Hannah S. Davie
Full Text Available Bats represent one of the least studied mammal groups in Mongolia, and little is known about the distribution and ecology of species in the country. We surveyed bats in Ikh Nart Nature Reserve, which lies at the intersection of two ecozones in Mongolia, to determine the species present and obtain preliminary data on habitat associations. We conducted mist net surveys at 9 sites, including 4 at natural springs, 2 at human-made wells, and 3 at sites without water, from June to August 2011. We captured 149 individuals representing 3 species, Myotis aurascens, Eptesicus gobiensis, and Vespertilio sp. One species, E. gobiensis , represents a new record for the reserve. We captured all three species at sites near natural springs, only one species, M. aurascens, at human-made well sites, and no bats at sites without water. We also collected basic morphometric measurements for M. aurascens and E. gobiensis . Analysis of morphometric measurements for M. aurascens indicated some sexual dimorphisms. Our results provide a baseline estimate of bats in Ikh Nart and suggest that bat diversity is greater than previously thought. Our results also validate the presence of E. gobiensis and suggest that the species we captured associate mainly with natural water sources.
James D. Murdoch
Full Text Available The Daurian hedgehog ranges across northern Mongolia, southern Siberia, and northern China. However, few details of the species’ behavior, ecology, or distribution are known. We conducted a pilot study of the ranging behavior and diet of Daurian hedgehogs in Ikh Nart Nature Reserve, Mongolia. We captured and radio-tagged eight hedgehogs (six males/two females between June and September 2006. We tracked their movements until hibernation to estimate home range sizes and daytime nest characteristics. We also analyzed scats ( N = 38 to gain a preliminary understanding of the food habits of the species. During the study, we collected 237 hedgehog locations, including 91 night, 141 day, and fi ve hibernation sites. Hedgehogs were followed a mean of 53.43 ± 4.35 SE days from capture before entering hibernation. Mean home range size for seven hedgehogs was 422.72 ± 94.07 SE ha. Daytime nest sites had one, rarely two entrances, and usually occurred in rocky outcrops or at the base of shrubs. The most frequently occurring prey groups in scats included beetles (47%, cockroaches (28%, and grasshoppers (20%. Scats also included bird (3%, reptile (1%, and rodent (1% remains. Daurian hedgehogs in Ikh Nart were generally larger in size, occupied larger home ranges, and ate similar foods compared to Daurian hedgehogs in other regions. The presence of Daurian hedgehogs in Ikh Nart also represents a range extension for the species.
James D. Murdoch
Full Text Available Corsac foxes ( Vu lpes corsac and red foxes ( V. vulpes range widely across northern and central Asia, occupying a variety of arid biotopes. In Mongolia, both species live sympatrically throughout most of the country, but few details of their habitat associations exist. We examined the biotope of corsac and red foxes in Ikh Nart Nature Reserve in Dornogobi Aimag, Mongolia, which lies at the confl ue nce of steppe and semi-desert vegetation zones. We evaluated the extent to which both species occur in these two zones and the habitats within them based on locations of scats ( n = 1 ,967, opportunistic sightings ( n = 2 19, and captures ( n = 3 5 collected from August 2004 to August 2007. Corsac and red foxes occurred in both steppe and semi-desert zones and all habitat types in the reserve. However, corsacs occurred more frequently than expected in steppe zone and red foxes occurred more than expected in semi-desert zone. Corsac locations associated positively with steppe habitats, including grass, shrub, and semi-shrub plains, whereas red fox locations fell mainly in drier, more rugged semi-desert habitats, suggesting ecological separation exists between species. As corsac and red foxes appear to be declining in Mongolia, our results suggest that protection efforts in Ikh Nart should focus on steppe habitats for corsacs and semi-desert habitats for red foxes.
Full Text Available Spatially-explicit wildlife habitat models are increasingly used to study optimal habitat for species of conservation focus. A ruggedness layer, that summarizes aspect and slope, provides a useful tool for analyses conducted in a Geographic Information System (GIS, such as developing a habitat suitability index model to measure species habitat use. Ruggedness layers prove especially useful in areas where topography represents a key habitat component. We created a ruggedness layer for the Ikh Nart Nature Reserve and surrounding areas in northern Dornogobi Aimag (province, Mongolia. Using a 90 m Shuttle Radar Topography Mission (SRTM digital elevation model (DEM and ArcGIS 10 spatial analyst, we created 9 categories for ruggedness. When combined with other thematic layers such as vegetation, the ruggedness layer becomes a powerful tool for analyzing habitat use by individual animals. The results of such analyses may inform decision makers in protected area planning and conservation of endangered species.
Full Text Available We examined home range characteristics and habitat selection of Daurian hedgehogs in Ikh Nart Nature Reserve, Mongolia. Home ranges of hedgehogs varied from 113.15 ha to 2,171.97 ha, and were larger in early summer than late summer. Hedgehogs showed relative preference for rocky outcrops and low-density shrub habitats, and relative avoidance of high- density shrub areas. Habitat selection also changed between early and late summer, shifting to greater use of low-density shrub areas and decreased use of forb-dominated short grass. Our baseline data on home ranges and habitat selection expand understanding of hedgehog ecology and provide guidance for future management decisions in Ikh Nart Nature Reserve and elsewhere in Mongolia.
James D. Murdoch
Full Text Available Species’ distributions refl ect the quality of landscape conditions, and represent an important component of protected area management. However, distributions are diffi cult to estimate, and consequently, often determined through a combination of limited fi eld data and expert opinion, which may lead to biases. We demonstrate the use of occupancy models to map distributions and estimate landscape quality. We used occupancy models for two species, the red fox and toad-headed agama, to map their distributions in Ikh Nart Nature Reserve located in southeastern Mongolia. We then used occupancy probability as a measure of quality and tested whether differences existed in quality between three areas: 1 inside the reserve, 2 inside the reserve’s core protected area, and 3 outside the reserve, using 30 sample sites in each. Occupancy probability varied from 0.084 to 0.997 for red foxes and 0.022 to 0.949 for agamas in maps. Landscape quality was highest in the core area and lowest outside the reserve for red foxes, and highest outside the reserve and lowest in the core area for agamas. Our results provide visual depictions of distributions across the Ikh Nart landscape and a means of assessing the quality of the Ikh Nart protected area that may inform management activities.
James D. Murdoch
Full Text Available Understanding how animals move through a landscape can reveal corridors or narrow paths of movement that connect discrete parts of a landscape. Identifying corridors can be important for planning conservation activities, especially for threatened species. We synthesized information on the ranging behavior and distribution of argali sheep to quantify linkages and potential pinch points of movement between critical resources in Ikh Nart Nature Reserve, Mongolia. We used a cost-weighted distance approach to quantify the relative cost of movement between water sources (springs, which represent critical resources. We used values to map a corridor of movement and examined movement fl ow through the corridor using a circuit theory approach. We identifi ed a corridor connecting all springs that covered 50.6 km2 . Most of the corridor overlapped the reserve (77% and reserve’s core area (62%. A least-cost path between the furthest separated springs (18 km was 26.4 km. Most movement fl ow through the corridor concentrated around springs, especially those in the southern and central portions of the corridor. The analysis also revealed several pinch points that represent a conservation concern. We recommend prioritizing activities at pinch points and extending protected area boundaries to encompass all springs to eff ectively protect the entire corridor.
Full Text Available Changes in red fox home range size in relation to environmental and intrinsic factors were studied using radio-telemetry during 2006–2008 in Ikh Nart Nature Reserve, southeastern Mongolia. We captured a total of 12 red foxes (8 females and 4 males and fi tted them with VHF radio-collars. Marked animals were tracked up to fi ve times a week to estimate home ranges. We also trapped small mammal and insects in different biotopes for 3 years to estimate relative abundance of prey. Our results showed that mean individual home range sizes varied widely and differed among years. There was variation in home ranges between adults versus juveniles, but no signifi cant difference was found between males versus females. In addition, mean home range size did not differ seasonally for pooled years. Variation in home ranges was best explained by a model that included covariates of year and age. We suggest that spatiotemporal changes in resource availability across years infl uenced home range dynamics of red foxes in our study.
Full Text Available Understanding the factors infl uencing survival of ungulate neonates facilitates successful management programs, particularly as they relate to population dynamics and adaptive species management. However, kid survival of near threatened Siberian ibex (Capra sibirica remains poorly understood. During 2005-2013, we captured and collared 21 ibex kids in Ikh Nart Nature Reserve in southeastern Mongolia, to monitor their survival and cause-specifi c mortality. We found no diff erences in morphometric measurements between male and female kids, except body mass being males weighing more than females. A total of 11 mortalities were documented and predations by red foxes (n=5, Vulpes vulpes and grey wolf (n=1, Canis lupus was the leading cause of the mortalities. Known fate models indicate the monthly survival of kids best explained by body mass and fi rst month of life (April-May + weight. Monthly survival estimates ranged from 0.077 (95% CI = 0.60-0.88 in April-May to 0.97 (95% CI = 0.90-0.99 in June-March, with an annual survival rate of 0.45 (95% CI = 0.24-0.68. We found little support for the hypotheses that body mass or birth date infl uenced survival; however, our small sample size limited the power of the analyses. Overall, our results indicated that predation and other factors led to high kid mortality during the period shortly after birth
Richard P. Reading
Full Text Available Siberian ibex ( Capra sibirica remain poorly understood, as little is known about their ecology . W e began studying ibex in Ikh Nart Nature Reserve, Dornogobi Aimag, Mongolia to better understand the species’ ecological needs and threats. In this paper we report on home range and core range sizes. We captured 27 ibex and fi t them with radio telemetry collars using drive nets for adults and juveniles ( n = 22 and hand captures for neonatal kids ( n = 5 . W e collected 1,029 locations from September 2003 to February 2007. Throughout the study, 9 ibex with 40+ fi xe s used mean, annual home range sizes of 3,115.5 ± 504.2 ha using the Minimum Convex Polygon method. Home ranges calculated using the fi xe d kernel method were smaller: 475.9 ± 14.7 ha for 50% kernel and 1,808.0 ± 88.1 ha for 95% kernel. Ibex from different demographic groups (males vs. females and juveniles vs. adults used remarkably similar home and core ranges; we found no signifi ca nt differences among any demographic groups. Although not quantifi ed , ibex mostly restricted their activities to areas with steep cliffs and rocky outcrops and home ranges overlapped extensively.
David E. Kenny
Full Text Available In the spring of 2009 (April/May the Denver Zoological Foundation in collaboration with the Mongolian Academy of Sciences conducted a fi eld coprological assessment feasibility study at the Ikh Nart Nature Reserve in southeastern Mongolia. Our initial effort was directed at fi nding simple methodologies that would work consistently in the fi eld for identifying some of the enteric parasites for argali sheep ( Ovis ammon and Siberian ibex ( Capra sibirica , and then to compare these to samples from local nomad domestic fat-tailed sheep ( Ovis aries and cashmere goats ( Capra hircus . Direct fecal examination yielded less eggs than the fl otation techniques, but was still felt to be useful as a quick screening tool. From the fl otation techniques we settled on using sugar because it appeared to yield the most eggs and sugar is readily available in Mongolia. We successfully recovered Entamoeba sp., Eimeria spp., trichostrongyles, large trichostrongyle species, Trichuris ovis and Strongyloides papillosus . We are using the digital images we captured to create a fi eld guide for common enteric parasites found in wildlife and domestics ungulates found in the reserve. In the future, we plan to use the fi eld guide and the quantitative modi fi ed McMaster technique to compare parasite egg-type numbers in both wild and domestic ungulates during different seasons.
O B Ershova
Full Text Available Aim: Study offactors influencing on the fractures of proximal femur not connected with osteoporosis. Material and methods: Study is based on the simultaneous and prospective clinical-epidemiological study in patients of Yaroslavl aged 50 and more with proximal femoral fractures. Radiological method of assessment of femoral fractures followed by radiomorphological analysis of hip joints radiographs was used. Control group standardized by sex and age included persons without fractures and was numbered twice more than experimental group. Results: In 132 out of 133 cases the fractures were connected with falling down and only in one case with lifting the load. Accidental falling in males were reliably more frequent as compared with other reasons of falling (p=0.03. In females the fallings connected with cardiovascular diseases and cerebral disturbances reliably prevailed. Decreasing of points in psychodiagnostic test (MMST lower than 24 is the risk factor of fallings (OP-3.022, p<0.01. Conclusion: Aside from osteoporotic process during femoral fractures one should consider other factors, such as anatomical peculiarities of proximal femur, body mass, height and concomitant diseases.
Zabramnyy, D.T.; Pobedonosteva, O.I.; Pobedonostseva, N.I.; Umarov, T.Z.
This monograph gives the results of research into the molecular structure of humic acids; certain issues are examined of an applied nature; the data from experimental industrial tests are generalized. Data are generalized which involve questions of the use of humic acids in the form of multiple-ton product. In agriculture, they are used for producing final complex fertilizers and plant growth stimulators; in drilling technology, for improving drilling muds; in the cement industry, for lowering the moisture content of cement raw material sludges. Methods of modifying humates by sulfomethylation are described, and a method for producing coal-alkali reagents directly at drilling and cement firms, based on intensifying the process of interaction of coals with alkali solutions.
especially of organic and ammonium nitrogen phosphorus, carbohydrates and aminoacids than coniferous ones (pine). The data obtained can be used when predicting the conditions of new and existing water basins. (Author)
Zhuravel', A. V.
The overwhelming majority of Old-Russian dates are Julian, and this fact seems to prove that the Julian calendar gained a foothold after the baptism of Rus'. However, there are also about 10 lunar datings (mainly from the XV c.) in Russian chronicles. This fact corresponds to the words of Kirik (the Novgorod mathematician of the XII c.) who distinguished "heavenly" months from "literary" ones. The research shows that Kirik's words are true for the entire Medieval period of Russian history: the Julian calendar was really the "literary" one and people continued to count days by the Moon in their day-to-day life. Thus, lunar dating came up in Russian chronicles again and again. That is why attempts of recalculation into the Julian manner generated many mistakes (variant readings). If we take into account these "traces", we can reconstruct the initial lunar dating and determine more precisely the course of historical events.
A set of parameters is examined which characterizes the properties of the sum of geometrical objects which make up the structure of the pore space of oil and gas collector rocks. The properties of the structures such as the mutual disposition of individual objects, the relationships of their dimensions, the complexity of form and the presence of the predominate orientation of the objects in the plane are also evaluated. The possibility of using the measured parameters for classifying structures is shown.
CERTAIN GEOLOGICAL AND GEOPHYSICAL FACTS AND THEIR INTERPRETATION IN RELATION TO THE EARTH’S CRUSTAL COMPOSITION AND STRUCTURE (NEKOTORYE GEOLOGICHESKIE I GEOFIZICHESKIE FAKTY I IKH INTERPRETATSIYA V OTNOSHENII SOSTAVA I STROENIYA ZEMNOI KORY),
STRUCTURAL GEOLOGY, LITHOSPHERE), (*ROCK, ELASTIC PROPERTIES), MOHOROVICIC DISCONTINUITY, PETROGRAPHY, GRAVITY, ANOMALIES, OCEAN BOTTOM SAMPLING, FELDSPAR, METAMORPHIC ROCK, BASALT, SEISMIC WAVES, USSR
米彦霞; 李云春; 龙亚红; 解朋
研究一种~(125)I直接标记特异性溶瘤重组腺病毒KH901的简便高效的方法,以及评价~(125)I-KH901的体内生物学行为.采用N-溴代琥珀酰亚胺(NBS)方法对KH901进行标记,确定最佳标记条件;用凝胶过滤层析法对标记物进行分离纯化,纸层析法测定放化纯度.对~(125)I-KH901进行正常小鼠体内生物学分布检测.结果显示,~(125)I-KH901的放化纯达到95%以上,标记率可达到78%;正常小鼠尾静脉注射~(125)I-KH901后体内分布显示肝脏中放射性浓集度最高,24 h检测肝脏仍有较多放射性滞留,可达13.34 %ID/g,标记物在肾脏的摄取也较高,为8.06% ID/g. 因此, N-溴代琥珀酰亚胺(NBS)方法是一种步骤简便、标记率高的比较理想的碘标记病毒方法,~(125)I-KH901主要分布在肝脏和肾脏.%In this research was developed high efficiency method using ~(125)I for directly labeling KH901,a tumor-specific oncolytic recombinant adenovirus,biodistribution of ~(125)I-labeled compound in normal mice was investigated. ~(125)I-KH901 was prepared by N-bromosuccinimide labeling method to find the optimal ratio of labeling response. The compounds were isolated and purified by Sephadex-G10 agarose and the radiochemical purity of compounds was analyzed by paper chromatography. The radioactivity biodistribution in mice was measured at different times after caudal vein injection with 0.1ml ~(125)I-KH901. The labeling yield of ~(125)I-KH901 was 78% and the radiochemical purity was 95% after purification by Sephadex-G10 agarose. Biodistribution revealed that the uptake of ~(125)I-KH901 in liver was higher than in other organs at all time points of the experiment. ~(125)I-KH901 was mainly concentrated in liver,kidneys,spleen and lung. It can be seen that N-bromosuccinimide labeling method is an optimal method with simple steps and high labeling yield in labeling KH901 with ~(125)I. ~(125)I-KH901 has a biodistribution trait which is an advantage to treating liver
Wesley M. Sarmento
Full Text Available Community-based conservation approaches that keep people on landscapes increasingly complement preservationist models of reserves without people. Evaluations of community conservation have shown that economic incentives and socioeconomics primarily drive people’s attitudes and perceptions. Work at Mongolia’s Ikh Nart Nature Reserve demonstrates how to achieve successful conservation by integrating local people into the overall program. Using a short questionnaire, we interviewed pastoralist families across two soums (similar to a U.S. county in Ikh Nart. We examined (1 pastoralists’ perceived threats to argali sheep (Ovis ammon, (2 socioeconomic differences among pastoralists, and (3 differences between pastoralists from different soums. We found that 15 years of conservation activities—education, research, and modest ecotourism—that occurred in the northern soum led to influences on people’s perceptions toward argali conservation. Compared with pastoralists from southern Ikh Nart, pastoralists from the northern part of the reserve more likely knew that argali are protected and understood primary threats to the species. Socioeconomic factors, such as age, sex, and wealth, did not significantly influence responses. The negligible economic incentives in Ikh Nart did not lead to response differences. Our results demonstrate that conservation can influence people across socioeconomic classes without providing large economic incentives.
Inhibitory Activity of Lactid Acid Bacteria Isolated from Tape Waterlily Seed to Enteric Pathogenic Bacteria (Vibrio cholera, Salmonella typhi, Shigella disentri, and E.coli and Its’ Susceptibility to Antibiotic, Bile Salt and Acidic Condition
Iin Khusnul Khotimah
Full Text Available The aim of this research was to observe inhibitory activity of LAB isolated from tape waterlily seed to enteric pathogenic bacteria (Vibrio cholera, Salmonella typhi, Shigella disentri, E.coli ATCC 25922 and it’s susceptibility to antibiotic, in bile salt and under acidic condition. Microbia in the tape ( a fermented product of waterlily seed to showed were Streptococcus thermophilus (IKH-1, Pediococcus pentosaceus (IKH-2 and Leuconostoc mesentroides (IKH-8. Streptococcus thermophillus showed inhibition against the growth of Shigella disentri with inhibition zones 16,28 mm, but did not against the growth of V. Cholera, S. typhi, E.coli. Pediococcus pentosaceus inhibit Vibrio cholera, dan Salmonella thypi with inhibition zones 18,59 mm dan 7,91 mm. So that, Leuconostoc mesenteroides inhibit Salmonella thypi with zones inhibits average 8,25 mm. Chloramfenicol at 0.05 mg concentrations did not show inhibition against the growth of isolated Streptococcus thermophillus, Pediococcus pentosaceus and Leuconostoc mesentroides. These isolates could survive too in bile salt (2% and acidified media (pH 3. Keyword : The tape of waterlily seed, LAB, probiotic and enteric pathogenic KEMAMPUAN PENGHAMBATAN BAKTERI ASAM LAKTAT DARI TAPE BIJI TERATAI TERHADAP PATOGENIK ENTERIK (VIBRIO CHOLERA, SALMONELLA THYPI, SHIGELLA DISENTRI, E. COLI, ANTIBIOTIK, KETAHANANNYA TERHADAP BILE SALT DAN ASAM ABSTRAK Penelitian ini bertujuan untuk menguji kemampuan penghambatan bakteri asam laktat yang diisolasi dari tape biji teratai terhadap patogenik enterik (Vibrio cholera, Salmonella thypi, Shigella disentri, E. Coli ATCC 25922, antibiotik, bile salt dan asam. Jenis bakteri yang diketahui tumbuh selama fermentasi tape biji teratai adalah Streptococcus thermopilus (IKH-1, Pediococcus pentosaceus(IKH-2, dan Leuconostoc mesentroides (IKH-8. Pengamatan terhadap uji penghambatan patogenik enterik (Vibrio cholera, Salmonella thypi, Shigella disentri, dan E. Coli ATCC
Ekernas, L Stefan; Sarmento, Wesley M; Davie, Hannah S; Reading, Richard P; Murdoch, James; Wingard, Ganchimeg J; Amgalanbaatar, Sukh; Berger, Joel
In arid regions of the developing world, pastoralists and livestock commonly inhabit protected areas, resulting in human-wildlife conflict. Conflict is inextricably linked to the ecological processes shaping relationships between pastoralists and native herbivores and carnivores. To elucidate relationships underpinning human-wildlife conflict, we synthesized 15 years of ecological and ethnographic data from Ikh Nart Nature Reserve in Mongolia's Gobi steppe. The density of argali (Ovis ammon), the world's largest wild sheep, at Ikh Nart was among the highest in Mongolia, yet livestock were >90% of ungulate biomass and dogs >90% of large-carnivore biomass. For argali, pastoral activities decreased food availability, increased mortality from dog predation, and potentially increased disease risk. Isotope analyses indicated that livestock accounted for >50% of the diet of the majority of gray wolves (Canis lupus) and up to 90% of diet in 25% of sampled wolves (n = 8). Livestock composed at least 96% of ungulate prey in the single wolf pack for which we collected species-specific prey data. Interviews with pastoralists indicated that wolves annually killed 1-4% of Ikh Nart's livestock, and pastoralists killed wolves in retribution. Pastoralists reduced wolf survival by killing them, but their livestock were an abundant food source for wolves. Consequently, wolf density appeared to be largely decoupled from argali density, and pastoralists had indirect effects on argali that could be negative if pastoralists increased wolf density (apparent competition) or positive if pastoralists decreased wolf predation (apparent facilitation). Ikh Nart's argali population was stable despite these threats, but livestock are increasingly dominant numerically and functionally relative to argali. To support both native wildlife and pastoral livelihoods, we suggest training dogs to not kill argali, community insurance against livestock losses to wolves, reintroducing key native prey species
Stuart Arthur Friedberg Submitted in Parual Fulfillment of the Requirements for the Degree Doctor of Philosophy Supervised by Thomas J. LeBtenc...award of the degree Doctor of Philosophy from the University of Rochester in October 1988. "\\ Accession For NTTS Orkkl DT1C Ikh Utmnaourieod...MuJ78] T. Mukaihaia and R. D. Johnstone, Implementation and Use of Small Automated- Tesi Systems, Proceedings of the IEEE 66,4 (April 1978), 403-413
Rob Roy Ramey II
Full Text Available Ar gali sheep ( Ovis ammon were live captured for radio-collaring using horsemen as the primary means to herd them into drive nets. Two adult ar gali ewes, one ar gali lamb, and one adult ibex ewe were captured by drive-netting in five days ef fort in Ikh Nartiin Chuluu Nature Reserve, Mongolia, in September 2002. This represents the first use of this low tech, ef ficient, and low cost method for live capture of argali.
Full Text Available CH (Link to library) CHP591 (Link to dictyBase) - - - Contig-U16260-1 CHP591P (Link to Original site) CHP...591F 629 CHP591Z 509 CHP591P 1118 - - Show CHP591 Library CH (Link to library) Clone ID CHP...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CH/CHP5-D/CHP591Q.Seq.d/ Representative seq. ID CHP...591P (Link to Original site) Representative DNA sequence >CHP591 (CHP591Q) /CSM/CH/CHP5-D/CHP...lrtnrncitssrr*tyqtslirqqsrsflirtp ikh*rslslfp*sy*irqchcw*h*--- ---ngppkkgvvl**kherypfqsl*chpph*chpxrwwsnhpnc
Yu. V. Muravyev
Full Text Available Ingibitory faktora nekroza opukholi α (FNO α – infliksimab, adalimumab i etanertsept – k aprelyu 2009 g. poluchili bolee 2 mln bol'nykh vo vsem mire. Vse eti preparaty okazalis' odinakovo effektivny (okolo 60% bol'nykh otvetili na lechenie pri revmatoidnom artrite (RA, ankiloziruyushchem spondilite (AS, psoriaze, psoriaticheskom artrite i odobreny dlya lecheniya etikh boleznei [1, 2]. Odnako ikh ispol'zovanie mozhet byt' svyazano s tselym ryadom neblagopriyatnykh reaktsii, odnoi iz kotorykh yavlyaetsya obostrenie ili razvitie novykh sluchaev psoriaza .
Full Text Available Little information exists on the isotopic signatures of plants and animals in Mongolia, limiting the application of stable isotope analysis to wildlife biology studies. Here we present plant and mammal carbon (δ 13 C and nitrogen (δ 15 N isotope values from a desert-steppe region of southeastern Mongolia. We analyzed 11 samples from 11 plant species and 93 samples from 24 mammal species across Ikh Nart Nature Reserve, and compared these numbers to isotope values reported from other areas of Mongolia. Our plant and mammal 13 C and 15 N values were similar to those from a similar arid steppe region and more enriched than those from less arid habitats. Habitat variation within and between study sites has an important infl uence on δ 13 C and δ 15 N variation. Our results supplement current knowledge of isotopic variation in Mongolia and provide a reference for future stable isotope research in Mongolia and similar Asian steppe ecosystems.
Laura; A; Perez-Casellas; Aleksandar; Savic; Sinisa; Dovat
Through alternate splicing,the Ikaros gene produces multiple proteins.Ikaros is essential for normal hematopoiesis and possesses tumor suppressor activity.Ikaros isoforms interact to form dimers and potentially multimeric complexes.Diverse Ikaros complexes produced by the presence of different Ikaros isoforms are hypothesized to confer distinct functions.Small dominantnegative Ikaros isoforms have been shown to inhibit the tumor suppressor activity of full-length Ikaros.Here,we describe how Ikaros activity is regulated by the coordinated expression of the largest Ikaros isoforms IK-1 and IK-H.Although IK-1 is described as full-length Ikaros,IK-H is the longest Ikaros isoform.IK-H,which includes residues coded by exon 3B (60 bp that lie between exons 3 and 4),is abundant in human but not murine hematopoietic cells.Specific residues that lie within the 20 amino acids encoded by exon 3B give IK-H DNA-binding characteristics that are distinct from those of IK-1.Moreover,IK-H can potentiate or inhibit the ability of IK-1 to bind DNA.IK-H binds to the regulatory regions of genes that are upregulated by Ikaros,but not genes that are repressed by Ikaros.Although IK-1 localizes to pericentromeric heterochromatin,IK-H can be found in both pericentromeric and non-pericentromeric locations.Anti-silencing activity of gamma satellite DNA has been shown to depend on the binding of IK-H,but not other Ikaros isoforms.The unique features of IK-H,its influence on Ikaros activity,and the lack of IK-H expression in mice suggest that Ikaros function in humans may be more complex and possibly distinct from that in mice.
khukhuudei, Ulambadrakh; otgonbayar, Orolzodmaa
- K-Ar age for Mesozoic volcanic rocks from Eastern Mongolia and Ikh Khyangan dated in range from 160 to 110Ma (Shuvalov, 1987; Makhbadar et al., 1995; Zhou et al., 2006; Bat-Ulzii, 2014). 2. Rift controlling fault - Delgerekh, Modon Ovoo and Matad faults to north-east direction are interpreted and presented in EMP (Khasin, 1973; Tikhonov, 1974; Byamba, 2009). 3. Basin and Range topography - we are interpreting that Nukhet davaa mountain range, Tamsag basin, Matad uplift or range and Choibalsan basin were developed in that time. Hills with 40-150 m height at a present day are interpreted that they developed from the Late Cretaceous period. In post- rift or Late Cretaceous period, lakes disappeared and whole area of Eastern Mongolia became a dry land, dominating by exogenic process. Denudation planation surface at EMP are kept in high and low level. High or old planation surface is proposed by age of the Miocene - Lower Pliocene and low or young planation surface - Late Pliocene. Just a current topography of EMP is formed in Late Neogene - Lower Quaternary period as a peneplain.