WorldWideScience

Sample records for impact declarative terms

  1. The impact of levodopa on non-declarative and declarative learning

    OpenAIRE

    Fuhrer, Hannah

    2015-01-01

    We aim to assess the role of levodopa in non-declarative and declarative learning. Patients with Parkinson’s disease are known to suffer from striatal dopamine depletion and to be impaired in non- declarative memory tasks. We therefore hypothesized that the intake of levodopa may improve non- declarative learning. Furthermore, as declarative memory is represented in medial temporal lobe structures, we anticipated patients with Parkinson’s disease not to be impaired in declarative tests. We st...

  2. The Impact of the Universal Declaration of Human Rights on the Study of History

    NARCIS (Netherlands)

    De Baets, Antoon

    There is perhaps no text with a broader impact on our lives than the 1948 Universal Declaration of Human Rights (UDHR). It is strange, therefore, that historians have paid so little attention to the UDHR. I argue that its potential impact on the study of history is profound. After asking whether the

  3. Temporal lobe surgery in childhood and neuroanatomical predictors of long-term declarative memory outcome

    Science.gov (United States)

    Skirrow, Caroline; Cross, J. Helen; Harrison, Sue; Cormack, Francesca; Harkness, William; Coleman, Rosie; Meierotto, Ellen; Gaiottino, Johanna; Vargha-Khadem, Faraneh

    2015-01-01

    The temporal lobes play a prominent role in declarative memory function, including episodic memory (memory for events) and semantic memory (memory for facts and concepts). Surgical resection for medication-resistant and well-localized temporal lobe epilepsy has good prognosis for seizure freedom, but is linked to memory difficulties in adults, especially when the removal is on the left side. Children may benefit most from surgery, because brain plasticity may facilitate post-surgical reorganization, and seizure cessation may promote cognitive development. However, the long-term impact of this intervention in children is not known. We examined memory function in 53 children (25 males, 28 females) who were evaluated for epilepsy surgery: 42 underwent unilateral temporal lobe resections (25 left, 17 right, mean age at surgery 13.8 years), 11 were treated only pharmacologically. Average follow-up was 9 years (range 5–15). Post-surgical change in visual and verbal episodic memory, and semantic memory at follow-up were examined. Pre- and post-surgical T1-weighted MRI brain scans were analysed to extract hippocampal and resection volumes, and evaluate post-surgical temporal lobe integrity. Language lateralization indices were derived from functional magnetic resonance imaging. There were no significant pre- to postoperative decrements in memory associated with surgery. In contrast, gains in verbal episodic memory were seen after right temporal lobe surgery, and visual episodic memory improved after left temporal lobe surgery, indicating a functional release in the unoperated temporal lobe after seizure reduction or cessation. Pre- to post-surgical change in memory function was not associated with any indices of brain structure derived from MRI. However, better verbal memory at follow-up was linked to greater post-surgical residual hippocampal volumes, most robustly in left surgical participants. Better semantic memory at follow-up was associated with smaller resection

  4. Long-term consolidation of declarative memory: insight from temporal lobe epilepsy.

    Science.gov (United States)

    Tramoni, Eve; Felician, Olivier; Barbeau, Emmanuel J; Guedj, Eric; Guye, Maxime; Bartolomei, Fabrice; Ceccaldi, Mathieu

    2011-03-01

    Several experiments carried out with a subset of patients with temporal lobe epilepsy have demonstrated normal memory performance at standard delays of recall (i.e. minutes to hours) but impaired performance over longer delays (i.e. days or weeks), suggesting altered long-term consolidation mechanisms. These mechanisms were specifically investigated in a group of five adult-onset pharmaco-sensitive patients with temporal lobe epilepsy, exhibiting severe episodic memory complaints despite normal performance at standardized memory assessment. In a first experiment, the magnitude of autobiographical memory loss was evaluated using retrograde personal memory tasks based on verbal and visual cues. In both conditions, results showed an unusual U-shaped pattern of personal memory impairment, encompassing most of the patients' life, sparing however, periods of the childhood, early adulthood and past several weeks. This profile was suggestive of a long-term consolidation impairment of personal episodes, adequately consolidated over 'short-term' delays but gradually forgotten thereafter. Therefore, in a subsequent experiment, patients were submitted to a protocol specifically devised to investigate short and long-term consolidation of contextually-bound experiences (episodic memory) and context-free information (semantic knowledge and single-items). In the short term (1 h), performance at both contextually-free and contextually-bound memory tasks was intact. After a 6-week delay, however, contextually-bound memory performance was impaired while contextually-free memory performance remained preserved. This effect was independent of task difficulty and the modality of retrieval (recall and recognition). Neuroimaging studies revealed the presence of mild metabolic changes within medial temporal lobe structures. Taken together, these results show the existence of different consolidation systems within declarative memory. They suggest that mild medial temporal lobe dysfunction

  5. Long-Term Treatment with Paroxetine Increases Verbal Declarative Memory and Hippocampal Volume in Posttraumatic Stress Disorder

    Science.gov (United States)

    Vermetten, Eric; Vythilingam, Meena; Southwick, Steven M.; Charney, Dennis S.; Bremner, J. Douglas

    2011-01-01

    Background Animal studies have shown that stress is associated with damage to the hippocampus, inhibition of neurogenesis, and deficits in hippocampal-based memory dysfunction. Studies in patients with posttraumatic stress disorder (PTSD) found deficits in hippocampal-based declarative verbal memory and smaller hippocampal volume, as measured with magnetic resonance imaging (MRI). Recent preclinical evidence has shown that selective serotonin reuptake inhibitors promote neurogenesis and reverse the effects of stress on hippocampal atrophy. This study assessed the effects of long-term treatment with paroxetine on hippocampal volume and declarative memory performance in PTSD. Methods Declarative memory was assessed with the Wechsler Memory Scale–Revised and Selective Reminding Test before and after 9–12 months of treatment with paroxetine in PTSD. Hippocampal volume was measured with MRI. Of the 28 patients who started the protocol, 23 completed the full course of treatment and neuropsychological testing. Twenty patients were able to complete MRI imaging. Results Patients with PTSD showed a significant improvement in PTSD symptoms with treatment. Treatment resulted in significant improvements in verbal declarative memory and a 4.6% increase in mean hippocampal volume. Conclusions These findings suggest that long-term treatment with paroxetine is associated with improvement of verbal declarative memory deficits and an increase in hippocampal volume in PTSD. PMID:14512209

  6. Retrieval under stress decreases the long-term expression of a human declarative memory via reconsolidation.

    Science.gov (United States)

    Larrosa, Pablo Nicolás Fernández; Ojea, Alejandro; Ojea, Ignacio; Molina, Victor Alejandro; Zorrilla-Zubilete, María Aurelia; Delorenzi, Alejandro

    2017-07-01

    Acute stress impairs memory retrieval of several types of memories. An increase in glucocorticoids, several minutes after stressful events, is described as essential to the impairing retrieval-effects of stressors. Moreover, memory retrieval under stress can have long-term consequences. Through what process does the reactivated memory under stress, despite the disrupting retrieval effects, modify long-term memories? The reconsolidation hypothesis proposes that a previously consolidated memory reactivated by a reminder enters a vulnerability phase (labilization) during which it is transiently sensitive to modulation, followed by a re-stabilization phase. However, previous studies show that the expression of memories during reminder sessions is not a condition to trigger the reconsolidation process since unexpressed memories can be reactivated and labilized. Here we evaluate whether it is possible to reactivate-labilize a memory under the impairing-effects of a mild stressor. We used a paradigm of human declarative memory whose reminder structure allows us to differentiate between a reactivated-labile memory state and a reactivated but non-labile state. Subjects memorized a list of five cue-syllables associated with their respective response-syllables. Seventy-two hours later, results showed that the retrieval of the paired-associate memory was impaired when tested 20min after a mild stressor (cold pressor stress (CPS)) administration, coincident with cortisol levels increase. Then, we investigated the long-term effects of CPS administration prior to the reminder session. Under conditions where the reminder initiates the reconsolidation process, CPS impaired the long-term memory expression tested 24h later. In contrast, CPS did not show effects when administered before a reminder session that does not trigger reconsolidation. Results showed that memory reactivation-labilization occurs even when retrieval was impaired. Memory reactivation under stress could hinder

  7. Declarative Networking

    CERN Document Server

    Loo, Boon Thau

    2012-01-01

    Declarative Networking is a programming methodology that enables developers to concisely specify network protocols and services, which are directly compiled to a dataflow framework that executes the specifications. Declarative networking proposes the use of a declarative query language for specifying and implementing network protocols, and employs a dataflow framework at runtime for communication and maintenance of network state. The primary goal of declarative networking is to greatly simplify the process of specifying, implementing, deploying and evolving a network design. In addition, decla

  8. Revising psychoanalytic interpretations of the past. An examination of declarative and non-declarative memory processes.

    Science.gov (United States)

    Davis, J T

    2001-06-01

    The author reviews a contemporary cognitive psychology perspective on memory that views memory as being composed of multiple separate systems. Most researchers draw a fundamental distinction between declarative/explicit and non-declarative/implicit forms of memory. Declarative memory is responsible for the conscious recollection of facts and events--what is typically meant by the everyday and the common psychoanalytic use of the word 'memory'. Non-declarative forms of memory, in contrast, are specialised processes that influence experience and behaviour without representing the past in terms of any consciously accessible content. They operate outside of an individual's awareness, but are not repressed or otherwise dynamically unconscious. Using this theoretical framework, the question of how childhood relationship experiences are carried forward from the past to influence the present is examined. It is argued that incorporating a conceptualisation of non-declarative memory processing into psychoanalytic theory is essential. Non-declarative memory processes are capable of forming complex and sophisticated representations of the interpersonal world. These non-declarative memory processes exert a major impact on interpersonal experience and behaviour that needs to be analysed on its own terms and not mistakenly viewed as a form of resistance.

  9. Long-Term Memory: A Review and Meta-Analysis of Studies of Declarative and Procedural Memory in Specific Language Impairment

    Science.gov (United States)

    Lum, Jarrad A. G.; Conti-Ramsden, Gina

    2013-01-01

    This review examined the status of long-term memory systems in specific language impairment (SLI)--declarative memory and aspects of procedural memory in particular. Studies included in the review were identified following a systematic search of the literature and findings combined using meta-analysis. This review showed that individuals with SLI…

  10. Declarative memory.

    Science.gov (United States)

    Riedel, Wim J; Blokland, Arjan

    2015-01-01

    Declarative Memory consists of memory for events (episodic memory) and facts (semantic memory). Methods to test declarative memory are key in investigating effects of potential cognition-enhancing substances--medicinal drugs or nutrients. A number of cognitive performance tests assessing declarative episodic memory tapping verbal learning, logical memory, pattern recognition memory, and paired associates learning are described. These tests have been used as outcome variables in 34 studies in humans that have been described in the literature in the past 10 years. Also, the use of episodic tests in animal research is discussed also in relation to the drug effects in these tasks. The results show that nutritional supplementation of polyunsaturated fatty acids has been investigated most abundantly and, in a number of cases, but not all, show indications of positive effects on declarative memory, more so in elderly than in young subjects. Studies investigating effects of registered anti-Alzheimer drugs, cholinesterase inhibitors in mild cognitive impairment, show positive and negative effects on declarative memory. Studies mainly carried out in healthy volunteers investigating the effects of acute dopamine stimulation indicate enhanced memory consolidation as manifested specifically by better delayed recall, especially at time points long after learning and more so when drug is administered after learning and if word lists are longer. The animal studies reveal a different picture with respect to the effects of different drugs on memory performance. This suggests that at least for episodic memory tasks, the translational value is rather poor. For the human studies, detailed parameters of the compositions of word lists for declarative memory tests are discussed and it is concluded that tailored adaptations of tests to fit the hypothesis under study, rather than "off-the-shelf" use of existing tests, are recommended.

  11. FEMA Disaster Declarations Summary

    Data.gov (United States)

    Department of Homeland Security — The FEMA Disaster Declarations Summary is a summarized dataset describing all federally declared disasters, starting with the first disaster declaration in 1953,...

  12. Declarative long-term memory and the mesial temporal lobe: Insights from a 5-year postsurgery follow-up study on refractory temporal lobe epilepsy.

    Science.gov (United States)

    Salvato, Gerardo; Scarpa, Pina; Francione, Stefano; Mai, Roberto; Tassi, Laura; Scarano, Elisa; Lo Russo, Giorgio; Bottini, Gabriella

    2016-11-01

    It is largely recognized that the mesial temporal lobe and its substructure support declarative long-term memory (LTM). So far, different theories have been suggested, and the organization of declarative verbal LTM in the brain is still a matter of debate. In the current study, we retrospectively selected 151 right-handed patients with temporal lobe epilepsy with and without hippocampal sclerosis, with a homogeneous (seizure-free) clinical outcome. We analyzed verbal memory performance within a normalized scores context, by means of prose recall and word paired-associate learning tasks. Patients were tested at presurgical baseline, 6months, 2 and 5years after anteromesial temporal lobe surgery, using parallel versions of the neuropsychological tests. Our main finding revealed a key involvement of the left temporal lobe and, in particular, of the left hippocampus in prose recall rather than word paired-associate task. We also confirmed that shorter duration of epilepsy, younger age, and withdrawal of antiepileptic drugs would predict a better memory outcome. When individual memory performance was taken into account, data showed that females affected by left temporal lobe epilepsy for longer duration were more at risk of presenting a clinically pathologic LTM at 5years after surgery. Taken together, these findings shed new light on verbal declarative memory in the mesial temporal lobe and on the behavioral signature of the functional reorganization after the surgical treatment of temporal lobe epilepsy. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Product declaration for cars

    International Nuclear Information System (INIS)

    Gruetter, J.M.

    2000-01-01

    This reports for the Swiss Federal Office of Energy (SFOE) presents the results of a study made on the possible ways of declaring product information on cars. The basic elements of such a declaration are discussed and a recommendation for an energy label for cars is presented. The report discusses the fundamental questions posed such as how long a label should be valid, if comparisons should be made and if it is to be based on CO 2 -emissions or on fuel consumption. Also, the criteria to be used for comparisons - such as vehicle weight, size or power - are looked at and methods of classification are examined along with data fundamentals. Further, the expectations placed on the product declarations with respect to their energetic and economic impact are discussed. The design of the label and the legislature on which it is based are discussed and initial reactions of the automobile industry are noted. The report is rounded off by a discussion of the effects of the declaration in relation to other instruments that have been proposed

  14. Apolipoprotein ɛ4 breaks the association between declarative long-term memory and memory-based orienting of spatial attention in middle-aged individuals.

    Science.gov (United States)

    Salvato, Gerardo; Patai, Eva Z; McCloud, Tayla; Nobre, Anna C

    2016-09-01

    Apolipoprotein (APOE) ɛ4 genotype has been identified as a risk factor for late-onset Alzheimer disease (AD). The memory system is mostly involved in AD, and memory deficits represent its key feature. A growing body of studies has focused on the earlier identification of cognitive dysfunctions in younger and older APOE ɛ4 carriers, but investigation on middle-aged individuals remains rare. Here we sought to investigate if the APOE ɛ4 genotype modulates declarative memory and its influences on perception in the middle of the life span. We tested 60 middle-aged individuals recruited according to their APOE allele variants (ɛ3/ɛ3, ɛ3/ɛ4, ɛ4/ɛ4) on a long-term memory-based orienting of attention task. Results showed that the APOE ɛ4 genotype impaired neither explicit memory nor memory-based orienting of spatial attention. Interestingly, however, we found that the possession of the ɛ4 allele broke the relationship between declarative long-term memory and memory-guided orienting of visuo-spatial attention, suggesting an earlier modulation exerted by pure genetic characteristics on cognition. These findings are discussed in light of possible accelerated brain ageing in middle-aged ɛ4-carriers, and earlier structural changes in the brain occurring at this stage of the lifespan. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. Declarative programming in PROLOG

    Directory of Open Access Journals (Sweden)

    Felician ALECU

    2014-03-01

    Full Text Available The declarative programming by declarative languages is clearly the best option a programmer can have for a completely readable, flexible and extensible code. Today, the economics of programming is clearly focused on the declarative paradigm while most imperative languages are trying to become cost effective by using new added declarative features for productivity and ease of use, like the Java 8. This paper tries to demonstrate a declarative language like PROLOG is perfectly suitable to be used to solve even common programming issue, like deciding an element is part of an array or not.

  16. Schizophrenia patients demonstrate a dissociation on declarative and non-declarative memory tests.

    Science.gov (United States)

    Perry, W; Light, G A; Davis, H; Braff, D L

    2000-12-15

    Declarative memory refers to the recall and recognition of factual information. In contrast, non-declarative memory entails a facilitation of memory based on prior exposure and is typically assessed with priming and perceptual-motor sequencing tasks. In this study, schizophrenia patients were compared to normal comparison subjects on two computerized memory tasks: the Word-stem Priming Test (n=30) and the Pattern Sequence Learning Test (n=20). Word-stem Priming includes recall, recognition (declarative) and priming (non-declarative) components of memory. The schizophrenia patients demonstrated an impaired performance on recall of words with relative improvement during the recognition portion of the test. Furthermore, they performed normally on the priming portion of the test. Thus, on tests of declarative memory, the patients had retrieval deficits with intact performance on the non-declarative memory component. The Pattern Sequence Learning Test utilizes a serial reaction time paradigm to assess non-declarative memory. The schizophrenia patients' serial reaction time was significantly slower than that of comparison subjects. However, the patients' rate of acquisition was not different from the normal comparison group. The data suggest that patients with schizophrenia process more slowly than normal, but have an intact non-declarative memory. The schizophrenia patients' dissociation on declarative vs. non-declarative memory tests is discussed in terms of possible underlying structural impairment.

  17. Long term radiological impact of thorium extraction

    International Nuclear Information System (INIS)

    Menard, S.; Schapira, J.P.

    1995-01-01

    Thorium extraction produces a certain amount of radioactive wastes. Potential long term radiological impact of these residues has been calculated using the recent ICRP-68 ingestion dose factors in connection with the computing code DECAY, developed at Orsay and described in this work. This code solves the well known Bateman's equations which govern the time dependence of a set of coupled radioactive nuclei. Monazites will be very likely the minerals to be exploited first, in case of an extensive use of thorium as nuclear fuel. Because monazites contain uranium as well, mining residues will contain not only the descendants of 232 Th and a certain proportion of non-extracted thorium (taken here to be 5%), but also this uranium, if left in the wastes for economical reasons. If no uranium would be present at all in the mineral, the potential radiotoxicity would strongly decrease in approximately 60 years, at the pace of the 5.8 years period of 228 Ra, which becomes the longest-lived radionuclide of the 4n radioactive family in the residues. Moreover, there is no risk due to radon exhalation, because of the very short period of 220 Rn. These significant differences between uranium and thorium mining have to be considered in view of some estimated long term real radiological impacts due to uranium residues, which could reach a value of the order of 1 mSv/year, the dose limit recommended for the public by the recent ICRP-60. (authors). 15 refs., 4 figs., 3 tabs., 43 appendices

  18. Relationship between cortisol reactivity to psychosocial stress and declarative memory decline during aging: Impact of age and sex.

    Science.gov (United States)

    Dos Santos, Aline Talita; Leyendecker, Dayse Maria D; Costa, Ana Lucia Siqueira; de Souza-Talarico, Juliana Nery

    2018-01-01

    To analyze the relationship between memory performance and the neuroendocrine and cardiovascular response to acute psychosocial stress in healthy older people, and the sex and age impact in this relationship. We randomly selected 100 literate older adults, without cognitive or functional impairment. The neuroendocrine stress response was evaluated by measuring the concentration of salivary cortisol, whereas cardiovascular reactions were determined based on blood pressure and heart rate measures taken before, during and after participant exposure to an acute psychosocial stressor (the Trier social stress test [TSST]). Memory performance was evaluated by applying the word pairs test before and after the TSST. A significant reduction in the word pair test scores was observed after the TSST, and a negative correlation between cortisol concentration and immediate and delayed recall of the word pair. Cortisol concentration associated with age, sex and education explained memory performance variability before and after the TSST. The results showed that the influence of acute stress on memory performance during aging might vary according to age and sex, highlighting potential differences in the vulnerability of older individuals to the neurotoxic effects of stress exposure on memory and consequently on the development of cognitive disorders. Geriatr Gerontol Int 2018; 18: 169-176. © 2017 Japan Geriatrics Society.

  19. 21st Century Declarations

    International Nuclear Information System (INIS)

    Queirolo, F.; Mandl, W.; Ng, J.; Rialhe, A.

    2015-01-01

    The IAEA receives and manages information declared by States, as prescribed by the relevant safeguards agreements, and, together with all other safeguards-relevant information, evaluates it as part of the process supporting safeguards implementation. Within the Division of Information Management (SGIM), the Section for State Declared Information Analysis (ISD) plays a key role in the processing of State declared information - from the transmission of information to the Agency to its ultimate use in the context of the State evaluation process and the drawing of safeguards conclusions. SGIM-ISD handles an increasing variety and volume of these Member State declarations. While the volume of submissions has grown, the submission methods have not kept pace with either the number or the available technology. The paper and supporting presentation will provide an overview of the variety of declarations and transmission methods. The current paradigm and transmission paths between the State authorities and Agency will be evaluated. It will also lay out a future paradigm and desired features of a next generation system. As the Department of Safeguards is currently re-engineering its information technology infrastructure, the future paradigm will be placed within the context of these changes. (author)

  20. The Stockholm declaration

    International Nuclear Information System (INIS)

    1988-03-01

    The Stockholm Declaration was adopted on 21 January 1988 in Stockholm by the President of Argentina, the Prime Minister of Greece, the Prime Minister of India, the President of Mexico, the Prime Minister of Sweden and the President of the United Republic of Tanzania and it expresses the position of these states concerning nuclear disarmament

  1. The Brussels Declaration

    DEFF Research Database (Denmark)

    Holgate, S; Bisgaard, H; Bjermer, L

    2008-01-01

    on Asthma, sponsored by The Asthma, Allergy and Inflammation Research Charity, was developed to call attention to the shortfalls in asthma management and to urge European policy makers to recognise that asthma is a public health problem that should be a political priority. The Declaration urges recognition...

  2. Declarative vs. Procedural Memory: Roles in Second Language Acquisition

    Directory of Open Access Journals (Sweden)

    Laleh Fakhraee Faruji

    2012-04-01

    Full Text Available Memory is not a single faculty but is a combination of multiple distinct abilities (Schacter, 1987. The declarative-procedural distinction is used both with regard to knowledge and memory that stores this knowledge. Ellis (2008 used the terms explicit/implicit, and declarative/procedural interchangeably. In this article the researcher aims at identifying the different aspects of declarative/procedural memory, interaction between these two types of memory, and the role they may play in second language acquisition.

  3. Oscillatory Reinstatement Enhances Declarative Memory.

    Science.gov (United States)

    Javadi, Amir-Homayoun; Glen, James C; Halkiopoulos, Sara; Schulz, Mei; Spiers, Hugo J

    2017-10-11

    Declarative memory recall is thought to involve the reinstatement of neural activity patterns that occurred previously during encoding. Consistent with this view, greater similarity between patterns of activity recorded during encoding and retrieval has been found to predict better memory performance in a number of studies. Recent models have argued that neural oscillations may be crucial to reinstatement for successful memory retrieval. However, to date, no causal evidence has been provided to support this theory, nor has the impact of oscillatory electrical brain stimulation during encoding and retrieval been assessed. To explore this we used transcranial alternating current stimulation over the left dorsolateral prefrontal cortex of human participants [ n = 70, 45 females; age mean (SD) = 22.12 (2.16)] during a declarative memory task. Participants received either the same frequency during encoding and retrieval (60-60 or 90-90 Hz) or different frequencies (60-90 or 90-60 Hz). When frequencies matched there was a significant memory improvement (at both 60 and 90 Hz) relative to sham stimulation. No improvement occurred when frequencies mismatched. Our results provide support for the role of oscillatory reinstatement in memory retrieval. SIGNIFICANCE STATEMENT Recent neurobiological models of memory have argued that large-scale neural oscillations are reinstated to support successful memory retrieval. Here we used transcranial alternating current stimulation (tACS) to test these models. tACS has recently been shown to induce neural oscillations at the frequency stimulated. We stimulated over the left dorsolateral prefrontal cortex during a declarative memory task involving learning a set of words. We found that tACS applied at the same frequency during encoding and retrieval enhances memory. We also find no difference between the two applied frequencies. Thus our results are consistent with the proposal that reinstatement of neural oscillations during retrieval

  4. Declarative Programming in Java

    Directory of Open Access Journals (Sweden)

    Razvan DINA

    2014-03-01

    Full Text Available Despite the code is rarely self-explanatory, the imperative programming languages are the most commonly used in our days by the programmers all over the world and Java is definitely the lead language in popularity. This paper tries to conclude if there are any chances to use the most popular programming language of the moment in a declarative manner, even if Java itself is an intrinsic imperative language.

  5. Twitter weather warnings: Communicating risk in 140 characters-the impact of imperative and declarative message style on weather risk perception and behavioral intentions.

    Science.gov (United States)

    Rainear, Adam M; Lachlan, Kenneth A; Spence, Patric R

    Understanding how individuals utilize risk messages is important for protecting lives and gaining compliance toward safe behaviors. Recent advances in technology afford users with timeliness when needing to acquire information, and research investigating imperative and declarative message styles suggests utilizing both strategies is most effective. Similarly, the element of time can play a role when an individual engages in certain behaviors. This study employed an experimental design to better understand how imperative and declarative tweets, and time can contribute to risk perceptions and behavioral intentions. Results indicate the most negative affect is experienced after receiving an imperative-only tweet in a short-lead time condition, whereas a tweet utilizing both message styles in a long-lead time condition induces the most fear. Future research should investigate stylistic message elements on new media platforms to better understand how messages can be effectively sent and received by the intended audience within character-limited platforms.

  6. Environmental Labels and Declarations

    DEFF Research Database (Denmark)

    Frydendal, Jeppe; Hansen, Lisbeth; Bonou, Alexandra

    2018-01-01

    Based on the terminology and structure developed by the International Organization for Standardization, a description is given on the types of ecolabels that build on life cycle assessments. Focus is on type I labels that point out products and services with an overall environmental preferability...... of labelling, the use of ecolabels in marketing, and the way ecolabels help build a market for “greener products”. Type III labels—or Environmental Product Declarations—are also briefly described with indicative examples from the building sector, a declaration for office furniture, and an introduction is given...... to the European Commission’s programme for product—and organisational environmental footprints ....

  7. FEMA Disaster Declaration Summary -shp

    Data.gov (United States)

    Department of Homeland Security — This dataset lists all official FEMA Disaster Declarations. This is raw, unedited data from FEMA's National Emergency Management Information System (NEMIS) and as...

  8. FEMA Disaster Declaration Summary - API

    Data.gov (United States)

    Department of Homeland Security — This dataset lists all official FEMA Disaster Declarations. This is raw, unedited data from FEMA's National Emergency Management Information System (NEMIS) and as...

  9. WTO ministerial conference adopts declaration on TRIPS and public health.

    Science.gov (United States)

    Elliott, Richard

    2002-03-01

    In November 2001, the 4th Ministerial Conference of the World Trade Organization adopted a Ministerial Declaration on public health and the WTO's Agreement on Trade-Related Aspects of Intellectual Property Rights (the "TRIPS Agreement"). The declaration represents a modest advance in addressing concerns that strict patent laws, and threats of trade sanctions, will be a barrier to most of the world's people with HIV/AIDS accessing affordable medicines. The full significance of the declaration remains to be seen, as it depends on what political impact it has at the WTO and on its member countries, and what legal impact it will have in the interpretation of the TRIPS Agreement.

  10. Cairo youth declaration.

    Science.gov (United States)

    Ladjali, M

    1995-01-01

    More than 100 young people from 56 countries voiced their needs and concerns in a Youth Consultation held just before the International Conference on Population and Development (ICPD), August 31 to September 4, 1994. Many journalists from the international press followed the consultation and interviewed the youths, with a short film even produced on the proceedings. After discussing the main topics of the ICPD, participants produced a Youth Declaration with recommendations for action and conclusions for partnership. More than 20 participants remained in Cairo to present consultation conclusions in well-attended workshops and role play at the ICPD NGO Forum. One representative presented the Youth Declaration in ICPD plenary session. These young men and women from all regions of the world, from a diversity of cultural, religious, and political backgrounds found common ground on the need for population concerns to be explicitly and consistently integrated with development in the context of a just and equitable international economic system; a strong focus upon youth education and mobilization in the areas of adolescent health, sexual and reproductive health, the environment, human rights, and political and economic systems; and the sense that now is the time to act at the individual, organizational, national, and national levels. Education and safe sexual behavior do not encourage promiscuity. On the contrary, they promote and enhance healthy, responsible relationships, minimizing the incidence of unplanned pregnancies and sexually transmitted infections when sex does take place. Participants recommend promoting peer education; involving and educating peers through artistic activities such as music and drama; implementing peer counseling and raising awareness through one-on-one interaction, group discussions, printed media, and radio programs; organizing services for youths in a variety of settings; creating jobs for youths in cooperatives and businesses; educating

  11. Long-term impact of zinc supplementation in sows

    NARCIS (Netherlands)

    Riet, Van Miriam M.J.; Bos, Emilie Julie; Ampe, Bart; Bikker, Paul; Vanhauteghem, Donna; Bockstaele, Van Filip; Cornillie, Pieter; Broeck, Van Den Wim; Laing, Du Gijs; Maes, Dominiek; Tuyttens, Frank A.M.; Janssens, Geert P.J.; Millet, Sam

    2018-01-01

    Objectives: To evaluate the long-term impact of zinc (Zn) supplementation on performance and Zn status biomarkers in sows and on whether this possible impact depends on housing conditions. Materials and methods: Six groups of sows were allotted to group housing on two different floor types during

  12. Predicting the long-term citation impact of recent publications

    NARCIS (Netherlands)

    Stegehuis, Clara; Litvak, Nelli; Waltman, Ludo

    2015-01-01

    A fundamental problem in citation analysis is the prediction of the long-term citation impact of recent publications. We propose a model to predict a probability distribution for the future number of citations of a publication. Two predictors are used: The impact factor of the journal in which a

  13. Predicting the long-term citation impact of recent publications

    NARCIS (Netherlands)

    Stegehuis, Clara; Litvak, Nelli; Waltman, Ludo

    A fundamental problem in citation analysis is the prediction of the long-term citation impact of recent publications. We propose a model to predict a probability distribution for the future number of citations of a publication. Two predictors are used: the impact factor of the journal in which a

  14. Product declaration for cars; Warendeklaration fuer Personenwagen

    Energy Technology Data Exchange (ETDEWEB)

    Gruetter, J.M.

    2000-07-01

    This reports for the Swiss Federal Office of Energy (SFOE) presents the results of a study made on the possible ways of declaring product information on cars. The basic elements of such a declaration are discussed and a recommendation for an energy label for cars is presented. The report discusses the fundamental questions posed such as how long a label should be valid, if comparisons should be made and if it is to be based on CO{sub 2}-emissions or on fuel consumption. Also, the criteria to be used for comparisons - such as vehicle weight, size or power - are looked at and methods of classification are examined along with data fundamentals. Further, the expectations placed on the product declarations with respect to their energetic and economic impact are discussed. The design of the label and the legislature on which it is based are discussed and initial reactions of the automobile industry are noted. The report is rounded off by a discussion of the effects of the declaration in relation to other instruments that have been proposed.

  15. Long-term impact of sales promotion on brand image

    Directory of Open Access Journals (Sweden)

    Danijela Mandić

    2009-12-01

    Full Text Available Sales promotion (SP is an inevitable tool in the marketing communications mix, especially in the FMCG markets, due to pressures such as retailers’ growing demands and increasing competition. This has proven to be an issue for many companies, especially those with a premium brand positioning and those concerned about the impact that SP might have on the long-term image of the company. Despite the fact that literature is replete with research on SP, it seems to be vastly generalized and mostly focused on price reductions. Thus, this paper aims to analyze and discuss the issue of the long-term impact that SP has on companies, especially on premium brands in the FMCG markets. It concludes that, when used properly and strategically, SP may have a positive long-term impact on brands.

  16. Concurrency & Asynchrony in Declarative Workflows

    DEFF Research Database (Denmark)

    Debois, Søren; Hildebrandt, Thomas; Slaats, Tijs

    2015-01-01

    of concurrency in DCR Graphs admits asynchronous execution of declarative workflows both conceptually and by reporting on a prototype implementation of a distributed declarative workflow engine. Both the theoretical development and the implementation is supported by an extended example; moreover, the theoretical....... In this paper, we pro- pose a notion of concurrency for declarative process models, formulated in the context of Dynamic Condition Response (DCR) graphs, and exploiting the so-called “true concurrency” semantics of Labelled Asynchronous Transition Systems. We demonstrate how this semantic underpinning...

  17. Impact of Patients' Communication with the Medical Practitioners, on Their Adherence Declared to Preventive Behaviours, Five Years after a Coronary Angiography, in Luxembourg.

    Directory of Open Access Journals (Sweden)

    Michèle Baumann

    Full Text Available Patients of the National Institute of Cardiac Surgery and Interventional Cardiology in Luxembourg who underwent coronary angiography were surveyed for hypertension, hypercholesterolemia, diabetes and overweight/obesity between 2008/9 and 2013/4. For each cardiovascular risk factor (CVRFs, we analysed the associations between the quality of the patients' communication with the medical practitioner and their adherence declared to preventive behaviours.1,289 completed a self-administered questionnaire on communication with the medical practitioner (P'Com-5 items scale; Cronbach 0.87. 61.8% stopped smoking, 57.9% reduced or stopped their consumption of salt, 71.9% of fat, and 62.8% of sugar, and whereas 65% increased their consumption of fruit and vegetables and 19.8% increased their physical activity. Around 37% reported having made changes following their doctor's advice. 90% were followed by a cardiologist and 95.9% by an attending physician.No link was observed between declaration of physical activity, smoking, fats, and quality of communication. Significant associations: for increased consumption of fruit and vegetables was linked with the quality of doctor-patient communication when patients were overweight (OR = 1.081, obese (OR = 1.130, hypercholesterolemic (OR = 1.102, hypertensive (OR = 1.084 or diabetic (OR = 1.103. Reduction in salt intake was linked only to patients with hypertension (OR = 1.102, whereas reduction or cessation of sugar consumption was linked to overweight (OR = 1.093, and more so obese, (OR = 1.106, hypercholesterolemics (OR = 1.103 and diabetics (OR = 1.173.Good doctor-patient communication was related to nutrition, particularly increased consumption of fresh fruits and vegetables. Accurate perception of CVRFs by both patients and medical practitioners is essential for CV protection. The aim of instructing patients is to encourage them to make informed decisions about how to change their lifestyle. In routinely, P

  18. FEMA Current Disaster Declarations -shp

    Data.gov (United States)

    Department of Homeland Security — This dataset lists the current Disaster Declarations in Shapefile. This data was compiled and distributed by FEMA Mapping and Analysis Center (MAC). Metadata file...

  19. FEMA Historical Disaster Declarations - shp

    Data.gov (United States)

    Department of Homeland Security — The Historical Disaster Declarations provides geospatial view to the Robert T. Stafford Disaster Relief and Emergency Assistance Act (referred to as the Stafford Act...

  20. 21 CFR 701.13 - Declaration of net quantity of contents.

    Science.gov (United States)

    2010-04-01

    ... shall be expressed in terms of weight, measure, numerical count, or a combination of numerical count and... gallon and labeled in terms of weight or fluid measure: (1) The declaration shall be expressed both in... and labeled in terms of weight or fluid measure, the declaration shall be expressed in pounds for...

  1. The Historical Significance of the Universal Declaration.

    Science.gov (United States)

    Eide, Asbjorn

    1998-01-01

    Explains the historical significance of the Universal Declaration of Human Rights. Focuses on the initiative for the Declaration and its elaboration, the precursors to modern human rights, the foundation of the Declaration, the rights contained in the Universal Declaration, three modes of human rights analysis, and global governance and human…

  2. Long-term socioeconomic impacts of flooding in Bangladesh

    Science.gov (United States)

    Jina, A.

    2013-05-01

    Natural disasters lead to myriad negative impacts upon society, causing loss of life, property, and income. Among disasters, floods annually affect the most people, and lead to widespread negative outcomes, particularly in developing countries. While immediate effects of disasters are readily observed, long-term socioeconomic effects have received little attention. Recent work in development economics finds that environmental exposure in early life can have negative impacts upon later outcomes in health, education, and labor markets. Such research is problematic for disasters, however, as objective measurements of hazard exposure are difficult to obtain. This study develops a remote sensing method to detect flooding in Bangladesh, one of the most flood-prone countries, using MODIS 8-day composite data. This approach addresses one of the main problems in the literature on the social impacts of disasters by deriving an objective measure rather than using self-reported damages. Flood data from 2000-2012 is matched to geolocated social surveys conducted by the Bangladesh government to identify impacts of exposure to floods at critical periods of life. While flooding is noted to be a natural and important part of ecosystem functioning in Bangladesh, we aim to understand the impacts of a flood of greater than normal magnitude or abnormal timing to identify the effects on human capital formation. We find that an increase in flooding of one standard deviation (SD) above the mean in the birth month leads to a 3% increase in stunting (2 SD below cohort height). This has implications for physical and cognitive development, shown elsewhere to persist to adulthood. We find that children from households that are exposed to floods while in elementary school are more likely to drop out. Other impacts will be identified in the course of this research. The stated impacts suggest that the long-term health and economic fortunes of the rural poor in Bangladesh are significantly

  3. Long term impacts of international outsourcing of manufacturing on sustainability

    DEFF Research Database (Denmark)

    Moosavirad, Seyed Hamed; Kara, Sami; Hauschild, Michael Zwicky

    2014-01-01

    International outsourcing seems to be a cost efficient way of production. However, there are serious concerns about its long term impacts on the environmental, social and economic sustainability. This paper aims to quantify these impacts by using input output analysis, linear programming and system......% international outsourcing scenario and the baseline scenario due to their differences in production technologies. © 2014 CIRP....... dynamics in a case study including European electrical industry (outsourcer), Chinese electrical industry (outsourcee) and their main suppliers. Results depict the differences related to the total CO2 emissions, the number of employees and the gross value added of these two regions between a 10...

  4. Working, declarative and procedural memory in specific language impairment

    Science.gov (United States)

    Lum, Jarrad A.G.; Conti-Ramsden, Gina; Page, Debra; Ullman, Michael T.

    2012-01-01

    According to the Procedural Deficit Hypothesis (PDH), abnormalities of brain structures underlying procedural memory largely explain the language deficits in children with specific language impairment (SLI). These abnormalities are posited to result in core deficits of procedural memory, which in turn explain the grammar problems in the disorder. The abnormalities are also likely to lead to problems with other, non-procedural functions, such as working memory, that rely at least partly on the affected brain structures. In contrast, declarative memory is expected to remain largely intact, and should play an important compensatory role for grammar. These claims were tested by examining measures of working, declarative and procedural memory in 51 children with SLI and 51 matched typically-developing (TD) children (mean age 10). Working memory was assessed with the Working Memory Test Battery for Children, declarative memory with the Children’s Memory Scale, and procedural memory with a visuo-spatial Serial Reaction Time task. As compared to the TD children, the children with SLI were impaired at procedural memory, even when holding working memory constant. In contrast, they were spared at declarative memory for visual information, and at declarative memory in the verbal domain after controlling for working memory and language. Visuo-spatial short-term memory was intact, whereas verbal working memory was impaired, even when language deficits were held constant. Correlation analyses showed neither visuo-spatial nor verbal working memory was associated with either lexical or grammatical abilities in either the SLI or TD children. Declarative memory correlated with lexical abilities in both groups of children. Finally, grammatical abilities were associated with procedural memory in the TD children, but with declarative memory in the children with SLI. These findings replicate and extend previous studies of working, declarative and procedural memory in SLI. Overall, we

  5. Proposition of declaration tending to create a commission of inquiry relative to the impact in nourishment and on health of foodstuff treated by irradiation

    International Nuclear Information System (INIS)

    2005-01-01

    In application of articles 140 and following of the regulation, is created a commission of inquiry with thirty members relative to the impact in foodstuff and on health of irradiated food. It should examines the respect of the regulation concerning the labelling, the production and imports; it should determine the real place of this food in the French diet and the impact on this diet that could imply an opening of the market to the food imported from third country to european Union; it should evaluate the risk for human and animal health of their consumption. (N.C.)

  6. Impact of long-term and short-term therapies on seminal parameters

    Directory of Open Access Journals (Sweden)

    Jlenia Elia

    2013-04-01

    Full Text Available Aim: The aim of this work was: i to evaluate the prevalence of male partners of subfertile couples being treated with long/short term therapies for non andrological diseases; ii to study their seminal profile for the possible effects of their treatments on spermatogenesis and/or epididymal maturation. Methods: The study group was made up of 723 subjects, aged between 25 and 47 years. Semen analysis was performed according to World Health Organization (WHO guidelines (1999. The Superimposed Image Analysis System (SIAS, which is based on the computerized superimposition of spermatozoa images, was used to assess sperm motility parameters. Results: The prevalence of subjects taking pharmacological treatments was 22.7% (164/723. The prevalence was 3.7% (27/723 for the Short-Term Group and 18.9% (137/723 for the Long-Term Group. The subjects of each group were also subdivided into subgroups according to the treatments being received. Regarding the seminal profile, we did not observe a significant difference between the Long-Term, Short-Term or the Control Group. However, regarding the subgroups, we found a significant decrease in sperm number and progressive motility percentage in the subjects receiving treatment with antihypertensive drugs compared with the other subgroups and the Control Group. Conclusions: In the management of infertile couples, the potential negative impact on seminal parameters of any drugs being taken as Long-Term Therapy should be considered. The pathogenic mechanism needs to be clarified.

  7. Impact of Long-Term Care on Retirement Wellness.

    Science.gov (United States)

    Rappaport, Anna M

    2015-01-01

    Retirement wellness is the result of retiring at an appropriate age, saving enough and managing risks appropriately. One of the major risks that often is not addressed effectively is the long-term care (LTC) risk, i.e., the risk of needing help due to physical or cognitive limitations. In 2014, the Society of Actuaries issued a call for papers on the link between LTC and retirement security. This article will discuss the topic of LTC and retirement security broadly, drawing from several of the papers. Some of the topics include the impact of LTC on the individual, family members and caregivers; modeling results showing the impact of LTC on assets needed for a secure retirement; alternative methods of financing LTC; the link between housing decisions and LTC; and some ideas for the future.

  8. Determining long-term regional erosion rates using impact craters

    Science.gov (United States)

    Hergarten, Stefan; Kenkmann, Thomas

    2015-04-01

    More than 300,000 impact craters have been found on Mars, while the surface of Moon's highlands is even saturated with craters. In contrast, only 184 impact craters have been confirmed on Earth so far with only 125 of them exposed at the surface. The spatial distribution of these impact craters is highly inhomogeneous. Beside the large variation in the age of the crust, consumption of craters by erosion and burial by sediments are the main actors being responsible for the quite small and inhomogeneous crater record. In this study we present a novel approach to infer long-term average erosion rates at regional scales from the terrestrial crater inventory. The basic idea behind this approach is a dynamic equilibrium between the production of new craters and their consumption by erosion. It is assumed that each crater remains detectable until the total erosion after the impact exceeds a characteristic depth depending on the crater's diameter. Combining this model with the terrestrial crater production rate, i.e., the number of craters per unit area and time as a function of their diameter, allows for a prediction of the expected number of craters in a given region as a function of the erosion rate. Using the real crater inventory, this relationship can be inverted to determine the regional long-term erosion rate and its statistical uncertainty. A limitation by the finite age of the crust can also be taken into account. Applying the method to the Colorado Plateau and the Deccan Traps, both being regions with a distinct geological history, yields erosion rates in excellent agreement with those obtained by other, more laborious methods. However, these rates are formally exposed to large statistical uncertainties due to the small number of impact craters. As higher crater densities are related to lower erosion rates, smaller statistical errors can be expected when large regions in old parts of the crust are considered. Very low long-term erosion rates of less than 4

  9. Long-term environmental impacts of geologic repositories

    International Nuclear Information System (INIS)

    Pigford, T.H.

    1983-05-01

    This paper summarizes a study of the long-term environmental impacts of geologic repositories for radioactive wastes. Conceptual repositories in basalt, granite, salt, and tuff were considered. Site-specific hydrological and geochemical parameters were used wherever possible, supplemented with generic parameters when necessary. Radiation doses to future maximally exposed individuals who use the contaminated groundwater and surface water were calculated and compared with a performance criterion of 10 -4 Sv/yr for radiation exposures from probable events. The major contributors to geologic isolation are the absence of groundwater if the repository is in natural salt, the slow dissolution of key radioelements as limited by solubility and by diffusion and convection in groundwater, long water travel times from the waste to the environment, and sorption retardation in the media surrounding the repository. In addition, dilution by surface water can considerably reduce the radiation exposures that result from the small fraction of the waste radioactivity that may ultimately reach the environment. Estimates of environmental impacts are made both for unreprocessed spent fuel and for reprocessing wastes. Accelerated dissolution of waste exposed to groundwater during the period of repository heating is also considered. This study of environmental impacts is a portion of a more comprehensive study of geologic waste disposal carried out by the Waste Isolation System Panel of the US National Research Council

  10. Declaration of income for 2005

    CERN Multimedia

    HR Department

    2006-01-01

    Information from the Legal Service and the HR Department Information for members of the personnel residing in France Following the introduction of the internal taxation of salaries and emoluments of members of the CERN personnel on 1st January 2005 (cf. Bulletin No. 48-49/2005), the French Finance Ministry has communicated the following information on the procedure for completing the 2005 declaration of income form, which must be returned by 31 May 2006 at the latest. All members of the personnel*) residing in France, whether or not they are of French nationality, are required to complete a declaration of income for 2005 according to the following instructions and to return a signed copy to their local tax office by 31 May 2006 at the latest. Members of the personnel should receive an income declaration form for 2005 at the beginning of May. Those who do not receive a form directly should obtain one from their local 'Centre des Impôts', Trésorerie' or 'Mairie', or download one from the Finance Ministry...

  11. The Birth of the Universal Declaration of Human Rights.

    Science.gov (United States)

    Cooper, Michael

    1998-01-01

    Outlines the history of the ideals and enactment of the United Nations' Universal Declaration of Human Rights (UDHR). Includes a discussion of the origins of the concept of human rights, the impact of World War II, the role of nongovernmental organizations, and the process of drafting and adopting the UDHR. (DSK)

  12. How Effective Is Example Generation for Learning Declarative Concepts?

    Science.gov (United States)

    Rawson, Katherine A.; Dunlosky, John

    2016-01-01

    Declarative concepts (i.e., key terms and corresponding definitions for abstract concepts) represent foundational knowledge that students learn in many content domains. Thus, investigating techniques to enhance concept learning is of critical importance. Various theoretical accounts support the expectation that example generation will serve this…

  13. Which Technique Is Most Effective for Learning Declarative Concepts--Provided Examples, Generated Examples, or Both?

    Science.gov (United States)

    Zamary, Amanda; Rawson, Katherine A.

    2018-01-01

    Students in many courses are commonly expected to learn declarative concepts, which are abstract concepts denoted by key terms with short definitions that can be applied to a variety of scenarios as reported by Rawson et al. ("Educational Psychology Review" 27:483-504, 2015). Given that declarative concepts are common and foundational in…

  14. Working, declarative and procedural memory in specific language impairment

    DEFF Research Database (Denmark)

    Lum, J. A. G.; Conti-Ramsden, G.; Page, D.

    2012-01-01

    at declarative memory for visual information, and at declarative memory in the verbal domain after controlling for working memory and language. Visuo-spatial short-term memory was intact, whereas verbal working memory was impaired, even when language deficits were held constant. Correlation analyses showed......According to the Procedural Deficit Hypothesis (PDH), abnormalities of brain structures underlying procedural memory largely explain the language deficits in children with specific language impairment (SLI). These abnormalities are posited to result in core deficits of procedural memory, which...... in turn explain the grammar problems in the disorder. The abnormalities are also likely to lead to problems with other, non-procedural functions, such as working memory, that rely at least partly on the affected brain structures. In contrast, declarative memory is expected to remain largely intact...

  15. To prevent the diversion of chemical products or installations. CWC - An international regulation on chemical products. Handbook of PCOD declaration. Handbook for Table 1 declaration. Handbook for Table 2 declaration. Handbook for Table 3 declaration

    International Nuclear Information System (INIS)

    2006-01-01

    The Chemical Weapons Convention (CWC) aims at preventing risks of diversion of chemical products and installations, and therefore may concern various types of companies. A first document, illustrated by graphs, figures and tables proposes an overview of concerned actors, sectors, products and usages, of involved chemical reactions and associated production thresholds, and of levels of concerned international trade for a country. It mentions obligations and indicates some of the concerned products which are classified in four categories: Discrete Organic Chemicals, Table 1, Table 2, and Table 3. The four other documents are handbooks aimed at defining and describing whether and how to make associated declarations about these four categories. They recall the definition of the concerned products, indicate the concerned establishments, describe how to assess whether a declaration must be made, present the associated declarations and describe how to complete them in terms of method (paper form or through the internet) and of content

  16. Long term radiological impact of a uranium mine restoration

    International Nuclear Information System (INIS)

    Mora, Veronica; Bordonaba Marisa; Sanchez Guillermo

    2008-01-01

    During the 1990s, many uranium mines were closed as consequence of low prices of this mineral. It was due to a decrease in the demand for uranium and an increase in the overall supply. The resulting was a further complicated implementation of sites restorations. This report deals with one of the relevant aspects of the radiological protection scope: 'the evaluation of the long term radiological impact in the population due to the uranium mine restoration activities' for the uranium mine sited in Saelices el Chico (Salamanca, Spain). These restoration activities have basically consisted of recovering the original site by filling the old open pits with the material stockpiled in the waste dumps. The main problems associated with this material include radon release and particles emission. The strategy used to solve this problem has been covered these structures with a layer with beds of clay material rock, waste material and a cover tree. The pathways considered for the radiological impact have been: 1) Inhalation; 2) Ingestion of contaminated water, milk, vegetables and meat; 3) External exposure from clouds immersion, grounds concentrations and direct gamma radiation. Three computer codes have been used with the object of evaluating the above-mentioned impact. Two of them are well-known NRC (Nuclear Regulatory Commission) codes: RESRAD 6.30 and MILDOS-AREA. We have also applied DOEFLURA, developed in ENUSA [1, 2, 3]. Four scenarios have been studied: Resident Farmer Scenario, Resident scenario, Livestock pasture scenario and Forest scenario, Estimation of radioactive doses for the member of the public in the different scenarios has been calculated with this programme. A period of 3500 years from now has been studied. (author)

  17. 43 CFR 46.420 - Terms used in an environmental impact statement.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Terms used in an environmental impact... IMPLEMENTATION OF THE NATIONAL ENVIRONMENTAL POLICY ACT OF 1969 Environmental Impact Statements § 46.420 Terms used in an environmental impact statement. The following terms are commonly used to describe concepts...

  18. The International Lunar Decade Declaration

    Science.gov (United States)

    Beldavs, V.; Foing, B.; Bland, D.; Crisafulli, J.

    2015-10-01

    The International Lunar Decade Declaration was discussed at the conference held November 9-13, 2014 in Hawaii "The Next Giant Leap: Leveraging Lunar Assets for Sustainable Pathways to Space" - http://2014giantleap.aerospacehawaii.info/ and accepted by a core group that forms the International Lunar Decade Working Group (ILDWG) that is seeking to make the proposed global event and decade long process a reality. The Declaration will be updated from time to time by members of the ILDWreflecting new knowledge and fresh perspectives that bear on building a global consortium with a mission to progress from lunar exploration to the transformation of the Moon into a wealth gene rating platform for the expansion of humankind into the solar system. When key organizations have endorsed the idea and joined the effort the text of the Declaration will be considered final. An earlier International Lunar Decade proposal was issued at the 8th ICEUM Conference in 2006 in Beijing together with 13 specific initiatives for lunar exploration[1,2,3]. These initiatives have been largely implemented with coordination among the different space agencies involved provided by the International Lunar Exploration Working Group[2,3]. The Second International Lunar Decade from 2015 reflects current trends towards increasing involvement of commercial firms in space, particularly seeking opportunities beyond low Earth orbit. The central vision of the International Lunar Decade is to build the foundations for a sustainable space economy through international collaboration concurrently addressing Lunar exploration and building a shared knowledge base;Policy development that enables collabo rative research and development leading to lunar mining and industrial and commercial development;Infrastructure on the Moon and in cislunar space (communications, transport, energy systems, way-stations, other) that reduces costs, lowers risks and speeds up the time to profitable operations;Enabling technologies

  19. Long-term nutritional impact of sleeve gastrectomy.

    Science.gov (United States)

    Caron, M; Hould, F S; Lescelleur, O; Marceau, S; Lebel, S; Julien, F; Simard, S; Biertho, Laurent

    2017-10-01

    Sleeve gastrectomy (SG) has become a predominant bariatric procedure throughout the world. However, the long-term nutritional impact of this procedure is unknown. To describe the nutritional deficiencies before and after SG and to analyze the influence of baseline weight on nutritional status. University-affiliated tertiary care center. All patients who underwent SG as a standalone procedure between 2008 and 2012 were included in this study. Patients were given multivitamin supplementation. Data were obtained from our prospectively maintained electronic database and are reported as mean ± standard deviation and percentage. Bivariate analyses were conducted to evaluate the influence of selected variables on outcomes. The mean age of the 537 patients was 48.0 ± 11.3 years, with an initial body mass index of 48.1 ± 8.7 kg/m 2 . Excess weight loss and total weight loss were 56.2% and 28.0% at 1 year and 43.0% and 21.1% at 5 years, respectively (Pvitamin B12 in 30.3% and 16.4% (Pvitamin D 63.2% and 24.3% (Pvitamin A insufficiency peaked from 7.9% preoperatively to 28.7% at 3 months (Pvitamin B12 and vitamin D. Nutritional deficiencies are common in patients with morbid obesity before and after surgery. Preoperative supplementation and long-term nutritional follow-up are required to prevent nutritional deficiencies. Copyright © 2017 American Society for Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

  20. Declarations on euthanasia and assisted dying.

    Science.gov (United States)

    Inbadas, Hamilton; Zaman, Shahaduz; Whitelaw, Sandy; Clark, David

    2017-10-01

    Declarations on end-of-life issues are advocacy interventions that seek to influence policy, raise awareness and call others to action. Despite increasing prominence, they have attracted little attention from researchers. This study tracks the emergence, content, and purpose of declarations concerned with assisted dying and euthanasia, in the global context. The authors identified 62 assisted dying/euthanasia declarations covering 1974-2016 and analyzed them for originating organization, geographic scope, format, and stated viewpoint on assisted dying/euthanasia. The declarations emerged from diverse organizational settings and became more frequent over time. Most opposed assisted dying/euthanasia.

  1. Declarations on euthanasia and assisted dying

    Science.gov (United States)

    Inbadas, Hamilton; Zaman, Shahaduz; Whitelaw, Sandy; Clark, David

    2017-01-01

    ABSTRACT Declarations on end-of-life issues are advocacy interventions that seek to influence policy, raise awareness and call others to action. Despite increasing prominence, they have attracted little attention from researchers. This study tracks the emergence, content, and purpose of declarations concerned with assisted dying and euthanasia, in the global context. The authors identified 62 assisted dying/euthanasia declarations covering 1974–2016 and analyzed them for originating organization, geographic scope, format, and stated viewpoint on assisted dying/euthanasia. The declarations emerged from diverse organizational settings and became more frequent over time. Most opposed assisted dying/euthanasia. PMID:28398131

  2. The Dublin Declaration on Maternal Health Care and Anti-Abortion Activism

    Science.gov (United States)

    2017-01-01

    Abstract The Dublin Declaration on Maternal Healthcare—issued by self-declared pro-life activists in Ireland in 2012—states unequivocally that abortion is never medically necessary, even to save the life of a pregnant woman. This article examines the influence of the Dublin Declaration on abortion politics in Latin America, especially El Salvador and Chile, where it has recently been used in pro-life organizing to cast doubt on the notion that legalizing abortion will reduce maternal mortality. Its framers argue that legalizing abortion will not improve maternal mortality rates, but reproductive rights advocates respond that the Dublin Declaration is junk science designed to preserve the world’s most restrictive abortion laws. Analyzing the strategy and impact of the Dublin Declaration brings to light one of the tactics used in anti-abortion organizing. PMID:28630540

  3. Trends in compulsory licensing of pharmaceuticals since the Doha Declaration: a database analysis.

    Science.gov (United States)

    Beall, Reed; Kuhn, Randall

    2012-01-01

    It is now a decade since the World Trade Organization (WTO) adopted the "Declaration on the TRIPS Agreement and Public Health" at its 4th Ministerial Conference in Doha. Many anticipated that these actions would lead nations to claim compulsory licenses (CLs) for pharmaceutical products with greater regularity. A CL is the use of a patented innovation that has been licensed by a state without the permission of the patent title holder. Skeptics doubted that many CLs would occur, given political pressure against CL activity and continued health system weakness in poor countries. The subsequent decade has seen little systematic assessment of the Doha Declaration's impact. We assembled a database of all episodes in which a CL was publically entertained or announced by a WTO member state since 1995. Broad searches of CL activity were conducted using media, academic, and legal databases, yielding 34 potential CL episodes in 26 countries. Country- and product-specific searches were used to verify government participation, resulting in a final database of 24 verified CLs in 17 nations. We coded CL episodes in terms of outcome, national income, and disease group over three distinct periods of CL activity. Most CL episodes occurred between 2003 and 2005, involved drugs for HIV/AIDS, and occurred in upper-middle-income countries (UMICs). Aside from HIV/AIDS, few CL episodes involved communicable disease, and none occurred in least-developed or low-income countries. Given skepticism about the Doha Declaration's likely impact, we note the relatively high occurrence of CLs, yet CL activity has diminished markedly since 2006. While UMICs have high CL activity and strong incentives to use CLs compared to other countries, we note considerable countervailing pressures against CL use even in UMICs. We conclude that there is a low probability of continued CL activity. We highlight the need for further systematic evaluation of global health governance actions. Please see later in the

  4. Trends in compulsory licensing of pharmaceuticals since the Doha Declaration: a database analysis.

    Directory of Open Access Journals (Sweden)

    Reed Beall

    2012-01-01

    Full Text Available BACKGROUND: It is now a decade since the World Trade Organization (WTO adopted the "Declaration on the TRIPS Agreement and Public Health" at its 4th Ministerial Conference in Doha. Many anticipated that these actions would lead nations to claim compulsory licenses (CLs for pharmaceutical products with greater regularity. A CL is the use of a patented innovation that has been licensed by a state without the permission of the patent title holder. Skeptics doubted that many CLs would occur, given political pressure against CL activity and continued health system weakness in poor countries. The subsequent decade has seen little systematic assessment of the Doha Declaration's impact. METHODS AND FINDINGS: We assembled a database of all episodes in which a CL was publically entertained or announced by a WTO member state since 1995. Broad searches of CL activity were conducted using media, academic, and legal databases, yielding 34 potential CL episodes in 26 countries. Country- and product-specific searches were used to verify government participation, resulting in a final database of 24 verified CLs in 17 nations. We coded CL episodes in terms of outcome, national income, and disease group over three distinct periods of CL activity. Most CL episodes occurred between 2003 and 2005, involved drugs for HIV/AIDS, and occurred in upper-middle-income countries (UMICs. Aside from HIV/AIDS, few CL episodes involved communicable disease, and none occurred in least-developed or low-income countries. CONCLUSIONS: Given skepticism about the Doha Declaration's likely impact, we note the relatively high occurrence of CLs, yet CL activity has diminished markedly since 2006. While UMICs have high CL activity and strong incentives to use CLs compared to other countries, we note considerable countervailing pressures against CL use even in UMICs. We conclude that there is a low probability of continued CL activity. We highlight the need for further systematic

  5. 19 CFR 148.13 - Written declarations.

    Science.gov (United States)

    2010-04-01

    ...) When required. Unless an oral declaration is accepted under § 148.12, the declaration required of a..., HTSUS, for articles to be disposed of as bona fide gifts; or subheading 9804.00.40, HTSUS, for articles... passenger shall state either: (1) The price actually paid for the article in the currency of purchase, or...

  6. 32 CFR 701.43 - Fee declarations.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Fee declarations. 701.43 Section 701.43 National... OFFICIAL RECORDS AVAILABILITY OF DEPARTMENT OF THE NAVY RECORDS AND PUBLICATION OF DEPARTMENT OF THE NAVY DOCUMENTS AFFECTING THE PUBLIC FOIA Fees § 701.43 Fee declarations. Requesters should submit a fee...

  7. Short-Term Impact of Atmospheric Pollution on Fecundability

    Czech Academy of Sciences Publication Activity Database

    Slama, R.; Bottagisi, S.; Solanský, I.; Lepeule, J.; Giorgis-Allemand, L.; Šrám, Radim

    2013-01-01

    Roč. 24, č. 6 (2013), s. 871-879 ISSN 1044-3983 Institutional support: RVO:68378041 Keywords : particulate air-pollution * postneonatal infant-mortality * fertility Subject RIV: DN - Health Impact of the Environment Quality Impact factor: 6.178, year: 2013

  8. Impaired Emotional Declarative Memory Following Unilateral Amygdala Damage

    OpenAIRE

    Adolphs, Ralph; Tranel, Daniel; Denburg, Natalie

    2000-01-01

    Case studies of patients with bilateral amygdala damage and functional imaging studies of normal individuals have demonstrated that the amygdala plays a critical role in encoding emotionally arousing stimuli into long-term declarative memory. However, several issues remain poorly understood: the separate roles of left and right amygdala, the time course over which the amygdala participates in memory consolidation, and the type of knowledge structures it helps consolidate. We investigated thes...

  9. Procedural learning during declarative control.

    Science.gov (United States)

    Crossley, Matthew J; Ashby, F Gregory

    2015-09-01

    There is now abundant evidence that human learning and memory are governed by multiple systems. As a result, research is now turning to the next question of how these putative systems interact. For instance, how is overall control of behavior coordinated, and does learning occur independently within systems regardless of what system is in control? Behavioral, neuroimaging, and neuroscience data are somewhat mixed with respect to these questions. Human neuroimaging and animal lesion studies suggest independent learning and are mostly agnostic with respect to control. Human behavioral studies suggest active inhibition of behavioral output but have little to say regarding learning. The results of two perceptual category-learning experiments are described that strongly suggest that procedural learning does occur while the explicit system is in control of behavior and that this learning might be just as good as if the procedural system was controlling the response. These results are consistent with the idea that declarative memory systems inhibit the ability of the procedural system to access motor output systems but do not prevent procedural learning. (c) 2015 APA, all rights reserved).

  10. Enhancing effects of acute psychosocial stress on priming of non-declarative memory in healthy young adults.

    Science.gov (United States)

    Hidalgo, Vanesa; Villada, Carolina; Almela, Mercedes; Espín, Laura; Gómez-Amor, Jesús; Salvador, Alicia

    2012-05-01

    Social stress affects cognitive processes in general, and memory performance in particular. However, the direction of these effects has not been clearly established, as it depends on several factors. Our aim was to determine the impact of the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) reactivity to psychosocial stress on short-term non-declarative memory and declarative memory performance. Fifty-two young participants (18 men, 34 women) were subjected to the Trier Social Stress Task (TSST) and a control condition in a crossover design. Implicit memory was assessed by a priming test, and explicit memory was assessed by the Rey Auditory Verbal Learning Test (RAVLT). The TSST provoked greater salivary cortisol and salivary alpha-amylase (sAA) responses than the control task. Men had a higher cortisol response to stress than women, but no sex differences were found for sAA release. Stress was associated with an enhancement of priming but did not affect declarative memory. Additionally, the enhancement on the priming test was higher in those whose sAA levels increased more in response to stress (r(48) = 0.339, p = 0.018). Our results confirm an effect of acute stress on priming, and that this effect is related to SNS activity. In addition, they suggest a different relationship between stress biomarkers and the different memory systems.

  11. 29 CFR 18.804 - Hearsay exceptions; declarant unavailable.

    Science.gov (United States)

    2010-07-01

    ... believing that the declarant's death was imminent, concerning the cause or circumstances of what the... concerning the declarant's own birth, adoption, marriage, divorce, legitimacy, relationship by blood...

  12. Streamlining environmental product declarations: a stage model

    Science.gov (United States)

    Lefebvre, Elisabeth; Lefebvre, Louis A.; Talbot, Stephane; Le Hen, Gael

    2001-02-01

    General public environmental awareness and education is increasing, therefore stimulating the demand for reliable, objective and comparable information about products' environmental performances. The recently published standard series ISO 14040 and ISO 14025 are normalizing the preparation of Environmental Product Declarations (EPDs) containing comprehensive information relevant to a product's environmental impact during its life cycle. So far, only a few environmentally leading manufacturing organizations have experimented the preparation of EPDs (mostly from Europe), demonstrating its great potential as a marketing weapon. However the preparation of EPDs is a complex process, requiring collection and analysis of massive amounts of information coming from disparate sources (suppliers, sub-contractors, etc.). In a foreseeable future, the streamlining of the EPD preparation process will require product manufacturers to adapt their information systems (ERP, MES, SCADA) in order to make them capable of gathering, and transmitting the appropriate environmental information. It also requires strong functional integration all along the product supply chain in order to ensure that all the information is made available in a standardized and timely manner. The goal of the present paper is two fold: first to propose a transitional model towards green supply chain management and EPD preparation; second to identify key technologies and methodologies allowing to streamline the EPD process and subsequently the transition toward sustainable product development

  13. Mid-term financial impact of animal welfare improvements

    NARCIS (Netherlands)

    Gocsik, E.; Oude Lansink, A.G.J.M.; Saatkamp, H.W.

    2013-01-01

    This study used a stochastic bioeconomic simulation model to simulate the business and financial risk of different broiler production systems over a 5-yr period. Simulation analysis was conducted using the @Risk add-in in MS Excel. To compare the impact of different production systems on economic

  14. The role of sleep in human declarative memory consolidation.

    Science.gov (United States)

    Alger, Sara E; Chambers, Alexis M; Cunningham, Tony; Payne, Jessica D

    2015-01-01

    Through a variety of methods, researchers have begun unraveling the mystery of why humans spend one-third of their lives asleep. Though sleep likely serves multiple functions, it has become clear that the sleeping brain offers an ideal environment for solidifying newly learned information in the brain. Sleep , which comprises a complex collection of brain states, supports the consolidation of many different types of information. It not only promotes learning and memory stabilization, but also memory reorganization that can lead to various forms of insightful behavior. As this chapter will describe, research provides ample support for these crucial cognitive functions of sleep . Focusing on the declarative memory system in humans, we review the literature regarding the benefits of sleep for both neutral and emotionally salient declarative memory. Finally, we discuss the literature regarding the impact of sleep on emotion regulation.

  15. Spallation Neutron Source Accident Terms for Environmental Impact Statement Input

    Energy Technology Data Exchange (ETDEWEB)

    Devore, J.R.; Harrington, R.M.

    1998-08-01

    This report is about accidents with the potential to release radioactive materials into the environment surrounding the Spallation Neutron Source (SNS). As shown in Chap. 2, the inventories of radioactivity at the SNS are dominated by the target facility. Source terms for a wide range of target facility accidents, from anticipated events to worst-case beyond-design-basis events, are provided in Chaps. 3 and 4. The most important criterion applied to these accident source terms is that they should not underestimate potential release. Therefore, conservative methodology was employed for the release estimates. Although the source terms are very conservative, excessive conservatism has been avoided by basing the releases on physical principles. Since it is envisioned that the SNS facility may eventually (after about 10 years) be expanded and modified to support a 4-MW proton beam operational capability, the source terms estimated in this report are applicable to a 4-MW operating proton beam power unless otherwise specified. This is bounding with regard to the 1-MW facility that will be built and operated initially. See further discussion below in Sect. 1.2.

  16. The Analysis of a Real Life Declarative Process

    DEFF Research Database (Denmark)

    Debois, Søren; Slaats, Tijs

    2015-01-01

    This paper reports on a qualitative study of the use of declarative process notations used in a commercial setting. Specifically, we investigate the actual use of a system implemented in terms of DCR graphs for the Danish "Dreyer Foundation" by our industry partner Exformatics A/S. The study...... by the declarative model, and (2) use process discovery techniques to examine if a perfect-fitness flow-based model representing the main business constraints is in fact easy to come by. For (1), we find evidence in various forms, most notably an apparent change in best practices by end-users allowed by the model....... For (2), we find no such model. We leave as a challenge to the community the construction of a flow-based model adequately representing the business constraints and supporting all observed behaviour by the users, whether by hand or by mining....

  17. Signed reward prediction errors drive declarative learning.

    Directory of Open Access Journals (Sweden)

    Esther De Loof

    Full Text Available Reward prediction errors (RPEs are thought to drive learning. This has been established in procedural learning (e.g., classical and operant conditioning. However, empirical evidence on whether RPEs drive declarative learning-a quintessentially human form of learning-remains surprisingly absent. We therefore coupled RPEs to the acquisition of Dutch-Swahili word pairs in a declarative learning paradigm. Signed RPEs (SRPEs; "better-than-expected" signals during declarative learning improved recognition in a follow-up test, with increasingly positive RPEs leading to better recognition. In addition, classic declarative memory mechanisms such as time-on-task failed to explain recognition performance. The beneficial effect of SRPEs on recognition was subsequently affirmed in a replication study with visual stimuli.

  18. Signed reward prediction errors drive declarative learning.

    Science.gov (United States)

    De Loof, Esther; Ergo, Kate; Naert, Lien; Janssens, Clio; Talsma, Durk; Van Opstal, Filip; Verguts, Tom

    2018-01-01

    Reward prediction errors (RPEs) are thought to drive learning. This has been established in procedural learning (e.g., classical and operant conditioning). However, empirical evidence on whether RPEs drive declarative learning-a quintessentially human form of learning-remains surprisingly absent. We therefore coupled RPEs to the acquisition of Dutch-Swahili word pairs in a declarative learning paradigm. Signed RPEs (SRPEs; "better-than-expected" signals) during declarative learning improved recognition in a follow-up test, with increasingly positive RPEs leading to better recognition. In addition, classic declarative memory mechanisms such as time-on-task failed to explain recognition performance. The beneficial effect of SRPEs on recognition was subsequently affirmed in a replication study with visual stimuli.

  19. [The Helsinki Declaration: relativism and vulnerability].

    Science.gov (United States)

    Diniz, D; Corrêa, M

    2001-01-01

    The Helsinki Declaration is a crucial ethical landmark for clinical research involving human beings. Since the Declaration was issued, a series of revisions and modifications have been introduced into the original text, but they have not altered its humanist approach or its international force for regulating clinical research. A proposal for an extensive revision of the Declaration's underlying ethical principles has been debated for the past four years. If the proposal is approved, international clinical research involving human beings will be modified, further increasing the vulnerability of certain social groups. This article discusses the historical process involved in passing the Helsinki Declaration and the most recent debate on the new draft. The article analyzes the new text's social implications for underdeveloped countries, arguing for a political approach to the vulnerability concept.

  20. Measuring the Declared SDK Versions and Their Consistency with API Calls in Android Apps

    OpenAIRE

    Wu, Daoyuan; Liu, Ximing; Xu, Jiayun; Lo, David; Gao, Debin

    2017-01-01

    Android has been the most popular smartphone system, with multiple platform versions (e.g., KITKAT and Lollipop) active in the market. To manage the application's compatibility with one or more platform versions, Android allows apps to declare the supported platform SDK versions in their manifest files. In this paper, we make a first effort to study this modern software mechanism. Our objective is to measure the current practice of the declared SDK versions (which we term as DSDK versions aft...

  1. Analogous Mechanisms of Selection and Updating in Declarative and Procedural Working Memory: Experiments and a Computational Model

    Science.gov (United States)

    Oberauer, Klaus; Souza, Alessandra S.; Druey, Michel D.; Gade, Miriam

    2013-01-01

    The article investigates the mechanisms of selecting and updating representations in declarative and procedural working memory (WM). Declarative WM holds the objects of thought available, whereas procedural WM holds representations of what to do with these objects. Both systems consist of three embedded components: activated long-term memory, a…

  2. Impact of short-term severe accident management actions in a long-term perspective. Final Report

    International Nuclear Information System (INIS)

    2000-03-01

    The present systems for severe accident management are focused on mitigating the consequences of special severe accident phenomena and to reach a safe plant state. However, in the development of strategies and procedures for severe accident management, it is also important to consider the long-term perspective of accident management and especially to secure the safe state of the plant. The main reason for this is that certain short-term actions have an impact on the long-term scenario. Both positive and negative effects from short-term actions on the accident management in the long-term perspective have been included in this paper. Short-term actions are accident management measures taken within about 24 hours after the initiating event. The purpose of short-term actions is to reach a stable status of the plant. The main goal in the long-term perspective is to maintain the reactor in a stable state and prevent uncontrolled releases of activity. The purpose of this short Technical Note, deliberately limited in scope, is to draw attention to potential long-term problems, important to utilities and regulatory authorities, arising from the way a severe accident would be managed during the first hours. Its objective is to encourage discussions on the safest - and maybe also most economical - way to manage a severe accident in the long term by not making the situation worse through inappropriate short-term actions, and on the identification of short-term actions likely to make long-term management easier and safer. The Note is intended as a contribution to the knowledge base put at the disposal of Member countries through international collaboration. The scope of the work has been limited to a literature search. Useful further activities have been identified. However, there is no proposal, at this stage, for more detailed work to be undertaken under the auspices of the CSNI. Plant-specific applications would need to be developed by utilities

  3. Mothers with HIP - the short term and long-term impact, what is new?

    Science.gov (United States)

    Mecacci, Federico; Ottanelli, Serena; Petraglia, Felice

    2018-05-03

    Hyperglycemia is one of the most common medical conditions that women encounter during pregnancy and it is due to gestational diabetes (GDM) in the majority of cases [1]. GDM is associated with a higher incidence of maternal morbidity in pregnancy in term of hypertensive disorders/preclampsia and higher rate of cesarean delivery but also with long-term risk of type 2 diabetes and cardiovascular disease. Pregnancy can therefore be considered a stress test; diagnosis of HIP can unmask a preexisting susceptibility and consequently a future risk for type 2 diabetes and can be a useful marker of future cardiovascular risk. Postpartum follow up provides an excellent opportunity to implement healthy lifestyle behaviors to prevent or delay the development of diabetes or cardiovascular disease. The aim of the current review is to focus on short and long term maternal morbidity of HIP. Copyright © 2018. Published by Elsevier B.V.

  4. Fuel consumption: short term and long term price impacts per population type

    International Nuclear Information System (INIS)

    2011-01-01

    This report presents assessments of the price sensitivity of household fuel consumption. After a literature review on price-elasticity assessments and the use of pseudo-panels, the investigation analyses the deciding factors of the household fuel expense and its evolution between 1985 and 2006. It proposes a short term price-elasticity assessment based on the most recent survey, and also proposes price-elasticity assessments for sub-populations, notably in terms of income level or location (rural or urban areas)

  5. Geomagnetic Storms and Long-Term Impacts on Power Systems

    Energy Technology Data Exchange (ETDEWEB)

    Kirkham, Harold; Makarov, Yuri V.; Dagle, Jeffery E.; DeSteese, John G.; Elizondo, Marcelo A.; Diao, Ruisheng

    2011-12-31

    Pacific Northwest National Laboratory was commissioned to study the potential impact of a severe GIC event on the western U.S.-Canada power grid (referred to as the Western Interconnection). The study identified long transmission lines (length exceeding 150 miles) that did not include series capacitors. The basic assumption for the study is that a GIC is more likely to couple to long transmission lines, and that series capacitors would block the flow of the induced DC GIC. Power system simulations were conducted to evaluate impacts to the bulk power system if transformers on either end of these lines failed. The study results indicated that the Western Interconnection was not substantially at risk to GIC because of the relatively small number of transmission lines that met this criterion. This report also provides a summary of the Hydro-Québec blackout on March 13, 1989, which was caused by a GIC. This case study delves into the failure mechanisms of that event, lessons learned, and preventive measures that have been implemented to minimize the likelihood of its reoccurrence. Finally, the report recommends that the electric power industry consider the adoption of new protective relaying approaches that will prevent severe GIC events from catastrophically damaging transformers. The resulting changes may increase the likelihood of smaller disruptions but should prevent an unlikely yet catastrophic national-level event.

  6. The short-term impact of Ontario's generic pricing reforms.

    Directory of Open Access Journals (Sweden)

    Michael R Law

    Full Text Available Canadians pay amongst the highest generic drug prices in the world. In July 2010, the province of Ontario enacted a policy that halved reimbursement for generic drugs from the public drug plan, and substantially lowered prices for private purchases. We quantified the impact of this policy on overall generic drug expenditures in the province, and projected the impact in other provinces had they mimicked this pricing change.We used quarterly prescription generic drug dispensing data from the IMS-Brogan CompuScript Audit. We used the price per unit in both the pre- and post-policy period and two economics price indexes to estimate the expenditure reduction in Ontario. Further, we used the post-policy Ontario prices to estimate the potential reduction in other provinces.We estimate that total expenditure on generic drugs in Ontario during the second half of 2010 was between $181 and $194 million below what would be expected if prices had remained at pre-policy level. Over half of the reduction in spending was due to savings on just 10 generic ingredients. If other provinces had matched Ontario's prices, their expenditures over during the latter half of 2010 would have been $445 million lower.We found that if Ontario's pricing scheme were adopted nationally, overall spending on generic drugs in Canada would drop at least $1.28 billion annually--a 5% decrease in total prescription drug expenditure. Other provinces should seriously consider both changes to their generic drug prices and the use of more competitive bulk purchasing policies.

  7. 47 CFR 68.320 - Supplier's Declaration of Conformity.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Supplier's Declaration of Conformity. 68.320... Approval § 68.320 Supplier's Declaration of Conformity. (a) Supplier's Declaration of Conformity is a... Supplier's Declaration of Conformity attaches to all items subsequently marketed by the responsible party...

  8. 47 CFR 2.1072 - Limitation on Declaration of Conformity.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Limitation on Declaration of Conformity. 2.1072... Conformity § 2.1072 Limitation on Declaration of Conformity. (a) The Declaration of Conformity signifies that...'s rules. (b) A Declaration of Conformity by the responsible party is effective until a termination...

  9. Long-term impact of prematurity on postnatal neurohormonal regulation

    Directory of Open Access Journals (Sweden)

    M. I. Ziborova

    2016-01-01

    Full Text Available This article considers the psychophysiological and neuroendocrine differences characteristic of premature children, which are as a result of long-term perinatal consequences. Particular emphasis is laid on the effects of the hypothalamic-pituitary-adrenocortical stress system, the performance of which is reprogramed during complicated pregnancy, labor, and postnatal period under pain stress due to medical manipulations. Being extremely sensitive to all these exposures, the brain of a premature infant develops during activation of the stress system and takes on a few distinctive properties in addition to independent neuroanatomical distinctions due to premature birth. The altered neurohormonal patterns revealed in very prematurely born children and adolescents involve the regulation of mental processes, behavior, metabolism, and circadian rhythms (sleep-wake regulation, which differ from those in their maturely born peers. These cases allow learning and behavior problems and lower cognitive estimates to be considered in normally developing children born extremely prematurely who have also hormonal dysregulation.

  10. Event-Related Potential Correlates of Declarative and Non-Declarative Sequence Knowledge

    Science.gov (United States)

    Ferdinand, Nicola K.; Runger, Dennis; Frensch, Peter A.; Mecklinger, Axel

    2010-01-01

    The goal of the present study was to demonstrate that declarative and non-declarative knowledge acquired in an incidental sequence learning task contributes differentially to memory retrieval and leads to dissociable ERP signatures in a recognition memory task. For this purpose, participants performed a sequence learning task and were classified…

  11. Long-Term Hydrologic Impacts of Controlled Drainage Using DRAINMOD

    Science.gov (United States)

    Saadat, S.; Bowling, L. C.; Frankenberger, J.

    2017-12-01

    Controlled drainage is a management strategy designed to mitigate water quality issues caused by subsurface drainage but it may increase surface ponding and runoff. To improve controlled drainage system management, a long-term and broader study is needed that goes beyond the experimental studies. Therefore, the goal of this study was to parametrize the DRAINMOD field-scale, hydrologic model for the Davis Purdue Agricultural Center located in Eastern Indiana and to predict the subsurface drain flow and surface runoff and ponding at this research site. The Green-Ampt equation was used to characterize the infiltration, and digital elevation models (DEMs) were used to estimate the maximum depressional storage as the surface ponding parameter inputs to DRAINMOD. Hydraulic conductivity was estimated using the Hooghoudt equation and the measured drain flow and water table depths. Other model inputs were either estimated or taken from the measurements. The DRAINMOD model was calibrated and validated by comparing model predictions of subsurface drainage and water table depths with field observations from 2012 to 2016. Simulations based on the DRAINMOD model can increase understanding of the environmental and hydrological effects over a broader temporal and spatial scale than is possible using field-scale data and this is useful for developing management recommendations for water resources at field and watershed scales.

  12. Long-term impact of earthquakes on sleep quality.

    Science.gov (United States)

    Tempesta, Daniela; Curcio, Giuseppe; De Gennaro, Luigi; Ferrara, Michele

    2013-01-01

    We investigated the impact of the 6.3 magnitude 2009 L'Aquila (Italy) earthquake on standardized self-report measures of sleep quality (Pittsburgh Sleep Quality Index, PSQI) and frequency of disruptive nocturnal behaviours (Pittsburgh Sleep Quality Index-Addendum, PSQI-A) two years after the natural disaster. Self-reported sleep quality was assessed in 665 L'Aquila citizens exposed to the earthquake compared with a different sample (n = 754) of L'Aquila citizens tested 24 months before the earthquake. In addition, sleep quality and disruptive nocturnal behaviours (DNB) of people exposed to the traumatic experience were compared with people that in the same period lived in different areas ranging between 40 and 115 km from the earthquake epicenter (n = 3574). The comparison between L'Aquila citizens before and after the earthquake showed a significant deterioration of sleep quality after the exposure to the trauma. In addition, two years after the earthquake L'Aquila citizens showed the highest PSQI scores and the highest incidence of DNB compared to subjects living in the surroundings. Interestingly, above-the-threshold PSQI scores were found in the participants living within 70 km from the epicenter, while trauma-related DNBs were found in people living in a range of 40 km. Multiple regressions confirmed that proximity to the epicenter is predictive of sleep disturbances and DNB, also suggesting a possible mediating effect of depression on PSQI scores. The psychological effects of an earthquake may be much more pervasive and long-lasting of its building destruction, lasting for years and involving a much larger population. A reduced sleep quality and an increased frequency of DNB after two years may be a risk factor for the development of depression and posttraumatic stress disorder.

  13. Application of declarative modeling approaches for external events

    International Nuclear Information System (INIS)

    Anoba, R.C.

    2005-01-01

    Probabilistic Safety Assessments (PSAs) are increasingly being used as a tool for supporting the acceptability of design, procurement, construction, operation, and maintenance activities at Nuclear Power Plants. Since the issuance of Generic Letter 88-20 and subsequent IPE/IPEEE assessments, the NRC has issued several Regulatory Guides such as RG 1.174 to describe the use of PSA in risk-informed regulation activities. Most PSA have the capability to address internal events including internal floods. As the more demands are being placed for using the PSA to support risk-informed applications, there has been a growing need to integrate other eternal events (Seismic, Fire, etc.) into the logic models. Most external events involve spatial dependencies and usually impact the logic models at the component level. Therefore, manual insertion of external events impacts into a complex integrated fault tree model may be too cumbersome for routine uses of the PSA. Within the past year, a declarative modeling approach has been developed to automate the injection of external events into the PSA. The intent of this paper is to introduce the concept of declarative modeling in the context of external event applications. A declarative modeling approach involves the definition of rules for injection of external event impacts into the fault tree logic. A software tool such as the EPRI's XInit program can be used to interpret the pre-defined rules and automatically inject external event elements into the PSA. The injection process can easily be repeated, as required, to address plant changes, sensitivity issues, changes in boundary conditions, etc. External event elements may include fire initiating events, seismic initiating events, seismic fragilities, fire-induced hot short events, special human failure events, etc. This approach has been applied at a number of US nuclear power plants including a nuclear power plant in Romania. (authors)

  14. Declarative language design for interactive visualization.

    Science.gov (United States)

    Heer, Jeffrey; Bostock, Michael

    2010-01-01

    We investigate the design of declarative, domain-specific languages for constructing interactive visualizations. By separating specification from execution, declarative languages can simplify development, enable unobtrusive optimization, and support retargeting across platforms. We describe the design of the Protovis specification language and its implementation within an object-oriented, statically-typed programming language (Java). We demonstrate how to support rich visualizations without requiring a toolkit-specific data model and extend Protovis to enable declarative specification of animated transitions. To support cross-platform deployment, we introduce rendering and event-handling infrastructures decoupled from the runtime platform, letting designers retarget visualization specifications (e.g., from desktop to mobile phone) with reduced effort. We also explore optimizations such as runtime compilation of visualization specifications, parallelized execution, and hardware-accelerated rendering. We present benchmark studies measuring the performance gains provided by these optimizations and compare performance to existing Java-based visualization tools, demonstrating scalability improvements exceeding an order of magnitude.

  15. Pension Funds and the Impact of Switching Regulation on Long-Term Investment

    OpenAIRE

    Pedraza Morales, Alvaro Enrique; Fuentes, Olga; Searle, Pamela; Stewart, Fiona

    2017-01-01

    This paper looks at the impact of members' ability to switch pension fund provider and /or portfolio on the allocation of pension funds to long-term investments. The level of annual turnover in pension fund portfolios was compared with the amount of short-term investments (using government treasury bills and bank deposits as proxy). The investment regulations around switching and other mar...

  16. Declarative and non-declarative memory consolidation in children with sleep disorder

    Directory of Open Access Journals (Sweden)

    Eszter eCsabi

    2016-01-01

    Full Text Available Healthy sleep is essential in children’s cognitive, behavioral, and emotional development. However, remarkably little is known about the influence of sleep disorders on different memory processes in childhood. Such data could give us a deeper insight into the effect of sleep on the developing brain and memory functions and how the relationship between sleep and memory changes from childhood to adulthood. In the present study we examined the effect of sleep disorder on declarative and non-declarative memory consolidation by testing children with sleep-disordered breathing (SDB which is characterized by disrupted sleep structure. We used a story recall task to measure declarative memory and Alternating Serial Reaction Time (ASRT task to assess non-declarative memory. This task enables us to measure two aspects of non-declarative memory, namely general motor skill learning and sequence-specific learning. There were two sessions: a learning phase and a testing phase, separated by a 12-hour offline period with sleep. Our data showed that children with SDB exhibited a generally lower declarative memory performance both in the learning and testing phase; however, both the SDB and control groups exhibited retention of the previously recalled items after the offline period. Here we showed intact non-declarative consolidation in SDB group in both sequence-specific and general motor skill. These findings suggest that sleep disorders in childhood have a differential effect on different memory processes (online vs. offline and give us insight into how sleep disturbances affects developing brain.

  17. Declarative and Non-declarative Memory Consolidation in Children with Sleep Disorder.

    Science.gov (United States)

    Csábi, Eszter; Benedek, Pálma; Janacsek, Karolina; Zavecz, Zsófia; Katona, Gábor; Nemeth, Dezso

    2015-01-01

    Healthy sleep is essential in children's cognitive, behavioral, and emotional development. However, remarkably little is known about the influence of sleep disorders on different memory processes in childhood. Such data could give us a deeper insight into the effect of sleep on the developing brain and memory functions and how the relationship between sleep and memory changes from childhood to adulthood. In the present study we examined the effect of sleep disorder on declarative and non-declarative memory consolidation by testing children with sleep-disordered breathing (SDB) which is characterized by disrupted sleep structure. We used a story recall task to measure declarative memory and Alternating Serial Reaction time (ASRT) task to assess non-declarative memory. This task enables us to measure two aspects of non-declarative memory, namely general motor skill learning and sequence-specific learning. There were two sessions: a learning phase and a testing phase, separated by a 12 h offline period with sleep. Our data showed that children with SDB exhibited a generally lower declarative memory performance both in the learning and testing phase; however, both the SDB and control groups exhibited retention of the previously recalled items after the offline period. Here we showed intact non-declarative consolidation in SDB group in both sequence-specific and general motor skill. These findings suggest that sleep disorders in childhood have a differential effect on different memory processes (online vs. offline) and give us insight into how sleep disturbances affects developing brain.

  18. Evaluation of sanitary impact of urban air pollution. Agglomeration of Agen impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Agglomeration d'Agen impact a court et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    A health impact assessment of air pollution based on the I.n.V.S. guidelines has been conducted in Agen according to the regional Plan for the quality of air in the region of Aquitaine to assess short term effects of pollutants on morbidity (hospital admissions in 2002) and mortality (deaths in 2001), and long-term effects on mortality. This study is based on the four standardised steps of health risk assessment. It has been carried out in 8 cities homogeneously exposed, belonging to Agen agglomeration, representing a study population of 60,515 inhabitants. Atmospheric pollution indicators analysed are ozone and particles having diameter below 10 {mu}m. Short-term impact of atmospheric pollution has been estimated in term of mortality (total, cardiovascular and respiratory mortality) and on hospital intakes (for respiratory, cardiovascular and cardiac reasons) attributable to air pollution.Long-term impact was also assessed by the number of deaths due to atmospheric pollution. In 2001, the atmospheric pollution has directly been responsible in the studied area of 4 anticipated deaths, including 2 for cardiovascular reason. A decrease by 25% of the pollutants could allow avoiding 2 premature deaths per year among the 4 attributable to air pollution. Concerning long-term effects, a decrease by 5 {mu}g/m{sup 3} of the annual mean of P.M.10 would allow avoiding 11 premature deaths per year. The results of this study should be interpreted with care because of the limits of the method. However, they show that air pollution can have a health impact even in a small city like Agen, since everyone is exposed to air pollution. (author)

  19. Declarative interpretations of session-based concurrency

    DEFF Research Database (Denmark)

    Cano, Mauricio; Rueda, Camilo; López-Acosta, Hugo-Andrés

    2015-01-01

    Session-based concurrency is a type-based approach to the analysis of communication-intensive systems. Correct behavior in these systems may be specified in an operational or declarative style: the former defines how interactions are structured; the latter defines governing conditions...

  20. A declaration of eco-ethics

    Directory of Open Access Journals (Sweden)

    John Cairns Jr.

    2002-11-01

    Full Text Available Eco-ethics is the essential foundation for sustainable use of the planet. Such a foundation must consist of a series of value judgments to which humanity is committed. This declaration is a tentative attempt to provide some illustrative examples.

  1. The Universal Declaration of Human Rights

    Science.gov (United States)

    Landorf, Hilary

    2012-01-01

    A study of human rights prepares students for their role as global citizens and their study of practices in the world's countries that relate to the rights of human beings. Today, when one talks of human rights it is usually with reference to the 1948 Universal Declaration of Human Rights (UDHR). It is the task of teachers to give students the…

  2. Signed reward prediction errors drive declarative learning

    NARCIS (Netherlands)

    De Loof, E.; Ergo, K.; Naert, L.; Janssens, C.; Talsma, D.; van Opstal, F.; Verguts, T.

    2018-01-01

    Reward prediction errors (RPEs) are thought to drive learning. This has been established in procedural learning (e.g., classical and operant conditioning). However, empirical evidence on whether RPEs drive declarative learning–a quintessentially human form of learning–remains surprisingly absent. We

  3. A Formal Model For Declarative Workflows

    DEFF Research Database (Denmark)

    Mukkamala, Raghava Rao

    it as a general formal model for specification and execution of declarative, event-based business processes, as a generalization of a concurrency model, the classic event structures. The model allows for an intuitive operational semantics and mapping of execution state by a notion of markings of the graphs and we...

  4. State of emergency declared for Gran Sasso

    CERN Multimedia

    2003-01-01

    "On June 27th the Council of Ministers has declared the state of socioeconomic and environmental emergency in the territory of L'Aquila and Teramo, the provinces involved in the safety of the Gran Sasso system. The measure includes the INFN Gran Sasso National Laboratories, the high-way tunnels, the environment in general and water in particular" (1 page).

  5. Declarative Process Mining for DCR Graphs

    DEFF Research Database (Denmark)

    Debois, Søren; Hildebrandt, Thomas T.; Laursen, Paw Høvsgaard

    2017-01-01

    We investigate process mining for the declarative Dynamic Condition Response (DCR) graphs process modelling language. We contribute (a) a process mining algorithm for DCR graphs, (b) a proposal for a set of metrics quantifying output model quality, and (c) a preliminary example-based comparison...

  6. The Universal Declaration of Human Rights

    International Nuclear Information System (INIS)

    1968-01-01

    Human Rights Year, so designated by the United Nations, is now coming to an end. The full text of the Universal Declaration, proclaimed in 1946, is given as a reminder of its ideals. In 1966 Covenants for acceptance by States were drawn up and opened for signature. (author)

  7. The Amstersam declaration on fungal nomenclature

    DEFF Research Database (Denmark)

    Hawksworth, David L.; Crous, Pedro W.; Redhead, Scott A.

    2011-01-01

    The Amsterdam Declaration on Fungal Nomenclature was agreed at an international symposium convened in Amsterdam on 19–20 April 2011 under the auspices of the International Commission on the Taxonomy of Fungi (ICTF). The purpose of the symposium was to address the issue of whether or how the current...

  8. Stress enhances reconsolidation of declarative memory

    NARCIS (Netherlands)

    Bos, M.G.N.; Schuijer, J.; Lodestijn, F.; Beckers, T.; Kindt, M.

    2014-01-01

    Retrieval of negative emotional memories is often accompanied by the experience of stress. Upon retrieval, a memory trace can temporarily return into a labile state, where it is vulnerable to change. An unresolved question is whether post-retrieval stress may affect the strength of declarative

  9. Normal-range verbal-declarative memory in schizophrenia.

    Science.gov (United States)

    Heinrichs, R Walter; Parlar, Melissa; Pinnock, Farena

    2017-10-01

    Cognitive impairment is prevalent and related to functional outcome in schizophrenia, but a significant minority of the patient population overlaps with healthy controls on many performance measures, including declarative-verbal-memory tasks. In this study, we assessed the validity, clinical, and functional implications of normal-range (NR), verbal-declarative memory in schizophrenia. Performance normality was defined using normative data for 8 basic California Verbal Learning Test (CVLT-II; Delis, Kramer, Kaplan, & Ober, 2000) recall and recognition trials. Schizophrenia patients (n = 155) and healthy control participants (n = 74) were assessed for performance normality, defined as scores within 1 SD of the normative mean on all 8 trials, and assigned to normal- and below-NR memory groups. NR schizophrenia patients (n = 26) and control participants (n = 51) did not differ in general verbal ability, on a reading-based estimate of premorbid ability, across all 8 CVLT-II-score comparisons or in terms of intrusion and false-positive errors and auditory working memory. NR memory patients did not differ from memory-impaired patients (n = 129) in symptom severity, and both patient groups were significantly and similarly disabled in terms of functional status in the community. These results confirm a subpopulation of schizophrenia patients with normal, verbal-declarative-memory performance and no evidence of decline from higher premorbid ability levels. However, NR patients did not experience less severe psychopathology, nor did they show advantage in community adjustment relative to impaired patients. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  10. Trends in Compulsory Licensing of Pharmaceuticals Since the Doha Declaration: A Database Analysis

    Science.gov (United States)

    Beall, Reed; Kuhn, Randall

    2012-01-01

    Background It is now a decade since the World Trade Organization (WTO) adopted the “Declaration on the TRIPS Agreement and Public Health” at its 4th Ministerial Conference in Doha. Many anticipated that these actions would lead nations to claim compulsory licenses (CLs) for pharmaceutical products with greater regularity. A CL is the use of a patented innovation that has been licensed by a state without the permission of the patent title holder. Skeptics doubted that many CLs would occur, given political pressure against CL activity and continued health system weakness in poor countries. The subsequent decade has seen little systematic assessment of the Doha Declaration's impact. Methods and Findings We assembled a database of all episodes in which a CL was publically entertained or announced by a WTO member state since 1995. Broad searches of CL activity were conducted using media, academic, and legal databases, yielding 34 potential CL episodes in 26 countries. Country- and product-specific searches were used to verify government participation, resulting in a final database of 24 verified CLs in 17 nations. We coded CL episodes in terms of outcome, national income, and disease group over three distinct periods of CL activity. Most CL episodes occurred between 2003 and 2005, involved drugs for HIV/AIDS, and occurred in upper-middle-income countries (UMICs). Aside from HIV/AIDS, few CL episodes involved communicable disease, and none occurred in least-developed or low-income countries. Conclusions Given skepticism about the Doha Declaration's likely impact, we note the relatively high occurrence of CLs, yet CL activity has diminished markedly since 2006. While UMICs have high CL activity and strong incentives to use CLs compared to other countries, we note considerable countervailing pressures against CL use even in UMICs. We conclude that there is a low probability of continued CL activity. We highlight the need for further systematic evaluation of global

  11. BASEL III: long-term impact on economic performance and fluctuations

    OpenAIRE

    Paolo Angelini; Laurent Clerc; Vasco Cúrdia; Leonardo Gambacorta; Andrea Gerali; Alberto Locarno; Roberto Motto; Werner Roeger; Skander J. van den Heuvel; Jan Vlcek

    2011-01-01

    We assess the long-term economic impact of the new regulatory standards (the Basel III reform), answering the following questions: 1) What is the impact of the reform on longterm economic performance? 2) What is the impact of the reform on economic fluctuations? 3) What is the impact of the adoption of countercyclical capital buffers on economic fluctuations? The main results are the following: 1) Each percentage point increase in the capital ratio causes a median 0.09 percent decline in the ...

  12. IAEA receives Iraq's nuclear-related declaration

    International Nuclear Information System (INIS)

    2002-01-01

    Full text: The Director General of the International Atomic Energy Agency, Mohamed ElBaradei, announced that the IAEA received this evening, Sunday, 8 December 2002, at its Headquarters in Vienna, an approximately 2400 page declaration on Iraq's nuclear programme. The declaration consists of about 2100 pages in English and 300 pages in Arabic. The declaration was submitted by the Government of Iraq in response to paragraph 3 of Security Council resolution 1441 (8 November 2002), which requires Iraq to provide to UNMOVIC, the IAEA and to the Security Council, not later than 30 days of the date of that resolution, with 'currently accurate, full, and complete declaration of all aspects of its programmes to develop chemical, biological, and nuclear weapons, ballistic missiles, and other delivery systems... as well as all other chemical, biological, and nuclear programmes, including any which it claims are for purposes not related to weapon production or material'. 'The IAEA will immediately begin to assess this important new document,' said Mr. ElBaradei, 'including the painstaking and systematic cross-checking of the information provided by Iraq against information which the IAEA already has, information that it expects to receive from other Member States, as contemplated in resolution 1441, and results of past and present Agency verification activities.' Complete assessment of the declaration will be time consuming, particularly in light of the need to translate the 300 pages of Arabic text into English. However, the IAEA expects to be able to provide a preliminary analysis of the document to the Security Council within the next ten days, with a fuller assessment to be provided when it reports to the Council at the end of January. (IAEA)

  13. Long-term impacts of electricity generation systems. Draft technical report

    International Nuclear Information System (INIS)

    1998-01-01

    Estimation of health and environmental impacts in a distant future driven by current electricity generation systems is not a well established scientific field. This issue includes many uncertainties which are seen in many processes of the impact estimation such as valuation techniques of environmental impacts for a long-term, and technology choice and policy options for a long run. When the IAEA held the Technical Committee Meeting on Estimating and Comparing Risks from Energy Systems in the Far Future in October 1997 in Vienna, there were many questions raised up from the participants on these issues. The purpose of this document is to introduce typical discussions at the Meeting, and to give a guidance to the methodological approaches for the readers. The decision making process is not central to this technical document. The main issue explained in the document is the ways of presenting health and environmental impacts in a distant future for decision makers. The primarily targeted readers of this document are, therefore, experts who will make the impact assessment and document the results to governmental offices and/or representatives of general public. For those who further implement decision making study, several documents are available from the IAEA. (in preparation 29]). To provide an effective guidance to the methodological approaches, several issues which are currently recognized as typical examples of the impacts on future generations were chosen. Global climate change, nuclear and non-nuclear wastes, long lived radionuclides dispersing world-wide, land use, and resource depletion are briefly discussed to illustrate several technical difficulties in estimating the impacts in the far future. About technology choice, the discussions illustrated in this document are based on only marginal increase of currently available electricity production systems. For smooth introduction of currently available methodological approaches to readers, issues like future

  14. Recommendations for Enhancing Implementation of Additional Protocol Declarations

    International Nuclear Information System (INIS)

    Niina, Toshiaki; Nidaira, Kazuo; Aono, Yosuke

    2010-01-01

    Japan signed the Additional Protocol (hereafter, AP) in December 1998. The domestic law and regulation had been revised to implement the initial and annual declarations for the Agency and the Additional Protocol came into force in December 1999. Since initial declaration in 2000, Japan has submitted the annual declaration in every May. Until 2010, Japan has made 10 annual declarations. This paper gives recommendations to enhance implementation of Additional Protocol declarations based on 10-year experience in Japan and addresses the following: Current status of additional protocol declaration in Japan; Outline of processing method; AP Information Management System; Recommendations for improving quality of declaration. Preparation of additional protocol declaration in NMCC has been conducted in the course of contract with Japan Safeguards Office (hereafter, JSGO) for safeguards information treatment. (author)

  15. Evaluation of sanitary impact of the urban air pollution. Avignon area impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Zone d'Avignon impact a court et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    An health impact assessment of air pollution based on the I.n.V.S. guidelines has been conducted in Avignon according to the Regional Plan for the quality of air in the region of Provence Alpes Cote d'Azur. Short term impact of atmospheric pollution has been estimated in term of mortality (total, cardiovascular and respiratory mortality) and hospital admissions (for respiratory, cardiovascular and cardiac reasons) attributable to air pollution. Long-term impact was also assessed by the number of deaths due to atmospheric pollution. The study has been carried out in seven cities homogeneously exposed belonging to Vaucluse (Avignon, Le Pontet, Morieres les Avignon, Sorgues and Vedene) and two cities of the Gard department (les Angles and Villeneuve les Avignon) representing a study population of 153,624 inhabitants. Two period of study have been defined: period 1999-2000 for short and long term evaluations on the mortality and the year 2001 for the morbidity analysis. This study rests on methodological principles of E.I.S. (evaluation of sanitary impact) of urban air pollution whom methodology is in four steps: identification of dangers, exposure estimation, choice of exposure-risk relationship and risk characterisation. The pollutions indicators are built from four pollutants nitrogen dioxide, ozone, sulfur dioxide and PM{sub 10}. The exposure-risk relationships used come from epidemiological studies realised in general population, by preferring the multi centers studies and European ones. The number of deaths by year due to air pollution is 23, whom 10 by cardiovascular diseases, 2 by respiratory diseases. The most efficient scenario are these ones corresponding to air pollution decreases of 25% in the considered pollutant. About the long term sanitary benefits, the different scenario show that the European norm forecasted for 2005 is respected. The respect of the European norm expected for 2010 should allow to avoid 10 deaths on the totality of registered

  16. Regulatory impact of nuclear reactor accident source term assumptions. Technical report

    International Nuclear Information System (INIS)

    Pasedag, W.F.; Blond, R.M.; Jankowski, M.W.

    1981-06-01

    This report addresses the reactor accident source term implications on accident evaluations, regulations and regulatory requirements, engineered safety features, emergency planning, probabilistic risk assessment, and licensing practice. Assessment of the impact of source term modifications and evaluation of the effects in Design Basis Accident analyses, assuming a change of the chemical form of iodine from elemental to cesium iodide, has been provided. Engineered safety features used in current LWR designs are found to be effective for all postulated combinations of iodine source terms under DBA conditions. In terms of potential accident consequences, it is not expected that the difference in chemical form between elemental iodine and cesium iodide would be significant. In order to account for the current information on source terms, a spectrum of accident scenerios is discussed to realistically estimate the source terms resulting from a range of potential accident conditions

  17. Evaluation of sanitary impact of urban air pollution. Agglomeration of Bayonne impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Agglomeration de Bayonne impact a cour et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-15

    A health impact assessment of air pollution based on the I.n.V.S. guidelines has been conducted in Bayonne according to the regional Plan for the quality of air in the region of Aquitaine. It has been carried out in 16 cities homogeneously exposed, belonging to Bayonne agglomeration, representing a study population of 148,742 inhabitants. Atmospheric pollution indicators analyzed are ozone, nitrogen dioxide and particles having diameter below 10 {mu}m. Short-term impact of atmospheric pollution has been estimated in term of mortality (total, cardiovascular and respiratory mortality) and on hospital intakes (for respiratory, cardiovascular and cardiac reasons) attributable to air pollution. Long term impact was also assessed by the number of deaths due to atmospheric pollution. In 2001, the atmospheric pollution has directly been responsible in the studied area for 20 anticipated deaths. A decrease by 25% of the pollutants could allow avoiding half of the premature deaths and hospital intakes attributable to air pollution. Concerning long term effects, a decrease by 5 {mu}g/m{sup 3} of the annual mean of PM{sub 10} could allow avoiding 32 deaths per year. These results should be interpreted with care because of the limits of the method. However, they show that air pollution impact is non negligible even in a small agglomeration like Bayonne, since everyone is exposed to air pollution. They also suggest that a policy of atmospheric pollution reduction only based on not exceeding the standard levels would not have the expected benefits on the public health point of view. To decrease at the source the everyday and total pollutants emissions would be more efficient. (author)

  18. Evaluation of sanitary impact of urban air pollution. Agglomeration of Perigueux impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Agglomeration de Perigueux impact a court et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-15

    A health impact assessment of air pollution based on the I.n.V.S. guidelines has been conducted in Perigueux according to the regional Plan for the quality of air in the region of Aquitaine. It has been carried out in 5 cities homogeneously exposed, belonging to Perigueux agglomeration, representing a study population of 52,948 inhabitants. Atmospheric pollution indicators analysed are ozone, nitrogen dioxide and particles having diameter below 10 {mu}m. Short-term impact of atmospheric pollution has been estimated in term of mortality (total, cardiovascular and respiratory mortality) and on hospital intakes (for respiratory, cardiovascular and cardiac reasons) attributable to air pollution. Long term impact was also assessed by the number of deaths due to atmospheric pollution. In 2001, the atmospheric pollution has directly been responsible in the studied area for 5 anticipated deaths. A decrease by 25% of the pollutants could allow avoiding half of the premature deaths and hospital intakes attributable to air pollution. Concerning long term effects, a decrease by 5 {mu}g/m{sup 3} of the annual mean of P.M.10 could allow avoiding 10 deaths per year. These results should be interpreted with care because of the limits of the method. However, they show that air pollution can have an impact even in a small agglomeration like Perigueux, since everyone is exposed to air pollution. They also suggest that a policy of atmospheric pollution reduction only based on not exceeding the standard levels would not have the expected benefits on the public health point of view. To decrease at the source the every day and total pollutants emissions would be more efficient. (author)

  19. Evaluation of long term radiological impact on population close to remediated uranium mill tailings storages

    International Nuclear Information System (INIS)

    Kerouanton, David; Delgove, Laure

    2008-01-01

    A methodology is elaborated in order to evaluate the long term radiological impact of remediated uranium mill tailings storage. Different scenarios are chosen and modelled to cover future evolution of the tailings storages. Radiological impact is evaluated for different population such as adults and children living in the immediate vicinity or directly on the storage, road workers or walkers on the storage. Equation and methods are detailed. (author)

  20. Impact of short‐term, repeated water fasting on the weight of mice

    OpenAIRE

    Zahra Mishmast; Reza Rahimzadeh Oskuee; Amirali Aryan; Kamran Ghafarzadegan; Kiarash Ghazvini

    2014-01-01

    Introduction: Caloric restriction is a strategy applied for weight loss. Water fasting is a popular way for obesity treatment. However, little is known about the impact of water fasting on weight. Therefore, this study was conducted to investigate the effect of short-term, repeated water fasting on the weight of mice. Methods: In this study, the physiological effect of short-term, repeated water fasting on the weight of female mice was evaluated. At 6 weeks of age, mice were randomly assigned...

  1. Impact of source terms on distances to which reactor accident consequences occur

    International Nuclear Information System (INIS)

    Ostmeyer, R.M.

    1982-01-01

    Estimates of the distances over which reactor accident consequences might occur are important for development of siting criteria and for emergency response planning. This paper summarizes the results of a series of CRAC2 calculations performed to estimate these distances. Because of the current controversy concerning the magnitude of source terms for severe accidents, the impact of source term reductions upon distance estimates is also examined

  2. 2. The Amsterdam Declaration on fungal nomenclature

    DEFF Research Database (Denmark)

    Hawksworth, David L.; Crous, Pedro W.; Redhead, Scott A.

    2011-01-01

    The Amsterdam Declaration on Fungal Nomenclature was agreed at an international symposium convened in Amsterdam on 19-20 April 2011 under the auspices of the International Commission on the Taxonomy of Fungi (ICTF). The purpose of the symposium was to address the issue of whether or how the current...... to advise on the problem. The Declaration recognizes the need for an orderly transition to a single-name nomenclatural system for all fungi, and to provide mechanisms to protect names that otherwise then become endangered. That is, meaning that priority should be given to the first described name, except...... where there is a younger name in general use when the first author to select a name of a pleomorphic monophyletic genus is to be followed, and suggests controversial cases are referred to a body, such as the ICTF, which will report to the Committee for Fungi. If appropriate, the ICTF could be mandated...

  3. Declarative camera control for automatic cinematography

    Energy Technology Data Exchange (ETDEWEB)

    Christianson, D.B.; Anderson, S.E.; Li-wei He [Univ. of Washington, Seattle, WA (United States)] [and others

    1996-12-31

    Animations generated by interactive 3D computer graphics applications are typically portrayed either from a particular character`s point of view or from a small set of strategically-placed viewpoints. By ignoring camera placement, such applications fail to realize important storytelling capabilities that have been explored by cinematographers for many years. In this paper, we describe several of the principles of cinematography and show how they can be formalized into a declarative language, called the Declarative Camera Control Language (DCCL). We describe the application of DCCL within the context of a simple interactive video game and argue that DCCL represents cinematic knowledge at the same level of abstraction as expert directors by encoding 16 idioms from a film textbook. These idioms produce compelling animations, as demonstrated on the accompanying videotape.

  4. Evaluation of sanitary impact of urban air pollution. Agglomeration of Bordeaux impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Agglomeration de Bordeaux impact a cour et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-15

    A health impact assessment of air pollution based on the I.n.V.S. guidelines has been conducted in Bordeaux area. Atmospheric pollution indicators analyzed were ozone, nitrogen dioxide and particles having diameter below 10 {mu}m. Short term impact of atmospheric pollution has been estimated in term of mortality (total, cardiovascular and respiratory mortality) and hospital admissions (for respiratory, cardiovascular and cardiac reasons) attributable to air pollution. Long-term impact was also assessed by the number of deaths due to atmospheric pollution. The study has been carried out in 22 cities homogeneously exposed belonging to Bordeaux agglomeration, representing a study population of 604,238 inhabitants. In 2001, the atmospheric pollution has directly been responsible in the studied area of 56 anticipated deaths, including half for cardiovascular reasons and 7 for respiratory reasons. Regarding morbidity, 29 hospital admissions for respiratory disease were attributable to air pollution in 2002, including two-thirds among elderly people (aged 65 years and over). Further more, 81 hospitalizations for cardiovascular diseases that occurred in 2002 were attributable to air pollution, including 27 for cardiac reasons. A decrease by 25% of the pollutants could have allowed avoiding about half of the premature deaths and hospital intakes attributable to air pollution. Concerning long term effects, about 200 annual deaths are attributable to chronic exposure to air pollution, and a decrease by 5{mu}g/m{sup 3} of the annual mean of PM{sub 10} could allow avoiding half of these deaths. The results have to be interpreted with care because of the limits of the H.I.A. method. However, they show that air pollution has a non negligible impact even in a city like Bordeaux where target values are mostly respected. They also show that reducing air pollution can have a significant impact in term of mortality and morbidity. However, a policy of atmospheric pollution reduction

  5. Saul: Towards Declarative Learning Based Programming.

    Science.gov (United States)

    Kordjamshidi, Parisa; Roth, Dan; Wu, Hao

    2015-07-01

    We present Saul , a new probabilistic programming language designed to address some of the shortcomings of programming languages that aim at advancing and simplifying the development of AI systems. Such languages need to interact with messy, naturally occurring data, to allow a programmer to specify what needs to be done at an appropriate level of abstraction rather than at the data level, to be developed on a solid theory that supports moving to and reasoning at this level of abstraction and, finally, to support flexible integration of these learning and inference models within an application program. Saul is an object-functional programming language written in Scala that facilitates these by (1) allowing a programmer to learn, name and manipulate named abstractions over relational data; (2) supporting seamless incorporation of trainable (probabilistic or discriminative) components into the program, and (3) providing a level of inference over trainable models to support composition and make decisions that respect domain and application constraints. Saul is developed over a declaratively defined relational data model, can use piecewise learned factor graphs with declaratively specified learning and inference objectives, and it supports inference over probabilistic models augmented with declarative knowledge-based constraints. We describe the key constructs of Saul and exemplify its use in developing applications that require relational feature engineering and structured output prediction.

  6. Confidential Declaration of Family Situation (CDFS)

    CERN Document Server

    Human Resources Department

    2005-01-01

    The Confidential Declaration of Family Situation (CDFS) becomes a new computerized EDH form from October 2005 In accordance with Article R IV 1.17 of the Staff Regulations, Staff Members and Fellows, married or separated, must notify any changes in their spouse's income or health insurance cover in writing to CERN, within 30 calendar days of the change. This is necessary for the Organization to determine if a supplementary contribution is payable to the CERN Health Insurance Scheme (CHIS) for the spouse's coverage and, if so, the amount. Until now a paper form called « Confidential Declaration of Family Situation » (CDFS) was used for that purpose.  From early October 2005 the CDFS will be computerized for the whole Organization. Henceforth, any changes in a spouse's income or health insurance cover must be notified using EDH (Electronic Document Handling). Additionally, annual updates of the declaration will be required and will be requested by automatic e-mail. Early October an email will be sent to...

  7. Confidential Declaration of Family Situation (CDFS)

    CERN Multimedia

    Human Resources Department

    2005-01-01

    The Confidential Declaration of Family Situation (CDFS) becomes a new computerized EDH form from October 2005 In accordance with Article R IV 1.17 of the Staff Regulations, Staff Members and Fellows, married or separated, must notify any changes in their spouse's income or health insurance cover in writing to CERN, within 30 calendar days of the change. This is necessary for the Organization to determine if a supplementary contribution is payable to the CERN Health Insurance Scheme (CHIS) for the spouse's coverage and, if so, the amount. Until now a paper form called « Confidential Declaration of Family Situation » (CDFS) was used for that purpose.  From early October 2005 the CDFS will be computerized for the whole Organization. Henceforth, any changes in a spouse's income or health insurance cover must be notified using EDH (Electronic Document Handling). Additionally, annual updates of the declaration will be required and will be requested by automatic e-mail. Early October an email will be...

  8. IMPORTANT -Declaration of income for 2001-

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The local French tax authorities confirm that, in view of the particular procedure for income declaration for CERN members of the personnel, this year CERN income (as stated in the certificate of CERN remuneration provided by the Organization) may be exceptionally declared in either French Francs, or Euros (clearly specifying the currency selected). Practical information concerning the procedure for income declaration may be obtained at the following local information desks : Trésorerie de Gex: Tuesday 12 March 9 a.m. to 122 to 4 p.m. Trésoreriede Ferney: Monday 18 March 9 a.m. to 122 to 4 p.m. Trésoreriede Divonne: Thursday 21 March 9 a.m. to 122 to 4 p.m. French tax authorities have also organised the following information services:Web site Minitel: 3615 IR Service Vocal Server: 08 36 67 10 10 Telephone information: 08 20 32 42 52 Human Resources Division Tel. 72838

  9. Evaluation of urban air pollution impact. Brest and Nantes impact at long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Brest et Nantes impact a long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The assessment for Brest and Nantes of the health impact in 1999 of chronic exposure to air pollution relies on four stages: health outcome identification, the selection of exposure-response functions, exposure assessment and risk characterization. The study characterizes: - the health gain due to a 25% decrease in air pollution levels; - the expected health impact of a 15% rise in air pollution levels. The results give the number of deaths attributable to air pollution. As for the health gain, the gain in days of life expectancy is also calculated. The study for Brest relies on one single exposure-response function. Concerning Nantes, the air control network is more complete and allows to use four exposure-response functions. The health gain due to a 25% decrease in air pollution levels is interpreted as a prudent evaluation of the health impact of air pollution. The estimated number of deaths due to the impact is around 38 (23 - 53) for Brest and around 40 (14 - 65) for Nantes. It means a decrease in the lifespan of 48 (29 - 68) days for Brest and 51 (17 - 84) days for Nantes. The uncertainty about exposure evaluation, the use of American exposure-response functions and of strong hypotheses to calculate the lifespan reduction generate more errors and uncertainty than for short term health impact assessment. (author)

  10. Radioiodine source term and its potential impact on the use of potassium iodide

    International Nuclear Information System (INIS)

    Malinauskas, A.P.

    1982-01-01

    Information is presented concerning chemical forms of fission product iodine in the primary circuit; chemical forms of fission product iodine in the containment building; summary of iodine chemistry in light water reactor accidents; and impact of the radiodine source term on the potassium iodide issue

  11. Crop rotations and poultry litter impact dynamic soil chemical properties and soil biota long-term

    Science.gov (United States)

    Dynamic soil physiochemical interactions with conservation agricultural practices and soil biota are largely unknown. Therefore, this study aims to quantify long-term (12-yr) impacts of cover crops, poultry litter, crop rotations, and conservation tillage and their interactions on soil physiochemica...

  12. The Impact of a Death Education Program for Nurses in a Long-Term Care Hospital.

    Science.gov (United States)

    Fleming, Stephen; Brown, Isabel

    1983-01-01

    Assessed the impact of a death education program for nursing staff (N=130) of a long-term care institution. Analysis of nurses' chart entries (problem-oriented record format-POR) revealed a statistically significant increase from pre- to post-course in charting of patients' subjective state. (Author/JAC)

  13. Impact of Diabetes on Long-Term Outcome After Primary Angioplasty

    DEFF Research Database (Denmark)

    De Luca, Giuseppe; Dirksen, Maurits T; Spaulding, Christian

    2012-01-01

    Diabetes has been shown to be associated with worse survival and repeat target vessel revascularization (TVR) after primary angioplasty. The aim of the current study was to evaluate the impact of diabetes on long-term outcome in patients undergoing primary angioplasty treated with bare metal sten...

  14. The impact of health behaviour on long term sickness absence: results from DWECS/DREAM

    DEFF Research Database (Denmark)

    Christensen, Karl B; Lund, Thomas; Labriola, Merete

    2007-01-01

    Long term sickness absence (LTSA) is a major public health problem. We examined the impact of four, potentially modifiable, health behaviours, such as smoking, alcohol consumption, leisure time physical activity, and the associated variable of body mass index on the risk of subsequent LTSA...

  15. Long-term impact on work and private life after Guillain-Barre syndrome

    NARCIS (Netherlands)

    Bernsen, RAJAM; de Jager, AEJ; Schmitz, PIM; van der Meche, FGA

    2002-01-01

    Objective: To determine the long-term impact of Guillain-Barre syndrome (GBS) on work and private life of patients and their partners. Methods: Three to six years after the onset of GBS 150 patients who participated in the Dutch Guillain-Barre trial received a questionnaire specifically drafted for

  16. The Long-Term Economic Impact of in Utero and Postnatal Exposure to Malaria

    Science.gov (United States)

    Barreca, Alan I.

    2010-01-01

    I use an instrumental-variables identification strategy and historical data from the United States to estimate the long-term economic impact of in utero and postnatal exposure to malaria. My research design matches adults in the 1960 Decennial Census to the malaria death rate in their respective state and year of birth. To address potential…

  17. Faculty Development in Higher Education: Long-Term Impact of a Summer Teaching and Learning Workshop

    Science.gov (United States)

    Persellin, Diane; Goodrick, Terry

    2010-01-01

    Past participants of the Associated Colleges of the South Summer Teaching and Learning Workshop were surveyed to determine long-term impact of this type of professional development experience. Results indicate a large majority of participants across rank and academic discipline continued to view the workshop as effective and valued feedback from…

  18. The impact of health behaviour on long term sickness absence : Results from DWECS/DREAM

    NARCIS (Netherlands)

    Christensen, Karl B.; Lund, Thomas; Labriola, Merete; Bultmann, Ute; Villadsen, Ebbe

    Long term sickness absence (LTSA) is a major public health problem. We examined the impact of four, potentially modifiable, health behaviours, such as smoking, alcohol consumption, leisure time physical activity, and the associated variable of body mass index on the risk of subsequent LTSA. This was

  19. Assessing the Long-Term Impacts of Water Quality Outreach and Education Efforts on Agricultural Landowners

    Science.gov (United States)

    Jackson-Smith, Douglas B.; McEvoy, Jamie P.

    2011-01-01

    We assess the long-term effectiveness of outreach and education efforts associated with a water quality improvement project in a watershed located in northern Utah, USA. Conducted 15 years after the original project began, our research examines the lasting impacts of different extension activities on landowners' motivations to participate and…

  20. A Meta-Analysis of the Impact of Short-Term Sleep Deprivation on Cognitive Variables

    Science.gov (United States)

    Lim, Julian; Dinges, David F.

    2010-01-01

    A substantial amount of research has been conducted in an effort to understand the impact of short-term (less than 48 hr) total sleep deprivation (SD) on outcomes in various cognitive domains. Despite this wealth of information, there has been disagreement on how these data should be interpreted, arising in part because the relative magnitude of…

  1. Long-term impact of interferon beta-1b in patients with CIS

    DEFF Research Database (Denmark)

    Edan, G; Kappos, L; Montalbán, X

    2014-01-01

    OBJECTIVE: To examine the long-term impact of early treatment initiation of interferon beta-1b (IFNB1b, Betaferon/Betaseron) in patients with a first event suggestive of multiple sclerosis (MS). METHODS: In the original placebo-controlled phase of BENEFIT, patients were randomised to IFNB1b 250 μg...

  2. Learning Declarative and Procedural Knowledge via Video Lectures: Cognitive Load and Learning Effectiveness

    Science.gov (United States)

    Hong, Jianzhong; Pi, Zhongling; Yang, Jiumin

    2018-01-01

    Video lectures are being widely used in online and blended learning classes worldwide, and their learning effectiveness is becoming a focus of many educators and researchers. This study examined the cognitive load and learning effectiveness of video lectures in terms of the type of knowledge being taught (declarative or procedural) and instructor…

  3. An analysis on the short-term sectoral competitiveness impact of carbon tax in China

    International Nuclear Information System (INIS)

    Wang Xin; Li Ji Feng; Zhang Yaxiong

    2011-01-01

    Market-based instruments, particularly carbon tax, have recently drawn the attention of Chinese government by their cost-effective contribution to the achievement of China's climate targets. Most of the recent policy proposals have focused on its long-term impact. However, particularly for policy makers, both long term and short term effects of carbon tax would be necessary when determining tax rates. We provided a detailed analysis of short-term impacts of carbon tax on sectoral competitiveness in this paper. We divided China's economy into 36 sectors, based on its 2007 input-output table, in order to examine the ratio of carbon tax added costs to sector GDP. We were thus able to determine the impact level of a carbon tax on each sector. We then divided the sectoral trade impact into domestic competitiveness with regards to foreign imported products and international competitiveness external to the Chinese domestic market. We found that a high tax level (100 yuan/t CO 2 ) may necessitate compensatory measures to certain highly affected industries, and that a low tax rate (10 yuan/t CO 2 ) would generate few competitiveness problems for all industries and may therefore be considered as an appropriate starting point. - Highlights: → We study short-term sectoral competitiveness impact of carbon tax in China. → For each sector, we study its carbon cost, GDP share and trade intensity. → A high rate (100 yuan/t CO 2 ) may require compensatory measures to certain industries. → A low rate (10 yuan/t CO 2 ) would generate few competitiveness problems.

  4. The Significance of UNESCO’s Universal Declaration on the Human Genome & Human Rights

    Directory of Open Access Journals (Sweden)

    Shawn H.E. Harmon

    2005-03-01

    Full Text Available Modern medical research, particularly genetic research, is changing the nature of medicine. Concerns surrounding these changes and their potential negative impact on human rights led UNESCO to spearhead collaboration by experts in the creation of an international instrument intended to provide guidance for the promotion of bioethics and the protection of human rights in the genetic context. The result was the Universal Declaration of the Human Genome and Human Rights. This article briefly highlights the scientific and social setting into which the Declaration was injected. This is followed by a consideration of the drafting body (the IBC so as to assess whether UNESCO was the appropriate body to lead this project. The process by which the Declaration was created is also considered so as to assess whether it represents an example of ethical and democratic drafting. Finally, the substantive content of the Declaration is considered and measured against the pre-existing regime so as to assess whether it represents an intelligible and coherent response to the concerns raised capable of offering guidance now and into the future. By assessing these procedural and substantive matters, one can draw some tentative conclusions about the utility and significance of the Declaration.

  5. Declarative and procedural learning in children and adolescents with posterior fossa tumours

    Directory of Open Access Journals (Sweden)

    Casares Encarnación

    2006-03-01

    Full Text Available Abstract Background This quasi-experimental study was designed to assess two important learning types – procedural and declarative – in children and adolescents affected by posterior fossa tumours (astrocytoma vs. medulloblastoma, given that memory has an important impact on the child's academic achievement and personal development. Methods We had three groups: two clinical (eighteen subjects and one control (twelve subjects. The learning types in these groups were assessed by two experimental tasks evaluating procedural-implicit and declarative memory. A Serial Reaction-Time Task was used to measure procedural sequence learning, and the Spanish version 1 of the California Verbal Learning Test-Children's Version- CVLT- 2 to measure declarative-explicit learning. The learning capacity was assessed considering only the blocks that represent learning, and were compared with MANOVA in clinical and normal subjects. The Raven, simple reaction-time, finger-tapping test, and grooved pegboard tests were used to assess the overall functioning of subjects. The results were compared with those from a control group of the same age, and with Spanish norm-referenced tools where available Results The results indicate the absence of procedural-implicit learning in both clinical groups, whereas declarative-explicit learning is maintained in both groups. Conclusion The clinical groups showed a conservation of declarative learning and a clear impairment of procedural learning. The results support the role of the cerebellum in the early phase of procedural learning.

  6. Evaluation of sanitary impact of urban air pollution. Agglomeration of Pau impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Agglomeration de Pau impact a cour et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    A health impact assessment of air pollution based on the I.n.V.S. guidelines has been conducted in Pau according to the regional Plan for the quality of air in the region of Aquitaine. Short-term effects of pollutants on morbidity (hospital admissions in 2002) and mortality (deaths in 2001) have been estimated. Long-term effect on mortality was also assessed. This study is based on the four standardised steps of health risk assessment. It has been carried out in twenty-nine cities homogeneously exposed, belonging to Pau agglomeration, i.e. a study population of about 150,000 inhabitants. Atmospheric pollution indicators analysed are ozone, nitrogen dioxide, and particles having diameter below 10 {mu}m. Short-term impact of atmospheric pollution has been estimated in term of mortality (total, cardiovascular and respiratory mortality) and on hospital intakes (for respiratory, cardiovascular and cardiac reasons) attributable to air pollution. Long term impact was also assessed by the number of deaths due to atmospheric pollution. In 2001, the atmospheric pollution has directly been responsible in the studied area for 17 anticipated deaths, including 7 for cardiovascular reason and 2 for respiratory reason. Concerning morbidity, it generated 20 hospital admissions for cardiovascular reason in 2002, 11 for cardiac reason, and 7 for respiratory reason among elderly people. Regarding long-term health gains, an annually decrease according to the European standards levels of 2010 could allow avoiding 12 deaths per year, and a decrease by 30% of the pollutants could allow avoiding 33 premature deaths per year. This study shows that, even if the relative risks associated to air pollution are quite low, the number of attributable cases is non negligible since everyone is exposed to air pollution. It also shows that a policy of atmospheric pollution reduction only based on not exceeding the standard levels would not have the expected benefits on the public health point of view

  7. Evaluation of urban air pollution impact. Agglomeration of Toulon impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Agglomeration de Toulon impact a cour et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    A health impact assessment of air pollution based on the I.n.V.S. guidelines has been conducted in Toulon according to the Regional Plan for the quality of air in the region of Provence-Alpes-Cote d Azur. Short-term effects on morbidity (hospital admissions) and mortality and long-term effects on mortality were estimated. Four cities were included in the study area: Toulon, La Garde, La Seyne-sur-mer and La Valette-du-Var (population: 267.808 inhabitants. Two periods of study have been defined: 1999 for the mortality analysis and 2000 for the morbidity analysis and the long- term effects. For 1999, number of advanced deaths due to air pollution is around 84 for total mortality including 30 deaths due to cardio-vascular diseases and 10 deaths due to respiratory diseases. The different scenarios of air pollution reduction showed that the most effective ones are those which lead to reduce of 25% the mean of the involved pollutant. Regarding long-term effects, the different scenario showed that the respect of the European Community limits value for the year 2010 would allow to avoid 118 deaths over one year. Results showed that air pollution are even resulting in health effects for some levels of pollution lower than current French limits. The most effective actions should therefore associate reduction of the source emissions on a daily basis and decrease of the over-limits levels of pollution. (author)

  8. Long-Term Impacts Faced by Patients and Families After Harmful Healthcare Events.

    Science.gov (United States)

    Ottosen, Madelene J; Sedlock, Emily W; Aigbe, Aitebureme O; Bell, Sigall K; Gallagher, Thomas H; Thomas, Eric J

    2018-01-17

    Patients and families report experiencing a multitude of harms from medical errors resulting in physical, emotional, and financial hardships. Little is known about the duration and nature of these harms and the type of support needed to promote patient and family healing after such events. We sought to describe the long-term impacts (LTIs) reported by patients and family members who experienced harmful medical events 5 or more years ago. We performed a content analysis on 32 interviews originally conducted with 72 patients or family members about their views of the factors contributing to their self-reported harmful event. Interviews selected occurred 5 or more years after the harmful event and were grouped by time since event, 5 to 9 years (22 interviews) or 10 or more years (10 interviews) for analysis. We analyzed these interviews targeting spontaneous references of ongoing impacts experienced by the participants. Participants collectively described the following four LTIs: psychological, social/behavioral, physical, and financial. Most cited psychological impacts with half-reporting ongoing anger and vivid memories. More than half reported ongoing physical impacts and one-third experienced ongoing financial impacts. Long-term social and behavioral impacts such as alterations in lifestyle, self-identity, and healthcare seeking behaviors were the most highly reported. These patients and families experienced many profound LTIs after their harmful medical event. For some, these impacts evolved into secondary harms ongoing 10 years and more after the event. Our results draw attention to the persistent impacts patients and families may experience long after harmful events and the need for future research to understand and support affected patients and families.

  9. Short-Term Health Impact Assessment of Urban PM10 in Bejaia City (Algeria

    Directory of Open Access Journals (Sweden)

    Fatima Benaissa

    2016-01-01

    Full Text Available We used Health Impact Assessment (HIA to analyze the impact on a given population’s health outcomes in terms of all-causes mortality and respiratory and cardiovascular hospitalizations attributable to short-term exposure to particulate matter less than 10 μm diameter (PM10 in Bejaia city, for which health effects of air pollution have never been investigated. Two scenarios of PM10 reduction were considered: first, a scenario where the PM10 annual mean is decreased by 5 µg/m3, and then a scenario where this PM10 mean is decreased to 20 µg/m3 (World Health Organization annual air quality guideline (WHO-AQG. Annual mean level of PM10 (81.7 µg/m3 was calculated from objective measurements assessed in situ. Each year, about 4 and 55 deaths could be postponed with the first and the second scenarios successfully. Furthermore, decreasing PM10 annual mean by 5 µg/m3 would avoid 5 and 3 respiratory and cardiac hospitalizations, respectively, and not exceeding the PM10 WHO-AQG (20 µg/m3 would result in a potential gain of 36 and 23 per 100000 respiratory and cardiac hospitalizations, respectively. Lowering in current levels of PM10 has a nonnegligible impact in terms of public health that it is expected to be higher in the case of long-term effects.

  10. Making sense of site declarations: Canadian declarations under article 2.a. (iii) of the Additional Protocol

    International Nuclear Information System (INIS)

    Cameron, J.K.; Benjamin, R.; Ghosh, A.

    2001-01-01

    Full text: While this paper will provide an overview of Additional Protocol implementation activities in Canada, this paper will also deal with a specific, albeit important, component of Canada's initial declaration under the Additional Protocol: site definitions and declarations. A clear description of the problems, solutions and compromises in making site declarations across a variety of sites in Canada would provide a useful insight into the process as other States prepare to do the same. Through the Model Protocol Additional to Safeguards Agreements Between Member States and the International Atomic Energy Agency, provisions exist to fulfil a longstanding gap in the coverage of international safeguards. The success of these new provisions are dependent on the extent to which declarations balance the intent of expanded declarations and the practical difficulties in making such declarations. The prerogative to delineate site boundaries lies with the Member State. In doing so, four factors merit careful consideration. First, Article 18.b of the Additional Protocol draws connections between facility definition and site delineation. Under comprehensive safeguards, information on facilities has already been submitted to the IAEA specifying site layouts in the design information questionnaire. Consistency between the site layouts specifications of the design information and site definition under the Additional Protocol is important, as differences will lead to inconsistencies, which will have to be resolved during implementation. Second, while Article 18.b specified that specific essential services, co-located in close geographic proximity, should be considered as part of the same site, there are instances where site definition is complicated by close proximity of other, but separate, safeguarded facilities and the existence of services related, but not essentials according to the definitions of the Additional Protocol, to the site. Third, practical limitations come

  11. The short-term impacts of Earned Income Tax Credit disbursement on health.

    Science.gov (United States)

    Rehkopf, David H; Strully, Kate W; Dow, William H

    2014-12-01

    There are conflicting findings regarding long- and short-term effects of income on health. Whereas higher average income is associated with better health, there is evidence that health behaviours worsen in the short-term following income receipt.Prior studies revealing such negative short-term effects of income receipt focus on specific subpopulations and examine a limited set of health outcomes. The United States Earned Income Tax Credit (EITC) is an income supplement tied to work, and is the largest poverty reduction programme in the USA. We utilize the fact that EITC recipients typically receive large cash transfers in the months of February,March and April, in order to examine associated changes in health outcomes that can fluctuate on a monthly basis. We examine associations with 30 outcomes in the categories of diet, food security, health behaviours, cardiovascular biomarkers, metabolic biomarkers and infection and immunity among 6925 individuals from the U.S. National Health and Nutrition Survey. Our research design approximates a natural experiment,since whether individuals were sampled during treatment or non-treatment months is independent of social, demographic and health characteristics that do not vary with time. There are both beneficial and detrimental short-term impacts of income receipt.Although there are detrimental impacts on metabolic factors among women, most other impacts are beneficial, including those for food security, smoking and trying to lose weight. The short-term impacts of EITC income receipt are not universally health promoting, but on balance there are more health benefits than detriments.

  12. Evaluation of sanitary impact of urban air pollution. Montpellier area impact at short and long term; Evaluation de l'impact sanitaire de la pollution atmospherique urbaine. Zone de Montpellier impact a court et long terme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The assessment of the health impact of urban atmospheric pollution in Montpellier agglomeration has been carried out as part of the development of atmosphere protection plan. The study, based on the four standardised steps of health risk assessment, has two objectives. First of all, it aims at assessing the short-term impact of atmospheric pollution on mortality (total, cardiovascular and respiratory mortality) and on hospital intakes (for respiratory, cardiovascular and cardiac reasons). Second, the long-term impact is assessed by the number of deaths due to atmospheric pollution. On the other part, the computation of the expected health gain, as a function of different scenarios of atmospheric pollutants reduction, can allow to plan air quality improvement measures. The assessment of atmospheric pollution impact has been carried out in eleven cities, homogeneously exposed, belonging to Montpellier agglomeration (Castelnau-le-Lez, Clapiers, Le Cres, Grabels, Jacou, Juvignac, Montferrier-sur-Lez, Montpellier, Saint-Clement-de-Riviere, Saint- Jean-de-Vedas, Vendargues). It is based on the analysis of mortality figures during two years (1999 and 2000) and of hospital intakes during four years (from 1999 to 2002). The studied population is made up 288.059 inhabitants. Atmospheric pollution indicators analysed are ozone, nitrogen dioxide, sulphur dioxide and particles having diameter below 10 {mu}m. Every year, the atmospheric pollution is directly responsible in the studied area of 34 anticipated deaths, among including 13 for cardiovascular reason and 4 for respiratory reason. For morbidity, it generates every year 79 hospital admissions for cardiovascular reason, 15 for cardiac reason, 9 for respiratory reason for older than 65 years old people and 4 for 15-64 years old people. Older than 65 years old people are proportionally more impacted. These events could theoretically be avoided with pollution levels in the order of those reached the less polluted days. Health

  13. A long-term, integrated impact assessment of alternative building energy code scenarios in China

    International Nuclear Information System (INIS)

    Yu, Sha; Eom, Jiyong; Evans, Meredydd; Clarke, Leon

    2014-01-01

    China is the second largest building energy user in the world, ranking first and third in residential and commercial energy consumption. Beginning in the early 1980s, the Chinese government has developed a variety of building energy codes to improve building energy efficiency and reduce total energy demand. This paper studies the impact of building energy codes on energy use and CO 2 emissions by using a detailed building energy model that represents four distinct climate zones each with three building types, nested in a long-term integrated assessment framework GCAM. An advanced building stock module, coupled with the building energy model, is developed to reflect the characteristics of future building stock and its interaction with the development of building energy codes in China. This paper also evaluates the impacts of building codes on building energy demand in the presence of economy-wide carbon policy. We find that building energy codes would reduce Chinese building energy use by 13–22% depending on building code scenarios, with a similar effect preserved even under the carbon policy. The impact of building energy codes shows regional and sectoral variation due to regionally differentiated responses of heating and cooling services to shell efficiency improvement. - Highlights: • We assessed long-term impacts of building codes and climate policy using GCAM. • Building energy codes would reduce Chinese building energy use by 13–22%. • The impacts of codes on building energy use vary by climate region and sub-sector

  14. Stress enhances reconsolidation of declarative memory.

    Science.gov (United States)

    Bos, Marieke G N; Schuijer, Jantien; Lodestijn, Fleur; Beckers, Tom; Kindt, Merel

    2014-08-01

    Retrieval of negative emotional memories is often accompanied by the experience of stress. Upon retrieval, a memory trace can temporarily return into a labile state, where it is vulnerable to change. An unresolved question is whether post-retrieval stress may affect the strength of declarative memory in humans by modulating the reconsolidation process. Here, we tested in two experiments whether post-reactivation stress may affect the strength of declarative memory in humans. In both experiments, participants were instructed to learn neutral, positive and negative words. Approximately 24h later, participants received a reminder of the word list followed by exposure to the social evaluative cold pressor task (reactivation/stress group, nexp1=20; nexp2=18) or control task (reactivation/no-stress group, nexp1=23; nexp2=18). An additional control group was solely exposed to the stress task, without memory reactivation (no-reactivation/stress group, nexp1=23; nexp2=21). The next day, memory performance was tested using a free recall and a recognition task. In the first experiment we showed that participants in the reactivation/stress group recalled more words than participants in the reactivation/no-stress and no-reactivation/stress group, irrespective of valence of the word stimuli. Furthermore, participants in the reactivation/stress group made more false recognition errors. In the second experiment we replicated our observations on the free recall task for a new set of word stimuli, but we did not find any differences in false recognition. The current findings indicate that post-reactivation stress can improve declarative memory performance by modulating the process of reconsolidation. This finding contributes to our understanding why some memories are more persistent than others. Copyright © 2014. Published by Elsevier Ltd.

  15. Philosophiam profiteri or on Derrida's "declarative engagement"

    Directory of Open Access Journals (Sweden)

    Savić Mile V.

    2003-01-01

    Full Text Available In this paper the author reconstructs the meaning of Derrida's concept of "declarative engagement". He shows that Derrida revives the modern idea of the "engaged intellectual" and even develops it in a radical, prophetic/messianic form. The final consequence of such a position, in the opinion of the author, is a paradoxical coupling of political decisionism with social escapism, which renews in a specific way the nostalgia for the "heroic role" of the Marxist intellectual vanguard. This is a major reason for Derrida's popularity in Serbia, it is argued, but can also be taken as the starting point for an analysis of the problem of responsibility of engaged intellectuals.

  16. Warheads and Fissile Materials:Declarations and Counting

    International Nuclear Information System (INIS)

    Sutcliffe, W.G.

    1991-01-01

    This paper reviews some of the issues about verifying the dismantlement of nuclear warheads and controlling nuclear materials in the context of arms control objectives. It is asserted that information about the stockpiles of nuclear warheads and materials is necessary to analyze the impacts and verification requirements of arms control measures including warhead dismantlement and fissile material controls. It is proposed that the US and the Soviets engage in a series of declarations about their stockpiles of nuclear weapons and materials. It is also asserted that currently it is more important to verify that warheads are retired to safe, secure facilities than to verify their dismantlement. It is proposed that production of new or rebuilt warheads be limited to less than the number retired each year. Verifying the number of new and rebuilt warheads deployed and the number retired avoids many of the difficulties in verifying dismantlement and material controls

  17. Declaration of Helsinki, 2008: Implications for stakeholders in research

    Directory of Open Access Journals (Sweden)

    Puri K

    2009-01-01

    Full Text Available The Declaration of Helsinki (DoH was adopted by the World Medical Association (WMA in 1964, as a statement of ethical principles, to provide guidance to physicians and other participants in medical research involving human subjects. Having undergone several amendments, the most recent version was approved on 18 October 2008, by the WMA General Assembly at Seoul, South Korea, replacing all previous versions. This version highlights issues such as, participant safety, the need to include participants from otherwise underrepresented groups, clinical trial registration, post-study access, usage of data and human tissues, compensating participants with research-related injury, and usage of placebo. In this article, we discuss the major aspects of the 2008 version, including the impact of this version on all stakeholders in research, including, investigators, ethics committee members, sponsors, authors, editors, and reviewers.

  18. No Youth Left behind? The Long-Term Impact of Displacement on Young Workers

    OpenAIRE

    Hardoy, Ines; Schøne, Pål

    2013-01-01

    We investigate short- and long-term impacts on labour market outcomes of experiencing a displacement for young workers. The period under study is 2000–2009. The end of the observation period is characterised by a shrinking labour market, coinciding with the start of the financial crisis. The main merit of the study is the inclusion of a wide battery of dependent variables. In general we find sizeable short-term effect on both unemployment and wage-employment. Furthermore, the results indicate...

  19. The long-term problems of contaminated land: Sources, impacts and countermeasures

    Energy Technology Data Exchange (ETDEWEB)

    Baes, C.F. III

    1986-11-01

    This report examines the various sources of radiological land contamination; its extent; its impacts on man, agriculture, and the environment; countermeasures for mitigating exposures; radiological standards; alternatives for achieving land decontamination and cleanup; and possible alternatives for utilizing the land. The major potential sources of extensive long-term land contamination with radionuclides, in order of decreasing extent, are nuclear war, detonation of a single nuclear weapon (e.g., a terrorist act), serious reactor accidents, and nonfission nuclear weapons accidents that disperse the nuclear fuels (termed ''broken arrows'').

  20. The long-term problems of contaminated land: Sources, impacts and countermeasures

    International Nuclear Information System (INIS)

    Baes, C.F. III.

    1986-11-01

    This report examines the various sources of radiological land contamination; its extent; its impacts on man, agriculture, and the environment; countermeasures for mitigating exposures; radiological standards; alternatives for achieving land decontamination and cleanup; and possible alternatives for utilizing the land. The major potential sources of extensive long-term land contamination with radionuclides, in order of decreasing extent, are nuclear war, detonation of a single nuclear weapon (e.g., a terrorist act), serious reactor accidents, and nonfission nuclear weapons accidents that disperse the nuclear fuels (termed ''broken arrows'')

  1. Understanding long-term variations in an elephant piosphere effect to manage impacts.

    Directory of Open Access Journals (Sweden)

    Marietjie Landman

    Full Text Available Surface water availability is a key driver of elephant impacts on biological diversity. Thus, understanding the spatio-temporal variations of these impacts in relation to water is critical to their management. However, elephant piosphere effects (i.e. the radial pattern of attenuating impact are poorly described, with few long-term quantitative studies. Our understanding is further confounded by the complexity of systems with elephant (i.e. fenced, multiple water points, seasonal water availability, varying population densities that likely limit the use of conceptual models to predict these impacts. Using 31 years of data on shrub structure in the succulent thickets of the Addo Elephant National Park, South Africa, we tested elephant effects at a single water point. Shrub structure showed a clear sigmoid response with distance from water, declining at both the upper and lower limits of sampling. Adjacent to water, this decline caused a roughly 300-m radial expansion of the grass-dominated habitats that replace shrub communities. Despite the clear relationship between shrub structure and ecological functioning in thicket, the extent of elephant effects varied between these features with distance from water. Moreover, these patterns co-varied with other confounding variables (e.g. the location of neighboring water points, which limits our ability to predict such effects in the absence of long-term data. We predict that elephant have the ability to cause severe transformation in succulent thicket habitats with abundant water supply and elevated elephant numbers. However, these piosphere effects are complex, suggesting that a more integrated understanding of elephant impacts on ecological heterogeneity may be required before water availability is used as a tool to manage impacts. We caution against the establishment of water points in novel succulent thicket habitats, and advocate a significant reduction in water provisioning at our study site

  2. Understanding long-term variations in an elephant piosphere effect to manage impacts.

    Science.gov (United States)

    Landman, Marietjie; Schoeman, David S; Hall-Martin, Anthony J; Kerley, Graham I H

    2012-01-01

    Surface water availability is a key driver of elephant impacts on biological diversity. Thus, understanding the spatio-temporal variations of these impacts in relation to water is critical to their management. However, elephant piosphere effects (i.e. the radial pattern of attenuating impact) are poorly described, with few long-term quantitative studies. Our understanding is further confounded by the complexity of systems with elephant (i.e. fenced, multiple water points, seasonal water availability, varying population densities) that likely limit the use of conceptual models to predict these impacts. Using 31 years of data on shrub structure in the succulent thickets of the Addo Elephant National Park, South Africa, we tested elephant effects at a single water point. Shrub structure showed a clear sigmoid response with distance from water, declining at both the upper and lower limits of sampling. Adjacent to water, this decline caused a roughly 300-m radial expansion of the grass-dominated habitats that replace shrub communities. Despite the clear relationship between shrub structure and ecological functioning in thicket, the extent of elephant effects varied between these features with distance from water. Moreover, these patterns co-varied with other confounding variables (e.g. the location of neighboring water points), which limits our ability to predict such effects in the absence of long-term data. We predict that elephant have the ability to cause severe transformation in succulent thicket habitats with abundant water supply and elevated elephant numbers. However, these piosphere effects are complex, suggesting that a more integrated understanding of elephant impacts on ecological heterogeneity may be required before water availability is used as a tool to manage impacts. We caution against the establishment of water points in novel succulent thicket habitats, and advocate a significant reduction in water provisioning at our study site, albeit with greater

  3. Assessing the short term impact of air pollution on mortality: a matching approach.

    Science.gov (United States)

    Baccini, Michela; Mattei, Alessandra; Mealli, Fabrizia; Bertazzi, Pier Alberto; Carugno, Michele

    2017-02-10

    The opportunity to assess short term impact of air pollution relies on the causal interpretation of the exposure-response association. However, up to now few studies explicitly faced this issue within a causal inference framework. In this paper, we reformulated the problem of assessing the short term impact of air pollution on health using the potential outcome approach to causal inference. We considered the impact of high daily levels of particulate matter ≤10 μm in diameter (PM 10 ) on mortality within two days from the exposure in the metropolitan area of Milan (Italy), during the period 2003-2006. Our research focus was the causal impact of a hypothetical intervention setting daily air pollution levels under a pre-fixed threshold. We applied a matching procedure based on propensity score to estimate the total number of attributable deaths (AD) during the study period. After defining the number of attributable deaths in terms of difference between potential outcomes, we used the estimated propensity score to match each high exposure day, namely each day with a level of exposure higher than 40 μg/m 3 , with a day with similar background characteristics but a level of exposure lower than 40 μg/m 3 . Then, we estimated the impact by comparing mortality between matched days. During the study period daily exposures larger than 40 μg/m 3 were responsible for 1079 deaths (90% CI: 116; 2042). The impact was more evident among the elderly than in the younger age classes. Exposures ≥ 40 μg/m 3 were responsible, among the elderly, for 1102 deaths (90% CI: 388, 1816), of which 797 from cardiovascular causes and 243 from respiratory causes. Clear evidence of an impact on respiratory mortality was found also in the age class 65-74, with 87 AD (90% CI: 11, 163). The propensity score matching turned out to be an appealing method to assess historical impacts in this field, which guarantees that the estimated total number of AD can be derived directly as sum

  4. Norway spruce crown structure changes under long-term multiple stress impact in Central European Mts

    Czech Academy of Sciences Publication Activity Database

    Moravec, Ivo; Cudlín, Pavel; Polák, T.

    2003-01-01

    Roč. 22, Suppl. 1 (2003), s. 252-255 ISSN 1335-342X. [Long Term Air Pollution Effect on Forest Ecosystems (International Meeting for Specialists in Air Pollution Effects on Forest Ecosystems)/20./. Zvolen, 30.08.2002-01.09.2002] R&D Projects: GA MŠk OK 355 Institutional research plan: CEZ:AV0Z6087904 Keywords : Norway spruce * crown transformation * tree status Subject RIV: EH - Ecology, Behaviour Impact factor: 0.100, year: 2003

  5. Environmental Issues in the Power Sector : Long-Term Impacts and Policy Options for Karnataka

    OpenAIRE

    World Bank

    2004-01-01

    This study of the long-term environmental impacts and policy options for power sector development in Karnataka, is one of a series undertaken by the Bank, in cooperation with the Government of India and state governments. It is a follow-up to the broader study Environmental Issues in the Power Sector (EIPS) (ESMAP/World Bank 1998), and the general methodology developed for EIPS, is used fo...

  6. The Near-Term Impacts of Carbon Mitigation Policies on Manufacturing Industries

    OpenAIRE

    Morgenstern, Richard; Shih, Jhih-Shyang; Ho, Mun; Zhang, Xuehua

    2002-01-01

    Who will pay for new policies to reduce carbon dioxide and other greenhouse gas emissions in the United States? This paper considers a slice of the question by examining the near-term impact on domestic manufacturing industries of both upstream (economy-wide) and downstream (electric power industry only) carbon mitigation policies. Detailed Census data on the electricity use of four-digit manufacturing industries is combined with input-output information on interindustry purchases to paint a ...

  7. The Long-term Impact of Birth Order on Health and Educational Attainment

    OpenAIRE

    Barclay, Kieron

    2014-01-01

    This doctoral thesis examines the long-term impact of birth order on health, and educational attainment. Swedish register data is used to link individuals to their siblings, thereby allowing members of the sibling group to be compared to one another. This thesis consists of an introductory chapter summarizing empirical research on the relationship between birth order and educational attainment, intelligence, health, and personality, as well the theoretical frameworks that have been developed ...

  8. The long term impact of the 1918 influenza pandemic in Norway

    OpenAIRE

    Bakken, Magnus Røthe; Husøy, Sigrid Johanne

    2016-01-01

    A growing literature show the negative effect of prenatal health shocks on childhood and adult outcomes. Several studies exploit disease outbreaks to find causal effects of in utero exposure on various outcomes. We build on the existing literature by applying theories of in utero health effects to Norwegian data. This thesis uses the 1918 Spanish Influenza pandemic as a natural experiment to investigate the impact of prenatal health shock on various long term outcomes in Norway...

  9. Long term impacts of nuclear energy: On which purpose do we try to evaluate them?

    International Nuclear Information System (INIS)

    Beutler, Didier

    1998-01-01

    The indicators and the time limits for evaluation of the long term impacts of nuclear energy depend on the purpose: assessing the total cost of electricity generation; comparing different nuclear strategies; responding to public acceptance concerns; elaborating and selecting the most sustainable energy systems. Indicators that can be used are: consumption of non renewable resources; concentrations in the environment; individual exposures; collective dose; potential radiotoxicity. For all of them predicted or conditional values can be applied

  10. The Long-Term Economic Impact of In Utero and Postnatal Exposure to Malaria

    OpenAIRE

    Alan Barreca

    2009-01-01

    I use an instrumental-variables identification strategy and historical data from the United States to estimate the long-term economic impact of in utero and postnatal exposure to malaria. My research design matches adults in the 1960 Decennial Census to the malaria death rate in their respective state and year of birth. To address potential omitted variables bias and measurement-error bias, I use variation in "malaria-ideal" temperatures to instrument for malaria exposure. My estimates indica...

  11. Impact of higher twist terms on the analysis of scaling violation

    International Nuclear Information System (INIS)

    Barnett, R.M.

    1979-09-01

    A critical discussion is given of analyses of scaling violation in deep-inelastic scattering in the context of QCD. Several possible approaches are examined. Higher twist contributions are defined, and it is shown that they can have a crucial impact on tests of QCD. Higher twist terms can dramatically affect R = sigma/sub L//sigma/sub T/. QCD may be harder to test than previously realized. 17 references

  12. Declarative flow control for distributed instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Parvin, Bahram; Taylor, John; Fontenay, Gerald; Callahan, Daniel

    2001-06-01

    We have developed a 'microscopy channel' to advertise a unique set of on-line scientific instruments and to let users join a particular session, perform an experiment, collaborate with other users, and collect data for further analysis. The channel is a collaborative problem solving environment (CPSE) that allows for both synchronous and asynchronous collaboration, as well as flow control for enhanced scalability. The flow control is a declarative feature that enhances software functionality at the experimental scale. Our testbed includes several unique electron and optical microscopes with applications ranging from material science to cell biology. We have built a system that leverages current commercial CORBA services, Web Servers, and flow control specifications to meet diverse requirements for microscopy and experimental protocols. In this context, we have defined and enhanced Instrument Services (IS), Exchange Services (ES), Computational Services (CS), and Declarative Services (DS) that sit on top of CORBA and its enabling services (naming, trading, security, and notification) IS provides a layer of abstraction for controlling any type of microscope. ES provides a common set of utilities for information management and transaction. CS provides the analytical capabilities needed for online microscopy. DS provides mechanisms for flow control for improving the dynamic behavior of the system.

  13. Declarative Modeling for Production Order Portfolio Scheduling

    Directory of Open Access Journals (Sweden)

    Banaszak Zbigniew

    2014-12-01

    Full Text Available A declarative framework enabling to determine conditions as well as to develop decision-making software supporting small- and medium-sized enterprises aimed at unique, multi-project-like and mass customized oriented production is discussed. A set of unique production orders grouped into portfolio orders is considered. Operations executed along different production orders share available resources following a mutual exclusion protocol. A unique product or production batch is completed while following a given activity’s network order. The problem concerns scheduling a newly inserted project portfolio subject to constraints imposed by a multi-project environment The answers sought are: Can a given project portfolio specified by its cost and completion time be completed within the assumed time period in a manufacturing system in hand? Which manufacturing system capability guarantees the completion of a given project portfolio ordered under assumed cost and time constraints? The considered problems regard finding a computationally effective approach aimed at simultaneous routing and allocation as well as batching and scheduling of a newly ordered project portfolio subject to constraints imposed by a multi-project environment. The main objective is to provide a declarative model enabling to state a constraint satisfaction problem aimed at multi-project-like and mass customized oriented production scheduling. Multiple illustrative examples are discussed.

  14. Cognitive foundations of organizational learning: re-introducing the distinction between declarative and non-declarative knowledge

    Science.gov (United States)

    Kump, Barbara; Moskaliuk, Johannes; Cress, Ulrike; Kimmerle, Joachim

    2015-01-01

    Contemporary research into socio-cognitive foundations of organizational learning tends to disregard the distinction between declarative and non-declarative knowledge. By reviewing the literature from organizational learning research and cognitive psychology we explain that this distinction is crucial. We describe the foundations of organizational learning by referring to models that consider the interplay between individual and collective knowledge-related processes in organizations. We highlight the existence of a research gap resulting from the finding that these approaches have widely neglected the existence of different types of knowledge. We then elaborate on characteristics of declarative and non-declarative knowledge in general, consider organizations as structures of distributed cognition, and discuss the relationship between organizational knowledge and practice. Subsequently, we examine the role of declarative and non-declarative knowledge in the context of organizational learning. Here, we analyze (1) the cognitive and social mechanisms underlying the development of declarative and non-declarative knowledge within structures of distributed cognition; and (2) the relationship between alterations in declarative and non-declarative types of knowledge on the one hand and changes in organizational practice on the other. Concluding, we discuss implications of our analysis for organizational learning research. We explain how our integrative perspective may offer starting points for a refined understanding of the sub-processes involved in organizational learning and unlearning and may support a better understanding of practical problems related to organizational learning and change. PMID:26483739

  15. Cognitive foundations of organizational learning: re-introducing the distinction between declarative and non-declarative knowledge.

    Science.gov (United States)

    Kump, Barbara; Moskaliuk, Johannes; Cress, Ulrike; Kimmerle, Joachim

    2015-01-01

    Contemporary research into socio-cognitive foundations of organizational learning tends to disregard the distinction between declarative and non-declarative knowledge. By reviewing the literature from organizational learning research and cognitive psychology we explain that this distinction is crucial. We describe the foundations of organizational learning by referring to models that consider the interplay between individual and collective knowledge-related processes in organizations. We highlight the existence of a research gap resulting from the finding that these approaches have widely neglected the existence of different types of knowledge. We then elaborate on characteristics of declarative and non-declarative knowledge in general, consider organizations as structures of distributed cognition, and discuss the relationship between organizational knowledge and practice. Subsequently, we examine the role of declarative and non-declarative knowledge in the context of organizational learning. Here, we analyze (1) the cognitive and social mechanisms underlying the development of declarative and non-declarative knowledge within structures of distributed cognition; and (2) the relationship between alterations in declarative and non-declarative types of knowledge on the one hand and changes in organizational practice on the other. Concluding, we discuss implications of our analysis for organizational learning research. We explain how our integrative perspective may offer starting points for a refined understanding of the sub-processes involved in organizational learning and unlearning and may support a better understanding of practical problems related to organizational learning and change.

  16. Does the cholinesterase inhibitor, donepezil, benefit both declarative and non-declarative processes in mild to moderate Alzheimer's disease?

    Science.gov (United States)

    Winstein, Carolee J; Bentzen, Kirk R; Boyd, Lara; Schneider, Lon S

    2007-07-01

    Previous research suggests separate neural networks for implicit (non-declarative) and explicit (declarative) memory processes. A core cognitive impairment in mild to moderate Alzheimer's disease (AD) is a pronounced declarative memory and learning deficit with relative preservation of non-declarative memory. Cholinesterase inhibitors has been purported to enhance cognitive function, and previous clinical trials consistently showed that donepezil, a reversible inhibitor of acetylcholinesterase (AChE), led to statistically significant improvements in cognition and patient function. This prospective pilot study is a randomized, double blind, placebo-controlled clinical trial investigating 10 patients with AD. Our purpose was to examine the relationship between declarative and non-declarative capability with particular emphasis on implicit sequence learning. Patients were assessed at baseline and again at 4-weeks. After participants' baseline data were obtained, each was double-blindly randomized to one of two groups: donepezil or placebo. At baseline participants were tested with two outcome measures (Serial Reaction Time Task, Alzheimer's Disease Assessment Scale-Cognitive Subscale). Participants were given either 5 mg donepezil or an identically appearing placebo to be taken nightly for 4 weeks (28 tablets), and then retested. The donepezil group demonstrated a greater likelihood of increases in both non-declarative and declarative processes. The placebo group was mixed without clearly definable trends or patterns. When the data were examined for coincidental changes in the two outcome measures together they are suggestive of a benefit from donepezil treatment for non-declarative and declarative processes.

  17. The Long-Term Impact of Service-Learning on Graduates' Civic Engagement and Career Exploration in Hong Kong

    Science.gov (United States)

    Hok-ka, Carol Ma; Wing-fung, Chad Chan; Cheung-ming, Alfred Chan

    2016-01-01

    Service-learning (SL) is a relatively new pedagogy in Hong Kong and so far, no study of SL's long-term impact in Hong Kong exists. To explore SL's impacts on Hong Kong students, researchers conducted a quantitative study to compare graduates with SL experience to graduates without SL experience in terms of three domains: (1) adaptability, brain…

  18. A shared resource between declarative memory and motor memory

    Science.gov (United States)

    Keisler, Aysha; Shadmehr, Reza

    2010-01-01

    The neural systems that support motor adaptation in humans are thought to be distinct from those that support the declarative system. Yet, during motor adaptation changes in motor commands are supported by a fast adaptive process that has important properties (rapid learning, fast decay) that are usually associated with the declarative system. The fast process can be contrasted to a slow adaptive process that also supports motor memory, but learns gradually and shows resistance to forgetting. Here we show that after people stop performing a motor task, the fast motor memory can be disrupted by a task that engages declarative memory, but the slow motor memory is immune from this interference. Furthermore, we find that the fast/declarative component plays a major role in the consolidation of the slow motor memory. Because of the competitive nature of declarative and non-declarative memory during consolidation, impairment of the fast/declarative component leads to improvements in the slow/non-declarative component. Therefore, the fast process that supports formation of motor memory is not only neurally distinct from the slow process, but it shares critical resources with the declarative memory system. PMID:21048140

  19. Subthalamic stimulation differentially modulates declarative and nondeclarative memory.

    Science.gov (United States)

    Hälbig, Thomas D; Gruber, Doreen; Kopp, Ute A; Scherer, Peter; Schneider, Gerd-Helge; Trottenberg, Thomas; Arnold, Guy; Kupsch, Andreas

    2004-03-01

    Declarative memory has been reported to rely on the medial temporal lobe system, whereas non-declarative memory depends on basal ganglia structures. We investigated the functional role of the subthalamic nucleus (STN), a structure closely connected with the basal ganglia for both types of memory. Via deep brain high frequency stimulation (DBS) we manipulated neural activity of the STN in humans. We found that DBS-STN differentially modulated memory performance: declarative memory was impaired, whereas non-declarative memory was improved in the presence of STN-DBS indicating a specific role of the STN in the activation of memory systems. Copyright 2004 Lippincott Williams & Wilkins

  20. Excavation-drier method of energy-peat extraction reduces long-term climatic impact

    Energy Technology Data Exchange (ETDEWEB)

    Silvan, N.; Silvan, K.; Laine, J. [Finnish Forest Research Inst., Parkano (Finland)], e-mail: niko.silvan@metla.fi; Vaisanen, S.; Soukka, R. [Lappeenranta Univ.of Techology (Finland)

    2012-11-01

    Climatic impacts of energy-peat extraction are of increasing concern due to EU emissions trading requirements. A new excavation-drier peat extraction method has been developed to reduce the climatic impact and increase the efficiency of peat extraction. To quantify and compare the soil GHG fluxes of the excavation drier and the traditional milling methods, as well as the areas from which the energy peat is planned to be extracted in the future (extraction reserve area types), soil CO{sub 2}, CH{sub 4} and N{sub 2}O fluxes were measured during 2006-2007 at three sites in Finland. Within each site, fluxes were measured from drained extraction reserve areas, extraction fields and stockpiles of both methods and additionally from the biomass driers of the excavation-drier method. The Life Cycle Assessment (LCA), described at a principal level in ISO Standards 14040:2006 and 14044:2006, was used to assess the long-term (100 years) climatic impact from peatland utilisation with respect to land use and energy production chains where utilisation of coal was replaced with peat. Coal was used as a reference since in many cases peat and coal can replace each other in same power plants. According to this study, the peat extraction method used was of lesser significance than the extraction reserve area type in regards to the climatic impact. However, the excavation-drier method seems to cause a slightly reduced climatic impact as compared with the prevailing milling method. (orig.)

  1. Long term impact of emotional, social and cognitive intelligence competencies and GMAT on career and life satisfaction and career success

    OpenAIRE

    Amdurer, Emily; Boyatzis, Richard E.; Saatcioglu, Argun; Smith, Melvin L.; Taylor, Scott N.

    2014-01-01

    ABSTRACTCareer scholars have called for a broader definition of career success by inviting greater exploration of its antecedents. While success in various jobs has been predicted by intelligence and in other studies by competencies, especially in management, long term impact of having intelligence and using competencies has not been examined. Even in collegiate outcome studies, few have examined the longer term impact on graduates’ careers or lives. This study assesses the impact of demonstr...

  2. Evaluating Modeled Impact Metrics for Human Health, Agriculture Growth, and Near-Term Climate

    Science.gov (United States)

    Seltzer, K. M.; Shindell, D. T.; Faluvegi, G.; Murray, L. T.

    2017-12-01

    Simulated metrics that assess impacts on human health, agriculture growth, and near-term climate were evaluated using ground-based and satellite observations. The NASA GISS ModelE2 and GEOS-Chem models were used to simulate the near-present chemistry of the atmosphere. A suite of simulations that varied by model, meteorology, horizontal resolution, emissions inventory, and emissions year were performed, enabling an analysis of metric sensitivities to various model components. All simulations utilized consistent anthropogenic global emissions inventories (ECLIPSE V5a or CEDS), and an evaluation of simulated results were carried out for 2004-2006 and 2009-2011 over the United States and 2014-2015 over China. Results for O3- and PM2.5-based metrics featured minor differences due to the model resolutions considered here (2.0° × 2.5° and 0.5° × 0.666°) and model, meteorology, and emissions inventory each played larger roles in variances. Surface metrics related to O3 were consistently high biased, though to varying degrees, demonstrating the need to evaluate particular modeling frameworks before O3 impacts are quantified. Surface metrics related to PM2.5 were diverse, indicating that a multimodel mean with robust results are valuable tools in predicting PM2.5-related impacts. Oftentimes, the configuration that captured the change of a metric best over time differed from the configuration that captured the magnitude of the same metric best, demonstrating the challenge in skillfully simulating impacts. These results highlight the strengths and weaknesses of these models in simulating impact metrics related to air quality and near-term climate. With such information, the reliability of historical and future simulations can be better understood.

  3. Operator declarations (OPD) for Rokkasho Reprocessing Plant

    International Nuclear Information System (INIS)

    Suzuki, Masataka; Yamazaki, Yoshihiro; Hiruta, Kazuhiko; Fujimaki, Kazunori; Wuester, Jan; Gerrein, Greg; Chesnay, Bruno; ); Takeda, Seiichi; Yoshida, Hideki

    2004-01-01

    The OPD scheme is outlined with the OPD rules, data format, the structure of computer system related to OPD, how and when OPD data is submitted in this paper. Currently, the OPD overall data structure and data items for all OPD types are almost determined and agreed. But for OPD Type 31 and 32, detail checks continue as to which data should be declared based on the specific material accounting procedure for each KMP. The MACS (Material accounting computer system) has already been manufactured and installed, but the current MACS does not have the OPD generation and submission functions. OPD type, OPD class, OPD status, XML format, XML schema, OPD relevant computer systems, OPD data flow and OPD submission are explained. The target data for using OPD generation and submission functions is the start of the RRP active test. (S.Y.)

  4. DeepDive: Declarative Knowledge Base Construction.

    Science.gov (United States)

    De Sa, Christopher; Ratner, Alex; Ré, Christopher; Shin, Jaeho; Wang, Feiran; Wu, Sen; Zhang, Ce

    2016-03-01

    The dark data extraction or knowledge base construction (KBC) problem is to populate a SQL database with information from unstructured data sources including emails, webpages, and pdf reports. KBC is a long-standing problem in industry and research that encompasses problems of data extraction, cleaning, and integration. We describe DeepDive, a system that combines database and machine learning ideas to help develop KBC systems. The key idea in DeepDive is that statistical inference and machine learning are key tools to attack classical data problems in extraction, cleaning, and integration in a unified and more effective manner. DeepDive programs are declarative in that one cannot write probabilistic inference algorithms; instead, one interacts by defining features or rules about the domain. A key reason for this design choice is to enable domain experts to build their own KBC systems. We present the applications, abstractions, and techniques of DeepDive employed to accelerate construction of KBC systems.

  5. Warhead and fissile-material declarations

    International Nuclear Information System (INIS)

    von Hippel, F.

    1992-01-01

    Until recently, arms control agreements were limited by the fact that the only available verification capabilities were national technical means, which involved instruments in space or beyond national borders. As a result, the SALT II treaty constrained only the construction of large missile silos, ballistic-missile submarines and long-range bombers - and limited the flight testing of long-range ballistic missiles. Recently, however, on-site verification has been accepted, making it possible in the INF treaty to extend controls to small mobile missiles and their launchers. This paper therefore outlines a comprehensive system of verifiable limits on nuclear warheads. The authors discuss in some detail the verifiability of a halt in the production of fissile materials for nuclear warheads, the verifiability of declarations of the amounts of fissile material produced for warheads prior to the production cutoff, and the establishment of a verifiable accounting system for the numbers and types of nuclear warheads possessed by each side

  6. Long-term CO2 injection and its impact on near-surface soil microbiology.

    Science.gov (United States)

    Gwosdz, Simone; West, Julia M; Jones, David; Rakoczy, Jana; Green, Kay; Barlow, Tom; Blöthe, Marco; Smith, Karon; Steven, Michael; Krüger, Martin

    2016-12-01

    Impacts of long-term CO 2 exposure on environmental processes and microbial populations of near-surface soils are poorly understood. This near-surface long-term CO 2 injection study demonstrated that soil microbiology and geochemistry is influenced more by seasonal parameters than elevated CO 2 Soil samples were taken during a 3-year field experiment including sampling campaigns before, during and after 24 months of continuous CO 2 injection. CO 2 concentrations within CO 2 -injected plots increased up to 23% during the injection period. No CO 2 impacts on geochemistry were detected over time. In addition, CO 2 -exposed samples did not show significant changes in microbial CO 2 and CH 4 turnover rates compared to reference samples. Likewise, no significant CO 2 -induced variations were detected for the abundance of Bacteria, Archaea (16S rDNA) and gene copy numbers of the mcrA gene, Crenarchaeota and amoA gene. The majority (75%-95%) of the bacterial sequences were assigned to five phyla: Firmicutes, Proteobacteria, Actinobacteria, Acidobacteria and Bacteroidetes The majority of the archaeal sequences (85%-100%) were assigned to the thaumarchaeotal cluster I.1b (soil group). Univariate and multivariate statistical as well as principal component analyses showed no significant CO 2 -induced variation. Instead, seasonal impacts especially temperature and precipitation were detected. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Optimization of a Distillation Unit In Terms of Potential Environmental Impact and Economics

    International Nuclear Information System (INIS)

    Alhassan Salami Tijani; Ramzan, N.

    2013-01-01

    Process energy integration and continuous improvement of process technology are increasing issues to ensure profitability of chemical productions. These objectives are increasingly important due to long-term environmental impact of energy degradation, such as resource depletion, emissions and the release of waste heat. The earlier energy conservation, process economics and environmental aspects are integrated into the process development, the easier and less expensive it is to improve the process design. In this work different distillation process design alternatives have been considered with respect to evaluations of process economics and potential environmental impacts. Optimum design alternatives are analyzed related to these objectives. A multi-criteria decision making technique such as (Analytic Hierarchy Process) AHP is applied for ranking the alternatives. This method reveals that the heat pump distillation unit which has the highest score of 52 % is the best alternative when compare with base case. In terms of the effluent streams the base case has a less potential environmental impact (PEI) compared with heat pump. The lower total PEI/ kg (7.45E-01) of the base case illustrates that the material utilization efficiency of the base case is better than the heat pump whose PEI/ kg is 8.14E-01. (author)

  8. Persistent, Long-term Cerebral White Matter Changes after Sports-Related Repetitive Head Impacts

    Science.gov (United States)

    Bazarian, Jeffrey J.; Zhu, Tong; Zhong, Jianhui; Janigro, Damir; Rozen, Eric; Roberts, Andrew; Javien, Hannah; Merchant-Borna, Kian; Abar, Beau; Blackman, Eric G.

    2014-01-01

    Introduction Repetitive head impacts (RHI) sustained in contact sports are thought to be necessary for the long-term development of chronic traumatic encephalopathy (CTE). Our objectives were to: 1) characterize the magnitude and persistence of RHI-induced white matter (WM) changes; 2) determine their relationship to kinematic measures of RHI; and 3) explore their clinical relevance. Methods Prospective, observational study of 10 Division III college football players and 5 non-athlete controls during the 2011-12 season. All subjects underwent diffusion tensor imaging (DTI), physiologic, cognitive, and balance testing at pre-season (Time 1), post-season (Time 2), and after 6-months of no-contact rest (Time 3). Head impact measures were recorded using helmet-mounted accelerometers. The percentage of whole-brain WM voxels with significant changes in fractional anisotropy (FA) and mean diffusivity (MD) from Time 1 to 2, and Time 1 to 3 was determined for each subject and correlated to head impacts and clinical measures. Results Total head impacts for the season ranged from 431–1,850. No athlete suffered a clinically evident concussion. Compared to controls, athletes experienced greater changes in FA and MD from Time 1 to 2 as well as Time 1 to 3; most differences at Time 2 persisted to Time 3. Among athletes, the percentage of voxels with decreased FA from Time 1 to 2 was positively correlated with several helmet impact measures. The persistence of WM changes from Time 1 to 3 was also associated with changes in serum ApoA1 and S100B autoantibodies. WM changes were not consistently associated with cognition or balance. Conclusions A single football season of RHIs without clinically-evident concussion resulted in WM changes that correlated with multiple helmet impact measures and persisted following 6 months of no-contact rest. This lack of WM recovery could potentially contribute to cumulative WM changes with subsequent RHI exposures. PMID:24740265

  9. Declarative and Non-declarative Memory Consolidation in Children with Sleep Disorder

    OpenAIRE

    Cs?bi, Eszter; Benedek, P?lma; Janacsek, Karolina; Zavecz, Zs?fia; Katona, G?bor; Nemeth, Dezso

    2016-01-01

    Healthy sleep is essential in children’s cognitive, behavioral, and emotional development. However, remarkably little is known about the influence of sleep disorders on different memory processes in childhood. Such data could give us a deeper insight into the effect of sleep on the developing brain and memory functions and how the relationship between sleep and memory changes from childhood to adulthood. In the present study we examined the effect of sleep disorder on declarative and non-decl...

  10. Long-term impacts on sewers following food waste disposer installation in housing areas.

    Science.gov (United States)

    Mattsson, Jonathan; Hedström, Annelie; Viklander, Maria

    2014-01-01

    To increase biogas generation and decrease vehicle transportation of solid waste, the integration of food waste disposers (FWDs) into the wastewater system has been proposed. However, concerns have been raised about the long-term impact of the additional load of the FWDs on sewer systems. To examine the said impact, this study has used closed-circuit television inspection techniques to evaluate the status of 181 concrete pipes serving single family housing areas with a diameter of 225 mm, ranging from a 100% connection rate of households with an FWD to none. A minor study was also performed on a multi-family housing area, where mainly plastic pipes (200 mm) were used. The extent and distribution of deposits related to the ratio of FWDs, inclination and pipe sagging (backfalls) were ascertained by using linear regression and analysis of variance. The results showed that FWDs have had an impact on the level of deposits in the sewer, but this has, in turn, been of minor significance. With a high connection rate of FWDs upstream of a pipe, the extent of the total level of deposits, as well as finer sediments, was statistically determined to be greater. However, the majority of the deposits were observed to be small, which would suggest the impact of FWDs on sewer performance to be minor. As food waste not compatible with the FWD was seen in the sewers, educational campaigns could be beneficial to further lower the risks of sewer blocking.

  11. Long-term periodontal response to orthodontic treatment of palatally impacted maxillary canines.

    Science.gov (United States)

    Caprioglio, Alberto; Vanni, Arianna; Bolamperti, Laura

    2013-06-01

    One of the most important aspects to take into consideration when evaluating the outcome of treatment of impacted maxillary canines is the final periodontal status. The aim of the present study was to evaluate the long-term periodontal response of palatally impacted maxillary canines aligned using a codified procedure and the 'Easy Cuspid' compared with contralateral spontaneously erupted teeth. The periodontal conditions of the adjacent teeth were also considered. From an initial sample of 124 patients, 33 patients (24 females and 9 males) were selected. All patients who had undergone surgical orthodontic treatment conducted in accordance with a standardized protocol were recalled for follow-up at an average of 4.6 years after the end of treatment. The average treatment time was 29 months and the mean eruption time of the previously impacted tooth was 3.1 months. The average probing depth values showed no significant clinical differences. Probing depths recorded at the vestibular surface of the lateral incisor (P alignment of palatally impacted canines without damage to the periodontium.

  12. Long-Term Impact of a Cell Phone-Enhanced Parenting Intervention.

    Science.gov (United States)

    Lefever, Jennifer E Burke; Bigelow, Kathryn M; Carta, Judith J; Borkowski, John G; Grandfield, Elizabeth; McCune, Luke; Irvin, Dwight W; Warren, Steven F

    2017-11-01

    Home visiting programs support positive parenting in populations at-risk of child maltreatment, but their impact is often limited by poor retention and engagement. The current study assessed whether a cellular phone-supported version (PCI-C) of the Parent-Child Interactions (PCI) intervention improved long-term parenting practices, maternal depression, and children's aggression. Low-income mothers ( n = 371) of preschool-aged children were assigned to one of the three groups: PCI-C, PCI, and a wait-list control (WLC) group. Parenting improved in both intervention groups between baseline and 12-month follow-up compared to the WLC. Children in the PCI-C group were rated to be more cooperative and less aggressive than children in the WLC. The results offer evidence of the long-term effectiveness of PCI and the additional benefits of cellular phone supports for promoting intervention retention and improving children's behavior.

  13. THE IMPACT OF THE FOREIGN CAPITAL BANKS ON ENSURING FINANCIAL STABILITY ON LONG TERM

    Directory of Open Access Journals (Sweden)

    Isac\tBORS

    2015-06-01

    Full Text Available The present study is focusing on analysing the role played by the foreign banks within the national and international banking system as well the impact the foreign banks have on the autochthon banking system, on the financial activity, on the real economy and on the financial stability on long terms. The research conducted highlights the fact that along the positive impact on the banking system and on the economy of the host country, generated by their quality as vectors of mobilizing and directioning the international financial flows towards the host country, there can also be considered a negative impact. The study shows that the impact of the negative effects, that have as main cause the reversibility of the international financial flows, depends, on a great extent, on the specific conditions of the host country, on the characteristics of the foreign banks, but mostly, by the share held by the foreign countries within the framework of the host banking system. Starting from the role played by the capitalization of the banking system to ensure financial stability, the research made on Romania’s case shows both, the positive effects generated by the presence of the foreign banks and also, their vulnerability in front of this excessive dependence on the foreign capital induced by this presence. The solution to reduce this dependence can only come from the autochthon capital direction whose mobilization may countervail the gap made by the foreign banks and, by surceasing the process of financial disintermediation, to ensure the maintenance of the financial stability on long term.

  14. Long-term impacts of unconventional drilling operations on human and animal health.

    Science.gov (United States)

    Bamberger, Michelle; Oswald, Robert E

    2015-01-01

    Public health concerns related to the expansion of unconventional oil and gas drilling have sparked intense debate. In 2012, we published case reports of animals and humans affected by nearby drilling operations. Because of the potential for long-term effects of even low doses of environmental toxicants and the cumulative impact of exposures of multiple chemicals by multiple routes of exposure, a longitudinal study of these cases is necessary. Twenty-one cases from five states were followed longitudinally; the follow-up period averaged 25 months. In addition to humans, cases involved food animals, companion animals and wildlife. More than half of all exposures were related to drilling and hydraulic fracturing operations; these decreased slightly over time. More than a third of all exposures were associated with wastewater, processing and production operations; these exposures increased slightly over time. Health impacts decreased for families and animals moving from intensively drilled areas or remaining in areas where drilling activity decreased. In cases of families remaining in the same area and for which drilling activity either remained the same or increased, no change in health impacts was observed. Over the course of the study, the distribution of symptoms was unchanged for humans and companion animals, but in food animals, reproductive problems decreased and both respiratory and growth problems increased. This longitudinal case study illustrates the importance of obtaining detailed epidemiological data on the long-term health effects of multiple chemical exposures and multiple routes of exposure that are characteristic of the environmental impacts of unconventional drilling operations.

  15. Towards Improved Understanding of Drought and Drought Impacts from Long Term Earth Observation Records

    Science.gov (United States)

    Champagne, C.; Wang, S.; Liu, J.; Hadwen, T. A.

    2017-12-01

    Drought is a complex natural disaster, which often emerges slowly, but can occur at various time scales and have impacts that are not well understood. Long term observations of drought intensity and frequency are often quantified from precipitation and temperature based indices or modelled estimates of soil water storage. The maturity of satellite based observations has created the potential to enhance the understanding of drought and drought impacts, particularly in regions where traditional data sets are limited by remoteness or inaccessibility, and where drought processes are not well-quantified by models. Long term global satellite data records now provide observations of key hydrological variables, including evaporation modelled from thermal sensors, soil moisture from microwave sensors, ground water from gravity sensors and vegetation condition that can be modelled from optical sensors. This study examined trends in drought frequency, intensity and duration over diverse ecoregions in Canada, including agricultural, grassland, forested and wetland areas. Trends in drought were obtained from the Canadian Drought Monitor as well as meteorological based indices from weather stations, and evaluated against satellite derived information on evaporative stress (Anderson et al. 2011), soil moisture (Champagne et al. 2015), terrestrial water storage (Wang and Li 2016) and vegetation condition (Davidson et al. 2009). Data sets were evaluated to determine differences in how different sensors characterize the hydrology and impacts of drought events from 2003 to 2016. Preliminary results show how different hydrological observations can provide unique information that can tie causes of drought (water shortages resulting from precipitation, lack of moisture storage or evaporative stress) to impacts (vegetation condition) that hold the potential to improve the understanding and classification of drought events.

  16. Impact of Spatial and Verbal Short-Term Memory Load on Auditory Spatial Attention Gradients.

    Science.gov (United States)

    Golob, Edward J; Winston, Jenna; Mock, Jeffrey R

    2017-01-01

    Short-term memory load can impair attentional control, but prior work shows that the extent of the effect ranges from being very general to very specific. One factor for the mixed results may be reliance on point estimates of memory load effects on attention. Here we used auditory attention gradients as an analog measure to map-out the impact of short-term memory load over space. Verbal or spatial information was maintained during an auditory spatial attention task and compared to no-load. Stimuli were presented from five virtual locations in the frontal azimuth plane, and subjects focused on the midline. Reaction times progressively increased for lateral stimuli, indicating an attention gradient. Spatial load further slowed responses at lateral locations, particularly in the left hemispace, but had little effect at midline. Verbal memory load had no (Experiment 1), or a minimal (Experiment 2) influence on reaction times. Spatial and verbal load increased switch costs between memory encoding and attention tasks relative to the no load condition. The findings show that short-term memory influences the distribution of auditory attention over space; and that the specific pattern depends on the type of information in short-term memory.

  17. Impact of Spatial and Verbal Short-Term Memory Load on Auditory Spatial Attention Gradients

    Directory of Open Access Journals (Sweden)

    Edward J. Golob

    2017-11-01

    Full Text Available Short-term memory load can impair attentional control, but prior work shows that the extent of the effect ranges from being very general to very specific. One factor for the mixed results may be reliance on point estimates of memory load effects on attention. Here we used auditory attention gradients as an analog measure to map-out the impact of short-term memory load over space. Verbal or spatial information was maintained during an auditory spatial attention task and compared to no-load. Stimuli were presented from five virtual locations in the frontal azimuth plane, and subjects focused on the midline. Reaction times progressively increased for lateral stimuli, indicating an attention gradient. Spatial load further slowed responses at lateral locations, particularly in the left hemispace, but had little effect at midline. Verbal memory load had no (Experiment 1, or a minimal (Experiment 2 influence on reaction times. Spatial and verbal load increased switch costs between memory encoding and attention tasks relative to the no load condition. The findings show that short-term memory influences the distribution of auditory attention over space; and that the specific pattern depends on the type of information in short-term memory.

  18. Impact of airway obstruction on lung function in very preterm infants at term.

    Science.gov (United States)

    Hilgendorff, Anne; Reiss, Irwin; Gortner, Ludwig; Schüler, Daniel; Weber, Katrin; Lindemann, Hermann

    2008-11-01

    Morbidity and mortality in preterm infants is significantly determined by the development of pulmonary complications. We thus investigated the impact of obstructive ventilatory disorders on lung function in very preterm infants with a history of respiratory distress syndrome and/or bronchopulmonary dysplasia using repeated body plethysmographic measurements before and after bronchodilation. Lung function, including effective airway resistance (Raw), specific conductance (SGaw), functional residual capacity (FRCbox), and total respiratory system compliance (Crs, multiple occlusion technique) was assessed in 27 preterm infants pound31 wks gestational age at a median postmenstrual age of 38 wks after mild oral sedation before and after inhalation of nebulized salbutamol (1.25 mg/2.5 mL; PARI JuniorBOY N) using the MasterScreen Baby Body (Jaeger, Hoechberg, Germany). In preterm infants median Raw was initially found to be within the normal range as determined for healthy term newborns, but decreased significantly after administration of salbutamol; SGaw changed accordingly. FRCbox was significantly reduced compared with healthy term newborns (16.6 vs. 19.6 mL/kg, mean) and decreased further after bronchodilation, whereas Crs was not significantly altered. This is the first report quantifying the important impact of obstructive ventilatory disorders on lung function in very preterm infants at term. Besides its important role in preterm lung function consecutive overinflation could furthermore be shown to mask reduction of lung volume in these infants. Thus, body plethysmographic measurements seem to be an important diagnostic tool in preterm infants at term before hospital discharge in order to quantify ventilation disorders and to define therapeutic strategies.

  19. The impact of uncertainties on the UK's medium-term climate change targets

    International Nuclear Information System (INIS)

    Watson, Jim; Gross, Rob; Ketsopoulou, Ioanna; Winskel, Mark

    2015-01-01

    The UK is committed to ambitious medium- and long-term climate change targets, including a commitment to an 80% reduction in emissions from 1990 levels by 2050. Whilst emissions have fallen significantly since 1990, further reductions will be increasingly difficult to achieve. The government has agreed carbon budgets to the late 2020s that are consistent with the long-term 80% target. However, increasing energy prices since the mid-2000s and the 2008 financial crisis have led to cracks in the political consensus in support of these budgets and targets. This paper carries out an assessment of the feasibility of the UK's agreed low carbon pathway over the medium term, with a particular focus on the fourth carbon budget (2023–27). It analyses the uncertainties associated with the specific changes that may be necessary to comply with this carbon budget – including measures to decarbonise electricity, heat and transport. This analysis focuses on ‘instrumental’ uncertainties associated with specific areas of the energy system (e.g. the decarbonisation of heat in households) and ‘systemic’ uncertainties that tend to have more pervasive implications for the energy system as a whole (e.g. uncertainties associated with public attitudes). A framework is developed that sets out and analyses the key uncertainties under those two broad categories, in terms of their complexity and their potential impact on the fourth carbon budget. Through the application of this framework the paper also considers strategies to mitigate or manage these uncertainties, and which actors could help develop and implement these strategies. - Highlights: • Many uncertainties remain about the achievability of UK emissions reduction targets. • This paper assesses uncertainties that could have the greatest impact on compliance with the 4th carbon budget (2023–2027). • The paper also suggests strategies that could help to manage or mitigate these uncertainties.

  20. 19 CFR 148.111 - Written declaration for unaccompanied articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Written declaration for unaccompanied articles... of the United States § 148.111 Written declaration for unaccompanied articles. The baggage... covers articles which do not accompany him and: (a) The articles are entitled to free entry under the $1...

  1. 28 CFR 8.8 - Advertisement and declaration of forfeiture.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Advertisement and declaration of forfeiture. 8.8 Section 8.8 Judicial Administration DEPARTMENT OF JUSTICE FBI FORFEITURE AUTHORITY FOR CERTAIN STATUTES § 8.8 Advertisement and declaration of forfeiture. (a) The notice required by customs...

  2. 22 CFR 192.1 - Declarations of hostile action.

    Science.gov (United States)

    2010-04-01

    ... 192.1 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF VICTIMS OF TERRORISM COMPENSATION General § 192.1 Declarations of hostile action. (a)(1) The Secretary of State shall declare when and where individuals in the Civil Service of the United States, including members of the Foreign Service and foreign...

  3. 49 CFR 395.13 - Drivers declared out of service.

    Science.gov (United States)

    2010-10-01

    ... materials requirements prescribed in § 397.5 pertaining to attendance and surveillance of commercial motor... shall: (i) Require or permit a driver who has been declared out of service to operate a commercial motor... been declared out of service for failure to prepare a record of duty status to operate a commercial...

  4. Declaration on action for environment and health in Europe

    International Nuclear Information System (INIS)

    1994-06-01

    The Ministers of the Environment and the Ministers of Health of the European Member States of the World Health Organization (WHO) and the Members of the European Commission have met in Helsinki, Finland, and issued this declaration on Action for Environment and Health in Europe. The declaration primarily deals with environmental pollution protection, public health

  5. Universal Declaration of Human Rights: 40th Anniversary.

    Science.gov (United States)

    Adams, Juanita, Ed.

    December 10, 1988, marks the 40th anniversary of the adoption by the United Nations of the Universal Declaration of Human Rights. The Declaration represents the first comprehensive, global statement on basic human rights, embracing many of the values long held by U.S. citizens; and it urges all peoples and all nations to promote respect for the…

  6. The Universal Declaration of Human Rights - Only a Foundation.

    Science.gov (United States)

    Reichert, Elisabeth

    2002-01-01

    Explains provisions contained within the Universal Declaration of Human Rights, tracing historical beginnings of human rights to 1945, detailing events after 1945 up to the adoption of the Universal Declaration of Human Rights by the United Nations, and explaining essential terminology used in describing human rights instruments that have been…

  7. 76 FR 13655 - Agency Information Collection Activities: Ship's Store Declaration

    Science.gov (United States)

    2011-03-14

    ... Activities: Ship's Store Declaration AGENCY: U.S. Customs and Border Protection, Department of Homeland... will be submitting the following information collection request to the Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act: Ship's Stores Declaration...

  8. 78 FR 27984 - Agency Information Collection Activities: Ship's Store Declaration

    Science.gov (United States)

    2013-05-13

    ... Activities: Ship's Store Declaration AGENCY: U.S. Customs and Border Protection, Department of Homeland... will be submitting the following information collection request to the Office of Management and Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act: Ship's Stores Declaration...

  9. 76 FR 2403 - Agency Information Collection Activities: Ship's Store Declaration

    Science.gov (United States)

    2011-01-13

    ... Activities: Ship's Store Declaration AGENCY: U.S. Customs and Border Protection (CBP), Department of Homeland... requirement concerning the Ship's Stores Declaration (CBP Form 1303). This request for comment is being made... request for Office of Management and Budget (OMB) approval. All comments will become a matter of public...

  10. 78 FR 15031 - Agency Information Collection Activities: Ship's Store Declaration

    Science.gov (United States)

    2013-03-08

    ... Activities: Ship's Store Declaration AGENCY: U.S. Customs and Border Protection (CBP), Department of Homeland... requirement concerning the Ship's Stores Declaration (CBP Form 1303). This request for comment is being made... Management and Budget (OMB) approval. All comments will become a matter of public record. In this document...

  11. Sound taxation? On the use of self-declared value

    NARCIS (Netherlands)

    Haan, Marco A.; Heijnen, Pim; Schoonbeek, Lambert; Toolsema-Veldman, Linda

    In the 16th century, foreign ships passing through the Sound had to pay ad valorem taxes, known as the Sound Dues. To give skippers an incentive to declare the true value of their cargo, the Danish Crown reserved the right to purchase it at the declared value. We show that this rule does not induce

  12. Sound taxation? On the use of self-declared value

    NARCIS (Netherlands)

    Haan, M.A.; Heijnen, P.; Schoonbeek, L.; Toolsema, L.A.

    2008-01-01

    In the 16th century, foreign ships passing through the Sound had to pay ad valorem taxes, known as the Sound Dues. To give skippers an incentive to declare the true value of their cargo, the Danish Crown reserved the right to purchase it at the declared value. We show that it is an equilibrium for

  13. 76 FR 9231 - New Customs Declarations Label Requirements

    Science.gov (United States)

    2011-02-17

    ... POSTAL SERVICE 39 CFR Part 111 New Customs Declarations Label Requirements AGENCY: Postal Service... goods that enter the Customs Territory of the United States (CTUS), from outside the CTUS, to bear a customs declaration label. Additionally, the Postal Service updates the standards for items weighing 16...

  14. 47 CFR 2.906 - Declaration of Conformity.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Declaration of Conformity. 2.906 Section 2.906... Conformity. (a) A Declaration of Conformity is a procedure where the responsible party, as defined in § 2.909... of Conformity attaches to all items subsequently marketed by the responsible party which are...

  15. From Paper Based Clinical Practice Guidelines to Declarative Workflow Management

    DEFF Research Database (Denmark)

    Lyng, Karen Marie; Hildebrandt, Thomas; Mukkamala, Raghava Rao

    2009-01-01

    a sub workflow can be described in a declarative workflow management system: the Resultmaker Online Consultant (ROC). The example demonstrates that declarative primitives allow to naturally extend the paper based flowchart to an executable model without introducing a complex cyclic control flow graph....

  16. The DCR Workbench: Declarative Choreographies for Collaborative Processes

    DEFF Research Database (Denmark)

    Debois, Søren; Hildebrandt, Thomas

    2017-01-01

    analysis, time analysis, enforcement, declarative subprocesses, data dependencies, translation to other declarative models, and more. This chapter introduces the Workbench and, through the features of the Workbench, surveys the DCR formalism. The Workbench is available on-line at http: //dcr.tools....

  17. Review of declarations received by the AFSSAPS and the ASN on the account of radio-vigilance (external radiotherapy). July 2007 - June 2008

    International Nuclear Information System (INIS)

    2009-09-01

    After a presentation of the procedure of declaration of significant radiation protection events, of the ASN-SFRO event scale, and of the indication procedure related to material vigilance, this report proposes a review and an analysis of significant radioprotection and material vigilance events which have been declared between July 2007 and June 2008. The assessment of radiation protection events declared to the ASN is as well quantitative (distribution in time, geographical distribution, status of declaring centres, declaration delays, classification according to the ASN-SFRO scale) as qualitative (origin, event typology, stage of the treatment process at which the event occurred and has been detected, personnel having detected the event, communication about events). The analysis of material vigilance events addresses the evolution of their number, their distribution in terms of declarer type, of radiotherapy equipment, or of criticality level, and so on. A review of hybrid accidents is proposed (concerned equipment, declarer origin, consequences of the declarations, classification on the ASN-SFRO scale)

  18. Long-term Health and Socioeconomic Impacts of Landscape Fire Emissions in Indonesia

    Science.gov (United States)

    Jina, A.; Marlier, M. E.

    2013-12-01

    Among natural disasters, wildfires are perhaps the most complex case of a coupled human-natural system, with both direct and indirect costs to society. A major contributor to these indirect costs is the impact upon health in the short- and long-term. Air pollution from fires is associated with more deaths from cardio-pulmonary diseases, yet little or no research has looked beyond the short-term mortality and morbidity associated with wildfire pollution, particularly in developing countries where impacts may be greatest but monitoring presents a constant challenge. We address this by using an interdisciplinary approach combining modeled air pollution with econometric methods to identify the long-term effects of air pollution on health and cognitive ability. These impacts will persist in society, and can lead to decreased education, loss of earnings, and a suppression of economic activity. We take the case of Indonesia, which is prone to large, catastrophic fires during El Niño conditions. Satellite data partially compensate for the lack of monitoring data for air pollution, but there are still significant gaps in data availability and difficulty in retrieving surface concentrations. In this study, surface fine particulate matter (PM2.5) concentrations at 2x2.5° resolution are obtained from GISS-E2-Puccini (the new version of the NASA GISS ModelE General Circulation Model (GCM)), run with monthly fire emissions from the Global Fire Emissions Database version 3 (GFED3). 24-hour ambient PM2.5 concentrations across Indonesia are matched to geographically and socioeconomic surveys. We find that exposure to high levels of PM2.5 at birth (and in utero) has negative impacts upon physical development of infants. This is associated with health problems later in life, as well as lower educational and labor market outcomes. A one standard deviation increase in ambient air pollution exposure leads to effects comparable to those from indoor air pollution. We also find a

  19. 75 FR 16810 - Determination and Declarations Regarding Emergency Use of Certain In vitro Diagnostic, Antiviral...

    Science.gov (United States)

    2010-04-02

    ... specified that these declarations are declarations of emergency as defined by former Secretary Michael O... essence in detecting, preventing, and treating illness and death by getting in vitro diagnostic, antiviral... that the declaration is a declaration of emergency, as defined in the December 17, 2008 Declaration...

  20. SECURITY IN SUSTAINABLE DEVELOPMENT: COMPARING UNITED NATIONS 2030 AGENDA FOR SUSTAINABLE DEVELOPMENT WITH MILLENNIUM DECLARATION

    Directory of Open Access Journals (Sweden)

    Ahmet BARBAK

    2017-06-01

    Full Text Available This study aims to compare United Nations 2030 Agenda for Sustainable Development with Millennium Declaration in terms of their security conceptualizations to explore changes in security thinking and policy components (goals, targets, principles, priorities etc. over time. In doing so, it is envisaged that United Nations’ expectations from member states regarding their national security policies and organizations could be revealed. Security thinking has changed since late 1980’s with the introduction of sustainable development approach by the United Nations. This shift in security thinking encompasses human security and security-development nexus. Holding all member states responsible, Millennium Declaration and 2030 Agenda for Sustainable Development constitute the primary and the most recent outcome documents of United Nations’ sustainable development policy. Both documents have security components. This enables extracting security elements and comparing them with an analytical manner. Consequently, findings are compared and discussed in terms of public policy and organization at national level.

  1. The community impact of consolidating long-term inpatient care at a single state hospital.

    Science.gov (United States)

    Wolff, N

    2000-06-01

    A community impact model was used to estimate how consolidation of all long-term inpatient care at one state mental hospital affected the town in which the hospital was located. Qualitative and quantitative methods were used to measure objective and subjective impacts of the hospital's expanded role. Objective impacts included employment, retail sales, and use of local services such as police, welfare, and education. Subjective impacts included residents' perceptions of safety. Data were obtained from hospital records, service providers, merchants, residents, and persons living on the streets or in shelters. Overall, the policy had a positive net impact on the community, estimated at roughly $4 million during the 18 months after implementation. Nearly $1 million was a direct payment from the state in lieu of taxes for the property occupied by the hospital. The hospital's payments to businesses in the town increased 10 percent. The number of hospital employees increased by 61 percent, to 1,336. The number of local residents working in the hospital grew from 200 to 320, and the proportion of the hospital's annual payroll paid to local residents increased from 14 to 24 percent. Local service use did not increase, and no change was noted in the crime rate. More patients were discharged to other towns than were admitted from the host town. Eighty percent of the residents surveyed said the town had either improved or had not changed. The benefits brought by the consolidation are likely to be sustained in the long run if the state continues the current rate of payments to the community and the hospital continues its policy of discharging patients to the town where they resided before hospitalization.

  2. Glucose variability negatively impacts long-term functional outcome in patients with traumatic brain injury.

    Science.gov (United States)

    Matsushima, Kazuhide; Peng, Monica; Velasco, Carlos; Schaefer, Eric; Diaz-Arrastia, Ramon; Frankel, Heidi

    2012-04-01

    Significant glycemic excursions (so-called glucose variability) affect the outcome of generic critically ill patients but has not been well studied in patients with traumatic brain injury (TBI). The purpose of this study was to evaluate the impact of glucose variability on long-term functional outcome of patients with TBI. A noncomputerized tight glucose control protocol was used in our intensivist model surgical intensive care unit. The relationship between the glucose variability and long-term (a median of 6 months after injury) functional outcome defined by extended Glasgow Outcome Scale (GOSE) was analyzed using ordinal logistic regression models. Glucose variability was defined by SD and percentage of excursion (POE) from the preset range glucose level. A total of 109 patients with TBI under tight glucose control had long-term GOSE evaluated. In univariable analysis, there was a significant association between lower GOSE score and higher mean glucose, higher SD, POE more than 60, POE 80 to 150, and single episode of glucose less than 60 mg/dL but not POE 80 to 110. After adjusting for possible confounding variables in multivariable ordinal logistic regression models, higher SD, POE more than 60, POE 80 to 150, and single episode of glucose less than 60 mg/dL were significantly associated with lower GOSE score. Glucose variability was significantly associated with poorer long-term functional outcome in patients with TBI as measured by the GOSE score. Well-designed protocols to minimize glucose variability may be key in improving long-term functional outcome. Copyright © 2012 Elsevier Inc. All rights reserved.

  3. Long-term impact of perfusion CT data after subarachnoid hemorrhage

    Energy Technology Data Exchange (ETDEWEB)

    Mathys, Christian; Martens, Daniel; Reichelt, Dorothea C.; Caspers, Julian; Aissa, Joel; May, Rebecca; Antoch, Gerald; Turowski, Bernd [University Duesseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Duesseldorf (Germany); Haenggi, Daniel [University Duesseldorf, Medical Faculty, Department of Neurosurgery, Duesseldorf (Germany)

    2013-11-15

    Dynamic perfusion computed tomography (PCT) has been established as a diagnostic instrument for the detection of vasospasm after subarachnoid hemorrhage (SAH). The purpose of this study was to assess the prognostic impact of PCT parameters after SAH on the long-term outcome of patients. Three hundred twelve patients were retrospectively interrogated with a questionnaire 23.06 {+-} 14.33 months after spontaneous subarachnoid hemorrhage. The modified Rankin scale (mRS) was determined, respectively. Scheduled PCT data sets from the first days after ictus were available for all patients. The maximum mean transit time over several examinations per hemisphere (MTT{sub PEAK}) values were significantly correlated (p {<=} 0.001, r = 0.422) with the clinical long-term outcome (mRS). Corresponding to our linear regression analysis, MTT{sub PEAK} is the second most important regressor (behind clinical severity of the initial hemorrhage) for the prediction of long-term mRS. An MTT{sub PEAK} threshold of 3.98 s (identified by receiver operating characteristic analysis, area under the curve = 0.75) predicted an unfavorable long-term outcome (mRS {>=} 2) with a sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of 67.3, 74.3, 84.5, 52.1, and 69.6 %, respectively. The presented data corroborate the relevance of PCT data for the clinical long-term outcome of SAH patients. By identification of patients who are at risk for a bad outcome and may need escalation of therapy, risk-benefit analysis is supported. (orig.)

  4. Impact of Short-term Changes In Earthquake Hazard on Risk In Christchurch, New Zealand

    Science.gov (United States)

    Nyst, M.

    2012-12-01

    The recent Mw 7.1, 4 September 2010 Darfield, and Mw 6.2, 22 February 2011 Christchurch, New Zealand earthquakes and the following aftershock activity completely changed the existing view on earthquake hazard of the Christchurch area. Not only have several faults been added to the New Zealand fault database, the main shocks were also followed by significant increases in seismicity due to high aftershock activity throughout the Christchurch region that is still on-going. Probabilistic seismic hazard assessment (PSHA) models take into account a stochastic event set, the full range of possible events that can cause damage or loss at a particular location. This allows insurance companies to look at their risk profiles via average annual losses (AAL) and loss-exceedance curves. The loss-exceedance curve is derived from the full suite of seismic events that could impact the insured exposure and plots the probability of exceeding a particular loss level over a certain period. Insurers manage their risk by focusing on a certain return period exceedance benchmark, typically between the 100 and 250 year return period loss level, and then reserve the amount of money needed to account for that return period loss level, their so called capacity. This component of risk management is not too sensitive to short-term changes in risk due to aftershock seismicity, as it is mostly dominated by longer-return period, larger magnitude, more damaging events. However, because the secondairy uncertainties are taken into account when calculating the exceedance probability, even the longer return period losses can still experience significant impact from the inclusion of time-dependent earthquake behavior. AAL is calculated by summing the product of the expected loss level and the annual rate for all events in the event set that cause damage or loss at a particular location. This relatively simple metric is an important factor in setting the annual premiums. By annualizing the expected losses

  5. Impact of diabetes on treatment outcomes and long-term survival in multidrug-resistant tuberculosis.

    Science.gov (United States)

    Kang, Young Ae; Kim, Song Yee; Jo, Kyung-Wook; Kim, Hee Jin; Park, Seung-Kyu; Kim, Tae-Hyung; Kim, Eun Kyung; Lee, Ki Man; Lee, Sung Soon; Park, Jae Seuk; Koh, Won-Jung; Kim, Dae Yun; Shim, Tae Sun

    2013-01-01

    Few studies have investigated the impact of diabetes mellitus (DM), a globally increasing metabolic disease, on treatment outcomes and long-term survival in patients with multidrug-resistant forms of tuberculosis (MDR-TB). We analyzed outcomes in a large cohort to assess the impact of DM on treatment outcomes of patients with MDR-TB. MDR-TB patients newly diagnosed or retreated between 2000 and 2002 and followed for 8-11 years were retrospectively analyzed with respect to the effect of DM as a comorbidity on their treatment outcome and long-term survival. Of 1,407 patients with MDR-TB, 239 (17.0%) had coexisting DM. The mean age and body mass index were higher in MDR-TB patients with DM [MDR-TBDM(+)] than in those without DM [MDR-TBDM(-)]. Patients with MDR-TB and a comorbidity of DM had a significantly lower treatment success rate than those without a history of DM (36.0 vs. 47.2%, p = 0.002). In addition, DM was the negative predictor for MDR-TB treatment success in multivariate analyses [odds ratio 0.51, 95% confidence interval (CI) 0.26-0.99]. Mean survival times were also lower in MDR-TBDM(+) than in MDR-TBDM(-) patients (102 vs. 114 months, p = 0.001), with DM as a significant predictor of poor long-term survival in multivariate analyses (hazard ratio 1.59, 95% CI 1.01-2.50). Among MDR-TB patients, DM was a relatively common comorbidity. In patients undergoing treatment for MDR-TB and followed for 8-11 years, it was found to be independently associated with an increased risk of both treatment failure and death. Copyright © 2013 S. Karger AG, Basel.

  6. Nonhuman Primates do Declare! A Comparison of Declarative Symbol and Gesture Use in Two Children, Two Bonobos, and A Chimpanzee

    Science.gov (United States)

    Lyn, Heidi; Greenfield, Patricia M.; Savage-Rumbaugh, Sue; Gillespie-Lynch, Kristen; Hopkins, William D.

    2011-01-01

    While numerous publications have shown that apes can learn some aspects of human language, one frequently cited difference between humans and apes is the relative infrequency of declaratives (comments and statements) as opposed to imperatives (requests) in ape symbol use. This paper describes the use of declaratives in three language-competent apes and two children. The apes produced a lower proportion of spontaneous declaratives than did the children. However, both groups used declaratives to name objects, to interact and negotiate, and to make comments about other individuals. Both apes and children also made comments about past and future events. However, showing/offering/giving, attention getting, and comments on possession were declarative types made by the children but rarely by the apes. PMID:21516208

  7. The Impact of Long-Term Climate Change on Nitrogen Runoff at the Watershed Scale.

    Science.gov (United States)

    Dorley, J.; Duffy, C.; Arenas Amado, A.

    2017-12-01

    The impact of agricultural runoff is a major concern for water quality of mid-western streams. This concern is largely due to excessive use of agricultural fertilizer, a major source of nutrients in many Midwestern watersheds. In order to improve water quality in these watersheds, understanding the long-term trends in nutrient concentration and discharge is an important water quality problem. This study attempts to analyze the role of long-term temperature and precipitation on nitrate runoff in an agriculturally dominated watershed in Iowa. The approach attempts to establish the concentration-discharge (C-Q) signature for the watershed using time series analysis, frequency analysis and model simulation. The climate data is from the Intergovernmental Panel on Climate Change (IPCC), model GFDL-CM3 (Geophysical Fluid Dynamic Laboratory Coupled Model 3). The historical water quality data was made available by the IIHR-Hydroscience & Engineering at the University of Iowa for the clear creek watershed (CCW). The CCW is located in east-central Iowa. The CCW is representative of many Midwestern watersheds with humid-continental climate with predominantly agricultural land use. The study shows how long-term climate changes in temperature and precipitation affects the C-Q dynamics and how a relatively simple approach to data analysis and model projections can be applied to best management practices at the site.

  8. Short- and long-term impact of critical illness on relatives: literature review.

    Science.gov (United States)

    Paul, Fiona; Rattray, Janice

    2008-05-01

    This paper is a report of a literature review undertaken to identify the short- and long-term impact of critical illness on relatives. Patients in intensive care can experience physical and psychological consequences, and their relatives may also experience such effects. Although it is recognized that relatives have specific needs, it is not clear whether these needs are always met and whether further support is required, particularly after intensive care. The following databases were searched for the period 1950-2007: Medline, British Nursing Index and Archive, EMBASE, CINAHL, PsycINFO and EMB Reviews--Cochrane Central Register of Clinical Trials. Search terms focused on adult relatives of critically ill adult patients during and after intensive care. Recurrent topics were categorized to structure the review, i.e. 'relatives needs', 'meeting relatives' needs', 'interventions', 'satisfaction', 'psychological outcomes' and 'coping'. Studies have mainly identified relatives' immediate needs using the Critical Care Family Needs Inventory. There are few studies of interventions to meet relatives' needs and the short- and long-term effects of critical illness on relatives. Despite widespread use of the Critical Care Family Needs Inventory, factors such as local or cultural differences may influence relatives' needs. Relatives may also have unidentified needs, and these needs should be explored. Limited research has been carried out into interventions to meet relatives' needs and the effects of critical illness on their well-being, yet some relatives may experience negative psychological consequences far beyond the acute phase of the illness.

  9. Postoperative CPAP use impacts long-term weight loss following bariatric surgery.

    Science.gov (United States)

    Collen, Jacob; Lettieri, Christopher J; Eliasson, Arn

    2015-03-15

    Obstructive sleep apnea (OSA) is common among bariatric surgery candidates. After surgical weight loss, OSA frequently persists and untreated OSA can lead to weight gain. Long-term continuous positive airway pressure (CPAP) adherence is unclear and poor adherence may worsen weight loss outcomes. We sought to determine the impact of CPAP use on long-term weight-loss outcomes in a cohort of bariatric patients. Long-term observational study of bariatric surgery patients with OSA. Patients were evaluated with polysomnography preoperatively and one-year postoperatively. The cohort was again evaluated a mean of 7.2 years later to determine the relationship between long-term CPAP use and subsequent regain of weight. Twenty-four consecutive patients (aged 48.5 ± 9.4 years at time of surgery; 73% female) were included in the initial assessment, and long-term outcome data were available on 22 subjects. Persistent OSA was documented in 21 of 22 subjects (95%) one year postoperatively. Final evaluation occurred 7.2 ± 2.3 years following surgery. Weight (213.3 ± 39.1 to 235.3 ± 47.1 lb, p = 0.10) and BMI (32.5 ± 5.4 to 37.3 ± 8.2 kg/m(2), p = 0.03) increased in most (n = 19, 86.4%) from postoperative to final evaluation. CPAP use declined from 83.3% (preoperatively) to 38.1% (one year) and to 23.8% (final evaluation). BMI increased among those not using CPAP at long-term follow-up compared to those with continued CPAP use (6.8% v -1.8%, p = 0.05). In our cohort of bariatric patients with OSA, long-term adherence to CPAP therapy was poor, and non-adherence was associated with weight gain. Ongoing follow-up of OSA in this population may help to preserve initial achievements after surgical weight loss. © 2014 American Academy of Sleep Medicine.

  10. Declarative Terrain Modeling for Military Training Games

    Directory of Open Access Journals (Sweden)

    Ruben M. Smelik

    2010-01-01

    Full Text Available Military training instructors increasingly often employ computer games to train soldiers in all sorts of skills and tactics. One of the difficulties instructors face when using games as a training tool is the creation of suitable content, including scenarios, entities, and corresponding terrain models. Terrain plays a key role in many military training games, as for example, in our case game Tactical Air Defense. However, current manual terrain editors are both too complex and too time-consuming to be useful for instructors; automatic terrain generation methods show a lot of potential, but still lack user control and intuitive editing capabilities. We present a novel way for instructors to model terrain for their training games: instead of constructing a terrain model using complex modeling tools, instructors can declare the required properties of their terrain using an advanced sketching interface. Our framework integrates terrain generation methods and manages dependencies between terrain features in order to automatically create a complete 3D terrain model that matches the sketch. With our framework, instructors can easily design a large variety of terrain models that meet their training requirements.

  11. A shared resource between declarative memory and motor memory.

    Science.gov (United States)

    Keisler, Aysha; Shadmehr, Reza

    2010-11-03

    The neural systems that support motor adaptation in humans are thought to be distinct from those that support the declarative system. Yet, during motor adaptation changes in motor commands are supported by a fast adaptive process that has important properties (rapid learning, fast decay) that are usually associated with the declarative system. The fast process can be contrasted to a slow adaptive process that also supports motor memory, but learns gradually and shows resistance to forgetting. Here we show that after people stop performing a motor task, the fast motor memory can be disrupted by a task that engages declarative memory, but the slow motor memory is immune from this interference. Furthermore, we find that the fast/declarative component plays a major role in the consolidation of the slow motor memory. Because of the competitive nature of declarative and nondeclarative memory during consolidation, impairment of the fast/declarative component leads to improvements in the slow/nondeclarative component. Therefore, the fast process that supports formation of motor memory is not only neurally distinct from the slow process, but it shares critical resources with the declarative memory system.

  12. 75 FR 60133 - Agency Information Collection Activities: Declaration of Ultimate Consignee That Articles Were...

    Science.gov (United States)

    2010-09-29

    ... Activities: Declaration of Ultimate Consignee That Articles Were Exported for Temporary Scientific or... the Declaration of Ultimate Consignee That Articles Were Exported for Temporary Scientific or...: Title: Declaration of Ultimate Consignee That Articles Were Exported for Temporary Scientific or...

  13. Impact of Prosthesis-Patient Mismatch on Long-term Functional Capacity After Mechanical Aortic Valve Replacement

    NARCIS (Netherlands)

    Petit-Eisenmann, H.; Epailly, E.; Velten, M.; Radojevic, J.; Eisenmann, B.; Kremer, H.; Kindo, M.

    2016-01-01

    BACKGROUND: The impact of prosthesis-patient mismatch (PPM) after aortic valve replacement (AVR) for aortic stenosis on exercise capacity remains controversial. The aim of this study was to analyze the long-term impact of PPM after mechanical AVR on maximal oxygen uptake (VO2max). METHODS: The study

  14. Ecological impacts of long-term application of biosolids to a radiata pine plantation

    International Nuclear Information System (INIS)

    Xue, Jianming; Kimberley, Mark O.; Ross, Craig; Gielen, Gerty; Tremblay, Louis A.; Champeau, Olivier; Horswell, Jacqui; Wang, Hailong

    2015-01-01

    Assessment of the ecological impact of applying biosolids is important for determining both the risks and benefits. This study investigated the impact on soil physical, chemical and biological properties, tree nutrition and growth of long-term biosolids applications to a radiata pine (Pinus radiata D. Don) plantation growing on a Sandy Raw Soil in New Zealand. Biosolids were applied to the trial site every 3 years from tree age 6 to 19 years at three application rates: 0 (Control), 300 (Standard) and 600 (High) kg nitrogen (N) ha −1 , equivalent to 0, 3 and 6 Mg ha −1 of dry biosolids, respectively. Tree nutrition status and growth have been monitored annually. Soil samples were collected 13 years after the first biosolids application to assess the soil properties and functioning. Both the Standard and High biosolids treatments significantly increased soil (0–50 cm depth) total carbon (C), N, and phosphorus (P), Olsen P and cation exchange capacity (CEC), reduced soil pH, but had no significant effects on soil (0–20 cm depth) physical properties including bulk density, total porosity and unsaturated hydraulic conductivity. The High biosolids treatment also increased concentrations of soil total cadmium (Cd), chromium (Cr), copper (Cu) and lead (Pb) at 25–50 cm depth, but these concentrations were still considered very low for a soil. Ecotoxicological assessment showed no significant adverse effects of biosolids application on either the reproduction of springtails (Folsomia candida) or substrate utilisation ability of the soil microbial community, indicating no negative ecological impact of bisolids-derived heavy metals or triclosan. This study demonstrated that repeated application of biosolids to a plantation forest on a poor sandy soil could significantly improve soil fertility, tree nutrition and pine productivity. However, the long-term fate of biosolids-derived N, P and litter-retained heavy metals needs to be further monitored in the receiving

  15. Ecological impacts of long-term application of biosolids to a radiata pine plantation

    Energy Technology Data Exchange (ETDEWEB)

    Xue, Jianming, E-mail: jianming.xue@scionresearch.com [Scion, Private Bag 29237, Christchurch (New Zealand); Kimberley, Mark O., E-mail: mark.kimberley@scionresearch.com [Scion, Private Bag 3020, Rotorua (New Zealand); Ross, Craig, E-mail: rossc@landcareresearch.co.nz [Landcare, Private Bag 11052, Palmerston North (New Zealand); Gielen, Gerty, E-mail: gerty.gielen@scionresearch.com [Scion, Private Bag 3020, Rotorua (New Zealand); Tremblay, Louis A., E-mail: louis.tremblay@cawthron.org.nz [Cawthron Institute, Private Bag 2, Nelson (New Zealand); School of Biological Sciences, University of Auckland, PO Box 92019, Auckland 1142 (New Zealand); Champeau, Olivier, E-mail: olivier.champeau@cawthron.org.nz [Cawthron Institute, Private Bag 2, Nelson (New Zealand); Horswell, Jacqui, E-mail: jacqui.horswell@esr.cri.nz [ESR, P O Box 50-348, Porirua (New Zealand); Wang, Hailong, E-mail: hailong@zafu.edu.cn [Scion, Private Bag 3020, Rotorua (New Zealand); Key Laboratory of Soil Contamination Bioremediation of Zhejiang Province, Zhejiang Agricultural and Forestry University, Lin' an, Hangzhou, Zhejiang Province 311300 (China)

    2015-10-15

    Assessment of the ecological impact of applying biosolids is important for determining both the risks and benefits. This study investigated the impact on soil physical, chemical and biological properties, tree nutrition and growth of long-term biosolids applications to a radiata pine (Pinus radiata D. Don) plantation growing on a Sandy Raw Soil in New Zealand. Biosolids were applied to the trial site every 3 years from tree age 6 to 19 years at three application rates: 0 (Control), 300 (Standard) and 600 (High) kg nitrogen (N) ha{sup −1}, equivalent to 0, 3 and 6 Mg ha{sup −1} of dry biosolids, respectively. Tree nutrition status and growth have been monitored annually. Soil samples were collected 13 years after the first biosolids application to assess the soil properties and functioning. Both the Standard and High biosolids treatments significantly increased soil (0–50 cm depth) total carbon (C), N, and phosphorus (P), Olsen P and cation exchange capacity (CEC), reduced soil pH, but had no significant effects on soil (0–20 cm depth) physical properties including bulk density, total porosity and unsaturated hydraulic conductivity. The High biosolids treatment also increased concentrations of soil total cadmium (Cd), chromium (Cr), copper (Cu) and lead (Pb) at 25–50 cm depth, but these concentrations were still considered very low for a soil. Ecotoxicological assessment showed no significant adverse effects of biosolids application on either the reproduction of springtails (Folsomia candida) or substrate utilisation ability of the soil microbial community, indicating no negative ecological impact of bisolids-derived heavy metals or triclosan. This study demonstrated that repeated application of biosolids to a plantation forest on a poor sandy soil could significantly improve soil fertility, tree nutrition and pine productivity. However, the long-term fate of biosolids-derived N, P and litter-retained heavy metals needs to be further monitored in the

  16. Long-term Impact of Bile Duct Injury on Morbidity, Mortality, Quality of Life, and Work Related Limitations

    NARCIS (Netherlands)

    Booij, Klaske A. C.; de Reuver, Philip R.; van Dieren, Susan; van Delden, Otto M.; Rauws, Erik A.; Busch, Olivier R.; van Gulik, Thomas M.; Gouma, Dirk J.

    2017-01-01

    Assessment of long-term comprehensive outcome of multimodality treatment of bile duct injury (BDI) in terms of morbidity, mortality, quality of life (QoL), survival, and work related limitations. The impact of BDI on work ability is scarcely investigated. BDI patients referred to a tertiary center

  17. Energy storage systems impact on the short-term frequency stability of distributed autonomous microgrids, an analysis using aggregate models

    DEFF Research Database (Denmark)

    Serban, Ioan; Teodorescu, Remus; Marinescu, Corneliu

    2013-01-01

    This study analyses the integration impact of battery energy storage systems (BESSs) on the short-term frequency control in autonomous microgrids (MGs). Short-term frequency stability relates with the primary or speed control level, as defined in the regulations of the classical grids. The focus...

  18. Exformatics Declarative Case Management Workflows as DCR Graphs

    DEFF Research Database (Denmark)

    Slaats, Tijs; Mukkamala, Raghava Rao; Hildebrandt, Thomas

    2013-01-01

    Declarative workflow languages have been a growing research subject over the past ten years, but applications of the declarative approach in industry are still uncommon. Over the past two years Exformatics A/S, a Danish provider of Electronic Case Management systems, has been cooperating...... with researchers at IT University of Copenhagen (ITU) to create tools for the declarative workflow language Dynamic Condition Response Graphs (DCR Graphs) and incorporate them into their products and in teaching at ITU. In this paper we give a status report over the work. We start with an informal introduction...

  19. Impact of microbial activity on the radioactive waste disposal: long term prediction of biocorrosion processes.

    Science.gov (United States)

    Libert, Marie; Schütz, Marta Kerber; Esnault, Loïc; Féron, Damien; Bildstein, Olivier

    2014-06-01

    This study emphasizes different experimental approaches and provides perspectives to apprehend biocorrosion phenomena in the specific disposal environment by investigating microbial activity with regard to the modification of corrosion rate, which in turn can have an impact on the safety of radioactive waste geological disposal. It is found that iron-reducing bacteria are able to use corrosion products such as iron oxides and "dihydrogen" as new energy sources, especially in the disposal environment which contains low amounts of organic matter. Moreover, in the case of sulphate-reducing bacteria, the results show that mixed aerobic and anaerobic conditions are the most hazardous for stainless steel materials, a situation which is likely to occur in the early stage of a geological disposal. Finally, an integrated methodological approach is applied to validate the understanding of the complex processes and to design experiments aiming at the acquisition of kinetic data used in long term predictive modelling of biocorrosion processes. © 2013.

  20. The impact of aging and hearing status on verbal short-term memory.

    Science.gov (United States)

    Verhaegen, Clémence; Collette, Fabienne; Majerus, Steve

    2014-01-01

    The aim of this study is to assess the impact of hearing status on age-related decrease in verbal short-term memory (STM) performance. This was done by administering a battery of verbal STM tasks to elderly and young adult participants matched for hearing thresholds, as well as to young normal-hearing control participants. The matching procedure allowed us to assess the importance of hearing loss as an explanatory factor of age-related STM decline. We observed that elderly participants and hearing-matched young participants showed equal levels of performance in all verbal STM tasks, and performed overall lower than the normal-hearing young control participants. This study provides evidence for recent theoretical accounts considering reduced hearing level as an important explanatory factor of poor auditory-verbal STM performance in older adults.

  1. Short-term impact of blue mussel dredging ( Mytilus edulis L.) on a benthic community

    DEFF Research Database (Denmark)

    Dolmer, Per; Kristensen, T.; Christiansen, M.L.

    2001-01-01

    The short-term effect of mussel dredging in a brackish Danish sound was studied. A commercial dredging track was identified and an analysis of the species composition inside the track and at an adjacent control area showed that dredging changed the community structure by reducing the density...... of polychaetes. In order to investigate the extent and the duration of the dredging impact experimental dredging was conducted. The experimental dredging removed 50% of the mussels in two dredged areas. Immediately after dredging, a significantly lower number of species was measured inside the mussel beds...... in dredged areas compared to control and boundary areas. This effect lasted for at least 40 days. The analysis of the species composition showed that the dredged area had a significantly lower density, particularly of polychaetes compared to the boundary area. An increased number of species was recorded...

  2. The Impact of the 2008 Crisis on BM&FBovespa’s Term Structure of Conditional Correlations

    Directory of Open Access Journals (Sweden)

    Mauro Mastella

    2014-05-01

    Full Text Available This article uses a BEKK-MGARCH model to identify the historical behavior of the term structure of covariance of the Brazilian BM&FBovespa stock exchange when compared to other exchanges in the American continent. The purpose of this research is to analyze the impact of the 2008 crisis on the cohesion of the Brazilian stock exchange when compared to the other exchanges in the sample. To this end, historical series were collected from five different stock market indexes ranging from the pre-crisis period until 2011. The bivariate modeling results indicate the presence of increased cohesion in the stock market indexes during the crisis period and the non-return of this cohesion to pre-crisis levels. They also indicate that, among the pairs analyzed, the pair of indexes IBOV x IPSA are the most appropriate choice for portfolio diversification.

  3. Impact of obesity on long-term survival after aortic valve replacement with a small prosthesis.

    Science.gov (United States)

    Wang, Biao; Yang, Hongyang; Wang, Tao; Zhang, Xiquan; Zhu, Wenjie; Cao, Guangqing; Wu, Shuming

    2013-07-01

    Although many studies have evaluated the impact of obesity on various medical treatments, it is not known whether obesity is related to late mortality with implantation of small aortic prostheses. This study evaluated the effect of obesity on the late survival of patients after aortic valve replacement (AVR) with implantation of a small aortic prosthesis (size ≤ 21 mm). From January 1998 to December 2008, 307 patients in our institution who underwent primary AVR with smaller prostheses survived 30 days after surgery. Patients were categorized as normal weight if body mass index (BMI) was prosthesis. Obesity or/and overweight may also affect the NYHA classification, even in the longer term. EOAI should be improved where possible, as it may reduce late mortality and improve quality of life in obese or overweight patients.

  4. Declarative verbal memory impairments in middle-aged women who are caregivers of offspring with autism spectrum disorders: The role of negative affect and testosterone.

    Science.gov (United States)

    Romero-Martínez, A; González-Bono, E; Salvador, A; Moya-Albiol, L

    2016-01-01

    Caring for offspring diagnosed with a chronic psychological disorder such as autism spectrum disorder (ASD) is used in research as a model of chronic stress. This chronic stress has been reported to have deleterious effects on caregivers' cognition, particularly in verbal declarative memory. Moreover, such cognitive decline may be mediated by testosterone (T) levels and negative affect, understood as depressive mood together with high anxiety and anger. This study aimed to compare declarative memory function in middle-aged women who were caregivers for individuals with ASD (n = 24; mean age = 45) and female controls (n = 22; mean age = 45), using a standardised memory test (Rey's Auditory Verbal Learning Test). It also sought to examine the role of care recipient characteristics, negative mood and T levels in memory impairments. ASD caregivers were highly sensitive to proactive interference and verbal forgetting. In addition, they had higher negative affect and T levels, both of which have been associated with poorer verbal memory performance. Moreover, the number of years of caregiving affected memory performance and negative affect, especially, in terms of anger feelings. On the other hand, T levels in caregivers had a curvilinear relationship with verbal memory performance; that is, increases in T were associated with improvements in verbal memory performance up to a certain point, but subsequently, memory performance decreased with increasing T. Chronic stress may produce disturbances in mood and hormonal levels, which in turn might increase the likelihood of developing declarative memory impairments although caregivers do not show a generalised decline in memory. These findings should be taken into account for understanding the impact of cognitive impairments on the ability to provide optimal caregiving.

  5. Abiotic dechlorination in rock matrices impacted by long-term exposure to TCE.

    Science.gov (United States)

    Schaefer, Charles E; Towne, Rachael M; Lippincott, David R; Lacombe, Pierre J; Bishop, Michael E; Dong, Hailiang

    2015-01-01

    Field and laboratory tests were performed to evaluate the abiotic reaction of trichloroethene (TCE) in sedimentary rock matrices. Hydraulically conductive fractures, and the rock directly adjacent to the hydraulically conductive fractures, within a historically contaminated TCE bedrock aquifer were used as the basis for this study. These results were compared to previous work using rock that had not been exposed to TCE (Schaefer et al., 2013) to assess the impact of long-term TCE exposure on the abiotic dechlorination reaction, as the longevity of these reactions after long-term exposure to TCE was hitherto unknown. Results showed that potential abiotic TCE degradation products, including ethane, ethene, and acetylene, were present in the conductive fractures. Using minimally disturbed slices of rock core at and near the fracture faces, laboratory testing on the rocks confirmed that abiotic dechlorination reactions between the rock matrix and TCE were occurring. Abiotic daughter products measured in the laboratory under controlled conditions were consistent with those measured in the conductive fractures, except that propane also was observed as a daughter product. TCE degradation measured in the laboratory was well described by a first order rate constant through the 118-d study. Observed bulk first-order TCE degradation rate constants within the rock matrix were 1.3×10(-8) s(-1). These results clearly show that abiotic dechlorination of TCE is occurring within the rock matrix, despite decades of exposure to TCE. Furthermore, these observed rates of TCE dechlorination are expected to have a substantial impact on TCE migration and uptake/release from rock matrices. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Assessment of long-term impact of formal certified cardiopulmonary resuscitation training program among nurses.

    Science.gov (United States)

    Saramma, P P; Raj, L Suja; Dash, P K; Sarma, P S

    2016-04-01

    Cardiopulmonary resuscitation (CPR) and emergency cardiovascular care guidelines are periodically renewed and published by the American Heart Association. Formal training programs are conducted based on these guidelines. Despite widespread training CPR is often poorly performed. Hospital educators spend a significant amount of time and money in training health professionals and maintaining basic life support (BLS) and advanced cardiac life support (ACLS) skills among them. However, very little data are available in the literature highlighting the long-term impact of these training. To evaluate the impact of formal certified CPR training program on the knowledge and skill of CPR among nurses, to identify self-reported outcomes of attempted CPR and training needs of nurses. Tertiary care hospital, Prospective, repeated-measures design. A series of certified BLS and ACLS training programs were conducted during 2010 and 2011. Written and practical performance tests were done. Final testing was undertaken 3-4 years after training. The sample included all available, willing CPR certified nurses and experience matched CPR noncertified nurses. SPSS for Windows version 21.0. The majority of the 206 nurses (93 CPR certified and 113 noncertified) were females. There was a statistically significant increase in mean knowledge level and overall performance before and after the formal certified CPR training program (P = 0.000). However, the mean knowledge scores were equivalent among the CPR certified and noncertified nurses, although the certified nurses scored a higher mean score (P = 0.140). Formal certified CPR training program increases CPR knowledge and skill. However, significant long-term effects could not be found. There is a need for regular and periodic recertification.

  7. Long-term impact of a preclinical endovascular skills course on medical student career choices.

    Science.gov (United States)

    Lee, Jason T; Son, Ji H; Chandra, Venita; Lilo, Emily; Dalman, Ronald L

    2011-10-01

    Surging interest in the 0 + 5 integrated vascular surgery (VS) residency and successful recruitment of the top students in medical school requires early exposure to the field. We sought to determine the impact of a high-fidelity simulation-based preclinical endovascular skills course on medical student performance and ultimate career specialty choices. Fifty-two preclinical medical students enrolled in an 8-week VS elective course from 2007 to 2009. Students completed a baseline and postcourse survey and performed a renal angioplasty/stent procedure on an endovascular simulator (pretest). A curriculum consisting of didactic teaching covering peripheral vascular disease and weekly mentored simulator sessions concluded with a final graded procedure (posttest). Long-term follow-up surveys 1 to 3 years after course completion were administered to determine ultimate career paths of participants as well as motivating factors for career choice. Objective and subjective performance measured on the simulator and through structured global assessment scales improved in all students from pre- to posttest, particularly with regard to technical skill and overall procedural competency (P choices including surgical subspecialties (64%), radiology (10%), and cardiology (6%). Most respondents indicated major reasons for continued interest in VS were the ability to practice endovascular procedures on the simulator (92%) and mentorship from VS faculty (70%). Basic endovascular skills can be efficiently introduced through a simulation-based curriculum and lead to improved novice performance. Early exposure of preclinical medical students provides an effective teaching and recruitment tool for procedural-based fields, particularly surgical subspecialties. Mentored exposure to endovascular procedures on the simulator positively impacts long-term medical student attitudes toward vascular surgery and ultimate career choices. Copyright © 2011 Society for Vascular Surgery. Published by

  8. Impact of Procedure-Related Complications on Long-term Islet Transplantation Outcome.

    Science.gov (United States)

    Caiazzo, Robert; Vantyghem, Marie-Christine; Raverdi, Violeta; Bonner, Caroline; Gmyr, Valery; Defrance, Frederique; Leroy, Clara; Sergent, Geraldine; Hubert, Thomas; Ernst, Oliver; Noel, Christian; Kerr-Conte, Julie; Pattou, François

    2015-05-01

    Pancreatic islet transplantation offers a promising biotherapy for the treatment of type 1 diabetes, but this procedure has met significant challenges over the years. One such challenge is to address why primary graft function still remains inconsistent after islet transplantation. Several variables have been shown to affect graft function, but the impact of procedure-related complications on primary and long-term graft functions has not yet been explored. Twenty-six patients with established type 1 diabetes were included in this study. Each patient had two to three intraportal islet infusions to obtain 10,000 islet equivalent (IEQ)/kg in body weight, equaling a total of 68 islet infusions. Islet transplantation consisted of three sequential fresh islet infusions within 3 months. Islet infusions were performed surgically or under ultrasound guidance, depending on patient morphology, availability of the radiology suite, and patient medical history. Prospective assessment of adverse events was recorded and graded using "Common Terminology Criteria for adverse events in Trials of Adult Pancreatic Islet Transplantation." There were no deaths or patients dropouts. Early complications occurred in nine of 68 procedures. β score 1 month after the last graft and optimal graft function (β score ≥7) rate were significantly lower in cases of procedure-related complications (P = 0.02, P = 0.03). Procedure-related complications negatively impacted graft function (P = 0.009) and was an independent predictive factor of long-term graft survival (P = 0.033) in multivariate analysis. Complications occurring during radiologic or surgical intraportal islet transplantation significantly impair primary graft function and graft survival regardless of their severity.

  9. STRATEGIC PARTNERSHIP OF UKRAINE: DECLARATIONS AND REALITIES

    Directory of Open Access Journals (Sweden)

    Nataliya Demchenko

    2015-11-01

    Full Text Available The strategic partnership of cooperation is a higher step than conventional relationships. Conditioned by specific interests of the parties, such cooperation is possible between those partners who have mutual territorial claims and have mutual commitment to the territorial integrity. At the same time with many partners (it’s quantity is about 20, Ukraine has no simple partnership and cooperation, a lot of them reseived the status of "strategic partners, but often they are not the states, whose national interests in strategic areas correspondes to the current interests of Ukraine. It should be noted that today among the countries that have been declared as the strategic partners of Ukraine, not all of them support national interests in the present. Ukraine, appeared as an independent state, began use new methods of international cooperation, without adequately developed strategy for their use. Some problems facing the country, can be solved, other must be taken into account in determining its development strategy. Therefore, the subject of the research is global and specific problems that consider issues of economic security and partnership in Ukraine in modern conditions. The objective of the paper is to study options for a strategic partnership in Ukraine by improving the institutional mechanism to coordinate the integration processes. The article is based on studies of foreign and domestic scientists. Practical implications. Formation of effective international cooperation of Ukraine in the context of globalization, the choice of strategic partners on the basis of mutually beneficial cooperation. Results. The analysis of Ukraine’s cooperation with Russia; the features of the largest modern regional associations; reasonably objective need for Ukraine’s integration into the regional associations; recommendations on the necessary measures to accelerate the process of deepening Ukraine’s integration with the EU.

  10. 76 FR 40839 - Changes in Requirements for Specimens and for Affidavits or Declarations of Continued Use or...

    Science.gov (United States)

    2011-07-12

    ... to a registered mark, or an affidavit or declaration of continued use in trademark cases. The... trademark application, an allegation of use, an amendment to a registered mark, or an affidavit or... entity that has a registered trademark could potentially be impacted by the proposed rules. The USPTO...

  11. EPD--environmental product declarations for wood products : an application of life cycle information about forest products

    Science.gov (United States)

    Richard Bergman; Adam Taylor

    2011-01-01

    Transparent and credible environmental labeling of products is vital for a sustainable future. Ecolabeling shows information on the environmental performance of products, processes, and services. This article focuses on one type of ecolabeling referred to as environmental product declarations (EPDs) that provide environmental impact information based on life cycle...

  12. Long-term and short-term action-effect links and their impact on effect monitoring.

    Science.gov (United States)

    Wirth, Robert; Steinhauser, Robert; Janczyk, Markus; Steinhauser, Marco; Kunde, Wilfried

    2018-04-23

    People aim to produce effects in the environment, and according to ideomotor theory, actions are selected and executed via anticipations of their effects. Further, to ensure that an action has been successful and an effect has been realized, we must be able to monitor the consequences of our actions. However, action-effect links might vary between situations, some might apply for a majority of situations, while others might only apply to special occasions. With a combination of behavioral and electrophysiological markers, we show that monitoring of self-produced action effects interferes with other tasks, and that the length of effect monitoring is determined by both, long-term action-effect links that hold for most situations, and short-term action-effect links that emerge from a current setting. Effect monitoring is fast and frugal when these action-effect links allow for valid anticipation of action effects, but otherwise effect monitoring takes longer and delays a subsequent task. Specific influences of long-term and short-term links on the P1/N1 and P3a further allow to dissect the temporal dynamics of when these links interact for the purpose of effect monitoring. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  13. Declaration of the National Forum on Climate Change

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-03

    The purpose of the National Forum on Climate Change was to raise public awareness of the climate change issue and to bring citizens` viewpoint to the debate. The Forum was a unique conference in that the principal attendees, while lay persons as far as climate change is concerned, were members of the Order of Canada. The Order of Canada is an honour bestowed upon upon a relatively small number of Canadian citizens from all walks of life who have made significant contributions to the betterment of their professions or communities or distinguished themselves nationally or internationally. It was the first time that recipients of this high honour were called upon collectively to address an issue of national policy. This declaration was issued at the conclusion of the round table discussions. It expresses their conclusions about climate change, what it is, what are its potential impacts, the scientific uncertainties surrounding the issue, and the actions that can and must be taken by governments and individual citizens to deal with the problem.

  14. The Impact of Government Debt Issuance on Short-Term interest rates in Indonesia

    Directory of Open Access Journals (Sweden)

    Sri Adiningsih

    2009-08-01

    Full Text Available This paper analyzes whether the expansionary fiscal policy funded by issuing debt instruments in financial markets will increase short-term interest rates. If  the expansionary fiscal policy increases interest rates, which decrease private spending especially investment, crowding out occurs. This is interesting because global economic crisis has encouraged many countries to run large budget deficits to stimulate the economy. Indonesia has also run budget deficit during this crisis and even in years before. The impact of such a policy can be significant because Indonesia’s debt market is still narrow and shallow. Therefore, its capability of absorbing the government debt instruments without influencing the private sector funding is limited. This study tests whether the crowding out occurs in Indonesia using a time series econometric model inspired by Cebula and Cuellar’s model. The Cointegration Regression and Error Correction Model (ECM are used in this study. Monthly data from April 2000 to December 2008 are used for overnight real interbank call money interest rates, real net government bond issues in trading, real narrow money supply, real rate of one-month Certificate of Bank Indonesia, growth of Gross Domestic Product, and real net international capital flows. This empirical study shows that the crowding out problem occurred in Indonesia during the period. This indicates that financing budget deficit in Indonesia by issuing debt instruments in the financial markets has a negative impact on the private sector.

  15. THE IMPACT OF ECONOMIC INFRASTRUCTURE ON LONG TERM ECONOMIC GROWTH IN BOTSWANA

    Directory of Open Access Journals (Sweden)

    Strike Mbulawa

    2017-02-01

    Full Text Available The growth rate for the Botswana economy has slowed down in recent years. This has been explained by weak global demand in minerals, subdued commodity prices and persistent electricity supply problems. The government is making efforts to diversify the economy to tap from other sources of growth. The government has come with two initiatives to boast growth: increasing expenditure on roads and improved generation of electricity. Literature has failed to agree on the causal linkage between growth and infrastructure development.  Previous studies employed different measures of infrastructure development and models resulting in conflicting findings. As a point of departure this study uses a log linear model and different measures of growth and infrastructure to examine the link between the two variables in the context of Botswana. Using vector error correction model and Ordinary Least Squares the study finds that long term economic growth is explained by both measures of infrastructure (electricity distribution and maintenance of roads. The impact of the former was more pronounced than the impact of the later. Evidence supports the infrastructure led growth hypothesis.

  16. The impact of short-term heat storage on the ice-albedo feedback loop

    Science.gov (United States)

    Polashenski, C.; Wright, N.; Perovich, D. K.; Song, A.; Deeb, E. J.

    2016-12-01

    The partitioning of solar energy in the ice-ocean-atmosphere environment is a powerful control over Arctic sea ice mass balance. Ongoing transitions of the sea ice toward a younger, thinner state are enhancing absorption of solar energy and contributing to further declines in sea ice in a classic ice-albedo feedback. Here we investigate the solar energy balance over shorter timescales. In particular, we are concerned with short term delays in the transfer of absorbed solar energy to the ice caused by heat storage in the upper ocean. By delaying the realization of ice melt, and hence albedo decline, heat storage processes effectively retard the intra-season ice-albedo feedback. We seek to quantify the impact and variability of such intra-season storage delays on full season energy absorption. We use in-situ data collected from Arctic Observing Network (AON) sea ice sites, synthesized with the results of imagery processed from high resolution optical satellites, and basin-scale remote sensing products to approach the topic. AON buoys are used to monitor the storage and flux of heat, while satellite imagery allows us to quantify the evolution of surrounding ice conditions and predict the aggregate scale solar absorption. We use several test sites as illustrative cases and demonstrate that temporary heat storage can have substantial impacts on seasonal energy absorption and ice loss. A companion to this work is presented by N. Wright at this meeting.

  17. Long-term impacts of battery electric vehicles on the German electricity system

    Science.gov (United States)

    Heinrichs, H. U.; Jochem, P.

    2016-05-01

    The emerging market for electric vehicles gives rise to an additional electricity demand. This new electricity demand will affect the electricity system. For quantifying those impacts a model-based approach, which covers long-term time horizons is necessary in order to consider the long lasting investment paths in electricity systems and the market development of electric mobility. Therefore, we apply a bottom-up electricity system model showing a detailed spatial resolution for different development paths of electric mobility in Germany until 2030. This model is based on a linear optimization which minimizes the discounted costs of the electricity system. We observe an increase of electricity exchange between countries and electricity generated by renewable energy sources. One major result turns out to be that electric vehicles can be integrated in the electricity system without increasing the system costs when a controlled (postponing) charging strategy for electric vehicles is applied. The impact on the power plant portfolio is insignificant. Another important side effect of electric vehicles is their substantial contribution to decreasing CO2 emissions of the German transport sector. Hence, electric mobility might be an integral part of a sustainable energy system of tomorrow.

  18. LONG-TERM EVOLUTION OF DOUBLE WHITE DWARF BINARIES ACCRETING THROUGH DIRECT IMPACT

    International Nuclear Information System (INIS)

    Kremer, Kyle; Kalogera, Vassiliki; Sepinsky, Jeremy

    2015-01-01

    We calculate the long-term evolution of angular momentum in double white dwarf binaries undergoing direct impact accretion over a broad range of parameter space. We allow the rotation rate of both components to vary and account for the exchange of angular momentum between the spins of the white dwarfs and the orbit, while conserving the total angular momentum. We include gravitational, tidal, and mass transfer effects in the orbital evolution, and allow the Roche radius of the donor star to vary with both the stellar mass and the rotation rate. We examine the long-term stability of these systems, focusing in particular on those systems that may be progenitors of AM CVn or SNe Ia. We find that our analysis yields an increase in the predicted number of stable systems compared to that in previous studies. Additionally, we find that by properly accounting for the effects of asynchronism between the donor and the orbit on the Roche-lobe size, we eliminate oscillations in the orbital parameters, which were found in previous studies. Removing these oscillations can reduce the peak mass transfer rate in some systems, keeping them from entering an unstable mass transfer phase

  19. The near-term impacts of carbon mitigation policies on manufacturing industries

    International Nuclear Information System (INIS)

    Morgenstern, Richard D.; Ho Mun; Shih, J.-S.; Zhang Xuehua

    2004-01-01

    Who pays for new policies to reduce carbon dioxide and other greenhouse gas emissions in the United States? This paper considers a slice of the question by examining the near-term impact on domestic manufacturing industries of both upstream (economy-wide) and downstream (electric power industry only) carbon mitigation policies. Detailed Census data on the electricity use of four-digit manufacturing industries are combined with input-output information on inter-industry purchases to paint a detailed picture of carbon use, including effects on final demand. Regional information on electricity supply and use by region is also incorporated. A relatively simple model is developed which yields estimates of the relative burdens within the manufacturing sector of alternative carbon policies. Overall, the principal conclusion is that within the manufacturing sector (which by definition excludes coal production and electricity generation), only a small number of industries would bear a disproportionate short-term burden of a carbon tax or similar policy. Not surprisingly, an electricity-only policy affects very different manufacturing industries than an economy-wide carbon tax

  20. Impact of short‐term, repeated water fasting on the weight of mice

    Directory of Open Access Journals (Sweden)

    Zahra Mishmast

    2014-09-01

    Full Text Available Introduction: Caloric restriction is a strategy applied for weight loss. Water fasting is a popular way for obesity treatment. However, little is known about the impact of water fasting on weight. Therefore, this study was conducted to investigate the effect of short-term, repeated water fasting on the weight of mice. Methods: In this study, the physiological effect of short-term, repeated water fasting on the weight of female mice was evaluated. At 6 weeks of age, mice were randomly assigned to either repeated-fasting or control group (fed ad libitum. Each group consisted of twenty mice. As the fasting period started, the repeated-fasting group had access to only water; animals had free access to food and water on non-fasting days. Body weight of each group before, during, and after the fasting period was recorded. Results: Body weight of the fasting group significantly decreased, unlike the control group. However, the fasting group gained weight rapidly after being re-fed and became significantly heavier than mice in the control group (P

  1. The impact of the long-term playing of musical instruments on the stomatognathic system - review.

    Science.gov (United States)

    Głowacka, Arleta; Matthews-Kozanecka, Maja; Kawala, Maciej; Kawala, Beata

    2014-01-01

    In this article, we have made a review of the influence of playing musical instruments on the formation of malocclusion and TMJ disorders in musicians. Primary attention was paid to the effects of wind and stringed instruments. The aim of the article was the presentation of research and opinions about this problem in the last 25 years. It is reported that long-term and repetitive playing of musical instruments, particularly stringed (violin and viola) and wind instruments can cause dysfunctions of the stomatognathic system. The impact of wind instruments was assessed in terms of the type of mouthpiece. We studied the possibility of repositioning the front teeth and reducing the width of the upper dental arch and overbite. There were also reports on the use of a specific instrument to improve the child's occlusion. Studies have also been performed on the usefulness of relaxation plates in order to improve, and even prevent, dysfunction caused by the constant stress on the same parts of the stomatognathic system. The experiments were mainly based on interviews, dental cast analyses and cephalometric analyses. Additional methods were dynamometer tests and muscle tension palpation.

  2. Short-term impacts of enhanced Greenland freshwater fluxes in an eddy-permitting ocean model

    Directory of Open Access Journals (Sweden)

    R. Marsh

    2010-07-01

    Full Text Available In a sensitivity experiment, an eddy-permitting ocean general circulation model is forced with realistic freshwater fluxes from the Greenland Ice Sheet, averaged for the period 1991–2000. The fluxes are obtained with a mass balance model for the ice sheet, forced with the ERA-40 reanalysis dataset. The freshwater flux is distributed around Greenland as an additional term in prescribed runoff, representing seasonal melting of the ice sheet and a fixed year-round iceberg calving flux, for 8.5 model years. By adding Greenland freshwater fluxes with realistic geographical distribution and seasonality, the experiment is designed to investigate the oceanic response to a sudden and spatially/temporally uniform amplification of ice sheet melting and discharge, rather than localized or gradual changes in freshwater flux. The impacts on regional hydrography and circulation are investigated by comparing the sensitivity experiment to a control experiment, without additional fluxes. By the end of the sensitivity experiment, the majority of additional fresh water has accumulated in Baffin Bay, and only a small fraction has reached the interior of the Labrador Sea, where winter mixed layer depth is sensitive to small changes in salinity. As a consequence, the impact on large-scale circulation is very slight. An indirect impact of strong freshening off the west coast of Greenland is a small anti-cyclonic component to the circulation around Greenland, which opposes the wind-driven cyclonic circulation and reduces net southward flow through the Canadian Archipelago by ~10%. Implications for the post-2000 acceleration of Greenland mass loss are discussed.

  3. Long-Term Human Induced Impacts on Marajó Island Landscapes, Amazon Estuary

    Directory of Open Access Journals (Sweden)

    Denise Schaan

    2010-02-01

    Full Text Available Archaeology is a discipline that can offer a long term perspective on the impacts human societies have had on the environment. Landscape studies are critical for understanding these impacts, because they embrace a dialectical view regarding the relationship between humans and their immediate surroundings. Such studies are well suited to the Amazon basin, a region that has driven much media attention due to astonishing rates of deforestation in certain areas, with likely consequences on the planet’s climate, posing challenges to the survival of the human species for the coming decades. In fact, although much has been said about the impacts of contemporary societies on tropical forest environments, ancient landscape management practices have not yet been considered part of the equation. Thus far, we know that Amerindian societies have been actively transforming their surroundings for millennia. On the eve of European contact, large, complex societies were bringing about long-lasting transformations of landscapes throughout the basin. Conquest and colonization resulted in epidemics, enslavement, and changes to the indigenous economies that managed to survive the genocide. Afterwards, as colonizers would exploit traditional resources leading, in many instances, to their exhaustion, a huge quantity of information on sustainable ways of dealing with certain environments became lost. Traditional knowledge, however, still survives among certain indigenous, peasant (caboclo, and African-Brazilian populations. Documentation of surviving management practices together with the study of the archaeological record could provide valuable information for policy makers. This article examines historical transformations that took place on Marajó Island during the last two millennia and advocates the importance of archaeological research for understanding the historical ecology of landscape change. It is argued that ancient economic strategies, some still being

  4. Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    2011-01-01

    Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723). DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations: Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho; Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

  5. Final Long-Term Management and Storage of Elemental Mercury Environmental Impact Statement Volume1

    Energy Technology Data Exchange (ETDEWEB)

    2011-01-01

    Pursuant to the Mercury Export Ban Act of 2008 (P.L. 110-414), DOE was directed to designate a facility or facilities for the long-term management and storage of elemental mercury generated within the United States. Therefore, DOE has analyzed the storage of up to 10,000 metric tons (11,000 tons) of elemental mercury in a facility(ies) constructed and operated in accordance with the Solid Waste Disposal Act, as amended by the Resource Conservation and Recovery Act (74 FR 31723).DOE prepared this Final Mercury Storage EIS in accordance with the National Environmental Policy Act of 1969 (NEPA), as amended (42 U.S.C. 4321 et seq.), the Council on Environmental Quality (CEQ) implementing regulations (40 CFR 1500–1508), and DOE’s NEPA implementing procedures (10 CFR 1021) to evaluate reasonable alternatives for a facility(ies) for the long-term management and storage of elemental mercury. This Final Mercury Storage EIS analyzes the potential environmental, human health, and socioeconomic impacts of elemental mercury storage at seven candidate locations:Grand Junction Disposal Site near Grand Junction, Colorado; Hanford Site near Richland, Washington; Hawthorne Army Depot near Hawthorne, Nevada; Idaho National Laboratory near Idaho Falls, Idaho;Kansas City Plant in Kansas City, Missouri; Savannah River Site near Aiken, South Carolina; and Waste Control Specialists, LLC, site near Andrews, Texas. As required by CEQ NEPA regulations, the No Action Alternative was also analyzed as a basis for comparison. DOE intends to decide (1) where to locate the elemental mercury storage facility(ies) and (2) whether to use existing buildings, new buildings, or a combination of existing and new buildings. DOE’s Preferred Alternative for the long-term management and storage of mercury is the Waste Control Specialists, LLC, site near Andrews, Texas.

  6. Impact of low-level BK polyomavirus viremia on intermediate-term renal allograft function.

    Science.gov (United States)

    Korth, Johannes; Widera, Marek; Dolff, Sebastian; Guberina, Hana; Bienholz, Anja; Brinkhoff, Alexandra; Anastasiou, Olympia Evdoxia; Kribben, Andreas; Dittmer, Ulf; Verheyen, Jens; Wilde, Benjamin; Witzke, Oliver

    2018-02-01

    BK polyomavirus (BKPyV)-associated nephropathy (PyVAN) is a significant cause of premature renal transplant failure. High-level BKPyV viremia is predictive for PyVAN; however, low-level BKPyV viremia does not necessarily exclude the presence of PyVAN. As data are limited regarding whether or not low-level BKPyV viremia has an effect on intermediate-term graft outcome, this study analyzes the impact of low-level BKPyV viremia on intermediate-term graft function and outcome compared with high-level viremia and non-viremic patients. All renal transplant patients received follow-up examinations at the Department of Nephrology, University Hospital Essen. Patients were screened for BKPyV viremia and stratified into three groups according to their maximum BKPyV load in serum (low-level viremia, high-level viremia, and no viremia). In 142 of 213 (67%) patients, BKPyV was never detected in serum; 42 of 213 (20%) patients were found positive for low-level viremia (≤10 4 copies/mL); and 29 of 213 (13%) patients showed high-level viremia (>10 4 copies/mL). No significant differences regarding transplant function and graft failure were observed between patients without BKPyV viremia (delta estimated glomerular filtration rate [eGFR] +0.1 mL/min [month 1 vs last visit at month 44]) and patients with low-level BKPyV viremia (delta eGFR -1.7 mL/min). In patients with high-level viremia, transplant function was significantly restricted (delta eGFR -6.5 mL/min) compared with low-level viremia until the last visit at 44 ± 9.7 months after transplantation. Although the graft function and graft loss were worse in the high-level viremia group compared with no viremia (eGFR 37 vs 45 mL/min), the difference was not significant. High-level viremia was associated with impaired graft function. In contrast, low-level BKPyV viremia had no significant impact on intermediate-term graft function. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Scientists' declaration to conserve Canada's coastal temperate rainforests

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-06-01

    Immediate cessation of large-scale clearcut logging in the watersheds of the northwest temperate rainforests of Canada has been called for by a group of 400+ scientists, citing the threat of destruction to a variety of plant and animal life and the scientific importance of the area. The declaration affirms the ecological importance of these areas, the disruption and destruction of vulnerable ecosystems of global significance that has already taken place, and urges the government to put an end to clearcut logging in these areas, to be replaced by ecosystem-based forestry which includes areas of biological refuge, maintains the ecological characteristics of the original forests, respects and considers the traditional knowledge of First Nations, and provides for the long-term sustainability of coastal communities who depend on fishing and forestry for their economic and cultural well-being. The declaration includes the names of the 400+ signatories.

  8. Thematic development of declarations on Sustainability in Higher Education

    DEFF Research Database (Denmark)

    Grindsted, Thomas Skou; Holm, Tove

    2012-01-01

    think should be given top priority in order to develop a sustainable society. Hence, the article addresses the following issues: (1) a thematic analysis of the relation between declarations developed by the university sector and those developed by governmental and intergovernmental institutions; (2...... of the international SHE literature reveals no study that deals specifically with the interaction between declarations developed by the university sector and declarations developed by governmental and intergovernmental institutions. An analysis of this type can give us important insights in what themes these parties......) an analysis of themes the two types of declarations might have in common; and if so (3) an analysis of how they have developed during the past decade. The article finds four new themes that previous research has not identified, and shows how the valuation of nature is under reconfiguration in higher education...

  9. Cartagena declaration on renunciation of weapons of mass destruction

    International Nuclear Information System (INIS)

    1992-02-01

    The document reproduces the text of the Cartagena Declaration on Renunciation of Weapons of Mass Destruction, signed by the Presidents of Bolivia, Colombia, Ecuador, Peru and Venezuela at Cartagena de Indias, Colombia, on 4 December 1991

  10. The Brussels Declaration: the need for change in asthma management

    DEFF Research Database (Denmark)

    Holgate, S.; Bisgaard, H.; Bjermer, L.

    2008-01-01

    Asthma is a highly prevalent condition across Europe and numerous guidelines have been developed to optimise management. However, asthma can be neither cured nor prevented, treatment choices are limited and many patients have poorly controlled or uncontrolled asthma. The Brussels Declaration on A...... reviews the evidence supporting the need for change in asthma management and summarises the ten key points contained in the Brussels Declaration Udgivelsesdato: 2008/12......Asthma is a highly prevalent condition across Europe and numerous guidelines have been developed to optimise management. However, asthma can be neither cured nor prevented, treatment choices are limited and many patients have poorly controlled or uncontrolled asthma. The Brussels Declaration...... on Asthma, sponsored by The Asthma, Allergy and Inflammation Research Charity, was developed to call attention to the shortfalls in asthma management and to urge European policy makers to recognise that asthma is a public health problem that should be a political priority. The Declaration urges recognition...

  11. Argentine-Brazilian declaration on common nuclear policy

    International Nuclear Information System (INIS)

    1990-12-01

    The document reproduces the texts of the speeches made by the Presidents of Argentina and Brazil at Foz do Iguacu, Brazil, on 28 November 1990, at the signing of the Argentine-Brazilian Declaration on Common Nuclear Policy

  12. New procedure for declaring accidents resulting in bodily injuries

    CERN Document Server

    2014-01-01

    The HR Department would like to remind members of personnel that, according to Administrative Circular No. 14 (Rev. 3), entitled “Protection of members of the personnel against the financial consequences of illness, accident and incapacity for work”, accidents resulting in bodily injuries and presumed to be of an occupational nature should, under normal circumstances, be declared within 10 working days of the accident having occurred, accompanied by a medical certificate. In an effort to streamline procedures, occupational accident declarations should be made via EDH using the “declaration of occupational accident” electronic form. For the declaration of non-occupational accidents resulting in bodily injuries of members of the CERN Health Insurance Scheme (CHIS), a new paper form has been elaborated that can be downloaded from the CHIS website and is also available from the UNIQA Helpdesk in the Main Building. If you encounter technical difficulties with these new ...

  13. Assessing the added value of the recent declaration on unregulated fishing for sustainable governance of the central Arctic Ocean

    DEFF Research Database (Denmark)

    Shephard, Grace Elizabeth; Dalen, Kari; Peldszus, Regina

    2016-01-01

    The ‘Declaration concerning the prevention of unregulated high seas fishing in the central Arctic Ocean’ signed by the Arctic 5 nations, limits unregulated high seas fishing in the central part of the Arctic Ocean, and holds potential social, economic and political impacts for numerous stakeholders....... In this paper, the four Interim Measures in the Declaration are discussed and what value these measures bring beyond the existing international agreements is explored. It is found that even though the Declaration fills a gap in the management of potential fish stocks in the central Arctic Ocean, adopts...... understanding of the fisheries as well as the broader Arctic environment. Furthermore, the research generated by this measure will provide an important decision base for both regulation and management of human activity in the Arctic....

  14. Accounting for change in declarative memory: A cognitive neuroscience perspective

    OpenAIRE

    Richmond, Jenny; Nelson, Charles A.

    2007-01-01

    The medial temporal lobe memory system matures relatively early and supports rudimentary declarative memory in young infants. There is considerable development, however, in the memory processes that underlie declarative memory performance during infancy. Here we consider age-related changes in encoding, retention, and retrieval in the context of current knowledge about the brain systems that may underlie these memory processes. While changes in infants’ encoding may be attributed to rapid mye...

  15. A shared resource between declarative memory and motor memory

    OpenAIRE

    Keisler, Aysha; Shadmehr, Reza

    2010-01-01

    The neural systems that support motor adaptation in humans are thought to be distinct from those that support the declarative system. Yet, during motor adaptation changes in motor commands are supported by a fast adaptive process that has important properties (rapid learning, fast decay) that are usually associated with the declarative system. The fast process can be contrasted to a slow adaptive process that also supports motor memory, but learns gradually and shows resistance to forgetting....

  16. The declaration regime: An efficient tool to improve control and protection of nuclear materials in France

    International Nuclear Information System (INIS)

    Pillette-Cousin, L.

    2001-01-01

    gathers all the declaration forms fulfilled by declarants. It allows to identify lacks of consistency in the stocks inventoried and declared by operators. Implementation is also ensured by on-site inspections, carried out by sworn and accredited inspectors under the authority of the Ministry for Industry. Checks are carried out notably on the compliance of the physical protection arrangements made by the operator and on the exhaustiveness of physical inventories of nuclear materials. In this way, every year, tens of items and tens of kilograms of nuclear material (mainly depleted uranium) are put back into a controlled environment. Even if the nuclear materials held by declarants are of low sensitivity as far as proliferation is concerned, a total absence of regulations on the low quantities concerned might lead to an increased attractiveness for unauthorized uses. The declaration regime is a balanced approach between exemption and licensing. Moreover, good practices in terms of control and physical protection of nuclear materials held by declarants reduces the occurrence of incidents related to losses or thefts of equipment or products containing nuclear materials. (author)

  17. Impact of long-term land application of broiler litter on environmentally related soil properties

    Energy Technology Data Exchange (ETDEWEB)

    Kingery, W.L. [Mississippi State Univ., MS (United States); Wood, C.W.; Mullins, G.L. [Auburn Univ., AL (United States)] [and others

    1994-01-01

    The largest portion of Alabama`s rapidly growing poultry industry is geographically concentrated in the Sand Mountain region of northern Alabama. The result is that large amounts of waste are applied to relatively small areas of agricultural soils. A study was conducted to determine the effects of long-term broiler waste (litter) application on environmentally related soil conditions in the region. The region has an average annual rainfall of 1325 mm, which is evenly distributed throughout the year, a thermic temperature regime, and soils in the region are of the Ultisol order. In each of four major broiler-producing counties, three pairs of sites consisting of long-term (15-28 yr) littered and nonlittered fields on matching soil series and maintained under perennial tall fescue (Festuca arundinacea Schreb.) were sampled. Soil cores were taken to 3 m or lithic contact and depth-incremented samples (0-15, 15-30, and each subsequent 30-cm interval) were analyzed for organic C, total N, NO{sub 3}-N, pH, electrical conductivity, and acid-extractable P, K, Ca, Mg, Co, and Zn. Litter application increased organic C and total N to depths of 15 and 30 cm, respectively, as compared with nonlittered soils, whereas pH was 0.5 units higher to a depth of 60 cm under littered soils. Significant accumulation of NO{sub 3}N was found in littered soils to or near bedrock. Extractable P concentrations in littered soils were more than six times greater than in nonlittered soils to a depth of 60 cm. Elevated levels of extractable K, Ca, and Mg to depths greater than 60 cm also were found as a result of long-term litter use. Extractable Cu and Zn had accumulated in littered soils to a depth of 45 cm. These findings indicate that long-term land application of broiler litter, at present rates, has altered soil chemical conditions and has created a potential for adverse environmental impacts in the Sand Mountain region of Alabama. 43 refs., 6 figs., 3 tabs.

  18. Effects of low doses of alcohol on declarative memory in humans

    Directory of Open Access Journals (Sweden)

    José Arturo Bríñez-Horta

    2011-09-01

    Full Text Available This study assessed the effect of low doses of alcohol on two elements of explicit or declarative memory, in 16 participants, 8 women and 8 men, with The Weschler Memory Scale III Text Test. A factorial 2 * 4 counterbalanced with repeated measures design was used. There were no statistically significant differences by gender, but there were differences among doses, specially 0.150 g / Kg., which reduced episodic and semantic retrieval, between 43.9 and 62.9 % of effect strength, in intermediate term memory. These results provided evidence that alcohol in low doses has a more pronounced effect in semantic, rather than episodic memory, in the middle term

  19. On the long-term impact of emissions from central European cities on regional air quality

    Directory of Open Access Journals (Sweden)

    P. Huszar

    2016-02-01

    Full Text Available For the purpose of qualifying and quantifying the impact of urban emission from Central European cities on the present-day regional air quality, the regional climate model RegCM4.2 was coupled with the chemistry transport model CAMx, including two-way interactions. A series of simulations was carried out for the 2001–2010 period either with all urban emissions included (base case or without considering urban emissions. Further, the sensitivity of ozone production to urban emissions was examined by performing reduction experiments with −20 % emission perturbation of NOx and/or non-methane volatile organic compounds (NMVOC. The modeling system's air quality related outputs were evaluated using AirBase, and EMEP surface measurements showed reasonable reproduction of the monthly variation for ozone (O3, but the annual cycle of nitrogen dioxide (NO2 and sulfur dioxide (SO2 is more biased. In terms of hourly correlations, values achieved for ozone and NO2 are 0.5–0.8 and 0.4–0.6, but SO2 is poorly or not correlated at all with measurements (r around 0.2–0.5. The modeled fine particulates (PM2.5 are usually underestimated, especially in winter, mainly due to underestimation of nitrates and carbonaceous aerosols. European air quality measures were chosen as metrics describing the cities emission impact on regional air pollution. Due to urban emissions, significant ozone titration occurs over cities while over rural areas remote from cities, ozone production is modeled, mainly in terms of number of exceedances and accumulated exceedances over the threshold of 40 ppbv. Urban NOx, SO2 and PM2.5 emissions also significantly contribute to concentrations in the cities themselves (up to 50–70 % for NOx and SO2, and up to 60 % for PM2.5, but the contribution is large over rural areas as well (10–20 %. Although air pollution over cities is largely determined by the local urban emissions, considerable (often a few tens of % fraction of the

  20. Fuel consumption: short term and long term price impacts per population type; Consommation de carburant: effets des prix a court et a long termes par type de population

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    This report presents assessments of the price sensitivity of household fuel consumption. After a literature review on price-elasticity assessments and the use of pseudo-panels, the investigation analyses the deciding factors of the household fuel expense and its evolution between 1985 and 2006. It proposes a short term price-elasticity assessment based on the most recent survey, and also proposes price-elasticity assessments for sub-populations, notably in terms of income level or location (rural or urban areas)

  1. Nonlinear feedback in a six-dimensional Lorenz model: impact of an additional heating term

    Science.gov (United States)

    Shen, B.-W.

    2015-12-01

    In this study, a six-dimensional Lorenz model (6DLM) is derived, based on a recent study using a five-dimensional (5-D) Lorenz model (LM), in order to examine the impact of an additional mode and its accompanying heating term on solution stability. The new mode added to improve the representation of the streamfunction is referred to as a secondary streamfunction mode, while the two additional modes, which appear in both the 6DLM and 5DLM but not in the original LM, are referred to as secondary temperature modes. Two energy conservation relationships of the 6DLM are first derived in the dissipationless limit. The impact of three additional modes on solution stability is examined by comparing numerical solutions and ensemble Lyapunov exponents of the 6DLM and 5DLM as well as the original LM. For the onset of chaos, the critical value of the normalized Rayleigh number (rc) is determined to be 41.1. The critical value is larger than that in the 3DLM (rc ~ 24.74), but slightly smaller than the one in the 5DLM (rc ~ 42.9). A stability analysis and numerical experiments obtained using generalized LMs, with or without simplifications, suggest the following: (1) negative nonlinear feedback in association with the secondary temperature modes, as first identified using the 5DLM, plays a dominant role in providing feedback for improving the solution's stability of the 6DLM, (2) the additional heating term in association with the secondary streamfunction mode may destabilize the solution, and (3) overall feedback due to the secondary streamfunction mode is much smaller than the feedback due to the secondary temperature modes; therefore, the critical Rayleigh number of the 6DLM is comparable to that of the 5DLM. The 5DLM and 6DLM collectively suggest different roles for small-scale processes (i.e., stabilization vs. destabilization), consistent with the following statement by Lorenz (1972): "If the flap of a butterfly's wings can be instrumental in generating a tornado, it can

  2. The Short-Term Impacts of the Philadelphia Beverage Tax on Beverage Consumption.

    Science.gov (United States)

    Zhong, Yichen; Auchincloss, Amy H; Lee, Brian K; Kanter, Genevieve P

    2018-04-11

    On January 1, 2017, Philadelphia implemented a beverage tax of $0.015/ounce on sugar ("regular") and sugar-substitute ("diet") beverages. The purpose of this study was to evaluate the immediate impact of the tax on residents' consumption of soda, fruit drinks, energy drinks, and bottled water. A repeat cross-sectional study design used data from a random-digit-dialing phone survey during a no-tax period (December 6-31, 2016) and a tax period (January 15-February 31, 2017) among 899 respondents in Philadelphia, Pennsylvania, and 878 respondents in three nearby comparison cities. Survey questions included frequency and volume of bottled water and beverages. Outcomes were daily consumption, and 30-day consumption frequency and volume. Propensity score-weighted difference-in-differences regression was used to control for secular time trend and confounding. Covariates were sociodemographics, BMI, health status, smoking, and alcohol use. Analyses were conducted in 2017. Within the first 2 months of tax implementation, relative to the comparison cities, in Philadelphia the odds of daily consumption of regular soda was 40% lower (OR=0.6, 95% CI=0.37, 0.97); energy drink was 64% lower (OR=0.36, 95% CI=0.17, 0.76); bottled water was 58% higher (OR=1.58, 95% CI=1.13, 2.20); and the 30-day regular soda consumption frequency was 38% lower (ratio of consumption frequency=0.62, 95% CI=0.40, 0.98). Early results suggest that the tax influenced daily consumption of regular soda, energy drinks, and bottled water. Future studies are needed to evaluate longer-term impact of the tax on sugared beverage consumption and substitutions. Copyright © 2018 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  3. Impact of short-term meditation and expectation on executive brain functions.

    Science.gov (United States)

    Prätzlich, Martin; Kossowsky, Joe; Gaab, Jens; Krummenacher, Peter

    2016-01-15

    Meditation improves executive functions such as attention and working memory processes. However, it remains unclear to what extent contextual effects contribute to these improvements, since the role of meditation-associated expectations has not been investigated so far. In a randomized, single-blind, deceptive, between-subject design we compared the impact of short-term meditation (MG) on executive functioning with an expectation (ECG) and a passive control group (CG) as well as the effect of positive and negative outcome expectations. Fifty-nine healthy meditation-naïve volunteers participated on three consecutive days (20 min/session). Five groups were examined: 2 MGs, 2 ECGs and 1 CG. While one MG and one ECG were given positive suggestions concerning the effect of meditation on attention, the other two groups were given negative suggestions. MGs practised a focused attention meditation technique; ECGs were told that they were practising meditation but were given instructions for a sham meditation. CG participants sat in silence with their eyes closed. Interference control (Stroop task), selective sustained attention (d2 task), figural and verbal fluency measures of executive functions were assessed. Results indicate that suggestions have a substantial impact on interference control and verbal fluency, with positive suggestions leading to an increase in performance, whereas negative suggestions impeded improvement. This proof of concept study demonstrates the importance of the implementation of a credible ECG to elucidate context effects in meditation processes. It also indicates that suggestions can modulate the small effect of meditation on verbal fluency. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Impacts of informal caregiver availability on long-term care expenditures in OECD countries.

    Science.gov (United States)

    Yoo, Byung-Kwang; Bhattacharya, Jay; McDonald, Kathryn M; Garber, Alan M

    2004-12-01

    To quantify the effects of informal caregiver availability and public funding on formal long-term care (LTC) expenditures in developed countries. Secondary data were acquired for 15 Organization for Economic Cooperation and Development (OECD) countries from 1970 to 2000. Secondary data analysis, applying fixed- and random-effects models to time-series cross-sectional data. Outcome variables are inpatient or home heath LTC expenditures. Key explanatory variables are measures of the availability of informal caregivers, generosity in public funding for formal LTC, and the proportion of the elderly population in the total population. Aggregated macro data were obtained from OECD Health Data, United Nations Demographic Yearbooks, and U.S. Census Bureau International Data Base. Most of the 15 OECD countries experienced growth in LTC expenditures over the study period. The availability of a spouse caregiver, measured by male-to-female ratio among the elderly, is associated with a $28,840 (1995 U.S. dollars) annual reduction in formal LTC expenditure per additional elderly male. Availability of an adult child caregiver, measured by female labor force participation and full-time/part-time status shift, is associated with a reduction of $310 to $3,830 in LTC expenditures. These impacts on LTC expenditure vary across countries and across time within a country. The availability of an informal caregiver, particularly a spouse caregiver, is among the most important factors explaining variation in LTC expenditure growth. Long-term care policies should take into account behavioral responses: decreased public funding in LTC may lead working women to leave the labor force to provide more informal care.

  5. Impact of Visceral Obesity and Sarcopenia on Short-Term Outcomes After Colorectal Cancer Surgery.

    Science.gov (United States)

    Chen, Wei-Zhe; Chen, Xiao-Dong; Ma, Liang-Liang; Zhang, Feng-Min; Lin, Ji; Zhuang, Cheng-Le; Yu, Zhen; Chen, Xiao-Lei; Chen, Xiao-Xi

    2018-06-01

    With the increased prevalence of obesity and sarcopenia, those patients with both visceral obesity and sarcopenia were at higher risk of adverse outcomes. The aim of this study was to ascertain the combined impact of visceral obesity and sarcopenia on short-term outcomes in patients undergoing colorectal cancer surgery. We conducted a prospective study from July 2014 to February 2017. Patients' demographic, clinical characteristics, physical performance, and postoperative short-term outcomes were collected. Patients were classified into four groups according to the presence of sarcopenia or visceral obesity. Clinical variables were compared. Univariate and multivariate analyses evaluating the risk factors for postoperative complications were performed. A total of 376 patients were included; 50.8 and 24.5% of the patients were identified as having "visceral obesity" and "sarcopenia," respectively. Patients with sarcopenia and visceral obesity had the highest incidence of total, surgical, and medical complications. Patients with sarcopenia or/and visceral obesity all had longer hospital stays and higher hospitalization costs. Age ≥ 65 years, visceral obesity, and sarcopenia were independent risk factors for total complications. Rectal cancer and visceral obesity were independent risk factors for surgical complications. Age ≥ 65 years and sarcopenia were independent risk factors for medical complications. Laparoscopy-assisted operation was a protective factor for total and medical complications. Patients with both visceral obesity and sarcopenia had a higher complication rate after colorectal cancer surgery. Age ≥ 65 years, visceral obesity, and sarcopenia were independent risk factors for total complications. Laparoscopy-assisted operation was a protective factor.

  6. Long term PM2.5 estimation and its impact on human health in Beijing, China

    Science.gov (United States)

    Zheng, Sheng; Pozzer, Andrea; Cao, Chunxiang

    2014-05-01

    Due to the economic growth and urbanization, the emissions of pollutants have increased significantly in the North China Plain (NCP). Beijing, the capital of China, is located at the northern tip of NCP, and it is considered one of the most densely populated cities with the poorest air quality. This is of major concerns, because of the impact of high pollutants concentration on human health. The present study analyses the characteristics of AOD and the particulate matter with diameter health in the central Beijing areas. We acquire AOD from Aerosol Robotic Network (AERONET) in Beijing from 2001 to 2012. The AOD data are fitted with a lognormal distribution, and the 95% of the cumulative probability is used as the threshold for episodes of high AOD. Most episodes occur in summer, mostly in June, though this is combined with high precipitation. Episodes of high AOD caused by coarse pollutants occur only in March and April, and they are mostly caused by dust from the north. According to wind direction, wind speed, boundary layer height (BLH) and pollutant emission distribution, episodes of high AOD are due to the anthropogenic pollutants from the south (Hebei province). Based on ground PM2.5 observation from the US embassy in Beijing from 2010 to 2011, we establish a relationship between PM2.5and AERONET AOD, including BLH and relative humidity (RH) correction. Thanks to this method, 12 years of PM2.5 are estimated for the Beijing central area, allowing the estimation of long term concentrations of this pollutant. Since there is no obvious difference among the daily PM2.5 of six stations lying in Chaoyang, Dongcheng, and Xicheng district, we use the daily PM2.5 from US embassy station to represent the PM2.5 concentration in these three districts, and calculate yearly premature mortality due to long term exposure to PM2.5among the population with an age of ≥ 30 yr in these three districts.

  7. Impact of maternal age on delivery outcomes following spontaneous labour at term.

    Science.gov (United States)

    Omih, Edwin Eseoghene; Lindow, Stephen

    2016-10-01

    Pregnancy in women of advancing maternal age is linked to incrementally worsening perinatal outcome. The aim of this study is to assess the impact of maternal age on delivery outcome in women that spontaneously labour at term. This was a retrospective study of women that spontaneously labour at term. Women with singletons in spontaneous onset labour beyond 37 weeks of gestation were divided into five maternal age groups: 35 years by their age at delivery. The main outcome variables are augmentation of labour, caesarean section, assisted vaginal delivery, and perineal trauma, while admission of the newborn into the neonatal unit within 24 h following delivery was the secondary outcome measure. A total of 30,022 met the inclusion criteria with primiparae and multiparae accounting for 46 and 54%, respectively. Increasing age in primiparae was associated with; augmentation of labour OR 2.05 (95% CI 1.73-2.43), second degree perineal tear 1.35 (1.12-1.61), assisted vaginal delivery 1.92 (1.53-2.41) and caesarean section 4.23 (3.19-5.12). While that for multiparae; augmentation of labour OR 1.93 (1.05-3.52), perineal trauma 2.50 (1.85-3.34), assisted vaginal delivery 4.95 (91.82-13.35) and caesarean section 1.64 (1.13-2.38). The secondary outcome measure did not reach statistical significance. Increasing maternal age is an independent risk factor for operative delivery, and perineal trauma. However, maternal age has no significant effect on admission of infants into the NICU during the first 24 h following delivery.

  8. Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome

    Energy Technology Data Exchange (ETDEWEB)

    Jakobsson, H.; Jernberg, C.; Andersson, A.F.; Sjolund-Karlsson, M.; Jansson, J.K.; Engstrand, L.

    2010-01-15

    Antibiotic administration is the standard treatment for the bacterium Helicobacter pylori, the main causative agent of peptic ulcer disease and gastric cancer. However, the long-term consequences of this treatment on the human indigenous microbiota are relatively unexplored. Here we studied short- and long-term effects of clarithromycin and metronidazole treatment, a commonly used therapy regimen against H. pylori, on the indigenous microbiota in the throat and in the lower intestine. The bacterial compositions in samples collected over a four year period were monitored by analyzing the 16S rRNA gene using 454-based pyrosequencing and terminal-restriction fragment length polymorphism (T-RFLP). While the microbial communities of untreated control subjects were relatively stable over time, dramatic shifts were observed one week after antibiotic treatment with reduced bacterial diversity in all treated subjects in both locations. While the microbiota of the different subjects responded uniquely to the antibiotic treatment some general trends could be observed; such as a dramatic decline in Actinobacteria in both throat and feces immediately after treatment. Although the diversity of the microbiota subsequently recovered to resemble the pre treatment states, the microbiota remained perturbed in some cases for up to four years post treatment. In addition, four years after treatment high levels of the macrolide resistance gene erm(B) were found, indicating that antibiotic resistance, once selected for, can persist for longer periods of time than previously recognized. This highlights the importance of a restrictive antibiotic usage in order to prevent subsequent treatment failure and potential spread of antibiotic resistance.

  9. Impact of glaciations on the long-term erosion in Southern Patagonian Andes

    Science.gov (United States)

    Simon-Labric, Thibaud; Herman, Frederic; Baumgartner, Lukas; Shuster, David L.; Braun, Jean; Reiners, Pete W.; Valla, Pierre G.; Leuthold, Julien

    2014-05-01

    The Southern Patagonian Andes are an ideal setting to study the impact of Late-Cenozoic climate cooling and onset of glaciations impact on the erosional history of mountain belts. The lack of tectonic activity during the last ~12 Myr makes the denudation history mainly controlled by surface processes, not by tectonics. Moreover, the glaciations history of Patagonia shows the best-preserved records within the southern hemisphere (with the exception of Antarctica). Indeed, the dry climate on the leeward side of Patagonia and the presence of lava flows interbedded with glacial deposits has allowed an exceptional preservation of late Cenozoic moraines with precise dating using K-Ar analyses on lava flow. The chronology of moraines reveals a long history covering all the Quaternary, Pliocene, and up to the Upper Miocene. The early growth of large glaciers flowing on eastern foothills started at ~7-6 Myr, while the maximum ice-sheet extent dates from approximately 1.1 Myr. In order to quantify the erosion history of the Southern Patagonian Andes and compare it to the glaciations sediment record, we collected samples along an age-elevation profile for low-temperature thermochronology in the eastern side of the mountain belt (Torres del Paine massif). The (U-Th)/He age-elevation relationship shows a clear convex shape providing an apparent long-term exhumation rate of ~0.2 km/Myr followed by an exhumation rate increase at ~6 Myr. Preliminary results of 4He/3He thermochronometry for a subset of samples complete the erosion history for the Plio-Pleistocene epoch. We used inverse procedure predicting 4He distributions within an apatite grain using a radiation-damage and annealing model to quantify He-diffusion kinetics in apatite. The model also allows quantifying the impact of potential U-Th zonation throughout each apatite crystal. Inversion results reveal a denudation history composed by a pulse of denudation at ~6 Ma, as suggested by the age-elevation relationship

  10. Feedback on the significant events of radiation protection declared to Asn in external radiotherapy, from necessity of a quality management to the service of risk management; Retour d'experience sur les evenements significatifs de radioprotection declares a l'asn en radiotherapie externe, de la necessite d'un management de la qualite au service de la gestion des risques

    Energy Technology Data Exchange (ETDEWEB)

    Marchal, C. [ASN, 75 - Paris (France); Garandel, S.; Godet, J.L. [Angers Univ., 49 (France)

    2009-10-15

    The declaration of events in the perspective of a experience feedback towards the professionals contributes to improve the treatments safety. The stakes in term of treatments safety is in the capitalization of these experience feedbacks from declarations. Well, the publication of regulatory obligations in matter of quality assurance and their appropriation by the whole of medical teams should improve the treatment safety and and increase their quality. To the end, without being unaware of the current difficulties encountered y some centers because of the lack of radio physicists, the approach of significant events declaration and risk analysis should allow to the french radiotherapy to become an international reference. (N.C.)

  11. Long-term impacts of coral bleaching events on the world's warmest reefs.

    Science.gov (United States)

    Burt, John; Al-Harthi, Suaad; Al-Cibahy, Ashraf

    2011-10-01

    The southern Arabian Gulf houses some of the most thermally tolerant corals on earth, but severe bleaching in the late 1990s caused widespread mortality. More than a decade later, corals still dominated benthos (mean: 40 ± 3% cover on 10 sites spanning > 350 km; range: 11.0-65.6%), but coral communities varied spatially. Sites to the west generally had low species richness and coral cover (mean: 3.2 species per transect, 31% cover), with Porites dominated communities (88% of coral) that are distinct from more diverse and higher cover eastern sites (mean: 10.3 species per transect, 62% cover). These patterns reflect both the more extreme bleaching to the west in the late 1990s as well as the higher faviid dominated recruitment to the east in subsequent years. There has been limited recovery of the formerly dominant Acropora, which now represents bleaching can have substantial long-term impacts on coral communities, even in areas with corals tolerant to environmental extremes. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. Application of washed MSWI fly ash in cement composites: long-term environmental impacts.

    Science.gov (United States)

    Yang, Zhenzhou; Tian, Sicong; Liu, Lili; Wang, Xidong; Zhang, Zuotai

    2018-04-01

    In the present study, long-term environmental impacts of compact and ground cement composites, in which 30 wt.% of cement was replaced by washed municipal solid wastes incineration (MSWI) fly ash, were investigated for use in building industry. Consecutive leaching tests over a time span of 180 days were performed in acid water, deionized water, and saline water, respectively, with the accumulative concentration of different elements determined in the leachate. Different leaching behaviors are observed among different potential toxic elements (PTEs). For instance, higher concentrations of V in the leachate were observed from the compact cement composites than those from the ground ones. The concentration of Ba in the leachate increased with the decrease of particle size of the cement composites, and an initial increase in the leaching efficiency of Sn was followed by a clear decline with the leaching time. In addition, kinetic study revealed that the leaching behaviors of potential toxic elements follow a second-order model. The results demonstrated that the addition of washed MSWI fly ash into cement can contribute to the attrition resistance, indicating that the washed MSWI fly ash could be a promising alternative for cement as supplementary building materials.

  13. Assessment of the economic impact of environmental constraints on short-term hydropower plant operation

    International Nuclear Information System (INIS)

    Perez-Diaz, Juan I.; Wilhelmi, Jose R.

    2010-01-01

    Environmental constraints imposed on hydropower plant operation are usually given in the form of minimum environmental flows and, in some cases, in the form of maximum and minimum rates of change of flows, or ramping rates. Environmental constraints reduce the amount of water available to produce electricity and limit the contribution of peak hydropower plants to adapting the power supply to the demand and to providing certain ancillary services to the electrical grid, such as spinning reserve or load-frequency control. The objective of this paper is to assess the economic impact of environmental constraints on short-term hydropower plant operation. For that purpose, a revenue-driven daily optimization model based on mixed integer linear programming is used. The model considers the head variation and its influence on the units' efficiency, as well as the option of starting-up or shutting-down the plant at any hour of the day, should it be advantageous, while releasing the environmental flow through the bottom outlets. In order to illustrate the applicability of the methodology, it is applied in a real hydropower plant under different operating conditions and environmental constraints. (author)

  14. Decreased term and postterm birthweight in the United States: impact of labor induction.

    Science.gov (United States)

    Zhang, Xun; Joseph, K S; Kramer, Michael S

    2010-08-01

    We sought to assess recent trends in falling mean birthweight (BW) and gestational age (GA) among US non-Hispanic white singleton live births >or=37 weeks of gestation and the contribution of increased rates of induction to these trends. This was an ecological study based on US vital statistics from 1992 through 2003. From 1992 through 2003, mean BW fell by 37 g, mean GA by 3 days, and macrosomia rates by 25%. Rates of induction nearly doubled from 14% to 27%. Our ecological state-level analysis showed that the increased rate of induction was significantly associated with reduced mean BW (r = -0.54; 95% confidence interval [CI], -0.71 to -0.29), mean GA (r = -0.44; 95% CI, -0.65 to -0.17), and rate of macrosomia (r = -0.55; 95% CI, -0.74 to -0.32). Increasing use of induction is a likely cause of the observed recent declines in BW and GA. The impact of these trends on infant and long-term health warrants attention and investigation. Copyright (c) 2010 Mosby, Inc. All rights reserved.

  15. Mid-term evaluation of the Climate Change Action Fund: Science, Impacts and Adaptation (SIA) block

    International Nuclear Information System (INIS)

    2001-11-01

    In 1998, the Climate Change Action Fund was established by the Government of Canada. Its budget represented 150 million dollars over a three year period, and was an additional 625 million dollars in the federal budget of February 2000 was allocated for climate change initiatives, of which 150 million dollars were earmarked over a three year period to the Climate Change Action Fund. To provide input for Treasury Board Submissions looking for funding approval in the future, it was necessary to conduct a mid-term evaluation focused on program performance to date. The period covered by the evaluation was September 2000 to the end of January 2001. This report examined the performance of the Science, Impact and Adaptation Block (SIA). Based on a series of interviews with representatives of Block managers, Technical and Executive Policy Committees, successful applicants, unsuccessful applicants and peer reviewers, as well as a review of the documentation maintained by SIA, it addressed the following issues: Block relevance, progress/success to date, and effectiveness in meeting the objectives. It was determined that the objectives displayed relevance to the climate change agenda of the federal government, progress to date was considered satisfactory, and most of the objectives should be met in a timely fashion. A summary of the findings was included in this document along with recommendations pertaining to the findings. 3 tabs., 1 fig

  16. An exploration of the longer-term impacts of community participation in rural health services design.

    Science.gov (United States)

    Farmer, Jane; Currie, Margaret; Kenny, Amanda; Munoz, Sarah-Anne

    2015-09-01

    This article explores what happened, over the longer term, after a community participation exercise to design future rural service delivery models, and considers perceptions of why more follow-up actions did or did not happen. The study, which took place in 2014, revisits three Scottish communities that engaged in a community participation research method (2008-2010) intended to design rural health services. Interviews were conducted with 22 citizens, healthcare practitioners, managers and policymakers all of whom were involved in, or knew about, the original project. Only one direct sustained service change was found - introduction of a volunteer first responder scheme in one community. Sustained changes in knowledge were found. The Health Authority that part-funded development of the community participation method, through the original project, had not adopted the new method. Community members tended to attribute lack of further impact to low participation and methods insufficiently attuned to the social nuances of very small rural communities. Managers tended to blame insufficient embedding in the healthcare system and issues around power over service change and budgets. In the absence of convincing formal community governance mechanisms for health issues, rural health practitioners tended to act as conduits between citizens and the Health Authority. The study provides new knowledge about what happens after community participation and highlights a need for more exploration. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Assessment of the economic impact of environmental constraints on short-term hydropower plant operation

    Energy Technology Data Exchange (ETDEWEB)

    Perez-Diaz, Juan I.; Wilhelmi, Jose R. [Department of Hydraulic and Energy Engineering, Technical University of Madrid (UPM), c/Profesor Aranguren s/n, 28040 Madrid (Spain)

    2010-12-15

    Environmental constraints imposed on hydropower plant operation are usually given in the form of minimum environmental flows and, in some cases, in the form of maximum and minimum rates of change of flows, or ramping rates. Environmental constraints reduce the amount of water available to produce electricity and limit the contribution of peak hydropower plants to adapting the power supply to the demand and to providing certain ancillary services to the electrical grid, such as spinning reserve or load-frequency control. The objective of this paper is to assess the economic impact of environmental constraints on short-term hydropower plant operation. For that purpose, a revenue-driven daily optimization model based on mixed integer linear programming is used. The model considers the head variation and its influence on the units' efficiency, as well as the option of starting-up or shutting-down the plant at any hour of the day, should it be advantageous, while releasing the environmental flow through the bottom outlets. In order to illustrate the applicability of the methodology, it is applied in a real hydropower plant under different operating conditions and environmental constraints. (author)

  18. Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids.

    Science.gov (United States)

    Saudan, Christophe; Baume, Norbert; Emery, Caroline; Strahm, Emmanuel; Saugy, Martial

    2008-06-10

    Tribulus terrestris is a nutritional supplement highly debated regarding its physiological and actual effects on the organism. The main claimed effect is an increase of testosterone anabolic and androgenic action through the activation of endogenous testosterone production. Even if this biological pathway is not entirely proven, T. terrestris is regularly used by athletes. Recently, the analysis of two female urine samples by GC/C/IRMS (gas chromatography/combustion/isotope-ratio-mass-spectrometry) conclusively revealed the administration of exogenous testosterone or its precursors, even if the testosterone glucuronide/epitestosterone glucuronide (T/E) ratio and steroid marker concentrations were below the cut-off values defined by World Anti-Doping Agency (WADA). To argue against this adverse analytical finding, the athletes recognized having used T. terrestris in their diet. In order to test this hypothesis, two female volunteers ingested 500 mg of T. terrestris, three times a day and for two consecutive days. All spot urines were collected during 48 h after the first intake. The (13)C/(12)C ratio of ketosteroids was determined by GC/C/IRMS, the T/E ratio and DHEA concentrations were measured by GC/MS and LH concentrations by radioimmunoassay. None of these parameters revealed a significant variation or increased above the WADA cut-off limits. Hence, the short-term treatment with T. terrestris showed no impact on the endogenous testosterone metabolism of the two subjects.

  19. Health impact of exposure to fine particles. Epidemiology of short-term effects

    International Nuclear Information System (INIS)

    Peters, Annette; Wichmann, H.-Erich; Univ. Muenchen; Heinrich, Joachim

    2002-01-01

    Epidemiological studies on short-term effects of fine particles are investigating whether morbidity or mortality increase on days with high particle concentrations. Multi-center studies have shown on a daily basis that there is an increase in morbidity and/or mortality in association with particle concentrations. Studies on the effects of particles on the respiratory tract have indicated that there is an impact of particles at their place of deposition. In addition, numerous studies have revealed that particles also have effects on the cardiovascular system, including acute-phase reactions, increased hospital admissions, and also an increase in cardiovascular disease mortality in association with elevated particle concentrations. For PM 10 consistent effects were found. Furthermore, the analyses showed that no threshold value could be established, but a linear dose-effect relation. Studies measuring PM 2.5 point to fine particles being mainly responsible for these effects. Current studies show that in addition to fine particles, ultra-fine particles can cause further health effects. (orig.) [de

  20. Long-term neurophysiologic impact of childhood sleep disordered breathing on neurocognitive performance

    Directory of Open Access Journals (Sweden)

    Quan SF

    2013-09-01

    Full Text Available Study Objective. To determine the impact of sleep disordered breathing (SDB in children on neurocognitive function 5 years later.Design, Setting, and Participants. A subgroup of 43 children from the Tucson Children’s Assessment of Sleep Apnea Study (TuCASA who had SDB (RDI > 6 events/hour at their initial exam (ages 6-11 years were matched on the basis of age (within 1 year, gender and ethnicity (Anglo/Hispanic to 43 children without SDB (Control, RDI < 4 events/hour. The Sustained Working Memory Task (SWMT which combines tests of working memory (1-Back Task, reaction time (Simple Reaction Time and attention (Multiplexing Task with concurrent electroencephalographic monitoring was administered approximately 5 years later.Results. There were no differences in performance on the working memory, reaction time and attention tests between the SDB and Control groups. However, the SDB group exhibited lower P300 evoked potential amplitudes during the Simple Reaction Time and Multiplexing Tasks. Additionally, peak alpha power during the Multiplexing Task was lower in the SDB Group with a similar trend in the Simple Reaction Time Task (p=0.08.Conclusions. SDB in children may cause subtle long-term changes in executive function that are not detectable with conventional neurocognitive testing and are only evident during neuroelectrophysiologic monitoring.

  1. Impact of liability and site closure and long-term care issues on future siting efforts

    International Nuclear Information System (INIS)

    Carlin, E.M.; Hana, S.L.A.

    1988-01-01

    Washington's research in the area of financial responsibility for liability and cleanup for radioactive materials licensees and low-level radioactive waste permittees is offered to assist unsited states and regions in their planning and development of new low-level waste disposal capacity. The state considered the need for third party bodily injury and property damage financial responsibility and determined that the USDOT requirements comprehensively cover transport of wastes. In regard to licensees' facilities, it is the state's opinion that an adequate technical basis for third party requirements has not yet been developed. Also considered was the need for financial assurance for cleanup, which is covered for transportation, but generally not available for facilities. Three options are examined to provide such coverage, and the economic impact on licensees assessed. Finally, the current low-level waste disposal site operator's insurance coverage is analyzed and deficiencies are identified. Washington is also conducting research into site closure and perpetual care and maintenance requirements for the commercial low-level radioactive waste disposal facility located on the Hanford reservation near Richland, Washington. This research includes a site assessment and identification and formulation of site-specific design elements for closure and long-term care

  2. Clinical Risk Factors for Head Impact During Falls in Older Adults: A Prospective Cohort Study in Long-Term Care.

    Science.gov (United States)

    Yang, Yijian; Mackey, Dawn C; Liu-Ambrose, Teresa; Leung, Pet-Ming; Feldman, Fabio; Robinovitch, Stephen N

    To examine risk factors associated with head impact during falls in older adults in long-term care (LTC). Two LTC facilities in British Columbia, Canada. 160 LTC residents. Prospective cohort study. Between 2007 and 2014, we video captured 520 falls experienced by participants. Each fall video was analyzed to determine whether impact occurred to the head. Using generalized estimating equation models, we examined how head impact was associated with other fall characteristics and health status prior to the fall. Head impact occurred in 33% of falls. Individuals with mild cognitive impairment were at higher risk for head impact (odds ratio = 2.8; 95% confidence interval, 1.5-5.0) than those with more severe cognitive impairment. Impaired vision was associated with 2.0-fold (1.3-3.0) higher odds of head impact. Women were 2.2 times (1.4-3.3) more likely than men to impact their head during a fall. Head impact is common during falls in LTC, with less cognitively impaired, female residents who suffered from visual impairment, being most likely to impact their head. Future research should focus on improving our ability to detect neural consequences of head impact and evaluating the effect of interventions for reducing the risk for fall-related head injuries in LTC.

  3. REMINDER : Changes in family situation are to be declared promptly

    CERN Multimedia

    HR Department

    2012-01-01

    All changes in the family situation of members of the personnel (employed or associated) have to be declared without delay and in writing to the Organization.   Among the changes that shall be notified within 30 calendar days of their occurrence, the most frequent ones are: • marriage; • divorce; • entering into a partnership officially registered in a Member State; • dissolution of such a partnership; • death of the spouse or partner; and • birth or death of a child. For more information, in particular on how to declare any of the above changes, please see the CERN Admin e-guide. In addition, any change to the health insurance situation, the income or retirement pension of the spouse or partner of any staff member or fellow also has to be declared to the Organization in writing within 30 calendar days of its occurrence. Such changes shall be declared using the EDH “CHIS Declaration of health insurance situation spouse/partner&...

  4. Short-term impacts of a 4-lane highway on black bears in eastern North Carolina

    Science.gov (United States)

    Van Manen, Frank T.; McCollister, Matthew F.; Nicholson, Jeremy M.; Thompson, Laura M.; Kindall, Jason L.; Jones, Mark D.

    2012-01-01

    Among numerous anthropogenic impacts on terrestrial landscapes, expanding transportation networks represent one of the primary challenges to wildlife conservation worldwide. Larger mammals may be particularly vulnerable because of typically low densities, low reproductive rates, and extensive movements. Although numerous studies have been conducted to document impacts of road networks on wildlife, inference has been limited because of experimental design limitations. During the last decade, the North Carolina Department of Transportation (NCDOT) rerouted and upgraded sections of United States Highway 64 between Raleigh and the Outer Banks to a 4-lane, divided highway. A new route was selected for a 24.1-km section in Washington County. The new section of highway included 3 wildlife underpasses with adjacent wildlife fencing to mitigate the effects of the highway on wildlife, particularly American black bears (Ursus americanus). We assessed the short-term impacts of the new highway on spatial ecology, population size, survival, occupancy, and gene flow of black bears. We tested our research hypotheses using a before-after control-impact (BACI) study design. We collected data during 2000–2001 (preconstruction phase) and 2006–2007 (postconstruction phase) in the highway project area and a nearby control area (each approx. 11,000 ha), resulting in 4 groups of data (i.e., pre- or postconstruction study phase, treatment or control area). We captured and radiocollared 57 bears and collected 5,775 hourly locations and 4,998 daily locations. Using mixed-model analysis of variance and logistic regression, we detected no differences in home ranges, movement characteristics, proximity to the highway alignment, or habitat use between the 2 study phases, although minimum detectable effect sizes were large for several tests. However, after completion of the new highway, bears on the treatment area became less inactive in morning, when highway traffic was low, compared with

  5. Impact of Electronic Health Records on Long-Term Care Facilities: Systematic Review.

    Science.gov (United States)

    Kruse, Clemens Scott; Mileski, Michael; Vijaykumar, Alekhya Ganta; Viswanathan, Sneha Vishnampet; Suskandla, Ujwala; Chidambaram, Yazhini

    2017-09-29

    Long-term care (LTC) facilities are an important part of the health care industry, providing care to the fastest-growing group of the population. However, the adoption of electronic health records (EHRs) in LTC facilities lags behind other areas of the health care industry. One of the reasons for the lack of widespread adoption in the United States is that LTC facilities are not eligible for incentives under the Meaningful Use program. Implementation of an EHR system in an LTC facility can potentially enhance the quality of care, provided it is appropriately implemented, used, and maintained. Unfortunately, the lag in adoption of the EHR in LTC creates a paucity of literature on the benefits of EHR implementation in LTC facilities. The objective of this systematic review was to identify the potential benefits of implementing an EHR system in LTC facilities. The study also aims to identify the common conditions and EHR features that received favorable remarks from providers and the discrepancies that needed improvement to build up momentum across LTC settings in adopting this technology. The authors conducted a systematic search of PubMed, Cumulative Index of Nursing and Allied Health (CINAHL), and MEDLINE databases. Papers were analyzed by multiple referees to filter out studies not germane to our research objective. A final sample of 28 papers was selected to be included in the systematic review. Results of this systematic review conclude that EHRs show significant improvement in the management of documentation in LTC facilities and enhanced quality outcomes. Approximately 43% (12/28) of the papers reported a mixed impact of EHRs on the management of documentation, and 33% (9/28) of papers reported positive quality outcomes using EHRs. Surprisingly, very few papers demonstrated an impact on patient satisfaction, physician satisfaction, the length of stay, and productivity using EHRs. Overall, implementation of EHRs has been found to be effective in the few LTC

  6. The long-term environmental impacts of the Mount Polley mine tailings spill, British Columbia, Canada

    Science.gov (United States)

    Byrne, Patrick; Hudson-Edwards, Karen; Macklin, Mark; Brewer, Paul; Bird, Graham; Williams, Richard

    2015-04-01

    On the 4th August 2014 a tailings impoundment failure at the Mount Polley gold and copper mine in British Columbia, Canada, released approximately 25 million m3 of solid and liquid waste into Hazeltine Creek, Quesnel Lake and Polley Lake. The sheer volume of the tailings released caused Haseltine Creek channel to expand from 2m to over 25m in width and Polley Lake water level to rise by 1.7m. The spill also removed trees in a 900 km2 corridor either side of Hazeltine Creek. Local residents and government officials have expressed serious concerns regarding the potential long-term effects on regional biodiversity, water security and to the livelihoods of First Nation communities. Among impoundment failures, the Mount Polley disaster is unique in that the solid tailings contain an unusual mixture of metal contaminants (arsenic, copper, gold, manganese, nickel, lead, vanadium). As particulate matter is the principal carrier of metal contaminants, the spilled tailings may reside in the regional soils and sediments for 1000s of years serving as a secondary source of pollution. The environmental risk posed by the spilled tailings is compounded by the location of the spill in a mountainous forested catchment, affected by severe winters with prominent spring snow melts that have the potential to remobilise very large quantities of spilled tailings. No data currently exist on the short- to long-term behaviour of these tailings in soils and sediments and the effects of the clean-up operations on their behaviour in this type of river environment. In this study, we adopt a multidisciplinary approach to determine the environmental and geomorphological impacts of the tailings spill. We have two specific objectives. (1) The physicochemical speciation and geochemical stability of spilled tailings will be characterised in surface and hyporheic sediments using bulk chemistry, mineralogical (XRD and SEM) and speciation methods (sequential extractions, electron microprobe analysis, XAS

  7. Projecting the long-term biogeochemical impacts of a diverse agroforestry system in the Midwest

    Science.gov (United States)

    Wolz, K. J.; DeLucia, E. H.; Paul, R. F.

    2014-12-01

    results illustrate the potential long-term biogeochemical impacts that can be generated by a land-use transition to a diverse agroforestry system in the Midwest.

  8. Impact of changing the Japanese term for "schizophrenia" for reasons of stereotypical beliefs of schizophrenia in Japanese youth.

    Science.gov (United States)

    Takahashi, Hidehiko; Ideno, Takashi; Okubo, Shigetaka; Matsui, Hiroshi; Takemura, Kazuhisa; Matsuura, Masato; Kato, Motoichiro; Okubo, Yoshiro

    2009-07-01

    The old term for schizophrenia, "Seishin-Bunretsu-Byo" (Mind-Split Disease), has been replaced by "Togo-Shitcho-Sho" (Integration Disorder) in Japan. Stigma research requiring individuals to report personal beliefs is useful but is subject to social desirability bias. Using the Implicit Association Test, a measurement designed to minimize this bias, we assessed the impact of this renaming on the stereotype of schizophrenia held by a younger generation. The old term was strongly associated with "criminal", and this association became significantly weaker with the new term. The strategy of renaming holds considerable promise for tempering negative bias toward this disorder in Japan.

  9. Disclosure rules and declared essential patents

    NARCIS (Netherlands)

    Bekkers, R.N.A.; Catalini, C.; Martinelli, Arianna; Righi, C.; Simcoe, T.

    Many standard setting organizations (SSOs) require participants to disclose patents that might be infringed by implementing a proposed standard, and commit to license their “essential” patents on terms that are at least fair, reasonable and non-discriminatory (FRAND). Data from these SSO

  10. Declarative memory in abused and neglected infants.

    Science.gov (United States)

    Cheatham, Carol L; Larkina, Marina; Bauer, Patricia J; Toth, Sheree L; Cicchetti, Dante

    2010-01-01

    's imitative behaviors. Thus, it would appear that maternal negative feedback to child-initiated behaviors is related to an increase in imitative behaviors that are most likely met with positive reinforcement. The continued pursuit of this positivity may impede the development of self-initiated behaviors; delayed development of self-initiated behavior has been linked to disorders of social competence (Landry, Smith, Miller-Loncar, & Swank, 1998). However, imitation has long been known to be a mechanism of learning (Piaget, 1962) and has become an accepted tool for assessment of declarative memory (Bauer, 2004). Whereas the adaptation to abuse posited by Valentino et al. (2006) may be detrimental to social development, our data for this same sample indicate that the reliance on imitative behavior exhibited by the abused children may afford them an advantage at 21 months of age in imitation paradigms. The neglected children are thus at a disadvantage relative to the abused children in the study reported here in that they were not reinforced by mothers for imitative behavior. It is important to note that all children in this sample were from low-income homes. Scores on these events for both target actions and ordered pairs are higher in samples of higher SES children (e.g., Bauer et al., 2000). Thus, the low SES of the families affected performance across the groups. It is possible that the factor responsible for the difference between the abused group and the neglected group is resilience in the face of poverty. Resilience is the ability to recover following a traumatic event or adversity (Masten, 2001), and has been related to child characteristics, such as general intelligence (Masten et al., 1988). It has been proposed that neural plasticity may be responsible for this recovery (Cicchetti & Curtis, 2006). Alternatively, as has been detailed earlier in this chapter, the advantage afforded abused children could arise from the strengthening of neural pathways. It would be

  11. Long-term health and medical cost impact of smoking prevention in adolescence.

    Science.gov (United States)

    Wang, Li Yan; Michael, Shannon L

    2015-02-01

    To estimate smoking progression probabilities from adolescence to young adulthood and to estimate long-term health and medical cost impacts of preventing smoking in today's adolescents. Using data from the National Longitudinal Study of Adolescent Health (Add Health), we first estimated smoking progression probabilities from adolescence to young adulthood. Then, using the predicted probabilities, we estimated the number of adolescents who were prevented from becoming adult daily smokers as a result of a hypothetical 1 percentage point reduction in the prevalence of ever smoking in today's adolescents. We further estimated lifetime medical costs saved and quality-adjusted life years (QALYs) gained as a result of preventing adolescents from becoming adult daily smokers. All costs were in 2010 dollars. Compared with never smokers, those who had tried smoking at baseline had higher probabilities of becoming current or former daily smokers at follow-up regardless of baseline grade or sex. A hypothetical 1 percentage point reduction in the prevalence of ever smoking in 24.5 million students in 7th-12th grades today could prevent 35,962 individuals from becoming a former daily smoker and 44,318 individuals from becoming a current daily smoker at ages 24-32 years. As a result, lifetime medical care costs are estimated to decrease by $1.2 billion and lifetime QALYs is estimated to increase by 98,590. Effective smoking prevention programs for adolescents go beyond reducing smoking prevalence in adolescence; they also reduce daily smokers in young adulthood, increase QALYs, and reduce medical costs substantially in later life. This finding indicates the importance of continued investment in effective youth smoking prevention programs. Published by Elsevier Inc.

  12. Measuring Long-Term Impact Based on Network Centrality: Unraveling Cinematic Citations

    Science.gov (United States)

    Spitz, Andreas; Horvát, Emőke-Ágnes

    2014-01-01

    Traditional measures of success for film, such as box-office revenue and critical acclaim, lack the ability to quantify long-lasting impact and depend on factors that are largely external to the craft itself. With the growing number of films that are being created and large-scale data becoming available through crowd-sourced online platforms, an endogenous measure of success that is not reliant on manual appraisal is of increasing importance. In this article we propose such a ranking method based on a combination of centrality indices. We apply the method to a network that contains several types of citations between more than 40,000 international feature films. From this network we derive a list of milestone films, which can be considered to constitute the foundations of cinema. In a comparison to various existing lists of ‘greatest’ films, such as personal favourite lists, voting lists, lists of individual experts, and lists deduced from expert polls, the selection of milestone films is more diverse in terms of genres, actors, and main creators. Our results shed light on the potential of a systematic quantitative investigation based on cinematic influences in identifying the most inspiring creations in world cinema. In a broader perspective, we introduce a novel research question to large-scale citation analysis, one of the most intriguing topics that have been at the forefront of scientific enquiries for the past fifty years and have led to the development of various network analytic methods. In doing so, we transfer widely studied approaches from citation analysis to the the newly emerging field of quantification efforts in the arts. The specific contribution of this paper consists in modelling the multidimensional cinematic references as a growing multiplex network and in developing a methodology for the identification of central films in this network. PMID:25295877

  13. Long-term weight gain and economic impact in pigs castrated under local anaesthesia

    Directory of Open Access Journals (Sweden)

    F.G. Telles

    2016-12-01

    Full Text Available Castration is a controversial practice in swine production because in some countries is still performed without anaesthesia, and therefore causes intense suffering and stress to animals. This study investigated the effect of pre-surgical administration of local anaesthesia (LA on the growth performance of piglets until the end of the growth phase (102 days. Piglets aged 3 to 5 days were selected in pairs of similar weights and same age. They were originated from 22 litters. The groups were randomly assigned to one of two treatments. Castration was performed with (LA; n = 45 or without (NLA; n = 45 intra-testicular administration of 0.5 mL of 2% lidocaine plus adrenaline per testicle, administered by an automatic repeating vaccinator. Castration was performed 10 min later. Average daily weight gain and economic impact were evaluated between the intervals before castration until 21 (weaning phase, before castration until 60 (end of the initial nursery phase and before castration until 102 (growth phase days of age. Average daily weight gain data were analyzed by comparing the average daily weight gain between the weaning phase, 60 and 102 days of age versus the initial weight (pre-castration. At the end of the growing phase, animals treated with LA showed greater weight gain than animals castrated without anaesthesia. LA also showed improved cost:benefit ratio and theore might provide greater economic benefit under the conditions used in this study. Our findings have proved that castration with LA improves long-term weight gain of piglets.

  14. Impact of iron chelators on short-term dissolution of basaltic glass

    Science.gov (United States)

    Perez, Anne; Rossano, Stéphanie; Trcera, Nicolas; Verney-Carron, Aurélie; Huguenot, David; van Hullebusch, Eric D.; Catillon, Gilles; Razafitianamaharavo, Angelina; Guyot, François

    2015-08-01

    Although microorganisms seem to play an important role in the alteration processes of basaltic glasses in solution, the elementary mechanisms involved remain unclear in particular with regard to the role of organic ligands excreted by the cells. Two glasses, one with Fe and one without Fe were synthesized to model basaltic glass compositions. Fe in the glass was mostly Fe(III) for enhancing interaction with siderophores, yet with small but significant amounts of Fe(II) (between 10% and 30% of iron). The prepared samples were submitted to abiotic alteration experiments in buffered (pH 6.4) diluted solutions of metal-specific ligands, namely oxalic acid (OA, 10 mM), desferrioxamine (DFA, 1 mM) or 2,2‧-bipyridyl (BPI, 1 mM). Element release from the glass into the solution after short term alteration (maximum 1 week) was measured by ICP-OES, and normalized mass losses and relative release ratios (with respect to Si) were evaluated for each element in each experimental condition. The presence of organic ligands had a significant effect on the dissolution of both glasses. Trivalent metals chelators (OA, DFA) impacted on the release of Fe3+ and Al3+, and thus on the global dissolution of both glasses, enhancing all release rates and dissolution stoichiometry (release rates were increased up to 7 times for Al or Fe). As expected, the mostly divalent metal chelator BPI interacted preferentially with Ca2+, Mg2+ and Fe2+. This study thus allows to highlight the central roles of iron and aluminium in interaction with some organic ligands in the alteration processes of basaltic glasses. It thus provides a step toward understanding the biological contribution of this fundamental geological process.

  15. Prevalence of Jones Fracture Repair and Impact on Short-Term NFL Participation.

    Science.gov (United States)

    Tu, Leigh-Anne; Knapik, Derrick M; Sheehan, Joseph; Salata, Michael J; Voos, James E

    2018-01-01

    Elite American football athletes are at high risk for Jones fractures. Fixation is recommended to minimize nonunion and allow early return to play. The purpose of this investigation was to evaluate the prevalence of Jones fracture repair in athletes invited to the National Football League (NFL) Combine and the impact of fracture repair on short-term NFL participation compared to athletes with no history of repair. A total of 1311 athletes participating in the Combine from 2012 to 2015 were evaluated. Athletes with history of Jones fracture repair were identified. Athlete demographic information was collected while physical examination findings were recorded. Radiographs were evaluated to determine fixation type and the presence of nonunion. Future participation in the NFL was evaluated based on draft status, games played, and games started in the athlete's first season following the Combine. Fixation was performed for 41 Jones fractures in 40 athletes (3.1%). The highest prevalence was in defensive linemen (n = 10 athletes), with the greatest rate in tight ends (5.1%, n = 4 of 79 athletes). Intramedullary screw fixation was used for all fractures. Incomplete bony union was present in 3 (8%) fractures. Athletes with a history of repair were not at significant risk for going undrafted ( P = .61), playing ( P = .23), or starting ( P = .76) fewer NFL games compared to athletes with no history of repair during athletes' first NFL season. Athletes with a history of Jones fracture repair were not at significant risk of going undrafted or for diminished participation during their first season in the NFL. Level IV, case series.

  16. Measuring long-term impact based on network centrality: unraveling cinematic citations.

    Directory of Open Access Journals (Sweden)

    Andreas Spitz

    Full Text Available Traditional measures of success for film, such as box-office revenue and critical acclaim, lack the ability to quantify long-lasting impact and depend on factors that are largely external to the craft itself. With the growing number of films that are being created and large-scale data becoming available through crowd-sourced online platforms, an endogenous measure of success that is not reliant on manual appraisal is of increasing importance. In this article we propose such a ranking method based on a combination of centrality indices. We apply the method to a network that contains several types of citations between more than 40,000 international feature films. From this network we derive a list of milestone films, which can be considered to constitute the foundations of cinema. In a comparison to various existing lists of 'greatest' films, such as personal favourite lists, voting lists, lists of individual experts, and lists deduced from expert polls, the selection of milestone films is more diverse in terms of genres, actors, and main creators. Our results shed light on the potential of a systematic quantitative investigation based on cinematic influences in identifying the most inspiring creations in world cinema. In a broader perspective, we introduce a novel research question to large-scale citation analysis, one of the most intriguing topics that have been at the forefront of scientific enquiries for the past fifty years and have led to the development of various network analytic methods. In doing so, we transfer widely studied approaches from citation analysis to the the newly emerging field of quantification efforts in the arts. The specific contribution of this paper consists in modelling the multidimensional cinematic references as a growing multiplex network and in developing a methodology for the identification of central films in this network.

  17. Assessing the impact of agricultural R&D investments on long-term projections of food security

    NARCIS (Netherlands)

    Kristkova, Zuzana Smeets; Dijk, Van Michiel; Meijl, Van Hans

    2017-01-01

    The purpose of this chapter is to analyze the impact of public agricultural Research and Development (R&D) investments on agricultural productivity and long-term food security to derive policy recommendations. The methodological approach is based on the application of the state-of-the art

  18. The Long-Term Impact of Admission Policies: A Comparative Study of Two Emergent Research Institutions in Texas

    Science.gov (United States)

    Crisp, Gloria; Horn, Catherine; Dizinno, Gerry; Barlow, Libby

    2013-01-01

    The present study explored the long-term impact of admission policies at two aspiring research institutions in Texas. Six years of longitudinal institutional data were analyzed for all full-time first time in college undergraduate students at both universities. Descriptive and inferential statistics were used to identify relationships and…

  19. Assessing the Long-term Impact of Microcredit on Rural Poverty: Does the Timing and Length of Participation Matter?

    NARCIS (Netherlands)

    Berhane, G.; Gardebroek, C.

    2012-01-01

    In recent years, microfinance institutions are seen as beacons of hope to help eradicate poverty through, among others, providing credit to poor rural households. Availability of small but repeated loans is, in the long-term, expected to impact on poverty. However, decades after the introduction of

  20. Impacts of long-term waste-water irrigation on the development of sandy Luvisols: consequences for metal pollutant distributions

    NARCIS (Netherlands)

    Oort, van F.; Jongmans, A.G.; Lamy, I.; Baize, D.; Chevallier, P.

    2008-01-01

    Studies relating macro- and microscopic aspects of impacts of long-term contaminative practices on soils are scarce. We performed such an approach by assessing the fate of metal pollutants in an area close to Paris, where sandy Luvisols were irrigated for 100 years with urban waste water. As a

  1. Evaluating Indicator-Based Methods of "Measuring Long-Term Impacts of a Science Center on Its Community"

    Science.gov (United States)

    Jensen, Eric Allen

    2016-01-01

    This article addresses some of the challenges faced when attempting to evaluate the long-term impact of informal science learning interventions. To contribute to the methodological development of informal science learning research, we critically examine (Falk and Needham (2011) "Journal of Research in Science Teaching," 48: 1-12.) study…

  2. Impact of Infection Prevention and Control Initiatives on Acute Respiratory Infections in a Pediatric Long-Term Care Facility.

    Science.gov (United States)

    Murray, Meghan T; Jackson, Olivia; Cohen, Bevin; Hutcheon, Gordon; Saiman, Lisa; Larson, Elaine; Neu, Natalie

    2016-07-01

    We evaluated the collective impact of several infection prevention and control initiatives aimed at reducing acute respiratory infections (ARIs) in a pediatric long-term care facility. ARIs did not decrease overall, though the proportion of infections associated with outbreaks and average number of cases per outbreak decreased. Influenza rates decreased significantly. Infect Control Hosp Epidemiol 2016;37:859-862.

  3. Safety case methodology for decommissioning of research reactors. Assessment of the long term impact of a flooding scenario

    International Nuclear Information System (INIS)

    Vladescu, G.; Banciu, O.

    1999-01-01

    The paper contains the assessment methodology of a Safety Case fuel decommissioning of research reactors, taking into account the international approach principles. The paper also includes the assessment of a flooding scenario for a decommissioned research reactor (stage 1 of decommissioning). The scenario presents the flooding of reactor basement, radionuclide migration through environment and long term radiological impact for public. (authors)

  4. Long-term socio-economic impact of vestibular schwannoma for patients under observation and after surgery

    DEFF Research Database (Denmark)

    Tos, Tina; Caye-Thomasen, Per; Stangerup, Sven-Eric

    2003-01-01

    This study describes and compares the long-term socio-economic impact for patients diagnosed with a vestibular schwannoma and either operated on or observed. A consecutive sample of patients diagnosed with vestibular schwannoma in Denmark and either operated on (748 patients) or observed...

  5. Memory for semantically related and unrelated declarative information: the benefit of sleep, the cost of wake.

    Directory of Open Access Journals (Sweden)

    Jessica D Payne

    Full Text Available Numerous studies have examined sleep's influence on a range of hippocampus-dependent declarative memory tasks, from text learning to spatial navigation. In this study, we examined the impact of sleep, wake, and time-of-day influences on the processing of declarative information with strong semantic links (semantically related word pairs and information requiring the formation of novel associations (unrelated word pairs. Participants encoded a set of related or unrelated word pairs at either 9 am or 9 pm, and were then tested after an interval of 30 min, 12 hr, or 24 hr. The time of day at which subjects were trained had no effect on training performance or initial memory of either word pair type. At 12 hr retest, memory overall was superior following a night of sleep compared to a day of wakefulness. However, this performance difference was a result of a pronounced deterioration in memory for unrelated word pairs across wake; there was no sleep-wake difference for related word pairs. At 24 hr retest, with all subjects having received both a full night of sleep and a full day of wakefulness, we found that memory was superior when sleep occurred shortly after learning rather than following a full day of wakefulness. Lastly, we present evidence that the rate of deterioration across wakefulness was significantly diminished when a night of sleep preceded the wake period compared to when no sleep preceded wake, suggesting that sleep served to stabilize the memories against the deleterious effects of subsequent wakefulness. Overall, our results demonstrate that 1 the impact of 12 hr of waking interference on memory retention is strongly determined by word-pair type, 2 sleep is most beneficial to memory 24 hr later if it occurs shortly after learning, and 3 sleep does in fact stabilize declarative memories, diminishing the negative impact of subsequent wakefulness.

  6. New procedure for declaring changes in family and personal situation

    CERN Multimedia

    2014-01-01

    On taking up their appointment, Members of the Personnel (employed and associated) are required to provide official documents as evidence of their family situation. Any subsequent change in their personal situation, or that of their family members, must be declared in writing to the Organization within 30 calendar days.   As part of their efforts to simplify procedures, the Administrative Processes Section (DG-RPC-PA) and the HR and GS Departments have produced a new EDH form entitled “Change of family and personal situation", which must be used to declare the following changes: birth or adoption of a child; marriage; divorce; entry into a civil partnership officially registered in a Member State; dissolution of such a partnership; change of name; change of nationality or new nationality.   Members of the Personnel must create the form themselves and provide the information required for the type of declaration concerned, indicating, if applicable, any benefit...

  7. A compensatory role for declarative memory in neurodevelopmental disorders

    Science.gov (United States)

    Ullman, Michael T.; Pullman, Mariel Y.

    2015-01-01

    Most research on neurodevelopmental disorders has focused on their abnormalities. However, what remains intact may also be important. Increasing evidence suggests that declarative memory, a critical learning and memory system in the brain, remains largely functional in a number of neurodevelopmental disorders. Because declarative memory remains functional, and because this system can learn and retain numerous types of information, functions, and tasks, it should be able to play compensatory roles for multiple types of impairments across the disorders. Here, we examine this hypothesis for specific language impairment, dyslexia, autism spectrum disorder, Tourette syndrome, and obsessive-compulsive disorder. We lay out specific predictions for the hypothesis and review existing behavioral, electrophysiological, and neuroimaging evidence. Overall, the evidence suggests that declarative memory indeed plays compensatory roles for a range of impairments across all five disorders. Finally, we discuss diagnostic, therapeutic and other implications. PMID:25597655

  8. Not to declare dead someone still alive: Case reports

    Directory of Open Access Journals (Sweden)

    Anđelić Slađana

    2015-01-01

    Full Text Available Introduction. Diagnosing death represents an activity that carries a great deal of public responsibility for medical professionals and is continually exposed to the control of citizens and media. Although this is a taboo subject in medical circles, unfortunately in medical practice there are situations when the physician issues a death diagnosis form without even examining the person or for an already buried person. Such physician’s action is impermissible and it leads to the possibility of professional and criminal law punishment. Case Outline. By giving examples from practice, we wish to point out the need for exceptional caution when confirming and diagnosing death in order to diagnose the true, i.e. rule out apparent death and consequently avoid the mistake of declaring dead someone still alive. Conclusion. When confirming and declaring death, exceptional caution of the physician is necessary so as not to declare dead someone still alive!

  9. Impact of short-term hemodialysis catheters on the central veins: a catheter venographic study

    Energy Technology Data Exchange (ETDEWEB)

    Oguzkurt, Levent E-mail: loguzkurt@yahoo.com; Tercan, Fahri; Torun, Dilek; Yildirim, Tuelin; Zuemruetdal, Ayseguel; Kizilkilic, Osman

    2004-12-01

    Objective: To determine the incidence of pericatheter sleeve formation, thrombus formation, and stenosis of the central veins in hemodialysis patients with temporary catheters. Methods and material: In this prospective study, 57 patients (40 males, 17 females) with temporary dialysis catheters had catheter venography by pulling back the catheter just before removal. Patient's age range was 25-87 years (mean age, 51 years). The venographic studies were evaluated for pericatheter sleeve formation, thrombus formation, and stenosis of the brachiocephalic vein (BCV) and the superior vena cava (SVC). The IJV could only be evaluated if there was adequate filling during contrast administration. In a subgroup of patients who had had only right IJV or only right SCV catheters, impact of these catheters on the central veins was compared. Results: The catheter location was right internal jugular vein (IJV) in 26 cases, right subclavian vein (SCV) in 27 cases, left IJV in 1 case, and left SCV in 3 cases. Thirty-two patients (56%) had had only one temporary catheter and the rest had had more than one inserted. The mean dwell time for the catheters was 21 days (range 7-59 days). A pericatheter sleeve was detected on venography in 32 (56%) patients and thrombus formation was noted in 16 patients (28%). A total of 41 patients (72%) exhibited pericatheter sleeve and/or thrombus formation. While 19 of the 32 patients (59%) without previous catheterization had a sleeve around the catheter, only 13 (52%) of 25 patients who had had multiple catheters inserted had a sleeve (P>0.05). Of the eight patients (14%) with BCV stenosis, two had >50% stenosis. Only one patient (2%) had mild stenosis of the SVC. Three patients out of 15 (20%) who had diagnostic venography for the IJV had severe stenosis of the vein. Pericatheter sleeve formation was more frequent in women (P<0.05). However, there were no statistical differences with respect to pericatheter sleeve formation, luminal filling

  10. Impacts of high energy prices on long-term energy-economic scenarios for Germany

    Energy Technology Data Exchange (ETDEWEB)

    Krey, V.; Markewitz, P. [Research Center Juelich, Inst. of Energy Res., Systems Analysis and Technology Evaluation, Juelich (Germany); Horn, M. [DIW Berlin, Berlin (Germany); Matthes, C.; Graichen, V.; Harthan, R.O.; Repenning, J. [Oeko-Institut, Berlin (Germany)

    2007-05-15

    Prices of oil and other fossil fuels on global markets have reached a high level in recent years. These levels were not able to be reproduced on the basis of scenarios and prognoses that were published in the past. New scenarios, based on higher energy price trajectories, have appeared only recently. The future role of various energy carriers and technologies in energy-economic scenarios will greatly depend on the level of energy prices. Therefore, an analysis of the impact of high energy prices on long-term scenarios for Germany was undertaken. Based on a reference scenario with moderate prices, a series of consistent high price scenarios for primary and secondary energy carriers were developed. Two scenarios with (i) continuously rising price trajectories and (ii) a price shock with a price peak during the period 2010-15 and a subsequent decline to the reference level are analysed. Two types of models have been applied in the analysis. The IKARUS energy systems optimisation model covers the whole of the German energy system from primary energy supply down to the end-use sectors. Key results in both high price scenarios include a replacement of natural gas by hard coal and renewable energy sources in electricity and heat generation. Backstop technologies like coal liquefaction begin to play a role under such conditions. Up to 10% of final energy consumption is saved in the end-use sectors, with the residential and transport sector being the greatest contributors. Even without additional restrictions, CO{sub 2} emissions significantly drop in comparison to the reference scenario. The ELIAS electricity investment analysis model focuses on the power sector. In the reference scenario with current allocation rules in the emissions trading scheme, the CO{sub 2} emissions decrease relatively steadily. The development is characterised by the phaseout of nuclear energy which is counterweighted by the increase of renewable. In the high price scenario, the CO{sub 2

  11. Sand mining impacts on long-term dune erosion in southern Monterey Bay

    Science.gov (United States)

    Thornton, E.B.; Sallenger, Abby; Sesto, Juan Conforto; Egley, L.; McGee, Timothy; Parsons, Rost

    2006-01-01

    Southern Monterey Bay was the most intensively mined shoreline (with sand removed directly from the surf zone) in the U.S. during the period from 1906 until 1990, when the mines were closed following hypotheses that the mining caused coastal erosion. It is estimated that the yearly averaged amount of mined sand between 1940 and 1984 was 128,000 m3/yr, which is approximately 50% of the yearly average dune volume loss during this period. To assess the impact of sand mining, erosion rates along an 18 km range of shoreline during the times of intensive sand mining (1940–1990) are compared with the rates after sand mining ceased (1990–2004). Most of the shoreline is composed of unconsolidated sand with extensive sand dunes rising up to a height of 46 m, vulnerable to the erosive forces of storm waves. Erosion is defined here as a recession of the top edge of the dune. Recession was determined using stereo-photogrammetry, and LIDAR and GPS surveys. Long-term erosion rates vary from about 0.5 m/yr at Monterey to 1.5 m/yr in the middle of the range, and then decrease northward. Erosion events are episodic and occur when storm waves and high tides coincide, allowing swash to undercut the dune and resulting in permanent recession. Erosion appears to be correlated with the occurrence of El Niños. The calculated volume loss of the dune in southern Monterey Bay during the 1997–98 El Niño winter was 1,820,000 m3, which is almost seven times the historical annual mean dune erosion of 270,000 m3/yr. The alongshore variation in recession rates appears to be a function of the alongshore gradient in mean wave energy and depletions by sand mining. After cessation of sand mining in 1990, the erosion rates decreased at locations in the southern end of the bay but have not significantly changed at other locations.

  12. Short/Medium-Term Macroeconomic Impact of Investment Associated with 'Grenelle de l'Environnement' Investments on Growth and Employment

    International Nuclear Information System (INIS)

    Guillerminet, Marie-Laure; Briard, Philippe; Fery, Pierre; Galko, Elodie; Klein, Caroline; Ollivier, Timothee

    2016-01-01

    The 'Grenelle de l'Environnement' is a French policy aimed at achieving the objectives defined in the EU climate and energy package. This study evaluates the short- to medium-term impact of the main economic measures of 'Grenelle' on employment and growth. The simulations run with the macro-econometric model Mesange show a positive impact of these measures on GDP and employment in the short run, mainly via the investment multiplier. The impact turns negative from 2020 on because investment slows and taxes increase to finance the latter. These results are robust to different assumptions on oil prices, household saving behaviour, public funding, and productivity gains associated with new transport projects. However, they do not factor in the impact of 'Grenelle' on the environment, competitiveness, and well-being

  13. Working While Studying: The Impact of Term-Time Employment on Dropout Rates

    Science.gov (United States)

    Hovdhaugen, Elisabeth

    2015-01-01

    There are many possible reasons why students leave university prior to degree completion, and one of the more commonly cited is being employed while studying. This paper analyses the impact of employment status on dropout rates using survival analysis. It finds that employment status does have an impact on dropout rates; students who work full…

  14. Dealing with the death of a long term patient; what is the impact and how do podiatrists cope?

    Science.gov (United States)

    Robson, Kristy; Williams, Cylie M

    2017-01-01

    It is common for podiatrists and patients to develop long term professional relationships. Patient's decline in health or death may impact a practitioner's mental wellbeing. This research aimed to understand the impact of long term patient death on podiatrists and identify coping strategies. Australian podiatrists were eligible to participate if they had been practicing longer than 5 years and experienced the death of a long term patient in the previous 12 months. Individual semi-structured interviews were conducted with podiatrists and were audio-recorded, transcribed verbatim and individually analysed to identify key themes. Interpretative phenomenological analysis was used to explore the perceptions of podiatrists on the personal and professional impact following the death of a long term patient. Fifteen podiatrists (11 female) with a median of 15 (range 8-50) years' experience participated. Three major themes emerged: acknowledging connections, willing to share and listen, and creating support through starting the conversation. Participants indicated importance in recognition of the emotional influence of professional-patient relationships. They also discussed the importance of debriefing about death with the right person, which was most commonly colleagues. Participants talked about the emotional impact of death, suggesting the need for supporting discussion and resources, especially for new graduates. Death and dying can be an emotive topic and one which podiatrists may not be prepared for, yet likely to have to deal with throughout their career. These findings enable a better understanding of the impact of patient death and provide possible future directions for the profession to better support podiatrists in this area.

  15. 21 CFR 1313.13 - Contents of import declaration.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Contents of import declaration. 1313.13 Section 1313.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE IMPORTATION AND... was amended by adding paragraph (d), effective May 4, 2010. For the convenience of the user, the added...

  16. Toronto 2001 Inter-governmental Declaration on Clean Air

    International Nuclear Information System (INIS)

    2001-01-01

    This formal declaration commits the municipalities in the Greater Toronto Area, the provincial government of Ontario, and the federal government in Ottawa to undertake certain specific actions to improve air quality in their respective areas of jurisdiction, recognizing the validity of claims made by experts in numerous studies, linking air pollution to premature deaths, illnesses and hospitalization in major Canadian cities. The declaration also recognizes the validity of scientific claims as to the relationship between solar radiation, ambient heat, ground level ozone and global climate change, and the role played in air pollution by fossil fuel combustion. The Declaration calls for cooperation of all governments operating in the Greater Toronto Area to take inter-governmental actions to improve air quality by following up on key issues identified at annual Summits and by supporting the planning of future Summits, by working together with the Toronto Organizing Committee for the Olympic Games to ensure that the 2008 Olympic Games will contribute to a legacy of clean air for the Toronto region, and by implementing a social marketing campaign to help householders reduce both home energy use and vehicle kilometres travelled by 20 per cent. Beyond these inter-governmental commitments, special commitments of individual municipalities, and the provincial and federal governments also form part of the Declaration

  17. Declaration of Basic Principles for the Treatment of Prisoners.

    Science.gov (United States)

    Cosman, J. W.

    1989-01-01

    Education does not flourish in prisons because of prevailing notions about the punitive and retributive purposes of prisons. The United Nations is considering a Declaration of Basic Principles for the Treatment of Prisoners that is intended to bring education to the forefront of criminal justice policy. (SK)

  18. Methylphenidate significantly improves declarative memory functioning of adults with ADHD.

    NARCIS (Netherlands)

    Verster, J.C.; Bekker, E.M.; Kooij, J.J.; Buitelaar, J.K.; Verbaten, M.N.; Volkerts, E.R.; Olivier, B.

    2010-01-01

    BACKGROUND: Declarative memory deficits are common in untreated adults with attention-deficit hyperactivity disorder (ADHD), but limited evidence exists to support improvement after treatment with methylphenidate. The objective of this study was to examine the effects of methylphenidate on memory

  19. 9 CFR 93.521 - Declaration for swine.

    Science.gov (United States)

    2010-01-01

    ... CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND CERTAIN ANIMAL, BIRD, AND POULTRY PRODUCTS; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Swine Mexico 9 § 93.521 Declaration for swine. For all swine offered for importation from Mexico, the importer or his or her agent shall present two copies of...

  20. 9 CFR 93.425 - Declaration for ruminants.

    Science.gov (United States)

    2010-01-01

    ... CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND CERTAIN ANIMAL, BIRD, AND POULTRY PRODUCTS; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Ruminants Mexico 10 § 93.425 Declaration for ruminants. For all ruminants offered for importation from Mexico, the importer or his or her agent shall present...

  1. 9 CFR 93.322 - Declaration for horses.

    Science.gov (United States)

    2010-01-01

    ... CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND CERTAIN ANIMAL, BIRD, AND POULTRY PRODUCTS; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses Mexico 18 § 93.322 Declaration for horses. For all horses offered for importation from Mexico, the importer or his or her agent shall present two...

  2. 9 CFR 93.219 - Declaration for poultry.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Declaration for poultry. 93.219... AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND CERTAIN ANIMAL, BIRD, AND POULTRY PRODUCTS; REQUIREMENTS...

  3. Declaration of the Government of Argentina regime for sensitive exports

    International Nuclear Information System (INIS)

    1992-05-01

    The document reproduces the Declaration of the Government of Argentina concerning the new regime for foreign sales of any materials, equipment, technology, technical assistance and services relating to nuclear or missile technology, and of chemical substances which might be used in the production and deployment of missiles and nuclear, chemical and bacteriological weapons

  4. Uncommon Territory: Declaration, and the Supervision of Queer Design Theses

    Science.gov (United States)

    Ings, Welby John

    2014-01-01

    While attempting to develop authentic, practice-led inquiries into identity, queer students face unique issues. They often need to consider questions of community and frequently find themselves with one foot outside of the academic environment. Many also have to carefully consider the implications of declaration, and the management of trust. This…

  5. Declarative versus imperative process modeling languages : the issue of maintainability

    NARCIS (Netherlands)

    Fahland, D.; Mendling, J.; Reijers, H.A.; Weber, B.; Weidlich, M.; Zugal, S.; Rinderle-Ma, S.; Sadiq, S.; Leymann, F.

    2010-01-01

    The rise of interest in declarative languages for process modeling both justifies and demands empirical investigations into their presumed advantages over more traditional, imperative alternatives. Our concern in this paper is with the ease of maintaining business process models, for example due to

  6. Argentine-Brazilian declaration on common nuclear policy

    International Nuclear Information System (INIS)

    1990-12-01

    The document reproduces the text of the Argentine-Brazilian Declaration on Common Nuclear Policy, signed by the Presidents of Argentina and Brazil at Foz do Ignacu, Brazil, on 28 November 1990. At the invitation of the Governments of Argentina and Brazil, the Agency's Director General attended the signing ceremony

  7. Declarative Joint Attention as a Foundation of Theory of Mind

    Science.gov (United States)

    Sodian, Beate; Kristen-Antonow, Susanne

    2015-01-01

    Theories of social-cognitive development have attributed a foundational role to declarative joint attention. The present longitudinal study of 83 children, who were assessed on a battery of social-cognitive tasks at multiple measurement points from the age of 12 to 50 months, tested a predictive model of theory of mind (false-belief…

  8. Proving termination of logic programs with delay declarations

    NARCIS (Netherlands)

    E. Marchiori; F. Teusink (Frank)

    1996-01-01

    textabstractIn this paper we propose a method for proving termination of logic programs with delay declarations. The method is based on the notion of recurrent logic program, which is used to prove programs terminating wrt an arbitrary selection rule. Most importantly, we use the notion of bound

  9. Learning History through the Universal Declaration of Human Rights

    Science.gov (United States)

    Landorf, Hilary; Pineda, Martha Fernanda

    2007-01-01

    Although adolescent students often do not have knowledge of specific laws, they usually have a keen sense of justice and fairness. In this article, the author discusses the Universal Declaration of Human Rights (UDHR) as a powerful tool to channel students' sense of fairness into visible actions. Adopted in December 1948 by the General Assembly of…

  10. MOCQL: A Declarative Language for Ad-Hoc Model Querying

    DEFF Research Database (Denmark)

    Störrle, Harald

    2013-01-01

    Language (MOCQL), an experimental declarative textual language to express queries (and constraints) on models. We introduce MOCQL by examples and its grammar, evaluate its usability by means of controlled experiments, and find that modelers perform better and experience less cognitive load when working...

  11. Hippocampal declarative memory supports gesture production: Evidence from amnesia.

    Science.gov (United States)

    Hilverman, Caitlin; Cook, Susan Wagner; Duff, Melissa C

    2016-12-01

    Spontaneous co-speech hand gestures provide a visuospatial representation of what is being communicated in spoken language. Although it is clear that gestures emerge from representations in memory for what is being communicated (De Ruiter, 1998; Wesp, Hesse, Keutmann, & Wheaton, 2001), the mechanism supporting the relationship between gesture and memory is unknown. Current theories of gesture production posit that action - supported by motor areas of the brain - is key in determining whether gestures are produced. We propose that when and how gestures are produced is determined in part by hippocampally-mediated declarative memory. We examined the speech and gesture of healthy older adults and of memory-impaired patients with hippocampal amnesia during four discourse tasks that required accessing episodes and information from the remote past. Consistent with previous reports of impoverished spoken language in patients with hippocampal amnesia, we predicted that these patients, who have difficulty generating multifaceted declarative memory representations, may in turn have impoverished gesture production. We found that patients gestured less overall relative to healthy comparison participants, and that this was particularly evident in tasks that may rely more heavily on declarative memory. Thus, gestures do not just emerge from the motor representation activated for speaking, but are also sensitive to the representation available in hippocampal declarative memory, suggesting a direct link between memory and gesture production. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Alma-0: an imperative language that supports declarative programming

    NARCIS (Netherlands)

    K.R. Apt (Krzysztof); J. Brunekreef; V. Partinton; A. Schaerf

    1997-01-01

    textabstractWe describe here an implemented small programming language, called Alma, that augments the expressive power of imperative programming by a limited number of features inspired by the logic programming paradigm. These additions encourage declarative programming and make it a more

  13. 9 CFR 93.804 - Declaration upon arrival.

    Science.gov (United States)

    2010-01-01

    ... FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Elephants, Hippopotami, Rhinoceroses, and Tapirs § 93.804 Declaration upon arrival. Upon arrival of an elephant, hippopotamus, rhinoceros, or tapir at a..., rhinoceros, or tapir was shipped; (h) The number, species, and purpose of importation of the elephant...

  14. 7 CFR 361.3 - Declarations and labeling.

    Science.gov (United States)

    2010-01-01

    ... declaration must state the kind, variety, and origin of each lot of seed or screenings and the use for which... names used on the label shall be the commonly accepted coined, chemical (generic), or abbreviated... distinctly contrasting color. Mercurials and similarly toxic substances include the following: Aldrin...

  15. Climate Change Impacts on pricing Long-Term Flood Insurance: A Comprehensive Study for the Netherlands

    NARCIS (Netherlands)

    Aerts, J.C.J.H.; Botzen, W.J.W.

    2011-01-01

    Recently long-term flood insurance contracts with a duration of 5, 10 or 15 years have been proposed as a solution for covering flood risk and mitigating increasing flood losses. Establishing a long-term relation between the policyholder and the insurer can provide better incentives to reduce risk

  16. The Impact of EuroSCORE II Risk Factors on Prediction of Long-Term Mortality.

    Science.gov (United States)

    Barili, Fabio; Pacini, Davide; D'Ovidio, Mariangela; Dang, Nicholas C; Alamanni, Francesco; Di Bartolomeo, Roberto; Grossi, Claudio; Davoli, Marina; Fusco, Danilo; Parolari, Alessandro

    2016-10-01

    The European System for Cardiac Operation Risk Evaluation (EuroSCORE) II has not been tested yet for predicting long-term mortality. This study was undertaken to evaluate the relationship between EuroSCORE II and long-term mortality and to develop a new algorithm based on EuroSCORE II factors to predict long-term survival after cardiac surgery. Complete data on 10,033 patients who underwent major cardiac surgery during a 7-year period were retrieved from three prospective institutional databases and linked with the Italian Tax Register Information System. Mortality at follow-up was analyzed with time-to-event analysis. The Kaplan-Meier estimates of survival at 1 and 5 were, respectively, 95.0% ± 0.2% and 84.7% ± 0.4%. Both discrimination and calibration of EuroSCORE II decreased in the prediction of 1-year and 5-year mortality. Nonetheless, EuroSCORE II was confirmed to be an independent predictor of long-term mortality with a nonlinear trend. Several EuroSCORE II variables were independent risk factors for long-term mortality in a regression model, most of all very low ejection fraction (less than 20%), salvage operation, and dialysis. In the final model, isolated mitral valve surgery and isolated coronary artery bypass graft surgery were associated with improved long-term survival. The EuroSCORE II cannot be considered a direct estimator of long-term risk of death, as its performance fades for mortality at follow-up longer than 30 days. Nonetheless, it is nonlinearly associated with long-term mortality, and most of its variables are risk factors for long-term mortality. Hence, they can be used in a different algorithm to stratify the risk of long-term mortality after surgery. Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  17. An assessment method of long-term radiation impacts to environment and public individual from tritium discharged by inland NPP

    International Nuclear Information System (INIS)

    Shangguan Zhihong; Huang Yanjun; Tao Yunliang

    2012-01-01

    In this paper, an assessment method of environmental impacts from long-term releases of tritium of inland nuclear power plant is proposed; the tritium concentrations in different environmental materials, including the two main chemical form HTO and OBT. and the radiation dose to public individuals including drinking water, food, inhalation. skin adsorption, are estimated based on the method and environmental parameters from typical inland NPP. The two discharge pathways, gaseous and liquid, are considered with particular concerns to drinking and irrigation ascribed to liquid discharge. This study would contribute to the assessment techniques of environmental impacts and safety of inland NPP. (authors)

  18. Examining the impact of modality and learning style preferences on recall of psychiatric nursing and pharmacology terms.

    Science.gov (United States)

    Wieland, Patience S; Willis, Jana; Peters, Michelle L; O'Toole, Robin S

    2018-07-01

    The purpose of this experimental research study was to explore how modality and learning style preferences impact non-prescribing, first-year Licensed Vocational Nurse (LVN) students' recall of vocabulary. Independent t-test results indicated a statistically significant mean difference in short-term recall of pharmacological and psychiatric terms, with learners receiving visual text instruction recalling significantly more vocabulary than learners receiving audio text instruction. A correlation was not found between learning preferences and vocabulary recall. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. Commercial satellite data as support to the additional protocol declarations

    International Nuclear Information System (INIS)

    Joensson, Camilla; Andersson, Christer

    2001-01-01

    Full text: Objectives - The overall objective of the project is to show how commercial satellite data can be used for safeguard purposes both at SKI and the International Atomic Energy Agency. Furthermore this project will support IAEA in its process to develop methods to make the best use of provided information such as digitised maps and satellite images. Finally it will give IAEA a case study of the usefulness of satellite data for change detection purposes. Background - The protocol calls among others for an extended/complete declaration of all nuclear fuel cycle-related research and development activities as well as sites where nuclear material is or was customarily used. The declaration shall include descriptions of all buildings at the sites as well as maps. In parallel to the development of the additional protocol IAEA has started to use a variety of measures/techniques both to verify that declarations are complete and correct but also to be able to come to the conclusion that a state has no undeclared nuclear material or undeclared nuclear activities. One such technique is the use of commercial satellite data. The IAEA is now in the process of evaluating the usefulness and effectiveness of such data for safeguard purposes. In order to come to a decision on how to use satellite data IAEA is highly dependant on support from member states which can provide results from case studies etc. Analysis - This project shall provide SKI with digitised maps and commercial satellite data by the means of GIS to verify the descriptions provided by two of the nuclear operators. Furthermore those digital data can be included in the declaration given to IAEA. The overall aim is to enhance the quality of the Swedish declaration including support to IAEA to develop methods to use commercial satellite data. Results - The paper will present experiences and mapping results made during the work. (author)

  20. [The Development of Long-Term Care Policies and the Impact on Nursing].

    Science.gov (United States)

    Wu, Shiao-Chi; Tsai, Yin-Yin; Yeh, Shin-Ting

    2015-10-01

    The government must reform and enhance current medical and long-term care services in order to respond effectively to societal ageing and labor shortage trends and to ensure sustainable operations. The post-acute care system should be reoriented on the home and community instead of the hospital. The Long Term Care Service Act integrates long-term care services that were previously dispersed amongst different departments, sets up a long-term care development fund, and improves the quality and allocation of long-term care services. Moreover, the Long Term Care Insurance Act will implement a bundle payment system to assist disabled families. The integration of automation and information technology will make long-term care more efficient. Although nurses are more skilled at elderly care and counseling than other community care professionals, nurses generally lack training in business management. Home and community-based services thus require better-trained manpower, opportunities to set care agents, and opportunities to offer flexible caring jobs. Therefore, nurses should strengthen their capabilities in post-acute care, business management, cooperation, and coordination.

  1. Predicting long-term citation impact of articles in social and personality psychology.

    Science.gov (United States)

    Haslam, Nick; Koval, Peter

    2010-06-01

    The citation impact of a comprehensive sample of articles published in social and personality psychology journals in 1998 was evaluated. Potential predictors of the 10-yr. citation impact of 1580 articles from 37 journals were investigated, including number of authors, number of references, journal impact factor, author nationality, and article length, using linear regression. The impact factor of the journal in which articles appeared was the primary predictor of the citations that they accrued, accounting for 30% of the total variance. Articles with greater length, more references, and more authors were cited relatively often, although the citation advantage of longer articles was not proportionate to their length. A citation advantage was also enjoyed by authors from the United States of America, Canada, and the United Kingdom. 37% of the variance in the total number of citations was accounted for by the study variables.

  2. Life cycle assessment of sewage sludge management options including long-term impacts after land application

    DEFF Research Database (Denmark)

    Yoshida, Hiroko; ten Hoeve, Marieke; Christensen, Thomas Højlund

    2018-01-01

    -toxic impact categories other than freshwater eutrophication. The sensitivity analysis showed that the results were sensitive to soil and precipitation conditions. The ranking of scenarios was affected by local conditions for marine eutrophication. Overall, the present study highlighted the importance...... of including all sludge treatment stages and conducting a detailed N flow analysis, since the emission of reactive N into the environment is the major driver for almost all non-toxic impact categories....... happened. In general, the INC scenario performed better than or comparably to the scenarios with land application of the sludge. Human toxicity (non-carcinogenic) and eco-toxicity showed the highest normalised impact potentials for all the scenarios with land application. In both categories, impacts were...

  3. Long-term variability and impact on human health of biologically active UV radiation in Moscow

    Science.gov (United States)

    Zhdanova, Ekaterina; Chubarova, Natalia

    2014-05-01

    Measurements of erythemally weighted UV irradiance (Qer) have been performed at the Meteorological Observatory of Moscow State University since 1999 with the UVB-1 YES pyranometers. These types of devices are broadband with a spectral sensitivity curve close to the action spectrum of erythema. Main uncertainties of UVB-1 YES measurements include the difference in spectral curves of the instrument and the action spectrum of erythema, as well as the deviation from the cosine law. These uncertainties were taken into account in the database of Qer measurements (Chubarova, 2008. Additional corrections of UVB-1 measurements at low ambient temperatures have been made. We analyze interannual, seasonal and diurnal Qer changes over the time period 1999-2012. In addition, the comparisons with the results of UV reconstruction model (Chubarova, 2008) are made. This model allows us to evaluate relative changes in Qer due to variations in total ozone, effective cloud amount transmission, aerosol and cloud optical thickness since 1968. It is important to note that the main reason for UV irradiance monitoring development is the strong influence of UV irradiance on the biosphere and especially on human health mainly on human skin (CIE, 1993, CIE, 2006) and eyes (Oriowo, M. et al., 2001). Based on the detailed studies we have shown the possibility of utilizing UVB-1 pyranometers for measuring the eye-damage UV radiation. Parallel measurements by the Bentham DTM-300 spectrometer and the UVB-1 YES pyranometer at the Innsbruck Medical University (Austria) have provided us the calibration factor in eye-damage units for this broadband instrument. Influence of main geophysical factors on different types of UV irradiance is estimated by means the RAF ideology (Booth, Madronich, 1994). We discuss the responses of different types of biologically active UV radiation to the impact of various atmospheric factors. The UV conditions (deficiency, optimum, excess for human) are analyzed according to

  4. Long-term ionizing radiation impact on seed progeny of common reed in water bodies of the Chernobyl exclusive zone

    International Nuclear Information System (INIS)

    Shevtsova, N.L.; Yavnyuk, A.A.; Gudkov, D.Yi.

    2012-01-01

    Results of the investigation of common reed's (Phragmites australis (Trin) Ex. Steud.) biological characteristics under conditions of long-term ionizing radiation impact are represented. Indices of seeds' vitality and disorders are analyzed. Low vitality indices, significant ontogenesis disorders, and high percent of abnormalities of germs are determined in water bodies, where littoral plants receive the absorbed dose in a low-dose range of 1-12 cGy year -1 .

  5. Guillain-Barr? Syndrome: Prevalence and Long-Term Factors Impacting Bladder Function in an Australian Community Cohort

    OpenAIRE

    Amatya, Bhasker; Khan, Fary; Whishaw, Michael; Pallant, Julie F.

    2013-01-01

    Background and Purpose Urinary dysfunction is associated with significant morbidity in persons with Guillain-Barr? Syndrome (GBS). The aim of this study was to describe prevalence and long-term impact of bladder dysfunction on daily activities and quality of life (QoL) in persons in chronic phase of GBS and to examine the relationships between commonly used continence measures in this cohort. Methods Prospective cohort (n=66) following GBS treatment (1996-2009) was recruited from a tertiary h...

  6. Long-term regional shifts in plant community composition are largely explained by local deer impact experiments.

    Directory of Open Access Journals (Sweden)

    Katie Frerker

    Full Text Available The fact that herbivores and predators exert top-down effects to alter community composition and dynamics at lower trophic levels is no longer controversial, yet we still lack evidence of the full nature, extent, and longer-term effects of these impacts. Here, we use results from a set of replicated experiments on the local impacts of white-tailed deer to evaluate the extent to which such impacts could account for half-century shifts in forest plant communities across the upper Midwest, USA. We measured species' responses to deer at four sites using 10-20 year-old deer exclosures. Among common species, eight were more abundant outside the exclosures, seven were commoner inside, and 16 had similar abundances in- and outside. Deer herbivory greatly increased the abundance of ferns and graminoids and doubled the abundance of exotic plants. In contrast, deer greatly reduced tree regeneration, shrub cover (100-200 fold in two species, plant height, plant reproduction, and the abundance of forbs. None of 36 focal species increased in reproduction or grew taller in the presence of deer, contrary to expectations. We compared these results to data on 50-year regional shifts in species abundances across 62 sites. The effects of herbivory by white-tailed deer accurately account for many of the long-term regional shifts observed in species' abundances (R2 = 0.41. These results support the conjecture that deer impacts have driven many of the regional shifts in forest understory cover and composition observed in recent decades. Our ability to link results from shorter-term, local experiments to regional long-term studies of ecological change strengthens the inferences we can draw from both approaches.

  7. Impacts of supersymmetric higher derivative terms on inflation models in supergravity

    International Nuclear Information System (INIS)

    Aoki, Shuntaro; Yamada, Yusuke

    2015-01-01

    We show the effects of supersymmetric higher derivative terms on inflation models in supergravity. The results show that such terms generically modify the effective kinetic coefficient of the inflaton during inflation if the cut off scale of the higher derivative operators is sufficiently small. In such a case, the η-problem in supergravity does not occur, and we find that the effective potential of the inflaton generically becomes a power type potential with a power smaller than two

  8. Root length and alveolar bone level of impacted canines and adjacent teeth after orthodontic traction: a long-term evaluation

    Science.gov (United States)

    da SILVA, Aldir Cordeiro; CAPISTRANO, Anderson; de ALMEIDA-PEDRIN, Renata Rodrigues; CARDOSO, Maurício de Almeida; CONTI, Ana Cláudia de Castro Ferreira; CAPELOZZA, Leopoldino

    2017-01-01

    Abstract Objective The aim of this retrospective study was to evaluate the long-term effects of orthodontic traction on root length and alveolar bone level in impacted canines and adjacent teeth. Material and Methods Sample consisted of 16 patients (nine males and seven females), mean initial age 11 years and 8 months presenting with unilaterally maxillary impacted canines, palatally displaced, treated with the same surgical and orthodontic approach. Teeth from the impacted-canine side were assigned as Group I (GI), and contralateral teeth as control, Group II (GII). The mean age of patients at the end of orthodontic treatment was 14 years and 2 months and the mean post-treatment time was 5 years and 11 months. Both contralateral erupted maxillary canines and adjacent teeth served as control. Root length and alveolar bone level (buccal and palatal) were evaluated on cone-beam computed tomography (CBCT) images. The comparison of root length and alveolar bone level changes between groups were assessed by applying paired t-test, at a significance level of 5% (p<0.05). Results There were no statistically significant differences in root length and buccal and palatal bone levels of canines and adjacent teeth among groups. Conclusions Impacted canine treatment by closed-eruption technique associated with canine crown perforation, has a minimal effect on root length and buccal and palatal alveolar bone level in both canine and adjacent teeth, demonstrating that this treatment protocol has a good long-term prognosis. PMID:28198979

  9. Long term impact of emotional, social and cognitive intelligence competencies and GMAT on career and life satisfaction and career success.

    Science.gov (United States)

    Amdurer, Emily; Boyatzis, Richard E; Saatcioglu, Argun; Smith, Melvin L; Taylor, Scott N

    2014-01-01

    Career scholars have called for a broader definition of career success by inviting greater exploration of its antecedents. While success in various jobs has been predicted by intelligence and in other studies by competencies, especially in management, long term impact of having intelligence and using competencies has not been examined. Even in collegiate outcome studies, few have examined the longer term impact on graduates' careers or lives. This study assesses the impact of demonstrated emotional, social, and cognitive intelligence competencies assessed at graduation and g measured through GMAT at entry from an MBA program on career and life satisfaction, and career success assessed 5 to 19 years after graduation. Using behavioral measures of competencies (i.e., as assessed by others), we found that emotional intelligence competencies predict career satisfaction and success. Adaptability had a positive impact, but influence had the opposite effect on these career measures and life satisfaction. Life satisfaction was negatively affected by achievement orientation and positively affected by teamwork. Current salary, length of marriage, and being younger at time of graduation positively affect all three measures of life and career satisfaction and career success. GMAT (as a measure of g) predicted life satisfaction and career success to a slight but significant degree in the final model analyzed. Meanwhile, being female and number of children positively affected life satisfaction but cognitive intelligence competencies negatively affected it, and in particular demonstrated systems thinking was negative.

  10. Long term impact of emotional, social and cognitive intelligence competencies and GMAT on career and life satisfaction and career success

    Science.gov (United States)

    Amdurer, Emily; Boyatzis, Richard E.; Saatcioglu, Argun; Smith, Melvin L.; Taylor, Scott N.

    2014-01-01

    Career scholars have called for a broader definition of career success by inviting greater exploration of its antecedents. While success in various jobs has been predicted by intelligence and in other studies by competencies, especially in management, long term impact of having intelligence and using competencies has not been examined. Even in collegiate outcome studies, few have examined the longer term impact on graduates' careers or lives. This study assesses the impact of demonstrated emotional, social, and cognitive intelligence competencies assessed at graduation and g measured through GMAT at entry from an MBA program on career and life satisfaction, and career success assessed 5 to 19 years after graduation. Using behavioral measures of competencies (i.e., as assessed by others), we found that emotional intelligence competencies predict career satisfaction and success. Adaptability had a positive impact, but influence had the opposite effect on these career measures and life satisfaction. Life satisfaction was negatively affected by achievement orientation and positively affected by teamwork. Current salary, length of marriage, and being younger at time of graduation positively affect all three measures of life and career satisfaction and career success. GMAT (as a measure of g) predicted life satisfaction and career success to a slight but significant degree in the final model analyzed. Meanwhile, being female and number of children positively affected life satisfaction but cognitive intelligence competencies negatively affected it, and in particular demonstrated systems thinking was negative. PMID:25566128

  11. Long Term Impact of Emotional, Social and Cognitive Intelligence Competencies and GMAT on Career and Life Satisfaction and Career Success

    Directory of Open Access Journals (Sweden)

    Emily eAmdurer

    2014-12-01

    Full Text Available ABSTRACTCareer scholars have called for a broader definition of career success by inviting greater exploration of its antecedents. While success in various jobs has been predicted by intelligence and in other studies by competencies, especially in management, long term impact of having intelligence and using competencies has not been examined. Even in collegiate outcome studies, few have examined the longer term impact on graduates’ careers or lives. This study assesses the impact of demonstrated emotional, social, and cognitive intelligence competencies assessed at graduation and g measured through GMAT at entry from an MBA program on career and life satisfaction, and career success assessed 5 to 19 years after graduation. Using behavioral measures of competencies (i.e., as assessed by others, we found that emotional intelligence competencies predict career satisfaction and success. Adaptability had a positive impact, but influence had the opposite effect on these career measures and life satisfaction. Life satisfaction was negatively affected by achievement orientation and positively affected by teamwork. Current salary, length of marriage, and being younger at time of graduation positively affect all three measures of life and career satisfaction and career success. GMAT (as a measure of g predicted life satisfaction and career success to a slight but significant degree in the final model analyzed. Meanwhile, being female and number of children positively affected life satisfaction but cognitive intelligence competencies negatively affected it, and in particular demonstrated systems thinking was negative.

  12. Color Terms and Color Concepts

    Science.gov (United States)

    Davidoff, Jules

    2006-01-01

    In their lead articles, both Kowalski and Zimiles (2006) and O'Hanlon and Roberson (2006) declare a general relation between color term knowledge and the ability to conceptually represent color. Kowalski and Zimiles, in particular, argue for a priority for the conceptual representation in color term acquisition. The complexities of the interaction…

  13. Proposition of declaration tending to create a commission of inquiry relative to the impact in nourishment and on health of foodstuff treated by irradiation; Proposition de resolution tendant a creer une commission d'enquete relative a l'impact dans l'alimentation et sur la sante des denrees traitees par radiations ionisantes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    In application of articles 140 and following of the regulation, is created a commission of inquiry with thirty members relative to the impact in foodstuff and on health of irradiated food. It should examines the respect of the regulation concerning the labelling, the production and imports; it should determine the real place of this food in the French diet and the impact on this diet that could imply an opening of the market to the food imported from third country to european Union; it should evaluate the risk for human and animal health of their consumption. (N.C.)

  14. Non-declarative sequence learning does not show savings in relearning.

    Science.gov (United States)

    Keisler, Aysha; Willingham, Daniel T

    2007-04-01

    Researchers have utilized the savings in relearning paradigm in a variety of settings since Ebbinghaus developed the tool over a century ago. In spite of its widespread use, we do not yet understand what type(s) of memory are measurable by savings. Specifically, can savings measure both declarative and non-declarative memories? The lack of conscious recollection of the encoded material in some studies indicates that non-declarative memories may show savings effects, but as all studies to date have used declarative tasks, we cannot be certain. Here, we administer a non-declarative task and then measure savings in relearning the material declaratively. Our results show that while material outside of awareness may show savings effects, non-declarative sequence memory does not. These data highlight the important distinction between memory without awareness and non-declarative memory.

  15. An approach to microstructure quantification in terms of impact properties of HSLA pipeline steels

    Energy Technology Data Exchange (ETDEWEB)

    Gervasyev, Alexey [Department of Materials Science and Engineering, Ghent University (Belgium); R& D Center TMK, Ltd., Chelyabinsk (Russian Federation); Carretero Olalla, Victor [SKF Belgium NV/SA, Brussels (Belgium); Sidor, Jurij [Department of Mechanical Engineering, University of West Hungary, Szombathely (Hungary); Sanchez Mouriño, Nuria [ArcelorMittal Global R& D/OCAS NV, Gent (Belgium); Kestens, Leo A.I.; Petrov, Roumen H. [Department of Materials Science and Engineering, Ghent University (Belgium); Department of Materials Science and Engineering, Delft University of Technology (Netherlands)

    2016-11-20

    Several thermo-mechanical controlled processing (TMCP) schedules of a modern pipeline steel were executed using a laboratory mill to investigate both the TMCP parameters influence on the ductile properties and the microstructure and texture evolution during TMCP. Impact fracture toughness was evaluated by means of instrumented Charpy impact test and results were correlated with the metallurgical characterization of the steel via electron backscattered diffraction (EBSD) technique. It is shown that the ductile crack growth observed in the impact test experiments can be reasonably correlated with the Morphology Clustering (MC) and the Cleavage Morphology Clustering (CMC) parameters, which incorporate size, shape, and crystallographic texture features of microstructure elements. The mechanism of unfavorable texture formation during TMCP is explained by texture changes occurring between the end of finish rolling and the start of accelerated cooling.

  16. An Assessment of the UN's Millennium Development Goals and its Millennium Declaration

    OpenAIRE

    Tisdell, Clement A.

    2006-01-01

    The United Nations’ Millennium Declaration, passed by the General Assembly in September 2000, is assessed with particular attention being given to the Millennium Development Goals and associated targets outlined in the Declaration. The focus of the article is not so much on the extent to which these goals are being met but on the adequacy of the Declaration itself. The fundamental values outlined in the Declaration are listed and assessed. The Millennium Development Goals are means for the at...

  17. Scenarios of long-term farm structural change for application in climate change impact assessment

    NARCIS (Netherlands)

    Mandryk, M.; Reidsma, P.; Ittersum, van M.K.

    2012-01-01

    Towards 2050, climate change is one of the possible drivers that will change the farming landscape, but market, policy and technological development may be at least equally important. In the last decade, many studies assessed impacts of climate change and specific adaptation strategies. However,

  18. Long-Term Impact of the Farm Financial Analysis Training Curriculum on FSA Borrowers in Pennsylvania

    Science.gov (United States)

    Balliet, Kenneth L.; Douglass, Mark B.; Hanson, Gregory

    2010-01-01

    The Farm Financial Analysis Training (FFAT) course covers fundamental skills and concepts in liquidity, profitability, solvency, and efficiency. The research reported here identifies and measures the impacts of FFAT on participants including: 1) perceived gains in knowledge, 2) changes in management behavior, 3) changes in specific farm assets and…

  19. The Impact of Long-Term Dental Health Education on Oral Hygiene Behavior.

    Science.gov (United States)

    Houle, Bonnie A.

    1982-01-01

    A study evaluated the impact of five years' exposure to a dental health curriculum on the oral hygiene of fifth-grade students. Findings of the study indicate that a well-designed dental health curriculum based on cognitive and behavioral objectives can result in a greater accumulation of dental health knowledge. (JN)

  20. Impact of Long-Term Communication Training on Managerial Style and Perceptions of Organization.

    Science.gov (United States)

    Cullinane, Laura E.; Stacks, Don W.

    A study examined the impact of a working commitment to corporate communication and corporate communication education on perceptions of management and managerial style and the more general perceptions of the organization. Subjects, 15 male mid-level managers at a large southeastern chemical plant that had in place a continuing corporate…

  1. The long-term fiscal impact of funding cuts to Danish public fertility clinics

    NARCIS (Netherlands)

    Connolly, Mark P.; Postma, Maarten J.; Crespi, Simone; Andersen, Anders Nyboe; Ziebe, Soren

    2011-01-01

    This study evaluated the fiscal impact attributed to recent policy changes that limited funding to public fertility clinics in Denmark. Taking into consideration that introducing patient co-payments will influence the numbers of couples treated, the number of children born every year from assisted

  2. Long-term impacts of nitrogen deposition on coastal plant communities

    DEFF Research Database (Denmark)

    Pakeman, Robin J.; Brooker, Rob; Alexander, Jim

    2016-01-01

    , Fixed dune, Heath, Slack and Tall grass mire communities and despite falls in EIV-N for Improved grass, Strand and Wet grassland. The increase in EIV-N was highly correlated to the cumulative deposition between the surveys, and for sites in south-east Scotland, eutrophication impacts appear severe...

  3. Long-term costs and health impact of continued global fund support for antiretroviral therapy

    NARCIS (Netherlands)

    J. Stover (John); E.L. Korenromp (Eline); M. Blakley (Matthew); R. Komatsu (Ryuichi); K.M. Viisainen (Kirsi); L. Bollinger (Lori); R. Atun (Rifat)

    2011-01-01

    textabstractBackground: By the end of 2011 Global Fund investments will be supporting 3.5 million people on antiretroviral therapy (ART) in 104 low- and middle-income countries. We estimated the cost and health impact of continuing treatment for these patients through 2020. Methods and Findings:

  4. estimating the short-term impact of fire on productivity in a semi-arid

    African Journals Online (AJOL)

    Landbou

    42nd Congress of the South African Society for Animal Science. 38 ..... Scientific knowledge of the impact of veld fires on the functioning of the ecosystem can therefore lead to. The South African ... (Version 8.2) SAS Institute Inc., Carey, North.

  5. Long-term impact of war on healthcare costs: an eight-country study

    NARCIS (Netherlands)

    Sabes-Figuera, R.; McCrone, P.; Bogic, M.; Ajdukovic, D.; Franciskovic, T.; Colombini, N.; Kucukalic, A.; Lecic-Tosevski, D.; Morina, N.; Popovski, M.; Schützwohl, M.; Priebe, S.

    2012-01-01

    Objective Exposure to war can negatively affect health and may impact on healthcare costs. Estimating these costs and identifying their predictors is important for appropriate service planning. We aimed to measure use of health services in an adult population who had experienced war in the

  6. Short-term economic impact of Foot and Mouth disease outbreak in ...

    African Journals Online (AJOL)

    Direct and indirect areas that contribute to financial losses were identified for the period of observation (95 days) the greatest direct financial impact due to milk ... by purchase of additional feeds (13.6%) and culling of milk cows that developed chronic mastitis (12.5%). the other direct costs were extra labor inputs (8.9%), ...

  7. Short-term impact of dry olive mill residue addition to soil on the resident microbiota

    Czech Academy of Sciences Publication Activity Database

    Sampedro, I.; Giubilei, M. A.; Cajthaml, Tomáš; Federici, E.; Federici, F.; Petruccioli, M.; D´Annibale, A.

    2009-01-01

    Roč. 100, č. 23 (2009), s. 6098-6106 ISSN 0960-8524 R&D Projects: GA MŠk LC06066 Institutional research plan: CEZ:AV0Z50200510 Keywords : Dry olive mill residue * Microbial community profiling * Toxicity Subject RIV: EE - Microbiology, Virology Impact factor: 4.253, year: 2009

  8. Projected climate change impacts and short term predictions on staple crops in Sub-Saharan Africa

    Science.gov (United States)

    Mereu, V.; Spano, D.; Gallo, A.; Carboni, G.

    2013-12-01

    Agriculture in Sub-Saharan Africa (SSA) drives the economy of many African countries and it is mainly rain-fed agriculture used for subsistence. Increasing temperatures, changed precipitation patterns and more frequent droughts may lead to a substantial decrease of crop yields. The projected impacts of future climate change on agriculture are expected to be significant and extensive in the SSA due to the shortening of the growing seasons and the increasing of water-stress risk. Differences in Agro-Ecological Zones and geographical characteristics of SSA influence the diverse impacts of climate change, which can greatly differ across the continent and within countries. The vulnerability of African Countries to climate change is aggravated by the low adaptive capacity of the continent, due to the increasing of its population, the widespread poverty, and other social factors. In this contest, the assessment of climate change impact on agricultural sector has a particular interest to stakeholder and policy makers, in order to identify specific agricultural sectors and Agro-Ecological Zones that could be more vulnerable to changes in climatic conditions and to develop the most appropriate policies to cope with these threats. For these reasons, the evaluation of climate change impacts for key crops in SSA was made exploring climate uncertainty and focusing on short period monitoring, which is particularly useful for food security and risk management analysis. The DSSAT-CSM (Decision Support System for Agrotechnology Transfer - Cropping System Model) software, version 4.5 was used for the analysis. Crop simulation models included in DSSAT-CSM are tools that allow to simulate physiological process of crop growth, development and production, by combining genetic crop characteristics and environmental (soil and weather) conditions. For each selected crop, the models were used, after a parameterization phase, to evaluate climate change impacts on crop phenology and production

  9. 77 FR 76063 - Agency Information Collection Activities: Declaration for Free Entry of Unaccompanied Articles

    Science.gov (United States)

    2012-12-26

    ... Activities: Declaration for Free Entry of Unaccompanied Articles AGENCY: U.S. Customs and Border Protection... collection requirement concerning the Declaration for Free Entry of Unaccompanied Articles (Form 3299). This... concerning the following information collection: Title: Declaration for Free Entry of Unaccompanied Articles...

  10. 76 FR 11254 - Agency Information Collection Activities: Declaration of Unaccompanied Articles

    Science.gov (United States)

    2011-03-01

    ... Activities: Declaration of Unaccompanied Articles AGENCY: U.S. Customs and Border Protection (CBP... collection requirement concerning the Declaration of Unaccompanied Articles (CBP Form 255). This request for...: Title: Declaration of Unaccompanied Articles. OMB Number: 1651-0030. Form Number: CBP Form 255. Abstract...

  11. 78 FR 69101 - Agency Information Collection Activities: Declaration of the Ultimate Consignee That Articles...

    Science.gov (United States)

    2013-11-18

    ... Activities: Declaration of the Ultimate Consignee That Articles Were Exported for Temporary Scientific or... the Declaration of the Ultimate Consignee that Articles were Exported for Temporary Scientific or...: Title: Declaration of the Ultimate Consignee that Articles were Exported for Temporary Scientific or...

  12. 75 FR 65696 - Ohio Disaster #OH-00025 Declaration of Economic Injury

    Science.gov (United States)

    2010-10-26

    ... Counties: Auglaize, Mercer. Contiguous Counties: Ohio: Allen, Darke, Hardin, Logan, Shelby, Van Wert... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12359] Ohio Disaster OH-00025 Declaration of... Economic Injury Disaster Loan (EIDL) declaration for the State of Ohio, dated 10/19/2010. Incident: Toxic...

  13. Teaching the Universal Declaration of Human Rights in a U.S. Government Course.

    Science.gov (United States)

    Rosen, Philip

    1990-01-01

    Discusses the United Nations Universal Declaration of Human Rights as a vehicle for learning democratic and humanistic values. Provides goals for instruction about the Declaration. Compares the Declaration to U.S. Supreme Court cases and congressional acts, and suggests classroom activities using it. Includes an appendix on Supreme Court cases and…

  14. 19 CFR 4.75 - Incomplete manifest; incomplete export declarations; bond.

    Science.gov (United States)

    2010-04-01

    ... 1302-A (see § 4.63) in accordance with 46 U.S.C. 91, or all required shipper's export declarations (see... declarations; bond. 4.75 Section 4.75 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND... export declarations have been filed with the port director: Albania Bulgaria Cambodia China, People's...

  15. 77 FR 6135 - Agency Information Collection Activities: Cargo Manifest/Declaration, Stow Plan, Container Status...

    Science.gov (United States)

    2012-02-07

    ... Activities: Cargo Manifest/ Declaration, Stow Plan, Container Status Messages and Importer Security Filing... the Paperwork Reduction Act: Cargo Manifest/Declaration, Stow Plan, Container Status Messages and.../Declaration, Stow Plan, Container Status Messages and Importer Security Filing. OMB Number: 1651-0001. Form...

  16. 78 FR 44186 - Colorado Disaster # CO-00058 Declaration of Economic Injury

    Science.gov (United States)

    2013-07-23

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13662] Colorado Disaster CO-00058 Declaration... notice of an Economic Injury Disaster Loan (EIDL) declaration for the State of Colorado, dated 07/15/2013... areas have been determined to be adversely affected by the disaster: Primary Counties: Hinsdale, Mineral...

  17. Impact of Short-Term Training in Social Cognition in Preschoolers with Externalizing Behavior

    Science.gov (United States)

    Houssa, Marine; Jacobs, Emilie; Nader-Grosbois, Nathalie

    2017-01-01

    In two experimental and exploratory studies, we wanted to test the differentiated effects on preschoolers with externalizing behavior (EB) of two short-term social information processing (SIP) and Theory of Mind (ToM) training sessions, in comparison with typically developing (TD) preschoolers or with preschoolers with EB whom didn't receive…

  18. The Impact of Pointing on the Short-Term Memory (STM) of Heterophonic Homographs

    Science.gov (United States)

    Vaknin-Nusbaum, Vered; Miller, Paul

    2014-01-01

    This study entailed two short-term memory (STM) experiments investigating the importance of vowel diacritics for the temporary retention of three distinct Hebrew word list types: heterophonic homographs, non-homographs and homophonic homographs. Eighty university students participated in each experiment, with half of them tested with word lists…

  19. Speaking up and Speaking Out? Long-Term Impact of Critical Multicultural Pedagogy

    Science.gov (United States)

    Flynn, Jill Ewing

    2017-01-01

    This study explores the long-term effects of critical multicultural pedagogy on seven adolescents. Four years later, participants continued to demonstrate awareness of privilege and racism, yet few were actively engaged in antiracist work. Participants also expressed disillusionment and lamented the lack of productive discussions of critical…

  20. Long-term management impacts on carbon storage in Lake States forests

    Science.gov (United States)

    Matthew Powers; Randall Kolka; Brian Palik; Rachel McDonald; Martin. Jurgensen

    2011-01-01

    We examined carbon storage following 50+ years of forest management in two long-term silvicultural studies in red pine and northern hardwood ecosystems of North America’s Great Lakes region. The studies contrasted various thinning intensities (red pine) or selection cuttings, shelterwoods, and diameter-limit cuttings (northern hardwoods) to unmanaged controls of...

  1. Long-term impacts of mega-projects: the discount rate

    NARCIS (Netherlands)

    Koopmans, C.; Rietveld, P.; Priemus, H.; van Wee, B.

    2013-01-01

    In social cost-benefit analysis (SCBA), discount rates are used to convert costs and benefits that occur at different points in time, to present values that can be added and subtracted. Especially if important costs and benefits occur in the long term (more than say 30 years), the discount rate may

  2. Impact of Auditory Selective Attention on Verbal Short-Term Memory and Vocabulary Development

    Science.gov (United States)

    Majerus, Steve; Heiligenstein, Lucie; Gautherot, Nathalie; Poncelet, Martine; Van der Linden, Martial

    2009-01-01

    This study investigated the role of auditory selective attention capacities as a possible mediator of the well-established association between verbal short-term memory (STM) and vocabulary development. A total of 47 6- and 7-year-olds were administered verbal immediate serial recall and auditory attention tasks. Both task types probed processing…

  3. Understanding long-term impacts of R&D funding: The EU framework programme

    NARCIS (Netherlands)

    Arnold, Erik

    2012-01-01

    Despite a large and growing effort in the evaluation of public R&D funding programmes, we know surprisingly little about their long-term effects. This is a pity, because the conventional justifications for state intervention in research depend upon phenomena such as the production and use of public

  4. Impact of long-term HPN on daily life in adults

    NARCIS (Netherlands)

    Persoon, Anke; Huisman-de Waal, Getty; Naber, Ton A.; Schoonhoven, Lisette; Tas, Tirzah; Sauerwein, Hans; van Achterberg, Theo

    2005-01-01

    Home parenteral nutrition (HPN) is a therapy that changes life radically and often means lifelong dependence on parenteral feeding. The aim of this study was to gain insight into problems experienced by adult patients who were dependent on long-term HPN. A survey was performed on all patients at the

  5. Impact of long-term HPN on daily life in adults.

    NARCIS (Netherlands)

    Persoon, A.; Huisman-de Waal, G.J.; Naber, A.H.J.; Schoonhoven, L.; Tas, T.; Sauerwein, H.P.; Achterberg, T. van

    2005-01-01

    BACKGROUND AND AIMS: Home parenteral nutrition (HPN) is a therapy that changes life radically and often means lifelong dependence on parenteral feeding. The aim of this study was to gain insight into problems experienced by adult patients who were dependent on long-term HPN. METHODS: A survey was

  6. Stress steroid levels and the short-term impact of routine dehorning ...

    African Journals Online (AJOL)

    Routine dehorning procedures resulted in a short-term stress response expressed by a significant increase in fGCM levels 48 h post-dehorning, with stress steroid levels returning to pre-dehorning concentrations 72 h after the procedure. Keywords: faecal glucocorticoid metabolites, non-invasive hormone monitoring, ...

  7. Action for declaration of annulment of reactor construction permit dismissed

    International Nuclear Information System (INIS)

    Anon.

    1982-01-01

    The Higher Administrative Court of Rheinland Pfalz has confirmed two decisions by the Koblenz Administrative Court dismissing an actions to declare the annulment of the partial construction permit issued for the Muelheim-Kaerlich reactor. Appeal was not admitted. The plaintiffs, who are under age and were represented by their father, are permanently resident in Schleswig-Holstein, at about 470 km from the site and have a further residence in Mainz, about 60 km away from the site. They plead to have a legitimate interest in the declaration of nullity on the grounds of the uncertainty created in legal matters by the delivery of the permit and its being unconstitutional as well as for ideological and religious reasons. The ruling deals also with the importance of the distance from the site of a nuclear reactor, which is considered to be such as to exclude the 'necessary spatial relation'. (orig./HP) [de

  8. Non-declarative memory in the rehabilitation of amnesia.

    Science.gov (United States)

    Cavaco, S; Malec, J F; Bergquist, T

    2005-09-01

    The ability of amnesic patients to learn and retain non-declarative information has been consistently demonstrated in the literature. This knowledge provided by basic cognitive neuroscience studies has been widely neglected in neuropsychological rehabilitation of memory impaired patients. This study reports the case of a 43 year old man with severe amnesia following an anterior communicating artery (ACoA) aneurysm rupture. The patient integrated a comprehensive (holistic) day treatment programme for rehabilitation of brain injury. The programme explored the advantages of using preserved non-declarative memory capacities, in the context of commonly used rehabilitation approaches (i.e. compensation for lost function and domain-specific learning). The patient's ability to learn and retain new cognitive and perceptual-motor skills was found to be critical for the patient's improved independence and successful return to work.

  9. Impacts of short-term heatwaves on sun-induced chlorophyll fluorescence(SiF) in temperate tree species

    Science.gov (United States)

    Wang, F.; Gu, L.; Guha, A.; Han, J.; Warren, J.

    2017-12-01

    The current projections for global climate change forecast an increase in the intensity and frequency of extreme climatic events, such as droughts and short-term heat waves. Understanding the effects of short-term heat wave on photosynthesis process is of critical importance to predict global impacts of extreme weather event on vegetation. The diurnal and seasonal characteristics of SIF emitted from natural vegetation, e.g., forest and crop, have been studied at the ecosystem-scale, regional-scale and global-scale. However, the detailed response of SIF from different plant species under extremely weather event, especially short-term heat wave, have not been reported. The purpose of this study was to study the response of solar-induced chlorophyll fluorescence, gas exchange and continuous fluorescence at leaf scale for different temperate tree species. The short-term heatwave experiment was conducted using plant growth chamber (CMP6050, Conviron Inc., Canada). We developed an advanced spectral fitting method to obtain the plant SIF in the plant growth chamber. We compared SIF variation among different wavelength and chlorophyll difference among four temperate tree species. The diurnal variation of SIF signals at leaf-scales for temperate tree species are different under heat stress. The SIF response at leaf-scales and their difference for four temperate tree species are different during a cycle of short-term heatwave stress. We infer that SIF be used as a measure of heat tolerance for temperate tree species.

  10. Declarative Modelling and Safe Distribution of Healthcare Workflows

    DEFF Research Database (Denmark)

    Hildebrandt, Thomas; Mukkamala, Raghava Rao; Slaats, Tijs

    2012-01-01

    We present a formal technique for safe distribution of workflow processes described declaratively as Nested Condition Response (NCR) Graphs and apply the technique to a distributed healthcare workflow. Concretely, we provide a method to synthesize from a NCR Graph and any distribution of its events......-organizational case management. The contributions of this paper is to adapt the technique to allow for nested processes and milestones and to apply it to a healthcare workflow identified in a previous field study at danish hospitals....

  11. Classified installations for environmental protection subject to declaration. Tome 2

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    Legislation concerning classified installations govern most of industries or dangerous or pollutant activities. This legislation aims to prevent risks and harmful effects coming from an installation, air pollution, water pollution, noise, wastes produced by installations, even aesthetic bad effects. Pollutant or dangerous activities are defined in a list called nomenclature which obliged installations to a rule of declaration or authorization. Technical regulations ordered by the secretary of state for the environment are listed in tome 2

  12. Guillain-Barré Syndrome: Prevalence and Long-Term Factors Impacting Bladder Function in an Australian Community Cohort

    Science.gov (United States)

    Khan, Fary; Whishaw, Michael; Pallant, Julie F.

    2013-01-01

    Background and Purpose Urinary dysfunction is associated with significant morbidity in persons with Guillain-Barré Syndrome (GBS). The aim of this study was to describe prevalence and long-term impact of bladder dysfunction on daily activities and quality of life (QoL) in persons in chronic phase of GBS and to examine the relationships between commonly used continence measures in this cohort. Methods Prospective cohort (n=66) following GBS treatment (1996-2009) was recruited from a tertiary hospital and assessed using standardised measures for bladder dysfunction: American Urological Association (AUA) Symptom Index, Incontinence Impact Questionnaire, Urogenital Distress Inventory. Results Sixty-six participants (64% male, mean age 56 years, median disease duration of 6.1 years) completed the study. Of these more than half reported nocturia and one-third reported urinary urgency and frequency. Urinary problems impacted on participants' daily activities: physical recreation (21%), emotional health and mood (17%), entertainment (14%), participation and mobility (>30 min) (12%), and performance of household chores (8%). Since GBS, 49% reported interference of urinary symptoms with daily life to some extent; and adverse impact on QoL (10.6%). Significant relationship between bladder symptoms; and the level of urogenital distress (p<0.001) and the impact of urinary problems (p<0.001), was noted. Higher scores on the bladder scales showed significant correlations with psychological, functional and participation scales. The single QoL item (AUA scale) correlated significantly with all other bladder scales (rho=0.63-0.86). This can be a potential 'screening tool' to identify patients for further assessment. Conclusions Bladder dysfunction in chronic phase of GBS is not well studied. More research in longer-term screening and outcomes for bladder intervention are needed for integrated care and to guide treating clinicians. PMID:23894237

  13. Differential impact of white matter hyperintensities on long-term outcomes in ischemic stroke patients with large artery atherosclerosis.

    Directory of Open Access Journals (Sweden)

    Minyoul Baik

    Full Text Available The presence of white matter hyperintensity (WMH is related to poor long-term outcomes in stroke patients. However, the long-term outcome is unknown in patients with both large artery atherosclerosis (LAA and WMH.We investigated the impact of WMH on long-term outcome in patients with LAA. Consecutive patients in a prospective stroke registry were included. Patients were followed for a median of 7.7 years (interquartile range, 5.6-9.7. The degree of WMH was assessed by Fazekas grade on fluid-attenuated inversion recovery images. Total WMH burden was calculated by summation of Fazekas scores in periventricular and deep white matter. Severe WMH was defined as total burden score ≥ 3.Among 2529 patients, 639 patients (25.3% were classified with the LAA subtype. After applying exclusion criteria, the data from 538 patients were analyzed. The mean patient age was 65.7 ± 10.3 years. Severe WMHs were found in 243 patients (45.2%. During follow-up, 200 patients (37.2% died. Cox regression analysis showed that LAA patients with severe WMH had a 1.50-fold (95% CI, 1.12-2.00, p = 0.007 higher death rate compared to those without. In the older age group (≥65 years, Cox regression revealed that patients with severe WMH had a 1.75-fold (95% CI, 1.15-2.65, p = 0.008 higher 5-year death rate, whereas the younger age group did not have this association.The degree of WMH might be a surrogate marker for long-term outcome in patients with LAA. Atherosclerotic burdens in both small and large arteries might impact long-term prognosis in ischemic stroke patients.

  14. Declarative and Procedural Working Memory: Common Principles, Common Capacity Limits?

    Directory of Open Access Journals (Sweden)

    Klus Oberauer

    2010-10-01

    Full Text Available Working memory is often described as a system for simultaneous storage and processing. Much research – and most measures of working-memory capacity – focus on the storage component only, that is, people's ability to recall or recognize items after short retention intervals. The mechanisms of processing information are studied in a separate research tradition, concerned with the selection and control of actions in simple choice situations, dual-task constellations, or task-switching setups. both research traditions investigate performance based on representations that are temporarily maintained in an active, highly accessible state, and constrained by capacity limits. In this article an integrated theoretical framework of declarative and procedural working memory is presented that relates the two domains of research to each other. Declarative working memory is proposed to hold representations available for processing (including recall and recognition, whereas procedural working memory holds representations that control processing (i. e., task sets, stimulus-response mappings, and executive control settings. The framework motivates two hypotheses: Declarative and procedural working memory have separate capacity limits, and they operate by analogous principles. The framework also suggests a new characterization of executive functions as the subset of processes governed by procedural working memory that has as its output a change in the conditions of operation of the working-memory system.

  15. IMPORTANT — Declaration of income for 2001 —

    CERN Multimedia

    Human Resources Division

    2002-01-01

    The local French tax authorities confirm that, in view of the particular procedure for income declaration for CERN members of the personnel, this year CERN income (as stated in the certificate of CERN remuneration provided by the Organization) may be exceptionally declared in either French Francs, or Euros (clearly specifying the currency selected). Practical information concerning the procedure for income declaration may be obtained at the following local information desks : Trésorerie deGex: Tuesday12 March 9 a.m. to 122 to 4 p.m. Trésorerie deFerney: Monday18 March 9 a.m. to 122 to 4 p.m. Trésorerie deDivonne: Thursday21 March 9 a.m. to 122 to 4 p.m. French tax authorities have also organised the following information services: Web site: http://www.impots.gouv.fr/ Minitel: 3615 IR Service Vocal Server: 08 36 67 10 10 Telephone information: 08 20 32 42 52 Human Resources Division Tel. 72838

  16. Long-term memory, sleep, and the spacing effect.

    Science.gov (United States)

    Bell, Matthew C; Kawadri, Nader; Simone, Patricia M; Wiseheart, Melody

    2014-01-01

    Many studies have shown that memory is enhanced when study sessions are spaced apart rather than massed. This spacing effect has been shown to have a lasting benefit to long-term memory when the study phase session follows the encoding session by 24 hours. Using a spacing paradigm we examined the impact of sleep and spacing gaps on long-term declarative memory for Swahili-English word pairs by including four spacing delay gaps (massed, 12 hours same-day, 12 hours overnight, and 24 hours). Results showed that a 12-hour spacing gap that includes sleep promotes long-term memory retention similar to the 24-hour gap. The findings support the importance of sleep to the long-term benefit of the spacing effect.

  17. Good Vibrations: The long term impact of a prison based music project

    OpenAIRE

    Wilson, David; Caulfield, Laura; Atherton, Susie

    2009-01-01

    There is growing awareness amongst policy makers and those working in the criminal justice system of the contribution that can be made by the arts in prisons, in particular by more innovative projects that are often provided by charities and voluntary organisations. Numerous research studies have suggested that projects — such as music and art programmes — that offer participants a creative outlet have a positive impact on offenders, not least by encouraging them to engage with further learni...

  18. The long term impact of the 1918 influenza pandemic in Norway

    OpenAIRE

    Bakken, Magnus Røthe; Husøy, Sigrid Johanne

    2016-01-01

    Advisor: Aline Bütikofer A growing literature show the negative effect of prenatal health shocks on childhood and adult outcomes. Several studies exploit disease outbreaks to find causal effects of in utero exposure on various outcomes. We build on the existing literature by applying theories of in utero health effects to Norwegian data. This thesis uses the 1918 Spanish Influenza pandemic as a natural experiment to investigate the impact of prenatal health shock on various ...

  19. Impact of childhood adversities on the short-term course of illness in psychotic spectrum disorders.

    Science.gov (United States)

    Schalinski, Inga; Fischer, Yolanda; Rockstroh, Brigitte

    2015-08-30

    Accumulating evidence indicates an impact of childhood adversities on the severity and course of mental disorders, whereas this impact on psychotic disorders remains to be specified. Effects of childhood adversities on comorbidity, on symptom severity of the Positive and Negative Syndrome Scale and global functioning across four months (upon admission, 1 and 4 months after initial assessment), as well as the course of illness (measured by the remission rate, number of re-hospitalizations and dropout rate) were evaluated in 62 inpatients with psychotic spectrum disorders. Adverse experiences (of at least 1 type) were reported by 73% of patients. Patients with higher overall level of childhood adversities (n=33) exhibited more co-morbid disorders, especially alcohol/substance abuse and dependency, and higher dropout rates than patients with a lower levels of adverse experiences (n=29), together with higher levels of positive symptoms and symptoms of excitement and disorganization. Emotional and physical neglect were particularly related to symptom severity. Results suggest that psychological stress in childhood affects the symptom severity and, additionally, a more unfavorable course of disorder in patients diagnosed with psychoses. This impact calls for its consideration in diagnostic assessment and psychiatric care. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  20. Long-term impact of prevention programs to promote effective parenting: lasting effects but uncertain processes.

    Science.gov (United States)

    Sandler, Irwin N; Schoenfelder, Erin N; Wolchik, Sharlene A; MacKinnon, David P

    2011-01-01

    This article reviews findings from 46 randomized experimental trials of preventive parenting interventions. The findings of these trials provide evidence of effects to prevent a wide range of problem outcomes and to promote competencies from one to 20 years later. However, there is a paucity of evidence concerning the processes that account for program effects. Three alternative pathways are proposed as a framework for future research on the long-term effects of preventive parenting programs: (a) through program effects on parenting skills, perceptions of parental efficacy, and reduction in barriers to effective parenting; (b) through program-induced reductions in short-term problems of youth that persist over time, improvements in youth adaptation to stress, and improvements in youth belief systems concerning the self and their relationships with others; and (c) through effects on contexts in which youth become involved and on youth-environment transactions.

  1. The Long-Term Impact of Educational and Health Spending on Unemployment Rates

    Directory of Open Access Journals (Sweden)

    ZAFER PIRIM

    2017-12-01

    Full Text Available This study used panel data regression analysis to evaluate the long-term effects of several measures of U.S. education expenditure on unemployment rates in 50 states and Washington D.C. over 25 years. The data included state-level statistics for fiscal effort, graduation rates, education spending per pupil, gross state product per capita, welfare spending, health spending, political party affiliation, union versus nonunion states, and unemployment rates. Results find that the best way to effectively reduce unemployment is investment in improving the quality of human capital through funding education. Findings specifically conclude that over the long term, investment in human capital through education as defined by per-pupil spending and health services could play a significant role in reducing unemployment rates.

  2. THE IMPACT OF THE ENGLISH ECONOMIC TERMS IN THE BUSINESS ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    COANCA MARIANA

    2010-12-01

    Full Text Available In terms of quantity, the English (American influence in the economic language is striking, remarkable. The adjustment of these terms is brief, relative, which is not a factor favoring the assimilation of loans, but is permissible, in principle, for Anglicisms. In what concerns the need for these loans, it can be deemed that the demarcation between necessary loans and luxury loans is not yet solid. Low frequency or isolated Anglicisms may be classified into the second category (some may even affect proper specialized communication. Even if enough Anglicisms recorded in the economic press will not remain in Romanian, "the era of the Internet, of globalization" , we may consider a greater influence of English in the economy (perhaps similar to computer science.

  3. From life cycle analysis approach to monetarisation of the impacts: an evaluation in term of decision process

    International Nuclear Information System (INIS)

    Darras, M.

    2002-01-01

    The life cycle analysis offers a new tool in the direction of integration of the multiple physical flows of matters around industrial processes and products, including the usage stage. Simultaneously, it stresses the multidimensional impact of the human activities, first in term of physical flows, but then in term of impact on the goals stated above. In this perspective, integrating framework for decision are needed, especially at the more global level. One of the proposed frameworks is the monetarisation and cost-benefit analysis, as an extension of the quantitative economy. The multi-dimensional choice, unfit for strict order choice, is reduce to one variable.In the presentation below, because of the importance of this approach in connection with Life Cycle Analysis and public policies, we concentrate on the;analysis of this framework. We will show that it might shed light on the decision process, especially if associated with its uncertainties, its limits in term of process or criteria taken into account, the indication of other social criteria not taken into account, and other method of evaluation. At the end, this is mainly a source for a better multi-criteria decision process. (author)

  4. Parents' experiences of pediatric palliative care and the impact on long-term parental grief.

    Science.gov (United States)

    van der Geest, Ivana M M; Darlington, Anne-Sophie E; Streng, Isabelle C; Michiels, Erna M C; Pieters, Rob; van den Heuvel-Eibrink, Marry M

    2014-06-01

    Approximately 25% of children diagnosed with cancer eventually die. Losing a child puts parents at increased risk for developing psychological problems. To explore parents' perceptions of the interaction with health care professionals (communication, continuity of care, and parental involvement) and symptom management during the pediatric palliative phase, and to investigate the influence on long-term grief in parents who lost a child to cancer. A total of 89 parents of 57 children who died of cancer between 2000 and 2004 participated in this retrospective cross-sectional study by completing a set of questionnaires measuring grief (Inventory of Traumatic Grief), parents' perceptions of the interaction with health care professionals (communication, continuity of care, and parental involvement), and symptom management during the palliative phase. Care was assessed on a five point Likert scale (1=disagree and 5=agree). Parents highly rated communication (4.6±0.6), continuity of care (4.3±0.6), and parental involvement (4.6±0.7) during the palliative phase. Parents' most often reported physical and psychological symptoms of their child during the palliative phase were fatigue (75%), pain (74%), anxiety to be alone (52%), and anger (48%). Higher ratings of parents on communication (β=-9.08, P=0.03) and continuity of care (β=-11.74, P=0.01) were associated with lower levels of long-term parental grief. The severity of the child's dyspnea (β=2.96, P=0.05), anxiety to be alone (β=4.52, Pparental grief. Multivariate models combining the interaction with health care professionals and symptom management showed a significant influence of both aspects on long-term parental grief. Both interaction with health care professionals, especially communication and continuity of care, and symptom management in children dying of cancer are associated with long-term parental grief levels. Copyright © 2014 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights

  5. Long-term Impact of Prevention Programs to Promote Effective Parenting: Lasting Effects but Uncertain Processes

    OpenAIRE

    Sandler, Irwin; Schoenfelder, Erin; Wolchik, Sharlene; MacKinnon, David

    2011-01-01

    This chapter reviews findings from 46 randomized experimental trials of preventive parenting interventions. The findings of these trials provide evidence of effects to prevent a wide range of problem outcomes and to promote competencies from one to twenty years later. However, there is a paucity of evidence concerning the processes that account for program effects. Three alternative pathways are proposed as a framework for future research on the long-term effects of preventive parenting progr...

  6. Impact of delirium on postoperative frailty and long term cardiovascular events after cardiac surgery

    OpenAIRE

    Ogawa, Masato; Izawa, Kazuhiro P.; Satomi-Kobayashi, Seimi; Tsuboi, Yasunori; Komaki, Kodai; Gotake, Yasuko; Sakai, Yoshitada; Tanaka, Hiroshi; Okita, Yutaka

    2017-01-01

    Background Postoperative delirium (POD) is a common and critical complication after cardiac surgery. However, the relationship between POD and postoperative physical frailty and the effect of both on long-term clinical outcomes have not been fully explored. Objective We aimed to examine the associations among POD, postoperative frailty, and major adverse cardiac events (MACE). Design This was a prospective cohort study. Methods We studied 329 consecutive patients undergoing elective cardiac s...

  7. The Impact of Fiscal Deficit on Long-term Nominal Interest Rate in Nepal

    OpenAIRE

    Rajendra Pandit

    2005-01-01

    Growth of debt stock, changes in the debt composition, ownership structure of government debt and movement of interest rate on debt have been observed since the very beginning in Nepal. Public debt issues have been more and more market oriented and secondary market activities for short-term securities have expanded in recent years. Presently, the amount of debt service payment which exerts pressure on government budget constitutes more than one fourth of the total government expenditure. The ...

  8. The potential impact of urban growth simulation on the long-term planning of our cities

    CSIR Research Space (South Africa)

    Waldeck, L

    2012-10-01

    Full Text Available of urban growth simulation on the long-term planning of our cities 4th Biennial Conference Presented by: Dr Louis Waldeck Date: 10 October 2012 Slide 2 of 17 Why Urban Growth Simulation? ? Reduced carbon footprint ? Reduce resource consumption... of the population concentrated in cities and the opportunities to gain efficiencies, cities are the most important arena for intervention.? Maurice Strong Unabated urbanisation Quest for sustainable development What makes a city sustainable? Slide 3 of 17...

  9. Impact of Short-Term Treatment with Telmisartan on Cerebral Arterial Remodeling in SHR

    OpenAIRE

    Foulquier , Sébastien; Lartaud , Isabelle; Dupuis , François

    2014-01-01

    International audience; Background and Purpose: Chronic hypertension decreases internal diameter of cerebral arteries and arterioles. We recently showed that short-term treatment with the angiotensin II receptor blocker telmisartan restored baseline internal diameter of small cerebral arterioles in spontaneously hypertensive rats (SHR), via reversal of structural remodeling and inhibition of the angiotensin II vasoconstrictor response. As larger arteries also participate in the regulation of ...

  10. Impact of process variations and long term degradation on 6T-SRAM cells

    Directory of Open Access Journals (Sweden)

    Th. Fischer

    2007-06-01

    Full Text Available In modern deep-submicron CMOS technologies voltage scaling can not keep up with the scaling of the dimensions of transistors. Therefore the electrical fields inside the transistors are not constant anymore, while scaling down the device area. The rising electrical fields bring up reliability problems, such as hot carrier injection. Also other long term degradation mechanisms like Negative Bias Temperature Instability (NBTI come into the focus of circuit design.

    Along with process device parameter variations (threshold voltage, mobility, variations due to the degradation of devices form a big challenge for designers to build circuits that both yield high under the influence of process variations and remain functional with respect to long term device drift.

    In this work we present the influence of long term degradation and process variations on the performance of SRAM core-cells and parametric yield of SRAM arrays. For different use cases we show the performance degradation depending on temperature and supply voltage.

  11. Impact of short-term treatment with telmisartan on cerebral arterial remodeling in SHR.

    Directory of Open Access Journals (Sweden)

    Sébastien Foulquier

    Full Text Available Chronic hypertension decreases internal diameter of cerebral arteries and arterioles. We recently showed that short-term treatment with the angiotensin II receptor blocker telmisartan restored baseline internal diameter of small cerebral arterioles in spontaneously hypertensive rats (SHR, via reversal of structural remodeling and inhibition of the angiotensin II vasoconstrictor response. As larger arteries also participate in the regulation of cerebral circulation, we evaluated whether similar short-term treatment affects middle cerebral arteries of SHR.Baseline internal diameters of pressurised middle cerebral arteries from SHR and their respective controls, Wistar Kyoto rats (WKY and responses to angiotensin II were studied in a small vessel arteriograph. Pressure myogenic curves and passive internal diameters were measured following EDTA deactivation, and elastic modulus from stress-strain relationships.Active baseline internal diameter was 23% lower in SHR compared to WKY, passive internal diameter (EDTA 28% lower and elastic modulus unchanged. Pressure myogenic curves were shifted to higher pressure values in SHR. Telmisartan lowered blood pressure but had no effect on baseline internal diameter nor on structural remodeling (passive internal diameter and elastic modulus remained unchanged compared to SHR. Telmisartan shifted the pressure myogenic curve to lower pressure values than SHR.In the middle cerebral arteries of SHR, short-term treatment with telmisartan had no effect on structural remodeling and did not restore baseline internal diameter, but allowed myogenic tone to adapt towards lower pressure values.

  12. Sixth Africa malaria day in 2006: how far have we come after the Abuja Declaration?

    Directory of Open Access Journals (Sweden)

    Wanga Charles L

    2006-11-01

    Full Text Available Abstract Each year on the 25th April Africa and the rest of the world commemorate Africa Malaria Day as was agreed upon at the African Summit on Roll Back Malaria held in Abuja, Nigeria on 25th April 2000. The summit also called upon the United Nations to declare the period 2001–2010 a decade for malaria. The 1st Africa Malaria Day was commemorated with the theme "Communities Play a Central Role in Tackling Malaria". The 6th Africa Malaria Day was observed in 2006 with the theme "Get Your ACT Together" and the slogan "Universal Access to Effective Malaria Treatment is a Human Right". This article by the Secretariat of the Multilateral Initiative on Malaria (MIM was also part of the commemorations for the day. MIM was founded in 1997 as an alliance of institutions and individuals concerned with the malaria problem, and aiming at maximizing the impact of scientific research on malaria through strengthening African research capacity and coordinated global collaboration. The MIM Secretariat has been hosted in rotation by the founding institutions, and is being hosted for the first time in Africa by the African Malaria Network Trust (AMANET in Dar es Salaam, Tanzania. This article reviews the malaria situation in Africa six years after the Abuja Declaration, highlighting the disease burden trends, failures, achievements, challenges, and the way forward.

  13. Normative foundations of technology transfer and transnational benefit principles in the UNESCO Universal Declaration on Bioethics and Human Rights.

    Science.gov (United States)

    Faunce, Thomas Alured; Nasu, Hitoshi

    2009-06-01

    The United Nations Scientific, Education, and Cultural Organization Universal Declaration on Bioethics and Human Rights (UDBHR) expresses in its title and substance a controversial linkage of two normative systems: international human rights law and bioethics. The UDBHR has the status of what is known as a "nonbinding" declaration under public international law. The UDBHR's foundation within bioethics (and association, e.g., with virtue-based or principlist bioethical theories) is more problematic. Nonetheless, the UDBHR contains socially important principles of technology transfer and transnational benefit (articles 14, 15, and 21). This paper is one of the first to explore how the disciplines of bioethics and international human rights law may interact in the UDBHR to advance the policy relevance and health impact of such principles. It investigates their normative ancestry in the UDBHR, as well as relevant conceptual differences between bioethics and public international law in this respect, and how these may be relevant to their conceptual evolution and application.

  14. Novelty-Sensitive Dopaminergic Neurons in the Human Substantia Nigra Predict Success of Declarative Memory Formation.

    Science.gov (United States)

    Kamiński, Jan; Mamelak, Adam N; Birch, Kurtis; Mosher, Clayton P; Tagliati, Michele; Rutishauser, Ueli

    2018-04-12

    The encoding of information into long-term declarative memory is facilitated by dopamine. This process depends on hippocampal novelty signals, but it remains unknown how midbrain dopaminergic neurons are modulated by declarative-memory-based information. We recorded individual substantia nigra (SN) neurons and cortical field potentials in human patients performing a recognition memory task. We found that 25% of SN neurons were modulated by stimulus novelty. Extracellular waveform shape and anatomical location indicated that these memory-selective neurons were putatively dopaminergic. The responses of memory-selective neurons appeared 527 ms after stimulus onset, changed after a single trial, and were indicative of recognition accuracy. SN neurons phase locked to frontal cortical theta-frequency oscillations, and the extent of this coordination predicted successful memory formation. These data reveal that dopaminergic neurons in the human SN are modulated by memory signals and demonstrate a progression of information flow in the hippocampal-basal ganglia-frontal cortex loop for memory encoding. Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  15. The short-term impacts of a cyclone on seagrass communities in Southwest Madagascar

    Science.gov (United States)

    Côté-Laurin, Marie-Claude; Benbow, Sophie; Erzini, Karim

    2017-04-01

    Cyclones are large-scale disturbances with highly destructive potential in coastal ecosystems. On February 22, 2013, a powerful tropical cyclone made landfall on the southwest coast of Madagascar, a region which is infrequently hit by such extreme weather events coming from the Mozambique Channel. Seagrass ecosystems, which provide valuable ecosystems services to local communities, are especially vulnerable because they thrive in shallow waters. The impact of Cyclone Haruna on seagrass diversity, height and coverage and associated fish diversity, abundance and biomass was assessed in 3 sites near Andavadoaka (22°07‧S, 43°23‧E) before and after the event using fish underwater visual census, video-transects, and seagrass quadrats. The cyclone caused a significant loss in seagrass cover at all 3 sites. Thalassia hemprichii and Syringodium isoetifolium were the most affected species. Andavadoaka beach, the most exposed site, which was also subject to human use and was most fragmented, suffered the largest negative effects of the cyclone. Cyclone Haruna was not found to significantly affect fish assemblages, which are highly mobile organisms able to use a diversity of niches and adjacent habitats after seagrass fragmentation. Extensive sampling and longer time-scale studies would be needed to fully evaluate the cyclone impact on communities of seagrass and fish, and track potential recovery in seagrass coverage. The intensity and destructive potential of cyclones is expected to increase with global warming, which is of concern for developing countries that encompass most of the world's seagrass beds. This study provided a unique and key opportunity to monitor immediate impacts of an extreme disturbance in a region where cyclones rarely hit coastal ecosystems and where local populations remain highly dependent on seagrass meadows.

  16. Long Term Environment and Economic Impacts of Coal Liquefaction in China

    Energy Technology Data Exchange (ETDEWEB)

    Fletcher, Jerald [West Virginia Univ., Morgantown, WV (United States)

    2014-03-31

    The project currently is composed of six specific tasks – three research tasks, two outreach and training tasks, and one project management and communications task. Task 1 addresses project management and communication. Research activities focused on Task 2 (Describe and Quantify the Economic Impacts and Implications of the Development and Deployment of Coal-to-Liquid Facilities in China), Task 3 (Development of Alternative Coal Gasification Database), and Task 4 (Geologic Carbon Management Options). There also were significant activities related to Task 5 (US-China Communication, Collaboration, and Training on Clean Coal Technologies) as well as planning activity performed in support of Task 6 (Training Programs).

  17. The long-term fiscal impact of funding cuts to Danish public fertility clinics

    DEFF Research Database (Denmark)

    Connolly, Mark P; Postma, Maarten J; Crespi, Simone

    2011-01-01

    This study evaluated the fiscal impact attributed to recent policy changes that limited funding to public fertility clinics in Denmark. Taking into consideration that introducing patient co-payments will influence the numbers of couples treated, the number of children born every year from assisted...... reproductive technology will be affected. To reflect the government perspective, the model assessed the average life course of a cohort of assisted-conception singletons taking into consideration age-specific, per-capita government transfers (e.g. education, health care, family allowances, education, pensions...

  18. The long-term fiscal impact of funding cuts to Danish public fertility clinics

    DEFF Research Database (Denmark)

    Connolly, Mark P; Postma, Maarten J; Crespi, Simone

    2011-01-01

    reproductive technology will be affected. To reflect the government perspective, the model assessed the average life course of a cohort of assisted-conception singletons taking into consideration age-specific, per-capita government transfers (e.g. education, health care, family allowances, education, pensions......This study evaluated the fiscal impact attributed to recent policy changes that limited funding to public fertility clinics in Denmark. Taking into consideration that introducing patient co-payments will influence the numbers of couples treated, the number of children born every year from assisted...

  19. Long-term exposure to slightly elevated air temperature alleviates the negative impacts of short term waterlogging stress by altering nitrogen metabolism in cotton leaves.

    Science.gov (United States)

    Wang, Haimiao; Chen, Yinglong; Xu, Bingjie; Hu, Wei; Snider, John L; Meng, Yali; Chen, Binglin; Wang, Youhua; Zhao, Wenqing; Wang, Shanshan; Zhou, Zhiguo

    2018-02-01

    Short-term waterlogging and chronic elevated temperature occur frequently in the Yangtze River Valley, yet the effects of these co-occurring environments on nitrogen metabolism of the subtending leaf (a major source leaf for boll development) have received little attention. In this study, plants were exposed to two temperature regimes (31.6/26.5 °C and 34.1/29.0 °C) and waterlogging events (0 d, 3 d, 6 d) during flowering and boll development. The results showed that the effects of waterlogging stress and elevated temperature in isolation on nitrogen metabolism were quite different. Waterlogging stress not only limited NR (EC 1.6.6.1) and GS (EC 6.3.1.2) activities through the down-regulation of GhNR and GhGS expression for amino acid synthesis, but also promoted protein degradation by enhanced protease activity and peptidase activity, leading to lower organ and total biomass (reduced by 12.01%-27.63%), whereas elevated temperature inhibited protein degradation by limited protease activity and peptidase activity, promoting plant biomass accumulation. Furthermore, 2-3 °C chronic elevated temperature alleviated the negative impacts of a brief (3 d) waterlogging stress on cotton leaves, with the expression of GhNiR up-regulated, the activities of NR, GS and GOGAT (EC 1.4.7.1) increased and the activities of protease and peptidase decreased, leading to higher protein concentration and enhanced leaf biomass for EW 3 relative to AW 3 . The results of the study suggested that exposure to slightly elevated air temperature improves the cotton plants' ability to recover from short-term (3 d) waterlogging stress by sustaining processes associated with nitrogen assimilation. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  20. Short-term impacts of air pollutants in Switzerland: Preliminary scenario calculations for selected Swiss energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Andreani-Aksoyoglu, S; Keller, J [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1999-08-01

    In the frame of the comprehensive assessment of Swiss energy systems, air quality simulations were performed by using a 3-dimensional photo-chemical dispersion model. The objective is to investigate the impacts of pollutants in Switzerland for future options of Swiss energy systems. Four scenarios were investigated: Base Case: simulations with the projected emissions for the year 2030, Scenario 1) all nuclear power plants were replaced by oil-driven combined cycle plants (CCP), Scenarios 2 to 4) traffic emissions were reduced in whole Switzerland as well as in the cities and on the highways separately. Changes in the pollutant concentrations and depositions, and the possible short-term impacts are discussed on the basis of exceedences of critical levels for plants and limits given to protect the public health. (author) 2 figs., 7 refs.

  1. Short-term impact evaluation of a social marketing campaign to prevent syphilis among men who have sex with men.

    Science.gov (United States)

    Darrow, William W; Biersteker, Susan

    2008-02-01

    We carried out an independent short-term impact evaluation of a social marketing campaign designed to reduce syphilis infections among men who have sex with men in south Florida in 2004. Venue-based surveys were conducted shortly after the campaign began and 6 months later to assess changes in exposure to campaign materials, awareness, knowledge about syphilis, perceptions of risk, sexual behavior, clinic visits, and testing and treatment for syphilis among participants. Exposure to social marketing campaign materials increased from 18.0% at baseline to 36.5% at follow-up (Pcampaign objectives were fully met. The interventions were insufficient to produce a significant impact among men who have sex with men in south Florida.

  2. Using indirect methods to understand the impact of forced migration on long-term under-five mortality.

    Science.gov (United States)

    Singh, Kavita; Karunakara, Unni; Burnham, Gilbert; Hill, Kenneth

    2005-11-01

    Despite the large numbers of displaced persons and the often-lengthy periods of displacement, little is known about the impact of forced migration on long-term under-five mortality. This paper looks at the Brass Method (and adaptations of this method) and the Preceding Birth Technique in combination with a classification of women by their migration and reproductive histories, in order to study the impact of forced migration on under-five mortality. Data came from the Demography of Forced Migration Project, a study on mortality, fertility and violence in the refugee and host populations of Arua District, Uganda and Yei River District, Sudan. Results indicate that women who did not migrate in a situation of conflict and women who repatriated before the age of 15, had children with the highest under-five mortality rates compared with women who were currently refugees and women who repatriated after the age of 15.

  3. Impact of long-term corticosteroid therapy on the distribution pattern of lower limb atherosclerosis.

    Science.gov (United States)

    Willenberg, T; Diehm, N; Zwahlen, M; Kalka, C; Do, D-D; Gretener, S; Ortmann, J; Baumgartner, I

    2010-04-01

    Ectopic calcification and mediacalcinosis can be promoted by corticosteroid use. Aim of the present investigation is to describe macrovascular disease features in patients with long-term corticosteroid therapy and symptomatic lower limb peripheral arterial occlusive disease (PAD). A consecutive series of 2783 patients undergoing clinical and angiographic work-up of PAD were screened for long-term (>5 years) corticosteroid use (group A). Comparison was performed to a randomly selected age-, sex- and risk factor-matched PAD control cohort from the same series without corticosteroid use (group B). Patients with diabetes mellitus or severe renal failure were excluded. Arterial calcification was evaluated by qualitative assessment on radiographic images. Severity of atherosclerotic lesions was analysed from angiographic images using a semi-quantitative score (Bollinger score). In general, 12 patients (5 males, mean age 78.5 +/- 9.0 years) with 15 ischaemic limbs qualified to be enrolled in group A and were compared to 23 matching control patients (6 2 males, mean age 79.5 +/- 6 years) with 32 ischaemic limbs. Incompressibility of ankle arteries determined by measurement of the ankle-brachial index was seen in 12 limbs (80%) in group A compared to 3 limbs (9%) in group B (p = 0.0009). No significant difference was found comparing group A and B for segmental calcification, whereas comparison of the atherosclerotic burden using the angiographic severity score showed a significantly higher score at the infragenicular arterial level in group A (p = 0.001). Findings suggest that the long-term corticosteroid therapy is associated with a distally accentuated, calcifying peripheral atherosclerosis inducing arterial incompressibility. This occlusion pattern is comparable to patients with renal failure or diabetes. Further research is required to support our observations.

  4. Investigation of whether various types of radioactive waste are equivalent in terms of the radiological impact associated with their disposal

    International Nuclear Information System (INIS)

    Fearn, H.S.; Smith, G.M.; Davis, J.P.; Hill, M.D.

    1989-01-01

    The aim of this study is to investigate the possibility that various types of waste are equivalent in terms of the risks associated with their disposal in so far as they are viewed by different sections of society. If such a framework can be established it could be used as an aid to decisions as to whether central disposal facilities, to accept waste from several countries, should be constructed. Details are presented of assumed radionuclide inventories for a representative range of radioactive wastes, calculations and results of the radiological impacts of their disposal, and illustrative methods for weighting the various components of impact which when summed provide an overall measure of impact. Five sets of weighting factors have been devised which are intended to represent the views of a) the radiological protection community, b) those with a pro-nuclear industry view, c) those who oppose nuclear power on safety grounds, d) the inhabitants of the country receiving wastes for disposal, and e) the inhabitants of the country dispatching wastes. On the basis of the calculated weighted radiological impacts it is demonstrated how conclusions can be drawn about general views on the disposal of each waste, about likely attitudes to the export of wastes from one country for disposal in another, and attitudes to exchanging wastes between countries. The study is preliminary and of limited scope. However, the results show that the general methodology is practicable and could be applied in a wider ranging investigation

  5. Combined Impacts of Medium Term Socio-Economic Changes and Climate Change on Water Resources in a Managed Mediterranean Catchment

    Directory of Open Access Journals (Sweden)

    Anastassi Stefanova

    2015-04-01

    Full Text Available Climate projections agree on a dryer and warmer future for the Mediterranean. Consequently, the region is likely to face serious problems regarding water availability and quality in the future. We investigated potential climate change impacts, alone (for three scenario periods and in combination with four socio-economic scenarios (for the near future on water resources in a Mediterranean catchment, whose economy relies on irrigated agriculture and tourism. For that, the Soil and Water Integrated Model (SWIM was applied to the drainage area of the Mar Menor coastal lagoon, using a set of 15 climate scenarios and different land use maps and management settings. We assessed the long-term average seasonal and annual changes in generated runoff, groundwater recharge and actual evapotranspiration in the catchment, as well as on water inflow and nutrients input to the lagoon. The projected average annual changes in precipitation are small for the first scenario period, and so are the simulated impacts on all investigated components, on average. The negative trend of potential climate change impacts on water resources (i.e., decrease in all analyzed components becomes pronounced in the second and third scenario periods. The applied socio-economic scenarios intensify, reduce or even reverse the climate-induced impacts, depending on the assumed land use and management changes.

  6. The Impact of the Term Auction Facility on the Liquidity Risk Premium and Unsecured Interbank Spreads

    OpenAIRE

    Syrstad, Olav

    2014-01-01

    This paper investigates the effectiveness of the Federal Reserve's Term Auction Facility (TAF) in alleviating the liquidity shortage in USD and reducing the spread between the 3-month Libor rate and the expected policy rate. I construct a proxy for the 3-month liquidity risk premium based on data from the FX forward market which enables me to (i) decompose the Libor spread into a liquidity premium and a credit premium, and (ii) test the effectiveness of the TAF in reducing the liquidity premi...

  7. Predicted environmental impacts of long-term waste management at the Savannah River Site

    International Nuclear Information System (INIS)

    Topp, S.V.

    1979-01-01

    This paper describes the different alternative approaches to long-term waste management at SRP, along with their probable relative costs, risks, and uncertainties; the issue of methodology for decision-making in nuclear waste management is also raised. This paper contains a preliminary listing of the SRP alternaties including a simple cost-risk analysis. The alternatives are: glass shipped offsite to Federal repository; air-cooled vault with glass at SRP; liquid waste slurry stored in SRP bedrock cavern; and continued tank farm operation with salt and sludge

  8. Electron-impact excitation-autoionization in the cadmium isoelectronic sequence: A case of target term dependence in scattering theory

    International Nuclear Information System (INIS)

    Pindzola, M.S.; Griffin, D.C.; Bottcher, C.

    1983-01-01

    Excitation-autoionization contributions to electron-impact ionization are calculated for several atomic ions in the cadmium isoelectronic sequence. We calculate excitation cross sections in the distorted-wave approximation and compare them in one case to a calculation in the close-coupling approximation. We focus attention on the 4d 10 5s 2 →4d 9 5s 2 nf inner-shell excitations in In + , Sb 3+ , and Xe 6+ . Hartree-Fock atomic structure calculations for the 4d 9 5s 2 nf configurations are found to be highly term dependent. Thus our predictions for the total ionization cross section from the 5s subshell for these ions exhibit strong target term dependence. Our Xe 6+ results are found to be in excellent agreement with the recent experimental crossed-beam measurements of Gregory and Crandall

  9. Mitigation of short-term disturbance negative impacts in the agent-based model of a production companies network

    Science.gov (United States)

    Shevchuk, G. K.; Berg, D. B.; Zvereva, O. M.; Medvedeva, M. A.

    2017-11-01

    This article is devoted to the study of a supply chain disturbance impact on manufacturing volumes in a production system network. Each network agent's product can be used as a resource by other system agents (manufacturers). A supply chain disturbance can lead to operating cease of the entire network. Authors suggest using of short-term partial resources reservation to mitigate negative consequences of such disturbances. An agent-based model with a reservation algorithm compatible with strategies for resource procurement in terms of financial constraints was engineered. This model works in accordance with the static input-output Leontief 's model. The results can be used for choosing the ways of system's stability improving, and protecting it from various disturbances and imbalance.

  10. Risk-adjusted impact of administrative costs on the distribution of terminal wealth for long-term investment.

    Science.gov (United States)

    Guillén, Montserrat; Jarner, Søren Fiig; Nielsen, Jens Perch; Pérez-Marín, Ana M

    2014-01-01

    The impact of administrative costs on the distribution of terminal wealth is approximated using a simple formula applicable to many investment situations. We show that the reduction in median returns attributable to administrative fees is usually at least twice the amount of the administrative costs charged for most investment funds, when considering a risk-adjustment correction over a reasonably long-term time horizon. The example we present covers a number of standard cases and can be applied to passive investments, mutual funds, and hedge funds. Our results show investors the potential losses they face in performance due to administrative costs.

  11. Perioperative hyperoxia - Long-term impact on cardiovascular complications after abdominal surgery, a post hoc analysis of the PROXI trial

    DEFF Research Database (Denmark)

    Fonnes, Siv; Gogenur, Ismail; Sondergaard, Edith Smed

    2016-01-01

    BACKGROUND: Increased long-term mortality was found in patients exposed to perioperative hyperoxia in the PROXI trial, where patients undergoing laparotomy were randomised to 80% versus 30% oxygen during and after surgery. This post hoc follow-up study assessed the impact of perioperative hyperoxia...... included myocardial infarction, other heart disease, and acute coronary syndrome or death. Data were analysed in the Cox proportional hazards model. RESULTS: The primary outcome, acute coronary syndrome, occurred in 2.5% versus 1.3% in the 80% versus 30% oxygen group; HR 2.15 (95% CI 0.96-4.84). Patients...

  12. The effect of long-term impact of elevated temperature on changes in the microstructure of inconel 740H alloy

    Directory of Open Access Journals (Sweden)

    M. Sroka

    2017-01-01

    Full Text Available This paper presents the results of investigations on microstructure changes after the long-term impact of temperature. The microstructure investigations were carried out by light microscopy and scanning electron microscopy. The qualitative and quantitative identification of the existing precipitates was carried out using X-ray phase composition analysis. The effect of elevated temperature on precipitation processes of test material were described. The obtained results of investigations form part of the material characteristics of new-generation alloys, which can be indirectly associated with the stability of functional properties under the simultaneous effect of high temperature and stress.

  13. Long-term genetic monitoring of a riverine dragonfly, Orthetrum coerulescens (Odonata: Libellulidae]: Direct anthropogenic impact versus climate change effects.

    Science.gov (United States)

    Herzog, Rebecca; Hadrys, Heike

    2017-01-01

    Modern conservationists call for long term genetic monitoring datasets to evaluate and understand the impact of human activities on natural ecosystems and species on a global but also local scale. However, long-term monitoring datasets are still rare but in high demand to correctly identify, evaluate and respond to environmental changes. In the presented study, a population of the riverine dragonfly, Orthetrum coerulescens (Odonata: Libellulidae), was monitored over a time period from 1989 to 2013. Study site was an artificial irrigation ditch in one of the last European stone steppes and "nature heritage", the Crau in Southern France. This artificial riverine habitat has an unusual high diversity of odonate species, prominent indicators for evaluating freshwater habitats. A clearing of the canal and destruction of the bank vegetation in 1996 was assumed to have great negative impact on the odonate larval and adult populations. Two mitochondrial markers (CO1 & ND1) and a panel of nuclear microsatellite loci were used to assess the genetic diversity. Over time they revealed a dramatic decline in diversity parameters between the years 2004 and 2007, however not between 1996 and 1997. From 2007 onwards the population shows a stabilizing trend but has not reached the amount of genetic variation found at the beginning of this survey. This decline cannot be referred to the clearing of the canal or any other direct anthropogenic impact. Instead, it is most likely that the populations' decay was due to by extreme weather conditions during the specific years. A severe drought was recorded for the summer months of these years, leading to reduced water levels in the canal causing also other water parameters to change, and therefore impacting temperature sensitive riverine habitat specialists like the O. coerulescens in a significant way. The data provide important insights into population genetic dynamics and metrics not always congruent with traditional monitoring data (e

  14. Impact of the components of Mediterranean nutrition regimen on long-term prognosis of diabetic patients with coronary artery disease

    Directory of Open Access Journals (Sweden)

    Soheila Mosharraf

    2013-11-01

    Full Text Available BACKGROUND: The impact of different nutritional regimens on long-term prognosis and outcome in diabetic patients with coronary artery disease (CAD has been questioned. Therefore, the objective of the present study was to determine the effects of different nutritional components of Mediterranean regimen on long-term cardiovascular events in diabetic patients with CAD in the Iranian population. METHODS: In a prospective cohort study, we recruited 233 consecutive patients with the diagnosis of type 2 diabetes mellitus and with at least 6 months of documented CAD. Nutritional assessment was obtained by a validated semi-quantitative food frequency questionnaire (FFQ and the diet score was calculated on the basis of the Mediterranean diet quality index (Med-DQI. For Assessing long-term CAD prognosis, the patients were followed by telephone for one year. The study endpoint was long-term major adverse cardiac and cerebrovascular event (MACCE. RESULTS: Death was observed in 19 patients (8.2% during the one-year follow-up. Two patients (0.9% suffered non-fatal myocardial infarction and 14 (6.0% needed revascularization within 1 year after discharge from hospital. Overall MACCE within one year in the study population was 12.4%. There were significant differences between number of deaths and dietary scores of saturated fatty acid, cholesterol, meats, fish, and fruit and vegetables (P < 0.05. Moreover, significant differences were found between MACCE rate and dietary scores of saturated fatty acid, cholesterol, and fruit and vegetables (P < 0.05. Using multivariate logistic regression models, Mediterranean dietary regimen could effectively predict long-term death as well as MACCE adjusted for gender and age variables. CONCLUSION: Mediterranean dietary regimens, including low level of cholesterol and saturated fatty acid, can effectively improve long-term outcome including death and MACCE in diabetic patients with CAD.   Keywords: Diabetes Mellitus, Coronary

  15. Cognitive impact after short-term exposure to different proton pump inhibitors: assessment using CANTAB software.

    Science.gov (United States)

    Akter, Sanjida; Hassan, Md Rajib; Shahriar, Mohammad; Akter, Nahia; Abbas, Md Golam; Bhuiyan, Mohiuddin Ahmed

    2015-12-27

    Studies have shown that proton pump inhibitors (PPIs) increase the brain burden of amyloid-beta (Aβ) and also create vitamin B12 deficiency. However, these two phenomena have deleterious effect on cognition and Alzheimer's disease (AD). Since the use of PPIs has increased tremendously for the last few years, it is of great public health importance to investigate the cognitive impact of PPIs. Hence, the purpose of this study was to investigate the degree of neuropsychological association of each PPI with different cognitive functions. Sixty volunteers of either gender were recruited and divided randomly into six groups: five test groups for five classes of PPIs and one control group. All the groups participated in the five computerized neuropsychological tests (nine subtests) of the Cambridge Neuropsychological Test Automated Battery twice: at the beginning of the study and 7 days thereafter. We found statistically and clinically significant impairment in visual memory, attention, executive function, and working and planning function. One-way analysis of variance findings showed that all PPIs had a similar negative impact on cognition. However, paired-samples t tests indicated that omeprazole showed significant (p benefits of prescribing these medications. A study done for a longer period of time with a larger sample size might yield better results.

  16. The impact of long term exposure to phthalic acid esters on reproduction in Chinese rare minnow (Gobiocypris rarus)

    International Nuclear Information System (INIS)

    Guo, Yongyong; Yang, Yuanjin; Gao, Yong; Wang, Xianfeng; Zhou, Bingsheng

    2015-01-01

    The environmental risk of phthalic acid esters (PAEs) is of great concern. We investigated the reproductive impairment of di-(2-ethylhexyl)-phthalate (DEHP) on Chinese rare minnow, an endemic fish inhabiting the upper streams of the Yangtze River. Chinese rare minnow larvae were exposed to environmentally relevant concentrations of DEHP (0, 4.2, 13.3, and 40.8 μg/L) for 6 months. Plasma testosterone and 17β-estradiol levels decreased in females, accompanied by downregulation of cyp19a and cyp17 gene transcription in ovary. Increases in plasma testosterone concentration were observed in males, accompanied by downregulation of cyp19a gene transcription in testes. Hepatic VTG gene transcription was upregulated in males and females. Exposure to DEHP reduced egg production and inhibited oocyte maturation in females and retarded spermiation in males. Decreased egg protein content was measured in F1 embryos. These results indicate that long-term exposure to low concentrations of DEHP (13.3 μg/L) causes endocrine disruption and impairs fish reproduction. - Highlights: • PAEs in the aquatic environment may pose risk to endemic fish species. • Long-term exposure to DEHP affected sex hormone levels in rare minnow. • DEHP affected gonad development. • Long-term exposure caused reduction of fecundity, but not sex ratio. • Environmentally relevant concentrations of DEHP impair fish reproduction. - Long-term exposure to low concentrations of DEHP adversely impact Chinese rare minnow reproduction

  17. Impacts of Near-Term Climate Change on Irrigation Demands and Crop Yields in the Columbia River Basin

    Science.gov (United States)

    Rajagopalan, K.; Chinnayakanahalli, K. J.; Stockle, C. O.; Nelson, R. L.; Kruger, C. E.; Brady, M. P.; Malek, K.; Dinesh, S. T.; Barber, M. E.; Hamlet, A. F.; Yorgey, G. G.; Adam, J. C.

    2018-03-01

    Adaptation to a changing climate is critical to address future global food and water security challenges. While these challenges are global, successful adaptation strategies are often generated at regional scales; therefore, regional-scale studies are critical to inform adaptation decision making. While climate change affects both water supply and demand, water demand is relatively understudied, especially at regional scales. The goal of this work is to address this gap, and characterize the direct impacts of near-term (for the 2030s) climate change and elevated CO2 levels on regional-scale crop yields and irrigation demands for the Columbia River basin (CRB). This question is addressed through a coupled crop-hydrology model that accounts for site-specific and crop-specific characteristics that control regional-scale response to climate change. The overall near-term outlook for agricultural production in the CRB is largely positive, with yield increases for most crops and small overall increases in irrigation demand. However, there are crop-specific and location-specific negative impacts as well, and the aggregate regional response of irrigation demands to climate change is highly sensitive to the spatial crop mix. Low-value pasture/hay varieties of crops—typically not considered in climate change assessments—play a significant role in determining the regional response of irrigation demands to climate change, and thus cannot be overlooked. While, the overall near-term outlook for agriculture in the region is largely positive, there may be potential for a negative outlook further into the future, and it is important to consider this in long-term planning.

  18. Simulated biomass, environmental impacts and best management practices for long-term switchgrass systems in a semi-arid region

    International Nuclear Information System (INIS)

    Wang, Limei; Qian, Yaling; Brummer, Joe E.; Zheng, Jiyong; Wilhelm, Sarah; Parton, William J.

    2015-01-01

    Long-term information on switchgrass (Panicum virgatum L.) as a biomass energy crop grown on marginally saline soil and the associated impacts on soil carbon (C) and nitrogen (N) dynamics, greenhouse gas (GHG) emissions, and best management practices (BMPs) are limited. In this study, we employed the DAYCENT model, based on a 4-year switchgrass field experiment, to evaluate the long-term biomass yield potential and environmental impacts, and further to develop BMPs for switchgrass in a semi-arid region. The model showed that long-term (14-year) annual mean biomass yields were 9.6 and 5.2 Mg ha −1 for irrigated and rainfed switchgrass systems, respectively. The simulated biomass yields correlated well with field-measured biomass with r 2 values of 0.99 and 0.89 for irrigated and rainfed systems, respectively. Soil organic carbon (SOC) and soil total nitrogen (STN) accumulated rapidly after switchgrass establishment, with mean accrual rates of 0.99–1.13 Mg C ha −1  yr −1 and 0.04–0.08 Mg N ha −1  yr −1 , respectively. Based on the outputs of numerous long-term model simulations with variable irrigation water supplies and N rates, the irrigation regime and N rate with the highest yield to input ratio were chosen as BMPs. The DAYCENT model predicted-BMP was irrigating every 14 days at 70% potential evapotranspiration combined with an N rate of 67 kg ha −1  yr −1 . Switchgrass established and produced biomass reasonably well in this semi-arid region; however, appropriate irrigation and N fertilization were needed for optimal biomass yield. Switchgrass had a great potential to sequester C into soils with low N 2 O emissions while supplying significant quantities of biomass for biofuel synthesis. - Highlights: • The DAYCENT model reliably simulated the growth of switchgrass on marginal land. • Long-term biomass and environmental impacts were simulated using the DAYCENT model. • Switchgrass produced biomass well on marginal land, but

  19. Functional Gain After Inpatient Stroke Rehabilitation: Correlates and Impact on Long-Term Survival.

    Science.gov (United States)

    Scrutinio, Domenico; Monitillo, Vincenzo; Guida, Pietro; Nardulli, Roberto; Multari, Vincenzo; Monitillo, Francesco; Calabrese, Gianluigi; Fiore, Pietro

    2015-10-01

    Prediction of functional outcome after stroke rehabilitation (SR) is a growing field of interest. The association between SR and survival still remains elusive. We sought to investigate the factors associated with functional outcome after SR and whether the magnitude of functional improvement achieved with rehabilitation is associated with long-term mortality risk. The study population consisted of 722 patients admitted for SR within 90 days of stroke onset, with an admission functional independence measure (FIM) score of stroke onset to rehabilitation admission (PStroke Scale score at rehabilitation admission (P<0.001), and aphasia (P=0.021) were independently associated with FIM gain. The R2 of the model was 0.275. During a median follow-up of 6.17 years, 36.9% of the patients died. At multivariable Cox analysis, age (P<0.0001), coronary heart disease (P=0.018), atrial fibrillation (P=0.042), total cholesterol (P=0.015), and total FIM gain (P<0.0001) were independently associated with mortality. The adjusted hazard ratio for death significantly decreased across tertiles of increasing FIM gain. Several factors are independently associated with functional gain after SR. Our findings strongly suggest that the magnitude of functional improvement is a powerful predictor of long-term mortality in patients admitted for SR. © 2015 American Heart Association, Inc.

  20. Impact of Short-Term Training Camp on Aortic Blood Pressure in Collegiate Endurance Runners

    Directory of Open Access Journals (Sweden)

    Tsubasa Tomoto

    2018-03-01

    Full Text Available To investigate the influence of short-term vigorous endurance training on aortic blood pressure (BP, pulse wave analysis was performed in 36 highly trained elite collegiate endurance runners before and after a 7-day intense training camp. Subjects participated three training sessions per day, which mainly consisted of long distance running and sprint training to reach the daily target distance of 26 km. After the camp, they were divided into two groups based on whether the target training was achieved. Aortic systolic BP, pulse pressure, and tension-time index (TTI, a surrogate index of the myocardial oxygen demand were significantly elevated after the camp in the accomplished group but not in the unaccomplished group, whereas the brachial BP remained unchanged in both groups. The average daily training distance was significantly correlated with the changes in aortic systolic BP (r = 0.608, p = 0.0002, pulse pressure (r = 0.415, p = 0.016, and TTI (r = 0.438, p = 0.011. These results suggest that aortic BP is affected by a short-term vigorous training camp even in highly trained elite endurance athletes presumably due to a greater training volume compared to usual.

  1. Impact of long term Yoga practice on sleep quality and quality of life in the elderly

    Directory of Open Access Journals (Sweden)

    Mangesh A Bankar

    2013-01-01

    Full Text Available Background: Sleep disturbances and decline in the physical functionality are common conditions associated with aging. Pharmacological treatment of sleep disturbances can be associated with various adverse effects. Short term trials of Yoga on sleep have shown beneficial effects. Objectives: To evaluate the effect of long-term Yoga exercises on sleep quality and quality of life (QOL in the elderly. Materials and Methods: This was a cross-sectional study in which data were collected from elderly people aged 60 years or more living in Nagpur city. We employed two types of survey questionnaires: Pittsburgh sleep quality index (PSQI and QOL Leiden-Padua (LEIPAD Questionnaire. A total of 65 elderly men and women who signed an informed consent and completed questionnaires were included in the study. Sleep quality score PSQI and QOL (LEIPAD Questionnaire score of the study group were evaluated and compared with the control group using Mann-Whitney U test. Results: Total PSQI score in Yoga group was lower than that of the control group. Also various QOL scores of the Yoga groups were higher than the control group. Conclusion: Addition of regular Yoga exercises in the daily routine of elderly people can help to achieve good sleep quality as well as improve the QOL.

  2. The impact of interference on short-term memory for visual orientation.

    Science.gov (United States)

    Rademaker, Rosanne L; Bloem, Ilona M; De Weerd, Peter; Sack, Alexander T

    2015-12-01

    Visual short-term memory serves as an efficient buffer for maintaining no longer directly accessible information. How robust are visual memories against interference? Memory for simple visual features has proven vulnerable to distractors containing conflicting information along the relevant stimulus dimension, leading to the idea that interacting feature-specific channels at an early stage of visual processing support memory for simple visual features. Here we showed that memory for a single randomly orientated grating was susceptible to interference from a to-be-ignored distractor grating presented midway through a 3-s delay period. Memory for the initially presented orientation became noisier when it differed from the distractor orientation, and response distributions were shifted toward the distractor orientation (by ∼3°). Interestingly, when the distractor was rendered task-relevant by making it a second memory target, memory for both retained orientations showed reduced reliability as a function of increased orientation differences between them. However, the degree to which responses to the first grating shifted toward the orientation of the task-relevant second grating was much reduced. Finally, using a dichoptic display, we demonstrated that these systematic biases caused by a consciously perceived distractor disappeared once the distractor was presented outside of participants' awareness. Together, our results show that visual short-term memory for orientation can be systematically biased by interfering information that is consciously perceived. (c) 2015 APA, all rights reserved).

  3. Long term microparticle impact fluxes on LDEF determined from optical survey of Interplanetary Dust Experiment (IDE) sensors

    Science.gov (United States)

    Simon, C. G.; Oliver, J. P.; Cooke, W. J.; Downey, K. I.; Kassel, P. C.

    1995-01-01

    Many of the IDE metal-oxide-silicon (MOS) capacitor-discharge impact sensors remained active during the entire Long Duration Exposure Facility (LDEF) mission. An optical survey of impact sites on the active surfaces of these sensors has been extended to include all sensors from the low-flux sides of LDEF (i.e. the west or trailing side, the earth end, and the space end) and 5-7 active sensors from each LDEF's high-flux sides (i.e. the east or leading side, the south side, and the north side). This survey was facilitated by the presence of a relatively large (greater than 50 micron diameter) optical signature associated with each impact site on the active sensor surfaces. Of the approximately 4700 impacts in the optical survey data set, 84% were from particles in the 0.5 to 3 micron size range. An estimate of the total number of hypervelocity impacts on LDEF from particles greater than 0.5 micron diameter yields a value of approximately 7 x 10(exp 6). Impact feature dimensions for several dozen large craters on MOS sensors and germanium witness plates are also presented. Impact fluxes calculated from the IDE survey data closely matched surveys of similar size impacts (greater than or equal to 3 micron diameter craters in Al, or marginal penetrations of a 2.4 micron thick Al foil) by other LDEF investigators. Since the first year IDE data were electronically recorded, the flux data could be divided into three long term time periods: the first year, the entire 5.8 year mission, and the intervening 4.8 years (by difference). The IDE data show that there was an order of magnitude decrease in the long term microparticle impact flux on the trailing side of LDEF, from 1.01 to 0.098 x 10(exp -4) m(exp 2)/s, from the first year in orbit compared to years 2-6. The long term flux on the leading edge showed an increase from 8.6 to 11.2 x 10(exp -4) m(exp -2)/s over this same time period. (Short term flux increases up to 10,000 times the background rate were recorded on the

  4. On the Impact of a Quadratic Acceleration Term in the Analysis of Position Time Series

    Science.gov (United States)

    Bogusz, Janusz; Klos, Anna; Bos, Machiel Simon; Hunegnaw, Addisu; Teferle, Felix Norman

    2016-04-01

    The analysis of Global Navigation Satellite System (GNSS) position time series generally assumes that each of the coordinate component series is described by the sum of a linear rate (velocity) and various periodic terms. The residuals, the deviations between the fitted model and the observations, are then a measure of the epoch-to-epoch scatter and have been used for the analysis of the stochastic character (noise) of the time series. Often the parameters of interest in GNSS position time series are the velocities and their associated uncertainties, which have to be determined with the highest reliability. It is clear that not all GNSS position time series follow this simple linear behaviour. Therefore, we have added an acceleration term in the form of a quadratic polynomial function to the model in order to better describe the non-linear motion in the position time series. This non-linear motion could be a response to purely geophysical processes, for example, elastic rebound of the Earth's crust due to ice mass loss in Greenland, artefacts due to deficiencies in bias mitigation models, for example, of the GNSS satellite and receiver antenna phase centres, or any combination thereof. In this study we have simulated 20 time series with different stochastic characteristics such as white, flicker or random walk noise of length of 23 years. The noise amplitude was assumed at 1 mm/y-/4. Then, we added the deterministic part consisting of a linear trend of 20 mm/y (that represents the averaged horizontal velocity) and accelerations ranging from minus 0.6 to plus 0.6 mm/y2. For all these data we estimated the noise parameters with Maximum Likelihood Estimation (MLE) using the Hector software package without taken into account the non-linear term. In this way we set the benchmark to then investigate how the noise properties and velocity uncertainty may be affected by any un-modelled, non-linear term. The velocities and their uncertainties versus the accelerations for

  5. Long-term impacts of college sexual assaults on women survivors' educational and career attainments.

    Science.gov (United States)

    Potter, Sharyn; Howard, Rebecca; Murphy, Sharon; Moynihan, Mary M

    2018-02-15

    To examine the well-documented mental and physical health problems suffered by undergraduate women sexually assaulted while on campus with an exploration of how the trauma impacts a survivor's lifetime education trajectory and career attainment. In November and December 2015, researchers recruited US participants using an online crowdsourcing tool and a Listserv for sexual violence prevention and response professionals. Of 316 women who completed initial screening, 89 qualified to complete a Qualtrics survey. Eighty-one participants completed the online survey, and 32 participated in phone interviews. Ninety-one percent of the participants reported health problems related to the assault that they attributed to difficulties they faced in their attainment of their education and career goals. The findings suggest the importance of simultaneously examining the effects of human capital losses and mental and physical health problems attributed to the costly public health problem of campus sexual assault.

  6. The impact of short-term stochastic variability in solar irradiance on optimal microgrid design

    Energy Technology Data Exchange (ETDEWEB)

    Schittekatte, Tim [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Pontificia Comillas Univ., Madrid (Spain); Florence School of Regulation, Firenze (Italy); Stadler, Michael [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Center for Energy Innovation Technologies, Hofamt Priel (Austria); Cardoso, Gonçalo [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Mashayekh, Salman [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Narayanan, Sankar [Microgrid Labs, Cary, NC (United States)

    2016-07-01

    This paper proposes a new methodology to capture the impact of fast moving clouds on utility power demand charges observed in microgrids with photovoltaic (PV) arrays, generators, and electrochemical energy storage. It consists of a statistical approach to introduce sub-hourly events in the hourly economic accounting process. The methodology is implemented in the Distributed Energy Resources Customer Adoption Model (DER-CAM), a state of the art mixed integer linear model used to optimally size DER in decentralized energy systems. Results suggest that previous iterations of DER-CAM could undersize battery capacities. The improved model depicts more accurately the economic value of PV as well as the synergistic benefits of pairing PV with storage.

  7. The Impact of Fundamental and Financial Traders on the Term Structure of Oil

    DEFF Research Database (Denmark)

    Heidorn, Thomas; Mokinski, Frieder; Rühl, Christof

    2015-01-01

    We study how the exposure of fundamental and financial traders affects the futures curve of WTI oil and the market integration between WTI and Brent measured by their price spread. To obtain a parsimonious representation of the futures curve, we decompose it into a level-, a slope- and a curvature...... factor in a first step. In a second step, we separately regress each extracted factor on measures of the market exposure of fundamental and financial traders revealing whether and how the exposure of the two trader groups affects the different dimensions of the futures curve. Spanning from 2006 until...... 2012, our dataset covers sub-periods of a sharp WTI-price rise as well as a diverging Brent-WTI-spread. Our contribution is threefold: First, we suggest that it is important to distinguish between level and slope as we find that fundamental traders have a measurable impact on the level of the futures...

  8. Nitrate addition has minimal short-term impacts on greenland ice sheet supraglacial prokaryotes

    DEFF Research Database (Denmark)

    Cameron, Karen A.; Stibal, Marek; Chrismas, Nathan

    2017-01-01

    Tropospheric nitrate levels are predicted to increase throughout the 21st century, with potential effects on terrestrial ecosystems, including the Greenland ice sheet (GrIS). This study considers the impacts of elevated nitrate concentrations on the abundance and composition of dominant bulk...... and active prokaryotic communities sampled from in situ nitrate fertilization plots on the GrIS surface. Nitrate concentrations were successfully elevated within sediment-filled meltwater pools, known as cryoconite holes; however, nitrate additions applied to surface ice did not persist. Estimated bulk...... cryoconite communities were not nitrate limited at the time of sampling. Instead, temporal changes in biomass and community composition were more pronounced. As these in situ incubations were short (6 weeks), and the community composition across GrIS surface ice is highly variable, we suggest that further...

  9. Impact of long-term diesel contamination on soil microbial community structure

    DEFF Research Database (Denmark)

    Sutton, Nora; Maphosa, Farai; Morillo, Jose

    2013-01-01

    Microbial community composition and diversity at a diesel-contaminated railway site were investigated by pyrosequencing of bacterial and archaeal 16S rRNA gene fragments to understand the interrelationships among microbial community composition, pollution level, and soil geochemical and physical...... properties. To this end, 26 soil samples from four matrix types with various geochemical characteristics and contaminant concentrations were investigated. The presence of diesel contamination significantly impacted microbial community composition and diversity, regardless of the soil matrix type. Clean...... observed in contaminated samples. Redundancy analysis indicated that increased relative abundances of the phyla Chloroflexi, Firmicutes, and Euryarchaeota correlated with the presence of contamination. Shifts in the chemical composition of diesel constituents across the site and the abundance of specific...

  10. Potential long-term impacts of changes in US vehicle fuel efficiency standards

    International Nuclear Information System (INIS)

    Bezdek, Roger H.; Wendling, Robert M.

    2005-01-01

    Changes in corporate average fuel economy (CAFE) standards have not been made due, in part, to concerns over their negative impact on the economy and jobs. This paper simulates the effects of enhanced CAFE standards through 2030 and finds that such changes could increase GDP and create 300,000 jobs distributed widely across states, industries, and occupations. In addition, enhanced CAFE standards could, each year, reduce US oil consumption by 30 billion gallons, save drivers $40 billion, and reduce US greenhouse gas emissions by 100 million tons. However, there is no free lunch. There would be widespread job displacement within many industries, occupations, and states, and increased CAFE standards require that fuel economy be given priority over other vehicle improvements, increase the purchase price of vehicles, require manufacturers to produce vehicles that they otherwise would not, and require consumers to purchase vehicles that would not exist except for CAFE

  11. Long-Term Health Impact of Early Nutrition: The Power of Programming.

    Science.gov (United States)

    Koletzko, Berthold; Brands, Brigitte; Grote, Veit; Kirchberg, Franca F; Prell, Christine; Rzehak, Peter; Uhl, Olaf; Weber, Martina

    2017-01-01

    The Power of Programming conference 2016 at Ludwig-Maximilians-Universität Munich brought together about 600 researchers and other stakeholders from around the world who reviewed the recent evidence on the lasting health impact of environment and nutrition during early life, from pre-pregnancy to early childhood. The conference was hosted by the Early Nutrition Project, a multidisciplinary research collaboration funded by the European Commission with collaborating researchers from 35 institutions in 15 countries in Europe, the United States and Australia. The project explores the early origins of obesity, adiposity and associated non-communicable diseases, underlying mechanisms and opportunities for prevention. The project also proactively supports translational application of research findings. In fact, some existing evidence has already been rapidly adopted into policy, regulatory standards and practice. Further, broad dissemination of findings is achieved through the established digital eLearning platform of the Early Nutrition eAcademy, video clip-based learning and graphically supported messaging to consumers. The project demonstrated powerful effects of early metabolic programming on later health. Compared to other common prevention strategies, modifying risk trajectories in early life can achieve a much larger risk reduction and be more cost-effective. While some effective prevention strategies have been promptly implemented in policy and guidelines, legislation and practice, in other areas, the uptake is limited by a paucity of quality human intervention trials and insufficient evaluation of the feasibility of implementation and econometric impact. This needs to be strengthened by future collaborative research work. © 2017 S. Karger AG, Basel.

  12. Long-term climate change impacts on agricultural productivity in eastern China

    Energy Technology Data Exchange (ETDEWEB)

    Chavas, Daniel R.; Izaurralde, Roberto C.; Thomson, Allison M.; Gao, Xuejie

    2009-06-15

    Increasing atmospheric greenhouse gas concentrations are expected to induce significant climate change over the next century and beyond, but the impacts on society remain highly uncertain. This work examines potential climate change impacts on the productivity of five major crops in northeastern China: canola, corn, potato, rice, and winter wheat. In addition to determining domain-wide trends, the objective is to identify vulnerable and emergent regions under future climate conditions, defined as having a greater than 10% decrease and increase in productivity, respectively. Data from the ICTP RegCM3 regional climate model for baseline (1961-1990) and future (2071-2100) periods under A2 scenario conditions are used as input in the EPIC agro-ecosystem simulation model in the domain [30ºN, 108ºE] to [42ºN, 123ºE]. Simulations are performed with and without the enhanced CO2 fertilization effect. Results indicate that aggregate potential productivity (i.e. if the crop is grown everywhere) increases 6.5% for rice, 8.3% for canola, 18.6% for corn, 22.9% for potato, and 24.9% for winter wheat, although with significant spatial variability for each crop. However, absent the enhanced CO2 fertilization effect, potential productivity declines in all cases ranging from 2.5-12%. Interannual yield variability remains constant or declines in all cases except rice. Climate variables are found to be more significant drivers of simulated yield changes than changes in soil properties, except in the case of potato production in the northwest where the effects of wind erosion are more significant. Overall, in the future period corn and winter wheat benefit significantly in the North China Plain, rice remains dominant in the southeast and emerges in the northeast, potato and corn yields become viable in the northwest, and potato yields suffer in the southwest with no other crop emerging as a clear beneficiary from among those simulated in this study.

  13. Preliminary evaluation of aircraft impact on a near term nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Frano, R. Lo, E-mail: rosa.lofrano@ing.unipi.it [Department of Mechanical, Nuclear and Production Engineering, University of PISA, L.go L. Lazzarino 2, via Diotisalvi, no. 2-56126 Pisa (Italy); Forasassi, G. [Department of Mechanical, Nuclear and Production Engineering, University of PISA, L.go L. Lazzarino 2, via Diotisalvi, no. 2-56126 Pisa (Italy)

    2011-12-15

    Highlights: Black-Right-Pointing-Pointer The effects of military/civilian airplanes crash in a NPP were evaluated. Black-Right-Pointing-Pointer We adequately simulated the global response and safety margin of an SMR reactor. Black-Right-Pointing-Pointer The analyses allowed to represent the progressive failure/damaging processes. Black-Right-Pointing-Pointer The outer containment seemed to suffer some localized penetration and spalling. Black-Right-Pointing-Pointer The results highlighted the plant integrity is ensured despite the impact damages. - Abstract: For the assessment of the safety and durability of a nuclear power plant (NPP), the containment building behaviour shall be evaluated, under various service and extreme conditions, both natural or produced by natural accident or vicious man activities, like September 2001 jet aircraft crashes. The aim of this paper is to preliminary evaluate the effects and consequences of the energy transmitted to the outer containment walls (according to the international safety and design code guidelines, as NRC or IAEA ones) due to a military or civil aircraft impact into a nuclear plant, considered as a 'beyond design basis' event. To perform reliable analysis of such a large-scale structure and determine the structural effects of the propagation of this types of impulsive loads (response of containment structure), a realistic but still feasible numerical model with suitable materials characteristics were used by means of which relevant physical phenomena are reflected. Moreover a sensitivity analysis has also been carried out considering the effects of different containment wall thickness and reinforced/prestressed concrete features. The obtained results were analysed to check the NPP containment strength margins.

  14. Long-term impact of war on healthcare costs: an eight-country study.

    Directory of Open Access Journals (Sweden)

    Ramon Sabes-Figuera

    Full Text Available Exposure to war can negatively affect health and may impact on healthcare costs. Estimating these costs and identifying their predictors is important for appropriate service planning. We aimed to measure use of health services in an adult population who had experienced war in the former-Yugoslavia on average 8 years previously, and to identify characteristics associated with the use and costs of healthcare.War-affected community samples in Bosnia-Herzegovina, Croatia, Kosovo, FYR Macedonia, and Serbia were recruited through a random walk technique. Refugees in Germany, Italy and the UK were contacted through registers, organisations and networking. Current service use was measured for the previous three months and combined with unit costs for each country for the year 2006/7. A two-part approach was used, to identify predictors of service use with a multiple logistic regression model and predictors of cost with a generalised linear regression model.3,313 participants were interviewed in Balkan countries and 854 refugees in Western European countries. In the Balkan countries, traumatic events and mental health status were related to greater service use while in Western countries these associations were not found. Participants in Balkan countries with post traumatic stress disorder (PTSD had costs that were 63% higher (p = 0.005 than those without PTSD. Distress experienced during the most traumatic war event was associated with higher costs (p = 0.013. In Western European countries costs were 76% higher if non-PTSD anxiety disorders were present (0.027 and 63% higher for mood disorders (p = 0.006.War experiences and their effects on mental health are associated with increased health care costs even many years later, especially for those who stayed in the area of conflict. Focussing on the mental health impact of war is important for many reasons including those of an economic nature.

  15. Herbivore Impact on Tundra Plant Community Dynamics Using Long-term Remote Sensing Observation

    Science.gov (United States)

    Yu, Q.; Engstrom, R.; Shiklomanov, N. I.

    2014-12-01

    Arctic tundra biome is now experiencing dramatic environmental changes accentuated by summer sea-ice decline, permafrost thaw, and shrub expansion. Multi-decadal time-series of the Normalized Difference Vegetation Index (NDVI, a spectral metric of vegetation productivity) shows an overall "greening" trend across the Arctic tundra biome. Regional trends in climate plausibly explain large-scale patterns of increasing plant productivity, as diminished summer sea-ice extent warms the adjacent land causing tundra vegetation to respond positively (increased photosynthetic aboveground biomass). However, at more local scales, there is a great deal of spatial variability in NDVI trends that likely reflects differences in hydrology and soil conditions, disturbance history, and use by wildlife and humans. Particularly, habitat use by large herbivores, such as reindeer and caribou, has large impacts on vegetation dynamics at local and regional scales, but the role of herbivores in modulating the response of vegetation to warming climate has received little attention. This study investigates regional tundra plant community dynamics within inhabits of different sizes of wild caribou/reindeer herds across the Arctic using GIMMS NDVI (Normalized Difference Vegetation Index) 3g data product. The Taimyr herd in Russia is one of the largest herds in the world with a population increase from 450,000 in 1975 to about 1 million animals in 2000. The population of the porcupine caribou herd has fluctuated in the past three decades between 100,000 and 180,000. Time-series of the maximum NDVI within the inhabit area of the Taimyr herd has increased about 2% per decade over the past three decades, while within the inhabit area of the Porcupine herd the maximum NDVI has increased about 5% per decade. Our results indicate that the impact of large herbivores can be detected from space and further analyses on seasonal dynamics of vegetation indices and herbivore behavior may provide more

  16. The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice

    Science.gov (United States)

    Lai, Hoang M.; Aronow, Wilbert S.; Mercando, Anthony D.; Kalen, Phoenix; Desai, Harit V.; Gandhi, Kaushang; Sharma, Mala; Amin, Harshad; Lai, Trung M.

    2011-01-01

    Summary Background Statins reduce coronary events in patients with coronary artery disease. Material/Methods Chart reviews were performed in 305 patients (217 men and 88 women, mean age 74 years) not treated with statins during the first year of being seen in an outpatient cardiology practice but subsequently treated with statins. Based on the starting date of statins use, the long-term outcomes of myocardial infarction (MI), percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABGS) before and after statin use were compared. Results Mean follow-up was 65 months before statins use and 66 months after statins use. MI occurred in 31 of 305 patients (10%) before statins, and in 13 of 305 patients (4%) after statins (pcardiology practice reduces the incidence of MI, PCI, and CABGS. PMID:22129898

  17. Impact of Open-Market Share Repurchases on Long-Term Stock Returns

    Directory of Open Access Journals (Sweden)

    Mohamed Albaity

    2016-10-01

    Full Text Available After the Asian financial crisis in 1997, firms listed on Bursa Malaysia were allowed to repurchase their shares on the open market. The number of companies engaged in share buyback is increasing and has become a tool to stabilize price by signaling undervaluation of the share. However, studies on share buyback in Malaysia are limited to the price performance surrounding the buyback events. This study aims to fill this gap by examining long-run price performance after the actual share buyback event over a sampling period of 2 years from 2009 to 2010 for Malaysian firms listed on FTSE Bursa Malaysia. There is no evidence to conclude that there exist long-term abnormal returns using the calendar-time portfolio approach that support the inefficient market hypothesis. On the contrary, buy-and-hold method was found to be significant supporting that the Malaysian stock market is semi-strong efficient.

  18. [Violent video games and aggression: long-term impact and selection effects].

    Science.gov (United States)

    Staude-Müller, Frithjof

    2011-01-01

    This study applied social-cognitive models of aggression in order to examine relations between video game use and aggressive tendencies and biases in social information processing. To this end, 499 secondary school students (aged 12-16) completed a survey on two occasions one year apart. Hierarchical regression analysis probed media effects and selection effects and included relevant contextual variables (parental monitoring of media consumption, impulsivity, and victimization). Results revealed that it was not the consumption of violent video games but rather an uncontrolled pattern of video game use that was associated with increasing aggressive tendencies. This increase was partly mediated by a hostile attribution bias in social information processing. The influence of aggressive tendencies on later video game consumption was also examined (selection path). Adolescents with aggressive traits intensified their video game behavior only in terms of their uncontrolled video game use. This was found even after controlling for sensation seeking and parental media control.

  19. Impacts of neonicotinoid use on long-term population changes in wild bees in England

    Science.gov (United States)

    Woodcock, Ben A.; Isaac, Nicholas J. B.; Bullock, James M.; Roy, David B.; Garthwaite, David G.; Crowe, Andrew; Pywell, Richard F.

    2016-08-01

    Wild bee declines have been ascribed in part to neonicotinoid insecticides. While short-term laboratory studies on commercially bred species (principally honeybees and bumblebees) have identified sub-lethal effects, there is no strong evidence linking these insecticides to losses of the majority of wild bee species. We relate 18 years of UK national wild bee distribution data for 62 species to amounts of neonicotinoid use in oilseed rape. Using a multi-species dynamic Bayesian occupancy analysis, we find evidence of increased population extinction rates in response to neonicotinoid seed treatment use on oilseed rape. Species foraging on oilseed rape benefit from the cover of this crop, but were on average three times more negatively affected by exposure to neonicotinoids than non-crop foragers. Our results suggest that sub-lethal effects of neonicotinoids could scale up to cause losses of bee biodiversity. Restrictions on neonicotinoid use may reduce population declines.

  20. Long-term multifactorial climate change impacts on mesofaunal biomass and nitrogen content

    DEFF Research Database (Denmark)

    Madsen, Mette Vestergård; Dyrnum, Kristine; Michelsen, Anders

    2015-01-01

    increased at elevated CO2, or tended do so. In contrast, enchytraeid N content decreased at elevated CO2. Soil microbial biomass N pool and litter C:N ratio also increased with elevated CO2, which suggests that mite biomasses are more coupled to microbial biomass, whereas enchytraeid biomass to a larger...... extent is governed by litter nitrogen concentration, i.e. litter quality. Structural equation modelling confirmed the positive coupling between soil microbial N content and oribatid biomass and further between oribatid and mesostigmatic biomass. The SEM also revealed a negative relationship between...... microbial N content and enchytraeid biomass. The biomass of all mesofaunal groups was reduced by spring drought, especially when combined with warming. Enchytraeid and especially collembolan biomass suffered greater drought declines than mite biomasses. We conclude that under long-term elevated CO2 exposure...

  1. Impact of type 1 diabetes on maternal long-term risk of hospitalisation and mortality

    DEFF Research Database (Denmark)

    Knorr, Sine; Juul, Svend; Bytoft, Birgitte

    2018-01-01

    AIMS/HYPOTHESIS: The aims of this study were to examine long-term mortality and morbidity rates in mothers with type 1 diabetes, both overall and according to the level of albuminuria prior to pregnancy, the presence of hypertension, pre-eclampsia and periconceptional HbA1c. METHODS: This study...... was a part of the EPICOM (Environmental Versus Genetic and Epigenetic Influences on Growth, Metabolism and Cognitive Function in Offspring of Mothers with Type 1 Diabetes) study, which is a prospective follow-up study focusing on pregnancies complicated by maternal type 1 diabetes. We carried out...... a nationwide combined clinical and register-based cohort study of mortality rates and hospital admissions in mothers with diabetes (n = 986) who gave birth between 1992 and 2000. Control mothers (n = 91,441) were women from the background population, matched according to age and year of childbirth. Age...

  2. Long-Term Fertilization Impacts on Soil Fertility and Resources Use

    DEFF Research Database (Denmark)

    van der Bom, Frederik Johannes T

    the nutrient contents. Finally, plants that are better at taking up P from the soil under limiting conditions could play an important role in improving sustainability, but experiments with modern cereal varieties suggest that modern breeding has resulted in varieties with rather similar ability for P uptake...... nutrient inputs from synthetic fertilisers and animal manure, and variable soil fertility conditions, affect growth, productivity, and resilience of cereal crops, and examined the effects on soil phosphorus pools and soil microbial communities. The study included 20 year year of experimental field data......, new field experimentation and lab and green-house trials with soils from the Long-Term Nutrient Depletion Trial at the KU experimental farm in Taastrup, Denmark. The field was purposely depleted of nutrients for 30 years before the introduction of different permanent nutrient application treatments...

  3. Impact of long term pesticide usage on soil microbial activities and 14C-monocrotophos degradation

    International Nuclear Information System (INIS)

    Tayaputch, N.; Pimpan, P.; Phaikaew, Y.; Chukiatwatana, L.

    2001-01-01

    The effects of long term pesticide usage on soil microbial activities and degradation of 14 C-monocrotophos was observed under cotton field conditions. The experimental field was divided into treated and untreated plots. Pesticides were applied to treated plots at weekly intervals as in common practice in Thailand. The total numbers of applications were 11, 16 and 16 for first, second and third crop seasons, during the three years from 1996 to 1998. Soil samples at depths of 0-15 cm and 15-30 cm were sampled before and after pesticide application for the first two crops, while in the third crop season only the surface layer of soil was taken. The samples were assessed for CO 2 from respiration, soil microbial population, iron reduction capacity, and rates of nitrification. Soil biomass and microbial activities as measured from respiration and iron reduction decreased in the treated plots at both depths after each pesticide application over the three crop seasons, whereas samples from untreated plots at both depths did not show decreases. Repeated application of pesticides did not show any effect on nitrification rates of the first crop but there was inhibition in the second and third crops. Soil columns, treated with 14 C-monocrotophos one week after last pesticide application, were harvested after 0, 3, 6, 9, 18, 24 and 30 months. Extractable residues of 14 C were found only in the 0-15 cm layer. In treated and untreated plots, residues declined from 80.17 and 85.68 to 0.44% of the applied 14 C within 6 months. The long term usage of pesticides did not affect the half-life of 14 C-monocrotophos. Bound residues of 14 C were found at the highest concentrations, 18.94 and 12.58% of that applied, at 6 months in treated and untreated plots, thereafter the binding decreased to 4.68 and 2.74% within 30 months. (author)

  4. Impact of purchasing the CPAP device on acceptance and long-term adherence: a Belgian model.

    Science.gov (United States)

    Leemans, Joke; Rodenstein, Daniel; Bousata, Jamila; Mwenge, Gimbada Benny

    2018-02-01

    In Belgium, patients with moderate to severe OSA (AHI > 20) who show less than 30 micro-arousals per hour slept (MAI) cannot benefit from CPAP refund by the social security (SS). To assess the influence of reimbursement on CPAP acceptance, and long-term adherence. OSA patients (AHI > 20) were included regardless of MAI. All patients were offered a CPAP trial of 3-5 days for habituation. Two groups were defined and compared: «Out of pocket money» patients (OOP) with MAI < 30 that were invited to purchase their device and «reimbursed group» that were offered a CPAP reimbursed by the social security. 812 patients were found: 59 in the OOP group, mostly females, sleepier and using more hypnotics. Out of the reimbursed group, 183 patients were matched to the OOP patients on the grounds of age, AHI and BMI. 90% of OOP and 94% of reimbursed patients (p 0.379) accepted a CPAP trial; 74% of OOP and 90% of reimbursed patients acquired a CPAP device (p 0.005) thereafter, whereas 82% and, respectively, 84% of those (p 0.254) were still on CPAP after a mean follow-up of 711 and 604 days with a mean ± SD daily compliance of 5.3 ± 3 and 6.1 ± 2 h, respectively (p 0.159). Only fatigue scale seems to influence the purchase of CPAP by OOP patients. CPAP reimbursement influences the purchase of CPAP but once the device becomes available there is no difference with reimbursed patients in long-term adherence.

  5. Long term neurocognitive impact of low dose prenatal methylmercury exposure in Hong Kong.

    Science.gov (United States)

    Lam, Hugh Simon; Kwok, Ka Ming; Chan, Peggy Hiu Ying; So, Hung Kwan; Li, Albert Martin; Ng, Pak Cheung; Fok, Tai Fai

    2013-04-01

    International studies suggest that low dose prenatal methylmercury exposure (>29 nmol/L) has long-term adverse neurocognitive effects. There is evidence that the majority of children in Hong Kong exceed this level as a result of high fish consumption of mothers during pregnancy. To study whether there are any associations between low-dose prenatal methylmercury exposure and neurocognitive outcomes in Hong Kong children. All 1057 children from the original birth cohort were eligible for entry into the study, except children with conditions that would affect neurocognitive development, but were unrelated to methylmercury exposure. Subjects were assessed by a wide panel of tests covering a broad range of neurocognitive functions: Hong Kong Wechsler Intelligence Scale for Children (HK-WISC), Hong Kong List Learning Test (HKLLT), Tests of Everyday Attention for Children (TEACH), Boston Naming Test, and Grooved Pegboard Test. 608 subjects were recruited (median age 8.2 years, IQR 7.3, 8.8; 53.9% boys). After correction by confounders including child age and sex, multivariate analysis showed that cord blood mercury concentration was significantly associated with three subtests: Picture Arrangement of HK-WISC (coefficient -0.944, P=0.049) and Short and Long Delay Recall Difference of the HKLLT (coefficient -1.087, P=0.007 and coefficient -1.161, P=0.005, respectively), i.e., performance worsened with increasing prenatal methylmercury exposure in these subtests. Small, but statistically significant adverse associations between prenatal methylmercury exposure and long-term neurocognitive effects (a visual sequencing task and retention ability of verbal memory) were found in our study. These effects are compatible with findings of studies with higher prenatal methylmercury exposure levels and suggest that safe strategies to further reduce exposure levels in Hong Kong are desirable. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Exposure to clothianidin seed-treated canola has no long-term impact on honey bees.

    Science.gov (United States)

    Cutler, G Christopher; Scott-Dupree, Cynthia D

    2007-06-01

    We conducted a long-term investigation to ascertain effects on honey bee, Apis mellifera L., colonies during and after exposure to flowering canola, Brassica napus variety Hyola 420, grown from clothianidin-treated seed. Colonies were placed in the middle of 1-ha clothianidin seed-treated or control canola fields for 3 wk during bloom, and thereafter they were moved to a fall apiary. There were four treated and four control fields, and four colonies per field, giving 32 colonies total. Bee mortality, worker longevity, and brood development were regularly assessed in each colony for 130 d from initial exposure to canola. Samples of honey, beeswax, pollen, and nectar were regularly collected for 130 d, and the samples were analyzed for clothianidin residues by using high-performance liquid chromatography with tandem mass spectrometry detection. Overall, no differences in bee mortality, worker longevity, or brood development occurred between control and treatment groups throughout the study. Weight gains of and honey yields from colonies in treated fields were not significantly different from those in control fields. Although clothianidin residues were detected in honey, nectar, and pollen from colonies in clothianidin-treated fields, maximum concentrations detected were 8- to 22-fold below the reported no observable adverse effects concentration. Clothianidin residues were not detected in any beeswax sample. Assessment of overwintered colonies in spring found no differences in those originally exposed to treated or control canola. The results show that honey bee colonies will, in the long-term, be unaffected by exposure to clothianidin seed-treated canola.

  7. Modelling impacts of atmospheric deposition and temperature on long-term DOC trends.

    Science.gov (United States)

    Sawicka, K; Rowe, E C; Evans, C D; Monteith, D T; E I Vanguelova; Wade, A J; J M Clark

    2017-02-01

    It is increasingly recognised that widespread and substantial increases in Dissolved organic carbon (DOC) concentrations in remote surface, and soil, waters in recent decades are linked to declining acid deposition. Effects of rising pH and declining ionic strength on DOC solubility have been proposed as potential dominant mechanisms. However, since DOC in these systems is derived mainly from recently-fixed carbon, and since organic matter decomposition rates are considered sensitive to temperature, uncertainty persists over the extent to which other drivers that could influence DOC production. Such potential drivers include fertilisation by nitrogen (N) and global warming. We therefore ran the dynamic soil chemistry model MADOC for a range of UK soils, for which time series data are available, to consider the likely relative importance of decreased deposition of sulphate and chloride, accumulation of reactive N, and higher temperatures, on soil DOC production in different soils. Modelled patterns of DOC change generally agreed favourably with measurements collated over 10-20years, but differed markedly between sites. While the acidifying effect of sulphur deposition appeared to be the predominant control on the observed soil water DOC trends in all the soils considered other than a blanket peat, the model suggested that over the long term, the effects of nitrogen deposition on N-limited soils may have been sufficient to raise the "acid recovery DOC baseline" significantly. In contrast, reductions in non-marine chloride deposition and effects of long term warming appeared to have been relatively unimportant. The suggestion that future DOC concentrations might exceed preindustrial levels as a consequence of nitrogen pollution has important implications for drinking water catchment management and the setting and pursuit of appropriate restoration targets, but findings still require validation from reliable centennial-scale proxy records, such as those being developed

  8. Long-term impact after fulminant Guillain-Barré syndrome, case report and literature review

    Directory of Open Access Journals (Sweden)

    Rougé A

    2016-11-01

    Full Text Available Alain Rougé,1,2 Jérémie Lemarié,1,2 Sébastien Gibot,1,2 Pierre Edouard Bollaert1,2 1Medical Intensive Care Unit, Hôpital Central, University Hospital of Nancy, Nancy, France; 2INSERM UMRS-1116, Faculty of Medicine, University of Lorraine, Nancy, France Abstract: A 47-year-old man was admitted to the intensive care unit a few hours after ­presenting to emergency department with acute diplopia and dysphonia. Swallowing disorders and respiratory muscular weakness quickly required invasive ventilation. On day 3, the patient was in a “brain-death”-like state with deep coma and absent brainstem reflexes. Electroencephalogram ruled out brain death diagnosis as a paradoxical sleep trace was recorded. Cerebrospinal fluid analysis, electrophysiologic studies, and a recent history of diarrhea led to the diagnosis of Campylobacter jejuni-related fulminant Guillain-Barré syndrome (GBS mimicking brain death. The outcome was favorable after long Intensive Care Unit and inpatient rehabilitation stays, despite persistent disability at 9 years follow-up. This case and the associated literature review of 34 previously reported fulminant GBS patients emphasize the importance of electrophysiological investigations during clinical brain-death states with no definite cause. Fulminant GBS has a worse outcome than “standard” GBS with higher rates of severe disability (about 50%. Long-term physiotherapy and specific rehabilitation programs appear essential to improve recovery. Keywords: fulminant Guillain-Barré syndrome, brain death, electroencephalogram, C. jejuni, long-term follow 

  9. Fishing in dangerous waters: Remarks on a controversial appeal to spawner-recruit theory for long-term impact assessment

    International Nuclear Information System (INIS)

    Fletcher, R.I.; Deriso, R.B.

    1988-01-01

    In the Hudson River power plant case, the defending utility companies appealed to the practices of commercial fishery managers as precedent for their own uses of spawner-recruit models in forecasting the effects on stock abundances of long-term water withdrawals by the power plants. In contrast to this perception of spawner-recruit models as commonly accepted instruments of fishery management, the present survey of managers and regulatory agencies revealed instead a universal rejection of such models. The inadequacies of spawner-recruit models were attributed variously to the effects of environmental uncertainty, to imperfect knowledge of population regulation, and to the lack of sufficient biological meaning in the models themselves. In general, impact assessment little resembles fishery regulation because the options and privileges commonly exercised by a fishery manager are closed to impact management. In either case, long-term forecasting remains unreliable due to the problem, as yet unsolved, of predicting reproduction and recruitment in natural populations. 21 refs., 1 fig

  10. Acute inhibition of estradiol synthesis impacts vestibulo-ocular reflex adaptation and cerebellar long-term potentiation in male rats.

    Science.gov (United States)

    Dieni, Cristina V; Ferraresi, Aldo; Sullivan, Jacqueline A; Grassi, Sivarosa; Pettorossi, Vito E; Panichi, Roberto

    2018-03-01

    The vestibulo-ocular reflex (VOR) adaptation is an ideal model for investigating how the neurosteroid 17 beta-estradiol (E2) contributes to the modification of behavior by regulating synaptic activities. We hypothesized that E2 impacts VOR adaptation by affecting cerebellar synaptic plasticity at the parallel fiber-Purkinje cell (PF) synapse. To verify this hypothesis, we investigated the acute effect of blocking E2 synthesis on gain increases and decreases in adaptation of the VOR in male rats using an oral dose (2.5 mg/kg) of the aromatase inhibitor letrozole. We also assessed the effect of letrozole on synaptic plasticity at the PF synapse in vitro, using cerebellar slices from male rats. We found that letrozole acutely impaired both gain increases and decreases adaptation of the VOR without altering basal ocular-motor performance. Moreover, letrozole prevented long-term potentiation at the PF synapse (PF-LTP) without affecting long-term depression (PF-LTD). Thus, in male rats neurosteroid E2 has a relevant impact on VOR adaptation and affects exclusively PF-LTP. These findings suggest that E2 might regulate changes in VOR adaptation by acting locally on cerebellar and extra-cerebellar synaptic plasticity sites.

  11. The Long-Term Impact of Foreign Multinational Enterprises in Spain: New Insights into an Old Topic

    Directory of Open Access Journals (Sweden)

    Núria Puig

    2016-07-01

    Full Text Available The role of foreign capital and technology in the economic and social progress of late-developing countries remains a controversial issue in both academic and policy circles. In this essay, we examine the case of Spain in the light of the academic literature from the 1960s to the present. First, we identify and contextualize the intellectual concerns and controversies of two important generations of economists and historians and their approaches to the specific issue of multinational enterprises (MNEs. We then discuss what we consider to be the seven major contributions of recent Spanish scholarship in terms of: 1/ new quantitative evidence on FDI inward flows and firm demography analyses of foreign MNEs; 2/ new approaches to the transfer of technology by MNEs; 3/ collective and individual case studies of foreign MNEs, with a focus on their impact on local capabilities; 4/ identification of patterns of investment by MNE home countries; 5/ identification and study of the local actors of inward FDI; 6/ new perspectives gained from the history of international relations; and 7 new evidence on processes leading from inward FDI to outward FDI. We argue that the time is ripe for comprehensive re-assessments of the long-term impact of foreign MNEs and the role of Spain in the global economy.

  12. Impact of human milk pasteurization on the kinetics of peptide release during in vitro dynamic term newborn digestion.

    Science.gov (United States)

    Deglaire, Amélie; De Oliveira, Samira C; Jardin, Julien; Briard-Bion, Valérie; Emily, Mathieu; Ménard, Olivia; Bourlieu, Claire; Dupont, Didier

    2016-07-01

    Holder pasteurization (62.5°C, 30 min) ensures sanitary quality of donor's human milk but also denatures beneficial proteins. Understanding whether this further impacts the kinetics of peptide release during gastrointestinal digestion of human milk was the aim of the present paper. Mature raw (RHM) or pasteurized (PHM) human milk were digested (RHM, n = 2; PHM, n = 3) by an in vitro dynamic system (term stage). Label-free quantitative peptidomics was performed on milk and digesta (ten time points). Ascending hierarchical clustering was conducted on "Pasteurization × Digestion time" interaction coefficients. Preproteolysis occurred in human milk (159 unique peptides; RHM: 91, PHM: 151), mostly on β-casein (88% of the endogenous peptides). The predicted cleavage number increased with pasteurization, potentially through plasmin activation (plasmin cleavages: RHM, 53; PHM, 76). During digestion, eight clusters resumed 1054 peptides from RHM and PHM, originating for 49% of them from β-casein. For seven clusters (57% of peptides), the kinetics of peptide release differed between RHM and PHM. The parent protein was significantly linked to the clustering (p-value = 1.4 E-09), with β-casein and lactoferrin associated to clusters in an opposite manner. Pasteurization impacted selectively gastric and intestinal kinetics of peptide release in term newborns, which may have further nutritional consequences. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. The Impact of Waiting List BMI Changes on the Short-term Outcomes of Lung Transplantation.

    Science.gov (United States)

    Jomphe, Valérie; Mailhot, Geneviève; Damphousse, Véronic; Tahir, Muhammad-Ramzan; Receveur, Olivier; Poirier, Charles; Ferraro, Pasquale

    2018-02-01

    Obesity and underweight are associated with a higher postlung transplantation (LTx) mortality. This study aims to assess the impact of the changes in body mass index (BMI) during the waiting period for LTx on early postoperative outcomes. Medical records of 502 consecutive cases of LTx performed at our institution between 1999 and 2015 were reviewed. Patients were stratified per change in BMI category between pre-LTx assessment (candidate BMI) and transplant BMI as follows: A-candidate BMI, less than 18.5 or 18.5 to 29.9 and transplant BMI, less than 18.5; B-candidate BMI, less than 18.5 and transplant BMI, 18.5 to 29.9; C-candidate BMI, 18.5 to 29.9 and transplant BMI, 18.5 to 29.9; D-candidate BMI, 30 or greater and transplant BMI, 18.5 to 29.9; and E-candidate BMI, 30 or greater or 18.5 to 29.9 and transplant BMI, 30 or greater. Our primary outcome was in-hospital mortality and secondary outcomes were length of mechanical ventilation, intensive care unit length of stay (LOS), hospital LOS and postoperative complications. BMI variation during the waiting time was common, as 1/3 of patients experienced a change in BMI category. Length of mechanical ventilation (21 days vs 9 days; P = 0.018), intensive care unit LOS (26 days vs 15 days; P = 0.035), and rates of surgical complications (76% vs 44%; P = 0.018) were significantly worse in patients of group E versus group D. Obese candidates who failed to decrease BMI less than 30 by transplant exhibited an increased risk of postoperative mortality (odds ratio, 2.62; 95% confidence interval, 1.01-6.48) compared with patients in group C. Pre-LTx BMI evolution had no impact on postoperative morbidity and mortality in underweight patients. Our results suggest that obese candidates with an unfavorable pretransplant BMI evolution are at greater risk of worse post-LTx outcomes.

  14. [A cohort study of longer-term impact of melamine contaminated formula on infant health].

    Science.gov (United States)

    Wang, Pei-xin; Li, Hong-tian; Wang, Lin-lin; Zhang, Long; Zhou, Yu-bo; Liu, Jian-meng

    2013-10-15

    in exposure group II were also higher than those in non-exposure group (P = 0.003 and 0.005). All affected infants have recovered from kidney abnormalities. Early infant exposure to melamine-contaminated milk formula appears to have no obvious impact on liver function and growth. But its potential impact on kidney function should be further assessed.

  15. Long-term Impacts of Hurricane Wilma on Land Surface-Atmosphere Exchanges

    Science.gov (United States)

    Fuentes, J. D.; Dowell, K. K.; Engel, V. C.; Smith, T. J.

    2008-05-01

    In October 2005, Hurricane Wilma made landfall along the mangrove forests of western Everglades National Park, Florida, USA. Damage from the storm varied with distance from landfall and included widespread mortality and extensive defoliation. Large sediment deposition events were recorded in the interior marshes, with erosion taking place along the coastal margins. Wilma made landfall near a 30 m flux tower where eddy-covariance measurements of ecosystem-level carbon and energy fluxes started in 2003. Repairs to the structure were completed in 2006, enabling comparisons of surface fluxes before and after the storm. One year after the hurricane, both the average and daily integrated CO2 fluxes are consistently lower than the pre-storm values. The storm's impact on standing live biomass and the slow recovery of leaf area appear to have resulted in decreased photosynthetic uptake capacity. Nighttime respiratory CO2 fluxes above the canopy are unchanged from pre-storm values. During some periods, daily integrated fluxes show the forest as a net source of CO2 to the atmosphere. Soil CO2 fluxes are not measured directly, but daytime soil temperatures and vertical heat fluxes have shown consistently higher values after the storm. Nighttime soil temperatures values have been slightly lower. These stronger diurnal soil temperature fluctuations indicate enhanced radiative fluxes at the soil surface, possibly as a result of the reduced leaf area. The increases in daytime soil temperatures are presumably leading to higher below-ground respiration rates and, along with the reduced photosynthetic capacity, contributing to the lower net CO2 assimilation rates. This hypothesis is supported by nearby measurements of declining surface elevations of the organic soils which have been correlated with mangrove mortality in impacted areas. Both sensible and latent heat fluxes above the canopy are found to be reduced following the hurricane, and soil heat storage is higher. Together

  16. Impact of Long-Term Treatment with Ivermectin on the Prevalence and Intensity of Soil-Transmitted Helminth Infections

    Science.gov (United States)

    Moncayo, Ana Lucia; Vaca, Maritza; Amorim, Leila; Rodriguez, Alejandro; Erazo, Silvia; Oviedo, Gisela; Quinzo, Isabel; Padilla, Margarita; Chico, Martha; Lovato, Raquel; Gomez, Eduardo; Barreto, Mauricio L.; Cooper, Philip J.

    2008-01-01

    Background Control of soil-transmitted helminth (STH) infections relies on the periodic and long-term administration of anthelmintic drugs to high-risk groups, particularly school-age children living in endemic areas. There is limited data on the effectiveness of long-term periodic anthelmintic treatment on the prevalence of STHs, particularly from operational programmes. The current study investigated the impact of 15 to 17 years of treatment with the broad-spectrum anthelmintic ivermectin, used for the control of onchocerciasis, on STH prevalence and intensity in school-age and pre-school children. Methods and Findings A cross-sectional study was conducted in communities that had received annual or twice-annual ivermectin treatments and geographically adjacent communities that had not received treatment in two districts of Esmeraldas Province in Ecuador. Stool samples were collected from school-age children and examined for STH infection using the Kato-Katz and formol-ether concentration methods. Samples were collected also from pre-school children and examined by the formol-ether concentration method. Data on risk factors for STH infection were collected by parental questionnaire. We sampled a total of 3,705 school-age children (6–16 years) from 31 treated and 27 non-treated communities, and 1,701 pre-school children aged 0–5 years from 18 treated and 18 non-treated communities. Among school-age children, ivermectin treatment had significant effects on the prevalence (adjusted OR =  0.06, 95% CI 0.03–0.14) and intensity of Trichuris trichiura infection (adjusted RR = 0.28, 95% CI 0.11–0.70), but appeared to have no impact on Ascaris lumbricoides or hookworm infection. Reduced prevalence and intensities of T. trichiura infection were observed among children not eligible to receive ivermectina, providing some evidence of reduced transmission of T. trichiura infection in communities receiving mass ivermectin treatments. Conclusion Annual and twice

  17. Long-term integrated river basin planning and management of water quantity and water quality in mining impacted catchments

    Science.gov (United States)

    Pohle, Ina; Zimmermann, Kai; Claus, Thomas; Koch, Hagen; Gädeke, Anne; Uhlmann, Wilfried; Kaltofen, Michael; Müller, Fabian; Redetzky, Michael; Schramm, Martina; Schoenheinz, Dagmar; Grünewald, Uwe

    2015-04-01

    During the last decades, socioeconomic change in the catchment of the Spree River, a tributary of the Elbe, has been to a large extent associated with lignite mining activities and the rapid decrease of these activities in the 1990s. There are multiple interconnections between lignite mining and water management both in terms of water quantity and quality. During the active mining period a large-scale groundwater depression cone has been formed while river discharges have been artificially increased. Now, the decommissioned opencast mines are being transformed into Europe's largest man-made lake district. However, acid mine drainage causes low pH in post mining lakes and high concentrations of iron and sulphate in post mining lakes and the river system. Next to potential changes in mining activities, also the potential impacts of climate change (increasing temperature and decreasing precipitation) on water resources of the region are of major interest. The fundamental question is to what extent problems in terms of water quantity and water quality are exacerbated and whether they can be mitigated by adaptation measures. In consequence, long term water resource planning in the region has to formulate adaptation measures to climate change and socioeconomic change in terms of mining activities which consider both, water quantity and water quality aspects. To assess potential impacts of climate and socioeconomic change on water quantity and water quality of the Spree River catchment up to the Spremberg reservoir in the scenario period up to 2052, we used a model chain which consists of (i) the regional climate model STAR (scenarios with a further increase in temperature of 0 and 2 K), (ii) mining scenarios (mining discharges, cooling water consumption of thermal power plants), (iii) the ecohydrological model SWIM (natural water balance), (iv) the long term water management model WBalMo (managed discharges, withdrawal of water users, reservoir operation) and (v) the

  18. Long-term impact of postoperative radiotherapy in carcinoma of the vulva FIGO I/II

    International Nuclear Information System (INIS)

    Busch, Martin; Wagener, Birgit; Schaffer, Moshe; Duehmke, Eckhart

    2000-01-01

    Purpose: Between 1953 and 1978, postoperative radiotherapy was used as an adjuvant therapy for carcinoma of the vulva that had not been treated with radical vulvectomy. We evaluated long-term results and possible prognostic factors. Methods and Materials: Ninety-two patients were treated. Surgical procedures were simple vulvectomy, electrocoagulation, or local excision. Radiotherapy doses to the vulva ranged from 0 to 90 Gy. All patients received radiotherapy to the inguinal lymph nodes, ranging from 30 to 60 Gy. Thirty-year retrospective follow-up was done evaluating the records and statistical survival rates. Results: Five-year actuarial survival rates in T1 patients were 71% (77% cause-specific survival rate), for T2 patients 43% (48% cause-specific survival rate). The difference between T1 and T2 patients was significant (p < 0.05). Patients with tumors of the labia minora had a significantly higher survival rate than those with different sites affected. Doses of 45 Gy or more to the vulva were sufficient to increase the 5-year cause-specific survival rate from 55% to 88%. The results in three subgroups were analyzed, group 1 having received electrocoagulation, but no radiotherapy of the vulva; group 2, local excision and doses of 40 Gy to the vulva; group 3, local excision and doses of 60 Gy to the vulva. There was a significant effect on 10-year cause-specific survival rates: 48% in group 1, 11% in group 2, and 88% in group 3. In multivariate analysis, the significant independent factors were T classification, tumor sites and--with only marginal significance--radiation doses to the vulva. Conclusions: The prognosis in early vulva carcinoma after nonradical surgery primarily depends on T classification and the site of the primary tumor. With univariate analyses, the dose has a significant effect on survival. In multivariate analyses the dose is a marginal independent factor in the whole group of patients. After nonradical surgery of early vulva carcinoma, the

  19. Long Term Development of Gut Microbiota Composition in Atopic Children: Impact of Probiotics

    Science.gov (United States)

    Rutten, N. B. M. M.; Gorissen, D. M. W.; Eck, A.; Niers, L. E. M.; Vlieger, A. M.; Besseling-van der Vaart, I.; Budding, A. E.; Savelkoul, P. H. M.; van der Ent, C. K.; Rijkers, G. T.

    2015-01-01

    Introduction Imbalance of the human gut microbiota in early childhood is suggested as a risk factor for immune-mediated disorders such as allergies. With the objective to modulate the intestinal microbiota, probiotic supplementation during infancy has been used for prevention of allergic diseases in infants, with variable success. However, not much is known about the long-term consequences of neonatal use of probiotics on the microbiota composition. The aim of this study was to assess the composition and microbial diversity in stool samples of infants at high-risk for atopic disease, from birth onwards to six years of age, who were treated with probiotics or placebo during the first year of life. Methods In a double-blind, randomized, placebo-controlled trial, a probiotic mixture consisting of B. bifidum W23, B. lactis W52 and Lc. Lactis W58 (Ecologic® Panda) was administered to pregnant women during the last 6 weeks of pregnancy and to their offspring during the first year of life. During follow-up, faecal samples were collected from 99 children over a 6-year period with the following time points: first week, second week, first month, three months, first year, eighteen months, two years and six years. Bacterial profiling was performed by IS-pro. Differences in bacterial abundance and diversity were assessed by conventional statistics. Results The presence of the supplemented probiotic strains in faecal samples was confirmed, and the probiotic strains had a higher abundance and prevalence in the probiotic group during supplementation. Only minor and short term differences in composition of microbiota were found between the probiotic and placebo group and between children with or without atopy. The diversity of Bacteroidetes was significantly higher after two weeks in the placebo group, and at the age of two years atopic children had a significantly higher Proteobacteria diversity (p < 0.05). Gut microbiota development continued between two and six years, whereby

  20. Litter quality impacts short- but not long-term soil carbon dynamics in soil aggregate fractions.

    Science.gov (United States)

    Gentile, Roberta; Vanlauwe, Bernard; Six, Johan

    2011-04-01

    Complex molecules are presumed to be preferentially stabilized as soil organic carbon (SOC) based on the generally accepted concept that the chemical composition of litter is a major factor in its rate of decomposition. Hence, a direct link between litter quality and SOC quantity has been assumed, accepted, and ultimately incorporated in SOC models. Here, however, we present data from an incubation and field experiment that refutes the influence of litter quality on the quantity of stabilized SOC. Three different qualities of litter (Tithonia diversifolia, Calliandra calothyrsus, and Zea mays stover; 4 Mg C x ha(-1) yr(-1)) with and without the addition of mineral N fertilizer (0 or 120 kg N x ha(-1)season(-1) were added to a red clay Humic Nitisol in a 3-yr field trial and a 1.5-yr incubation experiment. The litters differed in their concentrations of N, lignin, and polyphenols with the ratio of (lignin + polyphenols): N ranging from 3.5 to 9.8 for the field trial and from 2.3 to 4.0 for the incubation experiment in the order of T. diversifolia stabilized after three annual additions in the field trial. Even within the most sensitive soil aggregate fractions, SOC contents and C:N ratios did not differ with litter quality, indicating that litter quality did not influence the mechanisms by which SOC was stabilized. While increasing litter quality displayed faster decomposition and incorporation of C into soil aggregates after 0.25 yr in the incubation study, all litters resulted in equivalent amounts of C stabilized in the soil after 1.5 yr, further corroborating the results of the field trial. The addition of N fertilizer did not affect SOC stabilization in either the field or the incubation trial. Thus, we conclude that, while litter quality controls shorter-term dynamics of C decomposition and accumulation in the soil, longer-term SOC patterns cannot be predicted based on initial litter quality effects. Hence, the formation and stabilization of SOC is more