasture Silages: Effects of Pasture Type, Maturity Stage, and Variations in the Enzymatic Method Digestibilidad mediante Pepsina-Celulasa de Ensilajes de Pradera: Efectos del Tipo de Pradera, Estado de Madurez y Variaciones en el Método Enzimático

    Directory of Open Access Journals (Sweden)

    Claudia Barchiesi-Ferrari

    2011-06-01

    Full Text Available Enzymatic in vitro digestibility has been studied as a method to predict energy values of forages for ruminants, although results have been affected by type of forage and methodological details of the technique. This work was performed to evaluate the effects of cellulase concentration (0.75, 1.0 and 6.25 g L-1, incubation time (24 or 48 h and type of final washing of the residue (water or acetone on the in vitro digestibility of the dry matter (DMD, organic matter (OMD and content of digestible organic matter in the DM (D value of silages made at three maturity stages from three types of pastures: a permanent pasture (Dactylis glomerata, Lolium perenne, Bromus catharticus Vahl var. catharticus, Trifolium repens and Holcus lanatus; b Italian ryegrass ley (Lolium multiflorum Lam. cv. Tama; c oats (Avena sativa L. and d mixed pasture (L. perenne-T. repens. Regression equations among cellulase results and in vitro values obtained with rumen fluid were also developed. Higher enzyme concentration, longer incubation time and final washing with acetone, resulted in a significant (P La digestibilidad enzimática in vitro ha sido estudiada para predecir el valor energético de forrajes para rumiantes, aunque el tipo de forraje y los detalles metodológicos han afectado los resultados obtenidos. Este trabajo pretende evaluar los efectos de la concentración de celulasa (0,75; 1,0 y 6,25 g L-1, tiempo de incubación (24 o 48 h y tipo de lavado final (agua o acetona del residuo, sobre la digestibilidad in vitro de la materia seca (DMD, materia orgánica (OMD y el contenido de materia orgánica digestible en la materia seca, o valor D (D value de ensilajes hechos con tres estados de madurez, de diferentes praderas: a pradera permanente (Dactylis glomerata, Lolium perenne, Bromus catharticus Vahl var. catharticus, Trifolium repens y Holcus lanatus; b ballica Italiana (Lolium multiflorum Lam. cv. Tama; c avena (Avena sativa L.; y d pradera mixta (L. perenne

  4. Aproveitamento industrial de marisco na produção de lingüiça Shellfish industrial utilization to produce sausage

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    Eliete da Silva Bispo

    2004-12-01

    Full Text Available Foram estudadas as condições do processamento e a aceitabilidade da lingüiça de vongole (Anomalocardia brasiliana, além de avaliar a estabilidade do produto congelado sob os aspectos químico, físico-químico, microbiológico e sensorial. O produto final obedeceu a seguinte formulação: 48% vongole, 5% proteína texturizada de soja, 15% água, 25% gordura suína, 3% albumina, 2% pré-mistura (sais de cura e NaCl, 1,5% condimentos e 0,5% urucum. O produto congelado ficou armazenado à temperatura de -18ºC durante três meses; periodicamente foi avaliado quanto ao pH, umidade, proteínas, lipídios, NBV, índice de peróxidos, reação de Kreiss, quanto à presença de microrganismos patogênicos e toxigênicos e quanto à aparência, aroma, sabor, textura. Os resultados apontaram que a lingüiça de vongole teve uma boa aceitação, com IA entre 78-87% para todos os atributos avaliados, especialmente em relação ao sabor e textura. As amostras foram avaliadas como sabor ideal de marisco e sabor ideal de condimentos por 66,67% e 73,33% dos provadores, respectivamente. Os resultados com o teste de atitude de intenção de compra mostraram que 46,67% dos consumidores tinham intenção provável ou certa de compra do produto. Os resultados da avaliação microbiológica, físico-química, química e sensorial da lingüiça de vongole, indicaram que o produto manteve-se estável, durante 90 dias de armazenamento a temperatura de -18ºC.It was studied the process and the acceptibility of the vongole (Anomalocardia brasiliana sausage, beyond to evaluate the stability of the frozen product as to chemical, physico-chemical, microbiological and sensory aspects. The vongole sausage had the following formulation: 48% vongole, 5% soy protein, 15% water, 25% swine fat, 3% albumin, 2% blend of cure salts and NaCl, 1.5% flavouring, 0.5% colouring. The final product was stored during three months at -18ºC, and the shelf life study included pH, moisture

  5. Transtornos cognitivos e demências na clínica privada do especialista: estudo piloto de um inquérito de auto-avaliação Cognitive disorders and dementias in the private practice of specialists: pilot study of a self-assessment survey

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    Francisco de Assis Carvalho do Vale

    2004-03-01

    Full Text Available OBJETIVO: Conhecer sobre as características de transtornos cognitivos e demências na clínica privada de especialistas e o preparo desses médicos nessa área. MÉTODO: Nesse estudo piloto, foram entregues questionários de auto-avaliação aos neurologistas do Estado de São Paulo, obtendo-se 196 (22,8% respondentes. RESULTADOS: Muitos neurologistas estão envolvidos, concomitantemente com a clínica privada, com atividade de ensino (61,5% e/ou pesquisa (59,5%. A maioria não teve boa formação em transtornos cognitivos e demências durante graduação (77,3% ou residência/especialização (63,1%, entretanto 60,8% consideram satisfatório seu conhecimento na área e 83,0% declaram seu interesse igual ou maior que por outras. As queixas cognitivas mais freqüentes como razão primária da consulta são perda de memória (73,0% e dificuldade de atenção/concentração (48,0%. As demências mais freqüentes no consultório neurológico são do tipo Alzheimer (54,9% e vascular (23,0%. CONCLUSÃO: Transtornos cognitivos e demências representam uma proporção significativa na clínica privada do neurologista. Embora não tenham recebido boa formação em transtornos cognitivos e demências, os neurologistas respondentes demonstraram grande interesse pela área.OBJECTIVES: To know about the features of cognitive disorders and dementias in the private practice of specialists and these doctor's skills on that area. METHOD: In this pilot study, self-assessment questionnaries were delivered to neurologists of São Paulo State and 196 (22,8% were respondents. RESULTS: Many neurologists are involved, besides the private practice, with teaching (61.5% and/or research (59.5% activities. Most of them assessed as not good the training on cognitive disorders and dementias they had had during both the graduate (77.3% and residence (63.1% courses; nevertheless 60.8% self rated their knowledge on that subject as satisfactory and 83.0% declared their interest

  6. Inseminação artificial intra-uterina em leitoas com sêmen criopreservado com dimetilacetamida e glicerol Intrauterine artificial insemination of gilts using cryopreserved boar semen with dimetilacetamide and glycerol

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    Ivan Bianchi

    2008-10-01

    Full Text Available Este estudo teve por objetivo avaliar o uso da dimetilacetamida (DMA e de glicerol na criopreservação de sêmen suíno sobre as taxas de concepção e fertilização in vivo, utilizando o método de inseminação artificial pós-cervical. Foram sincronizadas 60 leitoas pré-púberes e inseminadas com o uso de sêmen congelado com glicerol 3% (30 fêmeas e DMA 5% (30 fêmeas. O método de inseminação utilizado foi o pós-cervical, com concentração de 1 x 10(9 espermatozóides vivos por dose. Após 36 a 40h da inseminação, as fêmeas foram abatidas, sendo realizada a contagem de corpos hemorrágicos (CH nos ovários. Foi realizada a lavagem dos ovidutos das fêmeas, verificando o número de estruturas recuperadas (oócitos e embriões, calculando-se as taxas de concepção e fertilização. A média de CH nas fêmeas do grupo glicerol 3% não diferiu (P>0,05 daquelas do grupo DMA 5% (10,4 x 10,2, respectivamente. Não houve diferença (P>0,05 nas taxas de recuperação de estruturas entre os grupos glicerol 3% (68,9% e DMA 5% (66,9%. Os resultados obtidos nos grupos glicerol 3% e DMA 5% para as taxas de concepção (73,3 x 76,6% e fertilização (48,6 x 59,4% não apresentaram diferença (P>0,05. Conclui-se que não há diferenças nas taxas de concepção e fertilização in vivo utilizando-se sêmen congelado com o uso de dimetilacetamida ou de glicerol.The objective of this study was to evaluate the use of dimethylacetamide (DMA and glycerol in boar semen cryopreservation on the conception and fertility rates.Sixty pre-pubertal gilts were synchronized and inseminated with semen including either glycerol 3% or DMA 5% as cryoprotectants (n=30 for both groups. Artificial insemination was conducted with the intrauterine method using doses with 1 x 10(9 viable spermatozoa. The gilts were slaughtered 36-40h after the insemination and the hemorrhagic bodies (CH in the ovaries were counted. The oviducts were washed, so oocytes and embryos could

  7. Analysis of land use and occupancy in permanent preservation areas according to the hydrography of Ribeirão Água Fria - Bofete, SP - Brazil Análise do uso e ocupação do solo em áreas de preservação permanente, segundo a hidrografia do Ribeirão Água Fria - Bofete - SP

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    Rafael C. Nardini

    2012-10-01

    '30" de latitude sul com uma área de 15.242,84 ha. O mapa de uso do solo foi elaborado por meio da interpretação diretamente na tela do computador de imagem digital de satélite. Nos dados orbitais, a área de estudo está inserida no quadrante A, da imagem TM/Landsat-5, órbita 220, ponto 76, passagem de 8/09/2007. O Sistema de Informação Geográfica empregado foi o Cartalinx. As áreas de conflito da microbacia foram obtidas a partir do cruzamento entre os mapas de uso do solo e de APPs. Os resultados permitiram concluir que mais da metade da área (51,09% está ocupada por pastagens, reflexo de solos arenosos e de baixa fertilidade. Constatou-se, ainda, que apesar de quase metade da microbacia estar coberta com algum tipo de vegetação (48,78% de mata natural/reflorestamento, possui aproximadamente um terço das áreas de preservação permanente utilizadas inadequadamente por pastagens (88,15%, reflorestamento (10,42% e solo exposto (1,43%, totalizando 343,07 ha de áreas conflitantes em um total de 993,26 ha de APPs.

  8. C4. Pneumonia adquirida na comunidade (PAC: estudo retrospectivo num hospital central

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    A. Oliveira

    2003-11-01

    Full Text Available A PAC é uma importante causa de morbilidade e mortalidade nos doentes hospitalizados. O objectivo deste estudo foi analisar a etiologia, factores de risco, tratamento e mortalidade da PAC no internamento. Procedemos a um estudo retrospectivo de 246 doentes, admitidos no nosso Departamento com o diagnóstico de PAC num período de 24 meses. A média etária foi de 58,9 anos e 61% eram do sexo masculino. Em 48,6% existiam comorbilidades. Na radiografia torácica havia envolvimento multilobar em 17,1%, padrão alveolar em 66,7% e derrame pleural em 18,3%.Os agentes etiológicos foram pesquisados em 195 doentes (75,9% e foram positivos em 57 (29,2%: 11% das hemoculturas (19/173; 30% dos exames culturais de expectoração (48/160 e 10.4% das serologias e antigenúria para Legionella (7/67 foram positivos. Nos doentes com etiologia bacteriana o agente etiológico mais frequente foi S. pneumoniae (47%, seguindo-se os Gram-negativos (26% e H. Influenza (18%.A amoxicilina/clavulanato (82,9% e macrólidos (68,1% foram os antibióticos mais usados. Houve associação de antibióticos em 61,6% dos doentes. A duração média do tratamento foi de 12 dias. Em 93% dos doentes assistiu-se a evolução favorável. A mortalidade foi de 5,1%.Concluimos que o S. pneumoniae continua a ser o agente etiológico mais frequente de PAC. A escolha terapêutica esteve de acordo com as guidelines internacionais e o regime terapêutico mostrou-se adequado tendo a maioria das PAC evolução favorável com baixa mortalidade. : CAP is an important cause of morbidity and mortality in hospitalized patients. The aim of this study was to analyze etiology, risk factors, treatment and mortality of CAP. We conducted a retrospective analysis of clinical data from 246 patients admitted to our Department with CAP diagnosis throughout an 24 month period.The patients were in average age 58,9 years old and 61% were male. In 48,6% significant co-morbidities were found. On chest X-ray there

  9. Controle de larvas de Boophilus microplus por Metarhizium anisopliae em pastagens infestadas artificialmente Control of Boophilus microplus larvae by Metarhizium anisopliae in artificially infested pastures

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    Lúcia Mara de Souza Basso

    2005-06-01

    Full Text Available O objetivo deste trabalho foi avaliar a eficiência do controle exercido por Metarhizium anisopliae na população de Boophilus microplus, em pastagens de Brachiaria brizantha, e do híbrido Tifton 85 (Cynodon spp., artificialmente infestadas com fêmeas ingurgitadas do carrapato. Trinta canteiros com 1 m² de área cada foram distribuídos aleatoriamente. Quinze foram pulverizados com esporos do fungo e quinze controles em cada forrageira, constituindo cinco repetições de cada tratamento, foram infestados com número e peso padronizados de fêmeas ingurgitadas do ácaro. Aplicou-se o fungo, na concentração de 1,8x10(8 conídios mL-1, em três situações: pulverização antes da infestação com o carrapato, após a infestação e posterioriormente à emergência das primeiras larvas nos capins. A ação do fungo foi avaliada no 35º, 38º, 41º, 48º, 55º e 61º dia pós-infestação, por meio da contagem de larvas recuperadas. Obteve-se controle de larvas do ácaro, que, nas avaliações realizadas entre o 35º e o 48º dia pós-infestação, variou entre 87% e 94%. As médias das contagens de estágios larvares do carrapato foram menores em todas as amostragens realizadas no capim-Tifton 85, indicando que houve efeito da pastagem na ação do fungo. A situação de aplicação influencia a atividade do fungo, com melhor resultado nas coletas realizadas entre o 41º e 55º dia após infestação em B. brizantha, e aplicação dos conídios logo após a emergência das primeiras larvas.The objective of this work was to evaluate the efficiency of Metarhizium anisopliae fungus against Boophilus microplus population in Brachiaria brizantha and Tifton 85 (Cynodon pastures, artificially infested with tick engorged females. Thirty plots of 1 m² each were randomly distributed in fifteen treated and fifteen control groups per type of grass, establishing five repetitions for each treatment. Pastures were infested with engorged tick females

  10. Composição em aminoácidos de silagens químicas, biológicas e enzimáticas preparadas com resíduos de sardinha Determination of amino-acid composition of silages prepared from sardine residues

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    Doris Floridalma MORALES-ULLOA

    1997-12-01

    Full Text Available Determinou-se a composição em aminoácidos de silagens químicas, biológicas e enzimáticas elaboradas com resíduos de sardinha. Entre os aminoácidos essenciais a leucina apresentou valores mais altos para todas as silagens, a saber, em g/100g de proteína, 8,31 (química; 8,33 (protease 1 semana; 8,42 (pepsina, e 8,06 (inóculo L. plantarum + melaço 2 semanas, seguida pela lisina 6,46; 6,50 6,45, e 9,01; a fenilalanina com 5,32; 5,35 e 5,25 e 5,18. Destaque especial para o aumento na concentração de valina no decorrer do processo de ensilagem passando de 4,80 g/100g de proteína na matéria-prima para 7,67 na silagem química (3 semanas; 6,26 na silagem com meio inóculo de L.plantarum + melaço (48 horas; 6,27 na silagem protease (1 semana e 6,02 na silagem pepsina (2 semanas. A maior concentração de aminoácidos encontrados foi para o ácido glutâmico, que apresentou teor inicial de 15,20g/100g de proteína e posteriormente 14,02 na silagem química após 1 semana; 14,89 na silagem enzimática com protease (1 semana e 17,09 na silagem biológica com meio inóculo L.plantarum + melaço após 48 horas.The composition and amino-acid concentration of chemical, biological and enzymatic silages prepared from sardine residues, were determined. The essential amino-acid, leucine showed the highest values in all silages (8.31; 8,33 8.42; and 8.06 g/100g protein, followed by lysine (6.46, 6.50, 6.45 and 9,.01 g/100 protein, for chemical silage, protease silage after one week pepsin silage in the L. plantarum after 2 weeks respectively. Phenylalanine showed a value of 5.32g/100g protein in the chemical silages after one week, 5.35g/100g in the protease silage after one week, 5.25g/100g in the pepsin silage after two weeks and 5.18g/100g in the silage inoculated with L. plantarum plus its medium, also after two weeks. The increase in the valine during the silage processing deserves special mention, increasing from 4.80/100g protein in the raw

  11. ¿La experiencia es la única forma de mejorar el discurso público en la ciencia?

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    Pablo del Monte-Luna

    2015-01-01

    Full Text Available Introducción: Cualquier practicante de ciencia está frecuentemente expuesto al discurso público (DP: conferencias, congresos, simposios, seminarios, entrevistas, talleres, etc. Por ello, es imprescindible saber comunicar las ideas con claridad y contundencia en una presentación oral. Usualmente, profesionistas y estudiantes enfrentan estas situaciones utilizando el sentido común, asumiendo que las habilidades para dar una buena presentación oral se adquieren con la práctica. Sin embargo es común ver profesionistas que a pesar de tener años de experiencia en foros de DP, siguen haciendo presentaciones orales muy deficientes. La hipótesis de este trabajo es que la práctica, por sí misma, puede no ser la única forma de adquirir dichas habilidades, sino que es posible mejorar el desempeño en las presentaciones orales mediante la enseñanza de las bases científicas del DP. Método: Tras una presentación oral individual de 10 minutos, se aplicó una prueba de desempeño en el DP (prueba Rapee a un grupo de 15 alumnos de posgrado en ciencias marinas antes y después de tomar un curso de DP. En el curso se enseñó la ciencia que existe detrás del DP, los protocolos del DP en la ciencia y la aplicación de los principios del diseño gráfico en el material de apoyo visual de una presentación oral. Los resultados generales de la prueba Rapee aplicada antes y después del curso se compararon mediante un análisis de diferencias de medias de muestras independientes (p valor de 0.05 y los resultados particulares mediante diagramas de contornos que representan la distribución de las calificaciones en función de las evaluaciones. Resultados: la calificación promedio del grupo en la prueba Rapee antes de que los alumnos tomaran el curso, se situó en un nivel de bajo desempeño (48 puntos de 68. Después de haber cursado la materia, este promedio se incrementó significativamente (de 48 a 57 puntos. La mejoría fue más evidente en las

  12. Envelhecimento acelerado em sementes de azevém com e sem solução salina e saturada Accelerated aging of ryegrass seeds submitted to saturated salt solution

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    Lilian Madruga de Tunes

    2011-01-01

    Full Text Available O presente trabalho teve por objetivo analisar a metodologia do teste de envelhecimento acelerado para avaliação do potencial fisiológico de sementes de azevém, bem como verificar a possibilidade do uso de solução não saturada e saturada de NaCl como opção para controle da absorção de água pelas sementes durante a realização do teste, sem reduzir sua sensibilidade. Foram utilizados quatro lotes de sementes, submetidos aos testes de germinação, emergência de plântulas, índice de velocidade de emergência e envelhecimento acelerado, empregando-se os períodos de exposição de 24, 48, 72 e 96h, com e sem solução salina (NaCl. A utilização de solução não saturada e saturada de NaCl diminui a absorção de água pelas sementes de azevém durante o teste de envelhecimento acelerado, acarretando uma taxa de deterioração menos acentuada e resultados menos drásticos e mais uniformes. A opção 24h com solução não saturada (SNS só conseguiu estratificar os lotes em dois grupos, não devendo ser indicada como promissora. Assim, deve-se usar a opção 48h com solução saturada de NaCl (SSS, que estratificou em três lotes.The objective of the present study was to evaluate the methodology of the accelerated aging test to evaluate the physiological potential of s ryegrass seeds, as well as verify the possibility of the use of unsaturated and saturated solution of NaCl as an option for control of water uptake by seeds during the test without reducing its sensitivity. Four lots of ryegrass seeds were tested for germination, seedling emergence, speed emergence and accelerated aging (periods of 24, 48, 72 and 96h, with or without the use of saturated and saline solution of NaCl. The use of unsaturated and saturated solution of NaCl reduces water absorption by ryegrass seeds during the accelerated aging test, resulting in a rate of deterioration is less pronounced ,less drastic and more uniform results. Option 24h with

  13. Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial.

    Science.gov (United States)

    Martínez-García, Miguel-Angel; Capote, Francisco; Campos-Rodríguez, Francisco; Lloberes, Patricia; Díaz de Atauri, María Josefa; Somoza, María; Masa, Juan F; González, Mónica; Sacristán, Lirios; Barbé, Ferrán; Durán-Cantolla, Joaquín; Aizpuru, Felipe; Mañas, Eva; Barreiro, Bienvenido; Mosteiro, Mar; Cebrián, Juan J; de la Peña, Mónica; García-Río, Francisco; Maimó, Andrés; Zapater, Jordi; Hernández, Concepción; Grau SanMarti, Nuria; Montserrat, Josep María

    2013-12-11

    More than 70% of patients with resistant hypertension have obstructive sleep apnea (OSA). However, there is little evidence about the effect of continuous positive airway pressure (CPAP) treatment on blood pressure in patients with resistant hypertension. To assess the effect of CPAP treatment on blood pressure values and nocturnal blood pressure patterns in patients with resistant hypertension and OSA. Open-label, randomized, multicenter clinical trial of parallel groups with blinded end point design conducted in 24 teaching hospitals in Spain involving 194 patients with resistant hypertension and an apnea-hypopnea index (AHI) of 15 or higher. Data were collected from June 2009 to October 2011. CPAP or no therapy while maintaining usual blood pressure control medication. The primary end point was the change in 24-hour mean blood pressure after 12 weeks. Secondary end points included changes in other blood pressure values and changes in nocturnal blood pressure patterns. Both intention-to-treat (ITT) and per-protocol analyses were performed. A total of 194 patients were randomly assigned to receive CPAP (n = 98) or no CPAP (control; n = 96). The mean AHI was 40.4 (SD, 18.9) and an average of 3.8 antihypertensive drugs were taken per patient. Baseline 24-hour mean blood pressure was 103.4 mm Hg; systolic blood pressure (SBP), 144.2 mm Hg; and diastolic blood pressure (DBP), 83 mm Hg. At baseline, 25.8% of patients displayed a dipper pattern (a decrease of at least 10% in the average nighttime blood pressure compared with the average daytime blood pressure). The percentage of patients using CPAP for 4 or more hours per day was 72.4%. When the changes in blood pressure over the study period were compared between groups by ITT, the CPAP group achieved a greater decrease in 24-hour mean blood pressure (3.1 mm Hg [95% CI, 0.6 to 5.6]; P = .02) and 24-hour DBP (3.2 mm Hg [95% CI, 1.0 to 5.4]; P = .005), but not in 24-hour SBP (3.1 mm Hg [95% CI, -0.6 to 6

  14. Re-evaluation of the fludrocortisone test: duration, NaCl supplementation and cut-off limits for aldosterone.

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    Westerdahl, Christina; Bergenfelz, Anders; Larsson, Johanna; Nerbrand, Christina; Valdemarsson, Stig; Wihl, Anders; Isaksson, Anders

    2009-01-01

    Primary aldosteronism (PA) is the most common form of secondary hypertension. Thus, the aims of this study were: (1) to clarify whether the fludrocortisone suppression test (FST), which confirms autonomous aldosterone secretion, is reliable when carried out during a shorter period of time and (2) to confirm the importance of NaCl supplementation. The cut-off limits already obtained for aldosterone in healthy subjects during the FST were applied in hypertensive patients with a high aldosterone to renin ratio (ARR). The healthy subjects were allocated to three groups. Fludrocortisone was administered 4 times daily over 4 days and sodium chloride was supplemented in 3 different doses. The result was applied in 24 hypertensive patients, in 24 healthy subjects (10 women (23-38 years old) and 14 men (23-58 years old)) and in 24 patients with hypertension and high ARR (16 women (45-74 years old) and 8 men (56-73 years old)). Blood pressure, aldosterone, renin, potassium and sodium were measured. After three days of FST, there was a significant decrease in the serum level of aldosterone in the healthy subjects, regardless of high or low sodium chloride supplementation (p<0.001). The decrease in serum aldosterone was significantly less pronounced in patients with PA than in healthy subjects and hypertensive patients without PA (p<0.001). The 95th percentile of plasma aldosterone at the end of the test was 225 pmol/L. The FST can be shortened to 3 days and a daily 500 mg NaCl supplementation is sufficient. A cut-off value for aldosterone of 225 pmol/L after 4 days with FST is appropriate.

  15. Advanced Coats’ disease treated with intravitreal bevacizumab combined with laser vascular ablation

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    Villegas VM

    2014-05-01

    Full Text Available Victor M Villegas,1 Aaron S Gold,1 Audina M Berrocal,2 Timothy G Murray11Ocular Oncology and Retina, Miami, FL, USA; 2Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USAPurpose: To evaluate the impact of intravitreal bevacizumab combined with laser vascular ablation in the management of advanced Coats’ disease presenting with exudative retinal detachment.Methods: This was a retrospective review of 24 children that presented with exudative retinal detachments associated with advanced Coats’ disease. Mean patient age was 62 months (range 9–160 months. Presenting signs included retinal detachment in 24 children (100%, vascular telangiectasia in 24 children (100%, and retinal ischemia in 24 children (100%. Twenty of 24 children presented with elevated, vascular leakage in the fovea (83%. Two children presented with sub-retinal fibrosis associated with presumed long-standing retinal detachment without evidence of rhegmatogenous retinal detachment. Ten patients exhibited vascular alterations in the periphery of the second eye without clinical evidence of exudation. All 24 children were treated with a large-spot-size diode laser directly to areas of abnormal telangiectatic vasculature. All 24 children received intravitreal bevacizumab injection. Results: All 24 children had resolution of exudative retinal detachment, ablation of vascular telangiectasia, and anatomic improvement of the retina. No child exhibited progressive retinal detachment and no eye required enucleation. No cases of neovascular glaucoma were seen. Fellow eyes with peripheral vascular alterations showed no progression to exudative vasculopathy during the observation period. Intravitreal bevacizumab injection was not associated with endophthalmitis or systemically-observed complications.Conclusion: Repetitive intravitreal bevacizumab combined with laser vascular ablation may be utilized effectively

  16. Heart Rate Variability in Association with Frequent Use of Household Sprays and Scented Products in SAPALDIA

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    Adam, Martin; Schaffner, Emmanuel; Barthélémy, Jean-Claude; Carballo, David; Gaspoz, Jean-Michel; Rochat, Thierry; Schindler, Christian; Schwartz, Joel; Zock, Jan-Paul; Künzli, Nino; Probst-Hensch, Nicole; Team, SAPALDIA

    2012-01-01

    Background: Household cleaning products are associated with adverse respiratory health outcomes, but the cardiovascular health effects are largely unknown. Objective: We determined if long-term use of household sprays and scented products at home was associated with reduced heart rate variability (HRV), a marker of autonomic cardiac dysfunction. Methods: We recorded 24-hr electrocardiograms in a cross-sectional survey of 581 Swiss adults, ≥ 50 years of age, who answered a detailed questionnaire regarding their use of household cleaning products in their homes. The adjusted average percent changes in standard deviation of all normal-to-normal intervals in 24 hr (24-hr SDNN) and total power (TP) were estimated in multiple linear regression in association with frequency [air freshening sprays, and scented products. Results: Decreases in 24-hr SDNN and TP were observed with frequent use of all product types, but the strongest reductions were associated with air freshening sprays. Compared with unexposed participants, we found that using air freshening sprays 4–7 days/week was associated with 11% [95% confidence interval (CI): –20%, –2%] and 29% (95% CI: –46%, –8%) decreases in 24-hr SDNN and TP, respectively. Inverse associations of 24-SDNN and TP with increased use of cleaning sprays, air freshening sprays, and scented products were observed mainly in participants with obstructive lung disease (p < 0.05 for interactions). Conclusions: In predominantly older adult women, long-term frequent use of household spray and scented products was associated with reduced HRV, which suggests an increased risk of cardiovascular health hazards. People with preexisting pulmonary conditions may be more susceptible. PMID:22538298

  17. Benefit Analysis of Implementation of Alternative SO2 Quality Standards on Acute Respiratory Syndrome (ARI Incidence Reduction in Indonesia

    Directory of Open Access Journals (Sweden)

    Muhamad Nizar

    2014-12-01

    Full Text Available Indonesia Quality Standard (QS for ambient SO2 for 1 hour time average i.e. 900 μg/m3(equivalent to 360μg/m3in24 hour time average regulated in the Government Regulation No. 41 of 1999 is the most loose compared to the ambient SO2 standards of other countries in the world including WHO QS guideline. This QS is not expected to guarantee the protection of public health in Indonesia. Therefore more stringent QS alternative for ambient SO2 is required. This research examines benefit values in public health aspect if Indonesia tightens its ambient SO2 QS. Two alternative QS for SO2 are used i.e196 μg/m3(equivalent to 78μg/m3in24 hour time average referring to U.S. EPA and 750μg/m3(equivalent to 360μg/m3in24 hour time average referring to PUSARPEDAL. First step is to map distribution of SO2 ambient concentrations in Indonesia. The result indicates that Provinces of Jakarta and Banten have exceeded both alternative QS while Provinces of Yogyakarta, West Java, Central Java, East Java, Bali, and North Sumatra only exceed the alternative QS of 196μg/m3. From the public health aspect, by attaining to the alternative QS of 750μg/m3, Jakarta and Banten will reduce incidence of ARI by 95% and 98%. By attaining to the alternative QS of 196μg/m3, East Java, Bali and North Sumatra will reduce the incidence of ARI by 59%, 51%, and 5%.

  18. Complement activation and liver impairment in trichloroethylene-sensitized BALB/c mice.

    Science.gov (United States)

    Zhang, Jiaxiang; Zha, Wansheng; Wang, Feng; Jiang, Tao; Xu, Shuhai; Yu, Junfeng; Zhou, Chengfan; Shen, Tong; Wu, Changhao; Zhu, Qixing

    2013-01-01

    Our recent studies have shown that trichloroethylene (TCE) was able to induce multisystem injuries in the form of occupational medicamentosa-like dermatitis, including skin, kidney, and liver damages. However, the role of complement activation in the immune-mediated liver injury is not known. This study examined the role of complement activation in the liver injury in a mouse model of TCE-induced sensitization. Treatment of female BALB/c mice with TCE under specific dosing protocols resulted in skin inflammation and sensitization. Skin edema and erythema occurred in TCE-sensitized groups. Trichloroethylene sensitization produced liver histopathological lesions, increased serum alanine aminotransferase, aspartate transaminase activities, and the relative liver weight. The concentrations of serum complement components C3a-desArg, C5a-desArg, and C5b-9 were significantly increased in 24-hour, 48-hour, and 72-hour sensitization-positive groups treated with TCE and peaked in the 72-hour sensitization-positive group. Depositions of C3a, C5a, and C5b-9 into the liver tissue were also revealed by immunohistochemistry. Immunofluorescence further verified high C5b-9 expression in 24-hour, 48-hour, and 72-hour sensitization-positive groups in response to TCE treatment. Reverse transcription-polymerase chain reaction detected C3 messenger RNA expression in the liver, and this was significantly increased in 24-hour and 48-hour sensitization-positive groups with a transient reduction at 72 hours. These results provide the first experimental evidence that complement activation may play a key role in the generation and progression of immune-mediated hepatic injury by exposure to TCE.

  19. Biology and predatory attributes of a diplogasterid nematode, Fictor composticola Khan et al., 2008

    Directory of Open Access Journals (Sweden)

    Bajaj H. K.

    2015-02-01

    Full Text Available Biology of Fictor composticola has been studied on Aphelenchus avenae in vitro. It reproduces by amphimixis, embryonic development is completed in 24 - 27 h and life cycle in 3 - 4 days. Fusion of sperm and egg pronuclei occurs in the uteri. Pulsation of median oesophageal bulb and pressing of lips against egg shell is seen just prior to hatching but teeth seem to play no role in this process. No moulting occurs inside the egg shell and the first stage juvenile hatches out. Female and male undergo mating upon addition of water in the culture plates and continue to swim in copula for a considerable time. A female lays 1.6 - 4.0 eggs in 24 h while feeding upon A. radicicolus. Predation and reproduction is affected by the temperature and 25 - 35 °C is the optimum range for these phenomena. Process of feeding as recorded with a CCTV attached to a compound microscope is described. F. composticola engulfs small preys; sucks the intestinal contents while holding them or cuts the body wall of large-sized preys and then feeds on prolapsed organs. Two sexes differ in their efficiencies of predation, a female on an average kills 53 A. avenae as compared to 11 by a male in 24 h. F. composticola feeds and reproduces on mycophagous nematodes and juveniles of root- knot, cyst and citrus nematodes but does not prey upon adult nematodes having coarsely annulated cuticle. Cannibalism in this species is also observed. F. composticola and Seinura paratenuicaudata prey upon each other. Biocontrol potential of F. composticola for managing nematode problems in button mushroom and agricultural crops has also been discussed.

  20. Organ damage changes in patients with resistant hypertension randomized to renal denervation or spironolactone: The DENERVHTA (Denervación en Hipertensión Arterial) study.

    Science.gov (United States)

    Oliveras, Anna; Armario, Pedro; Sans, Laia; Clarà, Albert; Vázquez, Susana; Molina, Luis; Pareja, Júlia; de la Sierra, Alejandro; Pascual, Julio

    2018-01-01

    Renal denervation and spironolactone have both been proposed for the treatment of resistant hypertension, but their effects on preclinical target organ damage have not been compared. Twenty-four patients with 24-hour systolic blood pressure ≥140 mm Hg despite receiving three or more full-dose antihypertensive drugs, one a diuretic, were randomized to receive spironolactone or renal denervation. Changes in 24-hour blood pressure, urine albumin excretion, arterial stiffness, carotid intima-media thickness, and left ventricular mass index were evaluated at 6 months. Mean baseline-adjusted difference between the two groups (spironolactone vs renal denervation) at 6 months in 24-hour systolic blood pressure was -17.9 mm Hg (95% confidence interval [CI], -30.9 to -4.9; P = .01). Mean baseline-adjusted change in urine albumin excretion was -87.2 (95% CI, -164.5 to -9.9) and -23.8 (95% CI, -104.5 to 56.9), respectively (P = .028). Mean baseline-adjusted variation of 24-hour pulse pressure was -13.5 (95% CI, -18.8 to -8.2) and -2.1 (95% CI, -7.9 to 3.7), respectively (P = .006). The correlation of change in 24-hour systolic blood pressure with change in log-transformed urine albumin excretion was r = .713 (P < .001). At 6 months there was a reduction in albuminuria in patients with resistant hypertension treated with spironolactone as compared with renal denervation. ©2018 Wiley Periodicals, Inc.

  1. European Society of Veterinary Cardiology screening guidelines for dilated cardiomyopathy in Doberman Pinschers.

    Science.gov (United States)

    Wess, G; Domenech, O; Dukes-McEwan, J; Häggström, J; Gordon, S

    2017-10-01

    Dilated cardiomyopathy (DCM) is the most common cardiac disease in large breed dogs and is inherited in Doberman Pinschers with a high prevalence (58%). The European Society for Veterinary Cardiology convened a task force to formulate screening guidelines for DCM in Dobermans. Screening for occult DCM in Dobermans should start at three years of age and use both Holter monitoring and echocardiography. Yearly screening over the life of the dog is recommended, as a one-time screening is not sufficient to rule out future development of DCM. The preferred echocardiographic method is the measurement of the left ventricular volume by Simpson's method of discs (SMOD). Less than 50 single ventricular premature complexes (VPCs) in 24 h are considered to be normal in Dobermans, although detection of any number of VPCs is cause for concern. Greater than 300 VPCs in 24 h or two subsequent recordings within a year showing between 50 and 300 VPCs in 24 h is considered diagnostic of occult DCM in Dobermans regardless of the concurrent echocardiographic findings. The guidelines also provide recommendations concerning ancillary tests, that are not included in the standard screening protocol, but which may have some utility when recommended tests are not available or financially untenable on an annual basis. These tests include assay of cardiac biomarkers (Troponin I and N-Terminal pro-B-type Natriuretic Peptide) as well as a 5-min resting electrocardiogram (ECG). The current guidelines should help to establish an early diagnosis of DCM in Dobermans. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  2. Randomized sham-controlled trial of renal sympathetic denervation in mild resistant hypertension.

    Science.gov (United States)

    Desch, Steffen; Okon, Thomas; Heinemann, Diana; Kulle, Konrad; Röhnert, Karoline; Sonnabend, Melanie; Petzold, Martin; Müller, Ulrike; Schuler, Gerhard; Eitel, Ingo; Thiele, Holger; Lurz, Philipp

    2015-06-01

    Few data are available with regard to the effectiveness of renal sympathetic denervation in patients with resistant hypertension yet only mildly elevated blood pressure (BP). Patients with resistant hypertension and slightly elevated BP (day-time systolic pressure, 135-149 and diastolic pressure, 90-94 mm Hg on 24-hour ambulatory measurement) were randomized in a 1:1 ratio to renal sympathetic denervation with the Symplicity Flex Catheter (Medtronic) or an invasive sham procedure. The primary efficacy end point was the change in 24-hour systolic BP at 6 months between groups in the intention to treat population. A total of 71 patients underwent randomization. Baseline day-time systolic BP was 144.4±4.8 mm Hg in patients assigned to denervation and 143.0±4.7 mm Hg in patients randomized to the sham procedure. The mean change in 24-hour systolic BP in the intention to treat cohort at 6 months was -7.0 mm Hg (95% confidence interval, -10.8 to -3.2) for patients undergoing denervation and -3.5 mm Hg (95% confidence interval, -6.7 to -0.2) in the sham group (P=0.15). In the per protocol population, the change in 24-hour systolic BP at 6 months was -8.3 mm Hg (95% confidence interval, -11.7 to -5.0) for patients undergoing denervation and -3.5 mm Hg (95% confidence interval, -6.8 to -0.2) in the sham group (P=0.042). In patients with mild resistant hypertension, renal sympathetic denervation failed to show a significant reduction in the primary end point of 24-hour systolic BP at 6 months between groups in the intention to treat analysis. URL: http://www.clinicaltrials.gov. Unique identifier: NCT01656096. © 2015 American Heart Association, Inc.

  3. Transition to an intelligent use of cleaner biomass stoves

    DEFF Research Database (Denmark)

    Luis Teles de Carvalho, Ricardo; Jensen, Ole Michael; Vicent, Estela D.

    2016-01-01

    are relevant issues to save energy and avoid greenhouse gas (CO2e) emissions. This work compares the operating performance of 3 types of biomass stoves used in Europe in their interaction with dwellings. Field studies were conducted in 24 houses in Portugal and Denmark to analyse wood-burning behaviours......In Europe, inappropriate user behaviours in the operation of wood-burning stoves (WBSs) results in substantial energy losses where fireplaces and conventional stoves are major contributors to undue emissions of health damaging fine particulate matter (PM2.5). The design and adoption of cleaner WBSs...

  4. Reactions to dietary tartrazine.

    OpenAIRE

    David, T J

    1987-01-01

    Double blind challenges with tartrazine and benzoic acid were performed in hospital in 24 children whose parents gave a definite history of a purely behavioural immediate adverse reaction to one of these substances. The patients, whose ages ranged from 1.6 to 12.4 years, were on a diet that avoided these items, and in all there was a clear history that any lapse of the diet caused an obvious adverse behavioural reaction within two hours. In no patient was any change in behaviour noted either ...

  5. Evaluation of toxic effects with transition metal ions, EDTA, SBTI and acrylic polymers on Aedes aegypti (L., 1762 (Culicidae and Artemia salina (Artemidae

    Directory of Open Access Journals (Sweden)

    Eduardo José de Arruda

    2011-06-01

    Full Text Available This work aimed to evaluate the toxicity of some insecticides compounds on Aedes aegypti and Artemia salina larvae. Bioassays were carried out to evaluate the toxic effect after of 24 and 72 h using the compounds or associations. The LC10, LC50 and LC90 values were obtained and utilized for toxicity comparations. For Ae. aegypti, LC50 were 32.65 mg L-1 in 24 h for Na2[EDTA-Cu(II] and total mortality in 72 h for SAP-Na2[EDTA-Cu(II].

  6. Acute effect on ambulatory blood pressure from aerobic exercise

    DEFF Research Database (Denmark)

    Lund Rasmussen, Charlotte; Nielsen, Line; Linander Henriksen, Marie

    2018-01-01

    session among female cleaners. METHODS: Twenty-two female cleaners were randomised to a cross-over study with a reference and an aerobic exercise session. Differences in 24-h, work hours, leisure time, and sleep ambulatory blood pressure (ABP) were evaluated using repeated measure 2 × 2 mixed...... of 1.5 mmHg (p = 0.03) were found after the aerobic exercise session. During leisure time, the systolic ABP was lowered by 1.7 mmHg (p = 0.04) and the diastolic ABP was unaltered. During sleep, the systolic and diastolic ABP was unaltered. CONCLUSION: A single aerobic exercise session lowered 24-h...

  7. Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity

    DEFF Research Database (Denmark)

    Rasmussen, M H; Juul, A; Kjems, L L

    1995-01-01

    . This suggests a reversible defect in GH release, rather than a persistent preexisting disorder. It is hypothesized that enhanced bioavailability of IGF-I, acting in concert with elevated proinsulin and insulin levels, may account for the lack of stimulation of 24-hr GH release by the hypocaloric diet in obese...... subjects. We conclude that the increase in 24-h spontaneous GH release and IGFBP-1 levels observed in normal subjects during the last 24 h of a 96-h VLCD is abolished in obese subjects. The lack of short term hypocaloric stimulation of spontaneous GH release may promote the retention of body fat...

  8. Action of matrix metalloproteinases at restricted sites in colon anastomosis repair

    DEFF Research Database (Denmark)

    Ågran, Magnus S.; Levin Andersen, Thomas; Mirastschijski, Ursula

    2006-01-01

    compared with adjacent micro-areas of 3-day-old anastomoses. Only this specific tissue compartment underwent a dramatic and significant increase in collagenolysis, amounting to a loss of 10% of existing collagen molecules in 24 hours, and was abolished by metalloproteinase inhibitors. The tissue....... CONCLUSIONS: The unique finding of this study was that the specific tissue holding the sutures of a colon anastomosis lost the most collagen presumably through induction and activation of multiple MMPs that may explain the beneficial effects of treatment with non-selective MMP antagonists....

  9. Calcifying Odontogenic Cyst with Complex Odontoma: Histological and Immunohistochemical Features

    Directory of Open Access Journals (Sweden)

    Nooshin Mohtasham

    2013-01-01

    Full Text Available The calcifying odontogenic cyst (COC is a rare odontogenic cyst. Only 2% of all odontogenic cysts and tumors are COC. COC associated with odontoma (COCaO reported in 24% of COCs. COCaO presents a greater incidence in female, with a ratio of 2 to 1. The highest incidence of COCaO occurs during the second decade with a mean age of 16 years, most frequently occurring in the maxilla (61.5%. Here, we describe a classic case of COCaO of the maxillary incisor-canine region in 17-year-old girl, and discuss the clinicopathological features and immunohistochemical finding of this tumor.

  10. Calcifying Odontogenic Cyst with Complex Odontoma: Histological and Immunohistochemical Features

    Directory of Open Access Journals (Sweden)

    Mohsen Merati

    2012-09-01

    Full Text Available The calcifying odontogenic cyst (COC is a rare odontogenic cyst. Only 2% of all odontogenic cysts and tumors are COC. COC associated with odontoma (COCaO reported in 24% of COCs. COCaO presents a greater incidence in female, with a ratio of 2 to 1. The highest incidence of COCaO occurs during the second decade with a mean age of 16 years, most frequently occurring in the maxilla (61.5%. Here, we describe a classic case of COCaO of the maxillary incisor-canine region in 17-year-old girl, and discuss the clinicopathological features and immunohistochemical finding of this tumor.

  11. Acute renal failure from inhalation of mycotoxins.

    Science.gov (United States)

    Di Paolo, N; Guarnieri, A; Loi, F; Sacchi, G; Mangiarotti, A M; Di Paolo, M

    1993-01-01

    Mysterious deaths of archeologists after opening Egyptian tombs have been suspected to be secondary to inhalation of mycotoxin, however, the hypothesis has never been verified. Recently, we observed a case of acute renal failure (ARF) undeniably due to inhalation of ochratoxin of Aspergillus ochraceus. After spending 8 h in a granary which had been closed for several months, a farmer and his wife suffered temporary respiratory distress; 24 h later, the woman developed nonoliguric ARF and biopsy revealed tubulonecrosis which healed in 24 days. Toxic substances were not found, but a strain of A. ochraceus producing ochratoxin was isolated from the wheat.

  12. Quantitative measurement of cyanide complexes in simulated and actual Hanford ferrocyanide wastes

    International Nuclear Information System (INIS)

    Bryan, S.A.; Pool, K.H.; Sell, R.L.; Bryan, S.L.

    1994-01-01

    Cyanide-containing radioactive waste from radiocesium scavenging processes conducted during the 1950's at Hanford is currently stored in 24 single shell tanks. As part of ongoing tank characterization efforts, the quantity and chemical form of cyanide in these tanks need to be determined. This report summarizes the results of studies conducted at Pacific Northwest Laboratory (PNL) under contract to Westinghouse Hanford Company (WHC) to develop methods for the quantification of total cyanide and identification of major cyanide-containing species in Ferrocyanide Tank Waste. Results from the application of FTIR, IC, and microdistillation procedures to simulated and actual Hanford waste are presented and compared where applicable

  13. Application of inverse kinematics to 1H+23Na→12C+12C

    International Nuclear Information System (INIS)

    Bennett, S.J.; Clarke, N.M.; Freer, M.; Fulton, B.R.; Hall, S.J.; Karban, O.; Murgatroyd, J.T.; Tungate, G.; Gyapong, G.J.; Jarvis, N.S.; Watson, D.L.; Rae, W.D.M.; Smith, A.E.; Lilley, J.S.; Woods, P.J.; Page, R.D.

    1993-01-01

    Some experimental techniques used in the measurement and analysis of inverse kinematic reactions are described and applied to a kinematically complete study of the 1 H( 23 Na, 12 C) 12 C reaction at an incident energy of 180 MeV. An excitation function is obtained for the energy range of 18.5 to 19.2 MeV in 24 Mg*; equivalent to proton energies from 7.1 MeV to 7.8 MeV for the 23 Na(p, 12 C) 12 C reaction. (orig.)

  14. A new process for the fractionation of uranium; Un nuevo procedimiento para el fraccionamiento de uranio

    Energy Technology Data Exchange (ETDEWEB)

    Costas, E.; Baselga, B.; Tarin, F.

    2015-07-01

    We propose a new biological process for uranium isotopic fractionation based on Chlamydomonas cf. fonticola (microalgae) isolated from a pond extremely contaminated by uranium (. 25 ppm) from the ENUSA mine in Saelices (Salamanca, Spain) and genetically improved. The metabolic activity of this genetically improved ChlSPGI strain allows recover 115 mg of U per gram of micoralgal biomass in a short time (because this strain complete their cell cycle in . 24 hours). During this process ChlSPGI microalgae selectively captures {sup 2}35U conducting an isotopic enrichment of {sup 2}35U ({sup 2}35U δ = + 3,983%). (Author)

  15. Mycoplasmas and Non-gonococcal Urethritis

    Directory of Open Access Journals (Sweden)

    Bhushan Kumar

    1989-01-01

    Full Text Available A total of 692 heterosexual males which included 130 men with non-gonoccal urethritis (NGU and 562 age-matched controls, were studied. Mycoplasmas were cultivated in liquid PPLO medium tubes containing arionine and urea. Mycoplasmas were isolated in 24 (18.59o of the 130 patients and 76 (13.60/o of the 562 controls. Ureaplasma urealyticum was isolated in 18 (13.9% gatients with NGU and in 21 (3.8% controls. Mycoplasma hominiq was isolated in 6 (4.6% patientuft NGU and in 55 (9.8% controls. Ureaplasma urealyticurm has a definite in NGU.

  16. Cytotoxicity of nano-hydroxyapatite on human-derived oral epithelium cell line: an in vitro study

    Directory of Open Access Journals (Sweden)

    Farid Abassi

    2016-08-01

    Full Text Available Background: Hydroxyapatite nanoparticles have a more surface contact and solubility than conventional hydroxyapatite. Hydroxynanoparticles enhances the biological and mechanical properties of new regenerated tissues. The hydroxyapatite nanoparticles have received attention as a new and effective osseous graft for using as scaffolds in bone regeneration. The reports on hydroxyapatite nanoparticles biocompatibility are controversial. It has been shown that hydroxyapatite nanoparticles induces inflammatory reaction and apoptosis. The aim of the present study was to evaluate the cytotoxicity of nano-hydroxyapatite on the human epithelial cells. Methods: The study was experimental and completed in vitro. The study was carried out in department of Immonulogy, Faculty of Medicine, Shahid Beheshti University of Medical Sciences in November 2014. The human-derived oral epithelium cell line (KB obtained from Pasteur Institute, Tehran, Iran were exposed to hydroxyapatite nanoparticles at 0.01, 0.05, 0.1, 0.5, 0.75, 1, 2.5 and 5 mg/ml concentrations in 24, 48 and 72 hours. Rod-shaped hydroxyapatite nanoparticles with 99% purity and maximum 100 nm sized particles were used. Methylthiazol tetrazolium bromide (MTT method was employed for cell vitality evaluation. Enzyme-linked immunosorbent assay (ELISA was used for assessing the viability of cells. Distilled water and fetal bovine serum (FBS were positive and negative controls. ANOVA and Duncan tests were used for statistical analysis. Results: The cytotoxicity of different concentrations of hydroxyapatite nanoparticles on human-derived oral epithelium cell line in 24 (P< 0.001, 48 (P< 0.001 and 72 hours (P< 0.001 was significantly different. The nano-hydroxyapatite particles at 0.5 to 1 mg/ml had the highest cytotoxicity effect on human-derived oral epithelium cells in 24, 48 and 72 hours. Lower concentrations than 0.05 mg/ml had the best biocompatibility properties in 24, 48 and 72 hours. Conclusion

  17. Ecological effects of full and partial protection in the crowded Mediterranean Sea: a regional meta-analysis

    DEFF Research Database (Denmark)

    Giakoumi, Sylvaine; Scianna, Claudia; Plass-Johnson, Jeremiah Grahm

    2017-01-01

    the relationships between the level of protection and MPA size, age, and enforcement. Results revealed significant positive effects of protection for fisheries target species and negative effects for urchins as their predators benefited from protection. Full protection provided stronger effects than partial...... to inform decisions. In the human-dominated Mediterranean Sea, fully protected areas occupy only 0.04% of its surface. We evaluated the impacts of full and partial protection on biomass and density of fish assemblages, some commercially important fishes, and sea urchins in 24 Mediterranean MPAs. We explored...

  18. Valoración radiológica del pie zambo congénito idiopático y su correlación clínica en la operación de Codivilla

    OpenAIRE

    Villas, C. (Carlos); Beguiristain, J. (José); Martinez, E. (E.); Barrecheguren, G. (G.)

    2003-01-01

    Thirty-seven patients (52 idiopathic clubfeet) were treated with Codivilla's technique between 1971 and 1985. Radiological measurements and clinical evaluation before and after surgery were performed; a correlation was carried out between these evaluations and personal satisfaction. The results were rated as follows: poor in 4 feet (7.7%), fair in 18 feet (34.6%), good in 24 feet (46.2%) and excellent in 6 feet (11.5%) with a total percentage of satisfactory results amounting to 57.7%. Our co...

  19. [Ankle arthroscopy in clinical application: a preliminary report].

    Science.gov (United States)

    Xu, J S

    1989-01-01

    The results of arthroscopy or arthroscopic synovectomy on 31 ankle joints in 24 cases were reported. All the patients were followed for 2 to 10 months with an average of 6 months. The results were as follows of the 26 rheumatoid arthritis: excellent in 5 ankles (19.2%), good in 8 (30.8%), fair in 7 (26.9%), and poor in 6 (23.6%), of the three traumatic arthritis: good in one and fair in two; of the remaining 2: good in 1 tuberculous synovitis and fair in 1 chronic pyogenic arthritis. The operative procedure, indications and value of ankle arthroscopy together with its advantages were discussed in detail.

  20. Preliminary findings indicate nosocomial transmission and Roma population as most affected group in ongoing measles B3 genotype outbreak in Bulgaria, March to August 2017.

    Science.gov (United States)

    Kurchatova, Anna; Krumova, Stefka; Vladimirova, Nadezhda; Nikolaeva-Glomb, Lubomira; Stoyanova, Asya; Kantardjiev, Todor; Gatcheva, Nina

    2017-09-07

    From March to August 2017, 165 measles cases were reported from three regions in Bulgaria. The age range was 0-55 years and 66% of the cases were under 9 years. The Roma population was disproportionally affected (89% of cases), 41% cases were unvaccinated and in 24 cases there was nosocomial transmission mostly in paediatric departments. A child under 12 months of age died. Control measures have been taken and the investigation is still ongoing. This article is copyright of The Authors, 2017.

  1. Studies on 14C labelled chlorpyrifos in model marine ecosystem

    International Nuclear Information System (INIS)

    Pandit, G.G.; Mohan Rao, A.M.; Kale, S.P.; Murthy, N.B.K.; Raghu, K.

    1997-01-01

    Chlorpyrifos is one of the widely used organophosphorus insecticides in tropical countries. Experiments were conducted with 14 C labelled chlorpyrifos to study the distribution of this compound in model marine ecosystem. Less than 50 per cent of the applied activity remained in water in 24 h. Major portion of the applied chlorpyrifos (about 4.2 % residue per g) accumulated into the clams with sediment containing a maximum of 5 to 6 per cent of applied compound. No degradation of chlorpyrifos was observed in water or sediment samples. However, metabolic products were formed in clams. (author). 4 refs., 3 tabs

  2. Review of Recommender Systems Algorithms Utilized in Social Networks based e-Learning Systems & Neutrosophic System

    Directory of Open Access Journals (Sweden)

    A. A. Salama

    2015-03-01

    Full Text Available In this paper, we present a review of different recommender system algorithms that are utilized in social networks based e-Learning systems. Future research will include our proposed our e-Learning system that utilizes Recommender System and Social Network. Since the world is full of indeterminacy, the neutrosophics found their place into contemporary research. The fundamental concepts of neutrosophic set, introduced by Smarandache in [21, 22, 23] and Salama et al. in [24-66].The purpose of this paper is to utilize a neutrosophic set to analyze social networks data conducted through learning activities.

  3. [Intelligence and creativity changes induced by pathological growth of space-occupying cerebral lesion].

    Science.gov (United States)

    Perfil'ev, A M; Razumnikova, O M; Stupak, V V

    2013-01-01

    Creativity and intelligence changes depending on tumor localization in frontal or parietal cortex before surgical procedure in 24 patients in comparison with control group are studied. Brain damage-induced intelligence impairment and a decrease of fluency, flexibility of figural divergent thinking, and originality of verbal one without specificity of tumor localization were found. Intelligence decrease was more presented while performing of figural tasks and least of all in verbal ones. The left prefrontal brain damage induced a decrease of all components of intelligence and a trend to a decrease of verbal creativity and figural fluency. The right parietal brain lesion was more associated with a decline of divergent thinking originality.

  4. Effects of oral contraceptives on thyroid tests using 131I

    International Nuclear Information System (INIS)

    Carvalho, N.; Silva, W.N. da; Papaleo Netto, M.

    1973-01-01

    The effect of oral contraceptives on 131 I uptake, the depuration rate of this isotope and the PBI was studied in 24 euthyroid female patients. The dose administered was of 2.5 mg of norestinodrel and 0.05 mg of ethynil estradiol. The data were submitted to a statistical study applying analysis of variance, comparison of the means, determination of the standard deviations and the confidence interval. It is concluded that drug does affect thyroid function and that these effects may cause certain disturbances, as arterial hypertension, thrombosis, etc., in patients under prolonged contraceptive treatment [pt

  5. Biodegradation of p-nitrophenol in an aqueous waste stream by immobilized bacteria.

    OpenAIRE

    Heitkamp, M A; Camel, V; Reuter, T J; Adams, W J

    1990-01-01

    Microbiological analyses of activated sludge reactors after repeated exposure to 100 mg of p-nitrophenol (PNP) per liter resulted in the isolation of three Pseudomonas species able to utilize PNP as a sole source of carbon and energy. Cell suspensions of the three Pseudomonas sp., designated PNP1, PNP2, and PNP3, mineralized 70, 60, and 45% of a 70-mg/liter dose of PNP in 24, 48, and 96 h, respectively. Mass-balance analyses of PNP residues for all three cultures showed that undegraded PNP wa...

  6. Acute nontraumatic hemoabdomen in the dog: a retrospective analysis of 39 cases (1987-2001).

    Science.gov (United States)

    Pintar, Jason; Breitschwerdt, Edward B; Hardie, Elizabeth M; Spaulding, Kathy A

    2003-01-01

    The medical records of 39 dogs with acute nontraumatic hemoabdomen were identified and reviewed. Anemia and hypoalbuminemia were identified in 36/37 (97%) and 25/33 (76%) dogs, respectively. Coagulopathies were identified in 26/31 (84%) dogs. When a definitive diagnosis was obtained, malignant neoplasia was diagnosed most frequently and occurred in 24/30 (80%) dogs. Hemangiosarcoma accounted for 21/30 (70%) diagnoses. Sixteen dogs underwent exploratory laparotomy, of which seven (44%) survived the perioperative period. Of the dogs that did not undergo surgery, 9/23 (39%) survived to be discharged from the hospital.

  7. Intravenous infusion umbilical cord-derived mesenchymal stem cell in primary immune thrombocytopenia: A two-year follow-up

    OpenAIRE

    Wang, Xiaohua; Yin, Xiaoguang; Sun, Wei; Bai, Jin; Shen, Yawen; Ao, Qiang; Gu, Yongquan; Liu, Ying

    2017-01-01

    Four patients with chronic refractory immune thrombocytopenic purpura (ITP) received human umbilical cord-derived mesenchymal stem cells (hUC-MSCs). The hUC-MSC dose was 5?107 to 1?108. Complete remission (CR) was achieved in three patients in 12 months and one patient in 24 months. Three patients received the second hUC-MSC transplantation with the same dose. The median time between hUC-MSC transplantation and response was 12.5 days (range, 7?16). There were no severe adverse events during a...

  8. GP and staff evaluation of the maturity matrix as a tool to assess and improve organisational development in primary care

    DEFF Research Database (Denmark)

    Loegstrup, Louise; Edwards, Adrian; Waldorff, Frans Boch

    2009-01-01

    one questionnaire. At participant level, 144 returned the questionnaire: 82 GPs; 62 staff. A total of 93 gave positive statements on satisfaction with MM, 16 stated initial expectations were not met, 79 would recommend MM to colleagues. Differences between GPs and staff were only statistically...... significant regarding "increased insight into organisation of work after participation in the MM project". There was a tendency that GPs were more positive and likely to give an opinion. A total of 22 planned how to meet the goals set at the first MM meeting and 18 felt that they achieved them. In 24 out...

  9. Sexual function in lithium-treated manic-depressive patients

    DEFF Research Database (Denmark)

    Kristensen, Ellids; Jørgensen, Per

    1987-01-01

      Sexual function in 24 patients with major affective disorders who were given prophylactic lithium treatment was compared with that of a control group of surgical outpatients with no known psychiatric disease. Changes in sexual function during lithium treatment were also recorded retrospectively...... in sexual function during lithium treatment were reported by one-fourth of the patients. Of these, four reported a positive influence of the treatment and five a negative influence. Statistically, significantly more patients than controls were dissatisfied with their present sex life....

  10. Dynamic scintigraphy of esophagus in gastroesophageal reflux patients

    International Nuclear Information System (INIS)

    Foltynova, V.; Brousil, J.; Belohlavek, O.; Rehak, F.; Pafko, P.

    1988-01-01

    Scintigraphic examination of esophagus was performed in 24 patients with clinical signs of gastroesophageal reflux (GER). The results were divided into five different types of clinical findings representing different disorders in esophageal motility. The results were compared with radiological examinations, pH-metry and endoscopy. Sensitivity of the scintigraphy was 94.1%, specificity 50%, and accuracy 89.5%. The results are much better than those of radiological examinations and are comparable with pH-metry. Esophageal scintigraphy a good noninvasive method providing information about the motility of the esophagus not obtainable with other methods. (author). 8 figs., 9 refs

  11. Quantitative assessment of gastrointestinal blood loss with anti-inflammatory drugs

    International Nuclear Information System (INIS)

    Dahanukar, S.A.; Sheth, U.K.; Bhiwankar, N.T.; Ramnath, S.R.; Mehta, B.C.; Katoch, D.S.

    1980-01-01

    A comparative study of gastrointestinal blood loss caused by aspirin, flurbiprofen and RH-8 was carried out in 24 normal volunteers in whom erythrocytes were labelled with radioactive chromium i.e. Cr 51 . Blood loss was estimated by counting radio-activity in vitro taking total amount of faeces. The method used was independent of distribution of radio-activity in the faeces, which does not require homogenization. Significant increase in blood loss occurred with aspirin, flurbiprofen and RH-8; only the difference between RH-8 and flurbiprofen group is significant. (auth.)

  12. INFLUENCE OF INCUBATION TIME, GAMMA RAYS AND ELECTRON BEAM ON RADIATION RESISTANCE OF SOME SELECTED PATHOGENS

    International Nuclear Information System (INIS)

    EL-HIFNAWI, H.N.; EL-TABLAWY, S.Y.

    2009-01-01

    The effect of different growth phases on the radiation resistance, antibiotic susceptibility and pathogenicity of certain selected pathogens (Escherichia coli, Candida albicans and Staphylococcus aureus) was studied in mice. The obtained results showed that Escherichia coli was slightly more resistant to gamma radiation in 18 h than 24 h or 48 h but it was relatively more resistant to electron beam in 24 h and 48 h than 18 h. Candida albicans showed radiation resistance nearly the same in all incubation times in the case of gamma radiation while for electron beam, its radiation resistance was slightly more in 24 h and 48 h than in 18 h. On the other hand, Staphylococcus aureus recorded much more resistance to gamma radiation in the 48 h than in 24 h or 18 h whereas in the case of electron beam, it was slightly more resistant in 18 h than in 24 h and 48 h.The antibiotic susceptibility of Escherichia coli reported that the exposure to gamma radiation at 3 kGy and electron beam at 6 kGy increase the susceptibility to the nalidixic acid and nitrofurantoin. When Candida albicans was exposed to 3 kGy gamma radiation and 6 kGy electron beam, the same sensitivity to nystatin was observed in comparison with the unexposed one while the sensitivity of Staphylococcus aureus to some antibiotics (amoxicillin, nitrofurantoin and tetracycline) was decreased after exposure to gamma radiation at 0.75 and 2 kGy and electron beam at 6 kGy, but for other antibiotics (trimethoprim/ sulfamethoxazole), the sensitivity was increased at 6 kGy electron beam.The lethality percent recorded after the oral ingestion of the mice with the unexposed Escherichia coli and Candida albicans were 25% and 100%, respectively, and for 6 kGy exposure to electron beam was 0% . The cotaneous disease and abscesses caused by the intradermal injection of the mice with unexposed Staphylococcus aureus was 75% and for 6 kGy exposure to electron beam was 25%.

  13. Self-similar and self-affine pionization in nuclear interactions at a few AgeV

    International Nuclear Information System (INIS)

    Ghosh, Dipak; Deb, Argha; Chattopadhyay, Keya Dutta; Sarkar, Rinku; Dutta, Ishita Sen

    2004-01-01

    Self-affine multiplicity scaling is investigated in the framework of two-dimensional factorial moment methodology using the concept of the Hurst exponent (H) considering different bins of the phase space. We have investigated the fluctuation pattern of emitted pions in 24 Mg-AgBr interactions at 4.5 AGeV and this study reveals that the fluctuation is self-similar in some bins, whereas it is self-affine in other bins, that is, the multiplicity scaling is bin-dependent. (author)

  14. Clinico-roentgenological semiotics of malignant contact bone tumors

    International Nuclear Information System (INIS)

    Akperbekov, A.A.; Polatkhanova, K.B.; Murtuzaeva, Z.D.

    1986-01-01

    Bone changes were analyzed in 42 patients (aged 18 to 65) with malignant contact bone tumors. Probable causes of their origin were discussed. Of 42 patients corticopleural cancer (Pancoast's tumor) was noted in 24, skin cancer developing against a background of a chronic inflammatory process or trauma, was noted in 13, sarcomatous soft tissue tumors in 5. A method of roentgenography using routine and spot radiographs was used for X-ray examination of the patients. In some cases the examination was supplemented with hard and soft X-ray films, tomography and electroroentgenography

  15. Effects of HRV-Guided vs. Predetermined Block Training on Performance, HRV and Serum Hormones.

    Science.gov (United States)

    Nuuttila, Olli-Pekka; Nikander, Aku; Polomoshnov, Dmitry; Laukkanen, Jari Antero; Häkkinen, Keijo

    2017-11-01

    The aim of this study was to compare heart rate variability -guided (HRVG) and predetermined (PD) block periodization of high intensity aerobic training (HIT). Endurance performance, neuromuscular performance, heart rate variability (HRV) and serum hormone concentrations were measured before, in the middle and after the 8-week training period in 24 endurance trained males. Both groups improved significantly maximal treadmill velocity (V max ) (pHRV (RMSSD, LF and TP) increased significantly only in HRVG (pHRV and serum testosterone levels observed in HRVG, individually HRV -guided block training may be more optimal compared to predetermined training. © Georg Thieme Verlag KG Stuttgart · New York.

  16. Oral gingival metastasis: A diagnostic dilemma

    Directory of Open Access Journals (Sweden)

    Nalini Aswath

    2017-01-01

    Full Text Available Oral cavity is a rare target for metastasis with an incidence of 1% among all oral cancers. In 24% of such cases, oral metastasis is the first indication of an undiagnosed primary. Metastatic oral malignancies have been reported in the mandible, tongue, and gingiva. Although gingival metastasis has been reported from lung, prostate, rectal carcinoma in men and carcinoma of breast, adrenal glands, and genitalia in females, gingival metastasis from carcinoma of the penis has not been reported. Herein, a case of metastatic gingival carcinoma that developed after extraction of teeth from primary carcinoma of the penis is presented. An extensive literature search revealed no such similar case reports.

  17. Cerebral palsy

    International Nuclear Information System (INIS)

    Truwit, C.L.; Barkovich, A.J.; Koch, T.; Ferreiro, D.

    1990-01-01

    This paper reviews cranial MR findings in patients with cerebral palsy (CP) to clarify and categorize this disorder. The MR images of 40 patients with clinical CP were retrospectively reviewed. All patients suffered either varying spastic plegias, hypotonicity, or choreoathetosis. Concomitantly, the patients suffered from static encephalopathy, developmental delay, and/or microcephaly. Twenty-four patients were born at or near term, 10 were premature, and incomplete birth histories were available in six. The MR images revealed mild to severe degrees of white matter damage in 24 patients (12 term, nine premature, three unknown)

  18. Evaluation of flavonoids and enterolactone in overnight urine as intake biomarkers of fruits, vegetables and beverages in the Inter99 cohort study using the method of triads

    DEFF Research Database (Denmark)

    Krogholm, Kirstine Suszkiewicz; Bysted, Anette; Brantsaeter, A. L.

    2012-01-01

    in 24 h urine as an alternative and more feasible biomarker of fruit, vegetable and beverage intake. A total of 191 individuals in the Inter99 cohort in Denmark completed the validation study. Concentrations of nine urinary flavonoid aglycones (quercetin, isorhamnetin, tamarixetin, kaempferol......, hesperetin, naringenin, eriodictyol, phloretin and apigenin) and enterolactone were determined in overnight and 24 h urine samples, and their validity as biomarkers of fruit, vegetable and beverage intake was evaluated in relation to two independent reference methods (Inter99 FFQ data and plasma carotenoids...

  19. EFFECT OF SACUBITRIL/VALSARTAN ON NATRIURESIS, DIURESIS AND BLOOD PRESSURE IN HYPERTENSIVE PATIENTS

    OpenAIRE

    Zh. D. Kobalava; S. V. Villevalde; I. A. Meray; O. I. Lukina

    2017-01-01

    Aim. To study the effect of sacubitril/valsartan compared with valsartan on natriuresis, diuresis, blood pressure (BP) and the level of biomarkers in hypertensive patients.Material and methods. Hypertensive patients (n=16) received sacubitril/valsartan 400 mg QD or valsartan 320 mg QD for 7 days in a double-blind,-randomized, cross-over study. The change in 24-hour diuresis and natriuresis, fractional urinary sodium excretion, and BP level have been studied, as-well as soluble biomarkers: cyc...

  20. Donor-specific rejection: Clinical and scan correlation

    International Nuclear Information System (INIS)

    Wilson, M.A.; Mehta, R.C.; Perlman, S.B.; Servilla, K.; Sollinger, H.W.; Deierhoi, M.H.; Belzer, F.O.

    1986-01-01

    All 470 scans on 132 consecutive renal transplantation patients were reviewed. Scan patterns identified included acute tubular necrosis and conventional rejection. A new pattern, donor specific rejection (DSR), was identified in 24 of 42 patients on the living related donor specific transfusion (DST) protocol. This was characterized by good perfusion and extraction but significant renal stasis of tracer. This pattern was unique to the DST recipients and improved with antirejection therapy. The clinical features (incidence, temporal onset) and severity (duration, serum creatinines) are compared in these patient populations. DSR occurs more frequently than conventional rejection but is a milder process

  1. Morphometrical analysis of pathomorphosis of squamous cell lung carcinoma after radiotherapy combined with hyperglycemia

    International Nuclear Information System (INIS)

    Furmanchuk, A.V.; Demidchik, Yu.E.; Khodina, T.V.

    1987-01-01

    Morphological changes are analysed and morphological assessment of the parenchyma, stroma, vessels and necrosis are provided in the squamous cell lung carcinoma tissue of 40 patients without preliminary irradiation, 40 patients after γ-beam therapy and 49 patients after radiotherapy combined with induced hyperglycemia (IH). The total focal dosage was 20 Gy (5 fractions during a week). In 25 patients IH was followed by irradiation and in 24 patients it followed irradiation. Operation was performed on the 7-8th day after therapy was initiated. It was concluded that preoperative γ-beam therapy followed by IH produced the most noticeable damaging effect on squamous cell lung carcinoma

  2. Dexamethasone Protects Against Tourniquet-Induced Acute Ischemia-Reperfusion Injury in Mouse Hindlimb

    Directory of Open Access Journals (Sweden)

    Ryan M. Corrick

    2018-03-01

    Full Text Available Extremity injuries with hemorrhage have been a significant cause of death in civilian medicine and on the battlefield. The use of a tourniquet as an intervention is necessary for treatment to an injured limb; however, the tourniquet and subsequent release results in serious acute ischemia-reperfusion (IR injury in the skeletal muscle and neuromuscular junction (NMJ. Much evidence demonstrates that inflammation is an important factor to cause acute IR injury. To find effective therapeutic interventions for tourniquet-induced acute IR injuries, our current study investigated effect of dexamethasone, an anti-inflammatory drug, on tourniquet-induced acute IR injury in mouse hindlimb. In C57/BL6 mice, a tourniquet was placed on unilateral hindlimb (left hindlimb at the hip joint for 3 h, and then released for 24 h to induce IR. Three hours of tourniquet and 24 h of release (24-h IR caused gastrocnemius muscle injuries including rupture of the muscle sarcolemma and necrosis (42.8 ± 2.3% for infarct size of the gastrocnemius muscle. In the NMJ, motor nerve terminals disappeared, and endplate potentials were undetectable in 24-h IR mice. There was no gastrocnemius muscle contraction in 24-h IR mice. Western blot data showed that inflammatory cytokines (TNFα and IL-1β were increased in the gastrocnemius muscle after 24-h IR. Treatment with dexamethasone at the beginning of reperfusion (1 mg/kg, i.p. significantly inhibited expression of TNFα and IL-1β, reduced rupture of the muscle sarcolemma and infarct size (24.8 ± 2.0%, and improved direct muscle stimulation-induced gastrocnemius muscle contraction in 24-h IR mice. However, this anti-inflammatory drug did not improve NMJ morphology and function, and sciatic nerve-stimulated skeletal muscle contraction in 24-h IR mice. The data suggest that one-time treatment with dexamethasone at the beginning of reperfusion only reduced structural and functional impairments of the skeletal muscle but not the

  3. Dimensions of the prostatic and membranous urethra in normal male dogs during maximum distension retrograde urethrocystography

    International Nuclear Information System (INIS)

    Feeney, D.A.; Johnston, G.R.; Osborne, C.A.; Tomlinson, M.J.

    1984-01-01

    Prostatic and membranous urethral diameter was measured in 24 normal mature male Beagle dogs during maximum distension retrograde urethrocystography. This technique involved retrograde urethral distension by infusion with contrast medium until the urinary bladder was distended and the vesicourethral junction remained opened as observed by fluoroscopy. Lateral and ventro-dorsal radiographs were made during subsequent injections of 5–10 ml of contrast medium. The prostatic urethra was consistently greater in diameter than the membranous urethra. However, the numerical ratio between the prostatic urethral diameter and the membranous urethral diameter varied among these dogs by a factor of 2 at the numerical extremes

  4. Preferensi dan kerusakan tumbuhan koleksi Kebun Raya Cibodas oleh benalu Scurrula oortiana (Korth. Dans.

    Directory of Open Access Journals (Sweden)

    Sunaryo Sunaryo

    2012-02-01

    Full Text Available The mistletoe of Scurrula oortiana (Korth. Dans. (Loranthaceae growing on several collection plants at Cibodas Botanical Garden. The mistletoe parasite 48 species of plants collection, what come within in 24 tribe. Plants collection which attacked as thehighest is group of Ficus type (Moraceae. While attacked by individual in number at most is Callistemon citrinus (Myrtaceae. Themistletoe has caused the damage at part of branch. Infected and uninfected branches of host species were observed. The result showedthat the mistletoe causes degradation of the distal part of the infected branches. Damage value of branch which parasite of mean morethan 50%.

  5. Argon laser choroidotomy for drainage of subretinal fluid.

    Science.gov (United States)

    Bovino, J A; Marcus, D F; Nelsen, P T

    1985-03-01

    We used the argon laser to perforate the choroid and drain subretinal fluid during retinal detachment surgery in 24 consecutive patients. The procedure was successful in 23 of 24 patients (95.8%). The laser settings required for perforation ranged from 0.02 to 0.2 s and from 200 mW to 2.0 W. Because it is not necessary to enter the subretinal space with a solid, pointed object, laser choroidotomy may reduce the incidence of retinal perforation. In addition, the laser has the advantage of cauterizing small vessels during choroidal puncture, which may reduce bleeding at the time of drainage.

  6. Adrenal function in children with bronchial asthma treated with beclomethasone dipropionate or budesonide

    DEFF Research Database (Denmark)

    Bisgaard, H; Damkjaer Nielsen, M; Andersen, B

    1988-01-01

    . The unstimulated diurnal production of glucocorticosteroids was assessed by measurements of free cortisol in 24-hour urine samples. Free cortisol in urine was found a valid measure of the total diurnal excretion of cortisol metabolites, since it exhibited a good correlation to the fractional cortisol metabolites...... difference was found between the two topical steroids (probability value 5.3%), and yet the suppression was apparent in the group of children treated with beclomethasone dipropionate but not in the group of children treated with budesonide. Further studies are desirable in order to ascertain whether...

  7. Effect of biological and chemical preparations on peroxidase activity in leaves of tomato plants

    Directory of Open Access Journals (Sweden)

    Yulia Kolomiets

    2016-10-01

    Full Text Available In terms of treating tomato variety Chaika with chemical preparations with active substances if aluminum phosphate, 570 g/l + phosphorous acid 80 g/,l and mankotseb in concentration of 640 g/kg, the maximum increase in peroxidase activity in leaves of plants was observed in12 hours. In terms of use of biological preparations based on living cells Bacillus subtilis and Azotobacter chroococcum its activity was maximum in 24 hours and ranged from 77.7 to 112.7 un.mg-1•s-1

  8. Salpingitis isthmica nodosa in female infertility and tubal diseases

    DEFF Research Database (Denmark)

    Skibsted, L; Sperling, Lene; Hansen, U

    1991-01-01

    -examination, it was found in 24 patients. Ten women with SIN were bilaterally salpingectomized. Only one woman had SIN in both tubes. Women with SIN gave birth to as many children as women without SIN. After SIN had been diagnosed, no children were born, but this was not statistically different from the frequency of births...... with infertility, pregnancies, outcome of pregnancies, births, pelvic inflammatory disease and salpingitis. Sections from the isthmus were present in the specimens from 223 tubes from 193 patients and were analysed by the same pathologist. Originally, SIN was found in 12 patients but on re...

  9. Gianturco expandable wire stents for treatment of superior vena cava syndrome secondary to lung carcinoma

    International Nuclear Information System (INIS)

    Rosch, J.; Bedell, J.; Putnam, J.; Antonovic, R.; Uchida, B.

    1986-01-01

    Two patients with superior vena cava syndrome (SVCS) secondary to lung carcinoma which recurred after maximum-dose radiation therapy were treated with placement of modified Gianturco expandable wire stents constructed in the authors' research laboratory. Symptoms of SVCS disappeared in 24 hours after stent placement, and the patients remained asymptomatic to their last follow-up, 2 1/2 months after the procedure (to the submission of this abstract). Both stents were widely patent at that time on superior vena cavograms and draining well the head, neck, and upper extremity circulation to the right atrium

  10. Value of arthrography in the evaluation of sacroiliac pain

    International Nuclear Information System (INIS)

    Bobechko, P.

    1987-01-01

    The authors attempted to assess the sacroiliac joint as a source of low back pain by using arthrography with a local anesthetic injection. Intraarticular injection of contrast agent and local anesthetic was attempted in 29 patients (35 joints), aged 24-69 years. The intraarticular injection was successful in 24 cases (68.5%). Periarticular infiltration of anesthetic was done in the remaining 11 cases. Pain relief was obtained in 19 cases, of which 13 involved intraarticular and six involved periarticular injections. On the basis of these results, patients were treated by surgical fusion, medication, or conservative management. Referring physicians found that the results obtained were valuable and helpful in assessing these patients

  11. Body image and weight control in youth: 9-year international trends from 24 countries

    DEFF Research Database (Denmark)

    Quick, V.; Nansel, T.; Liu, D.

    2014-01-01

    for weight loss were assessed in the Health Behaviour in School-aged Children survey conducted in 24 countries cross-sectionally at three time points (2001/2002, 2005/2006 and 2009/2010). Logistic regression models examined change over time in overestimation of body size in non-overweight adolescents......-perceived overweight with increased odds of dieting diminished over time. CONCLUSIONS: Body size perceptions among adolescents may have changed over time concurrent with shifts in country-level body weight. However, controlling for country-level overweight prevalence did not impact trends in dieting for weight loss...

  12. Biodegradation of Trichloroethylene by an Endophyte of Hybrid Poplar

    Science.gov (United States)

    Kang, Jun Won; Khan, Zareen

    2012-01-01

    We isolated and characterized a novel endophyte from hybrid poplar. This unique endophyte, identified as Enterobacter sp. strain PDN3, showed high tolerance to trichloroethylene (TCE). Without the addition of inducers, such as toluene or phenol, PDN3 rapidly reduced TCE levels in medium from 72.4 μM to 30.1 μM in 24 h with a concurrent release of 127 μM chloride ion, and nearly 80% of TCE (55.3 μM) was dechlorinated by PDN3 in 5 days with 166 μM chloride ion production, suggesting TCE degradation. PMID:22367087

  13. Influence of Cisapride on food-stimulated gastro-oesophageal reflux: A radiological study

    International Nuclear Information System (INIS)

    Gelineck, J.; Aksglade, K.; Funch-Jensen, P.; Thommesen, P.

    1990-01-01

    The influence of Cisapride on food-stimulated gastro-oesophageal reflux meachanisms was studied in a double-blind cross-over investigation in 24 consecutive patients selected by endoscopy, 12 with microscopical evidence of gastro-oesophageal reflux and 12 with additional macroscopic oesoghagitis. 63% had food-stimulated gastro-oesophageal reflux, and Cisapride significantly reduced the tendency to gastro-oesophageal reflux and mucosal contact time between gastric content and the oesophageal mucosa in 73% of these patients. It is concluded that Cisapride could be valuable in the treatment of gastro-oesophageal reflux. (orig.) [de

  14. Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products

    CSIR Research Space (South Africa)

    Zimmermann, S

    2014-03-01

    Full Text Available ,β-unsaturated nucleophilic enoate groups at C13 and C3' in 1 with trypanothione and glutathione in trypanosomes corroborated the long presumed mode of action of STLs, in addition to an inhibition of ornithine decarboxylase [8]. The same mode of action can be expected... control group of four mice was infected, but remained untreated. The determination of the parasitaemia was done on day 7 post infection. 6 μL of tail blood were diluted in 24 μL sodium citrate (3.2%), whereby the first μL was discarded to obtain...

  15. Intravital and post-mortem CT examinations of cerebral gunshot injuries

    International Nuclear Information System (INIS)

    Schumacher, M.; Oehmichen, M.; Koenig, H.G.; Einighammer, H.; Koeln Univ.; Tuebingen Univ.; Duesseldorf Univ.

    1983-01-01

    The value of CT was assessed in 24 patients who died of cerebral gun-shot injuries and in two patients with more recent injuries in order to reconstruct the mode of injury and for adding forensic information. The post-mortem and intravital appearances are described and are compared with ultrasound rotation compound scans of the isolated brains. CT showed good agreement with pathological findings. Ultrasound produced images with an accuracy between CT and photographs of the brain specimen. Both methods are regarded as valuable additions to the pathological and forensic information concerning gunshot injuries. (orig.) [de

  16. Bank Risk Profile, Good Corporate Governance And Company Values in Banking Companies Go Public in Indonesia

    OpenAIRE

    Susi Retna Cahyaningtyas; Elin Erlina Sasanti; Wahidatul Husnaini

    2017-01-01

    The latest Bank Indonesia Regulation No.14/18/PBI/2012 requires bank to have minimum capital of 8%-14% depends on the risk profile of each bank. Therefore, the main objective of this research is to assess whether the total of inherent risk profile of each bank meets the terms of this regulation. In addition, this study aims to examine the impact of inherent risk profile and GCG on the banking company value. The sample in this study is determined by purposive sampling method and resulted in 24...

  17. Cobalt release and complications resulting from the use of dental prostheses

    DEFF Research Database (Denmark)

    Al-Imam, Hiba; Benetti, Ana R.; Özhayat, Esben B.

    2016-01-01

    of the functional prostheses released cobalt, whereas this was observed in 24 of 32 non-functional prostheses. None of the patients had contact allergy to cobalt. Of the 66 patients, 11 showed signs of inflammation of the oral mucosa, 2 had oral candidiasis, 16 had ill-fitting prostheses, and all had insufficient...... oral hygiene. CONCLUSIONS: Dental prostheses released cobalt during the fabrication stages, but not 1-5 years after insertion. No allergic reactions were observed. Signs of inflammation were related to candidiasis, insufficient oral hygiene, and ill-fitting prostheses....

  18. The validity of the negative binomial multiplicity distribution in the case of the relativistic nucleus-nucleus interaction

    International Nuclear Information System (INIS)

    Ghosh, D.; Mukhopadhyay, A.; Ghosh, A.; Roy, J.

    1989-01-01

    This letter presents new data on the multiplicity distribution of charged secondaries in 24 Mg interactions with AgBr at 4.5 GeV/c per nucleon. The validity of the negative binomial distribution (NBD) is studied. It is observed that the data can be well parametrized in terms of the NBD law for the whole phase space and also for different pseudo-rapidity bins. A comparison of different parameters with those in the case of h-h interactions reveals some interesting results, the implications of which are discussed. (orig.)

  19. Scintigraphic investigation of clavicular bone area in patients with psoriasis

    International Nuclear Information System (INIS)

    Aso, Kazuo; Amano, Michiko; Sekiya, Sakae; Komatani, Akio

    1984-01-01

    Bone scintigraphy with sup(99m)Tc-methylene diphosphonate (MDP) was performed in 38 patients with psoriasis, 5 patients with palmoplantar pustulosis, and 56 control subjects. Abnormal uptake was seen primarily in the sternoclavicular junction and the cartilage of the first rib in 24 of the patients with psoriasis (63%) and in 3 of the patients with palmoplantar pustulosis (60%), and in the sternoclavicular junction in 21 of the control subjects (38%). The incidence of uptake in the sternoclavicular junction area in the psoriasis patients clearly exceeded that in the control subjects. (Namekawa, K.)

  20. [Study on effect of pH on rectum permeability of active ingredients in Reduning suppositories in vitro].

    Science.gov (United States)

    Yan, Ming; Wei, Ying-chun; Meng, Jin; Xu, Dian-hong; Wu, Yun; Xiao, Wei

    2015-04-01

    To investigate the effect of different pH on rectum permeability of chlorogenic acid and geniposide. Four kinds of Reduning suppositories of different pH were separated and put into the rectum to study the suppositories in vitro and the content of chlorogenic acid and geniposide samples was determined by HPLC to calculate the permeation in 24 hours. With increase of pH within 2.5-7.4, the steady state flux of chlorogenic acid was increased, but the steady state flux of geniposidesamples was steady. Adjusted the pH can increase the rectum permeability of active ingredients in Reduning auppositories.