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Sample records for improved quench localization

  1. Improved Quench Localization and Quench Propagation Velocity Measurements in the LHC Superconducting Dipole Magnets

    CERN Document Server

    Calvi, M; Kouzue, S; Siemko, A

    2005-01-01

    The series tests performed on the LHC superconducting magnets at cryogenic condition give a unique opportunity to understand the mechanisms responsible for the instabilities causing the so-called training quenches. The first series production tests demonstrated that the weak points in the LHC dipoles are the coil extremities in which the majority of the quenches are located. This evidence triggered the idea of improving the resolution of the measuring system to better characterize the starting region of a quench and the beginning of its propagation. The new quench antennas equipped with sets of small, 4 cm long, and sensitive pick-up coils were designed. The system is described in detail and the first measurement results are presented. It turned out that this tool is also a reliable technique for measuring the quench propagation velocity especially in the particular regions of the superconducting coils like the crossing between the straight section of the magnet and its extremity.

  2. Strong Anderson localization in cold atom quantum quenches

    OpenAIRE

    Micklitz, T.; Müller, C. A.; Altland, A.

    2013-01-01

    Signatures of strong Anderson localization in the momentum distribution of a cold atom cloud after a quantum quench are studied. We consider a quasi one-dimensional cloud initially prepared in a well defined momentum state, and expanding for some time in a disorder speckle potential. Anderson localization leads to a formation of a coherence peak in the \\emph{forward} scattering direction (as opposed to the common weak localization backscattering peak). We present a microscopic, and fully time...

  3. Universal Dynamics of a localized excitation after an interaction quench

    Science.gov (United States)

    Franchini, Fabio; Fabio Franchini Team; Manas Kulkarni Team; Andrey Gromov Team; Andrea Trombettoni Team

    We study the time evolution -induced by a quench- of local excitations in one dimension. We focus on interaction quenches: the considered protocol consists in creating a stable localized excitation propagating through the system, and then operating a sudden change of the interaction between the particles. To highlight the effect of the quench, we take the initial excitation to be a soliton. The quench splits the excitation into two packets moving in opposite directions, whose characteristics can be expressed in a universal way. Our treatment, which is hydrodynamic in nature, allows to describe the internal dynamics of these two packets in terms of the different velocities of their components. We confirm our analytical predictions through numerical simulations performed with the Gross-Pitaevskii equation and with the Calogero model (as an example of long range interactions and solvable with a parabolic confinement). Through the Calogero model we also discuss the effect of an external trapping on the protocol. The hydrodynamic approach shows that there is a difference between the bulk velocities of the propagating packets and the velocities of their peaks, accessible through different measurement procedures. H2020 Twinning project No. 692194, \\x98RBIT-WINNING; FP7 Marie Curie PIOF-PHY-276093; CUNY Award award # 68193-00 46; European Project Matterwave.

  4. Strong Anderson localization in cold atom quantum quenches.

    Science.gov (United States)

    Micklitz, T; Müller, C A; Altland, A

    2014-03-21

    Signatures of Anderson localization in the momentum distribution of a cold atom cloud after a quantum quench are studied. We consider a quasi-one-dimensional cloud initially prepared in a well-defined momentum state, and expanding for some time in a disorder speckle potential. Quantum interference generates a peak in the forward scattering amplitude which, unlike the common weak localization backscattering peak, is a signature of strong Anderson localization. We present a nonperturbative, and fully time resolved description of the phenomenon, covering the entire diffusion-to-localization crossover. Our results should be observable by present day experiments.

  5. Transition edge sensors for quench localization in SRF cavity tests

    Science.gov (United States)

    Furci, H.; Kovács, Z.; Koettig, T.; Vandoni, G.

    2017-12-01

    Transition Edge Sensors (TES) are bolometers based on the gradual superconducting transition of a thin film alloy. In the frame of improvement of non-contact thermal mapping for quench localisation in SRF cavity tests, TES have been developed in-house at CERN. Based on modern photolithography techniques, a fabrication method has been established and used to produce TES from Au-Sn alloys. The fabricated sensors superconducting transitions were characterised. The sensitive temperature range of the sensors spreads over 100 mK to 200 mK and its centre can be shifted by the bias current applied between 1.5 K and 2.1 K. Maximum sensitivity being in the range of 0.5 mV/mK, it is possible to detect fast temperature variations (in the 50 μs range) below 1 mK. All these characteristics are an asset for the detection of second sound. Second sound was produced by heaters and the TES were able to distinctively detect it. The value of the speed of second sound was determined and corresponds remarkably with literature values. Furthermore, there is a clear correlation between intensity of the signal and distance, opening possibilities for a more precise signal interpretation in quench localisation.

  6. Infinitely robust order and local order-parameter tulips in Apollonian networks with quenched disorder

    Science.gov (United States)

    Kaplan, C. Nadir; Hinczewski, Michael; Berker, A. Nihat

    2009-06-01

    For a variety of quenched random spin systems on an Apollonian network, including ferromagnetic and antiferromagnetic bond percolation and the Ising spin glass, we find the persistence of ordered phases up to infinite temperature over the entire range of disorder. We develop a renormalization-group technique that yields highly detailed information, including the exact distributions of local magnetizations and local spin-glass order parameters, which turn out to exhibit, as function of temperature, complex and distinctive tulip patterns.

  7. Reduction of Residual Stress and Improvement of Dimensional Accuracy by Uphill Quenching for Al6061 Tube

    Science.gov (United States)

    Lim, Hak-Jin; Ko, Dae-Hoon; Ko, Dae-Cheol; Kim, Byung-Min

    2014-04-01

    The purpose of this study is to reduce the residual stress and machining distortion of an Al6061 tube by using uphill quenching. During uphill quenching, solid-solution heat-treated aluminum parts are usually immersed in LN2 at 77 K (-196 °C), followed by the rapid heating of the parts, to produce a new residual stress that is opposite in nature to the original. The uphill quenching method used in this study employed two types of heating methods: boiling water at 373 K (100 °C) and high-velocity steam at 448 K (175 °C). First, FE-simulation coupled with a CFD analysis was performed to predict the residual stress of the backward hot-extruded Al6061 tube with the following dimensions: Ø200 mm × h200 mm × t10 mm. Experiment of uphill quenching was also conducted to measure the residual stress using the boiling water and high-velocity steam uphill quenching methods. The predicted residual stresses were compared with the experimental results obtained via micro-indentation and saw-cutting tests, and a deviation of about 10.4 pct was found. In addition, the experimental results showed that uphill quenching could relieve up to 91 pct of the residual stress induced by water quenching. Finally, the dimensional accuracy of uphill quenched tubes was evaluated by measuring the roundness after the machining process, which showed that the uphill quenching method could improve the dimensional accuracy of an Al6061 tube by reducing the residual stress.

  8. Scaling study of an improved fermion action on quenched lattices

    CERN Document Server

    Cho, Yong-Gwi; Noaki, Jun-Ichi; Kaneko, Takashi; Jüttner, Andreas; Tsang, Justus; Marinkovic, Marina

    2014-01-01

    We present scaling studies for heavy-quark observables calculated with an $O(a^2)$-improved fermion action on tree-level Symanzik improved gauge configurations. Lattices of $1/a = $ 2.0-3.8 GeV with an equal physical volume 1.6 fm are used. The results are compared with the standard domain-wall and naive Wilson fermions.

  9. A fiber optic strain measurement and quench localization for use in superconducting accelerator dipole magnets

    International Nuclear Information System (INIS)

    van Oort, J.M.; Scanlan, R.M.; ten Kate, H.H.J.

    1994-01-01

    A novel fiber-optic measurement system for superconducting accelerator magnets is described. The principal component is an extrinsic Fabry-Perot Interferometer to determine localized strain and stress in coil windings. The system can be used either as a sensitive relative strain measurement system or as an absolute strain detector. Combined, one can monitor the mechanical behaviour of the magnet system over time during construction, long time storage and operation. The sensing mechanism is described, together with various tests in laboratory environments. The test results of a multichannel test matrix to be incorporated first in the dummy coils and then in the final version of a 13T Nb 3 Sn accelerator dipole magnet are presented. Finally, the possible use of this system as a quench localization system is proposed

  10. Beta-quenching of zircaloy cladding tubes in intermediate or final size - methods to improve corrosion and mechanical properties

    International Nuclear Information System (INIS)

    Andersson, Th.; Vesterhund, G.

    1982-01-01

    Three batches of Zicaloy-2 tubing were beta-quenched prior to the final cold-rolling, cold rolled 80 percent, and annealed at 475 to 575 degree C. A fourth batch was /beta/-quenched in the final size. Beta-quenching instead of an intermediate or the final anneal results in significant stuctural changes. In high-pressure steam at 475 degree C such /beta/-quenching has a dramatic beneficial effect on the corrosion resistance. The short term strength as measured in tension and burst testing is improved by /beta/-quenching of hollows or finished tubes, whereas such treatment results in a slight drop in ductility, especially for tubing /beta/107 -quenched in the final size. The 400 degree celluis transverse creep strength is increased by the introduction of /beta/-quenching prior to the final cold-rolling. The improvement is caused mainly by small second-phase particles, formed during /beta/-quenching, which give rise to precipitation hardening. 5 refs

  11. Star Formation, Quenching And Chemical Enrichment In Local Galaxies From Integral Field Spectroscopy

    Science.gov (United States)

    Belfiore, Francesco

    2017-08-01

    Within the currently well-established ΛCDM cosmological framework we still lack a satisfactory understanding of the processes that trigger, regulate and eventually quench star formation on galactic scales. Gas flows (including inflows from the cosmic web and supernovae-driven outflows) are considered to act as self-regulatory mechanisms, generating the scaling relations between stellar mass, star formation rate and metallicity observed in the local Universe by large spectroscopic surveys. These surveys, however, have so far been limited by the availability of only one spectrum per galaxy. The aim of this dissertation is to expand the study of star formation and chemical abundances to resolved scales within galaxies by using integral field spectroscopy (IFS) data, mostly from the ongoing SDSS-IV MaNGA survey. In the first part of this thesis I demonstrate the ubiquitous presence of extended low ionisation emission-line regions (LIERs) in both late- and early-type galaxies. By studying the Hα equivalent width and diagnostic line ratios radial profiles, together with tracers of the underlying stellar population, I show that LIERs are not due to a central point source but to hot evolved (post-asymptotic giant branch) stars. In light of this, I suggest a new classification scheme for galaxies based on their line emission. By analysing the colours, star formation rates, morphologies, gas and stellar kinematics and environmental properties of galaxies with substantial LIER emission, I identify two distinct populations. Galaxies where the central regions are LIER-like, but show star formation at larger radii are late types in which star formation is slowly quenched inside-out. This transformation is associated with massive bulges. Galaxies dominated by LIER emission at all radii, on the other hand, are red-sequence galaxies harbouring a residual cold gas component, acquired mostly via external accretion. Quiescent galaxies devoid of line emission reside in denser

  12. Understanding the physics of gas stripping and star-formation quenching of the satellite dwarf galaxies in the Local Group

    Science.gov (United States)

    Wetzel, Andrew

    2017-08-01

    The Milky Way (MW) and M31 are among the best systems to study the physics of the halo environment on galaxy evolution. Nearly all of the satellite dwarf galaxies of the MW and M31 are gas-poor and have quenched star formation. Over 1200 orbits of HST observations of these satellites now provide detailed star-formation histories and proper-motion velocities for full 6-D orbital phase-space, informing both when and where each satellite quenched. However, the lack of sufficiently realistic theoretical models of gas stripping represents a severe limitation to leveraging the astrophysical returns of these HST observations.We propose to use the new Latte cosmological zoom-in hydrodynamic simulations of MW- and M31-mass systems to understand the environmental processes that strip gas from satellite dwarf galaxies and quench their star formation. Our initial Latte simulations form realistic satellite populations, with star-formation histories that agree well HST measurements. These simulations use the state-of-the-art FIRE model for star formation and feedback: this feedback drives strong gas outflows within dwarf galaxies that can enhance the efficiency of ram-pressure stripping within the halo. We will run a new suite of simulations carefully targeted to the Local Group, and we will investigate how the combination of internal feedback and external stripping leads to rapid quenching, as observed by HST. Finally, we will publicly release our satellite galaxy/subhalo catalogs, including their full orbital and star-formation histories, to compare with existing/upcoming HST observations, providing detailed insight into the physics of environmental quenching.

  13. Improvement of Weldment Properties by Hot Forming Quenching of Friction Stir Welded TWB Sheet

    Directory of Open Access Journals (Sweden)

    Dae-Hoon Ko

    2014-04-01

    Full Text Available The purpose of this study is to improve the mechanical properties and formability of friction stir welded tailor-welded blanks (TWBs of Al6061 alloy with a new forming method called hot forming quenching (HFQ in which solid-solution heat-treated aluminum sheets are formed at elevated temperature. Forming and quenching during HFQ are simultaneously performed with the forming die for the solid-solution heat-treated sheet. In this study, specimens of aluminum TWBs were prepared by friction stir welding (FSW with a butt joint. The effectiveness of FSW joining was evaluated by observation of the macrostructure for different sheet thicknesses. In order to evaluate the formability of TWBs by HFQ, a hemisphere dome stretching test of the limit dome height achieved without specimen failure was performed with various tool temperatures. A Vickers test was also performed to measure weldment hardness as a function of position. The formability and mechanical properties of products formed by HFQ are compared with those formed by conventional forming methods, demonstrating the suitability of HFQ for sheet metal forming of friction stir welded TWBs.

  14. Improvement of Anisotropic Mechanical Behavior by Sulfide Control in Quenched and Tempered 4340 Steel

    Science.gov (United States)

    Jung, Jae-Hoon; Shin, Jung-Ho; Lee, Seok-Jae

    2015-07-01

    The anisotropic mechanical behavior of quenched and tempered 4340 steel with different Ca contents was investigated by means of a macro/micrograph analysis, Charpy impact test, and rotating bending fatigue test. The 4340 steel with Ca added formed small spherical (Ca,Mn)S inclusions and effectively decreased both the inclusion size and the aspect ratio (length to width) of the MnS inclusions as compared to the Ca-free 4340 steel. The anisotropic impact value and fatigue strength were effectively improved due to the Ca addition that prevented the growth of MnS inclusions, which provided increased resistance against deformation to maintain a spherical shape because the elongated MnS inclusions acted as a crack propagation path and promoted the crack propagation due to higher stress concentrations.

  15. Quench limits

    International Nuclear Information System (INIS)

    Sapinski, M.

    2012-01-01

    With thirteen beam induced quenches and numerous Machine Development tests, the current knowledge of LHC magnets quench limits still contains a lot of unknowns. Various approaches to determine the quench limits are reviewed and results of the tests are presented. Attempt to reconstruct a coherent picture emerging from these results is taken. The available methods of computation of the quench levels are presented together with dedicated particle shower simulations which are necessary to understand the tests. The future experiments, needed to reach better understanding of quench limits as well as limits for the machine operation are investigated. The possible strategies to set BLM (Beam Loss Monitor) thresholds are discussed. (author)

  16. Holographic entanglement entropy of local quenches in AdS4/CFT3: a finite-element approach

    Science.gov (United States)

    Jahn, Alexander; Takayanagi, Tadashi

    2018-01-01

    Understanding quantum entanglement in interacting higher-dimensional conformal field theories is a challenging task, as direct analytical calculations are often impossible to perform. With holographic entanglement entropy, calculations of entanglement entropy turn into a problem of finding extremal surfaces in a curved spacetime, which we tackle with a numerical finite-element approach. In this paper, we compute the entanglement entropy between two half-spaces resulting from a local quench, triggered by a local operator insertion in a CFT3. We find that the growth of entanglement entropy at early time agrees with the prediction from the first law, as long as the conformal dimension Δ of the local operator is small. Within the limited time region that we can probe numerically, we observe deviations from the first law and a transition to sub-linear growth at later time. In particular, the time dependence at large Δ shows qualitative differences to the simple logarithmic time dependence familiar from the CFT2 case. We hope that our work will motivate further studies, both numerical and analytical, on entanglement entropy in higher dimensions.

  17. An Efficient Fluid-Dynamic Analysis to Improve Industrial Quenching Systems

    Directory of Open Access Journals (Sweden)

    Manuel de J. Barrena-Rodríguez

    2017-05-01

    Full Text Available This paper addresses the problem of understanding the relationship between fluid flow and heat transfer in industrial quenching systems. It also presents an efficient analysis to design or optimize long standing quenching tanks to increase productivity. The study case is automotive leaf springs quenched in an oil-tank agitated with submerged jets. This analysis combined an efficient numerical prediction of the detailed isothermal flow field in the whole tank with the thermal characterization of steel probes in plant and laboratory during quenching. These measurements were used to determine the heat flow by solving the inverse heat conduction problem. Differences between laboratory and plant heat flux results were attributed to the difference in surface area size between samples. A proposed correlation between isothermal wall shear stress and heat flux at the surface of the steel component, based on the Reynolds-Colburn analogy, provided the connection between thermal characterization and computed isothermal fluid flow. The present approach allowed the identification of the potential benefits of changes in the tank design and the evaluation of operating conditions while using a much shorter computing time and storage memory than full-domain fluid flow calculations.

  18. Quench origins

    International Nuclear Information System (INIS)

    Devred, A.

    1990-03-01

    Quenches can be divided into two categories; conductor-limited and energy-deposited quenches. A conductor-limited quench occurs when the current in the magnet exceeds the capacity of the superconductor; it is characterized by a strong correlation with temperature. An energy-deposited quench occurs when a disturbance releases enough energy to trigger a quench; the main disturbances during magnet energization are frictional movements of the conductor due to increasing Lorentz forces. The current level of the conductor-limited quenches defines the limit of the magnet performance, and can only be surpassed by lowering the operating temperature; the occurrence of a constant current at quench during the magnetic testing is called a plateau. Usually it takes a few energy-deposited quenches of increasing currents to reach the plateau; these first few steps are called the magnet's training. The goal in designing a magnet is to be able to energize it and to reliably operate it at the design current without training. This can be achieved by optimizing the magnet's operating margin, that is, by designing and building the magnet in such a way that the sizes of the mechanical disturbances needed to trigger a quench are much larger than the achievable mechanical tolerances. (N.K.) 112 refs

  19. The beta-decay of 48Mn: improved data on Gamow-Teller quenching

    International Nuclear Information System (INIS)

    Szerypo, J.; Bazin, D.; Brown, B.A.

    1991-01-01

    Beta-decay studies of very proton-rich nuclides allow to investigate the phenomenon of quenching of Gamow-Teller transitions. A presentation of the experimental techniques is followed by the discussion of preliminray results of the measurements in comparison to shell-model calculations. A corresponding reinvestigation is discussed. A mass-separated 48 Mn beam was used from 12 C( 40 Ca,p3n) reactions. The 48 Mn decay spectroscopy was performed simultaneously in two beam lines of the mass separator. (G.P.) 13 refs.; 2 figs

  20. Non-perturbative renormalization of the static vector current and its O(a)-improvement in quenched QCD

    Energy Technology Data Exchange (ETDEWEB)

    Palombi, F.

    2007-06-15

    We carry out the renormalization and the Symanzik O(a)-improvement programme for the static vector current in quenched lattice QCD. The scale independent ratio of the renormalization constants of the static vector and axial currents is obtained non-perturbatively from an axial Ward identity with Wilson-type light quarks and various lattice discretizations of the static action. The improvement coefficients c{sub V}{sup stat} and b{sub V}{sup stat} are obtained up to O(g{sub 4}{sup 0})-terms by enforcing improvement conditions respectively on the axial Ward identity and a three-point correlator of the static vector current. A comparison between the non-perturbative estimates and the corresponding one-loop results shows a non-negligible effect of the O(g{sub 4}{sup 0})-terms on the improvement coefficients but a good accuracy of the perturbative description of the ratio of the renormalization constants. (orig.)

  1. Vacuum structure revealed by over-improved stout-link smearing compared with the overlap analysis for quenched QCD

    Energy Technology Data Exchange (ETDEWEB)

    Ilgenfritz, E.M.; Leinweber, D.; Moran, P. [Adelaide Univ., SA (AU). Special Research Centre for the Subatomic Structure of Matter (CSSM); Koller, K. [Muenchen Univ. (Germany). Sektion Physik; Schierholz, G. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Weinberg, V. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Freie Univ. Berlin (Germany). Inst. fuer Theoretische Physik

    2008-01-11

    A detailed comparison is made between the topological structure of quenched QCD as revealed by the recently proposed over-improved stout-link smearing in conjunction with an improved gluonic definition of the topological density on one hand and a similar analysis made possible by the overlap-fermionic topological charge density both with and without variable ultraviolet cutoff {lambda}{sub cut}. The matching is twofold, provided by fitting the density-density two-point functions on one hand and by a point-by-point fitting of the topological densities according to the two methods. We point out the similar cluster structure of the topological density for moderate smearing and 200 MeV<{lambda}{sub cut}<600 MeV, respectively. We demonstrate the relation of the gluonic topological density for extensive smearing to the location of the overlap zero modes and the lowest overlap non-zero mode as found for the unsmeared configurations. (orig.)

  2. Improved Intelligent Vehicle Localization Using Magnetic Ruler

    Directory of Open Access Journals (Sweden)

    Chunxiang Wang

    2011-05-01

    Full Text Available This paper proposes an improved intelligent vehicle localization method, which integrates the data from the odometry and the magnetic ruler(MR. The MR is used to detect the magnetic markers, which provides the absolute positioning reference. The data from odometry and the MR are used to localize the vehicle by using unscented Kalman filter. The data association (DA method is adopted to validate the observations from the MR. The experiment results show that the method is a robust way.

  3. Improving energy efficiency for local energy systems

    International Nuclear Information System (INIS)

    Oh, Se-Young; Binns, Michael; Yeo, Yeong-Koo; Kim, Jin-Kuk

    2014-01-01

    Highlights: • Multi-period design methodology for heat recovery in local energy systems. • A systematic targeting for minimum utility requirements for urban utility systems. • Integration of industrial waste heat with local energy systems. • A case study providing insights for the heat recovery of discontinuous systems. - Abstract: This study aims to develop a novel design method for reducing the energy consumption and CO 2 emissions of local energy systems, simultaneously considering the recovery of industrial waste heat, and effectively dealing with the non-continuous nature of energy usage and heat recovery. A multi-period concept has been adopted for characterizing the change of heat demand and associated heat recovery in local energy systems which is used for targeting of the minimum energy consumption. In addition, techno-economic analysis is used to provide design guidelines for better heat integration. This design methodology also incorporates the impacts of heat storage and part-load performance of energy production equipment. Opportunities for utilization of low grade heat in process industries have been systematically considered for the minimization of energy generation in local energy systems together with the evaluation of the economic feasibility of such systems for integration of industrial low grade heat with local energy systems. Case studies are used to demonstrate the applicability and practicality of the heat integration methodology developed in this work, and to illustrate how a holistic approach can improve the overall energy efficiency of local energy systems

  4. On Improving Local Search for Unsatisfiability

    Directory of Open Access Journals (Sweden)

    David Pereira

    2009-10-01

    Full Text Available Stochastic local search (SLS has been an active field of research in the last few years, with new techniques and procedures being developed at an astonishing rate. SLS has been traditionally associated with satisfiability solving, that is, finding a solution for a given problem instance, as its intrinsic nature does not address unsatisfiable problems. Unsatisfiable instances were therefore commonly solved using backtrack search solvers. For this reason, in the late 90s Selman, Kautz and McAllester proposed a challenge to use local search instead to prove unsatisfiability. More recently, two SLS solvers - Ranger and Gunsat - have been developed, which are able to prove unsatisfiability albeit being SLS solvers. In this paper, we first compare Ranger with Gunsat and then propose to improve Ranger performance using some of Gunsat's techniques, namely unit propagation look-ahead and extended resolution.

  5. Improved thermal quenching of Y{sub 3}Al{sub 5}O{sub 12}:Ce phosphor ceramics with silica addition

    Energy Technology Data Exchange (ETDEWEB)

    Nien, Yung-Tang, E-mail: ytnien@nfu.edu.tw; You, Jyun-Kai

    2016-09-05

    Y{sub 3}Al{sub 5}O{sub 12}:Ce (YAG:Ce) is widely used in light emitting diodes (LEDs) for the conversion of blue light into yellow light. However, thermal quenching has become a severe problem for high-power LEDs because more heat is generated by high-power LED chips; this results in the reduction of emission intensity and unit life. In this research, silica was fired with co-precipitated YAG:Ce phosphor ceramics to study the photoluminescent thermal quenching behavior by comparing with pristine YAG:Ce. The results showed that silica-added YAG:Ce phosphor ceramics exhibited an increase of more than 15% in quantum efficiency and a higher thermal quenching temperature compared with pristine YAG:Ce. This improvement in thermal stability (10% increase at 150 °C) in silica-added YAG:Ce phosphor ceramics was attributed to a denser microstructure and an increase in thermal activation energy by Si substitution of Al in the host. - Highlights: • An increase of 15% in quantum efficiency (from 32.4% to 47.4%) is achieved. • A lower emission intensity reduction at 150 °C (from 30% to 20%) is obtained. • Si induced a denser microstructure and an increase in thermal activation energy.

  6. Tactile feedback improves auditory spatial localization.

    Science.gov (United States)

    Gori, Monica; Vercillo, Tiziana; Sandini, Giulio; Burr, David

    2014-01-01

    Our recent studies suggest that congenitally blind adults have severely impaired thresholds in an auditory spatial bisection task, pointing to the importance of vision in constructing complex auditory spatial maps (Gori et al., 2014). To explore strategies that may improve the auditory spatial sense in visually impaired people, we investigated the impact of tactile feedback on spatial auditory localization in 48 blindfolded sighted subjects. We measured auditory spatial bisection thresholds before and after training, either with tactile feedback, verbal feedback, or no feedback. Audio thresholds were first measured with a spatial bisection task: subjects judged whether the second sound of a three sound sequence was spatially closer to the first or the third sound. The tactile feedback group underwent two audio-tactile feedback sessions of 100 trials, where each auditory trial was followed by the same spatial sequence played on the subject's forearm; auditory spatial bisection thresholds were evaluated after each session. In the verbal feedback condition, the positions of the sounds were verbally reported to the subject after each feedback trial. The no feedback group did the same sequence of trials, with no feedback. Performance improved significantly only after audio-tactile feedback. The results suggest that direct tactile feedback interacts with the auditory spatial localization system, possibly by a process of cross-sensory recalibration. Control tests with the subject rotated suggested that this effect occurs only when the tactile and acoustic sequences are spatially congruent. Our results suggest that the tactile system can be used to recalibrate the auditory sense of space. These results encourage the possibility of designing rehabilitation programs to help blind persons establish a robust auditory sense of space, through training with the tactile modality.

  7. Tactile feedback improves auditory spatial localization

    Directory of Open Access Journals (Sweden)

    Monica eGori

    2014-10-01

    Full Text Available Our recent studies suggest that congenitally blind adults have severely impaired thresholds in an auditory spatial-bisection task, pointing to the importance of vision in constructing complex auditory spatial maps (Gori et al., 2014. To explore strategies that may improve the auditory spatial sense in visually impaired people, we investigated the impact of tactile feedback on spatial auditory localization in 48 blindfolded sighted subjects. We measured auditory spatial bisection thresholds before and after training, either with tactile feedback, verbal feedback or no feedback. Audio thresholds were first measured with a spatial bisection task: subjects judged whether the second sound of a three sound sequence was spatially closer to the first or the third sound. The tactile-feedback group underwent two audio-tactile feedback sessions of 100 trials, where each auditory trial was followed by the same spatial sequence played on the subject’s forearm; auditory spatial bisection thresholds were evaluated after each session. In the verbal-feedback condition, the positions of the sounds were verbally reported to the subject after each feedback trial. The no-feedback group did the same sequence of trials, with no feedback. Performance improved significantly only after audio-tactile feedback. The results suggest that direct tactile feedback interacts with the auditory spatial localization system, possibly by a process of cross-sensory recalibration. Control tests with the subject rotated suggested that this effect occurs only when the tactile and acoustic sequences are spatially coherent. Our results suggest that the tactile system can be used to recalibrate the auditory sense of space. These results encourage the possibility of designing rehabilitation programs to help blind persons establish a robust auditory sense of space, through training with the tactile modality.

  8. Three-dimensional autoradiographic localization of quench-corrected glycine receptor specific activity in the mouse brain using 3H-strychnine as the ligand

    International Nuclear Information System (INIS)

    White, W.F.; O'Gorman, S.; Roe, A.W.

    1990-01-01

    The autoradiographic analysis of neurotransmitter receptor distribution is a powerful technique that provides extensive information on the localization of neurotransmitter systems. Computer methodologies are described for the analysis of autoradiographic material which include quench correction, 3-dimensional display, and quantification based on anatomical boundaries determined from the tissue sections. These methodologies are applied to the problem of the distribution of glycine receptors measured by 3H-strychnine binding in the mouse CNS. The most distinctive feature of this distribution is its marked caudorostral gradient. The highest densities of binding sites within this gradient were seen in somatic motor and sensory areas; high densities of binding were seen in branchial efferent and special sensory areas. Moderate levels were seen in nuclei related to visceral function. Densities within the reticular formation paralleled the overall gradient with high to moderate levels of binding. The colliculi had low and the diencephalon had very low levels of binding. No binding was seen in the cerebellum or the telencephalon with the exception of the amygdala, which had very low levels of specific binding. This distribution of glycine receptors correlates well with the known functional distribution of glycine synaptic function. These data are illustrated in 3 dimensions and discussed in terms of the significance of the analysis techniques on this type of data as well as the functional significance of the distribution of glycine receptors

  9. Improving safety on rural local and tribal roads safety toolkit.

    Science.gov (United States)

    2014-08-01

    Rural roadway safety is an important issue for communities throughout the country and presents a challenge for state, local, and Tribal agencies. The Improving Safety on Rural Local and Tribal Roads Safety Toolkit was created to help rural local ...

  10. Magnet Quench 101

    OpenAIRE

    Bottura, L.

    2014-01-01

    This paper gives a broad summary of the physical phenomena associated with the quench of a superconducting magnet. This paper gives a broad summary of the physical phenomena associated with the quench of a superconducting magnet.

  11. Quenches after LS1

    International Nuclear Information System (INIS)

    Verweij, A.P.

    2012-01-01

    In this paper I will give an overview of the different types of quenches that occur in the LHC, followed by an estimate of the number of quenches that we can expect after LS1. Beam-induced quenches and false triggering of the QPS will be the main cause of those quenches that cause a beam dump. Possibly in total up to 10-20 per year. After consolidation of the 13 kA joints, the approach for the BLM settings can be less conservative than in 2010-2012 in order to maximize beam time. This will cause some quenches but, anyhow, a beam.induced quench is not more risky than a quench provoked by false triggering. It is not easy to predict the number of BLM triggered beam dumps, needed to avoid magnet quenches, because it is not sure how to scale beam losses and UFO's from 3.5 TeV to 6.5 TeV, and it is not sure if the thresholds at 3.5 TeV are correct. Quench events will be much more massive (ex: RB quench at 6 kA → 2 MJ, RB quench at 11 kA → 6-20 MJ), and as a result cryo recuperation much longer. There will also be more ramp induced quenches after a FPA in other circuits due to higher ramp rates and smaller temperature margins (mutual coupling)

  12. Improving Local Government Accountability for Poor and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Creating stronger links could help formal mechanisms be more responsive to local needs. Many of the goals targeted by social accountability mechanisms already exist. They may be better viewed as legal rights to participation through the guarantee to citizen participation in public affairs under the Ugandan Constitution.

  13. Validation of Quench Simulation and Simulation of the TWIN Solenoid

    CERN Document Server

    Pots, Rosalinde Hendrika

    2015-01-01

    For the Future Circular Collider at CERN a multi-purpose detector is proposed. The 6T TWIN Solenoid, a very large magnet system with a stored energy of 53 GJ, is being designed. It is important to protect the magnet against quenches in the system. Therefore several existing quench protection systems are evaluated and simulations have be performed on quenches in the TWIN Solenoid. The simulations on quenches in the TWIN Solenoid have been performed with promising results; the hotspot temperatures do not exceed 120 K and layer to layer voltages stay below 500 V. Adding quench heaters to the system might improve the quench protection system further.

  14. Using a NIATx Based Local Learning Collaborative for Performance Improvement

    Science.gov (United States)

    Roosa, Mathew; Scripa, Joseph S.; Zastowny, Thomas R.; Ford, James H., II

    2011-01-01

    Local governments play an important role in improving substance abuse and mental health services. The structure of the local learning collaborative requires careful attention to old relationships and challenges local governmental leaders to help move participants from a competitive to collaborative environment. This study describes one county's…

  15. Energizing Local Values For Tourism Services Improvement

    Directory of Open Access Journals (Sweden)

    Budi Purnomo

    2012-06-01

    Full Text Available People in most cultures would probably agree that politeness is needed during their interaction. However there may be differing opinions as to when they should be polite. In tourism industry, tourism service providers’ act as hosts and tourists act as guests. Typically hosts will try to act politely and use appropriate politeness norms when serving guests to ensure their satisfaction. The research findings show that the tourism service providers in Central Java use various unggah-ungguh ‘politeness norms’ when serving English speaking tourists and Indonesian speaking tourists. Besides that, there are some violations made by the tourism service providers in using unggah-ungguh ‘politeness norms’. The research findings also show that there are similar and different perspectives on unggah-ungguh ‘politeness norms’ between English speaking tourists with Western culture backgrounds and Indonesian speaking tourists with Indonesian culture backgrounds towards the politeness norms used by the tourism service providers in Central Java. The findings imply the needs of energizing unggah-ungguh ‘politeness norms’ which is discovered from well known noble Javanese values used by the tourism service providers for tourism service improvement.

  16. Quenching ofp-Cyanophenylalanine Fluorescence by Various Anions.

    Science.gov (United States)

    Pazos, Ileana M; Roesch, Rachel M; Gai, Feng

    2013-03-20

    To expand the spectroscopic utility of the non-natural amino acid p -cyanophenylalanine (Phe CN ), we examine the quenching efficiencies of a series of commonly encountered anions toward its fluorescence. We find that iodide exhibits an unusually large Stern-Volmer quenching constant, making it a convenient choice in Phe CN fluorescence quenching studies. Indeed, using the villin headpiece subdomain as a testbed we demonstrate that iodide quenching of Phe CN fluorescence offers a convenient means to reveal protein conformational heterogeneity. Furthermore, we show that the amino group of Phe CN strongly quenches its fluorescence, suggesting that Phe CN could be used as a local pH sensor.

  17. Effect of tree-level and mean-field improvement on the light-hadron spectrum in quenched QCD

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    We compute the light-hadron mass spectrum at β=5.7 using the O(a)-improved Sheikholeslami-Wohlert fermion action with two choices of the clover coefficient: the classical value c=1 and a mean-field or tadpole-improved estimate c=1.57. We compare our results with those of the GF11 Collaboration who use the Wilson fermion action (c=0). We find that changing c from zero to 1 and 1.57 leads to significant differences in the masses of the chirally extrapolated and strange pseudoscalar and vector mesons, the nucleon, the Δ, and also in the Edinburgh plot. A number of other quantities, for example, m V 2 -m P 2 , J, am K /am ρ , and am K * /am ρ do not appear to change significantly. We also investigate the effect of changing the lattice volume from approximately (2 fm) 3 to (2.6 fm) 3 . We find that the meson masses are consistent to within one standard deviation and baryon masses are consistent to within two standard deviations. copyright 1997 The American Physical Society

  18. Towards Improving Local Government Administration on the Rural ...

    African Journals Online (AJOL)

    One of the basic objectives of establishing local governments in Nigeria is to bring about development and improvement in the standard of living of the people at the local level. Though many calls have been made on the issue of decentralization of authority at this level, the fact remains that most of the activities of this arm of ...

  19. What is an integrable quench?

    Directory of Open Access Journals (Sweden)

    Lorenzo Piroli

    2017-12-01

    Full Text Available Inspired by classical results in integrable boundary quantum field theory, we propose a definition of integrable initial states for quantum quenches in lattice models. They are defined as the states which are annihilated by all local conserved charges that are odd under space reflection. We show that this class includes the states which can be related to integrable boundary conditions in an appropriate rotated channel, in loose analogy with the picture in quantum field theory. Furthermore, we provide an efficient method to test integrability of given initial states. We revisit the recent literature of global quenches in several models and show that, in all of the cases where closed-form analytical results could be obtained, the initial state is integrable according to our definition. In the prototypical example of the XXZ spin-s chains we show that integrable states include two-site product states but also larger families of matrix product states with arbitrary bond dimension. We argue that our results could be practically useful for the study of quantum quenches in generic integrable models.

  20. What is an integrable quench?

    Science.gov (United States)

    Piroli, Lorenzo; Pozsgay, Balázs; Vernier, Eric

    2017-12-01

    Inspired by classical results in integrable boundary quantum field theory, we propose a definition of integrable initial states for quantum quenches in lattice models. They are defined as the states which are annihilated by all local conserved charges that are odd under space reflection. We show that this class includes the states which can be related to integrable boundary conditions in an appropriate rotated channel, in loose analogy with the picture in quantum field theory. Furthermore, we provide an efficient method to test integrability of given initial states. We revisit the recent literature of global quenches in several models and show that, in all of the cases where closed-form analytical results could be obtained, the initial state is integrable according to our definition. In the prototypical example of the XXZ spin-s chains we show that integrable states include two-site product states but also larger families of matrix product states with arbitrary bond dimension. We argue that our results could be practically useful for the study of quantum quenches in generic integrable models.

  1. Using a NIATx based local learning collaborative for performance improvement

    Science.gov (United States)

    Roosa, Mathew; Scripa, Joseph S.; Zastowny, Thomas R.; Ford, James H.

    2012-01-01

    Local governments play an important role in improving substance abuse and mental health services. The structure of the local learning collaborative requires careful attention to old relationships and challenges local governmental leaders to help move participants from a competitive to collaborative environment. This study describes one county’s experience applying the NIATx process improvement model via a local learning collaborative. Local substance abuse and mental health agencies participated in two local learning collaboratives designed to improve client retention in substance abuse treatment and client access to mental health services. Results of changes implemented at the provider level on access and retention are outlined. The process of implementing evidence-based practices by using the Plan-Do-Study-Act rapid-cycle change is a powerful combination for change at the local level. Key lessons include: creating a clear plan and shared vision, recognizing that one size does not fit all, using data can help fuel participant engagement, a long collaborative may benefit from breaking it into smaller segments, and paying providers to offset costs of participation enhances their engagement. The experience gained in Onondaga County, New York, offers insights that serve as a foundation for using the local learning collaborative in other community-based organizations. PMID:21371751

  2. Using a NIATx based local learning collaborative for performance improvement.

    Science.gov (United States)

    Roosa, Mathew; Scripa, Joseph S; Zastowny, Thomas R; Ford, James H

    2011-11-01

    Local governments play an important role in improving substance abuse and mental health services. The structure of the local learning collaborative requires careful attention to old relationships and challenges local governmental leaders to help move participants from a competitive to collaborative environment. This study describes one county's experience applying the NIATx process improvement model via a local learning collaborative. Local substance abuse and mental health agencies participated in two local learning collaboratives designed to improve client retention in substance abuse treatment and client access to mental health services. Results of changes implemented at the provider level on access and retention are outlined. The process of implementing evidence-based practices by using the Plan-Do-Study-Act rapid-cycle change is a powerful combination for change at the local level. Key lessons include: creating a clear plan and shared vision, recognizing that one size does not fit all, using data can help fuel participant engagement, a long collaborative may benefit from breaking it into smaller segments, and paying providers to offset costs of participation enhances their engagement. The experience gained in Onondaga County, New York, offers insights that serve as a foundation for using the local learning collaborative in other community-based organizations. Copyright © 2011 Elsevier Ltd. All rights reserved.

  3. Adjuvant radiation for vulvar carcinoma: improved local control

    International Nuclear Information System (INIS)

    Faul, Clare M.; Mirmow, Dwight; Huang Qingshon; Gerszten, Kristina; Day, Roger; Jones, Mirka W.

    1997-01-01

    Purpose: Local recurrence is a significant problem following primary surgery for advanced vulva carcinoma. The objectives of this study were to evaluate the impact of adjuvant vulvar radiation on local control in high risk patients and the impact of local recurrence on overall survival. Methods and Materials: From 1980-1994, 62 patients with invasive vulva carcinoma and either positive or close (less 8 mm) margins of excision were retrospectively studied. Thirty-one patients were treated with adjuvant radiation therapy to the vulva and 31 patients were observed after surgery. Kaplan-Meier estimates and the Cox proportional hazard regression model were used to evaluate the effect of adjuvant radiation therapy on local recurrence and overall survival. Independent prognostic factors for local recurrence and survival were also assessed. Results: Local recurrence occurred in 58% of observed patients and 16% in patients treated with adjuvant radiation therapy. Adjuvant radiation therapy significantly reduced local recurrence rates in both the close margin and positive margin groups (p = 0.036, p = 0.0048). On both univariate and multivariate analysis adjuvant radiation and margins of excision were significant prognostic predictors for local control. Significant determinants of actuarial survival included International Federation of Gynecologists and Obstetricians (FIGO) stage, percentage of pathologically positive inguinal nodes and margins of excision. The positive margin observed group had a significantly poorer actuarial 5 year survival than the other groups (p = 0.0016) and adjuvant radiation significantly improved survival for this group. The 2 year actuarial survival after developing local recurrence was 25%. Local recurrence was a significant predictor for death from vulva carcinoma (risk ratio 3.54). Conclusion: Local recurrence is a common occurrence in high risk patients. In this study adjuvant radiation therapy significantly reduced local recurrence rates and

  4. Facile single-step ammonia heat-treatment and quenching process for the synthesis of improved Pt/N-graphene catalysts

    Science.gov (United States)

    Xiong, Bin; Zhou, Yingke; O'Hayre, Ryan; Shao, Zongping

    2013-02-01

    In this work, we present a facile route to prepare electrocatalysts for methanol oxidation. The catalyst synthesis route involves the simultaneous reduction and nitrogen doping of graphene oxide (GO) along with the reduction of H2PtCl6 to Pt by a facile ammonia gas heat-treatment and quenching process. The resulting catalysts are characterized by X-ray diffraction, transmission electron microscopy, and X-ray photoelectron spectroscopy while their electrocatalytic activity toward the oxidation of methanol is evaluated by cyclic voltammetry. The obtained Pt/graphene composites consist of crystalline Pt nanoparticles in the range of 1-4 nm which are well-dispersed on the N-doped graphene sheets. The best Pt/N-graphene catalyst composite is obtained after a 5 min ammonia treatment at 800 °C followed by rapid ammonia gas quenching at room temperature. This catalyst demonstrates superior catalytic activity for methanol electro-oxidation, with a peak current density of 0.218 A mgPt-1, which is about five times higher than an undoped (hydrogen treated and quenched) Pt/graphene control catalyst. The excellent electrocatalytic performance of the ammonia quenched catalyst is attributed to the nitrogenous functional groups and dopants in the graphene sheets that are formed during the facile quenching process in ammonia.

  5. Analysis of the quench propagation along Nb3Sn Rutherford cables with the THELMA code. Part II: application to the quench longitudinal propagation

    CERN Document Server

    Manfreda, G.; Bajas, H.; Perez, J.C.

    2016-01-01

    To improve the technology of the new generation of accelerator magnets, prototypes are being manufactured and tested in several laboratories. In parallel, many numerical analyses are being carried out to predict the magnets behaviour and interpret the experimental results. This paper focuses on the quench propagation velocity, which is a crucial parameter as regards the energy dissipation along the magnet conductor. The THELMA code, originally developed for cable-in-conduit conductors for fusion magnets, has been used to study such quench propagation. To this purpose, new code modules have been added to describe the Rutherford cable geometry, the material non-linear thermal properties and to describe the thermal conduction problem in transient regime. THELMA can describe the Rutherford cable at the strand level, modelling both the electrical and thermal contact resistances between strands and enabling the analysis of the effects of local hot spots and quench heaters. This paper describes the model application...

  6. The improvement of PWR(OPR-1000) Local Control Pannel

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Joo-Youl; Kim, Min-Soo; Kim, Kyung-Min; Lee, Jun-Kou [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The malfunction of feature in NPP could be occurred by physical aging, electrical false signal and natural disaster. The first recognition of malfunction is almost done by alarm system. Due to the importance of alarm system, design basis of alarm system is described in FSAR 18.1.4.20(alarm system design review). Operators can recognize malfunction of feature and importance of alarm in short distance. The sound of alarm is also changed depending on frequency so it contributes recognition of alarm. This system is not helpful in recognition of alarm for filed operators. In this study, the way that FSAR(priority of alarm and color indication) is also applied on local control is suggested. The alarm sound considering field situation, alarm name, status indication in circuit breaker are suggested to improve overall local control panel. These can contribute to safety operation. This paper is made from improvement items of local control panel in the sight of field operator. The research of local panel is necessary to apply these improvements and the collaboration of related department is also needed. In this study, The alarm sound considering field situation, alarm name, status indication in circuit breaker are suggested to improve overall local control panel based on Hanul Unit 6. If the improvement is applied, the qualitative effect of safe operation will be increased, and fatigue of work stress will be lower.

  7. TASK 2: QUENCH ZONE SIMULATION

    Energy Technology Data Exchange (ETDEWEB)

    Fusselman, Steve

    2015-09-30

    Aerojet Rocketdyne (AR) has developed an innovative gasifier concept incorporating advanced technologies in ultra-dense phase dry feed system, rapid mix injector, and advanced component cooling to significantly improve gasifier performance, life, and cost compared to commercially available state-of-the-art systems. A key feature of the AR gasifier design is the transition from the gasifier outlet into the quench zone, where the raw syngas is cooled to ~ 400°C by injection and vaporization of atomized water. Earlier pilot plant testing revealed a propensity for the original gasifier outlet design to accumulate slag in the outlet, leading to erratic syngas flow from the outlet. Subsequent design modifications successfully resolved this issue in the pilot plant gasifier. In order to gain greater insight into the physical phenomena occurring within this zone, AR developed a cold flow simulation apparatus with Coanda Research & Development with a high degree of similitude to hot fire conditions with the pilot scale gasifier design, and capable of accommodating a scaled-down quench zone for a demonstration-scale gasifier. The objective of this task was to validate similitude of the cold flow simulation model by comparison of pilot-scale outlet design performance, and to assess demonstration scale gasifier design feasibility from testing of a scaled-down outlet design. Test results did exhibit a strong correspondence with the two pilot scale outlet designs, indicating credible similitude for the cold flow simulation device. Testing of the scaled-down outlet revealed important considerations in the design and operation of the demonstration scale gasifier, in particular pertaining to the relative momentum between the downcoming raw syngas and the sprayed quench water and associated impacts on flow patterns within the quench zone. This report describes key findings from the test program, including assessment of pilot plant configuration simulations relative to actual

  8. Fiber optic quench detection via optimized Rayleigh Scattering in high-field YBCO accelerator magnets

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, Gene [North Carolina State Univ., Raleigh, NC (United States)

    2016-02-17

    Yttrium barium copper oxide (YBCO) coated conductors are known for their ability to operate in the superconducting state at relatively high temperatures, even above the boiling point of liquid nitrogen (77 K). When these same conductors are operated at lower temperatures, they are able to operate in much higher magnetic fields than traditional superconductors like NiTi or Nb3Sn. Thus, YBCO superconducting magnets are one of the primary options for generating the high magnetic fields needed for future high energy physics devices. Due to slow quench propagation, quench detection remains one of the primary limitations to YBCO magnets. Fiber optic sensing, based upon Rayleigh scattering, has the potential for spatial resolution approaching the wavelength of light, or very fast temporal resolution at low spatial resolution, and a continuum of combinations in between. This project has studied, theoretically and experimentally, YBCO magnets and Rayleigh scattering quench detection systems to demonstrate feasibility of the systems for YBCO quench protection systems. Under this grant an experimentally validated 3D quench propagation model was used to accurately define the acceptable range of spatial and temporal resolutions for effective quench detection in YBCO magnets and to evaluate present-day and potentially improved YBCO conductors. The data volume and speed requirements for quench detection via Rayleigh scattering required the development of a high performance fiber optic based quench detection/data acquisition system and its integration with an existing voltage tap/thermo-couple based system. In this project, optical fibers are tightly co-wound into YBCO magnet coils, with the fiber on top of the conductor as turn-to-turn insulation. Local changes in the temperature or strain of the conductor are sensed by the optical fiber, which is in close thermal and mechanical contact with the conductor. Intrinsic imperfections in the fiber reflect Rayleigh

  9. Improved Grid-Scan Localization Algorithm for Wireless Sensor Networks

    OpenAIRE

    Nallanthighal, Raghava Srinivasa; Chinta, Veeranjaneyulu

    2014-01-01

    Localization is a fundamental and crucial service for various applications in wireless sensor networks (WSNs). In this paper an improved grid-scan localization algorithm has been proposed. In the proposed algorithm, information about 1-hop, 2-hop, and farther neighboring anchors has been collected that estimates the region using 1-hop anchors. Then, this estimated region is divided into a grid array, finding valid grids using 1-hop and 2-hop anchors information. In addition to that the farthe...

  10. Improving IMES Localization Accuracy by Integrating Dead Reckoning Information.

    Science.gov (United States)

    Fujii, Kenjiro; Arie, Hiroaki; Wang, Wei; Kaneko, Yuto; Sakamoto, Yoshihiro; Schmitz, Alexander; Sugano, Shigeki

    2016-01-27

    Indoor positioning remains an open problem, because it is difficult to achieve satisfactory accuracy within an indoor environment using current radio-based localization technology. In this study, we investigate the use of Indoor Messaging System (IMES) radio for high-accuracy indoor positioning. A hybrid positioning method combining IMES radio strength information and pedestrian dead reckoning information is proposed in order to improve IMES localization accuracy. For understanding the carrier noise ratio versus distance relation for IMES radio, the signal propagation of IMES radio is modeled and identified. Then, trilateration and extended Kalman filtering methods using the radio propagation model are developed for position estimation. These methods are evaluated through robot localization and pedestrian localization experiments. The experimental results show that the proposed hybrid positioning method achieved average estimation errors of 217 and 1846 mm in robot localization and pedestrian localization, respectively. In addition, in order to examine the reason for the positioning accuracy of pedestrian localization being much lower than that of robot localization, the influence of the human body on the radio propagation is experimentally evaluated. The result suggests that the influence of the human body can be modeled.

  11. Improving IMES Localization Accuracy by Integrating Dead Reckoning Information

    Directory of Open Access Journals (Sweden)

    Kenjiro Fujii

    2016-01-01

    Full Text Available Indoor positioning remains an open problem, because it is difficult to achieve satisfactory accuracy within an indoor environment using current radio-based localization technology. In this study, we investigate the use of Indoor Messaging System (IMES radio for high-accuracy indoor positioning. A hybrid positioning method combining IMES radio strength information and pedestrian dead reckoning information is proposed in order to improve IMES localization accuracy. For understanding the carrier noise ratio versus distance relation for IMES radio, the signal propagation of IMES radio is modeled and identified. Then, trilateration and extended Kalman filtering methods using the radio propagation model are developed for position estimation. These methods are evaluated through robot localization and pedestrian localization experiments. The experimental results show that the proposed hybrid positioning method achieved average estimation errors of 217 and 1846 mm in robot localization and pedestrian localization, respectively. In addition, in order to examine the reason for the positioning accuracy of pedestrian localization being much lower than that of robot localization, the influence of the human body on the radio propagation is experimentally evaluated. The result suggests that the influence of the human body can be modeled.

  12. screening and improvement of local isolates of aspergillus niger

    African Journals Online (AJOL)

    DR. AMINU

    ABSTRACT. The study involved the screening of fourteen isolates of Aspergillus niger for citric acid production from glucose. The study was aimed at screening and improving local strains of Aspergillus niger with potential for citric acid production. All the isolates screened produced varying amounts of citric acid, the highest ...

  13. Nutritional quality and utilization of local and improved cowpea ...

    African Journals Online (AJOL)

    Cowpeas are grown for their leaves and grains both of which are used as relish or side dishes together with the staple food. Little information is available on the nutritional quality of local and improved cowpea varieties grown in Tanzania as well as the recipes in which they are ingredients. This study was done to investigate ...

  14. Improving farmer adaptive capacity by integrating local and ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-04-22

    Improving farmer adaptive capacity by integrating local and indigenous knowledge in climate forecasting. April 22, 2016. Image. Despite the availability of more reliable forecasts from meteorological services in Kenya, farmers seldom use them for farm level decision-making. This case study discusses how downscaled ...

  15. Economics of Improved and Local Varieties of Cassava among ...

    African Journals Online (AJOL)

    This study was based on the economics of improved and local cassava varieties and its welfare effect on producing farmers in Oyo State, Nigeria. A three-stage sampling procedure was used to collect information from 144 cassava farmers in the study area. However, only 120 pieces of questionnaires were retrieved and ...

  16. Seed-borne mycoflora of local and improved wheat ( Triticum ...

    African Journals Online (AJOL)

    Three varieties each of local and improved wheat (Triticum sativum) cultivars were investigated for seed-borne pathogenic mycoflora using the plate technique and laid on completely randomized design. A total 99 fungal isolate grouped into five fungal species namely; Rhizopus nigricans, Mucor spp, Penillium jenseni, ...

  17. Ebola Crisis: Improving Science-Based Communication and Local ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ebola Crisis: Improving Science-Based Communication and Local Journalism in Emergency and Post-outbreak Periods. The World Federation of Science Journalists (WFSJ) is leading ... Nutrition, health policy, and ethics in the age of public-private partnerships. How are public health actors working with the food and drinks ...

  18. Adoption of improved rice varieties by farmers in Bende local ...

    African Journals Online (AJOL)

    The study investigated the adoption of improved rice varieties by farmers in Bende Local Government Area, Abia State, Nigeria. A multi-stage random sampling technique was used to select a total of 120 rice farmers. Descriptive statistics and tobit regression model were employed to analyze the data. Results showed that ...

  19. Characterizing Water Quenching Systems with a Quench Probe

    Science.gov (United States)

    Ferguson, B. Lynn; Li, Zhichao; Freborg, Andrew M.

    2014-12-01

    Quench probes have been used effectively to characterize the quality of quenchants for many years. For this purpose, a variety of commercial probes, as well as the necessary data acquisition system for determining the time-temperature data for a set of standardized test conditions, are available for purchase. The type of information obtained from such probes provides a good basis for comparing media, characterizing general cooling capabilities, and checking media condition over time. However, these data do not adequately characterize the actual production quenching process in terms of heat transfer behavior in many cases, especially when high temperature gradients are present. Faced with the need to characterize water quenching practices, including conventional and intensive practices, a quench probe was developed. This paper describes that probe, the data collection system, the data gathered for both intensive quenching and conventional water quenching, and the heat transfer coefficients determined for these processes. Process sensitivities are investigated and highlight some intricacies of quenching.

  20. Calculating Quenching Weights

    CERN Document Server

    Salgado, C A; Salgado, Carlos A.; Wiedemann, Urs Achim

    2003-01-01

    We calculate the probability (``quenching weight'') that a hard parton radiates an additional energy fraction due to scattering in spatially extended QCD matter. This study is based on an exact treatment of finite in-medium path length, it includes the case of a dynamically expanding medium, and it extends to the angular dependence of the medium-induced gluon radiation pattern. All calculations are done in the multiple soft scattering approximation (Baier-Dokshitzer-Mueller-Peign\\'e-Schiff--Zakharov ``BDMPS-Z''-formalism) and in the single hard scattering approximation (N=1 opacity approximation). By comparison, we establish a simple relation between transport coefficient, Debye screening mass and opacity, for which both approximations lead to comparable results. Together with this paper, a CPU-inexpensive numerical subroutine for calculating quenching weights is provided electronically. To illustrate its applications, we discuss the suppression of hadronic transverse momentum spectra in nucleus-nucleus colli...

  1. Improved local lattice Monte Carlo simulation for charged systems

    Science.gov (United States)

    Jiang, Jian; Wang, Zhen-Gang

    2018-03-01

    Maggs and Rossetto [Phys. Rev. Lett. 88, 196402 (2002)] proposed a local lattice Monte Carlo algorithm for simulating charged systems based on Gauss's law, which scales with the particle number N as O(N). This method includes two degrees of freedom: the configuration of the mobile charged particles and the electric field. In this work, we consider two important issues in the implementation of the method, the acceptance rate of configurational change (particle move) and the ergodicity in the phase space sampled by the electric field. We propose a simple method to improve the acceptance rate of particle moves based on the superposition principle for electric field. Furthermore, we introduce an additional updating step for the field, named "open-circuit update," to ensure that the system is fully ergodic under periodic boundary conditions. We apply this improved local Monte Carlo simulation to an electrolyte solution confined between two low dielectric plates. The results show excellent agreement with previous theoretical work.

  2. Improving conservation outcomes with insights from local experts and bureaucracies.

    Science.gov (United States)

    Haenn, Nora; Schmook, Birgit; Reyes, Yol; Calmé, Sophie

    2014-08-01

    We describe conservation built on local expertise such that it constitutes a hybrid form of traditional and bureaucratic knowledge. Researchers regularly ask how local knowledge might be applied to programs linked to protected areas. By examining the production of conservation knowledge in southern Mexico, we assert local expertise is already central to conservation. However, bureaucratic norms and social identity differences between lay experts and conservation practitioners prevent the public valuing of traditional knowledge. We make this point by contrasting 2 examples. The first is a master's thesis survey of local experts regarding the biology of the King Vulture (Sarcoramphus papa) in which data collection took place in communities adjacent to the Calakmul Biosphere Reserve. The second is a workshop sponsored by the same reserve that instructed farmers on how to monitor endangered species, including the King Vulture. In both examples, conservation knowledge would not have existed without traditional knowledge. In both examples, this traditional knowledge is absent from scientific reporting. On the basis of these findings, we suggest conservation outcomes may be improved by recognizing the knowledge contributions local experts already make to conservation programming. © 2014 Society for Conservation Biology.

  3. QUESTION OF IMPROVEMENT OF BUDGET CONTROL AT THE LOCAL LEVEL

    Directory of Open Access Journals (Sweden)

    Oleg Vatslavskyi

    2016-11-01

    Full Text Available The aim is to analyse the current practice of budgetary control to develop its areas of improvement at the local level. The subject of the research is theoretical and methodological principles of functioning of budgetary control at the local level. The methodological basis of the study comprises research approaches, general theoretical principles of scientific knowledge, system of methods and techniques. The paper clarifies the nature of budgetary control at the local level. The main bodies that implement budget control, namely the State Audit Office, the Accounting Chamber, the State Treasury, the State Fiscal Service, financial and management departments are singled out. It is found that the leading part among all of the special budgetary control bodies in the rational and efficient use of local financial resources is performed by the State Audit Office. Analysis of the State Audit Office in three regions of Ukraine for the period 2013-2015 has been carried out. We distinguish two main types of violations that the State Audit Service reveals during its work at the local level: 1 shortfall in the financial resources of public enterprises, institutions and organizations; 2 violations that lead to illegal, non-target costs and shortages. It is proved that the efficiency of budgetary control is low. The paper states basic problems of budget control at the local level, namely, low income funds and reimbursements from violations revealed by regulatory agencies; insufficient work with the public to explain the problems of budget control and eliminate violations in the public sector; lack of a consolidated legal act, which would have regulated all the major components of budgetary control; insufficient use of controlling and auditing methods aimed at determining the effectiveness of budget funds; low preventive function on the part of budget control bodies. We offer ways to improve budget control at the local level through: standardization system of

  4. An improved local remeshing algorithm for moving boundary problems

    Directory of Open Access Journals (Sweden)

    Jianjing Zheng

    2016-01-01

    Full Text Available Three issues are tackled in this study to improve the robustness of local remeshing techniques. Firstly, the local remeshing region (hereafter referred to as ‘hole’ is initialized by removing low-quality elements and then continuously expanded until a certain element quality is reached after remeshing. The effect of the number of the expansion cycle on the hole size and element quality after remeshing is experimentally analyzed. Secondly, the grid sources for element size control are attached to moving bodies and will move along with their host bodies to ensure reasonable grid resolution inside the hole. Thirdly, the boundary recovery procedure of a Delaunay grid generation approach is enhanced by a new grid topology transformation technique (namely shell transformation so that the new grid created inside the hole is therefore free of elements of extremely deformed/skewed shape, whilst also respecting the hole boundary. The proposed local remeshing algorithm has been integrated with an in-house unstructured grid-based simulation system for solving moving boundary problems. The robustness and accuracy of the developed local remeshing technique are successfully demonstrated via industry-scale applications for complex flow simulations.

  5. Influence of quench rates on the properties of rapidly solidified ...

    Indian Academy of Sciences (India)

    ... techniques. The crystallization, magnetic, mechanical and corrosion behaviour were studied for the prepared materials as a function of quenching rate from liquid to the solid state. Higher quench rates produced a more amorphous structure exhibiting superior soft magnetic properties with improved corrosion resistance.

  6. The G-BHQ synergistic effect: Improved double quenching molecular beacons based on guanine and Black Hole Quencher for sensitive simultaneous detection of two DNAs.

    Science.gov (United States)

    Xiang, Dongshan; Li, Fengquan; Wu, Chenyi; Shi, Boan; Zhai, Kun

    2017-11-01

    We designed two double quenching molecular beacons (MBs) with simple structure based on guanine (G base) and Black Hole Quencher (BHQ), and developed a new analytical method for sensitive simultaneous detection of two DNAs by synchronous fluorescence analysis. In this analytical method, carboxyl fluorescein (FAM) and tetramethyl-6-carboxyrhodamine (TAMRA) were respectively selected as fluorophore of two MBs, Black Hole Quencher 1 (BHQ-1) and Black Hole Quencher 2 (BHQ-2) were respectively selected as organic quencher, and three continuous nucleotides with G base were connected to organic quencher (BHQ-1 and BHQ-2). In the presence of target DNAs, the two MBs hybridize with the corresponding target DNAs, the fluorophores are separated from organic quenchers and G bases, leading to recovery of fluorescence of FAM and TAMRA. Under a certain conditions, the fluorescence intensities of FAM and TAMRA all exhibited good linear dependence on their concentration of target DNAs (T1 and T2) in the range from 4 × 10 -10 to 4 × 10 -8 molL -1 (M). The detection limit (3σ, n = 13) of T1 was 3 × 10 -10 M and that of T2 was 2×10 -10 M, respectively. Compared with the existing analysis methods for multiplex DNA with MBs, this proposed method based on double quenching MBs is not only low fluorescence background, short analytical time and low detection cost, but also easy synthesis and good stability of MB probes. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Fast quench reactor method

    Science.gov (United States)

    Detering, B.A.; Donaldson, A.D.; Fincke, J.R.; Kong, P.C.; Berry, R.A.

    1999-08-10

    A fast quench reaction includes a reactor chamber having a high temperature heating means such as a plasma torch at its inlet and a means of rapidly expanding a reactant stream, such as a restrictive convergent-divergent nozzle at its outlet end. Metal halide reactants are injected into the reactor chamber. Reducing gas is added at different stages in the process to form a desired end product and prevent back reactions. The resulting heated gaseous stream is then rapidly cooled by expansion of the gaseous stream. 8 figs.

  8. Assessing local resources and culture before instituting quality improvement projects.

    Science.gov (United States)

    Hawkins, C Matthew

    2014-12-01

    The planning phases of quality improvement projects are commonly overlooked. Disorganized planning and implementation can escalate chaos, intensify resistance to change, and increase the likelihood of failure. Two important steps in the planning phase are (1) assessing local resources available to aid in the quality improvement project and (2) evaluating the culture in which the desired change is to be implemented. Assessing local resources includes identifying and engaging key stakeholders and evaluating if appropriate expertise is available for the scope of the project. This process also involves engaging informaticists and gathering available IT tools to plan and automate (to the extent possible) the data-gathering, analysis, and feedback steps. Culture in a department is influenced by the ability and willingness to manage resistance to change, build consensus, span boundaries between stakeholders, and become a learning organization. Allotting appropriate time to perform these preparatory steps will increase the odds of successfully performing a quality improvement project and implementing change. Copyright © 2014 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  9. Quench observation using quench antennas on RHIC IR quadrupole magnets

    International Nuclear Information System (INIS)

    Ogitsu, T.; Terashima, A.; Tsuchiya, K.; Ganetis, G.; Muratore, J.; Wanderer, P.

    1995-01-01

    Quench observation using quench antennas is now being performed routinely on RHIC dipole and quadrupole magnets. Recently, a quench antenna was used on a RHIC IR magnet which is heavily instrumented with voltage taps. It was confirmed that the signals detected in the antenna coils do not contradict the voltage tap signals. The antenna also detects a sign of mechanical disturbance which could be related to a training quench. This paper summarizes signals detected in the antenna and discusses possible causes of these signals

  10. Distributed SLAM Using Improved Particle Filter for Mobile Robot Localization

    Directory of Open Access Journals (Sweden)

    Fujun Pei

    2014-01-01

    Full Text Available The distributed SLAM system has a similar estimation performance and requires only one-fifth of the computation time compared with centralized particle filter. However, particle impoverishment is inevitably because of the random particles prediction and resampling applied in generic particle filter, especially in SLAM problem that involves a large number of dimensions. In this paper, particle filter use in distributed SLAM was improved in two aspects. First, we improved the important function of the local filters in particle filter. The adaptive values were used to replace a set of constants in the computational process of importance function, which improved the robustness of the particle filter. Second, an information fusion method was proposed by mixing the innovation method and the number of effective particles method, which combined the advantages of these two methods. And this paper extends the previously known convergence results for particle filter to prove that improved particle filter converges to the optimal filter in mean square as the number of particles goes to infinity. The experiment results show that the proposed algorithm improved the virtue of the DPF-SLAM system in isolate faults and enabled the system to have a better tolerance and robustness.

  11. Quenching of p-cyanophenylalanine fluorescence by various anions

    Science.gov (United States)

    Pazos, Ileana M.; Roesch, Rachel M.; Gai, Feng

    2013-03-01

    To expand the spectroscopic utility of the non-natural amino acid p-cyanophenylalanine (PheCN), we examine the quenching efficiencies of a series of commonly encountered anions toward its fluorescence. We find that iodide exhibits an unusually large Stern-Volmer quenching constant, making it a convenient choice in PheCN fluorescence quenching studies. Indeed, using the villin headpiece subdomain as a testbed we demonstrate that iodide quenching of PheCN fluorescence offers a convenient means to reveal protein conformational heterogeneity. Furthermore, we show that the amino group of PheCN strongly quenches its fluorescence, suggesting that PheCN could be used as a local pH sensor.

  12. Improving Indoor Localization Using Bluetooth Low Energy Beacons

    Directory of Open Access Journals (Sweden)

    Pavel Kriz

    2016-01-01

    Full Text Available The paper describes basic principles of a radio-based indoor localization and focuses on the improvement of its results with the aid of a new Bluetooth Low Energy technology. The advantage of this technology lies in its support by contemporary mobile devices, especially by smartphones and tablets. We have implemented a distributed system for collecting radio fingerprints by mobile devices with the Android operating system. This system enables volunteers to create radio-maps and update them continuously. New Bluetooth Low Energy transmitters (Apple uses its “iBeacon” brand name for these devices have been installed on the floor of the building in addition to existing WiFi access points. The localization of stationary objects based on WiFi, Bluetooth Low Energy, and their combination has been evaluated using the data measured during the experiment in the building. Several configurations of the transmitters’ arrangement, several ways of combination of the data from both technologies, and other parameters influencing the accuracy of the stationary localization have been tested.

  13. Deciphering jet quenching with JEWEL

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    In heavy ion collisions jets arising from the fragmentation of hard quarks and gluons experience strong modifications due to final state re-scattering. This so-called jet quenching is related to the emergence of collectivity and equilibration in QCD. I will give an introduction to jet quenching and its modeling in JEWEL, a Monte Carlo implementation of a dynamical model for jet quenching. I will then discuss examples highlighting how JEWEL can be used to elucidate the physical mechanisms relevant for jet quenching.  

  14. Estimation of the FRF Through the Improved Local Bandwidth Selection in the Local Polynomial Method

    DEFF Research Database (Denmark)

    Thummala, Prasanth; Schoukens, Johan

    2012-01-01

    This paper presents a nonparametric method to measure an improved frequency response function (FRF) of a linear dynamic system excited by a random input. Recently, the local polynomial method (LPM) has been proposed as a technique to reduce the leakage errors on FRF measurements. The noise sensit...... are combined in a single-point estimate, to get lower noise sensitivity by increasing the smoothening of the original LPM, without any user interaction. The balance between noise reduction and bias error will be automatically retrieved....

  15. Minimum Quench Energy and Early Quench Development in NbTi Superconducting Strands

    CERN Document Server

    Breschi, M; Boselli, M; Bottura, Luca; Devred, Arnaud; Ribani, P L; Trillaud, F

    2007-01-01

    The stability of superconducting wires is a crucial task in the design of safe and reliable superconducting magnets. These magnets are prone to premature quenches due to local releases of energy. In order to simulate these energy disturbances, various heater technologies have been developed, such as coated tips, graphite pastes, and inductive coils. The experiments studied in the present work have been performed using a single-mode diode laser with an optical fiber to illuminate the superconducting strand surface. Minimum quench energies and voltage traces at different magnetic flux densities and transport currents have been measured on an LHC-type, Cu/NbTi wire bathed in pool boiling helium I. This paper deals with the numerical analysis of the experimental data. In particular, a coupled electromagnetic and thermal model has been developed to study quench development and propagation, focusing on the influence of heat exchange with liquid helium.

  16. Environmental Quenching of Low-Mass Field Galaxies

    Science.gov (United States)

    Fillingham, Sean P.; Cooper, Michael C.; Boylan-Kolchin, Michael; Bullock, James S.; Garrison-Kimmel, Shea; Wheeler, Coral

    2018-04-01

    In the local Universe, there is a strong division in the star-forming properties of low-mass galaxies, with star formation largely ubiquitous amongst the field population while satellite systems are predominantly quenched. This dichotomy implies that environmental processes play the dominant role in suppressing star formation within this low-mass regime (M⋆ ˜ 105.5 - 8 M⊙). As shown by observations of the Local Volume, however, there is a non-negligible population of passive systems in the field, which challenges our understanding of quenching at low masses. By applying the satellite quenching models of Fillingham et al. (2015) to subhalo populations in the Exploring the Local Volume In Simulations (ELVIS) suite, we investigate the role of environmental processes in quenching star formation within the nearby field. Using model parameters that reproduce the satellite quenched fraction in the Local Group, we predict a quenched fraction - due solely to environmental effects - of ˜0.52 ± 0.26 within 1 feedback.

  17. Immune Modulation and Stereotactic Radiation: Improving Local and Abscopal Responses

    Directory of Open Access Journals (Sweden)

    Jing Zeng

    2013-01-01

    Full Text Available New and innovative treatment strategies for cancer patients in the fields of immunotherapy and radiotherapy are rapidly developing in parallel. Among the most promising preclinical treatment approaches is combining immunotherapy with radiotherapy where early data suggest synergistic effects in several tumor model systems. These studies demonstrate that radiation combined with immunotherapy can result in superior efficacy for local tumor control. More alluring is the emergence of data suggesting an equally profound systemic response also known as “abscopal” effects with the combination of radiation and certain immunotherapies. Studies addressing optimal radiation dose, fractionation, and modality to be used in combination with immunotherapy still require further exploration. However, recent anecdotal clinical reports combining stereotactic or hypofractionated radiation regimens with immunotherapy have resulted in dramatic sustained clinical responses, both local and abscopal. Technologic advances in clinical radiation therapy has made it possible to deliver hypofractionated regimens anywhere in the body using stereotactic radiation techniques, facilitating further clinical investigations. Thus, stereotactic radiation in combination with immunotherapy agents represents an exciting and potentially fruitful new space for improving cancer therapeutic responses.

  18. Discharge quenching circuit for counters

    International Nuclear Information System (INIS)

    Karasik, A.S.

    1982-01-01

    A circuit for quenching discharges in gas-discharge detectors with working voltage of 3-5 kV based on transistors operating in the avalanche mode is described. The quenching circuit consists of a coordinating emitter follower, amplifier-shaper for avalanche key cascade control which changes potential on the counter electrodes and a shaper of discharge quenching duration. The emitter follower is assembled according to a widely used flowsheet with two transistors. The circuit permits to obtain a rectangular quenching pulse with front of 100 ns and an amplitude of up to 3.2 kV at duration of 500 μm-8 ms. Application of the quenching circuit described permits to obtain countering characteristics with the slope less than or equal to 0.02%/V and plateau extent greater than or equal to 300 V [ru

  19. Strategies to improve local control of resected pancreas adenocarcinoma.

    Science.gov (United States)

    Sugarbaker, Paul H

    2017-03-01

    (NIPEC-LT) gemcitabine for 6 months postoperatively is suggested as a new treatment that has demonstrated decreases in local-regional failure and promises to more adequately target micrometastases in the peritoneal space, in the liver and lymph nodes. Pancreas cancer surgery should attempt to achieve negative margins of resection with the removal of at least 12 lymph nodes. Hyperthermic intraperitoneal gemcitabine can adequately eradicate malignant cells dislodged from the cancer specimen into the bed of the resection at high density and on distant peritoneal surfaces as peritoneal metastases. Long-term intraperitoneal gemcitabine may act on micrometastases in the liver through absorption into the portal vein blood and the lymph nodes as a result of gemcitabine absorption by subperitoneal lymphatic channels. The use of HIPEC and NIPEC-LT gemcitabine may improve local control of resected pancreas cancer. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Quantum quench with hard wall boundary conditions

    Science.gov (United States)

    Goldstein, Garry; Andrei, Natan

    2015-03-01

    In this work we present analysis of a quench for the Lieb Liniger gas contained in a large box with hard wall boundary conditions. We study the time average of local correlation functions. We show that both the quench action logic and the GGE are applicable. We show that the time average of the system corresponds to an eigenstate of the Lieb Liniger Hamiltonian. We show that this eigenstate is related to an eigenstate of a Lieb Liniger Hamiltonian with periodic boundary conditions on an interval of twice the length and with twice as many particles (a doubled system). We further show that local operators with support far away from the boundaries of the hard wall Lieb Liniger gas have the same expectation values as corresponding operators for the doubled system. We present an example of a quench where the Lieb Liniger gas is initially confined in several traps and then released into a bigger container, an approximate description of the Newton cradle experiment. This research was supported by NSF Grant DMR 1006684 and Rutgers CMT fellowship.

  1. Universality in fast quantum quenches

    Energy Technology Data Exchange (ETDEWEB)

    Das, Sumit R. [Department of Physics and Astronomy, University of Kentucky,505 Rose Street, Lexington, KY 40506 (United States); Galante, Damián A. [Department of Applied Mathematics, University of Western Ontario,1151 Richmond Street, London, ON N6A 5B7 (Canada); Perimeter Institute for Theoretical Physics, 31 Caroline Street North, Waterloo, ON N2L 2Y5 (Canada); Myers, Robert C. [Perimeter Institute for Theoretical Physics, 31 Caroline Street North, Waterloo, ON N2L 2Y5 (Canada)

    2015-02-26

    We expand on the investigation of the universal scaling properties in the early time behaviour of fast but smooth quantum quenches in a general d-dimensional conformal field theory deformed by a relevant operator of dimension Δ with a time-dependent coupling. The quench consists of changing the coupling from an initial constant value λ{sub 1} by an amount of the order of δλ to some other final value λ{sub 2}, over a time scale δt. In the fast quench limit where δt is smaller than all other length scales in the problem, δt≪λ{sub 1}{sup 1/(Δ−d)},λ{sub 2}{sup 1/(Δ−d)},δλ{sup 1/(Δ−d)}, the energy (density) injected into the system scales as δE∼(δλ){sup 2}(δt){sup d−2Δ}. Similarly, the change in the expectation value of the quenched operator at times earlier than the endpoint of the quench scales as 〈O{sub Δ}〉∼δλ (δt){sup d−2Δ}, with further logarithmic enhancements in certain cases. While these results were first found in holographic studies, we recently demonstrated that precisely the same scaling appears in fast mass quenches of free scalar and free fermionic field theories. As we describe in detail, the universal scaling refers to renormalized quantities, in which the UV divergent pieces are consistently renormalized away by subtracting counterterms derived with an adiabatic expansion. We argue that this scaling law is a property of the conformal field theory at the UV fixed point, valid for arbitrary relevant deformations and insensitive to the details of the quench protocol. Our results highlight the difference between smooth fast quenches and instantaneous quenches where the Hamiltonian abruptly changes at some time.

  2. Quality improvement in local health departments: progress, pitfalls, and potential.

    Science.gov (United States)

    Leep, Carolyn; Beitsch, Leslie M; Gorenflo, Grace; Solomon, Jessica; Brooks, Robert G

    2009-01-01

    To assess the current deployment of quality improvement (QI) approaches within local health departments (LHDs) and gain a better understanding of the depth and intensity of QI activities. A mixed quantitative and qualitative approach was employed to determine the current status of QI utilization within LHDs. All respondents from the 2005 NACCHO Profile QI module questionnaire who indicated that their LHD was involved in some kind of QI activity received a follow-up Web-based survey in 2007. A smaller convenience sample of 30 LHDs representing all groups of respondents was selected for the follow-up interview to validate and expound upon survey data. Survey response rate was 62 percent (181/292). Eighty-one percent of LHDs reported QI programmatic activities, with 39 percent occurring agency-wide. Seventy-four percent of health departments had staff trained in QI methods. External funding sources for QI were infrequent (28%). LHDs that were serving large jurisdictions and LHDs that were subunits of state health agencies (centralized states) were more likely to engage in most QI activities. However, interview responses did not consistently corroborate survey results and noted a need for shared definitions. Multiple factors, including funders and accreditation, may be driving the increase of QI for public health. Additional research to confirm and validate these findings is necessary. A common QI vocabulary is also recommended.

  3. Spontaneous quenches of a high temperature superconducting pancake coil

    Energy Technology Data Exchange (ETDEWEB)

    Lue, J.W.; Lubell, M.S. [Oak Ridge National Lab., TN (United States); Aized, D.; Campbell, J.M.; Schwall, R.E. [American Superconductor Corp., Westborough, MA (United States)

    1995-09-01

    A double-pancake coil made of Bi-2223/Ag high temperature superconducting (HTS) tape was constructed with an embedded heater and graded conductors to study the stability and quench propagation in HTS coils. The experiments were performed with liquid nitrogen and gaseous helium cooling in temperatures ranging from 5 to 77 K. The coil was very stable, and no ``normal`` zone was sustained or propagated with local pulsed heating. However, spontaneous quenches of the cod were experienced. This was found to be the result of having the coil current higher than that of the lower I{sub c} sections of the coil for a long time. This quench process took minutes to develop--much longer than would be expected in a low temperature superconducting coil. The quench behaved more like a spreading and continuous heating of an increasingly larger partially resistive section of the coil than like a sequential ``normal`` front propagation.

  4. Localized Density/Drag Prediction for Improved Onboard Orbit Propagation

    Science.gov (United States)

    Stastny, N.; Lin, C.; Lovell, A.; Luck, J.; Chavez, F.

    Since the development of Luigi G. Jacchia's first density model in 1970 (J70), atmospheric density modeling has steadily focused on large monolithic codes that provide global density coverage. The most recent instantiation of the global density model is the Jacchia-Bowman 2008 (JB08) model developed by Bruce Bowman of the Air Force Space Command. As the models have evolved and improved, their complexity has grown as well. Where the J70 model required 2 indices and various time averages to determine density, the JB08 model requires 5 indices to determine density. Due to computational complexity, the number of real-time inputs required, and limited forecasting abilities, these models are not well suited for onboard satellite orbit propagation. In contrast to the global models, this paper proposes the development of a density prediction tool that is only concerned with the trajectory of a specific satellite. Since the orbital parameters of most low Earth orbiting satellites remain relatively constant in the short term, there is also minimal variation in the density profile observed by the satellite. Limiting the density model to a smaller orbit regime will also increase the ability to forecast the density along that orbital track. As a first step, this paper evaluates the feasibility of using a localized density prediction algorithm to generate the density profile that will be seen by satellite, allowing for high-accuracy orbit propagation with minimal or no input from the ground. The algorithm evaluated in this paper is a simple Yule-Walker auto-regressive filter that, given previously measured density values, provides predictions on the upcoming density profile. This first approach requires zero information about the satellite's current orbit, but does require an onboard method for determining the current, local density. Though this aspect of the onboard system is not analyzed here, it is envisioned that this current, local density (or equivalently drag acceleration

  5. Systematic study of particle quenching in organic scintillators

    International Nuclear Information System (INIS)

    Santiago, L.M.; Bagán, H.; Tarancón, A.; Rauret, G.; Garcia, J.F.

    2013-01-01

    Among the different factors that affect measurements by organic scintillators, the majority of attention has been focused on those related to the scintillator (i.e., ionization, chemical, color and optical quenching), and less attention has been paid to the loss of energy before the particle (i.e., alpha or beta) arrives at the scintillator (i.e., particle quenching). This study evaluates the effect of particle quenching in different scintillation methods (i.e., using two plastic scintillation microspheres (PSm1 and PSm2), liquid scintillator and gel scintillator) by measuring solutions that contain increasing concentrations of NaCl, BaCl 2 and glycerin. The results show the importance of particle quenching in PSm measurements because detection efficiency decreases with increasing concentrations of the quenching component, although the spectrum position and external standard parameter remain constant. The results have shown evidence of particle quenching, although at a lower magnitude, in the liquid scintillation or gel scintillation measurements. Moreover, the use of two PSm with different diameters and salty compound that alters the equilibrium of the liquid and gel emulsions also exemplified the importance of the transmission of optical photons through different scintillation media (i.e., optical quenching). Improvement and deterioration of the optical conditions on the scintillation media is manifested as a movement of the spectrum to higher and lower energies, respectively. The results obtained with PSm were confirmed by Monte Carlo simulation.

  6. Systematic study of particle quenching in organic scintillators

    Science.gov (United States)

    Santiago, L. M.; Bagán, H.; Tarancón, A.; Rauret, G.; Garcia, J. F.

    2013-01-01

    Among the different factors that affect measurements by organic scintillators, the majority of attention has been focused on those related to the scintillator (i.e., ionization, chemical, color and optical quenching), and less attention has been paid to the loss of energy before the particle (i.e., alpha or beta) arrives at the scintillator (i.e., particle quenching). This study evaluates the effect of particle quenching in different scintillation methods (i.e., using two plastic scintillation microspheres (PSm1 and PSm2), liquid scintillator and gel scintillator) by measuring solutions that contain increasing concentrations of NaCl, BaCl2 and glycerin. The results show the importance of particle quenching in PSm measurements because detection efficiency decreases with increasing concentrations of the quenching component, although the spectrum position and external standard parameter remain constant. The results have shown evidence of particle quenching, although at a lower magnitude, in the liquid scintillation or gel scintillation measurements. Moreover, the use of two PSm with different diameters and salty compound that alters the equilibrium of the liquid and gel emulsions also exemplified the importance of the transmission of optical photons through different scintillation media (i.e., optical quenching). Improvement and deterioration of the optical conditions on the scintillation media is manifested as a movement of the spectrum to higher and lower energies, respectively. The results obtained with PSm were confirmed by Monte Carlo simulation.

  7. Quench detection in YBa2Cu3O7-δ coated conductors using interferometric techniques

    Science.gov (United States)

    Angurel, L. A.; Martínez, E.; Lera, F.; Recuero, S.; Andrés, N.; Arroyo, M. P.; Xie, Y. Y.; Selvamanickam, V.

    2008-11-01

    Digital speckle pattern interferometry has been used to detect inhomogeneous heating in YBa2Cu3O7-δ coated conductors. The analysis was performed in a sample with a controlled defect, which causes a significant local reduction in the critical current value, Ic. The experiments, which were performed with the sample surrounded by nitrogen vapor, have shown that the location of the initial hot spot leading to the complete transition to the normal state of the conductor (quench) is strongly dependent on the sample cooling configuration. When the sample is mainly cooled by gas convection, the quench always starts in the low-Ic region, while for improved cooling configurations the initial hot spot does not always coincide with this region. The results have been compared with those obtained by direct electric field measurements along the sample in nitrogen vapor and liquid.

  8. An Improved Technique for Robot Global Localization in Indoor Environments

    Directory of Open Access Journals (Sweden)

    Zejian Yuan

    2011-03-01

    Full Text Available Global localization problem is one of the classical and important problems in mobile robot. In this paper, we present an approach to solve robot global localization in indoor environments with grid map. It combines Hough Scan Matching (HSM and grid localization method to get the initial knowledge of robot's pose quickly. For pose tracking, a scan matching technique called Iterative Closest Point (ICP is used to amend the robot motion model, it can drastically decreases the uncertainty about the robot's pose in prediction step. Then accurate proposal distribution taking into account recent observation is introduced into particle filters to recover the best estimate of robot trajectories, which seriously reduces number of particles for pose tracking. The proposed approach can globally localize mobile robot fast and accurately. Experiment results carried out with robot data in indoor environments demonstrates the effectiveness of the proposed approach.

  9. The quench detector on magnetic modulator for the UNK quench protection system

    International Nuclear Information System (INIS)

    Bolotin, I.M.; Enbaev, A.V.; Erokhin, A.N.; Gridasov, V.I.; Priyma, M.V.; Sychev, V.A.; Vasiliev, L.M.

    1992-01-01

    When designing and constructing superconducting high energy accelerators, the development of the Quench Detection System (QDS) for superconducting (SC) magnets becomes an important and critical problem. At present there is experience in developing such systems for the Tevatron (FNAL, USA) and HERA (Hamburg, Germany). The machines for more than 3 TeV-the UNK (Russia) and SSC (USA), which are presently under construction, have very large circumferences, 21 and 87 km, respectively. The QDS's, similar to those of the Tevatron, require a larger part of the active components of the electronic equipment be placed in the machine tunnel close to the magnets, and protected from irradiation or additional surface buildings will have to be constructed. In either case the cost of such a QDS increases. In addition the former ones reliability decreases and maintenance becomes more difficult. For such machines, a QDS in which the quench signal, in each superconducting magnet (SCM) or groups of SCM'S, is extracted with the help of a bridge circuit (BC) appears to be more suitable. The half coils of SCM's are connected as two arms of the bridge and the resistors placed in the vacuum vessels of the magnet cryostats are connected to the other two. The off-balance signal of each BC is enhanced with the help of magnetic amplifiers. This note describes the experimental prototype of a bridge-type Quench Detector (QD) based on a magnetic amplifier Magnetic Modulator (MM) type, allowing one not only to detect a quench in a SCM, but also making feasible a wider system capability, namely: to record the signals from all SC elements during a quench for further analysis of its causes; to check the presence of short circuits of the ring electromagnet bus relative to the cryostats and to localize their position

  10. Thermalization after holographic bilocal quench

    Science.gov (United States)

    Aref'eva, Irina Ya.; Khramtsov, Mikhail A.; Tikhanovskaya, Maria D.

    2017-09-01

    We study thermalization in the holographic (1 + 1)-dimensional CFT after simultaneous generation of two high-energy excitations in the antipodal points on the circle. The holographic picture of such quantum quench is the creation of BTZ black hole from a collision of two massless particles. We perform holographic computation of entanglement entropy and mutual information in the boundary theory and analyze their evolution with time. We show that equilibration of the entanglement in the regions which contained one of the initial excitations is generally similar to that in other holographic quench models, but with some important distinctions. We observe that entanglement propagates along a sharp effective light cone from the points of initial excitations on the boundary. The characteristics of entanglement propagation in the global quench models such as entanglement velocity and the light cone velocity also have a meaning in the bilocal quench scenario. We also observe the loss of memory about the initial state during the equilibration process. We find that the memory loss reflects on the time behavior of the entanglement similarly to the global quench case, and it is related to the universal linear growth of entanglement, which comes from the interior of the forming black hole. We also analyze general two-point correlation functions in the framework of the geodesic approximation, focusing on the study of the late time behavior.

  11. Local randomization in neighbor selection improves PRM roadmap quality

    KAUST Repository

    McMahon, Troy

    2012-10-01

    Probabilistic Roadmap Methods (PRMs) are one of the most used classes of motion planning methods. These sampling-based methods generate robot configurations (nodes) and then connect them to form a graph (roadmap) containing representative feasible pathways. A key step in PRM roadmap construction involves identifying a set of candidate neighbors for each node. Traditionally, these candidates are chosen to be the k-closest nodes based on a given distance metric. In this paper, we propose a new neighbor selection policy called LocalRand(k,K\\'), that first computes the K\\' closest nodes to a specified node and then selects k of those nodes at random. Intuitively, LocalRand attempts to benefit from random sampling while maintaining the higher levels of local planner success inherent to selecting more local neighbors. We provide a methodology for selecting the parameters k and K\\'. We perform an experimental comparison which shows that for both rigid and articulated robots, LocalRand results in roadmaps that are better connected than the traditional k-closest policy or a purely random neighbor selection policy. The cost required to achieve these results is shown to be comparable to k-closest. © 2012 IEEE.

  12. First experience with the new Coupling Loss Induced Quench system

    CERN Document Server

    Ravaioli, E; Dudarev, A V; Kirby, G; Sperin, K A; ten Kate, H H J; Verweij, A P

    2014-01-01

    New-generation high-field superconducting magnets pose a challenge relating to the protection of the coil winding pack in the case of a quench. The high stored energy per unit volume calls for a very efficient quench detection and fast quench propagation in order to avoid damage due to overheating. A new protection system called Coupling-Loss Induced Quench (CLIQ) was recently, developed and tested at CERN. This method provokes a fast change in the magnet transport current by means of a capacitive discharge. The resulting change in the local magnetic field induces inter-filament and inter-strand coupling losses which heat up the superconductor and eventually initiate a quench in a large fraction of the coil winding pack. The method is extensively tested on a Nb-Ti single-wire test solenoid magnet in the CERN Cryogenic Laboratory in order to assess its performance, optimize its operating parameters, and study new electrical configurations. Each parameter is thoroughly analyzed and its impact on the quench effi...

  13. VEHICLE LOCALIZATION BY LIDAR POINT CORRELATION IMPROVED BY CHANGE DETECTION

    Directory of Open Access Journals (Sweden)

    A. Schlichting

    2016-06-01

    Full Text Available LiDAR sensors are proven sensors for accurate vehicle localization. Instead of detecting and matching features in the LiDAR data, we want to use the entire information provided by the scanners. As dynamic objects, like cars, pedestrians or even construction sites could lead to wrong localization results, we use a change detection algorithm to detect these objects in the reference data. If an object occurs in a certain number of measurements at the same position, we mark it and every containing point as static. In the next step, we merge the data of the single measurement epochs to one reference dataset, whereby we only use static points. Further, we also use a classification algorithm to detect trees. For the online localization of the vehicle, we use simulated data of a vertical aligned automotive LiDAR sensor. As we only want to use static objects in this case as well, we use a random forest classifier to detect dynamic scan points online. Since the automotive data is derived from the LiDAR Mobile Mapping System, we are able to use the labelled objects from the reference data generation step to create the training data and further to detect dynamic objects online. The localization then can be done by a point to image correlation method using only static objects. We achieved a localization standard deviation of about 5 cm (position and 0.06° (heading, and were able to successfully localize the vehicle in about 93 % of the cases along a trajectory of 13 km in Hannover, Germany.

  14. Improving aggregate behavior in parking lots with appropriate local maneuvers

    KAUST Repository

    Rodriguez, Samuel

    2013-11-01

    In this paper we study the ingress and egress of pedestrians and vehicles in a parking lot. We show how local maneuvers executed by agents permit them to create trajectories in constrained environments, and to resolve the deadlocks between them in mixed-flow scenarios. We utilize a roadmap-based approach which allows us to map complex environments and generate heuristic local paths that are feasible for both pedestrians and vehicles. Finally, we examine the effect that some agent-behavioral parameters have on parking lot ingress and egress. © 2013 IEEE.

  15. Improving the software fault localization process through testability information

    NARCIS (Netherlands)

    Gonzalez-Sanchez, A.; Abreu, R.; Gross, H.; Van Gemund, A.

    2010-01-01

    When failures occur during software testing, automated software fault localization helps to diagnose their root causes and identify the defective components of a program to support debugging. Diagnosis is carried out by selecting test cases in such way that their pass or fail information will narrow

  16. Effects of quenching and partial quenching on penguin matrix elements

    NARCIS (Netherlands)

    Golterman, Maarten; Pallante, Elisabetta

    2001-01-01

    In the calculation of non-leptonic weak decay rates, a "mismatch" arises when the QCD evolution of the relevant weak hamiltonian down to hadronic scales is performed in unquenched QCD, but the hadronic matrix elements are then computed in (partially) quenched lattice QCD. This mismatch arises

  17. Improving Global Multi-target Tracking with Local Updates

    DEFF Research Database (Denmark)

    Milan, Anton; Gade, Rikke; Dick, Anthony

    2014-01-01

    , which in turn leads to superior per- formance on several challenging benchmark sequences. Additionally, we show tracking results in sports videos where poor video quality and fre- quent and severe occlusions between multiple players pose difficulties for state-of-the-art trackers.......We propose a scheme to explicitly detect and resolve ambiguous situations in multiple target tracking. During periods of uncertainty, our method applies multiple local single target trackers to hypothesise short term tracks. These tracks are combined with the tracks obtained by a global multi......-target tracker, if they result in a reduction in the global cost function. Since tracking failures typically arise when targets become occluded, we propose a local data association scheme to maintain the target identities in these situations. We demonstrate a reduction of up to 50% in the global cost function...

  18. Novel Strategy to Improve the Performance of Localization in WSN

    Directory of Open Access Journals (Sweden)

    M. Vasim Babu

    2015-01-01

    Full Text Available A novel strategy of discrete energy consumption model for WSN based on quasi Monte Carlo and crude Monte Carlo method is developed. In our model the discrete hidden Markov process plays a major role in analyzing the node location in heterogeneous media. In this energy consumption model we use both static and dynamic sensor nodes to monitor the optimized energy of all sensor nodes in which every sensor state can be considered as the dynamic Bayesian network. By using this method the power is assigned in terms of dynamic manner to each sensor over discrete time steps to control the graphical structure of our network. The simulation and experiment result shows that our proposed methods are better in terms of localization accuracy and possess minimum computational time over existing localization method.

  19. Improving High Resolution, Geographically Localized, Short-Term Weather Forcasts

    Science.gov (United States)

    2006-01-03

    M. Corazza , E. Kalnay, D. J. Patil, J. A. Yorke, 2004: A local ensemble Kalman Filter for atmospheric data assimilation. Tellus 56A...415- 428.. 8. Ott, E., B. R. Hunt, I. Szunyogh, A. V. Zimin, E. J. Kostelich, M. Corazza , E. Kalnay, D. J. Patil, and J. A. Yorke, 2004...273- 277. 10. Corazza , M., E. Kalnay, D. J. Patil, R. E. Morss, M. Cai, I. Szunyogh, B. R. Hunt, E. Ott, and J. Yorke, 2003: Use of the

  20. Holographic quenches towards a Lifshitz point

    Energy Technology Data Exchange (ETDEWEB)

    Camilo, Giancarlo [Instituto de Física, Universidade de São Paulo,C.P. 66318, CEP: 05315-970, São Paulo (Brazil); Cuadros-Melgar, Bertha [Escola de Engenharia de Lorena, Universidade de São Paulo,Estrada Municipal do Campinho S/N, CEP: 12602-810, Lorena (Brazil); Abdalla, Elcio [Instituto de Física, Universidade de São Paulo,C.P. 66318, CEP: 05315-970, São Paulo (Brazil)

    2016-02-01

    We use the holographic duality to study quantum quenches of a strongly coupled CFT that drive the theory towards a non-relativistic fixed point with Lifshitz scaling. We consider the case of a Lifshitz dynamical exponent z close to unity, where the non-relativistic field theory can be understood as a specific deformation of the corresponding CFT and, hence, the standard holographic dictionary can be applied. On the gravity side this amounts to finding a dynamical bulk solution which interpolates between AdS and Lishitz spacetimes as time evolves. We show that an asymptotically Lifshitz black hole is always formed in the final state. This indicates that it is impossible to reach the vacuum state of the Lifshitz theory from the CFT vacuum as a result of the proposed quenching mechanism. The nonequilibrium dynamics following the breaking of the relativistic scaling symmetry is also probed using both local and non-local observables. In particular, we conclude that the equilibration process happens in a top-down manner, i.e., the symmetry is broken faster for UV modes.

  1. Heat transfer model for quenching by submerging

    International Nuclear Information System (INIS)

    Passarella, D N; Varas, F; MartIn, E B

    2011-01-01

    In quenching by submerging the workpiece is cooled due to vaporization, convective flow and interaction of both mechanisms. The dynamics of these phenomena is very complex and the corresponding heat fluxes are strongly dependent on local flow variables such as velocity of fluid and vapor fraction. This local dependence may produce very different cooling rates along the piece, responsible for inappropriate metallurgical transformations, variability of material properties and residual stresses. In order to obtain an accurate description of cooling during quenching, a mathematical model of heat transfer is presented here. The model is based on the drift-flux mixture-model for multiphase flows, including an equation of conservation of energy for the liquid phase and specific boundary conditions that account for evaporation and presence of vapor phase on the surface of the piece. The model was implemented on Comsol Multiphysics software. Generation of appropriate initial and boundary conditions, as well as numerical resolution details, is briefly discussed. To test the model, a simple flow condition was analyzed. The effect of vapor fraction on heat transfer is assessed. The presence of the typical vapor blanket and its collapse can be recovered by the model, and its effect on the cooling rates on different parts of the piece is analyzed. Comparisons between numerical results and data from literature are made.

  2. Heat transfer model for quenching by submerging

    Energy Technology Data Exchange (ETDEWEB)

    Passarella, D N; Varas, F [Departamento de Matematica Aplicada II, E.T.S. de Ing. de Telecomunicacion, Universidad de Vigo, Campus Marcosende, 36310 Vigo (Spain); MartIn, E B, E-mail: diego@dma.uvigo.es, E-mail: fvaras@uvigo.es, E-mail: emortega@uvigo.es [Area de Mecanica de Fluidos, E.T.S. de Ing. Industriales, Universidad de Vigo, Campus Marcosende, 36310 Vigo (Spain)

    2011-05-01

    In quenching by submerging the workpiece is cooled due to vaporization, convective flow and interaction of both mechanisms. The dynamics of these phenomena is very complex and the corresponding heat fluxes are strongly dependent on local flow variables such as velocity of fluid and vapor fraction. This local dependence may produce very different cooling rates along the piece, responsible for inappropriate metallurgical transformations, variability of material properties and residual stresses. In order to obtain an accurate description of cooling during quenching, a mathematical model of heat transfer is presented here. The model is based on the drift-flux mixture-model for multiphase flows, including an equation of conservation of energy for the liquid phase and specific boundary conditions that account for evaporation and presence of vapor phase on the surface of the piece. The model was implemented on Comsol Multiphysics software. Generation of appropriate initial and boundary conditions, as well as numerical resolution details, is briefly discussed. To test the model, a simple flow condition was analyzed. The effect of vapor fraction on heat transfer is assessed. The presence of the typical vapor blanket and its collapse can be recovered by the model, and its effect on the cooling rates on different parts of the piece is analyzed. Comparisons between numerical results and data from literature are made.

  3. New Fast Response Thin Film-Based Superconducting Quench Detectors

    CERN Document Server

    Dudarev, A; van de Camp, W; Ravaioli, E; Teixeira, A; ten Kate, H H J

    2014-01-01

    Quench detection on superconducting bus bars and other devices with a low normal zone propagation velocity and low voltage build-up is quite difficult with conventional quench detection techniques. Currently, on ATLAS superconducting bus bar sections, superconducting quench detectors (SQD) are mounted to detect quench events. A first version of the SQD essentially consists of an insulated superconducting wire glued to a superconducting bus line or windings, which in the case of a quench rapidly builds up a relatively high resistance that can be easily and quietly detected. We now introduce a new generation of drastically improved SQDs. The new version makes the detection of quenches simpler, more reliable, and much faster. Instead of a superconducting wire, now a superconducting thin film is used. The layout of the sensor shows a meander like pattern that is etched out of a copper coated 25 mu m thick film of Nb-Ti glued in between layers of Kapton. Since the sensor is now much smaller and thinner, it is easi...

  4. Jet-quenching and correlations

    Indian Academy of Sciences (India)

    2015-05-06

    May 6, 2015 ... Abstract. This article reviews recent advances in our understanding of the experimental aspects of jet-quenching and correlations in relativistic heavy-ion collisions at RHIC and LHC. Emphasis is put on correlation measurements, namely jet-like correlations with anisotropic flow subtraction in heavy-ion ...

  5. Chiral logarithms in quenched QCD

    Energy Technology Data Exchange (ETDEWEB)

    Y. Chen; S. J. Dong; T. Draper; I. Horvath; F. X. Lee; K. F. Liu; N. Mathur; and J. B. Zhang

    2004-08-01

    The quenched chiral logarithms are examined on a 163x28 lattice with Iwasaki gauge action and overlap fermions. The pion decay constant fpi is used to set the lattice spacing, a = 0.200(3) fm. With pion mass as low as {approx}180 MeV, we see the quenched chiral logarithms clearly in mpi2/m and fP, the pseudoscalar decay constant. The authors analyze the data to determine how low the pion mass needs to be in order for the quenched one-loop chiral perturbation theory (chiPT) to apply. With the constrained curve-fitting method, they are able to extract the quenched chiral logarithmic parameter delta together with other low-energy parameters. Only for mpi<=300 MeV do we obtain a consistent and stable fit with a constant delta which they determine to be 0.24(3)(4) (at the chiral scale Lambdachi = 0.8 GeV). By comparing to the 123x28 lattice, they estimate the finite volume effect to be about 2.7% for the smallest pion mass. They also fitted the pion mass to the form for the re-summed cactus diagrams and found that its applicable region is extended farther than the range for the one-loop formula, perhaps up to mpi {approx}500-600 MeV. The scale independent delta is determined to be 0.20(3) in this case. The authors study the quenched non-analytic terms in the nucleon mass and find that the coefficient C1/2 in the nucleon mass is consistent with the prediction of one-loop chiPT. They also obtain the low energy constant L5 from fpi. They conclude from this study that it is imperative to cover only the range of data with the pion mass less than {approx}300 MeV in order to examine the chiral behavior of the hadron masses and decay constants in quenched QCD and match them with quenched one-loop chiPT.

  6. Potential of biofertilisers to improve performance of local genotype tomatoes

    Directory of Open Access Journals (Sweden)

    Carmen Puia

    2017-09-01

    Full Text Available Complex microbial communities in the plant rhizosphere are responsible for their success in ecosystems. Supplementary inoculation of soil with mycorrhizal fungi and rhizospheric bacteria may act as a plant growth-promoting factor. The present study aims to assess the potential use of biofertilisers on tomato as a way of increasing yield and stability of root exploration area. The experiment was set up in greenhouse, regarding the evaluation of growing dynamics of plants, mycorrhization level and obtained yield. The identification of effective inoculation variants can lead to a standardisation of technologies of growing for local plant genotypes. Data analysis was performed based on the ANOVA test, followed by Tukey HSD, principal component analysis and cluster analysis in order to identify the potential of bioproducts to stimulate the development of tomato plants. Application of bacterial biofertilisers does not stimulate enough the aboveground development of plants. An antagonistic reaction is visible between exogenous mycorrhizas and those specific in soil, acting slightly different for each genotype. Mycorrhizal level in root systems is more dependent on applied biofertilisers than on analyzed genotypes. For the variants without additional fertilisers, a high level of mycorrhization is visible only after 75 days from the transplantation. Based on results we can conclude that microbial active fertilisers may represent viable solutions to increase yield capacity and root exploration area for local tomato genotypes.

  7. Improving mobile robot localization: grid-based approach

    Science.gov (United States)

    Yan, Junchi

    2012-02-01

    Autonomous mobile robots have been widely studied not only as advanced facilities for industrial and daily life automation, but also as a testbed in robotics competitions for extending the frontier of current artificial intelligence. In many of such contests, the robot is supposed to navigate on the ground with a grid layout. Based on this observation, we present a localization error correction method by exploring the geometric feature of the tile patterns. On top of the classical inertia-based positioning, our approach employs three fiber-optic sensors that are assembled under the bottom of the robot, presenting an equilateral triangle layout. The sensor apparatus, together with the proposed supporting algorithm, are designed to detect a line's direction (vertical or horizontal) by monitoring the grid crossing events. As a result, the line coordinate information can be fused to rectify the cumulative localization deviation from inertia positioning. The proposed method is analyzed theoretically in terms of its error bound and also has been implemented and tested on a customary developed two-wheel autonomous mobile robot.

  8. Ising antiferromagnet with mobile, pinned, and quenched defects

    Directory of Open Access Journals (Sweden)

    W.Selk

    2005-01-01

    Full Text Available Motivated by recent experiments on (Sr,Ca,La14Cu24O41, a two-dimensional Ising antiferromagnet with mobile, locally pinned and quenched defects is introduced and analyzed using mainly Monte Carlo techniques. The interplay between the arrangement of the defects and the magnetic ordering as well as the effect of an external field are studied.

  9. Extremely high Leidenfrost temperature on nanoparticle-deposited surfaces and its influences on quenching phenomena

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyung Dae [Kyung Hee University, Yongin (Korea, Republic of)

    2010-10-15

    We recently found that quenching behavior of various dilute nanofluids is nearly identical to that of pure water, but due to nanofluids boiling during the quenching process, some nanoparticles deposit on the surface of the rod, which results in much higher quenching rate in subsequent tests with the same object. However the traditional concept of conduction controlled quenching cannot explain the acceleration provided by the nanoparticle layer on the surface. In this study, we study effects of nanoparticle deposition on evaporation and rewetting of a single sessile droplet of water. Leidenfrost temperature closely associated with the quenching phenomena is investigated on clean and nanoparticle-deposited surfaces by measuring total evaporation time of a droplet. The possible mechanisms responsible for the quench acceleration on the nanoparticle-deposited surfaces will be discussed with the relation between the localized rewetting of the heated surface even above the Leidenfrost temperature and the destabilization of the film-boiling vapor film

  10. Ebola Crisis: Improving Science-Based Communication and Local ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    As a long-term goal, the project aims to strengthen journalism associations in Africa through country and regional exchanges using a Web-based platform devoted to science and health journalism. This will help increase access to health knowledge and evidence, improve monitoring and reporting of priority health issues in ...

  11. Improved ATLAS HammerCloud Monitoring for local Site Administration

    CERN Document Server

    Boehler, Michael; The ATLAS collaboration; Hoenig, Friedrich; Legger, Federica; Sciacca, Francesco Giovanni; Mancinelli, Valentina

    2015-01-01

    Every day hundreds of tests are run on the Worldwide LHC Computing Grid for the ATLAS, and CMS experiments in order to evaluate the performance and reliability of the different computing sites. All this activity is steered, controlled, and monitored by the HammerCloud testing infrastructure. Sites with failing functionality tests are auto-excluded from the ATLAS computing grid, therefore it is essential to provide a detailed and well organized web interface for the local site administrators such that they can easily spot and promptly solve site issues. Additional functionality has been developed to extract and visualize the most relevant information. The site administrators can now be pointed easily to major site issues which lead to site blacklisting as well as possible minor issues that are usually not conspicuous enough to warrant the blacklisting of a specific site, but can still cause undesired effects such as a non-negligible job failure rate. This paper summarizes the different developments and optimiz...

  12. Fuel rod quenching with oxidation and precursory cooling

    International Nuclear Information System (INIS)

    Davidi, A.; Elias, E.; Olek, S.

    1999-01-01

    During a loss-of-coolant-accident in LWR fuel rods may be temporarily exposed thus reaching high temperature levels. The injection of cold water into the core, while providing the necessary cooling to prevent melting may also generate steam inducing exothermal oxidation of the cladding. A number of high temperature quenching experiments [I] have demonstrated that during the early phase of the quenching process, the rate of hydrogen generation increased markedly and the surface temperatures rose rapidly. These effects are believed to result from thermal stresses breaking up the oxide layer on the zircalloy cladding, thus exposing the inner surface to oxidizing atmosphere. Steam reacts exothermally with the metallic components of the newly formed surface causing temporarily local temperature escalation. The main objective of this study is to develop and assess a one-dimensional time-dependent rewetting model to address the problem of quenching of hot surfaces undergoing exothermic oxidation reactions. Addressing a time-dependent problem is an important aspect of the work since it is believed that the progression of a quench-front along a hot oxidizing surface is an unsteady process. Several studies dealing with time-dependent rewetting problems have been published, e.g. [2]-[5], but none considers oxidation reactions downstream of the quench-front. The main difficulty in solving time-dependent rewetting problems stems from the fact that either the quench-front velocity or the quench-front positions constitute a time-dependent eigenvalue of the problem. The model is applied to describe the interrelated processes of cooling and exothermic steam-metal reactions at the vapor zirconium-cladding interface during quenching of degraded fuel rods. A constant heat transfer coefficient is assumed upstream of the quenching front whereas the combined effect of oxidation and post dry-out cooling is described by prescribing a heat flux distribution of general form downstream. The

  13. Screening and Improvement of Local Isolates of Aspergillus Niger ...

    African Journals Online (AJOL)

    The isolate CP3 was chosen for further studies. Strain improvement studies which was based on exposure of CP3 to ultraviolet irradiation for 10, 30 and 45 minutes increased citric acid yield to 22.20g/l (48.89% increase) by mutant M45 followed by a citric acid yield of 16.22g/l by the 30 minutes mutant (M30) and the least ...

  14. Quench Simulation Studies: Program documentation of SPQR

    CERN Document Server

    Sonnemann, F

    2001-01-01

    Quench experiments are being performed on prototypes of the superconducting magnets and busbars to determine the adequate design and protection. Many tests can only be understood correctly with the help of quench simulations that model the thermo-hydraulic and electrodynamic processes during a quench. In some cases simulations are the only method to scale the experimental results of prototype measurements to match the situation of quenching superconducting elements in the LHC. This note introduces the theoretical quench model and the use of the simulation program SPQR (Simulation Program for Quench Research), which has been developed to compute the quench process in superconducting magnets and busbars. The model approximates the heat balance equation with the finite difference method including the temperature dependence of the material parameters. SPQR allows the simulation of longitudinal quench propagation along a superconducting cable, the transverse propagation between adjacent conductors, heat transfer i...

  15. Livestock Development Based on Local Resources to Decreasing of Dependency Level and Improve of Community Economics

    OpenAIRE

    Hartoko, Hartoko

    2001-01-01

    To decrease the level of dependency on import goods, it is necessary to develop local based animal husbandry. This action has an important meaning in order to improve community economics in Indonesia.  Some ideas to motivate the development of the local based animal husbandry, are: first, mapping of the local resources, including specific superior local animals. Second, to support the continuity of feedstuffs production. Third, germ plasm / genuine animal conservation. Fourth, publication  of...

  16. Local food policies can help promote local foods and improve health: a case study from the Federated States of Micronesia.

    Science.gov (United States)

    Englberger, Lois; Lorens, Adelino; Pretrick, Moses; Tara, Mona J; Johnson, Emihner

    2011-11-01

    The Federated States of Micronesia (FSM) and other countries throughout the Pacific are facing an epidemic of non-communicable disease health problems. These are directly related to the increased consumption of unhealthy imported processed foods, the neglect of traditional food systems, and lifestyle changes, including decreased physical activity. The FSM faces the double burden of malnutrition with both non-communicable diseases and micronutrient deficiencies, including vitamin A deficiency and anemia. To help increase the use of traditional island foods and improve health, the Island Food Community of Pohnpei has initiated a program in the FSM to support and promote local food policies, along with its Go Local awareness campaign. Such local food policies are defined broadly and include individual and family commitments, community group local food policies and policies established by government, including presidential proclamations and increased taxation on soft drinks. The aim of this paper is to describe this work. An inter-agency, community- and research-based, participatory and media approach was used. Partners are both non-governmental and governmental. The use of continuing awareness work along with local food policy establishment and the acknowledgement of the individuals and groups involved are essential. The work is still in the preliminary stage but ad hoc examples show that this approach has had success in increased awareness on health issues and improving dietary intake on both an individual and group basis. This indicates that further use of local food policies could have an instrumental impact in FSM as well as other Pacific Island countries in promoting local foods and improving dietary intake and health, including the control of non-communicable diseases and other dietary-related health problems.

  17. [Recommendations for making quality improvements in administration within local authorities].

    Science.gov (United States)

    Sekiyama, Masahito

    2002-05-01

    To ascertain the methods and issues of industrial administration, that have been systematically chosen by the health and welfare administration in the Iwate Prefectural Government, in order to increase public customer satisfaction. Combined use of TQM and marketing is thought to be the most effective way to increase public customer satisfaction with limited resources. This method secures a quality administrative service capable of corresponding to public needs, by improvement of processes and resources. Therefore we made use of both TQM and marketing. According to a customer satisfaction survey conducted by Iwate Prefectural Government in May 2001 (mail survey, sent to 234 people, response rate of 88.9%), public customer satisfaction had increased compared to the previous year in the following areas: provision for the elderly, the declining birthrate, disabled persons and universal design. Also, in a policy evaluation conducted during the same year, 207 services were revised and 30 were temporarily closed, abolished or reduced, 20 were merged, and 23 were expanded. We cannot sufficiently evaluate the effectiveness of the methods yet because they were only just introduced. However, development of the plan and policy evaluation appear to have been quite effective. From now on we will continue to improve our methods, especially to increase the quality of our administrative resources.

  18. Numerical analysis of quench in coated conductors with defects

    Directory of Open Access Journals (Sweden)

    Wenbin Liu

    2016-09-01

    Full Text Available When the superconductor is subjected to local thermal perturbations, a large amount of joule heat may be generated in the conductor, which may lead to a quench. In a quench event, a normal zone irreversibly spreads throughout the conductor leading to failure of the superconducting device. In this paper, we will discuss the one-dimensional quench behavior in the coated conductors with internal defects or interface defects. Based on the numerical procedure given in the previous works, the normal zone propagation is studied by using the finite difference method. The numerical results are presented to discuss the normal zone propagation. We consider the effect of internal defect on the nonuniform temperature propagation. For the conductor with interface defects, it can be found that the normal zone propagation velocity is increased by defects.

  19. Study of piezo-actuators for the improvement of the frequency tuning and setup of a quench locating system for the accelerating structures of the S-DALINAC; Untersuchung von Piezoaktuatoren zur Verbesserung der Frequenzabstimmung und Aufbau eines Quenchortungssystems fuer die Beschleunigungsstrukturen des S-DALINAC

    Energy Technology Data Exchange (ETDEWEB)

    Sievers, Sven Thorsten

    2013-07-08

    The intention of this doctoral thesis was to find a replacement for the magnetostrictive fine tuners of the superconducting accelerating cavities of the S-DALINAC and to enlarge the range of diagnostics for these cavities. For these purposes a vertical bath cryostat has been assembled and put into operation. Within the framework of this thesis that cryostat was used (i) to test stroke and reliability of modern piezo actuators in liquid helium at 4 and 2 K and (ii) to set up a newly developed system for the localization of quenches in superconducting cavities based on second sound in superfluid helium. The negative impact of magnetic fields on the quality factor of superconducting cavities make the operation of magnetostrictive tuners nearby the cavities disadvantageous. In order to avoid a decrease of the quality factor of the cavities the magnetostrictive tuners should be replaced by non-magnetic ones. For that purpose modern piezo actuators were tested within this doctoral thesis relating to their stroke at cryogenic temperatures, their compatibility with the RF-control system of the S-DALINAC and their operational reliability in superfluid helium. The results indicate the possibility of operation of these actuators. Because piezo actuators of the same stroke only have the seventh part of length of a magnetostrictive tuner, it is possible to operate several piezo actuators at every cavity. This increases not only the range of the tuning system but also its reliability. Already tiny defects at the inner surface of superconducting cavities can cause quenching before the designed field intensity is reached. A quench results in waves of second sound in superfluid helium. The second sound can be measured by special microphones, so called Oscillating Superleak Transducers (OST), and the location of quenching can be calculated via triangulation. Such a system has been built up and tested successfully in the context of this doctoral thesis. The visual examination of the

  20. Quenched Reinforcement Exposed to Fire

    DEFF Research Database (Denmark)

    Hertz, Kristian Dahl

    2006-01-01

    Idealized data are derived for the tensile strength of quenched and tempered prestressing steel and of quenched and self-tempered reinforcing bars for fire safety design. 0.2% stresses are derived as a function of the maximum temperature and in addition, 2.0% stresses are provided. A strain of 2.......0% is seldom found in “slack” (not prestressed) reinforcement, but 2.0% stresses might be relevant for reinforcement in T shaped cross sections and for prestressed structures, where large strains can be applied. All data are provided in a “HOT” condition during a fire and in a “COLD” condition after a fire....... The COLD condition is relevant for analyses of residual load bearing capacity of a structure after a fire exposure. It is also relevant for analyses of concrete structures exposed to fully developed fire courses. The reason is that compression zones of concrete are always the weakest in the cooling phase...

  1. Idebenone: Novel Strategies to Improve Its Systemic and Local Efficacy

    Directory of Open Access Journals (Sweden)

    Lucia Montenegro

    2018-02-01

    Full Text Available The key role of antioxidants in treating and preventing many systemic and topical diseases is well recognized. One of the most potent antioxidants available for pharmaceutical and cosmetic use is Idebenone (IDE, a synthetic analogue of Coenzyme Q10. Unfortunately, IDE’s unfavorable physicochemical properties such as poor water solubility and high lipophilicity impair its bioavailability after oral and topical administration and prevent its parenteral use. In recent decades, many strategies have been proposed to improve IDE effectiveness in the treatment of neurodegenerative diseases and skin disorders. After a brief description of IDE potential therapeutic applications and its pharmacokinetic and pharmacodynamic profile, this review will focus on the different approaches investigated to overcome IDE drawbacks, such as IDE incorporation into different types of delivery systems (liposomes, cyclodextrins, microemulsions, self-micro-emulsifying drug delivery systems, lipid-based nanoparticles, polymeric nanoparticles and IDE chemical modification. The results of these studies will be illustrated with emphasis on the most innovative strategies and their future perspectives.

  2. The LHC quench protection system

    CERN Multimedia

    2009-01-01

    The new quench protection system (QPS) has the crucial roles of providing an early warning for any part of the superconducting coils and busbars that develop high resistance, as well as triggering the switch-off of the machine. Over 2000 new detectors will be installed around the LHC to make sure every busbar segment between magnets is monitored and protected. One of the major consolidation activities for the LHC is the addition of two new detectors to the quench protection system. A magnet quench occurs when part of the superconducting cable becomes normally-conducting. When the protection system detects an increased resistance the huge amount of energy stored in the magnet chains is safely extracted and ‘dumped’ into specially designed resistors. In the case of the main dipole chain, the stored energy in a single LHC sector is roughly the same as the kinetic energy of a passenger jet at cruising speed. The first new detector is designed to monitor the superconducting...

  3. PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes.

    Science.gov (United States)

    Yu, Nancy Y; Wagner, James R; Laird, Matthew R; Melli, Gabor; Rey, Sébastien; Lo, Raymond; Dao, Phuong; Sahinalp, S Cenk; Ester, Martin; Foster, Leonard J; Brinkman, Fiona S L

    2010-07-01

    PSORTb has remained the most precise bacterial protein subcellular localization (SCL) predictor since it was first made available in 2003. However, the recall needs to be improved and no accurate SCL predictors yet make predictions for archaea, nor differentiate important localization subcategories, such as proteins targeted to a host cell or bacterial hyperstructures/organelles. Such improvements should preferably be encompassed in a freely available web-based predictor that can also be used as a standalone program. We developed PSORTb version 3.0 with improved recall, higher proteome-scale prediction coverage, and new refined localization subcategories. It is the first SCL predictor specifically geared for all prokaryotes, including archaea and bacteria with atypical membrane/cell wall topologies. It features an improved standalone program, with a new batch results delivery system complementing its web interface. We evaluated the most accurate SCL predictors using 5-fold cross validation plus we performed an independent proteomics analysis, showing that PSORTb 3.0 is the most accurate but can benefit from being complemented by Proteome Analyst predictions. http://www.psort.org/psortb (download open source software or use the web interface). psort-mail@sfu.ca Supplementary data are available at Bioinformatics online.

  4. Facial expression recognition based on improved local ternary pattern and stacked auto-encoder

    Science.gov (United States)

    Wu, Yao; Qiu, Weigen

    2017-08-01

    In order to enhance the robustness of facial expression recognition, we propose a method of facial expression recognition based on improved Local Ternary Pattern (LTP) combined with Stacked Auto-Encoder (SAE). This method uses the improved LTP extraction feature, and then uses the improved depth belief network as the detector and classifier to extract the LTP feature. The combination of LTP and improved deep belief network is realized in facial expression recognition. The recognition rate on CK+ databases has improved significantly.

  5. Interactions between natural organic ligands and trace metals studied by fluorescence lifetime and fluorescence quenching

    Science.gov (United States)

    Nouhi, Ayoub; Hajjoul, Houssam; Redon, Roland; Gagné, Jean-Pierre; Mounier, Stéphane

    2017-04-01

    Improved insight on the interactions between natural organic ligands and trace metals is of paramount importance for better understanding transport and toxicity pathways of metal ions in the environment. Fluorescence spectroscopy allows introspecting ligands-metals interactions. Time-resolved laser fluorescence spectroscopy (TRLFS) measures fluorophore lifetime probing the local molecular environment. Excitation Emission Fluorescence Matrices (EEFMs) and their statistical treatment : parallel factor analysis (PARAFAC) using PROGMEEF Matlab homemade program, can give insight on the number or nature of organic fluorophores involved in the interactions. Quenching of fluorescence by metals can occur following two processes: dynamic and static quenching (Lakowicz, 2013). In the first case, quenching is caused by physical collisions among molecules and in the second case fluorophores can form nonfluorescent complexes with quenchers. It is possible to identify the different mechanisms because each type of quenching corresponds to a different mathematical model (Lakowicz, 2013; Valeur and Berberan-Santos, 2012). In TRLFS, the study of fluorescence decay's laws induced by nanosecond pulsed laser will allow to exactly qualify the type of interaction. The crucial point of the temporal deconvolution will be the evaluation of the best fitting between the different physical models and the decays measured. From the most suitable time decay model, it will be possible to deduce the quenching which modifies the fluorescence. The aim of this study was to characterize interactions between natural organic ligands and trace metals using fluorescence tools to evaluate the fluorescence lifetime of the fluorophore, the occurrence of quenching in presence of metal, discuss its mechanism and estimate conditional stability constants if a complex organic ligand-metal is formed. This study has been done in two steps. First, we have examined the interactions between salicylic acid and copper in

  6. Improvement of Accuracy in Damage Localization Using Frequency Slice Wavelet Transform

    Directory of Open Access Journals (Sweden)

    Xinglong Liu

    2012-01-01

    Full Text Available Damage localization is a primary objective of damage identification. This paper presents damage localization in beam structure using impact-induced Lamb wave and Frequency Slice Wavelet Transform (FSWT. FSWT is a new time-frequency analysis method and has the adaptive resolution feature. The time-frequency resolution is a vital factor affecting the accuracy of damage localization. In FSWT there is a unique parameter controlling the time-frequency resolution. To improve the accuracy of damage localization, a generalized criterion is proposed to determine the parameter value for achieving a suitable time-frequency resolution. For damage localization, the group velocity dispersion curve (GVDC of A0 Lamb waves in beam is first accurately estimated using FSWT, and then the arrival times of reflection wave from the crack for some individual frequency components are determined. An average operation on the calculated propagation distance is then performed to further improve the accuracy of damage localization.

  7. 2D/3D quench simulation using ANSYS for epoxy impregnated Nb3Sn high field magnets

    Energy Technology Data Exchange (ETDEWEB)

    Ryuji Yamada et al.

    2002-09-19

    A quench program using ANSYS is developed for the high field collider magnet for three-dimensional analysis. Its computational procedure is explained. The quench program is applied to a one meter Nb{sub 3}Sn high field model magnet, which is epoxy impregnated. The quench simulation program is used to estimate the temperature and mechanical stress inside the coil as well as over the whole magnet. It is concluded that for the one meter magnet with the presented cross section and configuration, the thermal effects due to the quench is tolerable. But we need much more quench study and improvements in the design for longer magnets.

  8. Analysis of Intracellular Metabolites from Microorganisms: Quenching and Extraction Protocols.

    Science.gov (United States)

    Pinu, Farhana R; Villas-Boas, Silas G; Aggio, Raphael

    2017-10-23

    Sample preparation is one of the most important steps in metabolome analysis. The challenges of determining microbial metabolome have been well discussed within the research community and many improvements have already been achieved in last decade. The analysis of intracellular metabolites is particularly challenging. Environmental perturbations may considerably affect microbial metabolism, which results in intracellular metabolites being rapidly degraded or metabolized by enzymatic reactions. Therefore, quenching or the complete stop of cell metabolism is a pre-requisite for accurate intracellular metabolite analysis. After quenching, metabolites need to be extracted from the intracellular compartment. The choice of the most suitable metabolite extraction method/s is another crucial step. The literature indicates that specific classes of metabolites are better extracted by different extraction protocols. In this review, we discuss the technical aspects and advancements of quenching and extraction of intracellular metabolite analysis from microbial cells.

  9. Simulations of quench and recovery in CICC conductors

    International Nuclear Information System (INIS)

    Schultz, J.H.; Hale, J.R.; Minervini, J.; Steeves, M.

    1992-01-01

    In the past few years, several computer codes have been written for the purpose of analyzing transient recovery and quench in internally-cooled cable-in-conduit superconductors (ICCS). These codes all include a transient, compressible helium flow model. They differ in the dimensionality of the models, ranging from one to three dimensional finite element modelling of thermal conduction. The code used in this study, Wong's CICC, is a 1 1/2 D code that models thermal conduction through the insulation of an individual conduit. Until recently, the calibration of CICC was restricted to measurements of helium expulsion in normal conductor. No actual quenches in ICCS coils had been simulated. In the past year, several experiments on ICCS conductors of differing topology have been performed and compared with CICC simulations, with varying success. This paper reports on the capability of CICC to predict and analyze ICCS recovery and quench, and on the code's limitations and need for further improvements

  10. Improving Elementary School Students’ English Vocabulary Through Local Cultural Content Materials

    OpenAIRE

    Frans Manurung; Ignatius Harjanto

    2015-01-01

    Abstract Elementary students of a certain public school in Indonesia had difficulties in learning English. One of the crucial problems was learning English vocabulary. In an attempt to help the students learn and improve English vocabulary, the researchers decided to use CAR to teach English vocabulary with local cultural content materials. The aim of this study was to investigate how the teaching of English vocabulary with local cultural content materials contributed to the improvement ...

  11. Jet Quenching via Jet Collimation

    CERN Document Server

    Casalderrey-Solana, Jorge; Wiedemann, Urs Achim

    2011-01-01

    The ATLAS Collaboration recently reported strong modifications of dijet properties in heavy ion collisions. In this work, we discuss to what extent these first data constrain already the microscopic mechanism underlying jet quenching. Simple kinematic arguments lead us to identify a frequency collimation mechanism via which the medium efficiently trims away the soft components of the jet parton shower. Through this mechanism, the observed dijet asymmetry can be accomodated with values of $\\hat{q}\\, L$ that lie in the expected order of magnitude.

  12. Adjuvant Radiation Therapy Improves Local Control After Surgical Resection in Patients With Localized Adrenocortical Carcinoma

    International Nuclear Information System (INIS)

    Sabolch, Aaron; Else, Tobias; Griffith, Kent A.; Ben-Josef, Edgar; Williams, Andrew; Miller, Barbra S.; Worden, Francis; Hammer, Gary D.; Jolly, Shruti

    2015-01-01

    Purpose: Adrenocortical carcinoma (ACC) is a rare malignancy known for high rates of local recurrence, though the benefit of postoperative radiation therapy (RT) has not been established. In this study of grossly resected ACC, we compare local control of patients treated with surgery followed by adjuvant RT to a matched cohort treated with surgery alone. Methods and Materials: We retrospectively identified patients with localized disease who underwent R0 or R1 resection followed by adjuvant RT. Only patients treated with RT at our institution were included. Matching to surgical controls was on the basis of stage, surgical margin status, tumor grade, and adjuvant mitotane. Results: From 1991 to 2011, 360 ACC patients were evaluated for ACC at the University of Michigan (Ann Arbor, MI). Twenty patients with localized disease received postoperative adjuvant RT. These were matched to 20 controls. There were no statistically significant differences between the groups with regard to stage, margins, grade, or mitotane. Median RT dose was 55 Gy (range, 45-60 Gy). Median follow-up was 34 months. Local recurrence occurred in 1 patient treated with RT, compared with 12 patients not treated with RT (P=.0005; hazard ratio [HR] 12.59; 95% confidence interval [CI] 1.62-97.88). However, recurrence-free survival was no different between the groups (P=.17; HR 1.52; 95% CI 0.67-3.45). Overall survival was also not significantly different (P=.13; HR 1.97; 95% CI 0.57-6.77), with 4 deaths in the RT group compared with 9 in the control group. Conclusions: Postoperative RT significantly improved local control compared with the use of surgery alone in this case-matched cohort analysis of grossly resected ACC patients. Although this retrospective series represents the largest study to date on adjuvant RT for ACC, its findings need to be prospectively confirmed

  13. Non-kinematic Flux-transport Dynamos Including the Effects of Diffusivity Quenching

    Energy Technology Data Exchange (ETDEWEB)

    Ichimura, Chiaki; Yokoyama, Takaaki [Department of Earth and Planetary Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2017-04-10

    Turbulent magnetic diffusivity is quenched when strong magnetic fields suppress turbulent motion in a phenomenon known as diffusivity quenching. Diffusivity quenching can provide a mechanism for amplifying magnetic field and influencing global velocity fields through Lorentz force feedback. To investigate this effect, we conducted mean field flux-transport dynamo simulations that included the effects of diffusivity quenching in a non-kinematic regime. We found that toroidal magnetic field strength is amplified by up to approximately 1.5 times in the convection zone as a result of diffusivity quenching. This amplification is much weaker than that in kinematic cases as a result of Lorentz force feedback on the system’s differential rotation. While amplified toroidal fields lead to the suppression of equatorward meridional flow locally near the base of the convection zone, large-scale equatorward transport of magnetic flux via meridional flow, which is the essential process of the flux-transport dynamo, is sustainable in our calculations.

  14. Improved localization accuracy in stochastic super-resolution fluorescence microscopy by K-factor image deshadowing.

    Science.gov (United States)

    Ilovitsh, Tali; Meiri, Amihai; Ebeling, Carl G; Menon, Rajesh; Gerton, Jordan M; Jorgensen, Erik M; Zalevsky, Zeev

    2013-12-16

    Localization of a single fluorescent particle with sub-diffraction-limit accuracy is a key merit in localization microscopy. Existing methods such as photoactivated localization microscopy (PALM) and stochastic optical reconstruction microscopy (STORM) achieve localization accuracies of single emitters that can reach an order of magnitude lower than the conventional resolving capabilities of optical microscopy. However, these techniques require a sparse distribution of simultaneously activated fluorophores in the field of view, resulting in larger time needed for the construction of the full image. In this paper we present the use of a nonlinear image decomposition algorithm termed K-factor, which reduces an image into a nonlinear set of contrast-ordered decompositions whose joint product reassembles the original image. The K-factor technique, when implemented on raw data prior to localization, can improve the localization accuracy of standard existing methods, and also enable the localization of overlapping particles, allowing the use of increased fluorophore activation density, and thereby increased data collection speed. Numerical simulations of fluorescence data with random probe positions, and especially at high densities of activated fluorophores, demonstrate an improvement of up to 85% in the localization precision compared to single fitting techniques. Implementing the proposed concept on experimental data of cellular structures yielded a 37% improvement in resolution for the same super-resolution image acquisition time, and a decrease of 42% in the collection time of super-resolution data with the same resolution.

  15. Rapid Quench in an Electrostatic Levitator

    Science.gov (United States)

    SanSoucie, Michael P.; Rogers, Jan R.; Matson, Douglas M.

    2016-01-01

    The Electrostatic Levitation (ESL) Laboratory at the NASA Marshall Space Flight Center (MSFC) is a unique facility for investigators studying high-temperature materials. The ESL laboratory's main chamber has been upgraded with the addition of a rapid quench system. This system allows samples to be dropped into a quench vessel that can be filled with a low melting point material, such as a gallium or indium alloy, as a quench medium. Thereby allowing rapid quenching of undercooled liquid metals. Up to eight quench vessels can be loaded into a wheel inside the chamber that is indexed with control software. The system has been tested successfully with samples of zirconium, iron-cobalt alloys, titanium-zirconium-nickel alloys, and a silicon-cobalt alloy. This new rapid quench system will allow materials science studies of undercooled materials and new materials development. In this presentation, the system is described and some initial results are presented.

  16. Quenching behaviour of hot zircaloy tube

    International Nuclear Information System (INIS)

    Chinchole, A.S.; Kulkarni, P.P.; Nayak, A.K.; Vijayan, P.K.

    2015-01-01

    The quenching process plays a very important role in case of safety of nuclear reactors. During large break Loss of Coolant Accident in a nuclear reactor, the cooling water from the system is lost. Under this condition, cold water is injected from emergency core cooling system. Quenching behaviour of such heated rod bundle is really complex. It is well known that nanofluids have better heat removal capability and high heat transfer coefficient owing to enhanced thermal properties. Alumina nano-particles result in better cooling abilities compared with the traditionally used quenching media. In this paper, the authors have carried out experiments on quenching behaviour of hot zircaloy tube with demineralized water and nanofluids. It was observed that, the tube got quenched within few seconds even with the presence of decay heat and shows slightly reduced quenching time compared with DM water. (author)

  17. Quench determination in liquid scintillation counting systems

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    A method and apparatus for measuring the degree of quench in a liquid scintillation sample by irradiating the sample with a standard source, such as a cesium-137 gamma source, to produce a Compton scattered electron distribution exhibiting a Compton edge configuration as the leading edge are described. For increasing the quench levels in the sample, the Compton edge shifts to lower pulse height values and the extent of this shift is indicative of the degree of quench. To measure the degree of quench, a unique point on the Compton edge, namely the point at which the second derivative of the edge is zero (i.e. the inflection point), is measured for the quenched sample and the pulse height value corresponding to the inflection point is determined. The pulse height value is compared with the pulse height value determined for a calibration standard in a similar manner, the difference in pulse height values indicating the degree of quench

  18. Influence of the laser pre-quenched substrate on an electroplated chromium coating/steel substrate

    Science.gov (United States)

    Chen, Xuejun; Yan, Qian; Ma, Qian

    2017-05-01

    The chromium coatings were electroplated onto a laser pre-quenched steel substrate to improve the interfacial adhesion properties of chromium coating/steel substrate system. The influence of laser pre-treatment on the substrate, coating as well as interface was investigated by using microstructure characterization, hardness testing, tensile testing and finite element analysis. An apparent boundary line instead of an interlayer was identified between chromium coating/pre-quenched steel substrate. The Vickers hardness and yield strength of steel substrate were significantly improved after laser pre-quenching. The fracture toughness of chromium coating was increased by about 28.6% compared to the un-treated counterpart. The energy release rate for an interfacial crack in the chromium coating/laser-quenched substrate was smaller than that in the untreated specimen. These results may help understand the life prolongation mechanism for the laser pre-quenched chromium/coated steel parts.

  19. Improved quality of beneath-canopy grass in South African savannas: Local and seasonal variation

    NARCIS (Netherlands)

    Treydte, A.C.; Looringh van Beeck, F.A.; Ludwig, F.; Heitkonig, I.M.A.

    2008-01-01

    Questions: Do large trees improve the nutrient content and the structure of the grass layer in savannas? Does the magnitude of this improvement differ with locality ( soil nutrients) and season ( water availability)? Are grass structure and species composition beneath tree canopies influenced by

  20. Improving rehabilitation treatment in a local setting : a case study of prosthetic rehabilitation

    NARCIS (Netherlands)

    van Twillert, Sacha; Postema, Klaas; Geertzen, Jan H. B.; Hemminga, Titia; Lettinga, Ant T.

    2009-01-01

    Objective: To contribute to the discussion on the research-practice gap by illustrating obstacles and opportunities that arise in an evidence-informed improvement process of prosthetic rehabilitation in a local setting. Setting: Dutch rehabilitation centre. Presupposition: The improvement process

  1. Improving the early presentation of cancer symptoms in disadvantaged communities: putting local people in control

    OpenAIRE

    Lyon, D; Knowles, J; Slater, B; Kennedy, R

    2009-01-01

    Background and aims: Premature deaths from cancer affect deprived communities disproportionately. The Department of Health has funded a programme in 19 Spearhead PCTs, delivered by the Improvement Foundation, to promote the early presentation and diagnosis of breast, bowel and lung cancers, with the ultimate intention of improving outcomes. Methods: The programme uses improvement methodology and is a unique approach involving local people working in partnership in their communities to raise a...

  2. Quenched and Partially Quenched Chiral Perturbation Theory for Vector and Tensor Mesons

    OpenAIRE

    Chow, Chi-Keung; Rey, Soo-Jong

    1997-01-01

    Quenched and partially quenched chiral perturbation theory for vector mesons is developed and is used to extract chiral loop correction to the $\\rho$ meson mass. Connections to fully quenched and totally unquenched chiral perturbation theory results are discussed. It is also shown that (partially) quenched perturbation theory for tensor mesons can be formulated analogously, and the chiral corrections for tensor meson masses are directly proportional to their counterparts in the vector meson s...

  3. Improved Beam Angle Arrangement in Intensity Modulated Proton Therapy Treatment Planning for Localized Prostate Cancer

    International Nuclear Information System (INIS)

    Cao, Wenhua; Lim, Gino J.; Li, Yupeng; Zhu, X. Ronald; Zhang, Xiaodong

    2015-01-01

    Purpose: This study investigates potential gains of an improved beam angle arrangement compared to a conventional fixed gantry setup in intensity modulated proton therapy (IMPT) treatment for localized prostate cancer patients based on a proof of principle study. Materials and Methods: Three patients with localized prostate cancer retrospectively selected from our institution were studied. For each patient, IMPT plans were designed using two, three and four beam angles, respectively, obtained from a beam angle optimization algorithm. Those plans were then compared with ones using two lateral parallel-opposed beams according to the conventional planning protocol for localized prostate cancer adopted at our institution. Results: IMPT plans with two optimized angles achieved significant improvements in rectum sparing and moderate improvements in bladder sparing against those with two lateral angles. Plans with three optimized angles further improved rectum sparing significantly over those two-angle plans, whereas four-angle plans found no advantage over three-angle plans. A possible three-beam class solution for localized prostate patients was suggested and demonstrated with preserved dosimetric benefits because individually optimized three-angle solutions were found sharing a very similar pattern. Conclusions: This study has demonstrated the potential of using an improved beam angle arrangement to better exploit the theoretical dosimetric benefits of proton therapy and provided insights of selecting quality beam angles for localized prostate cancer treatment

  4. Spectral analysis of colour-quenched and chemically quenched C 14 samples

    International Nuclear Information System (INIS)

    Grau Malonda, A.; Scott Guillearrd, P.E.

    1987-01-01

    Pairs of pulse height distribution curves, of C-14 samples, colour quenched and chemically quenched were obtained. The possibility to choose a counting window in order to obtain the counting efficiency curves, for both type of quenching was studied. (author). 7 figs., 7 refs

  5. Spectral analysis of colour-quenched and chemically quenched C-14 samples

    International Nuclear Information System (INIS)

    Scott, P. E.; Grau, A.

    1987-01-01

    In this paper pairs of pulse height distribution curves, of C-14 samples, colour-quenched and chemically quenched was obtained. The possibility to choose a counting window in order to obtain the counting efficiency curves, for both type of quenching was studied. (Author) 7 refs

  6. SDSS-IV MaNGA: faint quenched galaxies - I. Sample selection and evidence for environmental quenching

    Science.gov (United States)

    Penny, Samantha J.; Masters, Karen L.; Weijmans, Anne-Marie; Westfall, Kyle B.; Bershady, Matthew A.; Bundy, Kevin; Drory, Niv; Falcón-Barroso, Jesús; Law, David; Nichol, Robert C.; Thomas, Daniel; Bizyaev, Dmitry; Brownstein, Joel R.; Freischlad, Gordon; Gaulme, Patrick; Grabowski, Katie; Kinemuchi, Karen; Malanushenko, Elena; Malanushenko, Viktor; Oravetz, Daniel; Roman-Lopes, Alexandre; Pan, Kaike; Simmons, Audrey; Wake, David A.

    2016-11-01

    Using kinematic maps from the Sloan Digital Sky Survey (SDSS) Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, we reveal that the majority of low-mass quenched galaxies exhibit coherent rotation in their stellar kinematics. Our sample includes all 39 quenched low-mass galaxies observed in the first year of MaNGA. The galaxies are selected with Mr > -19.1, stellar masses 109 M⊙ 1.9. They lie on the size-magnitude and σ-luminosity relations for previously studied dwarf galaxies. Just six (15 ± 5.7 per cent) are found to have rotation speeds ve, rot 5 × 1010 M⊙), supporting the hypothesis that galaxy-galaxy or galaxy-group interactions quench star formation in low-mass galaxies. The local bright galaxy density for our sample is ρproj = 8.2 ± 2.0 Mpc-2, compared to ρproj = 2.1 ± 0.4 Mpc-2 for a star-forming comparison sample, confirming that the quenched low-mass galaxies are preferentially found in higher density environments.

  7. Quench protection in superconducting magnets

    International Nuclear Information System (INIS)

    Shajii, A.; Freidberg, J.P.

    1993-01-01

    The purpose of this obviously non-plasma physics research is to demonstrate that many of the powerful and sophisticated theoretical techniques widely used by the plasma physics community can be applied to engineering problems of direct interest to the magnetic fusion program. Quench protection is such a problem. If a sudden pulse of energy is delivered (usually by accident) to a small section of a superconducting magnet, it may go normal. Under such conditions, the magnet current flows in the surrounding copper matrix, which is essentially in parallel with the superconductor. Although the copper is a good conductor, it still dissipates ohmic power, further adding to the energy input. It is important to detect the quench as early as possible in order to shut off the current, thereby preventing irreversible damage to the conductor. This a non-trivial problem since the cables comprising a coil can be as long as one kilometer. The theory presented here starts with a set of multi-dimensional Navier-Stokes and heat transport equations for the coupled system of helium coolant, superconducting/copper cable, and surrounding jacket. A combination of multiple time scale expansions and asymptotic analysis reduces the problem to a nonlinear fourth order system of 1-D plus time equations. A code has been written whose numerical results are in excellent agreement with more complex engineering codes. There is at least an order of magnitude savings in CPU over the existing codes where a typical run requires one hour Cray CPU. By investigating a number of different cases the authors have been able to introduce further analytic approximations which reduce the problem to quasi-analytic form, a set of three ODE's in time. The results here too are in excellent agreement with the engineering code and requires only several seconds of CPU time. More important, the critical dimensionless parameters have been identified, as well as practical scaling information for the magnet design

  8. Towards improved local hybrid functionals by calibration of exchange-energy densities

    International Nuclear Information System (INIS)

    Arbuznikov, Alexei V.; Kaupp, Martin

    2014-01-01

    A new approach for the calibration of (semi-)local and exact exchange-energy densities in the context of local hybrid functionals is reported. The calibration functions are derived from only the electron density and its spatial derivatives, avoiding spatial derivatives of the exact-exchange energy density or other computationally unfavorable contributions. The calibration functions fulfill the seven more important out of nine known exact constraints. It is shown that calibration improves substantially the definition of a non-dynamical correlation energy term for generalized gradient approximation (GGA)-based local hybrids. Moreover, gauge artifacts in the potential-energy curves of noble-gas dimers may be corrected by calibration. The developed calibration functions are then evaluated for a large range of energy-related properties (atomization energies, reaction barriers, ionization potentials, electron affinities, and total atomic energies) of three sets of local hybrids, using a simple one-parameter local-mixing. The functionals are based on (a) local spin-density approximation (LSDA) or (b) Perdew-Burke-Ernzerhof (PBE) exchange and correlation, and on (c) Becke-88 (B88) exchange and Lee-Yang-Parr (LYP) correlation. While the uncalibrated GGA-based functionals usually provide very poor thermochemical data, calibration allows a dramatic improvement, accompanied by only a small deterioration of reaction barriers. In particular, an optimized BLYP-based local-hybrid functional has been found that is a substantial improvement over the underlying global hybrids, as well as over previously reported LSDA-based local hybrids. It is expected that the present calibration approach will pave the way towards new generations of more accurate hyper-GGA functionals based on a local mixing of exchange-energy densities

  9. Quantum quenches to the attractive one-dimensional Bose gas: exact results

    Directory of Open Access Journals (Sweden)

    Lorenzo Piroli, Pasquale Calabrese, Fabian H. L. Essler

    2016-09-01

    Full Text Available We study quantum quenches to the one-dimensional Bose gas with attractive interactions in the case when the initial state is an ideal one-dimensional Bose condensate. We focus on properties of the stationary state reached at late times after the quench. This displays a finite density of multi-particle bound states, whose rapidity distribution is determined exactly by means of the quench action method. We discuss the relevance of the multi-particle bound states for the physical properties of the system, computing in particular the stationary value of the local pair correlation function $g_2$.

  10. MSFC Electrostatic Levitator (ESL) Rapid Quench System

    Science.gov (United States)

    SanSoucie, Michael P.; Craven, Paul D.; Rogers, Jan R.

    2014-01-01

    The NASA Marshall Space Flight Center (MSFC) Electrostatic Levitator (ESL) Laboratory is a unique facility for investigators studying high-temperature materials. The laboratory boasts two levitators in which samples can be levitated, heated, melted, undercooled, and resolidified, all without the interference of a container or data-gathering instrument. The ESL main chamber has been upgraded with the addition of a rapid quench system. This system allows samples to be dropped into a quench vessel that can be filled with a low melting point material, such as a gallium or indium alloy. Thereby allowing rapid quenching of undercooled liquid metals. Up to 8 quench vessels can be loaded into the quench wheel, which is indexed with LabVIEW control software. This allows up to 8 samples to be rapidly quenched before having to open the chamber. The system has been tested successfully on several zirconium samples. Future work will be done with other materials using different quench mediums. Microstructural analysis will also be done on successfully quench samples.

  11. Quantum quenches in the thermodynamic limit.

    Science.gov (United States)

    Rigol, M

    2014-05-02

    We introduce a linked-cluster based computational approach that allows one to study quantum quenches in lattice systems in the thermodynamic limit. This approach is used to study quenches in one-dimensional lattices. We provide evidence that, in the thermodynamic limit, thermalization occurs in the nonintegrable regime but fails at integrability. A phase transitionlike behavior separates the two regimes.

  12. Quenching and recovery experiments on tungsten

    International Nuclear Information System (INIS)

    Rasch, K.D.; Siegel, R.W.; Schultz, H.

    1976-01-01

    A short summary is given of new results concerning transmission electron microscopy and resistivity measurements on quenched tungsten. These results give evidence for the first time that the quenching and annealing of high purity tungsten leads to vacancy--defect clustering resulting in small voids observable in the electron microscope. 21 references

  13. Adjuvant irradiation improves the outcome of patients with rectal cancer following local excision

    International Nuclear Information System (INIS)

    Chakravarti, Arnab; Willett, Christopher G.; Shellito, Paul; Kaufman, Donald; Daley, William J.

    1997-01-01

    PURPOSE: the long-term outcomes of patients undergoing local excision with or without pelvic irradiation were examined to define the role of adjuvant irradiation following local excision of T1 and T2 rectal cancers. METHODS: From January 1966 to January 1997, 114 patients underwent local excision for rectal cancer. Fifty-nine patients underwent local excision alone, and 55 patients received adjuvant pelvic irradiation (45 Gy to 65.8 Gy)+/-concurrent 5-fluorouracil chemotherapy. Outcome was assessed by treatment, stage, and pathologic features of tumor grade and lymphatic/venous vessel involvement. RESULTS: Of the 114 patients treated by local excision, 90 had T1/T2 tumors. The 5-year actuarial local control (LC) and recurrence-free survival (RFS) of these 90 patients are shown (with numbers of patients at risk at 5 years) in the table below. The 5-year actuarial local control and recurrence-free survival (RFS) for T1/T2 patients treated by local excision alone was 85% and 77%, respectively. The corresponding values for patients undergoing local excision and adjuvant irradiation alone were 88% and 78%, respectively. All 20 patients treated by adjuvant chemoradiation achieved 5-year actuarial local control and had a recurrence-free survival of 88%. The improved outcomes in the adjuvant radiation group become more impressive when the higher T stage distribution of this group is considered. Fifty-five percent of the group receiving adjuvant radiation were stage T2 compared to only 14% of patients treated by local excision alone. Subgroup analysis was performed on those features recognized as poor prognostic factors including poorly differentiated histology and lymphatic vascular invasion. Patients in the local excision alone group with one or more adverse pathologic features had reduced rates of local control compared to those with the absence of such features (38% vs. 91%, respectively, p=0.02). In comparison, the 5 patients with poor prognostic features treated by

  14. Quench Heater Studies for the LHC Magnets

    CERN Document Server

    Rodríguez-Mateos, F

    2001-01-01

    About 2000 LHC (CERN's Large Hadron Collider) superconducting magnets will be protected with quench heaters against development of excessive voltage and overheating after a resistive transition. The quench heater strips are powered by capacitor bank discharge power supplies. The strips are made of stainless steel partially plated with copper to reduce their resistance and to allow for the connection of quench heaters in series. The strips are embedded in between two polyimide foils. The initial power density and the current decay time determine the quench heater effectiveness. Since only one type of heater power supply will be available, the copper plating cycle is adapted for the various magnet types to keep the resistance of the heater circuit constant. Different quench heater designs have been tested on various prototype magnets to optimise the copper-plating cycle and the electric insulation of the heater strip. This paper summarises the experimental results and computations that allowed to finalise the h...

  15. Doubly heavy baryons and quark-diquark symmetry in quenched and partially quenched chiral perturbation theory

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Mehen; Brian C. Tiburzi

    2006-07-17

    We extend the chiral Lagrangian with heavy quark-diquark symmetry to quenched and partially quenched theories. These theories are used to derive formulae for the chiral extrapolation of masses and hyperfine splittings of doubly heavy baryons in lattice QCD simulations. A quark-diquark symmetry prediction for the hyperfine splittings of heavy mesons and doubly heavy baryons is rather insensitive to chiral corrections in both quenched and partially quenched QCD. Extrapolation formulae for the doubly heavy baryon electromagnetic transition moments are also determined for the partially quenched theory.

  16. ELUCID. IV. Galaxy Quenching and its Relation to Halo Mass, Environment, and Assembly Bias

    Science.gov (United States)

    Wang, Huiyuan; Mo, H. J.; Chen, Sihan; Yang, Yang; Yang, Xiaohu; Wang, Enci; van den Bosch, Frank C.; Jing, Yipeng; Kang, Xi; Lin, Weipeng; Lim, S. H.; Huang, Shuiyao; Lu, Yi; Li, Shijie; Cui, Weiguang; Zhang, Youcai; Tweed, Dylan; Wei, Chengliang; Li, Guoliang; Shi, Feng

    2018-01-01

    We examine the quenched fraction of central and satellite galaxies as a function of galaxy stellar mass, halo mass, and the matter density of their large-scale environment. Matter densities are inferred from our ELUCID simulation, a constrained simulation of the local universe sampled by SDSS, while halo masses and central/satellite classification are taken from the galaxy group catalog of Yang et al. The quenched fraction for the total population increases systematically with the three quantities. We find that the “environmental quenching efficiency,” which quantifies the quenched fraction as a function of halo mass, is independent of stellar mass. And this independence is the origin of the stellar mass independence of density-based quenching efficiency found in previous studies. Considering centrals and satellites separately, we find that the two populations follow similar correlations of quenching efficiency with halo mass and stellar mass, suggesting that they have experienced similar quenching processes in their host halo. We demonstrate that satellite quenching alone cannot account for the environmental quenching efficiency of the total galaxy population, and that the difference between the two populations found previously arises mainly from the fact that centrals and satellites of the same stellar mass reside, on average, in halos of different mass. After removing these effects of halo mass and stellar mass, there remains a weak, but significant, residual dependence on environmental density, which is eliminated when halo assembly bias is taken into account. Our results therefore indicate that halo mass is the prime environmental parameter that regulates the quenching of both centrals and satellites.

  17. Improvement of observer performance during fluoroscopy by local adaptive contrast enhancement

    International Nuclear Information System (INIS)

    Gould, R.G.; Demas, B.E.; Maroney, T.P.

    1988-01-01

    The ability of a video processor (FluoroVision FV-1), which performs two-dimensional locally adaptive contrast enhancement, to improve the detection of a low-contrast object was evaluated by means of receiver operating characteristic (ROC) curves. Three independent observers viewed a videotape of 50 fluoroscopic images of a varied background, in which a test object was present in 25. Each observer viewed the tape under four conditions: (1) no processing, (2) temporal noise reduction (gaussian weighted time averaging, (3) contrast enhancement, and (4) both noise reduction and contrast enhancement. The results were that detection was significantly improved by the locally adaptive contrast enhancement. Noise reduction did not significantly improve performance, probably because washer detection was limited by background contrast variations as well as noise and because only a small amount of noise reduction was used. The authors conclude that the processing device is potentially valuable in improving the quality of clinical fluoroscopic images

  18. Bulky household waste management in a UK local authority area: current practice, challenges and improvement opportunities

    OpenAIRE

    Cole, C; Osmani, M; Wheatley, A; Quddus, M

    2013-01-01

    Charnwood Borough Council (CBC), an English local authority, recently introduced a Zero Waste Strategy encompassing targets for waste minimisation and recycling of household waste above UK Government baselines. To achieve these targets various areas of household waste management need to be amended to improve recycling performance. The bulky waste collection service, collecting large items such as furniture and electrical goods was identified as an area to target for improvement. A case study ...

  19. Detecting a many-body mobility edge with quantum quenches

    Directory of Open Access Journals (Sweden)

    Piero Naldesi, Elisa Ercolessi, Tommaso Roscilde

    2016-10-01

    Full Text Available The many-body localization (MBL transition is a quantum phase transition involving highly excited eigenstates of a disordered quantum many-body Hamiltonian, which evolve from "extended/ergodic" (exhibiting extensive entanglement entropies and fluctuations to "localized" (exhibiting area-law scaling of entanglement and fluctuations. The MBL transition can be driven by the strength of disorder in a given spectral range, or by the energy density at fixed disorder - if the system possesses a many-body mobility edge. Here we propose to explore the latter mechanism by using "quantum-quench spectroscopy", namely via quantum quenches of variable width which prepare the state of the system in a superposition of eigenstates of the Hamiltonian within a controllable spectral region. Studying numerically a chain of interacting spinless fermions in a quasi-periodic potential, we argue that this system has a many-body mobility edge; and we show that its existence translates into a clear dynamical transition in the time evolution immediately following a quench in the strength of the quasi-periodic potential, as well as a transition in the scaling properties of the quasi-stationary state at long times. Our results suggest a practical scheme for the experimental observation of many-body mobility edges using cold-atom setups.

  20. Improving the fiscal role of local taxes and fees in the formation of revenues of local budgets

    Directory of Open Access Journals (Sweden)

    Svitlana Mykhailenko

    2017-03-01

    Full Text Available Decentralization of power and a significant empowerment of local communities, the provision of fiscal autonomy and financial independence of local budgets, strengthening of material and financial base of local self-government is an objective need for Ukraine. In modern conditions of development of the state economy enhancing the role of local taxes and fees and an increase in the revenue part of local budgets at their expense is the main lever for increased financial independence and financial autonomy of local authorities. Local taxation system must provide local authorities with financial resources to fulfill its mandate. However, local governments are not able to fully satisfy their functions and tasks from local taxes and fees, which requires further research in this area. The aim of the article is to study the role of local taxes and fees in the formation of revenues of local budgets of Ukraine taking into account the innovations of the budget and tax legislation, and making proposals on the reform of local taxation system. The paper used the methods of theoretical and practical generalization, systematic and comparative analysis, statistical methods, grouping, table-graphics. The study reviewed the historical aspects of the formation and development of local taxes and fees in Ukraine, analyzed the innovation budget and tax legislation with respect to the local tax system, their positive and negative consequences. The analysis of the composition and structure of local taxes and fees in the incomes of local budgets of Ukraine for five years. The role of local taxes and fees in the local budget revenues, tax revenues and GDP. The measures to further reform the system of local taxes and fees in the country. Key words: incomes of local budgets, the system of local taxes and fees.

  1. Entropy of Isolated Quantum Systems after a Quench

    Science.gov (United States)

    Rigol, Marcos; Santos, Lea; Polkovnikov, Anatoli

    2012-02-01

    A diagonal entropy, which depends only on the diagonal elements of the system's density matrix in the energy representation, has been argued to be the proper definition of thermodynamic entropy in out-of-equilibrium quantum systems. We study this quantity after an interaction quench in lattice hardcore bosons and spinless fermions, and after a local chemical potential quench in a system of hard-core bosons in a superlattice potential. The former systems have a chaotic regime, where the diagonal entropy approaches the equilibrium microcanonical entropy, coinciding with the onset of thermalization. The latter system is integrable. We show that its diagonal entropy is additive and different from the entropy of a generalized Gibbs ensemble, which has been introduced to account for the effects of conserved quantities at integrability [1]. [4pt] [1] Lea F. Santos, Anatoli Polkovnikov, and Marcos Rigol, Phys. Rev. Lett. 107, 040601 (2011).

  2. Improving Elementary School Students’ English Vocabulary Through Local Cultural Content Materials

    Directory of Open Access Journals (Sweden)

    Frans Manurung

    2015-06-01

    Full Text Available Abstract Elementary students of a certain public school in Indonesia had difficulties in learning English. One of the crucial problems was learning English vocabulary. In an attempt to help the students learn and improve English vocabulary, the researchers decided to use CAR to teach English vocabulary with local cultural content materials. The aim of this study was to investigate how the teaching of English vocabulary with local cultural content materials contributed to the improvement of the students’ English vocabulary mastery. The topics covered in the materials were selected based on schemata theory. Vocabulary learning process was done through several activities provided in the materials: classroom and outside vocabulary learning. The results showed that the teaching of local cultural content materials have contributed to the improvement of the Elementary students’ vocabulary mastery. The schematic knowledge found in the familiar topics has aroused the students’ interest and motivation in learning English vocabulary. Students who were more familiar with the topics could respond to the vocabulary learning better than those who were not familiar with. The vocabulary mastery was more successful only if the students participated in both classroom and outside vocabulary learning process. Keywords: Vocabulary Mastery, Vocabulary Improvement, Local Cultural Content Materials, Vocabulary Learning, Schemata

  3. Localized probability of improvement for kriging based multi-objective optimization

    Science.gov (United States)

    Li, Yinjiang; Xiao, Song; Barba, Paolo Di; Rotaru, Mihai; Sykulski, Jan K.

    2017-12-01

    The paper introduces a new approach to kriging based multi-objective optimization by utilizing a local probability of improvement as the infill sampling criterion and the nearest neighbor check to ensure diversification and uniform distribution of Pareto fronts. The proposed method is computationally fast and linearly scalable to higher dimensions.

  4. IMPROVING THE LEARNING ENVIRONMENT, A STUDY ON THE LOCAL PREPARATION OF VISUAL INSTRUCTIONAL MATERIALS.

    Science.gov (United States)

    FARIS, GENE; AND OTHERS

    THIS INVESTIGATION DEVELOPED A GUIDE TO AID IN IMPROVING TEACHER EFFECTIVENESS. IT SHOULD ASSIST ADMINISTRATORS AND SUPERVISORS TO INITIATE AND EXPAND PROGRAMS FOR THE PRODUCTION OF VISUAL INSTRUCTIONAL MATERIALS. IT REPORTED ON THE NATIONAL STATUS OF LOCAL PROGRAMS DEVELOPED AND PROVIDED CASE STUDIES ON OUTSTANDING ONES. TEACHER OPINIONS AND…

  5. Automated linear regression tools improve RSSI WSN localization in multipath indoor environment

    Directory of Open Access Journals (Sweden)

    Laermans Eric

    2011-01-01

    Full Text Available Abstract Received signal strength indication (RSSI-based localization is emerging in wireless sensor networks (WSNs. Localization algorithms need to include the physical and hardware limitations of RSSI measurements in order to give more accurate results in dynamic real-life indoor environments. In this study, we use the Interdisciplinary Institute for Broadband Technology real-life test bed and present an automated method to optimize and calibrate the experimental data before offering them to a positioning engine. In a preprocessing localization step, we introduce a new method to provide bounds for the range, thereby further improving the accuracy of our simple and fast 2D localization algorithm based on corrected distance circles. A maximum likelihood algorithm with a mean square error cost function has a higher position error median than our algorithm. Our experiments further show that the complete proposed algorithm eliminates outliers and avoids any manual calibration procedure.

  6. IMPROVEMENT OF 3D MONTE CARLO LOCALIZATION USING A DEPTH CAMERA AND TERRESTRIAL LASER SCANNER

    Directory of Open Access Journals (Sweden)

    S. Kanai

    2015-05-01

    Full Text Available Effective and accurate localization method in three-dimensional indoor environments is a key requirement for indoor navigation and lifelong robotic assistance. So far, Monte Carlo Localization (MCL has given one of the promising solutions for the indoor localization methods. Previous work of MCL has been mostly limited to 2D motion estimation in a planar map, and a few 3D MCL approaches have been recently proposed. However, their localization accuracy and efficiency still remain at an unsatisfactory level (a few hundreds millimetre error at up to a few FPS or is not fully verified with the precise ground truth. Therefore, the purpose of this study is to improve an accuracy and efficiency of 6DOF motion estimation in 3D MCL for indoor localization. Firstly, a terrestrial laser scanner is used for creating a precise 3D mesh model as an environment map, and a professional-level depth camera is installed as an outer sensor. GPU scene simulation is also introduced to upgrade the speed of prediction phase in MCL. Moreover, for further improvement, GPGPU programming is implemented to realize further speed up of the likelihood estimation phase, and anisotropic particle propagation is introduced into MCL based on the observations from an inertia sensor. Improvements in the localization accuracy and efficiency are verified by the comparison with a previous MCL method. As a result, it was confirmed that GPGPU-based algorithm was effective in increasing the computational efficiency to 10-50 FPS when the number of particles remain below a few hundreds. On the other hand, inertia sensor-based algorithm reduced the localization error to a median of 47mm even with less number of particles. The results showed that our proposed 3D MCL method outperforms the previous one in accuracy and efficiency.

  7. Automatic block-matching registration to improve lung tumor localization during image-guided radiotherapy

    Science.gov (United States)

    Robertson, Scott Patrick

    To improve relatively poor outcomes for locally-advanced lung cancer patients, many current efforts are dedicated to minimizing uncertainties in radiotherapy. This enables the isotoxic delivery of escalated tumor doses, leading to better local tumor control. The current dissertation specifically addresses inter-fractional uncertainties resulting from patient setup variability. An automatic block-matching registration (BMR) algorithm is implemented and evaluated for the purpose of directly localizing advanced-stage lung tumors during image-guided radiation therapy. In this algorithm, small image sub-volumes, termed "blocks", are automatically identified on the tumor surface in an initial planning computed tomography (CT) image. Each block is independently and automatically registered to daily images acquired immediately prior to each treatment fraction. To improve the accuracy and robustness of BMR, this algorithm incorporates multi-resolution pyramid registration, regularization with a median filter, and a new multiple-candidate-registrations technique. The result of block-matching is a sparse displacement vector field that models local tissue deformations near the tumor surface. The distribution of displacement vectors is aggregated to obtain the final tumor registration, corresponding to the treatment couch shift for patient setup correction. Compared to existing rigid and deformable registration algorithms, the final BMR algorithm significantly improves the overlap between target volumes from the planning CT and registered daily images. Furthermore, BMR results in the smallest treatment margins for the given study population. However, despite these improvements, large residual target localization errors were noted, indicating that purely rigid couch shifts cannot correct for all sources of inter-fractional variability. Further reductions in treatment uncertainties may require the combination of high-quality target localization and adaptive radiotherapy.

  8. A method for improved clustering and classification of microscopy images using quantitative co-localization coefficients

    LENUS (Irish Health Repository)

    Singan, Vasanth R

    2012-06-08

    AbstractBackgroundThe localization of proteins to specific subcellular structures in eukaryotic cells provides important information with respect to their function. Fluorescence microscopy approaches to determine localization distribution have proved to be an essential tool in the characterization of unknown proteins, and are now particularly pertinent as a result of the wide availability of fluorescently-tagged constructs and antibodies. However, there are currently very few image analysis options able to effectively discriminate proteins with apparently similar distributions in cells, despite this information being important for protein characterization.FindingsWe have developed a novel method for combining two existing image analysis approaches, which results in highly efficient and accurate discrimination of proteins with seemingly similar distributions. We have combined image texture-based analysis with quantitative co-localization coefficients, a method that has traditionally only been used to study the spatial overlap between two populations of molecules. Here we describe and present a novel application for quantitative co-localization, as applied to the study of Rab family small GTP binding proteins localizing to the endomembrane system of cultured cells.ConclusionsWe show how quantitative co-localization can be used alongside texture feature analysis, resulting in improved clustering of microscopy images. The use of co-localization as an additional clustering parameter is non-biased and highly applicable to high-throughput image data sets.

  9. Quench-Induced Stresses in AA2618 Forgings for Impellers: A Multiphysics and Multiscale Problem

    Science.gov (United States)

    Chobaut, Nicolas; Saelzle, Peter; Michel, Gilles; Carron, Denis; Drezet, Jean-Marie

    2015-05-01

    In the fabrication of heat-treatable aluminum parts such as AA2618 compressor impellers for turbochargers, solutionizing and quenching are key steps to obtain the required mechanical characteristics. Fast quenching is necessary to avoid coarse precipitation as it reduces the mechanical properties obtained after heat treatment. However, fast quenching induces residual stresses that can cause unacceptable distortions during machining. Furthermore, the remaining residual stresses after final machining can lead to unfavorable stresses in service. Predicting and controlling internal stresses during the whole processing from heat treatment to final machining is therefore of particular interest to prevent negative impacts of residual stresses. This problem is multiphysics because processes such as heat transfer during quenching, precipitation phenomena, thermally induced deformations, and stress generation are interacting and need to be taken into account. The problem is also multiscale as precipitates of nanosize form during quenching at locations where the cooling rate is too low. This precipitation affects the local yield strength of the material and thus impacts the level of macroscale residual stresses. A thermomechanical model accounting for precipitation in a simple but realistic way is presented. Instead of modelling precipitation that occurs during quenching, the model parameters are identified using a limited number of tensile tests achieved after representative interrupted cooling paths in a Gleeble machine. The simulation results are compared with as-quenched residual stresses in a forging measured by neutron diffraction.

  10. Quenching phenomena in natural circulation loop

    Energy Technology Data Exchange (ETDEWEB)

    Umekawa, Hisashi; Ozawa, Mamoru [Kansai Univ., Osaka (Japan); Ishida, Naoki [Daihatsu Motor Company, Osaka (Japan)

    1995-09-01

    Quenching phenomena has been investigated experimentally using circulation loop of liquid nitrogen. During the quenching under natural circulation, the heat transfer mode changes from film boiling to nucleate boiling, and at the same time flux changes with time depending on the vapor generation rate and related two-phase flow characteristics. Moreover, density wave oscillations occur under a certain operating condition, which is closely related to the dynamic behavior of the cooling curve. The experimental results indicates that the occurrence of the density wave oscillation induces the deterioration of effective cooling of the heat surface in the film and the transition boiling regions, which results in the decrease in the quenching velocity.

  11. Quenching phenomena in natural circulation loop

    International Nuclear Information System (INIS)

    Umekawa, Hisashi; Ozawa, Mamoru; Ishida, Naoki

    1995-01-01

    Quenching phenomena has been investigated experimentally using circulation loop of liquid nitrogen. During the quenching under natural circulation, the heat transfer mode changes from film boiling to nucleate boiling, and at the same time flux changes with time depending on the vapor generation rate and related two-phase flow characteristics. Moreover, density wave oscillations occur under a certain operating condition, which is closely related to the dynamic behavior of the cooling curve. The experimental results indicates that the occurrence of the density wave oscillation induces the deterioration of effective cooling of the heat surface in the film and the transition boiling regions, which results in the decrease in the quenching velocity

  12. [Application of improved locally linear embedding algorithm in dimensionality reduction of cancer gene expression data].

    Science.gov (United States)

    Liu, Wenyuan; Wang, Chunlei; Wang, Baowen; Wang, Changwu

    2014-02-01

    Cancer gene expression data have the characteristics of high dimensionalities and small samples so it is necessary to perform dimensionality reduction of the data. Traditional linear dimensionality reduction approaches can not find the nonlinear relationship between the data points. In addition, they have bad dimensionality reduction results. Therefore a multiple weights locally linear embedding (LLE) algorithm with improved distance is introduced to perform dimensionality reduction in this study. We adopted an improved distance to calculate the neighbor of each data point in this algorithm, and then we introduced multiple sets of linearly independent local weight vectors for each neighbor, and obtained the embedding results in the low-dimensional space of the high-dimensional data by minimizing the reconstruction error. Experimental result showed that the multiple weights LLE algorithm with improved distance had good dimensionality reduction functions of the cancer gene expression data.

  13. Improving local air quality in cities: To tree or not to tree?

    International Nuclear Information System (INIS)

    Vos, Peter E.J.; Maiheu, Bino; Vankerkom, Jean; Janssen, Stijn

    2013-01-01

    Vegetation is often quoted as an effective measure to mitigate urban air quality problems. In this work we demonstrate by the use of computer models that the air quality effect of urban vegetation is more complex than implied by such general assumptions. By modelling a variety of real-life examples we show that roadside urban vegetation rather leads to increased pollutant concentrations than it improves the air quality, at least locally. This can be explained by the fact that trees and other types of vegetation reduce the ventilation that is responsible for diluting the traffic emitted pollutants. This aerodynamic effect is shown to be much stronger than the pollutant removal capacity of vegetation. Although the modelling results may be subject to a certain level of uncertainty, our results strongly indicate that the use of urban vegetation for alleviating a local air pollution hotspot is not expected to be a viable solution. Highlights: ► We model the impact of roadside urban vegetation on the local air quality. ► Vegetation in general lowers the wind speed thereby reducing the ventilation. ► In general roadside urban vegetation does not appear to decrease concentrations. ► Roadside urban trees have a pronounced detrimental effect on the local air quality. ► City planners and policy makers need to be better informed about this topic. -- Rather than improving the local air quality, our results suggest that roadside urban vegetation increases the pollutant concentrations at the footpath

  14. Stochastic seismic inversion based on an improved local gradual deformation method

    Science.gov (United States)

    Yang, Xiuwei; Zhu, Peimin

    2017-12-01

    A new stochastic seismic inversion method based on the local gradual deformation method is proposed, which can incorporate seismic data, well data, geology and their spatial correlations into the inversion process. Geological information, such as sedimentary facies and structures, could provide significant a priori information to constrain an inversion and arrive at reasonable solutions. The local a priori conditional cumulative distributions at each node of model to be inverted are first established by indicator cokriging, which integrates well data as hard data and geological information as soft data. Probability field simulation is used to simulate different realizations consistent with the spatial correlations and local conditional cumulative distributions. The corresponding probability field is generated by the fast Fourier transform moving average method. Then, optimization is performed to match the seismic data via an improved local gradual deformation method. Two improved strategies are proposed to be suitable for seismic inversion. The first strategy is that we select and update local areas of bad fitting between synthetic seismic data and real seismic data. The second one is that we divide each seismic trace into several parts and obtain the optimal parameters for each part individually. The applications to a synthetic example and a real case study demonstrate that our approach can effectively find fine-scale acoustic impedance models and provide uncertainty estimations.

  15. Audio-Visual Fusion for Sound Source Localization and Improved Attention

    International Nuclear Information System (INIS)

    Lee, Byoung Gi; Choi, Jong Suk; Yoon, Sang Suk; Choi, Mun Taek; Kim, Mun Sang; Kim, Dai Jin

    2011-01-01

    Service robots are equipped with various sensors such as vision camera, sonar sensor, laser scanner, and microphones. Although these sensors have their own functions, some of them can be made to work together and perform more complicated functions. AudioFvisual fusion is a typical and powerful combination of audio and video sensors, because audio information is complementary to visual information and vice versa. Human beings also mainly depend on visual and auditory information in their daily life. In this paper, we conduct two studies using audioFvision fusion: one is on enhancing the performance of sound localization, and the other is on improving robot attention through sound localization and face detection

  16. Improving scale invariant feature transform with local color contrastive descriptor for image classification

    Science.gov (United States)

    Guo, Sheng; Huang, Weilin; Qiao, Yu

    2017-01-01

    Image representation and classification are two fundamental tasks toward version understanding. Shape and texture provide two key features for visual representation and have been widely exploited in a number of successful local descriptors, e.g., scale invariant feature transform (SIFT), local binary pattern descriptor, and histogram of oriented gradient. Unlike these gradient-based descriptors, this paper presents a simple yet efficient local descriptor, named local color contrastive descriptor (LCCD), which captures the contrastive aspects among local regions or color channels for image representation. LCCD is partly inspired by the neural science facts that color contrast plays important roles in visual perception and there exist strong linkages between color and shape. We leverage f-divergence as a robust measure to estimate the contrastive features between different spatial locations and multiple channels. Our descriptor enriches local image representation with both color and contrast information. Due to that LCCD does not explore any gradient information, individual LCCD does not yield strong performance. But we verified experimentally that LCCD can compensate strongly SIFT. Extensive experimental results on image classification show that our descriptor improves the performance of SIFT substantially by combination on three challenging benchmarks, including MIT Indoor-67 database, SUN397, and PASCAL VOC 2007.

  17. Improved quantum-behaved particle swarm optimization with local search strategy

    Directory of Open Access Journals (Sweden)

    Maolong Xi

    2017-03-01

    Full Text Available Quantum-behaved particle swarm optimization, which was motivated by analysis of particle swarm optimization and quantum system, has shown compared performance in finding the optimal solutions for many optimization problems to other evolutionary algorithms. To address the problem of premature, a local search strategy is proposed to improve the performance of quantum-behaved particle swarm optimization. In proposed local search strategy, a super particle is presented which is a collection body of randomly selected particles’ dimension information in the swarm. The selected probability of particles in swarm is different and determined by their fitness values. To minimization problems, the fitness value of one particle is smaller; the selected probability is more and will contribute more information in constructing the super particle. In addition, in order to investigate the influence on algorithm performance with different local search space, four methods of computing the local search radius are applied in local search strategy and propose four variants of local search quantum-behaved particle swarm optimization. Empirical studies on a suite of well-known benchmark functions are undertaken in order to make an overall performance comparison among the proposed methods and other quantum-behaved particle swarm optimization. The simulation results show that the proposed quantum-behaved particle swarm optimization variants have better advantages over the original quantum-behaved particle swarm optimization.

  18. An improved tracking framework for ultrasound probe localization in image-guided radiosurgery

    Directory of Open Access Journals (Sweden)

    Ipsen Svenja

    2016-09-01

    Full Text Available Real-time target localization with ultrasound holds high potential for image guidance and motion compensation in radiosurgery due to its non-invasive image acquisition free from ionizing radiation. However, a two-step localization has to be performed when integrating ultrasound into the existing radiosurgery workflow. In addition to target localization inside the ultrasound volume, the probe itself has to be localized in order to transform the target position into treatment room coordinates. By adapting existing camera calibration tools, we have developed a method to extend the stereoscopic X-ray tracking system of a radiosurgery platform in order to locate objects such as marker geometries with six degrees of freedom. The calibration was performed with 0.1 mm reprojection error. By using the full area of the flat-panel detectors without pre-processing the extended software increased the tracking volume and resolution by up to 80%, substantially improving patient localization and marker detectability. Furthermore, marker-tracking showed sub-millimeter accuracy and rotational errors below 0.1°. This demonstrates that the developed extension framework can accurately localize marker geometries using an integrated X-ray system, establishing the link for the integration of real-time ultrasound image guidance into the existing system.

  19. Quench-Protection Strategies for HTS Superconductors

    National Research Council Canada - National Science Library

    Lawless, William N

    2005-01-01

    Assessments are made of four distinct strategies for the quench protection of HTS coils near 77 K - diamond-film insulation, cryovaristor current shunt, loaded Formvar insulation, and a sputtered ceramic insulation...

  20. Binding phenomena and fluorescence quenching. I: Descriptive quantum principles of fluorescence quenching using a supermolecule approach

    Science.gov (United States)

    Callis, Patrik R.

    2014-12-01

    Principal aspects of fluorescence and quenching are placed on an equal footing consistent with microscopic quantum concepts familiar to all who use fluorescence in the study of association of ligands with proteins. Quenching of fluorophores involved in determination of ligand binding to proteins is described in terms of generic quantum principles using a framework in which the fluorophore and quencher are together considered a “supermolecule”. Quenching then becomes just another form of internal conversion, which in turn leads to new language for defining “dynamic” and “static” quenching, for which there exist disparate definitions. The benefit of casting quenching in this manner, and citing relevant literature, has been to expand the vocabulary and mental imagery associated with quenching.

  1. Progress in improving provincial plans for nutrition through targeted technical assistance and local advocacy in Vietnam.

    Science.gov (United States)

    Harris, Jody; Nguyen, Phuong H; To, Quyen; Frongillo, Edward A; Menon, Purnima

    2016-12-01

    Vietnam has been decentralizing nutrition planning to provinces, which could help with local relevance and accountability. Assessment in 2009 found a continuing top-down approach, limited human capacity, and difficulty in integrating multiple sectors. Alive and Thrive (A&T) provided targeted assistance and capacity-building for 15 provincial plans for nutrition (PPNs). We aimed to (i) assess PPN content and quality improvements 2009-2014, and (ii) explain processes through which change occurred. Data consisted of interview-based assessments of provincial planning processes, annual PPN assessments, and tracking of A&T involvement. At endline, some provinces produced higher quality plans. Local planning skills improved, but capacity remained insufficient. Awareness of and support for nutrition improved, but some policy and legal environments were contradictory. Objectives were clearer, but use of data for planning remained inconsistent. Provinces became more proactive and creative, but remained constrained by slow approval processes and insufficient funding. Targeted assistance and local advocacy can improve decentralized planning, with success dependent on policy and programming contexts and ability to overcome constraints around capacity, investment, data use and remnants of centralized planning. We recommend strong engagement with planners at the national level to understand how to unblock major constraints; solutions must take into consideration the particular political, financial and administrative context. © The Author 2016. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

  2. A quenched c = 1 critical matrix model

    International Nuclear Information System (INIS)

    Qiu, Zongan; Rey, Soo-Jong.

    1990-12-01

    We study a variant of the Penner-Distler-Vafa model, proposed as a c = 1 quantum gravity: 'quenched' matrix model with logarithmic potential. The model is exactly soluble, and exhibits a two-cut branching as observed in multicritical unitary matrix models and multicut Hermitian matrix models. Using analytic continuation of the power in the conventional polynomial potential, we also show that both the Penner-Distler-Vafa model and our 'quenched' matrix model satisfy Virasoro algebra constraints

  3. Numerical and experimental investigation of quench process

    Energy Technology Data Exchange (ETDEWEB)

    Guer, C.H.; Tekkaya, A.E.; Oeztuerk, T. [Middle East Technical Univ., Ankara (Turkey)

    1996-12-31

    Numerical and experimental studies have been carried out to investigate the evolution of residual stresses in quenched components induced by temperature gradient and phase transformations. In the numerical analysis, a finite element model is implemented for predicting the temperature field, phase changes with their associated internal stresses in axisymmetrical steel components. The model is verified by several comparisons with other known numerical results. Case studies are performed to investigate the effects of the quench bath temperature and the specimen geometry. Specimen geometry has been analyzed by introducing a hole in a cylinder and varying hole diameter and its eccentricity. Experiments include microstructural examination and X-ray diffraction measurements of surface residual stresses. QUENCHING is a common manufacturing process to produce parts with reliable service properties. Long parts with small cross sections, those with nonsymmetrical shapes, and those with holes, deep keyways or grooves are difficult to quench without distortion or cracking. Especially in quenching of construction steels, the quench cracking risks and great deformation is often encountered. On the other hand, most serious residual stresses are from the differential cooling and the volume increase due to the phase transformations.

  4. The Improved Kriging Interpolation Algorithm for Local Underwater Terrain Based on Fractal Compensation

    Directory of Open Access Journals (Sweden)

    Pengyun Chen

    2014-01-01

    Full Text Available The interpolation-reconstruction of local underwater terrain using the underwater digital terrain map (UDTM is an important step for building an underwater terrain matching unit and directly affects the accuracy of underwater terrain matching navigation. The Kriging method is often used in terrain interpolation, but, with this method, the local terrain features are often lost. Therefore, the accuracy cannot meet the requirements of practical application. Analysis of the geographical features is performed on the basis of the randomness and self-similarity of underwater terrain. We extract the fractal features of local underwater terrain with the fractal Brownian motion model, compensating for the possible errors of the Kriging method with fractal theory. We then put forward an improved Kriging interpolation method based on this fractal compensation. Interpolation-reconstruction tests show that the method can simulate the real underwater terrain features well and that it has good usability.

  5. An improved solution of local window parameters setting for local singularity analysis based on Excel VBA batch processing technology

    Science.gov (United States)

    Zhang, Daojun; Cheng, Qiuming; Agterberg, Frits; Chen, Zhijun

    2016-03-01

    In this paper Excel VBA is used for batch calculation in Local Singularity Analysis (LSA), which is for the information extracting from different kinds of geoscience data. Capabilities and advantages of a new module called Batch Tool for Local Singularity Index Mapping (BTLSIM) are: (1) batch production of series of local singularity maps with different settings of local window size, shape and orientation parameters; (2) local parameter optimization based on statistical tests; and (3) provision of extra output layers describing how spatial changes induced by parameter optimization are related to spatial structure of the original input layers.

  6. Film Boiling on Downward Quenching Hemisphere of Varying Sizes

    Energy Technology Data Exchange (ETDEWEB)

    Chan S. Kim; Kune Y. Suh; Joy L. Rempe; Fan-Bill Cheung; Sang B. Kim

    2004-04-01

    Film boiling heat transfer coefficients for a downward-facing hemispherical surface are measured from the quenching tests in DELTA (Downward-boiling Experimental Laminar Transition Apparatus). Two test sections are made of copper to maintain low Biot numbers. The outer diameters of the hemispheres are 120 mm and 294 mm, respectively. The thickness of all the test sections is 30 mm. The effect of diameter on film boiling heat transfer is quantified utilizing results obtained from the test sections. The measured data are compared with the numerical predictions from laminar film boiling analysis. The measured heat transfer coefficients are found to be greater than those predicted by the conventional laminar flow theory on account of the interfacial wavy motion incurred by the Helmholtz instability. Incorporation of the wavy motion model considerably improves the agreement between the experimental and numerical results in terms of heat transfer coefficient. In addition, the interfacial wavy motion and the quenching process are visualized through a digital camera.

  7. Management of local stressors can improve the resilience of marine canopy algae to global stressors.

    Directory of Open Access Journals (Sweden)

    Elisabeth M A Strain

    Full Text Available Coastal systems are increasingly threatened by multiple local anthropogenic and global climatic stressors. With the difficulties in remediating global stressors, management requires alternative approaches that focus on local scales. We used manipulative experiments to test whether reducing local stressors (sediment load and nutrient concentrations can improve the resilience of foundation species (canopy algae along temperate rocky coastlines to future projected global climate stressors (high wave exposure, increasing sea surface temperature, which are less amenable to management actions. We focused on Fucoids (Cystoseira barbata along the north-western Adriatic coast in the Mediterranean Sea because of their ecological relevance, sensitivity to a variety of human impacts, and declared conservation priority. At current levels of sediment and nutrients, C. barbata showed negative responses to the simulated future scenarios of high wave exposure and increased sea surface temperature. However, reducing the sediment load increased the survival of C. barbata recruits by 90.24% at high wave exposure while reducing nutrient concentrations resulted in a 20.14% increase in the survival and enhanced the growth of recruited juveniles at high temperature. We conclude that improving water quality by reducing nutrient concentrations, and particularly the sediment load, would significantly increase the resilience of C. barbata populations to projected increases in climate stressors. Developing and applying appropriate targets for specific local anthropogenic stressors could be an effective management action to halt the severe and ongoing loss of key marine habitats.

  8. Management of Local Stressors Can Improve the Resilience of Marine Canopy Algae to Global Stressors

    Science.gov (United States)

    Strain, Elisabeth M. A.; van Belzen, Jim; van Dalen, Jeroen; Bouma, Tjeerd J.; Airoldi, Laura

    2015-01-01

    Coastal systems are increasingly threatened by multiple local anthropogenic and global climatic stressors. With the difficulties in remediating global stressors, management requires alternative approaches that focus on local scales. We used manipulative experiments to test whether reducing local stressors (sediment load and nutrient concentrations) can improve the resilience of foundation species (canopy algae along temperate rocky coastlines) to future projected global climate stressors (high wave exposure, increasing sea surface temperature), which are less amenable to management actions. We focused on Fucoids (Cystoseira barbata) along the north-western Adriatic coast in the Mediterranean Sea because of their ecological relevance, sensitivity to a variety of human impacts, and declared conservation priority. At current levels of sediment and nutrients, C. barbata showed negative responses to the simulated future scenarios of high wave exposure and increased sea surface temperature. However, reducing the sediment load increased the survival of C. barbata recruits by 90.24% at high wave exposure while reducing nutrient concentrations resulted in a 20.14% increase in the survival and enhanced the growth of recruited juveniles at high temperature. We conclude that improving water quality by reducing nutrient concentrations, and particularly the sediment load, would significantly increase the resilience of C. barbata populations to projected increases in climate stressors. Developing and applying appropriate targets for specific local anthropogenic stressors could be an effective management action to halt the severe and ongoing loss of key marine habitats. PMID:25807516

  9. Strategy development for improving competitiveness of a Chinese local convenience store Case of Suguo Co., Ltd

    OpenAIRE

    Wang, Xiang; Ju, Wei

    2014-01-01

    The topic of the thesis is improving the competitiveness of the case company. We will regard Suguo as the case compamy. We focused on a Chinese local convenience store, and compared it in four perspectives with an international convenience store which has already entered the Chinese market successfully. The four perspectives are market perspective, customer perspective, management perspective, and decorative style perspective. In addition, we created a strategic map on the basis of the consum...

  10. Improving Multi-Component Maintenance Acquisition with a Greedy Heuristic Local Algorithm

    Science.gov (United States)

    2013-04-01

    maintenance decision making. Stinson and Khumawala (1987) formulated a heuristics-based mixed integer linear program (MILP) model for a finite horizon...References Bertolini, M., & Bevilacqua, M. (2006). A combined goal programming – AHP approach to maintenance selection problem. Reliability Engineering...Improving Multi-Component Maintenance Acquisition With a Greedy Heuristic Local Algorithm 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER

  11. Improved Radio Frequency Identification Indoor Localization Method via Radial Basis Function Neural Network

    Directory of Open Access Journals (Sweden)

    Dongliang Guo

    2014-01-01

    Full Text Available Indoor localization technique has received much attention in recent years. Many techniques have been developed to solve the problem. Among the recent proposed methods, radio frequency identification (RFID indoor localization technology has the advantages of low-cost, noncontact, non-line-of-sight, and high precision. This paper proposed two radial basis function (RBF neural network based indoor localization methods. The RBF neural networks are trained to learn the mapping relationship between received signal strength indication values and position of objects. Traditional method used the received signal strength directly as the input of neural network; we added another input channel by taking the difference of the received signal strength, thus improving the reliability and precision of positioning. Fuzzy clustering is used to determine the center of radial basis function. In order to reduce the impact of signal fading due to non-line-of-sight and multipath transmission in indoor environment, we improved the Gaussian filter to process received signal strength values. The experimental results show that the proposed method outperforms the existing methods as well as improves the reliability and precision of the RFID indoor positioning system.

  12. Wave form of current quench during disruptions in tokamaks

    International Nuclear Information System (INIS)

    Sugihara, Masayoshi; Gribov, Yuri; Shimada, Michiya; Lukash, Victor; Kawano, Yasunori; Yoshino, Ryuji; Miki, Nobuharu; Ohmori, Junji; Khayrutdinov, Rustam

    2003-01-01

    The time dependence of the current decay during the current quench phase of disruptions, which can significantly influence the electro-magnetic force on the in-vessel components due to the induced eddy currents, is investigated using data obtained in JT-60U experiments in order to derive a relevant physics guideline for the predictive simulations of disruptions in ITER. It is shown that an exponential decay can fit the time dependence of current quench for discharges with large quench rate (fast current quench). On the other hand, for discharges with smaller quench rate (slow current quench), a linear decay can fit the time dependence of current quench better than exponential. (author)

  13. Improvement of traditional local rice varieties through induced mutations using nuclear techniques

    International Nuclear Information System (INIS)

    Pham Van Ro; Do Huu At

    2001-01-01

    'Improvement of local rice varieties for high yield, resistance to disease and insect pests (brown plant hopper and rice blast) and export quality through induced mutations for the Mekong Delta' started in 1993. After six years, it showed effecting on the field in the MD as well as at the south of Vietnam. TNDB-100 manifest very wide adaptation and yield stable variety. THDB is suitable for deepwater rice region, coastal area, where rice cultivation effected by acid sulphate and salinity conditions. Both varieties are good example for the method. Thank to good Co-operation from extension center from provinces, hundred classes of extension were organized to recommend to the farmers. And thank to the strongly supporting from IAEA so that nearly 400,000 ha of TNDB-100 occupied at the south of Vietnam as well as nearly 15,000 ha of THDB grown in the coastal as well as rainfed lowland rice areas at the South of Vietnam. To continue the rice improvement by this technique, seeds of six traditional local varieties were exposed under different dose of gamma rays to create new mutants. At present day hundred improved breeding lines were selected, a dozen of uniform lines were isolated and entranced the yield trail as well as regional testing program. From these improved varieties would be selected to contribute to the rice cultivation at the south of Vietnam in the next years. (author)

  14. Improvement of traditional local rice varieties through induced mutations using nuclear techniques

    Energy Technology Data Exchange (ETDEWEB)

    Pham Van Ro; Do Huu At [Cuu Long Delta Rice Research Institute (Viet Nam)

    2001-03-01

    'Improvement of local rice varieties for high yield, resistance to disease and insect pests (brown plant hopper and rice blast) and export quality through induced mutations for the Mekong Delta' started in 1993. After six years, it showed effecting on the field in the MD as well as at the south of Vietnam. TNDB-100 manifest very wide adaptation and yield stable variety. THDB is suitable for deepwater rice region, coastal area, where rice cultivation effected by acid sulphate and salinity conditions. Both varieties are good example for the method. Thank to good Co-operation from extension center from provinces, hundred classes of extension were organized to recommend to the farmers. And thank to the strongly supporting from IAEA so that nearly 400,000 ha of TNDB-100 occupied at the south of Vietnam as well as nearly 15,000 ha of THDB grown in the coastal as well as rainfed lowland rice areas at the South of Vietnam. To continue the rice improvement by this technique, seeds of six traditional local varieties were exposed under different dose of gamma rays to create new mutants. At present day hundred improved breeding lines were selected, a dozen of uniform lines were isolated and entranced the yield trail as well as regional testing program. From these improved varieties would be selected to contribute to the rice cultivation at the south of Vietnam in the next years. (author)

  15. Quantum Quenches and Relaxation Dynamics in the Thermodynamic Limit

    Science.gov (United States)

    Mallayya, Krishnanand; Rigol, Marcos

    2018-02-01

    We implement numerical linked cluster expansions (NLCEs) to study dynamics of lattice systems following quantum quenches, and focus on a hard-core boson model in one-dimensional lattices. We find that, in the nonintegrable regime and within the accessible times, local observables exhibit exponential relaxation. We determine the relaxation rate as one departs from the integrable point and show that it scales quadratically with the strength of the integrability breaking perturbation. We compare the NLCE results with those from exact diagonalization calculations on finite chains with periodic boundary conditions, and show that NLCEs are far more accurate.

  16. CANDELS Sheds Light on the Environmental Quenching of Low-mass Galaxies

    Science.gov (United States)

    Guo, Yicheng; Bell, Eric F.; Lu, Yu; Koo, David C.; Faber, Sandra M.; CANDELS

    2018-01-01

    We investigate the environmental quenching of galaxies, especially those with stellar masses (M*) smaller than 10^9.5 M⊙, beyond the local universe. Essentially all local low-mass quenched galaxies (QGs) are believed to live close to massive central galaxies, which is a demonstration of environmental quenching. We use CANDELS data to test whether or not such a dwarf QG--massive central galaxy connection exists beyond the local universe. For this purpose, we only need a statistically representative, rather than a complete, sample of low-mass galaxies, which enables our study out to z > 1.5. For each low-mass galaxy, we measure the projected distance (dproj) to its nearest massive (M* > 10^10.5 M⊙) neighbor within a redshift range. At a given z and M*, the environmental quenching effect is considered to be observed if the dproj distribution of QGs is significantly skewed toward lower values than that of star-forming galaxies (SFGs). For galaxies with 10^8 M⊙ distributions of quenched and star-forming populations is detected up to z ˜ 1. Also, about 10% of the quenched galaxies in our sample are located between two and four virial radii (R_Vir) of the massive halos. The median projected distance from low-mass QGs to their massive neighbors (dproj/R_Vir) decreases with satellite M* at M* 10^9.5 M⊙. This trend suggests a smooth, if any, transition of the quenching timescale around M* of 10^9.5 M⊙ at 0.5 < z < 1.0.

  17. Effects of quenching and partial quenching on QCD penguin matrix elements

    NARCIS (Netherlands)

    Golterman, Maarten; Pallante, Elisabetta

    2002-01-01

    We point out that chiral transformation properties of penguin operators change in the transition from unquenched to (partially) quenched QCD. The way in which this affects the lattice determination of weak matrix elements can be understood in the framework of (partially) quenched chiral perturbation

  18. Fusing Bluetooth Beacon Data with Wi-Fi Radiomaps for Improved Indoor Localization

    Science.gov (United States)

    Kanaris, Loizos; Kokkinis, Akis; Liotta, Antonio; Stavrou, Stavros

    2017-01-01

    Indoor user localization and tracking are instrumental to a broad range of services and applications in the Internet of Things (IoT) and particularly in Body Sensor Networks (BSN) and Ambient Assisted Living (AAL) scenarios. Due to the widespread availability of IEEE 802.11, many localization platforms have been proposed, based on the Wi-Fi Received Signal Strength (RSS) indicator, using algorithms such as K-Nearest Neighbour (KNN), Maximum A Posteriori (MAP) and Minimum Mean Square Error (MMSE). In this paper, we introduce a hybrid method that combines the simplicity (and low cost) of Bluetooth Low Energy (BLE) and the popular 802.11 infrastructure, to improve the accuracy of indoor localization platforms. Building on KNN, we propose a new positioning algorithm (dubbed i-KNN) which is able to filter the initial fingerprint dataset (i.e., the radiomap), after considering the proximity of RSS fingerprints with respect to the BLE devices. In this way, i-KNN provides an optimised small subset of possible user locations, based on which it finally estimates the user position. The proposed methodology achieves fast positioning estimation due to the utilization of a fragment of the initial fingerprint dataset, while at the same time improves positioning accuracy by minimizing any calculation errors. PMID:28394268

  19. Fusing Bluetooth Beacon Data with Wi-Fi Radiomaps for Improved Indoor Localization.

    Science.gov (United States)

    Kanaris, Loizos; Kokkinis, Akis; Liotta, Antonio; Stavrou, Stavros

    2017-04-10

    Indoor user localization and tracking are instrumental to a broad range of services and applications in the Internet of Things (IoT) and particularly in Body Sensor Networks (BSN) and Ambient Assisted Living (AAL) scenarios. Due to the widespread availability of IEEE 802.11, many localization platforms have been proposed, based on the Wi-Fi Received Signal Strength (RSS) indicator, using algorithms such as K -Nearest Neighbour (KNN), Maximum A Posteriori (MAP) and Minimum Mean Square Error (MMSE). In this paper, we introduce a hybrid method that combines the simplicity (and low cost) of Bluetooth Low Energy (BLE) and the popular 802.11 infrastructure, to improve the accuracy of indoor localization platforms. Building on KNN, we propose a new positioning algorithm (dubbed i-KNN) which is able to filter the initial fingerprint dataset (i.e., the radiomap), after considering the proximity of RSS fingerprints with respect to the BLE devices. In this way, i-KNN provides an optimised small subset of possible user locations, based on which it finally estimates the user position. The proposed methodology achieves fast positioning estimation due to the utilization of a fragment of the initial fingerprint dataset, while at the same time improves positioning accuracy by minimizing any calculation errors.

  20. Fusing Bluetooth Beacon Data with Wi-Fi Radiomaps for Improved Indoor Localization

    Directory of Open Access Journals (Sweden)

    Loizos Kanaris

    2017-04-01

    Full Text Available Indoor user localization and tracking are instrumental to a broad range of services and applications in the Internet of Things (IoT and particularly in Body Sensor Networks (BSN and Ambient Assisted Living (AAL scenarios. Due to the widespread availability of IEEE 802.11, many localization platforms have been proposed, based on the Wi-Fi Received Signal Strength (RSS indicator, using algorithms such as K-Nearest Neighbour (KNN, Maximum A Posteriori (MAP and Minimum Mean Square Error (MMSE. In this paper, we introduce a hybrid method that combines the simplicity (and low cost of Bluetooth Low Energy (BLE and the popular 802.11 infrastructure, to improve the accuracy of indoor localization platforms. Building on KNN, we propose a new positioning algorithm (dubbed i-KNN which is able to filter the initial fingerprint dataset (i.e., the radiomap, after considering the proximity of RSS fingerprints with respect to the BLE devices. In this way, i-KNN provides an optimised small subset of possible user locations, based on which it finally estimates the user position. The proposed methodology achieves fast positioning estimation due to the utilization of a fragment of the initial fingerprint dataset, while at the same time improves positioning accuracy by minimizing any calculation errors.

  1. Quench behavior of a superconducting accelerator magnet

    International Nuclear Information System (INIS)

    McInturff, A.D.; Sampson, W.B.; Garber, M.; Dahl, P.F.

    1980-01-01

    Data are presented on the minimum energy required to cause quenches to propagate in an accelerator dipole magnet. The amount of stored energy dissipated into the magnet was measured as a function of dipole excitation current. This in turn determines the maximum coil temperature reached in a given magnet. Quench velocities in the longitudinal direction of the conductor were as high as 11m/sec. The azimuthal velocities or turn to turn velocities were found to be a function of the number of fiberglass layers of insulation that the quench had to cross and were on the order of a few tens of centimeters/sec. The field shape of a given magnet was found to be unchanged for more than 100 quenches. The coil to coil connection and inter-coil splice resistances were found to be less than a namo-ohm and therefore of litle consequence in the cryogenic load considerations. No definitive answers were found on how to decrease the rate of training (130 Gauss/Quench average) required from 4.OT to 5.1T

  2. An Improved Local Gradient Method for Sea Surface Wind Direction Retrieval from SAR Imagery

    Directory of Open Access Journals (Sweden)

    Lizhang Zhou

    2017-06-01

    Full Text Available Sea surface wind affects the fluxes of energy, mass and momentum between the atmosphere and ocean, and therefore regional and global weather and climate. With various satellite microwave sensors, sea surface wind can be measured with large spatial coverage in almost all-weather conditions, day or night. Like any other remote sensing measurements, sea surface wind measurement is also indirect. Therefore, it is important to develop appropriate wind speed and direction retrieval models for different types of microwave instruments. In this paper, a new sea surface wind direction retrieval method from synthetic aperture radar (SAR imagery is developed. In the method, local gradients are computed in frequency domain by combining the operation of smoothing and computing local gradients in one step to simplify the process and avoid the difference approximation. This improved local gradients (ILG method is compared with the traditional two-dimensional fast Fourier transform (2D FFT method and local gradients (LG method, using interpolating wind directions from the European Centre for Medium-Range Weather Forecast (ECMWF reanalysis data and the Cross-Calibrated Multi-Platform (CCMP wind vector product. The sensitivities to the salt-and-pepper noise, the additive noise and the multiplicative noise are analyzed. The ILG method shows a better performance of retrieval wind directions than the other two methods.

  3. Accuracy improvement in the TDR-based localization of water leaks

    Directory of Open Access Journals (Sweden)

    Andrea Cataldo

    Full Text Available A time domain reflectometry (TDR-based system for the localization of water leaks has been recently developed by the authors. This system, which employs wire-like sensing elements to be installed along the underground pipes, has proven immune to the limitations that affect the traditional, acoustic leak-detection systems.Starting from the positive results obtained thus far, in this work, an improvement of this TDR-based system is proposed. More specifically, the possibility of employing a low-cost, water-absorbing sponge to be placed around the sensing element for enhancing the accuracy in the localization of the leak is addressed.To this purpose, laboratory experiments were carried out mimicking a water leakage condition, and two sensing elements (one embedded in a sponge and one without sponge were comparatively used to identify the position of the leak through TDR measurements. Results showed that, thanks to the water retention capability of the sponge (which maintains the leaked water more localized, the sensing element embedded in the sponge leads to a higher accuracy in the evaluation of the position of the leak. Keywords: Leak localization, TDR, Time domain reflectometry, Water leaks, Underground water pipes

  4. Assessment of existing local houses condition as analysis tools for shore housing improvement program in Weriagar district, Bintuni Bay

    Science.gov (United States)

    Firmansyah, F.; Fernando, A.; Allo, I. P. R.

    2018-01-01

    The housing assessment is a part of the pre-feasibility study inThe Shore Housing Improvement Program in Weriagar District, West Papua. The housing assessment was conducted to identify the physical condition of existing houses. The parameters of assessment formulated from local references, practices and also national building regulation that covers each building system components, such as building structure/frame, building floor, building cover, and building roof. This study aims to explains lessons from local practices and references, used as the formula to generate assessment parameter, elaborate with Indonesia building regulation. The result of housing assessment were used as a basis to develop the house improvement strategy, the design alternative for housing improvement and further planning recommendations. The local knowledges involved in housing improvement program expected that the local-based approach could respect to the local build culture, respect the local environment, and the most important can offer best suitable solutions for functional utility and livability.

  5. Implicit time-dependent finite different algorithm for quench simulation

    Energy Technology Data Exchange (ETDEWEB)

    Koizumi, Norikiyo; Takahashi, Yoshikazu; Tsuji, Hiroshi [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    1994-12-01

    A magnet in a fusion machine has many difficulties in its application because of requirement of a large operating current, high operating field and high breakdown voltage. A cable-in-conduit (CIC) conductor is the best candidate to overcome these difficulties. However, there remained uncertainty in a quench event in the cable-in-conduit conductor because of a difficulty to analyze a fluid dynamics equation. Several scientists, then, developed the numerical code for the quench simulation. However, most of them were based on an explicit time-dependent finite difference scheme. In this scheme, a discrete time increment is strictly restricted by CFL (Courant-Friedrichs-Lewy) condition. Therefore, long CPU time was consumed for the quench simulation. Authors, then, developed a new quench simulation code, POCHI1, which is based on an implicit time dependent scheme. In POCHI1, the fluid dynamics equation is linearlized according to a procedure applied by Beam and Warming and then, a tridiagonal system can be offered. Therefore, no iteration is necessary to solve the fluid dynamics equation. This leads great reduction of the CPU time. Also, POCHI1 can cope with non-linear boundary condition. In this study, comparison with experimental results was carried out. The normal zone propagation behavior was investigated in two samples of CIC conductors which had different hydraulic diameters. The measured and simulated normal zone propagation length showed relatively good agreement. However, the behavior of the normal voltage shows a little disagreement. These results indicate necessity to improve the treatment of the heat transfer coefficient in the turbulent flow region and the electric resistivity of the copper stabilizer in high temperature and high field region. (author).

  6. Implicit time-dependent finite different algorithm for quench simulation

    International Nuclear Information System (INIS)

    Koizumi, Norikiyo; Takahashi, Yoshikazu; Tsuji, Hiroshi

    1994-12-01

    A magnet in a fusion machine has many difficulties in its application because of requirement of a large operating current, high operating field and high breakdown voltage. A cable-in-conduit (CIC) conductor is the best candidate to overcome these difficulties. However, there remained uncertainty in a quench event in the cable-in-conduit conductor because of a difficulty to analyze a fluid dynamics equation. Several scientists, then, developed the numerical code for the quench simulation. However, most of them were based on an explicit time-dependent finite difference scheme. In this scheme, a discrete time increment is strictly restricted by CFL (Courant-Friedrichs-Lewy) condition. Therefore, long CPU time was consumed for the quench simulation. Authors, then, developed a new quench simulation code, POCHI1, which is based on an implicit time dependent scheme. In POCHI1, the fluid dynamics equation is linearlized according to a procedure applied by Beam and Warming and then, a tridiagonal system can be offered. Therefore, no iteration is necessary to solve the fluid dynamics equation. This leads great reduction of the CPU time. Also, POCHI1 can cope with non-linear boundary condition. In this study, comparison with experimental results was carried out. The normal zone propagation behavior was investigated in two samples of CIC conductors which had different hydraulic diameters. The measured and simulated normal zone propagation length showed relatively good agreement. However, the behavior of the normal voltage shows a little disagreement. These results indicate necessity to improve the treatment of the heat transfer coefficient in the turbulent flow region and the electric resistivity of the copper stabilizer in high temperature and high field region. (author)

  7. Implementing and evaluating e-communication to improve intersectoral cooperation between hospitals and local communities

    DEFF Research Database (Denmark)

    Nicolaisen, Anne; Qvist, Peter

    2015-01-01

    in-between the two health care sectors. The initiative was initiated in 2009 and the quality standards are continuously revised. Aim: To evaluate to which degree the specified quality standards have been complied. Method: An explicit audit performed in all local municipalities and at selected...... it in an electronic form. Data will be analysed at the regional Centre for Quality. Results from each hospital and the municipalities will be presented at local audit meetings, in which challenges and initiatives to address those are discussed and further actions are decided. Results: The audit is ongoing......Background: There has been an increased focus on how to improve the quality of care to patients, which receives services from more than one provider in the health care system. An important factor is rapid and timely exchange of communication between hospitals and municipalities that provides...

  8. Efficient Fault Localization and Failure Analysis Techniques for Improving IC Yield

    Directory of Open Access Journals (Sweden)

    Ankush Oberai

    2018-02-01

    Full Text Available With the increase in the complexity of the semiconductor device processes and increase in the challenge to satisfy high market demands, enhancement in yield has become a crucial factor. Discovering and reacting to yield problems emerging at the end of the production line may cause unbearable yield loss leading to larger times to market. Thus, time and cost involved in fault isolation may be significantly shortened by effectively utilizing the fault diagnosis technology and supporting yield improvements. Hence for yield analysis, a highly integrated data network with software analysis tools have been established to reduce the fault analysis time. Synopsys Avalon, a product used for fault localization is described in this paper which aids in achieving better integrated circuit yields. This paper also illustrates various fault localization techniques for faster problem identification and discusses a few analytical tools like photon emission microscope and transmission emission microscope for faster determination of device failures.

  9. ESLpred2: improved method for predicting subcellular localization of eukaryotic proteins

    Directory of Open Access Journals (Sweden)

    Raghava Gajendra PS

    2008-11-01

    Full Text Available Abstract Background The expansion of raw protein sequence databases in the post genomic era and availability of fresh annotated sequences for major localizations particularly motivated us to introduce a new improved version of our previously forged eukaryotic subcellular localizations prediction method namely "ESLpred". Since, subcellular localization of a protein offers essential clues about its functioning, hence, availability of localization predictor would definitely aid and expedite the protein deciphering studies. However, robustness of a predictor is highly dependent on the superiority of dataset and extracted protein attributes; hence, it becomes imperative to improve the performance of presently available method using latest dataset and crucial input features. Results Here, we describe augmentation in the prediction performance obtained for our most popular ESLpred method using new crucial features as an input to Support Vector Machine (SVM. In addition, recently available, highly non-redundant dataset encompassing three kingdoms specific protein sequence sets; 1198 fungi sequences, 2597 from animal and 491 plant sequences were also included in the present study. First, using the evolutionary information in the form of profile composition along with whole and N-terminal sequence composition as an input feature vector of 440 dimensions, overall accuracies of 72.7, 75.8 and 74.5% were achieved respectively after five-fold cross-validation. Further, enhancement in performance was observed when similarity search based results were coupled with whole and N-terminal sequence composition along with profile composition by yielding overall accuracies of 75.9, 80.8, 76.6% respectively; best accuracies reported till date on the same datasets. Conclusion These results provide confidence about the reliability and accurate prediction of SVM modules generated in the present study using sequence and profile compositions along with similarity search

  10. Development of an improved local-ingredient-based complementary food and technology transfer to rural housewives.

    Science.gov (United States)

    Ouédraogo, Hermann Z; Traoré, Tahirou; Zèba, Augustin; Tiemtoré, Saïdou; Dramaix-Wilmet, Michèle; Hennart, Philippe; Donnen, Philippe

    2009-06-01

    Food technology transfer to rural households, based on local ingredients, is a relevant and sustainable strategy to ensure better nutrition of young children. Objective. To develop an improved mush based on local ingredients and evaluate the potential for transferring its technology to rural housewives. We developed a flour-based food using Alicom software and performed laboratory trials to evaluate its actual nutritional quality. Then we recruited housewives from each of the 27 project villages and trained them in flour production and mush preparation twice daily, 6 days a week, for 26 weeks. Mush was sampled during the training session and at weeks 4, 12, and 22 and evaluated for actual flow distance and dry matter content, which served to estimate energy density and iron and zinc contents. The laboratory trials reported average energy densities of 103 kcal/l00 g, iron contents of 2.6 mg/100 kcal, and zinc contents of 1.2 mg/100 kcal. The average (+/- SD) energy densities of the mush samples obtained during the training session and at weeks 4, 12, and 22 were 103.0 +/- 5.6, 103.3 +/- 5.2, 107.9 +/- 11.5, and 101.3 +/- 8.7 kcal/100 g, respectively. The average iron contents were 2.3 +/- 0.5, 2.3 +/- 0.5, 2.6 +/- 0.3, and 1.8 +/- 0.8 mg/ 100 kcal, respectively, and the average zinc contents were 1.6 +/- 0.1, 1.6 +/- 0.1, 1.7 +/- 0.1, and 1.6 +/- 0.2 mg/100 kcal. Developing a suitable complementary food from local ingredients and educating households in nutrition and use of local products are feasible. Such education should come with measures aimed at improving the accessibility of some ingredients to ensure feasibility and sustainability.

  11. Improving the early presentation of cancer symptoms in disadvantaged communities: putting local people in control.

    Science.gov (United States)

    Lyon, D; Knowles, J; Slater, B; Kennedy, R

    2009-12-03

    Premature deaths from cancer affect deprived communities disproportionately. The Department of Health has funded a programme in 19 Spearhead PCTs, delivered by the Improvement Foundation, to promote the early presentation and diagnosis of breast, bowel and lung cancers, with the ultimate intention of improving outcomes. The programme uses improvement methodology and is a unique approach involving local people working in partnership in their communities to raise awareness of cancer symptoms and promote early presentation. The teams work with primary care, other statutory organisations and with the voluntary sector. The specific contribution of the local people has been in the identification of hard-to-reach groups and the tailoring of effective health messages. Interim results show an increase in the number of urgent 2-week referrals and the proportion of new cancer cases diagnosed through the urgent 2-week referral route (from 43% to 51%) for all three cancers. These results were statistically significant for the bowel cancer and lung cancer pathways. There was also an increase in the proportion with no spread at the time of diagnosis for bowel cancer (38-43%) and breast cancer (41-44.5%), but these results did not reach statistical significance. This programme, helping community volunteers to lead work on raising awareness and promotion of earlier presentation of cancer symptoms in partnership with primary care and other professionals, is delivering positive early results.

  12. Structure of partly quenched molten copper chloride

    International Nuclear Information System (INIS)

    Pastore, G.; Tosi, M.P.

    1995-09-01

    The structural modifications induced in a model of molten CuCl by quenching the chlorine component into a microporous disordered matrix are evaluated using the hypernetted-chain closure in Ornstein-Zernike relations for the pair distribution functions in random systems. Aside from obvious changes in the behaviour of long-wavelength density fluctuations, the main effect of partial quenching is an enhanced delocalization of the Cu + ions. The model suggests that the ionic mobility in a superionic glass is enhanced relative to the melt at the same temperature and density. Only very minor quantitative differences are found in the structural functions when the replica Ornstein-Zernike relations derived by Given and Stell for a partly quenched system are simplified to those given earlier by Madden and Glandt. (author). 19 refs, 6 figs

  13. Dynamical quenching of tunneling in molecular magnets

    International Nuclear Information System (INIS)

    José Santander, María; Nunez, Alvaro S.; Roldán-Molina, A.; Troncoso, Roberto E.

    2015-01-01

    It is shown that a single molecular magnet placed in a rapidly oscillating magnetic field displays the phenomenon of quenching of tunneling processes. The results open a way to manipulate the quantum states of molecular magnets by means of radiation in the terahertz range. Our analysis separates the time evolution into slow and fast components thereby obtaining an effective theory for the slow dynamics. This effective theory presents quenching of the tunnel effect, in particular, stands out its difference with the so-called coherent destruction of tunneling. We support our prediction with numerical evidence based on an exact solution of Schrödinger's equation. - Highlights: • Single molecular magnets under rapidly oscillating magnetic fields is studied. • It is shown that this system displays the quenching of tunneling processes. • Our findings provide a control of quantum molecular magnets via terahertz radiation

  14. Thermal quench at finite 't Hooft coupling

    Directory of Open Access Journals (Sweden)

    H. Ebrahim

    2016-03-01

    Full Text Available Using holography we have studied thermal electric field quench for infinite and finite 't Hooft coupling constant. The set-up we consider here is D7-brane embedded in (α′ corrected AdS-black hole background. It is well-known that due to a time-dependent electric field on the probe brane, a time-dependent current will be produced and it will finally relax to its equilibrium value. We have studied the effect of different parameters of the system on equilibration time. As the most important results, for massless fundamental matter, we have observed a universal behaviour in the rescaled equilibration time in the very fast quench regime for different values of the temperature and α′ correction parameter. It seems that in the slow quench regime the system behaves adiabatically. We have also observed that the equilibration time decreases in finite 't Hooft coupling limit.

  15. Adaptation and implementation of local maternity dashboards in a Zimbabwean hospital to drive clinical improvement.

    Science.gov (United States)

    Crofts, J; Moyo, J; Ndebele, W; Mhlanga, S; Draycott, T; Sibanda, T

    2014-02-01

    The Commission on Information and Accountability for Women's and Children's Health of the World Health Organization (WHO) reported that national health outcome data were often of questionable quality and "not timely enough for practical use by health planners and administrators". Delayed reporting of poor-quality data limits the ability of front-line staff to identify problems rapidly and make improvements. Clinical "dashboards" based on locally available data offer a way of providing accurate and timely information. A dashboard is a simple computerized tool that presents a health facility's clinical data graphically using a traffic-light coding system to alert front-line staff about changes in the frequency of clinical outcomes. It provides rapid feedback on local outcomes in an accessible form and enables problems to be detected early. Until now, dashboards have been used only in high-resource settings. An overview maternity dashboard and a maternal mortality dashboard were designed for, and introduced at, a public hospital in Zimbabwe. A midwife at the hospital was trained to collect and input data monthly. Implementation of the maternity dashboards was feasible and 28 months of clinical outcome data were summarized using common computer software. Presentation of these data to staff led to the rapid identification of adverse trends in outcomes and to suggestions for actions to improve health-care quality. Implementation of maternity dashboards was feasible in a low-resource setting and resulted in actions that improved health-care quality locally. Active participation of hospital management and midwifery staff was crucial to their success.

  16. An Improved Otsu Threshold Segmentation Method for Underwater Simultaneous Localization and Mapping-Based Navigation

    Directory of Open Access Journals (Sweden)

    Xin Yuan

    2016-07-01

    Full Text Available The main focus of this paper is on extracting features with SOund Navigation And Ranging (SONAR sensing for further underwater landmark-based Simultaneous Localization and Mapping (SLAM. According to the characteristics of sonar images, in this paper, an improved Otsu threshold segmentation method (TSM has been developed for feature detection. In combination with a contour detection algorithm, the foreground objects, although presenting different feature shapes, are separated much faster and more precisely than by other segmentation methods. Tests have been made with side-scan sonar (SSS and forward-looking sonar (FLS images in comparison with other four TSMs, namely the traditional Otsu method, the local TSM, the iterative TSM and the maximum entropy TSM. For all the sonar images presented in this work, the computational time of the improved Otsu TSM is much lower than that of the maximum entropy TSM, which achieves the highest segmentation precision among the four above mentioned TSMs. As a result of the segmentations, the centroids of the main extracted regions have been computed to represent point landmarks which can be used for navigation, e.g., with the help of an Augmented Extended Kalman Filter (AEKF-based SLAM algorithm. The AEKF-SLAM approach is a recursive and iterative estimation-update process, which besides a prediction and an update stage (as in classical Extended Kalman Filter (EKF, includes an augmentation stage. During navigation, the robot localizes the centroids of different segments of features in sonar images, which are detected by our improved Otsu TSM, as point landmarks. Using them with the AEKF achieves more accurate and robust estimations of the robot pose and the landmark positions, than with those detected by the maximum entropy TSM. Together with the landmarks identified by the proposed segmentation algorithm, the AEKF-SLAM has achieved reliable detection of cycles in the map and consistent map update on loop

  17. An Improved Otsu Threshold Segmentation Method for Underwater Simultaneous Localization and Mapping-Based Navigation.

    Science.gov (United States)

    Yuan, Xin; Martínez, José-Fernán; Eckert, Martina; López-Santidrián, Lourdes

    2016-07-22

    The main focus of this paper is on extracting features with SOund Navigation And Ranging (SONAR) sensing for further underwater landmark-based Simultaneous Localization and Mapping (SLAM). According to the characteristics of sonar images, in this paper, an improved Otsu threshold segmentation method (TSM) has been developed for feature detection. In combination with a contour detection algorithm, the foreground objects, although presenting different feature shapes, are separated much faster and more precisely than by other segmentation methods. Tests have been made with side-scan sonar (SSS) and forward-looking sonar (FLS) images in comparison with other four TSMs, namely the traditional Otsu method, the local TSM, the iterative TSM and the maximum entropy TSM. For all the sonar images presented in this work, the computational time of the improved Otsu TSM is much lower than that of the maximum entropy TSM, which achieves the highest segmentation precision among the four above mentioned TSMs. As a result of the segmentations, the centroids of the main extracted regions have been computed to represent point landmarks which can be used for navigation, e.g., with the help of an Augmented Extended Kalman Filter (AEKF)-based SLAM algorithm. The AEKF-SLAM approach is a recursive and iterative estimation-update process, which besides a prediction and an update stage (as in classical Extended Kalman Filter (EKF)), includes an augmentation stage. During navigation, the robot localizes the centroids of different segments of features in sonar images, which are detected by our improved Otsu TSM, as point landmarks. Using them with the AEKF achieves more accurate and robust estimations of the robot pose and the landmark positions, than with those detected by the maximum entropy TSM. Together with the landmarks identified by the proposed segmentation algorithm, the AEKF-SLAM has achieved reliable detection of cycles in the map and consistent map update on loop closure, which is

  18. STUDIES ON THE CONTRIBUTION OF THE PUBLIC MATING STALLIONS FROM ARAD STATION ON LOCAL HORSE IMPROVEMENT

    Directory of Open Access Journals (Sweden)

    I. TĂPĂLAGĂ

    2007-10-01

    Full Text Available Public Mating Stations are state’s units which are breeding stallions produced bythe National Stud farms. They are maintained there only for one reason: to be usedfor reproduction and improvement of the local horse populations. Each StallionStation has its own territory on a geographical determined area, in this case Arad,Bihor and Hunedoara counties. In the mating season, almost all of the stallions areallocated (by breeds and demands for a group of communes where mare ownersasked for them.

  19. The Single-Molecule Centroid Localization Algorithm Improves the Accuracy of Fluorescence Binding Assays.

    Science.gov (United States)

    Hua, Boyang; Wang, Yanbo; Park, Seongjin; Han, Kyu Young; Singh, Digvijay; Kim, Jin H; Cheng, Wei; Ha, Taekjip

    2018-03-13

    Here, we demonstrate that the use of the single-molecule centroid localization algorithm can improve the accuracy of fluorescence binding assays. Two major artifacts in this type of assay, i.e., nonspecific binding events and optically overlapping receptors, can be detected and corrected during analysis. The effectiveness of our method was confirmed by measuring two weak biomolecular interactions, the interaction between the B1 domain of streptococcal protein G and immunoglobulin G and the interaction between double-stranded DNA and the Cas9-RNA complex with limited sequence matches. This analysis routine requires little modification to common experimental protocols, making it readily applicable to existing data and future experiments.

  20. Social media in cancer care: opportunities to improve care in locally advanced breast cancer.

    Science.gov (United States)

    Simmons, Christine; Rajmohan, Yanchini; Poonja, Zia; Adilman, Rachel

    2014-03-01

    To examine the current data supporting use of social media in breast cancer clinical care. Although opportunities to utilize social media to increase knowledge have been commonly seized, the opportunity to improve communication among clinicians is lagging. Locally advanced breast cancer (LABC) requires timely coordination of care among many specialists, and presents an excellent scenario for enhanced utilization of current IT strategies. A systematic review was conducted to assess the use of social media to enhance breast cancer care. In addition, a Web-based search using common search engines and publicly available social media was conducted to determine the prevalence of information and networking pages aimed at patients and clinicians. Over 400 articles were retrieved; 81% focused on delivery of information or online support to patients, 17% focused on delivery of information to physicians, and 1% focused on the use of social media to improve collaboration among clinicians. Web searches retrieved millions of hits, with very few hits relating to improving collaboration among clinicians. Although there is significant potential to utilize current technologies to improve care for patients and improve connectedness among clinicians, most of the currently available technologies focus solely on the delivery of information.

  1. Severe fuel damage experiments performed in the QUENCH facility with 21-rod bundles of LWR-type

    International Nuclear Information System (INIS)

    Sepold, L.; Hering, W.; Schanz, G.; Scholtyssek, W.; Steinbrueck, M.; Stuckert, J.

    2006-01-01

    The objective of the QUENCH experimental program at the Karlsruhe Research Center is to investigate core degradation and the hydrogen source term that results from quenching/flooding an uncovered core, to examine the physical/chemical behavior of overheated fuel elements under different flooding conditions, and to create a data base for model development and improvement of severe fuel damage (SFD) code systems. The large-scale 21-rod bundle experiments conducted in the QUENCH out-of-pile facility are supported by an extensive separate-effects test program, by modeling activities as well as application and improvement of SFD code systems. International cooperations exist with institutions mainly within the European Union but e.g. also with the Russian Academy of Science (IBRAE, Moscow) and the CSARP program of the USNRC. So far, eleven experiments have been performed, two of them with B 4 C absorber material. Experimental parameters were: the temperature at initiation of reflood, the degree of peroxidation, the quench medium, i.e. water or steam, and its injection rate, the influence of a B 4 C absorber rod, the effect of steam-starved conditions before quench, the influence of air oxidation before quench, and boil-off behavior of a water-filled bundle with subsequent quenching. The paper gives an overview of the QUENCH program with its organizational structure, describes the test facility and the test matrix with selected experimental results. (author)

  2. Fluorescence quenching of plastic scintillators in oxygen

    Science.gov (United States)

    Horstmann, D.; Holm, U.

    1993-01-01

    The plastic scintillators SCSN-38, SCSN-81T, 3HF in polystyrene and a PMMA based Polivar scintillator show a loss in light yield when operated in air or oxygen. Both the fluorescence of the base material polystyrene or the PMMA admixture naphtalene as well as that of the dyes is reduced. The quenching ratio is proportional to the partial pressure of the surrounding oxygen. The maximum overall quenching amounts to 11.1% for SCSN-38 in one atmosphere of oxygen when excited with light of 262 nm.

  3. Fluorescence quenching of plastic scintillators in oxygen

    International Nuclear Information System (INIS)

    Horstmann, D.; Holm, U.

    1992-01-01

    The plastic scintillators SCSN-38, SCSN-81T, 3HF in polystyrene and a PMMA based Polivar scintillator show a loss in light yield when operated in air or oxygen. Both the fluorescence of the base material polystyrene or the PMMA admixture naphtalene as well as that of the dyes is reduced. The quenching ratio is proportional to the partial pressure of the surrounding oxygen. The maximum overall quenching amounts to 11.1 % for SCSN-38 in one atmosphere of oxygen when excited with light of 262 nm. (Author)

  4. Quenching of Einstein-coefficients by photons

    International Nuclear Information System (INIS)

    Aumayr, F.; Lee, W.; Skinner, C.H.; Suckewer, S.

    1991-03-01

    Experimental evidence is presented for the change of Einstein's A- coefficients for spontaneous transitions from the upper laser level of argon ion laser discharge due to the presence of the high- intensity laser flux. To demonstrate that this quenching effect cannot be attributed to a reduction in self-absorption of the strong spontaneous emission line, absorption and line profile measurements have been performed. Computer modelling of the reduction of self absorption due to Rabi splitting also indicated that this effect is too small to explain the observed quenching of spontaneous line emissions. 13 refs., 11 figs

  5. Quench in high temperature superconductor magnets

    CERN Document Server

    Schwartz, J.

    2013-01-01

    High field superconducting magnets using high temperature superconductors are being developed for high energy physics, nuclear magnetic resonance and energy storage applications. Although the conductor technology has progressed to the point where such large magnets can be readily envisioned, quench protection remains a key challenge. It is well-established that quench propagation in HTS magnets is very slow and this brings new challenges that must be addressed. In this paper, these challenges are discussed and potential solutions, driven by new technologies such as optical fiber based sensors and thermally conducting electrical insulators, are reviewed.

  6. Focused impedance measurement (FIM). A new technique with improved zone localization.

    Science.gov (United States)

    Rabbani, K S; Sarker, M; Akond, M H; Akter, T

    1999-04-20

    Conventional four-electrode impedance measurements (FEIM) cannot localize a zone of interest in a volume conductor. On the other hand, the recently developed electrical impedance tomography (EIT) system offers an image with reasonable resolution, but is complex and needs many electrodes. By placing two FEIM systems perpendicular to each other over a common zone at the center and combining the two results, it is possible to obtain enhanced sensitivity over this central zone. This is the basis of the proposed new method of focused impedance measurement (FIM). Sensitivity maps in both 2D and 3D show the desired improvement. A comparison of stomach-emptying studies also indicates the improvement achieved. This new method may be useful for impedance measurements of large organs like stomach, heart, and lungs. Being much simpler in comparison to EIT, multifrequency systems can be simply built for FIM. Besides, FIM may have utility in other fields like geology where impedance measurements are performed.

  7. Improved radiotherapy for locally advanced Non-Small Cell Lung Carcinoma (NSCLC) patients

    DEFF Research Database (Denmark)

    Ottosson, Wiviann

    be reduced by the DIBH method for the lung cancer patients. The overall aim of the clinical part of this thesis was to clarify the potential benefit of offering DIBH gating, compared to free-breathing (FB), for lung cancer patients. Particularly, the benefits for locally advanced non-small cell lung cancer......Lung cancer is worldwide one of the most common cancer diseases with a high mortality rate. There is thus an urgent need for improving radiotherapy for these patients. Radiotherapy for lung cancer patients is challenging because the tumor and organs at risk (OARs) move with the breathing motion....... Deep-Inspiration-Breath-Hold (DIBH) is a technique that potentially can improve the treatment for these patients. DIBH is frequently and routinely used for breast cancer treatments. However, it is still an experimental method for lung cancer patients e.g. due to preconceptions about their incapability...

  8. Quench detection and behaviour in case of quench in the ITER magnet systems

    International Nuclear Information System (INIS)

    Coatanea-Gouachet, M.

    2012-02-01

    The quench of one of the ITER magnet system is an irreversible transition from superconducting to normal resistive state, of a conductor. This normal zone propagates along the cable in conduit conductor dissipating a large power. The detection has to be fast enough to dump out the magnetic energy and avoid irreversible damage of the systems. The primary quench detection in ITER is based on voltage detection, which is the most rapid detection. The very magnetically disturbed environment during the plasma scenario makes the voltage detection particularly difficult, inducing large inductive components in the coils and voltage compensations have to be designed to discriminate the resistive voltage associated with the quench. A conceptual design of the quench detection based on voltage measurements is proposed for the three majors magnet systems of ITER. For this, a clear methodology was developed. It includes the classical hot spot criterion, the quench propagation study using the commercial code Gandalf and the careful estimation of the inductive disturbances by developing the TrapsAV code. Specific solutions have been proposed for the compensation in the three ITER magnet systems and for the quench detection parameters, which are the voltage threshold (in the range of 0.1 V - 0.55 V) and the holding time (in the range of 1-1.4 s). The selected values, in particular the holding time, are sufficiently high to ensure the reliability of the system and avoid fast safety discharges not induced by a quench, which is a classical problem. (author)

  9. Sustaining a quality improvement culture in local health departments applying for accreditation.

    Science.gov (United States)

    Verma, Pooja; Moran, John W

    2014-01-01

    This article focuses on local health departments (LHDs) that are advanced in accreditation and quality improvement (QI) efforts and the barriers and facilitators associated with sustaining improvements and building an organizational culture of QI. To understand the barriers and facilitators associated with building and sustaining progress toward a QI culture in LHDs. Quantitative data from a self-reporting survey and qualitative data from telephone interviews. Twenty-two LHDs across the United States responded to the survey. Ten of the 22 LHD respondents participated in telephone interviews. QI lead staff at LHDs that are advanced in accreditation preparation and QI. Self-reported LHD survey ratings against indicators for a QI culture, and the identified barriers and facilitators around sustaining QI initiatives. Of the 6 domains of a QI culture measured in the survey, the percentages of respondents that scored themselves highly to at least 1 indicator in each domain are as follows: leadership commitment (100%); employee empowerment (100%); teamwork and collaboration (100%); continuous process improvement (86%); customer focus (72%); and QI infrastructure (64%). Qualitative data from 10 telephone interviews revealed that key barriers to sustaining progress around QI included staff turnover, budget cuts, and major crises or events that arise as priority. Key facilitators included leadership commitment, accreditation, and dedication of resources and staff time to QI. When engaging in QI, LHDs should consider investing efforts in gaining leadership support and dedicating staff time early in the QI journey to ensure that QI efforts and initiatives are sustained. Local health departments interested in developing a QI culture should also consider pursuing accreditation, as it provides a structured framework for continuous improvement. They should also actively develop QI knowledge and skills among all staff members to minimize the negative impact of staff turnover.

  10. Improved localization of cellular membrane receptors using combined fluorescence microscopy and simultaneous topography and recognition imaging

    Energy Technology Data Exchange (ETDEWEB)

    Duman, M; Pfleger, M; Chtcheglova, L A; Neundlinger, I; Bozna, B L; Ebner, A; Schuetz, G J; Hinterdorfer, P [Institute for Biophysics, University of Linz, Altenbergerstrasse 69, A-4040 Linz (Austria); Zhu, R; Mayer, B [Christian Doppler Laboratory for Nanoscopic Methods in Biophysics, Institute for Biophysics, University of Linz, Altenbergerstrasse 69, A-4040 Linz (Austria); Rankl, C; Moertelmaier, M; Kada, G; Kienberger, F [Agilent Technologies Austria GmbH, Aubrunnerweg 11, A-4040 Linz (Austria); Salio, M; Shepherd, D; Polzella, P; Cerundolo, V [Cancer Research UK Tumor Immunology Group, Weatherall Institute of Molecular Medicine, Nuffield Department of Medicine, University of Oxford, Oxford OX3 9DS (United Kingdom); Dieudonne, M, E-mail: ferry_kienberger@agilent.com [Agilent Technologies Belgium, Wingepark 51, Rotselaar, AN B-3110 (Belgium)

    2010-03-19

    The combination of fluorescence microscopy and atomic force microscopy has a great potential in single-molecule-detection applications, overcoming many of the limitations coming from each individual technique. Here we present a new platform of combined fluorescence and simultaneous topography and recognition imaging (TREC) for improved localization of cellular receptors. Green fluorescent protein (GFP) labeled human sodium-glucose cotransporter (hSGLT1) expressed Chinese Hamster Ovary (CHO) cells and endothelial cells (MyEnd) from mouse myocardium stained with phalloidin-rhodamine were used as cell systems to study AFM topography and fluorescence microscopy on the same surface area. Topographical AFM images revealed membrane features such as lamellipodia, cytoskeleton fibers, F-actin filaments and small globular structures with heights ranging from 20 to 30 nm. Combined fluorescence and TREC imaging was applied to detect density, distribution and localization of YFP-labeled CD1d molecules on {alpha}-galactosylceramide ({alpha}GalCer)-loaded THP1 cells. While the expression level, distribution and localization of CD1d molecules on THP1 cells were detected with fluorescence microscopy, the nanoscale distribution of binding sites was investigated with molecular recognition imaging by using a chemically modified AFM tip. Using TREC on the inverted light microscope, the recognition sites of cell receptors were detected in recognition images with domain sizes ranging from {approx} 25 to {approx} 160 nm, with the smaller domains corresponding to a single CD1d molecule.

  11. Radiotherapy is associated with significant improvement in local and regional control in Merkel cell carcinoma

    Directory of Open Access Journals (Sweden)

    Kang Susan H

    2012-10-01

    Full Text Available Abstract Introduction Merkel cell carcinoma (MCC is a rare tumour of skin. This study is a retrospective audit of patients with MCC from St Vincent’s and Mater Hospital, Sydney, Australia. The aim of this study was to investigate the influence of radiotherapy (RT on the local and regional control of MCC lesions and survival of patients with MCC. Method The data bases in anatomical pathology, RT and surgery. We searched for patients having a diagnosis of MCC between 1996 and 2007. Patient, tumour and treatment characteristics were collected and analysed. Univariate survival analysis of categorical variables was conducted with the Kaplan-Meier method together with the Log-Rank test for statistical significance. Continuous variables were assessed using the Cox regression method. Multivariate analysis was performed for significant univariate results. Results Sixty seven patients were found. Sixty two who were stage I-III and were treated with radical intent were analysed. 68% were male. The median age was 74 years. Forty-two cases (68% were stage I or II, and 20 cases (32% were stage III. For the subset of 42 stage I and II patients, those that had RT to their primary site had a 2-year local recurrence free survival of 89% compared with 36% for patients not receiving RT (p Conclusions RT is associated with significant improvement in local and regional control in Merkel cell carcinoma. Immunosuppression is an important factor in overall survival.

  12. Weighted Least Squares Techniques for Improved Received Signal Strength Based Localization

    Directory of Open Access Journals (Sweden)

    José R. Casar

    2011-09-01

    Full Text Available The practical deployment of wireless positioning systems requires minimizing the calibration procedures while improving the location estimation accuracy. Received Signal Strength localization techniques using propagation channel models are the simplest alternative, but they are usually designed under the assumption that the radio propagation model is to be perfectly characterized a priori. In practice, this assumption does not hold and the localization results are affected by the inaccuracies of the theoretical, roughly calibrated or just imperfect channel models used to compute location. In this paper, we propose the use of weighted multilateration techniques to gain robustness with respect to these inaccuracies, reducing the dependency of having an optimal channel model. In particular, we propose two weighted least squares techniques based on the standard hyperbolic and circular positioning algorithms that specifically consider the accuracies of the different measurements to obtain a better estimation of the position. These techniques are compared to the standard hyperbolic and circular positioning techniques through both numerical simulations and an exhaustive set of real experiments on different types of wireless networks (a wireless sensor network, a WiFi network and a Bluetooth network. The algorithms not only produce better localization results with a very limited overhead in terms of computational cost but also achieve a greater robustness to inaccuracies in channel modeling.

  13. Quench detection method for 2G HTS wire

    International Nuclear Information System (INIS)

    Marchevsky, M; Xie, Y-Y; Selvamanickam, V

    2010-01-01

    2G HTS conductors are increasingly used in various commercial applications and their thermal and electrical stability is an important reliability factor. Detection and prevention of quenches in 2G wire-based cables and solenoids has proven to be a difficult engineering task. This is largely due to a very slow normal zone propagation in coated conductors that leads to formation of localized hotspots while the rest of the conductor remains in the superconducting state. We propose an original method of quench and hotspot detection for 2G wires and coils that is based upon local magnetic sensing and takes advantage of 2G wire planar geometry. We demonstrate our technique experimentally and show that its sensitivity is superior to the known voltage detection scheme. A unique feature of the method is its capability to remotely detect instant degradation of the wire critical current even before a normal zone is developed within the conductor. Various modifications of the method applicable to practical device configurations are discussed.

  14. Quench detection method for 2G HTS wire

    Energy Technology Data Exchange (ETDEWEB)

    Marchevsky, M; Xie, Y-Y; Selvamanickam, V, E-mail: maxmarche@gmail.co, E-mail: yxie@superpower-inc.co [SuperPower, Inc., 450 Duane Avenue, Schenectady, NY 12304 (United States)

    2010-03-15

    2G HTS conductors are increasingly used in various commercial applications and their thermal and electrical stability is an important reliability factor. Detection and prevention of quenches in 2G wire-based cables and solenoids has proven to be a difficult engineering task. This is largely due to a very slow normal zone propagation in coated conductors that leads to formation of localized hotspots while the rest of the conductor remains in the superconducting state. We propose an original method of quench and hotspot detection for 2G wires and coils that is based upon local magnetic sensing and takes advantage of 2G wire planar geometry. We demonstrate our technique experimentally and show that its sensitivity is superior to the known voltage detection scheme. A unique feature of the method is its capability to remotely detect instant degradation of the wire critical current even before a normal zone is developed within the conductor. Various modifications of the method applicable to practical device configurations are discussed.

  15. A test for Improvement of high resolution Quantitative Precipitation Estimation for localized heavy precipitation events

    Science.gov (United States)

    Lee, Jung-Hoon; Roh, Joon-Woo; Park, Jeong-Gyun

    2017-04-01

    Accurate estimation of precipitation is one of the most difficult and significant tasks in the area of weather diagnostic and forecasting. In the Korean Peninsula, heavy precipitations are caused by various physical mechanisms, which are affected by shortwave trough, quasi-stationary moisture convergence zone among varying air masses, and a direct/indirect effect of tropical cyclone. In addition to, various geographical and topographical elements make production of temporal and spatial distribution of precipitation is very complicated. Especially, localized heavy rainfall events in South Korea generally arise from mesoscale convective systems embedded in these synoptic scale disturbances. In weather radar data with high temporal and spatial resolution, accurate estimation of rain rate from radar reflectivity data is too difficult. Z-R relationship (Marshal and Palmer 1948) have adapted representatively. In addition to, several methods such as support vector machine (SVM), neural network, Fuzzy logic, Kriging were utilized in order to improve the accuracy of rain rate. These methods show the different quantitative precipitation estimation (QPE) and the performances of accuracy are different for heavy precipitation cases. In this study, in order to improve the accuracy of QPE for localized heavy precipitation, ensemble method for Z-R relationship and various techniques was tested. This QPE ensemble method was developed by a concept based on utilizing each advantage of precipitation calibration methods. The ensemble members were produced for a combination of different Z-R coefficient and calibration method.

  16. The effect of science learning integrated with local potential to improve science process skills

    Science.gov (United States)

    Rahardini, Riris Riezqia Budy; Suryadarma, I. Gusti Putu; Wilujeng, Insih

    2017-08-01

    This research was aimed to know the effectiveness of science learning that integrated with local potential to improve student`s science process skill. The research was quasi experiment using non-equivalent control group design. The research involved all student of Muhammadiyah Imogiri Junior High School on grade VII as a population. The sample in this research was selected through cluster random sampling, namely VII B (experiment group) and VII C (control group). Instrument that used in this research is a nontest instrument (science process skill observation's form) adapted Desak Megawati's research (2016). The aspect of science process skills were making observation and communication. The data were using univariat (ANOVA) analyzed at 0,05 significance level and normalized gain score for science process skill increase's category. The result is science learning that integrated with local potential was effective to improve science process skills of student (Sig. 0,00). This learning can increase science process skill, shown by a normalized gain score value at 0,63 (medium category) in experiment group and 0,29 (low category) in control group.

  17. New Local, National and Regional Cereal Price Indices for Improved Identification of Food Insecurity

    Science.gov (United States)

    Brown, Molly E.; Tondel, Fabien; Thorne, Jennifer A.; Essam, Timothy; Mann, Bristol F.; Stabler, Blake; Eilerts, Gary

    2011-01-01

    Large price increases over a short time period can be indicative of a deteriorating food security situation. Food price indices developed by the United Nations Food and Agriculture Organization (FAO) are used to monitor food price trends at a global level, but largely reflect supply and demand conditions in export markets. However, reporting by the United States Agency for International Development (USAID)'s Famine Early Warning Systems Network (FEWS NET) indicates that staple cereal prices in many markets of the developing world, especially in surplus-producing areas, often have a delayed and variable response to international export market price trends. Here we present new price indices compiled for improved food security monitoring and assessment, and specifically for monitoring conditions of food access across diverse food insecure regions. We found that cereal price indices constructed using market prices within a food insecure region showed significant differences from the international cereals price, and had a variable price dispersion across markets within each marketshed. Using satellite-derived remote sensing information that estimates local production and the FAO Cereals Index as predictors, we were able to forecast movements of the local or national price indices in the remote, arid and semi-arid countries of the 38 countries examined. This work supports the need for improved decision-making about targeted aid and humanitarian relief, by providing earlier early warning of food security crises.

  18. Local administration of prostaglandin E1 combined with silicone chamber improves peripheral nerve regeneration.

    Science.gov (United States)

    Najafpour, Alireza; Mohammadi, Rahim; Faraji, Darab; Amini, Keyvan

    2013-01-01

    The aim of this study was to assess the effect of locally administered prostaglandin E1 on peripheral nerve regeneration and functional recovery. Sixty male healthy white Wistar rats were divided into four experimental groups (n = 15), randomly: In transected group (TC), left sciatic nerve was transected and stumps were fixed in the adjacent muscle. In treatment group defect was bridged using silicone graft (SIL/PE) filled with 10 μL prostaglandin E1. In silicone graft group (SIL), the graft was filled with phosphate-buffered saline alone. In sham-operated group (SHAM), sciatic nerve was exposed and manipulated. Each group was subdivided into three subgroups of five animals each and regenerated nerve fibers were studied 4, 8 and 12 weeks after surgery. Behavioral testing, sciatic nerve functional study, gastrocnemius muscle mass and morphometric indices confirmed faster recovery of regenerated axons in SIL/PE than SIL group (p prostaglandin E1 improved functional recovery and morphometric indices of sciatic nerve. Local application of prostaglandin E1 improved functional recovery and morphometric indices of sciatic nerve. Copyright © 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  19. Mechanisms of Local Planarization Improvement Using Solo Pad in Chemical Mechanical Polishing

    Science.gov (United States)

    Isobe, Akira; Yokoyama, Toshiyuki; Komiyama, Takashi; Kurokawa, Syuhei

    2013-12-01

    The mechanism of local planarization improvement using a solo pad in chemical mechanical polishing (CMP) was investigated, and the pad surface temperature was found to be the key factor. The use of a solo pad results in better planarity than that of a stacked pad under the same process conditions. When Cu CMP evaluation was conducted at various platen temperatures, a good correlation of local planarity to pad surface temperature was confirmed regardless of the pad type. Planarity improved when the pad surface temperature was lowered, and the solo pad had a lower temperature than the stacked pad at the same platen temperature. It is considered that the solo pad has a higher heat conductance than the stacked pad, so that heat generated during polishing is transferred to the platen more easily through the solo pad than through the stacked pad. The reason for the better planarity with the lower pad surface temperature was explained by the change in pad elasticity by the temperature.

  20. Locally administrated perindopril improves healing in an ovariectomized rat tibial osteotomy model.

    Directory of Open Access Journals (Sweden)

    Xiong Zhao

    Full Text Available Angiotensin-converting enzyme inhibitors are widely prescribed to regulate blood pressure. High doses of orally administered perindopril have previously been shown to improve fracture healing in a mouse femur fracture model. In this study, perindopril was administered directly to the fracture area with the goal of stimulating fracture repair. Three months after being ovariectomized (OVX, tibial fractures were produced in Sprague-Dawley rats and subsequently stabilized with intramedullary wires. Perindopril (0.4 mg/kg/day was injected locally at the fractured site for a treatment period of 7 days. Vehicle reagent was used as a control. Callus quality was evaluated at 2 and 4 weeks post-fracture. Compared with the vehicle group, perindopril treatment significantly increased bone formation, increased biomechanical strength, and improved microstructural parameters of the callus. Newly woven bone was arranged more tightly and regularly at 4 weeks post-fracture. The ultimate load increased by 66.1 and 76.9% (p<0.01, and the bone volume over total volume (BV/TV increased by 29.9% and 24.3% (p<0.01 at 2 and 4 weeks post-fracture, respectively. These findings suggest that local treatment with perindopril could promote fracture healing in ovariectomized rats.

  1. Improved Local Ternary Patterns for Automatic Target Recognition in Infrared Imagery

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    Xiaosheng Wu

    2015-03-01

    Full Text Available This paper presents an improved local ternary pattern (LTP for automatic target recognition (ATR in infrared imagery. Firstly, a robust LTP (RLTP scheme is proposed to overcome the limitation of the original LTP for achieving the invariance with respect to the illumination transformation. Then, a soft concave-convex partition (SCCP is introduced to add some flexibility to the original concave-convex partition (CCP scheme. Referring to the orthogonal combination of local binary patterns (OC_LBP, the orthogonal combination of LTP (OC_LTP is adopted to reduce the dimensionality of the LTP histogram. Further, a novel operator, called the soft concave-convex orthogonal combination of robust LTP (SCC_OC_RLTP, is proposed by combing RLTP, SCCP and OC_LTP. Finally, the new operator is used for ATR along with a blocking schedule to improve its discriminability and a feature selection technique to enhance its efficiency. Experimental results on infrared imagery show that the proposed features can achieve competitive ATR results compared with the state-of-the-art methods.

  2. Localized quench in 1+1 conformal field theory

    Directory of Open Access Journals (Sweden)

    Tikhanovskaya Maria

    2016-01-01

    Full Text Available We study the boundary dual of AdS3 spacetime with a point particle. Particles in AdS3 generate topological defects, which allows to formulate the geodesic image method for boundary correlators. We propose the generalization of the geodesic recipe to arbitrary time intervals in case of the bulk spacetime deformed by a point particle.

  3. Improved methods for estimating local terrestrial water dynamics from GRACE in the Northern High Plains

    Science.gov (United States)

    Seyoum, Wondwosen M.; Milewski, Adam M.

    2017-12-01

    Investigating terrestrial water cycle dynamics is vital for understanding the recent climatic variability and human impacts in the hydrologic cycle. In this study, a downscaling approach was developed and tested, to improve the applicability of terrestrial water storage (TWS) anomaly data from the Gravity Recovery and Climate Experiment (GRACE) satellite mission for understanding local terrestrial water cycle dynamics in the Northern High Plains region. A non-parametric, artificial neural network (ANN)-based model, was utilized to downscale GRACE data by integrating it with hydrological variables (e.g. soil moisture) derived from satellite and land surface model data. The downscaling model, constructed through calibration and sensitivity analysis, was used to estimate TWS anomaly for watersheds ranging from 5000 to 20,000 km2 in the study area. The downscaled water storage anomaly data were evaluated using water storage data derived from an (1) integrated hydrologic model, (2) land surface model (e.g. Noah), and (3) storage anomalies calculated from in-situ groundwater level measurements. Results demonstrate the ANN predicts monthly TWS anomaly within the uncertainty (conservative error estimate = 34 mm) for most of the watersheds. Seasonal derived groundwater storage anomaly (GWSA) from the ANN correlated well (r = ∼0.85) with GWSAs calculated from in-situ groundwater level measurements for a watershed size as small as 6000 km2. ANN downscaled TWSA matches closely with Noah-based TWSA compared to standard GRACE extracted TWSA at a local scale. Moreover, the ANN-downscaled change in TWS replicated the water storage variability resulting from the combined effect of climatic and human impacts (e.g. abstraction). The implications of utilizing finer resolution GRACE data for improving local and regional water resources management decisions and applications are clear, particularly in areas lacking in-situ hydrologic monitoring networks.

  4. Application of Best Estimate Approach for Modelling of QUENCH-03 and QUENCH-06 Experiments

    Directory of Open Access Journals (Sweden)

    Tadas Kaliatka

    2016-04-01

    In this article, the QUENCH-03 and QUENCH-06 experiments are modelled using ASTEC and RELAP/SCDAPSIM codes. For the uncertainty and sensitivity analysis, SUSA3.5 and SUNSET tools were used. The article demonstrates that applying the best estimate approach, it is possible to develop basic QUENCH input deck and to develop the two sets of input parameters, covering maximal and minimal ranges of uncertainties. These allow simulating different (but with the same nature tests, receiving calculation results with the evaluated range of uncertainties.

  5. Improving oncoplastic breast tumor bed localization for radiotherapy planning using image registration algorithms

    Science.gov (United States)

    Wodzinski, Marek; Skalski, Andrzej; Ciepiela, Izabela; Kuszewski, Tomasz; Kedzierawski, Piotr; Gajda, Janusz

    2018-02-01

    Knowledge about tumor bed localization and its shape analysis is a crucial factor for preventing irradiation of healthy tissues during supportive radiotherapy and as a result, cancer recurrence. The localization process is especially hard for tumors placed nearby soft tissues, which undergo complex, nonrigid deformations. Among them, breast cancer can be considered as the most representative example. A natural approach to improving tumor bed localization is the use of image registration algorithms. However, this involves two unusual aspects which are not common in typical medical image registration: the real deformation field is discontinuous, and there is no direct correspondence between the cancer and its bed in the source and the target 3D images respectively. The tumor no longer exists during radiotherapy planning. Therefore, a traditional evaluation approach based on known, smooth deformations and target registration error are not directly applicable. In this work, we propose alternative artificial deformations which model the tumor bed creation process. We perform a comprehensive evaluation of the most commonly used deformable registration algorithms: B-Splines free form deformations (B-Splines FFD), different variants of the Demons and TV-L1 optical flow. The evaluation procedure includes quantitative assessment of the dedicated artificial deformations, target registration error calculation, 3D contour propagation and medical experts visual judgment. The results demonstrate that the currently, practically applied image registration (rigid registration and B-Splines FFD) are not able to correctly reconstruct discontinuous deformation fields. We show that the symmetric Demons provide the most accurate soft tissues alignment in terms of the ability to reconstruct the deformation field, target registration error and relative tumor volume change, while B-Splines FFD and TV-L1 optical flow are not an appropriate choice for the breast tumor bed localization problem

  6. Dry Sliding Wear Behavior of EN25 Steel Treated by Different Quenching Media

    Directory of Open Access Journals (Sweden)

    Bassam Ali Ahmed

    2010-10-01

    Full Text Available The present investigation aims to study the effect of heat treatment by quenching in different quenching media (salt water, water and oil following by tempering on wear resistance of EN25 steel. EN25 steel is an alloy of medium carbon low alloy steel which is used for many applications requiring high tensile strength and wear resistance such as connecting rods, adapters and in power sectors extensively. The specimens are machined to 20 mm in length and 10 mm in diameter. This study is done by two stages: The first stage is done by austenitizing EN25 steel to 850 for 1 hr by quenching the specimens in three different quenching media and then tempered at 300 in air. While the second stage is performed by wear test. Dry sliding wear test is done by using pin –on-disc technique by varying the loads as 5, 10, 15, 20 and 25 N, also varying the time as 5, 10, 15, 20, 25 and 30 min respectively. The microstructure examination, hardness and followed roughness tests are also done for the specimens before and after wear test. The results of this work showed that an improving in wear resistance and hardness for the specimen quenched by salt water more than for water and oil. At the same time the roughness decreasing for the specimen quenched by salt water more than for water and oil.

  7. Voltage distribution within superconducting coils during quench

    International Nuclear Information System (INIS)

    Tominaka, T.; Hara, N.; Kuroda, K.

    1988-01-01

    A computer program which can be applied to the calculation of voltage distribution within superconducting coils during quench has been developed. The calculation is compared with an experiment for a small superconducting solenoid, and the propriety of the calculation is discussed

  8. Multiple mechanisms quench passive spiral galaxies

    Science.gov (United States)

    Fraser-McKelvie, Amelia; Brown, Michael J. I.; Pimbblet, Kevin; Dolley, Tim; Bonne, Nicolas J.

    2018-02-01

    We examine the properties of a sample of 35 nearby passive spiral galaxies in order to determine their dominant quenching mechanism(s). All five low-mass (M⋆ environments. We postulate that cluster-scale gas stripping and heating mechanisms operating only in rich clusters are required to quench low-mass passive spirals, and ram-pressure stripping and strangulation are obvious candidates. For higher mass passive spirals, while trends are present, the story is less clear. The passive spiral bar fraction is high: 74 ± 15 per cent, compared with 36 ± 5 per cent for a mass, redshift and T-type matched comparison sample of star-forming spiral galaxies. The high mass passive spirals occur mostly, but not exclusively, in groups, and can be central or satellite galaxies. The passive spiral group fraction of 74 ± 15 per cent is similar to that of the comparison sample of star-forming galaxies at 61 ± 7 per cent. We find evidence for both quenching via internal structure and environment in our passive spiral sample, though some galaxies have evidence of neither. From this, we conclude no one mechanism is responsible for quenching star formation in passive spiral galaxies - rather, a mixture of mechanisms is required to produce the passive spiral distribution we see today.

  9. Simulation of the Quench-06 experiment with Scdapsim; Simulacion del experimento Quench-06 con Scdapsim

    Energy Technology Data Exchange (ETDEWEB)

    Angel M, E. del; Nunez C, A.; Amador G, R. [CNSNS, Dr. Barragan No. 779, 03020 Mexico D.F. (Mexico)]. e-mail: edangelm@cnsns.gob.mx

    2003-07-01

    The present work describes the pattern of the called Quench installation developed and used by the National Commission of Nuclear Security and Safeguards (CNSNS) for their participation in the International Standard Problem 45 (ISP), organized by the Nuclear Energy Agency (NEA). The exercise consisted on the simulation of the denominated experiment Quench-06 carried out in the experimental installation Quench located in the Forschungszentrum laboratory in Karlsruhe, Germany. The experiment Quench-06 consisted on simulating the sudden and late injection of water in a fuel assemble for a pressurized reactor (PWR). The CNSNS uses the version bd of the SCDAPSIM code developed by the company Innovative Software Systems (ISS) to simulate this experiment. The obtained results showed that the code is able to predict the experiment partially when overestimating the hydrogen production and of the partial fused of some fuel pellets, but predicting correctly the damage in the shroud. (Author)

  10. STUDY ON PROJECTS CONTRACTED BY ROP - AXIS 2 PRIORITY - IMPROVING REGIONAL TRANSPORT INFRASTRUCTURE AND LOCAL

    Directory of Open Access Journals (Sweden)

    Ceausescu Aurelian Ionut

    2012-03-01

    Full Text Available This axis priority is to increase the main purpose of accessibility regions, the population mobility, goods and services to stimulate sustainable economic. Investment in transport infrastructure to facilitate mobility of people and goods, reducing the costs of transport of goods and passengers, improving access to the regional markets, increase the efficiency of economic activities, energy saving and time, creating conditions for expanding trade and implicitly productive investment. Developing transport networks will facilitate the cooperation interregional and will contribute significantly to increase competitiveness of enterprises/firms and the labour mobility, and, therefore, a development faster to Romania on the whole, but also of each region. The development of urban transport network will take into account the existing structure of public transportation to ensure where possible, improve the infrastructure of roads, which will contribute to use in a more efficient way of public transportation. Rehabilitation and upgrading urban streets, and construction, rehabilitation and upgrading of roads to his belt (the status of county Road will contribute to urban improve traffic, cut on the time of transport, road and face elimination in their localities crossing safely.

  11. Management of Local Stressors Can Improve the Resilience of Marine Canopy Algae toGlobal Stressors

    NARCIS (Netherlands)

    Strain, E.M.A.; van Belzen, J.; van Dalen, J.; Bouma, T.J.; Airoldi, L.

    2015-01-01

    Coastal systems are increasingly threatened by multiple local anthropogenic and global climatic stressors. With the difficulties in remediating global stressors, management requires alternative approaches that focus on local scales. We used manipulative experiments to test whether reducing local

  12. Classical vs. evolved quenching parameters and procedures in scintillation measurements: The importance of ionization quenching

    International Nuclear Information System (INIS)

    Bagan, H.; Tarancon, A.; Rauret, G.; Garcia, J.F.

    2008-01-01

    The quenching parameters used to model detection efficiency variations in scintillation measurements have not evolved since the decade of 1970s. Meanwhile, computer capabilities have increased enormously and ionization quenching has appeared in practical measurements using plastic scintillation. This study compares the results obtained in activity quantification by plastic scintillation of 14 C samples that contain colour and ionization quenchers, using classical (SIS, SCR-limited, SCR-non-limited, SIS(ext), SQP(E)) and evolved (MWA-SCR and WDW) parameters and following three calibration approaches: single step, which does not take into account the quenching mechanism; two steps, which takes into account the quenching phenomena; and multivariate calibration. Two-step calibration (ionization followed by colour) yielded the lowest relative errors, which means that each quenching phenomenon must be specifically modelled. In addition, the sample activity was quantified more accurately when the evolved parameters were used. Multivariate calibration-PLS also yielded better results than those obtained using classical parameters, which confirms that the quenching phenomena must be taken into account. The detection limits for each calibration method and each parameter were close to those obtained theoretically using the Currie approach

  13. Classical vs. evolved quenching parameters and procedures in scintillation measurements: The importance of ionization quenching

    Science.gov (United States)

    Bagán, H.; Tarancón, A.; Rauret, G.; García, J. F.

    2008-07-01

    The quenching parameters used to model detection efficiency variations in scintillation measurements have not evolved since the decade of 1970s. Meanwhile, computer capabilities have increased enormously and ionization quenching has appeared in practical measurements using plastic scintillation. This study compares the results obtained in activity quantification by plastic scintillation of 14C samples that contain colour and ionization quenchers, using classical (SIS, SCR-limited, SCR-non-limited, SIS(ext), SQP(E)) and evolved (MWA-SCR and WDW) parameters and following three calibration approaches: single step, which does not take into account the quenching mechanism; two steps, which takes into account the quenching phenomena; and multivariate calibration. Two-step calibration (ionization followed by colour) yielded the lowest relative errors, which means that each quenching phenomenon must be specifically modelled. In addition, the sample activity was quantified more accurately when the evolved parameters were used. Multivariate calibration-PLS also yielded better results than those obtained using classical parameters, which confirms that the quenching phenomena must be taken into account. The detection limits for each calibration method and each parameter were close to those obtained theoretically using the Currie approach.

  14. Using radial basis functions in airborne gravimetry for local geoid improvement

    Science.gov (United States)

    Li, Xiaopeng

    2017-10-01

    Radial basis functions (RBFs) have been used extensively in satellite geodetic applications. However, to the author's knowledge, their role in processing and modeling airborne gravity data has not yet been fully advocated or extensively investigated in detail. Compared with satellite missions, the airborne data are more suitable for these kinds of localized basis functions especially considering the following facts: (1) Unlike the satellite missions that can provide global or near global data coverage, airborne gravity data are usually geographically limited. (2) It is also band limited in the frequency domain. (3) It is straightforward to formulate the RBF observation equations from an airborne gravimetric system. In this study, a set of band-limited RBF is developed to model and downward continue the airborne gravity data for local geoid improvement. First, EIGEN6c4 coefficients are used to simulate a harmonic field to test the performances of RBF on various sampling, noise, and flight height levels, in order to gain certain guidelines for processing the real data. Here, the RBF method not only successfully recovers the harmonic field but also presents filtering properties due to its particular design in the frequency domain. Next, the software was tested for the GSVS14 (Geoid Slope Validation Survey 2014) area in Iowa as well as for the area around Puerto Rico and the US Virgin Islands by use of the real airborne gravity data from the Gravity for the Redefinition of the American Vertical Datum (GRAV-D) project. By fully utilizing the three-dimensional correlation information among the flight tracks, the RBF can also be used as a data cleaning tool for airborne gravity data adjustment and cleaning. This property is further extended to surface gravity data cleaning, where conventional approaches have various limitations. All the related numerical results clearly show the importance and contribution of the use of the RBF for high- resolution local gravity field

  15. Improved local mean decomposition for modulation information mining and its application to machinery fault diagnosis

    Science.gov (United States)

    Liu, Zhiliang; Zuo, Ming J.; Jin, Yaqiang; Pan, Deng; Qin, Yong

    2017-06-01

    Local mean decomposition (LMD) has been developed for modulation information mining. Its performance is dependent on boundary condition, envelope estimation, and stopping criterion. This paper proposes a soft sifting stopping criterion that enables LMD to achieve a self-adaptive stop for each sifting process. In the proposed method, we define an objective function that considers two characteristics, namely, the root mean square and the excess kurtosis, of the target signal. To optimize this objective function, a heuristic mechanism is proposed to automatically determine the optimal number of sifting iterations. Experimental results on simulated signals demonstrate the effectiveness of the proposed soft sifting stopping criterion for improving the accuracy of LMD, and finally the proposed method is applied to modulation information mining for gear fault diagnosis.

  16. An Improved Hybrid Genetic Algorithm with a New Local Search Procedure

    Directory of Open Access Journals (Sweden)

    Wen Wan

    2013-01-01

    Full Text Available One important challenge of a hybrid genetic algorithm (HGA (also called memetic algorithm is the tradeoff between global and local searching (LS as it is the case that the cost of an LS can be rather high. This paper proposes a novel, simplified, and efficient HGA with a new individual learning procedure that performs a LS only when the best offspring (solution in the offspring population is also the best in the current parent population. Additionally, a new LS method is developed based on a three-directional search (TD, which is derivative-free and self-adaptive. The new HGA with two different LS methods (the TD and Neld-Mead simplex is compared with a traditional HGA. Four benchmark functions are employed to illustrate the improvement of the proposed method with the new learning procedure. The results show that the new HGA greatly reduces the number of function evaluations and converges much faster to the global optimum than a traditional HGA. The TD local search method is a good choice in helping to locate a global “mountain” (or “valley” but may not perform the Nelder-Mead method in the final fine tuning toward the optimal solution.

  17. Crossbreeding locally adapted hair sheep to improve productivity and meat quality

    Directory of Open Access Journals (Sweden)

    Juliano Issakowicz

    Full Text Available ABSTRACT: The use of lambs from crossing of local with specialized sheep breeds for meat production may lead to higher meat deposition and a smaller fat amount in the carcass, with a more adequate nutritional profile for human consumption. This study investigated the performance, carcass and meat characteristics of lambs from the Morada Nova and Santa Inês locally adapted hair breeds and crosses between Dorper × Morada Nova and Dorper × Santa Inês slaughtered at approximately 35 kg. Morada Nova lambs showed lower (p < 0.05 performance compared to the other genetic groups resulting in a higher age at slaughter (p < 0.05. Crossbred Dorper × Santa Inês and Dorper × Morada Nova lambs showed better characteristics for meat production with better (p < 0.05 conformation as well as leg and carcass compacteness index. Dorper × Santa Inês have a fatty acid profile that is more suitable for human consumption than Dorper × Morada Nova lambs do (p < 0.05; however, both had lower (p < 0.05 intramuscular lipid content (as measured by ether extract levels from Longíssimus lumborum compared with purebred lambs. Therefore, when the objective is to obtain lean meat, with improved nutritional profile to reduce risks of cardiovascular disease, the use of breeds and crosses that reduce animal slaughter age, such as the ½ Dorper × ½ Santa Inês crossbred, is an interesting alternative.

  18. Vicus: Exploiting local structures to improve network-based analysis of biological data.

    Directory of Open Access Journals (Sweden)

    Bo Wang

    2017-10-01

    Full Text Available Biological networks entail important topological features and patterns critical to understanding interactions within complicated biological systems. Despite a great progress in understanding their structure, much more can be done to improve our inference and network analysis. Spectral methods play a key role in many network-based applications. Fundamental to spectral methods is the Laplacian, a matrix that captures the global structure of the network. Unfortunately, the Laplacian does not take into account intricacies of the network's local structure and is sensitive to noise in the network. These two properties are fundamental to biological networks and cannot be ignored. We propose an alternative matrix Vicus. The Vicus matrix captures the local neighborhood structure of the network and thus is more effective at modeling biological interactions. We demonstrate the advantages of Vicus in the context of spectral methods by extensive empirical benchmarking on tasks such as single cell dimensionality reduction, protein module discovery and ranking genes for cancer subtyping. Our experiments show that using Vicus, spectral methods result in more accurate and robust performance in all of these tasks.

  19. Vicus: Exploiting local structures to improve network-based analysis of biological data.

    Science.gov (United States)

    Wang, Bo; Huang, Lin; Zhu, Yuke; Kundaje, Anshul; Batzoglou, Serafim; Goldenberg, Anna

    2017-10-01

    Biological networks entail important topological features and patterns critical to understanding interactions within complicated biological systems. Despite a great progress in understanding their structure, much more can be done to improve our inference and network analysis. Spectral methods play a key role in many network-based applications. Fundamental to spectral methods is the Laplacian, a matrix that captures the global structure of the network. Unfortunately, the Laplacian does not take into account intricacies of the network's local structure and is sensitive to noise in the network. These two properties are fundamental to biological networks and cannot be ignored. We propose an alternative matrix Vicus. The Vicus matrix captures the local neighborhood structure of the network and thus is more effective at modeling biological interactions. We demonstrate the advantages of Vicus in the context of spectral methods by extensive empirical benchmarking on tasks such as single cell dimensionality reduction, protein module discovery and ranking genes for cancer subtyping. Our experiments show that using Vicus, spectral methods result in more accurate and robust performance in all of these tasks.

  20. Locally applied simvastatin improves fracture healing at late period in osteoporotic rat

    Science.gov (United States)

    Tian, Faming; Zhang, Liu; Kang, Yuchuan; Zhang, Junshan; Ao, Jiao; Yang, Fang

    effect of simvastatin locally applied from a bioactive polymer coating of implants on osteoporotic fracture healing at late period. Methods:Femur fracture model was established on normal or osteotoporotic mature female SD rats, intramedullary stabilization was achieved with uncoated titanium Kirschnerwires in normal rats(group A),with polymer-only coated vs. polymer plus simvastatin coated titanium Kirschner wires in osteoporotic rats(group B and C, respectively).Femurs were harvested after 12 weeks, and underwent radiographic and histologic analysis, as well as immunohistochemical evaluation for BMP-2 expression. Results:Radiographic results demonstrated progressed callus in the simvastatin-treated groups compared to the uncoated group.The histologic analysis revealed a significantly processed callus with irregular-shaped newly formed bone trabeculae in simvastatin-treated group. Immunohistochemical evaluation showed markedly higher expression levels of B:MP-2 in simvastatin-treated group.Conclusions: The present study revealed a improved fracture healing under local application of simvastatin in osteoporotic rat,which might partially from upregulation of the B:MP-2 expression at fractured site.

  1. Using Participatory Approach to Improve Availability of Spatial Data for Local Government

    Science.gov (United States)

    Kliment, T.; Cetl, V.; Tomič, H.; Lisiak, J.; Kliment, M.

    2016-09-01

    Nowadays, the availability of authoritative geospatial features of various data themes is becoming wider on global, regional and national levels. The reason is existence of legislative frameworks for public sector information and related spatial data infrastructure implementations, emergence of support for initiatives as open data, big data ensuring that online geospatial information are made available to digital single market, entrepreneurs and public bodies on both national and local level. However, the availability of authoritative reference spatial data linking the geographic representation of the properties and their owners are still missing in an appropriate quantity and quality level, even though this data represent fundamental input for local governments regarding the register of buildings used for property tax calculations, identification of illegal buildings, etc. We propose a methodology to improve this situation by applying the principles of participatory GIS and VGI used to collect observations, update authoritative datasets and verify the newly developed datasets of areas of buildings used to calculate property tax rates issued to their owners. The case study was performed within the district of the City of Požega in eastern Croatia in the summer 2015 and resulted in a total number of 16072 updated and newly identified objects made available online for quality verification by citizens using open source geospatial technologies.

  2. Local mandate improves equity of paid sick leave coverage: Seattle’s experience

    Directory of Open Access Journals (Sweden)

    Jennifer L. Romich

    2017-01-01

    Full Text Available Abstract Background Paid sick leave allows workers to take time off work for personal or family health needs, improving health and potentially limiting infectious diseases. The U.S. has no national sick leave mandate, and many American workers - particularly those at lower income levels - have no right to paid time off for their own or family members’ health needs. This article reports on outcomes of a local mandate, the City of Seattle Paid Sick and Safe Time Ordinance, which requires certain employers to provide paid sick leave to eligible workers. Methods Survey collectors contacted a stratified random sample of Seattle employers before the Ordinance went into effect and one year later. Pre- and post- analysis draws on responses to survey items by 345 employers who were subject to the paid sick leave mandate. Results Awareness of the policy and provision of paid leave grew significantly over the year after the Ordinance was enacted. More employers offered leave to full-time workers (80.8 to 93.9%, p < .001 and part-time workers (47.1 to 66.7%, p < .001 with particularly large increases in the hospitality sector, which includes food workers (coverage of any hospitality employee: 27.5 to 85.0%, p < .001. Conclusions Absent a federal policy, local paid sick time mandates can increase paid sick leave coverage, an important social determinant of health.

  3. Intravenous avidin chase improved localization of radiolabeled streptavidin in intraperitoneal xenograft pretargeted with biotinylated antibody

    International Nuclear Information System (INIS)

    Zhang Meili; Sakahara, Harumi; Yao Zhengsheng; Saga, Tsuneo; Nakamoto, Yuhi; Sato, Noriko; Nakada, Hiroshi; Yamashina, Ikuo; Konishi, Junji

    1997-01-01

    In the present study, we examined the effect of avidin administered intravenously (i.v.) on the biodistribution of radiolabeled streptavidin in mice bearing intraperitoneal (IP) xenografts pretargeted with biotinylated antibody. Tumors were established in nude mice by IP inoculation of LS180 human colon cancer cells. Monoclonal antibody MLS128, which recognizes Tn antigen on mucin, was biotinylated and injected IP into the IP tumor-bearing mice. Radioiodinated streptavidin was administered IP or i.v. 48 h after pretargeting of biotinylated antibody. Avidin was administered i.v. 30 min prior to streptavidin injection. The localization of radioiodinated streptavidin in the tumor pretargeted with biotinylated antibody was significantly higher than that without pretargeting and that of radioiodinated MLS128 by the one-step method. Avidin administration significantly accelerated the clearance of radioiodinated streptavidin in blood and other normal tissues and increased the tumor-to-blood radioactivity ratio regardless of administration route of streptavidin. The i.v. avidin chase improved tumor localization of radiolabeled streptavidin in the IP xenografts pretargeted with biotinylated antibody

  4. Improved spatial localization in magnetic resonance spectroscopic imaging with two-dimensional PSF-Choice encoding.

    Science.gov (United States)

    Zhang, Shelley HuaLei; Maier, Stephan E; Panych, Lawrence P

    2018-03-03

    Magnetic resonance spectroscopic imaging (MRSI), under low-spatial resolution settings, often suffers signal contamination from neighboring voxels due to ringing artifacts. Spatial localization can be improved by constraining the point-spread-function (PSF). Here the effectiveness of the two-dimensional PSF-Choice technique in providing improved spatial localization for MRSI is demonstrated. The PSF-Choice technique constrains the PSF to a desired shape by manipulating the weighting of RF excitation pulse throughout phase-encode steps. Based on a Point REsolved SpectroScopy (PRESS)-type sequence, PSF-Choice encoding was implemented along two dimensions to excite a two-dimensional Gaussian profile, by replacing the usual RF excitation pulse with a train of pulses that is modified at each phase-encoding step. The method was proven mathematically, and demonstrated experimentally in phantoms containing prostate relevant metabolic compounds of choline, creatine and citrate. Using a dedicated prostate-mimicking spectroscopy phantom surrounded by oil, it was found that there is significantly less signal contamination from oil for PSF-Choice encoding compared with standard phase encoding. In particular, with standard phase encoding, there was a significant difference (p = 0.014) between ratios of Choline + Creatine to Citrate for voxels well within the phantom compared to voxels within the phantom but near the boundary with oil. The ratios in boundary voxels were also significantly different (p = 0.035) from reference values obtained using the prostate phantom with no oil present. In contrast, no significant differences were found in comparisons of these ratios when encoding with PSF-Choice. The PSF-Choice scheme applied along two dimensions produces MR spectroscopic images with substantially reduced truncation artifacts and spectral contamination. Copyright © 2018 Elsevier Inc. All rights reserved.

  5. Adoption of JMM practices - A key to performance improvement of a local automotive industry

    Science.gov (United States)

    Mohiuddin, A. K. M.; Haji, A. Jabbar Julia Bt.; Khan, Ahsan Ali; Mustafizul Karim, A. N.

    2017-03-01

    It is imperative for a manufacturing company all over the world to constantly look for ways to increase productivity and at the same time to lower cost to secure a competitive position. It is recognized that practices associated with Japanese Manufacturing Management (JMM) can yield a superior competitive advantage in terms of productivity, quality and provide overall successful business performance. This paper discusses the transfer of the best practices of the JMM locally and analyses the impact of adoption and adaptation of the management system as an in-depth case study conducted in a Malaysian automotive company. This study is to identify what are the changes in terms of the philosophy and practices undertaken by the company and ascertain the impact of the JMM on its manufacturing and financial performances. The elements of business performance from the viewpoint of manufacturing are based on safety, Parts Per Million (PPM), in-line Defect per Unit (DPU), First Time Quality (FTQ), cycle time, productivity, efficiency and stock level. The results show a positive impact to the automotive plant manufacturing performance. For example, safety index has reduced to 0 major accident occurrences. The PPM and In-line DPU have improved by 98% and 91% respectively whereas the FTQ has improved by 167%. Cycle time has reduced from 20 to 6 minutes and productivity increased up to 43% whilst the efficiency reached at 99.9%. The stock level was reduced from half month to 3 days after the adoption of the JMM. The revenue has increased up to 92%, the percentage of expenses has reduced from 11.04% to 3.06% giving an improvement of 72% whilst the net profit has increased from 5.33% to 8.15%. The Return of Asset (RoA) and Return of Equity (RoE) also showed slight improvement despite the effects from the restructuring exercise, Tsunami calamity and fluctuation in Japanese exchange rate.

  6. Radiation induced boiling enhancement. 5th report, Leidenfrost temperature and quenching condition

    Energy Technology Data Exchange (ETDEWEB)

    Imai, Yasuyuki; Okamoto, Koji [Tokyo Univ., Tokai, Ibaraki (Japan); Fukamachi, Norihiro; Takamasa, Tomoji [Tokyo Univ. of Mercantile Marine, Tokyo (Japan); Mishima, Kaichiro [Kyoto Univ., Kumatori, Osaka (Japan); Furuya, Masahiro [Central Research Inst. of Electric Power Industry, Tokyo (Japan)

    2002-07-01

    Improvement of quenching requires that the cooling liquid can contact the heating surface, or a high-wettability heating surface, even if a vapor film is generated on the surface. From this point of view, an experimental study to investigate Leidenfrost condition and quenching was performed by use of an oxide semiconductor-coated material under a {gamma} ray irradiation environment. The results showed that Leidenfrost condition of oxidized titanium was improved up to 30-50degC after 800kGy {sup 60}Co {gamma} ray irradiated. Liquid film velocity flowing down a heated vertical wall was estimated using the result of the experiment. (author)

  7. Electrode quenching control for highly efficient CsPbBr3 perovskite light-emitting diodes via surface plasmon resonance and enhanced hole injection by Au nanoparticles

    Science.gov (United States)

    Meng, Yan; Wu, Xiaoyan; Xiong, Ziyang; Lin, Chunyan; Xiong, Zuhong; Blount, Ethan; Chen, Ping

    2018-04-01

    Compared to organic-inorganic hybrid metal halide perovskites, all-inorganic cesium lead halides (e.g, CsPbBr3) hold greater promise in being emissive materials for light-emitting diodes owing to their superior optoelectronic properties as well as their higher stabilities. However, there is still considerable potential for breakthroughs in the current efficiency of CsPbBr3 perovskite light-emitting diodes (PeLEDs). Electrode quenching is one of the main problems limiting the current efficiency of PeLEDs when poly(3,4-ethylenedioxythiophene): poly(styrenesulfonate) (PEDOT:PSS) is used as the hole injection layer. In this work, electrode quenching control was realized via incorporating Au NPs into PEDOT:PSS. As a result, the CsPbBr3 PeLEDs realized an improvement in maximum luminescence ranging from ˜2348 to ˜7660 cd m-2 (˜226% enhancement) and current efficiency from 1.65 to 3.08 cd A-1 (˜86% enhancement). Such substantial enhancement of the electroluminescent performance can be attributed to effective electrode quenching control at the PEDOT:PSS/CsPbBr3 perovskite interface via the combined effects of local surface plasma resonance coupling and enhanced hole transportation in the PEDOT:PSS layer by Au nanoparticles.

  8. 40 CFR 86.327-79 - Quench checks; NOX analyzer.

    Science.gov (United States)

    2010-07-01

    ... any flow rate into the reaction chamber. This includes, but is not limited to, sample capillary, ozone... Quench checks; NOX analyzer. (a) Perform the reaction chamber quench check for each model of high vacuum reaction chamber analyzer prior to initial use. (b) Perform the reaction chamber quench check for each new...

  9. Intercritical Heat Treatment Effects on Low Carbon Steels Quenched ...

    African Journals Online (AJOL)

    Six low carbon steels containing carbon in the range 0.13-0.18wt%C were studied after intercritical quenching, intercritical quenching with low temperature tempering, intercritical annealing and intercritical normalizing using specimens originally quenched from intermediate austenitizing temperature (9500C). The studies ...

  10. Effects of Various Quenching Media on Mechanical Properties of ...

    African Journals Online (AJOL)

    The machined specimen of the steel was heated at 8800Cthen quenched in water, engine oil, palm kernel oil, cotton seed oil and olive oil. Tensile strength, hardness and impact energy were used to measure the quenching effectiveness of the various media. The microstructures and mechanical properties of the quenched ...

  11. Modeling of Interfilament Coupling Currents and Their Effect on Magnet Quench Protection

    CERN Document Server

    Ravaioli, E; Chlachidze, G; Maciejewski, M; Sabbi, G; Stoynev, S E; Verweij, A

    2016-01-01

    Variations in the transport current of a superconducting magnet cause several types of transitory losses. Due to its relatively short time constant, usually of the order of a few tens of milliseconds, interfilament coupling loss can have a significant effect on the coil protection against overheating after a quench. This loss is deposited in the strands and can facilitate a more homogeneous transition to the normal state of the coil turns. Furthermore, the presence of local interfilament coupling currents reduces the magnet's differential inductance, which in turn provokes a faster discharge of the transport current. The lumped-element dynamic electrothermal model of a superconducting magnet has been developed to reproduce these effects. Simulations are compared to experimental electrical transients and found in good agreement. After its validation, the model can be used for predicting the performance of quench protection systems based on energy extraction, quench heaters, the newly developed coupling-loss-in...

  12. Martensitic transformation induced by quenching or by plastic deformation

    Science.gov (United States)

    Félix-Henry, I.; Dagbert, C.; Hyspecka, L.; Galland, J.

    2003-10-01

    Nowadays the possibility to use the TRIP effect (Transformation Induced Plasticity) is stated not only for the high alloy steels but also for the low alloy steels. This effect is connected with the martensitic transformation, but not necessarily the strain induced martensitic transformation induced by deformation provokes the TRIP effect: decisive factors are the chemical composition, the stability of the austenite, its grain size, the particles geometry and their distribution, and also the temperature, amplitude and rate of deformation during the mechanical loading. The change of energy is compared between the creation of the quench and strain induced martensite with and without the TRIP effect. The molar enthalpy released during the creation of quench induced martensite in the continually cooled austenite of the alloy Fe-23.87wt %Ni-0.39wt %C, was calculated from DSC (differential scanning calorimeter) measurements. For this same material, the consumed work during tensile tests was determined at different temperatures. The temperatures interval was between Ms and Md. At each température, a volume traction of strain induced martensite was created and thé TRIP effect could occur, that is both extraordinary great elongation at high ultimate tensile strength and nearly no local deformation (no creation of a neck). This paper conclues with a discussion on the preferences and lacks in the use of TRIP effect in low alloy steels.

  13. Postoperative radiotherapy improves local control and survival in patients with uterine leiomyosarcoma

    International Nuclear Information System (INIS)

    Wong, Philip; Han, Kathy; Sykes, Jenna; Catton, Charles; Laframboise, Stephane; Fyles, Anthony; Manchul, Lee; Levin, Wilfred; Milosevic, Michael

    2013-01-01

    To examine the role of radiotherapy (RT) in uterine leiomyosarcomas (LMS) and to determine the patient population who may benefit from RT. From 1998–2008, 69 patients with primary uterine LMS underwent hysterectomy with or without pelvic radiotherapy to a median dose of 45 Gy. Univariate analysis was performed using the Kaplan-Meier method and cumulative-incidence function, and multivariate analyses using Fine and Gray or Cox proportional hazard models. Following surgery, 32 out of 69 patients received RT. There was no evidence of any correlation between patient, disease and treatment characteristics and the use of RT. Median follow-up was 57 months. RT was associated with reduced local recurrence (3y LR 19% vs. 39%; Gray’s p = 0.019) and improved overall survival (3y OS 69% vs. 35%; log-rank p = 0.025) on univariate analysis. Multivariate analysis demonstrated that RT reduced LR (HR: 0.28, CI: 0.11-0.69, p = 0.006) and increased OS (HR: 0.44, CI: 0.23-0.85, p = 0.014) independent of other clinical and pathologic factors. Positive surgical margins increased the odds of LR (HR: 5.6, CI: 2.3-13.4, p = 0.00012). Large tumor size and advanced stage (II-IV) were associated with the development of distant metastases and inferior OS. Postoperative pelvic RT reduces LR and improves OS of patients with uterine LMS

  14. Improving local clustering based top-L link prediction methods via asymmetric link clustering information

    Science.gov (United States)

    Wu, Zhihao; Lin, Youfang; Zhao, Yiji; Yan, Hongyan

    2018-02-01

    Networks can represent a wide range of complex systems, such as social, biological and technological systems. Link prediction is one of the most important problems in network analysis, and has attracted much research interest recently. Many link prediction methods have been proposed to solve this problem with various techniques. We can note that clustering information plays an important role in solving the link prediction problem. In previous literatures, we find node clustering coefficient appears frequently in many link prediction methods. However, node clustering coefficient is limited to describe the role of a common-neighbor in different local networks, because it cannot distinguish different clustering abilities of a node to different node pairs. In this paper, we shift our focus from nodes to links, and propose the concept of asymmetric link clustering (ALC) coefficient. Further, we improve three node clustering based link prediction methods via the concept of ALC. The experimental results demonstrate that ALC-based methods outperform node clustering based methods, especially achieving remarkable improvements on food web, hamster friendship and Internet networks. Besides, comparing with other methods, the performance of ALC-based methods are very stable in both globalized and personalized top-L link prediction tasks.

  15. Improved tumor localization with (strept)avidin and labeled biotin as a substitute for antibody

    International Nuclear Information System (INIS)

    Hnatowich, D.J.; Fritz, B.; Virzi, F.; Mardirossian, G.; Rusckowski, M.

    1993-01-01

    We have investigated tumor localization with labeled biotin administered subsequent to unlabeled and unconjugated streptavidin. Nude mice bearing anti-CEA tumors (LS174T) received 10 μg of 111 In-labeled anti-CEA antibody (C110) or 111 In-labeled streptavidin with sacrifice 5 h later. In an examination of pretargeting, other animals received 50 μg of unlabeled streptavidin followed 3 h later with 1 μg of 111 In-labeled biotin (EB 1 ) and sacrifice 2 h later. The biodistribution of labeled streptavidin was similar to that of labeled specific antibody except for lower blood and higher kidney levels. Tumor levels were also lower with labeled streptavidin but, because of still lower levels in liver and blood, the tumor/normal tissue ratios were improved. When unlabeled streptavidin was administered and followed by labeled biotin (pretargeting), tumor levels were further reduced modestly; however, normal tissue levels were greatly reduced such that the tumor/blood and tumor/liver ratios were 10.6 and 2.2 vs 1.5 and 0.5 for the specific antibody. Improvements were seen in all tissues sampled with the exception of kidney and muscle. A further control of labeled biotin alone (without the preinjection of streptavidin) showed minimal accumulations in all tissues with the exception of kidneys. In conclusion, the accumulation of (strept)avidin by passive diffusion in tumor may be comparable, at early times, to the accumulation of specific antibody. (author)

  16. DEVELOPING SCIENCE LEARNING INSTRUMENTS BASED ON LOCAL WISDOM TO IMPROVE STUDENT’S CRITICAL THINKING SKILLS

    Directory of Open Access Journals (Sweden)

    S. Wahyuni

    2015-07-01

    Full Text Available This research aims to develop learning instruments of science i.e. textbook, student worksheet, syllabus, and lesson plan based on local wisdom that can improve critical thinking skills of junior high school students. Indicators of student's critical thinking skills include interpretation, analysis, evaluation and inference. This study is a Research and Development by using analysis, desaign, development, implementation and evaluation (ADDIE method. Expert validation was conducted with the expert test related to the format, content/material, and language. The instruments ware used on the collection data are documentations, validation sheets, observation sheets, and tests. The result of the instrument in the 7th grade of junior high school at Bustanul Ulum Panti Jember showed that there are the improvement of critical thinking skills of student based on the data from test and observation. According to indicator of critical thinking skills, the n-gain value is around 0.47, means moderate interpretation. The conclusions of this research are the learning instruments of science based on local wisdom which develope in the valid category is quite effective to improve students' critical thinking skills.Penelitian ini bertujuan mengembangkan perangkat pembelajaran IPA yang berupa Buku ajar, LKS, Silabus, dan RPP berbasis kearifan lokal untuk meningkatkan kemampuan berpikir kritis siswa SMP. Indikator kemampuan berpikir kritis siswa mencakup interprestasi, analisis, evaluasi dan inferensi. Penelitian ini merupakan penelitian Research and Development dengan metode Analysis, Desaign, Development, Implimentation and Evaluastion (ADDIE. Validasi ahli dilakukan dengan uji expert terkait dengan format, isi/materi, dan bahasa. Instrumen yang digunakan dalam pengambilan data adalah dokumentasi, lembar validasi, lembar observasi, dan tes. Hasil ujicoba instrumen di kelas VII SMP Bustanul ulum Panti Kabupaten Jember menunjukkan adanya peningkatan kemampuan berpikir

  17. Quench from Mott Insulator to Superfluid

    Energy Technology Data Exchange (ETDEWEB)

    Zurek, Wojciech H. [Los Alamos National Laboratory; Dziarmaga, Jacek [Instytut Fizyki Uniwersytetu Jagiello´nskiego; Tylutki, Marek [Instytut Fizyki Uniwersytetu Jagiello´nskiego

    2012-06-01

    We study a linear ramp of the nearest-neighbor tunneling rate in the Bose-Hubbard model driving the system from the Mott insulator state into the superfluid phase. We employ the truncated Wigner approximation to simulate linear quenches of a uniform system in 1...3 dimensions, and in a harmonic trap in 3 dimensions. In all these setups the excitation energy decays like one over third root of the quench time. The -1/3 scaling is explained by an impulse-adiabatic approximation - a variant of the Kibble-Zurek mechanism - describing a crossover from non-adiabatic to adiabatic evolution when the system begins to keep pace with the increasing tunneling rate.

  18. Chiral analysis of quenched baryon masses

    International Nuclear Information System (INIS)

    Young, R.D.; Leinweber, D.B.; Thomas, A.W.; Wright, S. V.

    2002-01-01

    We extend to quenched QCD an earlier investigation of the chiral structure of the masses of the nucleon and the delta in lattice simulations of full QCD. Even after including the meson-loop self-energies which give rise to the leading and next-to-leading nonanalytic behavior (and hence the most rapid variation in the region of light quark mass), we find surprisingly little curvature in the quenched case. Replacing these meson-loop self-energies by the corresponding terms in full QCD yields a remarkable level of agreement with the results of the full QCD simulations. This comparison leads to a very good understanding of the origins of the mass splitting between these baryons

  19. Quantum quench dynamics of the Luttinger model

    Science.gov (United States)

    Iucci, A.; Cazalilla, M. A.

    2009-12-01

    The dynamics of the Luttinger model after a quantum quench is studied. We compute in detail one- and two-point correlation functions for two types of quenches: from a noninteracting to an interacting Luttinger model and vice versa. In the former case, the noninteracting Fermi gas features in the momentum distribution and other correlation functions are destroyed as time evolves. In the infinite-time limit, equal-time correlations are power laws but the critical exponents are found to differ from their equilibrium values. In all cases, we find that these correlations are well described by a generalized Gibbs ensemble [M. Rigol, V. Dunjko, V. Yurovsky, and M. Olshanii, Phys. Rev. Lett. 98, 050405 (2007)], which assigns a momentum-dependent temperature to each eigenmode.

  20. Generic HRTFs May be Good Enough in Virtual Reality. Improving Source Localization through Cross-Modal Plasticity.

    Science.gov (United States)

    Berger, Christopher C; Gonzalez-Franco, Mar; Tajadura-Jiménez, Ana; Florencio, Dinei; Zhang, Zhengyou

    2018-01-01

    Auditory spatial localization in humans is performed using a combination of interaural time differences, interaural level differences, as well as spectral cues provided by the geometry of the ear. To render spatialized sounds within a virtual reality (VR) headset, either individualized or generic Head Related Transfer Functions (HRTFs) are usually employed. The former require arduous calibrations, but enable accurate auditory source localization, which may lead to a heightened sense of presence within VR. The latter obviate the need for individualized calibrations, but result in less accurate auditory source localization. Previous research on auditory source localization in the real world suggests that our representation of acoustic space is highly plastic. In light of these findings, we investigated whether auditory source localization could be improved for users of generic HRTFs via cross-modal learning. The results show that pairing a dynamic auditory stimulus, with a spatio-temporally aligned visual counterpart, enabled users of generic HRTFs to improve subsequent auditory source localization. Exposure to the auditory stimulus alone or to asynchronous audiovisual stimuli did not improve auditory source localization. These findings have important implications for human perception as well as the development of VR systems as they indicate that generic HRTFs may be enough to enable good auditory source localization in VR.

  1. Generic HRTFs May be Good Enough in Virtual Reality. Improving Source Localization through Cross-Modal Plasticity

    Directory of Open Access Journals (Sweden)

    Christopher C. Berger

    2018-02-01

    Full Text Available Auditory spatial localization in humans is performed using a combination of interaural time differences, interaural level differences, as well as spectral cues provided by the geometry of the ear. To render spatialized sounds within a virtual reality (VR headset, either individualized or generic Head Related Transfer Functions (HRTFs are usually employed. The former require arduous calibrations, but enable accurate auditory source localization, which may lead to a heightened sense of presence within VR. The latter obviate the need for individualized calibrations, but result in less accurate auditory source localization. Previous research on auditory source localization in the real world suggests that our representation of acoustic space is highly plastic. In light of these findings, we investigated whether auditory source localization could be improved for users of generic HRTFs via cross-modal learning. The results show that pairing a dynamic auditory stimulus, with a spatio-temporally aligned visual counterpart, enabled users of generic HRTFs to improve subsequent auditory source localization. Exposure to the auditory stimulus alone or to asynchronous audiovisual stimuli did not improve auditory source localization. These findings have important implications for human perception as well as the development of VR systems as they indicate that generic HRTFs may be enough to enable good auditory source localization in VR.

  2. Debris Thermal Hydraulics Modeling of QUENCH Experiments

    International Nuclear Information System (INIS)

    Kisselev, Arcadi E.; Kobelev, Gennadii V.; Strizhov, Valerii F.; Vasiliev, Alexander D.

    2006-01-01

    Porous debris formation and behavior in QUENCH experiments (QUENCH-02, QUENCH-03) plays a considerable role and its adequate modeling is important for thermal analysis. This work is aimed to the development of a numerical module which is able to model thermal hydraulics and heat transfer phenomena occurring during the high-temperature stage of severe accident with the formation of debris region and molten pool. The original approach for debris evolution is developed from classical principles using a set of parameters including debris porosity; average particle diameter; temperatures and mass fractions of solid, liquid and gas phases; specific interface areas between different phases; effective thermal conductivity of each phase, including radiative heat conductivity; mass and energy fluxes through the interfaces. The debris model is based on the system of continuity, momentum and energy conservation equations, which consider the dynamics of volume-averaged velocities and temperatures of fluid, solid and gaseous phases of porous debris. The different mechanisms of debris formation are considered, including degradation of fuel rods according to temperature criteria, taking into consideration some correlations between rod layers thicknesses; degradation of rod layer structure due to thermal expansion of melted materials inside intact rod cladding; debris formation due to sharp temperature drop of previously melted material due to reflood; and transition to debris of material from elements lying above. The porous debris model was implemented to best estimate numerical code RATEG/SVECHA/HEFEST developed for modeling thermal hydraulics and severe accident phenomena in a reactor. The model is used for calculation of QUENCH experiments. The results obtained by the model are compared to experimental data concerning different aspects of thermal behavior: thermal hydraulics of porous debris, radiative heat transfer in a porous medium, the generalized melting and refreezing

  3. Quantum quenches in a holographic Kondo model

    Energy Technology Data Exchange (ETDEWEB)

    Erdmenger, Johanna [Max-Planck-Institut für Physik (Werner-Heisenberg-Institut),Föhringer Ring 6, 80805, Munich (Germany); Institut für Theoretische Physik und Astrophysik, Julius-Maximilians-Universität Würzburg,Am Hubland, 97074 Würzburg (Germany); Flory, Mario [Max-Planck-Institut für Physik (Werner-Heisenberg-Institut),Föhringer Ring 6, 80805, Munich (Germany); Institute of Physics, Jagiellonian University,Łojasiewicza 11, 30-348 Kraków (Poland); Newrzella, Max-Niklas; Strydom, Migael [Max-Planck-Institut für Physik (Werner-Heisenberg-Institut),Föhringer Ring 6, 80805, Munich (Germany); Wu, Jackson M. S. [Department of Physics and Astronomy, University of Alabama,Tuscaloosa, AL 35487 (United States)

    2017-04-10

    We study non-equilibrium dynamics and quantum quenches in a recent gauge/ gravity duality model for a strongly coupled system interacting with a magnetic impurity with SU(N) spin. At large N, it is convenient to write the impurity spin as a bilinear in Abrikosov fermions. The model describes an RG flow triggered by the marginally relevant Kondo operator. There is a phase transition at a critical temperature, below which an operator condenses which involves both an electron and an Abrikosov fermion field. This corresponds to a holographic superconductor in AdS{sub 2} and models the impurity screening. We quench the Kondo coupling either by a Gaussian pulse or by a hyperbolic tangent, the latter taking the system from the condensed to the uncondensed phase or vice-versa. We study the time dependence of the condensate induced by this quench. The timescale for equilibration is generically given by the leading quasinormal mode of the dual gravity model. This mode also governs the formation of the screening cloud, which is obtained as the decrease of impurity degrees of freedom with time. In the condensed phase, the leading quasinormal mode is imaginary and the relaxation of the condensate is over-damped. For quenches whose final state is close to the critical point of the large N phase transition, we study the critical slowing down and obtain the combination of critical exponents zν=1. When the final state is exactly at the phase transition, we find that the exponential ringing of the quasinormal modes is replaced by a power-law behaviour of the form ∼t{sup −a}sin (blog t). This indicates the emergence of a discrete scale invariance.

  4. Quantum quenches in a holographic Kondo model

    International Nuclear Information System (INIS)

    Erdmenger, Johanna; Flory, Mario; Newrzella, Max-Niklas; Strydom, Migael; Wu, Jackson M. S.

    2017-01-01

    We study non-equilibrium dynamics and quantum quenches in a recent gauge/ gravity duality model for a strongly coupled system interacting with a magnetic impurity with SU(N) spin. At large N, it is convenient to write the impurity spin as a bilinear in Abrikosov fermions. The model describes an RG flow triggered by the marginally relevant Kondo operator. There is a phase transition at a critical temperature, below which an operator condenses which involves both an electron and an Abrikosov fermion field. This corresponds to a holographic superconductor in AdS 2 and models the impurity screening. We quench the Kondo coupling either by a Gaussian pulse or by a hyperbolic tangent, the latter taking the system from the condensed to the uncondensed phase or vice-versa. We study the time dependence of the condensate induced by this quench. The timescale for equilibration is generically given by the leading quasinormal mode of the dual gravity model. This mode also governs the formation of the screening cloud, which is obtained as the decrease of impurity degrees of freedom with time. In the condensed phase, the leading quasinormal mode is imaginary and the relaxation of the condensate is over-damped. For quenches whose final state is close to the critical point of the large N phase transition, we study the critical slowing down and obtain the combination of critical exponents zν=1. When the final state is exactly at the phase transition, we find that the exponential ringing of the quasinormal modes is replaced by a power-law behaviour of the form ∼t −a sin (blog t). This indicates the emergence of a discrete scale invariance.

  5. The QUENCH programme at Forschungszentrum Karlsruhe (FZK)

    International Nuclear Information System (INIS)

    Steinbrueck, M.; Schanz, G.; Sepold, L.; Stuckert, J.; Hering, W.; Homann, C.; Miassoedov, A.

    2004-01-01

    The QUENCH programme at FZK was launched to investigate the hydrogen source term during reflood of an overheated reactor core. It consists of large scale bundle experiments, separate-effects tests, modelling activities and application and validation of severe fuel damage (SFD) code systems. The paper describes the experimental part of the programme, namely the experimental facilities and test rigs as well as selected results obtained during the recent years. (author)

  6. Event-by-event jet quenching

    Energy Technology Data Exchange (ETDEWEB)

    Fries, R.J.; Rodriguez, R.; Ramirez, E.

    2010-08-14

    High momentum jets and hadrons can be used as probes for the quark gluon plasma (QGP) formed in nuclear collisions at high energies. We investigate the influence of fluctuations in the fireball on jet quenching observables by comparing propagation of light quarks and gluons through averaged, smooth QGP fireballs with event-by-event jet quenching using realistic inhomogeneous fireballs. We find that the transverse momentum and impact parameter dependence of the nuclear modification factor R{sub AA} can be fit well in an event-by-event quenching scenario within experimental errors. However the transport coefficient {cflx q} extracted from fits to the measured nuclear modification factor R{sub AA} in averaged fireballs underestimates the value from event-by-event calculations by up to 50%. On the other hand, after adjusting {cflx q} to fit R{sub AA} in the event-by-event analysis we find residual deviations in the azimuthal asymmetry v{sub 2} and in two-particle correlations, that provide a possible faint signature for a spatial tomography of the fireball. We discuss a correlation function that is a measure for spatial inhomogeneities in a collision and can be constrained from data.

  7. Event-by-event jet quenching

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, R. [Cyclotron Institute and Physics Department, Texas A and M University, College Station, TX 77843 (United States); Fries, R.J., E-mail: rjfries@comp.tamu.ed [Cyclotron Institute and Physics Department, Texas A and M University, College Station, TX 77843 (United States); RIKEN/BNL Research Center, Brookhaven National Laboratory, Upton, NY 11973 (United States); Ramirez, E. [Physics Department, University of Texas El Paso, El Paso, TX 79968 (United States)

    2010-09-27

    High momentum jets and hadrons can be used as probes for the quark gluon plasma (QGP) formed in nuclear collisions at high energies. We investigate the influence of fluctuations in the fireball on jet quenching observables by comparing propagation of light quarks and gluons through averaged, smooth QGP fireballs with event-by-event jet quenching using realistic inhomogeneous fireballs. We find that the transverse momentum and impact parameter dependence of the nuclear modification factor R{sub AA} can be fit well in an event-by-event quenching scenario within experimental errors. However the transport coefficient q extracted from fits to the measured nuclear modification factor R{sub AA} in averaged fireballs underestimates the value from event-by-event calculations by up to 50%. On the other hand, after adjusting q to fit R{sub AA} in the event-by-event analysis we find residual deviations in the azimuthal asymmetry v{sub 2} and in two-particle correlations, that provide a possible faint signature for a spatial tomography of the fireball. We discuss a correlation function that is a measure for spatial inhomogeneities in a collision and can be constrained from data.

  8. Successful magnet quench test for CAST.

    CERN Multimedia

    Brice Maximilien

    2002-01-01

    The CERN Axion Solar Telescope (CAST) consists of a prototype LHC dipole magnet with photon detectors at each end. It searches for very weakly interacting neutral particles called axions, which should originate in the core of the Sun. The telescope, located at Point 8, can move vertically within its wheeled platform, which travels horizontally along tracks in the floor. In this way, the telescope can view the Sun at sunrise through one end and at sunset through the other end. It has been cooled down to below 1.8 K and reached ~95% of its final magnetic field of 9 tesla before a quench was induced to test the whole cryogenic system under such conditions. The cryogenic system responded as expected to the magnet quench and CAST is now ready to start its three-year search for solar axions. Photos 01 & 02 : Members of the LHC cryogenics team pose in front of the axion telescope on the day of the first quench test, together with some of the CAST collaboration.

  9. Modification of defects and potential fluctuations in slow-cooled and quenched Cu2ZnSnSe4 single crystals

    Science.gov (United States)

    Bishop, Douglas M.; McCandless, Brian; Gershon, Talia; Lloyd, Michael A.; Haight, Richard; Birkmire, Robert

    2017-02-01

    Recent literature reports have shown the ability to manipulate Cu-Zn cation ordering for Cu2ZnSnSe4 (CZTSe) via low temperature treatments. Theoretical arguments suggest that one of the major roadblocks to higher VOC—significant band tailing—could be improved with increased cation order; however, few direct measurements have been reported and significant device improvements have not yet been realized. This report investigates electrical properties, defects, and devices from quenched and slow-cooled single crystals of CZTSe. The extent of disorder was characterized by Raman spectroscopy as well as x-ray diffraction, where the change in Cu-Zn order can be detected by a changing c/a ratio. Quenched samples show higher acceptor concentrations, lower hole mobilities, and a lower-energy photoluminescence (PL) peak than crystals cooled at slower rates, consistent with a reduction in the bandgap. In addition, samples quenched at the highest temperatures showed lower PL yield consistent with higher quantities of deep defects. Devices fabricated using slow-cooled CZTSe single crystals showed improved efficiencies, most notably with increased VOC; however, low temperature intensity-dependent photoluminescence measurements continue to indicate the existence of potential fluctuations. We discuss the possibility that potential fluctuations in slow-cooled samples may be related to the inability to achieve a long range order of the Cu-Zn sub-lattice resulting in local regions of high and low levels of cation order, and consequent local variations in the bandgap. The presence of significant potential fluctuations, even after the slow-cooling step, suggests the difficulty in eliminating band-tailing in this system, and thus, additional approaches may be needed for significant reduction of the VOC deficit.

  10. Improving local health through community health workers in Cambodia: challenges and solutions.

    Science.gov (United States)

    Ozano, Kim; Simkhada, Padam; Thann, Khem; Khatri, Rose

    2018-01-06

    Volunteer community health workers (CHWs) are an important link between the public health system and the community. The 'Community Participation Policy for Health' in Cambodia identifies CHWs as key to local health promotion and as a critical link between district health centres and the community. However, research on the challenges CHWs face and identifying what is required to optimise their performance is limited in the Cambodian context. This research explores the views of CHWs in rural Cambodia, on the challenges they face when implementing health initiatives. Qualitative methodology was used to capture the experiences of CHWs in Kratie and Mondulkiri provinces. Two participatory focus groups with CHWs in Mondulkiri and ten semi-structured interviews in Kratie were conducted. Results from both studies were used to identify common themes. Participants were CHWs, male and female, from rural Khmer and Muslim communities and linked with seven different district health centres. Findings identify that CHWs regularly deliver health promotion to communities. However, systemic, personal and community engagement challenges hinder their ability to function effectively. These include minimal leadership and support from local government, irregular training which focuses on verticalised health programmes, inadequate resources, a lack of professional identity and challenges to achieving behaviour change of community members. In addition, the CHW programme is delivered in a fragmented way that is largely influenced by external aid objectives. When consulted, however, CHWs demonstrate their ability to develop realistic practical solutions to challenges and barriers. The fragmented delivery of the CHW programme in Cambodia means that government ownership is minimal. This, coupled with the lack of defined core training programme or adequate resources, prevents CHWs from reaching their potential. CHWs have positive and realistic ideas on how to improve their role and, subsequently

  11. Water-sanitation-hygiene mapping: an improved approach for data collection at local level.

    Science.gov (United States)

    Giné-Garriga, Ricard; de Palencia, Alejandro Jiménez-Fernández; Pérez-Foguet, Agustí

    2013-10-01

    Strategic planning and appropriate development and management of water and sanitation services are strongly supported by accurate and accessible data. If adequately exploited, these data might assist water managers with performance monitoring, benchmarking comparisons, policy progress evaluation, resources allocation, and decision making. A variety of tools and techniques are in place to collect such information. However, some methodological weaknesses arise when developing an instrument for routine data collection, particularly at local level: i) comparability problems due to heterogeneity of indicators, ii) poor reliability of collected data, iii) inadequate combination of different information sources, and iv) statistical validity of produced estimates when disaggregated into small geographic subareas. This study proposes an improved approach for water, sanitation and hygiene (WASH) data collection at decentralised level in low income settings, as an attempt to overcome previous shortcomings. The ultimate aim is to provide local policymakers with strong evidences to inform their planning decisions. The survey design takes the Water Point Mapping (WPM) as a starting point to record all available water sources at a particular location. This information is then linked to data produced by a household survey. Different survey instruments are implemented to collect reliable data by employing a variety of techniques, such as structured questionnaires, direct observation and water quality testing. The collected data is finally validated through simple statistical analysis, which in turn produces valuable outputs that might feed into the decision-making process. In order to demonstrate the applicability of the method, outcomes produced from three different case studies (Homa Bay District-Kenya-; Kibondo District-Tanzania-; and Municipality of Manhiça-Mozambique-) are presented. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Influence of temperature to quenching on liquid scintillation measurement

    CERN Document Server

    Kato, T

    2003-01-01

    The amount of quench is measured with liquid scintillation spectrometer changing the temperature of the sample. The range of the changed temperature is between 0 deg C and 35 deg C. The measurement is carried out for three kinds of unquenched standard, two quenched standards and fifteen kinds of scintillation cocktail and the mixed sample. It is confirmed that the amount of quench increases for all samples as the temperature rises. The influence of the changed amount of quench to the quench correction is examined. (author)

  13. A new optimization procedure for the accurate characterization of thermal phase transformation curves based on controlled quenching experiments

    Directory of Open Access Journals (Sweden)

    Peterli Maurice

    2016-01-01

    Full Text Available Precise hardness and phase content prediction for quenched steel with the finite element method requires optimal material data, which is usually obtained from measured continuous cooling transformation (CCT diagrams. However, most software packages that are able to predict final phase composition require time temperature transformation (TTT diagrams. TTT diagrams can be calculated from the chemical composition of the material. With this methods the numerical prediction often result in deviations to reality. A newly developed optimization method can improve the accuracy of phase content and hardness prediction after quenching by optimizing the TTT diagram with measured data of controlled quenching experiments.

  14. Improved localization of a 'hot spot' in the lungs for an array of four HPGe detectors

    International Nuclear Information System (INIS)

    Pelled, O.; Tzroya, S.; German, U.; Abraham, A.; Alfassi, Z.B.

    2005-01-01

    Full text: The basic assumption made when calibrating a lung counter is that the deposition of the radioactive aerosols in lungs is homogenous, and therefore the calibration is made with realistic phantoms containing lung sets with homogeneous contamination. Unfortunately, the deposition of the radioactive aerosols is rarely homogenous, and in some cases the contamination can even be present in the form of single 'hot' particles. The deviations from homogeneity in this case can cause an error in activity determination over one order of magnitude. A lung counter system based on four HPGe detectors is operated at Nuclear Research Center Negev - NRCN. The ratios of the counts of the four detectors may be used to obtain information on the point source position, for a more accurate evaluation of the source activity. Some criteria for location determination of a point source in the lungs were investigated in the past, and it was shown that the average error in the activity determination, when using the most promising criteria, for a natural uranium point source, was about 10 %, when the analysis was based on either the 186 keV or the 92 keV energy peaks. A parameter was used to define the successful identification of the point source location in the lungs: the 'hit percentage', which is the percentage of the right locations of the source point from all trials. The highest 'hits percentage' obtained, when analysis of the 186 keV and the 92 keV peaks was performed separately, was about 83 %. In the present work, an improvement of the localization accuracy is presented by simultaneous analysis of several gamma energy peaks. It is shown that the localization process is more accurate and the 'hits percentage' is higher in this case. For the combined analysis of the 186 keV and the 92 keV peaks, a 'hits percentage' of about 94 % was obtained. The average error in the activity determination when using this procedure, is improved to about 2.5 %, much lower than 10 % obtained

  15. Entanglement and thermodynamics after a quantum quench in integrable systems

    Science.gov (United States)

    Alba, Vincenzo; Calabrese, Pasquale

    2017-07-01

    Entanglement and entropy are key concepts standing at the foundations of quantum and statistical mechanics. Recently, the study of quantum quenches revealed that these concepts are intricately intertwined. Although the unitary time evolution ensuing from a pure state maintains the system at zero entropy, local properties at long times are captured by a statistical ensemble with nonzero thermodynamic entropy, which is the entanglement accumulated during the dynamics. Therefore, understanding the entanglement evolution unveils how thermodynamics emerges in isolated systems. Alas, an exact computation of the entanglement dynamics was available so far only for noninteracting systems, whereas it was deemed unfeasible for interacting ones. Here, we show that the standard quasiparticle picture of the entanglement evolution, complemented with integrability-based knowledge of the steady state and its excitations, leads to a complete understanding of the entanglement dynamics in the space-time scaling limit. We thoroughly check our result for the paradigmatic Heisenberg chain.

  16. Oslo model, hyperuniformity, and the quenched Edwards-Wilkinson model

    Science.gov (United States)

    Grassberger, Peter; Dhar, Deepak; Mohanty, P. K.

    2016-10-01

    We present simulations of the one-dimensional Oslo rice pile model in which the critical height at each site is randomly reset after each toppling. We use the fact that the stationary state of this sand-pile model is hyperuniform to reach system of sizes >107 . Most previous simulations were seriously flawed by important finite-size corrections. We find that all critical exponents have values consistent with simple rationals: ν =4/3 for the correlation length exponent, D =9/4 for the fractal dimension of avalanche clusters, and z =10/7 for the dynamical exponent. In addition, we relate the hyperuniformity exponent to the correlation length exponent ν . Finally, we discuss the relationship with the quenched Edwards-Wilkinson model, where we find in particular that the local roughness exponent is αloc=1 .

  17. BAUM: Improving genome assembly by adaptive unique mapping and local overlap-layout-consensus approach.

    Science.gov (United States)

    Wang, Anqi; Wang, Zhanyu; Li, Zheng; Li, Lei M

    2018-01-15

    It is highly desirable to assemble genomes of high continuity and consistency at low cost. The current bottleneck of draft genome continuity using the Second Generation Sequencing (SGS) reads is primarily caused by uncertainty among repetitive sequences. Even though the Single-Molecule Real-Time sequencing technology is very promising to overcome the uncertainty issue, its relatively high cost and error rate add burden on budget or computation. Many long-read assemblers take the overlap-layout-consensus (OLC) paradigm, which is less sensitive to sequencing errors, heterozygosity and variability of coverage. However, current assemblers of SGS data do not sufficiently take advantage of the OLC approach. Aiming at minimizing uncertainty, the proposed method BAUM, breaks the whole genome into regions by adaptive unique mapping; then the local OLC is used to assemble each region in parallel. BAUM can: (1) perform reference-assisted assembly based on the genome of a close species; (2) or improve the results of existing assemblies that are obtained based on short or long sequencing reads. The tests on two eukaryote genomes, a wild rice Oryza longistaminata and a parrot Melopsittacus undulatus, show that BAUM achieved substantial improvement on genome size and continuity. Besides, BAUM reconstructed a considerable amount of repetitive regions that failed to be assembled by existing short read assemblers. We also propose statistical approaches to control the uncertainty in different steps of BAUM. http://www.zhanyuwang.xin/wordpress/index.php/2017/07/21/baum. lilei@amss.ac.cn. Supplementary data are available at Bioinformatics online. © The Author (2018). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  18. Quality improvement in local health departments: results of the NACCHO 2008 survey.

    Science.gov (United States)

    Beitsch, Leslie M; Leep, Carolyn; Shah, Gulzar; Brooks, Robert G; Pestronk, Robert M

    2010-01-01

    To assess the current status of quality improvement (QI) within local health departments (LHDs) and examine the characteristics associated with such QI efforts. A QI module was administered to a representative sample of 545 LHDs along with the core instrument in the 2008 NACCHO Profile survey of all LHDs nationally. Using the Profile survey data set, a quantitative approach was employed to determine the current status of QI within LHDs. Statistical analysis was performed to identify characteristics of LHDs associated with QI. The response rate to the QI module was 82 percent. Of the 448 LHDs that responded to the QI Module, 55 percent reported conducting formal QI efforts during the previous 2 years. Forty-four percent of these LHDs used a specific framework for QI, 56 percent used at least one of four commonly employed QI tools or techniques, and customer focus and satisfaction was the most frequently reported area (76%) of QI efforts. LHDs with large size of jurisdiction population and those with centralized governance were more likely to have engaged in quality or performance improvement, have managers who received formal QI training, and have provided QI training to staff. The 2008 NACCHO Profile QI module furnishes an excellent baseline for measuring progress of health department QI activities as accreditation and other related activities intensify. A clear definition of QI in public health that is understood by practitioners will greatly increase our ability to measure the adoption of QI by LHDs. Further research is necessary to identify and explore some of the predictors and possible barriers to increasing the application of QI by LHDs.

  19. An Improved Compressive Sensing and Received Signal Strength-Based Target Localization Algorithm with Unknown Target Population for Wireless Local Area Networks

    Directory of Open Access Journals (Sweden)

    Jun Yan

    2017-05-01

    Full Text Available In this paper a two-phase compressive sensing (CS and received signal strength (RSS-based target localization approach is proposed to improve position accuracy by dealing with the unknown target population and the effect of grid dimensions on position error. In the coarse localization phase, by formulating target localization as a sparse signal recovery problem, grids with recovery vector components greater than a threshold are chosen as the candidate target grids. In the fine localization phase, by partitioning each candidate grid, the target position in a grid is iteratively refined by using the minimum residual error rule and the least-squares technique. When all the candidate target grids are iteratively partitioned and the measurement matrix is updated, the recovery vector is re-estimated. Threshold-based detection is employed again to determine the target grids and hence the target population. As a consequence, both the target population and the position estimation accuracy can be significantly improved. Simulation results demonstrate that the proposed approach achieves the best accuracy among all the algorithms compared.

  20. Improvement of Lidocaine Local Anesthetic Action Using Lallemantia royleana Seed Mucilage as an Excipient.

    Science.gov (United States)

    Atabaki, Rabi; Hassanpour-Ezatti, Majid

    2014-01-01

    Lallemantia royleana (Balangu) is a well known Iranian medicinal plant that its seed mucilage has many applications in modern pharmacology. Plant mucilage traditionally was used as a gel supplement, and natural matrix for sustained release of drugs. But it seems that these compounds are not a simple additive and also have many undiscovered pharmacological properties. In this research, the anesthetic action of gel prepared from Balangu mucilage alone and its mixture with lidocaine hydrochloride are compared with the effect of commercial 2% lidocaine gel by rat tail flick test. Mucilage of Balangu seed alone showed analgesic effect. Duration and potency of anesthesia induced by gel containing mucilage alone (0.01 g/mL) were identical to commercial 2% lidocaine gel. But, local anesthetic potency and duration of gel made from 2% lidocaine-mucilage gel mixture was significantly higher than commercial 2% lidocaine gel. The gel prepared from mucilage causes a good analgesia with unknown mechanism. Besides, mixture of Balangu mucilage prepared gel with lidocaine improves lidocaine anesthesia. The increase in potency of lidocaine action results from mucilage dermal penetration enhancing effects; and longer anesthetic duration of this mixture are related to the capability of mucilage based gel for sustained drug release.

  1. RENT+: an improved method for inferring local genealogical trees from haplotypes with recombination.

    Science.gov (United States)

    Mirzaei, Sajad; Wu, Yufeng

    2017-04-01

    : Haplotypes from one or multiple related populations share a common genealogical history. If this shared genealogy can be inferred from haplotypes, it can be very useful for many population genetics problems. However, with the presence of recombination, the genealogical history of haplotypes is complex and cannot be represented by a single genealogical tree. Therefore, inference of genealogical history with recombination is much more challenging than the case of no recombination. : In this paper, we present a new approach called RENT+  for the inference of local genealogical trees from haplotypes with the presence of recombination. RENT+  builds on a previous genealogy inference approach called RENT , which infers a set of related genealogical trees at different genomic positions. RENT+  represents a significant improvement over RENT in the sense that it is more effective in extracting information contained in the haplotype data about the underlying genealogy than RENT . The key components of RENT+  are several greatly enhanced genealogy inference rules. Through simulation, we show that RENT+  is more efficient and accurate than several existing genealogy inference methods. As an application, we apply RENT+  in the inference of population demographic history from haplotypes, which outperforms several existing methods. : RENT+  is implemented in Java, and is freely available for download from: https://github.com/SajadMirzaei/RentPlus . : sajad@engr.uconn.edu or ywu@engr.uconn.edu. : Supplementary data are available at Bioinformatics online.

  2. Assessing quality improvement in local health departments: results from the Multi-State Learning Collaborative.

    Science.gov (United States)

    Joly, Brenda M; Booth, Maureen; Shaler, George; Mittal, Prashant

    2012-01-01

    This study examined changes in quality improvement: (1) over a 3-year period, (2) among mini-collaborative participants, and (3) among agencies that were classified in the lowest QI performance quartile. : A QI Maturity Tool was administered to all local health departments in the Multi-State Learning Collaborative states. Factorial ANOVA was performed to determine differences in composite factor scores and interaction effects were explored. : The results revealed a significant increase in the percent of agencies that reported ever implementing a formal QI process from 2009 to 2011 and agencies that participated in a mini-collaborative were more likely than their non-mini-collaborative counterparts to report QI implementation. The findings also suggested significant changes in QI capacity and competency as well as alignment and spread over the course of the grant, among mini-collaborative participants, and among agencies that were originally identified in the lowest QI maturity quartile. No significant changes in organizational culture were revealed by year or among mini-collaborative participants. However, agencies in the lowest quartile saw significant changes in organizational culture during the project period. Significant changes in specific QI domains are possible to detect during a 3-year period. Our research gives us confidence that the QI Maturity Tool measures the right domains and is an important contribution to quantifying the adoption and spread of QI in public health. However, further refinement is needed to better standardize language and definitions of the component parts of a QI system.

  3. Posture estimation for improved photogrammetric localization of pedestrians in monocular infrared imagery

    Science.gov (United States)

    Kundegorski, Mikolaj E.; Breckon, Toby P.

    2015-10-01

    Target tracking complexity within conventional video imagery can be fundamentally attributed to the ambiguity associated with actual 3D scene position of a given tracked object in relation to its observed position in 2D image space. Recent work, within thermal-band infrared imagery, has tackled this challenge head on by returning to classical photogrammetry as a means of recovering the true 3D position of pedestrian targets. A key limitation in such approaches is the assumption of posture - that the observed pedestrian is at full height stance within the scene. Whilst prior work has shown the effects of statistical height variation to be negligible, variations in the posture of the target may still pose a significant source of potential error. Here we present a method that addresses this issue via the use of Support Vector Machine (SVM) regression based pedestrian posture estimation operating on Histogram of Orientated Gradient (HOG) feature descriptors. Within an existing tracking framework, we demonstrate improved target localization that is independent of variations in target posture (i.e. behaviour) and within the statistical error bounds of prior work for pedestrian height posture varying from 0.4-2.4m over a distance to target range of 7-30m.

  4. Fisheye-Based Method for GPS Localization Improvement in Unknown Semi-Obstructed Areas

    Directory of Open Access Journals (Sweden)

    Julien Moreau

    2017-01-01

    Full Text Available A precise GNSS (Global Navigation Satellite System localization is vital for autonomous road vehicles, especially in cluttered or urban environments where satellites are occluded, preventing accurate positioning. We propose to fuse GPS (Global Positioning System data with fisheye stereovision to face this problem independently to additional data, possibly outdated, unavailable, and needing correlation with reality. Our stereoscope is sky-facing with 360° × 180° fisheye cameras to observe surrounding obstacles. We propose a 3D modelling and plane extraction through following steps: stereoscope self-calibration for decalibration robustness, stereo matching considering neighbours epipolar curves to compute 3D, and robust plane fitting based on generated cartography and Hough transform. We use these 3D data with GPS raw data to estimate NLOS (Non Line Of Sight reflected signals pseudorange delay. We exploit extracted planes to build a visibility mask for NLOS detection. A simplified 3D canyon model allows to compute reflections pseudorange delays. In the end, GPS positioning is computed considering corrected pseudoranges. With experimentations on real fixed scenes, we show generated 3D models reaching metric accuracy and improvement of horizontal GPS positioning accuracy by more than 50%. The proposed procedure is effective, and the proposed NLOS detection outperforms CN0-based methods (Carrier-to-receiver Noise density.

  5. Application of a Model for Quenching and Partitioning in Hot Stamping of High-Strength Steel

    Science.gov (United States)

    Zhu, Bin; Liu, Zhuang; Wang, Yanan; Rolfe, Bernard; Wang, Liang; Zhang, Yisheng

    2018-04-01

    Application of quenching and partitioning process in hot stamping has proven to be an effective method to improve the plasticity of advanced high-strength steels (AHSSs). In this study, the hot stamping and partitioning process of advanced high-strength steel 30CrMnSi2Nb is investigated with a hot stamping mold. Given the specific partitioning time and temperature, the influence of quenching temperature on the volume fraction of microstructure evolution and mechanical properties of the above steel are studied in detail. In addition, a model for quenching and partitioning process is applied to predict the carbon diffusion and interface migration during partitioning, which determines the retained austenite volume fraction and final properties of the part. The predicted trends of the retained austenite volume fraction agree with the experimental results. In both cases, the volume fraction of retained austenite increases first and then decreases with the increasing quenching temperature. The optimal quenching temperature is approximately 290 °C for 30CrMnSi2Nb with the partition conditions of 425 °C and 20 seconds. It is suggested that the model can be used to help determine the process parameters to obtain retained austenite as much as possible.

  6. Analytical support for the preparation of bundle test QUENCH-10 on air ingress

    International Nuclear Information System (INIS)

    Birchley, J.; Haste, T.; Homann, C.; Hering, W.

    2005-07-01

    Bundle test QUENCH-10 is dedicated to study air ingress with subsequent water quench during a supposed accident in a spent fuel storage tank. It was proposed by AEKI, Budapest, Hungary and was performed on 21 July 2004 in the QUENCH facility at Forschungszentrum Karlsruhe. Preparation of the test is based on common analytical work at Forschungszentrum Karlsruhe and Paul Scherrer Institut, Villigen, Switzerland, mainly with the severe accident codes SCDAP/RELAP5 and MELCOR, to derive the protocol for the essential test phases, namely pre-oxidation, air ingress and quench phase. For issues that could not be tackled by this computational work, suggestions for the test conduct were made and applied during the test. Improvements of the experimental set-up and the test conduct were suggested and largely applied. In SCDAP/RELAP5, an error was found: for thick oxide scales, the output value of the oxide scale is sensibly underestimated. For the aims of the test preparation, its consequences could be taken into account. Together with the related computational and other analytical support by the engaged institutions the test is co-financed as test QUENCH-L1 by the European Community under the Euratom Fifth Framework Programme on Nuclear Fission Safety 1998 - 2002 (LACOMERA Project, contract No. FIR1-CT2002-40158). (orig.)

  7. On the quench sensitivity of 7010 aluminum alloy forgings in the overaged condition

    Energy Technology Data Exchange (ETDEWEB)

    Tiryakioğlu, Murat, E-mail: m.tiryakioglu@unf.edu [School of Engineering, University of North Florida, Jacksonville, FL 32224 (United States); Robinson, Jeremy S. [Department of Mechanical, Aeronautical and Biomedical Engineering, University of Limerick, Limerick (Ireland); Eason, Paul D. [School of Engineering, University of North Florida, Jacksonville, FL 32224 (United States)

    2014-11-17

    The quench sensitivity of an overaged 7010 alloy forging was characterized by tensile and Vickers hardness tests, as well as scanning electron microscopy. Longitudinal tensile specimens, excised from a rectilinear open die forging were cooled from the solution treatment temperature following thirty-two different cooling paths including interrupted and delayed quenches. SEM analysis of the microstructure showed that quench precipitates were (i) Al{sub 2}CuMg (S) which nucleated heterogeneously on grain boundaries and (ii) Mg(Zn,Cu,Al){sub 2} (η) on grain boundaries, dispersoid bands, subgrain boundaries as well as in the aluminum matrix. The quench sensitivity of the alloy's yield strength and Vickers hardness was modeled simultaneously by quadruple-C curves, using an improved methodology for Quench Factor Analysis. The four C-curves used in the model represented loss of solute by (i) precipitation of S on grain boundaries, and precipitation of η (ii) on grain boundaries and dispersoid bands, (iii) on subgrain boundaries and (iv) in the matrix. The model yielded coefficient of determination (R{sup 2}) values of 0.967 and 0.974 for yield strength and Vickers hardness, respectively. The model and the implications of the results are discussed in this paper.

  8. Results from heater-induced quenches of A 4.5 m Reference Design D dipole for the SSC

    International Nuclear Information System (INIS)

    Ganetis, G.; Prodell, A.

    1986-01-01

    Quench studies were performed using a 4.5 m long Reference Design D, SSC dipole to determine the temperature rise of the magnet conductor during a quench by measuring the resistance of the conductor cable in the immediate vicinity of the quench. The single bore magnet was wound with improved NbTi conductor in a 2-layer cosine θ coil configuration of 4.0 cm inner diameter. Eight pairs of voltage taps were installed at various locations on the right side of the inner coil of the magnet. ''Spot'' heaters were centrally located between the voltage taps of 4 of these pairs on the midplane turn of the inner coil to initiate magnet quenches. A redundant array of voltage taps and heaters was also installed on the left side of the inner coil. The resistance of the conductor was obtained from observations of the current and voltage during a magnet quench. The temperature of the conductor was then determined by comparing its resistance to an R vs T curve appropriate for the conductor. The quantity ∫ I 2 dt and the temperature, T, are presented as a function of current, and the maximum conductor temperature is shown as a function of ∫ I 2 dt. Measured longitudinal and azimuthal quench propagation velocities are also presented as a function of magnet current, and the temperatures at several locations on the inner magnet coil are plotted as a function of the time after a quench was initiated

  9. IMPROVEMENT SUPPORT RESEARCH OF LOCAL DISASTER PREVENTION POWER USING THE FIRE SPREADING SIMULATION SYSTEM IN CASE OF A BIG EARTHQUAKE

    Science.gov (United States)

    Futagami, Toru; Omoto, Shohei; Hamamoto, Kenichirou

    This research describes the risk communication towards improvement in the local disaster prevention power for Gobusho town in Marugame city which is only a high density city area in Kagawa Pref. Specifically, the key persons and authors of the area report the practice research towards improvement in the local disaster prevention power by the PDCA cycle of the area, such as formation of local voluntary disaster management organizations and implementation of an emergency drill, applying the fire spreading simulation system in case of a big earthquake. The fire spreading simulation system in case of the big earthquake which authors are developing describes the role and subject which have been achieved to BCP of the local community as a support system.

  10. Chemical reactivation of quenched fluorescent protein molecules enables resin-embedded fluorescence microimaging

    Science.gov (United States)

    Xiong, Hanqing; Zhou, Zhenqiao; Zhu, Mingqiang; Lv, Xiaohua; Li, Anan; Li, Shiwei; Li, Longhui; Yang, Tao; Wang, Siming; Yang, Zhongqin; Xu, Tonghui; Luo, Qingming; Gong, Hui; Zeng, Shaoqun

    2014-06-01

    Resin embedding is a well-established technique to prepare biological specimens for microscopic imaging. However, it is not compatible with modern green-fluorescent protein (GFP) fluorescent-labelling technique because it significantly quenches the fluorescence of GFP and its variants. Previous empirical optimization efforts are good for thin tissue but not successful on macroscopic tissue blocks as the quenching mechanism remains uncertain. Here we show most of the quenched GFP molecules are structurally preserved and not denatured after routine embedding in resin, and can be chemically reactivated to a fluorescent state by alkaline buffer during imaging. We observe up to 98% preservation in yellow-fluorescent protein case, and improve the fluorescence intensity 11.8-fold compared with unprocessed samples. We demonstrate fluorescence microimaging of resin-embedded EGFP/EYFP-labelled tissue block without noticeable loss of labelled structures. This work provides a turning point for the imaging of fluorescent protein-labelled specimens after resin embedding.

  11. Comparison of radiation and quenching rate effects on the structure of a sodium borosilicate glass

    International Nuclear Information System (INIS)

    Peuget, Sylvain; Maugeri, Emilio-Andrea; Mendoza, Clement; Fares, Toby; Bouty, Olivier; Jegou, Christophe; Charpentier, Thibault; Moskura, Melanie

    2013-01-01

    The effects of quenching rate and irradiation on the structure of a sodium borosilicate glass were compared using 29 Si, 11 B, and 23 Na nuclear magnetic resonance and Raman spectroscopy. Quenching rate ranging from 0.1 to 3 * 10 4 K min -1 was studied. Various irradiation conditions were performed, i.e. gold-ion irradiation in a multi-energy mode (from 1 to 6.75 MeV), and Kr and Xe ion irradiations with energy of 74 and 92 MeV, respectively. In pile irradiation with thermal neutron flux was performed as well, to study the effect of alpha radiation from the nuclear reaction 10 B(n,α) 7 Li. Both irradiation and high quenching rate induce similar local order modification of the glass structure, mainly a decrease of the mean boron coordination and an increase of Q 3 units. Nevertheless, the variations observed under irradiation are more pronounced than the ones induced by the quenching rate. Moreover, some important modifications of the glass medium range order, i.e. the emergence of the D2 band associated to three members silica rings and a modification of the Si-O-Si angle distribution were only noticed after irradiation. These results suggest that the irradiated structure is certainly not exactly the one obtained by a rapidly quenched equilibrated melt, but rather a more disordered structure that was weakly relaxed during the very rapid quenching phase following the energy deposition step. Raman spectroscopy showed a similar irradiated structure whereas the glass evolutions were controlled by the electronic energy loss in the ion track formation regime for Kr-ion irradiation or by the nuclear energy loss for Au and OSIRIS irradiation. The similar irradiated structure despite different irradiation routes, suggests that the final structural state of this sodium borosilicate glass is mainly controlled by the glass reconstruction after the energy deposition step. (authors)

  12. Fluorescence quenching based alkaline phosphatase activity detection.

    Science.gov (United States)

    Mei, Yaqi; Hu, Qiong; Zhou, Baojing; Zhang, Yonghui; He, Minhui; Xu, Ting; Li, Feng; Kong, Jinming

    2018-01-01

    Simple and fast detection of alkaline phosphatase (ALP) activity is of great importance for diagnostic and analytical applications. In this work, we report a turn-off approach for the real-time detection of ALP activity on the basis of the charge transfer induced fluorescence quenching of the Cu(BCDS) 2 2- (BCDS = bathocuproine disulfonate) probe. Initially, ALP can enzymatically hydrolyze the substrate ascorbic acid 2-phosphate to release ascorbic acid (AA). Subsequently, the AA-mediated reduction of the Cu(BCDS) 2 2- probe, which displays an intense photoluminescence band at the wavelength of 402nm, leads to the static quenching of fluorescence of the probe as a result of charge transfer. The underlying mechanism of the fluorescence quenching was demonstrated by quantum mechanical calculations. The Cu(BCDS) 2 2- probe features a large Stokes shift (86nm) and is highly immune to photo bleaching. In addition, this approach is free of elaborately designed fluorescent probes and allows the detection of ALP activity in a real-time manner. Under optimal conditions, it provides a fast and sensitive detection of ALP activity within the dynamic range of 0-220mUmL -1 , with a detection limit down to 0.27mUmL -1 . Results demonstrate that it is highly selective, and applicable to the screening of ALP inhibitors in drug discovery. More importantly, it shows a good analytical performance for the direct detection of the endogenous ALP levels of undiluted human serum and even whole blood samples. Therefore, the proposed charge transfer based approach has great potential in diagnostic and analytical applications. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Quenching simulation of steel grinding balls

    Energy Technology Data Exchange (ETDEWEB)

    Zapata-Hernandez, O.; Reyes, L. A.; Camurri, C.; Carrasco, C.; Garza-Monte-de-Oca, F.; Colas, R.

    2015-07-01

    The phase transformations of high carbon steel during quenching and equalizing were modelled using commercial computer packages based on the finite element method and the kinetic transformation of steel. The model was used to predict the temperature and microstructural changes taking place within balls of two different sizes that are used for grinding mineral ores. A good correlation between the temperatures measured by inserted thermocouples and those predicted by the model was obtained after modifying the thermal conductivity of the steel within the temperature domain at which mixed phases are present. The phase transformations predicted were confirmed by metallographic analyses. (Author)

  14. A simple holographic scenario for gapped quenches

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, Esperanza; Bosch, Guillermo Milans del [Instituto de Física Teórica IFT UAM/CSIC, Universidad Autónoma de Madrid,28049 Cantoblanco, Madrid (Spain)

    2017-02-24

    We construct gravitational backgrounds dual to a family of field theories parameterized by a relevant coupling. They combine a non-trivial scalar field profile with a naked singularity. The naked singularity is necessary to preserve Lorentz invariance along the boundary directions. The singularity is however excised by introducing an infrared cutoff in the geometry. The holographic dictionary associated to the infrared boundary is developed. We implement quenches between two different values of the coupling. This requires considering time dependent boundary conditions for the scalar field both at the AdS boundary and the infrared wall.

  15. Quenched random-bond ising ferromagnet

    International Nuclear Information System (INIS)

    Sarmento, E.F.; Honmura, R.; Tsallis, C.; Centro Brasileiro de Pesquisas Fisicas, Rio de Janeiro)

    1984-01-01

    A effective-field framework which, without mathematical complexities, enables the calculation of the phase diagram (and magnetization) associated with a quenched bond-mixed spin - 1/2 Ising model in an anisotropic simple cubic lattice have been recently introduced. The case corresponding to anisotropic coupling constants but isotropic concentrations was discussed in detail. Herein the case corresponding to isotropic coupling constants but anisotropic concentrations is discussed. A certain amount of interesting phase diagrams are exhibited; whenever comparison with available data is possible, the present results provide a satisfactory qualitative (and to a certain extent quantitative) agreement. (Author) [pt

  16. Improving infant and young child feeding practices through nutrition education with local resources

    International Nuclear Information System (INIS)

    Jordan, Irmgard; Kuchenbecker, Judith; Reinbott, Anika; Krawinkel, Michael B; Muehlhoff, Ellen

    2014-01-01

    Full text: Poor nutritional status in early infancy is associated with growth faltering and increased risk for morbidity. Main causes for undernutrition are a diet poor in quality and quantity, feeding practices, and hygiene. Programmes emphasize on affordable ways for improving diets for low-income families. Little is known about the period needed for behaviour changes. Longitudinal studies were conducted in Malawi and Cambodia looking at infant and young child feeding as well as growth of children below two years. At baseline 6-9 months old children and their caregivers participating in a nutrition education(NE) program of FAO were invited. The recruited children were matched by age (days) and sex with children living in an area without NE (control). Baseline data was collected prior the NE carried out by trained volunteers twice a month based on locally adopted teaching materials. The children and their caregivers were visited every three months for a total period of 12 months. At baseline the mean age of the children in Malawi was 227 days, all breastfed (n = 149). In Cambodia the mean age was 230 days and 90% of them were still breastfed (n = 96). The mean HAZ was -1.53 in Malawi and -0.87 in Cambodia. Minimum acceptable diet(MAD) was received by 42% and 34% of the children in the intervention areas of Malawi and Cambodia respectively. After three months MAD was achieved by 88% in Malawi and 45% in Cambodia. The rates in the control area in Malawi increased as well from 22% at baseline to 52% three months later. A similar change could be observed in Cambodia with 28% of the children receiving MAD at baseline and 38% three months later. Hygiene behaviour was one focus of the NE in both countries. In Malawi soap usage before feeding the child increased to 32% (p< 0.001), and before food preparation to 33% (both p < 0.001). Also washing before eating the food increased to 22%. In the control area no significant changes in terms of soap usage could be observed. In

  17. Improving peak local SAR prediction in parallel transmit using in situ S-matrix measurements.

    Science.gov (United States)

    Restivo, Matthew; Raaijmakers, Alexander; van den Berg, Cornelis; Luijten, Peter; Hoogduin, Hans

    2017-05-01

    Peak local specific absorption rate (pSAR10g) is an important parameter used to determine patient safety during radiofrequency transmission. pSAR10g predictions for parallel transmit MRI are affected by the level of coupling exhibited by a modeled array in the simulation environment. However, simulated array coupling is rarely equal to the physical array coupling. Accurately simulating the physical array coupling may improve the accuracy of predicted SAR levels. The scattering parameter matrix (S-matrix) of a prototype 4-channel array was measured in situ using directional couplers installed on a 7T scanner. Agreement between the simulated and measured S-matrix was achieved by using network co-simulation with a modified cost function. B1+ maps acquired in a phantom were compared to B1+ distributions determined from simulations. The modified co-simulation technique forces the simulations to have S-matrices similar to the measured values. A comparison of realistically versus ideally simulated coupling conditions shows that ideally simulated coupling can result in large ( > 40%) error in pSAR10g predictions, even when the array is reasonably tuned. The simulated B1+ distributions match the measured B1+ distributions better when the coupling is accurately simulated. Considering the measured array coupling matrix in numerical simulations eliminates a potential confound in pSAR10g prediction. Magn Reson Med 77:2040-2047, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  18. Community-based grain banks using local foods for improved infant and young child feeding in Ethiopia.

    Science.gov (United States)

    Roche, Marion L; Sako, Binta; Osendarp, Saskia J M; Adish, Abdul A; Tolossa, Azeb L

    2017-04-01

    The first thousand days of a child's life are critical for ensuring adequate nutrition to enable optimal health, development and growth. Inadequate infant and young child feeding (IYCF) practices likely contribute to Ethiopia's concerning malnutrition situation. Development partners in four regions of Ethiopia implemented community production of complementary food with women's groups processing local grains and legumes at grain banks to improve availability, accessibility, dietary diversity and timely introduction of complementary foods. The objective of this study was to establish the acceptability, perceived impact, feasibility and required inputs to sustain local grain bank interventions to improve IYCF. A subsidized barter system was used by mothers in the rural communities, and flour was sold in the semi-urban context. Purposive sampling guided the qualitative study design and selection of project stakeholders. A total of 51 key informant interviews and 33 focus group discussions (n = 237) were conducted. The grain bank flour was valued for its perceived diverse local ingredients; while the project was perceived as creating labour savings for women. The grain bank flour offered the potential to contribute to improved IYCF; however, further dietary modification or fortification is needed to improve the micronutrient content. Dependence upon external inputs to subsidize the barter model and the reliance on volunteer labour from women's groups in the rural context are the greatest risks to sustainability. This intervention illustrates how integrated agricultural and health interventions leveraging local production can appeal to diverse stakeholders as an acceptable approach to improve IYCF. © 2015 John Wiley & Sons Ltd.

  19. Quench dynamics in SRF cavities: can we locate the quench origin with 2nd sound?

    Energy Technology Data Exchange (ETDEWEB)

    Maximenko, Yulia; /Moscow, MIPT; Segatskov, Dmitri A.; /Fermilab

    2011-03-01

    A newly developed method of locating quenches in SRF cavities by detecting second-sound waves has been gaining popularity in SRF laboratories. The technique is based on measurements of time delays between the quench as determined by the RF system and arrival of the second-sound wave to the multiple detectors placed around the cavity in superfluid helium. Unlike multi-channel temperature mapping, this approach requires only a few sensors and simple readout electronics; it can be used with SRF cavities of almost arbitrary shape. One of its drawbacks is that being an indirect method it requires one to solve an inverse problem to find the location of a quench. We tried to solve this inverse problem by using a parametric forward model. By analyzing the data we found that the approximation where the second-sound emitter is a near-singular source does not describe the physical system well enough. A time-dependent analysis of the quench process can help us to put forward a more adequate model. We present here our current algorithm to solve the inverse problem and discuss the experimental results.

  20. Hα3: an Hα imaging survey of HI selected galaxies from ALFALFA. VI. The role of bars in quenching star formation from z = 3 to the present epoch

    Science.gov (United States)

    Gavazzi, G.; Consolandi, G.; Dotti, M.; Fanali, R.; Fossati, M.; Fumagalli, M.; Viscardi, E.; Savorgnan, G.; Boselli, A.; Gutiérrez, L.; Hernández Toledo, H.; Giovanelli, R.; Haynes, M. P.

    2015-08-01

    A growing body of evidence indicates that the star formation rate per unit stellar mass (sSFR) decreases with increasing mass in normal main-sequence star-forming galaxies. Many processes have been advocated as being responsible for this trend (also known as mass quenching), e.g., feedback from active galactic nuclei (AGNs), and the formation of classical bulges. In order to improve our insight into the mechanisms regulating the star formation in normal star-forming galaxies across cosmic epochs, we determine a refined star formation versus stellar mass relation in the local Universe. To this end we use the Hα narrow-band imaging follow-up survey (Hα3) of field galaxies selected from the HI Arecibo Legacy Fast ALFA Survey (ALFALFA) in the Coma and Local superclusters. By complementing this local determination with high-redshift measurements from the literature, we reconstruct the star formation history of main-sequence galaxies as a function of stellar mass from the present epoch up to z = 3. In agreement with previous studies, our analysis shows that quenching mechanisms occur above a threshold stellar mass Mknee that evolves with redshift as ∝ (1 + z)2. Moreover, visual morphological classification of individual objects in our local sample reveals a sharp increase in the fraction of visually classified strong bars with mass, hinting that strong bars may contribute to the observed downturn in the sSFR above Mknee. We test this hypothesis using a simple but physically motivated numerical model for bar formation, finding that strong bars can rapidly quench star formation in the central few kpc of field galaxies. We conclude that strong bars contribute significantly to the red colors observed in the inner parts of massive galaxies, although additional mechanisms are likely required to quench the star formation in the outer regions of massive spiral galaxies. Intriguingly, when we extrapolate our model to higher redshifts, we successfully recover the observed

  1. System and method for quench protection of a superconductor

    Science.gov (United States)

    Huang, Xianrui; Sivasubramaniam, Kiruba Haran; Bray, James William; Ryan, David Thomas

    2008-03-11

    A system and method for protecting a superconductor from a quench condition. A quench protection system is provided to protect the superconductor from damage due to a quench condition. The quench protection system comprises a voltage detector operable to detect voltage across the superconductor. The system also comprises a frequency filter coupled to the voltage detector. The frequency filter is operable to couple voltage signals to a control circuit that are representative of a rise in superconductor voltage caused by a quench condition and to block voltage signals that are not. The system is operable to detect whether a quench condition exists in the superconductor based on the voltage signal received via the frequency filter and to initiate a protective action in response.

  2. Quorum Quenching Revisited—From Signal Decays to Signalling Confusion

    Directory of Open Access Journals (Sweden)

    Kok-Gan Chan

    2012-04-01

    Full Text Available In a polymicrobial community, while some bacteria are communicating with neighboring cells (quorum sensing, others are interrupting the communication (quorum quenching, thus creating a constant arms race between intercellular communication. In the past decade, numerous quorum quenching enzymes have been found and initially thought to inactivate the signalling molecules. Though this is widely accepted, the actual roles of these quorum quenching enzymes are now being uncovered. Recent evidence extends the role of quorum quenching to detoxification or metabolism of signalling molecules as food and energy source; this includes “signalling confusion”, a term coined in this paper to refer to the phenomenon of non-destructive modification of signalling molecules. While quorum quenching has been explored as a novel anti-infective therapy targeting, quorum sensing evidence begins to show the development of resistance against quorum quenching.

  3. MultiLoc2: integrating phylogeny and Gene Ontology terms improves subcellular protein localization prediction

    Directory of Open Access Journals (Sweden)

    Kohlbacher Oliver

    2009-09-01

    Full Text Available Abstract Background Knowledge of subcellular localization of proteins is crucial to proteomics, drug target discovery and systems biology since localization and biological function are highly correlated. In recent years, numerous computational prediction methods have been developed. Nevertheless, there is still a need for prediction methods that show more robustness and higher accuracy. Results We extended our previous MultiLoc predictor by incorporating phylogenetic profiles and Gene Ontology terms. Two different datasets were used for training the system, resulting in two versions of this high-accuracy prediction method. One version is specialized for globular proteins and predicts up to five localizations, whereas a second version covers all eleven main eukaryotic subcellular localizations. In a benchmark study with five localizations, MultiLoc2 performs considerably better than other methods for animal and plant proteins and comparably for fungal proteins. Furthermore, MultiLoc2 performs clearly better when using a second dataset that extends the benchmark study to all eleven main eukaryotic subcellular localizations. Conclusion MultiLoc2 is an extensive high-performance subcellular protein localization prediction system. By incorporating phylogenetic profiles and Gene Ontology terms MultiLoc2 yields higher accuracies compared to its previous version. Moreover, it outperforms other prediction systems in two benchmarks studies. MultiLoc2 is available as user-friendly and free web-service, available at: http://www-bs.informatik.uni-tuebingen.de/Services/MultiLoc2.

  4. Color quench correction for low level Cherenkov counting

    International Nuclear Information System (INIS)

    Tsroya, S.; Pelled, O.; German, U.; Marco, R.; Katorza, E.; Alfassi, Z.B.

    2009-01-01

    The Cherenkov counting efficiency varies strongly with color quenching, thus correction curves must be used to obtain correct results. The external 152 Eu source of a Quantulus 1220 TM liquid scintillation counting (LSC) system was used to obtain a quench indicative parameter based on spectra area ratio. A color quench correction curve for aqueous samples containing 90 Sr/ 90 Y was prepared. The main advantage of this method over the common spectra indicators is its usefulness also for low level Cherenkov counting.

  5. Amplified Luminescence Quenching of Phosphorescent Metal–Organic Frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Kent, Caleb A. [Department of Chemistry,; Liu, Demin [Department of Chemistry,; Meyer, Thomas J. [Department of Chemistry,; Lin, Wenbin [Department of Chemistry,

    2012-02-22

    Amplified luminescence quenching has been demonstrated in metal–organic frameworks (MOFs) composed of Ru(II)-bpy building blocks with long-lived, largely triplet metal-to-ligand charge-transfer excited states. Strong non-covalent interactions between the MOF surface and cationic quencher molecules coupled with rapid energy transfer through the MOF microcrystal facilitates amplified quenching with a 7000-fold enhancement of the Stern–Völmer quenching constant for methylene blue compared to a model complex.

  6. Kaon B-parameter from quenched domain-wall QCD

    International Nuclear Information System (INIS)

    Ali Khan, A.; Aoki, S.; Aoki, Y.; Burkhalter, R.; Ejiri, S.; Fukugita, M.; Hashimoto, S.; Ishizuka, N.; Iwasaki, Y.; Izubuchi, T.; Kanaya, K.; Kaneko, T.; Kuramashi, Y.; Nagai, K.-I.; Noaki, J.; Okawa, M.; Shanahan, H.P.; Taniguchi, Y.; Ukawa, A.; Yoshie, T.

    2001-01-01

    We report on a calculation of B K with domain wall fermion action in quenched QCD. Simulations are made with a renormalization group improved gauge action at β = 2.6 and 2.9 corresponding to a -1 ∼ 2GeV and 3GeV. Effects due to finite fifth dimensional size N 5 and finite spatial size N σ are examined in detail. Matching to the continuum operator is made perturbatively at one loop order. We obtain B K (μ = 2GeV) 0.5746(61), where the error is statistical only, as an estimate of the continuum value in the MS-bar scheme with naive dimensional regularization. This value is smaller but consistent with B K (μ = 2GeV) = 0.628(42) obtained by the JLQCD Collaboration using the Kogut-Susskind quark action. Results for strange quark mass are also reported

  7. Improvement of magnetic hardness at finite temperatures: Ab initio disordered local-moment approach for YCo5

    Science.gov (United States)

    Matsumoto, Munehisa; Banerjee, Rudra; Staunton, Julie B.

    2014-08-01

    Temperature dependence of the magnetocrystalline anisotropy energy and magnetization of the prototypical rare-earth magnet YCo5 is calculated from first principles, utilizing the relativistic disordered local-moment approach. We discuss a strategy to enhance the finite-temperature anisotropy field by hole doping, paving the way for an improvement of the coercivity near room temperature or higher.

  8. Deposition-induced photoluminescence quenching of tris-(8-hydroxyquinoline) aluminum

    Science.gov (United States)

    Choong, V.-E.; Park, Y.; Shivaparan, N.; Tang, C. W.; Gao, Y.

    1997-08-01

    Ca, Ag, and Ge atoms quench the photoluminescence (PL) of an organic thin film, tris-(8-hydroxyquinoline) aluminum (Alq3), a model organic material for organic light emitting diodes. The observed PL quenching behavior was similar for all three elements, independent of their metallic nature. Due to strong interactions at the Ca/Alq3 interface, the quenching was much less effective at submonolayer coverages. We have also observed that proper oxidation of Ca at the Ca/Alq3 interface can significantly recover the quenched luminescence of Alq3.

  9. Force cooled quench tanks for the ITER cryogenic system

    Science.gov (United States)

    Kouzmenko, G.; Simon, M.; Saulquin, S.; Buskop, J.; Voigt, T.; Monneret, E.; Grillot, D.; Cursan, M.; Pichot, D.; Demar, G.

    2017-12-01

    The toroidal field magnets of ITER contain over 7 tons of helium. Most of the inventory is expelled from the magnets in case of a quench and it needs to be captured in external storage vessels (Quench Tanks). Force cooled technology with external gas circulation was chosen for these vessels in order to optimize their footprint, risks, and costs. This paper outlines the input data, assumptions, and studies performed in order to choose the most appropriate technology for the Quench Tanks. Further studies to demonstrate feasibility and ensure the required performance, as well as some peculiarities of the design and manufacturing of Quench Tanks are also described.

  10. Learning in Australian local government: A roadmap for improving education & training

    Directory of Open Access Journals (Sweden)

    Ronald Woods

    2016-02-01

    Full Text Available Faced with a context of national and state reform agendas as well as resource scarcity, Australian local government has pressing workforce development issues. This level of government is small in scale, geographically dispersed and subject to variations in state jurisdiction. These factors represent structural constraints to identifying and advocating a national approach for addressing workforce needs such as the provision of tailored education and professional development. This paper documents a sector consultation process exploring education and professional development for local government which aimed to identify needs on both supply and demand sides. The research found that aspirations for education and professional development tailored to the needs of local government aim to support the development of better local governance and leadership, and to address critical skills shortage issues. This may provide empirical grounds for promoting, planning, implementing and evaluating capacity-building initiatives in this third tier of government in the Australian federation.

  11. Improvement of directionality and sound-localization by internal ear coupling in barn owls

    DEFF Research Database (Denmark)

    Wagner, Hermann; Christensen-Dalsgaard, Jakob; Kettler, Lutz

    Mark Konishi was one of the first to quantify sound-localization capabilities in barn owls. He showed that frequencies between 3 and 10 kHz underlie precise sound localization in these birds, and that they derive spatial information from processing interaural time and interaural level differences....... However, despite intensive research during the last 40 years it is still unclear whether and how internal ear coupling contributes to sound localization in the barn owl. Here we investigated ear directionality in anesthetized birds with the help of laser vibrometry. Care was taken that anesthesia...... time difference in the low-frequency range, barn owls hesitate to approach prey or turn their heads when only low-frequency auditory information is present in a stimulus they receive. Thus, the barn-owl's sound localization system seems to be adapted to work best in frequency ranges where interaural...

  12. The improvement of the connections reliability in a local communication system

    International Nuclear Information System (INIS)

    Buisson, J.; Sanchis, P.

    1986-01-01

    The local communication systems used in the management of the industrial processes must fulfil more severe conditions concerning the reliability and safety than those used in bureaucratics. After mentioning the specific requirements the solutions for the realization of a local industrial communication system are presented. Studies to develop an optical fibers coupling system for a linear network used for the transmission in a hostile medium are mentioned

  13. The Inductive Coupling of the Magnets in MICE and its Effect on Quench Protection

    International Nuclear Information System (INIS)

    Green, Michael A.; Witte, Holger

    2005-01-01

    The inductive coupling between various MICE magnet circuits is described. The consequences of this coupling on magnet charging and quenching are discussed. Magnet quench protection is achieved through the use of quench-back. Calculations of the quenching of a magnet due to quench-back resulting from circulating currents induced in the magnet mandrel due to quenching of an adjacent magnet are discussed. This report describes how the MICE magnet channel will react when magnets in that channel are quenched

  14. New, Coupling Loss Induced, Quench Protection System for Superconducting Accelerator Magnets

    CERN Document Server

    Ravaioli, E; Giloux, C; Kirby, G; ten Kate, H H J; Verweij, A P

    2014-01-01

    Email Print Request Permissions Save to Project A new and promising method for the protection of superconducting high-field magnets is developed and tested on the so-called MQXC quadrupole magnet at the CERN magnet test facility. The method relies on a capacitive discharge system inducing, during a few periods, an oscillation of the transport current in the superconducting cable of the coil. The corresponding fast change of the local magnetic field introduces a high coupling-current loss, which, in turn, causes a fast quench of a large fraction of the coil due to enhanced temperature. Results of measured discharges at various levels of transport current are presented and compared to discharges by quenching the coils using conventional quench heaters and an energy extraction system. The hot-spot temperature in the quenching coil is deduced from the coil voltage and current. The results are compared to simulations carried out using a lumped-element dynamic electro-thermal model of the so-called MQX...

  15. Modelling of Quench Limit for Steady State Heat Deposits in LHC Magnets

    CERN Document Server

    Bocian, D; Siemko, A

    2008-01-01

    A quench, the transition of a conductor from the superconducting to the normal conducting state, occurs irreversibly in the accelerator magnets if one of the three parameters: temperature, magnetic field or current density exceeds a critical value. Energy deposited in the superconductor by the particle beams provokes quenches detrimental for the accelerator operation. In particular if particles impacting on the vacuum chamber and their secondary showers depose energy in the magnet coils. The Large Hadron Collider (LHC) nominal beam intensity is 3.2 ldr 10^14 protons. A quench occurs if a fraction of the order of 10^7 protons per second is lost locally. A network model is used to simulate the thermodynamic behaviour of the magnets. The heat flow in the network model was validated with measurements performed in the CERN magnet test facility. A steady state heat flow was introduced in the coil by using the quench heaters implemented in the LHC magnets. The value of the heat source current is determined by the ne...

  16. Enhancing and quenching luminescence with gold nanoparticle films: the influence of substrate on the luminescent properties

    International Nuclear Information System (INIS)

    Guidelli, Eder José; Baffa, Oswaldo; Ramos, Ana Paula

    2016-01-01

    Gold nanoparticle (AuNP) films were sputtered over glass and aluminum substrates to enhance optically stimulated luminescence (OSL), a luminescent technique employed for radiation detection, from x-ray irradiated NaCl nanocrystals. The AuNP films deposited over glass led to enhanced-OSL emission, whereas the AuNP films deposited on aluminum substrates quenched the OSL emission. The enhanced-OSL intensity is proportional to the optical density of the film's plasmon resonance band at the stimulation wavelength. For the case of the AuNP/aluminum films, the luminescence quenching diminishes, and OSL intensity partially recovers upon increasing the distance between the AuNPs and the aluminum substrates, and between the luminescent nanocrystals and the AuNP films. These results suggest that plasmonic interactions between the emitter nanocrystals, the localized surface plasmons (LSP) of the AuNPs, and the substrate are responsible for the OSL enhancement and quenching. In this sense, the substrate dictates whether LSP relaxation occurs by radiative or non-radiative transisitions, leading to enhanced or quenched OSL, respectively. Therefore, besides showing that AuNP films can enhance and/or tune the sensitivity of luminescent radiation detectors, and demonstrating OSL as a new technique to investigate mechanisms of plasmon-enhanced luminescence, these results bring insights on how substrates strongly modify the optical properties of AuNP films. (paper)

  17. Short-term weight loss attenuates local tissue inflammation and improves insulin sensitivity without affecting adipose inflammation in obese mice.

    Science.gov (United States)

    Jung, Dae Young; Ko, Hwi Jin; Lichtman, Eben I; Lee, Eunjung; Lawton, Elizabeth; Ong, Helena; Yu, Kristine; Azuma, Yoshihiro; Friedline, Randall H; Lee, Ki Won; Kim, Jason K

    2013-05-01

    Obesity is a major cause of insulin resistance, and weight loss is shown to improve glucose homeostasis. But the underlying mechanism and the role of inflammation remain unclear. Male C57BL/6 mice were fed a high-fat diet (HFD) for 12 wk. After HFD, weight loss was induced by changing to a low-fat diet (LFD) or exercise with continuous HFD. The weight loss effects on energy balance and insulin sensitivity were determined using metabolic cages and hyperinsulinemic euglycemic clamps in awake mice. Diet and exercise intervention for 3 wk caused a modest weight loss and improved glucose homeostasis. Weight loss dramatically reduced local inflammation in skeletal muscle, liver, and heart but not in adipose tissue. Exercise-mediated weight loss increased muscle glucose metabolism without affecting Akt phosphorylation or lipid levels. LFD-mediated weight loss reduced lipid levels and improved insulin sensitivity selectively in liver. Both weight loss interventions improved cardiac glucose metabolism. These results demonstrate that a short-term weight loss with exercise or diet intervention attenuates obesity-induced local inflammation and selectively improves insulin sensitivity in skeletal muscle and liver. Our findings suggest that local factors, not adipose tissue inflammation, are involved in the beneficial effects of weight loss on glucose homeostasis.

  18. SARNET2 benchmark on air ingress experiments QUENCH-10, -16

    International Nuclear Information System (INIS)

    Fernandez-Moguel, Leticia; Bals, Christine; Beuzet, Emilie; Bratfisch, Christian; Coindreau, Olivia; Hózer, Zoltan; Stuckert, Juri; Vasiliev, Alexander; Vryashkova, Petya

    2014-01-01

    Highlights: • Two similar QUENCH air ingress experiments were analysed with eight different codes. • Eight institutions have participated in the study. • Differences in the code were mostly small to moderate during the pre-oxidation. • Differences in the code were larger during the air phase. • Study has proven that there are physical processes that should be further studied. - Abstract: The QUENCH-10 (Q-10) and QUENCH-16 (Q-16) experiments were chosen as a SARNET2 code benchmark (SARNET2-COOL-D5.4) exercise to assess the status of modelling air ingress sequences and to compare the capabilities of the various codes used for accident analyses, specifically ATHLET-CD (GRS and RUB), ICARE-CATHARE (IRSN), MAAP (EDF), MELCOR (INRNE and PSI), SOCRAT (IBRAE), and RELAP/SCDAPSim (PSI). Both experiments addressed air ingress into an overheated core following earlier partial oxidation in steam. Q-10 was performed with extensive preoxidation, moderate/high air flow rate and high temperatures at onset of reflood (max T pct = 2200 K), while Q-16 was performed with limited preoxidation, low air flow rate and relative low temperatures at reflood initiation (max T pct = 1870 K). Variables relating to the major signatures (thermal response, hydrogen generation, oxide layer development, oxygen and nitrogen consumption and reflood behaviour) were compared globally and/or at selected locations. In each simulation, the same input models and assumptions are used for both experiments, differing only in respect of the boundary conditions. However, some slight idealisations were made to the assumed boundary conditions in order to avoid ambiguities in the code-to-code comparisons; in this way, it was possible to focus more easily on the key phenomena and hence make the results of the exercise more transparent. Remarks are made concerning the capability of physical modelling within the codes, description of the experiment facility and test conduct as specified in the code input

  19. To the question of improvement of hygienic standardization of local impulse vibration in working environment

    Directory of Open Access Journals (Sweden)

    Sova S.G.

    2015-03-01

    Full Text Available The paper analyzes the differences between domestic and European methodology of hygienic standardization of the local impulse vibration. With the assistance of the vibrometer Octava-101-U there were studied hygienic parameters of pulsed local vibrations in mechanical workshops of the State Enterprise "Antonov" and the State Enterprise "Plant 410 civil aviation" according to the procedure set out in SSN 3.3.6.039-99 "State sanitary norms of general and local production vibration". Levels of pulsed local vibration in the workplace of fitter-assemblers and fitters do not exceed the standards of domestic hygiene standards and, at the same time, ten times higher than the exposure limits of the European system of standards “Health and Sufety Executive” (HSE. Discrepancies between national and European system of regulation and assessment of the harmful effects of local vibration can explain the development of early clinical syndromes in workers of vibration-dangerous enterprises, this makes to pical bringing of Ukrainian hygienic standards to European standards.

  20. Hybrid Indoor-Based WLAN-WSN Localization Scheme for Improving Accuracy Based on Artificial Neural Network

    Directory of Open Access Journals (Sweden)

    Zahid Farid

    2016-01-01

    Full Text Available In indoor environments, WiFi (RSS based localization is sensitive to various indoor fading effects and noise during transmission, which are the main causes of localization errors that affect its accuracy. Keeping in view those fading effects, positioning systems based on a single technology are ineffective in performing accurate localization. For this reason, the trend is toward the use of hybrid positioning systems (combination of two or more wireless technologies in indoor/outdoor localization scenarios for getting better position accuracy. This paper presents a hybrid technique to implement indoor localization that adopts fingerprinting approaches in both WiFi and Wireless Sensor Networks (WSNs. This model exploits machine learning, in particular Artificial Natural Network (ANN techniques, for position calculation. The experimental results show that the proposed hybrid system improved the accuracy, reducing the average distance error to 1.05 m by using ANN. Applying Genetic Algorithm (GA based optimization technique did not incur any further improvement to the accuracy. Compared to the performance of GA optimization, the nonoptimized ANN performed better in terms of accuracy, precision, stability, and computational time. The above results show that the proposed hybrid technique is promising for achieving better accuracy in real-world positioning applications.

  1. Daily Isocenter Correction With Electromagnetic-Based Localization Improves Target Coverage and Rectal Sparing During Prostate Radiotherapy

    International Nuclear Information System (INIS)

    Rajendran, Ramji Ramaswamy; Plastaras, John P.; Mick, Rosemarie; McMichael Kohler, Diane; Kassaee, Alireza; Vapiwala, Neha

    2010-01-01

    Purpose: To evaluate dosimetric consequences of daily isocenter correction during prostate cancer radiation therapy using the Calypso 4D localization system. Methods and Materials: Data were analyzed from 28 patients with electromagnetic transponders implanted in their prostates for daily target localization and tracking. Treatment planning isocenters were recorded based on the values of the vertical, longitudinal, and lateral axes. Isocenter location obtained via alignment with skin tattoos was compared with that obtained via the electromagnetic localization system. Daily isocenter shifts, based on the isocenter location differences between the two alignment methods in each spatial axis, were calculated for each patient over their entire course. The mean isocenter shifts were used to determine dosimetric consequences of treatment based on skin tattoo alignments alone. Results: The mean += SD of the percentages of treatment days with shifts beyond += 0.5 cm for vertical, longitudinal and lateral shifts were 62% += 28%, 35% += 26%, and 38% +=21%, respectively. If daily electromagnetic localization was not used, the excess in prescribed dose delivered to 70% of the rectum was 10 Gy and the deficit in prescribed dose delivered to 95% of the planning target volume was 10 Gy. The mean isocenter shift was not associated with the volumes of the prostate, rectum, or bladder, or with patient body mass index. Conclusions: Daily isocenter localization can reduce the treatment dose to the rectum. Correcting for this variability could lead to improved dose delivery, reduced side effects, and potentially improved treatment outcomes.

  2. Many-Particle Dephasing after a Quench

    Science.gov (United States)

    Kiendl, Thomas; Marquardt, Florian

    2017-03-01

    After a quench in a quantum many-body system, expectation values tend to relax towards long-time averages. However, temporal fluctuations remain in the long-time limit, and it is crucial to study the suppression of these fluctuations with increasing system size. The particularly important case of nonintegrable models has been addressed so far only by numerics and conjectures based on analytical bounds. In this work, we are able to derive analytical predictions for the temporal fluctuations in a nonintegrable model (the transverse Ising chain with extra terms). Our results are based on identifying a dynamical regime of "many-particle dephasing," where quasiparticles do not yet relax but fluctuations are nonetheless suppressed exponentially by weak integrability breaking.

  3. Holography of radiation and jet quenching

    International Nuclear Information System (INIS)

    Sin, S.-J.; Zahed, I.

    2004-07-01

    We study the on-linear propagation of radiation in N=4 SYM at zero and finite temperature using the refined radius/scale duality in AdS/CFT. We find that at finite temperature, the radiation stalls at a distance of 1/πT with a natural geometric and holographic interpretation. Indeed, the stalling is the holographic analogue of the gravitational in-fall of light towards the black hole in the bulk. We show that in the strongly interacting finite temperature medium, radiation can reach much farther than the static force. We suggest that these results are relevant for jet quenching by a strongly coupled quark-gluon liquid as currently probed in heavy ion colliders at RHIC. In particular, colored jets cannot make it beyond 1/3 fin at RHIC whatever their energy. (author)

  4. A perturbative framework for jet quenching

    CERN Document Server

    Zapp, Korinna C; Wiedemann, Urs A

    2013-01-01

    We present a conceptually new framework for describing jet evolution in the dense medium produced in ultra-relativistic nucleus-nucleus collisions using perturbative QCD and its implementation into the Monte Carlo event generator JEWEL. The rescattering of hard partons in the medium is modelled by infrared continued pQCD matrix elements supplemented with parton showers. The latter approximate higher order real-emission matrix elements and thus generate medium-induced gluon emissions. The interplay between different emissions is governed by their formation times. The destructive interference between subsequent scattering processes, the non-Abelian version of the Landau-Pomeranchuk-Migdal effect, is also taken into account. In this way the complete radiation pattern is consistently treated in a uniform way. Results obtained within this minimal and theoretically well constrained framework are compared with a variety of experimental data susceptible to jet-quenching effects at both RHIC and the LHC. Overall, a go...

  5. Thermal quenching of luminescence processes in feldspars

    DEFF Research Database (Denmark)

    Poolton, N.R.J.; Bøtter-Jensen, L.; Duller, G.A.T.

    1995-01-01

    of these processes is, in general, thermally dependent, and leads either to enhancement or quenching of the luminescence with increasing temperature. Previous studies have measured the combined thermal activation characteristics of all three processes, and show a strong dependence on stimulation energy....... In this article, an initial attempt is made to isolate only the recombination part of the luminescence cycle, and determine its thermal characteristics separately. A Variety of luminescence transitions are examined in a range of both alkali and plagioclase feldspars; three distinct emission types are identified...... of the defect. The third category is the most difficult to analyse since it involves irreversible changes in the luminescence characteristics with increasing temperature; we consider these to be due to thermally-induced destruction or creation of luminescence centres. Most of the alkali and plagioclase...

  6. AGN Feedback and Its Quenching Efficiency

    Directory of Open Access Journals (Sweden)

    Francoise Combes

    2017-09-01

    Full Text Available In the last decade, observations have accumulated on gas outflows in galaxies, and in particular massive molecular ones. The mass outflow rate is estimated between 1 and 5 times the star formation rate. For the highest maximal velocities, they are driven by AGN; these outflows are therefore a clear way to moderate or suppress star formation. Some of the most convincing examples at low redshift come from the radio mode, when the radio jets are inclined toward the galaxy plane, or expand in the hot intra-cluster medium, in cool core clusters. However, AGN feedback can also be positive in many occasions, and the net effect is difficult to evaluate. The quenching efficiency is discussed in view of recent observations.

  7. Quenched QED in the chiral limit

    International Nuclear Information System (INIS)

    Vandermark, S.W.

    1993-01-01

    The main goal in this project has been to understand, through analytical methods, whether there could be a continuum limit for QED. This possibility is motivated by recent lattice simulations on quenched QED which apparently exhibit a chiral phase transition at strong coupling in the chiral limit. Another goal is to develop a novel perturbation expansion which may also be usefully applied to other theories. The author begins with the general expression for the chiral order parameter, (bar ψψ), in the quenched limit of euclidean QED, where the number of fermion flavors goes to zero, using the path integral formulation. A cutoff scale, Λ, is introduced into the photon propagator and a new expansion, the open-quotes wormhole expansion,close quotes in powers of Λ 2 /m 2 , where m is the fermion mass, is derived. Graphical rules for the wormhole expansion of left-angle bar ψψ right-angle are described in detail. The author then devises algorithms to generate recursively the graphs at each successive order and to perform the loop momentum integral and γ matrix trace involved in the evaluation of each graph. These algorithms are implemented in Mathmatica and the left-angle bar ψψ right-angle expansion is carried out to order (Λ 2 / m 2 ) 6 . The author employs pade techniques to extrapolate this expansion to the chiral limit (Λ 2 /m 2 → ∞) and looks for a singularity at strong coupling to signal a phase transition. Indications have been found that there may be a phase transition but apparently there are not enough terms in the wormhole expansion to attain stability in our pade analysis. The author therefore cannot conclude that there is a chiral phase transition, although the results are consistent with the existence of one

  8. Structural transformations in quenched Fe-Ga alloys

    International Nuclear Information System (INIS)

    Lograsso, T.A.; Ross, A.R.; Schlagel, D.L.; Clark, A.E.; Wun-Fogle, M.

    2003-01-01

    It has been speculated that the large increase in magnetostriction in Fe-Ga alloys results from local short-range ordering of the Ga atoms along specific crystallographic directions in the disordered Fe structure. The structural transitions associated with different cooling rates from the high temperature disordered state were investigated with X-ray diffraction of oriented single crystals of Fe-19 at% Ga. Results are presented for long-range ordering during slow cooling and indirect evidence of local short-range ordering of Ga atoms in the disordered state when the alloys are quenched is also presented. In the latter case, the short-range ordering of Ga atoms leads to a tetragonal distortion of the lattice. The dependence of the magnetostrictive response of Fe-Ga alloys on thermal history has been found to be directly related to these structural transformations in Fe-19 at% Ga alloys and experimental support for the proposed magnetostriction model based on Ga-Ga pairing along [100] crystallographic directions is presented

  9. Improving the local relevance of large scale water demand predictions: the way forward

    Science.gov (United States)

    Bernhard, Jeroen; Reynaud, Arnaud; de Roo, Ad

    2016-04-01

    Securing adequate availability of fresh water is of vital importance for socio-economic development of present and future Europe. Due to strong heterogeneity in climate conditions, some regions receive an abundant supply of water, where other areas almost completely depend on limited river discharge from upstream catchments. Furthermore, water demand differs greatly between regions due to differences in population density and local presence of intensive water using industries and agriculture. This results in many situations all across Europe where competition between water users translates into relative scarcity and economic damage. Additionally it is expected that inter-related economic and demographic developments, as well as climate change are to only further increase the need for efficient management of our water resources in the future. Successful policy making for such complex problems requires a good understanding of the system and reliable forecasting of conditions. The extent and complexity of the water use system however, stands in high contrast with the poor state of available data and lack of reliable predictions for this multi-disciplinary topic. Although the matching of available water to its demand is a European-wide problem, the amount of data with pan-European coverage is limited and usually with a national resolution at best. This is hindering researchers and policy makers because it usually makes large scale water demand predictions little relevant due to the strong regional heterogenic nature of the problem. We present in our study a first attempt of European-wide water demand predictions based on consistent regional data and econometric methods for the household and industry sector. We gathered data on water consumption, water prices and other relevant variables at the highest spatial detail available from national statistical offices and other organizational bodies. This database provides the most detailed up to date picture of present water

  10. Tissue specific promoters improve the localization of radiation-inducible gene expression

    International Nuclear Information System (INIS)

    Hallahan, Dennis; Kataoka, Yasushi; Kuchibhotla, Jaya; Virudachalam, Subbu; Weichselbaum, Ralph

    1996-01-01

    expression was quantified in vascular endothelial cells from large vessel (HUVEC) and small vessels (HMEC). We found cell-type specificity of radiation-induction. The promoter region from the ELAM gene gave no expression in cells that were not of endothelial cell origin and x-ray-induction of ELAM in the endothelium required the NFkB binding cis-acting element. ELAM induction was achieved at doses as low as 1 Gy, whereas induction of other radiation inducible genes required 5 to 10 Gy. Cells transfected with the minimal promoter (plasmid pTK-CAT) demonstrated no radiation induction. Expression of the CMV-LacZ genetic construct that was used as a negative control in each transfection was not altered by x-irradiation. Moreover, intravenous administration of liposomes containing a reporter gene linked to the ELAM promoter and a transcriptional amplification system were induced specifically at sites of x-irradiation in an animal model. Conclusions: Activation of transcription of the ELAM-1 promoter by ionizing radiation is a means of activating gene therapy within the vascular endothelium and demonstrates the feasibility of treating vascular lesions with noninvasive procedures. Tissue specific promoters (e. g., ELAM-1) combined with radiation inducible gene therapy improves the localization of gene therapy expression. These results have applications in intravascular brachytherapy for the prevention of blood vessel restenosis

  11. Fostering evidence-based quality improvement for patient-centered medical homes: Initiating local quality councils to transform primary care.

    Science.gov (United States)

    Stockdale, Susan E; Zuchowski, Jessica; Rubenstein, Lisa V; Sapir, Negar; Yano, Elizabeth M; Altman, Lisa; Fickel, Jacqueline J; McDougall, Skye; Dresselhaus, Timothy; Hamilton, Alison B

    were critical. In order to successfully facilitate systematic, sustainable primary care quality improvement, regional and executive health care system leaders should engage interdisciplinary practice level leadership in a priority-setting process that encourages frontline innovation and establish local structures such as quality councils to coordinate quality improvement initiatives, ensure accountability, and promote spread of best practices.

  12. Towards improved waste management services by local government – A waste governance perspective

    CSIR Research Space (South Africa)

    Oelofse, Suzanna HH

    2008-11-01

    Full Text Available In terms of the South African Constitution (Act 108of 1996), waste management service delivery is a local government function. The Constitution further gives every person the right to an environment that is not harmful to their health or well...

  13. Improved prognosis for localized malignant lymphomas of the head and neck

    DEFF Research Database (Denmark)

    Aanaes, Kasper; Kristensen, Elisabeth; Ralfkiær, Elisabeth M

    2010-01-01

    to the literature according to the 2001 classification. Methods: We present a retrospective study including a cohort of 100 consecutive patients who had localized malignant lymphoma within the head and neck region diagnosed at a single centre from 2000 to 2007. Results: The histology was revised according...

  14. Identifying Motivation of the Local Governments to Improve the Sustainability Transparency

    Directory of Open Access Journals (Sweden)

    Andrés NAVARRO GALERA

    2015-06-01

    Full Text Available This paper examines the sustainability tran-sparency of governments, i.e., the disclosure of information on the sustainability of their ac-tions. To do so, we identify contributory factors to the online disclosure of environmental, social, economic and general information by local gov-ernments in Nordic countries. Linear regression analysis was used to identify factors inf uencing the online dissemination of government infor-mation on sustainability; a factor analysis, as a precursor to linear regression, led us to reduce 14 explanatory variables to four factors: f nancial risk, demography, professional qualif cations and local government resources. The results obtained show that local f -nancial priorities have a greater impact on the sustainability-related content of governmental websites than does concern for the needs of the population. Furthermore, an organization’s dis-closure of its f nancial risks, together with greater awareness of stakeholders’ demands, could pro-mote transparency in the f eld of environmental, social and economic sustainability, while local demographic characteristics could foster the publication of information on environmental sus-tainability.

  15. Modification of local diets to improve vitamin A, iron and protein ...

    African Journals Online (AJOL)

    The created recipes based on locally available and affordable ingredients have a potential to meet RDAs of vitamin A, iron and protein for children aged 6 to 23 months in the banana-based system and other communities in Africa with the same settings. The communities need to establish home gardens so as to use ...

  16. Improving peak local SAR prediction in parallel transmit using in situ S-matrix measurements

    NARCIS (Netherlands)

    Restivo, Matthew; Raaijmakers, AJE; van den Berg, CAT; Luijten, Peter; Hoogduin, Hans

    PURPOSE: Peak local specific absorption rate (pSAR10g) is an important parameter used to determine patient safety during radiofrequency transmission. pSAR10g predictions for parallel transmit MRI are affected by the level of coupling exhibited by a modeled array in the simulation environment.

  17. Improving SCADA security of a local process with a power grid model

    NARCIS (Netherlands)

    Chromik, Justyna Joanna; Remke, Anne Katharina Ingrid; Haverkort, Boudewijn R.H.M.

    Security of networks controlling smart grids is an important subject. The shift of the power grid towards a smart grid results in more distributed control functions, while intrusion detection of the control network mostly remains centrally based. Moreover, existing local (host-based) intrusion

  18. Improved open-sun drying method for local swamp rice in Uganda ...

    African Journals Online (AJOL)

    “Kaiso” and “Supa” are the main local swamp-rice (Oryza Sativa) varieties currently grown in Uganda mainly by smallholder farmers on small gardens (0.5 – 2ha). Due to lack of mechanized drying equipment and owing to the low volumes of their harvests, these farmers use open-sun drying methods, where the paddy is ...

  19. Improved traveling-wave efficiency in 7T human MRI using passive local loop and dipole arrays.

    Science.gov (United States)

    Yan, Xinqiang; Zhang, Xiaoliang; Gore, John C; Grissom, William A

    2017-06-01

    Traveling-wave MRI, which uses relatively small and simple RF antennae, has robust matching performance and capability for large field-of-view (FOV) imaging. However, the power efficiency of traveling-wave MRI is much lower than conventional methods, which limits its application. One simple approach to improve the power efficiency is to place passive resonators around the subject being imaged. The feasibility of this approach has been demonstrated in previous works using a single small resonant loop. In this work, we aim to explore how much the improvements can be maintained in human imaging using an array design, and whether electric dipoles can be used as local elements. First, a series of electromagnetic (EM) simulations were performed on a human model. Then RF coils were constructed and the simulation results using the best setup for head imaging were validated in MR experiments. By using the passive local loop and transverse dipole arrays, respectively, the transmit efficiency (B 1 + ) of traveling-wave MRI can be improved by 3-fold in the brain and 2-fold in the knee. The types of passive elements (loops or dipoles) should be carefully chosen for brain or knee imaging to maximize the improvement, and the enhancement depends on the local body configuration. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Stability and quench development study in small HTSC magnet

    NARCIS (Netherlands)

    Ilyin, Y.; Vysotski, V.S.; Kiss, T.; Takeo, M.; Okamoto, H.; Irie, F.

    2001-01-01

    Stability and quench development in a HTSC magnet have been experimentally studied with the transport current in the magnet being below or above the “thermal quench current” level. The magnet was tested at both cryocooler cooling and liquid nitrogen cooling, with and without background magnetic

  1. Chiral and continuum extrapolation of partially quenched lattice results

    Energy Technology Data Exchange (ETDEWEB)

    C.R. Allton; W. Armour; D.B. Leinweber; A.W. Thomas; R.D. Young

    2005-04-01

    The vector meson mass is extracted from a large sample of partially quenched, two-flavor lattice QCD simulations. For the first time, discretization, finite-volume and partial quenching artifacts are treated in a unified chiral effective field theory analysis of the lattice simulation results.

  2. intercritical heat treatments effects on low carbon steels quenched

    African Journals Online (AJOL)

    DR B. A. EZEKOYE

    Department of Physics and Astronomy, University of Nigeria, Nsukka. 2. E-mail: benjamin.ezekoye@unn.edu.ng; bezekoye@yahoo.com. ABSTRACT. Six low carbon steels containing carbon in the range 0.13-0.18wt%C were studied after intercritical quenching, intercritical quenching with low temperature tempering, ...

  3. intercritical heat treatments effects on low carbon steels quenched

    African Journals Online (AJOL)

    DR B. A. EZEKOYE

    hardening and precipitation effects [2]. Of all the metallic materials of engineering ... of this work was to investigate the effect of diverse intercritical heat treatments on the ... INTERCRITICAL HEAT TREATMENT EFFECTS ON LOW CARBON STEELS QUENCHED FROM INTERMEDIATE ... Series II- Intercritical quench with.

  4. Physical pictures of symmetry breaking in quenched QED4

    International Nuclear Information System (INIS)

    Kogut, J.B.; Argonne National Lab., IL

    1989-01-01

    We discuss 'collapse of the wavefunction' as the phenomenon underlying chiral symmetry breaking in quenched QED4. The 1/r singularity in the 'collapsed' qanti q wavefunction causes 'catalyzed symmetry breaking' which is the field theoretic analog of 'monopole induced proton decay'. The evasion of mean field exponents by the quenched theory's chiral phase transition is emphasized. (orig.)

  5. The effect of composition, electron irradiation and quenching on ...

    Indian Academy of Sciences (India)

    The ionic conductivity at room temperature exhibits a characteristic double peak for the composition = 20 and 70. Both electron beam irradiation and quenching at low temperature have resulted in an increase in conductivity by 1–2 orders of magnitude. The enhancement of conductivity upon irradiation and quenching is ...

  6. Quench-induced trapping of magnetic flux in annular

    DEFF Research Database (Denmark)

    Aaroe, M.; Monaco, R.; Rivers, R.

    2008-01-01

    The aim of the project is to investigate spontaneous symmetry breaking in non-adiabatic phase transitions (Kibble-Zurek processes). A long and narrow annular Josephson tunnel junction is subjected to repeated thermal quenches through the normal-superconducting transition. The quench rate is varied...

  7. Quench performance analysis on spare superconducting cryo-magnets

    CERN Document Server

    Warych, Agata

    2014-01-01

    The main purpose of this project was to organise and analyse the data, in particular quench performance for superconducting spare magnets considering relation of the magnets to assemblies and families. As a result of analysis an Excel file was created, which consists of quench measurements and charts for spare cryo-magnets.

  8. Effects of Various Quenching Media on the Mechanical Properties of ...

    African Journals Online (AJOL)

    The effects of quenching media used and the intercritical annealing temperatures on tensile, hardness, ductility and notch impact toughness properties are discussed. The quenching media increased the strength and hardness properties but decreased the ductility and notch impact properties of the original hot-rolled steel.

  9. Enhanced Turbulence During the Energy Quench of Disruptions

    NARCIS (Netherlands)

    Remkes, G. J. J.; Schüller, F. C.

    1991-01-01

    Enhanced electron density fluctuation levels with frequencies in the megahertz range have been observed during the energy quench phase of minor disruptions in the TORTUR Tokamak. The high frequencies of the phenomena indicate that the enhanced transport during the energy quench is caused by

  10. Evaluation of local media surveillance for improved disease recognition and monitoring in global hotspot regions.

    Directory of Open Access Journals (Sweden)

    Jessica S Schwind

    Full Text Available Digital disease detection tools are technologically sophisticated, but dependent on digital information, which for many areas suffering from high disease burdens is simply not an option. In areas where news is often reported in local media with no digital counterpart, integration of local news information with digital surveillance systems, such as HealthMap (Boston Children's Hospital, is critical. Little research has been published in regards to the specific contribution of local health-related articles to digital surveillance systems. In response, the USAID PREDICT project implemented a local media surveillance (LMS pilot study in partner countries to monitor disease events reported in print media. This research assessed the potential of LMS to enhance digital surveillance reach in five low- and middle-income countries. Over 16 weeks, select surveillance system attributes of LMS, such as simplicity, flexibility, acceptability, timeliness, and stability were evaluated to identify strengths and weaknesses in the surveillance method. Findings revealed that LMS filled gaps in digital surveillance network coverage by contributing valuable localized information on disease events to the global HealthMap database. A total of 87 health events were reported through the LMS pilot in the 16-week monitoring period, including 71 unique reports not found by the HealthMap digital detection tool. Furthermore, HealthMap identified an additional 236 health events outside of LMS. It was also observed that belief in the importance of the project and proper source selection from the participants was crucial to the success of this method. The timely identification of disease outbreaks near points of emergence and the recognition of risk factors associated with disease occurrence continue to be important components of any comprehensive surveillance system for monitoring disease activity across populations. The LMS method, with its minimal resource commitment, could

  11. Evaluation of local media surveillance for improved disease recognition and monitoring in global hotspot regions.

    Science.gov (United States)

    Schwind, Jessica S; Wolking, David J; Brownstein, John S; Mazet, Jonna A K; Smith, Woutrina A

    2014-01-01

    Digital disease detection tools are technologically sophisticated, but dependent on digital information, which for many areas suffering from high disease burdens is simply not an option. In areas where news is often reported in local media with no digital counterpart, integration of local news information with digital surveillance systems, such as HealthMap (Boston Children's Hospital), is critical. Little research has been published in regards to the specific contribution of local health-related articles to digital surveillance systems. In response, the USAID PREDICT project implemented a local media surveillance (LMS) pilot study in partner countries to monitor disease events reported in print media. This research assessed the potential of LMS to enhance digital surveillance reach in five low- and middle-income countries. Over 16 weeks, select surveillance system attributes of LMS, such as simplicity, flexibility, acceptability, timeliness, and stability were evaluated to identify strengths and weaknesses in the surveillance method. Findings revealed that LMS filled gaps in digital surveillance network coverage by contributing valuable localized information on disease events to the global HealthMap database. A total of 87 health events were reported through the LMS pilot in the 16-week monitoring period, including 71 unique reports not found by the HealthMap digital detection tool. Furthermore, HealthMap identified an additional 236 health events outside of LMS. It was also observed that belief in the importance of the project and proper source selection from the participants was crucial to the success of this method. The timely identification of disease outbreaks near points of emergence and the recognition of risk factors associated with disease occurrence continue to be important components of any comprehensive surveillance system for monitoring disease activity across populations. The LMS method, with its minimal resource commitment, could be one tool used to

  12. HST-WFC3 Near-Infrared Spectroscopy of Quenched Galaxies at zeta approx 1.5 from the WISP Survey: Stellar Populations Properties

    Science.gov (United States)

    Bedregal, A. G.; Scarlata, C.; Henry, A. L.; Atek, H.; Rafelski, M.; Teplitz, H. I.; Dominguez, A.; Siana, B.; Colbert, J. W.; Malkan, M.; hide

    2013-01-01

    We combine Hubble Space Telescope (HST) G102 and G141 near-IR (NIR) grism spectroscopy with HST/WFC3- UVIS, HST/WFC3-IR, and Spitzer/IRAC [3.6 microns] photometry to assemble a sample of massive (log(Mstar/M solar mass) at approx 11.0) and quenched (specific star formation rate spectroscopy for quenched sources at these redshifts. In contrast to the local universe, zeta approx 1.5 quenched galaxies in the high-mass range have a wide range of stellar population properties. We find that their spectral energy distributions (SEDs) are well fitted with exponentially decreasing star formation histories and short star formation timescales (tau less than or equal to 100 M/yr). Quenched galaxies also show a wide distribution in ages, between 1 and 4 G/yr. In the (u - r)0-versus-mass space quenched galaxies have a large spread in rest-frame color at a given mass. Most quenched galaxies populate the zeta appro. 1.5 red sequence (RS), but an important fraction of them (32%) have substantially bluer colors. Although with a large spread, we find that the quenched galaxies on the RS have older median ages (3.1 G/yr) than the quenched galaxies off the RS (1.5 G/yr). We also show that a rejuvenated SED cannot reproduce the observed stacked spectra of (the bluer) quenched galaxies off the RS. We derive the upper limit on the fraction of massive galaxies on the RS at zeta approx 1.5 to be 2 and the zeta approx 1.5 RS. According to their estimated ages, the time required for quenched galaxies off the RS to join their counterparts on the z approx. 1.5 RS is of the order of approx. 1G/yr.

  13. Envelope-based inter-aural time difference localization training to improve speech-in-noise perception in the elderly.

    Science.gov (United States)

    Delphi, Maryam; Lotfi, Yones; Moossavi, Abdollah; Bakhshi, Enayatollah; Banimostafa, Maryam

    2017-01-01

    Background: Many elderly individuals complain of difficulty in understanding speech in noise despite having normal hearing thresholds. According to previous studies, auditory training leads to improvement in speech-in-noise perception, but these studies did not consider the etiology, so their results cannot be generalized. The present study aimed at investigating the effectiveness of envelopebased interaural time difference (ITD ENV) localization training on improving ITD threshold and speech-in-noise perception. Methods: Thirty-two elderly males aged 55 to 65 years with clinically diagnosed normal hearing at 250-2000 Hertz, who suffered from speech-in-noise perception difficulty participated in this study. These individuals were randomly divided into training and control groups: 16 elderlies in the experimental group received envelope-based interaural time difference localization training in 9 sessions, but 16 matched elderlies in the control group did not receive any training. The ITD ENV threshold and spatial word recognition score (WRS) in noise were analyzed before and after the localization training. Results: Findings demonstrated that following the training program, the interaural time difference envelope threshold and spatial word recognition score (WRS) in noise were improved significantly in the experimental group (p≤ 0.001). Moreover, a significant difference was detected in interaural time difference envelope threshold and spatial word recognition score (WRS) in noise (p≤ 0.001) before and after the training in the experimental group. Conclusion: The results of the present study revealed the effectiveness of envelope- based interaural time difference localization training in localization ability and speech in noise perception in the elderlies with normal hearing up to 2000 Hz who suffered from speech-in-noise perception difficulty.

  14. Malignant melanoma and radiotherapy: Past myths, excellent local control in 146 studied lesions at Georgetown University, and improving future management

    Directory of Open Access Journals (Sweden)

    Pooya eJahanshahi

    2012-11-01

    Full Text Available Introduction: Once thought to be radioresistant, emerging cellular and clinical evidence now suggests melanoma can respond to large radiation doses per fraction.Materials and Methods: We conducted a retrospective study of all patients treated with stereotactic radiosurgery and stereotactic body radiotherapy at Georgetown University Hospital from May 2002 through November 2008 and studied the classic Extrapolated Total Dose Corrected for Volume (ETDvol model for predicting melanoma tumor response. Region-specific tumor outcomes were categorized by RECIST criteria and local control curves were estimated and analyzed when stratified by ETDvol thresholds by use of the Kaplan-Meier method.Results: Follow-up information was available for 78 lesions (49 intracranial, 8 spinal, and 21 body with mean follow-up period of 9.2 (range, 2-36 months. 1-year local control rates for intracranial, spinal, and body tumors were 84%, 100%, and 72% respectively. Treatments in general were well-tolerated. Increased ETDvol (p<0.001 among intracranial sites resulted from larger (p<0.001 doses per fraction combined with smaller (p<0.001 tumor diameters. Intracranial 6-, 12-, and 24-month local control rates when treated above ETDvol threshold of 230 Gy were all 90% vs. 89%, 80%, and 53% below this threshold. Body 6- and 12-month local control rates when treated above ETDvol threshold of 100 Gy were 100% and 80% vs. 74% and 59% below this threshold. Discussion: By tailoring to melanoma’s unique radiobiology with large radiation doses per fraction, favorable local control was safely achieved. The ETDvol model combines the important factor of dose per fraction in melanoma treatment with a volume correction factor to predict tumor response. Although limited sample size may have prevented reaching statistical significance for local control improvements using ETDvol thresholds, optimal thresholds may exist to improve future tumor responses and further research is required.

  15. Smooth and fast versus instantaneous quenches in quantum field theory

    International Nuclear Information System (INIS)

    Das, Sumit R.; Galante, Damián A.; Myers, Robert C.

    2015-01-01

    We examine in detail the relationship between smooth fast quantum quenches, characterized by a time scale δt, and instantaneous quenches, within the framework of exactly solvable mass quenches in free scalar field theory. Our earlier studies http://dx.doi.org/10.1103/PhysRevLett.112.171601 and http://dx.doi.org/10.1007/JHEP02(2015)167 highlighted that the two protocols remain distinct in the limit δt→0 because of the relation of the quench rate to the UV cut-off, i.e., 1/δt≪Λ always holds in the fast smooth quenches while 1/δt∼Λ for instantaneous quenches. Here we study UV finite quantities like correlators at finite spatial distances and the excess energy produced above the final ground state energy. We show that at late times and large distances (compared to the quench time scale) the smooth quench correlator approaches that for the instantaneous quench. At early times, we find that for small spatial separation and small δt, the correlator scales universally with δt, exactly as in the scaling of renormalized one point functions found in earlier work. At larger separation, the dependence on δt drops out. The excess energy density is finite (for finite mδt) and scales in a universal fashion for all d. However, the scaling behaviour produces a divergent result in the limit mδt→0 for d≥4, just as in an instantaneous quench, where it is UV divergent for d≥4. We argue that similar results hold for arbitrary interacting theories: the excess energy density produced is expected to diverge for scaling dimensions Δ>d/2.

  16. Smooth and fast versus instantaneous quenches in quantum field theory

    Energy Technology Data Exchange (ETDEWEB)

    Das, Sumit R. [Department of Physics and Astronomy, University of Kentucky,505 Rose St, Lexington, KY 40506 (United States); Galante, Damián A. [Department of Applied Mathematics, University of Western Ontario,1151 Richmond Street, London, ON N6A 5B7 (Canada); Perimeter Institute for Theoretical Physics,55 Caroline St N, Waterloo, ON N2L 2Y5 (Canada); Kavli Institute for Theoretical Physics, University of California,Kohn Hall, Santa Barbara, CA 93106 (United States); Myers, Robert C. [Perimeter Institute for Theoretical Physics,55 Caroline St N, Waterloo, ON N2L 2Y5 (Canada)

    2015-08-17

    We examine in detail the relationship between smooth fast quantum quenches, characterized by a time scale δt, and instantaneous quenches, within the framework of exactly solvable mass quenches in free scalar field theory. Our earlier studies http://dx.doi.org/10.1103/PhysRevLett.112.171601 and http://dx.doi.org/10.1007/JHEP02(2015)167 highlighted that the two protocols remain distinct in the limit δt→0 because of the relation of the quench rate to the UV cut-off, i.e., 1/δt≪Λ always holds in the fast smooth quenches while 1/δt∼Λ for instantaneous quenches. Here we study UV finite quantities like correlators at finite spatial distances and the excess energy produced above the final ground state energy. We show that at late times and large distances (compared to the quench time scale) the smooth quench correlator approaches that for the instantaneous quench. At early times, we find that for small spatial separation and small δt, the correlator scales universally with δt, exactly as in the scaling of renormalized one point functions found in earlier work. At larger separation, the dependence on δt drops out. The excess energy density is finite (for finite mδt) and scales in a universal fashion for all d. However, the scaling behaviour produces a divergent result in the limit mδt→0 for d≥4, just as in an instantaneous quench, where it is UV divergent for d≥4. We argue that similar results hold for arbitrary interacting theories: the excess energy density produced is expected to diverge for scaling dimensions Δ>d/2.

  17. Does social insurance enrollment improve citizen assessment of local government performance? Evidence from China.

    Science.gov (United States)

    Huang, Xian; Gao, Qin

    2018-02-01

    Although many studies claim that social policies are "carrots" that authoritarian leaders use to garner public support, the assumption that social benefits can boost public support of government has been rarely tested empirically, especially at the local levels. This article investigates the effects of social insurance enrollment on citizens' assessment of local government performance using data from the 2010 China Family Panel Study. We use propensity score matching to reduce selection bias and ordered probit regressions with fixed effects to examine these possible effects. We find that social insurance enrollment had a significant positive effect on rural citizens' assessment of government performance, but this effect did not exist for their urban and migrant peers. This discrepancy could be largely due to the groups' different expectations for government redistribution and their distinct experiences of China's social welfare reform. We conclude that the Chinese authoritarian government has achieved partial success in its attempt to use social policies to maintain popular support. Published by Elsevier Inc.

  18. Improved radioimaging and tumor localization with monoclonal F(ab')2

    International Nuclear Information System (INIS)

    Wahl, R.L.; Parker, C.W.; Philpott, G.W.

    1983-01-01

    Monoclonal anti-tumor antibodies have great promise for radioimmunodetection and localization of tumors. Fab and F(ab')2 fragments, which lack the Fc fragment of antibody (Ab), are cleared more rapidly from the circulation and may have less nonspecific tissue binding than intact Ab. In radioimaging studies using a murine monoclonal antibody to carcinoembryonic antigen in a human colon carcinoma xenografted into hamsters, F(ab')2 fragments were shown superior to Fab fragments and intact antibody for scintiscanning. In double-label experiments with anti-CEA antibody and control monoclonal IgG, F(ab')2 fragments were found to give better and more rapid specific tumor localization than intact antibody or Fab fragments. F(ab')2 fragments offer significant promise for tumor imaging and possibly therapy

  19. Fault feature extraction method based on local mean decomposition Shannon entropy and improved kernel principal component analysis model

    Directory of Open Access Journals (Sweden)

    Jinlu Sheng

    2016-07-01

    Full Text Available To effectively extract the typical features of the bearing, a new method that related the local mean decomposition Shannon entropy and improved kernel principal component analysis model was proposed. First, the features are extracted by time–frequency domain method, local mean decomposition, and using the Shannon entropy to process the original separated product functions, so as to get the original features. However, the features been extracted still contain superfluous information; the nonlinear multi-features process technique, kernel principal component analysis, is introduced to fuse the characters. The kernel principal component analysis is improved by the weight factor. The extracted characteristic features were inputted in the Morlet wavelet kernel support vector machine to get the bearing running state classification model, bearing running state was thereby identified. Cases of test and actual were analyzed.

  20. Integrating watershed hydrology and economics to establish a local market for water quality improvement: A field experiment.

    Science.gov (United States)

    Uchida, Emi; Swallow, Stephen K; Gold, Arthur; Opaluch, James; Kafle, Achyut; Merrill, Nathaniel; Michaud, Clayton; Gill, Carrie Anne

    2018-04-01

    Innovative market mechanisms are being increasingly recognized as effective decision-making institutions to incorporate the value of ecosystem services into the economy. We present a field experiment that integrates an economic auction and a biophysical water flux model to develop a local market process consisting of both the supply and demand sides. On the supply side, we operate an auction with small-scale livestock owners who bid for contracts to implement site-specific manure management practices that reduce phosphorus loadings to a major reservoir. On the demand side, we implement a real money, multi-unit public good auction for these contracts with residents who potentially benefit from reduced water quality risks. The experiments allow us to construct supply and demand curves to find an equilibrium price for water quality improvement. The field experiments provide a proof-of-concept for practical implementation of a local market for environmental improvements, even for the challenging context of nonpoint pollution.

  1. Communicative Interaction among Local Editorial Staff Members: Current Situation and the Ways of its Improving

    Directory of Open Access Journals (Sweden)

    Mariya V. Korotitskaya

    2017-06-01

    Full Text Available Communication between management and employees is very important in organizations. However, communication problems might be more felt in any media organization as a whole and in the local media staff in particular. It’s obvious that news workers have everyday communicative interaction with different newsmakers. The article deals with the study and analysis of the communicative interaction between the local editorial creative staff members. Internal and external organizational understanding data are considered. It is determined that the level of organizational communication development influences the local editorial success and employees’ performance. Mutual understanding as the basic criterion of effective communication has several forms. The subject of our study is organizational understanding, that is, a special type of editorial staff relationship which is limited by the boundaries of the organization and is essential for its successful functioning and development. The analysis of empirical data allowed to identify the main problematic aspects and to work out the recommendations for vertical and horizontal communication development.

  2. Irregular Winding of Pre-preg Fibres Aimed at the Local Improvement of Flexural Properties

    Directory of Open Access Journals (Sweden)

    Petr Kulhavy

    2017-12-01

    Full Text Available The main undisputed benefit of using long fibre composite materials, whose properties could be targeted for a particular application, lies in the efficient utilisation of material. Using a method of pre-impregnated fibre winding, a rod with a reinforced middle part was created through the local adjustment of the winding angle in order to increase the local bending stiffness. The aim of our work was to describe, experimentally and subsequently using appropriate numerical models, the behaviour of two composite rods, one with a locally variable winding angle and the other with a constant winding angle. The difference in the mechanical behaviour of both structures was clearly evident during the experiment. By using a suitable composite pre-processor and by choosing some multiple element sets, it was also possible to accurately simulate the real behaviour of such components, which actually have several regions, each with different mechanical parameters. Together with the expected different flexural strength, a traditional three-point bending test also explored the different shape of the resulting deformation in the two compared parts. Differences in the maximum strength and the mode of fi nal deformations were also identified.

  3. Slow fashion and sustainability in Spain: How can local manufacturing improve sustainability and how do consumers respond?

    OpenAIRE

    Karaosman, Hakan; Morales Alonso, Gustavo; Brun, Alessandro

    2014-01-01

    "Slow Fashion" attempts to offset the demand for fast fashion and mass production (Fletcher, 2007). Consumers' response to sustainability-based practices is a limited discourse and studies for slow fashion concept are scarce. This study thus aims to enlighten the subject of how slow fashion concept could improve local economies and how Spanish consumers respond to such initiatives. This paper is based on an exploratory qualitative research for which focus group interviews including three grou...

  4. Improved Models for Prediction of Locally Intense Aeroacoustic Loads and Vibration Environments, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — ATA Engineering, Inc. proposes an STTR program to develop innovative tools and methods that will significantly improve the accuracy of random vibration response...

  5. Improving the Classification Accuracy for Near-Infrared Spectroscopy of Chinese Salvia miltiorrhiza Using Local Variable Selection

    Directory of Open Access Journals (Sweden)

    Lianqing Zhu

    2018-01-01

    Full Text Available In order to improve the classification accuracy of Chinese Salvia miltiorrhiza using near-infrared spectroscopy, a novel local variable selection strategy is thus proposed. Combining the strengths of the local algorithm and interval partial least squares, the spectra data have firstly been divided into several pairs of classes in sample direction and equidistant subintervals in variable direction. Then, a local classification model has been built, and the most proper spectral region has been selected based on the new evaluation criterion considering both classification error rate and best predictive ability under the leave-one-out cross validation scheme for each pair of classes. Finally, each observation can be assigned to belong to the class according to the statistical analysis of classification results of the local classification model built on selected variables. The performance of the proposed method was demonstrated through near-infrared spectra of cultivated or wild Salvia miltiorrhiza, which are collected from 8 geographical origins in 5 provinces of China. For comparison, soft independent modelling of class analogy and partial least squares discriminant analysis methods are, respectively, employed as the classification model. Experimental results showed that classification performance of the classification model with local variable selection was obvious better than that without variable selection.

  6. iROLL: does 3-D radioguided occult lesion localization improve surgical management in early-stage breast cancer?

    Energy Technology Data Exchange (ETDEWEB)

    Bluemel, Christina; Kajdi, Georg W.; Schmid, Jan; Buck, Andreas K.; Herrmann, Ken [University Hospital of Wuerzburg, Department of Nuclear Medicine, Wuerzburg (Germany); Cramer, Andreas; Grossmann, Christoph; Grimminger, Hanns-Joerg [Missionsaerztliches Klinikum Wuerzburg, Department of Obstetrics and Gynecology, Wuerzburg (Germany); Malzahn, Uwe [University of Wuerzburg, Institute of Clinical Epidemiology and Biometry, Wuerzburg (Germany); Lamp, Nora [University of Wuerzburg, Institute of Pathology, Wuerzburg (Germany); Langen, Heinz-Jakob [Missionsaerztliches Klinikum Wuerzburg, Department of Radiology, Wuerzburg (Germany)

    2015-10-15

    To prospectively evaluate the feasibility of 3-D radioguided occult lesion localization (iROLL) and to compare iROLL with wire-guided localization (WGL) in patients with early-stage breast cancer undergoing breast-conserving surgery and sentinel lymph node biopsy (SLNB). WGL (standard procedure) and iROLL in combination with SLNB were performed in 31 women (mean age 65.1 ± 11.2 years) with early-stage breast cancer and clinically negative axillae. Patient comfort in respect of both methods was assessed using a ten point scale. SLNB and iROLL were guided by freehand SPECT (fhSPECT). The results of the novel 3-D image-based method were compared with those of WGL, ultrasound-based lesion localization, and histopathology. iROLL successfully detected the malignant primary and at least one sentinel lymph node in 97 % of patients. In a single patient (3 %), only iROLL, and not WGL, enabled lesion localization. The variability between fhSPECT and ultrasound-based depth localization of breast lesions was low (1.2 ± 1.4 mm). Clear margins were achieved in 81 % of the patients; however, precise prediction of clear histopathological surgical margins was not feasible using iROLL. Patients rated iROLL as less painful than WGL with a pain score 0.8 ± 1.2 points (p < 0.01) lower than the score for iROLL. iROLL is a well-tolerated and feasible technique for localizing early-stage breast cancer in the course of breast-conserving surgery, and is a suitable replacement for WGL. As a single image-based procedure for localization of breast lesions and sentinel nodes, iROLL may improve the entire surgical procedure. However, no advantages of the image-guided procedure were found with regard to prediction of complete tumour resection. (orig.)

  7. Quenching of weak interactions in nucleon matter

    International Nuclear Information System (INIS)

    Cowell, S.; Pandharipande, V.R.

    2003-01-01

    We have calculated the one-body Fermi and Gamow-Teller charge-current and vector and axial-vector neutral-current nuclear matrix elements in nucleon matter at densities of 0.08, 0.16, and 0.24 fm -3 and proton fractions ranging from 0.2 to 0.5. The correlated states for nucleon matter are obtained by operating on Fermi-gas states by a symmetrized product of pair correlation operators determined from variational calculations with the Argonne-v18 and Urbana-IX two- and three-nucleon interactions. The squares of the charge- current matrix elements are found to be quenched by 20-25 % by the short-range correlations in nucleon matter. Most of the quenching is due to spin-isospin correlations induced by the pion exchange interactions which change the isospins and spins of the nucleons. A large part of it can be related to the probability for a spin-up proton quasiparticle to be a bare spin-up/down proton/neutron. Within the interval considered, the charge-current matrix elements do not have significant dependence on the matter density, proton fraction, and magnitudes of nucleon momenta; however, they do depend on momentum transfer. The neutral-current matrix elements have a significant dependence on the proton fraction. We also calculate the matrix elements of the nuclear Hamiltonian in the same correlated basis. These provide relatively mild effective interactions that give the variational energies in the Hartree-Fock approximation. The calculated two-nucleon effective interaction describes the spin-isospin susceptibilities of nuclear and neutron matter fairly accurately. However terms greater than or equal to three-body terms are necessary to reproduce the compressibility. Realistic calculations of weak interaction rates in nucleon matter can presumably be carried out using the effective operators and interactions studied here. All presented results use the simple two-body cluster approximation to calculate the correlated basis matrix elements. This allows for a clear

  8. Star Formation Quenching in Quasar Host Galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Carniani, Stefano, E-mail: sc888@mrao.cam.ac.uk [Cavendish Laboratory, University of Cambridge, Cambridge (United Kingdom); Kavli Institute for Cosmology, University of Cambridge, Cambridge (United Kingdom)

    2017-10-16

    Galaxy evolution is likely to be shaped by negative feedback from active galactic nuclei (AGN). In the whole range of redshifts and luminosities studied so far, galaxies hosting an AGN frequently show fast and extended outflows consisting in both ionized and molecular gas. Such outflows could potentially quench the start formation within the host galaxy, but a clear evidence of negative feedback in action is still missing. Hereby I will analyse integral-field spectroscopic data for six quasars at z ~ 2.4 obtained with SINFONI in the H- and K-band. All the quasars show [Oiii]λ5007 line detection of fast, extended outflows. Also, the high signal-to-noise SINFONI observations allow the identification of faint narrow Hα emission (FWHM < 500 km/s), which is spatially extended and associated with star formation in the host galaxy. On paper fast outflows are spatially anti-correlated with star-formation powered emission, i.e., star formation is suppressed in the area affected by the outflow. Nonetheless as narrow, spatially-extended Hα emission, indicating star formation rates of at least 50–100 M{sub ⊙} yr{sup −1}, has been detected, either AGN feedback is not affecting the whole host galaxy, or star formation is completely quenched only by several feedback episodes. On the other hand, a positive feedback scenario, supported by narrow emission in Hα extending along the edges of the outflow cone, suggests that galaxy-wide outflows could also have a twofold role in the evolution of the host galaxy. Finally, I will present CO(3-2) ALMA data for three out of the six QSOs observed with SINFONI. Flux maps obtained for the CO(3-2) transition suggest that molecular gas within the host galaxy is swept away by fast winds. A negative-feedback scenario is supported by the inferred molecular gas mass in all three objects, which is significantly below what observed in non-active main-sequence galaxies at high-z.

  9. Witnessing The Onset Of Environmental Quenching At Z 1-2

    Science.gov (United States)

    Fossati, Matteo

    2017-06-01

    During the last decade observations of galaxies across cosmic times coupled with cosmological simulations have provided an increasingly clear description of galaxy evolution. In particular we have a fairly detailed phenomenological picture of how galaxies transition from star forming to passive (or quenched) as a function of their internal properties (e.g. stellar mass) and the external environment (e.g. local density). By exploiting the highly complete coverage of grism and spectroscopic redshifts from the 3D-HST survey, we derive the local environment for a deep and complete sample of galaxies in the five 3D-HST deep fields at 0.5 definition of environment also requires accurate calibrations obtained using the most up to date semi-analytic model derived from the Millennium simulation. By combining observational data and models we have devised a robust statistical framework within which we link observables to physical quantities (e.g. halo mass and central/satellite status). In this talk I will present our latest results on the environmental quenching of satellites up to z 2.5 in the range of haloes commonly included in our sample Mhalo 1 this timescale approaches the Hubble time. I will discuss the physical motivation of these results in terms of quenching mechanisms and gas content of the satellites at the epoch of infall.

  10. Does ultrasound-guided lidocaine injection improve local anaesthesia before femoral artery catheterization?

    Energy Technology Data Exchange (ETDEWEB)

    Spiliopoulos, S., E-mail: stavspiliop@upatras.g [Department of Diagnostic and Interventional Radiology, Patras University Hospital, School of Medicine, Patras (Greece); Katsanos, K.; Diamantopoulos, A.; Karnabatidis, D.; Siablis, D. [Department of Diagnostic and Interventional Radiology, Patras University Hospital, School of Medicine, Patras (Greece)

    2011-05-15

    Aim: To present the results of a prospective, randomized, single-centre study investigating local anaesthesia before percutaneous common femoral artery (CFA) puncture and catheterization with the use of ultrasound-guided injection of lidocaine versus standard infiltration by manual palpation. Materials and methods: Patients scheduled to undergo diagnostic or therapeutic transfemoral catheter-based procedures gave informed consent and were randomized in two groups. In the first arm local anaesthesia with lidocaine hydrochloride 1% was performed under ultrasound guidance (group U/S), while in the second arm the standard method of manual artery palpation was applied (group M). In both groups, subsequent CFA catheterization was achieved under ultrasound guidance. The primary study endpoint was peri-procedural pain level evaluated with a visual-analogue scale (VAS score 0-10). Results: Between January 2009 and 2010, 200 patients (161 men, mean age 63 {+-} 12 years) were equally assigned to each group without any significant differences in baseline demographics. Patients in group U/S experienced significantly less pain during CFA catheterization in comparison with group M with a difference of three points in mean VAS score reported (1.6 {+-} 1.6 versus 4.6 {+-} 1.9, p < 0.0001). In addition, significantly less volume of lidocaine was used in group U/S compared to group M (16 {+-} 2.7 versus 19 {+-} 0.8 ml, p < 0.001).Total vascular access time was similar in both groups (4.4 {+-} 1.3 versus 4.5 {+-} 1.3 min). Overall complications included two small groin haematomas in each group. Conclusion: Ultrasound-guided local anaesthesia of the CFA prior to percutaneous transcatheter procedures is safe and achieves superior levels of analgesia with minimal patient pain and discomfort compared to the standard method of manual palpation.

  11. Improved iris localization by using wide and narrow field of view cameras for iris recognition

    Science.gov (United States)

    Kim, Yeong Gon; Shin, Kwang Yong; Park, Kang Ryoung

    2013-10-01

    Biometrics is a method of identifying individuals by their physiological or behavioral characteristics. Among other biometric identifiers, iris recognition has been widely used for various applications that require a high level of security. When a conventional iris recognition camera is used, the size and position of the iris region in a captured image vary according to the X, Y positions of a user's eye and the Z distance between a user and the camera. Therefore, the searching area of the iris detection algorithm is increased, which can inevitably decrease both the detection speed and accuracy. To solve these problems, we propose a new method of iris localization that uses wide field of view (WFOV) and narrow field of view (NFOV) cameras. Our study is new as compared to previous studies in the following four ways. First, the device used in our research acquires three images, one each of the face and both irises, using one WFOV and two NFOV cameras simultaneously. The relation between the WFOV and NFOV cameras is determined by simple geometric transformation without complex calibration. Second, the Z distance (between a user's eye and the iris camera) is estimated based on the iris size in the WFOV image and anthropometric data of the size of the human iris. Third, the accuracy of the geometric transformation between the WFOV and NFOV cameras is enhanced by using multiple matrices of the transformation according to the Z distance. Fourth, the searching region for iris localization in the NFOV image is significantly reduced based on the detected iris region in the WFOV image and the matrix of geometric transformation corresponding to the estimated Z distance. Experimental results showed that the performance of the proposed iris localization method is better than that of conventional methods in terms of accuracy and processing time.

  12. Does ultrasound-guided lidocaine injection improve local anaesthesia before femoral artery catheterization?

    International Nuclear Information System (INIS)

    Spiliopoulos, S.; Katsanos, K.; Diamantopoulos, A.; Karnabatidis, D.; Siablis, D.

    2011-01-01

    Aim: To present the results of a prospective, randomized, single-centre study investigating local anaesthesia before percutaneous common femoral artery (CFA) puncture and catheterization with the use of ultrasound-guided injection of lidocaine versus standard infiltration by manual palpation. Materials and methods: Patients scheduled to undergo diagnostic or therapeutic transfemoral catheter-based procedures gave informed consent and were randomized in two groups. In the first arm local anaesthesia with lidocaine hydrochloride 1% was performed under ultrasound guidance (group U/S), while in the second arm the standard method of manual artery palpation was applied (group M). In both groups, subsequent CFA catheterization was achieved under ultrasound guidance. The primary study endpoint was peri-procedural pain level evaluated with a visual-analogue scale (VAS score 0-10). Results: Between January 2009 and 2010, 200 patients (161 men, mean age 63 ± 12 years) were equally assigned to each group without any significant differences in baseline demographics. Patients in group U/S experienced significantly less pain during CFA catheterization in comparison with group M with a difference of three points in mean VAS score reported (1.6 ± 1.6 versus 4.6 ± 1.9, p < 0.0001). In addition, significantly less volume of lidocaine was used in group U/S compared to group M (16 ± 2.7 versus 19 ± 0.8 ml, p < 0.001).Total vascular access time was similar in both groups (4.4 ± 1.3 versus 4.5 ± 1.3 min). Overall complications included two small groin haematomas in each group. Conclusion: Ultrasound-guided local anaesthesia of the CFA prior to percutaneous transcatheter procedures is safe and achieves superior levels of analgesia with minimal patient pain and discomfort compared to the standard method of manual palpation.

  13. Catalysts and barriers: Improving quality of contact between expatriates and their local host

    DEFF Research Database (Denmark)

    van Bakel, Marian; van Oudenhoven, Jan Pieter; Gerritsen, Marinel

    2014-01-01

    , timing, communication breakdown, and cultural differences) to the contact were identified. Key factors were similarities, motivation and benefits, because they made it possible to overcome some of the barriers. The study discusses the implications of these findings and provides recommendations......-three expatriates and ten partners were put in touch with a local host, with whom they undertook all kinds of activities together during a period of nine months. Five catalysts (similarities, motivation, benefits, proximity, and research context) and seven barriers (anxiety, different expectations, busy schedules...

  14. Japanese Forwarders’ Local Import Hub in Asia: 3PL Power and Environmental Improvement

    Directory of Open Access Journals (Sweden)

    Kunio MIYASHITA

    2015-09-01

    Full Text Available The purpose of this paper is to demonstrate by an econometric method which countries or regions in Asia are superior import hubs for Japan based on two axes, the third party logistics (3PL business power of Japanese local forwarders and the logistical environment catch-up speed of these countries. According to the estimated results, this simple model can explain the structural changes in China's logistics based on its WTO accession and can develop Japanese forwarders’ stable import hub ranking by suggesting total optimization in the East Asian NIES (newly industrial economies and the ASEAN (Association of Southeast Asian Countries districts by Japanese forwarders.

  15. An Improved Analytical Model of the Local Interstellar Magnetic Field: The Extension to Compressibility

    Energy Technology Data Exchange (ETDEWEB)

    Kleimann, Jens; Fichtner, Horst [Ruhr-Universität Bochum, Fakultät für Physik und Astronomie, Institut für Theoretische Physik IV, Bochum (Germany); Röken, Christian, E-mail: jk@tp4.rub.de, E-mail: hf@tp4.rub.de, E-mail: christian.roeken@mathematik.uni-regensburg.de [Universität Regensburg, Fakultät für Mathematik, Regensburg (Germany)

    2017-03-20

    A previously published analytical magnetohydrodynamic model for the local interstellar magnetic field in the vicinity of the heliopause (Röken et al. 2015) is extended from incompressible to compressible, yet predominantly subsonic flow, considering both isothermal and adiabatic equations of state. Exact expressions and suitable approximations for the density and the flow velocity are derived and discussed. In addition to the stationary induction equation, these expressions also satisfy the momentum balance equation along stream lines. The practical usefulness of the corresponding, still exact, analytical magnetic field solution is assessed by comparing it quantitatively to results from a fully self-consistent magnetohydrodynamic simulation of the interstellar magnetic field draping around the heliopause.

  16. Quench Protection and Magnet Powe Supply Requirements for the MICE Focusing and Coupling Magnets

    International Nuclear Information System (INIS)

    Green, Michael A.; Witte, Holger

    2005-01-01

    This report discusses the quench protection and power supply requirements of the MICE superconducting magnets. A section of the report discusses the quench process and how to calculate the peak voltages and hotspot temperature that result from a magnet quench. A section of the report discusses conventional quench protection methods. Thermal quench back from the magnet mandrel is also discussed. Selected quench protection methods that result in safe quenching of the MICE focusing and coupling magnets are discussed. The coupling of the MICE magnets with the other magnets in the MICE is described. The consequences of this coupling on magnet charging and quenching are discussed. Calculations of the quenching of a magnet due quench back from circulating currents induced in the magnet mandrel due to quenching of an adjacent magnet are discussed. The conclusion of this report describes how the MICE magnet channel will react when one or magnets in that channel are quenched

  17. Exploring how to improve patients' experience in hospital at both national and local levels.

    Science.gov (United States)

    Cornwell, Jocelyn

    At The King's Fund's Point of Care programme, we wanted to discover which types of intervention were most likely to achieve positive results and why. Where should staff and hospital senior leaders with an interest in improving patients' experience focus their effort? Should it be on the front line, with staff in direct contact with patients? On the board, with the non-executive and executive directors? Or in the middle, with matrons and business managers? Who is best placed to lead the improvement efforts and what support do these people need in order to be effective? Before we could answer these questions, we needed to frame the factors that shaped patients' experience in hospital and to review the lessons learnt from the limited research available on interventions designed to improve patients' experiences.

  18. Quasiparticle explanation of ``weak thermalization'' regime under quench in a non-integrable quantum spin chain

    Science.gov (United States)

    Lin, Cheng-Ju; Motrunich, Olexei

    Eigenstate Thermalization Hypothesis provides one picture of thermalization in a quantum system by looking at individual eigenstates. However, it is also important to consider how local observables reach equilibrium values dynamically. Quench protocol is one of the settings to study such questions. A recent numerical study [Banuls, Cirac, and Hastings, Phys. Rev. Lett. 106, 050405 (2011)] of a nonintegrable quantum Ising model with longitudinal field under such quench setting found different behaviors under different initial quantum states. One particular case termed ``weak thermalization'' regime showed apparently persistent oscillations of some observables. Here we provide an explanation of such oscillations. We use perturbation theory near the ground state of the model, and identify the oscillation frequency as the quasiparticle mass. With this quasiparticle picture, we can then address the long-time behavior of the oscillations.

  19. Minimum film-boiling quench temperature increase by CuO porous-microstructure coating

    Science.gov (United States)

    Kang, Jun-young; Lee, Gi Cheol; Kaviany, Massoud; Park, Hyun Sun; Moriyama, Kiyofumi; Kim, Moo Hwan

    2017-01-01

    Increase in the minimum film-boiling quench temperature, TMFB, is achieved with microstructured CuO particles, and attributed to local cooling (fin effect) by the microstructure causing liquid-solid contact. A periodic structure is obtained using electrochemical deposition of 1 μm diameter particles on brass sphere diameter 15 mm forming unit-cell porous cones of average height L = 100 μm and base diameter D = 20 μm. Fin analysis predicts the cone tip cooling to the homogeneous nucleation temperature of water (˜330 °C), while the base temperature is at 600 °C. This causes liquid-solid contact during quenching, and analysis suggests the fin effective thermal conductivity ⟨k⟩ and fin characteristic length L2/D are key to this liquid-solid contact that influences TMFB.

  20. Quench-induced resonant tunneling mechanisms of bosons in an optical lattice with harmonic confinement

    Science.gov (United States)

    Mistakidis, Simeon; Koutentakis, Georgios; Schmelcher, Peter; Theory Group of Fundamental Processes in Quantum Physics Team

    2017-04-01

    The non-equilibrium dynamics of small boson ensembles in one-dimensional optical lattices is explored upon a sudden quench of an additional harmonic trap from strong to weak confinement. We find that the competition between the initial localization and the repulsive interaction leads to a resonant response of the system for intermediate quench amplitudes, corresponding to avoided crossings in the many-body eigenspectrum with varying final trap frequency. In particular, we show that these avoided crossings can be utilized to prepare the system in a desired state. The dynamical response is shown to depend on both the interaction strength as well as the number of atoms manifesting the many-body nature of the tunneling dynamics. Deutsche Forschungsgemeinschaft (DFG) in the framework of the SFB 925 ``Light induced dynamics and control of correlated quantum systems''.

  1. Quench Property of Twisted-Pair MgB$_2$ Superconducting Cables in Helium Gas

    CERN Document Server

    Spurrell, J; Falorio, I; Pelegrin, J; Ballarino, A; Yang, Y

    2015-01-01

    CERN's twisted-pair superconducting cable is a novel design which offers filament transposition, low cable inductance and is particularly suited for tape conductors such as 2G YBCO coated conductors, Ag-sheathed Bi2223 tapes and Ni/Monel-sheathed MgB2 tapes. A typical design of such twistedpair cables consists of multiple superconducting tapes intercalated with thin copper tapes as additional stabilizers. The copper tapes are typically not soldered to the superconducting tapes so that sufficient flexibility is retained for the twisting of the tape assembly. The electrical and thermal contacts between the copper and superconducting tapes are an important parameter for current sharing, cryogenic stability and quench propagation. Using an MgB2 twisted-pair cable assembly manufactured at CERN, we have carried out minimum quench energy (MQE) and propagation velocity (vp) measurements with point-like heat deposition localized within a tape. Furthermore, different contacts between the copper and superconductor aroun...

  2. Crossover physics in the nonequilibrium dynamics of quenched quantum impurity systems.

    Science.gov (United States)

    Vasseur, Romain; Trinh, Kien; Haas, Stephan; Saleur, Hubert

    2013-06-14

    A general framework is proposed to tackle analytically local quantum quenches in integrable impurity systems, combining a mapping onto a boundary problem with the form factor approach to boundary-condition-changing operators introduced by Lesage and Saleur [Phys. Rev. Lett. 80, 4370 (1998)]. We discuss how to compute exactly the following two central quantities of interest: the Loschmidt echo and the distribution of the work done during the quantum quench. Our results display an interesting crossover physics characterized by the energy scale T(b) of the impurity corresponding to the Kondo temperature. We discuss in detail the noninteracting case as a paradigm and benchmark for more complicated integrable impurity models and check our results using numerical methods.

  3. Minimum quench energy measurement for superconducting wires

    International Nuclear Information System (INIS)

    Seo, K.; Morita, M.; Nakamura, S.; Yamada, T.; Jizo, Y.

    1996-01-01

    The authors have developed a new method of measuring minimum quench energy (MQE) of superconducting wire. There have been conventional methods using heating wires, whose diameters are ∼0.1mm and are glued by epoxy resin. When they induce a pulse heat to superconducting wires, a duration of the pulse must be several hundreds micro seconds to demonstrate actual disturbances (for instance wire motion) in a superconducting magnet. In spite of this fact, thermal diffusion time constants of the conventional heaters are larger than the duration of the actual disturbance, because of these electrical insulator of the heating wire and the epoxy bind. Therefore, this kind of heater is not able to demonstrate the actual disturbance. To solve this problem, they have proposed a new constitution of a heater. In the method, heat generation is introduced in high resistive layer on a surface of a superconducting wire. The high resistive layer is consist of carbon paste. The thickness of the carbon paste layer is ∼20microm, thus a time constant of this heater is expected to be small enough to demonstrate the actual disturbance. Adopting the new method to the MQE measurement, they successfully evaluate MQE of superconducting wires with high precision. Several results are introduced in this paper

  4. Role of QCD monopoles in jet quenching

    Science.gov (United States)

    Ramamurti, Adith; Shuryak, Edward

    2018-01-01

    QCD monopoles are magnetically charged quasiparticles whose Bose-Einstein condensation (BEC) at T electric confinement and flux tubes. The "magnetic scenario" of QCD proposes that scattering on the noncondensed component of the monopole ensemble at T >Tc is responsible for the unusual kinetic properties of quark-gluon plasma. In this paper, we study the contribution of the monopoles to jet quenching phenomenon, using the Baier-Dokshitzer-Mueller-Peigne-Schiff framework and hydrodynamic backgrounds. In the lowest order for cross sections, we calculate the nuclear modification factor, RAA, and azimuthal anisotropy, v2, of jets, as well as the dijet asymmetry, Aj, and compare those to the available data. We find relatively good agreement with experiment when using realistic hydrodynamic backgrounds. In addition, we find that event-by-event fluctuations are not necessary to reproduce RAA and v2 data, but play a role in Aj. Since the monopole-induced effects are maximal at T ≈Tc, we predict that their role should be significantly larger, relative to quarks and gluons, at lower RHIC energies.

  5. Quorum Quenching Agents: Resources for Antivirulence Therapy

    Directory of Open Access Journals (Sweden)

    Kaihao Tang

    2014-05-01

    Full Text Available The continuing emergence of antibiotic-resistant pathogens is a concern to human health and highlights the urgent need for the development of alternative therapeutic strategies. Quorum sensing (QS regulates virulence in many bacterial pathogens, and thus, is a promising target for antivirulence therapy which may inhibit virulence instead of cell growth and division. This means that there is little selective pressure for the evolution of resistance. Many natural quorum quenching (QQ agents have been identified. Moreover, it has been shown that many microorganisms are capable of producing small molecular QS inhibitors and/or macromolecular QQ enzymes, which could be regarded as a strategy for bacteria to gain benefits in competitive environments. More than 30 species of marine QQ bacteria have been identified thus far, but only a few of them have been intensively studied. Recent studies indicate that an enormous number of QQ microorganisms are undiscovered in the highly diverse marine environments, and these marine microorganism-derived QQ agents may be valuable resources for antivirulence therapy.

  6. Central implementation strategies outperform local ones in improving HIV testing in Veterans Healthcare Administration facilities.

    Science.gov (United States)

    Goetz, Matthew Bidwell; Hoang, Tuyen; Knapp, Herschel; Burgess, Jane; Fletcher, Michael D; Gifford, Allen L; Asch, Steven M

    2013-10-01

    Pilot data suggest that a multifaceted approach may increase HIV testing rates, but the scalability of this approach and the level of support needed for successful implementation remain unknown. To evaluate the effectiveness of a scaled-up multi-component intervention in increasing the rate of risk-based and routine HIV diagnostic testing in primary care clinics and the impact of differing levels of program support. Three arm, quasi-experimental implementation research study. Veterans Health Administration (VHA) facilities. Persons receiving primary care between June 2009 and September 2011 INTERVENTION: A multimodal program, including a real-time electronic clinical reminder to facilitate HIV testing, provider feedback reports and provider education, was implemented in Central and Local Arm Sites; sites in the Central Arm also received ongoing programmatic support. Control Arm sites had no intervention Frequency of performing HIV testing during the 6 months before and after implementation of a risk-based clinical reminder (phase I) or routine clinical reminder (phase II). The adjusted rate of risk-based testing increased by 0.4 %, 5.6 % and 10.1 % in the Control, Local and Central Arms, respectively (all comparisons, p marketing significantly increased the frequency at which HIV testing is offered and performed in VHA facilities. These findings support a multimodal approach toward achieving the goal of having every American know their HIV status as a matter of routine clinical practice.

  7. Towards improved magnetic fluid hyperthermia: major-loops to diminish variations in local heating.

    Science.gov (United States)

    Munoz-Menendez, Cristina; Serantes, David; Ruso, Juan M; Baldomir, Daniel

    2017-06-07

    In the context of using magnetic nanoparticles for heat-mediated applications, the need of an accurate knowledge of the local (at the nanoparticle level) heat generation in addition to the usually studied global counterpart has been recently highlighted. Such a need requires accurate knowledge of the links among the intrinsic particle properties, system characteristics and experimental conditions. In this work we have investigated the role of the particles' anisotropy polydispersity in relation to the amplitude (H max ) of the AC magnetic field using a Monte Carlo technique. Our results indicate that it is better to use particles with large anisotropy for enhancing global heating, whereas for achieving homogeneous local heating it is better to use lower anisotropy particles. The latter ensures that most of the system undergoes major-loop hysteresis conditions, which is the key-point. This is equivalent to say that low-anisotropy particles (i.e. with less heating capability) may be better for accurate heat-mediated applications, which goes against some research trends in the literature that seek for large anisotropy (and hence heating) values.

  8. Use of a novel smart heating sleeping bag to improve wearers’ local thermal comfort in the feet

    Science.gov (United States)

    Song, W. F.; Zhang, C. J.; Lai, D. D.; Wang, F. M.; Kuklane, K.

    2016-01-01

    Previous studies have revealed that wearers had low skin temperatures and cold and pain sensations in the feet, when using sleeping bags under defined comfort and limit temperatures. To improve wearers’ local thermal comfort in the feet, a novel heating sleeping bag (i.e., MARHT) was developed by embedding two heating pads into the traditional sleeping bag (i.e., MARCON) in this region. Seven female and seven male volunteers underwent two tests on different days. Each test lasted for three hours and was performed in a climate chamber with a setting temperature deduced from EN 13537 (2012) (for females: comfort temperature of -0.4 °C, and for males: the limit temperature of -6.4 °C). MARHT was found to be effective in maintaining the toe and feet temperatures within the thermoneutral range for both sex groups compared to the linearly decreased temperatures in MARCON during the 3-hour exposure. In addition, wearing MARHT elevated the toe blood flow significantly for most females and all males. Thermal and comfort sensations showed a large improvement in feet and a small to moderate improvement in the whole body for both sex groups in MARHT. It was concluded that MARHT is effective in improving local thermal comfort in the feet.

  9. Federal School Improvement Grants (SIGs): How Capacity and Local Conditions Matter

    Science.gov (United States)

    Yatsko, Sarah; Lake, Robin; Bowen, Melissa; Cooley Nelson, Elizabeth

    2015-01-01

    In 2009, the federal government committed over $3 billion nationwide to help states and districts turn around their worst-performing schools. The U.S. Department of Education intended for the School Improvement Grants (SIGs) to spur dramatic change.This report looks at the results of a field study of the first-year implementation of those grants…

  10. Histamine, a vasoactive agent with vascular disrupting potential, improves tumour response by enhancing local drug delivery

    NARCIS (Netherlands)

    F. Brunstein (Flavia); J.A.P. Rens (Joost); S.T. van Tiel (Sandra); A.M.M. Eggermont (Alexander); T.L.M. ten Hagen (Timo)

    2006-01-01

    textabstractTumour necrosis factor (TNF)-based isolated limb perfusion (ILP) is an approved and registered treatment for sarcomas confined to the limbs in Europe since 1998, with limb salvage indexes of 76%. TNF improves drug distribution in solid tumours and secondarily destroys the

  11. Partnering with a local concrete block manufacturing plant to improve quality of construction materials in Haiti’s Central Plateau

    Directory of Open Access Journals (Sweden)

    Aaron Gordon

    2016-09-01

    Full Text Available This paper presents a successful ongoing partnership between Clemson Engineers for Developing Countries (CEDC and a concrete masonry unit (CMU manufacturing plant in rural Haiti. The infrastructure destruction and resulting loss of life of the 2010 earthquake in Haiti highlighted the need for improved building materials and codes. This partnership has helped to improve the strength of CMUs in the plant, both creating a safer local built environment and expanding the economic opportunities for this plant. Using samples of aggregate and cement from the site in Haiti, students in Clemson performed experiments to optimise the CMU mix design and made other suggestions to improve efficiency and quality of their product. Consistency continues to be a challenge for the CMU plant, and this paper also describes proposed procedures to help the plant implement quality control and quality assurance plans.

  12. The FSM technology -- Operational experience and improvements in local corrosion analysis

    International Nuclear Information System (INIS)

    Stroemmen, R.; Horn, H.; Gartland, P.O.; Wold, K.

    1996-01-01

    FSM (Field Signature Method) is a non-intrusive monitoring technique based on a patented principle, developed for the purpose of detection and monitoring of both general and localized corrosion, erosion and cracking in steel and metal structures, piping systems and vessels. Since 1991 FSM has been used for a wide range of applications e.g. for buried and open pipelines, process piping offshore, subsea pipelines and flowlines, applications in the nuclear power industry and in materials research in general. This paper describes typical applications of the FSM technology, and presents operational experience from some of the landbased and subsea installations. The paper also describes recent enhancements in the FSM technology and in the analysis of FSM readings, allowing for monitoring and detailed quantification of pitting and mesa corrosion, and of corrosion in welds

  13. Does local government staff perceive digital communication with citizens as improved service?

    DEFF Research Database (Denmark)

    Berger, Jesper B.; Hertzum, Morten; Schreiber, Trine Louise

    2016-01-01

    Digital communication between government and citizens is pivotal to e-government. The Danish e-government initiative Digital Post aims to digitize all communication between government and citizens. We surveyed local government staff about how Digital Post affects the service delivered to citizens....... As much as 82% of the 448 respondents considered digital communication with citizens using Digital Post a good idea, yet 47% reported concrete incidents in which they perceived a decrease in service with Digital Post. This result shows the importance of distinguishing between the overall service...... relationship and the concrete incidents of which the service consists. We discuss interactions between the relationship level and the incident level of Digital Post on the basis of a content analysis of the respondents’ incident descriptions....

  14. Local-Area Based Traffic Splitter for Improving Performance Using Subnetting

    Science.gov (United States)

    Yadav, Meenakshi; Mittal, Mohit Kumar

    2010-11-01

    This document provides an overview of LAN traffic splitter. The tool "Local-Area based Traffic splitter" is based on subnetting techniques. It is basically used for calculating subnets for sub-dividing the LAN. Subnetting an IP Network can be done for a variety of reasons, including organization, use of different physical media (such as Ethernet, FDDI, WAN, etc.), preservation of address space, and security. The most common reason is to control network traffic. There are various techniques for calculating subnets that are considered by this tool. This paper will explore the various features of this tool and will also check the effect of subnetting after implementing it on the LAN. These instructions give you basic guidelines for preparing camera-ready papers for conference proceedings.

  15. A new local thickening reverse spiral origami thin-wall construction for improving of energy absorption

    Science.gov (United States)

    Kong, C. H.; Zhao, X. L.; Hagiwara, I. R.

    2018-02-01

    As an effective and representative origami structure, reverse spiral origami structure can be capable to effectively take up energy in a crash test. The origami structure has origami creases thus this can guide the deformation of structure and avoid of Euler buckling. Even so the origami creases also weaken the support force and this may cut the absorption of crash energy. In order to increase the supporting capacity of the reverse spiral origami structure, we projected a new local thickening reverse spiral origami thin-wall construction. The reverse spiral origami thin-wall structure with thickening areas distributed along the longitudinal origami crease has a higher energy absorption capacity than the ordinary reverse spiral origami thin-wall structure.

  16. Radioluminescence quenching of toluene scintillators by methyl methacrylate

    International Nuclear Information System (INIS)

    Polacki, Z.

    1985-01-01

    It was established that singlet electronic excited state of toluene is quenched by methyl methacrylate (MMA) but not by PMMA. The value of quenching rate constant ksub(q)=0,6x10sup(9) 1.molsup(-1).ssup(-1) indicates that the quenching is a diffusion controlled process. It is assumed that the excitation energy of toluene sensitizes the polymerization process of MMA. The increase of radioluminescence intensity and quantum yield of excitation energy transfer is the result of diminishing the quantity of MMA in the solution during polymerization time. (author)

  17. Non-self-averaging nucleation rate due to quenched disorder

    International Nuclear Information System (INIS)

    Sear, Richard P

    2012-01-01

    We study the nucleation of a new thermodynamic phase in the presence of quenched disorder. The quenched disorder is a generic model of both impurities and disordered porous media; both are known to have large effects on nucleation. We find that the nucleation rate is non-self-averaging. This is in a simple Ising model with clusters of quenched spins. We also show that non-self-averaging behaviour is straightforward to detect in experiments, and may be rather common. (fast track communication)

  18. Fundamental Asymmetry in Quenches Between Integrable and Nonintegrable Systems.

    Science.gov (United States)

    Rigol, Marcos

    2016-03-11

    We study quantum quenches between integrable and nonintegrable hard-core boson models in the thermodynamic limit with numerical linked cluster expansions. We show that while quenches in which the initial state is a thermal equilibrium state of an integrable model and the final Hamiltonian is nonintegrable (quantum chaotic) lead to thermalization, the reverse is not true. While this might appear counterintuitive given the fact that the eigenstates of both Hamiltonians are related by a unitary transformation, we argue that it is generic. Hence, the lack of thermalization of integrable systems is robust against quenches starting from stationary states of nonintegrable ones. Nonintegrable systems thermalize independently of the nature of the initial Hamiltonian.

  19. Does Contrast-Enhanced Cervical Ultrasonography Improve Preoperative Localization Results in Patients With Sporadic Primary Hyperparathyroidism?

    Directory of Open Access Journals (Sweden)

    Elias Karakas

    2012-01-01

    Full Text Available Objective: Pre-operative localization studies are inevitable in patients with primary hyperparathyroidism (pHPT, who are eligible for focused or minimally invasive parathyroidectomy (MIP. High-resolution ultrasonography (US in combination with planar 99m Tc-Sestamibi-scintigraphy (MIBI and additional single-photon emission computed tomography (SPECT are the standard procedures to localize enlarged parathyroid glands. Our aim was to evaluate the practicability and significance of contrast-enhanced ultrasonography (CEUS in patients with pHPT. Materials and Methods: All investigations were performed at the University Hospital Marburg. Totally, 25 patients with biochemical proven pHPT underwent preoperative US, MIBI/SPECT, and CEUS. For CEUS, a suspension of phospholipid-stabilized sulfur-hexafluoride (SF6 microbubbles in combination with a special 12 MHz linear US probe was used. All patients were investigated by two sonographers, who did not get to view the findings noted by the other. Finally, surgery was performed and histopathological results were obtained from 24 patients. Results: In 17 (68% patients, US and MIBI/SPECT already raised suspicion of parathyroid lesions and all suspected lesions were reassessed by CEUS. However, no additional information was obtained using CEUS. Especially in eight patients with negative or inconsistent US and MIBI/SPECT results, CEUS did not provide additional information regarding the site of the suspected parathyroid adenoma. Overall, no side effects were observed using CEUS. Surgical cure was achieved in all patients. Conclusion: In this limited cohort of patients, no additional information could be obtained using the costly CEUS compared to results of US and MIBI/SPECT.

  20. Improving Biomaterials Imaging for Nanotechnology: Rapid Methods for Protein Localization at Ultrastructural Level.

    Science.gov (United States)

    Cano-Garrido, Olivia; Garcia-Fruitós, Elena; Villaverde, Antonio; Sánchez-Chardi, Alejandro

    2018-04-01

    The preparation of biological samples for electron microscopy is material- and time-consuming because it is often based on long protocols that also may produce artifacts. Protein labeling for transmission electron microscopy (TEM) is such an example, taking several days. However, for protein-based nanotechnology, high resolution imaging techniques are unique and crucial tools for studying the spatial distribution of these molecules, either alone or as components of biomaterials. In this paper, we tested two new short methods of immunolocalization for TEM, and compared them with a standard protocol in qualitative and quantitative approaches by using four protein-based nanoparticles. We reported a significant increase of labeling per area of nanoparticle in both new methodologies (H = 19.811; p < 0.001) with all the model antigens tested: GFP (H = 22.115; p < 0.001), MMP-2 (H = 19.579; p < 0.001), MMP-9 (H = 7.567; p < 0.023), and IFN-γ (H = 62.110; p < 0.001). We also found that the most suitable protocol for labeling depends on the nanoparticle's tendency to aggregate. Moreover, the shorter methods reduce artifacts, time (by 30%), residues, and reagents hindering, losing, or altering antigens, and obtaining a significant increase of protein localization (of about 200%). Overall, this study makes a step forward in the development of optimized protocols for the nanoscale localization of peptides and proteins within new biomaterials. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Integrated Modeling of the Human-Natural System to Improve Local Water Management and Planning

    Science.gov (United States)

    Gutowski, W. J., Jr.; Dziubanski, D.; Franz, K.; Goodwin, J.; Rehmann, C. R.; Simpkins, W. W.; Tesfastion, L.; Wanamaker, A. D.; Jie, Y.

    2015-12-01

    Communities across the world are experiencing the effects of unsustainable water management practices. Whether the problem is a lack of water, too much water, or water of degraded quality, finding acceptable solutions requires community-level efforts that integrate sound science with local needs and values. Our project develops both a software technology (agent-based hydrological modeling) and a social technology (a participatory approach to model development) that will allow communities to comprehensively address local water challenges. Using agent-based modeling (ABM), we are building a modeling system that includes a semi-distributed hydrologic process model coupled with agent (stakeholder) models. Information from the hydrologic model is conveyed to the agent models, which, along with economic information, determine appropriate agent actions that subsequently affect hydrology within the model. The iterative participatory modeling (IPM) process will assist with the continual development of the agent models. Further, IPM creates a learning environment in which all participants, including researchers, are co-exploring relevant data, possible scenarios and solutions, and viewpoints through continuous interactions. Our initial work focuses on the impact of flood mitigation and conservation efforts on reducing flooding in an urban area. We are applying all research elements above to the Squaw Creek watershed that flows through parts of four counties in central Iowa. The watershed offers many of the typical tensions encountered in Iowa, such as different perspectives on water management between upstream farmers and downstream urban areas, competition for various types of recreational services, and increasing absentee land ownership that may conflict with community values. Ultimately, climate change scenarios will be incorporated into the model to determine long term patterns that may develop within the social or natural system.

  2. Residual stress measurement by neutron diffraction inside a steel bar quenched after induction heating

    International Nuclear Information System (INIS)

    Tokuda, Harukiyo; Tomota, Yo; Suzuki, Tetsuya; Kawasaki, Kazuhiro; Moriai, Atsushi; Minakawa, Nobuaki; Morii, Yukio

    2004-01-01

    The residual stress of a quenched steel bar with induction heating was measured by neutron diffraction. The conventional X-ray sin 2 ψ method was also used and three dimensional stress condition was estimated from plane-stress data obtained by a progressive polishing technique. Good agreements were found between the results by the neutron and X-ray methods. Improvements of the neutron stress measurement discussed. (author)

  3. Assessing and improving the spatial accuracy in MEG source localization by depth-weighted minimum-norm estimates.

    Science.gov (United States)

    Lin, Fa-Hsuan; Witzel, Thomas; Ahlfors, Seppo P; Stufflebeam, Steven M; Belliveau, John W; Hämäläinen, Matti S

    2006-05-15

    Cerebral currents responsible for the extra-cranially recorded magnetoencephalography (MEG) data can be estimated by applying a suitable source model. A popular choice is the distributed minimum-norm estimate (MNE) which minimizes the l2-norm of the estimated current. Under the l2-norm constraint, the current estimate is related to the measurements by a linear inverse operator. However, the MNE has a bias towards superficial sources, which can be reduced by applying depth weighting. We studied the effect of depth weighting in MNE using a shift metric. We assessed the localization performance of the depth-weighted MNE as well as depth-weighted noise-normalized MNE solutions under different cortical orientation constraints, source space densities, and signal-to-noise ratios (SNRs) in multiple subjects. We found that MNE with depth weighting parameter between 0.6 and 0.8 showed improved localization accuracy, reducing the mean displacement error from 12 mm to 7 mm. The noise-normalized MNE was insensitive to depth weighting. A similar investigation of EEG data indicated that depth weighting parameter between 2.0 and 5.0 resulted in an improved localization accuracy. The application of depth weighting to auditory and somatosensory experimental data illustrated the beneficial effect of depth weighting on the accuracy of spatiotemporal mapping of neuronal sources.

  4. Analysis of prostate cancer localization toward improved diagnostic accuracy of transperineal prostate biopsy

    Directory of Open Access Journals (Sweden)

    Yoshiro Sakamoto

    2014-09-01

    Conclusions: The concordance of prostate cancer between prostatectomy specimens and biopsies is comparatively favorable. According to our study, the diagnostic accuracy of transperineal prostate biopsy can be improved in our institute by including the anterior portion of the Apex-Mid and Mid regions in the 12-core biopsy or 16-core biopsy, such that a 4-core biopsy of the anterior portion is included.

  5. Healthy citizens and building projects. What can be realized by administrators improving local air quality

    International Nuclear Information System (INIS)

    Hoekstra, B.; Woudenberg, F.

    2006-01-01

    European regulations with respect to air quality in urban areas forces national governments to follow those regulations in case of spatial planning, building and construction projects. Many of those plans in the Netherlands do not meet those regulations and appear to exceed the boundary values of emission and the quality of ambient air. Therefor building and construction projects can not start or be finalized. In this article an overview is given of possibilities to improve the air quality [nl

  6. Improving safety and operational efficiency in residential care settings with WiFi-based localization.

    Science.gov (United States)

    Doshi-Velez, Finale; Li, William; Battat, Yoni; Charrow, Ben; Curtis, Dorothy; Curthis, Dorothy; Park, Jun-geun; Hemachandra, Sachithra; Velez, Javier; Walsh, Cynthia; Fredette, Don; Reimer, Bryan; Roy, Nicholas; Teller, Seth

    2012-07-01

    To assess the effectiveness of a wireless network (WiFi-based) localization system (devices mounted on resident wheelchairs) in decreasing caretaker time spent searching for residents and providing alerts of residents going outdoors in a skilled nursing facility. A controlled study over two 2-month periods approved by the institutional review board. A long-term skilled nursing facility in Massachusetts specializing in multiple sclerosis previously instrumented with wireless network infrastructure. Nineteen residents and 9 staff members at the facility for the first 2-month period; 9 residents and 3 staff members at the facility for the second 2-month period. Software was installed on 4 staff computers to display the locations of residents enrolled in the study. This software was made available to enrolled staff for the second half of the first 2-month period and the entirety of the second 2-month study. In the second 2-month study, the software was modified to provide alerts if any 1 of 9 participating "high-risk"' residents went outdoors, and the accuracy of the alert system was evaluated. In the first 2-month study, 9 staff members recorded the amount of time it took them to locate participating residents (as and when needed during the course of their daily activities). In the second 2-month study, 3 staff members recorded whether outdoor-alerts correctly identified a resident leaving the building or if it was a false alarm. In both phases, participating staff members made frequent use of the system (44 searches and 215 outdoor alerts). Overall, the localization information decreased the average time needed to find residents by about two-thirds (from 311.1 seconds to 110.9 seconds). For outdoor alerts, the system had a false-alarm rate of 9.1% (under normal facility operations); systematic tests of the outdoor-alert system carried out by the authors had a false-negative, or missed-alarm, rate of 1.7%. Using timely resident location information can provide

  7. Local Administration of Interleukin-1 Receptor Antagonist Improves Diabetic Wound Healing.

    Science.gov (United States)

    Perrault, David P; Bramos, Athanasios; Xu, Xingtian; Shi, Songtao; Wong, Alex K

    2018-03-16

    Impaired healing of the skin is a notable cause of patient morbidity and mortality. In diabetic individuals, dysregulated inflammation contributes to delayed wound healing. Specific immunomodulatory agents may have a role in the treatment of diabetic wounds. One of these molecules is interleukin-1 receptor antagonist (Anakinra; Amgen Corp.). Although interleukin-1 receptor antagonist (Anakinra; Amgen Corp.) is approved by the Food and Drug Administration (FDA) for the treatment of rheumatoid arthritis and neonatal-onset multisystem inflammatory disease, little is known about the local use this drug in cutaneous wound healing. Therefore, the aim of this study is to determine the effect of locally administered interleukin-1 receptor antagonist on delayed wound healing, specifically, in a diabetic mouse model. Two 6-mm full-thickness wounds were created on the dorsa of diabetic (db/db) mice and stented. One-hour postwounding, wound margins were subcutaneously injected with either (1) low-dose interleukin-1 receptor antagonist in a gelatin-transglutaminase gel vehicle or (2) the gel vehicle only. Wounds were imaged on days 0, 7, 14, and 21 postwounding, and wound area was determined. Wound biopsies were collected on day 21 and immunohistochemically stained for neutrophil and macrophage infiltration. Wounds treated with interleukin-1 receptor antagonist had significantly smaller wound area than nontreated wounds on day 7 and day 14 postwounding. Treated wounds also showed significantly less neutrophil and macrophage infiltration. These findings support the hypothesis that interleukin-1 receptor antagonist may have an important role in cutaneous wound healing, possibly by promoting successful resolution of acute inflammation and hence accelerating wound closure. Thereby, administration of IL-1Ra may be useful in the treatment of nonhealing wounds.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives

  8. Quenching simulation of steel grinding balls

    Directory of Open Access Journals (Sweden)

    Zapata-Hernández, Oscar

    2015-09-01

    Full Text Available The phase transformations of high carbon steel during quenching and equalizing were modelled using commercial computer packages based on the finite element method and the kinetic transformation of steel. The model was used to predict the temperature and microstructural changes taking place within balls of two different sizes that are used for grinding mineral ores. A good correlation between the temperatures measured by inserted thermocouples and those predicted by the model was obtained after modifying the thermal conductivity of the steel within the temperature domain at which mixed phases are present. The phase transformations predicted were confirmed by metallographic analyses.Las transformaciones de fase en aceros de alto carbono durante su temple y un posterior periodo de estabilización fueron modelizadas por medio del uso de paquetes computacionales basados en el método del elemento finito y de la transformación cinética de los aceros. El modelo se usó para predecir los cambios de temperatura y microestructura que se presentan en bolas de dos diferentes tamaños empleadas en estaciones de molienda de minerales. Se encontró una buena correlación entre las temperaturas medidas mediante la inserción de termopares y aquellas predichas por el modelo una vez que se modificó la conductividad térmica del acero en el intervalo mixto de fases. La predicción de las transformaciones de fase se confirmó a través del análisis metalográfico.

  9. Improving maternal and neonatal departments in high and low resource settings: the opinion of local health providers.

    Science.gov (United States)

    Trevisanuto, Daniele; Bavuusuren, Bayasgalantai; Wickramasinghe, Chandani S; Dharmaratne, Saminda M; Doglioni, Nicoletta; Giordan, Alessia; Zanardo, Vincenzo; Carlo, Waldemar A

    2011-10-01

    We compared local health caregivers' opinions regarding the priority areas for improving the maternal and neonatal departments in low and high resource countries. Personnel involved in maternal and neonatal care operating in level III, teaching hospitals in four countries (Sri Lanka, Mongolia, USA, and Italy) were asked to fill out an anonymous, written questionnaire. The questionnaire was completed by 1112 out of 1265 (87.9%) participants. "Personnel's education" was classified as the first most important intervention by health providers working in high (49.0%) as well as in low (29.9%) resource countries, respectively. Improvement in salary, equipment, internet access, and organizational protocols were considered as the most important interventions by a significantly larger percentage of personnel from low resource countries in comparison with those from high resource countries. Health providers from high resource countries considered organizational aspects (to define specific roles and responsibilities) as a priority more frequently than their colleagues from low resource countries. Although education of personnel was valued as the highest priority for improving maternal and neonatal departments there are substantial differences in priorities associated with the working setting. Local caregivers' opinion may contribute to better design interventions in settings with high or limited resources.

  10. Improved outcome of treating locally advanced lung cancer with the use of Lattice Radiotherapy (LRT: A case report

    Directory of Open Access Journals (Sweden)

    Beatriz E. Amendola

    2018-02-01

    Full Text Available The Lattice Radiotherapy (LRT technique is mainly based on the GRID technology with the improved feature of the 3D treatment delivery. A 72 year old male presented with left shoulder pain due to a 6 cm pulmonary mass in the left upper lobe (LUL histologically proven Non-Small Cell Lung Cancer (NSCLC stage IIIA. In July 2011 he was treated in our center with LRT followed by conventional fractionated Volumetric Modulated Arc Therapy (VMAT combined with chemotherapy. Clinical and imaging follow up of 6 years demonstrated continued improvement and the patient is currently with no evidence of disease (NED. This outstanding result obtained in our first lung cancer patient treated with this approach corroborates its potential in the treatment of locally advanced lung cancer. In a period of 7 years we have treated more than 30 patients with LRT for different diagnosis and sites; 12 of them NSCLC patients, with markedly improved local control and minimal toxicity.

  11. Exploiting Deep Matching and SAR Data for the Geo-Localization Accuracy Improvement of Optical Satellite Images

    Directory of Open Access Journals (Sweden)

    Nina Merkle

    2017-06-01

    Full Text Available Improving the geo-localization of optical satellite images is an important pre-processing step for many remote sensing tasks like monitoring by image time series or scene analysis after sudden events. These tasks require geo-referenced and precisely co-registered multi-sensor data. Images captured by the high resolution synthetic aperture radar (SAR satellite TerraSAR-X exhibit an absolute geo-location accuracy within a few decimeters. These images represent therefore a reliable source to improve the geo-location accuracy of optical images, which is in the order of tens of meters. In this paper, a deep learning-based approach for the geo-localization accuracy improvement of optical satellite images through SAR reference data is investigated. Image registration between SAR and optical images requires few, but accurate and reliable matching points. These are derived from a Siamese neural network. The network is trained using TerraSAR-X and PRISM image pairs covering greater urban areas spread over Europe, in order to learn the two-dimensional spatial shifts between optical and SAR image patches. Results confirm that accurate and reliable matching points can be generated with higher matching accuracy and precision with respect to state-of-the-art approaches.

  12. Improvement of Inventory Control Using Continuous Review Policy in A Local Hospital at Bandung City, Indonesia

    Directory of Open Access Journals (Sweden)

    Fina Hafnika

    2016-12-01

    Full Text Available Abstract. This research was aimed to analyze the excess inventories issue in pharmacy and medical equipment unit at a local hospital in Bandung which affected the service level of the hospital. As one of the busy hospital in Java, proven by the higher amount of the patient/year than in other average Java typical hospital, the hospital needs to concern about the pharmaceutical and medical equipment inventories in order to fulfill patients’ needs and in the same time keeping the inventory level under control. Therefore, an inventory control evaluation was conducted to determine the appropriate number of inventories and time of order to avoid the excessive goods in central warehouse of the hospital. By using probabilistic inventory model and continuous review policy, the pharmaceutical inventory in the hospital was calculated to compare the ideal and actual amount of the average inventory level (AIL. ABC (Always, Better, Control classification also classified in this research to identify the proper item which potentially can be reduced from the inventory. From the analysis, we have discovered that the hospital potentially able to reduce almost Rp 830 million or 57% from the overstock inventory level by using continuous review policy as the basis of inventory control calculation system. Keywords: Continuous review policy, inventory control, EOQ, ROP, AIL

  13. Improving the accuracy of k-nearest neighbor using local mean based and distance weight

    Science.gov (United States)

    Syaliman, K. U.; Nababan, E. B.; Sitompul, O. S.

    2018-03-01

    In k-nearest neighbor (kNN), the determination of classes for new data is normally performed by a simple majority vote system, which may ignore the similarities among data, as well as allowing the occurrence of a double majority class that can lead to misclassification. In this research, we propose an approach to resolve the majority vote issues by calculating the distance weight using a combination of local mean based k-nearest neighbor (LMKNN) and distance weight k-nearest neighbor (DWKNN). The accuracy of results is compared to the accuracy acquired from the original k-NN method using several datasets from the UCI Machine Learning repository, Kaggle and Keel, such as ionosphare, iris, voice genre, lower back pain, and thyroid. In addition, the proposed method is also tested using real data from a public senior high school in city of Tualang, Indonesia. Results shows that the combination of LMKNN and DWKNN was able to increase the classification accuracy of kNN, whereby the average accuracy on test data is 2.45% with the highest increase in accuracy of 3.71% occurring on the lower back pain symptoms dataset. For the real data, the increase in accuracy is obtained as high as 5.16%.

  14. Improved radiological/nuclear source localization in variable NORM background: An MLEM approach with segmentation data

    Science.gov (United States)

    Penny, Robert D.; Crowley, Tanya M.; Gardner, Barbara M.; Mandell, Myron J.; Guo, Yanlin; Haas, Eric B.; Knize, Duane J.; Kuharski, Robert A.; Ranta, Dale; Shyffer, Ryan; Labov, Simon; Nelson, Karl; Seilhan, Brandon; Valentine, John D.

    2015-06-01

    A novel approach and algorithm have been developed to rapidly detect and localize both moving and static radiological/nuclear (R/N) sources from an airborne platform. Current aerial systems with radiological sensors are limited in their ability to compensate for variable naturally occurring radioactive material (NORM) background. The proposed approach suppresses the effects of NORM background by incorporating additional information to segment the survey area into regions over which the background is likely to be uniform. The method produces pixelated Source Activity Maps (SAMs) of both target and background radionuclide activity over the survey area. The task of producing the SAMs requires (1) the development of a forward model which describes the transformation of radionuclide activity to detector measurements and (2) the solution of the associated inverse problem. The inverse problem is ill-posed as there are typically fewer measurements than unknowns. In addition the measurements are subject to Poisson statistical noise. The Maximum-Likelihood Expectation-Maximization (MLEM) algorithm is used to solve the inverse problem as it is well suited for under-determined problems corrupted by Poisson noise. A priori terrain information is incorporated to segment the reconstruction space into regions within which we constrain NORM background activity to be uniform. Descriptions of the algorithm and examples of performance with and without segmentation on simulated data are presented.

  15. Experiments and improvements of ear recognition based on local texture descriptors

    Science.gov (United States)

    Benzaoui, Amir; Adjabi, Insaf; Boukrouche, Abdelhani

    2017-04-01

    The morphology of the human ear presents rich and stable information embedded on the curved 3-D surface and has as a result attracted considerable attention from forensic scientists and engineers as a biometric recognition modality. However, recognizing a person's identity from the morphology of the human ear in unconstrained environments, with insufficient and incomplete training data, strong person-specificity, and high within-range variance, can be very challenging. Following our previous work on ear recognition based on local texture descriptors, we propose to use anatomical and embryological information about the human ear in order to find the autonomous components and the locations where large interindividual variations can be detected. Embryology is particularly relevant to our approach as it provides information on the possible changes that can be observed in the external structure of the ear. We experimented with three publicly available databases, namely: IIT Delhi-1, IIT Delhi-2, and USTB-1, consisting of several ear benchmarks acquired under varying conditions and imaging qualities. The experiments show excellent results, beyond the state of the art.

  16. Does chronomodulated radiotherapy improve pathological response in locally advanced rectal cancer?

    Science.gov (United States)

    Squire, Tim; Buchanan, Grant; Rangiah, David; Davis, Ian; Yip, Desmond; Chua, Yu Jo; Rich, Tyvin; Elsaleh, Hany

    2017-01-01

    The predominant mode of radiation-induced cell death for solid tumours is mitotic catastrophe, which is in part dependent on sublethal damage repair being complete at around 6 h. Circadian variation appears to play a role in normal cellular division, and this could influence tumour response of radiation treatment depending on the time of treatment delivery. We tested the hypothesis that radiation treatment later in the day may improve tumour response and nodal downstaging in rectal cancer patients treated neoadjuvantly with radiation therapy. Recruitment was by retrospective review of 267 rectal cancer patients treated neoadjuvantly in the Department of Radiation Oncology at the Canberra Hospital between January 2010 and November 2015. One hundred and fifty-five patients met the inclusion criteria for which demographic, pathological and imaging data were collected, as well as the time of day patients received treatment with each fraction of radiotherapy. Data analysis was performed using the Statistical Package R with nonparametric methods of significance for all tests set at p rectal cancer performed later in the day coupled with a longer time period to surgical resection may improve pathological tumour response rates and nodal downstaging. A prospective study in chronomodulated radiotherapy in this disease is warranted.

  17. An Improved BLE Indoor Localization with Kalman-Based Fusion: An Experimental Study.

    Science.gov (United States)

    Röbesaat, Jenny; Zhang, Peilin; Abdelaal, Mohamed; Theel, Oliver

    2017-04-26

    Indoor positioning has grasped great attention in recent years. A number of efforts have been exerted to achieve high positioning accuracy. However, there exists no technology that proves its efficacy in various situations. In this paper, we propose a novel positioning method based on fusing trilateration and dead reckoning. We employ Kalman filtering as a position fusion algorithm. Moreover, we adopt an Android device with Bluetooth Low Energy modules as the communication platform to avoid excessive energy consumption and to improve the stability of the received signal strength. To further improve the positioning accuracy, we take the environmental context information into account while generating the position fixes. Extensive experiments in a testbed are conducted to examine the performance of three approaches: trilateration, dead reckoning and the fusion method. Additionally, the influence of the knowledge of the environmental context is also examined. Finally, our proposed fusion method outperforms both trilateration and dead reckoning in terms of accuracy: experimental results show that the Kalman-based fusion, for our settings, achieves a positioning accuracy of less than one meter.

  18. An Improved BLE Indoor Localization with Kalman-Based Fusion: An Experimental Study

    Directory of Open Access Journals (Sweden)

    Jenny Röbesaat

    2017-04-01

    Full Text Available Indoor positioning has grasped great attention in recent years. A number of efforts have been exerted to achieve high positioning accuracy. However, there exists no technology that proves its efficacy in various situations. In this paper, we propose a novel positioning method based on fusing trilateration and dead reckoning. We employ Kalman filtering as a position fusion algorithm. Moreover, we adopt an Android device with Bluetooth Low Energy modules as the communication platform to avoid excessive energy consumption and to improve the stability of the received signal strength. To further improve the positioning accuracy, we take the environmental context information into account while generating the position fixes. Extensive experiments in a testbed are conducted to examine the performance of three approaches: trilateration, dead reckoning and the fusion method. Additionally, the influence of the knowledge of the environmental context is also examined. Finally, our proposed fusion method outperforms both trilateration and dead reckoning in terms of accuracy: experimental results show that the Kalman-based fusion, for our settings, achieves a positioning accuracy of less than one meter.

  19. Quenched noise and nonlinear oscillations in bistable multiscale systems

    Science.gov (United States)

    Kuehn, C.

    2017-10-01

    Nonlinear oscillators are a key modelling tool in many applications. The influence of annealed noise on nonlinear oscillators has been studied intensively. It can induce effects in nonlinear oscillators not present in the deterministic setting. Yet, there is no theory regarding the quenched noise scenario of random parameters sampled on fixed time intervals, although this situation is often a lot more natural. Here we study a paradigmatic nonlinear oscillator of van-der-Pol/FitzHugh-Nagumo type under quenched noise as a piecewise-deterministic Markov process. There are several interesting effects such as period shifts and new different trapped types of small-amplitude oscillations, which can be captured analytically. Furthermore, we numerically discover quenched resonance and show that it differs significantly from previous finite-noise optimality resonance effects. This demonstrates that quenched oscillators can be viewed as a new building block of nonlinear dynamics.

  20. Reliability analysis for the quench detection in the LHC machine

    CERN Document Server

    Denz, R; Vergara-Fernández, A

    2002-01-01

    The Large Hadron Collider (LHC) will incorporate a large amount of superconducting elements that require protection in case of a quench. Key elements in the quench protection system are the electronic quench detectors. Their reliability will have an important impact on the down time as well as on the operational cost of the collider. The expected rates of both false and missed quenches have been computed for several redundant detection schemes. The developed model takes account of the maintainability of the system to optimise the frequency of foreseen checks, and evaluate their influence on the performance of different detection topologies. Seen the uncertainty of the failure rate of the components combined with the LHC tunnel environment, the study has been completed with a sensitivity analysis of the results. The chosen detection scheme and the maintainability strategy for each detector family are given.

  1. Temperature profile evolution in quenching high-Tc ...

    Indian Academy of Sciences (India)

    temperature superconductors (HTS) in all practical applications. As a consequence of quench, transport current gets diverted to the matrix stabilizer material of the high-c composite and causes Joule heating till the original conditions are restored.

  2. Positronium quenching in liquid and solid octanol and benzene

    DEFF Research Database (Denmark)

    Shantarovich, V.P.; Mogensen, O.E.; Goldanskii, V.I.

    1970-01-01

    The lifetimes of orthopositronium in several solutions in liquid and solid octanol and benzene have been measured. The Ps-quenching constant was found to be two to thirty times higher in the solid than in the liquid phase....

  3. Measurement of cell volume changes by fluorescence self-quenching

    DEFF Research Database (Denmark)

    Hamann, Steffen; Kiilgaard, J.F.; Litman, Thomas

    2002-01-01

    At high concentrations, certain fluorophores undergo self-quenching, i.e., fluorescence intensity decreases with increasing fluorophore concentration. Accordingly, the self-quenching properties can be used for measuring water volume changes in lipid vesicles. In cells, quantitative determination...... of water transport using fluorescence self-quenching has been complicated by the requirement of relatively high (mM) and often toxic loading concentrations. Here we report a simple method that uses low (muM) loading concentrations of calcein-acetoxymethyl ester (calcein-AM) to obtain intracellular...... concentrations of the fluorophore calcein suitable for measurement of changes in cell water volume by self-quenching. The relationship between calcein fluorescence intensity, when excited at 490 nm (its excitation maximum), and calcein concentration was investigated in vitro and in various cultured cell types...

  4. Effects of austenitizing temperature in quenched niobium steels

    International Nuclear Information System (INIS)

    Mello, F.B.C. de; Assuncao, F.C.R.

    1980-01-01

    Three steel compositions with varying Nb content were austenitized at different temperatures and quenched in cold water. Metallographic examination and hardness measurements provided a basis for explaining the hardening mechanism and the role of Nb on the process. (Author) [pt

  5. Quantum quenches in the thermodynamic limit. II. Initial ground states

    Science.gov (United States)

    Rigol, Marcos

    2014-09-01

    A numerical linked-cluster algorithm was recently introduced to study quantum quenches in the thermodynamic limit starting from thermal initial states [M. Rigol, Phys. Rev. Lett. 112, 170601 (2014), 10.1103/PhysRevLett.112.170601]. Here, we tailor that algorithm to quenches starting from ground states. In particular, we study quenches from the ground state of the antiferromagnetic Ising model to the XXZ chain. Our results for spin correlations are shown to be in excellent agreement with recent analytical calculations based on the quench action method. We also show that they are different from the correlations in thermal equilibrium, which confirms the expectation that thermalization does not occur in general in integrable models even if they cannot be mapped to noninteracting ones.

  6. Magnetic properties of roller-quenched high silicon steel ribbons

    Science.gov (United States)

    Kan, T.; Ito, Y.; Shimanaka, H.

    1982-03-01

    The magnetic properties of high silicon steel ribbons prepared by the roller-quenching method were investigated, and this new material was considered to offer the potential of reducing core losses of electrical machines and power transformers.

  7. Simulation of the Quench-06 experiment with Scdapsim

    International Nuclear Information System (INIS)

    Angel M, E. del; Nunez C, A.; Amador G, R.

    2003-01-01

    The present work describes the pattern of the called Quench installation developed and used by the National Commission of Nuclear Security and Safeguards (CNSNS) for their participation in the International Standard Problem 45 (ISP), organized by the Nuclear Energy Agency (NEA). The exercise consisted on the simulation of the denominated experiment Quench-06 carried out in the experimental installation Quench located in the Forschungszentrum laboratory in Karlsruhe, Germany. The experiment Quench-06 consisted on simulating the sudden and late injection of water in a fuel assemble for a pressurized reactor (PWR). The CNSNS uses the version bd of the SCDAPSIM code developed by the company Innovative Software Systems (ISS) to simulate this experiment. The obtained results showed that the code is able to predict the experiment partially when overestimating the hydrogen production and of the partial fused of some fuel pellets, but predicting correctly the damage in the shroud. (Author)

  8. Controlling solid state gain media by deposition of silver nanoparticles: from thermally- quenched to plasmon-enhanced Nd(3+) luminescence.

    Science.gov (United States)

    Yraola, Eduardo; Sánchez-García, Laura; Tserkezis, Christos; Molina, Pablo; Ramírez, Mariola O; Plaza, Jose Luis; Aizpurua, Javier; Bausá, Luisa E

    2015-06-15

    We show the possibility of controlling the optical properties of Nd(3+) laser ions by using different configurations of metallic nanoparticles (NPs) deposited on a solid state gain medium. In particular, we analyze the effect of two different silver NP arrangements on the optical properties of Nd(3+) ions in LiNbO(3): a two-dimensional (2D) high density and disordered Ag NP distribution and a one-dimensional (1D) long single chain of Ag NPs. We demonstrate that while the 2D disordered distribution produces a thermal quenching of the Nd(3+) luminescence, the 1D single chain leads to the enhancement of the fluorescence from the (4)F(3/2) metastable state. The experimental data are theoretically interpreted by taking into account the different character, radiative or non-radiative, of the localized surface plasmonic modes supported by the Ag nanoparticle distributions at the excitation wavelength. The results point out the capabilities of rare earth ions as optical tools to probe the local plasmonic fields and are relevant to determine the optimal configuration of metallic arrays to improve the performance of potential rare earth ion based sub-micrometer lasers.

  9. Improved free-energy landscape reconstruction of bacteriorhodopsin highlights local variations in unfolding energy.

    Science.gov (United States)

    Heenan, Patrick R; Yu, Hao; Siewny, Matthew G W; Perkins, Thomas T

    2018-03-28

    Precisely quantifying the energetics that drive the folding of membrane proteins into a lipid bilayer remains challenging. More than 15 years ago, atomic force microscopy (AFM) emerged as a powerful tool to mechanically extract individual membrane proteins from a lipid bilayer. Concurrently, fluctuation theorems, such as the Jarzynski equality, were applied to deduce equilibrium free energies (ΔG 0 ) from non-equilibrium single-molecule force spectroscopy records. The combination of these two advances in single-molecule studies deduced the free-energy of the model membrane protein bacteriorhodopsin in its native lipid bilayer. To elucidate this free-energy landscape at a higher resolution, we applied two recent developments. First, as an input to the reconstruction, we used force-extension curves acquired with a 100-fold higher time resolution and 10-fold higher force precision than traditional AFM studies of membrane proteins. Next, by using an inverse Weierstrass transform and the Jarzynski equality, we removed the free energy associated with the force probe and determined the molecular free-energy landscape of the molecule under study, bacteriorhodopsin. The resulting landscape yielded an average unfolding free energy per amino acid (aa) of 1.0 ± 0.1 kcal/mol, in agreement with past single-molecule studies. Moreover, on a smaller spatial scale, this high-resolution landscape also agreed with an equilibrium measurement of a particular three-aa transition in bacteriorhodopsin that yielded 2.7 kcal/mol/aa, an unexpectedly high value. Hence, while average unfolding ΔG 0 per aa is a useful metric, the derived high-resolution landscape details significant local variation from the mean. More generally, we demonstrated that, as anticipated, the inverse Weierstrass transform is an efficient means to reconstruct free-energy landscapes from AFM data.

  10. Improved free-energy landscape reconstruction of bacteriorhodopsin highlights local variations in unfolding energy

    Science.gov (United States)

    Heenan, Patrick R.; Yu, Hao; Siewny, Matthew G. W.; Perkins, Thomas T.

    2018-03-01

    Precisely quantifying the energetics that drive the folding of membrane proteins into a lipid bilayer remains challenging. More than 15 years ago, atomic force microscopy (AFM) emerged as a powerful tool to mechanically extract individual membrane proteins from a lipid bilayer. Concurrently, fluctuation theorems, such as the Jarzynski equality, were applied to deduce equilibrium free energies (ΔG0) from non-equilibrium single-molecule force spectroscopy records. The combination of these two advances in single-molecule studies deduced the free-energy of the model membrane protein bacteriorhodopsin in its native lipid bilayer. To elucidate this free-energy landscape at a higher resolution, we applied two recent developments. First, as an input to the reconstruction, we used force-extension curves acquired with a 100-fold higher time resolution and 10-fold higher force precision than traditional AFM studies of membrane proteins. Next, by using an inverse Weierstrass transform and the Jarzynski equality, we removed the free energy associated with the force probe and determined the molecular free-energy landscape of the molecule under study, bacteriorhodopsin. The resulting landscape yielded an average unfolding free energy per amino acid (aa) of 1.0 ± 0.1 kcal/mol, in agreement with past single-molecule studies. Moreover, on a smaller spatial scale, this high-resolution landscape also agreed with an equilibrium measurement of a particular three-aa transition in bacteriorhodopsin that yielded 2.7 kcal/mol/aa, an unexpectedly high value. Hence, while average unfolding ΔG0 per aa is a useful metric, the derived high-resolution landscape details significant local variation from the mean. More generally, we demonstrated that, as anticipated, the inverse Weierstrass transform is an efficient means to reconstruct free-energy landscapes from AFM data.

  11. Quenched transmission of light through ultrathin metal films

    DEFF Research Database (Denmark)

    Xiao, Sanshui; Mortensen, N. Asger

    2011-01-01

    We discuss optical properties of ultrathin metal films, with particular attention to the phenomenon of quenched transmission. Transmission of light through an optically ultrathin metal film with a thickness comparable to its skin depth is significant. We demonstrate the quenched transmission...... through the ultrathin metal films when they are periodically modulated. We also discuss the physics behind it and explain how this abnormal phenomenon is ascribed to surface plasmon resonance effects....

  12. Quenching of g/sub A/ in the nuclear medium

    Energy Technology Data Exchange (ETDEWEB)

    Parthasarathy, R.; Pasupathy, J.

    1988-05-01

    The numerical values of g/sub A/ are evaluated using quantum-chromodynamic sum rules. The nuclear medium effects are taken into account by modifying the chiral symmetry breaking correlation, . Our results indicate a quenching of g/sub A/ in a nuclear medium. The physical reasons for this fundamental quenching are noted to be the same for the effective mass of the nucleon bound in a nucleus being less than its free space value.

  13. Chemical and colour quenching in liquid scintillation counting

    International Nuclear Information System (INIS)

    Scott G, P. E.; Grau M, A.

    1987-01-01

    Chemical and colour quenching for H-3 and C-14 was studied. The method includes spectral analysis of colouring agents; methyl red, (4'-dimethylamine-azobenzene 2-carboxylic acid) dimethyl yellow (4'-dimethylamine-azobenzene) and malachite green (methane, bis .(4-dimethyl aminophenyl) - (phenyl)). External standard channels ratio was applied for the liquid scintillation counting of samples. The introduction of an isolated external standard seems to be a strong tool for the correction of chemical and colour quenching curves. (Author) 12 refs

  14. Frequency loss induced quench protection system for high temperature superconductors

    Science.gov (United States)

    Ijagbemi, K.; Noyes, P.; Stiers, E.; Pamidi, S.

    2017-12-01

    A novel circuit design for Frequency Loss Induced Quench (FLIQ) protection system for safely driving REBCO coated conductor superconducting coils to quench is reported. The details of the H-bridge circuit design with Insulated Gate Bipolar Transistor (IGBT)s and the various elements used to build a prototype are reported. The results of a successful test of the circuit conducted to demonstrate the validity of the circuit design is presented.

  15. Remodularizing Java Programs for Improved Locality of Feature Implementations in Source Code

    DEFF Research Database (Denmark)

    Olszak, Andrzej; Jørgensen, Bo Nørregaard

    2011-01-01

    Explicit traceability between features and source code is known to help programmers to understand and modify programs during maintenance tasks. However, the complex relations between features and their implementations are not evident from the source code of object-oriented Java programs....... Consequently, the implementations of individual features are difficult to locate, comprehend, and modify in isolation. In this paper, we present a novel remodularization approach that improves the representation of features in the source code of Java programs. Both forward- and reverse restructurings...... are supported through on-demand bidirectional restructuring between feature-oriented and object-oriented decompositions. The approach includes a feature location phase based of tracing program execution, a feature representation phase that reallocates classes into a new package structure based on single...

  16. NASA MSFC Electrostatic Levitator (ESL) Rapid Quench System

    Science.gov (United States)

    SanSoucie, Michael P.; Craven, Paul D.

    2014-01-01

    Electrostatic levitation, a form of containerless processing, is an important tool in materials research. Levitated specimens are free from contact with a container; therefore, heterogeneous nucleation on container walls is not possible. This allows studies of deeply undercooled melts. Furthermore, studies of high-temperature, highly reactive materials are also possible. Studies of the solidification and crystallization of undercooled melts is vital to the understanding of microstructure development, particularly the formation of alloys with unique properties by rapid solidification. The NASA Marshall Space Flight Center (MSFC) Electrostatic Levitator (ESL) lab has recently been upgraded to allow for rapid quenching of levitated materials. The ESL Rapid Quench System uses a small crucible-like vessel that can be partially filled with a low melting point material, such as a Gallium alloy, as a quench medium. An undercooled sample can be dropped into the vessel to rapidly quench the sample. A carousel with nine vessels sits below the bottom electrode assembly. This system allows up to nine rapid quenches before having to break vacuum and remove the vessels. This new Rapid Quench System will allow materials science studies of undercooled materials and new materials development. In this presentation, the system is described and initial results are presented.

  17. A STELLAR MASS THRESHOLD FOR QUENCHING OF FIELD GALAXIES

    International Nuclear Information System (INIS)

    Geha, M.; Blanton, M. R.; Yan, R.; Tinker, J. L.

    2012-01-01

    We demonstrate that dwarf galaxies (10 7 stellar 9 M ☉ , –12 > M r > –18) with no active star formation are extremely rare ( Hα stellar 9 M ☉ below which quenched galaxies do not exist in the field. Below this threshold, we find that none of the 2951 field dwarf galaxies are quenched; all field dwarf galaxies show evidence for recent star formation. Correcting for volume effects, this corresponds to a 1σ upper limit on the quenched fraction of 0.06%. In more dense environments, quenched galaxies account for 23% of the dwarf population over the same stellar mass range. The majority of quenched dwarf galaxies (often classified as dwarf elliptical galaxies) are within 2 virial radii of a massive galaxy, and only a few percent of quenched dwarf galaxies exist beyond 4 virial radii. Thus, for galaxies with stellar mass less than 1.0 × 10 9 M ☉ , ending star formation requires the presence of a more massive neighbor, providing a stringent constraint on models of star formation feedback.

  18. Quench detection electronics testing protocol for SST-1 magnets

    International Nuclear Information System (INIS)

    Banaudha, Moni; Varmora, Pankaj; Parghi, Bhadresh; Prasad, Upendra

    2017-01-01

    Quench Detection (QD) system consisting 204 signal channels has been successfully installed and working well during plasma experiment of SST-1 Tokamak. QD system requires testing, validation and maintenance in every SST-1 campaign for better reliability and maintainability of the system. Standalone test of each channel of the system is essential for hard-ware validation. The standard Testing Protocol follow in every campaign which validate each section of QD electronics as well as voltage tap signal cables which are routed inside the cryostat and then extended outside of the SST-1 machine up-to the magnet control room. Fiber link for Quench signal transmission to the SST-1 magnet power supply is also test and validate before every plasma campaign. Precise instrument used as a dummy source of quench signal and for manual quench generation to test the each channel and Master Quench Logic. Each signal Integrated with the magnet DAQ system, signal observed at 1Hz and 50Hz configuration to validate the logging data, compare with actual and previous test data. This paper describes the testing protocol follow in every campaign to validate functionality of QD electronics, limitation of testing, test results and overall integration of the quench detection system for SST-1 magnet. (author)

  19. Exact steady states for quantum quenches in integrable Heisenberg spin chains

    Science.gov (United States)

    Piroli, Lorenzo; Vernier, Eric; Calabrese, Pasquale

    2016-08-01

    The study of quantum quenches in integrable systems has significantly advanced with the introduction of the quench action method, a versatile analytical approach to nonequilibrium dynamics. However, its application is limited to those cases where the overlaps between the initial state and the eigenstates of the Hamiltonian governing the time evolution are known exactly. Conversely, in this work we consider physically interesting initial states for which such overlaps are still unknown. In particular, we focus on different classes of product states in spin-1 /2 and spin-1 integrable chains, such as tilted ferromagnets and antiferromagnets. We get around the missing overlaps by following a recent approach based on the knowledge of complete sets of quasilocal charges. This allows us to provide a closed-form analytical characterization of the effective stationary state reached at long times after the quench, through the Bethe ansatz distributions of particles and holes. We compute the asymptotic value of local correlations and check our predictions against numerical data.

  20. [A classification method of gene expression profile based on a locally linear embedding algorism with improved distance].

    Science.gov (United States)

    Cai, Xianfa; Wei, Jia; Wen, Guihua; Li, Jie

    2011-12-01

    With its high dimensionalities, small samples and great noise, feature reduction of gene expression profile becomes quite necessary. The most common form of gene expression profile is nonlinear, and traditional dimensionality reduction methods can not project high dimensional data, whose initial dimensionalities are low, into low dimensional space. In this work, an improved distance locally linear embedding (LLE ) algorism was proposed to reduce the dimensionalities. LLE method is very sensitive to the closely-neighboring parameters. In order to enhance the robustness to the number of neighbors, in the paper we presented a novel distance to measure the distance between the samples for the purpose of reducing-the influence of distribution of samples. Experimental results demonstrated that the improved distance LLE can effectively extract information of classification features and greatly reduce the dimensionalities of data while maintaining a higher classification accuracy.

  1. Degraded Core Quench: Summary of Progress 1996-1999 - Executive Summary

    International Nuclear Information System (INIS)

    Haste, T.J.; Trambauer, K.

    2000-01-01

    models calibrated largely on the FZKA single rod data, and assessed the code against data from the same series. Development of KESS to include oxide cracking models is being continued, again using the FZKA data, and significant progress has been made. ICARE/CATHARE V1 was released in mid-1999, and testing of a shattering model based on that in SCDAP/RELAP5 is under way. Development is also under way for reflood/shattering models in MELCOR, while further assessment of the existing models in SCDAP/RELAP5 itself against the new FZKA bundle data is now in progress. The work so far shows an improvement in capability in that where there is a temperature increase and excess hydrogen production on quench (possible safety problem for the containment), this can be calculated, but to a lesser extent than that observed (therefore optimistic). Where there is no excursion, this is correctly simulated. This review has confined itself to the terms of reference of the original status report, thus not considering debris quench and other late phase matters. However it is noted that the experiments performed in the last two years have filled in gaps in knowledge at lower temperatures where the core would be in a mainly rod-like state. The LOFT LP-FP-2 experiment remains the only one (excluding TMI-2) performed with reflood from high temperatures where significant debris bed formation had occurred. Therefore, the possibility of conducting separate-effects experiments on quenching debris beds should be considered. Finally, the updating of the Degraded Core Code Validation Matrix which is now in progress should consider the new quench experiments, particularly with a view to including a QUENCH bundle test in the list of preferred experiments, when qualified, detailed data become freely available

  2. Locally noisy autonomous agents improve global human coordination in network experiments.

    Science.gov (United States)

    Shirado, Hirokazu; Christakis, Nicholas A

    2017-05-17

    Coordination in groups faces a sub-optimization problem and theory suggests that some randomness may help to achieve global optima. Here we performed experiments involving a networked colour coordination game in which groups of humans interacted with autonomous software agents (known as bots). Subjects (n = 4,000) were embedded in networks (n = 230) of 20 nodes, to which we sometimes added 3 bots. The bots were programmed with varying levels of behavioural randomness and different geodesic locations. We show that bots acting with small levels of random noise and placed in central locations meaningfully improve the collective performance of human groups, accelerating the median solution time by 55.6%. This is especially the case when the coordination problem is hard. Behavioural randomness worked not only by making the task of humans to whom the bots were connected easier, but also by affecting the gameplay of the humans among themselves and hence creating further cascades of benefit in global coordination in these heterogeneous systems.

  3. Surface defects control for ZnO nanorods synthesized by quenching and their anti-recombination in photocatalysis

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Jiawen [State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi’an 710072 (China); Fan, Huiqing, E-mail: hqfan3@163.com [State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi’an 710072 (China); Ma, Yuan [State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi’an 710072 (China); Wang, Zheng [Ministry of Education Key Laboratory of Contemporary Design and Integrated Manufacturing Technology, Northwestern Polytechnical University, Xi’an 710072 (China); Chang, Qi [State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi’an 710072 (China)

    2015-03-30

    Graphical abstract: - Highlights: • ZnO nanorods with controllable surface defects concentration were prepared by quenching treatment. • The recombination of photoinduced charges was greatly suppressed and controllable. • The electronic origin of light absorption enhancement was investigated. • Quenched ZnO showed excellent photocatalytic reactivity. - Abstract: ZnO nanorods with controllable surface defects was synthesized by high-temperature quenching method, and the recombination of photogenerated electron–hole pairs had been drastically suppressed, thus significantly improving the photocatalytic reactivity. The as-prepared samples were characterized for the surface structure, chemical state, phase structure as well as optical absorption using field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), Brunauer–Emmett–Teller (BET) analysis, X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), fluorescent spectrophotometer (PL), diffuse reflectance UV–visible spectroscopy (DRS) and zeta potential. With XPS valence band spectra characterization, its light absorption enhancement in UV–vis range was found due to induced additional electronic states above the valence band edge. Specific types of defects related to the quenching process were further investigated. Moreover, the concentration of surface defects and the recombination of carriers were controllable by quenching temperature, also affected by cooling rates. It provides a time-saving and straightforward method to suppressed recombination of photo-induced carriers and increased UV–vis light absorption for highly efficient ZnO-based photocatalyst applied to environmental remediation.

  4. Quench Tests of LHC Magnets with Beam: Studies on Beam Loss development and determination of Quench levels

    CERN Document Server

    Priebe, A; Sapinski, M

    The application of superconducting materials in the field of high energy accelerator physics not only opens the doors to the generation of the magnetic fields unattainable to normal conductors but also demands facing new challenges. A transition fromthe superconducting state, which is characterized by a resistance-free flow of the electric current, to the normal conducting state is called quenching. This process might be extremely dangerous and even lead to destruction of amagnet superconducting coil if no protecting actions are taken. Therefore, the knowledge of a magnet quench level, i.e. amount of energy which causes the transition to the resistive state, is crucial for the safety and operational efficiency of the accelerator. Regarding that, specific thresholds are incorporated to dedicated quench prevention systems in order to suppress the origin of detected energy perturbation, for example beam losses, or mitigate the consequences of the quenching process by dissipating the energy stored in the magnetic...

  5. [Quenched fluorescein: a reference dye for instrument response function of TCSPC].

    Science.gov (United States)

    Pan, Hai-feng; Ding, Jing-xin; Liang, Rong-rong; Tao, Zhan-dong; Liu, Meng-wei; Zhang, San-jun; Xu, Jian-hua

    2014-08-01

    Measuring the instrument response function (IRF) and fitting by reconvolution algorithms are routines to improve time resolution in fluorescence lifetime measurements. Iodide ions were successfully used to quench the fluorescence of fluorescein in this study. By systematically adding saturated NaI water solution in basic fluorescein solution, the lifetimes of fluorescein were reduced from 4 ns to 24 ps. The quenched lifetime of fluorescein obtained from the analysis of Time-Correlated Single Photon Counting (TCSPC) measurement agrees well with that from femtosecond frequency up-conversion measurement. In time resolved excitation spectra measurements, the IRF should be measured at various detection wavelengths providing scattring materials are used. This study could not only reduce the complexity of IRF measurement, but also avoid the existing color effect in system. This study should have wide applications in time resolved fluorescence spectroscopy and fluorescence lifetime imaging.

  6. Assessment of Bending Fatigue Strength of Crankshaft Sections with Consideration of Quenching Residual Stress

    Science.gov (United States)

    Qin, W. J.; Dong, C.; Li, X.

    2016-03-01

    High-cycle bending fatigue is the primary failure mode of crankshafts in engines. Compressive residual stresses are often introduced by induction quenching to improve the fatigue strength of crankshafts. The residual stresses, which are commonly obtained by numerical methods, such as the finite element method (FEM), should be included in fatigue failure analysis to predict the fatigue strength of crankshafts accurately. In this study, the simulation method and theory of quenching process are presented and applied to investigate the residual stresses of a diesel engine crankshaft. The coupling calculation of temperature, microstructure, and stress fields of the crankshaft section is conducted by FEM. Then, the fatigue strength of the crankshaft section is analytically assessed by Susmel and Lazzarin's criterion based on the critical plane approach that superimposes the residual stresses onto the bending stresses. The resonant bending fatigue tests of the crankshaft sections are conducted, and the tests and analytical assessments yield consistent results.

  7. Extrapedicular Infiltration Anesthesia as an Improved Method of Local Anesthesia for Unipedicular Percutaneous Vertebroplasty or Percutaneous Kyphoplasty

    Directory of Open Access Journals (Sweden)

    Liehua Liu

    2016-01-01

    Full Text Available Aim. This report introduces extrapedicular infiltration anesthesia as an improved method of local anesthesia for unipedicular percutaneous vertebroplasty or percutaneous kyphoplasty. Method. From March 2015 to March 2016, 44 patients (11 males and 33 females with osteoporotic vertebral compression fractures with a mean age of 71.4±8.8 years (range: 60 to 89 received percutaneous vertebroplasty or percutaneous kyphoplasty. 24 patients were managed with conventional local infiltration anesthesia (CLIA and 20 patients with both CLIA and extrapedicular infiltration anesthesia (EPIA. Patients evaluated intraoperative pain by means of the visual analogue score and were monitored during the procedure for additional sedative analgesia needs and for adverse nerve root effects. Results. VAS of CLIA + EPIA and CLIA group was 2.5±0.7 and 4.3±1.0, respectively, and there was significant difference (P=0.001. In CLIA group, 1 patient required additional sedative analgesia, but in CLIA + EPIA group, no patients required that. In the two groups, no adverse nerve root effects were noted. Summary. Extrapedicular infiltration anesthesia provided good local anesthetic effects without significant complications. This method deserves further consideration for use in unipedicular percutaneous vertebroplasty and percutaneous kyphoplasty.

  8. Extension of Local Disease in Nasopharyngeal Carcinoma Detected by Magnetic Resonance Imaging: Improvement of Clinical Target Volume Delineation

    International Nuclear Information System (INIS)

    Liang Shaobo; Sun Ying; Liu Lizhi; Chen Yong; Chen Lei; Mao Yanping; Tang Linglong; Tian Li; Lin Aihua; Liu Mengzhong; Li Li; Ma Jun

    2009-01-01

    Purpose: To define by MRI the local extension patterns in patients presenting with nasopharyngeal carcinoma (NPC) and to improve clinical target volume delineation. Methods and Materials: Consecutive patients (N = 943) with newly diagnosed and untreated NPC were included in this study. All patients underwent MRI of the nasopharynx and neck, which was reviewed by two radiologists. Results: According to the incidence rates of tumor invasion, the anatomic sites surrounding the nasopharynx were initially classified into three risk grades: high risk (≥ 35%), medium risk (≥ 5-35%), and low risk (< 5%). Incidence rates of tumor invasion into anatomic sites at medium risk were increased, reaching 55.2%, when adjacent high-risk anatomic sites were involved. However, the rates were substantially lower, mostly < 10%, when adjacent high-risk sites were not involved. The incidence rates of concurrent tumor invasion into bilateral sites were < 10%, except in the case of prevertebral muscle involvement (13.1%). Among the 178 incidences of cavernous sinus invasion, there were often two or more simultaneous infiltration routes (60.6%); when only one route was involved, the foramen ovale was the most common (26.4%). Conclusions: In patients presenting with NPC, local disease spreads stepwise from proximal sites to more distal sites. Tumors extend quickly through privileged pathways such as neural foramina. The anatomic sites surrounding the nasopharynx are at low risk of concurrent bilateral tumor invasion. Selective radiotherapy of the local disease in NPC may be feasible.

  9. Locally-Based Enterprise Training To Improve The Economic Empowerment Of The Learners Of Independent Enterprise Literacy

    Directory of Open Access Journals (Sweden)

    Dayat Hidayat

    2016-12-01

    Full Text Available Entrepreneurial skills of learners of Independent Enterprise Literacy at Community Learning Center (CLC Harapan Karawang Regency in developing locally-based enterprise, is still low. This study is aimed to analyze the planning, the implementation, the outcome, and the impact of locally-based enterprise training on improving the economic empowerment of the learners of Independent Enterprise Literacy. The approach uses in this study is a qualitative case study method. The subjects consist of four learners, a trainer, and an administrator of CLC. The data are obtained through the observation, in-depth interview, and documentation analysis. The data analysis involves the following stages: data collection, data reduction, data display, and conclusion drawing/verification. The locally-based enterprise training is designed through proper planning with the identification of learner needs, formulating objectives and preparing training curriculum that meets the needs and characteristics of the learners. The implementation of the training is conducted properly in accordance with a predetermined plan. The results of training assessment show an increase of knowledge, attitudes and behavior of learners’ entrepreneurial skills. The enterprise training gives impact and influence to increase the learners’ economic empowerment proved by the increasing income and wider business opportunities.

  10. Image guided adaptive brachytherapy with combined intracavitary and interstitial technique improves the therapeutic ratio in locally advanced cervical cancer: Analysis from the retroEMBRACE study

    DEFF Research Database (Denmark)

    LU, Fokdal; Sturdza, Alina; Mazeron, Renaud

    2016-01-01

    Background and purpose Image guided adaptive brachytherapy (IGABT) using intracavitary applicators (IC) has led to a significant improvement of local control in locally advanced cervical cancer (LACC). Further improvement has been obtained with combined intracavitary/interstitial (IC/IS) applicat......Background and purpose Image guided adaptive brachytherapy (IGABT) using intracavitary applicators (IC) has led to a significant improvement of local control in locally advanced cervical cancer (LACC). Further improvement has been obtained with combined intracavitary/interstitial (IC....../IS) applicators. The aim of this analysis was to evaluate the impact on local control and late morbidity of application of combined IS/IC brachytherapy in a large multicentre population. Material/methods 610 patients with LACC from the retroEMBRACE study were included. Patients were divided into an IC group (N...

  11. Improved dose localization with dual energy photon irradiation in treatment of lateralized intracranial malignancies

    International Nuclear Information System (INIS)

    Cooley, G.; Gillin, M.T.; Murray, K.J.; Wilson, J.F.; Janjan, N.A.

    1991-01-01

    Dual energy photon irradiation (6 MV and 20 MV) was compared to conventional treatment planning with 6 MV photons in a lateralized intracranial malignancy. Dose volume analysis was performed of both the tumor plus a 2 cm margin (target volume, TV) and normal tissues (NT). Parallel opposed treatment using weightings of 1:1, 1.5:1, and 2:1 were compared for 6 MV photons alone or in combination with 20 MV photons. Uniform treatment of the TV was accomplished within the 60 Gy isodose. Significant differences were observed, however, in NT volumes receiving greater than or equal to 60 Gy and 45-59 Gy. Dual photon energy reduced treatment of NT volumes to greater than or equal to 60 Gy by 13% (177 cm3 vs 204 cm3 in 2:1 weighting) to 70% (147 cm3 vs 498 cm3 in 1:1 weighting) for comparable plans. Dose optimization was also performed for both 6 MV alone or in combination with 20 MV photons. Usual approaches to achieve dose lateralization with conventional isocentric techniques were applied including parallel opposed 6 MV photons ipsilaterally weighted 3.4:1 (POP), and a 110 degrees arc rotational field used to limit treatment to the eye (ARC). Dual energy photon optimized plans included a three beam parallel opposed plan (TOP) and a mixed photon ipsilateral (IPSI) approach. The technique using parallel opposed 20 MV photons and ipsilateral 6 MV photons (TOP) used beam weightings of 1.1 (contralateral 20 MVX): 1.6 (ipsilateral 6 MVX): 1 (ipsilateral 20 MVX) to achieve dose optimization. The ipsilateral approach with 6 MVX and 20 MVX (IPSI) used beam weightings of 1:1.4, respectively. All optimized plans demonstrated a 41% (120 cm3; POP) to 53% (95 cm3; TOP) improvement over parallel opposed 6 MV photons weighted 2:1 (204 cm3) in NT volume receiving greater than or equal to 60 Gy

  12. Local O2 Balance in Cerebral Ischemia-Reperfusion Improved during Pentobarbital Compared with Isoflurane Anesthesia.

    Science.gov (United States)

    Chi, Oak Z; Barsoum, Sylviana; Rah, Kang H; Liu, Xia; Weiss, Harvey R

    2015-06-01

    Most anesthetics affect cerebral blood flow and metabolism. We compared microregional O2 balance in cerebral ischemia-reperfusion during pentobarbital and isoflurane anesthesia. After 1 hour of middle cerebral artery occlusion and a 2-hour reperfusion under isoflurane (1.4%, n = 14) or pentobarbital (50 mg/kg, n = 14) anesthesia in rats, regional cerebral blood flow using (14)C-iodoantipyrine autoradiography, microregional arterial and venous O2 saturation (20-60 μm in diameter) using cryomicrospectrophotometry, and the size of cortical infarct were determined. Ischemia-reperfusion decreased the average cortical venous O2 saturation in both pentobarbital and isoflurane groups (P pentobarbital despite a similar average regional cerebral blood flow and O2 consumption. The heterogeneity of venous O2 saturation reported as a coefficient of variation (100 × standard deviation/mean) was smaller (P pentobarbital than that with isoflurane (7.5 versus 16.1). The number of veins with low venous O2 saturation (pentobarbital (5 of 80 versus 24 of 80). The percentage of cortical infarct in total cortex was smaller with pentobarbital (5.2 ± 2.5% versus 12.3 ± 2.6%, P pentobarbital than isoflurane anesthesia. This improvement in microregional O2 balance with pentobarbital was accompanied by the reduced cortical infarct. Our data suggest that the neurologic outcome could vary during cerebral ischemia-reperfusion depending on the anesthetics used. Copyright © 2015 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  13. Final Technical Report: Intensive Quenching Technology for Heat Treating and Forging Industries

    Energy Technology Data Exchange (ETDEWEB)

    Aronov, Michael A.

    2005-12-21

    Intensive quenching (IQ) process is an alternative way of hardening (quenching) steel parts through the use of highly agitated water and then still air. It was developed by IQ Technologies, Inc. (IQT) of Akron, Ohio. While conventional quenching is usually performed in environmentally unfriendly oil or water/polymer solutions, the IQ process uses highly agitated environmentally friendly water or low concentration water/mineral salt solutions. The IQ method is characterized by extremely high cooling rates of steel parts. In contrast to conventional quenching, where parts cool down to the quenchant temperature and usually have tensile or neutral residual surface stresses at the end of quenching. The IQ process is interrupted when the part core is still hot and when there are maximum compressive stresses deep into the parts, thereby providing hard, ductile, better wear resistant parts. The project goal was to advance the patented IQ process from feasibility to commercialization in the heat-treating and forging industries to reduce significantly energy consumption and environmental impact, to increase productivity and to enhance economic competitiveness of these industries as well as Steel, Metal Casting and Mining industries. To introduce successfully the IQ technology in the U.S. metal working industry, the project team has completed the following work over the course of this project: A total of 33 manufacturers of steel products provided steel parts for IQ trails. IQT conducted IQ demonstrations for 34 different steel parts. Our customers tested intensively quenched parts in actual field conditions to evaluate the product service life and performance improvement. The data obtained from the field showed the following: Service life (number of holes punched) of cold-work punches (provided by EHT customer and made of S5 shock-resisting steel) was improved by two to eight times. Aluminum extrusion dies provided by GAM and made of hot work H-13 steel outperformed the

  14. A Study on Infrared Local Heat Treatment for AA5083 to Improve Formability and Automotive Part Forming

    Science.gov (United States)

    Lee, Eun-Ho; Yang, Dong-Yol; Ko, SeJin

    2017-10-01

    Automotive industries are increasingly employing aluminum alloys for auto parts to reduce vehicle weight. However, the low formability of aluminum alloys has been an obstacle to their application. To resolve the formability problem, some studies involving heat treatments under laboratory conditions have been reported. However, for industrial applications, the heat treatment sequence, heating energy efficiency, and a commercial part test should be studied. This work shows an infrared (IR) local heat treatment, heating only small areas where the heat treatment is required, for an aluminum alloy to improve the formability with a reduction of heating energy. The experiment shows that the formability drastically increases when the aluminum alloy is heat treated between two forming stages, referred to as intermediate heat treatment. The microstructures of the test pieces are evaluated to identify the cause of the increase in the formability. For an industrial application, an aluminum tailgate, which cannot be manufactured without heat treatment, was successfully manufactured by the IR local heat treatment with a reduction of energy. A simulation was also conducted with a stress-based forming limit diagram, which is not affected by the strain path and heat treatment histories. The simulation gives a good prediction of the formability improvement.

  15. High symptom improvement and local tumor control using stereotactic radiotherapy when given early after diagnosis of meningioma. A multicentre study

    Energy Technology Data Exchange (ETDEWEB)

    Compter, I.; Houben, R.M.A.; Bosmans, G.; Baumert, B.G. [Maastricht Univ. Medical Centre (Netherlands). Dept. of Radiation-Oncology (MAASTRO); Zaugg, K.; Buescher, C. [University Hospital Zurich (Switzerland). Clinic and Policlinic of Radiation-Oncology; Dings, J.T.A. [Maastricht Univ. Medical Centre (Netherlands). Dept. of Neurosurgery; Anten, M.M.H.M.E. [Maastricht Univ. Medical Centre (Netherlands). Dept. of Neurology

    2012-10-15

    Purpose: The goal of the present study was to analyze long-term results of fractionated stereotactic radiotherapy (SRT) in patients with a meningioma. Methods and materials: A total of 72 patients treated between 1996 and 2008 in MAASTRO clinic (n = 45) and University Hospital Zurich (n = 27) were included. SRT was given as primary treatment (n = 46), postoperatively (n = 19) or at recurrence (n = 7); 49 tumours (68%) were located in the skull base. Median total dose was 54 Gy. Results: Median follow-up was 4.13 years (range 0.66-11 years). The 3- and 5-year overall survival were 92 and 79% for grade 0 and I meningioma. Progression-free survival for grade 0 and I was 95% at 3 and 5 years, and 40% for grade II and III at 3 years. In 98.4% of patients, clinical symptoms were stable or improved. The majority of symptoms improved within 24 months after SRT. Local control is significantly better if patients are irradiated immediately after diagnosis compared to a watchful waiting policy (p = 0.017). Grade IV toxicity was low (4.2%, n = 3) Conclusion: SRT is an effective treatment with high local and clinical control. Early SRT resulted in better outcome than late treatment at progression. (orig.)

  16. Tracing Improving Livelihoods in Rural Africa Using Local Measures of Wealth: A Case Study from Central Tanzania, 1991–2016

    Directory of Open Access Journals (Sweden)

    Wilhelm Östberg

    2018-04-01

    Full Text Available We studied livelihood changes and poverty dynamics over a 25-year period in two villages in central Tanzania. The villages were, from the early 1990s and 2000s, strikingly poor with between 50% and 55% of families in the poorest wealth groups. 25 years later much has changed: people have become substantially wealthier, with 64% and 71% in the middle wealth groups. The new wealth had been generated locally, from farming, particularly of sunflowers as a cash crop. This goes against a conventional view of small-scale farming in Tanzania as being stagnant or unproductive. The area of land farmed per family has increased, almost doubling in one village. People have made money, which they invest in mechanised farming, improved housing, education of their children, livestock, and consumer goods. Improved infrastructure and local entrepreneurs have played key roles in the area’s transformation. Locally identified wealth rankings showed that most villagers, those in the middle wealth groups and above, can now support themselves from their land, which is a notable change to a time when 71% and 82% in each village respectively depended on casual labour for their survival. This change has come at a cost to the environment. By 2016, the village forests have largely gone and been replaced by farms. Farmers were concerned that the climate was turning drier because of deforestation. Studying the mundane—the material used in roofs, the size of farms, and so on made it possible to trace and understand the radical transition the area has experienced.

  17. IMPACT OF IMPROVED SEEDS ON SMALL FARMERS' PRODUCTIVITY, INCOME AND LIVELIHOOD OF BARA LOCALITY IN NORTH KORDOFAN STATE, SUDAN

    Directory of Open Access Journals (Sweden)

    Elkhalil Elnour Briema Ahmed

    2013-08-01

    Full Text Available This study was designed to test and identify the impact of improved seeds on small farmers' productivity, income and livelihood in Bara locality. Sixty households participants were randomly selected through a field survey during 2011 for 2008/2009, 2009/2010 and 2010/2011 cropping seasons. The study applied Multi-stage random sample technique. Based on existing farm situation and price level, the sampled farmers were obtained SDG 8604 as gross margin to cover all expenses. Results of this study also depicted that the required net income and off-farm income were 16293 and 11378 SDG, respectively. With respect to Linear Programming (LP results, a total of SDG 8890 were obtained and all crops were entered and solved. The optimal plan and existing farm situation were changed by 3.3 and 5.6% for gross margin and cash income, respectively. Results of LP also indicated a positive change in production patterns of resource use; 3.3, 6.2, 3.5, 3.3 and 9.1% for land, cash income, labour, seeds supply and productivity, respectively under existing and optimal plan. Partial crop budgeting revealed that, all treatments were financially gave positive returns. Dominance analysis showed that cowpea ainelgazal, okra, roselle and sesame herhri crops were dominated by crops of millet ashana, watermelon, groundnut and guar, respectively. Marginal analysis exposed that, for every SDG 1.00 invested in improved seeds cultivation, farmer can expect to cover the SDG 1.00 and obtain an additional SDG 1.345; then, additional seed rate implies a further marginal rate of SDG 43.9. Sensitivity analysis for cost over run and benefit reduction by 10% indicated highly stability with MRR of 1.22, 3.991 and 1.21 and 3.951% for watermelon and guar, respectively. The productivity of improved seeds compared to local ones was increased in some varieties and decreased among others. This study reached to some recommendations for improving crop productivity, production and livelihood of

  18. Evaluation of Local Vegetable Oils as Quenchants for Hardening ...

    African Journals Online (AJOL)

    However, the wear resistance of the quenched grey cast iron developed in this group of local vegetable oils was superior to that of SAE40 engine oil. The potentials of these oils as quenching media for grey cast iron hardening process ranked in descending order as soya bean, shea butter, groundnut, and palm kernel, with ...

  19. Characterization of oil based nanofluid for quench medium

    Science.gov (United States)

    Mahiswara, E. P.; Harjanto, S.; Putra, W. N.; Ramahdita, G.; Yahya, S. S.; Kresnodrianto

    2018-01-01

    The choice of quench medium depends on the hardenability of the metal alloy, the thickness of the component, and the geometry of the component. Some of these will determine the cooling rate required to obtain the desired microstructure and material properties. Improper quench media will cause the material to become brittle, suffers from geometric distortion, or having a high undesirable residual stresses in the components. In heat treatment industries, oil and water are frequently used as the quench media. Recently, nanofluid as a quench medium has also been studied using several different fluids as the solvent. Examples of frequently used solvents include polymers, vegetable oils, and mineral oil. In this research, laboratory-grade carbon powder were used as nanoparticle. Oil was used as the fluid base in this research as the main observation focus. To obtain nanoscale carbon particles, planetary ball mill was used to ground laboratory grade carbon powder to decrease the particle size. This method was used to lower the cost for nanoparticle synthesis. Milling speed and duration were set at 500 rpm and 15 hours. Field Emission Scanning Electron Microscope (FE-SEM), and Energy Dispersive X-Ray (EDX) measurement were carried out to determine the particle size, material identification, particle morphology, and surface change of samples. The carbon nanoparticle content in nanofluid quench mediums for this research were varied at 0.1%, 0.2%, 0.3%, 0.4, and 0.5 % volume. Furthermore, these mediums were used to quench JIS S45C or AISI 1045 carbon steel samples which annealed at 1000°C. Hardness testing and metallography observation were then conducted to further examine the effect of different quench medium in steel samples.

  20. Dust emission from wet, low-emission coke quenching process

    Science.gov (United States)

    Komosiński, Bogusław; Bobik, Bartłomiej; Konieczny, Tomasz; Cieślik, Ewelina

    2018-01-01

    Coke plants, which produce various types of coke (metallurgical, foundry or heating), at temperatures between 600 and 1200°C, with limited access to oxygen, are major emitters of particulates and gaseous pollutants to air, water and soils. Primarily, the process of wet quenching should be mentioned, as one of the most cumbersome. Atmospheric pollutants include particulates, tar substances, organic pollutants including B(a)P and many others. Pollutants are also formed from the decomposition of water used to quench coke (CO, phenol, HCN, H2S, NH3, cresol) and decomposition of hot coke in the first phase of quenching (CO, H2S, SO2) [1]. The development of the coke oven technology has resulted in the changes made to different types of technological installations, such as the use of baffles in quench towers, the removal of nitrogen oxides by selective NOx reduction, and the introduction of fabric filters for particulates removal. The BAT conclusions for coke plants [2] provide a methodology for the measurement of particulate emission from a wet, low-emission technology using Mohrhauer probes. The conclusions define the emission level for wet quenching process as 25 g/Mgcoke. The conducted research was aimed at verification of the presented method. For two of three quench towers (A and C) the requirements included in the BAT conclusions are not met and emissions amount to 87.34 and 61.35 g/Mgcoke respectively. The lowest particulates emission was recorded on the quench tower B and amounted to 22.5 g/Mgcoke, therefore not exceeding the requirements.

  1. Dust emission from wet, low-emission coke quenching process

    Directory of Open Access Journals (Sweden)

    Komosiński Bogusław

    2018-01-01

    Full Text Available Coke plants, which produce various types of coke (metallurgical, foundry or heating, at temperatures between 600 and 1200°C, with limited access to oxygen, are major emitters of particulates and gaseous pollutants to air, water and soils. Primarily, the process of wet quenching should be mentioned, as one of the most cumbersome. Atmospheric pollutants include particulates, tar substances, organic pollutants including B(aP and many others. Pollutants are also formed from the decomposition of water used to quench coke (CO, phenol, HCN, H2S, NH3, cresol and decomposition of hot coke in the first phase of quenching (CO, H2S, SO2 [1]. The development of the coke oven technology has resulted in the changes made to different types of technological installations, such as the use of baffles in quench towers, the removal of nitrogen oxides by selective NOx reduction, and the introduction of fabric filters for particulates removal. The BAT conclusions for coke plants [2] provide a methodology for the measurement of particulate emission from a wet, low-emission technology using Mohrhauer probes. The conclusions define the emission level for wet quenching process as 25 g/Mgcoke. The conducted research was aimed at verification of the presented method. For two of three quench towers (A and C the requirements included in the BAT conclusions are not met and emissions amount to 87.34 and 61.35 g/Mgcoke respectively. The lowest particulates emission was recorded on the quench tower B and amounted to 22.5 g/Mgcoke, therefore not exceeding the requirements.

  2. Quantum quenches in disordered systems: approach to thermal equilibrium without a typical relaxation time.

    Science.gov (United States)

    Khatami, Ehsan; Rigol, Marcos; Relaño, Armando; García-García, Antonio M

    2012-05-01

    We study spectral properties and the dynamics after a quench of one-dimensional spinless fermions with short-range interactions and long-range random hopping. We show that a sufficiently fast decay of the hopping term promotes localization effects at finite temperature, which prevents thermalization even if the classical motion is chaotic. For slower decays, we find that thermalization does occur. However, within this model, the latter regime falls in an unexpected universality class, namely, observables exhibit a power-law (as opposed to an exponential) approach to their thermal expectation values.

  3. Improved Biochemical Outcomes With Statin Use in Patients With High-Risk Localized Prostate Cancer Treated With Radiotherapy

    International Nuclear Information System (INIS)

    Kollmeier, Marisa A.; Katz, Matthew S.; Mak, Kimberley; Yamada, Yoshiya; Feder, David J.; Zhang Zhigang; Jia Xiaoyu; Shi Weiji; Zelefsky, Michael J.

    2011-01-01

    Purpose: To investigate the association between 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) and biochemical and survival outcomes after high-dose radiotherapy (RT) for prostate cancer. Methods and Materials: A total of 1711 men with clinical stage T1-T3 prostate cancer were treated with conformal RT to a median dose of 81 Gy during 1995-2007. Preradiotherapy medication data were available for 1681 patients. Three hundred eighty-two patients (23%) were taking a statin medication at diagnosis and throughout RT. Nine hundred forty-seven patients received a short-course of neoadjuvant and concurrent androgen-deprivation therapy (ADT) with RT. The median follow-up was 5.9 years. Results: The 5- and 8-year PSA relapse-free survival (PRFS) rates for statin patients were 89% and 80%, compared with 83% and 74% for those not taking statins (p = 0.002). In a multivariate analysis, statin use (hazard ratio [HR] 0.69, p = 0.03), National Comprehensive Cancer Network (NCCN) low-risk group, and ADT use were associated with improved PRFS. Only high-risk patients in the statin group demonstrated improvement in PRFS (HR 0.52, p = 0.02). Across all groups, statin use was not associated with improved distant metastasis-free survival (DMFS) (p = 0.51). On multivariate analysis, lower NCCN risk group (p = 0.01) and ADT use (p = 0.005) predicted improved DMFS. Conclusions: Statin use during high-dose RT for clinically localized prostate cancer was associated with a significant improvement in PRFS in high-risk patients. These data suggest that statins have anticancer activity and possibly provide radiosensitization when used in conjunction with RT in the treatment of prostate cancer.

  4. Improving quantitative precipitation nowcasting with a local ensemble transform Kalman filter radar data assimilation system: observing system simulation experiments

    Directory of Open Access Journals (Sweden)

    Chih-Chien Tsai

    2014-03-01

    Full Text Available This study develops a Doppler radar data assimilation system, which couples the local ensemble transform Kalman filter with the Weather Research and Forecasting model. The benefits of this system to quantitative precipitation nowcasting (QPN are evaluated with observing system simulation experiments on Typhoon Morakot (2009, which brought record-breaking rainfall and extensive damage to central and southern Taiwan. The results indicate that the assimilation of radial velocity and reflectivity observations improves the three-dimensional winds and rain-mixing ratio most significantly because of the direct relations in the observation operator. The patterns of spiral rainbands become more consistent between different ensemble members after radar data assimilation. The rainfall intensity and distribution during the 6-hour deterministic nowcast are also improved, especially for the first 3 hours. The nowcasts with and without radar data assimilation have similar evolution trends driven by synoptic-scale conditions. Furthermore, we carry out a series of sensitivity experiments to develop proper assimilation strategies, in which a mixed localisation method is proposed for the first time and found to give further QPN improvement in this typhoon case.

  5. Topology-corrected segmentation and local intensity estimates for improved partial volume classification of brain cortex in MRI.

    Science.gov (United States)

    Rueda, Andrea; Acosta, Oscar; Couprie, Michel; Bourgeat, Pierrick; Fripp, Jurgen; Dowson, Nicholas; Romero, Eduardo; Salvado, Olivier

    2010-05-15

    In magnetic resonance imaging (MRI), accuracy and precision with which brain structures may be quantified are frequently affected by the partial volume (PV) effect. PV is due to the limited spatial resolution of MRI compared to the size of anatomical structures. Accurate classification of mixed voxels and correct estimation of the proportion of each pure tissue (fractional content) may help to increase the precision of cortical thickness estimation in regions where this measure is particularly difficult, such as deep sulci. The contribution of this work is twofold: on the one hand, we propose a new method to label voxels and compute tissue fractional content, integrating a mechanism for detecting sulci with topology preserving operators. On the other hand, we improve the computation of the fractional content of mixed voxels using local estimation of pure tissue intensity means. Accuracy and precision were assessed using simulated and real MR data and comparison with other existing approaches demonstrated the benefits of our method. Significant improvements in gray matter (GM) classification and cortical thickness estimation were brought by the topology correction. The fractional content root mean squared error diminished by 6.3% (pexpert segmentations, the similarity measure was improved by 12.0% (p<0.001). Thickness estimation with the proposed method showed a higher reproducibility compared with the measure performed after partial volume classification using other methods. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  6. Improving Signal-to-Noise Ratio in Susceptibility Weighted Imaging: A Novel Multicomponent Non-Local Approach.

    Directory of Open Access Journals (Sweden)

    Pasquale Borrelli

    Full Text Available In susceptibility-weighted imaging (SWI, the high resolution required to obtain a proper contrast generation leads to a reduced signal-to-noise ratio (SNR. The application of a denoising filter to produce images with higher SNR and still preserve small structures from excessive blurring is therefore extremely desirable. However, as the distributions of magnitude and phase noise may introduce biases during image restoration, the application of a denoising filter is non-trivial. Taking advantage of the potential multispectral nature of MR images, a multicomponent approach using a Non-Local Means (MNLM denoising filter may perform better than a component-by-component image restoration method. Here we present a new MNLM-based method (Multicomponent-Imaginary-Real-SWI, hereafter MIR-SWI to produce SWI images with high SNR and improved conspicuity. Both qualitative and quantitative comparisons of MIR-SWI with the original SWI scheme and previously proposed SWI restoring pipelines showed that MIR-SWI fared consistently better than the other approaches. Noise removal with MIR-SWI also provided improvement in contrast-to-noise ratio (CNR and vessel conspicuity at higher factors of phase mask multiplications than the one suggested in the literature for SWI vessel imaging. We conclude that a proper handling of noise in the complex MR dataset may lead to improved image quality for SWI data.

  7. Lessons learned from the quench-11 training exercise

    International Nuclear Information System (INIS)

    Hohorst, J.K.; Allison, C.M.

    2007-01-01

    16 organizations in 12 countries are participating in a RELAP/SCDAPSIM training exercise based on the Quench 11 experiment performed at Karlsruhe (Germany) in 2005. This exercise is being conducted in parallel to an International Standard Problem (ISP). Both the ISP and the RELAP/SCDAPSIM training exercise included a 'semi-blind' portion that was completed in the fall of 2006 and an 'open' portion that is to be completed in the summer of 2007. The RELAP/SCDAPSIM training exercise is coordinated by Innovative Systems Software with support by the International SCDAP Development and Training Program (SDTP). The Quench-11 experiment is based on an electrically heated fuel rod bundle representative of a PWR design. The bundle was subjected to a boil down transient, heat-up, and quenching with peak temperatures exceeding the melting point of the Zircaloy cladding. This experiment was chosen by the European Union as an International Benchmark exercise to compare the effectiveness of quenching models in the severe accident computer codes used today for accident analysis. This paper briefly describes (a) RELAP/SCDAPSIM/MOD3.4, (b) the Quench facility and experiments used in the training exercise, and (c) the training guidelines provided to the participants followed by a more detailed description of the lessons learned from the initial 'semi-blind' portion. The representative results demonstrate that good analysts can still have a difficult time predicting the thermal hydraulic response of a relative simple transient in a complex system

  8. Singlet oxygen quenching by oxygen in tetraphenyl-porphyrin solutions

    International Nuclear Information System (INIS)

    Dedic, Roman; Korinek, Miloslav; Molnar, Alexander; Svoboda, Antonin; Hala, Jan

    2006-01-01

    Time-resolved measurement of singlet oxygen infrared phosphorescence is a powerful tool for determination of quantum yields and kinetics of its photosensitization. This technique was employed to investigate in detail the previously observed effect of singlet oxygen quenching by oxygen. The question whether the singlet oxygen is quenched by oxygen in ground or in excited state was addressed by study of two complementary dependencies of singlet oxygen lifetimes: on dissolved oxygen concentration and on excitation intensity. Oxygen concentration dependence study of meso-tetra(4-sulphonato)phenylporphyrin (TPPS 4 ) phosphorescence kinetics showed linearity of the dependence of TPPS 4 triplet state rate-constant. Corresponding bimolecular quenching constant of (1.5±0.1)x10 9 l/mol s was obtained. On the other hand, rate constants of singlet oxygen depopulation exhibit nonlinear dependence on oxygen concentration. Comparison of zero oxygen concentration-extrapolated value of singlet oxygen lifetime of (6.5±0.4) μs to (3.7±0.1) μs observed under air-saturated conditions indicates importance of the effect of quenching of singlet oxygen by oxygen. Upward-sloping dependencies of singlet oxygen depopulation rate-constant on excitation intensity evidence that singlet oxygen is predominantly quenched by oxygen in excited singlet state

  9. Effects of β phase quenching on the corrosion resistance of Zircaloy-4

    International Nuclear Information System (INIS)

    Zhou Bangxin; Li Qiang

    2000-01-01

    The microstructure and corrosion resistance of Zircaloy-4 after β quenching or reheated at 700 degree C-1h have been investigated. Fine martensites with high dislocation density were obtained after β phase quenching. There was no second phase particles precipitated, but some residual β-Zr (crystal lattice a = 0.355 nm) could be detected. This kinds of microstructure possesses very poor corrosion resistance, and white or grey oxide films are easy to form even if autoclave tests in 400 degree C superheated steam after 45 days. After β phase quenching and reheated at 700 degree C-1h , two kinds of microstructure were observed. One is coarse martensites formed through the migration of grain boundaries, and second phase particles of Zr(Fe, Cr) 2 precipitated on grain boundaries. The density of dislocation is also reduced remarkably. The corrosion resistance of this kind of microstructure is improved considerably to form black oxide films on the surface. The other is equal-axis coarse grains through the abnormal grain growth after recrystallization, the diameter of grains reaches 0.2-0.5 mm. The nodular corrosion resistance of this kinds of microstructure is very poor, and the nodules formed during the autoclave tests in 400 degree C superheated steam after 45 days

  10. Quenching measurements and modeling of a boron-loaded organic liquid scintillator

    Energy Technology Data Exchange (ETDEWEB)

    Westerdale, S.; Xu, J.; Shields, E.; Froborg, F.; Calaprice, F.; Alexander, T.; Aprahamian, A.; Back, H. O.; Casarella, C.; Fang, X.; Gupta, Y. K.; Lamere, E.; Liu, Q.; Lyons, S.; Smith, M.; Tan, W.

    2017-08-01

    Organic liquid scintillators are used in a wide variety of applications in experimental nuclear and particle physics. Boron-loaded scintillators are particularly useful for detecting neutron captures, due to the high thermal neutron capture cross section of $^{10}$B. These scintillators are commonly used in neutron detectors, including the DarkSide-50 neutron veto, where the neutron may produce a signal when it scatters off protons in the scintillator or when it captures on $^{10}$B. Reconstructing the energy of these recoils is complicated by scintillation quenching. Understanding how nuclear recoils are quenched in these scintillators is an important and difficult problem. In this article, we present a set of measurements of neutron-induced proton recoils in a boron-loaded organic liquid scintillator at recoil energies ranging from 57--467 keV, and we compare these measurements to predictions from different quenching models. We find that a modified Birks' model whose denominator is quadratic in $dE/dx$ best describes the measurements, with $\\chi^2$/NDF$=1.6$. This result will help model nuclear recoil scintillation in similar detectors and can be used to improve their neutron tagging efficiency.

  11. Evaluation of QUENCH 12 test with ASTEC1.3R2 computer code

    International Nuclear Information System (INIS)

    Stefanova, A.; Groudev, P.

    2009-01-01

    This paper presents an assessment of QUENCH 12 test with ASTEC1.3R2 computer code. The test was performed to investigate the behavior of VVER fuel assemblies with a hexagonal lattice and containing fuel rod claddings made of Zrl%Nb(E 110) as used in eastern VVER reactors. The fuel is represented by ZrO 2 pellets. This investigation is a part of the 6-th framework program of the European Community supported ISTC program. The test facility is located at Forschungszentrum in Karlsruhe. The structure of the test facility allows experimental studies under transient and accident conditions. The purpose of QUENCH experiments is to investigate the hydrogen source term resulting from the water or steam injection into an uncovered degraded core of a Light-Water Reactor (LWR), to examine the behavior of overheated fuel elements under different flooding conditions, and to create a data base for model development and improvement of Severe Fuel Damage code packages. The ASTEC1.3R2 computer codes have been used to simulate the investigated transient. The base line input model for ASTEC was provided from Forschungszentrum, Karlsruhe. During the preparation of QUENCH 12 test, the input deck was adapted to new initial and boundary conditions. The new geometry of VVER bundle, grid spacer and corner rods was corrected. The comparison show very good agreement between measured data and ASTEC results. (authors)

  12. The Effectiveness of Reengineering Moheb Project to Improve Knowledge, Attitude, and Performance of Individuals & Local Communities in Response to Earthquake: A Case Study

    Directory of Open Access Journals (Sweden)

    Hamidreza Eskash

    2016-07-01

    Conclusion: Regarding the fact that knowledge, attitude, and performance of the people at local communities about earthquake were improved, the interventional programs, especially educational and promotional plan, can effectively empower individuals to face disasters.

  13. Decreased repopulation as well as increased reoxygenation contribute to the improvement in local control after targeting of the EGFR by C225 during fractionated irradiation.

    NARCIS (Netherlands)

    Krause, M.; Ostermann, G.; Petersen, C.; Yaromina, A.; Hessel, F.; Harstrick, A.; Kogel, A.J. van der; Thames, H.D.; Baumann, M.

    2005-01-01

    BACKGROUND AND PURPOSE: Inhibition of repopulation and enhanced reoxygenation has been suggested to contribute to improvement of local tumour control after fractionated irradiation combined with inhibitors of the epidermal growth factor receptor (EGFR). The present study addresses this hypothesis in

  14. What can local authorities do to improve the social care-related quality of life of older adults living at home? Evidence from the Adult Social Care Survey

    NARCIS (Netherlands)

    van Leeuwen, K.M.; Malley, J.; Bosmans, J.E.; Jansen, A.P.D.; Ostelo, R.W.J.G.; van der Horst, H.E.; Netten, A.

    2014-01-01

    Local authorities spend considerable resources on social care at home for older adults. Given the expected growth in the population of older adults and budget cuts on local government, it is important to find efficient ways of maintaining and improving the quality of life of older adults. The ageing

  15. What can local authorities do to improve the social care-related quality of life of older adults living at home? : Evidence from the Adult Social Care Survey

    NARCIS (Netherlands)

    van Leeuwen, K M; Malley, J; Bosmans, J E; Jansen, A P D; Ostelo, R W; van der Horst, H E; Netten, A

    Local authorities spend considerable resources on social care at home for older adults. Given the expected growth in the population of older adults and budget cuts on local government, it is important to find efficient ways of maintaining and improving the quality of life of older adults. The ageing

  16. Spectral analysis of colour-quenched and chemically quenched C-14 samples; Estudio espectral de muestras de C-14 con extincion quimica y por color en centelleo liquido

    Energy Technology Data Exchange (ETDEWEB)

    Scott, P. E.; Grau, A.

    1987-07-01

    In this paper pairs of pulse height distribution curves, of C-14 samples, colour-quenched and chemically quenched was obtained. The possibility to choose a counting window in order to obtain the counting efficiency curves, for both type of quenching was studied. (Author) 7 refs.

  17. The Accuracy of ADC Measurements in Liver Is Improved by a Tailored and Computationally Efficient Local-Rigid Registration Algorithm.

    Science.gov (United States)

    Ragheb, Hossein; Thacker, Neil A; Guyader, Jean-Marie; Klein, Stefan; deSouza, Nandita M; Jackson, Alan

    2015-01-01

    This study describes post-processing methodologies to reduce the effects of physiological motion in measurements of apparent diffusion coefficient (ADC) in the liver. The aims of the study are to improve the accuracy of ADC measurements in liver disease to support quantitative clinical characterisation and reduce the number of patients required for sequential studies of disease progression and therapeutic effects. Two motion correction methods are compared, one based on non-rigid registration (NRA) using freely available open source algorithms and the other a local-rigid registration (LRA) specifically designed for use with diffusion weighted magnetic resonance (DW-MR) data. Performance of these methods is evaluated using metrics computed from regional ADC histograms on abdominal image slices from healthy volunteers. While the non-rigid registration method has the advantages of being applicable on the whole volume and in a fully automatic fashion, the local-rigid registration method is faster while maintaining the integrity of the biological structures essential for analysis of tissue heterogeneity. Our findings also indicate that the averaging commonly applied to DW-MR images as part of the acquisition protocol should be avoided if possible.

  18. Wet cupping therapy improves local blood perfusion and analgesic effects in patients with nerve-root type cervical spondylosis.

    Science.gov (United States)

    Meng, Xiang-Wen; Wang, Ying; Piao, Sheng-Ai; Lv, Wen-Tao; Zhu, Cheng-Hui; Mu, Ming-Yuan; Li, Dan-Dan; Liu, Hua-Peng; Guo, Yi

    2018-01-15

    To observe wet cupping therapy (WCT) on local blood perfusion and analgesic effects in patients with nerve-root type cervical spondylosis (NT-CS). Fifty-seven NT-CS patients were randomly divided into WCT group and Jiaji acupoint-acupuncture (JA) group according a random number table. WCT group (30 cases) was treated with WCT for 10 min, and JA group (27 cases) was treated with acupuncture for 10 min. The treatment effificacies were evaluated with a Visual Analogue Scale (VAS). Blood perfusion at Dazhui (GV 14) and Jianjing (GB 21) acupoints (affected side) was observed with a laser speckle flflowmetry, and its variations before and after treatment in both groups were compared as well. In both groups, the VAS scores signifificantly decreased after the intervention (P<0.01), while the blood perfusion at the two acupoints signifificantly increased after intervention (P<0.05); however, the increasement magnitude caused by WCT was obvious compared with JA (P<0.05). WCT could improve analgesic effects in patients with NT-CS, which might be related to increasing local blood perfusion of acupunct points.

  19. Improvements in localized proton NMR spectroscopy of human brain. Water suppression, short echo times, and 1 ml resolution

    Science.gov (United States)

    Frahm, J.; Michaelis, T.; Merboldt, K. D.; Bruhn, H.; Gyngell, M. L.; Hänicke, W.

    Considerable technical improvements are reported for localized proton NMR spectroscopy using stimulated echoes. When compared to previous results, proton NMR spectra of the human brain are now obtainable (i) with in vivo water suppression factors of ⩾1000, (ii) with only minor T2 losses and negligible distortions due to J modulation at short echo times of 10-20 ms, and (iii) from volumes of interest as small as 1-8 ml within measuring times of 1-10 min. As a consequence, the detection of cerebral metabolites is greatly facilitated. This particularly applies to the assignment of those resonances (e.g., glutamate, taurine, inositols) that suffer from strong spin-spin coupling at the field strengths commonly in use for NMR in man. Studies of regional metabolite differences, tissue heterogeneity, and focal lesions in patients benefit from the increased spatial resolution and a concomitant reduction of partial volume effects. Localized proton NMR spectroscopy was performed on young healthy volunteers. Experiments were carried out on a 2.0 T whole-body MRI/MRS system using the standard headcoil for both imaging and spectroscopy.

  20. Multiphysics and Thermal Response Models to Improve Accuracy of Local Temperature Estimation in Rat Cortex under Microwave Exposure

    Directory of Open Access Journals (Sweden)

    Sachiko Kodera

    2017-03-01

    Full Text Available The rapid development of wireless technology has led to widespread concerns regarding adverse human health effects caused by exposure to electromagnetic fields. Temperature elevation in biological bodies is an important factor that can adversely affect health. A thermophysiological model is desired to quantify microwave (MW induced temperature elevations. In this study, parameters related to thermophysiological responses for MW exposures were estimated using an electromagnetic-thermodynamics simulation technique. To the authors’ knowledge, this is the first study in which parameters related to regional cerebral blood flow in a rat model were extracted at a high degree of accuracy through experimental measurements for localized MW exposure at frequencies exceeding 6 GHz. The findings indicate that the improved modeling parameters yield computed results that match well with the measured quantities during and after exposure in rats. It is expected that the computational model will be helpful in estimating the temperature elevation in the rat brain at multiple observation points (that are difficult to measure simultaneously and in explaining the physiological changes in the local cortex region.