WorldWideScience

Sample records for imaging plasma diagnostics

  1. Recent Advancements in Microwave Imaging Plasma Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    H. Park; C.C. Chang; B.H. Deng; C.W. Domier; A.J.H. Donni; K. Kawahata; C. Liang; X.P. Liang; H.J. Lu; N.C. Luhmann, Jr.; A. Mase; H. Matsuura; E. Mazzucato; A. Miura; K. Mizuno; T. Munsat; K. and Y. Nagayama; M.J. van de Pol; J. Wang; Z.G. Xia; W-K. Zhang

    2002-03-26

    Significant advances in microwave and millimeter wave technology over the past decade have enabled the development of a new generation of imaging diagnostics for current and envisioned magnetic fusion devices. Prominent among these are revolutionary microwave electron cyclotron emission imaging (ECEI), microwave phase imaging interferometers, imaging microwave scattering and microwave imaging reflectometer (MIR) systems for imaging electron temperature and electron density fluctuations (both turbulent and coherent) and profiles (including transport barriers) on toroidal devices such as tokamaks, spherical tori, and stellarators. The diagnostic technology is reviewed, and typical diagnostic systems are analyzed. Representative experimental results obtained with these novel diagnostic systems are also presented.

  2. Statistical analysis of polarizing maps of blood plasma laser images for the diagnostics of malignant formations

    Science.gov (United States)

    Ungurian, V. P.; Ivashchuk, O. I.; Ushenko, V. O.

    2012-01-01

    This work is aimed at searching the interconnections between the statistic structure of blood plasma microscopic images and manifestations of optical anisotropy of liquid crystal protein network. The model of linear birefringence of albumin and globulin crystals underlies in the ground of this work. The results of investigating the interrelation between statistical moments of the 1st-4th order are presented that characterize the coordinate distributions of polarization ellipticity of laser images of blood plasma smears and pathological changes in human organism. The diagnostic criteria of breast cancer nascency and its severity degree differentiation are determined.

  3. Fast, Deep-Record-Length, Fiber-Coupled Photodiode Imaging Array for Plasma Diagnostics

    Science.gov (United States)

    Brockington, Samuel; Case, Andrew; Witherspoon, F. Douglas

    2015-11-01

    HyperV Technologies has been developing an imaging diagnostic comprised of an array of fast, low-cost, long-record-length, fiber-optically-coupled photodiode channels to investigate plasma dynamics and other fast, bright events. By coupling an imaging fiber bundle to a bank of amplified photodiode channels, imagers and streak imagers can be constructed. By interfacing analog photodiode systems directly to commercial analog-to-digital converters and modern memory chips, a scalable solution for 100 to 1000 pixel systems with 14 bit resolution and record-lengths of 128k frames has been developed. HyperV is applying these techniques to construct a prototype 1000 Pixel framing camera with up to 100 Msamples/sec rate and 10 to 14 bit depth. Preliminary experimental results as well as future plans will be discussed. Work supported by USDOE Phase 2 SBIR Grant DE-SC0009492.

  4. Synthetic aperture microwave imaging with active probing for fusion plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Shevchenko, Vladimir F.; Freethy, Simon J.; Huang, Billy K. [EURATOM/CCFE Fusion Association, Culham, Abingdon, Oxon, 0X14 3DB (United Kingdom); Vann, Roddy G. L. [York Plasma Institute, Dept. of Physics, University of York, York YO10 5DD (United Kingdom)

    2014-08-21

    A Synthetic Aperture Microwave Imaging (SAMI) system has been designed and built to obtain 2-D images at several frequencies from fusion plasmas. SAMI uses a phased array of linearly polarised antennas. The array configuration has been optimised to achieve maximum synthetic aperture beam efficiency. The signals received by antennas are down-converted to the intermediate frequency range and then recorded in a full vector form. Full vector signals allow beam focusing and image reconstruction in both real time and a post-processing mode. SAMI can scan over 16 pre-programmed frequencies in the range of 10-35GHz with a switching time of 300ns. The system operates in 2 different modes simultaneously: both a 'passive' imaging of plasma emission and also an 'active' imaging of the back-scattered signal of the radiation launched by one of the antennas from the same array. This second mode is similar to so-called Doppler backscattering (DBS) reflectometry with 2-D resolution of the propagation velocity of turbulent structures. Both modes of operation show good performance in fusion plasma experiments on Mega Amp Spherical Tokamak (MAST). We have obtained the first ever 2-D images of BXO mode conversion windows. With active probing, first ever turbulence velocity maps have been obtained. We present an overview of the diagnostic and discuss recent results. In contrast to quasi-optical microwave imaging systems SAMI requires neither big aperture viewing ports nor large 2-D detector arrays to achieve the desired imaging resolution. The number of effective 'pixels' of the synthesized image is proportional to the number of receiving antennas squared. Thus only a small number of optimised antennas is sufficient for the majority of applications. Possible implementation of SAMI on ITERand DEMO is discussed.

  5. Synthetic aperture microwave imaging with active probing for fusion plasma diagnostics

    Science.gov (United States)

    Shevchenko, Vladimir F.; Freethy, Simon J.; Huang, Billy K.; Vann, Roddy G. L.

    2014-08-01

    A Synthetic Aperture Microwave Imaging (SAMI) system has been designed and built to obtain 2-D images at several frequencies from fusion plasmas. SAMI uses a phased array of linearly polarised antennas. The array configuration has been optimised to achieve maximum synthetic aperture beam efficiency. The signals received by antennas are down-converted to the intermediate frequency range and then recorded in a full vector form. Full vector signals allow beam focusing and image reconstruction in both real time and a post-processing mode. SAMI can scan over 16 pre-programmed frequencies in the range of 10-35GHz with a switching time of 300ns. The system operates in 2 different modes simultaneously: both a 'passive' imaging of plasma emission and also an 'active' imaging of the back-scattered signal of the radiation launched by one of the antennas from the same array. This second mode is similar to so-called Doppler backscattering (DBS) reflectometry with 2-D resolution of the propagation velocity of turbulent structures. Both modes of operation show good performance in fusion plasma experiments on Mega Amp Spherical Tokamak (MAST). We have obtained the first ever 2-D images of BXO mode conversion windows. With active probing, first ever turbulence velocity maps have been obtained. We present an overview of the diagnostic and discuss recent results. In contrast to quasi-optical microwave imaging systems SAMI requires neither big aperture viewing ports nor large 2-D detector arrays to achieve the desired imaging resolution. The number of effective 'pixels' of the synthesized image is proportional to the number of receiving antennas squared. Thus only a small number of optimised antennas is sufficient for the majority of applications. Possible implementation of SAMI on ITERand DEMO is discussed.

  6. Diagnostics of Nanodusty Plasma

    Science.gov (United States)

    Greiner, Franko; Groth, Sebastian; Tadsen, Bejamin; Piel, Alexander

    2015-11-01

    The diagnostic of nanodusty plasmas, i.e. plasmas including nano-sized dust particles, is a challenging task. For both, the diagnostic of the nanodusty plasma itself, and the in-situ diagnostic of the nanoparticles, no standard diagnostic exist. Nanodust particle size and density can be estimated using light scattering techniques, namely kinetic Mie ellipsometry and extinction measurements. The charge of the nanoparticles can be estimated from the analysis of dust density waves (DDW). Parameters like the electron density, which give information about the plasma itself, may be deduced from the DDW analysis. We present detailed investigations on nanodust in a reactive Argon-Acetylene plasma created in an rf-driven parallel plate reactor at low pressure using the above mentioned portfolio of diagnostic. Funded by DFG under contract SFB TR-24/A2.

  7. Optical fiber imaging for high speed plasma motion diagnostics: applied to low voltage circuit breakers.

    Science.gov (United States)

    McBride, J W; Balestrero, A; Ghezzi, L; Tribulato, G; Cross, K J

    2010-05-01

    An integrated portable measurement system is described for the study of high speed and high temperature unsteady plasma flows such as those found in the vicinity of high current switching arcs. An array of optical fibers allows the formation of low spatial resolution images, with a maximum capture rate of 1 x 10(6) images per second (1 MHz), with 8 bit intensity resolution. Novel software techniques are reported to allow imaging of the arc; and to measure arc trajectories. Results are presented on high current (2 kA) discharge events in a model test fixture and on the application to a commercial low voltage circuit breaker.

  8. Imaging diagnostics of pulsed plasma discharges in saline generated with various sharp pin powered electrodes

    Science.gov (United States)

    Asimakoulas, L.; Karim, M. L.; Dostal, L.; Krcma, F.; Graham, W. G.; Field, T. A.

    2016-09-01

    Plasmas formed by 1 ms pulses of between 180 and 300 V applied to sharp pin-like electrodes immersed in saline solution have been imaged with a Photron SA-X2 fast framing camera and an Andor iStar 510 ICCD camera. Stainless steel, Tungsten and Gold electrodes were investigated with tip diameters of 30 μm, 1 μm and volume, which appears to move about, but remains close to the tip. In the case of Tungsten with higher voltages or longer pulses the tip of the needle can heat up to incandescent temperatures. At higher voltages shock wave fronts appear to be observed as the vapour layer collapses at the end of the voltage pulse. Backlighting and no lighting to observe bubble/vapour layer formation and emission due to plasma formation were employed. Sometimes at higher voltages a thicker vapour layer engulfs the tip and no plasma emission/current is observed.

  9. Synthetic aperture microwave imaging with active probing for fusion plasma diagnostics

    CERN Document Server

    Shevchenko, Vladimir F; Freethy, Simon J; Huang, Billy K

    2012-01-01

    A Synthetic Aperture Microwave Imaging (SAMI) system has been designed and built to obtain 2-D images at several frequencies from fusion plasmas. SAMI uses a phased array of linearly polarised antennas. The array configuration has been optimised to achieve maximum synthetic aperture beam efficiency. The signals received by antennas are down-converted to the intermediate frequency range and then recorded in a full vector form. Full vector signals allow beam focusing and image reconstruction in both real time and a post processing mode. SAMI can scan over 16 preprogrammed frequencies in the range of 10-35GHz with a switching time of 300ns. The system operates in 2 different modes simultaneously: both a passive imaging of plasma emission and also an active imaging of the back-scattered signal of the radiation launched by one of the antennas from the same array. This second mode is similar to so-called Doppler backscattering (DBS) reflectometry with 2-D resolution of the propagation velocity of turbulent structur...

  10. Diagnostics of hemangioma by the methods of correlation and fractal analysis of laser microscopic images of blood plasma

    Science.gov (United States)

    Boychuk, T. M.; Bodnar, B. M.; Vatamanesku, L. I.

    2012-01-01

    For the first time the complex correlation and fractal analysis was used for the investigation of microscopic images of both tissue images and hemangioma liquids. It was proposed a physical model of description of phase distributions formation of coherent radiation, which was transformed by optical anisotropic biological structures. The phase maps of laser radiation in the boundary diffraction zone were used as the main information parameter. The results of investigating the interrelation between the values of correlation (correlation area, asymmetry coefficient and autocorrelation function excess) and fractal (dispersion of logarithmic dependencies of power spectra) parameters are presented. They characterize the coordinate distributions of phase shifts in the points of laser images of histological sections of hemangioma, hemangioma blood smears and blood plasma with vascular system pathologies. The diagnostic criteria of hemangioma nascency are determined.

  11. Plasma diagnostics discharge parameters and chemistry

    CERN Document Server

    Auciello, Orlando

    1989-01-01

    Plasma Diagnostics, Volume 1: Discharge Parameters and Chemistry covers seven chapters on the important diagnostic techniques for plasmas and details their use in particular applications. The book discusses optical diagnostic techniques for low pressure plasmas and plasma processing; plasma diagnostics for electrical discharge light sources; as well as Langmuir probes. The text also describes the mass spectroscopy of plasmas, microwave diagnostics, paramagnetic resonance diagnostics, and diagnostics in thermal plasma processing. Electrical engineers, nuclear engineers, microwave engineers, che

  12. Imaging Techniques for Microwave Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Donne, T. [FOM-Institute for Plasma Physics Rijnhuizen, Trilateral Euregio Cluster, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Luhmann Jr, N.C. [University of California, Davis, CA 95616 (United States); Park, H.K. [POSTECH, Pohang, Gyeongbuk 790-784 (Korea, Republic of); Tobias, B.

    2011-07-01

    Advances in microwave technology have made it possible to develop a new generation of microwave imaging diagnostics for measuring the parameters of magnetic fusion devices. The most prominent of these diagnostics is electron cyclotron emission imaging (ECE-I). After the first generation of ECE-I diagnostics utilized at the TEXT-U, RTP and TEXTOR tokamaks and the LHD stellarator, new systems have recently come into operation on ASDEX-UG and DIII-D, soon to be followed by a system on KSTAR. The DIII-D and KSTAR systems feature dual imaging arrays that observe different parts of the plasma. The ECE-I diagnostic yields two-dimensional movies of the electron temperature in the plasma and has given already new insights into the physics of sawtooth oscillations, tearing modes and edge localized modes. Microwave Imaging Reflectometry (MIR) is used on LHD to measure electron density fluctuations. A pilot MIR system has been tested at TEXTOR and, based on the promising results, a new system is now under design for KSTAR. The system at TEXTOR was used to measure the plasma rotation velocity. The system at KSTAR and also the one on LHD will be/are used for measuring the profile of the electron density fluctuations in the plasma. Other microwave imaging diagnostics are phase imaging interferometry, and imaging microwave scattering. The emphasis in this paper will be largely focused on ECE-I. First an overview of the advances in microwave technology are discussed, followed by a description of a typical ECE-I system along with some typical experimental results. Also the utilization of imaging techniques in other types of microwave diagnostics will be briefly reviewed. This document is composed of the slides of the presentation. (authors)

  13. Synthetic diagnostics platform for fusion plasmas (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Shi, L., E-mail: lshi@pppl.gov; Valeo, E. J.; Tobias, B. J.; Kramer, G. J.; Hausammann, L.; Tang, W. M. [Princeton Plasma Physics Laboratory, Princeton, New Jersey 08540 (United States); Chen, M. [Department of Mechanical and Aerospace Engineering, University of California, Davis, California 95616 (United States)

    2016-11-15

    A Synthetic Diagnostics Platform (SDP) for fusion plasmas has been developed which provides state of the art synthetic reflectometry, beam emission spectroscopy, and Electron Cyclotron Emission (ECE) diagnostics. Interfaces to the plasma simulation codes GTC, XGC-1, GTS, and M3D-C{sup 1} are provided, enabling detailed validation of these codes. In this paper, we give an overview of SDP’s capabilities, and introduce the synthetic diagnostic modules. A recently developed synthetic ECE Imaging module which self-consistently includes refraction, diffraction, emission, and absorption effects is discussed in detail. Its capabilities are demonstrated on two model plasmas. The importance of synthetic diagnostics in validation is shown by applying the SDP to M3D-C{sup 1} output and comparing it with measurements from an edge harmonic oscillation mode on DIII-D.

  14. Microwave diagnostics of atmospheric plasmas

    Science.gov (United States)

    Scott, David

    Plasma treatment of biological tissues has tremendous potential due to the wide range of applications. Most plasmas have gas temperatures which greatly exceed room temperature. These are often utilized in electro-surgery for cutting and coagulating tissue. Another type of plasma, referred to as cold atmospheric plasma, or CAP, is characterized by heavy particle temperatures which are at or near room temperature. Due to this lack of thermal effect, CAP may provide less invasive medical procedures. Additionally, CAP have been demonstrated to be effective at targeting cancer cells while minimizing damage to the surrounding tissue. A recently fabricated Microwave Electron Density Device (MEDD) utilizes microwave scattering on small atmospheric plasmas to determine the electron plasma density. The MEDD can be utilized on plasmas which range from a fraction of a millimeter to several centimeters at atmospheric pressure when traditional methods cannot be applied. Microwave interferometry fails due to the small size of the plasma relative to the microwave wavelength which leads to diffraction and negligible phase change; electrostatic probes introduce very strong perturbation and are associated with difficulties of application in strongly-collisional atmospheric conditions; and laser Thomson scattering is not sensitive enough to measure plasma densities less than 1012 cm-3. The first part of this dissertation provides an overview of two types of small atmospheric plasma objects namely CAPs and plasmas utilized in the electro-surgery. It then goes on to describe the fabrication, testing and calibration of the MEDD facility. The second part of this dissertation is focused on the application of the MEDD and other diagnostic techniques to both plasma objects. A series of plasma images that illustrate the temporal evolution of a discharge created by an argon electrosurgical device operating in the coagulation mode and its behavior was analyzed. The discharge of the argon

  15. [Molecular diagnostics and imaging].

    Science.gov (United States)

    Fink, Christian; Fisseler-Eckhoff, Annette; Huss, Ralf; Nestle, Ursula

    2009-01-01

    Molecular diagnostic methods and biological imaging techniques can make a major contribution to tailoring patients' treatment needs with regard to medical, ethical and pharmaco-economic aspects. Modern diagnostic methods are already being used to help identify different sub-groups of patients with thoracic tumours who are most likely to benefit significantly from a particular type of treatment. This contribution looks at the most recent developments that have been made in the field of thoracic tumour diagnosis and analyses the pros and cons of new molecular and other imaging techniques in day-to-day clinical practice.

  16. Plasma diagnostics for tokamaks and stellarators

    Energy Technology Data Exchange (ETDEWEB)

    Stott, P. E.; Sanchez, J.

    1994-07-01

    A collection of papers on plasma diagnostics is presented. The papers show the state of the art developments in a series of techniques: Magnetic diagnostics, Edge diagnostics, Langmuir probes, Spectroscopy, Microwave and FIR diagnostics as well as Thomson Scattering. Special interest was focused on those diagnostics oriented to fluctuations measurements in the plasma. (Author) 451 refs.

  17. The cluster charge identification in the GEM detector for fusion plasma imaging by soft X-ray diagnostics

    Science.gov (United States)

    Czarski, T.; Chernyshova, M.; Malinowski, K.; Pozniak, K. T.; Kasprowicz, G.; Kolasinski, P.; Krawczyk, R.; Wojenski, A.; Zabolotny, W.

    2016-11-01

    The measurement system based on gas electron multiplier detector is developed for soft X-ray diagnostics of tokamak plasmas. The multi-channel setup is designed for estimation of the energy and the position distribution of an X-ray source. The focal measuring issue is the charge cluster identification by its value and position estimation. The fast and accurate mode of the serial data acquisition is applied for the dynamic plasma diagnostics. The charge clusters are counted in the space determined by 2D position, charge value, and time intervals. Radiation source characteristics are presented by histograms for a selected range of position, time intervals, and cluster charge values corresponding to the energy spectra.

  18. The cluster charge identification in the GEM detector for fusion plasma imaging by soft X-ray diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Czarski, T., E-mail: tomasz.czarski@ifpilm.pl; Chernyshova, M.; Malinowski, K. [Institute of Plasma Physics and Laser Microfusion, Hery 23, 01-497 Warsaw (Poland); Pozniak, K. T.; Kasprowicz, G.; Kolasinski, P.; Krawczyk, R.; Wojenski, A.; Zabolotny, W. [Warsaw University of Technology, Nowowiejska 15/19, 00-665 Warsaw (Poland)

    2016-11-15

    The measurement system based on gas electron multiplier detector is developed for soft X-ray diagnostics of tokamak plasmas. The multi-channel setup is designed for estimation of the energy and the position distribution of an X-ray source. The focal measuring issue is the charge cluster identification by its value and position estimation. The fast and accurate mode of the serial data acquisition is applied for the dynamic plasma diagnostics. The charge clusters are counted in the space determined by 2D position, charge value, and time intervals. Radiation source characteristics are presented by histograms for a selected range of position, time intervals, and cluster charge values corresponding to the energy spectra.

  19. Far infrared fusion plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Luhmann, N.C. Jr.; Peebles, W.A.

    1990-01-01

    Over the last several years, reflectometry has grown in importance as a diagnostic for both steady-state density Profiles as well as for the investigation of density fluctuations and turbulence. As a diagnostic for density profile measurement, it is generally believed to be well understood in the tokamak environment. However, its use as a fluctuation diagnostic is hampered by a lack of quantitative experimental understanding of its wavenumber sensitivity and spatial resolution. Several researchers, have theoretically investigated these questions. However, prior to the UCLA laboratory investigation, no group has experimentally investigated these questions. Because of the reflectometer's importance to the world effort in understanding plasma turbulence and transport, UCLA has, over the last year, made its primary Task IIIA effort the resolution of these questions. UCLA has taken the lead in a quantitative experimental understanding of reflectometer data as applied to the measurement of density fluctuations. In addition to this, work has proceeded on the design, construction, and installation of a reflectometer system on UCLA's CCT tokamak. This effort will allow a comparison between the improved confinement regimes (H-mode) observed on both the DIII-D and CCT machines with the goal of achieving a physics understanding of the phenomena. Preliminary investigation of a new diagnostic technique to measure density profiles as a function of time has been initiated at UCLA. The technique promises to be a valuable addition to the range of available plasma diagnostics. Work on advanced holographic reflectometry technique as applied to fluctuation diagnostics has awaited a better understanding of the reflectometer signal itself as discussed above. Efforts to ensure the transfer of the diagnostic developments have continued with particular attention devoted to the preliminary design of a multichannel FIR interferometer for MST.

  20. Advanced plasma diagnostics for plasma processing

    Science.gov (United States)

    Malyshev, Mikhail Victorovich

    1999-10-01

    A new, non-intrusive, non-perturbing diagnostic method was developed that can be broadly applied to low pressure, weakly ionized plasmas and glow discharges-trace rare gases optical emission spectroscopy (TRG-OES). The method is based on a comparison of intensities of atomic emission from trace amounts of inert gases (He, Ne, Ar, Kr, and Xe) that are added to the discharge to intensities calculated from the theoretical model. The model assumes a Maxwellian electron energy distribution function (EEDF), computes the population of emitting levels both from the ground state and the metastable states of rare gases, and from the best fit between theory and experiment determines electron temperature (Te). Subject to conditions, TRG-OES can also yield electron density or its upper or lower limit. From the comparison of the emission from levels excited predominantly by high energy electrons to that excited by low energy electrons, information about the EEDF can be obtained. The use of TRG-OES also allows a traditionally qualitative actinometry technique (determination of concentration of radical species in plasma through optical emission) to become a precise quantitative method by including Te and rare gases metastables effects. A combination of TRG-OES, advanced actinometry, and Langmuir probe measurements was applied to several different plasma reactors and regimes of operation. Te measurements and experiments to correct excitation cross section were conducted in a laboratory helical resonator. Two chamber configuration of a commercial (Lam Research) metal etcher were studied to determine the effects of plasma parameters on plasma-induced damage. Two different methods (RF inductive coupling and ultra-high frequency coupling) for generating a plasma in a prototype reactor were also studied. Pulsed plasmas, a potential candidate to eliminate the plasma-induced damage to microelectronics devices that occurs in manufacturing due to differential charging of the wafer, have

  1. A physical parameter method for the design of broad-band X-ray imaging systems to do coronal plasma diagnostics

    Science.gov (United States)

    Kahler, S.; Krieger, A. S.

    1978-01-01

    The technique commonly used for the analysis of data from broad-band X-ray imaging systems for plasma diagnostics is the filter ratio method. This requires the use of two or more broad-band filters to derive temperatures and line-of-sight emission integrals or emission measure distributions as a function of temperature. Here an alternative analytical approach is proposed in which the temperature response of the imaging system is matched to the physical parameter being investigated. The temperature response of a system designed to measure the total radiated power along the line of sight of any coronal structure is calculated. Other examples are discussed.

  2. Eight-channel Kirkpatrick-Baez microscope for multiframe x-ray imaging diagnostics in laser plasma experiments.

    Science.gov (United States)

    Yi, Shengzhen; Zhang, Zhe; Huang, Qiushi; Zhang, Zhong; Mu, Baozhong; Wang, Zhanshan; Fang, Zhiheng; Wang, Wei; Fu, Sizu

    2016-10-01

    Because grazing-incidence Kirkpatrick-Baez (KB) microscopes have better resolution and collection efficiency than pinhole cameras, they have been widely used for x-ray imaging diagnostics of laser inertial confinement fusion. The assembly and adjustment of a multichannel KB microscope must meet stringent requirements for image resolution and reproducible alignment. In the present study, an eight-channel KB microscope was developed for diagnostics by imaging self-emission x-rays with a framing camera at the Shenguang-II Update (SGII-Update) laser facility. A consistent object field of view is ensured in the eight channels using an assembly method based on conical reference cones, which also allow the intervals between the eight images to be tuned to couple with the microstrips of the x-ray framing camera. The eight-channel KB microscope was adjusted via real-time x-ray imaging experiments in the laboratory. This paper describes the details of the eight-channel KB microscope, its optical and multilayer design, the assembly and alignment methods, and results of imaging in the laboratory and at the SGII-Update.

  3. Eight-channel Kirkpatrick-Baez microscope for multiframe x-ray imaging diagnostics in laser plasma experiments

    Science.gov (United States)

    Yi, Shengzhen; Zhang, Zhe; Huang, Qiushi; Zhang, Zhong; Mu, Baozhong; Wang, Zhanshan; Fang, Zhiheng; Wang, Wei; Fu, Sizu

    2016-10-01

    Because grazing-incidence Kirkpatrick-Baez (KB) microscopes have better resolution and collection efficiency than pinhole cameras, they have been widely used for x-ray imaging diagnostics of laser inertial confinement fusion. The assembly and adjustment of a multichannel KB microscope must meet stringent requirements for image resolution and reproducible alignment. In the present study, an eight-channel KB microscope was developed for diagnostics by imaging self-emission x-rays with a framing camera at the Shenguang-II Update (SGII-Update) laser facility. A consistent object field of view is ensured in the eight channels using an assembly method based on conical reference cones, which also allow the intervals between the eight images to be tuned to couple with the microstrips of the x-ray framing camera. The eight-channel KB microscope was adjusted via real-time x-ray imaging experiments in the laboratory. This paper describes the details of the eight-channel KB microscope, its optical and multilayer design, the assembly and alignment methods, and results of imaging in the laboratory and at the SGII-Update.

  4. Complex polarization-phase and spatial-frequency selections of laser images of blood-plasma films in diagnostics of changes in their polycrystalline structure

    Science.gov (United States)

    Ushenko, Yu. A.; Angelskii, P. O.; Dubolazov, A. V.; Karachevtsev, A. O.; Sidor, M. I.; Mintser, O. P.; Oleinichenko, B. P.; Bizer, L. I.

    2013-10-01

    We present a theoretical formalism of correlation phase analysis of laser images of human blood plasma with spatial-frequency selection of manifestations of mechanisms of linear and circular birefringence of albumin and globulin polycrystalline networks. Comparative results of the measurement of coordinate distributions of the correlation parameter—the modulus of the degree of local correlation of amplitudes—of laser images of blood plasma taken from patients of three groups—healthy patients (donors), rheumatoid-arthritis patients, and breast-cancer patients—are presented. We investigate values and ranges of change of statistical (the first to fourth statistical moments), correlation (excess of autocorrelation functions), and fractal (slopes of approximating curves and dispersion of extrema of logarithmic dependences of power spectra) parameters of coordinate distributions of the degree of local correlation of amplitudes. Objective criteria for diagnostics of occurrence and differentiation of inflammatory and oncological states are determined.

  5. [Diagnostic imaging of lying].

    Science.gov (United States)

    Lass, Piotr; Sławek, Jarosław; Sitek, Emilia; Szurowska, Edyta; Zimmermann, Agnieszka

    2013-01-01

    Functional diagnostic imaging has been applied in neuropsychology for more than two decades. Nowadays, the functional magnetic resonance (fMRI) seems to be the most important technique. Brain imaging in lying has been performed and discussed since 2001. There are postulates to use fMRI for forensic purposes, as well as commercially, e.g. testing the loyalty of employees, especially because of the limitations of traditional polygraph in some cases. In USA fMRI is performed in truthfulness/lying assessment by at least two commercial companies. Those applications are a matter of heated debate of practitioners, lawyers and specialists of ethics. The opponents of fMRI use for forensic purposes indicate the lack of common agreement on it and the lack of wide recognition and insufficient standardisation. Therefore it cannot serve as a forensic proof, yet. However, considering the development of MRI and a high failure rate of traditional polygraphy, forensic applications of MRI seem to be highly probable in future.

  6. Diagnostic for the plasma liner experiment

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, M.; Merritt, E.; Lynn, A.G. [University of New Mexico, Albuquerque NM (United States); Bauer, B.S.; Fuelling, S.; Siemen, R.E. [University of Nevada, Reno NV (United States); Hsu, S.C. [Los Alamos National Laboratory, Los Alamos NM (United States); Witherspoon, F.D.; Brockington, S.; Case, A.; Messer, S.J. [HyperV Tecnologies Corp, Chantilly VA (United States); Cassibry, J.T. [University of Alabama, Huntsville AL (United States)

    2011-07-01

    Magneto-Inertial Fusion (MIF) includes a class of fusion energy concepts that seek to relax the required implosion times of inertial fusion to microseconds rather than nanoseconds by utilizing magnetized targets. The Plasma Liner Experiment (PLX) at Los Alamos National Laboratory will explore and demonstrate the feasibility of forming imploding spherical 'plasma liners' that can reach peak pressures {approx} 0.1 Mbar upon stagnation. The liners will be formed via merging of 30 - 60 dense, high Mach number plasma jets (M {approx} 10-35, v {approx} 50-70 km/s, jet radius {approx} 5 cm) in spherically convergent geometry. This is a staged, exploratory project where scientific issues will be studied first at modest stored energies ({approx} 300 kJ) before attempting to reach MIF-relevant pressures (requiring {approx} 1.5 MJ). Key physics issues include peak parameters (n, T, radius) at stagnation, dynamics of the merging jet liner formation (e.g. lateral shocks, instabilities), and spherical symmetry of the liner. Plasmas will be high-Z species (e.g. Ar, Xe), unmagnetized, and are expected to have densities {approx} 10{sup 22} m{sup -3} and low temperature, Te {approx} Ti {approx} a few eV, when initially exiting the plasma guns where the jets are formed. Density and temperature will first decrease slightly, then increase to n {approx} 10{sup 25} - 10{sup 26} m{sup -3} and Te {approx} Ti {approx} 100 eV as stagnation is approached over a 1 meter radial distance. The large range of densities (4-5 orders of magnitude), initially cold plasma, and short optical depth as the jets merge make diagnosing the plasma a particularly challenging problem. Initial diagnostics will include multi-chord visible interferometry and polarimetry, Schlieren imaging, visible and V-UV spectroscopy, fast 1-dimensional imaging diode arrays, fast visible cameras, bolometry, magnetic and electrostatic probes, and pressure sensitive 'witness plates' to measure pressure and jet

  7. The neutron imaging diagnostic at NIF (invited).

    Science.gov (United States)

    Merrill, F E; Bower, D; Buckles, R; Clark, D D; Danly, C R; Drury, O B; Dzenitis, J M; Fatherley, V E; Fittinghoff, D N; Gallegos, R; Grim, G P; Guler, N; Loomis, E N; Lutz, S; Malone, R M; Martinson, D D; Mares, D; Morley, D J; Morgan, G L; Oertel, J A; Tregillis, I L; Volegov, P L; Weiss, P B; Wilde, C H; Wilson, D C

    2012-10-01

    A neutron imaging diagnostic has recently been commissioned at the National Ignition Facility (NIF). This new system is an important diagnostic tool for inertial fusion studies at the NIF for measuring the size and shape of the burning DT plasma during the ignition stage of Inertial Confinement Fusion (ICF) implosions. The imaging technique utilizes a pinhole neutron aperture, placed between the neutron source and a neutron detector. The detection system measures the two dimensional distribution of neutrons passing through the pinhole. This diagnostic has been designed to collect two images at two times. The long flight path for this diagnostic, 28 m, results in a chromatic separation of the neutrons, allowing the independently timed images to measure the source distribution for two neutron energies. Typically the first image measures the distribution of the 14 MeV neutrons and the second image of the 6-12 MeV neutrons. The combination of these two images has provided data on the size and shape of the burning plasma within the compressed capsule, as well as a measure of the quantity and spatial distribution of the cold fuel surrounding this core.

  8. Optical diagnostics of femtosecond laser plasmas

    Institute of Scientific and Technical Information of China (English)

    李玉同; 张杰; 陈黎明; 夏江帆; 腾浩; 赵理曾; 林景全; 李英骏; 魏志义; 王龙; 江文勉

    2001-01-01

    Optical diagnostics of evolution of plasmas produced by ultrashort laser pulses is carried out using a femtosecond probing beam. The time sequence of plasma shadowgrams and interferograms are obtained. The filamentation instability in high_density region induces the local density modification. Large_scale toroidal magnetic fields confine plasma expansion in the transverse direction, resulting in the formation of a plasma jet. The plasma expansion along the target normal direction is found to scale as 1 2.

  9. Plasma diagnostics in plasma processing for nanotechnology and nanolevel chemistry

    Directory of Open Access Journals (Sweden)

    Hiroshi Akatsuka

    2004-01-01

    Full Text Available The author reviews the role of various plasma diagnostics in plasma processing for nanotechnology, and points out some essential methods of spectroscopic methods to diagnose plasmas for nanoprocessing. Two experimental examples are discussed between the characteristics of nanomaterials and plasma parameters. One is measurement of rotation temperature in processing of carbon nanotube. The other is that of vibrational temperature in surface nitriding of titanium by nitrogen plasma processing. We summarize what to measure and how to measure them from the technical viewpoint of plasma diagnostics.

  10. Imaging System and Plasma Imaging on HL-2A Tokamak

    Institute of Scientific and Technical Information of China (English)

    郑银甲; 冯震; 罗萃文; 刘莉; 李伟; 严龙文; 杨青巍; 刘永

    2004-01-01

    As a new diagnostic means, plasma-imaging system has been developed on the HL2A tokamak, with a basic understanding of plasma discharge scenario of the entire torus, checking the plasma position and the clearance between the plasma and the first wall during discharge. The plasma imaging system consists of (1) color video camera, (2) observation window and turn mirror,(3) viewing & collecting optics, (4) video cable, (5) Video capture card as well as PC. This paper mainly describes the experimental arrangement, plasma imaging system and detailed part in the system, along with the experimental results. Real-time monitoring of plasma discharge process,particularly distinguishing limitor and divertor configuration, the imaging system has become key diagnostic means and laid the foundation for further physical experiment on the HL-2A tokamak.

  11. Plasma diagnostics in two kinematic classes of CMEs observed by the Atmospheric Imaging Assembly onboard the Solar Dynamic Observatory

    Science.gov (United States)

    Chmielewska, E.; Tomczak, M.; Kołomański, S.; Mrozek, T.

    2016-11-01

    In order to study the dynamics and thermal properties of two kinematic classes of coronal mass ejections (CMEs) we analyzed two well-observed events in the early stage of their propagation, using multiwavelength observations from the Atmospheric Imaging Assembly (AIA) of the Solar Dynamic Observatory (SDO). For deriving differential emission measure (DEM) profiles and DEM maps of the basic structures of CMEs, we used two methods: the regularized inversion and the iterative forward-fitting approach. For the CME associated with a M2.0 class flare (CME-FL), we identified a hot, moving, blob-like feature which seems to be a candidate for a CME flux rope. Furthermore, an expanding system of loop and coronal dimming was clearly seen in AIA images. For the CME related to an eruptive prominence (CME-EP), we observed an eruptive plasmoid and a failed-eruption of cold plasma. However, we also recognized warm and hot moving signatures that revealed a multi-temperature nature of the eruptive prominence. Our main results are as follows: (a) An analysis of the examples of the two different kinematic classes of CMEs shows that despite the slight variations in the values of speeds and accelerations (CME-FL: v≈174 km s-1, a&ap350 m s-2; CME-EP: v≈135 km s-1, a≈160 m s-2) they present the same kinematic behavior; (b) in the field of view of the LASCO coronagraphs these two events have the similar, positive accelerations; (c) for both events we observed an impulsive acceleration phase (IAP); (d) the expanding structures seen in 171 Å, 193 Å, 211 Å in both events move faster than the hotter blobs; (e) the plasmoid core for the CME-FL is hot (8.0-15.8 MK); (f) the expanding blob and the hot structure in the prominence region for the CME-EP event have the similar temperature range (0.8-2.5 MK).

  12. ISTTOK plasma control with the tomography diagnostic

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, H.; Caralho, P.J.; Duarte, P.; Pereira, T.; Coelho, R.; Silva, C. [Association Euratom/IST, Institute of Plasmas and Nuclear Fusion, Technology Graduate Institute, P-1049-001 Lisbon (Portugal)

    2011-07-01

    A real-time plasma position control system is mandatory to achieve long duration (up to 250 ms), Alternating Current (AC) discharges on the ISTTOK tokamak. Such a system has been used for some time supported only on magnetic field diagnostic data. However, this system does not function accurately when the plasma current is low, rendering it inoperative during the plasma current reversal. A tomography diagnostic with 3 pinhole cameras and 8 silicone photodiode channels per camera was installed and customized to supply alternative plasma position to be used for plasma position control. As no filtering is applied, most of the radiation detected is in the visible/near-UV range. This system (i) executes a tomographic reconstruction, (ii) determines the average emissivity position from it, (iii) calculates the shift from the required position and (iv) supplies the vertical field power supply unit with the desired current value, all in less than 100 {mu}s. The horizontal magnetic field power supply unit is expected to be included in the system and will have no impact in the process time. This paper presents the tomography diagnostic architecture together with results of its scientific exploitation in ISTTOK AC discharges, where it has proven to be capable of supplying an accurate plasma position during the current reversal. The use of the tomography diagnostic for plasma position overcomes some limitations of the magnetic diagnostics, but poses challenges of its own such as blindness to plasma current direction. (authors)

  13. Some plasma aspects and plasma diagnostics of ion sources.

    Science.gov (United States)

    Wiesemann, Klaus

    2008-02-01

    We consider plasma properties in the most advanced type of plasma ion sources, electron cyclotron resonance ion sources for highly charged ions. Depending on the operation conditions the plasma in these sources may be highly ionized, which completely changes its transport properties. The most striking difference to weakly ionized plasma is that diffusion will become intrinsically ambipolar. We further discuss means of plasma diagnostics. As noninvasive diagnostic methods we will discuss analysis of the ion beam, optical spectroscopy, and measurement of the x-ray bremsstrahlung continuum. From beam analysis and optical spectroscopy one may deduce ion densities, and electron densities and distribution functions as a mean over the line of sight along the axis (optical spectroscopy) or at the plasma edge (ion beam). From x-ray spectra one obtains information about the population of highly energetic electrons and the energy transfer from the driving electromagnetic waves to the plasma -- basic data for plasma modeling.

  14. Diagnostics of laser ablated plasma plumes

    DEFF Research Database (Denmark)

    Amoruso, S.; Toftmann, B.; Schou, Jørgen;

    2004-01-01

    The effect of an ambient gas on the expansion dynamics of laser ablated plasmas has been studied for two systems by exploiting different diagnostic techniques. First, the dynamics of a MgB2 laser produced plasma plume in an Ar atmosphere has been investigated by space-and time-resolved optical...

  15. Plasma diagnostics surface analysis and interactions

    CERN Document Server

    Auciello, Orlando

    2013-01-01

    Plasmas and their interaction with materials have become subjects of major interest because of their importance in modern forefront technologies such as microelectronics, fusion energy, and space. Plasmas are used in microelectronics to process semiconductors (etching of patterns for microcircuits, plasma-induced deposition of thin films, etc.); plasmas produce deleterious erosion effects on surfaces of materials used for fusion devices and spaceships exposed to the low earth environment.Diagnostics of plasmas and materials exposed to them are fundamental to the understanding of the physical a

  16. Microwave Diagnostics of Ultracold Neutral Plasma

    CERN Document Server

    Guo, Ronghua Lu Li

    2010-01-01

    We suggest an approach for using microwave radiation in diagnostics of ultracold neutral plasma. Microwave scattering from ultracold neutral plasma is calculated . Simple formulations are get and indicate that the dipole radiation power of ultracold neutral plasma does not depend on density profile $n_e(r)$ and $\\omega$ when $\\omega\\gg\\omega_{pe0}$, but on the total electron number $N_e$. This method provides the information of $N_e$ and from which we can get the three body recombination rate of the plasma, which is extremely important in the researches of ultracold neutral plasma.

  17. The ear: Diagnostic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Vignaud, J.; Jardin, C.; Rosen, L.

    1986-01-01

    This is an English translation of volume 17-1 of Traite de radiodiagnostic and represents a reasonably complete documentation of the diseases of the temporal bone that have imaging manifestations. The book begins with chapters on embryology, anatomy and radiography anatomy; it continues with blood supply and an overview of temporal bone pathology. Subsequent chapters cover malformations, trauma, infections, tumors, postoperative changes, glomus tumors, vertebasilar insufficiency, and facial nerve canal lesions. A final chapter demonstrates and discusses magnetic resonance images of the ear and cerebellopontine angle.

  18. Diagnostic imaging in thyrotoxicosis.

    Science.gov (United States)

    Summaria, V; Salvatori, M; Rufini, V; Mirk, P; Garganese, M C; Romani, M

    1999-01-01

    In thyrotoxicosis, imaging mainly scintigraphy, color Doppler sonography and radioiodine uptake test are used in the differential diagnosis as well as in the morphofunctional evaluation of the thyroid before and after therapy (mainly pharmacological or with radioiodine). Radioiodine uptake test differentiates high uptake thyrotoxicosis (Graves'disease, toxic nodular goiter) and low uptake thyrotoxycosis (subacute or silent thyroiditis, ectopic thyrotoxicosis, iodine-induced hyperthyroidism). In Graves'disease scintigraphy shows thyroid enlargement with intense homogeneous tracer uptake; rarely nodules with no uptake are present. On color Doppler sonography, a part from enlargement, typical findings are: diffuse structural hypoechogenicity (at times with echoic nodules), parenchymal hypervascularization ("thyroid inferno"), high systolic velocities (PSV > 70-100 cm/sec) in inferior thyroid arteries. Scintigraphy is the only method able to evidence an autonomously functioning thyroid nodule and stage it (in association to clinical findings and TSH, FT3, FT4 determination) as: toxic, non toxic (or pretoxic) and compensated, depending on whether there is inhibition of extranodular tissue. A scintigraphically "hot" nodule appears hypervascularized on color Doppler sonography (especially in the toxic or pre-toxic phase) with high PSV (> 50-70 cm/sec) in the ipsilateral inferior thyroid artery. The most reliable parameters in the evaluation of the therapeutic efficacy are: decreases in thyroid (Graves'disease) or nodular (autonomously functioning nodule) volume; decreased radioiodine uptake (Graves'disease); functional recovery of suppressed parenchyma (autonomously functioning nodule); decreased PSV in the inferior thyroid arteries.

  19. Diagnostics of nonlocal plasmas: advanced techniques

    Science.gov (United States)

    Mustafaev, Alexander; Grabovskiy, Artiom; Strakhova, Anastasiya; Soukhomlinov, Vladimir

    2014-10-01

    This talk generalizes our recent results, obtained in different directions of plasma diagnostics. First-method of flat single-sided probe, based on expansion of the electron velocity distribution function (EVDF) in series of Legendre polynomials. It will be demonstrated, that flat probe, oriented under different angles with respect to the discharge axis, allow to determine full EVDF in nonlocal plasmas. It is also shown, that cylindrical probe is unable to determine full EVDF. We propose the solution of this problem by combined using the kinetic Boltzmann equation and experimental probe data. Second-magnetic diagnostics. This method is implemented in knudsen diode with surface ionization of atoms (KDSI) and based on measurements of the magnetic characteristics of the KDSI in presence of transverse magnetic field. Using magnetic diagnostics we can investigate the wide range of plasma processes: from scattering cross-sections of electrons to plasma-surface interactions. Third-noncontact diagnostics method for direct measurements of EVDF in remote plasma objects by combination of the flat single-sided probe technique and magnetic polarization Hanley method.

  20. Diagnostic imaging in bovine orthopedics.

    Science.gov (United States)

    Kofler, Johann; Geissbühler, Urs; Steiner, Adrian

    2014-03-01

    Although a radiographic unit is not standard equipment for bovine practitioners in hospital or field situations, ultrasound machines with 7.5-MHz linear transducers have been used in bovine reproduction for many years, and are eminently suitable for evaluation of orthopedic disorders. The goal of this article is to encourage veterinarians to use radiology and ultrasonography for the evaluation of bovine orthopedic disorders. These diagnostic imaging techniques improve the likelihood of a definitive diagnosis in every bovine patient but especially in highly valuable cattle, whose owners demand increasingly more diagnostic and surgical interventions that require high-level specialized techniques.

  1. THz time-domain spectroscopy for tokamak plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Causa, F.; Zerbini, M.; Buratti, P.; Gabellieri, L.; Pacella, D.; Romano, A.; Tuccillo, A. A.; Tudisco, O. [ASSOCIAZIONE EURATOM ENEA sulla Fusione, C. R. Frascati, via E. Fermi 45, 00044 Frascati (Roma) (Italy); Johnston, M. [Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU (United Kingdom); Doria, A.; Gallerano, G. P.; Giovenale, E. [ENEA C.R. Frascati UTAPRAD, via E. Fermi 45, 00044 Frascati (Roma) (Italy)

    2014-08-21

    The technology is now becoming mature for diagnostics using large portions of the electromagnetic spectrum simultaneously, in the form of THz pulses. THz radiation-based techniques have become feasible for a variety of applications, e.g., spectroscopy, imaging for security, medicine and pharmaceutical industry. In particular, time-domain spectroscopy (TDS) is now being used also for plasma diagnostics in various fields of application. This technique is promising also for plasmas for fusion applications, where plasma characteristics are non-uniform and/or evolve during the discharge This is because THz pulses produced with femtosecond mode-locked lasers conveniently span the spectrum above and below the plasma frequency and, thus, can be used as very sensitive and versatile probes of widely varying plasma parameters. The short pulse duration permits time resolving plasma characteristics while the large frequency span permits a large dynamic range. The focus of this work is to present preliminary experimental and simulation results demonstrating that THz TDS can be realistically adapted as a versatile tokamak plasma diagnostic technique.

  2. Online plasma diagnostics of a laser-produced plasma

    Science.gov (United States)

    Kai, Gao; Nasr, A. M. Hafz; Song, Li; Mohammad, Mirzaie; Guangyu, Li; Quratul, Ain

    2017-01-01

    In this study, we report a laser interferometry experiment for the online-diagnosing of a laser-produced plasma. The laser pulses generating the plasma are ultra-fast (30 femtoseconds), ultra-intense (tens of Terawatt) and are focused on a helium gas jet to generate relativistic electron beams via the laser wakefield acceleration (LWFA) mechanism. A probe laser beam (λ = 800 nm) which is split-off the main beam is used to cross the plasma at the time of arrival of the main pulse, allowing online plasma density diagnostics. The interferometer setup is based on the NoMarski method in which we used a Fresnel bi-prism where the probe beam interferes with itself after crossing the plasma medium. A high-dynamic range CCD camera is used to record the interference patterns. Based upon the Abel inversion technique, we obtained a 3D density distribution of the plasma density.

  3. Plasma Diagnostics by Antenna Impedance Measurements

    Science.gov (United States)

    Swenson, C. M.; Baker, K. D.; Pound, E.; Jensen, M. D.

    1993-01-01

    The impedance of an electrically short antenna immersed in a plasma provides an excellent in situ diagnostic tool for electron density and other plasma parameters. By electrically short we mean that the wavelength of the free-space electromagnetic wave that would be excited at the driving frequency is much longer than the physical size of the antenna. Probes using this impedance technique have had a long history with sounding rockets and satellites, stretching back to the early 1960s. This active technique could provide information on composition and temperature of plasmas for comet or planetary missions. Advantages of the impedance probe technique are discussed and two classes of instruments built and flown by SDL-USU for determining electron density (the capacitance and plasma frequency probes) are described.

  4. Diagnostics for the plasma liner experiment.

    Science.gov (United States)

    Lynn, A G; Merritt, E; Gilmore, M; Hsu, S C; Witherspoon, F D; Cassibry, J T

    2010-10-01

    The goal of the Plasma Liner Experiment (PLX) is to explore and demonstrate the feasibility of forming imploding spherical "plasma liners" via merging high Mach number plasma jets to reach peak liner pressures of ∼0.1 Mbar using ∼1.5 MJ of initial stored energy. Such a system would provide HED plasmas for a variety of fundamental HEDLP, laboratory astrophysics, and materials science studies, as well as a platform for experimental validation of rad-hydro and rad-MHD simulations. It could also prove attractive as a potential standoff driver for magnetoinertial fusion. Predicted parameters from jet formation to liner stagnation cover a large range of plasma density and temperature, varying from n(i)∼10(16) cm(-3), T(e)≈T(i)∼1 eV at the plasma gun mouth to n(i)>10(19) cm(-3), T(e)≈T(i)∼0.5 keV at stagnation. This presents a challenging problem for the plasma diagnostics suite which will be discussed.

  5. Plasma Diagnostics and Plasma-Surface Interactions in Inductively Coupled Plasmas

    OpenAIRE

    Titus, Monica Joy

    2010-01-01

    The semiconductor industry's continued trend of manufacturing device features on the nanometer scale requires increased plasma processing control and improved understanding of plasma characteristics and plasma-surface interactions. This dissertation presents a series of experimental results for focus studies conducted in an inductively coupled plasma (ICP) system. First novel "on-wafer" diagnostic tools are characterized and related to plasma characteristics. Second, plasma-polymer interactio...

  6. Canine Hip Dysplasia: Diagnostic Imaging.

    Science.gov (United States)

    Butler, J Ryan; Gambino, Jennifer

    2017-07-01

    Diagnostic imaging is the principal method used to screen for and diagnose hip dysplasia in the canine patient. Multiple techniques are available, each having advantages, disadvantages, and limitations. Hip-extended radiography is the most used method and is best used as a screening tool and for assessment for osteoarthritis. Distraction radiographic methods such as the PennHip method allow for improved detection of laxity and improved ability to predict future osteoarthritis development. More advanced techniques such as MRI, although expensive and not widely available, may improve patient screening and allow for improved assessment of cartilage health. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Infrared imaging diagnostics for INTF ion beam

    Science.gov (United States)

    Sudhir, D.; Bandyopadhyay, M.; Pandey, R.; Joshi, J.; Yadav, A.; Rotti, C.; Bhuyan, M.; Bansal, G.; Soni, J.; Tyagi, H.; Pandya, K.; Chakraborty, A.

    2015-04-01

    In India, testing facility named INTF [1] (Indian test facility) is being built in Institute for Plasma Research to characterize ITER-Diagnostic Neutral Beam (DNB). INTF is expected to deliver 60A negative hydrogen ion beam current of energy 100keV. The beam will be operated with 5Hz modulation having 3s ON/20s OFF duty cycle. To characterize the beam parameters several diagnostics are at different stages of design and development. One of them will be a beam dump, made of carbon fiber composite (CFC) plates placed perpendicular to the beam direction at a distance lm approximately. The beam dump needs to handle ˜ 6MW of beam power with peak power density ˜ 38.5MW/m2. The diagnostic is based on thermal (infra-red - IR) imaging of the footprint of the 1280 beamlets falling on the beam dump using four IR cameras from the rear side of the dump. The beam dump will be able to measure beam uniformity, beamlet divergence. It may give information on relative variation of negative ion stripping losses for different beam pulses. The design of this CFC based beam dump needs to address several physics and engineering issues, including some specific inputs from manufacturers. The manuscript will describe an overview of the diagnostic system and its design methodology highlighting those issues and the present status of its development.

  8. Optical diagnostics of dusty plasmas during nanoparticle growth

    Science.gov (United States)

    Mikikian, M.; Labidi, S.; von Wahl, E.; Lagrange, J. F.; Lecas, T.; Massereau-Guilbaud, V.; Géraud-Grenier, I.; Kovacevic, E.; Berndt, J.; Kersten, H.; Gibert, T.

    2017-01-01

    Carbon-based thin films deposited on surfaces exposed to a typical capacitively-coupled RF plasma are sources of molecular precursors at the origin of nanoparticle growth. This growth leads to drastic changes of the plasma characteristics. Thus, a precise understanding of the dusty plasma structure and dynamics is required to control the plasma evolution and the nanoparticle growth. Optical diagnostics can reveal some particular features occurring in these kinds of plasmas. High-speed imaging of the plasma glow shows that instabilities induced by nanoparticle growth can be constituted of small brighter plasma regions (plasmoids) that rotate around the electrodes. A single bigger region of enhanced emission is also of particular interest: the void, a main central dust-free region, has very distinct plasma properties than the surrounding dusty region. This particularity is emphasized using optical emission spectroscopy with spatiotemporal resolution. Emission profiles are obtained for the buffer gas and the carbonaceous molecules giving insights on the changes of the electron energy distribution function during dust particle growth. Dense clouds of nanoparticles are shown to be easily formed from two different thin films, one constituted of polymer and the other one created by the plasma decomposition of ethanol.

  9. Adaptive Embedded Digital System for Plasma Diagnostics

    Science.gov (United States)

    González, Angel; Rodríguez, Othoniel; Mangual, Osvaldo; Ponce, Eduardo; Vélez, Xavier

    2014-05-01

    An Adaptive Embedded Digital System to perform plasma diagnostics using electrostatic probes was developed at the Plasma Engineering Laboratory at Polytechnic University of Puerto Rico. The system will replace the existing instrumentation at the Laboratory, using reconfigurable hardware to minimize the equipment and software needed to perform diagnostics. The adaptability of the design resides on the possibility of replacing the computational algorithm on the fly, allowing to use the same hardware for different probes. The system was prototyped using Very High Speed Integrated Circuits Hardware Description Language (VHDL) into an Field Programmable Gate Array (FPGA) board. The design of the Embedded Digital System includes a Zero Phase Digital Filter, a Derivative Unit, and a Computational Unit designed using the VHDL-2008 Support Library. The prototype is able to compute the Plasma Electron Temperature and Density from a Single Langmuir probe. The system was tested using real data previously acquired from a single Langmuir probe. The plasma parameters obtained from the embedded system were compared with results computed using matlab yielding excellent matching. The new embedded system operates on 4096 samples versus 500 on the previous system, and completes its computations in 26 milliseconds compared with about 15 seconds on the previous system.

  10. Synchronous imaging of coherent plasma fluctuations

    Science.gov (United States)

    Haskey, S. R.; Thapar, N.; Blackwell, B. D.; Howard, J.

    2014-03-01

    A new method for imaging high frequency plasma fluctuations is described. A phase locked loop and field programmable gate array are used to generate gating triggers for an intensified CCD camera. A reference signal from another diagnostic such as a magnetic probe ensures that the triggers are synchronous with the fluctuation being imaged. The synchronous imaging technique allows effective frame rates exceeding millions per second, good signal to noise through the accumulation of multiple exposures per frame, and produces high resolution images without generating excessive quantities of data. The technique can be used to image modes in the MHz range opening up the possibility of spectrally filtered high resolution imaging of MHD instabilities that produce sufficient light fluctuations. Some examples of projection images of plasma fluctuations on the H-1NF heliac obtained using this approach are presented here.

  11. Streak Tubes for Diagnostics of Lasers and Plasmas

    Science.gov (United States)

    Sokolov, A. Yu; Konovalov, P. I.; Nurtdinov, R. I.; Vikulin, M. P.; Pryanishnikov, I. G.; Dolotov, A. S.; Krapiva, P. S.

    2016-09-01

    Designing a facility for laser fusion research requires sufficient advancement in diagnostics techniques for lasers and plasmas, including those involving streak camera imaging. Maximum specifications of streak cameras depend on the parameters of streak tubes. The paper illustrates how these devices function, and which of their parameters are limiting. The paper presents a novel technological platform designed at VNIIA, which was used to develop a new generation of streak tubes. Using these streak tubes in streak cameras, the efficiency of streak camera imaging techniques can be improved by several orders of magnitude, and new techniques can be designed.

  12. Comparative analyses of plasma probe diagnostics techniques

    Energy Technology Data Exchange (ETDEWEB)

    Godyak, V. A. [Electrical Engineering and Computer Science Department, University of Michigan, Ann Arbor, Michigan 48109, USA and RF Plasma Consulting, Brookline, Massachusetts 02446 (United States); Alexandrovich, B. M. [Plasma Sensors, Brookline, Massachusetts 02446 (United States)

    2015-12-21

    The subject of this paper is a comparative analysis of the plasma parameters inferred from the classical Langmuir probe procedure, from different theories of the ion current to the probe, and from measured electron energy distribution function (EEDF) obtained by double differentiation of the probe characteristic. We concluded that the plasma parameters inferred from the classical Langmuir procedure can be subjected to significant inaccuracy due to the non-Maxwellian EEDF, uncertainty of locating the plasma potential, and the arbitrariness of the ion current approximation. The plasma densities derived from the ion part of the probe characteristics diverge by as much as an order of magnitude from the density calculated according to Langmuir procedure or calculated as corresponding integral of the measured EEDF. The electron temperature extracted from the ion part is always subjected to uncertainty. Such inaccuracy is attributed to modification of the EEDF for fast electrons due to inelastic electron collisions, and to deficiencies in the existing ion current theories; i.e., unrealistic assumptions about Maxwellian EEDFs, underestimation of the ion collisions and the ion ambipolar drift, and discounting deformation of the one-dimensional structure of the region perturbed by the probe. We concluded that EEDF measurement is the single reliable probe diagnostics for the basic research and industrial applications of highly non-equilibrium gas discharge plasmas. Examples of EEDF measurements point up importance of examining the probe current derivatives in real time and reiterate significance of the equipment technical characteristics, such as high energy resolution and wide dynamic range.

  13. Charge Diagnostics for Laser Plasma Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, K.; Gonsalves, A. J.; Lin, C.; Sokollik, T.; Smith, A.; Rodgers, D.; Donahue, R.; Bryne, W.; Leemans, W. P.

    2010-06-01

    The electron energy dependence of a scintillating screen (Lanex Fast) was studied with sub-nanosecond electron beams ranging from 106 MeV to 1522 MeV at the Lawrence Berkeley National Laboratory Advanced Light Source (ALS) synchrotron booster accelerator. The sensitivity of the Lanex Fast decreased by 1percent per 100 MeV increase of the energy. The linear response of the screen against the charge was verified with charge density and intensity up to 160 pC/mm2 and 0.4 pC/ps/mm2, respectively. For electron beams from the laser plasma accelerator, a comprehensive study of charge diagnostics has been performed using a Lanex screen, an integrating current transformer, and an activation based measurement. The charge measured by each diagnostic was found to be within +/-10 percent.

  14. Filterscope edge plasma diagnostic for the W7-X stellarator

    Science.gov (United States)

    Harris, Jeffrey; Unterberg, Ezekial; Lore, Jeremy; Stephey, Laurie; Schmitz, Oliver; Wurden, Glen; Biedermann, Christoph; Krychowiak, Maciej; Koenig, Ralf

    2015-11-01

    W7-X is a large (R = 5.5m, a = 0.5m, B 10 MW) superconducting stellarator at the Max-Planck Institut für Plasmaphysik in Greifswald, Germany, which will begin plasma operations in the last quarter of 2015. We describe here the first measurements with a 24-channel filterscope diagnostic [E. A. Unterberg et al., Rev. Sci. Instrum. 83, 10D722, (2012)] of edge plasma characteristics and spectral emission from impurities near the test limiters installed for initial plasma experiments. These measurements, together with high resolution IR thermography imaging of the limiter, will be used as inputs for edge transport modeling using the EMC3 code [J. D. Lore et al., Nucl. Fusion 52, 0540 (2012)]. This work is sponsored by DOE Contract No. DE-AC05- 00OR22725 with UT-Battelle.

  15. CO{sub 2} laser diagnostics for measurements of the plasma density profile and plasma density fluctuations on LHD

    Energy Technology Data Exchange (ETDEWEB)

    Vyacheslavov, L.N. [Budker Institute of Nuclear Physics, Novosibirsk (Russian Federation); Tanaka, K.; Kawahata, K. [National Inst. for Fusion Science, Toki, Gifu (Japan)

    2001-04-01

    A CO{sub 2} laser based diagnostics complimentary to the existing FIR interferometer is proposed. It combines interferometry for plasma density profile measurement under conditions of large density gradients, and both imaging and scattering techniques for observation of plasma fluctuations. Two-colour interferometer with a slablike probe beam and a single multichannel linear detector array provide observation of plasma density profile and density fluctuations at two locations along the probe beam. Basic characteristics of the diagnostics are considered as well as some effects that include dispersion and are critical for two colour imaging technique. The results of the bench-top experiments with the prototype of the interferometer are presented. (author)

  16. Compact collimated fiber optic array diagnostic for railgun plasma experiments

    Energy Technology Data Exchange (ETDEWEB)

    Tang, V; Solberg, J; Ferriera, T; Tully, L; Stephan, P

    2008-10-02

    We have developed and tested a compact collimated sixteen channel fiber optic array diagnostic for studying the light emission of railgun armature plasmas with {approx}mm spatial and sub-{micro}s temporal resolution. The design and operational details of the diagnostic are described. Plasma velocities, oscillation, and dimension data from the diagnostic for the Livermore Fixed Hybrid Armature experiment are presented and compared with 1-D simulations. The techniques and principles discussed allow the extension of the diagnostic to other railgun and related dense plasma experiments.

  17. Compact collimated fiber optic array diagnostic for railgun plasmas.

    Science.gov (United States)

    Tang, V; Solberg, J M; Ferriera, T J; Tully, L K; Stephan, P L

    2009-01-01

    We developed and tested a compact collimated 16 channel fiber optic array diagnostic for studying the light emission of railgun armature plasmas with approximately millimeter spatial and submicrosecond temporal resolution. The design and operational details of the diagnostic are described. Plasma velocities, oscillation, and dimension data from the diagnostic for the Livermore fixed hybrid armature experiment are presented and compared with one-dimensional simulations. The techniques and principles discussed allow the extension of the diagnostic to other railgun and related dense plasma experiments.

  18. Radiogenomic imaging-linking diagnostic imaging and molecular diagnostics

    Institute of Scientific and Technical Information of China (English)

    Mathias; Goyen

    2014-01-01

    Radiogenomic imaging refers to the correlation between cancer imaging features and gene expression and is one of the most promising areas within science and medicine. High-throughput biological techniques have reshaped the perspective of biomedical research allowing for fast and efficient assessment of the entire molecular topography of a cell’s physiology providing new insights into human cancers. The use of non-invasive imaging tools for gene expression profiling of solid tumors could serve as a means for linking specific imaging features with specific gene expression patterns thereby allowing for more accurate diagnosis and prognosis and obviating the need for high-risk invasive biopsy procedures. This review focuses on the medical imaging part as one of the main drivers for the development of radiogenomic imaging.

  19. Passive Spectroscopic Diagnostics for Magnetically-confined Fusion Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Stratton, B. C.; Biter, M.; Hill, K. W.; Hillis, D. L.; Hogan, J. T.

    2007-07-18

    Spectroscopy of radiation emitted by impurities and hydrogen isotopes plays an important role in the study of magnetically-confined fusion plasmas, both in determining the effects of impurities on plasma behavior and in measurements of plasma parameters such as electron and ion temperatures and densities, particle transport, and particle influx rates. This paper reviews spectroscopic diagnostics of plasma radiation that are excited by collisional processes in the plasma, which are termed 'passive' spectroscopic diagnostics to distinguish them from 'active' spectroscopic diagnostics involving injected particle and laser beams. A brief overview of the ionization balance in hot plasmas and the relevant line and continuum radiation excitation mechanisms is given. Instrumentation in the soft X-ray, vacuum ultraviolet, ultraviolet, visible, and near-infrared regions of the spectrum is described and examples of measurements are given. Paths for further development of these measurements and issues for their implementation in a burning plasma environment are discussed.

  20. Diagnostic techniques for measuring suprathermal electron dynamics in plasmas (invited).

    Science.gov (United States)

    Coda, S

    2008-10-01

    Plasmas, both in the laboratory and in space, are often not in thermodynamic equilibrium, and the plasma electron distribution function is accordingly non-Maxwellian. Suprathermal electron tails can be generated by external drives, such as rf waves and electric fields, or internal ones, such as instabilities and magnetic reconnection. The variety and importance of the phenomena in which suprathermal electrons play a significant role explains an enduring interest in diagnostic techniques to investigate their properties and dynamics. X-ray bremsstrahlung emission has been studied in hot magnetized plasmas for well over two decades, flanked progressively by electron-cyclotron emission in geometries favoring the high-energy end of the distribution function (high-field-side, vertical, oblique emission), by electron-cyclotron absorption, by spectroscopic techniques, and at lower temperatures, by Langmuir probes and electrostatic analyzers. Continuous progress in detector technology and in measurement and analysis techniques, increasingly sophisticated layouts (multichannel and tomographic systems, imaging geometries), and highly controlled suprathermal generation methods (e.g., perturbative rf modulation) have all been brought to bear in recent years on an increasingly detailed, although far from complete, understanding of suprathermal electron dynamics.

  1. Clinics in diagnostic imaging (175)

    Science.gov (United States)

    Krishnan, Vijay; Lim, Tze Chwan; Ho, Francis Cho Hao; Peh, Wilfred CG

    2017-01-01

    A 54-year-old man presented with change in behaviour, nocturnal enuresis, abnormal limb movement and headache of one week’s duration. The diagnosis of butterfly glioma (glioblastoma multiforme) was made based on imaging characteristics and was further confirmed by biopsy findings. As the corpus callosum is usually resistant to infiltration by tumours, a mass that involves and crosses the corpus callosum is suggestive of an aggressive neoplasm. Other neoplastic and non-neoplastic conditions that may involve the corpus callosum and mimic a butterfly glioma, as well as associated imaging features, are discussed. PMID:28361164

  2. Second topical conference on high-temperature plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Jahoda, F.C.; Freese, K.B. (comps.)

    1978-02-01

    This report contains the program and abstracts of papers presented at the Second American Physical Society Topical Conference on High Temperature Plasma Diagnostics, March 1-3, 1978, Santa Fe, New Mexico.

  3. Advancements of microwave diagnostics in magnetically confined plasmas

    NARCIS (Netherlands)

    Mase, A.; Kogi, Y.; Ito, N.; Yokota, Y.; Akaki, K.; Kawahata, K.; Nagayama, Y.; Tokuzawa, T.; Yamaguchi, S.; Hojo, H.; Oyama, N.; N C Luhmann Jr.,; Park, H. K.; Donne, A. J. H.

    2009-01-01

    Microwave to millimeter-wave diagnostic techniques such as interferometry, reflectometry, scattering and radiometry have been powerful tools for diagnosing magnetically confined plasmas. Recent advances in electronic devices and components together with computer technology have enabled the developme

  4. Advanced Laser and RF Plasma Sources and Diagnostics

    Science.gov (United States)

    2007-06-13

    jacks, fibers, collimators, and breadboards $19,832.71 Interferometry Gunn diode and I-Q mixer $6,775.00 RF Components and Automation High...temperature diagnostics for both our laser window and radiofrequency air plasmas. We have also acquired a tunable 668 nm diode laser, optical filters...diagnostics for both our laser window and radiofrequency air plasmas. We have also acquired a tunable 668 nm diode laser, optical filters, splitters

  5. Plasma diagnostics and plasma-surface interactions in inductively coupled plasmas

    Science.gov (United States)

    Titus, Monica Joy

    The semiconductor industry's continued trend of manufacturing device features on the nanometer scale requires increased plasma processing control and improved understanding of plasma characteristics and plasma-surface interactions. This dissertation presents a series of experimental results for focus studies conducted in an inductively coupled plasma (ICP) system. First novel "on-wafer" diagnostic tools are characterized and related to plasma characteristics. Second, plasma-polymer interactions are characterized as a function of plasma species and processing parameters. Complementary simulations accompany each focus study to supplement experimental findings. Wafer heating mechanisms in inductively coupled molecular gas plasmas are explored with PlasmaTemp(TM), a novel "on-wafer" diagnostic tool. Experimental wafer measurements are obtained with the PlasmaTemp(TM) wafer processed in argon (Ar) and argon-oxygen (Ar/O2) mixed plasmas. Wafer heating mechanisms were determined by combining the experimental measurements with a 3-dimensional heat transfer model of the wafer. Comparisons between pure Ar and Ar/O2 plasmas demonstrate that two additional wafer heating mechanisms can be important in molecular gas plasmas compared to atomic gas discharges. Thermal heat conduction from the neutral gas and O-atom recombination on wafer surface can contribute as much as 60% to wafer heating under conditions of low-energy ion bombardment in molecular plasmas. Measurements of a second novel "on-wafer" diagnostic sensor, the PlasmaVolt(TM), were tested and validated in the ICP system for Ar plasmas varying in power and pressure. Sensor measurements were interpreted with a numerical sheath simulation and comparison to scaling laws derived from the inhomogeneous sheath model. The study demonstrates sensor measurements are proportional to the RF-current through the sheath and the scaling is a function of sheath impedance. PlasmaVolt(TM) sensor measurements are proportional to the

  6. Clinics in diagnostic imaging (171)

    Science.gov (United States)

    Ooi, Su Kai Gideon; Tan, Tien Jin; Ngu, James Chi Yong

    2016-01-01

    A 46-year-old Chinese woman with a history of cholecystectomy and appendicectomy presented to the emergency department with symptoms of intestinal obstruction. Physical examination revealed central abdominal tenderness but no clinical features of peritonism. Plain radiography of the abdomen revealed a grossly distended large bowel loop with the long axis extending from the right lower abdomen toward the epigastrium, and an intraluminal air-fluid level. These findings were suspicious for an acute caecal volvulus, which was confirmed on subsequent contrast-enhanced computed tomography (CT) of the abdomen and pelvis. CT demonstrated an abnormal positional relationship between the superior mesenteric vein and artery, indicative of an underlying intestinal malrotation. This case highlights the utility of preoperative imaging in establishing the diagnosis of an uncommon cause of bowel obstruction. It also shows the importance of recognising the characteristic imaging features early, so as to ensure appropriate and expedient management, thus reducing patient morbidity arising from complications. PMID:27872936

  7. Diagnostic imaging of lipoma arborescens

    Energy Technology Data Exchange (ETDEWEB)

    Martin, S.; Hernandez, L.; Romero, J.; Lafuente, J.; Poza, A.I.; Ruiz, P. [Servicio de Radiodiagnostico, Hospital General Universitario Gregorio Maranon, c/Dr. Esquerdo, 46, E-28007 Madrid (Spain); Jimeno, M. [Servicio de Anatomia Patologica, Hospital General Universitario Gregorio Maranon, c/Dr. Esquerdo, 46, E-28007 Madrid (Spain)

    1998-06-01

    Objective. The imaging characteristics of lipoma arborescens using plain radiographs, computed tomography (CT), and magnetic resonance imaging (MRI) are described. Design and patients. Five patients with a diagnosis of lipoma arborescens are presented. Three had monoarticular involvement of the knee joint. In the remaining two patients both knees and both hips, respectively, were affected. All patients were examined using plain radiographs and MRI. CT was employed in two cases. Results and conclusions. A conclusive diagnosis with exclusion of other synovial pathologies having similar clinical and radiological behaviour can be achieved on the basis of the MRI characteristics of lipoma arborescens. The aetiology of lipoma arborescens remains unknown, but its association with previous pathology of the affected joints in all our patients supports the theory of a non-neoplastic reactive process involving the synovial membrane. (orig.) With 5 figs., 18 refs.

  8. Atmospheric Pressure Plasma Based Flame Control and Diagnostics

    Science.gov (United States)

    2015-01-01

    TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Atmospheric Pressure Plasma Based Flame Control and Diagnostics 5a...to 10%)  Flame speed enhancement (>20%)  Extension of lean limit (factor of two)  Distributed ignition  Development of new diagnostics

  9. Plasma diagnostics in a pulsed accelerator used for material processing

    Energy Technology Data Exchange (ETDEWEB)

    Zhukeshov, A [Science Research Institute of Experimental and Theoretical Physics, al-Farabi Kazakh National University, 96a Tole bi str., 050012 Almaty (Kazakhstan)

    2007-04-15

    Results of research work of a pulsed plasma accelerator, designed as diagnostic and material science stands in SRIETP are presented. We present results on the development of electric and magnetic probes used for measurement of plasma parameters. The physical properties and changes in structure of vanadium alloy, common quality carbon and stainless steels have been investigated as well.

  10. Application of particle image velocimetry to dusty plasma systems

    Science.gov (United States)

    Williams, Jeremiah D.

    2016-06-01

    > Particle image velocimetry is a fluid measurement technique that has been used for more than 20 years to characterize the particle transport and thermal state of dusty plasma systems. This manuscript provides an overview of this diagnostic technique, highlighting the strengths and limitations that are associated with its use. Additionally, the variations of this technique that have been applied in the study of dusty plasma systems will be discussed, along with a small selection of measurements that can be made with the technique. Potential future directions for this diagnostic tool within the dusty plasma community will also be discussed.

  11. Development of innovative thermal plasma and particle diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, Benjamin-Leon

    2013-09-24

    Three original plasma diagnostic systems have been developed to investigate transient three-dimensional plasma processes with high spatial and temporal resolution. The developed diagnostics have been analyzed and tested by increasing the complexity from a stationary free burning Argon arc to a dc pulsed process and finally to a transient gas metal arc including droplet transfer through the plasma. The transient plasma parameters that have been determined include three-dimensional axially symmetric plasma densities (n{sub e}, n{sub A}, n{sub A+}, n{sub A++}), electron temperatures (T{sub e}), electrical conductivities (σ{sub el}), magnetic flux densities (B) and current densities (j{sub el}). In the case of a droplet transfer through an arc consisting of an Iron/Argon plasma, the droplet density, surface tension, viscosity, and temperature have been determined.

  12. Status and challenges in electrical diagnostics of processing plasmas

    DEFF Research Database (Denmark)

    Stamate, Eugen

    2014-01-01

    Dry processing based on reactive plasmas was the main driven force for micro- and recently nano-electronic industry. Once with the increasing in plasma complexity new diagnostics methods have been developed to ensure a proper process control during etching, thin film deposition, ion implantation...... or other steps in device fabrication. This work reviews some of the unconventional methods developed in the last two decays to measure the parameters of reactive plasmas including, the test function method, thermal probes, and plasma-sheath-lens probes. The negative ion detection and surface contamination...... in plasmas with a high degree of contamination are also addressed. (C) 2014 Elsevier B.V. All rights reserved....

  13. Imaging diagnostics in ovarian cancer

    DEFF Research Database (Denmark)

    Fog, Sigrid Marie Kasper Kasper; Dueholm, Margit; Marinovskij, Edvard;

    2017-01-01

    OBJECTIVE: To analyze the ability of magnetic resonance imaging (MRI) and systematic evaluation at surgery to predict optimal cytoreduction in primary advanced ovarian cancer and to develop a preoperative scoring system for cancer staging. STUDY DESIGN: Preoperative MRI and standard laparotomy were...... performed in 99 women with either ovarian or primary peritoneal cancer. Using univariate and multivariate logistic regression analysis of a systematic description of the tumor in nine abdominal compartments obtained by MRI and during surgery plus clinical parameters, a scoring system was designed....... MRI is able to assess ovarian cancer with peritoneal carcinomatosis with satisfactory concordance with laparotomic findings. This scoring system could be useful as a clinical guideline and should be evaluated and developed further in larger studies....

  14. Workshop on extremely high energy density plasmas and their diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Ishii, Shozo (ed.)

    2001-09-01

    Compiled are the papers presented at the workshop on 'Extremely High Energy Density Plasmas and Their Diagnostics' held at National Institute for Fusion Science. The papers cover physics and applications of extremely high-energy density plasmas such as dense z-pinch, plasma focus, and intense pulsed charged beams. Separate abstracts were presented for 7 of the papers in this report. The remaining 25 were considered outside the subject scope of INIS. (author)

  15. Marketing considerations for diagnostic imaging centers.

    Science.gov (United States)

    McCue, P

    1987-10-01

    Diagnostic imaging centers seek every possible advantage to maintain a successful practice in the face of competition from hospitals and other freestanding operators. Several radiologists and business managers involved in existing or planned centers discuss their marketing strategies, modality choices, organizational structure, and other issues pertinent to the start-up and operation of a viable free-standing operation.

  16. Irradiation effects on plasma diagnostic components

    Energy Technology Data Exchange (ETDEWEB)

    Nishitani, Takeo [ed.] [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment; Iida, Toshiyuki; Ikeda, Yujiro [and others

    1998-10-01

    One of the most important issues to develop the diagnostics for the experimental thermonuclear reactor such as ITER is the irradiation effects on the diagnostics components. Typical neutron flux and fluence on the first wall are 1 MW/m{sup 2} and 1 MWa/m{sup 2}, respectively for ITER. In such radiation condition, most of the present diagnostics could not survive so that those will be planed to be installed far from the vacuum vessel. However, some diagnostics sensors such as bolometers and magnetic probes still have to be install inside vessel. And many transmission components for lights, wave and electric signals are inevitable even inside vessel. As a part of this R and D program of the ITER Engineering Design Activities (EDA), we carried out the irradiation tests on the basic materials of the transmission components and in-vessel diagnostics sensors in order to identify radiation hardened materials that can be used for diagnostic systems. (J.P.N.)

  17. Laser-aided diagnostics of plasmas and gases

    CERN Document Server

    Muraoka, K

    2000-01-01

    Updated and expanded from the original Japanese edition, Laser-Aided Diagnostics of Gases and Plasmas takes a unique approach in treating laser-aided diagnostics. The book unifies the subject by joining applications instead of describing each application as a totally separate system. In taking this approach, it highlights the relative strengths of each method and shows how they can complement each other in the study of gases and plasmas.The first part of the book presents a general introduction to the laser-aided study of gases and plasmas, including the various principles and hardware needed for each method, while the second part describes the applications of each general system in detail.Beneficial to a wide spectrum of academic and industrial researchers, this book provides a solid examination of the various options and methods available when involved in the analysis and diagnostics of gases and plasmas.

  18. Spectra of neutral carbon for plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J.G.; Kato, M.; Kato, T.

    2000-10-01

    Recently, carbon pellet experiments have been performed on W-7AS and a few CI lines have been observed in the situation of the pellet cloud from the cold dense plasma to hot ambient plasma. In so large varied conditions, the collisional radiative (CR) model is needed to study the spectra. In this article, a CR model including 79 states with n {<=} 6 and l {<=} 4 is developed, and then the line spectra and line intensity ratios are evaluated in the ionizing and recombining plasma, respective. (author)

  19. Diagnostics in ? helicon plasmas for ? deposition

    Science.gov (United States)

    Granier, A.; Nicolazo, F.; Vallée, C.; Goullet, A.; Turban, G.; Grolleau, B.

    1997-05-01

    0963-0252/6/2/008/img3 and 0963-0252/6/2/008/img4 helicon plasmas used for plasma enhanced chemical vapour deposition of 0963-0252/6/2/008/img5 films are investigated in the 1 - 10 mTorr pressure and 0 - 800 W rf power ranges. The positive oxygen ions are analysed by energy selective mass spectrometry and Langmuir probes. The oxygen atom concentration is monitored by actinometry and ionization threshold mass spectrometry. In oxygen plasmas it is shown that 0963-0252/6/2/008/img6 is the major positive ion, and that the oxygen molecules are far from being completely dissociated, due to a very high oxygen atom recombination frequency on the reactor walls. The dissociation degree increases with the rf power reaching 10% at 500 W. In 0963-0252/6/2/008/img4 plasmas, the plasma density and electron temperature decrease as the TEOS fraction increases. In contrast, the degree of oxygen dissociation increases sharply with the addition of a few per cent TEOS, is maximum for about 5% TEOS and decreases as TEOS fraction is further increased. In a 95:5 0963-0252/6/2/008/img4 plasma (5 mTorr, 300 W) the fluxes of oxygen positive ions and atoms impinging onto a floating substrate are estimated to be 0963-0252/6/2/008/img9 and 0963-0252/6/2/008/img10 respectively. Under these plasma conditions, near-stoichiometric 0963-0252/6/2/008/img11 films, with low OH content, are deposited at ambient temperature. The corresponding atom to ion flux ratio is about 250, which suggests the dominant role of oxygen atoms in the deposition kinetics. The comparison of the compositions of layers grown in a 5 mTorr 95:5 0963-0252/6/2/008/img4 plasma at two rf powers confirms the major role of oxygen atoms.

  20. Status and challenges in electrical diagnostics of processing plasmas

    DEFF Research Database (Denmark)

    Stamate, Eugen

    Reactive plasmas produced in oxygen, nitrogen, hydrogen and other complex gas mixture are used for various applications including thin films, etching, ion implantation, ashing, particles growth, oxidation and other surface functionalization processes. Most of the reactive gases are also...... the possibility to control and use these plasmas for processing. Development of reactive plasma sources for both applications and basic science is rather challenging and some of these efforts will be presented in direct correlation with diagnostic approaches....... electronegative so that, the role of negative ions cannot be neglected. The continuous decrease of the features size in micro- and nanoelectronic industry requires a precise control of plasma parameters including the negative ions. Despite of a good progress in plasma diagnostics, yet more is to be done...

  1. No diagnostic value of plasma clusterin in Alzheimer's disease.

    Directory of Open Access Journals (Sweden)

    Edina Silajdžić

    Full Text Available There is an urgent need for biomarkers to enable early diagnosis of Alzheimer's disease (AD. It has recently been shown that a variant within the clusterin gene is associated with increased risk of AD and plasma levels of clusterin have been found to be associated with the risk of AD. We, therefore, investigated the diagnostic value of clusterin by quantifying clusterin using an ELISA in plasma from 171 controls, 127 patients with AD, 82 patients with other dementias and 30 patients with depression. We observed similar plasma clusterin levels in controls, AD patients and patients with other dementias, suggesting that plasma clusterin levels have no diagnostic value for AD. There was a slight, but significant, increase in plasma clusterin in patients with depression compared to all other groups tested, which may warrant further investigation.

  2. Optical diagnostics of femtosecond laser plasmas

    Institute of Scientific and Technical Information of China (English)

    LI; Yutong

    2001-01-01

    [1]Benattar, R., Popovics, C., Sigel, R., Polarized light interferometer for laser fusion studies, Rev. Sci. Instrum., 979, 50(2): 583.[2]Young, P. E., Hammer, J. H., Wilks, S. C. et al., Laser beam propagation and channel formation in underdense plasmas, Phys. Plasmas, 995, 2(7): 2825.[3]Zhang, P., He, J.T., Chen, D.B. et al., Effects of a prepulse on γ-ray radiation produced by a femtosecond laser with only mJ energy, Phys. Rev. E., 998, 57: R3746.[4]Stamper, J. A., Review on spontaneous magnetic fields in laser-produced plasmas: phenomena and measurements, Laser and Particle Beams, 99, 9(4): 84.[5]Stamper, J. A., McLean, E. A., Ripin, B. H., Studies of spontaneous magnetic fields in laser-produced plasmas by Faraday rotation, Phys. Rev. Lett., 978, 40(8): 77.[6]Raven, A., Willi, O., Rumsby, P. T., Megagauss magnetic field profiles in laser-produced plasmas, Phys. Rev. Lett., 978, 4(8): 554.[7]Burgess, M. D. J., Luther-Davis, B., Nugent, K. A., An experimental study of magnetic fields in plasmas created by high intensity one micron laser radiation, Phys. Fluids, 985, 28(7): 2286.[8]Borghesi, M., Mackinnon, A. J., Bell, A. R. et al., Megagauss magnetic field generation and plasma jet formation on solid targets irradiated by an ultraintense picosecond laser pulse, Phys. Rev. Lett., 998, 8(): 2.

  3. Physicians' use of plasma methylmalonic acid as a diagnostic tool

    DEFF Research Database (Denmark)

    Hvas, A M; Vestergaard, H; Gerdes, Lars Ulrik;

    2000-01-01

    : This lack of response to an increased plasma methylmalonic acid raises an important question. Is the clinical response inadequate, or is the connection between an increased level of plasma methylmalonic acid and signs of clinical significant cobalamin deficiency less clear?......OBJECTIVES: To investigate physicians' reasons for requesting plasma methylmalonic acid and their reactions to an increased concentration of plasma methylmalonic acid. DESIGN: Study of medical records. SETTING: Three somatic district hospitals in Denmark. SUBJECTS: Medical records of 198 patients...... with a plasma methylmalonic acid measurement above the reference interval. Information on diagnostic decisions was available for 177 patients. MAIN OUTCOME MEASURES: Reasons for requesting plasma methylmalonic acid and the reactions to the finding of elevated plasma methylmalonic acid. RESULTS: An explicit...

  4. Microwave-plasma interactions studied via mode diagnostics in ALPHA

    Science.gov (United States)

    Friesen, T.; Andresen, G. B.; Ashkezari, M. D.; Baquero-Ruiz, M.; Bertsche, W.; Bowe, P. D.; Butler, E.; Cesar, C. L.; Chapman, S.; Charlton, M.; Eriksson, S.; Fajans, J.; Fujiwara, M. C.; Gill, D. R.; Gutierrez, A.; Hangst, J. S.; Hardy, W. N.; Hayano, R. S.; Hayden, M. E.; Humphries, A. J.; Hydomako, R.; Jonsell, S.; Kurchaninov, L.; Madsen, N.; Menary, S.; Nolan, P.; Olchanski, K.; Olin, A.; Povilus, A.; Pusa, P.; Robicheaux, F.; Sarid, E.; Silveira, D. M.; So, C.; Storey, J. W.; Thompson, R. I.; van der Werf, D. P.; Wurtele, J. S.; Yamazaki, Y.

    The goal of the ALPHA experiment is the production, trapping and spectroscopy of antihydrogen. A direct comparison of the ground state hyperfine spectra in hydrogen and antihydrogen has the potential to be a high-precision test of CPT symmetry. We present a novel method for measuring the strength of a microwave field for hyperfine spectroscopy in a Penning trap. This method incorporates a non-destructive plasma diagnostic system based on electrostatic modes within an electron plasma. We also show how this technique can be used to measure the cyclotron resonance of the electron plasma, which can potentially serve as a non-destructive measurement of plasma temperature.

  5. Diagnostic imaging of craniopharyngioma; Diagnostyka obrazowa czaszkogardlakow

    Energy Technology Data Exchange (ETDEWEB)

    Gradzki, J.; Nowak, S.; Paprzycki, W. [Akademia Medyczna, Poznan (Poland)

    1993-12-31

    40 patients have been examined with operational and histological confirmation of craniopharyngioma. CT image and X-ray plane of skull were performed in case all of these patients. TMR was conformed to examine 4 patients. X-ray planes was compared to CT. CT permits tumor cyst detection. The efficacy of mentioned above diagnostic techniques was compared with surgical findings. (author). 7 refs, 5 figs, 2 tabs.

  6. Recent results on ITER plasma equilibrium diagnostics and identification

    Energy Technology Data Exchange (ETDEWEB)

    Albanese, R.; Coccorese, E.; Morabito, F.C.; Pironti, A.; Versaci, M. [Associazione CREATE/ENEA/EURATOM - DIMET, Loc. Feo di Vito, Reggio Calabria (Italy); Mc Carthy, P.J. [Cork Univ. College (Ireland). Physics Dept.

    1998-07-01

    The most recent results achieved by our work-group on the plasma shape and position identification problem as well as on the interpretation of magnetic diagnostics are presented. The proposed test cases are related to the most recent configuration of sensors and geometry specification available from ITER. One of the aims of the work is also to give some design directions about the problem of optimal selection of the diagnostics for control parameters. (author)

  7. Vertical Electron Cyclotron Emission Diagnostic for TCV Plasmas

    Directory of Open Access Journals (Sweden)

    Goodman T. P.

    2012-09-01

    Full Text Available Electron cyclotron resonance heating (ECRH and electron cyclotron current drive (ECCD are used to heat the plasma, to tailor the current profiles and to achieve different operating regimes of tokamak plasmas. Plasmas with ECRH/ECCD are characterized by non-thermal electrons, which cannot be described by a Maxwellian distribution. Non-thermal electrons are also generated during MHD activity, like sawteeth crashes. Quantifying the non-thermal electron distribution is therefore a key for understanding EC heated fusion plasmas. For this purpose a vertical electron cyclotron emission (V-ECE diagnostic is being installed at TCV. The diagnostic layout, the calibration, the analysis technique for data interpretation, the physics potentials and limitations are discussed.

  8. Plasma diagnostics using synchrotron radiation in tokamaks

    Energy Technology Data Exchange (ETDEWEB)

    Fidone, I.; Giruzzi, G.; Granata, G.

    1995-09-01

    This report deal with the use of synchrotron radiation in tokamaks. The main advantage of this new method is that it enables to overcome several deficiencies, caused by cut-off, refraction, and harmonic overlap. It also makes it possible to enhance the informative contents of the familiar low harmonic scheme. The basic theory of the method is presented and illustrated by numerical applications, for plasma parameters of relevance in present and next step tokamaks. (TEC). 10 refs., 13 figs.

  9. Signal processing methods for MFE plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Candy, J.V.; Casper, T.; Kane, R.

    1985-02-01

    The application of various signal processing methods to extract energy storage information from plasma diamagnetism sensors occurring during physics experiments on the Tandom Mirror Experiment-Upgrade (TMX-U) is discussed. We show how these processing techniques can be used to decrease the uncertainty in the corresponding sensor measurements. The algorithms suggested are implemented using SIG, an interactive signal processing package developed at LLNL.

  10. Flush-mounted probe diagnostics for argon glow discharge plasma

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Liang, E-mail: xld02345@mail.ustc.edu.cn; Cao, Jinxiang; Liu, Yu; Wang, Jian; Du, Yinchang; Zheng, Zhe; Zhang, Xiao; Wang, Pi [Department of Modern Physics, University of Science and Technology of China, Hefei, Anhui 230026 (China); Zhang, Jin; Li, Xiao; Qin, Yongqiang; Zhao, Liang [Science and Technology on Space Physics Laboratory, Beijing 100076 (China)

    2014-09-15

    A comparison is made between plasma parameters measured by a flush-mounted probe (FP) and a cylindrical probe (CP) in argon glow discharge plasma. Parameters compared include the space potential, the plasma density, and the effective electron temperature. It is found that the ion density determined by the FP agrees well with the electron density determined by the CP in the quasi-neutral plasma to better than 10%. Moreover, the space potential and effective electron temperature calculated from electron energy distribution function measured by the FP is consistent with that measured by the CP over the operated discharge current and pressure ranges. These results present the FP can be used as a reliable diagnostic tool in the stable laboratory plasma and also be anticipated to be applied in other complicated plasmas, such as tokamaks, the region of boundary-layer, and so on.

  11. Simultaneous imaging/reflectivity measurements to assess diagnostic mirror cleaninga)

    Science.gov (United States)

    Skinner, C. H.; Gentile, C. A.; Doerner, R.

    2012-10-01

    Practical methods to clean ITER's diagnostic mirrors and restore reflectivity will be critical to ITER's plasma operations. We describe a technique to assess the efficacy of mirror cleaning techniques and detect any damage to the mirror surface. The method combines microscopic imaging and reflectivity measurements in the red, green, and blue spectral regions and at selected wavelengths. The method has been applied to laser cleaning of single crystal molybdenum mirrors coated with either carbon or beryllium films 150-420 nm thick. It is suitable for hazardous materials such as beryllium as the mirrors remain sealed in a vacuum chamber.

  12. Simultaneous imaging/reflectivity measurements to assess diagnostic mirror cleaning.

    Science.gov (United States)

    Skinner, C H; Gentile, C A; Doerner, R

    2012-10-01

    Practical methods to clean ITER's diagnostic mirrors and restore reflectivity will be critical to ITER's plasma operations. We describe a technique to assess the efficacy of mirror cleaning techniques and detect any damage to the mirror surface. The method combines microscopic imaging and reflectivity measurements in the red, green, and blue spectral regions and at selected wavelengths. The method has been applied to laser cleaning of single crystal molybdenum mirrors coated with either carbon or beryllium films 150-420 nm thick. It is suitable for hazardous materials such as beryllium as the mirrors remain sealed in a vacuum chamber.

  13. Diagnostics and results from coaxial plasma gun development for the PLX- α project

    Science.gov (United States)

    Case, A.; Brockington, S.; Cruz, E.; Witherspoon, F. D.

    2016-10-01

    We present results from the diagnostics used during development of the contoured gap coaxial plasma guns for the PLX- α project at LANL. Plasma-jet diagnostics include fast photodiodes for velocimetry, a ballistic pendulum for total plasmoid momentum, and interferometry for line integrated density. Deflectometry will be used for line integrated perpendicular density gradients. Time-resolved high-resolution spectroscopy using a novel detector and time-integrated survey spectroscopy are used for measurements of velocity and temperature, as well as impurities. We will also use a Faraday cup for density, fast imaging for plume geometry, and time-integrated imaging for overall light emission. Experimental results are compared to the desired target parameters for the plasma jets (up to n 2 ×1016cm-3 , v 50km / s , mass 5gm , radius = 4cm , and length 10cm). This work supported by the ARPA-E ALPHA Program.

  14. Ultrafast Diagnostics for Electron Beams from Laser Plasma Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Matlis, N. H.; Bakeman, M.; Geddes, C. G. R.; Gonsalves, T.; Lin, C.; Nakamura, K.; Osterhoff, J.; Plateau, G. R.; Schroeder, C. B.; Shiraishi, S.; Sokollik, T.; van Tilborg, J.; Toth, Cs.; Leemans, W. P.

    2010-06-01

    We present an overview of diagnostic techniques for measuring key parameters of electron bunches from Laser Plasma Accelerators (LPAs). The diagnostics presented here were chosen because they highlight the unique advantages (e.g., diverse forms of electromagnetic emission) and difficulties (e.g., shot-to-shot variability) associated with LPAs. Non destructiveness and high resolution (in space and time and energy) are key attributes that enable the formation of a comprehensive suite of simultaneous diagnostics which are necessary for the full characterization of the ultrashort, but highly-variable electron bunches from LPAs.

  15. Plasma-driven ultrashort bunch diagnostic

    CERN Document Server

    Dornmair, I; Floettmann, K; Marchetti, B; Maier, A R

    2016-01-01

    Ultrashort electron bunches are crucial for an increasing number of applications, however, diagnosing their longitudinal phase space remains a challenge. We propose a new method that harnesses the strong electric fields present in a laser driven plasma wakefield. By transversely displacing driver laser and witness bunch, a streaking field is applied to the bunch. This field maps the time information to a transverse momentum change and, consequently, to a change of transverse position. We illustrate our method with simulations where we achieve a time resolution in the attosecond range.

  16. Plasma-driven ultrashort bunch diagnostics

    Science.gov (United States)

    Dornmair, I.; Schroeder, C. B.; Floettmann, K.; Marchetti, B.; Maier, A. R.

    2016-06-01

    Ultrashort electron bunches are crucial for an increasing number of applications, however, diagnosing their longitudinal phase space remains a challenge. We propose a new method that harnesses the strong electric fields present in a laser driven plasma wakefield. By transversely displacing driver laser and witness bunch, a streaking field is applied to the bunch. This field maps the time information to a transverse momentum change and, consequently, to a change of transverse position. We illustrate our method with simulations where we achieve a time resolution in the attosecond range.

  17. Active imaging for monitoring and technical diagnostics

    Directory of Open Access Journals (Sweden)

    Marek Piszczek

    2014-08-01

    Full Text Available The article presents the results of currently running work in the field of active imaging. The term active refers to both the image acquisition methods, so-called methods of the spatio-temporal framing and active visualization method applying augmented reality. Also results of application of the HMD and 6DoF modules as well as the experimental laser photography device are given. The device works by methods of spatio-temporal framing and it has been developed at the IOE WAT. In terms of image acquisition - active imaging involves the use of illumination of the observed scene. In the field of information visualization - active imaging directly concerns the issues of interaction human-machine environment. The results show the possibility of using the described techniques, among others, rescue (fire brigade, security of mass events (police or the protection of critical infrastructure as well as broadly understood diagnostic problems. Examples presented in the article show a wide range of possible uses of the methods both in observational techniques and measurement. They are relatively innovative solutions and require elaboration of series of hardware and algorithmic issues. However, already at this stage it is clear that active acquisition and visualization methods indicate a high potential for this type of information solutions.[b]Keywords[/b]: active imaging, augmented reality, digital image processing

  18. Image enhancement of digital periapical radiographs according to diagnostic tasks

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jin Woo; Han, Won Jeong; Kim, Eun Kyung [Dept. of Oral and Maxillofacial Radiology, Dankook University College of Dentistry, Cheonan (Korea, Republic of)

    2014-03-15

    his study was performed to investigate the effect of image enhancement of periapical radiographs according to the diagnostic task. Eighty digital intraoral radiographs were obtained from patients and classified into four groups according to the diagnostic tasks of dental caries, periodontal diseases, periapical lesions, and endodontic files. All images were enhanced differently by using five processing techniques. Three radiologists blindly compared the subjective image quality of the original images and the processed images using a 5-point scale. There were significant differences between the image quality of the processed images and that of the original images (P<0.01) in all the diagnostic task groups. Processing techniques showed significantly different efficacy according to the diagnostic task (P<0.01). Image enhancement affects the image quality differently depending on the diagnostic task. And the use of optimal parameters is important for each diagnostic task.

  19. Polarizer design for millimeter-wave plasma diagnostics

    DEFF Research Database (Denmark)

    Leipold, Frank; Salewski, Mirko; Jacobsen, Asger Schou

    2013-01-01

    Radiation from magnetized plasmas is in general elliptically polarized. In order to convert the elliptical polarization to linear polarization, mirrors with grooved surfaces are currently employed in our collective Thomson scattering diagnostic at ASDEX Upgrade. If these mirrors can be substituted...

  20. Near-infrared spectroscopy for burning plasma diagnostic applications.

    Science.gov (United States)

    Soukhanovskii, V A

    2008-10-01

    Ultraviolet and visible (UV-VIS, 200-750 nm) atomic spectroscopy of neutral and ionized fuel species (H, D, T, and Li) and impurities (e.g., He, Be, C, and W) is a key element of plasma control and diagnosis on International Thermonuclear Experimental Reactor and future magnetically confined burning plasma experiments (BPXs). Spectroscopic diagnostic implementation and performance issues that arise in the BPX harsh nuclear environment in the UV-VIS range, e.g., degradation of first mirror reflectivity under charge-exchange atom bombardment (erosion) and impurity deposition, permanent and dynamic loss of window, and optical fiber transmission under intense neutron and gamma-ray fluxes, are either absent or not as severe in the near-infrared (NIR, 750-2000 nm) range. An initial survey of NIR diagnostic applications has been undertaken on the National Spherical Torus Experiment. It is demonstrated that NIR spectroscopy can be used for machine protection and plasma control applications, as well as contribute to plasma performance evaluation and physics studies. Emission intensity estimates demonstrate that NIR measurements are possible in the BPX plasma operating parameter range. Complications in the NIR range due to the parasitic background emissions are expected to occur at very high plasma densities, low impurity densities, and at high plasma-facing component temperatures.

  1. Quantitative single shot and spatially resolved plasma wakefield diagnostics

    CERN Document Server

    Kasim, Muhammad Firmansyah; Ceurvorst, Luke; Levy, Matthew C; Ratan, Naren; Sadler, James; Bingham, Robert; Burrows, Philip N; Trines, Raoul; Wing, Matthew; Norreys, Peter

    2015-01-01

    Diagnosing plasma conditions can give great advantages in optimizing plasma wakefield accelerator experiments. One possible method is that of photon acceleration. By propagating a laser probe pulse through a plasma wakefield and extracting the imposed frequency modulation, one can obtain an image of the density modulation of the wakefield. In order to diagnose the wakefield parameters at a chosen point in the plasma, the probe pulse crosses the plasma at oblique angles relative to the wakefield. In this paper, mathematical expressions relating the frequency modulation of the laser pulse and the wakefield density profile of the plasma for oblique crossing angles are derived. Multidimensional particle-in-cell simulation results presented in this paper confirm that the frequency modulation profiles and the density modulation profiles agree to within 10%. Limitations to the accuracy of the measurement are discussed in this paper. This technique opens new possibilities to quantitatively diagnose the plasma wakefie...

  2. Advanced Plasma Diagnostic Analysis using Neural Networks

    Science.gov (United States)

    Tritz, Kevin; Reinke, Matt

    2016-10-01

    Machine learning techniques, specifically neural networks (NN), are used with sufficient internal complexity to develop an empirically weighted relationship between a set of filtered X-ray emission measurements and the electron temperature (Te) profile for a specific class of discharges on NSTX. The NN response matrix is used to calculate the Te profile directly from the filtered X-ray diode measurements which extends the electron temperature time response from the 60Hz Thomson Scattering profile measurements to fast timescales (>10kHz) and greatly expands the applicability of Te profile information to fast plasma phenomena, such as ELM dynamics. This process can be improved by providing additional information which helps the neural network refine the relationship between Te and the corresponding X-ray emission. NN supplement limited measurements of a particular quantity using related measurements with higher time or spatial resolution. For example, the radiated power (Prad) determined using resistive foil bolometers is related to similar measurements using AXUV diode arrays through a complex and slowly time-evolving quantum efficiency curve in the VUV spectral region. Results from a NN trained using Alcator C-Mod resistive foil bolometry and AXUV diodes are presented, working towards hybrid Prad measurements with the quantitative accuracy of resistive foil bolometers and with the enhanced temporal and spatial resolution of the unfiltered AXUV diode arrays. Work supported by Department of Energy Grant #: DE-FG02-09ER55012.

  3. Papers presented at the eleventh topical conference on high-temperature plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report contains the following eleven papers presented at the conference: Neutral Beam Diagnostics for Alcator C-Mod; A Study for the Installation of the TEXT HIBP on DIII-D; Time-domain Triple-probe Measurement of Edge Plasma Turbulence on TEXT-U; A Langmuir/Mach Probe Array for Edge Plasma Turbulence and Flow; Determination of Field Line Location and Safety Factor in TEXT-U; Hybrid ECE Imaging Array System for TEXT-U; First Results from the Phase Contrast Imaging System on TEXT-U; A Fast Tokamak Plasma Flux and Electron Density Reconstruction Technique; Time-series Analysis of Nonstationary Plasma Fluctuations Using Wavelet Transforms; Quantitative Modeling of 3-D Camera Views for Tokamak Divertors; and Variable-frequency Complex Demodulation Technique for Extracting Amplitude and Phase Information. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  4. Plasma diagnostics by means of electric probes; Diagnostico del plasma por medio de sondas electricas

    Energy Technology Data Exchange (ETDEWEB)

    Colunga S, S

    1991-04-15

    In this work a summary of the classical theoretical models to interpret the characteristic curve of a Langmuir electric probe placed in a plasma without magnetic field and with the one is made. The methodology for the electron temperature calculation and the density of the plasma in both cases is given, starting from the characteristic curve of the probe, as well as the approaches for the correct application of this diagnostic method of the plasma. (Author)

  5. Usefulness of diagnostic imaging in primary hyperparathyroidism

    Energy Technology Data Exchange (ETDEWEB)

    Sekiyama, Kazuya; Akakura, Koichiro; Mikami, Kazuo; Mizoguchi, Ken-ichi; Tobe, Toyofusa; Nakano, Koichi; Numata, Tsutomu; Konno, Akiyoshi; Ito, Haruo [Chiba Univ. (Japan). Graduate School of Medicine

    2003-01-01

    In patients with primary hyperparathyroidism, prevention of urinary stone recurrence can be achieved by surgical removal of the enlarged parathyroid gland. To ensure the efficacy of surgery for primary hyperparathyroidism, preoperative localization of the enlarged gland is important. In the present study, usefulness of diagnostic imaging for localization of the enlarged gland was investigated in primary hyperparathyroidism. We retrospectively examined the findings of imaging studies and clinical records in 79 patients (97 glands) who underwent surgical treatment for primary hyperparathyroidism at Chiba University Hospital between 1976 and 2000. The detection rates of accurate localization were investigated for imaging techniques, such as ultrasonography (US), computed tomography (CT), magnetic resonance imaging (MRI) thallium-201 and technetium-99m pertechnetate (Tl-Tc) subtraction scintigraphy and {sup 99m}Tc-methoxyisobutylisonitrile (MIBI) scintigraphy, and analysed in relation to the size and weight of the gland and pathological diagnosis. The detection rates by US, CT, MRI, Tl-Tc subtraction scintigraphy and MIBI scintigraphy were 70%, 67%, 73%, 38% and 78%, respectively. The overall detection rate changed from 50% to 88% before and after 1987. The detection rate of MIBI scintigraphy was superior to Tl-Tc subtraction scintigraphy. In primary hyperparathyroidism, improvement of accurate localization of an enlarged parathyroid gland was demonstrated along with recent advances in imaging techniques including MIBI scintigraphy. (author)

  6. Cross-diagnostic comparison of fluctuation measurements in a linear plasma column

    Science.gov (United States)

    Light, Adam D.; Archer, Nicholas A. A.; Bashyal, Atit; Chakraborty Thakur, Saikat; Tynan, George R.

    2015-11-01

    The advent of fast imaging diagnostics, which provide two-dimensional measurements on relevant plasma time scales, has proven invaluable for interpreting plasma dynamics in laboratory devices. Despite its success, imaging remains a qualitative aid for many studies, because intensity is difficult to map onto a single physical variable for use in a theoretical model. This work continues our exploration of the relationship between visible-light and electrostatic probe measurements in the Controlled Shear Decorrelation Experiment (CSDX). CSDX is a well-characterized linear machine producing dense plasmas relevant to the tokamak edge (Te ~ 3 eV, ne ~1013 /cc). Visible light from ArI and ArII line emission is collected at high frame rates using a fast digital camera. Floating potential and ion-saturation current are measured by an array of electrostatic probe tips. We present a detailed comparison between imaging and probe measurements of fluctuations, including temporal, spatial, and spectral properties in various operational regimes.

  7. SXR-XUV Diagnostics for Edge and Core of Magnetically Confined Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Stutman, Dan [Johns Hopkins University

    2014-09-10

    The present report summarizes the results obtained during a one-year extension of DoE grant “SXR-XUV Diagnostics for Edge and Core of Magnetically Confined Plasmas”, at Johns Hopkins University, aimed at completing the development of a new type of magnetic fusion plasma diagnostic, the XUV Transmission Grating Imaging Radiometer (TGIR). The TGIR enables simultaneous spatially and spectrally resolved measurements of the XUV/VUV radiated power from impurities in fusion plasmas, with high speed. The instrument was successfully developed and qualified in the laboratory and in experiments on a tokamak. Its future applications will be diagnostic of the impurity content and transport in the divertor and edge of advanced magnetic fusion experiments, such as NSTX Upgrade.

  8. Evaluation of image uniformity in diagnostic magnetic resonance images

    Energy Technology Data Exchange (ETDEWEB)

    Ogura, Akio [Kyoto City Hospital (Japan); Inoue, Hiroshi; Higashida, Mitsuji; Yamazaki, Masaru; Uto, Tomoyuki

    1997-12-01

    Image uniformity refers to the ability of the MR imaging system to produce a constant signal response throughout the scanned volume when the object being imaged has homogeneous MR characteristics. To facilitate the determination of image uniformity in diagnostic magnetic resonance images, reports such as the NEMA Standard and AAPM report have been issued. However, these methods of evaluation are impractical in cases such as the day-to-day quality control of the machine or comparisons between the different MR systems, because these methods affect the signal-to-noise ratio (SNR) and create problems by displaying nonuniformity locations. Therefore, we present a new method for evaluating uniformity, called the test segment method. The influence of SNR on the NEMA test and the segment method were examined. In addition, the results of the two methods were compared for certain nonuniformity conditions. Results showed that the segment method did not affect SNR and provided good display of nonuniformity. (author)

  9. Synthetic plasma edge diagnostics for EMC3-EIRENE, highlighted for Wendelstein 7-X

    Science.gov (United States)

    Frerichs, H.; Effenberg, F.; Schmitz, O.; Biedermann, C.; Feng, Y.; Jakubowski, M.; König, R.; Krychowiak, M.; Lore, J.; Niemann, H.; Pedersen, T. S.; Stephey, L.; Wurden, G. A.

    2016-11-01

    Interpretation of spectroscopic measurements in the edge region of high-temperature plasmas can be a challenge since line of sight integration effects make direct interpretation in terms of quantitative, local emission strengths often impossible. The EMC3-EIRENE code—a 3D fluid edge plasma and kinetic neutral gas transport code—is a suitable tool for full 3D reconstruction of such signals. A versatile synthetic diagnostic module has been developed recently which allows the realistic 3D setup of various plasma edge diagnostics to be captured. We highlight these capabilities with two examples for Wendelstein 7-X (W7-X): a visible camera for the analysis of recycling, and a coherent-imaging system for velocity measurements.

  10. Biomedical applications and diagnostics of atmospheric pressure plasma

    Science.gov (United States)

    Petrović, Z. Lj; Puač, N.; Lazović, S.; Maletić, D.; Spasić, K.; Malović, G.

    2012-03-01

    Numerous applications of non-equilibrium (cold, low temperature) plasmas require those plasmas to operate at atmospheric pressure. Achieving non-equilibrium at atmospheric pressure is difficult since the ionization growth is very fast at such a high pressure. High degree of ionization on the other hand enables transfer of energy between electrons and ions and further heating of the background neutral gas through collisions between ions and neutrals. Thus, all schemes to produce non-equilibrium plasmas revolve around some form of control of ionization growth. Diagnostics of atmospheric pressure plasmas is difficult and some of the techniques cannot be employed at all. The difficulties stem mostly from the small size. Optical emission spectroscopy and laser absorption spectroscopy require very high resolution in order to resolve the anatomy of the discharges. Mass analysis is not normally applicable for atmospheric pressure plasmas, but recently systems with triple differential pumping have been developed that allow analysis of plasma chemistry at atmospheric pressures which is essential for numerous applications. Application of such systems is, however, not free from problems. Applications in biomedicine require minimum heating of the ambient air. The gas temperature should not exceed 40 °C to avoid thermal damage to the living tissues. Thus, plasmas should operate at very low powers and power control is essential. We developed unique derivative probes that allow control of power well below 1 W and studied four different sources, including dielectric barrier discharges, plasma needle, atmospheric pressure jet and micro atmospheric pressure jet. The jet operates in plasma bullet regime if proper conditions are met. Finally, we cover results on treatment of bacteria and human cells as well as treatment of plants by plasmas. Localized delivery of active species by plasmas may lead to a number of medical procedures that may also involve removal of bacteria, fungi and

  11. Diagnostic Suite for HyperV Coaxial Plasma Gun Development for the PLX- α Project

    Science.gov (United States)

    Case, Andrew; Brockington, Sam; Witherspoon, F. Douglas

    2015-11-01

    We present the diagnostic suite to be used during development of the coaxial guns HyperV will deliver to LANL in support of the ARPA-E Accelerating Low-Cost Plasma Heating And Assembly (ALPHA) program. For plasma jet diagnostics this includes fast photodiodes for velocimetry, a ballistic pendulum for measuring total plasmoid momentum, interferometry for line integrated plasma density, deflectometry for line integrated perpendicular density gradient measurements, and spectroscopy, both time resolved high resolution spectroscopy using a novel detector developed by HyperV and time integrated survey spectroscopy, for measurements of velocity and temperature as well as impurities. In addition, we plan to use fast pressure probes for stagnation pressure, a Faraday cup for density, fast imaging for plume geometry and time integrated imaging for overall light emission. A novel low resolution long record length camera developed by HyperV will also be used for plume diagnostics. For diagnostics of gun operation, we will use Rogowski coils to measure current, voltage dividers for voltages, B-dot probes for magnetic field, and time resolved fast photodiodes to measure plasmoid velocity inside the accelerator. This work supported by the ARPA-E ALPHA program.

  12. Evaluation of two-beam spectroscopy as a plasma diagnostic

    Energy Technology Data Exchange (ETDEWEB)

    Billard, B.D.

    1980-04-01

    A two-beam spectroscopy (TBS) system is evaluated theoretically and experimentally. This new spectroscopic technique uses correlations between components of emitted light separated by a small difference in angle of propagation. It is thus a non-perturbing plasma diagnostic which is shown to provide local (as opposed to line-of-sight averaged) information about fluctuations in the density of light sources within a plasma - information not obtainable by the usual spectroscopic methods. The present design is an improvement on earlier systems proposed in a thesis by Rostler.

  13. Remote network control plasma diagnostic system for Tokamak T-10

    Science.gov (United States)

    Troynov, V. I.; Zimin, A. M.; Krupin, V. A.; Notkin, G. E.; Nurgaliev, M. R.

    2016-09-01

    The parameters of molecular plasma in closed magnetic trap is studied in this paper. Using the system of molecular diagnostics, which was designed by the authors on the «Tokamak T-10» facility, the radiation of hydrogen isotopes at the plasma edge is investigated. The scheme of optical radiation registration within visible spectrum is described. For visualization, identification and processing of registered molecular spectra a new software is developed using MatLab environment. The software also includes electronic atlas of electronic-vibrational-rotational transitions for molecules of protium and deuterium. To register radiation from limiter cross-section a network control system is designed using the means of the Internet/Intranet. Remote control system diagram and methods are given. The examples of web-interfaces for working out equipment control scenarios and viewing of results are provided. After test run in Intranet, the remote diagnostic system will be accessible through Internet.

  14. High-efficiency fast scintillators for "optical" soft x-ray arrays for laboratory plasma diagnostics.

    Science.gov (United States)

    Delgado-Aparicio, L F; Stutman, D; Tritz, K; Vero, R; Finkenthal, M; Suliman, G; Kaita, R; Majeski, R; Stratton, B; Roquemore, L; Tarrio, C

    2007-08-20

    Scintillator-based "optical" soft x-ray (OSXR) arrays have been investigated as a replacement for the conventional silicon (Si)-based diode arrays used for imaging, tomographic reconstruction, magnetohydrodynamics, transport, and turbulence studies in magnetically confined fusion plasma research. An experimental survey among several scintillator candidates was performed, measuring the relative and absolute conversion efficiencies of soft x rays to visible light. Further investigations took into account glass and fiber-optic face-plates (FOPs) as substrates, and a thin aluminum foil (150 nm) to reflect the visible light emitted by the scintillator back to the optical detector. Columnar (crystal growth) thallium-doped cesium iodide (CsI:Tl) deposited on an FOP, was found to be the best candidate for the previously mentioned plasma diagnostics. Its luminescence decay time of the order of approximately 1-10 micros is thus suitable for the 10 micros time resolution required for the development of scintillator-based SXR plasma diagnostics. A prototype eight channel OSXR array using CsI:Tl was designed, built, and compared to an absolute extreme ultraviolet diode counterpart: its operation on the National Spherical Torus Experiment showed a lower level of induced noise relative to the Si-based diode arrays, especially during neutral beam injection heated plasma discharges. The OSXR concept can also be implemented in less harsh environments for basic spectroscopic laboratory plasma diagnostics.

  15. Numerical calculation of charge exchange cross sections for plasma diagnostics

    Science.gov (United States)

    Mendez, Luis

    2016-09-01

    The diagnostics of impurity density and temperature in the plasma core in tokamak plasmas is carried out by applying the charge exchange recombination spectroscopy (CXRS) technique, where a fast beam of H atoms collides with the plasma particles leading to electron capture reactions with the impurity ions. The diagnostics is based on the emission of the excited ions formed in the electron capture. The application of the CXRS requires the knowledge of accurate state-selective cross sections, which in general are not accessible experimentally, and the calculation of cross sections for the high n capture levels, required for the diagnostics in the intermediate energy domain of the probe beam, is particularly difficult. In this work, we present a lattice numerical method to solve the time dependent Schrödinger equation. The method is based on the GridTDSE package, it is applicable in the wide energy range 1 - 500 keV/u and can be used to assess the accuracy of previous calculations. The application of the method will be illustrated with calculations for collisions of multiply charged ions with H. Work partially supported by project ENE2014-52432-R (Secretaria de Estado de I+D+i, Spain).

  16. Microwave and optical diagnostics in a gadolinium plasma; Diagnostics hyperfrequence et optique dans un plasma magnetise de gadolinium

    Energy Technology Data Exchange (ETDEWEB)

    Larousse, B. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. des Procedes d`Enrichissement]|[Conservatoire National des Arts et Metiers (CNAM), 75 - Paris (France)

    1997-12-31

    The optimization of the separation process of the gadolinium isotopes by Ion Cyclotron Resonance requires a precise knowledge of the physical characteristics of the plasma. Thus, two kinds of diagnostics have been developed: the first one to estimate the microwave power inside the source and the second one to measure the density of atomic and ionic of the gadolinium inside the plasma source and in front of the collector. Microwave diagnostic: A microstrip antenna has been designed and developed in order to characterize the microwave at 36 GHz frequency in the plasma source. The experimental results for different plasma regimes are presented. The measurements inside the plasma source show a maximum of microwave absorption for an argon pressure of 10{sup -4} mb (93% of absorption of the incident wave in the conditions of isotope separation). Laser absorption diagnostic: The theory of laser absorption in presence of a magnetic field is recalled and the first results are presented. In the spectral range between 560 and 620 nm, corresponding to high energy levels of gadolinium, no signal is obtained so that the density is below the detection limit 10{sup 10} cm{sup -3}. In the spectral range between 380 and 400 nm, two lines are observed, issue from the fundamental and metastable (633 cm{sup -1}) levels. The density of metastable level of gadolinium ions is about 10{sup 10} cm{sup -3} with a relative precision of 15 % and its variation is studied as a function of argon pressure, at different sections of the plasma column (source, collector). The achieved set of measurements has been performed in order to check the theoretical models. (author) 32 refs.

  17. OPTIMIZATION OF DIAGNOSTIC IMAGING IN BREAST CANCER

    Directory of Open Access Journals (Sweden)

    S. A. Velichko

    2015-01-01

    Full Text Available The paper presents the results of breast imaging for 47200 women. Breast cancer was detected in 862 (1.9% patients, fibroadenoma in 1267 (2.7% patients and isolated breast cysts in 1162 (2.4% patients. Different types of fibrocystic breast disease (adenosis, diffuse fibrocystic changes, local fibrosis and others were observed in 60.1% of women. Problems of breast cancer visualization during mammography, characterized by the appearance of fibrocystic mastopathy (sclerosing adenosis, fibrous bands along the ducts have been analyzed. Data on the development of diagnostic algorithms including the modern techniques for ultrasound and interventional radiology aimed at detecting early breast cancer have been presented.  

  18. Applying Quantum Cascade Laser Spectroscopy in Plasma Diagnostics

    Directory of Open Access Journals (Sweden)

    Jürgen Röpcke

    2016-07-01

    Full Text Available The considerably higher power and wider frequency coverage available from quantum cascade lasers (QCLs in comparison to lead salt diode lasers has led to substantial advances when QCLs are used in pure and applied infrared spectroscopy. Furthermore, they can be used in both pulsed and continuous wave (cw operation, opening up new possibilities in quantitative time resolved applications in plasmas both in the laboratory and in industry as shown in this article. However, in order to determine absolute concentrations accurately using pulsed QCLs, careful attention has to be paid to features like power saturation phenomena. Hence, we begin with a discussion of the non-linear effects which must be considered when using short or long pulse mode operation. More recently, cw QCLs have been introduced which have the advantage of higher power, better spectral resolution and lower fluctuations in light intensity compared to pulsed devices. They have proved particularly useful in sensing applications in plasmas when very low concentrations have to be monitored. Finally, the use of cw external cavity QCLs (EC-QCLs for multi species detection is described, using a diagnostics study of a methane/nitrogen plasma as an example. The wide frequency coverage of this type of QCL laser, which is significantly broader than from a distributed feedback QCL (DFB-QCL, is a substantial advantage for multi species detection. Therefore, cw EC-QCLs are state of the art devices and have enormous potential for future plasma diagnostic studies.

  19. Plasma characterization on carbon fiber cathode by spectroscopic diagnostics

    Institute of Scientific and Technical Information of China (English)

    Liu Lie; Li Li-Min; Xu Qi-Fu; Chang Lei; Wen Jian-Chun

    2009-01-01

    This paper mainly investigates plasma characterization on carbon fiber cathodes with and without cesium iodide (CsI) coating powered by a~300 ns,~200 kV accelerating pulse. It was found that the CsI layers can not only improve the diode voltage,but also maintain a stable perveance.This indicates a slowly changed diode gap or a low cathode plasma expansion velocity.By spectroscopic diagnostics,in the vicinity of the cathode surface the average plasma density and temperature were found to be~3×1014 cm-3 and~5 eV,respectively,for an electron current density of~40 A/cm2.Furthermore,there exists a multicomponent plasma expansion toward the anode.The plasma expansion velocity,corresponding to the carbon and hydrogen ions,is estimated to be~1.5 cm/μs.Most notably,Cs spectroscopic line was obtained only at the distance ≤0.5 mm from the cathode surface.Carbon and hydrogen ions are obtained up to the distance of 2.5 mm from the cathode surface.Cs ions almost remain at the vicinity of the cathode surface.These results show that the addition of Cal enables a slow cathode plasma expansion toward the anode,providing a positive prospect for developing long-pulse electron beam sources.

  20. Advanced targets, diagnostics and applications of laser-generated plasmas

    Science.gov (United States)

    Torrisi, L.

    2015-04-01

    High-intensity sub-nanosecond-pulsed lasers irradiating thin targets in vacuum permit generation of electrons and ion acceleration and high photon yield emission in non-equilibrium plasmas. At intensities higher than 1015 W/cm2 thin foils can be irradiated in the target-normal sheath acceleration regime driving ion acceleration in the forward direction above 1 MeV per charge state. The distributions of emitted ions in terms of energy, charge state and angular emission are controlled by laser parameters, irradiation conditions, target geometry and composition. Advanced targets can be employed to increase the laser absorption in thin foils and to enhance the energy and the yield of the ion acceleration process. Semiconductor detectors, Thomson parabola spectrometer and streak camera can be employed as online plasma diagnostics to monitor the plasma parameters, shot by shot. Some applications in the field of the multiple ion implantation, hadrontherapy and nuclear physics are reported.

  1. Antenna development for high field plasma imaging.

    Science.gov (United States)

    Kong, X; Domier, C W; Luhmann, N C

    2010-10-01

    Electron cyclotron emission imaging (ECEI) and microwave imaging reflectometry (MIR) are two microwave nonperturbing plasma visualization techniques that employ millimeter-wave imaging arrays with lens-coupled planar antennas, yielding time-resolved images of temperature (via ECEI) and electron density (via MIR) fluctuations within high temperature magnetic fusion plasmas. A series of new planar antennas have been developed that extend this technology to frequencies as high as 220 GHz for use on high field plasma devices with toroidal fields in excess of 3 T. Antenna designs are presented together with theoretical calculations, simulations, and experimental measurements.

  2. Role of spectroscopic diagnostics in studying nanosecond laser-plasma interaction

    Science.gov (United States)

    Burger, Miloš; Pantić, Dragan; Nikolić, Zoran; Djeniže, Stevan

    2017-05-01

    We studied the impact of varying the intensity of Nd:YAG nanosecond 1.06 μm laser radiation on the morphology and internal structure of copper plasma plumes were examined. Standard diagnostic techniques used to deduce axial distributions of electron density and temperature revealed effects of a pronounced plasma screening regime. Methods of fast imaging spectroscopy are used to examine the transition from weak- to high-screening plasma, applying irradiance on the order of 109 W cm-2 in helium atmosphere. Behavior of both ionized and neutral species was observed up to 1 μs after the laser pulse. Showing significant differences with an increase of laser irradiance, the change in plasma propagation mechanisms is attributed to internal shockwave dynamics within the plasma plume. Implications of observed behavior to plasma uniformity can affect diagnostics, and are relevant to both modeling and applications. Contribution to the Topical Issue "Physics of Ionized Gases (SPIG 2016)", edited by Goran Poparic, Bratislav Obradovic, Dragana Maric and Aleksandar Milosavljevic.

  3. High density plasmas and new diagnostics: An overview (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Celona, L., E-mail: celona@lns.infn.it; Gammino, S.; Mascali, D. [Istituto Nazionale di Fisica Nucleare—Laboratori Nazionali del Sud, Via S. Sofia 62, 95123 Catania (Italy)

    2016-02-15

    One of the limiting factors for the full understanding of Electron Cyclotron Resonance Ion Sources (ECRISs) fundamental mechanisms consists of few types of diagnostic tools so far available for such compact machines. Microwave-to-plasma coupling optimisation, new methods of density overboost provided by plasma wave generation, and magnetostatic field tailoring for generating a proper electron energy distribution function, suitable for optimal ion beams formation, require diagnostic tools spanning across the entire electromagnetic spectrum from microwave interferometry to X-ray spectroscopy; these methods are going to be implemented including high resolution and spatially resolved X-ray spectroscopy made by quasi-optical methods (pin-hole cameras). The ion confinement optimisation also requires a complete control of cold electrons displacement, which can be performed by optical emission spectroscopy. Several diagnostic tools have been recently developed at INFN-LNS, including “volume-integrated” X-ray spectroscopy in low energy domain (2-30 keV, by using silicon drift detectors) or high energy regime (>30 keV, by using high purity germanium detectors). For the direct detection of the spatially resolved spectral distribution of X-rays produced by the electronic motion, a “pin-hole camera” has been developed also taking profit from previous experiences in the ECRIS field. The paper will give an overview of INFN-LNS strategy in terms of new microwave-to-plasma coupling schemes and advanced diagnostics supporting the design of new ion sources and for optimizing the performances of the existing ones, with the goal of a microwave-absorption oriented design of future machines.

  4. High density plasmas and new diagnostics: An overview (invited).

    Science.gov (United States)

    Celona, L; Gammino, S; Mascali, D

    2016-02-01

    One of the limiting factors for the full understanding of Electron Cyclotron Resonance Ion Sources (ECRISs) fundamental mechanisms consists of few types of diagnostic tools so far available for such compact machines. Microwave-to-plasma coupling optimisation, new methods of density overboost provided by plasma wave generation, and magnetostatic field tailoring for generating a proper electron energy distribution function, suitable for optimal ion beams formation, require diagnostic tools spanning across the entire electromagnetic spectrum from microwave interferometry to X-ray spectroscopy; these methods are going to be implemented including high resolution and spatially resolved X-ray spectroscopy made by quasi-optical methods (pin-hole cameras). The ion confinement optimisation also requires a complete control of cold electrons displacement, which can be performed by optical emission spectroscopy. Several diagnostic tools have been recently developed at INFN-LNS, including "volume-integrated" X-ray spectroscopy in low energy domain (2-30 keV, by using silicon drift detectors) or high energy regime (>30 keV, by using high purity germanium detectors). For the direct detection of the spatially resolved spectral distribution of X-rays produced by the electronic motion, a "pin-hole camera" has been developed also taking profit from previous experiences in the ECRIS field. The paper will give an overview of INFN-LNS strategy in terms of new microwave-to-plasma coupling schemes and advanced diagnostics supporting the design of new ion sources and for optimizing the performances of the existing ones, with the goal of a microwave-absorption oriented design of future machines.

  5. Diagnostic imaging in patients with retinitis pigmentosa.

    Science.gov (United States)

    Mitamura, Yoshinori; Mitamura-Aizawa, Sayaka; Nagasawa, Toshihiko; Katome, Takashi; Eguchi, Hiroshi; Naito, Takeshi

    2012-01-01

    Retinitis pigmentosa (RP) is a progressive inherited retinal disease, and patients with RP have reduced visual function caused by a degeneration of the photoreceptors and retinal pigment epithelium (RPE). At the end stage of RP, the degeneration of the photoreceptors in the fovea reduces central vision, and RP is one of the main causes of acquired blindness in developed countries. Therefore, morphological and functional assessments of the photoreceptors in the macula area can be useful in estimating the residual retinal function in RP patients. Optical coherence tomography (OCT) is a well-established method of examining the retinal architecture in situ. The photoreceptor inner/outer segment (IS/OS) junction is observed as a distinct, highly reflective line by OCT. The presence of the IS/OS junction in the OCT images is essential for normal visual function. Fundus autofluorescence (FAF) results from the accumulation of lipofuscin in the RPE cells and has been used to investigate RPE and retinal function. More than one-half of RP patients have an abnormally high density parafoveal FAF ring (AF ring). The AF ring represents the border between functional and dysfunctional retina. In this review, we shall summarize recent progress on diagnostic imaging in eyes with RP.

  6. Diagnostic for Plasma Enhanced Chemical Vapor Deposition and Etch Systems

    Science.gov (United States)

    Cappelli, Mark A.

    1999-01-01

    concentration, temperature, ion energy distribution, and electron number density. A wide variety of diagnostic techniques are under development through this consortium grant to measure these parameters. including molecular beam mass spectrometry (MBMS). Fourier transform infrared (FTIR) spectroscopy, broadband ultraviolet (UV) absorption spectroscopy, a compensated Langmuir probe. Additional diagnostics. Such as microwave interferometry and microwave absorption for measurements of plasma density and radical concentrations are also planned.

  7. Rex shunt preoperative imaging: diagnostic capability of imaging modalities.

    Directory of Open Access Journals (Sweden)

    Sharon W Kwan

    Full Text Available The purpose of this study was to evaluate the diagnostic capability of imaging modalities used for preoperative mesenteric-left portal bypass ("Rex shunt" planning. Twenty patients with extrahepatic portal vein thrombosis underwent 57 preoperative planning abdominal imaging studies. Two readers retrospectively reviewed these studies for an ability to confidently determine left portal vein (PV patency, superior mesenteric vein (SMV patency, and intrahepatic left and right PV contiguity. In this study, computed tomographic arterial portography allowed for confident characterization of left PV patency, SMV patency and left and right PV continuity in 100% of the examinations. Single phase contrast-enhanced CT, multi-phase contrast-enhanced CT, multiphase contrast-enhanced MRI, and transarterial portography answered all key diagnostic questions in 33%, 30%, 0% and 8% of the examinations, respectively. In conclusion, of the variety of imaging modalities that have been employed for Rex shunt preoperative planning, computed tomographic arterial portography most reliably allows for assessment of left PV patency, SMV patency, and left and right PV contiguity in a single study.

  8. PROMINENCE PLASMA DIAGNOSTICS THROUGH EXTREME-ULTRAVIOLET ABSORPTION

    Energy Technology Data Exchange (ETDEWEB)

    Landi, E. [Department of Atmospheric, Oceanic and Space Sciences, University of Michigan, Ann Arbor, MI 48109 (United States); Reale, F. [Dipartimento di Fisica e Chimica, Universita di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy)

    2013-07-20

    In this paper, we introduce a new diagnostic technique that uses EUV and UV absorption to determine the electron temperature and column emission measure, as well as the He/H relative abundance of the absorbing plasma. If a realistic assumption on the geometry of the latter can be made and a spectral code such as CHIANTI is used, then this technique can also yield the absorbing plasma hydrogen and electron density. This technique capitalizes on the absorption properties of hydrogen and helium at different wavelength ranges and temperature regimes. Several cases where this technique can be successfully applied are described. This technique works best when the absorbing plasma is hotter than 15,000 K. We demonstrate this technique on AIA observations of plasma absorption during a coronal mass ejection eruption. This technique can be easily applied to existing observations of prominences and cold plasmas in the Sun from almost all space missions devoted to the study of the solar atmosphere, which we list.

  9. Diagnostic suite of the C-2U advanced beam-driven field-reversed configuration plasma experiment

    Science.gov (United States)

    Thompson, M. C.; Gota, H.; Putvinski, S.; Tuszewski, M.; Binderbauer, M.

    2016-11-01

    The C-2U experiment at Tri Alpha Energy studies the evolution of field-reversed configuration (FRC) plasmas sustained by neutral beam injection. Data on the FRC plasma performance are provided by a comprehensive suite of diagnostics that includes magnetic sensors, interferometry, Thomson scattering, spectroscopy, bolometry, reflectometry, neutral particle analyzers, and fusion product detectors. While many of these diagnostic systems were inherited from the preceding experiment C-2, C-2U has a variety of new and upgraded diagnostic systems: multi-chord far-infrared polarimetry, multiple fast imaging cameras with selectable atomic line filters, proton detector arrays, and 100 channel bolometer units capable of observing multiple regions of the spectrum simultaneously. In addition, extensive ongoing work focuses on advanced methods of measuring separatrix shape and plasma current profile that will facilitate equilibrium reconstruction and active control of the FRC plasma.

  10. Diagnostic suite of the C-2U advanced beam-driven field-reversed configuration plasma experiment

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, M. C., E-mail: mthompson@trialphaenergy.com; Gota, H.; Putvinski, S.; Tuszewski, M.; Binderbauer, M. [Tri Alpha Energy, Inc., Rancho Santa Margarita, California 92688 (United States)

    2016-11-15

    The C-2U experiment at Tri Alpha Energy studies the evolution of field-reversed configuration (FRC) plasmas sustained by neutral beam injection. Data on the FRC plasma performance are provided by a comprehensive suite of diagnostics that includes magnetic sensors, interferometry, Thomson scattering, spectroscopy, bolometry, reflectometry, neutral particle analyzers, and fusion product detectors. While many of these diagnostic systems were inherited from the preceding experiment C-2, C-2U has a variety of new and upgraded diagnostic systems: multi-chord far-infrared polarimetry, multiple fast imaging cameras with selectable atomic line filters, proton detector arrays, and 100 channel bolometer units capable of observing multiple regions of the spectrum simultaneously. In addition, extensive ongoing work focuses on advanced methods of measuring separatrix shape and plasma current profile that will facilitate equilibrium reconstruction and active control of the FRC plasma.

  11. Imaging diagnostics of the foot; Bildgebende Diagnostik des Fusses

    Energy Technology Data Exchange (ETDEWEB)

    Szeimies, Ulrike; Staebler, Axel [Radiologie in Muenchen-Harlaching, Muenchen (Germany); Walther, Markus (eds.) [Schoen-Klinik Muenchen-Harlaching, Muenchen (Germany). Zentrum fuer Fuss- und Sprunggelenkchirurgie

    2012-11-01

    The book on imaging diagnostics of the foot contains the following chapters: (1) Imaging techniques. (2) Clinical diagnostics. (3) Ankle joint and hind foot. (4) Metatarsus. (5) Forefoot. (6) Pathology of plantar soft tissue. (7) Nervous system diseases. (8) Diseases without specific anatomic localization. (9) System diseases including the foot. (10) Tumor like lesions. (11) Normative variants.

  12. Optimized and Automated design of Plasma Diagnostics for Additive Manufacture

    Science.gov (United States)

    Stuber, James; Quinley, Morgan; Melnik, Paul; Sieck, Paul; Smith, Trevor; Chun, Katherine; Woodruff, Simon

    2016-10-01

    Despite having mature designs, diagnostics are usually custom designed for each experiment. Most of the design can be now be automated to reduce costs (engineering labor, and capital cost). We present results from scripted physics modeling and parametric engineering design for common optical and mechanical components found in many plasma diagnostics and outline the process for automated design optimization that employs scripts to communicate data from online forms through proprietary and open-source CAD and FE codes to provide a design that can be sent directly to a printer. As a demonstration of design automation, an optical beam dump, baffle and optical components are designed via an automated process and printed. Supported by DOE SBIR Grant DE-SC0011858.

  13. Solar Prominence Modelling and Plasma Diagnostics at ALMA Wavelengths

    Science.gov (United States)

    Rodger, Andrew; Labrosse, Nicolas

    2017-09-01

    Our aim is to test potential solar prominence plasma diagnostics as obtained with the new solar capability of the Atacama Large Millimeter/submillimeter Array (ALMA). We investigate the thermal and plasma diagnostic potential of ALMA for solar prominences through the computation of brightness temperatures at ALMA wavelengths. The brightness temperature, for a chosen line of sight, is calculated using the densities of electrons, hydrogen, and helium obtained from a radiative transfer code under non-local thermodynamic equilibrium (non-LTE) conditions, as well as the input internal parameters of the prominence model in consideration. Two distinct sets of prominence models were used: isothermal-isobaric fine-structure threads, and large-scale structures with radially increasing temperature distributions representing the prominence-to-corona transition region. We compute brightness temperatures over the range of wavelengths in which ALMA is capable of observing (0.32 - 9.6 mm), however, we particularly focus on the bands available to solar observers in ALMA cycles 4 and 5, namely 2.6 - 3.6 mm (Band 3) and 1.1 - 1.4 mm (Band 6). We show how the computed brightness temperatures and optical thicknesses in our models vary with the plasma parameters (temperature and pressure) and the wavelength of observation. We then study how ALMA observables such as the ratio of brightness temperatures at two frequencies can be used to estimate the optical thickness and the emission measure for isothermal and non-isothermal prominences. From this study we conclude that for both sets of models, ALMA presents a strong thermal diagnostic capability, provided that the interpretation of observations is supported by the use of non-LTE simulation results.

  14. An accurate automated technique for quasi-optics measurement of the microwave diagnostics for fusion plasma

    Science.gov (United States)

    Hu, Jianqiang; Liu, Ahdi; Zhou, Chu; Zhang, Xiaohui; Wang, Mingyuan; Zhang, Jin; Feng, Xi; Li, Hong; Xie, Jinlin; Liu, Wandong; Yu, Changxuan

    2017-08-01

    A new integrated technique for fast and accurate measurement of the quasi-optics, especially for the microwave/millimeter wave diagnostic systems of fusion plasma, has been developed. Using the LabVIEW-based comprehensive scanning system, we can realize not only automatic but also fast and accurate measurement, which will help to eliminate the effects of temperature drift and standing wave/multi-reflection. With the Matlab-based asymmetric two-dimensional Gaussian fitting method, all the desired parameters of the microwave beam can be obtained. This technique can be used in the design and testing of microwave diagnostic systems such as reflectometers and the electron cyclotron emission imaging diagnostic systems of the Experimental Advanced Superconducting Tokamak.

  15. Polarizer design for millimeter-wave plasma diagnostics.

    Science.gov (United States)

    Leipold, F; Salewski, M; Jacobsen, A S; Jessen, M; Korsholm, S B; Michelsen, P K; Nielsen, S K; Stejner, M

    2013-08-01

    Radiation from magnetized plasmas is in general elliptically polarized. In order to convert the elliptical polarization to linear polarization, mirrors with grooved surfaces are currently employed in our collective Thomson scattering diagnostic at ASDEX Upgrade. If these mirrors can be substituted by birefringent windows, the microwave receivers can be designed to be more compact at lower cost. Sapphire windows (a-cut) as well as grooved high density polyethylene windows can serve this purpose. The sapphire window can be designed such that the calculated transmission of the wave energy is better than 99%, and that of the high density polyethylene can be better than 97%.

  16. Broadband notch filter design for millimeter-wave plasma diagnostics

    DEFF Research Database (Denmark)

    Furtula, Vedran; Michelsen, Poul; Leipold, Frank;

    2010-01-01

    Notch filters are integrated in plasma diagnostic systems to protect millimeter-wave receivers from intensive stray radiation. Here we present a design of a notch filter with a center frequency of 140 GHz, a rejection bandwidth of ∼ 900 MHz, and a typical insertion loss below 2 dB in the passband...... of ±9 GHz. The design is based on a fundamental rectangular waveguide with eight cylindrical cavities coupled by T-junction apertures formed as thin slits. Parameters that affect the notch performance such as physical lengths and conductor materials are discussed. The excited resonance mode...

  17. Cross-diagnostic comparison of fluctuation measurements in a cylindrical argon plasma

    Science.gov (United States)

    Light, Adam; Chakraborty Thakur, Saikat; Tynan, George

    2016-10-01

    The advent of fast imaging diagnostics, which provide two-dimensional measurements on relevant plasma time scales, has proven invaluable for interpreting plasma dynamics in laboratory devices. Despite its success, imaging remains a qualitative aid for many studies, because intensity is difficult to map onto a single physical variable for use in a theoretical model. This work continues our exploration of the relationship between visible-light imaging and other diagnostics in the Controlled Shear Decorrelation Experiment (CSDX). CSDX is a well-characterized linear machine producing dense plasmas relevant to the tokamak edge (Te 5 eV, ne 1013 /cc). Visible light from ArI and ArII line emission is collected at high frame rates using a fast digital camera, floating potential and ion-saturation current are measured by an array of electrostatic probe tips, and average profiles of ion temperature and velocity are obtained using laser-induced fluorescence (LIF). We present a detailed comparison between these measurements, including temporal, spatial, and spectral properties in various operational regimes.

  18. Automatization of hardware configuration for plasma diagnostic system

    Science.gov (United States)

    Wojenski, A.; Pozniak, K. T.; Kasprowicz, G.; Kolasinski, P.; Krawczyk, R. D.; Zabolotny, W.; Linczuk, P.; Chernyshova, M.; Czarski, T.; Malinowski, K.

    2016-09-01

    Soft X-ray plasma measurement systems are mostly multi-channel, high performance systems. In case of the modular construction it is necessary to perform sophisticated system discovery in parallel with automatic system configuration. In the paper the structure of the modular system designed for tokamak plasma soft X-ray measurements is described. The concept of the system discovery and further automatic configuration is also presented. FCS application (FMC/ FPGA Configuration Software) is used for running sophisticated system setup with automatic verification of proper configuration. In order to provide flexibility of further system configurations (e.g. user setup), common communication interface is also described. The approach presented here is related to the automatic system firmware building presented in previous papers. Modular construction and multichannel measurements are key requirement in term of SXR diagnostics with use of GEM detectors.

  19. Challenges in plasma and laser wakefield accelerated beams diagnostic

    Energy Technology Data Exchange (ETDEWEB)

    Cianchi, A., E-mail: alessandro.cianchi@roma2.infn.it [University of Rome Tor Vergata and INFN, V. della Ricerca Scientifica 1, 00133 Rome (Italy); Anania, M.P.; Bellaveglia, M.; Castellano, M.; Chiadroni, E.; Ferrario, M.; Gatti, G. [INFN-LNF - Via E. Fermi 40, 00044 Frascati (RM) (Italy); Marchetti, B. [DESY, Platanenallee 6, D-15738 Zeuthen (Germany); Mostacci, A. [University of Rome La Sapienza, P.le Aldo Moro 5, 00185 Rome (Italy); Pompili, R. [INFN-LNF - Via E. Fermi 40, 00044 Frascati (RM) (Italy); Ronsivalle, C. [ENEA C.R. Frascati, Via E. Fermi,45 00044 Frascati (RM) (Italy); Rossi, A.R.; Serafini, L. [INFN-Mi, Via Celoria, 16 20133 Milano (Italy)

    2013-08-21

    The new frontier in the particle beam accelerator is the so called plasma acceleration. Using the strong electric field inside a plasma it is possible to achieve accelerating gradients in the order of magnitude larger with respect to the actual technologies. Different schemes have been proposed and several already tested, producing beams of energy of several GeV. Mainly two approaches are followed: either the beam is directly produced by the interaction of a TW/PW class laser with a gas jet or a preexisting particle beam is accelerated in a plasma channel. In both cases a precise determination of the emerging beam parameters is mandatory for the fine tuning of the devices. The measurement of these parameters, in particular the emittance, is not trivial, mainly due to the large energy spread and to the tight focusing of these beams or to the background noise produced in the plasma channel. We show the problems related to the diagnostic of this kind of beams and the proposed or already realized solutions.

  20. Challenges in plasma and laser wakefield accelerated beams diagnostic

    Science.gov (United States)

    Cianchi, A.; Anania, M. P.; Bellaveglia, M.; Castellano, M.; Chiadroni, E.; Ferrario, M.; Gatti, G.; Marchetti, B.; Mostacci, A.; Pompili, R.; Ronsivalle, C.; Rossi, A. R.; Serafini, L.

    2013-08-01

    The new frontier in the particle beam accelerator is the so called plasma acceleration. Using the strong electric field inside a plasma it is possible to achieve accelerating gradients in the order of magnitude larger with respect to the actual technologies. Different schemes have been proposed and several already tested, producing beams of energy of several GeV. Mainly two approaches are followed: either the beam is directly produced by the interaction of a TW/PW class laser with a gas jet or a preexisting particle beam is accelerated in a plasma channel. In both cases a precise determination of the emerging beam parameters is mandatory for the fine tuning of the devices. The measurement of these parameters, in particular the emittance, is not trivial, mainly due to the large energy spread and to the tight focusing of these beams or to the background noise produced in the plasma channel. We show the problems related to the diagnostic of this kind of beams and the proposed or already realized solutions.

  1. Optical diagnostics for laser wakefields in plasma channels

    Science.gov (United States)

    Gaul, E. W.; Le Blanc, S. P.; Downer, M. C.

    1998-11-01

    Laser wakefield accelerators can excite large amplitude electrostatic fields (E >= 100 GV/m) which are potentially suitable for compact accelerators and advanced high energy colliders. An accurate diagnostic tool is necessary to test the physical effects in the wakefield predicted by theory and numerical simulations, and to have control over experiments. Frequency domain interferometry (FDI) (C. W. Siders et. al.), Phys. Rev. Lett. 76, 3570 (1995) has been developed in previous work. We experimentally demonstrate single-shot FDI as a sensitive diagnostic technique for probing laser wakefields. To generate wakefields longer than the diffraction limit, optical guiding of the laser pulse is necessary. An optical guide is formed by the hydrodynamic expansion of a cylindrical shock wave driven by a laser heated plasma, which is generated by laser pulse focused with an axicon lens (C. G. Durfee and H. M. Milchberg, Phys. Rev. Lett. 71, 2409 (1993)) to intensities of ~= 10^13 W/cm^2. These are too low to reach multi-photon ionization or significant collisional ionization in <= 1 atm helium. We preionize Helium gas with an electrical discharge for efficient inverse bremsstrahlung absorption of the laser pulse and formation of a plasma channel. Spatially resolved chirped pulse interferometry is used to measure the radial electron density profile of the channel.

  2. Electromagnetic Analysis of ITER Diagnostic Equatorial Port Plugs During Plasma Disruptions

    Energy Technology Data Exchange (ETDEWEB)

    Y. Zhai, R. Feder, A. Brooks, M. Ulrickson, C.S. Pitcher and G.D. Loesser

    2012-08-27

    ITER diagnostic port plugs perform many functionsincluding structural support of diagnostic systems under high electromagnetic loads while allowing for diagnostic access to the plasma. The design of diagnostic equatorial port plugs (EPP) are largely driven by electromagnetic loads and associate responses of EPP structure during plasma disruptions and VDEs. This paper summarizes results of transient electromagnetic analysis using Opera 3d in support of the design activities for ITER diagnostic EPP. A complete distribution of disruption loads on the Diagnostic First Walls (DFWs), Diagnostic Shield Modules (DSMs) and the EPP structure, as well as impact on the system design integration due to electrical contact among various EPP structural components are discussed.

  3. Modifications to the synthetic aperture microwave imaging diagnostic

    Science.gov (United States)

    Brunner, K. J.; Chorley, J. C.; Dipper, N. A.; Naylor, G.; Sharples, R. M.; Taylor, G.; Thomas, D. A.; Vann, R. G. L.

    2016-11-01

    The synthetic aperture microwave imaging diagnostic has been operating on the MAST experiment since 2011. It has provided the first 2D images of B-X-O mode conversion windows and showed the feasibility of conducting 2D Doppler back-scattering experiments. The diagnostic heavily relies on field programmable gate arrays to conduct its work. Recent successes and newly gained experience with the diagnostic have led us to modify it. The enhancements will enable pitch angle profile measurements, O and X mode separation, and the continuous acquisition of 2D DBS data. The diagnostic has also been installed on the NSTX-U and is acquiring data since May 2016.

  4. Papers presented at the Tenth Topical Conference on High-Temperature Plasma Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    This report contains papers on the following topics: Effects of limited spatial resolution on fluctuation measurements; vertical viewing of electron-cyclotron radiation in Text-U; measurement of temperature fluctuations from electron-cyclotron emission; a varying cross section magnetic coil diagnostic used in digital feedback control of plasma position in Text-Upgrade; high-sensitivity, high resolution measurements of radiated power on Text-U; wave launching as a diagnostic tool to investigate plasma turbulence; edge parameters from an energy analyzer and particle transport on Text-U; initial results from a charge exchange q-Diagnostic on Text-U; a method for neutral spectra analysis taking ripple-trapped particle losses into account; application of a three sample volume{sup S(k,{omega}}) estimate to optical measurements of turbulence on Text; initial operation of the 2D Firsis on Text-Upgrade; horizontal-view interferometer on Text-Upgrade; plasma potential measurements on Text-Upgrade with A 2 MeV heavy ion beam; fluctuation measurements using the 2 MeV heavy ion beam probe on Text-U; the time domain triple probe method; a phase contrast imaging system for Text-U; and development of rugged corner cube detectors for the Text-U-Fir interferometer. These papers have been placed on the database elsewhere.

  5. Establishing isokinetic flow for a plasma torch exhaust gas diagnostic for a plasma hearth furnace

    Energy Technology Data Exchange (ETDEWEB)

    Pollack, B.R.

    1996-05-01

    Real time monitoring of toxic metallic effluents in confined gas streams can be accomplished through use of Microwave Induced Plasmas to perform atomic emission spectroscopy, For this diagnostic to be viable it is necessary that it sample from the flowstream of interest in an isokinetic manner. A method of isokinetic sampling was established for this device for use in the exhaust system of a plasma hearth vitrification furnace. The flow and entrained particulate environment were simulated in the laboratory setting using a variable flow duct of the same dimensions (8-inch diameter, schedule 40) as that in the field and was loaded with similar particulate (less than 10 {mu}m in diameter) of lake bed soil typically used in the vitrification process. The flow from the furnace was assumed to be straight flow. To reproduce this effect a flow straightener was installed in the device. An isokinetic sampling train was designed to include the plasma torch, with microwave power input operating at 2.45 GHz, to match local freestream velocities between 800 and 2400 ft/sec. The isokinetic sampling system worked as planned and the plasma torch had no difficulty operating at the required flowrates. Simulation of the particulate suspension was also successful. Steady particle feeds were maintained over long periods of time and the plasma diagnostic responded as expected.

  6. Establishing isokinetic flow for a plasma torch exhaust gas diagnostic for a plasma hearth furnace

    Energy Technology Data Exchange (ETDEWEB)

    Pollack, Brian R. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    1996-05-01

    Real time monitoring of toxic metallic effluents in confined gas streams can be accomplished through use of Microwave Induced Plasmas to perform atomic emission spectroscopy, For this diagnostic to be viable it is necessary that it sample from the flowstream of interest in an isokinetic manner. A method of isokinetic sampling was established for this device for use in the exhaust system of a plasma hearth vitrification furnace. The flow and entrained particulate environment were simulated in the laboratory setting using a variable flow duct of the same dimensions (8-inch diameter, schedule 40) as that in the field and was loaded with similar particulate (less than 10 μm in diameter) of lake bed soil typically used in the vitrification process. The flow from the furnace was assumed to be straight flow. To reproduce this effect a flow straightener was installed in the device. An isokinetic sampling train was designed to include the plasma torch, with microwave power input operating at 2.45 GHz, to match local freestream velocities between 800 and 2400 ft/sec. The isokinetic sampling system worked as planned and the plasma torch had no difficulty operating at the required flowrates. Simulation of the particulate suspension was also successful. Steady particle feeds were maintained over long periods of time and the plasma diagnostic responded as expected.

  7. Cost-effectiveness modelling in diagnostic imaging: a stepwise approach

    NARCIS (Netherlands)

    Sailer, A.M.; Zwam, W.H. van; Wildberger, J.E.; Grutters, J.P.C.

    2015-01-01

    Diagnostic imaging (DI) is the fastest growing sector in medical expenditures and takes a central role in medical decision-making. The increasing number of various and new imaging technologies induces a growing demand for cost-effectiveness analysis (CEA) in imaging technology assessment. In this ar

  8. Development of Diagnostics for Large-Scale Experiments with Dense Magnetized Plasmas - MJ Plasma-focus diagnostics systems

    Energy Technology Data Exchange (ETDEWEB)

    Scholz, M.; Karpinski, L.; Paduch, M.; Pisarczyk, T.; Zielinska, E.; Chodukowski, T. [Institute of Plasma Physics and Laser Microfusion IPPLM, 01-497 Warsaw (Poland); Sadowski, M.J. [Institute of Plasma Physics and Laser Microfusion IPPLM, 01-497 Warsaw (Poland)] [The Andrzej Soltan Institute for Nuclear Studies IPJ, 05-400 Otwock-Swiert (Poland); Skladnik-Sadowska, E.; Czaus, K.; Kwiatkowski, R.; Malinowski, K. [The Andrzej Soltan Institute for Nuclear Studies IPJ, 05-400 Otwock-Swiert (Poland); Krauz, S. [RNC Kurchatov Institute, Moscow (Russian Federation); Mitrovanov, K. [FGUP GNC RF Triniti, Troick (Russian Federation)

    2011-07-01

    This document presents the diagnostics arrangements and interesting results of research on fusion pulsed plasma, which was generated within the large PF-1000 facility operated in the Institute of Plasma Physics and Laser Microfusion (Warsaw, Poland). Experimental studies were carried out with the following diagnostic techniques: 1) Rogovski coil for current measurements; 2) Four dI/dt probes in different places around the collector of PF-1000; 3) Voltage divider; 4) Mach-Zender interferometer (16 frames); 5) Fast scintillation probes for X-ray and neutron detection; 6) Silver activation counters; 7) Specially prepared current probes; 8) Thomson spectrometer for mass- and energy-analysis of deuterium beams; 9) Ion-pinhole cameras equipped with nuclear-track detectors, etc. The studies have been carried out with the pure deuterium filling, and particular attention was paid to correlations between the fast-neutron emission and an evolution of plasma parameters. The total fusion-neutron yield, as measured with four silver-activation counters, was found to be up to 7*10{sup 11} per shot, depending on the experimental conditions. Correlations of the neutron pulses with interferometric frame-pictures of the PF pinch column were studied. From time-of-flight (ToF) measurements of the fusion neutrons it was possible to estimate a CM velocity of deuterons involved in the D-D reactions. The fast fusion-produced protons have also been recorded and analyzed by means pinhole cameras and shielded track detectors. The document is composed of an abstract followed by the slides of the presentation. (authors)

  9. Optimisation of patient protection and image quality in diagnostic ...

    African Journals Online (AJOL)

    Optimisation of patient protection and image quality in diagnostic radiology. ... The study leads to the introduction of the concept of plan- do-check-act on QC results ... (QA) programme and continues to collect data for establishment of DRL's.

  10. Electromagnetic Analysis For The Design Of ITER Diagnostic Port Plugs During Plasma Disruptions

    Energy Technology Data Exchange (ETDEWEB)

    Zhai, Y

    2014-03-03

    ITER diagnostic port plugs perform many functions including structural support of diagnostic systems under high electromagnetic loads while allowing for diagnostic access to plasma. The design of diagnotic equatorial port plugs (EPP) are largely driven by electromagnetic loads and associate response of EPP structure during plasma disruptions and VDEs. This paper summarizes results of transient electromagnetic analysis using Opera 3d in support of the design activities for ITER diagnostic EPP. A complete distribution of disruption loads on the Diagnostic First Walls (DFWs). Diagnostic Shield Modules (DSMs) and the EPP structure, as well as impact on the system design integration due to electrical contact among various EPP structural components are discussed.

  11. Electron beam charge diagnostics for laser plasma accelerators

    Directory of Open Access Journals (Sweden)

    K. Nakamura

    2011-06-01

    Full Text Available A comprehensive study of charge diagnostics is conducted to verify their validity for measuring electron beams produced by laser plasma accelerators (LPAs. First, a scintillating screen (Lanex was extensively studied using subnanosecond electron beams from the Advanced Light Source booster synchrotron, at the Lawrence Berkeley National Laboratory. The Lanex was cross calibrated with an integrating current transformer (ICT for up to the electron energy of 1.5 GeV, and the linear response of the screen was confirmed for charge density and intensity up to 160  pC/mm^{2} and 0.4  pC/(ps  mm^{2}, respectively. After the radio-frequency accelerator based cross calibration, a series of measurements was conducted using electron beams from an LPA. Cross calibrations were carried out using an activation-based measurement that is immune to electromagnetic pulse noise, ICT, and Lanex. The diagnostics agreed within ±8%, showing that they all can provide accurate charge measurements for LPAs.

  12. Electron Beam Charge Diagnostics for Laser Plasma Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Kei; Gonsalves, Anthony; Lin, Chen; Smith, Alan; Rodgers, David; Donahue, Rich; Byrne, Warren; Leemans, Wim

    2011-06-27

    A comprehensive study of charge diagnostics is conducted to verify their validity for measuring electron beams produced by laser plasma accelerators (LPAs). First, a scintillating screen (Lanex) was extensively studied using subnanosecond electron beams from the Advanced Light Source booster synchrotron, at the Lawrence Berkeley National Laboratory. The Lanex was cross calibrated with an integrating current transformer (ICT) for up to the electron energy of 1.5 GeV, and the linear response of the screen was confirmed for charge density and intensity up to 160 pC/mm{sup 2} and 0.4 pC/(ps mm{sup 2}), respectively. After the radio-frequency accelerator based cross calibration, a series of measurements was conducted using electron beams from an LPA. Cross calibrations were carried out using an activation-based measurement that is immune to electromagnetic pulse noise, ICT, and Lanex. The diagnostics agreed within {+-}8%, showing that they all can provide accurate charge measurements for LPAs.

  13. An Optical Streak Diagnostic for Observing Anode-Cathode Plasmas for Radiographic Source Development

    Energy Technology Data Exchange (ETDEWEB)

    Droemer, Darryl W. [National Security Technologies, LLC; Crain, Marlon D.; Lare, Gregory A. [National Security Technologies, LLC; Bennett, Nichelle L. [National Security Technologies, LLC; Johnston, Mark D. [Sandia National Laboratories

    2013-06-13

    National Security Technologies, LLC, and Sandia National Laboratories are collaborating in the development of pulsed power–driven flash x-ray radiographic sources that utilize high-intensity electron beam diodes. The RITS 6 (Radiographic Integrated Test Stand) accelerator at Sandia is used to drive a self magnetic pinch diode to produce a Bremsstrahlung x-ray source. The high electric fields and current densities associated with these short A-K gap pinch beam diodes present many challenges in diode development. Plasmas generated at both the anode and cathode affect the diode performance, which is manifested in varying spot (source) sizes, total dose output, and impedance profiles. Understanding the nature of these plasmas including closure rates and densities is important in modeling their behavior and providing insight into their mitigation. In this paper we describe a streak camera–based optical diagnostic that is capable of observing and measuring plasma evolution within the A-K gap. By imaging a region of interest onto the input slit of a streak camera, we are able to produce a time-resolved one-dimensional image of the evolving plasma. Typical data are presented.

  14. X-ray pinhole camera setups used in the Atomki ECR Laboratory for plasma diagnostics

    Science.gov (United States)

    Rácz, R.; Biri, S.; Pálinkás, J.; Mascali, D.; Castro, G.; Caliri, C.; Romano, F. P.; Gammino, S.

    2016-02-01

    Imaging of the electron cyclotron resonance (ECR) plasmas by using CCD camera in combination with a pinhole is a non-destructive diagnostics method to record the strongly inhomogeneous spatial density distribution of the X-ray emitted by the plasma and by the chamber walls. This method can provide information on the location of the collisions between warm electrons and multiple charged ions/atoms, opening the possibility to investigate the direct effect of the ion source tuning parameters to the plasma structure. The first successful experiment with a pinhole X-ray camera was carried out in the Atomki ECR Laboratory more than 10 years ago. The goal of that experiment was to make the first ECR X-ray photos and to carry out simple studies on the effect of some setting parameters (magnetic field, extraction, disc voltage, gas mixing, etc.). Recently, intensive efforts were taken to investigate now the effect of different RF resonant modes to the plasma structure. Comparing to the 2002 experiment, this campaign used wider instrumental stock: CCD camera with a lead pinhole was placed at the injection side allowing X-ray imaging and beam extraction simultaneously. Additionally, Silicon Drift Detector (SDD) and High Purity Germanium (HPGe) detectors were installed to characterize the volumetric X-ray emission rate caused by the warm and hot electron domains. In this paper, detailed comparison study on the two X-ray camera and detector setups and also on the technical and scientific goals of the experiments is presented.

  15. X-ray pinhole camera setups used in the Atomki ECR Laboratory for plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Rácz, R., E-mail: rracz@atomki.hu; Biri, S.; Pálinkás, J. [Institute for Nuclear Research (Atomki), Hungarian Academy of Sciences, Bem tér 18/C, H-4026 Debrecen (Hungary); Mascali, D.; Castro, G.; Caliri, C.; Gammino, S. [Instituto Nazionale di Fisica Nucleare—Laboratori Nazionali del Sud, via S. Sofia 62, 95123 Catania (Italy); Romano, F. P. [Instituto Nazionale di Fisica Nucleare—Laboratori Nazionali del Sud, via S. Sofia 62, 95123 Catania (Italy); CNR, Istituto per i Beni Archeologici e Monumentali, Via Biblioteca 4, 95124 Catania (Italy)

    2016-02-15

    Imaging of the electron cyclotron resonance (ECR) plasmas by using CCD camera in combination with a pinhole is a non-destructive diagnostics method to record the strongly inhomogeneous spatial density distribution of the X-ray emitted by the plasma and by the chamber walls. This method can provide information on the location of the collisions between warm electrons and multiple charged ions/atoms, opening the possibility to investigate the direct effect of the ion source tuning parameters to the plasma structure. The first successful experiment with a pinhole X-ray camera was carried out in the Atomki ECR Laboratory more than 10 years ago. The goal of that experiment was to make the first ECR X-ray photos and to carry out simple studies on the effect of some setting parameters (magnetic field, extraction, disc voltage, gas mixing, etc.). Recently, intensive efforts were taken to investigate now the effect of different RF resonant modes to the plasma structure. Comparing to the 2002 experiment, this campaign used wider instrumental stock: CCD camera with a lead pinhole was placed at the injection side allowing X-ray imaging and beam extraction simultaneously. Additionally, Silicon Drift Detector (SDD) and High Purity Germanium (HPGe) detectors were installed to characterize the volumetric X-ray emission rate caused by the warm and hot electron domains. In this paper, detailed comparison study on the two X-ray camera and detector setups and also on the technical and scientific goals of the experiments is presented.

  16. X-ray pinhole camera setups used in the Atomki ECR Laboratory for plasma diagnostics.

    Science.gov (United States)

    Rácz, R; Biri, S; Pálinkás, J; Mascali, D; Castro, G; Caliri, C; Romano, F P; Gammino, S

    2016-02-01

    Imaging of the electron cyclotron resonance (ECR) plasmas by using CCD camera in combination with a pinhole is a non-destructive diagnostics method to record the strongly inhomogeneous spatial density distribution of the X-ray emitted by the plasma and by the chamber walls. This method can provide information on the location of the collisions between warm electrons and multiple charged ions/atoms, opening the possibility to investigate the direct effect of the ion source tuning parameters to the plasma structure. The first successful experiment with a pinhole X-ray camera was carried out in the Atomki ECR Laboratory more than 10 years ago. The goal of that experiment was to make the first ECR X-ray photos and to carry out simple studies on the effect of some setting parameters (magnetic field, extraction, disc voltage, gas mixing, etc.). Recently, intensive efforts were taken to investigate now the effect of different RF resonant modes to the plasma structure. Comparing to the 2002 experiment, this campaign used wider instrumental stock: CCD camera with a lead pinhole was placed at the injection side allowing X-ray imaging and beam extraction simultaneously. Additionally, Silicon Drift Detector (SDD) and High Purity Germanium (HPGe) detectors were installed to characterize the volumetric X-ray emission rate caused by the warm and hot electron domains. In this paper, detailed comparison study on the two X-ray camera and detector setups and also on the technical and scientific goals of the experiments is presented.

  17. DIAGNOSTIC SPECTROSCOPIQUE EN TEMPERATURE ELECTRONIQUE DES PLASMAS PHOTOIONISES

    Directory of Open Access Journals (Sweden)

    A. K Ferouani

    2009-12-01

    Full Text Available In this work, we are interested in the diagnostics in electronic temperature of a plasma purely photoionized, based on the intensity ration of lines emitted by ions helium-like, witch have an atomic number Z relatively small. We considered the three lines corresponding to the transitions starting from the excited levels 1s2l towards the fundamental level 1s2 1S0, like appropriate lines. More precisely, the line of resonance w due to the transition 1s2p 1P1 1s2 1 S0, the line of intercombinaison (x,y 1s2p 3 P2,1 1s2 1 S0 as well as prohibited line z due to the transition 1s2 3 S1 1s2 1 S0. These lines appear clearly in the spectra of astrophysical plasmas. As helium-like ion, we chose two, the oxygen O6+ (Z=8 and neon Ne8+ (Z=10. We carried out calculations of the ration of lines intensity G=(zxy/w of O6+ and Ne8+ according to the electronic temperature in the range going from 105 to 107 K. We will see that, like it was shown by Gabriel and Jordan in 1969, this intensity ration can be very sensitive to the temperature electronic and practically independent of the electronic density. Consequently, the ration G can be used to determine in a reliable way the electronic temperature of plasma observed.

  18. Computerized tomographic imaging for space plasma physics

    Science.gov (United States)

    Zhang, Yuhong; Coplan, Michael A.; Moore, John H.; Berenstein, Carlos A.

    1990-01-01

    The measurement of plasma electron velocity distribution functions as a problem in imaging and image reconstruction is considered. A model instrument that measures the integral of the distribution function along lines in velocity space is presented. This allows the use of the powerful mathematical and numerical methods that have recently been so successful in other areas of imaging. It is found that this approach leads to classes of instruments that are qualitatively different from contemporary designs. An investigation of different methods of reconstruction of the distribution function from integral measurements reveals that the mathematical tools appropriate to one particular imaging problem may be very different from those required to deal with another.

  19. A survey of medical diagnostic imaging technologies

    Energy Technology Data Exchange (ETDEWEB)

    Heese, V.; Gmuer, N.; Thomlinson, W.

    1991-10-01

    The fields of medical imaging and medical imaging instrumentation are increasingly important. The state-of-the-art continues to advance at a very rapid pace. In fact, various medical imaging modalities are under development at the National Synchrotron Light Source (such as MECT and Transvenous Angiography.) It is important to understand how these techniques compare with today's more conventional imaging modalities. The purpose of this report is to provide some basic information about the various medical imaging technologies currently in use and their potential developments as a basis for this comparison. This report is by no means an in-depth study of the physics and instrumentation of the various imaging modalities; instead, it is an attempt to provide an explanation of the physical bases of these techniques and their principal clinical and research capabilities.

  20. A survey of medical diagnostic imaging technologies

    Energy Technology Data Exchange (ETDEWEB)

    Heese, V.; Gmuer, N.; Thomlinson, W.

    1991-10-01

    The fields of medical imaging and medical imaging instrumentation are increasingly important. The state-of-the-art continues to advance at a very rapid pace. In fact, various medical imaging modalities are under development at the National Synchrotron Light Source (such as MECT and Transvenous Angiography.) It is important to understand how these techniques compare with today`s more conventional imaging modalities. The purpose of this report is to provide some basic information about the various medical imaging technologies currently in use and their potential developments as a basis for this comparison. This report is by no means an in-depth study of the physics and instrumentation of the various imaging modalities; instead, it is an attempt to provide an explanation of the physical bases of these techniques and their principal clinical and research capabilities.

  1. Radiation exposure from diagnostic imaging among patients with gastrointestinal disorders.

    LENUS (Irish Health Repository)

    Desmond, Alan N

    2012-03-01

    There are concerns about levels of radiation exposure among patients who undergo diagnostic imaging for inflammatory bowel disease (IBD), compared with other gastrointestinal (GI) disorders. We quantified imaging studies and estimated the cumulative effective dose (CED) of radiation received by patients with organic and functional GI disorders. We also identified factors and diagnoses associated with high CEDs.

  2. TPX diagnostics for tokamak operation, plasma control and machine protection

    Energy Technology Data Exchange (ETDEWEB)

    Edmonds, P.H. [Texas Univ., Austin, TX (United States). Fusion Research Center; Medley, S.S.; Young, K.M. [Princeton Univ., NJ (United States). Plasma Physics Lab.] [and others

    1995-08-01

    The diagnostics for TPX are at an early design phase, with emphasis on the diagnostic access interface with the major tokamak components. Account has to be taken of the very severe environment for diagnostic components located inside the vacuum vessel. The placement of subcontracts for the design and fabrication of the diagnostic systems is in process.

  3. Neutral Beam Injection for Plasma and Magnetic FieldDiagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Vainionpaa, Jaakko Hannes; Leung, Ka Ngo; Kwan, Joe W.; Levinton,Fred

    2007-08-01

    At the Lawrence Berkeley National Laboratory (LBNL) adiagnostic neutral beam injection system for measuring plasma parameters,flow velocity, and local magnetic field is being developed. High protonfraction and small divergence is essential for diagnostic neutral beams.In our design, a neutral hydrogen beam with an 8 cm x 11 cm (or smaller)elliptical beam spot at 2.5 m from the end of the extraction column isproduced. The beam will deliver up to 5 A of hydrogen beam to the targetwith a pulse width of ~;1 s, once every 1 - 2 min. The H1+ ion species ofthe hydrogen beamwill be over 90 percent. For this application, we havecompared two types of RF driven multicusp ion sources operating at 13.56MHz. The first one is an ion source with an external spiral antennabehind a dielectric RF-window. The second one uses an internal antenna insimilar ion source geometry. The source needs to generate uniform plasmaover a large (8 cm x 5 cm) extraction area. We expect that the ion sourcewith internal antenna will be more efficient at producing the desiredplasma density but might have the issue of limited antenna lifetime,depending on the duty factor. For both approaches there is a need forextra shielding to protect the dielectric materials from the backstreaming electrons. The source walls will be made of insulator materialsuch as quartz that has been observed to generate plasma with higheratomic fraction than sources with metal walls. The ion beam will beextracted and accelerated by a set of grids with slits, thus forming anarray of 6 sheet-shaped beamlets. The multiple grid extraction will beoptimized using computer simulation programs. Neutralization of the beamwill be done in neutralization chamber, which has over 70 percentneutralization efficiency.

  4. Diagnostic imaging analysis of the impacted mesiodens

    Energy Technology Data Exchange (ETDEWEB)

    Noh, Jeong Jun; Choi, Bo Ram; Jeong, Hwan Seok; Huh, Kyung Hoe; Yi, Won Jin; Heo, Min Suk; Lee, Sam Sun; Choi, Soon Chul [School of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    2010-06-15

    The research was performed to predict the three dimensional relationship between the impacted mesiodens and the maxillary central incisors and the proximity with the anatomic structures by comparing their panoramic images with the CT images. Among the patients visiting Seoul National University Dental Hospital from April 2003 to July 2007, those with mesiodens were selected (154 mesiodens of 120 patients). The numbers, shapes, orientation and positional relationship of mesiodens with maxillary central incisors were investigated in the panoramic images. The proximity with the anatomical structures and complications were investigated in the CT images as well. The sex ratio (M : F) was 2.28 : 1 and the mean number of mesiodens per one patient was 1.28. Conical shape was 84.4% and inverted orientation was 51.9%. There were more cases of anatomical structures encroachment, especially on the nasal floor and nasopalatine duct, when the mesiodens was not superimposed with the central incisor. There were, however, many cases of the nasopalatine duct encroachment when the mesiodens was superimpoised with the apical 1/3 of central incisor (52.6%). Delayed eruption (55.6%), crown rotation (66.7%) and crown resorption (100%) were observed when the mesiodens was superimposed with the crown of the central incisor. It is possible to predict three dimensional relationship between the impacted mesiodens and the maxillary central incisors in the panoramic images, but more details should be confirmed by the CT images when necessary.

  5. DIAGNOSTIC IMAGING OF THE THROWING ATHLETE’S SHOULDER

    OpenAIRE

    Malone, Terry; Hazle, Charles

    2013-01-01

    The diagnostic capabilities of advanced imaging have increasingly enabled clinicians to delineate between structural alterations and injuries more efficiently than ever before. These impressive gains have unfortunately begun to provide a reliance on imaging at the loss of quality in the clinical examination. Ideally, imaging of the shoulder complex is performed to confirm the provisional diagnosis developed from the history and clinical exam rather than to create such. This clinical commentar...

  6. Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

    Institute of Scientific and Technical Information of China (English)

    Huilan ZHANG; Daowen WANG

    2008-01-01

    Using the plasma aldosterone concentration to plasma renin activity ratio (PAC/PRA ratio) as the screening test of choice for primary aldosteronism in hypertensive patients, we studied the clinical character-istics and the diagnostic value of PAC/PRA ratio in primary aldosteronism. The plasma aldosterone concen-tration (PAC) and plasma renin activity (PRA) levels were measured by radioimmunoassay in 902 hypertensive patients from out-patient clinics or hospitals. One hundred and twenty-six suspected primary aldosteronism patients whose PAC/PRA ratio was > 25 ng/dL/ng/mL/ hr had a lamellar computed tomography (CT) scan in the adrenal gland and follow-up visits. The proportion of primary aldosteronism in hypertensive patients was 14% (126/902). There were 54 patients with unilateral or bilateral hyperplasia and 25 patients with adenoma according to the CT scan. 39% (49/126) of the patients with primary aldosteronism had hypokalemia. Twenty-five patients received surgical treatment. The efficacy and cure rates were 100% (25/25) and 48% (12/25), respect-ively. The effective rate of aldactone and the single-drug cure rate were 89% (48/54) and 24% (13/54), respectively. Primary aldosteronism affects over 10% of hypertensive patients in China. The PAC/PRA ratio can be considered as a routine screening test in hypertensives, especially resistant hypertensive patients and a high PAC/PRA ratio is an invaluable index in primary aldosteronism diagnosis.

  7. Serial data acquisition for the X-ray plasma diagnostics with selected GEM detector structures

    Science.gov (United States)

    Czarski, T.; Chernyshova, M.; Pozniak, K. T.; Kasprowicz, G.; Zabolotny, W.; Kolasinski, P.; Krawczyk, R.; Wojenski, A.; Zienkiewicz, P.

    2015-10-01

    The measurement system based on GEM—Gas Electron Multiplier detector is developed for X-ray diagnostics of magnetic confinement tokamak plasmas. The paper is focused on the measurement subject and describes the fundamental data processing to obtain reliable characteristics (histograms) useful for physicists. The required data processing have two steps: 1—processing in the time domain, i.e. events selections for bunches of coinciding clusters, 2—processing in the planar space domain, i.e. cluster identification for the given detector structure. So, it is the software part of the project between the electronic hardware and physics applications. The whole project is original and it was developed by the paper authors. The previous version based on 1-D GEM detector was applied for the high-resolution X-ray crystal spectrometer KX1 in the JET tokamak. The current version considers 2-D detector structures for the new data acquisition system. The fast and accurate mode of data acquisition implemented in the hardware in real time can be applied for the dynamic plasma diagnostics. Several detector structures with single-pixel sensors and multi-pixel (directional) sensors are considered for two-dimensional X-ray imaging. Final data processing is presented by histograms for selected range of position, time interval and cluster charge values. Exemplary radiation source properties are measured by the basic cumulative characteristics: the cluster position distribution and cluster charge value distribution corresponding to the energy spectra. A shorter version of this contribution is due to be published in PoS at: 1st EPS conference on Plasma Diagnostics

  8. Diagnostic Imaging for Dental Implant Therapy

    Directory of Open Access Journals (Sweden)

    Aishwarya Nagarajan

    2014-01-01

    Full Text Available Dental implant is a device made of alloplastic (foreign material implanted into the jaw bone beneath the mucosal layer to support a fixed or removable dental prosthesis. Dental implants are gaining immense popularity and wide acceptance because they not only replace lost teeth but also provide permanent restorations that do not interfere with oral function or speech or compromise the self-esteem of a patient. Appropriate treatment planning for replacement of lost teeth is required and imaging plays a pivotal role to ensure a satisfactory outcome. The development of pre-surgical imaging techniques and surgical templates helps the dentist place the implants with relative ease. This article focuses on various types of imaging modalities that have a pivotal role in implant therapy.

  9. Basis set expansion for inverse problems in plasma diagnostic analysis

    Science.gov (United States)

    Jones, B.; Ruiz, C. L.

    2013-07-01

    A basis set expansion method [V. Dribinski, A. Ossadtchi, V. A. Mandelshtam, and H. Reisler, Rev. Sci. Instrum. 73, 2634 (2002)], 10.1063/1.1482156 is applied to recover physical information about plasma radiation sources from instrument data, which has been forward transformed due to the nature of the measurement technique. This method provides a general approach for inverse problems, and we discuss two specific examples relevant to diagnosing fast z pinches on the 20-25 MA Z machine [M. E. Savage, L. F. Bennett, D. E. Bliss, W. T. Clark, R. S. Coats, J. M. Elizondo, K. R. LeChien, H. C. Harjes, J. M. Lehr, J. E. Maenchen, D. H. McDaniel, M. F. Pasik, T. D. Pointon, A. C. Owen, D. B. Seidel, D. L. Smith, B. S. Stoltzfus, K. W. Struve, W. A. Stygar, L. K. Warne, J. R. Woodworth, C. W. Mendel, K. R. Prestwich, R. W. Shoup, D. L. Johnson, J. P. Corley, K. C. Hodge, T. C. Wagoner, and P. E. Wakeland, in Proceedings of the Pulsed Power Plasma Sciences Conference (IEEE, 2007), p. 979]. First, Abel inversion of time-gated, self-emission x-ray images from a wire array implosion is studied. Second, we present an approach for unfolding neutron time-of-flight measurements from a deuterium gas puff z pinch to recover information about emission time history and energy distribution. Through these examples, we discuss how noise in the measured data limits the practical resolution of the inversion, and how the method handles discontinuities in the source function and artifacts in the projected image. We add to the method a propagation of errors calculation for estimating uncertainties in the inverted solution.

  10. Basis set expansion for inverse problems in plasma diagnostic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jones, B.; Ruiz, C. L. [Sandia National Laboratories, PO Box 5800, Albuquerque, New Mexico 87185 (United States)

    2013-07-15

    A basis set expansion method [V. Dribinski, A. Ossadtchi, V. A. Mandelshtam, and H. Reisler, Rev. Sci. Instrum. 73, 2634 (2002)] is applied to recover physical information about plasma radiation sources from instrument data, which has been forward transformed due to the nature of the measurement technique. This method provides a general approach for inverse problems, and we discuss two specific examples relevant to diagnosing fast z pinches on the 20–25 MA Z machine [M. E. Savage, L. F. Bennett, D. E. Bliss, W. T. Clark, R. S. Coats, J. M. Elizondo, K. R. LeChien, H. C. Harjes, J. M. Lehr, J. E. Maenchen, D. H. McDaniel, M. F. Pasik, T. D. Pointon, A. C. Owen, D. B. Seidel, D. L. Smith, B. S. Stoltzfus, K. W. Struve, W. A. Stygar, L. K. Warne, J. R. Woodworth, C. W. Mendel, K. R. Prestwich, R. W. Shoup, D. L. Johnson, J. P. Corley, K. C. Hodge, T. C. Wagoner, and P. E. Wakeland, in Proceedings of the Pulsed Power Plasma Sciences Conference (IEEE, 2007), p. 979]. First, Abel inversion of time-gated, self-emission x-ray images from a wire array implosion is studied. Second, we present an approach for unfolding neutron time-of-flight measurements from a deuterium gas puff z pinch to recover information about emission time history and energy distribution. Through these examples, we discuss how noise in the measured data limits the practical resolution of the inversion, and how the method handles discontinuities in the source function and artifacts in the projected image. We add to the method a propagation of errors calculation for estimating uncertainties in the inverted solution.

  11. Plenoptic Imaging for Three-Dimensional Particle Field Diagnostics.

    Energy Technology Data Exchange (ETDEWEB)

    Guildenbecher, Daniel Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hall, Elise Munz [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-06-01

    Plenoptic imaging is a promising emerging technology for single-camera, 3D diagnostics of particle fields. In this work, recent developments towards quantitative measurements of particle size, positions, and velocities are discussed. First, the technique is proven viable with measurements of the particle field generated by the impact of a water drop on a thin film of water. Next, well cont rolled experiments are used to verify diagnostic uncertainty. Finally, an example is presented of 3D plenoptic imaging of a laboratory scale, explosively generated fragment field.

  12. Automated spectral imaging for clinical diagnostics

    Science.gov (United States)

    Breneman, John; Heffelfinger, David M.; Pettipiece, Ken; Tsai, Chris; Eden, Peter; Greene, Richard A.; Sorensen, Karen J.; Stubblebine, Will; Witney, Frank

    1998-04-01

    Bio-Rad Laboratories supplies imaging equipment for many applications in the life sciences. As part of our effort to offer more flexibility to the investigator, we are developing a microscope-based imaging spectrometer for the automated detection and analysis of either conventionally or fluorescently labeled samples. Immediate applications will include the use of fluorescence in situ hybridization (FISH) technology. The field of cytogenetics has benefited greatly from the increased sensitivity of FISH producing simplified analysis of complex chromosomal rearrangements. FISH methods for identification lends itself to automation more easily than the current cytogenetics industry standard of G- banding, however, the methods are complementary. Several technologies have been demonstrated successfully for analyzing the signals from labeled samples, including filter exchanging and interferometry. The detection system lends itself to other fluorescent applications including the display of labeled tissue sections, DNA chips, capillary electrophoresis or any other system using color as an event marker. Enhanced displays of conventionally stained specimens will also be possible.

  13. Diagnostic imaging of shoulder rotator cuff lesions

    OpenAIRE

    Nogueira-Barbosa Marcello Henrique; Volpon José Batista; Elias Jr Jorge; Muccillo Gerson

    2002-01-01

    Shoulder rotator cuff tendon tears were evaluated with ultrasonography (US) and magnetic resonance imaging (MRI). Surgical or arthroscopical correlation were available in 25 cases. Overall costs were also considered. Shoulder impingement syndrome diagnosis was done on a clinical basis. Surgery or arthroscopy was considered when conservative treatment failure for 6 months, or when rotator cuff repair was indicated. Ultrasound was performed in 22 patients and MRI in 17 of the 25 patients. Sensi...

  14. First Results from a Coherence Imaging Diagnostic for the Compact Toroidal Hybrid

    Science.gov (United States)

    Ennis, D. A.; Hartwell, G. J.; Johnson, C. A.; Maurer, D. A.; Allen, S. L.

    2015-11-01

    An optical coherence imaging diagnostic is being commissioned for time-resolved measurements (~ 10 ms) of ion emissivity, velocity, and temperature in the Compact Toroidal Hybrid (CTH) experiment. The Coherence Imaging (CI) technique measures the spectral coherence of an emission line with an imaging interferometer of fixed delay. CI has a number of advantages when compared to dispersive Doppler spectroscopy, including higher throughput and the capability to provide 2D spectral images, making it advantageous for investigating the non-axisymmetric geometry of CTH plasmas. A spectral survey of the visible and ultraviolet emission for a range of CTH discharges has identified helium and carbon impurity lines that will be utilized for CI measurements in CTH. First CI measurements of He II (468.6 nm) emission from CTH plasmas will be presented along with interferograms from a calibration light source and details of the instrument design. Results from this diagnostic will aid in characterizing the equilibrium ion parameters in both the edge and core of CTH plasmas for planned island divertor and MHD mode-locking experiments. Work supported by USDoE grant DE-FG02-00ER54610.

  15. Development of diffractive XUV-VUV light extractors for fusion plasma diagnostic

    Science.gov (United States)

    Stutman, D.; Caravelli, G.; Delgado-Aparicio, L.; Finkenthal, M.; Tritz, K.; Kaita, R.; Roquemore, L.

    2009-11-01

    The diagnostic and control of next generation MFE and ICF fusion experiments will require optical light extractors capable of withstanding intense plasma and radiation exposure. A solution applicable from the XUV to the infrared is to use free-standing diffractive optics such as transmission gratings or zone plates. Here we present results on XUV-VUV diffractive extractors for the diagnostic of boundary MFE plasmas. For the VUV range we developed Si transmission gratings having 1 μm period, 5 μm thickness, 40% open fraction, 1x2 mm active area, and coated with Ni, while for the XUV range we use SiN gratings having 0.2 μm period, 0.3 μm thickness, 1x1 mm area, and coated with Ta. The grating extractors are spectrally and spatially calibrated in the laboratory using a newly developed extended XUV-VUV source and will be employed for imaging spectrometry on the NSTX experiment. The operational characteristics of the extended source and first space resolved XUV-VUV spectra will be presented. Work supported by DoE Grant DE-FG02-99ER54523 at JHU and Contract DE-AC02-09CH11466 at PU.

  16. A review of diagnostic imaging of snakes and lizards.

    Science.gov (United States)

    Banzato, T; Hellebuyck, T; Van Caelenberg, A; Saunders, J H; Zotti, A

    2013-07-13

    Snakes and lizards are considered 'stoic' animals and often show only non-specific signs of illness. Consequently, diagnostic imaging--along with clinical examination and laboratory tests--is gaining importance in making a final diagnosis and establishing a correct therapy. The large number of captive snake and lizard species commonly kept as pets, together with the high inter- and intraspecific morphological variability that is innate in these animals, make the analysis of diagnostic images challenging for the veterinary practitioner. Moreover, a thorough knowledge of the anatomy, physiology and pathology of the species that are the object of clinical investigation is mandatory for the correct interpretation of diagnostic images. Despite the large amount of clinical and scientific work carried out in the past two decades, the radiographic features of snakes and lizards have not undergone systematic description, and therefore veterinarians often have to rely mostly on anatomical studies rather than radiological literature. The aim of this paper is to review the most commonly used diagnostic imaging modalities, as well as to provide an overview of the available international original studies and scientific reviews describing the normal and pathological imaging features in snakes and lizards.

  17. Non-invasive diagnostic imaging of colorectal liver metastases

    Institute of Scientific and Technical Information of China (English)

    Pier; Paolo; Mainenti; Federica; Romano; Laura; Pizzuti; Sabrina; Segreto; Giovanni; Storto; Lorenzo; Mannelli; Massimo; Imbriaco; Luigi; Camera; Simone; Maurea

    2015-01-01

    Colorectal cancer is one of the few malignant tumors in which synchronous or metachronous liver metastases [colorectal liver metastases(CRLMs)] may be treated with surgery. It has been demonstrated that resection of CRLMs improves the long-term prognosis. On the other hand, patients with un-resectable CRLMs may benefit from chemotherapy alone or in addition to liverdirected therapies. The choice of the most appropriate therapeutic management of CRLMs depends mostly on the diagnostic imaging. Nowadays, multiple non-invasive imaging modalities are available and those have a pivotal role in the workup of patients with CRLMs. Although extensive research has been performed with regards to the diagnostic performance of ultrasonography, computed tomography, positron emission tomography and magnetic resonance for the detection of CRLMs, the optimal imaging strategies for staging and follow up are still to be established. This largely due to the progressive technological and pharmacological advances which are constantly improving the accuracy of each imaging modality. This review describes the non-invasive imaging approaches of CRLMs reporting the technical features, the clinical indications, the advantages and the potential limitations of each modality, as well as including some information on the development of new imaging modalities, the role of new contrast media and the feasibility of using parametric image analysis as diagnostic marker of presence of CRLMs.

  18. Non-invasive diagnostic imaging of colorectal liver metastases.

    Science.gov (United States)

    Mainenti, Pier Paolo; Romano, Federica; Pizzuti, Laura; Segreto, Sabrina; Storto, Giovanni; Mannelli, Lorenzo; Imbriaco, Massimo; Camera, Luigi; Maurea, Simone

    2015-07-28

    Colorectal cancer is one of the few malignant tumors in which synchronous or metachronous liver metastases [colorectal liver metastases (CRLMs)] may be treated with surgery. It has been demonstrated that resection of CRLMs improves the long-term prognosis. On the other hand, patients with un-resectable CRLMs may benefit from chemotherapy alone or in addition to liver-directed therapies. The choice of the most appropriate therapeutic management of CRLMs depends mostly on the diagnostic imaging. Nowadays, multiple non-invasive imaging modalities are available and those have a pivotal role in the workup of patients with CRLMs. Although extensive research has been performed with regards to the diagnostic performance of ultrasonography, computed tomography, positron emission tomography and magnetic resonance for the detection of CRLMs, the optimal imaging strategies for staging and follow up are still to be established. This largely due to the progressive technological and pharmacological advances which are constantly improving the accuracy of each imaging modality. This review describes the non-invasive imaging approaches of CRLMs reporting the technical features, the clinical indications, the advantages and the potential limitations of each modality, as well as including some information on the development of new imaging modalities, the role of new contrast media and the feasibility of using parametric image analysis as diagnostic marker of presence of CRLMs.

  19. DIAGNOSTIC IMAGING OF THE THROWING ATHLETE’S SHOULDER

    Science.gov (United States)

    Hazle, Charles

    2013-01-01

    The diagnostic capabilities of advanced imaging have increasingly enabled clinicians to delineate between structural alterations and injuries more efficiently than ever before. These impressive gains have unfortunately begun to provide a reliance on imaging at the loss of quality in the clinical examination. Ideally, imaging of the shoulder complex is performed to confirm the provisional diagnosis developed from the history and clinical exam rather than to create such. This clinical commentary will provide the framework for both basic and advanced uses of imaging as well as discussion of evolving modalities. Level of Evidence: 5 PMID:24175143

  20. Advances in the diagnostic imaging of pheochromocytomas

    Directory of Open Access Journals (Sweden)

    Forssell-Aronsson E

    2011-05-01

    Full Text Available Eva Forssell-Aronsson1, Emil Schüler1, Håkan Ahlman21Department of Radiation Physics, 2Department of Surgery, Lundberg Laboratory of Cancer Research, Institute of Clinical Sciences, Sahlgrenska Academy at the University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, SwedenAbstract: Pheochromocytomas (PCs and paragangliomas (PGLs are routinely localized by computed tomography (CT, magnetic resonance imaging (MRI, and metaiodobenzylguanidine (MIBG scintigraphy. CT can identify tumors with high sensitivity but rather low specificity. MRI has higher sensitivity and specificity than CT and is superior to detect extra-adrenal disease. Radioiodinated MIBG scintigraphy has been used for more than 30 years and is based on MIBG uptake via the norepinephrine transporter on the cell membrane. The technique is very useful for whole-body studies in case of multiple primary tumors or metastases. Tumors with sole production of dopamine usually cannot be visualized with MIBG and may require positron emission tomographic (PET studies with 18F-labeled radiotracers. Somatostatin receptor scintigraphy (SRS using the radiolabeled somatostatin analog octreotide (based on the expression of the somatostatin receptors 2 and 5 by the tumor can demonstrate PGL or metastases not visualized by MIBG. In this article, we review the use of MIBG scintigraphy to diagnose PC/PGL and compare the sensitivity and specificity with that of CT and MRI. We also describe the recent SRS and PET techniques and review the latest results of clinical studies by comparing these imaging modalities. Future perspectives of functional imaging modalities for PC/PGL are finally presented.Keywords: MIBG, scintigraphy, pheochromocytoma, paraganglioma, PET

  1. 76 FR 77834 - Scientific Information Request on Intravascular Diagnostic and Imaging Medical Devices

    Science.gov (United States)

    2011-12-14

    ... Intravascular Diagnostic and Imaging Medical Devices AGENCY: Agency for Healthcare Research and Quality (AHRQ... intravascular diagnostic and imaging medical devices, including: Fractional Flow Reserve (FFR), Coronary Flow... Resonance Imaging (MRI), Elastrography, and Thermography. Scientific information is being solicited to...

  2. Diagnostic imaging of acute pulmonary embolism.

    Science.gov (United States)

    Christiansen, F

    1997-01-01

    The common strategy of combining clinical information, lung scintigraphy and pulmonary angiography in the diagnosis of acute pulmonary embolism (PE), has many limitations in clinical use. The major causes are that pulmonary angiography and lung scintigraphy are not universally available, and that pulmonary angiography is very expensive. The purpose of this thesis was to analyse different aspects of validity in regard to lung scintigraphy, pulmonary angiography, spiral CT, and ultrasound of the legs, with the subsequent intention of discussing new diagnostic strategies. Observer variations in lung scintigraphy interpretation when applying the PIOPED criteria were tested in 2 studies with 2 and 3 observers respectively and expressed as kappa values. The ability to improve agreement in lung scintigraphy interpretation was tested by training 2 observers from different hospitals. The impact of 3 observers' variations in lung scintigraphy interpretation when compared to pulmonary angiography, was tested by comparing the ROC areas of the observers. The value of combining subjectively derived numerical probabilities and the PIOPED categorical probabilities in lung scintigraphy reporting was compared to using the PIOPED categorization only, and this was tested by comparing ROC areas. The sensitivity and specificity of detecting an embolic source in the deep veins of the legs by ultrasound as a sign of PE when lung scintigraphy is inconclusive, was tested by comparison with pulmonary angiography. The sensitivity and specificity of spiral CT, compared to pulmonary angiography, was tested by comparison to pulmonary angiography. The inter- and intra-observer kappa values were in the range of moderate and fair. It was not possible to achieve better kappa values after training. Although observer variations were substantial, the accuracy did not differ significantly between the 3 observers. Incoorporating subjectively derived probabilities into lung scan reporting could not reduce

  3. Diagnostic value of imaging in infective endocarditis: a systematic review.

    Science.gov (United States)

    Gomes, Anna; Glaudemans, Andor W J M; Touw, Daan J; van Melle, Joost P; Willems, Tineke P; Maass, Alexander H; Natour, Ehsan; Prakken, Niek H J; Borra, Ronald J H; van Geel, Peter Paul; Slart, Riemer H J A; van Assen, Sander; Sinha, Bhanu

    2017-01-01

    Sensitivity and specificity of the modified Duke criteria for native valve endocarditis are both suboptimal, at approximately 80%. Diagnostic accuracy for intracardiac prosthetic material-related infection is even lower. Non-invasive imaging modalities could potentially improve diagnosis of infective endocarditis; however, their diagnostic value is unclear. We did a systematic literature review to critically appraise the evidence for the diagnostic performance of these imaging modalities, according to PRISMA and GRADE criteria. We searched PubMed, Embase, and Cochrane databases. 31 studies were included that presented original data on the performance of electrocardiogram (ECG)-gated multidetector CT angiography (MDCTA), ECG-gated MRI, (18)F-fluorodeoxyglucose ((18)F-FDG) PET/CT, and leucocyte scintigraphy in diagnosis of native valve endocarditis, intracardiac prosthetic material-related infection, and extracardiac foci in adults. We consistently found positive albeit weak evidence for the diagnostic benefit of (18)F-FDG PET/CT and MDCTA. We conclude that additional imaging techniques should be considered if infective endocarditis is suspected. We propose an evidence-based diagnostic work-up for infective endocarditis including these non-invasive techniques. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Cerebrovascular diagnostics - Imaging; Zerebrale Gefaessdiagnostik - Bildgebung

    Energy Technology Data Exchange (ETDEWEB)

    Roth, C. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg (Germany)

    2012-12-15

    Imaging of the cerebral vasculature relies mostly on computed tomography angiography (CTA), magnetic resonance angiography (MRA) and digital subtraction angiography (DSA). Although DSA is still the gold standard, many questions can be answered with CTA and/or MRA thanks to recent technological advances. The following article describes the advantages and disadvantages of these techniques with regard to different questions. Basic principles regarding the different techniques are explained. (orig.) [German] Die Bildgebung der zerebralen Gefaesse stuetzt sich im Wesentlichen auf die CT-Angiographie (CTA), MR-Angiographie (MRA) und die digitale Subtraktionsangiographie (DSA). Obwohl die DSA nach wie vor als Goldstandard gilt, lassen sich durch die technischen Neuerungen der Schnittbilddiagnostik viele Fragestellungen mithilfe von CTA und MR-A beantworten. Im nachfolgenden Artikel werden im Hinblick auf verschiedene Fragestellungen Vor- und Nachteile der einzelnen Verfahren aufgefuehrt sowie Grundlagen zu den einzelnen Techniken erlaeutert. (orig.)

  5. Diagnostic imaging advances in murine models of colitis.

    Science.gov (United States)

    Brückner, Markus; Lenz, Philipp; Mücke, Marcus M; Gohar, Faekah; Willeke, Peter; Domagk, Dirk; Bettenworth, Dominik

    2016-01-21

    Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are chronic-remittent inflammatory disorders of the gastrointestinal tract still evoking challenging clinical diagnostic and therapeutic situations. Murine models of experimental colitis are a vital component of research into human IBD concerning questions of its complex pathogenesis or the evaluation of potential new drugs. To monitor the course of colitis, to the present day, classical parameters like histological tissue alterations or analysis of mucosal cytokine/chemokine expression often require euthanasia of animals. Recent advances mean revolutionary non-invasive imaging techniques for in vivo murine colitis diagnostics are increasingly available. These novel and emerging imaging techniques not only allow direct visualization of intestinal inflammation, but also enable molecular imaging and targeting of specific alterations of the inflamed murine mucosa. For the first time, in vivo imaging techniques allow for longitudinal examinations and evaluation of intra-individual therapeutic response. This review discusses the latest developments in the different fields of ultrasound, molecularly targeted contrast agent ultrasound, fluorescence endoscopy, confocal laser endomicroscopy as well as tomographic imaging with magnetic resonance imaging, computed tomography and fluorescence-mediated tomography, discussing their individual limitations and potential future diagnostic applications in the management of human patients with IBD.

  6. Diagnostic Medical Imaging in Pediatric Patients and Subsequent Cancer Risk.

    Science.gov (United States)

    Mulvihill, David J; Jhawar, Sachin; Kostis, John B; Goyal, Sharad

    2017-06-20

    The use of diagnostic medical imaging is becoming increasingly more commonplace in the pediatric setting. However, many medical imaging modalities expose pediatric patients to ionizing radiation, which has been shown to increase the risk of cancer development in later life. This review article provides a comprehensive overview of the available data regarding the risk of cancer development following exposure to ionizing radiation from diagnostic medical imaging. Attention is paid to modalities such as computed tomography scans and fluoroscopic procedures that can expose children to radiation doses orders of magnitude higher than standard diagnostic x-rays. Ongoing studies that seek to more precisely determine the relationship of diagnostic medical radiation in children and subsequent cancer development are discussed, as well as modern strategies to better quantify this risk. Finally, as cardiovascular imaging and intervention contribute substantially to medical radiation exposure, we discuss strategies to enhance radiation safety in these areas. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  7. Early diagnostic method for sepsis based on neutrophil MR imaging

    Directory of Open Access Journals (Sweden)

    Shanhua Han

    2015-06-01

    Conclusion: Mouse and human neutrophils could be more effectively labelled by Mannan-coated SPION in vitro than Feridex. Sepsis analog neutrophils labelled by Mannan-coated SPIONs could be efficiently detected on MR images, which may serve as an early diagnostic method for sepsis.

  8. Second Topical Conference on High-Temperature Plasma Diagnostics

    Science.gov (United States)

    1978-02-01

    1 and is employed to make routine measurements of the evolution of plasma density in the high density ( n > 5 x 1011* cm-3) Alcator A tokamak...plasmas. To exemplify the use of these techniques in fusion plasmas, studies of density fluc- tuations in the ATC and ALCATOR tokamaks will be...character- istics for the excessive incidence of plasma light. Video signals are recorded with a video tape recorder, which starts and stops recording

  9. Advancements in electron cyclotron emission imaging demonstrated by the TEXTOR ECEI diagnostic upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Tobias, B.; Kong, X.; Liang, T.; Spear, A.; Domier, C. W.; Luhmann, N. C. Jr. [University of California at Davis, Davis, California 95616 (United States); Classen, I. G. J.; Boom, J. E.; Pol, M. J. van de; Jaspers, R.; Donne, A. J. H. [Association EURATOM-FOM, FOM Institute for Plasma Physics Rijnhuizen, Trilateral Euregio Cluster, 3430 BE Nieuwegein (Netherlands); Park, H. K. [Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784 (Korea, Republic of); Munsat, T. [University of Colorado at Boulder, Boulder, Colorado 80309 (United States)

    2009-09-15

    A new TEXTOR electron cyclotron emission imaging system has been developed and employed, providing a diagnostic with new features and enhanced capabilities when compared to the legacy system it replaces. Optical coupling to the plasma has been completely redesigned, making use of new minilens arrays for reduced optical aberration and providing the new feature of vertical zoom, whereby the vertical coverage is now remotely adjustable on a shot-by-shot basis from 20-35 cm. Other innovations, such as the implementation of stacked quasioptical planar notch filters, allow for the diagnostic to be operated without interruption or degradation in performance during electron cyclotron resonance heating. Successful commissioning of the new diagnostic and a demonstration of the improved capabilities are presented in this paper, along with a discussion of the new technologies employed.

  10. Present status on atomic and molecular data relevant to fusion plasma diagnostics and modeling

    Energy Technology Data Exchange (ETDEWEB)

    Tawara, H. [ed.

    1997-01-01

    This issue is the collection of the paper presented status on atomic and molecular data relevant to fusion plasma diagnostics and modeling. The 10 of the presented papers are indexed individually. (J.P.N.)

  11. Phyllodes tumor: diagnostic imaging and histopathology findings.

    Science.gov (United States)

    Venter, Alina Cristiana; Roşca, Elena; Daina, Lucia Georgeta; Muţiu, Gabriela; Pirte, Adriana Nicoleta; Rahotă, Daniela

    2015-01-01

    Phyllodes tumors are rare breast tumors, accounting for less than 1% of all primary tumors of the breast. Histologically, phyllodes tumors can be divided into benign (60%), borderline (20%) and malignant (20%). The mammography examination was performed by means of a digital mammography system Giotto 3D Images; the ultrasound examination was performed through a GE Logiq P6 device and histological confirmation was possible after surgery or following the histological biopsy. We grouped the nine patients who presented clinically palpable nodules into two groups, namely: the six patients presenting histological benign results into Group I, and Group II where we included those with borderline and malignant histological results. Mammography performed in 77.7% revealed a well-circumscribed round or oval opacity or with contour lobules. Ultrasound examination was performed in all patients. Mammography and ultrasound have limitation in differentiating between benign lesion and phyllodes tumor. In the nine analyzed cases, mammographic and ultrasound examinations did not allow the differentiation into the three groups of phyllodes tumor. Histopathological examination is considered the golden standard for their diagnosis. Correlations between mammographic and microscopic aspects were inconclusive for determining the degree of differentiation, ultrasound changes could be correlated with the histopathological aspects.

  12. Diagnostic imaging of shoulder rotator cuff lesions

    Directory of Open Access Journals (Sweden)

    Nogueira-Barbosa Marcello Henrique

    2002-01-01

    Full Text Available Shoulder rotator cuff tendon tears were evaluated with ultrasonography (US and magnetic resonance imaging (MRI. Surgical or arthroscopical correlation were available in 25 cases. Overall costs were also considered. Shoulder impingement syndrome diagnosis was done on a clinical basis. Surgery or arthroscopy was considered when conservative treatment failure for 6 months, or when rotator cuff repair was indicated. Ultrasound was performed in 22 patients and MRI in 17 of the 25 patients. Sensitivity, specificity and accuracy were 80%, 100% and 90.9% for US and 90%, 100% and 94.12% for MRI, respectively. In 16 cases both US and MRI were obtained and in this subgroup statistical correlation was excellent (p< 0.001. We concluded that both methods are reliable for rotator cuff full thickness tear evaluation. Since US is less expensive, it could be considered as the screening method when rotator cuff integrity is the main question, and when well trained radiologists and high resolution equipment are available.

  13. 3D ultrasound imaging for prosthesis fabrication and diagnostic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Morimoto, A.K.; Bow, W.J.; Strong, D.S. [and others

    1995-06-01

    The fabrication of a prosthetic socket for a below-the-knee amputee requires knowledge of the underlying bone structure in order to provide pressure relief for sensitive areas and support for load bearing areas. The goal is to enable the residual limb to bear pressure with greater ease and utility. Conventional methods of prosthesis fabrication are based on limited knowledge about the patient`s underlying bone structure. A 3D ultrasound imaging system was developed at Sandia National Laboratories. The imaging system provides information about the location of the bones in the residual limb along with the shape of the skin surface. Computer assisted design (CAD) software can use this data to design prosthetic sockets for amputees. Ultrasound was selected as the imaging modality. A computer model was developed to analyze the effect of the various scanning parameters and to assist in the design of the overall system. The 3D ultrasound imaging system combines off-the-shelf technology for image capturing, custom hardware, and control and image processing software to generate two types of image data -- volumetric and planar. Both volumetric and planar images reveal definition of skin and bone geometry with planar images providing details on muscle fascial planes, muscle/fat interfaces, and blood vessel definition. The 3D ultrasound imaging system was tested on 9 unilateral below-the- knee amputees. Image data was acquired from both the sound limb and the residual limb. The imaging system was operated in both volumetric and planar formats. An x-ray CT (Computed Tomography) scan was performed on each amputee for comparison. Results of the test indicate beneficial use of ultrasound to generate databases for fabrication of prostheses at a lower cost and with better initial fit as compared to manually fabricated prostheses.

  14. Autofluorescence-based diagnostic UV imaging of tissues and cells

    Science.gov (United States)

    Renkoski, Timothy E.

    Cancer is the second leading cause of death in the United States, and its early diagnosis is critical to improving treatment options and patient outcomes. In autofluorescence (AF) imaging, light of controlled wavelengths is projected onto tissue, absorbed by specific molecules, and re-emitted at longer wavelengths. Images of re-emitted light are used together with spectral information to infer tissue functional information and diagnosis. This dissertation describes AF imaging studies of three different organs using data collected from fresh human surgical specimens. In the ovary study, illumination was at 365 nm, and images were captured at 8 emission wavelengths. Measurements from a multispectral imaging system and fiber optic probe were used to map tissue diagnosis at every image pixel. For the colon and pancreas studies, instrumentation was developed extending AF imaging capability to sub-300 nm excitation. Images excited in the deep UV revealed tryptophan and protein content which are believed to change with disease state. Several excitation wavelength bands from 280 nm to 440 nm were investigated. Microscopic AF images collected in the pancreas study included both cultured and primary cells. Several findings are reported. A method of transforming fiber optic probe spectra for direct comparison with imager spectra was devised. Normalization of AF data by green reflectance data was found useful in correcting hemoglobin absorption. Ratio images, both AF and reflectance, were formulated to highlight growths in the colon. Novel tryptophan AF images were found less useful for colon diagnostics than the new ratio techniques. Microscopic tryptophan AF images produce useful visualization of cellular protein content, but their diagnostic value requires further study.

  15. Upgrade of the automatic analysis system in the TJ-II Thomson Scattering diagnostic: New image recognition classifier and fault condition detection

    NARCIS (Netherlands)

    Makili, L.; Vega, J.; Dormido-Canto, S.; Pastor, I.; Pereira, A.; Farias, G.; Portas, A.; Perez-Risco, D.; Rodriguez-Fernandez, M. C.; Busch, P.

    2010-01-01

    An automatic image classification system based on support vector machines (SVM) has been in operation for years in the TJ-II Thomson Scattering diagnostic. It recognizes five different types of images: CCD camera background, measurement of stray light without plasma or in a collapsed discharge, imag

  16. Diagnostic imaging in psychiatry; Bildgebende Verfahren in der Psychiatrie

    Energy Technology Data Exchange (ETDEWEB)

    Stoppe, G.; Hentschel, F.; Munz, D.L. (eds.)

    2000-07-01

    The textbook presents an exhaustive survey of diagnostic imaging methods available for clinical evaluation of the entire range of significant psychiatric symptoms via imaging of the anatomy and functions of the brain. The chapters discuss: The methods and their efficient use for given diagnostic objectives, image analysis, description and interpretation of findings with respect to the clinical symptoms. Morphology and functional correlation of findings. The book is intended to help psychiatrists and neurologists as well as doctors in the radiology and nuclear medicine departments. (orig./CB) [German] Die Entwicklung der modernen Bildgebung ermoeglicht faszinierende Einblicke in Anatomie und Funktionen des Gehirns und ihre Veraenderungen bei psychiatrischen Erkrankungen. Die Methodik der Untersuchungsverfahren und die Befunde bei allen wichtigen psychiatrischen Krankheitsbildern sind in diesem Buch systematisch und umfassend beschrieben: - gezielter und effizienter Einsatz der Verfahren, - Bildanalyse und Befundbeschreibung, - Bewertung der Befunde und Beziehung zum klinischen Bild, - morphologische und funktionelle Korrelate der Befunde. Psychiater und Neurologen werden ebenso angesprochen wie Radiologen und Nuklearmediziner. (orig.)

  17. Development, diagnostic and applications of radio-frequency plasma reactor

    Science.gov (United States)

    Puac, N.

    2008-07-01

    In many areas of the industry, plasma processing of materials is a vital technology. Nonequilibrium plasmas proved to be able to produce chemically reactive species at a low gas temperature while maintaining highly uniform reaction rates over relatively large areas (Makabe and Petrovic 2006). At the same time nonequilibrium plasmas provide means for good and precise control of the properties of active particles that determine the surface modification. Plasma needle is one of the atmospheric pressure sources that can be used for treatment of the living matter which is highly sensitive when it comes to low pressure or high temperatures (above 40 C). Dependent on plasma conditions, several refined cell responses are induced in mammalian cells (Sladek et al. 2005). It appears that plasma treatment may find many biomedical applications. However, there are few data in the literature about plasma effects on plant cells and tissues. So far, only the effect of low pressure plasmas on seeds was investigated. It was shown that short duration pretreatments by non equilibrium low temperature air plasma were stimulative in light induced germination of Paulownia tomentosa seeds (Puac et al. 2005). As membranes of plants have different properties to those of animals and as they show a wide range of properties we have tried to survey some of the effects of typical plasma which is envisaged to be used in biotechnological applications on plant cells. In this paper we will make a comparison between two configurations of plasma needle that we have used in treatment of biological samples (Puac et al. 2006). Difference between these two configurations is in the additional copper ring that we have placed around glass tube at the tip of the needle. We will show some of the electrical characteristics of the plasma needle (with and without additional copper ring) and, also, plasma emission intensity obtained by using fast ICCD camera.

  18. Plasma Diagnostic and Performance of a Permanent Magnet Hall Thruster

    CERN Document Server

    Ferreira, J L; Rego, I D S; Ferreira, I S; Ferreira, Jose Leonardo; Souza, Joao Henrique Campos De; Rego, Israel Da Silveira; Ferreira, Ivan Soares

    2004-01-01

    Electric propulsion is now a sucessfull method for primary propulsion of deep space long duration missions and for geosyncronous satellite attitude control. Closed Drift Plasma Thruster, so called Hall Thruster or SPT (stationary plasma thruster) were primarily conceived in USSR (the ancient Soviet Union) and now it is been developed by space agencies, space research institutes and industries in several countries such as France, USA, Israel, Russian Federation and Brazil. In this work, we show plasma characteristics and performance of a Hall Thruster designed with an innovative concept which uses an array of permanent magnets, instead of an eletromagnet, to produce a radial magnetic field inside its cylindrical plasma drift channel. Within this new concept, we expect to develop a Hall Thruster within power consuption that will scale up to small and medium size satellites. A plasma density and temperature space profiles inside and outside the thruster channel will be shown. Space plasma potential, ion temperat...

  19. Image standards in Tissue-Based Diagnosis (Diagnostic Surgical Pathology

    Directory of Open Access Journals (Sweden)

    Vollmer Ekkehard

    2008-04-01

    Full Text Available Abstract Background Progress in automated image analysis, virtual microscopy, hospital information systems, and interdisciplinary data exchange require image standards to be applied in tissue-based diagnosis. Aims To describe the theoretical background, practical experiences and comparable solutions in other medical fields to promote image standards applicable for diagnostic pathology. Theory and experiences Images used in tissue-based diagnosis present with pathology – specific characteristics. It seems appropriate to discuss their characteristics and potential standardization in relation to the levels of hierarchy in which they appear. All levels can be divided into legal, medical, and technological properties. Standards applied to the first level include regulations or aims to be fulfilled. In legal properties, they have to regulate features of privacy, image documentation, transmission, and presentation; in medical properties, features of disease – image combination, human – diagnostics, automated information extraction, archive retrieval and access; and in technological properties features of image acquisition, display, formats, transfer speed, safety, and system dynamics. The next lower second level has to implement the prescriptions of the upper one, i.e. describe how they are implemented. Legal aspects should demand secure encryption for privacy of all patient related data, image archives that include all images used for diagnostics for a period of 10 years at minimum, accurate annotations of dates and viewing, and precise hardware and software information. Medical aspects should demand standardized patients' files such as DICOM 3 or HL 7 including history and previous examinations, information of image display hardware and software, of image resolution and fields of view, of relation between sizes of biological objects and image sizes, and of access to archives and retrieval. Technological aspects should deal with image

  20. Image standards in tissue-based diagnosis (diagnostic surgical pathology).

    Science.gov (United States)

    Kayser, Klaus; Görtler, Jürgen; Goldmann, Torsten; Vollmer, Ekkehard; Hufnagl, Peter; Kayser, Gian

    2008-04-18

    Progress in automated image analysis, virtual microscopy, hospital information systems, and interdisciplinary data exchange require image standards to be applied in tissue-based diagnosis. To describe the theoretical background, practical experiences and comparable solutions in other medical fields to promote image standards applicable for diagnostic pathology. THEORY AND EXPERIENCES: Images used in tissue-based diagnosis present with pathology-specific characteristics. It seems appropriate to discuss their characteristics and potential standardization in relation to the levels of hierarchy in which they appear. All levels can be divided into legal, medical, and technological properties. Standards applied to the first level include regulations or aims to be fulfilled. In legal properties, they have to regulate features of privacy, image documentation, transmission, and presentation; in medical properties, features of disease-image combination, human-diagnostics, automated information extraction, archive retrieval and access; and in technological properties features of image acquisition, display, formats, transfer speed, safety, and system dynamics. The next lower second level has to implement the prescriptions of the upper one, i.e. describe how they are implemented. Legal aspects should demand secure encryption for privacy of all patient related data, image archives that include all images used for diagnostics for a period of 10 years at minimum, accurate annotations of dates and viewing, and precise hardware and software information. Medical aspects should demand standardized patients' files such as DICOM 3 or HL 7 including history and previous examinations, information of image display hardware and software, of image resolution and fields of view, of relation between sizes of biological objects and image sizes, and of access to archives and retrieval. Technological aspects should deal with image acquisition systems (resolution, colour temperature, focus

  1. Magnetic Diagnostics For Equilibrium Reconstruction And Realtime Plasma Control In NSTX-Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Gerhardt, Stefan P. [PPPL; Erickson, Keith [PPPL; Kaita, Robert [PPPL; Lawson, John [PPPL; Mozulay, Robert [PPPL; Mueller, Dennis [PPPL; Que, Weiguo [PPPL; Rahman, Nabidur [PPPL; Schneider, Hans [PPPL; Smalley, Gustav [PPPL; Tresemer, Kelsey [PPPL

    2014-06-01

    This paper describes aspects of magnetic diagnostics for realtime control in NSTX-U. The sensor arrangement on the upgraded center column is described. New analog and digital circuitry for processing the plasma current rogowski data are presented. An improved algorithm for estimating the plasma vertical velocity for feedback control is presented.

  2. Plasma diagnostics approach to welding heat source/molten pool interaction

    Energy Technology Data Exchange (ETDEWEB)

    Key, J.F.; McIlwain, M.E.; Isaacson, L.

    1980-01-01

    Plasma diagnostic techniques show that weld fusion zone profile and loss of metal vapors from the molten pool are strongly dependent on both the intensity and distribution of the heat source. These plasma properties, are functions of cathode vertex angle and thermal conductivity of the shielding gas, especially near the anode.

  3. HL-2A Tokamak Plasma Visible Light Imaging System

    Institute of Scientific and Technical Information of China (English)

    ZHENGYinjia; FENGZhen; LUOCuiwen; CHENGLiaoyuan

    2003-01-01

    Visible imagery is extremely useful to overview the edge and divertor structure. The plasma configuration and the position of the strike lines on the target plates can be also observed by imaging technique. By imaging the edge or core plasma with visible emission in the desired wavelength band, usually with a “tangential” view, the plasma position can be determined in principle.

  4. Computers in Diagnostic Nuclear Medicine Imaging - A Review

    Directory of Open Access Journals (Sweden)

    K. K. Kapoor

    1989-07-01

    Full Text Available Digital computers are becoming increasingly popular for a variety of purposes in nuclear medicine. They are particuiarly useful in the areas of nuclear imaging and gamma camera image processing,radionuclide inventory and patient record keeping. By far the most important use of the digital computer is in array processors which are commonly available with emission computed systems for fast reconstruction of images in transverse, coronal and sagittal views, particularly when the data to be handled is enormous and involves filtration and correction processes. The addition of array processors to computer systems has helped the clinicians in improving diagnostic nuclear medicine imaging capability. This paper reviews briefly therole of computers in the field of nuclear medicine imaging.

  5. Optimizing Patient-centered Communication and Multidisciplinary Care Coordination in Emergency Diagnostic Imaging: A Research Agenda.

    Science.gov (United States)

    Sabbatini, Amber K; Merck, Lisa H; Froemming, Adam T; Vaughan, William; Brown, Michael D; Hess, Erik P; Applegate, Kimberly E; Comfere, Nneka I

    2015-12-01

    Patient-centered emergency diagnostic imaging relies on efficient communication and multispecialty care coordination to ensure optimal imaging utilization. The construct of the emergency diagnostic imaging care coordination cycle with three main phases (pretest, test, and posttest) provides a useful framework to evaluate care coordination in patient-centered emergency diagnostic imaging. This article summarizes findings reached during the patient-centered outcomes session of the 2015 Academic Emergency Medicine consensus conference "Diagnostic Imaging in the Emergency Department: A Research Agenda to Optimize Utilization." The primary objective was to develop a research agenda focused on 1) defining component parts of the emergency diagnostic imaging care coordination process, 2) identifying gaps in communication that affect emergency diagnostic imaging, and 3) defining optimal methods of communication and multidisciplinary care coordination that ensure patient-centered emergency diagnostic imaging. Prioritized research questions provided the framework to define a research agenda for multidisciplinary care coordination in emergency diagnostic imaging.

  6. Healthcare provider and patient perspectives on diagnostic imaging investigations

    Science.gov (United States)

    Bergh, Anne-Marie; Hoffmann, Willem A.

    2015-01-01

    Background: Much has been written about the patient-centred approach in doctor–patient consultations. Little is known about interactions and communication processes regarding healthcare providers’ and patients’ perspectives on expectations and experiences of diagnostic imaging investigations within the medical encounter. Patients journey through the health system from the point of referral to the imaging investigation itself and then to the post-imaging consultation. Aim and setting: To explore healthcare provider and patient perspectives on interaction and communication processes during diagnostic imaging investigations as part of their clinical journey through a healthcare complex. Methods: A qualitative study was conducted, with two phases of data collection. Twenty-four patients were conveniently selected at a public district hospital complex and were followed throughout their journey in the hospital system, from admission to discharge. The second phase entailed focus group interviews conducted with providers in the district hospital and adjacent academic hospital (medical officers and family physicians, nurses, radiographers, radiology consultants and registrars). Results: Two main themes guided our analysis: (1) provider perspectives; and (2) patient dispositions and reactions. Golden threads that cut across these themes are interactions and communication processes in the context of expectations, experiences of the imaging investigations and the outcomes thereof. Conclusion: Insights from this study provide a better understanding of the complexity of the processes and interactions between providers and patients during the imaging investigations conducted as part of their clinical pathway. The interactions and communication processes are provider–patient centred when a referral for a diagnostic imaging investigation is included. PMID:26245604

  7. Combining a thermal-imaging diagnostic with an existing imaging VISAR diagnostic at the National Ignition Facility (NIF)

    Science.gov (United States)

    Malone, Robert M.; Celeste, John R.; Celliers, Peter M.; Frogget, Brent C.; Guyton, Robert L.; Kaufman, Morris I.; Lee, Tony L.; MacGowan, Brian J.; Ng, Edmund W.; Reinbachs, Imants P.; Robinson, Ronald B.; Seppala, Lynn G.; Tunnell, Thomas W.; Watts, Phillip W.

    2005-08-01

    Optical diagnostics are currently being designed to analyze high-energy density physics experiments at the National Ignition Facility (NIF). Two independent line-imaging Velocity Interferometer System for Any Reflector (VISAR) interferometers have been fielded to measure shock velocities, breakout times, and emission of targets having sizes of 1-5 mm. An 8-inch-diameter, fused silica triplet lens collects light at f/3 inside the 30-foot-diameter NIF vacuum chamber. VISAR recordings use a 659.5-nm probe laser. By adding a specially coated beam splitter to the interferometer table, light at wavelengths from 540 to 645 nm is spilt into a thermal-imaging diagnostic. Because fused silica lenses are used in the first triplet relay, the intermediate image planes for different wavelengths separate by considerable distances. A corrector lens on the interferometer table reunites these separated wavelength planes to provide a good image. Thermal imaging collects light at f/5 from a 2-mm object placed at Target Chamber Center (TCC). Streak cameras perform VISAR and thermal-imaging recording. All optical lenses are on kinematic mounts so that pointing accuracy of the optical axis may be checked. Counter-propagating laser beams (orange and red) are used to align both diagnostics. The red alignment laser is selected to be at the 50 percent reflection point of the beam splitter. This alignment laser is introduced at the recording streak cameras for both diagnostics and passes through this special beam splitter on its way into the NIF vacuum chamber.

  8. Combining a thermal-imaging diagnostic with an existing imaging VISAR diagnostic at the National Ignition Facility (NIF)

    Energy Technology Data Exchange (ETDEWEB)

    Robert M. Malone; John R. Celesteb; Peter M. Celliers; Brent C. Froggeta; Robert L. Guyton; Morris I. Kaufman; Tony L. Lee; Brian J. MacGowan; Edmund W. Ng; Imants P. Reinbachs; Ronald B. Robinson; Lynn G. Seppala; Tom W. Tunnell; Phillip W. Watts

    2005-01-01

    Optical diagnostics are currently being designed to analyze high-energy density physics experiments at the National Ignition Facility (NIF). Two independent line-imaging Velocity Interferometer System for Any Reflector (VISAR) interferometers have been fielded to measure shock velocities, breakout times, and emission of targets having sizes of 1–5 mm. An 8-inch-diameter, fused silica triplet lens collects light at f/3 inside the 30-foot-diameter NIF vacuum chamber. VISAR recordings use a 659.5-nm probe laser. By adding a specially coated beam splitter to the interferometer table, light at wavelengths from 540 to 645 nm is spilt into a thermal-imaging diagnostic. Because fused silica lenses are used in the first triplet relay, the intermediate image planes for different wavelengths separate by considerable distances. A corrector lens on the interferometer table reunites these separated wavelength planes to provide a good image. Thermal imaging collects light at f/5 from a 2-mm object placed at Target Chamber Center (TCC). Streak cameras perform VISAR and thermal-imaging recording. All optical lenses are on kinematic mounts so that pointing accuracy of the optical axis may be checked. Counter-propagating laser beams (orange and red) are used to align both diagnostics. The red alignment laser is selected to be at the 50 percent reflection point of the beam splitter. This alignment laser is introduced at the recording streak cameras for both diagnostics and passes through this special beam splitter on its way into the NIF vacuum chamber.

  9. Combining a thermal-imaging diagnostic with an existing imaging VISAR diagnostic at the National Ignition Facility (NIF)

    Energy Technology Data Exchange (ETDEWEB)

    Malone, R; Celeste, J; Celliers, P; Frogget, B; Guyton, R L; Kaufman, M; Lee, T; MacGowan, B; Ng, E W; Reinbachs, I P; Robinson, R B; Seppala, L; Tunnell, T W; Watts, P

    2005-07-07

    Optical diagnostics are currently being designed to analyze high-energy density physics experiments at the National Ignition Facility (NIF). Two independent line-imaging Velocity Interferometer System for Any Reflector (VISAR) interferometers have been fielded to measure shock velocities, breakout times, and emission of targets having sizes of 1-5 mm. An 8-inch-diameter, fused silica triplet lens collects light at f/3 inside the 30-foot-diameter NIF vacuum chamber. VISAR recordings use a 659.5-nm probe laser. By adding a specially coated beam splitter to the interferometer table, light at wavelengths from 540 to 645 nm is spilt into a thermal-imaging diagnostic. Because fused silica lenses are used in the first triplet relay, the intermediate image planes for different wavelengths separate by considerable distances. A corrector lens on the interferometer table reunites these separated wavelength planes to provide a good image. Thermal imaging collects light at f/5 from a 2-mm object placed at Target Chamber Center (TCC). Streak cameras perform VISAR and thermal-imaging recording. All optical lenses are on kinematic mounts so that pointing accuracy of the optical axis may be checked. Counter-propagating laser beams (orange and red) are used to align both diagnostics. The red alignment laser is selected to be at the 50 percent reflection point of the beam splitter. This alignment laser is introduced at the recording streak cameras for both diagnostics and passes through this special beam splitter on its way into the NIF vacuum chamber.

  10. Diagnostics of Femtosecond Laser-Plasmas Using Fundamental and Second Harmonic Emission

    Institute of Scientific and Technical Information of China (English)

    ZHAO Li-Zeng; ZHANG Ping; FENG Bao-Hua; WEI Zhi-Yi; ZHANG Jie

    2000-01-01

    By observing the fundamental and second harmonic emission from a plasma produced by a 150 fs, 5 mJ laser at 800nm, the electron temperature, the expansion speed and the scalelength of the plasma have been diagnosed. Moreover the polarization of the fundamental and second harmonic emission has been studied. This could be a useful diagnostic for modulation at the critical surface of the plasma.

  11. Millimeter-wave receiver design for plasma diagnostics

    DEFF Research Database (Denmark)

    Leipold, Frank; Hansen, S. K.; Jacobsen, Asger Schou;

    2016-01-01

    Scattered millimeter waves entering from the collective Thomson scattering diagnostic at ASDEX Upgrade fusion device are generally elliptically polarized. In order to convert the millimeter waves to linearly polarized waves (required for the detector), birefringent window assemblies (sapphire) have...

  12. X-ray plasma diagnostics for totally and partially photoionized plasmas such as Warm Absorber in AGN

    CERN Document Server

    Porquet, D; Porquet, Delphine; Dubau, Jacques

    1999-01-01

    Thanks to the new generation of X-ray satellites such as Chandra and XMM, high resolution and high sensitivity spectra are available. In particular, for the first time, the three most intense lines (resonance, intercombination and forbidden) of low charged (low Z) He-like ions are splitted for non solar plasmas. We present density, ionizing process and temperature diagnostics, for totally and partially photoionized plasmas, based on ratios of these three lines. These powerful plasma diagnostics could be used for hot astrophysical plasmas such as AGN, starburst galaxies, X-ray binaries, etc. In particular, they could be applied to Warm Absorber often seen in Active Galactic Nuclei (Porquet & Dubau 2000), which is an important key tool to understand central region of different types of AGN (Seyfert 1 and 2, high and low redshift quasars).

  13. Fusion plasma diagnostics with mm-waves an introduction

    CERN Document Server

    Hartfuss, Hans-Jürgen

    2013-01-01

    Filling a gap in the literature, this introduction to the topic covers the physics of the standard microwave diagnostics established on modern fusion experiments, and the necessary technological background from the field of microwave engineering. Written by well-known mm-wave diagnosticians in the field of fusion physics, the textbook includes such major diagnostic techniques as electron cyclotron emission, interferometry, reflectometry, polarimetry, and scattering.

  14. Electromagnetic analysis of ITER diagnostic equatorial port plugs during plasma disruptions

    Energy Technology Data Exchange (ETDEWEB)

    Zhai, Y., E-mail: yzhai@pppl.gov [Princeton Plasma Physics Laboratory, Princeton, NJ (United States); Feder, R.; Brooks, A. [Princeton Plasma Physics Laboratory, Princeton, NJ (United States); Ulrickson, M. [Sandia National Laboratory, Albuquerque, NM (United States); Pitcher, C.S. [ITER Organization, Route de Vinon sur Verdon, St Paul lez Durance (France); Loesser, G.D. [Princeton Plasma Physics Laboratory, Princeton, NJ (United States)

    2013-10-15

    Highlights: ► Disruption loads on ITER diagnostic equatorial port plugs are extracted. ► Upward major disruption produces the largest radial moment and radial force on diagnostic first walls and diagnostic shield modules. ► Large eddy currents on supporting rails, keys and water pipes are observed during disruption. -- Abstract: ITER diagnostic port plugs perform many functions including structural support of diagnostic systems under high electromagnetic loads while allowing for diagnostic access to the plasma. The design of diagnostic equatorial port plugs (EPP) are largely driven by electromagnetic loads and associate responses of EPP structure during plasma disruptions and VDEs. This paper summarizes results of transient electromagnetic analysis using Opera 3d in support of the design activities for ITER diagnostic EPP. A complete distribution of disruption loads on the diagnostic first walls (DFWs), diagnostic shield modules (DSMs) and the EPP structure, as well as impact on the system design integration due to electrical contact among various EPP structural components are discussed.

  15. Imaging VISAR diagnostic for the National Ignition Facility (NIF)

    Science.gov (United States)

    Malone, Robert M.; Bower, John R.; Bradley, David K.; Capelle, Gene A.; Celeste, John R.; Celliers, Peter M.; Collins, Gilbert W.; Eckart, Mark J.; Eggert, Jon H.; Frogget, Brent C.; Guyton, Robert L.; Hicks, Damien G.; Kaufman, Morris I.; MacGowan, Brian J.; Montelongo, Samuel; Ng, Edmund W.; Robinson, Ronald B.; Tunnell, Thomas W.; Watts, Phillip W.; Zapata, Paul G.

    2005-03-01

    The National Ignition Facility (NIF) requires diagnostics to analyze high-energy density physics experiments. A VISAR (Velocity Interferometry System for Any Reflector) diagnostic has been designed to measure shock velocities, shock breakout times, and shock emission of targets with sizes from 1 to 5 mm. An 8-inch-diameter fused silica triplet lens collects light at f/3 inside the 30-foot-diameter vacuum chamber. The optical relay sends the image out an equatorial port, through a 2-inch-thick vacuum window, and into two interferometers. A 60-kW VISAR probe laser operates at 659.5 nm with variable pulse width. Special coatings on the mirrors and cutoff filters are used to reject the NIF drive laser wavelengths and to pass a band of wavelengths for VISAR, passive shock breakout light, or thermal imaging light (bypassing the interferometers). The first triplet can be no closer than 500 mm from the target chamber center and is protected from debris by a blast window that is replaced after every event. The front end of the optical relay can be temporarily removed from the equatorial port, allowing other experimenters to use that port. A unique resolution pattern has been designed to validate the VISAR diagnostic before each use. All optical lenses are on kinematic mounts so that the pointing accuracy of the optical axis can be checked. Seven CCD cameras monitor the diagnostic alignment.

  16. Imaging VISAR diagnostic for the National Ignition Facility (NIF)

    Energy Technology Data Exchange (ETDEWEB)

    Malone, R M; Bower, J R; Bradley, D K; Capelle, G A; Celeste, J R; Celliers, P M; Collins, G W; Eckart, M J; Eggert, J H; Frogget, B C; Guyton, R L; Hicks, D G; Kaufman, M I; MacGowan, B J; Montelongo, S; Ng, E W; Robinson, R B; Tunnell, T W; Watts, P W; Zapata, P G

    2004-08-30

    The National Ignition Facility (NIF) requires diagnostics to analyze high-energy density physics experiments. A VISAR (Velocity Interferometry System for Any Reflector) diagnostic has been designed to measure shock velocities, shock breakout times, and shock emission of targets with sizes from 1 to 5 mm. An 8-inch-diameter fused silica triplet lens collects light at f/3 inside the 30-foot-diameter vacuum chamber. The optical relay sends the image out an equatorial port, through a 2-inch-thick vacuum window, and into two interferometers. A 60-kW VISAR probe laser operates at 659.5 nm with variable pulse width. Special coatings on the mirrors and cutoff filters are used to reject the NIF drive laser wavelengths and to pass a band of wavelengths for VISAR, passive shock breakout light, or thermal imaging light (bypassing the interferometers). The first triplet can be no closer than 500 mm from the target chamber center and is protected from debris by a blast window that is replaced after every event. The front end of the optical relay can be temporarily removed from the equatorial port, allowing other experimenters to use that port. A unique resolution pattern has been designed to validate the VISAR diagnostic before each use. All optical lenses are on kinematic mounts so that the pointing accuracy of the optical axis can be checked. Seven CCD cameras monitor the diagnostic alignment.

  17. Thermal imaging of plasma with a phased array antenna in QUEST

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, Kishore, E-mail: mishra@triam.kyushu-u.ac.jp; Nagata, K.; Akimoto, R.; Banerjee, S. [IGSES, Kyushu University, Kasuga, Fukuoka 816-8580 (Japan); Idei, H.; Zushi, H.; Hanada, K.; Hasegawa, M.; Nakamura, K.; Fujisawa, A.; Nagashima, Y.; Onchi, T.; Kuzmin, A. [RIAM, Kyushu University, Kasuga, Fukuoka 816-8580 (Japan); Yamamoto, M. K. [Research Institute for Sustainable Humanosphere, Kyoto University, Uji 611-0011 (Japan)

    2014-11-15

    A thermal imaging system to measure plasma Electron Bernstein Emission (EBE) emanating from the mode conversion region in overdense plasma is discussed. Unlike conventional ECE/EBE imaging, this diagnostics does not employ any active mechanical scanning mirrors or focusing optics to scan for the emission cones in plasma. Instead, a standard 3 × 3 waveguide array antenna is used as a passive receiver to collect emission from plasma and imaging reconstruction is done by accurate measurements of phase and intensity of these signals by heterodyne detection technique. A broadband noise source simulating the EBE, is installed near the expected mode conversion region and its position is successfully reconstructed using phase array technique which is done in post processing.

  18. Diagnostics of MCF plasmas using Lyman-{alpha} fluorescence excited by one or two photons

    Energy Technology Data Exchange (ETDEWEB)

    Voslamber, D

    1998-11-01

    Laser-induced Lyman-{alpha} fluorescence of the hydrogen isotopes is investigated with regard to diagnostic applications in magnetically confined fusion plasmas. A formal analysis is presented for two excitation schemes: one-photon and Doppler-free two-photon excitation. The analysis includes estimates of the expected experimental errors arising from the photon noise and from the sensitivity of the observed fluorescence signals to variations of the plasma and laser parameters. Both excitation schemes are suitable primarily for application in the plasma edge, but even in the plasma bulk of large machines they can still be applied in combination with a diagnostic neutral beam. The two-photon excitation scheme is particularly attractive because it involves absorption spectra that are resolved within the Doppler width. This implies a large diagnostic potential and in particular offers a way to measure the deuterium-tritium fuel mix in fusion reactors. (author) 37 refs.

  19. Spectroscopic diagnostics of plasma during laser processing of aluminium

    Science.gov (United States)

    Lober, R.; Mazumder, J.

    2007-10-01

    The role of the plasma in laser-metal interaction is of considerable interest due to its influence in the energy transfer mechanism in industrial laser materials processing. A 10 kW CO2 laser was used to study its interaction with aluminium under an argon environment. The objective was to determine the absorption and refraction of the laser beam through the plasma during the processing of aluminium. Laser processing of aluminium is becoming an important topic for many industries, including the automobile industry. The spectroscopic relative line to continuum method was used to determine the electron temperature distribution within the plasma by investigating the 4158 Å Ar I line emission and the continuum adjacent to it. The plasmas are induced in 1.0 atm pure Ar environment over a translating Al target, using f/7 and 10 kW CO2 laser. Spectroscopic data indicated that the plasma composition and behaviour were Ar-dominated. Experimental results indicated the plasma core temperature to be 14 000-15 300 K over the incident range of laser powers investigated from 5 to 7 kW. It was found that 7.5-29% of the incident laser power was absorbed by the plasma. Cross-section analysis of the melt pools from the Al samples revealed the absence of any key-hole formation and confirmed that the energy transfer mechanism in the targets was conduction dominated for the reported range of experimental data.

  20. Runaway electrons as a diagnostic of plasma internal magnetic fluctuations

    Institute of Scientific and Technical Information of China (English)

    Zheng Yong-Zhen; Ding Xuan-Tong; Li Wen-Zhong

    2006-01-01

    The transport of runaway electrons in a high-temperature plasma is relatively easy to measure in a steady state experiment and a perturbation experiment, which provides runaway electron diffusion coefficient Dr. This diffusion coefficient is determined by internal magnetic fluctuations, so it can be interpreted in terms of a magnetic fluctuation level. The internal magnetic fluctuation level (br/BT) is estimated to be about (2-4)×-4 in the HL-1M plasma. The results presented here demonstrate the effectiveness of using runaway electron transport techniques to determine internal magnetic fluctuations. A profile of magnetic fluctuation level in the HL-1M plasma can be estimated from Dr.

  1. Development and Integration of a Data Acquisition System for SST-1 Phase-1 Plasma Diagnostics

    Institute of Scientific and Technical Information of China (English)

    Amit K SRIVASTAVA; Manika SHARMA; Imran MANSURI; Atish SHARMA; Tushar RAVAL; Subrata PRADHAN

    2012-01-01

    Long pulse (of the order of 1000 s or more) SST-1 tokamak experiments demand a data acquisition system that is capable of acquiring data from various diagnostics channels without losing useful data (and hence physics information) while avoiding unnecessary generation of a large volume data. SST-1 Phase-1 tokamak operation has been envisaged with data acquisition of several essential diagnostics channels. These channels demand data acquisition at a sampling rate ranging from 1 kilo samples per second (KSPS) to 1 mega samples per second (MSPS). Considering the technical characteristics and requirements of the diagnostics, a data acquisition system based on PXI and CAMAC has been developed for SST-1 plasma diagnostics. Both these data acquisition systems are scalable. Present data acquisition needs involving slow plasma diagnostics are catered by the PXI based data acquisition system. On the other hand, CAMAC data acquisition hardware meets all requirements of the SST-1 Phase-1 fast plasma diagnostics channels. A graphical user interface for both data acquisition systems (PXI and CAMAC) has been developed using LabVIEW application development software. The collected data on the local hard disk are directly streaming to the central server through a dedicated network for post-shot data analysis. This paper describes the development and integration of the data acquisition system for SST-1 Phase-1 plasma diagnostics. The integrated testing of the developed data acquisition system has been performed using SST-1 central control and diagnostics signal conditioning units. In the absence of plasma shots, the integrated testing of the data acquisition system for the initial diagnostics of SST-1 Phase-1 operation has been performed with simulated physical signals. The primary engineering objective of this integrated testing is to validate the performance of the developed data acquisition system under simulated conditions close to that of actual tokamak operation. The data

  2. Parkinson's disease: diagnostic utility of volumetric imaging

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Wei-Che; Chen, Meng-Hsiang [Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Department of Diagnostic Radiology, Kaohsiung (China); Chou, Kun-Hsien [National Yang-Ming University, Brain Research Center, Taipei (China); Lee, Pei-Lin [National Yang-Ming University, Department of Biomedical Imaging and Radiological Sciences, Taipei (China); Tsai, Nai-Wen; Lu, Cheng-Hsien [Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Department of Neurology, Kaohsiung (China); Chen, Hsiu-Ling [Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Department of Diagnostic Radiology, Kaohsiung (China); National Yang-Ming University, Department of Biomedical Imaging and Radiological Sciences, Taipei (China); Hsu, Ai-Ling [National Taiwan University, Institute of Biomedical Electronics and Bioinformatics, Taipei (China); Huang, Yung-Cheng [Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Department of Nuclear Medicine, Kaohsiung (China); Lin, Ching-Po [National Yang-Ming University, Brain Research Center, Taipei (China); National Yang-Ming University, Department of Biomedical Imaging and Radiological Sciences, Taipei (China)

    2017-04-15

    This paper aims to examine the effectiveness of structural imaging as an aid in the diagnosis of Parkinson's disease (PD). High-resolution T{sub 1}-weighted magnetic resonance imaging was performed in 72 patients with idiopathic PD (mean age, 61.08 years) and 73 healthy subjects (mean age, 58.96 years). The whole brain was parcellated into 95 regions of interest using composite anatomical atlases, and region volumes were calculated. Three diagnostic classifiers were constructed using binary multiple logistic regression modeling: the (i) basal ganglion prior classifier, (ii) data-driven classifier, and (iii) basal ganglion prior/data-driven hybrid classifier. Leave-one-out cross validation was used to unbiasedly evaluate the predictive accuracy of imaging features. Pearson's correlation analysis was further performed to correlate outcome measurement using the best PD classifier with disease severity. Smaller volume in susceptible regions is diagnostic for Parkinson's disease. Compared with the other two classifiers, the basal ganglion prior/data-driven hybrid classifier had the highest diagnostic reliability with a sensitivity of 74%, specificity of 75%, and accuracy of 74%. Furthermore, outcome measurement using this classifier was associated with disease severity. Brain structural volumetric analysis with multiple logistic regression modeling can be a complementary tool for diagnosing PD. (orig.)

  3. Plasma Channel Diagnostic Based on Laser Centroid Oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Gonsalves, Anthony; Nakamura, Kei; Lin, Chen; Osterhoff, Jens; Shiraishi, Satomi; Schroeder, Carl; Geddes, Cameron; Toth, Csaba; Esarey, Eric; Leemans, Wim

    2010-09-09

    A technique has been developed for measuring the properties of discharge-based plasma channels by monitoring the centroid location of a laser beam exiting the channel as a function of input alignment offset between the laser and the channel. The centroid position of low-intensity (<10{sup 14}Wcm{sup -2}) laser pulses focused at the input of a hydrogen-filled capillary discharge waveguide was scanned and the exit positions recorded to determine the channel shape and depth with an accuracy of a few %. In addition, accurate alignment of the laser beam through the plasma channel can be provided by minimizing laser centroid motion at the channel exit as the channel depth is scanned either by scanning the plasma density or the discharge timing. The improvement in alignment accuracy provided by this technique will be crucial for minimizing electron beam pointing errors in laser plasma accelerators.

  4. Diagnostics of atmospheric pressure capillary DBD oxygen plasma jet

    CERN Document Server

    Roy, N C; Pramanik, B K

    2015-01-01

    Atmospheric pressure capillary dielectric barrier oxygen discharge plasma jet is developed to generate non-thermal plasma using unipolar positive pulse power supply. Both optical and electrical techniques are used to investigate the characteristics of the produced plasma as function of applied voltage and gas flow rate. Analytical results obtained from the optical emission spectroscopic data reveal the gas temperature, rotational temperature, excitation temperature and electron density. Gas temperature and rotational temperature are found to decrease with increasing oxygen flow rate but increase linearly with applied voltage. It is exposed that the electron density is boosting up with enhanced applied voltage and oxygen flow rate, while the electron excitation temperature is reducing with rising oxygen flow rate. Electrical characterization demonstrates that the discharge frequency is falling with flow rate but increasing with voltage. The produced plasma is applied preliminarily to study the inactivation yie...

  5. Imaging Charged Dust in Laboratory Plasmas

    Science.gov (United States)

    Goree, John

    2010-05-01

    Laboratory experiments with dust grains are described in this talk, which will include numerous images and videos from the experiments. In all the experiments, grains are immersed in plasma, and they are electrically charged. In the first experiment, grains are synthesized under conditions that simulate the outflow of carbon stars. These grains are grown in the gas phase with a carbon vapor. They grow by homogeneous nucleation, accretion, and coagulation. After growth, they are collected and imaged by scanning electron microscopy. These images reveal the grain morphology. In the second experiment, the structure and dynamics of the liquid or solid-phase centers of a star is simulated in the laboratory using charged grains (precision micron-size spheres) as proxies for protons. These grains are imaged by video microscopy, revealing how they self-organize, arranging themselves spatially in a crystalline-like lattice due to mutual Coulomb repulsion. Video microscopy allows tracking the motion of the microspheres and calculating their velocities. This measurement allows the experimenter to detect waves corresponding to random thermal motion, and from the properties of these waves one can measure the grain's charge. In the third experiment, sound waves in a cloud of charged dust are observed using high-speed video cameras. The compression and rarefaction of the dust-grain number density are easily observed in the video. Work supported by NSF and NASA.

  6. Dose and diagnostic image quality in digital tomosynthesis imaging of facial bones in pediatrics

    Science.gov (United States)

    King, J. M.; Hickling, S.; Elbakri, I. A.; Reed, M.; Wrogemann, J.

    2011-03-01

    The purpose of this study was to evaluate the use of digital tomosynthesis (DT) for pediatric facial bone imaging. We compared the eye lens dose and diagnostic image quality of DT facial bone exams relative to digital radiography (DR) and computed tomography (CT), and investigated whether we could modify our current DT imaging protocol to reduce patient dose while maintaining sufficient diagnostic image quality. We measured the dose to the eye lens for all three modalities using high-sensitivity thermoluminescent dosimeters (TLDs) and an anthropomorphic skull phantom. To assess the diagnostic image quality of DT compared to the corresponding DR and CT images, we performed an observer study where the visibility of anatomical structures in the DT phantom images were rated on a four-point scale. We then acquired DT images at lower doses and had radiologists indicate whether the visibility of each structure was adequate for diagnostic purposes. For typical facial bone exams, we measured eye lens doses of 0.1-0.4 mGy for DR, 0.3-3.7 mGy for DT, and 26 mGy for CT. In general, facial bone structures were visualized better with DT then DR, and the majority of structures were visualized well enough to avoid the need for CT. DT imaging provides high quality diagnostic images of the facial bones while delivering significantly lower doses to the lens of the eye compared to CT. In addition, we found that by adjusting the imaging parameters, the DT effective dose can be reduced by up to 50% while maintaining sufficient image quality.

  7. Developing an edge-plasma diagnostic tool for the Globus-M tokamak based on measuring ratios of HeI lines

    Science.gov (United States)

    Timokhin, V. M.; Rykachevskii, A. I.; Miroshnikov, I. V.; Sergeev, V. Yu.; Kochergin, M. M.; Koval', A. N.; Mukhin, E. E.; Tolstyakov, S. Yu.; Voronin, A. V.

    2016-08-01

    A diagnostic technique that is based on measuring the ratios of neutral-helium line strengths has been developed for peripheral distributions of electron temperature and density of tokamak plasma. The main components of the technique are a four-channel filter-lens imaging polychromator (FLIP-4) and a Phantom Miro M110 high-speed camera for recording the images. The polychromator has been assembled, adjusted, and tested on an optical test bench. The optical system was installed on the spherical Globus-M tokamak. Some preliminary experiments were carried out. Images of the plasma-gun jet were obtained at neutralhelium lines.

  8. ECE diagnostic of high temperature ECRH heated plasmas on FTU

    Energy Technology Data Exchange (ETDEWEB)

    Zerbini, M; Buratti, P; Tudisco, O; Giruzzi, G; Bruschi, A; Cirant, S; Granucci, G; Simonetto, A; Sozzi, C; Gandini, F; Pacella, D; Fournier, K B; Finkenthal, M

    2000-01-31

    The Electron Cyclotron Emission (ECE) diagnostic on FTU tokamak is routinely performed with a Michelson interferometer with spectral range extending up to 1300 GHz. The diagnostic allowed accurate electron temperature measurements during the recent 140 Ghz Electron Cyclotron Resonance Heating (ECRH) experiments on FTU. Very accurate measurements have been performed on a wide range of electron temperatures and profile peaking. The ECE measurements have been compared with Thomson Scattering and with observations of X-ray spectra from highly stripped molybdenum ions. The suprathermal emission in these conditions has been studied.

  9. Laser-induced incandescence diagnostic for in situ monitoring of nanoparticle synthesis in an atmospheric plasma

    Science.gov (United States)

    Mitrani, James; Patel, Shane; Shneider, Mikhail; Stratton, Brent; Raitses, Yevgeny

    2014-10-01

    A DC arc discharge with a consumed graphite electrode is commonly used for synthesis of carbon nanoaparticles in a low temperature (0.1-1 eV), atmospheric pressure plasma. The formation of nanoparticles in this plasma is poorly understood; it is not clear where nanoparticles nucleate and grow in the arc discharge. Therefore, a laser-induced incandescence (LII) diagnostic for in situ monitoring of the nanoparticles' spatial distribution in the plasma is currently being constructed. The LII diagnostic involves heating the particles with a short-pulsed laser, and measuring the induced spatiotemporal incandescence profiles on longer timescales. By appropriately modeling the induced spatiotemporal incandescence profiles, one can measure particle diameters and volume fraction. LII diagnostics have been extensively used to study soot particles in flames. However, they have never been applied in a strongly coupled plasma background. Even though the spatial dimensions for soot and nanoparticles are similar, great care is needed in developing an LII diagnostic for monitoring nanoparticles in a plasma background. Therefore, we will calibrate our LII diagnostic by measuring spatiotemporal incandescence profiles of known, research grade soot and nanoparticles. This work was supported by DOE Contract DE-AC02-09CH11466.

  10. Novel plasma and imaging biomarkers in heart failure with preserved ejection fraction

    Directory of Open Access Journals (Sweden)

    Prathap Kanagala

    2015-12-01

    Full Text Available Existing diagnostic guidelines for heart failure with preserved ejection fraction (HFPEF primarily comprise natriuretic peptides and echocardiographic assessment, highlighting the role of diastolic dysfunction. However, recent discoveries of novel plasma markers implicated in pathophysiology of heart failure and technological advances in imaging provide additional biomarkers which are potentially applicable to HFPEF. The evidence base for plasma extra-cellular matrix (ECM peptides, galectin-3, ST2, GDF-15 and pentraxin-3 is reviewed. Furthermore, the capabilities of novel imaging techniques to assess existing parameters (e.g. left ventricular ejection fraction, systolic & diastolic function, chamber size and additional derangements of the ECM, myocardial mechanics and ischaemia evaluation are addressed.

  11. Strategic planning for radiology: opening an outpatient diagnostic imaging center.

    Science.gov (United States)

    Leepson, Evan

    2003-01-01

    Launching a new diagnostic imaging center involves very specific requirements and roadmaps, including five major areas of change that have a direct impact on planning: Imaging and communication technology Finances and reimbursement Ownership structure of imaging entities Critical workforce shortages Imaging is moving outside radiology First, planning must focus on the strategic level of any organization, whether it is a multi-national corporation or a six-person radiology group. Think of all organizations as a triangle with three horizontal levels: strategic, managerial and operational. The strategic level of decision-making is at the top of the triangle, and here is where planning must take place. For strategic planning to work, there must be focused time and energy spent on this activity, usually away from the reading room and imaging center. There are five planning strategies, which must have the explicit goal of developing and growing the imaging center. The five strategies are: Clinical and quality issues, Governance and administration, Technology, Relationships, Marketing and business development. The best way to plan and implement these strategies is to create work groups of radiologists, technologists, and administrative and support staff. Once the group agrees on the strategy and tactic, it takes responsibility for implementation. Embarking on the launch of a new outpatient diagnostic imaging center is no small undertaking, and anyone who has struggled with such an endeavor can readily attest to the associated challenges and benefits. Success depends on many things, and one of the most important factors relates to the amount of time and the quality of effort spent on strategic planning at the outset. Neglecting or skimping on this phase may lead to unforeseen obstacles that could potentially derail the project.

  12. Diagnostics for plasma control on DEMO: challenges of implementation

    NARCIS (Netherlands)

    Donne, A. J. H.; Costley, A. E.; Morris, A. W.

    2012-01-01

    As a test fusion power plant, DEMO will have to demonstrate reliability and very long pulse/steady-state operation, which calls for unprecedented robustness and reliability of all diagnostic systems (also requiring adequate redundancy). But DEMO will have higher levels of neutron and gamma fluxes, a

  13. Diagnostics for plasma control on DEMO: challenges of implementation

    NARCIS (Netherlands)

    Donne, A. J. H.; Costley, A. E.; Morris, A. W.

    2012-01-01

    As a test fusion power plant, DEMO will have to demonstrate reliability and very long pulse/steady-state operation, which calls for unprecedented robustness and reliability of all diagnostic systems (also requiring adequate redundancy). But DEMO will have higher levels of neutron and gamma fluxes,

  14. Development of local oscillator integrated antenna array for microwave imaging diagnostics

    Science.gov (United States)

    Kuwahara, D.; Ito, N.; Nagayama, Y.; Tsuchiya, H.; Yoshikawa, M.; Kohagura, J.; Yoshinaga, T.; Yamaguchi, S.; Kogi, Y.; Mase, A.; Shinohara, S.

    2015-12-01

    Microwave imaging diagnostics are powerful tools that are used to obtain details of complex structures and behaviors of such systems as magnetically confined plasmas. For example, microwave imaging reflectometry and microwave imaging interferometers are suitable for observing phenomena that are involved with electron density fluctuations; moreover, electron cyclotron emission imaging diagnostics enable us to accomplish the significant task of observing MHD instabilities in large tokamaks. However, microwave imaging systems include difficulties in terms of multi-channelization and cost. Recently, we solved these problems by developing a Horn-antenna Mixer Array (HMA), a 50 - 110 GHz 1-D heterodyne- type antenna array, which can be easily stacked as a 2-D receiving array, because it uses an end-fire element. However, the HMA still evidenced problems owing to the requirement for local oscillation (LO) optics and an expensive high-power LO source. To solve this problem, we have developed an upgraded HMA, named the Local Integrated Antenna array (LIA), in which each channel has an internal LO supply using a frequency multiplier integrated circuit. Therefore, the proposed antenna array eliminates the need for both the LO optics and the high-power LO source. This paper describes the principle of the LIA, and provides details about an 8 channel prototype LIA.

  15. Plasma cell gingivitis associated with cheilitis: A diagnostic dilemma!

    Directory of Open Access Journals (Sweden)

    Presanthila Janam

    2012-01-01

    Full Text Available Plasma cell gingivitis is a rare condition characterized by diffuse and massive infiltration of plasma cells into the sub-epithelial connective tissue. Clinically, it appears as a diffuse reddening and edematous swelling of the gingiva with a sharp demarcation along the mucogingival border. Though considered as a hypersensitive reaction to an allergen, the etiology of this bizarre condition is still not properly understood. Here, we present an interesting case of plasma cell gingivitis associated with an enlarged and fissured upper lip, which is quite a rarity. The condition was diagnosed based on clinical and histopathologic findings and treated by gingivectomy. The associated cheilitis has dramatically reduced after treatment of the gingival lesion.

  16. Diagnostic studies of ion beam formation in inductively coupled plasma

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, Jenee L. [Iowa State Univ., Ames, IA (United States)

    2015-01-01

    This dissertation describes a variety of studies focused on the plasma and the ion beam in inductively coupled plasma mass spectrometry (ICP-MS). The ability to use ICP-MS for measurements of trace elements in samples requires the analytes to be efficiently ionized. Updated ionization efficiency tables are discussed for ionization temperatures of 6500 K and 7000 K with an electron density of 1 x 1015 cm-3. These values are reflective of the current operating parameters of ICP-MS instruments. Calculations are also discussed for doubly charged (M2+) ion formation, neutral metal oxide (MO) ionization, and metal oxide (MO+) ion dissociation for similar plasma temperature values. Ionization efficiency results for neutral MO molecules in the ICP have not been reported previously.

  17. The diagnostic accuracy of MR imaging in osteoid osteoma

    Energy Technology Data Exchange (ETDEWEB)

    Davies, Mark; Cassar-Pullicino, Victor N.; McCall, Iain W.; Tyrrell, Prudencia N.M. [Department of Radiology, The Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, Shropshire, SY10 7AG (United Kingdom); Davies, Mark A. [The MRI Centre, Royal Orthopaedic Hospital, Birmingham (United Kingdom)

    2002-10-01

    To analyse the MR imaging appearances of a large series of osteoid osteomas, to assess the ability of MR imaging to detect the tumour, and to identify potential reasons for misdiagnosis.Design and patients. The MR imaging findings of 43 patients with osteoid osteoma were reviewed retrospectively and then compared with other imaging modalities to assess the accuracy of MR localisation and interpretation.Results. The potential for a missed diagnosis was 35% based solely on the MR investigations. This included six tumours which were not seen and nine which were poorly visualised. The major determinants of the diagnostic accuracy of MR imaging were the MR technique, skeletal location, and preliminary radiographic appearances. There was a wide spectrum of MR signal appearances of the lesion. The tumour was identified in 65% of sequences performed in the axial plane. The nidus was present in only one slice of the optimal sequence in 27 patients. Reactive bone changes were present in 33 and soft tissue changes in 37 patients.Conclusion. Reliance on MR imaging alone may lead to misdiagnosis. As the osteoid osteoma may be difficult to identify and the MR features easily misinterpreted, optimisation of MR technique is crucial in reducing the risk of missing the diagnosis. Unexplained areas of bone marrow oedema in particular require further imaging (scintigraphy and CT) to exclude an osteoid osteoma. (orig.)

  18. Microwave cavity diagnostics of microwave breakdown plasmas. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Eckstrom, D.J.; Williams, M.S. [SRI International, Menlo Park, CA (United States)

    1989-08-01

    We have performed microwave cavity perturbation measurements in the LLNL AIM facility using a 329-MHz cavity that allow us to examine in detail the plasma formation and decay processes for electron densities between approximately 10{sup 5} and 10{sup 7}/cm{sup 3}. We believe these to be the lowest density plasmas ever studied in microwave breakdown experiments, and as such they allow us to determine the power and energy required to produce plasmas suitable for HF radar reflection as well as the effective lifetimes of these plasmas before re-ionization is required. Analyses of these results leads to the following conclusions. (1) For microwave breakdown pulses varying from 0.6 to 2.4 {mu}s, the threshold power required to produce measurable plasmas is 30 to 12 MW/m{sup 2} at 0.01 torr, decreasing to 3.5 to 1.8 MW/m{sup 2} at 1 to 3 torr, and then increasing to 5 to 3.5 MW/m{sup 2} at 30 torr. The threshold power in each case decreases with increasing pulse length, but the required pulse energy increases with decreasing power or increasing pulse length. (2) The effective electron density decay rates are approximately 100/s for 0.1 to 1 torr, after which they increase linearly with pressure. Thus, the useful plasma lifetimes are in the range of 20 to 40 ms at the lower pressures and decrease to about 1 ms at 30 torr. These decay rates and lifetimes are comparable to those that would exist for artificially ionized regions in the upper atmosphere. (3) The collision frequencies measured at pressures of 1 torr and above correspond to electron temperatures of 800 K or less. In fact, the inferred temperatures for p > 3 torr are below room temperature. This may be due to a contribution to the measured conductivity by negative ions.

  19. Plasma diagnostics during magnetron sputtering of aluminum doped zinc oxide

    DEFF Research Database (Denmark)

    Stamate, Eugen; Crovetto, Andrea; Sanna, Simone

    2016-01-01

    Plasma parameters during magnetron sputtering of aluminum-doped zinc oxide are investigated with optical emission spectroscopy, electrostatic probes and mass spectrometry with the aim of understanding the role of negative ions of oxygen during the film growth and improving the uniformity of the f......Plasma parameters during magnetron sputtering of aluminum-doped zinc oxide are investigated with optical emission spectroscopy, electrostatic probes and mass spectrometry with the aim of understanding the role of negative ions of oxygen during the film growth and improving the uniformity...

  20. Plasma Diagnostic in laser ablation plumes for isotope separation applications

    Energy Technology Data Exchange (ETDEWEB)

    Matos, Juliana B. de [Instituto Tecnologico de Aeronautica, Sao Jose dos Campos, SP (Brazil)]. E-mail: juliana@ieav.cta.br; Rodrigues, Nicolau A.S.; Neri, Jose W.; Silveira, Carlos A.B. [Instituto de Estudos Avancados (IEAv/EFO), Sao Jose dos Campos, SP (Brazil). Div. de Fotonica

    2008-07-01

    The plasma plume produced in vacuum by ablation of copper, aluminum and tungsten samples, illuminated by copper laser pulses, was investigated. A Langmuir probe was used to study the macroscopic parameters electron number density (Ne) and electron temperature (Te). Plasma expansion velocity (Vp) was also investigated and it was studied the dependence of these parameters with the laser irradiance. Typical values are respectively N{sub e} {approx} 10{sup 8}-10{sup 9}/cm{sup 3}, T{sub e} {approx} 15 eV and Vp {approx} 10 km/s. (author)

  1. Accuracy of diagnostic imaging in nephroblastoma before preoperative chemotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Rieden, K. [Radiologische Klinik, Abt. Klinische Radiologie, Heidelberg (Germany); Weirich, A. [Kinderklinik, Univ. of Heidelberg (Germany); Troeger, J. [Radiologische Klinik, Abt. Paediatrische Radiologie, Univ. of Heidelberg (Germany); Gamroth, A.H. [Deutsches Krebsforschungszentrum, Heidelberg (Germany); Raschke, K. [Radiologische Klinik, Abt. Paediatrische Radiologie, Univ. of Heidelberg (Germany); Ludwig, R. [Kinderklinik, Univ. of Heidelberg (Germany)

    1993-04-01

    From July 1988 to February 1991, 130 children with the tentative diagnosis of nephroblastoma were treated preoperatively. The initial diagnostic images (excretory urography, ultrasound, CT, MRI) have been analysed both prospectively and retrospectively and the findings correlated with the intraoperative and histological results. Of the preoperatively treated patients 93.8% had a Wilms` tumour or one of its variants. Five patients had a different malignant tumour and 3 patients, i.e. 2.3% of those preoperatively treated or 1.6% of all registered patients, had benign tumours of the kidney. Wilms` tumour generally presented as a well-defined mass with an inhomogeneous morphology on CT. On ultrasound only 24% of the tumours were homogeneous. Intratumoral haemorrhage and cystic areas occurred frequently; calcifications were rare (8%). With regard to caval involvement only ultrasound and MRI enabled the correct diagnosis, while CT could not differentiate compressions from invasion. The pretherapeutic diagnostic imaging was of sufficient accuracy to start preoperative chemotherapy without diagnostic biopsy. (orig.)

  2. Application of aptamers in diagnostics, drug-delivery and imaging

    Indian Academy of Sciences (India)

    CHETAN CHANDOLA; SHEETAL KALME; MARCO G CASTELEIJN; ARTO URTTI; MUNIASAMY NEERATHILINGAM

    2016-09-01

    Aptamers are small, single-stranded oligonucleotides (DNA or RNA) that bind to their target with high specificity andaffinity. Although aptamers are analogous to antibodies for a wide range of target recognition and variety ofapplications, they have significant advantages over antibodies. Since aptamers have recently emerged as a class ofbiomolecules with an application in a wide array of fields, we need to summarize the latest developments herein. Inthis review we will discuss about the latest developments in using aptamers in diagnostics, drug delivery and imaging.We begin with diagnostics, discussing the application of aptamers for the detection of infective agents itself, antigens/toxins (bacteria), biomarkers (cancer), or a combination. The ease of conjugation and labelling of aptamers makesthem a potential tool for diagnostics. Also, due to the reduced off-target effects of aptamers, their use as a potentialdrug delivery tool is emerging rapidly. Hence, we discuss their use in targeted delivery in conjugation with siRNAs,nanoparticles, liposomes, drugs and antibodies. Finally, we discuss about the conjugation strategies applicable forRNA and DNA aptamers for imaging. Their stability and self-assembly after heating makes them superior overprotein-based binding molecules in terms of labelling and conjugation strategies.

  3. Choice of diagnostic and therapeutic imaging in periodontics and implantology.

    Science.gov (United States)

    Chakrapani, Swarna; Sirisha, K; Srilalitha, Anumadi; Srinivas, Moogala

    2013-11-01

    Imaging forms an integral component for diagnosis of dental and in specific periodontal diseases. To date, intra-oral radiographic techniques are the main non-invasive diagnostic aids for the detection and assessment of internal changes in mineralized periodontal tissues like alveolar bone. These analog radiographic techniques suffer from inherent limitations like: Two dimensional projection, magnification, distortion, superimposition and misrepresentation of anatomic structures. The evolution of novel imaging modalities, namely cone beam computed tomography, tuned aperture CT empowered dental researchers to visualize the periodontium three dimensionally. This improves interpretation of structural and biophysical changes, ensures densitometric assessments of dentoalveolar structures including variations in alveolar bone density, and peri-implant bone healing more precisely. This detailed review, highlights current leading edge concepts, envisions a wide range of imaging modalities which pave the way for better understanding and early intervention of periodontal diseases.

  4. Application of coherent lidar to ion measurements in plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Hutchinson, D.P.; Richards, R.K.; Bennett, C.A.; Simpson, M.L.

    1997-03-01

    A coherent lidar system has been constructed for the measurement of alpha particles in a burning plasma. The lidar system consists of a pulsed CO{sub 2} laser transmitter and a heterodyne receiver. The receiver local oscillator is a cw, sequence-band CO{sub 2} laser operating with a 63.23 GHz offset from the transmitter.

  5. Overview of C-2 field-reversed configuration experiment plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Gota, H., E-mail: hgota@trialphaenergy.com; Thompson, M. C.; Tuszewski, M.; Binderbauer, M. W. [Tri Alpha Energy, Inc., Rancho Santa Margarita, California 92688 (United States)

    2014-11-15

    A comprehensive diagnostic suite for field-reversed configuration (FRC) plasmas has been developed and installed on the C-2 device at Tri Alpha Energy to investigate the dynamics of FRC formation as well as to understand key FRC physics properties, e.g., confinement and stability, throughout a discharge. C-2 is a unique, large compact-toroid merging device that produces FRC plasmas partially sustained for up to ∼5 ms by neutral-beam (NB) injection and end-on plasma-guns for stability control. Fundamental C-2 FRC properties are diagnosed by magnetics, interferometry, Thomson scattering, spectroscopy, bolometry, reflectometry, and NB-related fast-ion/neutral diagnostics. These diagnostics (totaling >50 systems) are essential to support the primary goal of developing a deep understanding of NB-driven FRCs.

  6. Overview of C-2 field-reversed configuration experiment plasma diagnostics.

    Science.gov (United States)

    Gota, H; Thompson, M C; Tuszewski, M; Binderbauer, M W

    2014-11-01

    A comprehensive diagnostic suite for field-reversed configuration (FRC) plasmas has been developed and installed on the C-2 device at Tri Alpha Energy to investigate the dynamics of FRC formation as well as to understand key FRC physics properties, e.g., confinement and stability, throughout a discharge. C-2 is a unique, large compact-toroid merging device that produces FRC plasmas partially sustained for up to ∼5 ms by neutral-beam (NB) injection and end-on plasma-guns for stability control. Fundamental C-2 FRC properties are diagnosed by magnetics, interferometry, Thomson scattering, spectroscopy, bolometry, reflectometry, and NB-related fast-ion/neutral diagnostics. These diagnostics (totaling >50 systems) are essential to support the primary goal of developing a deep understanding of NB-driven FRCs.

  7. Physical therapist practice and the role of diagnostic imaging.

    Science.gov (United States)

    Boyles, Robert E; Gorman, Ira; Pinto, Daniel; Ross, Michael D

    2011-11-01

    For healthcare providers involved in the management of patients with musculoskeletal disorders, the ability to order diagnostic imaging is a beneficial adjunct to screening for medical referral and differential diagnosis. A trial of conservative treatment, such as physical therapy, is often recommended prior to the use of imaging in many treatment guidelines for the management of musculoskeletal conditions. In the United States, physical therapists are becoming more autonomous and can practice some degree of direct access in 48 states and Washington, DC. Referral for imaging privileges could increase the effectiveness and efficiency of healthcare delivery, particularly in combination with direct access management. This clinical commentary proposes that, given the American Physical Therapy Association's goal to have physical therapists as primary care musculoskeletal specialists of choice, it would be beneficial for physical therapists to have imaging privileges in their practice. The purpose of this commentary is 3-fold: (1) to make a case for the use of imaging privileges by physical therapists, using a historical perspective; (2) to discuss the barriers preventing physical therapists from having this privilege; and (3) to offer suggestions on strategies and guidelines to facilitate the appropriate inclusion of referral for imaging privileges in physical therapist practice. J Orthop Sports Phys Ther 2011;41(11):829-837. doi:10.2519/jospt.2011.3556.

  8. Perspective: The physics, diagnostics, and applications of atmospheric pressure low temperature plasma sources used in plasma medicine

    Science.gov (United States)

    Laroussi, M.; Lu, X.; Keidar, M.

    2017-07-01

    Low temperature plasmas have been used in various plasma processing applications for several decades. But it is only in the last thirty years or so that sources generating such plasmas at atmospheric pressure in reliable and stable ways have become more prevalent. First, in the late 1980s, the dielectric barrier discharge was used to generate relatively large volume diffuse plasmas at atmospheric pressure. Then, in the early 2000s, plasma jets that can launch cold plasma plumes in ambient air were developed. Extensive experimental and modeling work was carried out on both methods and much of the physics governing such sources was elucidated. Starting in the mid-1990s, low temperature plasma discharges have been used as sources of chemically reactive species that can be transported to interact with biological media, cells, and tissues and induce impactful biological effects. However, many of the biochemical pathways whereby plasma affects cells remain not well understood. This situation is changing rather quickly because the field, known today as "plasma medicine," has experienced exponential growth in the last few years thanks to a global research community that engaged in fundamental and applied research involving the use of cold plasma for the inactivation of bacteria, dental applications, wound healing, and the destruction of cancer cells/tumors. In this perspective, the authors first review the physics as well as the diagnostics of the principal plasma sources used in plasma medicine. Then, brief descriptions of their biomedical applications are presented. To conclude, the authors' personal assessment of the present status and future outlook of the field is given.

  9. Laser Diagnostic Method for Plasma Sheath Potential Mapping

    Science.gov (United States)

    Walsh, Sean P.

    Electric propulsion systems are gaining popularity in the aerospace field as a viable option for long term positioning and thrusting applications. In particular, Hall thrusters have shown promise as the primary propulsion engine for space probes during interplanetary journeys. However, the interaction between propellant xenon ions and the ceramic channel wall continues to remain a complex issue. The most significant source of power loss in Hall thrusters is due to electron and ion currents through the sheath to the channel wall. A sheath is a region of high electric field that separates a plasma from a wall or surface in contact. Plasma electrons with enough energy to penetrate the sheath may result emission of a secondary electron from the wall. With significant secondary electron emission (SEE), the sheath voltage is reduced and so too is the electron retarding electric field. Therefore, a lower sheath voltage further increases the particle loss to the wall of a Hall thruster and leads to plasma cooling and lower efficiency. To further understand sheath dynamics, laser-induced fluorescence is employed to provide a non-invasive, in situ, and spatially resolved technique for measuring xenon ion velocity. By scanning the laser wavelength over an electronic transition of singly ionized xenon and collecting the resulting fluorescence, one can determine the ion velocity from the Doppler shifted absorption. Knowing the velocity at multiple points in the sheath, it can be converted to a relative electric potential profile which can reveal a lot about the plasma-wall interaction and the severity of SEE. The challenge of adequately measuring sheath potential profiles is optimizing the experiment to maximize the signal-to-noise ratio. A strong signal with low noise, enables high resolution measurements and increases the depth of measurement in the sheath, where the signal strength is lowest. Many improvements were made to reduce the background luminosity, increase the

  10. CT imaging in acute pulmonary embolism: diagnostic strategies

    Energy Technology Data Exchange (ETDEWEB)

    Wildberger, Joachim E.; Mahnken, Andreas H.; Das, Marco; Guenther, Rolf W. [University of Technology (RWTH), Department of Diagnostic Radiology, University Hospital, Aachen (Germany); Kuettner, Axel [Eberhard Karls University, Department of Diagnostic Radiology, Tuebingen (Germany); Lell, Michael [Friedrich Alexander University, Department of Diagnostic Radiology, Erlangen (Germany)

    2005-05-01

    Computed tomography pulmonary angiography (CTA) has increasingly become accepted as a widely available, safe, cost-effective, and accurate method for a quick and comprehensive diagnosis of acute pulmonary embolism (PE). Pulmonary catheter angiography is still considered the gold standard and final imaging method in many diagnostic algorithms. However, spiral CTA has become established as the first imaging test in clinical routine due to its high negative predictive value for clinically relevant PE. Despite the direct visualization of clot material, depiction of cardiac and pulmonary function in combination with the quantification of pulmonary obstruction helps to grade the severity of PE for further risk stratification and to monitor the effect of thrombolytic therapy. Because PE and deep venous thrombosis are two different aspects of the same disease, additional indirect CT venography may be a valuable addition to the initial diagnostic algorithm - if this was positive for PE - and demonstration of the extent and localization of deep venous thrombosis has an impact on clinical management. Additional and alternate diagnoses add to the usefulness of this method. Using advanced multislice spiral CT technology, some practitioners have advocated CTA as the sole imaging tool for routine clinical assessment in suspected acute PE. This will simplify standards of practice in the near future. (orig.)

  11. Australian per caput dose from diagnostic imaging and nuclear medicine.

    Science.gov (United States)

    Hayton, A; Wallace, A; Marks, P; Edmonds, K; Tingey, D; Johnston, P

    2013-10-01

    The largest man-made contributor to the ionising radiation dose to the Australian population is from diagnostic imaging and nuclear medicine. The last estimation of this dose was made in 2004 (1.3 mSv), this paper describes a recent re-evaluation of this dose to reflect the changes in imaging trends and technology. The estimation was calculated by summing the dose from five modalities, computed tomography (CT), general radiography/fluoroscopy, interventional procedures, mammography and nuclear medicine. Estimates were made using Australian frequency data and dose data from a range of Australian and international sources of average effective dose values. The ionising radiation dose to the Australian population in 2010 from diagnostic imaging and nuclear medicine is estimated to be 1.7 mSv (1.11 mSv CT, 0.30 mSv general radiography/fluoroscopy, 0.17 mSv interventional procedures, 0.03 mSv mammography and 0.10 mSv nuclear medicine). This exceeds the estimate of 1.5 mSv per person from natural background and cosmic radiation.

  12. Diagnostic imaging, a "parallel" discipline. Can current technology provide a reliable digital diagnostic radiology department?

    Science.gov (United States)

    Moore, C J; Eddleston, B

    1985-04-01

    Only recently has any detailed criticism been voiced about the practicalities of the introduction of generalised, digital, imaging complexes in diagnostic radiology. Although attendant technological problems are highlighted we argue that the fundamental causes of current difficulties are not in the generation but in the processing, filing and subsequent retrieval for display of digital image records. In the real world, looking at images is a parallel process of some complexity and so it is perhaps untimely to expect versatile handling of vast image data bases by existing computer hardware and software which, by their current nature, perform tasks serially. Successes in applying new imaging devices using digital technology, numerical methods and more easily available computing power are directing radiology towards the concept of all-digital departmental complexes. Hence a critical discussion of fundamental problems should be encouraged, to promote a thorough understanding of what may be involved (Gray et al, 1984) in following such a course. It is equally important to gain some perspective about the development possibilities for existing, commercially available equipment being offered to the medical community.

  13. In situ electromagnetic field diagnostics with an electron plasma in a Penning-Malmberg trap

    Science.gov (United States)

    Amole, C.; Ashkezari, M. D.; Baquero-Ruiz, M.; Bertsche, W.; Butler, E.; Capra, A.; Cesar, C. L.; Charlton, M.; Deller, A.; Evetts, N.; Eriksson, S.; Fajans, J.; Friesen, T.; Fujiwara, M. C.; Gill, D. R.; Gutierrez, A.; Hangst, J. S.; Hardy, W. N.; Hayden, M. E.; Isaac, C. A.; Jonsell, S.; Kurchaninov, L.; Little, A.; Madsen, N.; McKenna, J. T. K.; Menary, S.; Napoli, S. C.; Olchanski, K.; Olin, A.; Pusa, P.; Rasmussen, C. Ø.; Robicheaux, F.; Sarid, E.; Silveira, D. M.; So, C.; Stracka, S.; Tharp, T.; Thompson, R. I.; van der Werf, D. P.; Wurtele, J. S.

    2014-01-01

    We demonstrate a novel detection method for the cyclotron resonance frequency of an electron plasma in a Penning-Malmberg trap. With this technique, the electron plasma is used as an in situ diagnostic tool for the measurement of the static magnetic field and the microwave electric field in the trap. The cyclotron motion of the electron plasma is excited by microwave radiation and the temperature change of the plasma is measured non-destructively by monitoring the plasma's quadrupole mode frequency. The spatially resolved microwave electric field strength can be inferred from the plasma temperature change and the magnetic field is found through the cyclotron resonance frequency. These measurements were used extensively in the recently reported demonstration of resonant quantum interactions with antihydrogen.

  14. Laser Thomson scattering diagnostics of non-equilibrium high pressure plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Muraoka, K.; Uchino, K.; Bowden, M.D.; Noguchi, Y. [Kyushu Univ., Fukuoka (Japan). Interdisciplinary Graduate School of Engineering Sciences

    2001-07-01

    For various applications of non-equilibrium high pressure plasmas, knowledge of electron properties, such as electron density, electron temperature and/or electron energy distribution function (eedf), is prerequisite for any rational approach to understanding physical and chemical processes occurring in the plasmas. For this purpose, laser Thomson scattering has been successfully applied for the first time to measure the electron properties in plasmas for excimer laser pumping and in microdischarges. Although this diagnostic technique is well established for measurements in high temperature plasmas, its applications to these glow discharge plasmas have had various inherent difficulties, such as a presence of high density neutral particles (>10{sup 21} m{sup -3}) in the excimer laser pumping discharges and an extremely small plasma size (<0.1 mm) and the presence of nearby walls for microdischarges. These difficulties have been overcome and clear signals have been obtained. The measured results are presented and their implications in the respective discharge phenomena are discussed.

  15. In situ electromagnetic field diagnostics with an electron plasma in a Penning-Malmberg trap

    CERN Document Server

    Amole, C; Baquero-Ruiz, M.; Bertsche, W.; Butler, E.; Capra, A.; Cesar, C.L.; Charlton, M.; Deller, A.; Evetts, N.; Eriksson, S.; Fajans, J.; Friesen, T.; Fujiwara, M.C.; Gill, D.R.; Gutierrez, A.; Hangst, J.S.; Hardy, W.N.; Hayden, M.E.; Isaac, C.A.; Jonsell, S.; Kurchaninov, L.; Little, A.; Madsen, N.; McKenna, J.T.K.; Menary, S.; Napoli, S.C.; Olchanski, K.; Olin, A.; Pusa, P.; Rasmussen, C.; Robicheaux, F.; Sarid, E.; Silveira, D.M.; So, C.; Stracka, S.; Tharp, T.; Thompson, R.I.; van der Werf, D.P.; Wurtele, J.S.

    2014-01-01

    We demonstrate a novel detection method for the cyclotron resonance frequency of an electron plasma in a Penning-Malmberg trap. With this technique, the electron plasma is used as an in situ diagnostic tool for measurement of the static magnetic field and the microwave electric field in the trap. The cyclotron motion of the electron plasma is excited by microwave radiation and the temperature change of the plasma is measured non-destructively by monitoring the plasma's quadrupole mode frequency. The spatially-resolved microwave electric field strength can be inferred from the plasma temperature change and the magnetic field is found through the cyclotron resonance frequency. These measurements were used extensively in the recently reported demonstration of resonant quantum interactions with antihydrogen.

  16. Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Weinstock-Guttmann Bianca

    2010-10-01

    Full Text Available Abstract Background This study compared the level of advanced glycation end products (AGEs, N-(Carboxymethyllysine (CML and N-(Carboxyethyllysine (CEL, in patients with multiple sclerosis (MS and healthy controls (HCs, correlating these markers with clinical indicators of MS disease severity. Methods CML and CEL plasma levels were analyzed in 99 MS patients and 43 HCs by tandem mass spectrometry (LC/MS/MS. Patients were stratified based on drug modifying therapies (DMTs including interferon beta, glatiramer acetate and natalizumab. Results The level of plasma CEL, but not CML, was significantly higher in DMT-naïve MS patients when compared to HCs (P Conclusion Our results suggest that AGEs in general and CEL in particular could be useful biomarkers in MS clinical practice. Longitudinal studies are warranted to determine any causal relationship between changes in plasma level of AGEs and MS disease pathology. These studies will pave the way for use of AGE inhibitors and AGE-breaking agents as new therapeutic modalities in MS.

  17. [Positron emission tomography: diagnostic imaging on a molecular level].

    Science.gov (United States)

    Allemann, K; Wyss, M; Wergin, M; Bley, C Rohrer; Ametamay, S; Bruehlmeier, M; Kaser-Hotz, B

    2004-08-01

    In human medicine positron emission tomography (PET) is a modern diagnostic imaging method. In the present paper we outline the physical principles of PET and give an overview over the main clinic fields where PET is being used, such as neurology, cardiology and oncology. Moreover, we present a current project in veterinary medicine (in collaboration with the Paul Scherrer Institute and the University Hospital Zurich), where a hypoxia tracer is applied to dogs and cats suffering from spontaneous tumors. Finally new developments in the field of PET were discussed.

  18. Plasma tests of diagnostic mirrors for ITER purposes

    Energy Technology Data Exchange (ETDEWEB)

    Vukolov, K.Yu., E-mail: vukolov@nfi.kiae.ru [NRC “Kurchatov Institute”, Kurchatov sq.1, 123182 Moscow (Russian Federation); Mukhammedzyanov, T.R.; Andreenko, E.N. [NRC “Kurchatov Institute”, Kurchatov sq.1, 123182 Moscow (Russian Federation); Arkhipov, I.I. [A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, RAS, Leninsky pr. 31, 119991 Moscow (Russian Federation); Orlovskiy, I.I.; Tobengauz, A.M.; Vukolov, D.K. [NRC “Kurchatov Institute”, Kurchatov sq.1, 123182 Moscow (Russian Federation)

    2013-10-15

    Highlights: •Prototype of ITER H-alpha endoscope with 1 mm pupil is tested in T-10 tokamak. •Three molybdenum mirrors either preserved their reflectivity or were locally damaged. •First mirror assembly with 4 mm pupil was tested in ITER-like conditions. •Mirrors preserved their reflectivity after 40 h test treated as 400 pulses. •Small entrance pupil is vital for lifetime of the first mirror. -- Abstract: One of the main problems of ITER optical diagnostics is the degradation of collecting mirrors by erosion or impurity deposition. It is suggested to reduce the degradation by small entrance pupil in optical system. The prototype of endoscope optical system for H-alpha ITER diagnostics is under testing in T-10 tokamak. It has entrance pupil of 1 mm diameter. Three molybdenum mirrors were tested between 1 and 3 years. In spite of local degradation or surface damages appeared after 2 years of operation, the diagnostics remained functional. In parallel, the first mirror assembly (FMA) with 4 mm pupil was tested in a magnetron sputtering installation. Deuterium pressure was 0.7 Pa during magnetron discharge with 1 A current. Estimated flux of aluminum and carbon atoms was about 10{sup 14} at cm{sup −2} s{sup −1} on the FMA entrance pupil. As a result, FMA molybdenum mirrors preserved their reflectivity after 40 h of exposure which can be considered as 400 ITER pulses. Thereby small entrance pupil appears as a good solution for first mirror protection.

  19. Nonlinear frequency shift in Raman backscattering and its implications for plasma diagnostics

    Science.gov (United States)

    Kaganovich, D.; Hafizi, B.; Palastro, J. P.; Ting, A.; Helle, M. H.; Chen, Y.-H.; Jones, T. G.; Gordon, D. F.

    2016-12-01

    Raman backscattered radiation of intense laser pulses in plasmas is investigated for a wide range of intensities relevant to laser wakefield acceleration. The weakly nonlinear dispersion relation for Raman backscattering predicts an intensity and density dependent frequency shift that is opposite to that suggested by a simple relativistic consideration. This observation has been benchmarked against experimental results, providing a novel diagnostic for laser-plasma interactions.

  20. Nonlinear Frequency Shift in Raman Backscattering and its Implications for Plasma Diagnostics

    CERN Document Server

    Kaganovich, D; Palastro, J P; Ting, A; Helle, M H; Chen, Y -H; Jones, T G; Gordon, D F

    2016-01-01

    Raman backscattered radiation of intense laser pulses in plasma is investigated for a wide range of intensities relevant to laser wakefield acceleration. The weakly nonlinear dispersion relation for Raman backscattering predicts an intensity and density dependent frequency shift that is opposite to that suggested by a simple relativistic consideration. This observation has been benchmarked against experimental results, providing a novel diagnostic for laser-plasma interactions.

  1. Plasma diagnostic techniques in thermal-barrier tandem-mirror fusion experiments

    Energy Technology Data Exchange (ETDEWEB)

    Silver, E.H.; Clauser, J.F.; Carter, M.R.; Failor, B.H.; Foote, J.H.; Hornady, R.S.; James, R.A.; Lasnier, C.J.; Perkins, D.E.

    1986-08-29

    We review two classes of plasma diagnostic techniques used in thermal-barrier tandem-mirror fusion experiments. The emphasis of the first class is to study mirror-trapped electrons at the thermal-barrier location. The focus of the second class is to measure the spatial and temporal behavior of the plasma space potential at various axial locations. The design and operation of the instruments in these two categories are discussed and data that are representative of their performance is presented.

  2. Diagnostics of Atmospheric Pressure Surface Discharge Plasmas in Argon

    Institute of Scientific and Technical Information of China (English)

    张锐; 詹如娟; 温晓辉

    2003-01-01

    Atmospheric pressure surface discharge is shown to have great prospects for a number of industrial applications.To acquire better results in application fields and considering that the study of the basic parameters including electron temperature and electron density is desirable,we develop an equivalent circuit model and the diagnostic techniques based on optical emission spectroscopy and electrical measurement in our laboratory.The electron temperature has been determined to be about 0.7eV by a Fermi-Dirac model.The electron density has been calculated to be near 1010 cm-3 from a time resolved electrical measurement(Ohmic heating method).

  3. Nonintrusive microwave diagnostics of collisional plasmas in Hall thrusters and dielectric barrier discharges

    Science.gov (United States)

    Stults, Joshua

    This research presents a numerical framework for diagnosing electron properties in collisional plasmas. Microwave diagnostics achieved a significant level of development during the middle part of the last century due to work in nuclear weapons and fusion plasma research. With the growing use of plasma-based devices in fields as diverse as space propulsion, materials processing and fluid flow control, there is a need for improved, flexible diagnostic techniques suitable for use under the practical constraints imposed by plasma fields generated in a wide variety of aerospace devices. Much of the current diagnostic methodology in the engineering literature is based on analytical diagnostic, or forward, models. The Appleton-Hartree formula is an oft-used analytical relation for the refractive index of a cold, collisional plasma. Most of the assumptions underlying the model are applicable to diagnostics for plasma fields such as those found in Hall Thrusters and dielectric barrier discharge (DBD) plasma actuators. Among the assumptions is uniform material properties, this assumption is relaxed in the present research by introducing a flexible, numerical model of diagnostic wave propagation that can capture the effects of spatial gradients in the plasma state. The numerical approach is chosen for its flexibility in handling future extensions such as multiple spatial dimensions to account for scattering effects when the spatial extent of the plasma is small relative to the probing beam's width, and velocity dependent collision frequency for situations where the constant collision frequency assumption is not justified. The numerical wave propagation model (forward model) is incorporated into a general tomographic reconstruction framework that enables the combination of multiple interferometry measurements. The combined measurements provide a quantitative picture of the spatial variation in the plasma properties. The benefit of combining multiple measurements in a coherent

  4. Simulated plasma facing component measurements for an in situ surface diagnostic on Alcator C-Moda)

    Science.gov (United States)

    Hartwig, Z. S.; Whyte, D. G.

    2010-10-01

    The ideal in situ plasma facing component (PFC) diagnostic for magnetic fusion devices would perform surface element and isotope composition measurements on a shot-to-shot (˜10 min) time scale with ˜1 μm depth and ˜1 cm spatial resolution over large areas of PFCs. To this end, the experimental adaptation of the customary laboratory surface diagnostic—nuclear scattering of MeV ions—to the Alcator C-Mod tokamak is being guided by ACRONYM, a Geant4 synthetic diagnostic. The diagnostic technique and ACRONYM are described, and synthetic measurements of film thickness for boron-coated PFCs are presented.

  5. Optimum image compression rate maintaining diagnostic image quality of digital intraoral radiographs

    Energy Technology Data Exchange (ETDEWEB)

    Song, Ju Seop; Koh, Kwang Joon [Dept. of Oral and Maxillofacial Radiology and Institute of Oral Bio Science, School of Dentistry, Chonbuk National University, Chonju (Korea, Republic of)

    2000-12-15

    The aims of the present study are to determine the optimum compression rate in terms of file size reduction and diagnostic quality of the images after compression and evaluate the transmission speed of original or each compressed images. The material consisted of 24 extracted human premolars and molars. The occlusal surfaces and proximal surfaces of the teeth had a clinical disease spectrum that ranged from sound to varying degrees of fissure discoloration and cavitation. The images from Digora system were exported in TIFF and the images from conventional intraoral film were scanned and digitalized in TIFF by Nikon SF-200 scanner(Nikon, Japan). And six compression factors were chosen and applied on the basis of the results from a pilot study. The total number of images to be assessed were 336. Three radiologists assessed the occlusal and proximal surfaces of the teeth with 5-rank scale. Finally diagnosed as either sound or carious lesion by one expert oral pathologist. And sensitivity and specificity and kappa value for diagnostic agreement was calculated. Also the area (Az) values under the ROC curve were calculated and paired t-test and oneway ANOVA test was performed. Thereafter, transmission time of the image files of the each compression level were compared with that of the original image files. No significant difference was found between original and the corresponding images up to 7% (1:14) compression ratio for both the occlusal and proximal caries (p<0.05). JPEG3 (1:14) image files are transmitted fast more than 10 times, maintained diagnostic information in image, compared with original image files. 1:14 compressed image file may be used instead of the original image and reduce storage needs and transmission time.

  6. Multiphoton microscopy as a diagnostic imaging modality for lung cancer

    Science.gov (United States)

    Pavlova, Ina; Hume, Kelly R.; Yazinski, Stephanie A.; Peters, Rachel M.; Weiss, Robert S.; Webb, Watt W.

    2010-02-01

    Lung cancer is the leading killer among all cancers for both men and women in the US, and is associated with one of the lowest 5-year survival rates. Current diagnostic techniques, such as histopathological assessment of tissue obtained by computed tomography guided biopsies, have limited accuracy, especially for small lesions. Early diagnosis of lung cancer can be improved by introducing a real-time, optical guidance method based on the in vivo application of multiphoton microscopy (MPM). In particular, we hypothesize that MPM imaging of living lung tissue based on twophoton excited intrinsic fluorescence and second harmonic generation can provide sufficient morphologic and spectroscopic information to distinguish between normal and diseased lung tissue. Here, we used an experimental approach based on MPM with multichannel fluorescence detection for initial discovery that MPM spectral imaging could differentiate between normal and neoplastic lung in ex vivo samples from a murine model of lung cancer. Current results indicate that MPM imaging can directly distinguish normal and neoplastic lung tissues based on their distinct morphologies and fluorescence emission properties in non-processed lung tissue. Moreover, we found initial indication that MPM imaging differentiates between normal alveolar tissue, inflammatory foci, and lung neoplasms. Our long-term goal is to apply results from ex vivo lung specimens to aid in the development of multiphoton endoscopy for in vivo imaging of lung abnormalities in various animal models, and ultimately for the diagnosis of human lung cancer.

  7. Electron kinetic effects on optical diagnostics in fusion plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Mirnov, V. V.; Den Hartog, D. J.; Duff, J.; Parke, E. [University of Wisconsin-Madison and the Center for Magnetic Self-Organization in Laboratory and Astrophysical Plasmas, Madison, Wisconsin (United States); Brower, D. L., E-mail: vvmirnov@wisc.edu; Ding, W. X. [University of California Los Angeles, Los Angeles, California (United States)

    2014-08-21

    At anticipated high electron temperatures in ITER, the effects of electron thermal motion on Thomson scattering (TS), toroidal interferometer/polarimeter (TIP) and poloidal polarimeter (PoPola) diagnostics will be significant and must be accurately treated. We calculate electron thermal corrections to the interferometric phase and polarization state of an EM wave propagating along tangential and poloidal chords (Faraday and Cotton-Mouton polarimetry) and perform analysis of the degree of polarization for incoherent TS. The precision of the previous lowest order linear in τ = T{sub e}/m{sub e}c{sup 2} model may be insufficient; we present a more precise model with τ{sup 2}-order corrections to satisfy the high accuracy required for ITER TIP and PoPola diagnostics. The linear model is extended from Maxwellian to a more general class of anisotropic electron distributions that allows us to take into account distortions caused by equilibrium current, ECRH and RF current drive effects. The classical problem of degree of polarization of incoherent Thomson scattered radiation is solved analytically exactly without any approximations for the full range of incident polarizations, scattering angles, and electron thermal motion from non-relativistic to ultra-relativistic. The results are discussed in the context of the possible use of the polarization properties of Thomson scattered light as a method of T{sup e} measurement relevant to ITER operational scenarios.

  8. Assessing the value of diagnostic imaging: the role of perception

    Science.gov (United States)

    Potchen, E. J.; Cooper, Thomas G.

    2000-04-01

    The value of diagnostic radiology rests in its ability to provide information. Information is defined as a reduction in randomness. Quality improvement in any system requires diminution in the variation in its performance. The major variation in performance of the system of diagnostic radiology occurs in observer performance and in the communication of information from the observer to someone who will apply that information to the benefit of the patient. The ability to provide information can be determined by observer performance studies using a receiver-operating characteristic (ROC) curve analysis. The amount of information provided by each observer can be measured in terms of the uncertainty they reduce. Using a set of standardized radiographs, some normal and some abnormal, sorting them randomly, and then asking an observer to redistribute them according to their probability of normality can measure the difference in the value added by different observers. By applying this observer performance measure, we have been able to characterize individual radiologists, groups of radiologists, and regions of the United States in their ability to add value in chest radiology. The use of these technologies in health care may improve upon the contribution of diagnostic imaging.

  9. Optical diagnostic suite (schlieren, interferometry, and grid image refractometry) on OMEGA EP using a 10-ps, 263-nm probe beam

    Energy Technology Data Exchange (ETDEWEB)

    Froula, D. H.; Boni, R.; Bedzyk, M.; Craxton, R. S.; Ehrne, F.; Ivancic, S.; Jungquist, R.; Shoup, M. J.; Theobald, W.; Weiner, D. [Laboratory for Laser Energetics, University of Rochester, 250 E. River Rd., Rochester, New York 14616 (United States); Kugland, N. L.; Rushford, M. C. [Lawrence Livermore National Laboratory, University of California, P. O. Box 808, Livermore, California 94551 (United States)

    2012-10-15

    A 10-ps, 263-nm (4{omega}) laser is being built to probe plasmas produced on the OMEGA EP [J. H. Kelly, L. J. Waxer, V. Bagnoud, I. A. Begishev, J. Bromage, B. E. Kruschwitz, T. E. Kessler, S. J. Loucks, D. N. Maywar, R. L. McCrory et al., J. Phys. IV France 133, 75-80 (2006)]. A suite of optical diagnostics (schlieren, interferometry, and grid image refractometry) has been designed to diagnose and characterize a wide variety of plasmas. Light scattered by the probe beam is collected by an f/4 catadioptric telescope and a transport system is designed to image with a near-diffraction-limited resolution ({approx}1 -{mu}m full width at half maximum) over a 5-mm field of view to a diagnostic table. The transport system provides a contrast greater than 1 : 10{sup 4} with respect to all wavelengths outside of the 263 {+-} 2 nm measurement range.

  10. Optical diagnostic suite (schlieren, interferometry, and grid image refractometry) on OMEGA EP using a 10-ps, 263-nm probe beam

    Energy Technology Data Exchange (ETDEWEB)

    Froula, D. H.; Boni, R.; Bedzyk, M.; Craxton, R. S.; Ehrne, F.; Ivancic, S.; Jungquist, R.; Shoup, M. J.; Theobald, W.; Weiner, D.; Kugland, N. L.; Rushford, M. C.

    2012-10-01

    A 10-ps, 263-nm (4ω) laser is being built to probe plasmas produced on the OMEGA EP. A suite of optical diagnostics (schlieren, interferometry, and grid image refractometry) has been designed to diagnose and characterize a wide variety of plasmas. Light scattered by the probe beam is collected by an f/4 catadioptric telescope and a transport system is designed to image with a near-diffraction-limited resolution (~1 - μm full width at half maximum) over a 5-mm field of view to a diagnostic table. The transport system provides a contrast greater than 1 : 104 with respect to all wavelengths outside of the 263 ± 2 nm measurement range.

  11. Optical diagnostic suite (schlieren, interferometry, and grid image refractometry) on OMEGA EP using a 10-ps, 263-nm probe beam.

    Science.gov (United States)

    Froula, D H; Boni, R; Bedzyk, M; Craxton, R S; Ehrne, F; Ivancic, S; Jungquist, R; Shoup, M J; Theobald, W; Weiner, D; Kugland, N L; Rushford, M C

    2012-10-01

    A 10-ps, 263-nm (4ω) laser is being built to probe plasmas produced on the OMEGA EP [J. H. Kelly, L. J. Waxer, V. Bagnoud, I. A. Begishev, J. Bromage, B. E. Kruschwitz, T. E. Kessler, S. J. Loucks, D. N. Maywar, R. L. McCrory et al., J. Phys. IV France 133, 75-80 (2006)]. A suite of optical diagnostics (schlieren, interferometry, and grid image refractometry) has been designed to diagnose and characterize a wide variety of plasmas. Light scattered by the probe beam is collected by an f/4 catadioptric telescope and a transport system is designed to image with a near-diffraction-limited resolution (~1 - μm full width at half maximum) over a 5-mm field of view to a diagnostic table. The transport system provides a contrast greater than 1 : 10(4) with respect to all wavelengths outside of the 263 ± 2 nm measurement range.

  12. Laser Diagnostics Study of Plasma Assisted Combustion for Scramjet Applications

    Science.gov (United States)

    2011-12-01

    treatment of the fuel or reactants into hydrogen rich syngas prior to thermal oxidation [11-12], enhanced ignition of hydrocarbon fuels [9,13-14...dramatically, and a significant rise of OH in the post combustion gas region is evident. It is 532 nm Power Supply N d: YA G L as er Dye Laser...plasma, ne~1014-1015 cm-3). The power supply is a 2 kW magnetron (2.45 GHz), although no more than 40 W seems to be required for most test conditions due

  13. Meeting the Needs for Radiation Protection: Diagnostic Imaging.

    Science.gov (United States)

    Frush, Donald P

    2017-02-01

    Radiation and potential risk during medical imaging is one of the foremost issues for the imaging community. Because of this, there are growing demands for accountability, including appropriate use of ionizing radiation in diagnostic and image-guided procedures. Factors contributing to this include increasing use of medical imaging; increased scrutiny (from awareness to alarm) by patients/caregivers and the public over radiation risk; and mounting calls for accountability from regulatory, accrediting, healthcare coverage (e.g., Centers for Medicare and Medicaid Services), and advisory agencies and organizations as well as industry (e.g., NEMA XR-29, Standard Attributes on CT Equipment Related to Dose Optimization and Management). Current challenges include debates over uncertainty with risks with low-level radiation; lack of fully developed and targeted products for diagnostic imaging and radiation dose monitoring; lack of resources for and clarity surrounding dose monitoring programs; inconsistencies across and between practices for design, implementation and audit of dose monitoring programs; lack of interdisciplinary programs for radiation protection of patients; potential shortages in personnel for these and other consensus efforts; and training concerns as well as inconsistencies for competencies throughout medical providers' careers for radiation protection of patients. Medical care providers are currently in a purgatory between quality- and value-based imaging paradigms, a state that has yet to mature to reward this move to quality-based performance. There are also deficits in radiation expertise personnel in medicine. For example, health physics academic programs and graduates have recently declined, and medical physics residency openings are currently at a third of the number of graduates. However, leveraging solutions to the medical needs will require money and resources, beyond personnel alone. Energy and capital will need to be directed to

  14. Diagnostic value of plasma aldosterone/potassium ratio in hypoaldosteronism.

    Science.gov (United States)

    Shiah, C J; Wu, K D; Tsai, D M; Liao, S T; Siauw, C P; Lee, L S

    1995-05-01

    The diagnosis of hypoaldosteronism usually depends upon a combination of abnormal clinical and laboratory findings. The most common abnormality in hypoaldosteronism is hyperkalemia, which may be combined with sodium depletion. In the present study, 5 of 16 patients diagnosed with isolated hypoaldosteronism (IHA) had sodium depletion due to renal salt wasting, and four patients had normokalemia. Of these 16 IHA patients, 70% had subnormal baseline and stimulated plasma renin activity (PRA). Six patients diagnosed with type I pseudohypoaldosteronism (PHA) had normal or high PRA and plasma aldosterone concentrations (PAC). In 11 control subjects, supine PAC correlated positively with serum potassium (SK), and PAC stimulated by furosemide and ambulation correlated with the 24-hour urinary potassium excretion (UK). However, these correlations were not found in IHA and PHA patients. The ratio of UK/UNa+K and UNa/UK correlated with the stimulated PAC when the IHA and control subjects were taken as a whole. However, these electrolyte excretion parameters bore no relationship to the supine PAC. The stimulated PAC/SK ratio was used to discriminate the three groups; all IHA patients had a ratio below 3. The results indicate that stimulated PAC reflects the bioactivity of aldosterone on the collecting tubule, and the stimulated PAC/SK ratio is useful for the diagnosis of hypoaldosteronism and pseudohypoaldosteronism.

  15. Magnetic nanoparticles in magnetic resonance imaging and diagnostics.

    Science.gov (United States)

    Rümenapp, Christine; Gleich, Bernhard; Haase, Axel

    2012-05-01

    Magnetic nanoparticles are useful as contrast agents for magnetic resonance imaging (MRI). Paramagnetic contrast agents have been used for a long time, but more recently superparamagnetic iron oxide nanoparticles (SPIOs) have been discovered to influence MRI contrast as well. In contrast to paramagnetic contrast agents, SPIOs can be functionalized and size-tailored in order to adapt to various kinds of soft tissues. Although both types of contrast agents have a inducible magnetization, their mechanisms of influence on spin-spin and spin-lattice relaxation of protons are different. A special emphasis on the basic magnetism of nanoparticles and their structures as well as on the principle of nuclear magnetic resonance is made. Examples of different contrast-enhanced magnetic resonance images are given. The potential use of magnetic nanoparticles as diagnostic tracers is explored. Additionally, SPIOs can be used in diagnostic magnetic resonance, since the spin relaxation time of water protons differs, whether magnetic nanoparticles are bound to a target or not.

  16. Dust dynamics and diagnostic applications in quasi-neutral plasmas and magnetic fusion

    Science.gov (United States)

    Wang, Zhehui; Ticos, Catalin M.; Si, Jiahe; Delzanno, Gian Luca; Lapenta, Gianni; Wurden, Glen

    2007-11-01

    Little is known about dust dynamics in highly ionized quasi-neutral plasmas with ca. 1.0 e+20 per cubic meter density and ion temperature at a few eV and above, including in magnetic fusion. For example, dust motion in fusion, better known as UFO's, has been observed since 1980's but not explained. Solid understanding of dust dynamics is also important to International Thermonuclear Experimental Reactor (ITER) because of concerns about safety and dust contamination of fusion core. Compared with well studied strongly-coupled dusty plasma regime, new physics may arise in the higher density quasi-neutral plasma regime because of at least four orders of magnitude higher density and two orders of magnitude hotter ion temperature. Our recent laboratory experiments showed that plasma-flow drag force dominates over other forces in a quasi-neutral flowing plasma. In contrast, delicate balance among different forces in dusty plasma has led to many unique phenomena, in particular, the formation of dust crystal. Based on our experiments, we argue that 1) dust crystal will not form in the highly ionized plasmas with flows; 2) the UFO's are moving dust dragged by plasma flows; 3) dust can be used to measure plasma flow. Two diagnostic applications using dust for laboratory quasi-neutral plasmas and magnetic fusion will also be presented.

  17. Plasma plume diagnostics of low power stationary plasma thruster (SPT-20M8) with collisional radiative model

    Science.gov (United States)

    Uttamsing Rajput, Rajendrasing; Alona, Khaustova; Loyan, Andriy V.

    2017-03-01

    Electric propulsion offers higher specific impulse compared to the chemical propulsion systems. It reduces the overall propellant mass and enables high operational lifetimes. Scientific Technological Center of Space Power and Energy (STC SPE), KhAI is involved in designing, manufacturing and testing of stationary plasma thrusters (SPT). Efforts are made to perform plasma diagnostics with corona and collisional radiative models (C-R model), as expected corona model falls short below 4 eV because of the heavy particle collisions elimination, whereas the C-R model's applicability is confirmed. Several tests are performed to analyze the electron temperature at various operational parameters of thruster like discharge voltage and mass flow rate. SPT-20M8 far and near-field plumes diagnostics are performed. Feasibility of C-R model by comparing its result to optical emission spectroscopy (OES) to investigate the electron temperature is validated with the probe measurements within the 10% of discrepancy.

  18. FAR-TECH's Nanoparticle Plasma Jet System and its Application to Disruptions, Deep Fueling, and Diagnostics

    Science.gov (United States)

    Thompson, J. R.; Bogatu, I. N.; Galkin, S. A.; Kim, J. S.

    2012-10-01

    Hyper-velocity plasma jets have potential applications in tokamaks for disruption mitigation, deep fueling and diagnostics. Pulsed power based solid-state sources and plasma accelerators offer advantages of rapid response and mass delivery at high velocities. Fast response is critical for some disruption mitigation scenario needs, while high velocity is especially important for penetration into tokamak plasma and its confining magnetic field, as in the case of deep fueling. FAR-TECH is developing the capability of producing large-mass hyper-velocity plasma jets. The prototype solid-state source has produced: 1) >8.4 mg of H2 gas only, and 2) >25 mg of H2 and >180 mg of C60 in a H2/C60 gas mixture. Using a coaxial plasma gun coupled to the source, we have successfully demonstrated the acceleration of composite H/C60 plasma jets, with momentum as high as 0.6 g.km/s, and containing an estimated C60 mass of ˜75 mg. We present the status of FAR-TECH's nanoparticle plasma jet system and discuss its application to disruptions, deep fueling, and diagnostics. A new TiH2/C60 solid-state source capable of generating significantly higher quantities of H2 and C60 in <0.5 ms will be discussed.

  19. Image processing methods and architectures in diagnostic pathology.

    Directory of Open Access Journals (Sweden)

    Oscar DĂŠniz

    2010-05-01

    Full Text Available Grid technology has enabled the clustering and the efficient and secure access to and interaction among a wide variety of geographically distributed resources such as: supercomputers, storage systems, data sources, instruments and special devices and services. Their main applications include large-scale computational and data intensive problems in science and engineering. General grid structures and methodologies for both software and hardware in image analysis for virtual tissue-based diagnosis has been considered in this paper. This methods are focus on the user level middleware. The article describes the distributed programming system developed by the authors for virtual slide analysis in diagnostic pathology. The system supports different image analysis operations commonly done in anatomical pathology and it takes into account secured aspects and specialized infrastructures with high level services designed to meet application requirements. Grids are likely to have a deep impact on health related applications, and therefore they seem to be suitable for tissue-based diagnosis too. The implemented system is a joint application that mixes both Web and Grid Service Architecture around a distributed architecture for image processing. It has shown to be a successful solution to analyze a big and heterogeneous group of histological images under architecture of massively parallel processors using message passing and non-shared memory.

  20. Plasma Diagnostics of the Interstellar Medium with Radio Astronomy

    CERN Document Server

    Haverkorn, Marijke

    2013-01-01

    We discuss the degree to which radio propagation measurements diagnose conditions in the ionized gas of the interstellar medium (ISM). The "signal generators" of the radio waves of interest are extragalactic radio sources (quasars and radio galaxies), as well as Galactic sources, primarily pulsars. The polarized synchrotron radiation of the Galactic non-thermal radiation also serves to probe the ISM, including space between the emitting regions and the solar system. Radio propagation measurements provide unique information on turbulence in the ISM as well as the mean plasma properties such as density and magnetic field strength. Radio propagation observations can provide input to the major contemporary questions on the nature of ISM turbulence, such as its dissipation mechanisms and the processes responsible for generating the turbulence on large spatial scales. Measurements of the large scale Galactic magnetic field via Faraday rotation provide unique observational input to theories of the generation of the ...

  1. Thermoacoustic imaging and spectroscopy for enhanced cancer diagnostics

    Science.gov (United States)

    Bauer, Daniel Ryan

    Early detection of cancer is paramount for improved patient survival. This dissertation presents work developing imaging techniques to improve cancer diagnostics and detection utilizing light and microwave induced thermoacoustic imaging. In the second chapter, the well-established pre-clinical mouse window chamber model is interfaced with simultaneously acquired high-resolution pulse echo (PE) ultrasound and photoacoustic (PA) imaging. Co-registered PE and PA imaging, coupled with developed image segmentation algorithms, are used to quantitatively track and monitor the size, shape, heterogeneity, and neovasculature of the tumor microenvironment during a month long study. Average volumetric growth was 5.35 mm3/day, which correlated well with two dimensional results from fluorescent imaging (R = 0.97, p imaging is also employed to probe the assumed oxygenation status of the tumor vasculature. The window chamber model combined with high-resolution PE and PA imaging could form a powerful testbed for characterizing cancers and evaluating new contrast and therapeutic agents. The third chapter utilizes a clinical ultrasound array to facilitate fast volumetric spectroscopic PA imaging to detect and discriminate endogenous absorbers (i.e. oxy/deoxygenated hemoglobin) as well as exogenous PA contrast agents (i.e. gold nanorods, fluorophores). In vivo spatiotemporal tracking of administered gold nanorods is presented, with the contrast agent augmenting the PA signal 18 dB. Furthermore, through the use of spectral unmixing algorithms, the relative concentrations of multiple endogenous and exogenous co-localized absorbers were reconstructed in tumor bearing mice. The concentration of Alexaflour647 was calculated to increase nearly 20 dB in the center of a prostate tumor after a tail-vein injection of the contrast agent. Additionally, after direct subcutaneous injections of two different gold nanorods into a breast tumor, the concentration of each nanoparticle was discriminated

  2. Diagnostic imaging of psoriatic arthritis. Part II: magnetic resonance imaging and ultrasonography.

    Science.gov (United States)

    Sudoł-Szopińska, Iwona; Pracoń, Grzegorz

    2016-06-01

    Plain radiography reveals specific, yet late changes of advanced psoriatic arthritis. Early inflammatory changes are seen both on magnetic resonance imaging and ultrasound within peripheral joints (arthritis, synovitis), tendons sheaths (tenosynovitis, tendovaginitis) and entheses (enthesitis, enthesopathy). In addition, magnetic resonance imaging enables the assessment of inflammatory features in the sacroiliac joints (sacroiliitis), and the spine (spondylitis). In this article, we review current opinions on the diagnostics of some selective, and distinctive features of psoriatic arthritis concerning magnetic resonance imaging and ultrasound and present some hypotheses on psoriatic arthritis etiopathogenesis, which have been studied with the use of magnetic resonance imaging. The following elements of the psoriatic arthritis are discussed: enthesitis, extracapsular inflammation, dactylitis, distal interphalangeal joint and nail disease, and the ability of magnetic resonance imaging to differentiate undifferentiated arthritis, the value of whole-body magnetic resonance imaging and dynamic contrast-enhanced magnetic resonance imaging.

  3. Diagnostic imaging of psoriatic arthritis. Part II: magnetic resonance imaging and ultrasonography

    Directory of Open Access Journals (Sweden)

    Iwona Sudoł-Szopińska

    2016-06-01

    Full Text Available Plain radiography reveals specific, yet late changes of advanced psoriatic arthritis. Early inflammatory changes are seen both on magnetic resonance imaging and ultrasound within peripheral joints (arthritis, synovitis, tendons sheaths (tenosynovitis, tendovaginitis and entheses (enthesitis, enthesopathy. In addition, magnetic resonance imaging enables the assessment of inflammatory features in the sacroiliac joints (sacroiliitis, and the spine (spondylitis. In this article, we review current opinions on the diagnostics of some selective, and distinctive features of psoriatic arthritis concerning magnetic resonance imaging and ultrasound and present some hypotheses on psoriatic arthritis etiopathogenesis, which have been studied with the use of magnetic resonance imaging. The following elements of the psoriatic arthritis are discussed: enthesitis, extracapsular inflammation, dactylitis, distal interphalangeal joint and nail disease, and the ability of magnetic resonance imaging to differentiate undifferentiated arthritis, the value of whole-body magnetic resonance imaging and dynamic contrast-enhanced magnetic resonance imaging.

  4. [Plasma cholesterol determination in birds--a diagnostic tool for detection of organophosphate and carbamate intoxication].

    Science.gov (United States)

    Kiesau, B; Kummerfeld, N

    1998-07-01

    An investigation was done on the clinical usefulness of the dry chemistry analyzer Vitros DT 60 II for determination of avian plasma cholinesterase. The analytical reliability of the method, evaluated by precision and accuracy, proved to be high for plasma of numerous pet and wild birds. Values of normal plasma-cholinesterase activity were established for different psittacine and European wild birds. Significant differences in physiologic plasma-cholinesterase activity were noted between closely related species as well as between juvenile and adult birds. These findings emphasize the necessity to use control values of the same species and age group for comparison. Dry chemistry plasma-cholinesterase determination can be used as a diagnostic tool for detection of organophosphate and carbamate poisonings in the majority of investigated birds.

  5. VUV diagnostic of electron impact processes in low temperature molecular hydrogen plasma

    CERN Document Server

    Komppula, J

    2015-01-01

    Novel methods for diagnostics of molecular hydrogen plasma processes, such as ionization, production of high vibrational levels, dissociation of molecules via excitation to singlet and triplet states and production of metastable states, are presented for molecular hydrogen plasmas in corona equilibrium. The methods are based on comparison of rate coefficients of plasma processes and optical emission spectroscopy of lowest singlet and triplet transitions, i.e. Lyman-band ($B^1\\Sigma^+_u \\rightarrow X^1\\Sigma^+_g$) and molecular continuum ($a^3\\Sigma^+_g \\rightarrow b^3\\Sigma^+_u$), of the hydrogen molecule in VUV wavelength range. Comparison of rate coefficients of spin-allowed and/or spin-forbidden excitations reduces the uncertainty caused by the non-equilibrium distributions of electron energy and molecular vibrational level, which are typically known poorly in plasma sources. The described methods are applied to estimate the rates of various plasma processes in a filament arc discharge.

  6. Microwave Diagnostics for Studies of Electromagnetic Scattering by Fluorescent Lamp Plasma

    Institute of Scientific and Technical Information of China (English)

    Xiang HE; Jian-ping CHEN; Ying WU; Yu-dong CHEN; Xiao-jun ZENC; Hai-chao QIN; Xiao-wu NI

    2010-01-01

    This gaper reports a related microwave diagnostic method that measures both the electron number density and the electron-neutral collision frequency,which are crucial to understand the behavior of microwave traveling in plasma.Arrays of standard commerci fluorescent lamp placed directly against each other in two rows are used to peoduce a plasma layer.Attenuations of microwave by plasma layer are studied experimentally in the frequencies of 1~8 GHz using a synthesized signal generator and a spectrum analyzer.Two wave-polarizations are under investigation:electric field of the wave is either parallel(E-wave)or perprndicular(H-wave)to the fluorescent lamp axis.The electron number density and the electron-neutral collision frequensy of fluorescent lamp plasma are obtained by microwave diagnstics,for the purpose of analyzing microwave scattering characteristics by plasma.

  7. Backreflection diagnostics for ultra-intense laser plasma experiments based on frequency resolved optical gating

    Science.gov (United States)

    Wagner, F.; Hornung, J.; Schmidt, C.; Eckhardt, M.; Roth, M.; Stöhlker, T.; Bagnoud, V.

    2017-02-01

    We report on the development and implementation of a time resolved backscatter diagnostics for high power laser plasma experiments at the petawatt-class laser facility PHELIX. Pulses that are backscattered or reflected from overcritical plasmas are characterized spectrally and temporally resolved using a specially designed second harmonic generation frequency resolved optical gating system. The diagnostics meets the requirements made by typical experiments, i.e., a spectral bandwidth of more than 30 nm with sub-nanometer resolution and a temporal window of 10 ps with 50 fs temporal resolution. The diagnostics is permanently installed at the PHELIX target area and can be used to study effects such as laser-hole boring or relativistic self-phase-modulation which are important features of laser-driven particle acceleration experiments.

  8. Plasma diagnostics in gas metal arc welding by optical emission spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Valensi, F; Pellerin, S; Zielinska, S [GREMI, Universite d' Orleans (Site de Bourges)/CNRS, BP 4043, 18028 Bourges cedex (France); Boutaghane, A [Universite des Sciences et de la Technologie Houari Boumediene, Alger (Algeria); Dzierzega, K [Marian Smoluchowski Institute of Physics, Jagellonian University, Krakow (Poland); Pellerin, N [CNRS, UPR3079 CEMHTI, 1D av. de la Recherche Scientifique, 45071 Orleans cedex 2 (France); Briand, F, E-mail: flavien.valensi@laplace.univ-tsle.f, E-mail: stephane.pellerin@univ-orleans.f, E-mail: aboutaghane@yahoo.f, E-mail: krzycho@netmail.if.uj.edu.p, E-mail: sylwia.zielinska@airliquide.co, E-mail: nadia.pellerin@univ-orleans.f, E-mail: francis.briand@airliquide.co [CTAS-Air Liquide Welding, Saint Ouen l' Aumone, 95315 Cergy-Pontoise cedex (France)

    2010-11-03

    The plasma column in a metal inert gas welding process is investigated by optical emission spectroscopy and high-speed imaging. The concentration and repartition of iron vapours are measured and correlated with the plasma and electrode geometric configuration. Plasma temperatures and electron densities are also measured for each studied position in the plasma. The temperatures are calculated using two different methods, allowing validation of the local thermodynamic equilibrium state of the plasma. The results show a maximum temperature of 12 500 K in the upper part of the arc, away from the arc axis. The iron concentration reaches a maximum of 0.3% close to the anode and strongly decreases along both the vertical and radial directions. The plasma thermophysical properties, calculated from this plasma composition, are then discussed regarding the metal transfer mode.

  9. Image-guided plasma therapy of cutaneous wound

    Science.gov (United States)

    Zhang, Zhiwu; Ren, Wenqi; Yu, Zelin; Zhang, Shiwu; Yue, Ting; Xu, Ronald

    2014-02-01

    The wound healing process involves the reparative phases of inflammation, proliferation, and remodeling. Interrupting any of these phases may result in chronically unhealed wounds, amputation, or even patient death. Despite the clinical significance in chronic wound management, no effective methods have been developed for quantitative image-guided treatment. We integrated a multimodal imaging system with a cold atmospheric plasma probe for image-guided treatment of chronic wound. Multimodal imaging system offers a non-invasive, painless, simultaneous and quantitative assessment of cutaneous wound healing. Cold atmospheric plasma accelerates the wound healing process through many mechanisms including decontamination, coagulation and stimulation of the wound healing. The therapeutic effect of cold atmospheric plasma is studied in vivo under the guidance of a multimodal imaging system. Cutaneous wounds are created on the dorsal skin of the nude mice. During the healing process, the sample wound is treated by cold atmospheric plasma at different controlled dosage, while the control wound is healed naturally. The multimodal imaging system integrating a multispectral imaging module and a laser speckle imaging module is used to collect the information of cutaneous tissue oxygenation (i.e. oxygen saturation, StO2) and blood perfusion simultaneously to assess and guide the plasma therapy. Our preliminary tests show that cold atmospheric plasma in combination with multimodal imaging guidance has the potential to facilitate the healing of chronic wounds.

  10. Overview of the electric propulsion plasma diagnostics suite for the VASIMR VX-200 testbed

    Science.gov (United States)

    Olsen, Christopher; Longmier, Benjamin; Ballenger, Maxwell; Squire, Jared; Glover, Tim; Carter, Mark; Bering, Edgar; Giambusso, Matthew

    2012-10-01

    Descriptions of the various plasma diagnostics and data analysis methods are given for instruments used in high power (> 100 kW) electric propulsion testing. These include planar Langmuir probes, an articulating retarding potential analyzer, a double Langmuir probe, a multi-axis magnetometer, a high frequency electric field probe, microwave interferometer, and momentum flux targets. These diagnostics have been used to measure the efficiencies of the thruster, plasma source, ion cyclotron resonance booster, and magnetic nozzle as well as used to explore physical phenomena in the plume such as ion/electron detachment, plasma turbulence, and magnetic field line stretching. Typical plume parameters range up to 10^13 cm-3 electron density, 1 kG applied magnetic fields, ion energies in excess of 150 eV, and cold electrons (2 -- 5 eV) with a spatial measurement range over 2 m.

  11. Gold Nanoconstructs for Multimodal Diagnostic Imaging and Photothermal Cancer Therapy

    Science.gov (United States)

    Coughlin, Andrew James

    Cancer accounts for nearly 1 out of every 4 deaths in the United States, and because conventional treatments are limited by morbidity and off-target toxicities, improvements in cancer management are needed. This thesis further develops nanoparticle-assisted photothermal therapy (NAPT) as a viable treatment option for cancer patients. NAPT enables localized ablation of disease because heat generation only occurs where tissue permissive near-infrared (NIR) light and absorbing nanoparticles are combined, leaving surrounding normal tissue unharmed. Two principle approaches were investigated to improve the specificity of this technique: multimodal imaging and molecular targeting. Multimodal imaging affords the ability to guide NIR laser application for site-specific NAPT and more holistic characterization of disease by combining the advantages of several diagnostic technologies. Towards the goal of image-guided NAPT, gadolinium-conjugated gold-silica nanoshells were engineered and demonstrated to enhance imaging contrast across a range of diagnostic modes, including T1-weighted magnetic resonance imaging, X-Ray, optical coherence tomography, reflective confocal microscopy, and two-photon luminescence in vitro as well as within an animal tumor model. Additionally, the nanoparticle conjugates were shown to effectively convert NIR light to heat for applications in photothermal therapy. Therefore, the broad utility of gadolinium-nanoshells for anatomic localization of tissue lesions, molecular characterization of malignancy, and mediators of ablation was established. Molecular targeting strategies may also improve NAPT by promoting nanoparticle uptake and retention within tumors and enhancing specificity when malignant and normal tissue interdigitate. Here, ephrinA1 protein ligands were conjugated to nanoshell surfaces for particle homing to overexpressed EphA2 receptors on prostate cancer cells. In vitro, successful targeting and subsequent photothermal ablation of

  12. Targeted diagnostic magnetic nanoparticles for medical imaging of pancreatic cancer.

    Science.gov (United States)

    Rosenberger, I; Strauss, A; Dobiasch, S; Weis, C; Szanyi, S; Gil-Iceta, L; Alonso, E; González Esparza, M; Gómez-Vallejo, V; Szczupak, B; Plaza-García, S; Mirzaei, S; Israel, L L; Bianchessi, S; Scanziani, E; Lellouche, J-P; Knoll, P; Werner, J; Felix, K; Grenacher, L; Reese, T; Kreuter, J; Jiménez-González, M

    2015-09-28

    Highly aggressive cancer types such as pancreatic cancer possess a mortality rate of up to 80% within the first 6months after diagnosis. To reduce this high mortality rate, more sensitive diagnostic tools allowing an early stage medical imaging of even very small tumours are needed. For this purpose, magnetic, biodegradable nanoparticles prepared using recombinant human serum albumin (rHSA) and incorporated iron oxide (maghemite, γ-Fe2O3) nanoparticles were developed. Galectin-1 has been chosen as target receptor as this protein is upregulated in pancreatic cancer and its precursor lesions but not in healthy pancreatic tissue nor in pancreatitis. Tissue plasminogen activator derived peptides (t-PA-ligands), that have a high affinity to galectin-1 have been chosen as target moieties and were covalently attached onto the nanoparticle surface. Improved targeting and imaging properties were shown in mice using single photon emission computed tomography-computer tomography (SPECT-CT), a handheld gamma camera, and magnetic resonance imaging (MRI).

  13. PREFACE: IX International Conference on Modern Techniques of Plasma Diagnostics and their Application

    Science.gov (United States)

    Savjolov, A. S.; Dodulad, E. I.

    2016-01-01

    The IX Conference on ''Modern Techniques of Plasma Diagnosis and their Application'' was held on 5 - 7 November, 2014 at National Research Nuclear University MEPhI (NRNU MEPhI). The goal of the conference was an exchange of information on both high-temperature and low-temperature plasma diagnostics as well as deliberation and analysis of various diagnostic techniques and their applicability in science, industry, ecology, medicine and other fields. The Conference also provided young scientists from scientific centres and universities engaged in plasma diagnostics with an opportunity to attend the lectures given by the leading specialists in this field as well as present their own results and findings. The first workshop titled ''Modern problems of plasma diagnostics and their application for control of chemicals and the environment'' took place at Moscow Engineering and Physics Institute (MEPhI) in June 1998 with the support of the Section on Diagnostics of the Council of Russian Academic of Science on Plasma Physics and since then these forums have been held at MEPhI every two years. In 2008 the workshop was assigned a conference status. More than 150 specialists on plasma diagnostics and students took part in the last conference. They represented leading Russian scientific centres (such as Troitsk Institute of Innovative and Thermonuclear Research, National Research Centre ''Kurchatov Institute'', Russian Federal Nuclear Centre - All-Russian Scientific Research Institute of Experimental Physics and others) and universities from Belarus, Ukraine, Germany, USA, Belgium and Sweden. About 30 reports were made by young researchers, students and post-graduate students. All presentations during the conference were broadcasted online over the internet with viewers in Moscow, Prague, St. Petersburgh and other cities. The Conference was held within the framework of the Centre of Plasma, Laser Research and Technology supported by MEPhI Academic Excellence Project (Russian

  14. The Multiple Resonance Probe: A Novel Device for Industry Compatible Plasma Diagnostics

    Science.gov (United States)

    Brinkmann, Ralf Peter; Storch, Robert; Lapke, Martin; Oberrath, Jens; Schulz, Christian; Styrnoll, Tim; Zietz, Christian; Awakowicz, Peter; Musch, Thomas; Mussenbrock, Thomas; Rolfes, Ilona

    2012-10-01

    To be useful for the supervision or control of technical plasmas, a diagnostic method must be i) robust and stable, ii) insensitive to perturbation by the process, iii) itself not perturbing the process, iv) clearly and easily interpretable without the need for calibration, v) compliant with the requirements of process integration, and, last but not least, vi) economical in terms of investment, footprint, and maintenance. Plasma resonance spectroscopy, exploiting the natural ability of plasmas to resonate on or near the electron plasma frequency, provides a good basis for such an ``industry compatible'' plasma diagnostics. The contribution will describe the general idea of active plasma resonance spectroscopy and introduce a mathematical formalism for its analysis. It will then focus on the novel multipole resonance probe (MRP), where the excited resonances can be classified explicitly and the connection between the probe response and the desired electron density can be cast as a simple formula. The current state of the MRP project will be described, including the experimental characterization of a prototype in comparison with Langmuir probes, and the development of a specialized measurement circuit.

  15. Radial scanning diagnostics of bremsstrahlung and line emission in T-10 plasma

    Energy Technology Data Exchange (ETDEWEB)

    Nemets, A. R., E-mail: Nemets-AR@nrcki.ru; Krupin, V. A.; Klyuchnikov, L. A., E-mail: lklyuchnikov@list.ru; Korobov, K. V.; Nurgaliev, M. R. [National Research Centre Kurchatov Institute, Institute of Tokamak Physics (Russian Federation)

    2016-12-15

    The paper describes the scanning spectroscopic diagnostics designed for measurement of line integrated plasma radiation in two visible spectral ranges. This diagnostic system is aimed at measuring the bremsstrahlung absolute values and profile with high spatial resolution. The bremsstrahlung absolute values are used to determine the value and radial distribution of effective plasma ion charge Z{sub eff}(r) in T-10 discharges. The importance of Z{sub eff} measurement is due to its strong influence on plasma heating, confinement, and stability. The spatial distribution of emission for one of the chosen spectral lines is measured simultaneously with bremsstrahlung. The spatial resolution of measurements is ~1 cm, and the temporal resolution is up to 10 ms. The spectral equipment and methods for its calibration are described. Examples of line integrated brightness distribution in a “continuum window” of 5236 ± 6 Å and brightness of the lines C{sup 5+} (5291 Å), He{sup 1+} (4686 Å), and D{sub β} (4861 Å) are given. Flattening of the bremsstrahlung brightness profile in the central region of the plasma column in some discharges with sawtooth oscillations in the T-10 is observed. The measured effective ion charge profiles in ohmic discharges with high plasma density and low discharge currents demonstrate accumulation of light impurities at the column axis; as a consequence, quenching of sawtooth oscillations in some discharges is observed. The developed diagnostics provides necessary data for investigation of heat, particle, and current transport in the plasma of the T-10. Successful application of the obtained data on Z{sub eff}(r) for investigation of geodesic acoustic modes of plasma oscillations in the T-10 should be specially noted.

  16. Multiframe, Single Line-of-Sight X-Ray Imager for Burning Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Baker, Kevin L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-01-28

    The purpose of this LDRD project was to demonstrate high spatial and temporal resolution x-ray imaging using optical detectors, and in particular the VISAR and OHRV diagnostics on the OMEGA laser. The x-ray source being imaged was a backlighter capsule being imploded by 39 beams of the OMEGA laser. In particular this approach utilized a semiconductor with the side facing the backlighter capsule coated with a thin aluminum layer to allow x rays to pass through the metal layer and then get absorbed in the semiconductor. The other side of the semiconductor was AR coated to allow the VISAR or OHRV probe beam to sample the phase change of the semiconductor as the x rays were absorbed in the semiconductor. This technique is capable of acquiring sub-picosecond 2-D or 1-D x-ray images, detector spatial resolution of better than 10 um and the ability to operate in a high neutron flux environment expected on ignition shots with burning plasmas. In addition to demonstrating this technique on the OMEGA laser, several designs were made to improve the phase sensitivity, temporal resolution and number of frames over the existing diagnostics currently implemented on the OMEGA laser. These designs included both 2-d imaging diagnostics as well as improved 1-D imaging diagnostics which were streaked in time.

  17. Infrared imaging diagnostics for intense pulsed electron beam

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Xiao; Shen, Jie; Liu, Wenbin; Zhong, Haowen; Zhang, Jie; Zhang, Gaolong; Le, Xiaoyun, E-mail: xyle@buaa.edu.cn [School of Physics and Nuclear Energy Engineering, Beihang University, Beijing 100191 (China); International Research Center for Nuclei and Particles in the Cosmos, Beihang University, Beijing 100191 (China); Qu, Miao; Yan, Sha [Institute of Heavy Ion Physics, Peking University, Beijing 100871 (China)

    2015-08-15

    Infrared imaging diagnostic method for two-dimensional calorimetric diagnostics has been developed for intense pulsed electron beam (IPEB). By using a 100-μm-thick tungsten film as the infrared heat sink for IPEB, the emitting uniformity of the electron source can be analyzed to evaluate the efficiency and stability of the diode system. Two-dimensional axisymmetric finite element method heat transfer simulation, combined with Monte Carlo calculation, was performed for error estimation and optimization of the method. The test of the method was finished with IPEB generated by explosive emission electron diode with pulse duration (FWHM) of 80 ns, electron energy up to 450 keV, and a total beam current of over 1 kA. The results showed that it is possible to measure the cross-sectional energy density distribution of IPEB with energy sensitivity of 0.1 J/cm{sup 2} and spatial resolution of 1 mm. The technical details, such as irradiation protection of bremsstrahlung γ photons and the functional extensibility of the method were discussed in this work.

  18. Infrared imaging diagnostics for intense pulsed electron beam.

    Science.gov (United States)

    Yu, Xiao; Shen, Jie; Qu, Miao; Liu, Wenbin; Zhong, Haowen; Zhang, Jie; Yan, Sha; Zhang, Gaolong; Le, Xiaoyun

    2015-08-01

    Infrared imaging diagnostic method for two-dimensional calorimetric diagnostics has been developed for intense pulsed electron beam (IPEB). By using a 100-μm-thick tungsten film as the infrared heat sink for IPEB, the emitting uniformity of the electron source can be analyzed to evaluate the efficiency and stability of the diode system. Two-dimensional axisymmetric finite element method heat transfer simulation, combined with Monte Carlo calculation, was performed for error estimation and optimization of the method. The test of the method was finished with IPEB generated by explosive emission electron diode with pulse duration (FWHM) of 80 ns, electron energy up to 450 keV, and a total beam current of over 1 kA. The results showed that it is possible to measure the cross-sectional energy density distribution of IPEB with energy sensitivity of 0.1 J/cm(2) and spatial resolution of 1 mm. The technical details, such as irradiation protection of bremsstrahlung γ photons and the functional extensibility of the method were discussed in this work.

  19. Hemicrania Continua: Functional Imaging and Clinical Features With Diagnostic Implications.

    Science.gov (United States)

    Sahler, Kristen

    2013-04-10

    This review focuses on summarizing 2 pivotal articles in the clinical and pathophysiologic understanding of hemicrania continua (HC). The first article, a functional imaging project, identifies both the dorsal rostral pons (a region associated with the generation of migraines) and the posterior hypothalamus (a region associated with the generation of cluster and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing [SUNCT]) as active during HC. The second article is a summary of the clinical features seen in a prospective cohort of HC patients that carry significant diagnostic implications. In particular, they identify a wider range of autonomic signs than what is currently included in the International Headache Society criteria (including an absence of autonomic signs in a small percentage of patients), a high frequency of migrainous features, and the presence of aggravation and/or restlessness during attacks. Wide variations in exacerbation length, frequency, pain description, and pain location (including side-switching pain) are also noted. Thus, a case is made for widening and modifying the clinical diagnostic criteria used to identify patients with HC.

  20. Targeting SR-BI for cancer diagnostics, imaging and therapy

    Directory of Open Access Journals (Sweden)

    Maneesha Amrita Rajora

    2016-09-01

    Full Text Available Scavenger receptor class B type I (SR-BI plays an important role in trafficking cholesteryl esters between the core of high density lipoprotein and the liver. Interestingly, this integral membrane protein receptor is also implicated in the metabolism of cholesterol by cancer cells, whereby overexpression of SR-BI has been observed in a number of tumours and cancer cell lines, including breast and prostate cancers. Consequently, SR-BI has recently gained attention as a cancer biomarker and exciting target for the direct cytosolic delivery of therapeutic agents. This brief review highlights these key developments in SR-BI-targeted cancer therapies and imaging probes. Special attention is given to the exploration of high density lipoprotein nanomimetic platforms that take advantage of upregulated SR-BI expression to facilitate targeted drug-delivery and cancer diagnostics, and promising future directions in the development of these agents.

  1. First Steps Toward Incorporating Image Based Diagnostics Into Particle Accelerator Control Systems Using Convolutional Neural Networks

    OpenAIRE

    Edelen, A. L.; Biedron, S. G.; Milton, S. V.; Edelen, J. P.

    2016-01-01

    At present, a variety of image-based diagnostics are used in particle accelerator systems. Often times, these are viewed by a human operator who then makes appropriate adjustments to the machine. Given recent advances in using convolutional neural networks (CNNs) for image processing, it should be possible to use image diagnostics directly in control routines (NN-based or otherwise). This is especially appealing for non-intercepting diagnostics that could run continuously during beam operatio...

  2. Cost Of Managing Digital Diagnostic Images For A 614 Bed Hospital

    Science.gov (United States)

    Dwyer, Samuel J.; Templeton, Arch W.; Martin, Norman L.; Cook, Larry T.; Lee, Kyo R.; Levine, Errol; Batnitzky, Solomon; Preston, David F.; Rosenthal, Stanton J.; Price, Hilton I.; Anderson, William H.; Tarlton, Mark A.; Faszold, Susan

    1982-01-01

    The cost of recording and archiving digital diagnostic imaging data is presented for a Radiology Department serving a 614 bed University Hospital with a large outpatient population. Digital diagnostic imaging modalities include computed tomography, nuclear medicine, ultrasound, and digital radiography. The archiving media include multiformat video film recordings, magnetic tapes, and disc storage. The estimated cost per patient for the archiving of digital diagnostic imaging data is presented.

  3. Edge and Plasma -Wall Interaction Diagnostics in the TJ-II Stellarator

    Energy Technology Data Exchange (ETDEWEB)

    Tabares, F. L.; Tafalla, D.; Branas, B.; Hidalgo, A.; Garcia-Cortes, I.; Lopez-Fraguas, A.; Ortiz, P.

    2003-07-01

    The operation of the TJ-II stellarator, carried out under ECR heating conditions until now, the plasma edge parameters and those processes has been identified. Therefore, an important , has implieda careful control of partied e sources and the associated plasma-wall interaction processes. A clear coupling between the plasma edge parameters and those processes has been identified. Therefore, an important effort has been devoted to the development of dedicated diagnostics in both fields. Remarkable success has been attained in the development of atomic-beam based edge diagnostics, namely, thermal Li and supersonic He beams. In particular, fast (up to 200 Hz) sampling of temperature and density profiles has been made possible thorough an upgraded version of the pulsed, supersonic He beam diagnostic. In this paper, whorl devoted to the upgrading of these techniques is described. Also, preliminary experiments oriented to the validation of the collisional radiative models use din the beam-based diagnostic interpretaron as well as simulations of Laser Induced Fluorescence (LIF) studies of level populations of electronically excited He atoms are shown. (Author) 17 refs.

  4. Proceedings of the fifth Australia-Japan workshop on plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The fifth Australia-Japan Workshop on Plasma Diagnostics was held at Japan Atomic Energy Research Institute (JAERI), Naka, Japan, from December 15 to 17 in 1999. The first workshop was held at JAERI, Naka in 1989, and the workshops have been held almost every two years in Australia and Japan under the Agreement between the Government of Japan and the Government of Australia on cooperation in the field of Science and Technology. In the workshops, latest research works for plasma diagnostics and plasma experiment have been presented and discussed. The research works of both countries have been developed, and the mutual understanding became deeper through the workshops. In the fifth workshop, the statuses of JT-60U (JAERI), LHD (National Institute for Fusion Science) and H-1NF (Australian National University) were introduced, and the latest research works for plasma diagnostics were also presented. The active and deeper discussions were performed. This report contains twenty-eight papers presented at the workshop. The 25 of the presented papers are indexed individually. (J.P.N.)

  5. Diagnostic imaging of compression neuropathy; Bildgebende Diagnostik von Nervenkompressionssyndromen

    Energy Technology Data Exchange (ETDEWEB)

    Weishaupt, D.; Andreisek, G. [Universitaetsspital, Institut fuer Diagnostische Radiologie, Zuerich (Switzerland)

    2007-03-15

    Compression-induced neuropathy of peripheral nerves can cause severe pain of the foot and ankle. Early diagnosis is important to institute prompt treatment and to minimize potential injury. Although clinical examination combined with electrophysiological studies remain the cornerstone of the diagnostic work-up, in certain cases, imaging may provide key information with regard to the exact anatomic location of the lesion or aid in narrowing the differential diagnosis. In other patients with peripheral neuropathies of the foot and ankle, imaging may establish the etiology of the condition and provide information crucial for management and/or surgical planning. MR imaging and ultrasound provide direct visualization of the nerve and surrounding abnormalities. Bony abnormalities contributing to nerve compression are best assessed by radiographs and CT. Knowledge of the anatomy, the etiology, typical clinical findings, and imaging features of peripheral neuropathies affecting the peripheral nerves of the foot and ankle will allow for a more confident diagnosis. (orig.) [German] Kompressionsbedingte Schaedigungen peripherer Nerven koennen die Ursache hartnaeckiger Schmerzen im Bereich des Sprunggelenks und Fusses sein. Eine fruehzeitige Diagnose ist entscheidend, um den Patienten der richtigen Therapie zuzufuehren und potenzielle Schaedigungen zu vermeiden oder zu verringern. Obschon die klinische Untersuchung und die elektrophysiologische Abklaerungen die wichtigsten Elemente der Diagnostik peripherer Nervenkompressionssyndrome sind, kann die Bildgebung entscheidend sein, wenn es darum geht, die Hoehe des Nervenschadens festzulegen oder die Differenzialdiagnose einzugrenzen. In gewissen Faellen kann durch Bildgebung sogar die Ursache der Nervenkompression gefunden werden. In anderen Faellen ist die Bildgebung wichtig bei der Therapieplanung, insbesondere dann, wenn die Laesion chirurgisch angegangen wird. Magnetresonanztomographie (MRT) und Sonographie ermoeglichen eine

  6. Diagnostic imaging in child abuse; Bildgebende Diagnostik der Kindesmisshandlung

    Energy Technology Data Exchange (ETDEWEB)

    Stoever, B. [Charite, Campus Virchow-Klinikum, Universitaetsmedizin Berlin, Abteilung Paediatrische Radiologie, CC6, Diagnostische und interventionelle Radiologie und Nuklearmedizin, Berlin (Germany)

    2007-11-15

    Diagnostic imaging in child abuse plays an important role and includes the depiction of skeletal injuries, soft tissue lesions, visceral injuries in 'battered child syndrome' and brain injuries in 'shaken baby syndrome'. The use of appropriate imaging modalities allows specific fractures to be detected, skeletal lesions to be dated and the underlying mechanism of the lesion to be described. The imaging results must be taken into account when assessing the clinical history, clinical findings and differential diagnoses. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations must be performed in order to detect lesions of the central nervous system (CNS) immediately. CT is necessary in the initial diagnosis to delineate oedema and haemorrhages. Early detection of brain injuries in children with severe neurological symptoms can prevent serious late sequelae. MRI is performed in follow-up investigations and is used to describe residual lesions, including parenchymal findings. (orig.) [German] In der Diagnostik der Kindesmisshandlung ist die Bildgebung ein wesentlicher Faktor. Trotz scheinbar leerer Anamnese gelingt es, typische Verletzungsmuster als Misshandlungsfolge zu erkennen, sowohl im Bereich des Skeletts, der Weichteile, des Abdomens ('battered child syndrome', heute: 'non accidental injury', NAI) als auch im ZNS ('shaken baby syndrome'). Den klinischen Symptomen entsprechend, wird im Verdachtsfall ein adaequates diagnostisches Verfahren eingesetzt, das erwartete charakteristische Befunde nachweist, den Mechanismus der Verletzung aufzeigt und das Alter der Laesionen annaehernd festlegt. Radiologische Skelettbefunde werden hinsichtlich ihrer Spezifitaet fuer eine Misshandlung bewertet. Alle Resultate der Bildgebung sind zusammen mit Anamnese und klinischen Befunden zu deuten. Bei schwerer Misshandlung ohne aeussere Verletzungszeichen ist das rechtzeitige Erfassen einer ZNS

  7. Influence of plasma diagnostics and constraints on the quality of equilibrium reconstructions on Joint European Torus

    Energy Technology Data Exchange (ETDEWEB)

    Gelfusa, M.; Gaudio, P.; Peluso, E. [Associazione EURATOM-ENEA, University of Rome “Tor Vergata”, Roma (Italy); Murari, A.; Baruzzo, M. [Consorzio RFX-Associazione EURATOM ENEA per la Fusione, I-35127 Padova (Italy); Lupelli, I.; Hawkes, N.; Brix, M.; Drozdov, V.; Meigs, A.; Romanelli, M. [EURATOM/CCFE Fusion Association, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Craciunescu, T. [EURATOM-MEdC Association, NILPRP, Bucharest (Romania); Schmuck, S.; Sieglin, B. [Max-Planck-Institut für Plasmaphysik, Teilinstitut Greifswald, EURATOM Association, Wendelsteinstr.1, 17491 Greifswald (Germany); Collaboration: JET-EFDA Contributors

    2013-10-15

    One of the main approaches to thermonuclear fusion relies on confining high temperature plasmas with properly shaped magnetic fields. The determination of the magnetic topology is, therefore, essential for controlling the experiments and for achieving the required performance. In Tokamaks, the reconstruction of the fields is typically formulated as a free boundary equilibrium problem, described by the Grad-Shafranov equation in toroidal geometry and axisymmetric configurations. Unfortunately, this results in mathematically very ill posed problems and, therefore, the quality of the equilibrium reconstructions depends sensitively on the measurements used as inputs and on the imposed constraints. In this paper, it is shown how the different diagnostics (Magnetics Measurements, Polarimetry and Motional Stark Effect), together with the edge current density and plasma pressure constraints, can have a significant impact on the quality of the equilibrium on JET. Results show that both the Polarimetry and Motional Stark Effect internal diagnostics are crucial in order to obtain reasonable safety factor profiles. The impact of the edge current density constraint is significant when the plasma is in the H-mode of confinement. In this plasma scenario the strike point positions and the plasma last closed flux surface can change even by centimetres, depending on the edge constraints, with a significant impact on the remapping of the equilibrium-dependent diagnostics and of pedestal physics studies. On the other hand and quite counter intuitively, the pressure constraint can severely affect the quality of the magnetic reconstructions in the core. These trends have been verified with several JET discharges and consistent results have been found. An interpretation of these results, as interplay between degrees of freedom and available measurements, is provided. The systematic analysis described in the paper emphasizes the importance of having sufficient diagnostic inputs and of

  8. Additive manufacture (3d printing) of plasma diagnostic components and assemblies for fusion experiments

    Science.gov (United States)

    Sieck, Paul; Woodruff, Simon; Stuber, James; Romero-Talamas, Carlos; Rivera, William; You, Setthivoine; Card, Alexander

    2015-11-01

    Additive manufacturing (or 3D printing) is now becoming sufficiently accurate with a large range of materials for use in printing sensors needed universally in fusion energy research. Decreasing production cost and significantly lowering design time of energy subsystems would realize significant cost reduction for standard diagnostics commonly obtained through research grants. There is now a well-established set of plasma diagnostics, but these expensive since they are often highly complex and require customization, sometimes pace the project. Additive manufacturing (3D printing) is developing rapidly, including open source designs. Basic components can be printed for (in some cases) less than 1/100th costs of conventional manufacturing. We have examined the impact that AM can have on plasma diagnostic cost by taking 15 separate diagnostics through an engineering design using Conventional Manufacturing (CM) techniques to determine costs of components and labor costs associated with getting the diagnostic to work as intended. With that information in hand, we set about optimizing the design to exploit the benefits of AM. Work performed under DOE Contract DE-SC0011858.

  9. Construction, calibration, and application of a compact spectrophotometer for EUV (300-2500-A) plasma diagnostics.

    Science.gov (United States)

    Moos, H W; Chen, K I; Terry, J L; Fastie, W G

    1979-04-15

    A 400-mm normal incidence concave grating spectrophotometer, specifically designed for plasma diagnostics, is described. The wavelength drive, in which the grating is translated as well as rotated, is discussed in detail; the wavelength linearity of the sine drive and methods of improving it are analyzed. The instrument can be used in any orientation, is portable under vacuum, and quite rugged. The construction techniques utilized produce a high quality vacuum making the instrument compatible with both high purity plasma devices and synchrotron radiation sources. The photometric sensitivity calibration was found to be very stable during extended use on high temperature plasma devices. The applications of the instrument to diagnose plasmas in two tokamaks and a mirror device are described. A facility used for photometric calibration of extreme ultraviolet (lambda > 300-A) spectrophotometers against NBS standard diodes is described. The instrumental calibration obtained using this facility was checked by using synchrotron radiation from SURF II; very good agreement was observed.

  10. Optimization of the optical system for electron cyclotron emission imaging diagnostics on the HL-2A tokamak

    Science.gov (United States)

    Jiang, Min; Shi, Zhongbing; Zhu, Yilun

    2017-08-01

    The optical system of the electron cyclotron emission imaging diagnostics on the HL-2A tokamak has been optimized in both the narrow zoom pattern and the wide zoom pattern. The two main features of the improved optical system are (1) larger coverage of the measurement region in the plasma and (2) a flatter imaging surface. The new optics has good focal characteristics over the whole plasma cross section. The curvature of the field of the image surface (ΔR between the core channel and the edge channel) is within 5.3 cm in the narrow zoom pattern and 6.7 cm in the wide zoom pattern after optimization, whereas the values with the present optics were 23 cm in the narrow zoom pattern and 15 cm in the wide zoom pattern. The optics will be fabricated, tested and installed on the HL-2A tokamak before the next experimental campaign.

  11. Histological Image Feature Mining Reveals Emergent Diagnostic Properties for Renal Cancer.

    Science.gov (United States)

    Kothari, Sonal; Phan, John H; Young, Andrew N; Wang, May D

    2011-11-01

    Computer-aided histological image classification systems are important for making objective and timely cancer diagnostic decisions. These systems use combinations of image features that quantify a variety of image properties. Because researchers tend to validate their diagnostic systems on specific cancer endpoints, it is difficult to predict which image features will perform well given a new cancer endpoint. In this paper, we define a comprehensive set of common image features (consisting of 12 distinct feature subsets) that quantify a variety of image properties. We use a data-mining approach to determine which feature subsets and image properties emerge as part of an "optimal" diagnostic model when applied to specific cancer endpoints. Our goal is to assess the performance of such comprehensive image feature sets for application to a wide variety of diagnostic problems. We perform this study on 12 endpoints including 6 renal tumor subtype endpoints and 6 renal cancer grade endpoints. Keywords-histology, image mining, computer-aided diagnosis.

  12. Diagnostic performance of plasma mi-R499 for acute myocardial infarction

    Institute of Scientific and Technical Information of China (English)

    韩志君

    2014-01-01

    Objective To evaluate the diagnostic performance of plasma miR-499 in acute myocardial infarction(AMI)diagnosis.Methods Diagnostic accuracy test was used.The suspected AMI patients,who with chest pain for more than half an hour and been admitted in the SecondPeople’s Hospital of Wuxi and First People’s Hospital of Chuzhou during October 2010 and July 2011,were consecutively and prospectively enrolled in the present study.Sixty apparently healthy individuals were designed as healthy

  13. Neutral Beam Source and Target Plasma for Development of a Local Electric Field Fluctuation Diagnostic

    Science.gov (United States)

    Bakken, M. R.; Burke, M. G.; Fonck, R. J.; Lewicki, B. T.; Rhodes, A. T.; Winz, G. R.

    2016-10-01

    A new diagnostic measuring local E-> (r , t) fluctuations is being developed for plasma turbulence studies in tokamaks. This is accomplished by measuring fluctuations in the separation of the π components in the Hα motional Stark spectrum. Fluctuations in this separation are expected to be Ẽ / ẼEMSE 10-3EMSE 10-3 . In addition to a high throughput, high speed spectrometer, the project requires a low divergence (Ω 0 .5°) , 80 keV, 2.5 A H0 beam and a target plasma test stand. The beam employs a washer-stack arc ion source to achieve a high species fraction at full energy. Laboratory tests of the ion source demonstrate repeatable plasmas with Te 10 eV and ne 1.6 ×1017 m-3, sufficient for the beam ion optics requirements. Te and ne scalings of the ion source plasma are presented with respect to operational parameters. A novel three-phase resonant converter power supply will provide 6 mA/cm2 of 80 keV H0 at the focal plane for pulse lengths up to 15 ms, with low ripple δV / 80 keV 0.05 % at 280 kHz. Diagnostic development and validation tests will be performed on a magnetized plasma test stand with 0.5 T field. The test chamber will utilize a washer-stack arc source to produce a target plasma comparable to edge tokamak plasmas. A bias-plate with programmable power supply will be used to impose Ẽ within the target plasma. Work supported by US DOE Grant DE-FG02-89ER53296.

  14. Far infrared fusion plasma diagnostics. Task 3A, Progress report, FY 1990

    Energy Technology Data Exchange (ETDEWEB)

    Luhmann, N.C. Jr.; Peebles, W.A.

    1990-12-31

    Over the last several years, reflectometry has grown in importance as a diagnostic for both steady-state density Profiles as well as for the investigation of density fluctuations and turbulence. As a diagnostic for density profile measurement, it is generally believed to be well understood in the tokamak environment. However, its use as a fluctuation diagnostic is hampered by a lack of quantitative experimental understanding of its wavenumber sensitivity and spatial resolution. Several researchers, have theoretically investigated these questions. However, prior to the UCLA laboratory investigation, no group has experimentally investigated these questions. Because of the reflectometer`s importance to the world effort in understanding plasma turbulence and transport, UCLA has, over the last year, made its primary Task IIIA effort the resolution of these questions. UCLA has taken the lead in a quantitative experimental understanding of reflectometer data as applied to the measurement of density fluctuations. In addition to this, work has proceeded on the design, construction, and installation of a reflectometer system on UCLA`s CCT tokamak. This effort will allow a comparison between the improved confinement regimes (H-mode) observed on both the DIII-D and CCT machines with the goal of achieving a physics understanding of the phenomena. Preliminary investigation of a new diagnostic technique to measure density profiles as a function of time has been initiated at UCLA. The technique promises to be a valuable addition to the range of available plasma diagnostics. Work on advanced holographic reflectometry technique as applied to fluctuation diagnostics has awaited a better understanding of the reflectometer signal itself as discussed above. Efforts to ensure the transfer of the diagnostic developments have continued with particular attention devoted to the preliminary design of a multichannel FIR interferometer for MST.

  15. [Transparency regime: semiotics of radiographical images in urological diagnostics].

    Science.gov (United States)

    Martin, M; Fangerau, H

    2012-10-01

    Shortly after Röntgen discovered x-rays urology became one of the main test fields for the application of this new technology. Initial scepticism among physicians, who were inclined to cling to traditional manual methods of diagnosing, was replaced by enthusiasm for radiographic technologies and the new method soon became the standard in, for example the diagnosis of concrements. Patients favoring radiographic procedures over the use of probes and a convincing documentation of stones in radiograms were factors that impacted the relatively rapid integration of radiology into urology. The radiographic representation of soft tissues and body cavities was more difficult and the development of contrast agents in particular posed a serious problem. Several patients died during this research. A new diagnostic dimension was revealed when radiography and cystography were combined to form the method of retrograde pyelography. However, the problem of how urologists could learn how to read the new images remained. In order to allow trainee physicians to practice interpreting radiograms atlases were produced which offered explanatory texts and drawings for radiographic images of the kidneys, the bladder etc. Thus, urologists developed a self-contained semiotics which facilitated the appropriation of a unique urological radiographical gaze.

  16. PACS and diagnostic imaging service delivery-A UK perspective

    Energy Technology Data Exchange (ETDEWEB)

    Sutton, Laurence N., E-mail: lasusu@laurencesutton.co.uk [Diagnostic Imaging Department, Main X-Ray, Calderdale Royal Hospital, Calderdale and Huddersfield NHS Foundation Trust, Salterhebble, Halifax, West Yorkshire, HX3 0PW (United Kingdom)

    2011-05-15

    This review sets out the current position with regard to the implementation of PACS throughout the United Kingdom and the impact this has had on improving patient care. In December 2007 England had implemented full hospital-wide PACS in all hospitals: a major achievement in the relatively short time period of three years. The different approaches used by each country of the UK to achieve full national PACS are described in addition to the current issues with the sharing of images and reports across different healthcare organisations with regard to technical solutions, clinical safety and governance. The review gives insight into the changing methods of service delivery to address increasing demand pressures on diagnostic imaging services and how the national PACS implementation, specifically in England, has made a significant contribution to measures to improve efficiencies. The role of Teleradiology is discussed in the context of supporting local patient services rather than undermining them and the concept of cross-healthcare reporting 'Grids' is described. Finally, in the summary it is recognised that the vast wealth of knowledge accumulated during the national implementations has placed the UK in a strong position to facilitate full national data sharing across all healthcare organisations to improve patient care.

  17. Acoustic imaging for diagnostics of chemically reacting systems

    Science.gov (United States)

    Ramohalli, K.; Seshan, P.

    1983-01-01

    The concept of local diagnostics, in chemically reacting systems, with acoustic imaging is developed. The elements of acoustic imaging through ellipsoidal mirrors are theoretically discussed. In a general plan of the experimental program, the first system is chosen in these studies to be a simple open jet, non premixed turbulent flame. Methane is the fuel and enriched air is the oxidizer. This simple chemically reacting flow system is established at a Reynolds number (based on cold viscosity) of 50,000. A 1.5 m diameter high resolution acoustic mirror with an f-number of 0.75 is used to map the acoustic source zone along the axis of the flame. The results are presented as acoustic power spectra at various distances from the nozzle exit. It is seen that most of the reaction intensity is localized in a zone within 8 diameters from the exit. The bulk reactions (possibly around the periphery of the larger eddies) are evenly distributed along the length of the flame. Possibilities are seen for locally diagnosing single zones in a multiple cluster of reaction zones that occur frequently in practice. A brief outline is given of the future of this work which will be to apply this technique to chemically reacting flows not limited to combustion.

  18. Absolute calibration of space-resolving soft X-ray spectrograph for plasma diagnostics

    Science.gov (United States)

    Yoshikawa, M.; Okamoto, Y.; Kawamori, E.; Watanabe, Y.; Watabe, C.; Yamaguchi, N.; Tamano, T.

    2001-07-01

    A grazing incidence flat-field soft X-ray (20-350 Å) spectrograph was constructed and applied for impurity diagnostics in the GAMMA 10 fusion plasma. The spectrograph consisted of a limited height entrance slit, an aberration-corrected concave grating, a microchannel-plate intensified detector and an instant camera/a high speed solid state camera. An absolute calibration experiment for the SX spectrograph was performed at the Photon Factory in the High Energy Accelerator Research Organization with monitoring the incident synchrotron beam intensity by using an absolutely calibrated XUV silicon photodiode. From the results of absolute calibration of the spectrograph, the radiation loss from the plasma was obtained.

  19. Absolute calibration of space-resolving soft X-ray spectrograph for plasma diagnostics

    CERN Document Server

    Yoshikawa, M; Kawamori, E; Watanabe, Y; Watabe, C; Yamaguchi, N; Tamano, T

    2001-01-01

    A grazing incidence flat-field soft X-ray (20-350 A) spectrograph was constructed and applied for impurity diagnostics in the GAMMA 10 fusion plasma. The spectrograph consisted of a limited height entrance slit, an aberration-corrected concave grating, a microchannel-plate intensified detector and an instant camera/a high speed solid state camera. An absolute calibration experiment for the SX spectrograph was performed at the Photon Factory in the High Energy Accelerator Research Organization with monitoring the incident synchrotron beam intensity by using an absolutely calibrated XUV silicon photodiode. From the results of absolute calibration of the spectrograph, the radiation loss from the plasma was obtained.

  20. Formation of Imploding Plasma Liners for HEDP and MIF Applications - Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, Mark [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Electrical and Computer Engineering. Dept. of Physics and Astronomy; Hsu, Scott [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Witherspoon, F. Douglas [HyperV Technologies Corp., Chantilly, VA (United States); Cassibry, Jason [Univ. of Alabama, Huntsville, AL (United States); Bauer, Bruno S. [Univ. of Nevada, Reno, NV (United States)

    2015-04-27

    The goal of the plasma liner experiment (PLX) was to explore and demonstrate the feasibility of forming imploding spherical plasma liners that can reach High Energy Density (HED)-relevant (~ 0.1 Mbar) pressures upon stagnation. The plasma liners were to be formed by a spherical array of 30 – 36 railgun-driven hypervelocity plasma jets (Mach 10 – 50). Due to funding and project scope reductions in year two of the project, this initial goal was revised to focus on studies of individual jet propagation, and on two jet merging physics. PLX was a collaboration between a number of partners including Los Alamos National Laboratory, HyperV Technologies, University of New Mexico (UNM), University of Alabama, Huntsville, and University of Nevada, Reno. UNM’s part in the collaboration was primary responsibility for plasma diagnostics. Though full plasma liner experiments could not be performed, the results of single and two jet experiments nevertheless laid important groundwork for future plasma liner investigations. Though challenges were encountered, the results obtained with one and two jets were overwhelmingly positive from a liner formation point of view, and were largely in agreement with predictions of hydrodynamic models.

  1. Towards personalized diagnostics via longitudinal study of the human plasma N-glycome.

    Science.gov (United States)

    Hennig, René; Cajic, Samanta; Borowiak, Matthias; Hoffmann, Marcus; Kottler, Robert; Reichl, Udo; Rapp, Erdmann

    2016-08-01

    Facilitated by substantial advances in analytical methods, plasma N-glycans have emerged as potential candidates for biomarkers. In the recent years, several investigations could link aberrant plasma N-glycosylation to numerous diseases. However, due to often limited specificity and sensitivity, only a very limited number of glycan biomarkers were approved by the authorities up to now. The inter-individual heterogeneity of the plasma N-glycomes might mask disease related changes in conventional large cross-sectional cohort studies, with a one-time sampling approach. But, a possible benefit of longitudinal sampling in biomarker discovery could be, that already small changes during disease progression are revealed, by monitoring the plasma N-glycome of individuals over time. To evaluate this, we collected blood plasma samples of five healthy donors over a time period of up to six years (min. 1.5 years). The plasma N-glycome was analyzed by xCGE-LIF, to investigate the intra-individual N-glycome variability over time. It is shown, that the plasma N-glycome of an individual is remarkably stable over a period of several years, and that observed small longitudinal changes are independent from seasons, but significantly correlated with lifestyle and environmental factors. Thus, the potential of future longitudinal biomarker discovery studies could be demonstrated, which is a further step towards personalized diagnostics. This article is part of a Special Issue entitled "Glycans in personalised medicine" Guest Editor: Professor Gordan Lauc.

  2. Influence of electron injection into 27 cm audio plasma cell on the plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Haleem, N. A.; Ragheb, M. S.; Zakhary, S. G. [Accelerators Department, Nuclear Research Center, AEA, Cairo 13759 (Egypt); El Fiki, S. A.; Nouh, S. A. [Faculty of Science, Ain Shams University, Cairo 11566 (Egypt); El Disoki, T. M. [Faculty of Girls, Ain Shams University, Cairo 11566 (Egypt)

    2013-08-15

    In this article, the plasma is created in a Pyrex tube (L = 27 cm, φ= 4 cm) as a single cell, by a capacitive audio frequency (AF) discharge (f = 10–100 kHz), at a definite pressure of ∼0.2 Torr. A couple of tube linear and deviating arrangements show plasma characteristic conformity. The applied AF plasma and the injection of electrons into two gas mediums Ar and N{sub 2} revealed the increase of electron density at distinct tube regions by one order to attain 10{sup 13}/cm{sup 3}. The electrons temperature and density strengths are in contrast to each other. While their distributions differ along the plasma tube length, they show a decaying sinusoidal shape where their peaks position varies by the gas type. The electrons injection moderates electron temperature and expands their density. The later highest peak holds for the N{sub 2} gas, at electrons injection it changes to hold for the Ar. The sinusoidal decaying density behavior generates electric fields depending on the gas used and independent of tube geometry. The effect of the injected electrons performs a responsive impact on electrons density not attributed to the gas discharge. Analytical tools investigate the interaction of the plasma, the discharge current, and the gas used on the electrodes. It points to the emigration of atoms from each one but for greater majority they behave to a preferred direction. Meanwhile, only in the linear regime, small percentage of atoms still moves in reverse direction. Traces of gas atoms revealed on both electrodes due to sheath regions denote lack of their participation in the discharge current. In addition, atoms travel from one electrode to the other by overcoming the sheaths regions occurring transportation of particles agglomeration from one electrode to the other. The electrons injection has contributed to increase the plasma electron density peaks. These electrons populations have raised the generated electrostatic fields assisting the elemental ions

  3. Plasma globotriaosylsphingosine: diagnostic value and relation to clinical manifestations of Fabry disease.

    Science.gov (United States)

    Rombach, S M; Dekker, N; Bouwman, M G; Linthorst, G E; Zwinderman, A H; Wijburg, F A; Kuiper, S; Vd Bergh Weerman, M A; Groener, J E M; Poorthuis, B J; Hollak, C E M; Aerts, J M F G

    2010-09-01

    Fabry disease is an X-linked lysosomal storage disorder due to deficiency of alpha-Galactosidase A, causing accumulation of globotriaosylceramide and elevated plasma globotriaosylsphingosine (lysoGb3). The diagnostic value and clinical relevance of plasma lysoGb3 concentration was investigated. All male and adult female patients with classical Fabry disease could be discerned by an elevated plasma lysoGb3. In young pre-symptomatic Fabry heterozygotes, lysoGb3 levels can be normal. Individuals carrying the R112H and P60L mutations, without classical Fabry symptoms, showed no elevated plasma lysoGb3. Multiple regression analysis showed that there is no correlation of plasma lysoGb3 concentration with total disease severity score in Fabry males. However, plasma lysoGb3 concentration did correlate with white matter lesions (odds ratio: 6.1 per 100 nM lysoGb3 increase (95% CI: 1.4-25.9, p=0.015). In females, plasma lysoGb3 concentration correlated with overall disease severity. Furthermore, plasma lysoGb3 level was related to left ventricular mass (19.5+/-5.5 g increase per 10 nM lysoGb3 increase; p=0.001). In addition, it was assessed whether lifetime exposure to lysoGb3 correlates with disease manifestations. Male Fabry patients with a high lysoGb3 exposure (>10,000 U), were moderately or severely affected, only one mildly. Female patients with a low exposure (1000 U showed disease complications. Plasma lysoGb3 is useful for the diagnosis of Fabry disease. LysoGb3 is an independent risk factor for development of cerebrovascular white matter lesions in male patients and left ventricular hypertrophy in females. Disease severity correlates with exposure to plasma lysoGb3.

  4. Extreme ultraviolet and soft x-ray diagnostics of high-temperature plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Moos, W.

    1986-10-02

    This report describes recent progress and plans for calendar year 1987 in the Johns Hopkins University program to develop and improve spectroscopic diagnostics for the high temperature plasmas used in magnetic fusion research. An EUV spectrograph which provides time resolved spectra along fifteen chords of a plasma device has been completed and evaluation on DIII-D will began in late 1986. Other instrumentation work includes the evaluation of a sensitive detector for ion temperature/velocity distribution determinations and a feasibility study of Zeeman polarimetry for determining magnetic fields. A comprehensive data set taken on the TEXT tokamak is undergoing analysis as a means of improving the ionic parameters used in diagnostic studies and to expand the capabilities of existing instruments. Potential new advanced in spectroscopic technology are being monitored to determine if they provide advantages for fusion research.

  5. Extreme ultraviolet and soft x-ray diagnostics of high-temperature plasmas. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Moos, W.

    1986-10-02

    This report describes recent progress and plans for calendar year 1987 in the Johns Hopkins University program to develop and improve spectroscopic diagnostics for the high temperature plasmas used in magnetic fusion research. An EUV spectrograph which provides time resolved spectra along fifteen chords of a plasma device has been completed and evaluation on DIII-D will began in late 1986. Other instrumentation work includes the evaluation of a sensitive detector for ion temperature/velocity distribution determinations and a feasibility study of Zeeman polarimetry for determining magnetic fields. A comprehensive data set taken on the TEXT tokamak is undergoing analysis as a means of improving the ionic parameters used in diagnostic studies and to expand the capabilities of existing instruments. Potential new advanced in spectroscopic technology are being monitored to determine if they provide advantages for fusion research.

  6. Final Report - DOE Center for Laser Imaging and Cancer Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Alfano, Robert R.; Koutcher, Jason A.

    2002-10-31

    This Final Report summarizes the significant progress made by the researchers, students and staff of the Center for Laser Imaging and Cancer Diagnostics (CLICD) from January 1998 through May 2002. During this period, the Center supported several projects. Most projects were proposed initially, some were added subsequently as their relevance and importance to the DOE mission became evident. DOE support has been leveraged to obtain continuing funding for some projects. Leveraged funds come from various sources, including NIH, Army, NSF and the Air Force. The goal of the Center was to develop laser-based instruments for use in the detection and diagnosis of major diseases, with an emphasis on detection and diagnosis of various cancers. Each of the supported projects is a collaborative effort between physicists and laser scientists and the City College of New York and noted physicians, surgeons, pathologists, and biologists located at medical centers in the Metropolitan area. The participating institutions were: City College of New York Institute for Ultrafast Lasers and Spectroscopy, Hackensack University Medical Center, Lawrence Livermore National Laboratory, Memorial Sloan Kettering Cancer Center, and New York Eye and Ear Institute. Each of the projects funded by the Center is grouped into one of four research categories: a) Disease Detection, b) Non-Disease Applications, c) New Diagnostic Tools, and, d) Education, Training, Outreach and Dissemination. The progress achieved by the multidisciplinary teams was reported in 51 publications and 32 presentations at major national conferences. Also, one U.S. patent was obtained and six U.S. patent applications have been filed for innovations resulting from the projects sponsored by the Center.

  7. Diagnostic imaging of viral encephalitis; Bildgebende Diagnostik der Virusenzephalitiden

    Energy Technology Data Exchange (ETDEWEB)

    Weber, W.; Henkes, H.; Kuehne, D. [Alfried-Krupp-Krankenhaus Essen (Germany). Klinik fuer Radiologie und Neuroradiologie; Felber, S. [Universitaetsklinikum Innsbruck (Austria). Klinische Abt. der Radiologie I; Jaenisch, W. [Freie Univ. Berlin (Germany). Inst. fuer Neuropathologie; Schaper, J. [Klinikum der Univ. Essen (Germany). Zentralinst. fuer Radiologische Diagnostik

    2000-11-01

    The diagnostic procedure in viral encephalitis is based on the synopsis of clinical signs and symptoms, serological data, CSF analysis and diagnostic imaging findings. This article summarizes the findings of those viral encephalitides most frequently encountered in Western Europe. MRI is more sensitive than CT for the detection of inflammatory brain lesions due to the higher contrast resolution. The pattern of parenchymal damage is highly specific in only some viral encephalitides (e.g., the frequently hemorrhagic lesions of structures of the limbic system in herpes simples virus type I encephalitis; the symmetric and confluent lesions of the frontal white matter of progressive diffuse leukoencephalopathy in AIDS). In the majority of viral encephalitides MRI demonstrates the location and extension of parenchymal damage. The specific diagnosis in terms of the causative agent is based on serological studies. (orig.) [German] Die Diagnostik viraler Enzephalitiden basiert auf der synoptischen Auswertung klinischer, serologischer, liquoranalytischer und bildgebend erhobener Befunde. In der vorliegenden Arbeit werden die entsprechenden Befunde der haeufigsten in Westeuropa viral verursachten Enzephalitiden dargestellt. Generell ist bei entzuendlichen Laesionen des Hirnparenchyms die Kernspintomographie (MRT) aufgrund ihrer hohen Weichteilkontrastaufloesung der Computertomographie (CT) hinsichtlich der Nachweissensitivitaet ueberlegen. Bei einigen viralen Enzephalitiden ist das kernspintomographisch erfassbare Schaedigungsmuster hochspezifisch. Die gilt z.B. fuer die haeufig haemorrhagischen Laesionen der Strukturen des limbischen Systems bei der Herpes-simplex-Virus-Typ-1-Enzephalitis und fuer die flaechenhaft symmetrischen Marklagerlaesionen bei der progressiven diffusen Leukenzephalopathie bei AIDS-Patienten. Bei der Mehrzahl der viralen Enzephalitiden weist die MRT zwar die Lokalisation und Ausdehnung der Parenchymschaedigung nach, erlaubt jedoch keine sichere

  8. Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testing.

    Science.gov (United States)

    Yu, Stephanie C Y; Chan, K C Allen; Zheng, Yama W L; Jiang, Peiyong; Liao, Gary J W; Sun, Hao; Akolekar, Ranjit; Leung, Tak Y; Go, Attie T J I; van Vugt, John M G; Minekawa, Ryoko; Oudejans, Cees B M; Nicolaides, Kypros H; Chiu, Rossa W K; Lo, Y M Dennis

    2014-06-10

    Noninvasive prenatal testing using fetal DNA in maternal plasma is an actively researched area. The current generation of tests using massively parallel sequencing is based on counting plasma DNA sequences originating from different genomic regions. In this study, we explored a different approach that is based on the use of DNA fragment size as a diagnostic parameter. This approach is dependent on the fact that circulating fetal DNA molecules are generally shorter than the corresponding maternal DNA molecules. First, we performed plasma DNA size analysis using paired-end massively parallel sequencing and microchip-based capillary electrophoresis. We demonstrated that the fetal DNA fraction in maternal plasma could be deduced from the overall size distribution of maternal plasma DNA. The fetal DNA fraction is a critical parameter affecting the accuracy of noninvasive prenatal testing using maternal plasma DNA. Second, we showed that fetal chromosomal aneuploidy could be detected by observing an aberrant proportion of short fragments from an aneuploid chromosome in the paired-end sequencing data. Using this approach, we detected fetal trisomy 21 and trisomy 18 with 100% sensitivity (T21: 36/36; T18: 27/27) and 100% specificity (non-T21: 88/88; non-T18: 97/97). For trisomy 13, the sensitivity and specificity were 95.2% (20/21) and 99% (102/103), respectively. For monosomy X, the sensitivity and specificity were both 100% (10/10 and 8/8). Thus, this study establishes the principle of size-based molecular diagnostics using plasma DNA. This approach has potential applications beyond noninvasive prenatal testing to areas such as oncology and transplantation monitoring.

  9. High-pressure duo-multichannel soft x-ray spectrometer for tokamak plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Schwob, J.L.; Wouters, A.W.; Suckewer, S.

    1987-03-01

    A high-resolution, time-resolving soft X-ray multichannel spectrometer (SOXMOS) that permits the simultaneous measurement of emission in two different spectral ranges has been developed and tested extensively for tokamak plasma diagnostics. The basic instrument is a high-resolution, interferometrically adjusted, extreme grazing incidence Schwob-Fraenkel duochromator. The instrument is equipped with two multichannel detectors that are adjusted interferometrically and scan along the Rowland circle. Each consists of an MgF/sub 2/ coated, funneled microchannel plate, associated with a phosphor screen image intensifier that is coupled to a 1024-element photodiode array by a flexible fibrer optic conduit. The total wavelength coverage of the instrument is 5 to 340/sup 0/ A with a measured resolution (FWHM) of about 0.2 A when equipped with a 600 g/mm grating, and 5 to 85 A with a resolution of about 0.06 A using a 2400 g/mm grating. The simultaneous spectral coverage of each detector varies from 15 A at the short wavelength limit to 70 A at the long wavelength limit with the lower dispersion grating. The minimum read-out time for a full spectral portion is 17 ms, but several individual lines can be measured with 1 ms time resolution by selected pixel readout. Higher time resolution can be achieved by replacing one multichannel detector with a single channel electron multiplier detector. Examples of data from the PLT and TFTR tokamaks are presented to illustrate the instrument's versatility, high spectral resolution, and high signal-to-noise ratio even in the 10 A region. 44 refs., 20 figs.

  10. Serum lactate as predictor and diagnostic biomarker of plasma leakage in adult dengue patients

    Directory of Open Access Journals (Sweden)

    Rika Bur

    2016-12-01

    Full Text Available Background Dengue fever (DF and dengue hemorrhagic fever (DHF are differentiated by the occurrence in DHF of plasma leakage into the interstitial space as shown by pleural and peritoneal effusion, hemoconcentration, and intravascular hypovolemia. Perfusion dysfunction causes anaerobic metabolism, which leads to increased serum lactate. This study was to determine serum lactate as prognostic predictor and diagnostic biomarker of plasma leakage in adult dengue patients. Methods A cross-sectional retrospective cohort study was conducted on 57 adult dengue patients hospitalized in the internal medicine ward of Cipto Mangunkusumo Hospital and Persahabatan Hospital in Jakarta. Serum lactate was examined to determine its mean difference between DF and DHF. The data was analyzed by independent t-test and the cut-off points were identified for presence as well as absence of plasma leakage, then the receiver operating characteristics (ROC curve was used to determine sensitivity and specificity. Results Mean serum lactate was significantly higher in DHF than in DF. From the ROC curve, the cut-off point for serum lactate as prognostic predictor on day 3 of fever was ³2.65 mmol/L with AUC of 0.626 (95% CI 0.480-0.772; p=0.108. The cut-off point for diagnostic biomarker of plasma leakage on day 5 of fever was ³2.55 mmol/L with sensitivity 66.6%, specificity 54.2%, and AUC 0.668 (95% CI 0.550-0.826; p=0.016. Conclusion There was a significant difference in serum lactate between DF and DHF. In the critical phase, serum lactate of ³2.55 mmol/L could be used as plasma leakage diagnostic marker of low accuracy.

  11. Modeling and Simulation for Nanoparticle Plasma Jet Diagnostic Probe for Runaway Electron Beam-Plasma Interaction

    Science.gov (United States)

    Bogatu, I. N.; Galkin, S. A.

    2016-10-01

    The C60 nanoparticle plasma jet (NPPJ) rapid injection into a tokamak major disruption is followed by C60 gradual fragmentation along plasma-traversing path. The result is abundant C ion concentration in the core plasma enhancing the potential to probe and diagnose the runaway electrons (REs) during different phases of their dynamics. A C60/C NPPJ of 75 mg, high-density (>1023 m-3) , hyper-velocity (>4 km/s), and uniquely fast response-to-delivery time ( 1 ms) has been demonstrated on a test bed. It can rapidly and deeply deliver enough mass to increase electron density to 2.4x1021 m-3, 60 times larger than typical DIII-D pre-disruption value. We will present the results of our on-going work on: 1) self-consistent model for RE current density evolution (by Dreicer mechanism and ``avalanche'') focused on the effect of fast and deep deposition of C ions, 2) improvement of single C60q+ fragmenting ion penetration model through tokamak B(R)-field and post-TQ plasma, and 3) simulation of C60q+ PJ penetration through the DIII-D characteristic 2 T B-field to the RE beam central location by using the Hybrid Electro-Magnetic 2D code (HEM-2D. Work supported by US DOE DE-SC0015776 Grant.

  12. Optimization of diagnostic imaging use in patients with acute abdominal pain (OPTIMA): Design and rationale

    OpenAIRE

    Bossuyt Patrick MM; Dijkgraaf Marcel GW; van Randen Adrienne; Laméris Wytze; Stoker Jaap; Boermeester Marja A

    2007-01-01

    Abstract Background The acute abdomen is a frequent entity at the Emergency Department (ED), which usually needs rapid and accurate diagnostic work-up. Diagnostic work-up with imaging can consist of plain X-ray, ultrasonography (US), computed tomography (CT) and even diagnostic laparoscopy. However, no evidence-based guidelines exist in current literature. The actual diagnostic work-up of a patient with acute abdominal pain presenting to the ED varies greatly between hospitals and physicians....

  13. Study design for concurrent development, assessment, and implementation of new diagnostic imaging technology

    NARCIS (Netherlands)

    M.G.M. Hunink (Myriam); G.P. Krestin (Gabriel)

    2002-01-01

    textabstractWith current constraints on health care resources and emphasis on value for money, new diagnostic imaging technologies must be assessed and their value demonstrated. The state of the art in the field of diagnostic imaging technology assessment advocates a hierarchical

  14. Limited Diagnostic Utility of Plasma Adrenocorticotropic Hormone for Differentiation between Adrenal Cushing Syndrome and Cushing Disease.

    Science.gov (United States)

    Hong, A Ram; Kim, Jung Hee; Hong, Eun Shil; Kim, I Kyeong; Park, Kyeong Seon; Ahn, Chang Ho; Kim, Sang Wan; Shin, Chan Soo; Kim, Seong Yeon

    2015-09-01

    Measurement of the plasma adrenocorticotropic hormone (ACTH) level has been recommended as the first diagnostic test for differentiating between ACTH-independent Cushing syndrome (CS) and ACTH-dependent CS. When plasma ACTH values are inconclusive, a differential diagnosis of CS can be made based upon measurement of the serum dehydroepiandrosterone sulfate (DHEA-S) level and results of the high-dose dexamethasone suppression test (HDST). The aim of this study was to assess the utility of plasma ACTH to differentiate adrenal CS from Cushing' disease (CD) and compare it with that of the HDST results and serum DHEA-S level. We performed a retrospective, multicenter study from January 2000 to May 2012 involving 92 patients with endogenous CS. The levels of plasma ACTH, serum cortisol, 24-hour urine free cortisol (UFC) after the HDST, and serum DHEA-S were measured. Fifty-seven patients had adrenal CS and 35 patients had CD. The area under the curve of plasma ACTH, serum DHEA-S, percentage suppression of serum cortisol, and UFC after HDST were 0.954, 0.841, 0.950, and 0.997, respectively (all P<0.001). The cut-off values for plasma ACTH, percentage suppression of serum cortisol, and UFC after HDST were 5.3 pmol/L, 33.3%, and 61.6%, respectively. The sensitivity and specificity of plasma ACTH measurement were 84.2% and 94.3%, those of serum cortisol were 95.8% and 90.6%, and those of UFC after the HDST were 97.9% and 96.7%, respectively. Significant overlap in plasma ACTH levels was seen between patients with adrenal CS and those with CD. The HDST may be useful in differentiating between these forms of the disease, especially when the plasma ACTH level alone is not conclusive.

  15. [Two-temperature diagnostic studies by emission spectra for nonequilibrium Ti-H plasma].

    Science.gov (United States)

    Deng, Chun-feng; Lu, Biao; Wu, Chun-lei; Wang, Yi-fu; Wen, Zhong-wei

    2014-12-01

    Using the T-H solid solution made by titanium absorbed hydrogen as the cathode, the Ti-H plasma produced by the pulsed vacuum are ion source was nonequilibrium: it contained both the component of titanium and hydrogen; there existed gradient in the radiaL, the horizontal and the time. As a result, it could not be described by a single temperature. The present paper assumed that the subsystem consisting of electrons and the subsystem consisting of other heavy particles reached equilibrium respectively, meaning that the Ti-H plasma was described by the two temperatures as electron temperature and heavy ion temperature, it was non-equilibrium two-temperature plasma Using Culdberg-Waage dissociation equation to describe the molecular dissociation process in the system, using Saha ionization equation to describe the atomic ionization process, combining plasma's charge quasi-neutral condition and introducing atomic emission spectroscopy as a plasma diagnostic method which would not interfere the plasma at the same time; the temperature and the particle number density of the Ti-H plasma were diagnosed. Using MATLAB as a tool, both the titanium atoms and monovalent titanium ions' ionization were considered, and the calculated results showed that with the electtron density determined by the Stark broadening of spectral lines in advance, except the heavy particle temperature and the hydrogen number density, the Ti-H plasma's parameters could be diagnosed fairly accurately; the accuracy of the electron density values had a great effect on the calculation results; if the heavy particle temperature could be determined in advance, the temperature and the particle number density of the Ti-H plasma could be accurately analyzed quantitatively.

  16. He-like ions as practical astrophysical plasma diagnostics: From stellar coronae to active galactic nuclei

    CERN Document Server

    Porquet, Delphine; Grosso, Nicolas; 10.1007/s11214-010-9731-2

    2011-01-01

    We review X-ray plasma diagnostics based on the line ratios of He-like ions. Triplet/singlet line intensities can be used to determine electronic temperature and density, and were first developed for the study of the solar corona. Since the launches of the X-ray satellites Chandra and XMM-Newton, these diagnostics have been extended and used (from CV to Si XIII) for a wide variety of astrophysical plasmas such as stellar coronae, supernova remnants, solar system objects, active galactic nuclei, and X-ray binaries. Moreover, the intensities of He-like ions can be used to determine the ionization process(es) at work, as well as the distance between the X-ray plasma and the UV emission source for example in hot stars. In the near future thanks to the next generation of X-ray satellites (e.g., Astro-H and IXO), higher-Z He-like lines (e.g., iron) will be resolved, allowing plasmas with higher temperatures and densities to be probed. Moreover, the so-called satellite lines that are formed closed to parent He-like ...

  17. Development of simple designs of multitip probe diagnostic systems for RF plasma characterization.

    Science.gov (United States)

    Naz, M Y; Shukrullah, S; Ghaffar, A; Rehman, N U

    2014-01-01

    Multitip probes are very useful diagnostics for analyzing and controlling the physical phenomena occurring in low temperature discharge plasmas. However, DC biased probes often fail to perform well in processing plasmas. The objective of the work was to deduce simple designs of DC biased multitip probes for parametric study of radio frequency plasmas. For this purpose, symmetric double probe, asymmetric double probe, and symmetric triple probe diagnostic systems and their driving circuits were designed and tested in an inductively coupled plasma (ICP) generated by a 13.56 MHz radio frequency (RF) source. Using I-V characteristics of these probes, electron temperature, electron number density, and ion saturation current was measured as a function of input power and filling gas pressure. An increasing trend was noticed in electron temperature and electron number density for increasing input RF power whilst a decreasing trend was evident in these parameters when measured against filling gas pressure. In addition, the electron energy probability function (EEPF) was also studied by using an asymmetric double probe. These studies confirmed the non-Maxwellian nature of the EEPF and the presence of two groups of the energetic electrons at low filling gas pressures.

  18. Development of Simple Designs of Multitip Probe Diagnostic Systems for RF Plasma Characterization

    Directory of Open Access Journals (Sweden)

    M. Y. Naz

    2014-01-01

    Full Text Available Multitip probes are very useful diagnostics for analyzing and controlling the physical phenomena occurring in low temperature discharge plasmas. However, DC biased probes often fail to perform well in processing plasmas. The objective of the work was to deduce simple designs of DC biased multitip probes for parametric study of radio frequency plasmas. For this purpose, symmetric double probe, asymmetric double probe, and symmetric triple probe diagnostic systems and their driving circuits were designed and tested in an inductively coupled plasma (ICP generated by a 13.56 MHz radio frequency (RF source. Using I-V characteristics of these probes, electron temperature, electron number density, and ion saturation current was measured as a function of input power and filling gas pressure. An increasing trend was noticed in electron temperature and electron number density for increasing input RF power whilst a decreasing trend was evident in these parameters when measured against filling gas pressure. In addition, the electron energy probability function (EEPF was also studied by using an asymmetric double probe. These studies confirmed the non-Maxwellian nature of the EEPF and the presence of two groups of the energetic electrons at low filling gas pressures.

  19. Collisional-radiative modelling for the spectroscopic diagnostic of turbulent plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Rosato, J.; Lefevre, T.; Escarguel, A.; Capes, H.; Catoire, F.; Marandet, Y.; Stamm, R. [PIIM, Universite de Provence, CNRS, Marseille (France); Rosmej, F.B. [Universite Pierre et Marie Curie, Paris (France)] [LULI, Palaiseau (France); Kadomtsev, M.B.; Levashova, M.G.; Lisitsa, V.S. [NFI, Russian Research Center, Kurchatov Institute, Moscow (Russian Federation); Bonhomme, G. [IJL, Universite de Nancy, CNRS, Vandoeuvre-les-Nancy (France)

    2011-07-01

    Spectroscopy is a diagnostic method widely used in plasma physics research, e.g. in laboratory experiments, in fusion devices or in astrophysics. Information on the plasma parameters (electron density, temperature etc.) can be obtained from the analysis of both line shapes and intensities through the use of suitable models. The aim of the present paper is to assess the role of turbulent fluctuations on line intensity ratios in the case of weakly radiating plasmas. This involves the use of collisional-radiative modelling. In the present work we address the radiation due to atomic lines in turbulent helium plasmas at low density/temperature. The statistical formalism previously used in line shape modelling is adapted in this way, and the atomic populations are calculated with a collisional-radiative code. Different regimes, according to the turbulence correlation time, have been considered. In the static case, which corresponds to low-frequency fluctuations, it has been shown that the turbulence can lead to an increase of the line intensities. An application to helium in realistic experimental conditions has revealed that line ratios are sensitive to the fluctuations, which offers a track to a diagnostic. In the dynamic case, the use of a reduced model in the case of an ideal two-level atom has revealed the possibility for a significant dependence of the atomic populations on the turbulence frequency

  20. Diagnostics of recombining laser plasma parameters based on He-like ion resonance lines intensity ratios

    Science.gov (United States)

    Ryazantsev, S. N.; Skobelev, I. Yu; Faenov, A. Ya; Pikuz, T. A.; Grum-Grzhimailo, A. N.; Pikuz, S. A.

    2016-11-01

    While the plasma created by powerful laser expands from the target surface it becomes overcooled, i.e. recombining one. Improving of diagnostic methods applicable for such plasma is rather important problem in laboratory astrophysics nowadays because laser produced jets are fully scalable to young stellar objects. Such scaling is possible because of the plasma hydrodynamic equations invariance under some transformations. In this paper it is shown that relative intensities of the resonance transitions in He-like ions can be used to measure the parameters of recombining plasma. Intensity of the spectral lines corresponding to these transitions is sensitive to the density in the range of 1016-1020 cm-3 while the temperature ranges from 10 to 100 eV for ions with nuclear charge Zn ∼ 10. Calculations were carried out for F VIII ion and allowed to determine parameters of plasma jets created by nanosecond laser system ELFIE (Ecole Polytechnique, France) for astrophysical phenomenon modelling. Obtained dependencies are quite universal and can be used for any recombining plasma containing He-like fluorine ions.

  1. PIC Simulation of RF Plasma Sheath Formation and Initial Validation of Optical Diagnostics using HPC Resources

    Science.gov (United States)

    Icenhour, Casey; Exum, Ashe; Martin, Elijah; Green, David; Smithe, David; Shannon, Steven

    2014-10-01

    The coupling of experiment and simulation to elucidate near field physics above ICRF antennae presents challenges on both the experimental and computational side. In order to analyze this region, a new optical diagnostic utilizing active and passive spectroscopy is used to determine the structure of the electric fields within the sheath region. Parallel and perpendicular magnetic fields with respect to the sheath electric field have been presented. This work focuses on the validation of these measurements utilizing the Particle-in-Cell (PIC) simulation method in conjunction with High Performance Computing (HPC) resources on the Titan supercomputer at Oak Ridge National Laboratory (ORNL). Plasma parameters of interest include electron density, electron temperature, plasma potentials, and RF plasma sheath voltages and thicknesses. The plasma is modeled utilizing the VSim plasma simulation tool, developed by the Tech-X Corporation. The implementation used here is a two-dimensional electromagnetic model of the experimental setup. The overall goal of this study is to develop models for complex RF plasma systems and to help outline the physics of RF sheath formation and subsequent power loss on ICRF antennas in systems such as ITER. This work is carried out with the support of Oak Ridge National Laboratory and the Tech-X Corporation.

  2. Reconstruction of quasi-monochromatic images from a multiple monochromatic x-ray imaging diagnostic for inertial confinement fusion

    Energy Technology Data Exchange (ETDEWEB)

    Izumi, N; Turner, R; Barbee, T; Koch, J; Welser, L; Mansini, R

    2004-04-15

    We have developed a software package for image reconstruction of a multiple monochromatic x-ray imaging diagnostics (MMI) for diagnostic of inertial conferment fusion capsules. The MMI consists of a pinhole array, a multi-layer Bragg mirror, and a charge injection device image detector (CID). The pinhole array projects {approx}500 sub-images onto the CID after reflection off the multi-layer Bragg mirror. The obtained raw images have continuum spectral dispersion on its vertical axis. For systematic analysis, a computer-aided reconstruction of the quasi-monochromatic image is essential.

  3. Contribution of satellite lines to temperature diagnostics with He-like triplet lines in photoionized plasma

    Science.gov (United States)

    Wang, Feilu; Han, Bo; Salzmann, David; Zhao, Gang

    2017-04-01

    In the present paper, the He α triplet line ratios (resonance, intercombination, and forbidden lines) are computed for photoionized plasmas, when the contributions of nearby satellite lines are taken into account. The computations have been carried out with our radiative-collisional code, RCF, which is based on the flexible atomic code. The calculations of these line ratios have been done for three materials, namely, silicon, magnesium, and neon. Our calculations are used to derive the plasma temperatures for several astronomical objects, where the spectra are emitted from photoionizing plasmas. It is shown that the incorporation of the satellite lines from doubly excited Li-like ions into the He α triplet lines is necessary to obtain reliable temperature diagnostics for these astrophysical objects.

  4. Plasma DNA integrity index as a potential molecular diagnostic marker for breast cancer.

    Science.gov (United States)

    Kamel, Azza M; Teama, Salwa; Fawzy, Amal; El Deftar, Mervat

    2016-06-01

    Plasma DNA integrity index is increased in various malignancies including breast cancer, the most common cancer in women worldwide; early detection is crucial for successful treatment. Current screening methods fail to detect many cases of breast cancer at an early stage. In this study, we evaluated the level of plasma DNA integrity index in 260 females (95 with breast cancer, 95 with benign breast lesions, and 70 healthy controls) to verify its potential value in discriminating malignant from benign breast lesions. The criteria of the American Joint Committee on Cancer were used for staging of breast cancer patients. DNA integrity index was measured by real-time PCR. DNA integrity index was significantly higher in breast cancer than in benign breast patients and healthy subjects (P = cancer group was 85.3 % at 0.55 DNA integrity index cutoff. In conclusion, the plasma DNA integrity index may be a promising molecular diagnostic marker of malignancy in breast lesions.

  5. Investigation of the possibility of gamma-ray diagnostic imaging of target compression at NIF.

    Science.gov (United States)

    Lemieux, Daniel A; Baudet, Camille; Grim, Gary P; Barber, H Bradford; Miller, Brian W; Fasje, David; Furenlid, Lars R

    2011-09-23

    The National Ignition Facility at Lawrence Livermore National Laboratory is the world's leading facility to study the physics of igniting plasmas. Plasmas of hot deuterium and tritium, undergo d(t,n)α reactions that produce a 14.1 MeV neutron and 3.5 MeV a particle, in the center of mass. As these neutrons pass through the materials surrounding the hot core, they may undergo subsequent (n,x) reactions. For example, (12)C(n,n'γ)(12)C reactions occur in remnant debris from the polymer ablator resulting in a significant fluence of 4.44 MeV gamma-rays. Imaging of these gammas will enable the determination of the volumetric size and symmetry of the ablation; large size and high asymmetry is expected to correlate with poor compression and lower fusion yield. Results from a gamma-ray imaging system are expected to be complimentary to a neutron imaging diagnostic system already in place at the NIF. This paper describes initial efforts to design a gamma-ray imaging system for the NIF using the existing neutron imaging system as a baseline for study. Due to the cross-section and expected range of ablator areal densities, the gamma flux should be approximately 10(-3) of the neutron flux. For this reason, care must be taken to maximize the efficiency of the gamma-ray imaging system because it will be gamma starved. As with the neutron imager, use of pinholes and/or coded apertures are anticipated. Along with aperture and detector design, the selection of an appropriate scintillator is discussed. The volume of energy deposition of the interacting 4.44 MeV gamma-rays is a critical parameter limiting the imaging system spatial resolution. The volume of energy deposition is simulated with GEANT4, and plans to measure the volume of energy deposition experimentally are described. Results of tests on a pixellated LYSO scintillator are also presented.

  6. Temperature diagnostics of a non-thermal plasma jet at atmospheric pressure

    Science.gov (United States)

    Schäfer, Jan

    2013-09-01

    The study reflects the concept of the temperature as a physical quantity resulting from the second thermodynamic law. The reliability of different approaches of the temperature diagnostics of open non-equilibrium systems is discussed using examples of low temperature atmospheric pressure discharges. The focus of this work is a miniaturized non-thermal atmospheric pressure plasma jet for local surface treatment at ambient atmosphere. The micro-discharge is driven with a capacitively coupled radio frequency electric field at 27.12 MHz and fed with argon at rates of about 1 slm through the capillary with an inner diameter of 4 mm. The discharge consists of several contracted filaments with diameter around 300 μm which are rotating azimuthally in the capillary in a self-organized manner. While the measured temperatures of the filament core exceed 700 K, the heat impact on a target below the plasma jet remains limited leading to target temperatures below 400 K. Different kinds of temperatures and energy transport processes are proposed and experimentally investigated. Nevertheless, a reliable and detailed temperature diagnostics is a challenge. We report on a novel diagnostics approach for the spatially and temporally resolved measurement of the gas temperature based on the optical properties of the plasma. Laser Schlieren Deflectometry is adapted to explore temperature profiles of filaments and their behaviour. In parallel, the method demonstrates a fundamental Fermat's principle of minimal energy. Information acquired with this method plays an important role for the optimization of local thin film deposition and surface functionalization by means of the atmospheric pressure plasma jet. The work was supported in part by the Deutsche Forschungsgemeinschaft within SFB-TR 24.

  7. 13th TOPICAL CONFERENCE ON HIGH TEMPERATURE PLASMA DIAGNOSTICS SCIENTIFIC PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    C. BARNES

    2000-07-01

    Electron cyclotron emission (ECE) has been employed as a standard electron temperature profile diagnostic on many tokamaks and stellarators, but most magnetically confined plasma devices cannot take advantage of standard ECE diagnostics to measure temperature. They are either overdense, operating at high density relative to the magnetic field (e.g. {omega}{sub pe} >> {Omega}{sub ce} in a spherical torus) or they have insufficient density and temperature to reach the blackbody condition ({tau} > 2). Electron Bernstein waves (EBWs) are electrostatic waves which can propagate in overdense plasmas and have a high optical thickness at the electron cyclotron resonance layers, as a result of their large K{sub i}. This talk reports on measurements of EBW emission on the CDX-U spherical torus, where B{sub 0} {approx} 2 kG, {approx} 10{sup 13} cm{sup -3} and T{sub e} {approx} 10 - 200 eV. Results will be presented for both direct detection of EBWs and for mode-converted EBW emission. The EBW emission was absolutely calibrated and compared to the electron temperature profile measured by a multi-point Thomson scattering diagnostic. Depending on the plasma conditions, the mode-converted EBW radiation temperature was found to be {le} T{sub e} and the emission source was determined to be radially localized at the electron cyclotron resonance layer. A Langmuir triple probe was employed to measure changes in edge density profile in the vicinity of the upper hybrid resonance where the mode conversion of the EBWs is expected to occur. Changes in the mode conversion efficiency may explain the observation of mode-converted EBW radiation temperatures below T{sub e}. Initial results suggest EBW emission and EBW heating are viable concepts for plasmas where {omega}{sub pe} >> {Omega}{sub ce}.

  8. Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study

    Science.gov (United States)

    Zalev, Jason; Clingman, Bryan; Herzog, Don; Miller, Tom; Ulissey, Michael; Stavros, A. T.; Oraevsky, Alexander; Lavin, Philip; Kist, Kenneth; Dornbluth, N. C.; Otto, Pamela

    2015-03-01

    Functional opto-acoustic (OA) imaging was fused with gray-scale ultrasound acquired using a specialized duplex handheld probe. Feasibility Study findings indicated the potential to more accurately characterize breast masses for cancer than conventional diagnostic ultrasound (CDU). The Feasibility Study included OA imagery of 74 breast masses that were collected using the investigational Imagio® breast imaging system. Superior specificity and equal sensitivity to CDU was demonstrated, suggesting that OA fusion imaging may potentially obviate the need for negative biopsies without missing cancers in a certain percentage of breast masses. Preliminary results from a 100 subject Pilot Study are also discussed. A larger Pivotal Study (n=2,097 subjects) is underway to confirm the Feasibility Study and Pilot Study findings.

  9. NMR imaging of the liver. Diagnostics, differential diagnostics, therapeutic approaches; MRT der Leber. Diagnostik, Differenzialdiagnostik, Therapieansaetze

    Energy Technology Data Exchange (ETDEWEB)

    Fischbach, Frank; Fischbach, Katharina [Universitaetsklinikum Magdeburg A.oe.R. (Germany). Klinik fuer Radiologie und Nuklearmedizin

    2017-03-01

    The book on NMR imaging of the liver covers the following issues: Fundamentals of NMR imaging, T1-weighted imaging; T2-weighted imaging, diffusion-weighted imaging, cavernous hemangioma, focal nodular hyperplasy; hepatocellular adenoma, hepatocellulas carcinoma, cholangiocellular carcinoma, hepatic metastases.

  10. Enhancement of space plasma images by complex wavelets

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Vitor Moura; Domingues, Margarete Oliveira; Mendes, Odim, E-mail: vitor.souza@inpe.br [Instituto Nacional de Pesquisas Espaciais (INPE), Sao Jose dos Campos, SP (Brazil); Pagamisse, Aylton [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Presidente Prudente, SP (Brazil). Fav. de Ciencias e Tecnologia; Stenborg, Guilhermo Adrian [College of Science, George Mason University, Fairfax, VA (United States)

    2015-10-15

    The Sun is a natural laboratory for plasma processes. A myriad of instruments aboard satellites and on ground record(ed) the plasma emission in different ranges of the electromagnetic spectrum to help understand such processes. In particular, in the outer part of the solar atmosphere, the solar corona, we can observe a multitude of electrodynamical phenomena. There, the faint corona emission and the associated dynamic plasma structures (e.g., coronal mass ejections - CMEs) recorded in white light images can be used as basis for some insight of this physical scenario. In order to characterize the dynamics and morphology of such structures in a better way, it seems crucial that some features of those images should be enhanced. To deal with this need, a new approach using a complex wavelet transform methodology was developed. With the proposed methodology, we can highlight the plasma ejections improving the identification of those structures. (author)

  11. Hybrid-structure atomic models for HED laboratory plasma diagnostics and simulations

    Science.gov (United States)

    Hansen, Stephanie

    2010-03-01

    While theoretical atomic physics calculations are well developed for isolated atoms and have been thoroughly benchmarked against low-density laboratory sources such as electron beam ion traps and tokamak plasmas, the high energy density (HED) regime offers significant challenges for atomic physics and spectroscopic modeling. High plasma densities lead to collective effects such as continuum lowering, line broadening, and significant populations in multiply excited atomic states. These effects change the plasma equation of state and the character of emission and absorption spectra and must be accounted for in order to accurately simulate radiative transfer in and apply spectroscopic diagnostics to HED plasmas. Modeling complex mid- and high-Z ions in the HED regime is a particular challenge because exponential growth in accessible configuration space overwhelms the reduction of the Rydberg levels through continuum lowering. This talk will discuss one approach to generating a tractable spectroscopic-quality atomic kinetics model and describe its application to HED laboratory plasmas produced on Sandia's Z facility. [4pt] Sandia is a multi-program laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  12. Plasma Distribution in Mercury's Magnetosphere Derived from MESSENGER Magnetometer and Fast Imaging Plasma Spectrometer Observations

    Science.gov (United States)

    Korth, Haje; Anderson, Brian J.; Gershman, Daniel J.; Raines, Jim M.; Slavin, James A.; Zurbuchen, Thomas H.; Solomon, Sean C.; McNutt, Ralph L.

    2014-01-01

    We assess the statistical spatial distribution of plasma in Mercury's magnetosphere from observations of magnetic pressure deficits and plasma characteristics by the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft. The statistical distributions of proton flux and pressure were derived from 10months of Fast Imaging Plasma Spectrometer (FIPS) observations obtained during the orbital phase of the MESSENGER mission. The Magnetometer-derived pressure distributions compare favorably with those deduced from the FIPS observations at locations where depressions in the magnetic field associated with the presence of enhanced plasma pressures are discernible in the Magnetometer data. The magnitudes of the magnetic pressure deficit and the plasma pressure agree on average, although the two measures of plasma pressure may deviate for individual events by as much as a factor of approximately 3. The FIPS distributions provide better statistics in regions where the plasma is more tenuous and reveal an enhanced plasma population near the magnetopause flanks resulting from direct entry of magnetosheath plasma into the low-latitude boundary layer of the magnetosphere. The plasma observations also exhibit a pronounced north-south asymmetry on the nightside, with markedly lower fluxes at low altitudes in the northern hemisphere than at higher altitudes in the south on the same field line. This asymmetry is consistent with particle loss to the southern hemisphere surface during bounce motion in Mercury's offset dipole magnetic field.

  13. Talbot-Lau x-ray deflectometer electron density diagnostic for laser and pulsed power high energy density plasma experiments (invited)

    Science.gov (United States)

    Valdivia, M. P.; Stutman, D.; Stoeckl, C.; Mileham, C.; Begishev, I. A.; Theobald, W.; Bromage, J.; Regan, S. P.; Klein, S. R.; Muñoz-Cordovez, G.; Vescovi, M.; Valenzuela-Villaseca, V.; Veloso, F.

    2016-11-01

    Talbot-Lau X-ray deflectometry (TXD) has been developed as an electron density diagnostic for High Energy Density (HED) plasmas. The technique can deliver x-ray refraction, attenuation, elemental composition, and scatter information from a single Moiré image. An 8 keV Talbot-Lau interferometer was deployed using laser and x-pinch backlighters. Grating survival and electron density mapping were demonstrated for 25-29 J, 8-30 ps laser pulses using copper foil targets. Moiré pattern formation and grating survival were also observed using a copper x-pinch driven at 400 kA, ˜1 kA/ns. These results demonstrate the potential of TXD as an electron density diagnostic for HED plasmas.

  14. Talbot-Lau x-ray deflectometer electron density diagnostic for laser and pulsed power high energy density plasma experiments (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Valdivia, M. P., E-mail: mpvaldivia@pha.jhu.edu; Stutman, D. [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, Maryland 21218 (United States); Stoeckl, C.; Mileham, C.; Begishev, I. A.; Theobald, W.; Bromage, J.; Regan, S. P. [Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14623 (United States); Klein, S. R. [Center for Laser Experimental Astrophysical Research, University of Michigan, Ann Arbor, Michigan 48105 (United States); Muñoz-Cordovez, G.; Vescovi, M.; Valenzuela-Villaseca, V.; Veloso, F. [Instituto de Física, Pontificia Universidad Católica de Chile, Macul, Santiago (Chile)

    2016-11-15

    Talbot-Lau X-ray deflectometry (TXD) has been developed as an electron density diagnostic for High Energy Density (HED) plasmas. The technique can deliver x-ray refraction, attenuation, elemental composition, and scatter information from a single Moiré image. An 8 keV Talbot-Lau interferometer was deployed using laser and x-pinch backlighters. Grating survival and electron density mapping were demonstrated for 25–29 J, 8–30 ps laser pulses using copper foil targets. Moiré pattern formation and grating survival were also observed using a copper x-pinch driven at 400 kA, ∼1 kA/ns. These results demonstrate the potential of TXD as an electron density diagnostic for HED plasmas.

  15. Image analysis of plasma using Labview

    CERN Document Server

    Battur, Batchimeg

    2015-01-01

    Producing and trapping of antihydrogen strongly depends on production of positron plasmas of low temperatures. Therefore the ALPHA experiment is immensely interested in reducing the temperature of positrons that are being attained in the current experiment. In recent experiments a new way of cooling of positrons has been demonstrated - sympathetic cooling. In this method the Beryllium (in our case) ions are cooled down by a laser to very low temperature and mixed with positrons. They collide with each other, resulting in cooled positrons.

  16. Identification and Plasma Diagnostics Study of Extreme Ultraviolet Transitions in Highly Charged Yttrium

    Directory of Open Access Journals (Sweden)

    Roshani Silwal

    2017-09-01

    Full Text Available Extreme ultraviolet spectra of the L-shell ions of highly charged yttrium (Y 26 + –Y 36 + were observed in the electron beam ion trap of the National Institute of Standards and Technology using a flat-field grazing-incidence spectrometer in the wavelength range of 4 nm-20 nm. The electron beam energy was systematically varied from 2.3 keV–6.0 keV to selectively produce different ionization stages. Fifty-nine spectral lines corresponding to Δ n = 0 transitions within the n = 2 and n = 3 shells have been identified using detailed collisional-radiative (CR modeling of the non-Maxwellian plasma. The uncertainties of the wavelength determinations ranged between 0.0004 nm and 0.0020 nm. Li-like resonance lines, 2s– 2 p 1 / 2 and 2s–2 p 3 / 2 , and the Na-like D lines, 3s– 3 p 1 / 2 and 3s– 3 p 3 / 2 , have been measured and compared with previous measurements and calculations. Forbidden magnetic dipole (M1 transitions were identified and analyzed for their potential applicability in plasma diagnostics using large-scale CR calculations including approximately 1.5 million transitions. Several line ratios were found to show strong dependence on electron density and, hence, may be implemented in the diagnostics of hot plasmas, in particular in fusion devices.

  17. Pott's Spine: Diagnostic Imaging Modalities and Technology Advancements

    Science.gov (United States)

    Ansari, Sajid; Amanullah, Md. Farid; Ahmad, Kaleem; Rauniyar, Raj Kumar

    2013-01-01

    Spinal tuberculosis (TB) or Pott's spine is the commonest extrapulmonary manifestation of TB. It spreads through hematogenous route. Clinically, it presents with constitutional symptoms, back pain, tenderness, paraplegia or paraparesis, and kyphotic or scoliotic deformities. Pott's spine accounts for 2% of all cases of TB, 15% of extrapulmonary, and 50% of skeletal TB. The paradiscal, central, anterior subligamentous, and neural arch are the common vertebral lesions. Thoracic vertebrae are commonly affected followed by lumbar and cervical vertebrae. Plain radiographs are usually the initial investigation in spinal TB. For a radiolucent lesion to be apparent on a plain radiograph there should be 30% of bone mineral loss. Computed tomographic scanning provides much better bony detail of irregular lytic lesions, sclerosis, disc collapse, and disruption of bone circumference than plain radiograph. Magnetic resonance imaging (MRI) is the best diagnostic modality for Pott's spine and is more sensitive than other modalities. MRI frequently demonstrates disc collapse/destruction, cold abscess, vertebral wedging/collapse, marrow edema, and spinal deformities. Ultrasound and computed tomographic guided needle aspiration or biopsy is the technique for early histopathological diagnosis. Recently, the coexistence of human immunodeficiency virus infections and TB has been increased globally. In recent years, diffusion-weighted MRI (DW-MRI) and apparent diffusion coefficient values in combination with MRI are used to some extent in the diagnosis of spinal TB. We have reviewed related literature through internet. The terms searched on Google scholar and PubMed are TB, extrapulmonary TB, skeletal TB, spinal TB, Pott's spine, Pott's paraplegia, MRI, and computed tomography (CT). PMID:24020048

  18. A high-speed two-frame, 1-2 ns gated X-ray CMOS imager used as a hohlraum diagnostic on the National Ignition Facility (invited)

    Science.gov (United States)

    Chen, Hui; Palmer, N.; Dayton, M.; Carpenter, A.; Schneider, M. B.; Bell, P. M.; Bradley, D. K.; Claus, L. D.; Fang, L.; Hilsabeck, T.; Hohenberger, M.; Jones, O. S.; Kilkenny, J. D.; Kimmel, M. W.; Robertson, G.; Rochau, G.; Sanchez, M. O.; Stahoviak, J. W.; Trotter, D. C.; Porter, J. L.

    2016-11-01

    A novel x-ray imager, which takes time-resolved gated images along a single line-of-sight, has been successfully implemented at the National Ignition Facility (NIF). This Gated Laser Entrance Hole diagnostic, G-LEH, incorporates a high-speed multi-frame CMOS x-ray imager developed by Sandia National Laboratories to upgrade the existing Static X-ray Imager diagnostic at NIF. The new diagnostic is capable of capturing two laser-entrance-hole images per shot on its 1024 × 448 pixels photo-detector array, with integration times as short as 1.6 ns per frame. Since its implementation on NIF, the G-LEH diagnostic has successfully acquired images from various experimental campaigns, providing critical new information for understanding the hohlraum performance in inertial confinement fusion (ICF) experiments, such as the size of the laser entrance hole vs. time, the growth of the laser-heated gold plasma bubble, the change in brightness of inner beam spots due to time-varying cross beam energy transfer, and plasma instability growth near the hohlraum wall.

  19. Image Analysis of Plasma Induced by Focused IR Pulsed Laser

    Directory of Open Access Journals (Sweden)

    Ahmad Hadi Ali

    2011-12-01

    Full Text Available Plasma induced by focused laser beam is very essential especially in laser material interaction. Preliminary study leading to this research has been carried out. A Q-switch Nd:YAG laser was employed as a source of energy. The laser was focused using a wide-angle camera lens. The formation of plasma at the focal region was visualized perpendicularly using a CCD video camera interfaced to an image processing system. The dynamic expansion of the laser plasma was grabbed in conjunction with a high-speed photographic system. The observation results show that the plasma was formed in an ellipsoidal shape. The lateral width and the length of the plasma were found gradually increased

  20. Mapping the different methods adopted for diagnostic imaging instruction at medical schools in Brazil.

    Science.gov (United States)

    Chojniak, Rubens; Carneiro, Dominique Piacenti; Moterani, Gustavo Simonetto Peres; Duarte, Ivone da Silva; Bitencourt, Almir Galvão Vieira; Muglia, Valdair Francisco; D'Ippolito, Giuseppe

    2017-01-01

    To map the different methods for diagnostic imaging instruction at medical schools in Brazil. In this cross-sectional study, a questionnaire was sent to each of the coordinators of 178 Brazilian medical schools. The following characteristics were assessed: teaching model; total course hours; infrastructure; numbers of students and professionals involved; themes addressed; diagnostic imaging modalities covered; and education policies related to diagnostic imaging. Of the 178 questionnaires sent, 45 (25.3%) were completed and returned. Of those 45 responses, 17 (37.8%) were from public medical schools, whereas 28 (62.2%) were from private medical schools. Among the 45 medical schools evaluated, the method of diagnostic imaging instruction was modular at 21 (46.7%), classic (independent discipline) at 13 (28.9%), hybrid (classical and modular) at 9 (20.0%), and none of the preceding at 3 (6.7%). Diagnostic imaging is part of the formal curriculum at 36 (80.0%) of the schools, an elective course at 3 (6.7%), and included within another modality at 6 (13.3%). Professors involved in diagnostic imaging teaching are radiologists at 43 (95.5%) of the institutions. The survey showed that medical courses in Brazil tend to offer diagnostic imaging instruction in courses that include other content and at different time points during the course. Radiologists are extensively involved in undergraduate medical education, regardless of the teaching methodology employed at the institution.

  1. Mapping the different methods adopted for diagnostic imaging instruction at medical schools in Brazil

    Science.gov (United States)

    Chojniak, Rubens; Carneiro, Dominique Piacenti; Moterani, Gustavo Simonetto Peres; Duarte, Ivone da Silva; Bitencourt, Almir Galvão Vieira; Muglia, Valdair Francisco; D'Ippolito, Giuseppe

    2017-01-01

    Objective To map the different methods for diagnostic imaging instruction at medical schools in Brazil. Materials and Methods In this cross-sectional study, a questionnaire was sent to each of the coordinators of 178 Brazilian medical schools. The following characteristics were assessed: teaching model; total course hours; infrastructure; numbers of students and professionals involved; themes addressed; diagnostic imaging modalities covered; and education policies related to diagnostic imaging. Results Of the 178 questionnaires sent, 45 (25.3%) were completed and returned. Of those 45 responses, 17 (37.8%) were from public medical schools, whereas 28 (62.2%) were from private medical schools. Among the 45 medical schools evaluated, the method of diagnostic imaging instruction was modular at 21 (46.7%), classic (independent discipline) at 13 (28.9%), hybrid (classical and modular) at 9 (20.0%), and none of the preceding at 3 (6.7%). Diagnostic imaging is part of the formal curriculum at 36 (80.0%) of the schools, an elective course at 3 (6.7%), and included within another modality at 6 (13.3%). Professors involved in diagnostic imaging teaching are radiologists at 43 (95.5%) of the institutions. Conclusion The survey showed that medical courses in Brazil tend to offer diagnostic imaging instruction in courses that include other content and at different time points during the course. Radiologists are extensively involved in undergraduate medical education, regardless of the teaching methodology employed at the institution. PMID:28298730

  2. Wavelet-analysis for Laser Images of Blood Plasma

    Directory of Open Access Journals (Sweden)

    ANGELSKY, A.-P.

    2011-05-01

    Full Text Available The possibilities of the local wavelet-analysis of polarization-inhomogeneous laser image of human blood plasma were considered. The set of statistics, correlation and fractal parameters of the distributions of wavelet-coefficients that are characterize different scales of the polarization maps of polycrystalline networks of amino acids of blood plasma were defined. The criteria for the differentiation of the transformation of birefringence optical-anisotropic structures of blood plasma at different scales of their geometric dimensions were determined.

  3. Testing of a pulsed He supersonic beam for plasma edge diagnostic in the TJ-IU torsatron

    Science.gov (United States)

    Tabarés, F. L.; Tafalla, D.; Herrero, V.; Tanarro, I.

    1997-02-01

    A new, compact atomic beam source based on the supersonic expansion of He has been developed for application as a plasma edge diagnostic. The beam is produced from a pulsed valve with a duration between 0.2 to 2 ms and a nominal repetition rate 10 and a divergence of ± 1° have been achieved at stagnation pressures below 2 bar. The diagnostic has been tested in ECRH plasmas on the TJ-IU torsatron, representing the first application of a supersonic beam to plasma characterization, to our knowledge. Operational conditions which minimized the total amount of He injected into the plasma were chosen. Non-perturbative injection conditions in the low density plasmas could be obtained at local He densities of ⋍ 1 × 10 11 cm -3 and a beam diameter < 1 cm. Due to the relatively low electron density of the ECRH plasmas, and to the good penetration characteristics of the supersonic He beam, the diagnostic could be used up to fairly low values of the normalized plasma minor radius, {r}/{a} (a = 12 cm) . Details of the optimization of the atomic beam diagnostics and typical results for steady state conditions in the TJ-IU plasmas are presented.

  4. Testing of a pulsed He supersonic beam for plasma edge diagnostic in the TJ-IU torsatron

    Energy Technology Data Exchange (ETDEWEB)

    Tabares, F.L. [Association EURATOM/CIEMAT, Madrid (Spain); Tafalla, D. [Association EURATOM/CIEMAT, Madrid (Spain); Herrero, V. [Instituto de Estructura de la Materia, CSIC, 28006 Madrid (Spain); Tanarro, I. [Instituto de Estructura de la Materia, CSIC, 28006 Madrid (Spain)

    1997-02-01

    A new, compact atomic beam source based on the supersonic expansion of He has been developed for application as a plasma edge diagnostic. The beam is produced from a pulsed valve with a duration between 0.2 to 2 ms and a nominal repetition rate <500 Hz. A terminal speed ratio >10 and a divergence of {+-}1 have been achieved at stagnation pressures below 2 bar. The diagnostic has been tested in ECRH plasmas on the TJ-IU torsatron, representing the first application of a supersonic beam to plasma characterization, to our knowledge. Operational conditions which minimized the total amount of He injected into the plasma were chosen. Non-perturbative injection conditions in the low density plasmas could be obtained at local He densities of {approx_equal}1 x 10{sup 11} cm{sup -3} and a beam diameter <1 cm. Due to the relatively low electron density of the ECRH plasmas, and to the good penetration characteristics of the supersonic He beam, the diagnostic could be used up to fairly low values of the normalized plasma minor radius, r/a (a=12 cm). Details of the optimization of the atomic beam diagnostics and typical results for steady state conditions in the TJ-IU plasmas are presented. (orig.).

  5. Fast imaging diagnostics on the C-2U advanced beam-driven field-reversed configuration device

    Science.gov (United States)

    Granstedt, E. M.; Petrov, P.; Knapp, K.; Cordero, M.; Patel, V.

    2016-11-01

    The C-2U device employed neutral beam injection, end-biasing, and various particle fueling techniques to sustain a Field-Reversed Configuration (FRC) plasma. As part of the diagnostic suite, two fast imaging instruments with radial and nearly axial plasma views were developed using a common camera platform. To achieve the necessary viewing geometry, imaging lenses were mounted behind re-entrant viewports attached to welded bellows. During gettering, the vacuum optics were retracted and isolated behind a gate valve permitting their removal if cleaning was necessary. The axial view incorporated a stainless-steel mirror in a protective cap assembly attached to the vacuum-side of the viewport. For each system, a custom lens-based, high-throughput optical periscope was designed to relay the plasma image about half a meter to a high-speed camera. Each instrument also contained a remote-controlled filter wheel, set between shots to isolate a particular hydrogen or impurity emission line. The design of the camera platform, imaging performance, and sample data for each view is presented.

  6. Fast imaging diagnostics on the C-2U advanced beam-driven field-reversed configuration device

    Energy Technology Data Exchange (ETDEWEB)

    Granstedt, E. M., E-mail: egranstedt@trialphaenergy.com; Petrov, P.; Knapp, K.; Cordero, M.; Patel, V. [Tri Alpha Energy, P.O. Box 7010, Rancho Santa Margarita, California 92688 (United States)

    2016-11-15

    The C-2U device employed neutral beam injection, end-biasing, and various particle fueling techniques to sustain a Field-Reversed Configuration (FRC) plasma. As part of the diagnostic suite, two fast imaging instruments with radial and nearly axial plasma views were developed using a common camera platform. To achieve the necessary viewing geometry, imaging lenses were mounted behind re-entrant viewports attached to welded bellows. During gettering, the vacuum optics were retracted and isolated behind a gate valve permitting their removal if cleaning was necessary. The axial view incorporated a stainless-steel mirror in a protective cap assembly attached to the vacuum-side of the viewport. For each system, a custom lens-based, high-throughput optical periscope was designed to relay the plasma image about half a meter to a high-speed camera. Each instrument also contained a remote-controlled filter wheel, set between shots to isolate a particular hydrogen or impurity emission line. The design of the camera platform, imaging performance, and sample data for each view is presented.

  7. Influence of excited state spatial distributions on plasma diagnostics: Atmospheric pressure laser-induced He-H2 plasma

    Science.gov (United States)

    Monfared, Shabnam K.; Hüwel, Lutz

    2012-10-01

    Atmospheric pressure plasmas in helium-hydrogen mixtures with H2 molar concentrations ranging from 0.13% to 19.7% were investigated at times from 1 to 25 μs after formation by a Q-switched Nd:YAG laser. Spatially integrated electron density values are obtained using time resolved optical emission spectroscopic techniques. Depending on mixture concentration and delay time, electron densities vary from almost 1017 cm-3 to about 1014 cm-3. Helium based results agree reasonably well with each other, as do values extracted from the Hα and Hβ emission lines. However, in particular for delays up to about 7 μs and in mixtures with less than 1% hydrogen, large discrepancies are observed between results obtained from the two species. Differences decrease with increasing hydrogen partial pressure and/or increasing delay time. In mixtures with molecular hydrogen fraction of 7% or more, all methods yield electron densities that are in good agreement. These findings seemingly contradict the well-established idea that addition of small amounts of hydrogen for diagnostic purposes does not perturb the plasma. Using Abel inversion analysis of the experimental data and a semi-empirical numerical model, we demonstrate that the major part of the detected discrepancies can be traced to differences in the spatial distributions of excited helium and hydrogen neutrals. The model yields spatially resolved emission intensities and electron density profiles that are in qualitative agreement with experiment. For the test case of a 1% H2 mixture at 5 μs delay, our model suggests that high electron temperatures cause an elevated degree of ionization and thus a reduction of excited hydrogen concentration relative to that of helium near the plasma center. As a result, spatially integrated analysis of hydrogen emission lines leads to oversampling of the plasma perimeter and thus to lower electron density values compared to those obtained from helium lines.

  8. A diagnostic system for electrical faults in a high current discharge plasma setup.

    Science.gov (United States)

    Nigam, S; Aneesh, K; Navathe, C P; Gupta, P D

    2011-02-01

    A diagnostic system to detect electrical faults inside a coaxial high current discharge device is presented here. This technique utilizes two biconical antennas picking up electromagnetic radiation from the discharge device, a voltage divider sensing input voltage, and a Rogowski coil measuring the main discharge current. A computer program then analyses frequency components in these signals and provides information as to whether the discharge event was normal or any breakdown fault occurred inside the coaxial device. The diagnostic system is developed for a 450 kV and 50 kA capillary discharge plasma setup. For the setup various possible faults are analyzed by electrical simulation, followed by experimental results. In the case of normal discharge through the capillary load the dominant frequency is ∼4 MHz. Under faulty conditions, the peak in magnitude versus frequency plot of the antenna signal changes according to the fault position which involves different paths causing variation in the equivalent circuit elements.

  9. Additive Manufacture (3D Printing) of Plasma Diagnostic Components and Assemblies for Fusion Experiments

    Science.gov (United States)

    Quinley, Morgan; Chun, Katherine; Melnik, Paul; Sieck, Paul; Smith, Trevor; Stuber, James; Woodruff, Simon; Romero-Talamas, Carlos; Rivera, William; Card, Alexander

    2016-10-01

    We are investigating the potential impact of additive manufacturing (3D printing) on the cost and complexity of plasma diagnostics. We present a survey of the current state-of-the-art in additive manufacture of metals, as well as the design of diagnostic components that have been optimized for and take advantage of these processes. Included among these is a set of retarding field analyzer probe heads that have been printed in tungsten with internal heat sinks and cooling channels. Finite element analysis of these probe heads shows the potential for a 750K reduction in peak temperature, allowing the probe to take data twice as often without melting. Results of the evaluation of these probe heads for mechanical strength and outgassing, as well as their use on Alcator C-Mod will be presented. Supported by DOE SBIR Grant DE-SC0011858.

  10. A diagnostic system for electrical faults in a high current discharge plasma setup

    Science.gov (United States)

    Nigam, S.; Aneesh, K.; Navathe, C. P.; Gupta, P. D.

    2011-02-01

    A diagnostic system to detect electrical faults inside a coaxial high current discharge device is presented here. This technique utilizes two biconical antennas picking up electromagnetic radiation from the discharge device, a voltage divider sensing input voltage, and a Rogowski coil measuring the main discharge current. A computer program then analyses frequency components in these signals and provides information as to whether the discharge event was normal or any breakdown fault occurred inside the coaxial device. The diagnostic system is developed for a 450 kV and 50 kA capillary discharge plasma setup. For the setup various possible faults are analyzed by electrical simulation, followed by experimental results. In the case of normal discharge through the capillary load the dominant frequency is ˜4 MHz. Under faulty conditions, the peak in magnitude versus frequency plot of the antenna signal changes according to the fault position which involves different paths causing variation in the equivalent circuit elements.

  11. Companion diagnostics and molecular imaging-enhanced approaches for oncology clinical trials.

    Science.gov (United States)

    Van Heertum, Ronald L; Scarimbolo, Robert; Ford, Robert; Berdougo, Eli; O'Neal, Michael

    2015-01-01

    In the era of personalized medicine, diagnostic approaches are helping pharmaceutical and biotechnology sponsors streamline the clinical trial process. Molecular assays and diagnostic imaging are routinely being used to stratify patients for treatment, monitor disease, and provide reliable early clinical phase assessments. The importance of diagnostic approaches in drug development is highlighted by the rapidly expanding global cancer diagnostics market and the emergent attention of regulatory agencies worldwide, who are beginning to offer more structured platforms and guidance for this area. In this paper, we highlight the key benefits of using companion diagnostics and diagnostic imaging with a focus on oncology clinical trials. Nuclear imaging using widely available radiopharmaceuticals in conjunction with molecular imaging of oncology targets has opened the door to more accurate disease assessment and the modernization of standard criteria for the evaluation, staging, and treatment responses of cancer patients. Furthermore, the introduction and validation of quantitative molecular imaging continues to drive and optimize the field of oncology diagnostics. Given their pivotal role in disease assessment and treatment, the validation and commercialization of diagnostic tools will continue to advance oncology clinical trials, support new oncology drugs, and promote better patient outcomes.

  12. Analysis and Interpretation of the Plasma Dynamic Response to Additional Heating Power using different Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Manini, A

    2002-07-01

    The main goal in the research of nuclear fusion, and therefore in tokamak research as well, is the development of a high power, steady-state power plant. To obtain the high power required for igniting the plasma, the size of the device must be very large. The performance of the tokamak plasma depends in particular on the plasma shape and on the internal plasma profiles. These profiles include those of the current density and the pressure, two quantities that can be modified by means of auxiliary heating methods such as Electron Cyclotron Heating (ECH). ECH is a very important tool due to its capability of injecting highly localised and intense power. Off-axis ECH and Electron Cyclotron Current Drive (ECCD) modify both current density and electron temperature profiles, leading to modification of confinement and stability properties. in particular, complete stabilisation of magnetohydrodynamic modes using ECCD is feasible. Furthermore, ECH is crucial as a mean of increasing the bootstrap current fraction through the formation of internal transport barriers, so that confinement is also improved. Finally, it is also noted that modulated ECH (MECH) is a very effective tool for perturbative energy transport experiments in many different regimes. Experiments performed in the TCV and the ASDEX Upgrade tokamaks are presented. The role of TCV is very important due to its flexibility of varying the plasma shape, its versatile high power ECH system at both the second and third electron cyclotron harmonics, and due to the numerous diagnostics installed, e.g. the two soft X-ray (SXR) diagnostics which simultaneously allow high temporal and spatial resolutions. The importance of ASDEX Upgrade is related to its large size, which makes it a reactor-relevant experimental facility, and to the Neutral Beam Injection (NBI) and ECH heating facilities, which allow a study of heat and particle transport in either mostly ion-heated or mostly electron-heated regimes. Moreover, for the

  13. Medical physics: some recollections in diagnostic X-ray imaging and therapeutic radiology.

    Science.gov (United States)

    Gray, J E; Orton, C G

    2000-12-01

    Medical physics has changed dramatically since 1895. There was a period of slow evolutionary change during the first 70 years after Roentgen's discovery of x rays. With the advent of the computer, however, both diagnostic and therapeutic radiology have undergone rapid growth and changes. Technologic advances such as computed tomography and magnetic resonance imaging in diagnostic imaging and three-dimensional treatment planning systems, stereotactic radiosurgery, and intensity modulated radiation therapy in radiation oncology have resulted in substantial changes in medical physics. These advances have improved diagnostic imaging and radiation therapy while expanding the need for better educated and experienced medical physics staff.

  14. Spectroscopic diagnostics of superthermal electrons with high-number harmonic EC radiation in tokamak reactor plasmas

    Directory of Open Access Journals (Sweden)

    Minashin P.V.

    2015-01-01

    Full Text Available A method of spectroscopic diagnostics of the average perpendicular-to-magnetic-field momentum of the superthermal component of the electron velocity distribution (EVD, based on the high-number-harmonic electron cyclotron (EC radiation, is suggested for nuclear fusion-reactor plasmas under condition of a strong auxiliary heating (e.g. in tokamak DEMO, a next step after tokamak ITER. The method is based on solving an inverse problem for reconstruction of the EVD in parallel and perpendicular-to-magnetic-field components of electron momentum at high and moderate energies responsible for the emission of the high-number-harmonic EC radiation.

  15. Cell-free DNA promoter hypermethylation in plasma as a diagnostic marker for pancreatic adenocarcinoma

    DEFF Research Database (Denmark)

    Henriksen, Stine Dam; Madsen, Poul Henning; Larsen, Anders Christian;

    2016-01-01

    analysis using backward stepwise elimination. RESULTS: Patients with pancreatic adenocarcinoma (n = 95), chronic pancreatitis (n = 97) and acute pancreatitis (n = 59) and patients screened, but negative for pancreatic adenocarcinoma (n = 27), were included. The difference in mean number of methylated genes...... with chronic/acute pancreatitis were included as additional benign control groups. Based on an optimized accelerated bisulfite treatment protocol, methylation-specific PCR of a 28 gene panel was performed on plasma samples. A diagnostic prediction model was developed by multivariable logistic regression...

  16. Investigation of relativistic laser-plasmas using nuclear diagnostics; Untersuchung relativistischer Laserplasmen mittels nukleardiagnostischer Verfahren

    Energy Technology Data Exchange (ETDEWEB)

    Guenther, Marc M.

    2011-01-19

    The present work explores with the development of a novel nuclear diagnostic method for the investigation of the electron dynamics in relativistic laser-plasma interactions. An additional aim of this work was the determination of the real laser peak intensity via the interaction of an intense laser short-pulse with a solid target. The nuclear diagnostics is based on a photo-neutron disintegration nuclear activation method. The main constituent of the nuclear diagnostic are novel pseudoalloic activation targets as a kind of calorimeter to measure the high-energy bremsstrahlung produced by relativistic electrons. The targets are composed of several stable isotopes with different ({gamma},xn)-reaction thresholds. The activated nuclides were identified via the characteristic gamma-ray decay spectrum by using high-resolution gamma spectroscopy after the laser irradiation. Via the gamma spectroscopy the ({gamma},xn)-reaction yields were determined. The high-energy bremsstrahlung spectrum has been deconvolved using a novel analysis method based on a modified Penfold-Leiss method. This facilitates the reconstruction of the spectrum of bremsstrahlung photons without any anticipated fit procedures. Furthermore, the characterization of the corresponding bremsstrahlung electrons in the interaction zone is accessible immediately. The consolidated findings about the properties of the relativistic electrons were used to determine the real peak intensity at the laser-plasma interaction zone. In the context of this work, experiments were performed at three different laser facilities. First Experiments were carried out at the 100 TW laser facility at Laboratoire pour l'Utilisation des Lasers Intense (LULI) in France and supplementary at the Vulcan laser facility at Rutherford Appleton Laboratory (RAL) in United Kingdom. The main part of the activation experiments were performed at the PHELIX laser facility (Petawatt High Energy Laser for heavy Ion EXperiments) at GSI

  17. Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa.

    Science.gov (United States)

    Näsström, Elin; Parry, Christopher M; Vu Thieu, Nga Tran; Maude, Rapeephan R; de Jong, Hanna K; Fukushima, Masako; Rzhepishevska, Olena; Marks, Florian; Panzner, Ursula; Im, Justin; Jeon, Hyonjin; Park, Seeun; Chaudhury, Zabeen; Ghose, Aniruddha; Samad, Rasheda; Van, Tan Trinh; Johansson, Anders; Dondorp, Arjen M; Thwaites, Guy E; Faiz, Abul; Antti, Henrik; Baker, Stephen

    2017-05-09

    Salmonella Typhi is the causative agent of typhoid. Typhoid is diagnosed by blood culture, a method that lacks sensitivity, portability and speed. We have previously shown that specific metabolomic profiles can be detected in the blood of typhoid patients from Nepal (Näsström et al., 2014). Here, we performed mass spectrometry on plasma from Bangladeshi and Senegalese patients with culture confirmed typhoid fever, clinically suspected typhoid, and other febrile diseases including malaria. After applying supervised pattern recognition modelling, we could significantly distinguish metabolite profiles in plasma from the culture confirmed typhoid patients. After comparing the direction of change and degree of multivariate significance, we identified 24 metabolites that were consistently up- or down regulated in a further Bangladeshi/Senegalese validation cohort, and the Nepali cohort from our previous work. We have identified and validated a metabolite panel that can distinguish typhoid from other febrile diseases, providing a new approach for typhoid diagnostics.

  18. Ion Source for Neutral beam injection meant for plasma and magnetic field diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Vainionpaa, Jaakko Hannes; Leung, Ka Ngo; Gough, Richard A.; Kwan, Joe W.; Levinton, Fred

    2007-06-01

    At the Lawrence Berkeley National Laboratory (LBNL) a diagnostic neutral beam injection system for measuring plasma parameters, flow velocity, and local magnetic field is being developed. The systems is designed to have a 90 % proton fraction and small divergence with beam current at 5-6 A and a pulse length of {approx}1 s occurring once every 1-2 min. The ion source needs to generate uniform plasma over a large (8 cm x 5 cm) extraction area. For this application, we have compared RF driven multicusp ion sources operating with either an external or an internal antenna in similar ion source geometry. The ion beam will be made of an array of six sheet-shaped beamlets. The design is optimized using computer simulation programs.

  19. Analysis and Interpretation of the Plasma Dynamic Response to Additional Heating Power using different Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Manini, A

    2002-07-01

    The main goal in the research of nuclear fusion, and therefore in tokamak research as well, is the development of a high power, steady-state power plant. To obtain the high power required for igniting the plasma, the size of the device must be very large. The performance of the tokamak plasma depends in particular on the plasma shape and on the internal plasma profiles. These profiles include those of the current density and the pressure, two quantities that can be modified by means of auxiliary heating methods such as Electron Cyclotron Heating (ECH). ECH is a very important tool due to its capability of injecting highly localised and intense power. Off-axis ECH and Electron Cyclotron Current Drive (ECCD) modify both current density and electron temperature profiles, leading to modification of confinement and stability properties. in particular, complete stabilisation of magnetohydrodynamic modes using ECCD is feasible. Furthermore, ECH is crucial as a mean of increasing the bootstrap current fraction through the formation of internal transport barriers, so that confinement is also improved. Finally, it is also noted that modulated ECH (MECH) is a very effective tool for perturbative energy transport experiments in many different regimes. Experiments performed in the TCV and the ASDEX Upgrade tokamaks are presented. The role of TCV is very important due to its flexibility of varying the plasma shape, its versatile high power ECH system at both the second and third electron cyclotron harmonics, and due to the numerous diagnostics installed, e.g. the two soft X-ray (SXR) diagnostics which simultaneously allow high temporal and spatial resolutions. The importance of ASDEX Upgrade is related to its large size, which makes it a reactor-relevant experimental facility, and to the Neutral Beam Injection (NBI) and ECH heating facilities, which allow a study of heat and particle transport in either mostly ion-heated or mostly electron-heated regimes. Moreover, for the

  20. Diagnostic Imaging in the Medical Support of the Future Missions to the Moon

    Science.gov (United States)

    Sargsyan, Ashot E.; Jones, Jeffrey A.; Hamilton, Douglas R.; Dulchavsky, Scott A.; Duncan, J. Michael

    2007-01-01

    This viewgraph presentation is a course that reviews the diagnostic imaging techniques available for medical support on the future moon missions. The educational objectives of the course are to: 1) Update the audience on the curreultrasound imaging in space flight; 2) Discuss the unique aspects of conducting ultrasound imaging on ISS, interplanetary transit, ultrasound imaging on ISS, interplanetary transit, and lunar surface operations; and 3) Review preliminary data obtained in simulations of medical imaging in lunar surface operations.

  1. LIF-imaging and gas-phase diagnostics of laser desorbed MALDI-matrix plumes

    Energy Technology Data Exchange (ETDEWEB)

    Puretzky, A.A.; Geohegan, D.B. [Oak Ridge National Lab., TN (United States). Solid State Div.

    1997-07-01

    The first gated LIF-imaging and absorption spectroscopy has been performed on laser desorbed plumes from organic crystals which are commonly used as MALDI (Matrix Assisted Laser Desorption Ionization) matrices. These plasma diagnostic techniques, including ion probe measurements were employed to investigate the desorbed products, densities, fractional ionization, and velocity distributions of the plume of ejecta which is typically employed as the main desorption product in the mass spectrometry analysis of large biomolecules. Ultraviolet pulsed 193-nm and 248-nm irradiation of 3-hydroxypicolinic acid (3-HPA) crystals were studied to understand the effect of very different gas-phase absorption cross sections measured here for this material. In both cases, LIF imaging revealed two plume components: a fast (maximum {approximately} 0.1 cm/{micro}s) low-intensity component which appear to be 3-HPA fragments, and a slower component of 3-HPA expanding at 0.05 cm/{micro}s. In the case of ArF-laser irradiation, optical absorption spectroscopy indicated a breaking of the intramolecular hydrogen bond in the gas-phase matrix material.

  2. Optimization of diagnostic imaging use in patients with acute abdominal pain (OPTIMA: Design and rationale

    Directory of Open Access Journals (Sweden)

    Bossuyt Patrick MM

    2007-08-01

    Full Text Available Abstract Background The acute abdomen is a frequent entity at the Emergency Department (ED, which usually needs rapid and accurate diagnostic work-up. Diagnostic work-up with imaging can consist of plain X-ray, ultrasonography (US, computed tomography (CT and even diagnostic laparoscopy. However, no evidence-based guidelines exist in current literature. The actual diagnostic work-up of a patient with acute abdominal pain presenting to the ED varies greatly between hospitals and physicians. The OPTIMA study was designed to provide the evidence base for constructing an optimal diagnostic imaging guideline for patients with acute abdominal pain at the ED. Methods/design Thousand consecutive patients with abdominal pain > 2 hours and Discussion This study aims to provide the evidence base for the development of a diagnostic algorithm that can act as a guideline for ED physicians to evaluate patients with acute abdominal pain.

  3. Drifting plasma collection by a positive biased tether wire in LEO-like plasma conditions: current measurement and plasma diagnostic

    OpenAIRE

    Siguier, Jean-Michel; Sarrailh, Pierre; Roussel, Jean-François; Inguimbert, Virgine; Murat, Gaël; Sanmartín Losada, Juan Ramón

    2013-01-01

    BETs is a three-year project financed by the Space Program of the European Commission, aimed at developing an efficient deorbit system that could be carried on board any future satellite launched into Low Earth Orbit (LEO). The operational system involves a conductive tape-tether left bare to establish anodic contact with the ambient plasma as a giant Langmuir probe. As a part of this project, we are carrying out both numerical and experimental approaches to estimate the collected current by ...

  4. Diagnostic Imaging Integrated Network: A Teleradiology Pilot in Public Hospitals in Uruguay.

    Science.gov (United States)

    Acosta, Lilian; Ruibal Faral, Karime

    2015-01-01

    A network of health care centers allows radiologists to share diagnostic images in different areas of Uruguay. This solution is based on an informatics multicenter application for center management, enabling the creation, storage and distribution of images and reports from different imaging modalities according to outsourcing agreements. The solution improves health care territorial equity and reduces asymmetry in resources distribution.

  5. Kinetic and Diagnostic Studies of Molecular Plasmas Using Laser Absorption Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Welzel, S [INP-Greifswald, 17489 Greifswald, Felix-Hausdorff-Str. 2 (Germany); Rousseau, A [Laboratoire de Physique et Technologie des Plasmas, Ecole Polytechnique, CNRS, 91128 Palaiseau (France); Davies, P B [Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW (United Kingdom); Roepcke, J [INP-Greifswald, 17489 Greifswald, Felix-Hausdorff-Str. 2 (Germany)

    2007-10-15

    Within the last decade mid infrared absorption spectroscopy between 3 and 20 {mu}m, known as Infrared Laser Absorption Spectroscopy (IRLAS) and based on tuneable semiconductor lasers, namely lead salt diode lasers, often called tuneable diode lasers (TDL), and quantum cascade lasers (QCL) has progressed considerably as a powerful diagnostic technique for in situ studies of the fundamental physics and chemistry of molecular plasmas. The increasing interest in processing plasmas containing hydrocarbons, fluorocarbons, organo-silicon and boron compounds has lead to further applications of IRLAS because most of these compounds and their decomposition products are infrared active. IRLAS provides a means of determining the absolute concentrations of the ground states of stable and transient molecular species, which is of particular importance for the investigation of reaction kinetics. Information about gas temperature and population densities can also be derived from IRLAS measurements. A variety of free radicals and molecular ions have been detected, especially using TDLs. Since plasmas with molecular feed gases are used in many applications such as thin film deposition, semiconductor processing, surface activation and cleaning, and materials and waste treatment, this has stimulated the adaptation of infrared spectroscopic techniques to industrial requirements. The recent development of QCLs offers an attractive new option for the monitoring and control of industrial plasma processes as well as for highly time-resolved studies on the kinetics of plasma processes. The aim of the present article is threefold: (i) to review recent achievements in our understanding of molecular phenomena in plasmas (ii) to report on selected studies of the spectroscopic properties and kinetic behaviour of radicals, and (iii) to describe the current status of advanced instrumentation for TDLAS in the mid infrared.

  6. Plasma-water systems studied with optical diagnostics including sum-frequency generation spectroscopy

    Science.gov (United States)

    Ito, Tsuyohito

    2016-09-01

    Recently, various applications of plasma-water systems have been reported, such as materials synthesis, agricultural applications, and medical treatments. As one of basic studies of such systems, we are investigating water surface structure influenced by a plasma via vibrational sum-frequency generation spectroscopy. Vibrational sum-frequency generation spectroscopy is known to be an interfacially active diagnostic technique, as such process occurs in noncentrosymmetric medium. Visible and wavenumber-tunable infrared beams are simultaneously irradiated to the interface. The interfacial water has ice-like ( 3200 cm-1), liquid-like ( 3400 cm-1), and free OH (3700 cm-1) structures (assignment of the ice-like structure still remains contentious), and the intensity of the signal becomes stronger when the tunable infrared beam resonates with a vibration of the structures. The results indicate that with generating air dielectric barrier discharges for supplying reactive species to the water surface, all investigated signals originating from the above-mentioned three structures decrease. Furthermore, the signal strengths are recovered after terminating the plasma generation. We currently believe that the surface density of the reactive species should be high when they are found at the water surface. Details on the experimental results of the sum-frequency generation spectroscopy, as well as other spectroscopic results of plasma-water systems, will be presented at the conference.

  7. Development of the so-called third stage laser Thomson scattering diagnostics of plasmas

    Science.gov (United States)

    Muraoka, Katsunori; Yamagata, Yukihiko; Hisano, Taishi; Uchino, Kiichirou; Miyazaki, Koichi

    2003-10-01

    In the recent review article,^1) we indicated that the incoherent laser Thomson scattering (LTS) diagnostics of plasmas for measurements of electron densities and temperatures (or more generally EEDFs) be classified as having evolved from the first stage where a whole Thomson spectrum be obtained during a single laser pulse from plasmas having electron density of above 10^18 m-3, through the second stage where data accumulation be prerequisite for ne below 10^18 m-3, and to the third stage where a strong suppression of stray light in addition to the data accumulation be necessary to measure at an extremely small size of less than 100 μm near to material surfaces. The third stage LTS was first demonstrated for a PDP (plasma display panel)-like discharge three years ago employing a triple grating polychromator. In order to further expand its applicable ranges, we are pursuing a more general approach by taking into account such factors as laser divergence, stray light suppression and other aspects. The present status is presented. 1) K. Muraoka, K. Uchino, Y. Yamagata, Y. Noguchi, M. Mansour, P. Suanpoot, S. Narishige, and M. Noguchi, Plasma Sources Sci. Technol. 11 (2002) A143.

  8. Multiple myeloma: 18F-FDG-PET/CT and diagnostic imaging.

    Science.gov (United States)

    Mihailovic, Jasna; Goldsmith, Stanley J

    2015-01-01

    Multiple myeloma (MM) is a relatively rare hematologic disorder characterized by proliferation of plasma cells, primarily involving the bone marrow. Extramedullary involvement also occurs with poor prognosis. Asymptomatic plasma cell disorders, monoclonal gammopathy of uncertain significance, and smoldering MM, which do not require therapy, should be distinguished from symptomatic MM, which requires treatment. MM may present with CRAB, elevated Calcium levels, Renal insufficiency, Anemia, and Bone lesions (including lytic lesions and osteopenia), as well as elevated levels of serum M protein or urine M protein or both. Nonsecretory myeloma in which serum and urine M proteins are absent occurs rarely, accounting for 1%-5% of patients with myeloma, but low levels of abnormal immunoglobulins are often present. Staging of patients with MM is done according to the Durie and Salmon criteria based on laboratory testing (determination of hemoglobin, serum calcium, and serum and urine M proteins) and conventional radiography. A variety of diagnostic imaging procedures have been employed to assess the extent of disease in MM and to evaluate the response to treatment as well as provide surveillance for the detection of recurrent disease. These include whole-body x-ray, which despite its limitations is regularly used to detect lytic bone lesions; CT radiography; MRI; and a variety of radionuclide imaging procedures, with (18)F-FDG-PET/CT emerging as the radionuclide procedure of choice. Recently, the Durie-Salmon criteria have been upgrade to the Durie-Salmon PLUS system, which includes (18)F-FDG-PET/CT and MRI of the spine and pelvis.

  9. X-ray imaging and imaging spectroscopy of fusion plasmas and light-source experiments with spherical optics and pixel array detectors

    Science.gov (United States)

    Hill, K. W.; Bitter, M.; Delgado-Aparicio, L.; Pablant, N. A.; Beiersdorfer, P.; Sanchez del Rio, M.; Zhang, L.

    2012-10-01

    High resolution (λ/Δλ ~10,000) 1D imaging x-ray spectroscopy using a spherically bent crystal and a 2D hybrid pixelarray detector (PAD) is used world wide for Doppler measurements of ion-temperature (Ti) and plasma flow-velocityprofiles in magnetic confinement fusion (MCF) plasmas. Meter sized plasmas are diagnosed with cm spatial resolution and 10 ms time resolution. This concept can also be used as a diagnostic of small sources, such as inertial confinement fusion (ICF) plasmas and targets on x-ray light source beam lines, with spatial resolution of microns. A new concept of using matched pairs of spherically bent crystals for monochromatic stigmatic 2D x-ray imaging of mm sized sources offers the possibility of spatial resolution of microns and large solid angle, relative to that achieved with pinhole imaging. Other potential applications of the 2D imaging schemes include x-ray lithography and x-ray microscopy for biological and materials science research. Measurements from MFE plasmas, as well as laboratory experiments and ray tracing computations validating the 1D imaging spectroscopy and 2D x-ray imaging techniques will be presented.

  10. X-ray optical diagnostic of laser produced plasmas for nuclear fusion and X-ray lasers

    Energy Technology Data Exchange (ETDEWEB)

    Butzbach, R.

    2001-07-01

    In the present work, the conception, design and appliance of toroidally bent crystals for the X-ray optical diagnostics of laser produced plasmas is discussed. The first part of this work deals with the development, design and characterization of an X-Ray microscope for the observation of Rayleigh-Taylor instabilities, which act against the confinement and ignition of the fuel in the inertial confinement fusion process. The aim of the second part of the present work was the diagnostic of the lasing medium for amplified spontaneous emission close to the water window. For this purpose, an one-dimensionally (1-D) imaging X-ray spectrometer based on toroidally bent quartz crystals was developed for the observation of the Ni-like 4f-3d transition of Yb, Hf, Ta, and W ions, which should be related to the amplified 4d-4p emission, since the 4f niveau is very close to the 4d niveau. Thus, the 4f-3d transition can serve as an indicator for the population of the 4d niveau. (orig.)

  11. Diagnostic systems for the nuclear fusion and plasma research in the PF-24 plasma focus laboratory at the IFJ PAN

    Directory of Open Access Journals (Sweden)

    Marciniak Łukasz

    2016-12-01

    Full Text Available This paper presents a set of diagnostics dedicated to PF-24 - new medium size - plasma focus (PF device built and operated at the Institute of Nuclear Physics Polish Academy of Sciences (IFJ PAN. The PF-24 can operate at energy level up to 93 kJ and charging voltage up to 40 kV. Each condenser is connected with a specially designed spark gap with a very small jitter, which ensures a high effi ciency and a low current rise time. The working parameters of PF-24 generator make it a suitable tool for testing new detection systems to be used in fusion research. Four types of such detection systems are presented in this article: three diagnostic systems used to measure electric quantities (Rogowski coil, magnetic probe, capacitance probe, neutron counter based on beryllium activation, fast neutron pinhole camera based on small-area BCF-12 plastic scintillation detectors and high-speed four-frame soft X-ray camera with microchannel plate.

  12. Diagnostic value of lymph node metastasis by diffusion-weighted magnetic resonance imaging in cervical cancer

    Directory of Open Access Journals (Sweden)

    Xiang-Qin He

    2016-01-01

    Conclusion: The ADC values in CC tissues with LN metastasis were significantly lower than those without LN metastasis, suggesting that DWI appears to improve diagnostic performance and can be a useful adjunct imaging for identifying LN metastasis in CC patients.

  13. Rational use of diagnostic imaging in paediatrics. The report of a World Health Organization study group

    Energy Technology Data Exchange (ETDEWEB)

    Merten, D.F.; Palmer, P.E.S.; Sweet, E.M.; Fendel, H.; Faure, C.; Fujioka, M.

    1989-05-01

    The purpose of WHO Technical Report 757 is to provide guidance to physicians who must decide what imaging techniques are best suited to specific clinical problems in paediatric practice, and to those who perform these various diagnostic procedures.

  14. Millimeter-wave imaging of magnetic fusion plasmas: technology innovations advancing physics understanding

    Science.gov (United States)

    Wang, Y.; Tobias, B.; Chang, Y.-T.; Yu, J.-H.; Li, M.; Hu, F.; Chen, M.; Mamidanna, M.; Phan, T.; Pham, A.-V.; Gu, J.; Liu, X.; Zhu, Y.; Domier, C. W.; Shi, L.; Valeo, E.; Kramer, G. J.; Kuwahara, D.; Nagayama, Y.; Mase, A.; Luhmann, N. C., Jr.

    2017-07-01

    Electron cyclotron emission (ECE) imaging is a passive radiometric technique that measures electron temperature fluctuations; and microwave imaging reflectometry (MIR) is an active radar imaging technique that measures electron density fluctuations. Microwave imaging diagnostic instruments employing these techniques have made important contributions to fusion science and have been adopted at major fusion facilities worldwide including DIII-D, EAST, ASDEX Upgrade, HL-2A, KSTAR, LHD, and J-TEXT. In this paper, we describe the development status of three major technological advancements: custom mm-wave integrated circuits (ICs), digital beamforming (DBF), and synthetic diagnostic modeling (SDM). These have the potential to greatly advance microwave fusion plasma imaging, enabling compact and low-noise transceiver systems with real-time, fast tracking ability to address critical fusion physics issues, including ELM suppression and disruptions in the ITER baseline scenario, naturally ELM-free states such as QH-mode, and energetic particle confinement (i.e. Alfvén eigenmode stability) in high-performance regimes that include steady-state and advanced tokamak scenarios. Furthermore, these systems are fully compatible with today’s most challenging non-inductive heating and current drive systems and capable of operating in harsh environments, making them the ideal approach for diagnosing long-pulse and steady-state tokamaks.

  15. Plasma magnetic field diagnostic using two-photon Doppler-free LIF

    Science.gov (United States)

    Yoon, Young Dae; Bellan, Paul

    2015-11-01

    A detailed description of a new plasma B field diagnostic using Doppler-free two-photon laser-induced fluorescence is presented. The diagnostic is based on a method previously developed in the context of rubidium vapor experiments. Two counter-propagating 393nm diode laser beams are directed into an argon plasma to excite Ar-II ions from 3s2 3p4 4 s4P1 / 2 ⟶ 3s2 3p4 4 p4S3 / 2 ⟶ 3s2 3p4 4 d4P3 / 2 . These levels involve two similar (392.86 and 393.25nm) transition wavelengths, so the two counter-propagating beams effectively cancel out the Doppler effect. The excited ions then decay to the 3s2 3p4 4 p4P1 / 2 level, emitting a 324.98nm line which is to be detected by a photomultiplier tube. The Zeeman splitting -- normally unobservable because of the large Doppler broadening -- of the resultant fluorescence is then to be analyzed, yielding the magnetic field of the particular location. This method is expected to provide a 3-D localized, non-perturbing measurement of magnetic fields. An experimental implementation is currently in progress.

  16. Fourier transform infrared phase-modulated ellipsometry for in situ diagnostics of plasma-surface interactions

    Energy Technology Data Exchange (ETDEWEB)

    Shirafuji, T [International Innovation Center, Kyoto University, Sakyo-ku, Kyoto 606-8501 (Japan); Motomura, H [Department of Electronics, Kyoto University, Nishikyo-ku, Katsura 615-8510 (Japan); Tachibana, K [Department of Electronics, Kyoto University, Nishikyo-ku, Katsura 615-8510 (Japan)

    2004-03-21

    Applicability of Fourier transform infrared (FTIR) spectroscopy to an in situ diagnostics tool of plasma-surface interactions is described. After a brief review of conventional reflection absorption spectroscopy (RAS) and phase-modulated RAS (PMRAS), our FTIR phase-modulated spectroscopic ellipsometry (PMSE) is described in detail. The FTIR PMSE is constructed by insertion of a grid polarizer as an analyser in front of an infrared detector in addition to the conventional set-up of PMRAS. This simple change brings about a higher sensitivity than that of conventional PMRAS, which enables us to detect chemical species generated on (or removed from) the top surface layer during plasma processing. This feature is demonstrated by the fact that our FTIR PMSE can be applied to surface diagnostics during reactive ion etching processes such as for Si, SiO{sub 2}/Si, SiO{sub 2}/Si{sub 3}N{sub 4}, SiO{sub 2}/photo-resist and low-dielectric-constant films. (topical review)

  17. Evaluation of agreement in diagnostic imaging trials: a review of the quality of published data

    OpenAIRE

    ZHANG-YIN, Jules Tyaniu

    2015-01-01

    Background: The relevance of imaging procedures may notably vary according to clinical setting which calls for valid evaluation methods applicable to diverse clinical settings. The problem of reproducibility of the results concerns also the diagnostic imaging studies. Key issues center on substitution potential for novel radiopharmaceuticals, or easier to use medical devices vs. reference diagnostic tools. A clearly defined step wise methodology is required to plan the study and adequate stat...

  18. Cost Analysis on Imaging Diagnostic Techniques in Cerebral and Abdominal Neonatal Pathology

    OpenAIRE

    BOTAR-JID, CAROLINA; Sorin M. DUDEA; Cristiana A. CIORTEA; Sorana D. BOLBOACĂ; Anca CIUREA

    2009-01-01

    Background: Improvement of health care quality and cost control are the main aims of the health care reform in Romania. Objective: The aims of the research are to analyse the trend of costs for imaging techniques used as diagnostic tools for cerebral and abdominal neonatal pathology and to study the relationship between cost and diagnostic benefits. Design: This is a retrospective observational study design without a control group, conducted in the Radio-Imaging Department, Cluj District Univ...

  19. Image-matching as a medical diagnostic support tool (DST) for brain diseases in children.

    Science.gov (United States)

    Huang, H K; Nielsen, J F; Nelson, Marvin D; Liu, Lifeng

    2005-01-01

    Imaging-matching is an important research area in imaging informatics. We have developed and evaluated a novel diagnostic support tool (DST) based on medical image matching using MR brain images. The approach consists of two steps, database generation and image matching. The database contains pre-diagnosed MR brain images. As the images are added to the database, they are registered to the 3D Talairach coordinate system. In addition, regions of interests (ROI) are generated, and image-processing techniques are used to extract relevant image parameters related to the brain and diseases from the ROIs and from the entire MR image. The second step is to retrieve relevant information from the database by performing image matching. In this step, the physician first submits a query image. The DST computes the similarity between the query image and each of the images in the database, and then presents the most similar images to the user. Since the database contains pre-diagnosed images, the retrieved cases tend to contain relevant diagnostic information. To evaluate the usefulness of the DST in a clinical setting, pediatric brain diseases were used. The database contains 2500 pediatric patients between ages 0 and 18 with brain Magnetic Resonance (MR) images of known brain lesions. A testbed was established at the Children's Hospital Los Angeles (CHLA) for acquiring MR images from the PACS server of patients with known lesions. These images were matched against those in the DST pediatric brain MR database. An expert pediatric neuroradiologist evaluated the matched results. We found that in most cases, the image-matching method was able to quickly retrieve images with relevant diagnostic content. The evaluation method and results are given.

  20. Combined complementary plasma diagnostics to characterize a 2f plasma with additional DC current with conditioning effects at the chamber wall

    Science.gov (United States)

    Klick, Michael; Rothe, Ralf; Baek, Kye Hyun; Lee, Eunwoo

    2016-09-01

    Multiple frequencies and DC current used in a low-pressure plasma rf discharge result in an increased complexity. This needs plasma diagnostics applied, in particular in a plasma process chamber. That is done under manufacturing conditions which restrict the applicable plasma diagnostics to non-invasive methods with small footprint. So plasma chamber parameters, optical emission spectroscopy (OES), and self-excited electron spectroscopy (SEERS) are used to characterize the plasma and to understand chamber wall conditioning effects in an Ar plasma. The parameters are classified according to their origin--the region they are representative for. The center ion density is estimated from the DC current and compared to the SEERS electron density reflecting the electron density close to that at the chamber wall. The conditioning effects are caused by Si sputtering at a Si wafer changing the chamber wall state only when the chamber is clean, subsequent plasmas in the same chamber are not affected in that way. Through the combination of the complementary methods it can be shown that the chamber wall condition finally changes the radial plasma density distribution. Also the heating of electrons in the sheath is shown to be influenced by conditioning effects.

  1. Diagnostic Imaging of the Lower Respiratory Tract in Neonatal Foals: Radiography and Computed Tomography.

    Science.gov (United States)

    Lascola, Kara M; Joslyn, Stephen

    2015-12-01

    Diagnostic imaging plays an essential role in the diagnosis and monitoring of lower respiratory disease in neonatal foals. Radiography is most widely available to equine practitioners and is the primary modality that has been used for the characterization of respiratory disease in foals. Computed tomography imaging, although still limited in availability to the general practitioner, offers advantages over radiography and has been used diagnostically in neonatal foals with respiratory disease. Recognition of appropriate imaging protocols and patient-associated artifacts is critical for accurate image interpretation regardless of the modality used. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Assessing Leg length Discrepancy Using a Biplane Low Dose Imaging System. A Comparative Diagnostic Study

    DEFF Research Database (Denmark)

    Jensen, Janni; Mussmann, Bo Redder; Torfing, Trine

    study was to evaluate the diagnostic accuracy of leg length (LL) measurements performed on low dose pre-view images acquired using a new bi-planar imaging system. The administered radiation dose from the pre-view image is approximately 20,17μGycm2 vs. 2670μGycm2 when acquiring the diagnostic image......Purpose. The etiology of leg length discrepancy (LLD) is multiple and children with LLD often undergo repetitive radiographic assessment and monitoring, stressing the need for a reliable measuring tool whilst administering as little radiation to the child as possible. The aim of this retrospective...

  3. Measurement and simulation of ICRF wave intensity with a recalibrated phase contrast imaging diagnostic on Alcator C-Mod

    Energy Technology Data Exchange (ETDEWEB)

    Tsujii, N., E-mail: tsujii@k.u-tokyo.ac.jp [The University of Tokyo, Kashiwa (Japan); Porkolab, M.; Bonoli, P. T.; Edlund, E. M.; Ennever, P. C.; Lin, Y.; Wright, J. C.; Wukitch, S. J. [MIT Plasma Science and Fusion Center, Cambridge, Massachusetts (United States); Jaeger, E. F. [XCEL Engineering, Oak Ridge, Tennessee (United States); Green, D. L. [Oak Ridge National Laboratory, Oak Ridge, Tennessee (United States); Harvey, R. W. [CompX, Del Mar, California (United States)

    2015-12-10

    Waves in the ion cyclotron range of frequencies (ICRF) are one of the major tools to heat fusion plasmas. Full-wave simulations are essential to predict the wave propagation and absorption quantitatively, and it is important that these codes be validated against actual experimental measurements. In this work, the absolute intensity of the ICRF waves previously measured with a phase contrast imaging diagnostic was recalibrated and compared once more with full-wave predictions. In the earlier work, significant discrepancies were found between the measured and the simulated mode converted wave intensity [N. Tsujii et al., Phys. Plasmas 19, 082508]. With the new calibration of the detector array, the measured mode converted wave intensity is now in much better agreement with the full-wave predictions. The agreement is especially good for comparisons performed close to the antenna.

  4. Methodology for design of adaptive interfaces for diagnostic workstations with integrated images and reports

    Science.gov (United States)

    Harreld, Michael R.; Valentino, Daniel J.; Liu, Brent J.; El-Saden, Suzie; Duckwiler, Gary R.

    1998-06-01

    Diagnostic workstations have generally lacked acceptance due to awkward interfaces, poor usability and lack of clinical data integration. We developed a new methodology for the design and implementation of diagnostic workstations and applied the methodology in diagnostic neuroradiology. The methodology facilitated the objective design and evaluation of optimal diagnostic features, including the integration of images and reports, and the implementation of intelligent and adaptive graphical user interfaces. As a test of this new methodology, we developed and evaluated a neuroradiological diagnostic workstation. The general goals of diagnostic neuroradiologists were modeled and directly used in the design of the UCLA Digital ViewBox, an object-oriented toolkit for medical imaging workstations. For case-specific goals, an object-oriented protocol toolkit was developed for rapid development and integration of new protocols, modes, and tools. Each protocol defines a way to arrange and process data in order to accomplish diagnostic goals that are specific to anatomy (e.g., a spine protocol), or to a suspected pathology (e.g., a tumor protocol). Each protocol was divided into modes that represent diagnostic reading tasks. Each mode was further broken down into functions supporting that task. Via a data mediator engine, the workstation communicated with clinical data repositories, including the UCLA HIS, Clinical RIS/PACS and individual DICOM compatible scanners. The data mediator served to transparently integrate, retrieve, and cache image and report data. Task-oriented Reading protocols automatically present the appropriate diagnostic information and diagnostic tools to the radiologist. We describe a protocol toolkit that enables the rapid design and implementation of customized reading protocols. We also present an intelligent layer that enables the automatic presentation of the appropriate information. This new methodology for diagnostic workstation design led to an

  5. Advanced beam dynamics and diagnostics concepts for laser-plasma accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Dornmair, Irene

    2017-05-15

    Laser-Plasma Accelerators (LPAs) combine a multitude of unique features, which makes them very attractive as drivers for next generation brilliant light sources including compact X-ray free-electron lasers. They provide high accelerating gradients, thereby drastically shrinking the accelerator size, while at the same time the produced electron bunches are intrinsically as short as a few femtoseconds and carry high peak currents. LPA are subject of very active research, yet, the field currently faces the challenge of improving the beam quality, and achieving stable and well-controlled injection and acceleration. This thesis tackles this issue from three different sides. A novellongitudinal phase space diagnostics is proposed that employs the strong fields present in plasma wakefields to streak ultrashort electron bunches. This allows for a temporal resolution down to the attosecond range, enabling direct determination to the current profile and the slice energy spread, both crucial quantities for the performance of free-electron lasers. Furthermore, adiabatic matching sections at the plasma-vacuum boundary are investigated. These can drastically reduce the beam divergence and thereby relax the constraints on the subsequent beam optics. For externally injected beams, the matching sections could even provide the key technology that permits emittance conservation by increasing the matched beam size to a level achievable with currently available magnetic optics. Finally, a new method is studied that allows to modify the wakefield shape. To this end, the plasma density is periodically modulated. One possible application can be to remove the linearly correlated energy spread, or chirp, from the accelerated bunch, which is suspected of being responsible for the main part of the often large energy spread of plasma accelerated beams.

  6. Application of mid-infrared tuneable diode laser absorption spectroscopy to plasma diagnostics: a review

    Energy Technology Data Exchange (ETDEWEB)

    Roepcke, J [INP-Greifswald, 17489 Greifswald, Friedrich-Ludwig-Jahn-Str. 19 (Germany); Lombardi, G [CNRS LIMHP, Universite Paris XIII, 99, av. J.B. Clement, 93430 Villetaneuse (France); Rousseau, A [Laboratoire de Physique et Technologie des Plasmas, Ecole Polytechnique, CNRS, 91128 Palaiseau (France); Davies, P B [Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW (United Kingdom)

    2006-11-01

    Within the last decade mid-infrared absorption spectroscopy over a region from 3 to 17{mu}m and based on tuneable lead salt diode lasers, often called tuneable diode laser absorption spectroscopy or TDLAS, has progressed considerably as a powerful diagnostic technique for in situ studies of the fundamental physics and chemistry in molecular plasmas. The increasing interest in processing plasmas containing hydrocarbons, fluorocarbons, organo-silicon and boron compounds has led to further applications of TDLAS because most of these compounds and their decomposition products are infrared active. TDLAS provides a means of determining the absolute concentrations of the ground states of stable and transient molecular species, which is of particular importance for the investigation of reaction kinetic phenomena. Information about gas temperature and population densities can also be derived from TDLAS measurements. A variety of free radicals and molecular ions have been detected by TDLAS. Since plasmas with molecular feed gases are used in many applications such as thin film deposition, semiconductor processing, surface activation and cleaning, and materials and waste treatment, this has stimulated the adaptation of infrared spectroscopic techniques to industrial requirements. The recent development of quantum cascade lasers (QCLs) offers an attractive new option for the monitoring and control of industrial plasma processes. The aim of the present paper is threefold: (i) to review recent achievements in our understanding of molecular phenomena in plasmas (ii) to report on selected studies of the spectroscopic properties and kinetic behaviour of radicals and (iii) to describe the current status of advanced instrumentation for TDLAS in the mid-infrared.

  7. Whole Slide Images for primary diagnostics in pathology

    NARCIS (Netherlands)

    Al-Janabi, S.

    2013-01-01

    Whole slide imaging is the process of digitizing glass slides resulting in the creation of Whole Slide Images (WSI). WSI are usually explored with the aid of an image viewer in a manner that closely simulates examining glass slides with a conventional microscope, permitting the manipulation of an

  8. The next generation of electron cyclotron emission imaging diagnostics (invited)

    NARCIS (Netherlands)

    Zhang, P.; Domier, C.W.; Liang, T.; Kong, X.; Tobias, B.; Shen, Z.; N C Luhmann Jr.,; Park, H.; Classen, I.G.J.; van de Pol, M.J.; Donne, A. J. H.; R. Jaspers,

    2008-01-01

    A 128 channel two-dimensional electron cyclotron emission imaging system collects time-resolved 16x8 images of T-e profiles and fluctuations on the TEXTOR tokamak. Electron cyclotron emission imaging (ECEI) is undergoing significant changes which promise to revolutionize and extend its capabilities

  9. The next generation of electron cyclotron emission imaging diagnostics (invited)

    NARCIS (Netherlands)

    Zhang, P.; Domier, C.W.; Liang, T.; Kong, X.; Tobias, B.; Shen, Z.; N C Luhmann Jr.,; Park, H.; Classen, I.G.J.; van de Pol, M.J.; Donne, A. J. H.; R. Jaspers,

    2008-01-01

    A 128 channel two-dimensional electron cyclotron emission imaging system collects time-resolved 16x8 images of T-e profiles and fluctuations on the TEXTOR tokamak. Electron cyclotron emission imaging (ECEI) is undergoing significant changes which promise to revolutionize and extend its capabilities

  10. A Methodology for Anatomic Ultrasound Image Diagnostic Quality Assessment

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Lange, Theis; Brandt, Andreas Hjelm

    2017-01-01

    is valuable in the continuing process of method optimization and guided development of new imaging methods. It includes a three phased study plan covering from initial prototype development to clinical assessment. Recommendations to the clinical assessment protocol, software, and statistical analysis......This paper discusses methods for assessment of ultrasound image quality based on our experiences with evaluating new methods for anatomic imaging. It presents a methodology to ensure a fair assessment between competing imaging methods using clinically relevant evaluations. The methodology...... to properly reveal the clinical value. The paper exemplifies the methodology using recent studies of Synthetic Aperture Sequential Beamforming tissue harmonic imaging....

  11. Magnetic diagnostics: general principles and the problem of reconstruction of plasma current and pressure profiles in toroidal systems

    Energy Technology Data Exchange (ETDEWEB)

    Pustovitov, V.D.

    2000-04-01

    The restrictions of the magnetic diagnostics are discussed. Being related to the integral nature of the measurable quantities, they follow from the fundamental laws of electromagnetism. A series of particular examples demonstrating the strength of these restrictions is given and analyzed. A general rule is emphasized that the information obtained from external magnetic measurements is obviously insufficient for the reliable evaluation of plasma current and pressure profiles in tokamaks or in stellarators. The underlying reason is that outside the plasma the own field of the equilibrium plasma currents is determined by the boundary conditions on the plasma surface only. (author)

  12. WE-AB-206-01: Diagnostic Ultrasound Imaging Quality Assurance.

    Science.gov (United States)

    Zagzebski, J

    2016-06-01

    The involvement of medical physicists in diagnostic ultrasound imaging service is increasing due to QC and accreditation requirements. The goal of this ultrasound hands-on workshop is to demonstrate quality control (QC) testing in diagnostic ultrasound and to provide updates in ACR ultrasound accreditation requirements. The first half of this workshop will include two presentations reviewing diagnostic ultrasound QA/QC and ACR ultrasound accreditation requirements. The second half of the workshop will include live demonstrations of basic QC tests. An array of ultrasound testing phantoms and ultrasound scanners will be available for attendees to learn diagnostic ultrasound QC in a hands-on environment with live demonstrations and on-site instructors. The targeted attendees are medical physicists in diagnostic imaging.

  13. Ion acceleration from intense laser-generated plasma: methods, diagnostics and possible applications

    Directory of Open Access Journals (Sweden)

    Torrisi Lorenzo

    2015-06-01

    Full Text Available Many parameters of non-equilibrium plasma generated by high intensity and fast lasers depend on the pulse intensity and the laser wavelength. In conditions favourable for the target normal sheath acceleration (TNSA regime the ion acceleration from the rear side of the target can be enhanced by increasing the thin foil absorbance through the use of nanoparticles and nanostructures promoting the surface plasmon resonance effect. In conditions favourable for the backward plasma acceleration (BPA regime, when thick targets are used, a special role is played by the laser focal position with respect to the target surface, a proper choice of which may result in induced self-focusing effects and non-linear acceleration enhancement. SiC detectors employed in the time-of-flight (TOF configuration and a Thomson parabola spectrometer permit on-line diagnostics of the ion streams emitted at high kinetic energies. The target composition and geometry, apart from the laser parameters and to the irradiation conditions, allow further control of the plasma characteristics and can be varied by using advanced targets to reach the maximum ion acceleration. Measurements using advanced targets with enhanced the laser absorption effect in thin films are presented. Applications of accelerated ions in the field of ion source, hadrontherapy and nuclear physics are discussed.

  14. Ion Current Collection Diagnostic for the Triggered Plasma Opening Switch Experiment

    Science.gov (United States)

    Jackson, D. P.; Gilmore, M. A.

    2005-10-01

    The novel Triggered Plasma Opening Switch (TPOS) is a unique device that exploits the high conductivity and low mass properties of plasma. The TPOS's objective is to take the initial ˜.8 MA (˜250 ns rise time) storage inductor current and deliver ˜.5 MA at ˜2.5 MV (˜10ns rise time) to a load of ˜5-10 φ. Study of the TPOS characteristics is in progress via an Ion Current Collection Diagnostic (ICCD). The ICCD has been designed, fabricated, tested, and is in use on the TPOS in order to explore the main switch opening profile. The ICCD utilizes 12 charge collectors (biased faraday cups) that are positioned perpendicularly to the main switch stage in order to collect radially traveling ions emitted from the plasma surface via the Child-Langmuir law. Magnetostatic simulations with self consistent space charge emitting surfaces of the main switch using the Trak static 2D finite element code have been conducted as well. Finally, ICCD experimental data have been recorded, and hopefully these data will provide evidence that support both theory and simulation.

  15. Schlieren, Phase-Contrast, and Spectroscopy Diagnostics for the LBNL HIF Plasma Channel Experiment

    Science.gov (United States)

    Ponce, D. M.; Niemann, C.; Fessenden, T. J.; Leemans, W.; Vandersloot, K.; Dahlbacka, G.; Yu, S. S.; Sharp, W. M.; Tauschwitz, A.

    1999-11-01

    The LBNL Plasma Channel experiment has demonstrated stable 42-cm Z-pinch discharge plasma channels with peak currents in excess of 50 kA for a 7 torr nitrogen, 30 kV discharge. These channels offer the possibility of transporting heavy-ion beams for inertial fusion. We postulate that the stability of these channels resides in the existance of a neutral-gas density depresion created by a pre-pulse discharge before the main capacitor bank discharge is created. Here, we present the results and experimental diagnostics setup used for the study of the pre-pulse and main bank channels. Observation of both the plasma and neutral gas dynamics is achieved. Schlieren, Zernike's phase-contrast, and spectroscopic techniques are used. Preliminary Schlieren results show a gas shockwave moving radially at a rate of ≈ 10^6 mm/sec as a result of the fast and localized deposited energy during the evolution of the pre-pulse channel. This data will be used to validate simulation codes (BUCKY and CYCLOPS).

  16. Spectroscropy of middle charge state high-z ions in the ultraviolet for plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Utter, Steven Bryan [Auburn Univ., AL (United States)

    1999-12-11

    The quest for the creation of an economically feasible thermonuclear fusion energy reactor is sttill active after many decades of research. Modern machines produce plasmas which are both hotter and more dense than those created 30 years ago and future devices promise to continue this trend. Paramount to this research is the capability to adequately measure certain parameters of the plasma such as temperature, density, impurity concentration and radiation loss. This dissertation reports three sets of spectroscopic measurements from intermediate charge state of high-Z ions, which have been performed at the Electron Beam Ion Trap (EBIT) facility of the Lawrence Livermore National Laboratory, relevant to the development of spectral plasma diagnostics and to the understanding of radiative energy loss from heavy impurity ions of today's and future fusion devices: measurements of W radiation from 40 - 85 A, precision measurements along the Cu isoelectric sequence, and UV spectroscopy of Ti-like W. The results are also compared to the best available theoretical calculations.

  17. Heavy ion beam probing—diagnostics to study potential and turbulence in toroidal plasmas

    Science.gov (United States)

    Melnikov, A. V.; Krupnik, L. I.; Eliseev, L. G.; Barcala, J. M.; Bravo, A.; Chmyga, A. A.; Deshko, G. N.; Drabinskij, M. A.; Hidalgo, C.; Khabanov, P. O.; Khrebtov, S. M.; Kharchev, N. K.; Komarov, A. D.; Kozachek, A. S.; Lopez, J.; Lysenko, S. E.; Martin, G.; Molinero, A.; de Pablos, J. L.; Soleto, A.; Ufimtsev, M. V.; Zenin, V. N.; Zhezhera, A. I.; T-10 Team; TJ-II Team

    2017-07-01

    Heavy ion beam probing (HIBP) is a unique diagnostics to study the core plasma potential and turbulence. Advanced HIBPs operate in the T-10 tokamak and TJ-II flexible heliac with fine focused (magnetic configurations with ECR and neutral beam injection (NBI) heating at TJ-II. Time evolution of the radial profiles and/or local values of plasma parameters from high field side (HFS) to low field side (LFS), -1  magnetic field B pol (by the beam toroidal shift), poloidal electric filed E pol that allows one to derive the electrostatic turbulent particle flux ΓE×B. The cross-phase of density oscillations produces the phase velocity of their poloidal propagation or rotation; also it gives the poloidal mode number. Dual HIBP, consisting of two identical HIBPs located ¼ torus apart provide the long-range correlations of core plasma parameters. Low-noise high-gain electronics allows us to study broadband turbulence and quasi-coherent modes like geodesic acoustic modes and Alfvén eigenmodes.

  18. Diagnostic imaging of pancreatic diseases. Bildgebende Diagnostik des Pankreas

    Energy Technology Data Exchange (ETDEWEB)

    Claussen, C.D. (Tuebingen Univ. (Germany). Abt. fuer Radiologische Diagnostik)

    1991-12-01

    The review article presents the methods available for diagnostic levaluation of acute and chronic pancreatitis or pancreatic tumors. The most efficient methods are ultrasonography and computed tomography, the latter offering further improvements depending on the case through the application of contrast agents or dynamic examination techniques. Another methods mentioned is the cholangiopancreaticography (ERCP). (GDG).

  19. Optimization of diagnostic imaging use in patients with acute abdominal pain (OPTIMA): Design and rationale

    Science.gov (United States)

    Laméris, Wytze; van Randen, Adrienne; Dijkgraaf, Marcel GW; Bossuyt, Patrick MM; Stoker, Jaap; Boermeester, Marja A

    2007-01-01

    Background The acute abdomen is a frequent entity at the Emergency Department (ED), which usually needs rapid and accurate diagnostic work-up. Diagnostic work-up with imaging can consist of plain X-ray, ultrasonography (US), computed tomography (CT) and even diagnostic laparoscopy. However, no evidence-based guidelines exist in current literature. The actual diagnostic work-up of a patient with acute abdominal pain presenting to the ED varies greatly between hospitals and physicians. The OPTIMA study was designed to provide the evidence base for constructing an optimal diagnostic imaging guideline for patients with acute abdominal pain at the ED. Methods/design Thousand consecutive patients with abdominal pain > 2 hours and < 5 days will be enrolled in this multicentre trial. After clinical history, physical and laboratory examination all patients will undergo a diagnostic imaging protocol, consisting of plain X-ray (upright chest and supine abdomen), US and CT. The reference standard will be a post hoc assignment of the final diagnosis by an expert panel. The focus of the analysis will be on the added value of the imaging modalities over history and clinical examination, relative to the incremental costs. Discussion This study aims to provide the evidence base for the development of a diagnostic algorithm that can act as a guideline for ED physicians to evaluate patients with acute abdominal pain. PMID:17683592

  20. Qualifying plasma diagnostics for a high power microwave background of ECRH heated discharges

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, M.; Baldzuhn, J.; Endler, M.; Laux, M.; Zhang, D.; Laqua, H.P.; Noke, F.; Purps, F.; Ewert, K. [Max-Planck Institut fur Plasmaphysik, EURATOM Association, D-17491 Greifswald (Germany); Oosterbeek, J.W. [Technische Universiteit Eindhoven, Den Doelch 2, 5612 AZ Eindhoven (Netherlands); Jimenez, R. [Associacion EURATOM/CIEMAT, av. Complutense 22, 28040, Madrid (Spain)

    2011-07-01

    Microwave background radiation resulting from multiple reflected unabsorbed ECRH / ECCD power may cause severe problems for microwave absorbing in-vessel components such as gaskets, bellows, windows, isolators and cable insulations in particular during long pulse operation. For qualifying in-vessel components of W7-X in the environment of an isotropic 140 GHz radiation the Microwave Stray Radiation Launch facility, MISTRAL is operated at IPP. Power flux densities of 10-40 kW/m{sup 2} are obtained with a pulsed power gyrotron launching the microwave via a corrugated transmission line and a vacuum window to the MISTRAL vessel. The focus of the program was on cable isolations as required e.g. for in-vessel magnetic diagnostics. Sufficient shielding is obtained in nearly closed metal pipes only. Cryo pumps require a temperature < 12 K where Hydrogen desorption starts. The cryo pumps are usually shielded from plasma radiation by so called chevron structures. It is investigated whether coating of these chevrons with a microwave absorbing layer yields a sufficient reduction of the stray radiation level to ensure cryo pump operation. Diagnostic windows have been tested also. Although the temperature rise even of uncooled ZnSe and quartz windows at 10 kW/m{sup 2} is uncritical with respect to damage the associated refractive index changes may be too high for some diagnostic purposes e.g. for interferometry. A possible shielding are meshes or {mu}W absorbing coatings. Integrated diagnostic mock-ups such as for the diamagnetic loop, the inner Rogowski coils, Mirnov coils and the bolometer head also have been tested

  1. Imaging thermal plasma mass and velocity analyzer

    Science.gov (United States)

    Yau, Andrew W.; Howarth, Andrew

    2016-07-01

    We present the design and principle of operation of the imaging ion mass and velocity analyzer on the Enhanced Polar Outflow Probe (e-POP), which measures low-energy (1-90 eV/e) ion mass composition (1-40 AMU/e) and velocity distributions using a hemispherical electrostatic analyzer (HEA), a time-of-flight (TOF) gate, and a pair of toroidal electrostatic deflectors (TED). The HEA and TOF gate measure the energy-per-charge and azimuth of each detected ion and the ion transit time inside the analyzer, respectively, providing the 2-D velocity distribution of each major ionospheric ion species and resolving the minor ion species under favorable conditions. The TED are in front of the TOF gate and optionally sample ions at different elevation angles up to ±60°, for measurement of 3-D velocity distribution. We present examples of observation data to illustrate the measurement capability of the analyzer, and show the occurrence of enhanced densities of heavy "minor" O++, N+, and molecular ions and intermittent, high-velocity (a few km/s) upward and downward flowing H+ ions in localized regions of the quiet time topside high-latitude ionosphere.

  2. Clinics in diagnostic imaging (58). Chronic cerebral paragonimiasis.

    Science.gov (United States)

    Kaw, G J; Sitoh, Y Y

    2001-02-01

    A 36-year-old Korean man presented with a history of epilepsy. MR imaging of the brain revealed multiple conglomerated round nodules that were hypointense on both T1-and-T2 weighted images. These were located at the left temporal and occipital lobes and had surrounding encephalomalacia. CT scan confirmed the presence of large calcified nodules in the corresponding regions. These imaging findings were typical of chronic cerebral paragonimiasis. The clinical, CT and MR features of cerebral paragonimiasis are reviewed.

  3. Spectroscopic Investigations of Highly Charged Tungsten Ions - Atomic Spectroscopy and Fusion Plasma Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Clementson, Joel [Lund Univ. (Sweden)

    2010-05-01

    The spectra of highly charged tungsten ions have been investigated using x-ray and extreme ultraviolet spectroscopy. These heavy ions are of interest in relativistic atomic structure theory, where high-precision wavelength measurements benchmark theoretical approaches, and in magnetic fusion research, where the ions may serve to diagnose high-temperature plasmas. The work details spectroscopic investigations of highly charged tungsten ions measured at the Livermore electron beam ion trap (EBIT) facility. Here, the EBIT-I and SuperEBIT electron beam ion traps have been employed to create, trap, and excite tungsten ions of M- and L-shell charge states. The emitted spectra have been studied in high resolution using crystal, grating, and x-ray calorimeter spectrometers. In particular, wavelengths of n = 0 M-shell transitions in K-like W55+ through Ne-like W64+, and intershell transitions in Zn-like W44+ through Co-like W47+ have been measured. Special attention is given to the Ni-like W46+ ion, which has two strong electric-dipole forbidden transitions that are of interest for plasma diagnostics. The EBIT measurements are complemented by spectral modeling using the Flexible Atomic Code (FAC), and predictions for tokamak spectra are presented. The L-shell tungsten ions have been studied at electron-beam energies of up to 122 keV and transition energies measured in Ne-like W64+ through Li-like W71+. These spectra constitute the physics basis in the design of the ion-temperature crystal spectrometer for the ITER tokamak. Tungsten particles have furthermore been introduced into the Sustained Spheromak Physics Experiment (SSPX) spheromak in Livermore in order to investigate diagnostic possibilities of extreme ultraviolet tungsten spectra for the ITER divertor. The spheromak measurement and spectral modeling using FAC suggest that tungsten ions in charge states around Er-like W6+ could be useful for

  4. Analytical investigation of microwave resonances of a curling probe for low and high-pressure plasma diagnostics

    Science.gov (United States)

    Arshadi, Ali; Brinkmann, Ralf Peter

    2017-01-01

    The concept of ‘active plasma resonance spectroscopy’ (APRS) has attracted greater interest in recent years as an established plasma diagnostic technique. The APRS describes a class of related methods utilizing the intrinsic ability of plasma to resonate at or near the electron plasma frequency {ω\\text{pe}} . The Curling probe (CP) as a novel realization of the APRS idea, is a miniaturized spiral slot embedded flatly in the chamber wall. Consequently, a plasma diagnostic technique with minimum disturbance and without metal contamination can be developed. To measure the plasma parameters the CP is fed with a weak frequency-swept signal from the exterior of the plasma chamber by a network analyzer which also records the response of the plasma versus the frequency. The resonance behavior is strongly dependent on the electron density and the gas pressure. The CP has also the advantage of resonating at a frequency greater than {ω\\text{pe}} which is dependent on the spiral’s length. The double resonance characteristic gives the CP the ability to be applied in varying plasma regimes. Assuming that the spiralization does not have a considerable effect on the resonances, a ‘straightened’ infinite length CP has recently been investigated (Arshadi and Brinkmann 2016 Plasma Sources Sci. Technol. 25 045014) to obtain the surface wave resonances. This work generalizes the approach and models the CP by a rectangular slot-type resonator located between plasma and quartz. Cold plasma theory and Maxwell’s equations are utilized to compute the electromagnetic fields propagating into the plasma by the diffraction of an incident plane wave at the slot. A mathematical model is employed and both kinds of resonances are derived. The analytical study of this paper shows good agreement with the numerical results of the probe inventors.

  5. MDIS (medical diagnostic imaging support) workstation issues: clinical perspective

    Science.gov (United States)

    Smith, Donald V.; Smith, Suzy; Cawthon, Michael A.

    1991-05-01

    A joint DoD effort is in the final stages of contract acquisition to achieve a ''filmless'' hospital environment in the near future. Success of implementation lays to a large degree on an effective image workstation. This paper will discuss soft copy image display (SCID) of the MDIS system including hardware and software.

  6. Real-time image fusion involving diagnostic ultrasound

    DEFF Research Database (Denmark)

    Ewertsen, Caroline; Săftoiu, Adrian; Gruionu, Lucian G;

    2013-01-01

    The aim of our article is to give an overview of the current and future possibilities of real-time image fusion involving ultrasound. We present a review of the existing English-language peer-reviewed literature assessing this technique, which covers technical solutions (for ultrasound...... and endoscopic ultrasound), image fusion in several anatomic regions, and electromagnetic needle tracking....

  7. Monochromatic X-ray propagation in multi-Z media for imaging and diagnostics including Kα Resonance Fluorescence

    Science.gov (United States)

    Westphal, Maximillian; Lim, Sara; Nahar, Sultana; Pradhan, Anil

    2016-05-01

    Aimed at monochromatic X-ray imaging and therapy, broadband, monochromatic, and quasi-monochromatic X-ray sources and propagation through low and high-Z (HZ) media were studied with numerically and experimentally. Monte Carlo simulations were performed using the software package Geant4, and a new code Photx, to simulate X-ray image contrast, depth of penetration, and total attenuation. The data show that monochromatic and quasi-monochromatic X-rays achieve improved contrast at lower absorbed radiation doses compared to conventional broadband 120 kV or CT scans. Experimental quasi-monochromatic high-intensity laser-produced plasma sources and monochromatic synchrotron beam data are compared. Physical processes responsible for X-ray photoexcitation and absorption are numerically modelled, including a novel mechanism for accelerating Kα resonance fluorescence via twin monochromatic X-ray beam. Potential applications are medical diagnostics and high-Z material detection. Acknowledgement: Ohio Supercomputer Center, Columbus, OH.

  8. Computed Tomography is Diagnostic in the Cervical Imaging of Helmeted Football Players With Shoulder Pads

    Science.gov (United States)

    Rothman, Michael; Foley, Jack; Heller, Michael

    2004-01-01

    Objective: Prospective, observational case series evaluating the value of cervical spine computed tomography (CT) scans in the initial evaluation of a helmeted football player with suspected cervical spine injury. Subjects: Five asymptomatic male football players, fully equipped and immobilized on a backboard. Design: Multiple 3.0-mm, helically acquired, axially displayed CT images of the cervical spine were obtained from the skull base inferiorly through T1, with images filmed at soft tissue and bone windows. Sagittal and coronal reformatted images were performed. Software was used to minimize metallic artifact. Measurements: All series were reviewed by a Board-certified neuroradiologist for image clarity and diagnostic capability. Results: Lateral scout films demonstrated mild segmental degradation, depending on the location of the metallic snaps overlying the spine. Anteroposterior scout films and bone window images were of diagnostic quality. The soft tissue windows showed minimal localized artifact occurring at the same levels as in the lateral scout views. This minimal beam-hardening streak artifact did not affect the diagnostic quality of the soft tissue windows. Reconstructed images were uniformly of clinical diagnostic quality. Discussion: When CT scans were reviewed as a unit, sufficient information was available to allow reliable clinical decisions about the helmeted football player. In light of recent publications demonstrating the difficulty of obtaining adequate radiographs to evaluate cervical spine injury in equipped football players, helmeted athletes may undergo CT scanning without any significant diagnostic limitations. PMID:15496989

  9. [Mass spectrometry analysis of blood plasma lipidome as method of disease diagnostics, evuation of effectiveness and optimization of drug therapy].

    Science.gov (United States)

    Lokhov, P G; Maslov, D L; Balashova, E E; Trifonova, O P; Medvedeva, N V; Torkhovskaya, T I; Ipatova, O M; Archakov, A I; Malyshev, P P; Kukharchuk, V V; Shestakova, E A; Shestakova, M V; Dedov, I I

    2015-01-01

    A new method for the analysis of blood lipid based on direct mass spectrometry of lipophilic low molecular weight fraction of blood plasma has been considered. Such technique allows quantification of hundreds of various types of lipids and this changes existing concepts on diagnostics of lipid disorders and related diseases. The versatility and quickness of the method significantly simplify its wide use. This method is applicable for diagnostics of atherosclerosis, diabetes, cancer and other diseases. Detalization of plasma lipid composition at the molecular level by means of mass spectrometry allows to assess the effectiveness of therapy and to optimize the drug treatment of cardiovascular diseases by phospholipid preparations.

  10. [Diagnostic image management and communication systems: experience at the University of Pisa].

    Science.gov (United States)

    Caramella, D; Del Sarto, M; Bartolozzi, C; Beltrame, F; Sobel, I

    1995-01-01

    Our work was aimed at implementing and validating a system for the acquisition, local management and remote transmission of diagnostic images. Integration of imaging equipment was performed in each of the two sites (5 km apart) in which the Department of Radiology of the University of Pisa is divided. Teleradiology was carried out using 64 Kbit/s lines as well as a 140 Mbit/s Metropolitan Area Network compliant with the Distributed Queue Dual Bus standard. Application domains included remote expert consultation and teleprocessing of diagnostic images. Remote expert consultation was performed in particular by using the 34 Mbit/s interconnection with the Metropolitan Area Network of Florence. Remote processing of diagnostic images using the high speed link allowed the cooperative work with scientific institutions in a field often limited by the complexity of image transfer and by the lack of a timely feed-back concerning the clinical value of processed images. Advanced processing of diagnostic images was performed in the field of stereographic display of CT and MR data sets. Moreover, experience was gained in the visualization, on a single composite image, of the multiparametric data obtained by means of different MR sequences (T1, Spin Density, T2), thus allowing to summarize, by using false colors, different tissue contrast information.

  11. A Methodology for Anatomic Ultrasound Image Diagnostic Quality Assessment.

    Science.gov (United States)

    Hemmsen, Martin Christian; Lange, Theis; Brandt, Andreas Hjelm; Nielsen, Michael Bachmann; Jensen, Jorgen Arendt

    2017-01-01

    This paper discusses the methods for the assessment of ultrasound image quality based on our experiences with evaluating new methods for anatomic imaging. It presents a methodology to ensure a fair assessment between competing imaging methods using clinically relevant evaluations. The methodology is valuable in the continuing process of method optimization and guided development of new imaging methods. It includes a three phased study plan covering from initial prototype development to clinical assessment. Recommendations to the clinical assessment protocol, software, and statistical analysis are presented. Earlier uses of the methodology has shown that it ensures validity of the assessment, as it separates the influences between developer, investigator, and assessor once a research protocol has been established. This separation reduces confounding influences on the result from the developer to properly reveal the clinical value. This paper exemplifies the methodology using recent studies of synthetic aperture sequential beamforming tissue harmonic imaging.

  12. Motion tracking in infrared imaging for quantitative medical diagnostic applications

    Science.gov (United States)

    Cheng, Tze-Yuan; Herman, Cila

    2014-01-01

    In medical applications, infrared (IR) thermography is used to detect and examine the thermal signature of skin abnormalities by quantitatively analyzing skin temperature in steady state conditions or its evolution over time, captured in an image sequence. However, during the image acquisition period, the involuntary movements of the patient are unavoidable, and such movements will undermine the accuracy of temperature measurement for any particular location on the skin. In this study, a tracking approach using a template-based algorithm is proposed, to follow the involuntary motion of the subject in the IR image sequence. The motion tacking will allow to associate a temperature evolution to each spatial location on the body while the body moves relative to the image frame. The affine transformation model is adopted to estimate the motion parameters of the template image. The Lucas-Kanade algorithm is applied to search for the optimized parameters of the affine transformation. A weighting mask is incorporated into the algorithm to ensure its tracking robustness. To evaluate the feasibility of the tracking approach, two sets of IR image sequences with random in-plane motion were tested in our experiments. A steady-state (no heating or cooling) IR image sequence in which the skin temperature is in equilibrium with the environment was considered first. The thermal recovery IR image sequence, acquired when the skin is recovering from 60-s cooling, was the second case analyzed. By proper selection of the template image along with template update, satisfactory tracking results were obtained for both IR image sequences. The achieved tracking accuracies are promising in terms of satisfying the demands imposed by clinical applications of IR thermography.

  13. Diagnostics

    DEFF Research Database (Denmark)

    Donné, A.J.H.; Costley, A.E.; Barnsley, R.

    2007-01-01

    In order to support the operation of ITER and the planned experimental programme an extensive set of plasma and first wall measurements will be required. The number and type of required measurements will be similar to those made on the present-day large tokamaks while the specification of the mea...

  14. Child abuse. Diagnostic imaging of skeletal injuries; Kindesmisshandlung. Radiologische Diagnostik skelettaler Verletzungsfolgen

    Energy Technology Data Exchange (ETDEWEB)

    Stenzel, Martin; Mentzel, Hans-Joachim [Universitaetsklinikum Jena (Germany). Sektion Paediatrische Radiologie

    2012-06-15

    Diagnostic imaging, besides medical history and clinical examination, is a major component in assessment of cases of suspected physical child abuse. Performance of proper imaging technique, and knowledge of specific injury patterns is required for accurate image interpretation by the radiologist, and serves protection of the child in case of proven abuse. On the other side, it is essential to protect the family in unjustified accusations. The reader will be familiarised with essentials of the topic 'Physical child abuse', in order to be able to correctly assess quality, completeness, and results of X-ray films. Moreover, opportunities and limitations of alternative diagnostic modalities will be discussed. (orig.)

  15. First Steps Toward Incorporating Image Based Diagnostics Into Particle Accelerator Control Systems Using Convolutional Neural Networks

    Energy Technology Data Exchange (ETDEWEB)

    Edelen, A. L.; Biedron, S. G.; Milton, S. V.; Edelen, J. P.

    2016-12-16

    At present, a variety of image-based diagnostics are used in particle accelerator systems. Often times, these are viewed by a human operator who then makes appropriate adjustments to the machine. Given recent advances in using convolutional neural networks (CNNs) for image processing, it should be possible to use image diagnostics directly in control routines (NN-based or otherwise). This is especially appealing for non-intercepting diagnostics that could run continuously during beam operation. Here, we show results of a first step toward implementing such a controller: our trained CNN can predict multiple simulated downstream beam parameters at the Fermilab Accelerator Science and Technology (FAST) facility's low energy beamline using simulated virtual cathode laser images, gun phases, and solenoid strengths.

  16. X-ray calibration facility for plasma diagnostics of the MégaJoule laser

    Directory of Open Access Journals (Sweden)

    Hubert S.

    2013-11-01

    Full Text Available The Laser MégaJoule (LMJ located at CEA-CESTA will be equipped with x-ray plasma diagnostics using different kinds of x-ray components such as filters, mirrors, crystals, detectors and cameras. To guarantee LMJ measurements, detectors such as x-ray cameras need to be regularly calibrated. An x-ray laboratory is devoted to this task and performs absolute x-ray calibrations for similar x-ray cameras running on Laser Integration Line (LIL. This paper presents the x-ray calibration bench with its x-ray tube based High Energy x-ray Source (HEXS and some calibration results. By mean of an ingenious transposition system under vacuum absolute x-ray calibration of x-ray cameras, like streak and stripline ones, can be carried out. Coupled to a new collimation system with micrometric accuracy on aperture sensitivity quantum efficiency measurements can be achieved with reduced uncertainties.

  17. Single-crystal Diamond Detector for DT and DD plasmas diagnostic

    Science.gov (United States)

    Rebai, M.; Cazzaniga, C.; Tardocchi, M.; Grosso, G.; Croci, G.; Perelli Cippo, E.; Calvani, P.; Girolami, M.; Trucchi, D. M.; Gorini, G.

    2016-11-01

    Single-crystal Diamond Detectors (SDD) are good candidates as high-energy neutron detectors in the extreme conditions of the next generation thermonuclear fusion facilities like the ITER experiment, due to their high radiation hardness, fast response time and small size. Neutron detection in SDDs is based on the collection of electron-hole pairs produced by charged particles generated by neutron interaction on 12 C . In this work the SDD response to neutrons with energies between 2.8 and 3.8MeV was determined at the Legnaro CN accelerator at the INFN Laboratories in Legnaro (PD, Italy). This work is relevant for the characterization of SDDs response functions, which are key points for Deuterium-Deuterium and Deuterium-Tritium plasma diagnostic.

  18. Necrotizing fasciitis: contribution and limitations of diagnostic imaging.

    Science.gov (United States)

    Malghem, Jacques; Lecouvet, Frédéric E; Omoumi, Patrick; Maldague, Baudouin E; Vande Berg, Bruno C

    2013-03-01

    Necrotizing fasciitis is a rare, rapidly spreading, deep-seated infection causing thrombosis of the blood vessels located in the fascia. Necrotizing fasciitis is a surgical emergency. The diagnosis typically relies on clinical findings of severe sepsis and intense pain, although subacute forms may be difficult to recognize. Imaging studies can help to differentiate necrotizing fasciitis from infections located more superficially (dermohypodermitis). The presence of gas within the necrotized fasciae is characteristic but may be lacking. The main finding is thickening of the deep fasciae due to fluid accumulation and reactive hyperemia, which can be visualized using computed tomography and, above all, magnetic resonance imaging (high signal on contrast-enhanced T1 images and T2 images, best seen with fat saturation). These findings lack specificity, as they can be seen in non-necrotizing fasciitis and even in non-inflammatory conditions. Signs that support a diagnosis of necrotizing fasciitis include extensive involvement of the deep intermuscular fascias (high sensitivity but low specificity), thickening to more than 3mm, and partial or complete absence on post-gadolinium images of signal enhancement of the thickened fasciae (fairly high sensitivity and specificity). Ultrasonography is not recommended in adults, as the infiltration of the hypodermis blocks ultrasound transmission. Thus, imaging studies in patients with necrotizing fasciitis may be challenging to interpret. Although imaging may help to confirm deep tissue involvement and to evaluate lesion spread, it should never delay emergency surgical treatment in patients with established necrotizing fasciitis.

  19. An imaging proton spectrometer for short-pulse laser plasma experiments

    Energy Technology Data Exchange (ETDEWEB)

    Chen, H; Hazi, A; van Maren, R; Chen, S; Fuchs, J; Gauthier, M; Pape, S L; Rygg, J R; Shepherd, R

    2010-05-11

    Ultra intense short pulse laser pulses incident on solid targets can generate energetic protons. In additions to their potentially important applications such as in cancer treatments and proton fast ignition, these protons are essential to understand the complex physics of intense laser plasma interaction. To better characterize these laser-produced protons, we designed and constructed a novel, spatially imaging proton spectrometer that will not only measure proton energy distribution with high resolution, but also provide its angular characteristics. The information obtained from this spectrometer compliments those from commonly used diagnostics including radiochromic film packs, CR39 nuclear track detectors, and non-imaging magnetic spectrometers. The basic characterizations and sample data from this instrument are presented.

  20. Advanced radiation measurement techniques in diagnostic radiology and molecular imaging.

    Science.gov (United States)

    Del Guerra, Alberto; Belcari, Nicola; Llacer, Gabriela Llosa; Marcatili, Sara; Moehrs, Sascha; Panetta, Daniele

    2008-01-01

    This paper reports some technological advances recently achieved in the fields of micro-CT and small animal PET instrumentation. It highlights a balance between image-quality improvement and dose reduction. Most of the recent accomplishments in these fields are due to the use of novel imaging sensors such as CMOS-based X-ray detectors and silicon photomultipliers (SiPM). Some of the research projects carried out at the University of Pisa for the development of such advanced radiation imaging technology are also described.

  1. Spectroscopic diagnostics of electron temperature and energy conversion efficiency of laser-sustained plasma in flowing argon

    Science.gov (United States)

    Mazumder, J.; Krier, H.; Chen, X.

    1988-08-01

    Laser sustained plasmas are often formed during laser materials interaction. The University's 10 kW CW CO2 laser has been used to study argon plasmas for the application to laser supported propulsion and laser materials processing. The spectroscopic diagnostic method has been applied to study laser-sustained plasmas in 1 atmosphere pure argon gas flow with an f/7 on-axis laser focusing scheme. High flow speeds of 2 to 10 m/sec are achieved. Plasma electron temperatures distributions are determined from the 415.8 nm Ar1 line and its adjacent continuum intensities. Plasma core temperatures as high as 20,000 K are reported. The total absorption of the incident laser power and the radiation loss by the plasma are calculated from the temperature distribution. Results indicated that up to 86 percent of the incident laser power can be absorbed and nearly 60 percent of the incident laser power can be retained by the flowing argon gas to provide thrust. Further research is called for in the Laser Induced Fluorescence (LIF) technique for diagnostics of the downstream mixing zone and the plasma outer region. Experiments over a wider range of operating conditions, as well as multiple plasma testings, are required to find the optimum operating scheme.

  2. Nanoscale imaging using a compact laser plasma EUV source

    Science.gov (United States)

    Wachulak, Przemyslaw; Bartnik, Andrzej; Fiedorowicz, Henryk; Kostecki, Jerzy; Jarocki, Roman; Szczurek, Miroslaw; Szczurek, Anna; Feigl, Torsten; Pina, Ladislav

    2012-05-01

    High resolution imaging methods and techniques are currently under development. One of them is an extreme ultraviolet (EUV) microscopy, based on Fresnel zone plates. In this paper a compact, high-repetition, laser-plasma EUV source, emitting quasi-monochromatic radiation at 13.8nm wavelength was used in a desktop EUV transmission microscopy with a spatial (half-pitch) resolution of 50nm. EUV microscopy images of objects with various thicknesses and the spatial resolution measurements using the knife-edge test are presented.

  3. Application of a three-dimensional display in diagnostic imaging.

    Science.gov (United States)

    Baxter, B; Hitchner, L E; Anderson, R E

    1982-10-01

    An autostereoscopic viewing device for tomographic scans that allows a physician to examine multiple computed tomography sections with each section properly positioned in three dimensions has been constructed and tested. Images produced on the device allow the observer to utilize both motion parallax and stereoscopic depth cues as if viewing a real three-dimensional (3D) object. These 3D images can be very striking because of the ease with which one can form a true impression of depth relationships. We describe operating principles of the viewing device and the appearance of images produced on it. Stereo photographs made from 3D images displayed on the device are included to illustrate potential applications and problems.

  4. Data Acquisition and Automation for Plasma Rotation Diagnostic in the TCABR Tokamak

    Science.gov (United States)

    Ronchi, G.; Severo, J. H. F.; de Sá, W. P.; Galvão, R. M. O.

    2015-03-01

    In this work we describe the implementation of a full modular system of data acquisition and processing for the plasma rotation diagnostic in the TCABR tokamak. The experimental setup uses a single monochromator and six photomultipliers (PMT), in which pair of PMTs measures the light at slightly different wavelengths. Thus, it can measure the time evolution of the Doppler shift of the impurities emission lines coming from three spatial positions (one for toroidal rotation and two for poloidal rotation). The data acquisition and preanalysis program were written with LabVIEW software and is capable of controlling the spectrometer wavelength, PMTs power supplies, data acquisition, and storage. All data are recorded in MDSplus trees that easily allow data visualization and post-processing analysis (both locally and remotely) via MATLAB, Python, Java and others programming languages. This system can run independently from other diagnostics and machine systems and can be integrated with the main tokamak control system by means of TCP/IP messages.

  5. Concerted spatial-frequency and polarization-phase filtering of laser images of polycrystalline networks of blood plasma smears

    Science.gov (United States)

    Ushenko, Yu A.

    2012-11-01

    The complex technique of concerted polarization-phase and spatial-frequency filtering of blood plasma laser images is suggested. The possibility of obtaining the coordinate distributions of phases of linearly and circularly birefringent protein networks of blood plasma separately is presented. The statistical (moments of the first to fourth orders) and scale self-similar (logarithmic dependences of power spectra) structure of phase maps of different types of birefringence of blood plasma of two groups of patients-healthy people (donors) and those suffering from rectal cancer-is investigated. The diagnostically sensitive parameters of a pathological change of the birefringence of blood plasma polycrystalline networks are determined. The effectiveness of this technique for detecting change in birefringence in the smears of other biological fluids in diagnosing the appearance of cholelithiasis (bile), operative differentiation of the acute and gangrenous appendicitis (exudate), and differentiation of inflammatory diseases of joints (synovial fluid) is shown.

  6. [Adrenal tumors: principles of imaging and differential diagnostics].

    Science.gov (United States)

    Degenhart, C

    2014-10-01

    Adrenal masses are very common and are usually detected incidentally. Less frequently, imaging is performed for the localization of the underlying lesion in the case of endocrine disease. The differentiation between adenomas and non-adenomas is fundamental. Adenomas show a low density on unenhanced computed tomography (CT) and a rapid washout of contrast agents. In magnetic resonance imaging (MRI) adenomas are characterized by a low signal in opposed phase imaging as compared to in phase imaging. According to the literature a density of less than 10 HU in an adrenal mass has a specificity of 98% and a sensitivity of 71% for the presence of an adenoma and MRI is slightly more sensitive. Some adrenal lesions, e.g. cysts or myelolipomas can be diagnosed with high accuracy due to pathognomonic findings. In the majority of cases the synopsis of imaging along with clinical and laboratory findings is necessary for a reliable diagnosis. For the evaluation of an adrenal mass the CT examination should begin with an unenhanced scan, if necessary followed by a washout examination. In the case of MRI in phase and opposed phase imaging are essential components of the examination.

  7. Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa

    Science.gov (United States)

    Näsström, Elin; Parry, Christopher M; Vu Thieu, Nga Tran; Maude, Rapeephan R; de Jong, Hanna K; Fukushima, Masako; Rzhepishevska, Olena; Marks, Florian; Panzner, Ursula; Im, Justin; Jeon, Hyonjin; Park, Seeun; Chaudhury, Zabeen; Ghose, Aniruddha; Samad, Rasheda; Van, Tan Trinh; Johansson, Anders; Dondorp, Arjen M; Thwaites, Guy E; Faiz, Abul; Antti, Henrik; Baker, Stephen

    2017-01-01

    Salmonella Typhi is the causative agent of typhoid. Typhoid is diagnosed by blood culture, a method that lacks sensitivity, portability and speed. We have previously shown that specific metabolomic profiles can be detected in the blood of typhoid patients from Nepal (Näsström et al., 2014). Here, we performed mass spectrometry on plasma from Bangladeshi and Senegalese patients with culture confirmed typhoid fever, clinically suspected typhoid, and other febrile diseases including malaria. After applying supervised pattern recognition modelling, we could significantly distinguish metabolite profiles in plasma from the culture confirmed typhoid patients. After comparing the direction of change and degree of multivariate significance, we identified 24 metabolites that were consistently up- or down regulated in a further Bangladeshi/Senegalese validation cohort, and the Nepali cohort from our previous work. We have identified and validated a metabolite panel that can distinguish typhoid from other febrile diseases, providing a new approach for typhoid diagnostics. DOI: http://dx.doi.org/10.7554/eLife.15651.001 PMID:28483042

  8. Experimental and theoretical research in applied plasma physics

    Energy Technology Data Exchange (ETDEWEB)

    Porkolab, M.

    1992-01-01

    This report discusses research in the following areas: fusion theory and computations; theory of thermonuclear plasmas; user service center; high poloidal beta studies on PBX-M; fast ECE fluctuation diagnostic for balloning mode studies; x-ray imaging diagnostic; millimeter/submillimeter-wave fusion ion diagnostics; small scale turbulence and nonlinear dynamics in plasmas; plasma turbulence and transport; phase contrast interferometer diagnostic for long wavelength fluctuations in DIII-D; and charged and neutral fusion production for fusio plasmas.

  9. Resonant scattering as a sensitive diagnostic of current collisional plasma models

    Science.gov (United States)

    Ogorzalek, Anna; Zhuravleva, Irina; Allen, Steven W.; Pinto, Ciro; Werner, Norbert; Mantz, Adam; Canning, Rebecca; Fabian, Andrew C.; Kaastra, Jelle S.; de Plaa, Jelle

    2017-08-01

    Resonant scattering is a subtle process that suppresses fluxes of some of the brightest optically thick X-ray emission lines produced by collisional plasmas in galaxy clusters and massive early-type galaxies. The amplitude of the effect depends on the turbulent structure of the hot gas, making it a sensitive velocity probe. It is therefore crucial to properly model this effect in order to correctly interpret high resolution X-ray spectra. Our measurements of resonant scattering with XMM-Newton Reflection Grating Spectrometer in giant elliptical galaxies and with Hitomi in the center of Perseus Cluster show that the potentially rich inference from this effect is limited by the uncertainties in the atomic data underlying plasma codes such as APEC and SPEX. Typically, the effect is of the order of 10-20%, while the discrepancy between the two codes is of similar order or even higher. Precise knowledge of the emissivity and oscillator strengths of lines emitted by Fe XVII and Fe XXV, as well as their respective uncertainties propagated through plasma codes are key to understanding gas dynamics and microphysics in giant galaxies and cluster ICM, respectively. This is especially crucial for massive ellipticals, where sub-eV resolution would be needed to measure line broadening precisely, making resonant scattering an important velocity diagnostic in these systems for the foreseeable future. In this poster, I will summarize current status of resonant scattering measurements and show how they depend on the assumed atomic data. I will also discuss which improvements are essential to maximize scientific inference from future high resolution X-ray spectra.

  10. Reliability of measuring pelvic floor elevation with a diagnostic ultrasonic imaging device

    OpenAIRE

    Ubukata, Hitomi; Maruyama, Hitoshi; Huo, Ming

    2015-01-01

    [Purpose] The purpose of this study was to investigate the reliability of measuring the amount of pelvic floor elevation during pelvic and abdominal muscle contraction with a diagnostic ultrasonic imaging device. [Subjects] The study group comprised 11 healthy women without urinary incontinence or previous birth experience. [Methods] We measured the displacement elevation of the bladder base during contraction of the abdominal and pelvic floor muscles was measured using a diagnostic ultrasoni...

  11. Microwave-heating-coupled photoacoustic radar for tissue diagnostic imaging

    Science.gov (United States)

    Wang, Wei; Mandelis, Andreas

    2016-06-01

    An investigation of microwave (MW) heating effects on biotissue for enhancing photoacoustic radar (PAR) signals was conducted. Localized tissue heating generated by MWs was used to improve PAR imaging depth and signal-to-noise ratio (SNR). Elevated temperatures were measured with thermocouples in ex vivo bovine muscle. The measured temperature rise on the heated spot surface by MWs was in agreement with theoretical predictions. The study showed localized MW heating can increase the photoacoustic imaging depth by 11%, and the SNR by 5% in ex vivo bovine muscle.

  12. Radiation exposure and image quality in x-Ray diagnostic radiology physical principles and clinical applications

    CERN Document Server

    Aichinger, Horst; Joite-Barfuß, Sigrid; Säbel, Manfred

    2012-01-01

    The largest contribution to radiation exposure to the population as a whole arises from diagnostic X-rays. Protecting the patient from radiation is a major aim of modern health policy, and an understanding of the relationship between radiation dose and image quality is of pivotal importance in optimising medical diagnostic radiology. In this volume the data provided for exploring these concerns are partly based on X-ray spectra, measured on diagnostic X-ray tube assemblies, and are supplemented by the results of measurements on phantoms and simulation calculations.

  13. High resolution X-ray spherically bent crystal spectrometer for laser-produced plasma diagnostics

    Institute of Scientific and Technical Information of China (English)

    Shali Xiao; Hongjian Wang; Jun Shi; Changhuan Tang; Shenye Liu

    2009-01-01

    A new high spectral resolution crystal spectrometer is designed to measure very low emissive X-ray spectra of laser-produced plasma in 0.5 - 0.9 nm range. A large open aperture (30 x 20 (mm)) mica (002) spherically bent crystal with curvature radius R = 380 mm is used as dispersive and focusing element. The imaging plate is employed to obtain high spectral resolution with effective area of 30 x 80 (mm). The long designed path of the X-ray spectrometer beam is 980 mm from the source to the detector via the crystal. Experiment is carried out at a 20-J laser facility. X-ray spectra in an absolute intensity scale is obtained from Al laser produced plasmas created by laser energy of 6.78 J. Samples of spectra obtained with spectral resolution of up to E/鈻矱 ~ 1500 are presented. The results clearly show that the device is good to diagnose laser high-density plasmas.

  14. Imaging methods for knee-joint diagnostics. Bildgebende Verfahren zur Diagnostik von Kniegelenksverletzungen und -erkrankungen

    Energy Technology Data Exchange (ETDEWEB)

    Haller, W. (Klinikum rechts der Isar, Muenchen (Germany, F.R.). Orthopaedische Klinik und Poliklinik); Lehner, K. (Klinikum rechts der Isar, Muenchen (Germany, F.R.). Inst. fuer Roentgendiagnostik)

    1989-06-01

    Imaging methods are essential tools for orthopedic diagnostics. For examination of knee-joint disorder, X-ray radiography in four planes is a standard task. Special diagnostic methods are available and can be selected according to the case, and sonography is a method very likely to gain significance. In case of suspected fracture, conventional tomography is the method of choice, although arthroscopy is discussed in this context as a primary examination. CT or NMR imaging are indicated for evaluation of tumors near the knee joint, and latest results show that magnetic resonance tomography is useful for examination of the cruciate ligaments or the cartilage, and CT for imaging of the menisci. CT assisted arthrography for sliding path and cartilage analysis already is an established method for diagnostic evaluation of the chondropathia patellae. (orig./MG).

  15. Optical boundary reconstruction of tokamak plasmas for feedback control of plasma position and shape

    NARCIS (Netherlands)

    Hommen, G.; de M. Baar,; Nuij, P.; McArdle, G.; Akers, R.; Steinbuch, M.

    2010-01-01

    A new diagnostic is developed to reconstruct the plasma boundary using visible wavelength images. Exploiting the plasma's edge localized and toroidally symmetric emission profile, a new coordinate transform is presented to reconstruct the plasma boundary from a poloidal view image. The plasma b

  16. Application and Continued Development of Thin Faraday Collectors as a Lost Ion Diagnostic for Tokamak Fusion Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    F. Ed Cecil

    2011-06-30

    This report summarizes the accomplishment of sixteen years of work toward the development of thin foil Faraday collectors as a lost energetic ion diagnostic for high temperature magnetic confinement fusion plasmas. Following initial, proof of principle accelerator based studies, devices have been tested on TFTR, NSTX, ALCATOR, DIII-D, and JET (KA-1 and KA-2). The reference numbers refer to the attached list of publications. The JET diagnostic KA-2 continues in operation and hopefully will provide valuable diagnostic information during a possible d-t campaign on JET in the coming years. A thin Faraday foil spectrometer, by virtue of its radiation hardness, may likewise provide a solution to the very challenging problem of lost alpha particle measurements on ITER and other future burning plasma machines.

  17. Three-dimensional imaging of acetabular dysplasia: diagnostic value and impact on surgical type classification

    Energy Technology Data Exchange (ETDEWEB)

    Smet, Maria-Helena E-mail: marleen.smet@uz.kuleuven.ac.be; Marchal, Guy J.; Baert, Albert L.; Hoe, Lieven van; Cleynenbreugel, Johan van; Daniels, Hans; Molenaers, Guy; Moens, Pierre; Fabry, Guy

    2000-04-01

    Objective: To investigate the diagnostic value and the impact on surgical type classification of three-dimensional (3D) images for pre-surgical evaluation of dysplastic hips. Materials and methods: Three children with a different surgical type of hip dysplasia were investigated with helical computed tomography. For each patient, two-dimensional (2D) images, 3D, and a stereolithographic model of the dysplastic hip were generated. In two separate sessions, 40 medical observers independently analyzed the 2D images (session 1), the 2D and 3D images (session 2), and tried to identify the corresponding stereolithographic hip model. The influence of both image presentation (2D versus 3D images) and observer (degree of experience, radiologist versus orthopedic surgeon) were statistically analyzed. The SL model choice reflected the impact on surgical type classification. Results: Image presentation was a significant factor whereas the individual observer was not. Three-dimensional images scored significantly better than 2D images (P=0.0003). Three-dimensional imaging increased the correct surgical type classification by 35%. Conclusion: Three-dimensional images significantly improve the pre-surgical diagnostic assessment and surgical type classification of dysplastic hips.

  18. Image quality and diagnostic performance of free-breathing diffusion-weighted imaging for hepatocellular carcinoma.

    Science.gov (United States)

    Takayama, Yukihisa; Nishie, Akihiro; Asayama, Yoshiki; Ishigami, Kousei; Kakihara, Daisuke; Ushijima, Yasuhiro; Fujita, Nobuhiro; Shirabe, Ken; Takemura, Atsushi; Honda, Hiroshi

    2017-05-18

    To retrospectively evaluate the diagnostic performance of free-breathing diffusion-weighted imaging (FB-DWI) with modified imaging parameter settings for detecting hepatocellular carcinomas (HCCs). Fifty-one patients at risk for HCC were scanned with both FB-DWI and respiratory-triggered DWI with the navigator echo respiratory-triggering technique (RT-DWI). Qualitatively, the sharpness of the liver contour, the image noise and the chemical shift artifacts on each DWI with b-values of 1000 s/mm(2) were independently evaluated by three radiologists using 4-point scoring. We compared the image quality scores of each observer between the two DWI methods, using the Wilcoxon signed-rank test. Quantitatively, we compared the signal-to-noise ratios (SNRs) of the liver parenchyma and lesion-to-nonlesion contrast-to-noise ratios (CNRs) after measuring the signal intensity on each DWI with a b-factor of 1000 s/mm(2). The average SNRs and CNRs between the two DWI methods were compared by the paired t-test. The detectability of HCC on each DWI was also analyzed by three radiologists. The detectability provided by the two DWI methods was compared using McNemar's test. For all observers, the averaged image quality scores of FB-DWI were: Sharpness of the liver contour [observer (Obs)-1, 3.08 ± 0.81; Obs-2, 2.98 ± 0.73; Obs-3, 3.54 ± 0.75], those of the distortion (Obs-1, 2.94 ± 0.50; Obs-2, 2.71 ± 0.70; Obs-3, 3.27 ± 0.53), and the chemical shift artifacts (Obs-1, 3.38 ± 0.60; Obs-2, 3.15 ± 1.07; Obs-3, 3.21 ± 0.85). The averaged image quality scores of RT-DWI were: Sharpness of the liver contour (Obs-1, 2.33 ± 0.65; Obs-2, 2.37 ± 0.74; Obs-3, 2.75 ± 0.81), distortion (Obs-1, 2.81 ± 0.56; Obs-2, 2.25 ± 0.74; Obs-3, 2.96 ± 0.71), and the chemical shift artifacts (Obs-1, 2.92 ± 0.59; Obs-2, 2.21 ± 0.85; Obs-3, 2.77 ± 1.08). All image quality scores of FB-DWI were significantly higher than those of RT-DWI (P quality and higher detectability of HCC compared to RT

  19. An in situ accelerator-based diagnostic for plasma-material interactions science on magnetic fusion devices

    Science.gov (United States)

    Hartwig, Zachary S.; Barnard, Harold S.; Lanza, Richard C.; Sorbom, Brandon N.; Stahle, Peter W.; Whyte, Dennis G.

    2013-12-01

    This paper presents a novel particle accelerator-based diagnostic that nondestructively measures the evolution of material surface compositions inside magnetic fusion devices. The diagnostic's purpose is to contribute to an integrated understanding of plasma-material interactions in magnetic fusion, which is severely hindered by a dearth of in situ material surface diagnosis. The diagnostic aims to remotely generate isotopic concentration maps on a plasma shot-to-shot timescale that cover a large fraction of the plasma-facing surface inside of a magnetic fusion device without the need for vacuum breaks or physical access to the material surfaces. Our instrument uses a compact (˜1 m), high-current (˜1 milliamp) radio-frequency quadrupole accelerator to inject 0.9 MeV deuterons into the Alcator C-Mod tokamak at MIT. We control the tokamak magnetic fields - in between plasma shots - to steer the deuterons to material surfaces where the deuterons cause high-Q nuclear reactions with low-Z isotopes ˜5 μm into the material. The induced neutrons and gamma rays are measured with scintillation detectors; energy spectra analysis provides quantitative reconstruction of surface compositions. An overview of the diagnostic technique, known as accelerator-based in situ materials surveillance (AIMS), and the first AIMS diagnostic on the Alcator C-Mod tokamak is given. Experimental validation is shown to demonstrate that an optimized deuteron beam is injected into the tokamak, that low-Z isotopes such as deuterium and boron can be quantified on the material surfaces, and that magnetic steering provides access to different measurement locations. The first AIMS analysis, which measures the relative change in deuterium at a single surface location at the end of the Alcator C-Mod FY2012 plasma campaign, is also presented.

  20. PREFACE: Fourteenth International Symposium on Laser-Aided Plasma Diagnostics (LAPD14)

    Science.gov (United States)

    Giudicotti, L.; Pasqualotto, R.

    2010-04-01

    The attached PDF contains, the full preface, a list of the scientific committee, former LAPD chairmen, local organizers, previous locations of LAPD meetings, participants email contacts and a list of the contributed papers. logo The Fourteenth International Symposium on Laser-Aided Plasma Diagnostics (LAPD14), was held from 21-24 September 2009 in Castelbrando, Treviso, Italy. The series of LAPD symposia was originally started at Kyushu University in 1983, and since then it has been organized every two years alternately in Japan, Europe and the United States, traveling around the world five times. Each LAPD Symposium brings together scientists working in different disciplines all related to the diagnostics of any type of plasma by laser or similar techniques. Researchers working on nuclear fusion, industrial process, low temperature plasma chemistry, laser development and material science, are invited to present prominent new diagnostic developments, with the aim of synergetic discussions. The broad spectrum of contributions represents one of the strengths of this symposium, which is an important, unique and fruitful source of cross-fertilization between these fields and a forum of discussions. The scope of LAPD14 was very broad, including many techniques related to laser probing of plasmas: incoherent and coherent Thomson scattering, polarimetry, interferometry, reflectometry, laser induced fluorescence, laser absorption spectroscopy, laser photodetachment spectroscopy, cavity ringdown spectroscopy, Raman scattering, reflectometry, microwave diagnostics and related laser and hardware developments. LAPD14 was attended by 66 researchers, from 15 different countries who presented a total of 57 papers (13 general, 12 topical, 10 short talks and 23 poster contributions). It is a tradition of LAPD that the first lecture of each meeting, which is more general and aims to review prominent new developments, is called 'the Akazaki lecture' in honor of Professor Masanori

  1. Radiation Dose Risk and Diagnostic Benefit in Imaging Investigations

    CERN Document Server

    Dobrescu, Lidia

    2015-01-01

    The paper presents many facets of medical imaging investigations radiological risks. The total volume of prescribed medical investigations proves a serious lack in monitoring and tracking of the cumulative radiation doses in many health services. Modern radiological investigations equipment is continuously reducing the total dose of radiation due to improved technologies, so a decrease in per caput dose can be noticed, but the increasing number of investigations has determined a net increase of the annual collective dose. High doses of radiation are cumulated from Computed Tomography investigations. An integrated system for radiation safety of the patients investigated by radiological imaging methods, based on smart cards and Public Key Infrastructure allow radiation absorbed dose data storage.

  2. Cardiac diagnostic imaging; Bildgebende Verfahren in der Diagnostik des Herzens

    Energy Technology Data Exchange (ETDEWEB)

    Knez, A.; Becker, A.; Leber, A.; Haberl, R.; Steinbeck, G. [Klinikum Grosshadern, Muenchen (Germany). Medizinische Klinik 1; Becker, C.; Reiser, M. [Klinikum Grosshadern, Muenchen (Germany). Inst. fuer Klinische Radiologie

    2000-02-01

    Purpose: Cardiac imaging includes determination of the size and structure of the cardiac chambers, valves, great vessels and the coronary arteries, chamber and valvular function, myocardial perfusion, viability and metabolism. Material and methods: Chest roentgenography, angiography, echocardiography and nuclear imaging are commonly used but computed tomography and magnetic resonance imaging also offer a promising potential. Results: Coronary angiography is the gold standard in assessing coronary anatomy. Fast CT technologies such as electron-beam and multi-row-CT are promising non-invasive imaging modalities in the assessment of coronary artery disease. With intravascular ultrasound early stages of coronary atherosclerosis can be detected. For the assessment of myocardial perfusion and viability as well as cardiac function, scintigraphic methods are widely accepted. However, MRI methods have also reached a high degree of accuracy. Evaluation of chamber and valvular function is, due to its wide availability, the field of echocardiography. (orig.) [German] Zielsetzung: Anforderungen an die kardiale Bildgebung sind die Darstellung der Anatomie der Herzhoehlen, Herzklappen, Koronararterien und der grossen Gefaesse, Parameter der Ventrikel- und Klappenfunktion, der Myokardperfusion, Myokardvitalitaet und des myokardialen Stoffwechsels. Material und Methode: In der Bildgebung kommen neben den etablierten Standardverfahren wie Roentgen, Angiographie, Echokardiographie und nuklearmedizinischen Methoden auch neuere Verfahren der Computer- und Magnetresonanztomographie zum Einsatz. Ergebnisse: Die Koronarangiographie ist der Goldstandard in der Darstellung des gesamten Koronarsystems. In der Diagnostik der koronaren Herzerkrankung zeigen schnelle CT-Verfahren wie die Elektronenstrahltomographie (EBT) und die Mehrzeilendetektor-CT (MDCT) Vorteile gegenueber der Kernspintomographie. Fruehstadien der koronaren Arteriosklerose koennen nur mit dem intravaskulaeren Ultraschall

  3. Clinics in diagnostic imaging (82). Lesser trochanter metastasis.

    Science.gov (United States)

    Peh, W C G; Muttarak, M

    2003-02-01

    A 73-year-old woman who had previous mastectomy for breast carcinoma presented with persistent pain over the left hip area for two to three months. Pelvic radiograph showed an expanded osteolytic lesion involving the lesser trochanter of the left femur, with adjacent ill-defined destructive changes. She subsequently developed a displaced pathological fracture through the lesser trochanteric metastasis. The clinical features and pathophysiology of bone metastases are discussed. The role of imaging, with additional illustrative examples, is emphasised.

  4. Tuberous sclerosis complex: Diagnostic role of magnetic resonance imaging

    Directory of Open Access Journals (Sweden)

    Virendra N Sehgal

    2015-01-01

    Full Text Available Tuberous sclerosis complex (TSC is a well-known clinical entity, characterized by facial angio-fibroma, shagreen patch, and hypo-melanotic, and confetti-like skin lesions. An exquisite fresh case is being narrated, emphasizing its microscopic pathology. The role of magnetic resonance imaging of the brain, in particular, is highlighted to define the large variety of neurological abrasions for determining its future progression.

  5. Laser induced plasma plume imaging and surface morphology of silicon

    Energy Technology Data Exchange (ETDEWEB)

    Khaleeq-ur-Rahman, M. [Advanced Physics Laboratory, Department of Physics, University of Engineering and Technology, G.T. Road, Lahore 54890 (Pakistan); Siraj, K. [Advanced Physics Laboratory, Department of Physics, University of Engineering and Technology, G.T. Road, Lahore 54890 (Pakistan)], E-mail: ksiraj@uet.edu.pk; Rafique, M.S.; Bhatti, K.A.; Latif, A.; Jamil, H.; Basit, M. [Advanced Physics Laboratory, Department of Physics, University of Engineering and Technology, G.T. Road, Lahore 54890 (Pakistan)

    2009-04-15

    Shot-to-shot variation in the characteristics of laser produced plasma plume and surface profile of N-type silicon (1 1 1) are investigated. In order to produce plasma, a Q-switched Nd: YAG laser (1064 nm, 10 mJ, 9-14 ns) is tightly focused on silicon target in air at room temperature. Target was exposed in such a way that number of laser shots was increased from point to point in ascending order starting from single shot at first point. Target was moved 2 mm after each exposure. In order to investigate shot-to-shot variation in the time integrated emission intensity regions within the plasma plume, a computer controlled CCD based image capture system was employed. Various intensity regimes were found depending strongly on the number of incident laser pulses. Plasma plume length was also found to vary with the number of pulses. The topographic analysis of the irradiated Si was performed by Scanning Electron Microscope (SEM) which shows the primary mechanisms like thermal or non-thermal ablation depend on the number of shots. Surface morphological changes were also studied in terms of ripple formation, ejection, debris and re-deposition of material caused by laser beam at sample surface. The micrographs show ripples spacing versus wavelength dependence rule [{lambda} {approx} {lambda}/(1 - sin {theta})]. Intensity variations with number of shots are correlated with the surface morphology of the irradiated sample.

  6. Measuring diagnostic accuracy of imaging parameters in pelvic lipomatosis

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yudong, E-mail: pku_zyd06@163.com [Department of Radiology, Peking University First Hospital, Beijing (China); Wu, Shiliang, E-mail: wushiliangjsh@263.net [Department of Urology, Peking University First Hospital, Beijing (China); Xi, Zhijun, E-mail: xizhijun@hsc.pku.edu.cn [Department of Urology, Peking University First Hospital, Beijing (China); Wang, Xiaoying, E-mail: cjr.wangxiaoying@vip.163.com [Department of Radiology, Peking University First Hospital, Beijing (China); Jiang, Xuexiang, E-mail: cjr.jxx@vip.163.com [Department of Radiology, Peking University First Hospital, Beijing (China)

    2012-11-15

    Objectives: To study whether the individual radiological findings can help predict diagnosis of pelvic lipomatosis (PL) or, specifically appreciate its progression. Methods: Data from 32 clinically proven cases of PL and 25 controls were collected. Two reviewers were recruited for a blinded evaluation, image features were recorded in terms of: (1) bladder shape; (2) bladder-rectosigmoid morphological indexes including ratio of superior-inferior to anterior-posterior length of bladder (SI/AP), angle between anterior and posterior wall (AAP), relative length of posterior urethra (rLPU), angle between bladder and seminal vesicle (ABS) and rectosigmoid morphological index (RMI); (3) secondary complications. Results were evaluated by an unpaired t test and ROC analysis. Results: The sensitivity and specificity were 40.6% and 100% for pear and banana-shaped bladder, 62.5% and 100% for SI/AP, 40.6% and 100% for AAP, 62.5% and 100% for ABS, 78.1% and 72% for rLPU, 59.4% and 96% for RMI, respectively. These radiological findings partially correlated with the severity of disease weighted by hydronephrosis and treatment grade. Image analysis demonstrated high prevalence of glandular cystitis (100%) and hydronephrosis (73.4%). Conclusion: We conclude that PL is a progressive disease involving multiple pelvic organs with high prevalence of intractable cystitis and hydronephrosis. The imaging characteristics can help predict diagnosis and, specifically appreciate progression.

  7. Comparison of different phantoms used in digital diagnostic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Bor, Dogan, E-mail: bor@eng.ankara.edu.tr [Ankara University, Faculty of Engineering, Department of Engineering Physics. Tandogan, 06100 Ankara (Turkey); Unal, Elif, E-mail: elf.unall@gmail.com [Radat Dosimetry Laboratory Services, 06830, Golbasi, Ankara (Turkey); Uslu, Anil, E-mail: m.aniluslu@gmail.com [Radat Dosimetry Laboratory Services, 06830, Golbasi, Ankara (Turkey)

    2015-09-21

    The organs of extremity, chest, skull and lumbar were physically simulated using uniform PMMA slabs with different thicknesses alone and using these slabs together with aluminum plates and air gaps (ANSI Phantoms). The variation of entrance surface air kerma and scatter fraction with X-ray beam qualities was investigated for these phantoms and the results were compared with those measured from anthropomorphic phantoms. A flat panel digital radiographic system was used for all the experiments. Considerable variations of entrance surface air kermas were found for the same organs of different designs, and highest doses were measured for the PMMA slabs. A low contrast test tool and a contrast detail test object (CDRAD) were used together with each organ simulation of PMMA slabs and ANSI phantoms in order to test the clinical image qualities. Digital images of these phantom combinations and anthropomorphic phantoms were acquired in raw and clinically processed formats. Variation of image quality with kVp and post processing was evaluated using the numerical metrics of these test tools and measured contrast values from the anthropomorphic phantoms. Our results indicated that design of some phantoms may not be efficient enough to reveal the expected performance of the post processing algorithms.

  8. Comparison of different phantoms used in digital diagnostic imaging

    Science.gov (United States)

    Bor, Dogan; Unal, Elif; Uslu, Anil

    2015-09-01

    The organs of extremity, chest, skull and lumbar were physically simulated using uniform PMMA slabs with different thicknesses alone and using these slabs together with aluminum plates and air gaps (ANSI Phantoms). The variation of entrance surface air kerma and scatter fraction with X-ray beam qualities was investigated for these phantoms and the results were compared with those measured from anthropomorphic phantoms. A flat panel digital radiographic system was used for all the experiments. Considerable variations of entrance surface air kermas were found for the same organs of different designs, and highest doses were measured for the PMMA slabs. A low contrast test tool and a contrast detail test object (CDRAD) were used together with each organ simulation of PMMA slabs and ANSI phantoms in order to test the clinical image qualities. Digital images of these phantom combinations and anthropomorphic phantoms were acquired in raw and clinically processed formats. Variation of image quality with kVp and post processing was evaluated using the numerical metrics of these test tools and measured contrast values from the anthropomorphic phantoms. Our results indicated that design of some phantoms may not be efficient enough to reveal the expected performance of the post processing algorithms.

  9. Study on re-sputtering during CN{sub x} film deposition through spectroscopic diagnostics of plasma

    Energy Technology Data Exchange (ETDEWEB)

    Liang, Peipei; Yang, Xu; Li, Hui; Cai, Hua [Department of Optical Science and Engineering, Fudan University, Shanghai 200433 (China); Sun, Jian; Xu, Ning [Department of Optical Science and Engineering, Fudan University, Shanghai 200433 (China); Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Fudan University, Shanghai 200433 (China); Wu, Jiada, E-mail: jdwu@fudan.edu.cn [Department of Optical Science and Engineering, Fudan University, Shanghai 200433 (China); Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Fudan University, Shanghai 200433 (China); Engineering Research Center of Advanced Lighting Technology, Ministry of Education, Fudan University, Shanghai 200433 (China)

    2015-10-15

    A nitrogen-carbon plasma was generated during the deposition of carbon nitride (CN{sub x}) thin films by pulsed laser ablation of a graphite target in a discharge nitrogen plasma, and the optical emission of the generated nitrogen-carbon plasma was measured for the diagnostics of the plasma and the characterization of the process of CN{sub x} film deposition. The nitrogen-carbon plasma was recognized to contain various species including nitrogen molecules and molecular ions excited in the ambient N{sub 2} gas, carbon atoms and atomic ions ablated from the graphite target and CN radicals. The temporal evolution and spatial distribution of the CN emission and their dependence on the substrate bias voltage show two groups of CN radicals flying in opposite directions. One represents the CN radicals formed as the products of the reactions occurring in the nitrogen-carbon plasma, revealing the reactive deposition of CN{sub x} film due to the reactive expansion of the ablation carbon plasma in the discharge nitrogen plasma and the effective formation of gaseous CN radicals as precursors for CN{sub x} film growth. The other one represents the CN radicals re-sputtered from the growing CN{sub x} film by energetic plasma species, evidencing the re-sputtering of the growing film accompanying film growth. And, the re-sputtering presents ion-induced sputtering features.

  10. Diagnostic image quality of hysterosalpingography: ionic versus non ionic water soluble iodinated contrast media

    Science.gov (United States)

    Mohd Nor, H; Jayapragasam, KJ; Abdullah, BJJ

    2009-01-01

    Objective To compare the diagnostic image quality between three different water soluble iodinated contrast media in hysterosalpingography (HSG). Material and method In a prospective randomised study of 204 patients, the diagnostic quality of images obtained after hysterosalpingography were evaluated using Iopramide (106 patients) and Ioxaglate (98 patients). 114 patients who had undergone HSG examination using Iodamide were analysed retrospectively. Image quality was assessed by three radiologists independently based on an objective set of criteria. The obtained results were statistically analysed using Kruskal-Wallis and Mann-Whitney U test. Results Visualisation of fimbrial rugae was significantly better with Iopramide and Ioxaglate than Iodamide. All contrast media provided acceptable diagnostic image quality with regard to uterine, fallopian tubes outline and peritoneal spill. Uterine opacification was noted to be too dense in all three contrast media and not optimal for the assessment of intrauterine pathology. Higher incidence of contrast intravasation was noted in the Iodamide group. Similarly, the numbers of patients diagnosed with bilateral blocked fallopian tubes were also higher in the Iodamide group. Conclusion HSG using low osmolar contrast media (Iopramide and Ioxaglate) demonstrated diagnostic image qualities similar to HSG using conventional high osmolar contrast media (Iodamide). However, all three contrast media were found to be too dense for the detection of intrauterine pathology. Better visualisation of the fimbrial outline using Ioxaglate and Iopramide were attributed to their low contrast viscosity. The increased incidence of contrast media intravasation and bilateral tubal blockage using Iodamide are probably related to the high viscosity. PMID:21611058

  11. Cost Analysis on Imaging Diagnostic Techniques in Cerebral and Abdominal Neonatal Pathology

    Directory of Open Access Journals (Sweden)

    Carolina BOTAR-JID

    2009-12-01

    Full Text Available Background: Improvement of health care quality and cost control are the main aims of the health care reform in Romania. Objective: The aims of the research are to analyse the trend of costs for imaging techniques used as diagnostic tools for cerebral and abdominal neonatal pathology and to study the relationship between cost and diagnostic benefits. Design: This is a retrospective observational study design without a control group, conducted in the Radio-Imaging Department, Cluj District University Hospital, Romania, from October 2000 to February 2006. Patients: The study population was represented by neonates investigated in the Radio-Imaging Department, Cluj District University Hospital. Intervention: Five imaging diagnostic techniques used in the diagnosis of cerebral and abdominal neonatal pathology were investigated. Measurements: The costs of the investigated techniques were calculated. The concordance between clinical and imaging diagnostic was recorded. Results: Magnetic resonance proved to be the most expensive investigation. The rate between the raising of costs on investigation type on year was constant. The average cost of imaging investigations for patients with identified pathological aspects (€ 42.72 was not statistically significant (p > 0.05 compared with the average cost for patients with no pathologic imaging aspects (€ 37.62. The concordance between the clinical suspicion and the radio-imaging diagnosis was of 52.35%. Conclusions: The raise of radio-imaging investigation costs had a decreasing tendency over the years studied, decrease explained by the stabilization of the Romanian monetary market. The results on concordance analysis lead to the necessity of training of both clinicians and radiologists.

  12. The diagnostic value of the sagittal multiplanar reconstruction CT images for nasal bone fractures

    Energy Technology Data Exchange (ETDEWEB)

    Kim, B.H. [Department of Radiology, Korea University Ansan Hospital, 516 Gojan1-dong, Danwon-gu, Ansan-si, Gyunggi-do, 425-707 (Korea, Republic of); Seo, H.S., E-mail: seohs@korea.ac.k [Department of Radiology, Korea University Ansan Hospital, 516 Gojan1-dong, Danwon-gu, Ansan-si, Gyunggi-do, 425-707 (Korea, Republic of); Kim, A.-Y.; Lee, Y.S. [Department of Radiology, Dongguk University International Hospital, Gyunggi-do (Korea, Republic of); Lee, Y.H. [Department of Radiology, Korea University Ansan Hospital, 516 Gojan1-dong, Danwon-gu, Ansan-si, Gyunggi-do, 425-707 (Korea, Republic of); Suh, S.-I. [Department of Diagnostic Radiology, Korea University Guro Hospital, Seoul (Korea, Republic of); Lee, D.H. [Department of Radiology, Seoul Medical Center, Seoul (Korea, Republic of)

    2010-04-15

    Aim: To compare the diagnostic performance of sagittal multiplanar reconstruction (MPR) images and axial images for the detection of a nasal bone fracture. Materials and methods: This prospective study included 533 consecutive patients who underwent three-dimensional images with 64-section multidetector-row CT for the evaluation of a facial bone fracture between June 2007 and May 2008 (366 males; 167 females; mean age +- standard deviation 31.1 +- 21.2 years; age range 1-92 years). Two observers independently scored the possibility of a nasal bone fracture on axial and sagittal images. Receiver operating characteristic (ROC) curve analysis was performed. Results: The Az values of the sagittal images were higher than those of the axial images for both observers (p = 0.002 and 0.010, respectively) with higher accuracy (p < 0.001 and 0.016, respectively). The sensitivities of sagittal images were superior to those of axial images, especially for type 1 simple nasal bone fractures with no or minimal displacement (observer 1, 98.6 versus 72.8%; observer 2, 84.9 versus 71%). Conclusion: Sagittal MPR facial bone CT images provided superior diagnostic performance, and their addition to axial images is useful for the evaluation of nasal bone fractures.

  13. Development of horn antenna mixer array with internal local oscillator module for microwave imaging diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Kuwahara, D., E-mail: dkuwahar@cc.tuat.ac.jp [Department of Mechanical Systems Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588 (Japan); Ito, N. [Department of Intelligent System Engineering, Ube National College of Technology, Ube, Yamaguchi 755-8555 (Japan); Nagayama, Y. [Department of Helical Plasma Research, National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Yoshinaga, T. [Department of Applied Physics, National Defense Academy, Yokosuka, Kanagawa 239-0811 (Japan); Yamaguchi, S. [Department of Pure and Applied Physics, Kansai University, Suita, Osaka 564-8680 (Japan); Yoshikawa, M.; Kohagura, J. [Graduate School of Pure and Applied Science, University of Tsukuba, Tsukuba, Ibaraki 305-8577 (Japan); Sugito, S. [Equipment Development Center, Institute for Molecular Science, Okazaki, Aichi 444-8585 (Japan); Kogi, Y. [Department of Information Electronics, Fukuoka Institute of Technology, Fukuoka, Fukuoka 811-0295 (Japan); Mase, A. [Art, Science and Technology Center for Cooperative Research, Kyusyu University, Kasuga, Fukuoka 816-8580 (Japan)

    2014-11-15

    A new antenna array is proposed in order to improve the sensitivity and complexity of microwave imaging diagnostics systems such as a microwave imaging reflectometry, a microwave imaging interferometer, and an electron cyclotron emission imaging. The antenna array consists of five elements: a horn antenna, a waveguide-to-microstrip line transition, a mixer, a local oscillation (LO) module, and an intermediate frequency amplifier. By using an LO module, the LO optics can be removed, and the supplied LO power to each element can be equalized. We report details of the antenna array and characteristics of a prototype antenna array.

  14. Phase-contrast enhanced mammography: A new diagnostic tool for breast imaging

    Energy Technology Data Exchange (ETDEWEB)

    Wang Zhentian; Thuering, Thomas; David, Christian; Roessl, Ewald; Trippel, Mafalda; Kubik-Huch, Rahel A.; Singer, Gad; Hohl, Michael K.; Hauser, Nik; Stampanoni, Marco [Swiss Light Source, Paul Scherrer Institut, 5232 Villigen (Switzerland); Laboratory for Micro and Nanotechnology, Paul Scherrer Institut, 5232 Villigen (Switzerland); Philips Technologie GmbH, Roentgenstrasse 24, 22335 Hamburg (Germany); Institute of Pathology, Kantonsspital Baden, 5404 Baden (Switzerland); Department of Radiology, Kantonsspital Baden, 5404 Baden (Switzerland); Institute of Pathology, Kantonsspital Baden, 5404 Baden (Switzerland); Department of Gynecology and Obstetrics, Interdisciplinary Breast Center Baden, Kantonsspital Baden, 5404 Baden (Switzerland); Swiss Light Source, Paul Scherrer Institut, 5232 Villigen, Switzerland and Institute for Biomedical Engineering, University and ETH Zuerich, 8092 Zuerich (Switzerland)

    2012-07-31

    Phase contrast and scattering-based X-ray imaging can potentially revolutionize the radiological approach to breast imaging by providing additional and complementary information to conventional, absorption-based methods. We investigated native, non-fixed whole breast samples using a grating interferometer with an X-ray tube-based configuration. Our approach simultaneously recorded absorption, differential phase contrast and small-angle scattering signals. The results show that this novel technique - combined with a dedicated image fusion algorithm - has the potential to deliver enhanced breast imaging with complementary information for an improved diagnostic process.

  15. Magnetic resonance imaging of the shoulder: a review of potential sources of diagnostic errors

    Energy Technology Data Exchange (ETDEWEB)

    Carroll, K.W. [Radiology Regional Center, Naples, FL (United States); Helms, C.A. [Duke University Medical Center, Department of Radiology, Durham, NC (United States)

    2002-07-01

    Shoulder magnetic resonance (MR) imaging and MR arthrography are frequently utilized in the evaluation of shoulder pain and instability. The clinical scenario and imaging findings may be confusing to clinicians and radiologists and may present diagnostic challenges for those involved in evaluating and treating shoulder pathology. Often rotator cuff and labral abnormalities may be coexistent, clinical manifestations of denervation syndromes may be confusing to clinicians, and normal anatomic variations, imaging pitfalls, and various artifacts may cause dilemmas for the radiologist. This article will review the most frequently encountered mimickers and pitfalls of MR imaging of the shoulder. (orig.)

  16. Development of horn antenna mixer array with internal local oscillator module for microwave imaging diagnostics.

    Science.gov (United States)

    Kuwahara, D; Ito, N; Nagayama, Y; Yoshinaga, T; Yamaguchi, S; Yoshikawa, M; Kohagura, J; Sugito, S; Kogi, Y; Mase, A

    2014-11-01

    A new antenna array is proposed in order to improve the sensitivity and complexity of microwave imaging diagnostics systems such as a microwave imaging reflectometry, a microwave imaging interferometer, and an electron cyclotron emission imaging. The antenna array consists of five elements: a horn antenna, a waveguide-to-microstrip line transition, a mixer, a local oscillation (LO) module, and an intermediate frequency amplifier. By using an LO module, the LO optics can be removed, and the supplied LO power to each element can be equalized. We report details of the antenna array and characteristics of a prototype antenna array.

  17. Efficient medical image access in diagnostic environments with limited resources

    Directory of Open Access Journals (Sweden)

    José Eduardo Venson

    Full Text Available Abstract Introduction A medical application running outside the workstation environment has to deal with several constraints, such as reduced available memory and low network bandwidth. The aim of this paper is to present an approach to optimize the data flow for fast image transfer and visualization on mobile devices and remote stationary devices. Methods We use a combination of client- and server-side procedures to reduce the amount of information transferred by the application. Our approach was implemented on top of a commercial PACS and evaluated through user experiments with specialists in typical diagnosis tasks. The quality of the system outcome was measured in relation to the accumulated amount of network data transference and the amount of memory used in the host device. Besides, the system's quality of use (usability was measured through participants’ feedback. Results Contrarily to previous approaches, ours keeps the application within the memory constraints, minimizing data transferring whenever possible, allowing the application to run on a variety of devices. Moreover, it does that without sacrificing the user experience. Experimental data point that over 90% of the users did not notice any delays or degraded image quality, and when they did, they did not impact on the clinical decisions. Conclusion The combined activities and orchestration of our methods allow the image viewer to run on resource-constrained environments, such as those with low network bandwidth or little available memory. These results demonstrate the ability to explore the use of mobile devices as a support tool in the medical workflow.

  18. Cortical vein thrombosis: the diagnostic value of different imaging modalities

    Energy Technology Data Exchange (ETDEWEB)

    Linn, Jennifer; Michl, Stefan; Katja, Bochmann; Hartz, Sabine; Brueckmann, Hartmut [University Hospital Munich, Department of Neuroradiology, Munich (Germany); Pfefferkorn, Thomas; Dichgans, Martin [University Hospital Munich, Department of Neurology, Munich (Germany); Wiesmann, Martin [University Hospital Munich, Department of Neuroradiology, Munich (Germany); Helios Kliniken Schwerin, Department of Radiology and Neuroradiology, Schwerin (Germany)

    2010-10-15

    Cortical vein thrombosis (CVT) is a rare disorder, and its diagnosis is challenging. The aim of our study was to evaluate the value of different imaging modalities for the detection of CVT. Thirteen patients with CVT, either isolated (n = 3) or in combination with sinus thrombosis (n = 10), and 20 control patients without any venous pathologies were included in this study. The analysis was performed independently by three blinded readers who evaluated the following imaging modalities and sequences separately: non-enhanced computed tomography (NCCT); multi-detector row CT angiography (MDCTA); diffusion-weighted (DWI), T1-weighted (T1w), PD-weighted (PDw), T2*-weighted (T2*w), and fluid-attenuated inversion recovery-weighted (FLAIRw) magnetic resonance (MR) sequences; as well as venous MR angiography (vMRA). The sensitivity, specificity, positive (PPV) and negative predictive values, and interobserver agreement of the different modalities were calculated. T2*w showed the highest sensitivity for the detection of CVT (97.4%), followed by T1w (70%). FLAIRw and vMRA had a sensitivity of 50% and 41.7%, respectively, whereas the sensitivity of NCCT, MDCTA, DWI, and PDw was below 30%. The specificity and PPV of all modalities was 100%, with good to perfect interobserver agreement. T2*w was the superior MR imaging sequence for diagnosing CVT. Besides T2*w, only T1w reached a sensitivity of over 50% for CVT, followed by FLAIRw, and vMRA. On the contrary, our results suggest that NCCT but also MDCTA might not be suitable for diagnosing CVT. (orig.)

  19. A complex communicating bronchopulmonary foregut malformation: diagnostic imaging and pathogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Sumner, T.E.; Auringer, S.T.; Cox, T.D. [Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Medical Center Boulevard, Winston-Salem, NC 27157-1088 (United States)

    1997-10-01

    We report a newborn with an esophageal lung, a rare type of communicating bronchopulmonary foregut malformation (CBPFM). Associated findings included esophageal atresia, tracheoesophageal fistula (TEF) to the distal esophagus, duodenal stenosis with annular pancreas, imperforate anus, vertebral anomalies and ambiguous genitalia. Radiologic evaluation included chest radiographs, esophagrams, chest ultrasound and chest CT. After colostomy and surgical repair of duodenal stenosis and TEF, a right thoracotomy was performed to treat an esophageal lung. Radiologic features of this unusual variant of CBPFM are presented. Accurate preoperative imaging diagnosis is essential for planning surgical treatment of an esophageal lung. (orig.). With 1 fig.

  20. Diagnostic imaging in a patient with an acute knee injury.

    Science.gov (United States)

    Sago, Carrie E; Labuda, Craig S

    2013-01-01

    The patient was a 23-year-old man, currently serving in a military airborne operations unit. During a jump training exercise, the patient's right lower extremity became entangled in his parachute equipment upon exiting the aircraft, which caused hyperextension and valgus forces upon his right knee. Due to concern for a fracture, the patient was transported to an emergency department, where conventional radiographs were completed and interpreted by a radiologist as negative for a fracture. Following further physical examination by a physical therapist, magnetic resonance imaging of the right knee was ordered, revealing ruptures of the anterior cruciate ligament and medial collateral ligament.

  1. Diagnostic imaging in COPD; Radiologische Diagnostik bei COPD

    Energy Technology Data Exchange (ETDEWEB)

    Owsijewitsch, Michael; Ley-Zaporozhan, Julia [Universitaetsklinik Heidelberg (Germany). Klinik fuer Diagnostische und Interventionelle Radiologie; Eichinger, Monika [Deutsches Krebsforschungszentrum (DKFZ), Heidelberg (Germany). Abt. Radiologie

    2011-03-15

    COPD is a heterogeneous disease defined by expiratory airflow limitation. Airflow limitation is caused by a variable combination of emphysematous destruction of lung parenchyma and small airway obstruction. Only advanced emphysema can be diagnosed by chest X-ray. Less severe emphysema and changes in small airways are commonly diagnosed by computed tomography. Typical visual appearance of pathologic changes in lung parenchyma and airways of COPD patients are presented, furthermore methods for quantitative assessment of these changes and the crucial role of imaging for surgical and bronchoscopic treatment in COPD are discussed. (orig.)

  2. Feasibility of arc-discharge and plasma-sputtering methods in cleaning plasma-facing and diagnostics components of fusion reactors

    Energy Technology Data Exchange (ETDEWEB)

    Hakola, Antti, E-mail: antti.hakola@vtt.fi [VTT Technical Research Centre of Finland, VTT (Finland); Likonen, Jari [VTT Technical Research Centre of Finland, VTT (Finland); Karhunen, Juuso; Korhonen, Juuso T. [Department of Applied Physics, Aalto University (Finland); Aints, Märt; Laan, Matti; Paris, Peeter [Department of Physics, University of Tartu (Estonia); Kolehmainen, Jukka; Koskinen, Mika; Tervakangas, Sanna [DIARC-Technology Oy, Espoo (Finland)

    2015-10-15

    Highlights: • Feasibility of the arc-discharge and plasma-sputtering techniques in removing deposited layers from ITER-relevant samples demonstrated. • Samples with the size of an A4 paper can be cleaned from 1-μm thick deposited layers in 10–20 minutes by the arc-discharge method. • The plasma-sputtering method is 5–10 times slower but the resulting surfaces are very smooth. • Arc-discharge method could be used for rapid cleaning of plasma-facing components during maintenance shutdowns of ITER, plasma sputtering is preferred for diagnostics mirrors. - Abstract: We have studied the feasibility of arc-discharge and plasma-sputtering methods in removing deposited layers from ITER-relevant test samples. Prototype devices have been designed and constructed for the experiments and the cleaning process is monitored by a spectral detection system. The present version of the arc-discharge device is capable of removing 1-μm thick layers from 350-mm{sup 2} areas in 4–8 s, but due to the increased roughness of the cleaned surfaces and signs of local melting, mirror-like surfaces cannot be treated by this technique. The plasma-sputtering approach, for its part, is some 5–10 times slower in removing the deposited layers but no changes in surface roughness or morphology of the samples could be observed after the cleaning phase. The arc-discharge technique could therefore be used for rapid cleaning of plasma-facing components during maintenance shutdowns of ITER while in the case of diagnostics mirrors plasma sputtering is preferred.

  3. Use of radiolabeled monoclonal antibodies for diagnostic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Endo, Keigo (Kyoto Univ. (Japan). Faculty of Medicine)

    1990-08-01

    Monoclonal antibodies (MoAbs) are expected to carry radionuclides selectively to target tissues and to offer antigen-specific diagnosis. Indium (In)-111 has many favorable nuclear properties and is efficiently labeled with MoAbs using DAPA as a bifunctional chelating agent. In-111 labeled MoAbs are clinically employed for the diagnosis of malignant melanoma, colorectal cancer and acute myocardial infarction in Japan. Although non-specific deposit of In-111 was seen in liver and bone-marrow, scintigraphy using In-111 labeled MoAbs was encouraging, since it detected about 80% of tumors, tumors missed by conventional diagnostic methods such as CT, and tumors in patients with normal serum CEA values, and acute myocarditis as well as acute myocardial infarction was positive with In-111 labeled Fab fraction of anti-myosin Ab. Acute or subacute toxicity was not observed. Human anti-murine antibody (HAMA) was detected in 53 of 64 (82.8%) patients who were intravenously administered with 20 to 42 mg of anti-melanoma or anti-CEA MoAbs (whole IgG). In contrast, only 5 of 406 (1.2%) patients had detectable levels of HAMA in their serum after receiving 0.5 mg of Fab fraction of MoAb. Recently mouse-human chimeric Ab has been produced by recombinant DNA techniques, which localized well in xenografted tumors and seems to be promising for clinical use. Investigations are under way to increase the tumor to non-tumor ratio by modifying chelating agents for coupling MoAbs with radionuclides. (author).

  4. [Wernicke-Korsakoff syndrome: diagnostic contribution of magnetic resonance imaging].

    Science.gov (United States)

    Varnet, O; de Seze, J; Soto-Ares, G; Tiberghien, F; Caparros-Lefebvre, D; Daems, C; Pasquier, F; Pruvo, J P; Destée, A; Vermesch, P

    2002-12-01

    Data regarding the magnetic resonance imaging (MRI) features in Wernicke-Korsakoff syndrome (WKS) are scarce. WKS usually combines a cerebellar syndrome, oculomotor disorder and confusion. The aim of this study was to determine more precisely the clinical presentation of WKS and the frequency and topography of MRI abnormalities. Furthermore, we try to assess the prognostic value of both clinical signs and MRI abnormalities. We retrospectively studied 25 patients with WKS in which an MRI was available. We assessed the initial clinical presentation and the outcome. We also analyzed the frequency and the location of MRI lesions. We then correlated clinical and MRI data with the clinical outcome. Eleven patients (44 p. 100) had the full WKS. Fourteen of the 25 patients (56 p. 100) had a poor evolution. The occurrence of full WKS was correlated with a poor outcome (p < 0.02). Signal abnormalities on T2-weighted images were found in the periacqueducal region, in the thalami or in the mamillar bodies in 16 cases (64 p. 100). There was a correlation between an hypersignal in at least one region and a poor clinical outcome (p < 0.02). Our study demonstrates the high frequency of brain MRI lesions in WKS and the correlation of both initial clinical signs and MRI abnormalities with a poor clinical outcome.

  5. Correlation of diagnostic ultrasound and radionuclide imaging in scrotal disease

    Energy Technology Data Exchange (ETDEWEB)

    Chen, D.C.P.; Holder, L.E.; Kaplan, G.N.

    1984-01-01

    A retrospective study was performed to evaluate the usefulness of scrotal ultrasound imaging (SU) and radionuclide scrotal imaging (RSI) in 43 patients (pts), age: 16-75. Twenty-two of them complained of scrotal pain; 18 had a scrotal mass; and 4 had a history of trauma. The final diagnoses were conformed by surgery (n = 21) and long-term follow-up (n = 22) and included 4 late phase and 1 early testicular torsion (TT), 11 acute epididymitis (AE), 4 subacute epididymitis (SE), 5 malignant tumors, 3 testicular atrophy, 2 intratesticular hematomas, 10 hydroceles or other cystic lesions, and miscellaneous. In pts with scrotal pain, 3/4 with late phase TT were correctly diagnosed, while one pt with early TT and 11/15 with AE or SE were not diagnosed by SU. All of them were correctly diagnosed with RSI except one with scrotal cyst. SU was able to separate cystic masses (n = 10) from solid masses (n = 6), but cannot separate malignant from benign lesions. SU was excellent in detecting 19 hydroceles and 2 intratesticular hematomas, while 3 lesions < 1 cm. were not seen in RSI. The authors concluded that SU is useful in pts with scrotal mass to separate solid from cystic lesions. However, SU is unable to differentiate the acute epididymitis from early testicular torsion. In pts with acute scrotal pain, SU is not helpful and RSI should still be the first study performed.

  6. Application of Six Sigma methodology to a diagnostic imaging process.

    Science.gov (United States)

    Taner, Mehmet Tolga; Sezen, Bulent; Atwat, Kamal M

    2012-01-01

    This paper aims to apply the Six Sigma methodology to improve workflow by eliminating the causes of failure in the medical imaging department of a private Turkish hospital. Implementation of the design, measure, analyse, improve and control (DMAIC) improvement cycle, workflow chart, fishbone diagrams and Pareto charts were employed, together with rigorous data collection in the department. The identification of root causes of repeat sessions and delays was followed by failure, mode and effect analysis, hazard analysis and decision tree analysis. The most frequent causes of failure were malfunction of the RIS/PACS system and improper positioning of patients. Subsequent to extensive training of professionals, the sigma level was increased from 3.5 to 4.2. The data were collected over only four months. Six Sigma's data measurement and process improvement methodology is the impetus for health care organisations to rethink their workflow and reduce malpractice. It involves measuring, recording and reporting data on a regular basis. This enables the administration to monitor workflow continuously. The improvements in the workflow under study, made by determining the failures and potential risks associated with radiologic care, will have a positive impact on society in terms of patient safety. Having eliminated repeat examinations, the risk of being exposed to more radiation was also minimised. This paper supports the need to apply Six Sigma and present an evaluation of the process in an imaging department.

  7. Spectro-Polarimetric Observations of Interplanetary Hydrogen as a Diagnostic of the Heliopause Plasma Boundary

    Science.gov (United States)

    Harris, W.; Ben-Jaffel, L.; Roesler, F.; Corliss, J.; Dawson, O.; Giersch, L.

    2006-12-01

    Neutral interplanetary hydrogen (IPH) does not originate in the solar system, but is dominated by material in the interstellar medium (ISM) that has penetrated into the solar system. This material is not pristine or thermal in its properties, but contains a record of both the ISM and its passage across the broad mixing- plasma boundary formed by the interaction of the Solar wind and the ionized component of the ISM. This record is provided by charge exchange interactions between hydrogen atoms and protons in the boundary region that effectively translate the characteristics of the plasma interaction and boundary region to the non- interacting neutral population. The primary observational technique used to observe IPH is resonance scattering of solar Ly-alpha emission in the optically thick medium. These data show evidence of line of sight dependent line-broadening and deceleration associated with the boundary crossing. Here we describe a new class of instrument, a spatial-heterodyne spectro-polarimeter (SHSPOL) that offers improved diagnostic capabilities for the study of the IPH. SHSPOL combines the high sensitivity and spectral resolving power of SHS with a novel far ultraviolet polarimeter design. Combined, these technologies permit rapid accumulation of IPH line-shape measurements with the added measurement of the offers a new way to explore the radial properties of the IPH along a given line of sight from the scattering angle dependent polarization of the incoming light. We will discuss the principle of SHSPOL and our development of prototype instrument for observing the IPH from a sounding rocket platform.

  8. Plasma diagnostic approach for the low-temperature deposition of silicon quantum dots using dual frequency PECVD

    Science.gov (United States)

    Sahu, B. B.; Yin, Y.; Lee, J. S.; Han, Jeon G.; Shiratani, M.

    2016-10-01

    Although studies of silicon (Si) quantum dots (QDs) were started just a few years ago, progress is noteworthy concerning unique film properties and their potential application for devices. In particular, relating to the Si QD process optimization, it is essential to control the deposition environment by studying the role of plasma parameters and atomic and molecular species in the process plasmas. In this work, we report on advanced material processes for the low-temperature deposition of Si QDs by utilizing radio frequency and ultrahigh frequency dual frequency (DF) plasma enhanced chemical vapor deposition (PECVD) method. DF PECVD can generate a very high plasma density in the range ~9  ×  1010 cm-3 to 3.2  ×  1011 cm-3 at a very low electron temperature (T e) ~ 1.5 to 2.4 eV. The PECVD processes, using a reactive mixture of H2/SiH4/NH3 gases, are carefully studied to investigate the operating regime and to optimize the deposition parameters by utilizing different plasma diagnostic tools. The analysis reveals that a higher ion flux at a higher plasma density on the substrate is conducive to enhancing the overall crystallinity of the deposited film. Along with high-density plasmas, a high concentration of atomic H and N is simultaneously essential for the high growth rate deposition of Si QDs. Numerous plasma diagnostics methods and film analysis tools are used to correlate the effect of plasma- and atomic-radical parameters on the structural and chemical properties of the deposited Si QD films prepared in the reactive mixtures of H2/SiH4/NH3 at various pressures.

  9. Using complex networks towards information retrieval and diagnostics in multidimensional imaging

    CERN Document Server

    Banerjee, Soumya Jyoti; Sen, Debanjan; Savale, Smruti; Datta, Himadri; Dasgupta, Anjan Kr; Roy, Soumen

    2015-01-01

    We present a fresh and general yet simple approach towards information retrieval in general and diagnostics in particular by applying the theory of complex networks on multidimensional images. We demonstrate a successful use of our method with the time series generated from high content thermal imaging videos of patients suffering from aqueous deficient dry eye (ADDE) disease. The approach is scalable to a device where fluctuation derived network parameters serve as diagnostic markers. Remarkably, network analysis of thermal imaging time series of contact lens users and patients upon whom Laser-Assisted in situ Keratomileusis (Lasik) surgery has been conducted, exhibits pronounced similarities with results obtained from ADDE patients. We also propose a general framework for transformation of multidimensional images to networks for futuristic biometry.

  10. [Role of cone-beam computed tomography in diagnostic otorhinolaryngological imaging].

    Science.gov (United States)

    Perényi, Ádám; Bella, Zsolt; Baráth, Zoltán; Magyar, Péter; Nagy, Katalin; Rovó, László

    2016-01-10

    Accurate diagnosis and preoperative planning in modern otorhinolaryngology is strongly supported by imaging with enhanced visualization. Computed tomography is often used to examine structures within bone frameworks. Given the hazards of ionizing radiation, repetitive imaging studies exponentially increase the risk of damages to radiosensitive tissues. The authors compare multislice and cone-beam computed tomography and determine the role, advantages and disadvantages of cone-beam computed tomography in otorhinolaryngological imaging. They summarize the knowledge from the international literature and their individual imaging studies. They conclude that cone-beam computed tomography enables high-resolution imaging and reconstruction in any optional plane and in space with considerably lower effective radiation dose. Cone-beam computed tomography with appropriate indications proved to be an excellent diagnostic tool in otorhinolaryngological imaging. It makes an alternative to multislice computed tomography and it is an effective tool in perioperative and postoperative follow-up, especially in those cases which necessitate repetitive imaging with computed tomography.

  11. Predicting diagnostic error in radiology via eye-tracking and image analytics: Preliminary investigation in mammography

    Energy Technology Data Exchange (ETDEWEB)

    Voisin, Sophie; Tourassi, Georgia D. [Biomedical Science and Engineering Center, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 (United States); Pinto, Frank [School of Engineering, Science, and Technology, Virginia State University, Petersburg, Virginia 23806 (United States); Morin-Ducote, Garnetta; Hudson, Kathleen B. [Department of Radiology, University of Tennessee Medical Center at Knoxville, Knoxville, Tennessee 37920 (United States)

    2013-10-15

    Purpose: The primary aim of the present study was to test the feasibility of predicting diagnostic errors in mammography by merging radiologists’ gaze behavior and image characteristics. A secondary aim was to investigate group-based and personalized predictive models for radiologists of variable experience levels.Methods: The study was performed for the clinical task of assessing the likelihood of malignancy of mammographic masses. Eye-tracking data and diagnostic decisions for 40 cases were acquired from four Radiology residents and two breast imaging experts as part of an IRB-approved pilot study. Gaze behavior features were extracted from the eye-tracking data. Computer-generated and BIRADS images features were extracted from the images. Finally, machine learning algorithms were used to merge gaze and image features for predicting human error. Feature selection was thoroughly explored to determine the relative contribution of the various features. Group-based and personalized user modeling was also investigated.Results: Machine learning can be used to predict diagnostic error by merging gaze behavior characteristics from the radiologist and textural characteristics from the image under review. Leveraging data collected from multiple readers produced a reasonable group model [area under the ROC curve (AUC) = 0.792 ± 0.030]. Personalized user modeling was far more accurate for the more experienced readers (AUC = 0.837 ± 0.029) than for the less experienced ones (AUC = 0.667 ± 0.099). The best performing group-based and personalized predictive models involved combinations of both gaze and image features.Conclusions: Diagnostic errors in mammography can be predicted to a good extent by leveraging the radiologists’ gaze behavior and image content.

  12. Predicting diagnostic error in Radiology via eye-tracking and image analytics: Application in mammography

    Energy Technology Data Exchange (ETDEWEB)

    Voisin, Sophie [ORNL; Pinto, Frank M [ORNL; Morin-Ducote, Garnetta [University of Tennessee, Knoxville (UTK); Hudson, Kathy [University of Tennessee, Knoxville (UTK); Tourassi, Georgia [ORNL

    2013-01-01

    Purpose: The primary aim of the present study was to test the feasibility of predicting diagnostic errors in mammography by merging radiologists gaze behavior and image characteristics. A secondary aim was to investigate group-based and personalized predictive models for radiologists of variable experience levels. Methods: The study was performed for the clinical task of assessing the likelihood of malignancy of mammographic masses. Eye-tracking data and diagnostic decisions for 40 cases were acquired from 4 Radiology residents and 2 breast imaging experts as part of an IRB-approved pilot study. Gaze behavior features were extracted from the eye-tracking data. Computer-generated and BIRADs images features were extracted from the images. Finally, machine learning algorithms were used to merge gaze and image features for predicting human error. Feature selection was thoroughly explored to determine the relative contribution of the various features. Group-based and personalized user modeling was also investigated. Results: Diagnostic error can be predicted reliably by merging gaze behavior characteristics from the radiologist and textural characteristics from the image under review. Leveraging data collected from multiple readers produced a reasonable group model (AUC=0.79). Personalized user modeling was far more accurate for the more experienced readers (average AUC of 0.837 0.029) than for the less experienced ones (average AUC of 0.667 0.099). The best performing group-based and personalized predictive models involved combinations of both gaze and image features. Conclusions: Diagnostic errors in mammography can be predicted reliably by leveraging the radiologists gaze behavior and image content.

  13. Gold-manganese nanoparticles for targeted diagnostic and imaging

    Energy Technology Data Exchange (ETDEWEB)

    Murph, Simona Hunyadi [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-11-10

    Imagine the possibility of non-invasive, non-radiation based Magnetic resonance imaging (MRI) in combating cardiac disease. Researchers at the Savannah River National Laboratory (SRNL) are developing a process that would use nanotechnology in a novel, targeted approach that would allow MRIs to be more descriptive and brighter, and to target specific organs. Researchers at SRNL have discovered a way to use multifunctional metallic gold-manganese nanoparticles to create a unique, targeted positive contrast agent. SRNL Senior Scientist Dr. Simona Hunyadi Murph says she first thought of using the nanoparticles for cardiac disease applications after learning that people who survive an infarct exhibit up to 15 times higher rate of developing chronic heart failure, arrhythmias and/or sudden death compared to the general population. Without question, nanotechnology will revolutionize the future of technology. The development of functional nanomaterials with multi-detection modalities opens up new avenues for creating multi-purpose technologies for biomedical applications.

  14. Radiation exposure from diagnostic imaging in young patients with testicular cancer

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, C.J.; Twomey, M.; O' Regan, K.N. [Cork and Mercy University Hospitals, Department of Radiology, Cork (Ireland); Murphy, K.P.; Maher, M.M.; O' Connor, O.J. [Cork and Mercy University Hospitals, Department of Radiology, Cork (Ireland); University College Cork, Department of Radiology, Cork (Ireland); McLaughlin, P.D. [Cork and Mercy University Hospitals, Department of Radiology, Cork (Ireland); Vancouver General Hospital, Department of Emergency and Trauma Radiology, Vancouver, British Columbia (Canada); Power, D.G. [Cork and Mercy University Hospitals, Department of Medical Oncology, Cork (Ireland)

    2015-04-01

    Risks associated with high cumulative effective dose (CED) from radiation are greater when imaging is performed on younger patients. Testicular cancer affects young patients and has a good prognosis. Regular imaging is standard for follow-up. This study quantifies CED from diagnostic imaging in these patients. Radiological imaging of patients aged 18-39 years, diagnosed with testicular cancer between 2001 and 2011 in two tertiary care centres was examined. Age at diagnosis, cancer type, dose-length product (DLP), imaging type, and frequency were recorded. CED was calculated from DLP using conversion factors. Statistical analysis was performed with SPSS. In total, 120 patients with a mean age of 30.7 ± 5.2 years at diagnosis had 1,410 radiological investigations. Median (IQR) surveillance was 4.37 years (2.0-5.5). Median (IQR) CED was 125.1 mSv (81.3-177.5). Computed tomography accounted for 65.3 % of imaging studies and 98.3 % of CED. We found that 77.5 % (93/120) of patients received high CED (>75 mSv). Surveillance time was associated with high CED (OR 2.1, CI 1.5-2.8). Survivors of testicular cancer frequently receive high CED from diagnostic imaging, mainly CT. Dose management software for accurate real-time monitoring of CED and low-dose CT protocols with maintained image quality should be used by specialist centres for surveillance imaging. (orig.)

  15. Diagnostic imaging in neonatal stroke; Bildgebende Diagnostik des Neonatal stroke

    Energy Technology Data Exchange (ETDEWEB)

    Kuhle, S.; Ipsiroglu, O.; Weninger, M. [Universitaetsklinik fuer Kinder- und Jugendheilkunde, Wien (Austria). Abt. fuer Neonatologie, angeborene Stoerungen und Intensivmedizin; Puig, S.; Prayer, D. [Universitaetsklinik fuer Radiodiagnostik, Wien (Austria)

    2000-01-01

    A cerebral artery infarction is an important differential diagnosis in the newborn with neurological abnormalities. Based on clinical data, its incidence is estimated to be 1 in 4000 newborns. Since the course is often subclinical, the true incidence is probably higher. Diagnosis: Cerebral ultrasound and Doppler sonography as readily available screening tools play a central role in the initial diagnosis of neonatal cerebral infarction. Definitive diagnosis is made by computed tomography or magnetic resonance imaging. Beside symptomatic anticonvulsive therapy, treatment aims at the prevention of secondary ischemic injury. Discussion: Three term infants with different clinical courses of neonatal stroke are presented to sensitize the clinician and the radiologist for this probably underdiagnosed entity. The role of imaging modalities in the diagnosis and follow-up of neonatal cerebral infarction is discussed. (orig.) [German] Ein Infarkt im Stromgebiet der Zerebralarterien stellt eine wichtige Differentialdiagnose bei neurologischen Auffaelligkeiten in der Neonatalperiode dar. Die Inzidenz wird anhand von klinischer Daten auf 1:4000 Lebendgeborene geschaetzt. Da der Verlauf oft subklinisch ist, liegt die wahre Inzidenz wahrscheinlich hoeher. Diagnose: Bei der Diagnosestellung kommen dem Schaedelultraschall und der Doppelsonographie als leicht verfuegbaren Screening-Methoden eine zentrale Rolle zu. Die definitive Diagnose wird, je nach Verfuegbarkeit, mittels Computertomographie oder Kernspintomographie gestellt. Die Behandlung ist neben der symptomatischen (antikonvulsiven) Therapie auf die Vermeidung von ischaemischen Sekundaerschaeden gerichtet. Diskussion: Wir wollen mit der vorliegenden Arbeit anhand von 3 Kindern mit verschiedenen klinischen Verlaeufen eines sog. Neonatal stroke den Stellenwert der bildgebenden Verfahren bei der Diagnostik und Verlaufskontrolle aufzeigen und die Sensibilitaet fuer dieses vermutlich unterdiagnostizierte Krankheitsbild erhoehen

  16. Reliability of whole slide images as a diagnostic modality for renal allograft biopsies.

    Science.gov (United States)

    Jen, Kuang-Yu; Olson, Jean L; Brodsky, Sergey; Zhou, Xin J; Nadasdy, Tibor; Laszik, Zoltan G

    2013-05-01

    The use of digital whole slide images (WSI) in the field of pathology has become feasible for routine diagnostic purposes and has become more prevalent in recent years. This type of technology offers many advantages but must show the same degree of diagnostic reliability as conventional glass slides. Several studies have examined this issue in various settings and indicate that WSI are a reliable method for diagnostic pathology. Since transplant pathology is a highly specialized field that requires not only accurate but rapid diagnostic evaluation of biopsy materials, this field may greatly benefit from the use of WSI. In this study, we assessed the reliability of using WSI compared to conventional glass slides in renal allograft biopsies. We examined morphologic features and diagnostic categories defined by the Banff 07 Classification of Renal Allograft Pathology as well as additional morphologic features not included in this classification scheme. We found that intraobserver scores, when comparing the use of glass slides versus WSI, showed substantial agreement for both morphologic features (κ = 0.68) and acute rejection diagnostic categories (κ = 0.74). Furthermore, interobserver reliability was comparable for morphologic features (κ = 0.44 [glass] vs 0.42 [WSI]) and acute rejection diagnostic categories (κ = 0.49 [glass] vs 0.51 [WSI]). These data indicate that WSI are as reliable as glass slides for the evaluation of renal allograft biopsies.

  17. Advantages of digital imaging for radiological diagnostic; Ventajas de la imagen digital para el diagnostico radiologico

    Energy Technology Data Exchange (ETDEWEB)

    Trapero, M. A.; Gonzalez, S.; Albillos, J. C.; Martel, J.; Rebollo, M.

    2006-07-01

    The advantages and limitations of radiological digital images in comparison with analogic ones are analyzed. We discuss three main topics: acquisition, post-procedure manipulation, and visualization, archive and communication. Digital acquisition with computed radiology systems present a global sensitivity very close to conventional film for diagnostic purposes. However, flat panel digital systems seems to achieve some advantages in particular clinical situations. A critical issue is the radiation dose-reduction that can be accomplished without reducing image quality nor diagnostic exactitude. The post-procedure manipulation allows, particularly in multiplanar modalities like CT or MR, to extract all implicit diagnostic information in the images: Main procedures are multiplanar and three-dimensional reformations, dynamic acquisitions, functional studies and image fusion. The use of PACS for visualization, archive and communication of images, improves the effectiveness and the efficiency of the workflow, allows a more comfortable diagnosis for the radiologist and gives way to improvements in the communication of images, allowing tele consulting and the tele radiology. (Author) 6 refs.

  18. Training for thorax diagnostics. Systematic cardiopulmonary image analysis; Trainer Thoraxdiagnostik. Systematische kardiopulmonale Bildanalyse

    Energy Technology Data Exchange (ETDEWEB)

    Kirchner, Johannes [Allgemeines Krankenhaus Hagen gem.GmbH (Germany). Klinik fuer Diagnostische und Interventionelle Radiologie

    2010-07-01

    The training book on thorax diagnostics using image analysis is supposed to be a supplement to the usual textbooks based on comprehensive experiences of radiologists. The covered issues are the following: heart insufficiency, acute/ chronic bronchitis and pulmonary emphysema; pneumonia and tuberculosis; bronchial carcinoma; lung fibrosis, sarcoidosis and pneumoconiosis, pleural effusion and pneumothorax.

  19. Balloon-assisted enteroscopy for suspected Meckel’s diverticulum and indefinite diagnostic imaging workup

    Science.gov (United States)

    Gomes, Guilherme Francisco; Bonin, Eduardo Aimore; Noda, Rafael William; Cavazzola, Leandro Totti; Bartholomei, Thiago Ferreira

    2016-01-01

    Meckel’s diverticulum (MD) is estimated to affect 1%-2% of the general population, and it represents a clinically silent finding of a congenital anomaly in up to 85% of the cases. In adults, MD may cause symptoms, such as overt occult lower gastrointestinal bleeding. The diagnostic imaging workup includes computed tomography scan, magnetic resonance imaging enterography, technetium 99m scintigraphy (99mTc) using either labeled red blood cells or pertechnetate (known as the Meckel’s scan) and angiography. The preoperative detection rate of MD in adults is low, and many patients ultimately undergo exploratory laparoscopy. More recently, however, endoscopic identification of MD has been possible with the use of balloon-assisted enteroscopy via direct luminal access, which also provides visualization of the diverticular ostium. The aim of this study was to review the diagnosis by double-balloon enteroscopy of 4 adults with symptomatic MD but who had negative diagnostic imaging workups. These cases indicate that balloon-assisted enteroscopy is a valuable diagnostic method and should be considered in adult patients who have suspected MD and indefinite findings on diagnostic imaging workup, including negative Meckel’s scan. PMID:27803776

  20. [Imaging of the lumbosacral plexus : Diagnostics and treatment planning with high-resolution procedures].

    Science.gov (United States)

    Jengojan, S; Schellen, C; Bodner, G; Kasprian, G

    2017-03-01

    Technical advances in magnetic resonance (MR) and ultrasound-based neurography nowadays facilitate the radiologica