Invariant and Absolute Invariant Means of Double Sequences

Directory of Open Access Journals (Sweden)

Abdullah Alotaibi

2012-01-01

Full Text Available We examine some properties of the invariant mean, define the concepts of strong σ-convergence and absolute σ-convergence for double sequences, and determine the associated sublinear functionals. We also define the absolute invariant mean through which the space of absolutely σ-convergent double sequences is characterized.

Deducing T, C, and P invariance for strong interactions in topological particle theory

International Nuclear Information System (INIS)

Jones, C.E.

1985-01-01

It is shown here how the separate discrete invariances [time reversal (T), charge conjugation (C), and parity (P)] in strong interactions can be deduced as consequences of other S-matrix requirements in topological particle theory

"Invariant Mass Distribution of Jet Pairs Produced in Association with a W Boson in $p\\bar{p}$ Collisions at $\\sqrt{s}$ 1.96 TeV"

CERN Multimedia

CERN. Geneva

2011-01-01

We present a study of the invariant mass distribution of jet pairs produced in association with a W boson using data collected with the CDF detector which correspond to an integrated luminosity of 4.3 fb$^{−1}$. The observed distribution has an excess in the 120-160 GeV/c$^{2}$ mass range which is not described by current theoretical predictions within the statistical and systematic uncertainties. In particular we will discuss the properties of this excess.

Minimality of invariant laminations for partially hyperbolic attractors

International Nuclear Information System (INIS)

Nobili, Felipe

2015-01-01

Let f : M → M be a C 1 -diffeomorphism over a compact boundaryless Riemannian manifold M, and Λ a compact f-invariant subset of M admitting a partially hyperbolic spliting T f Λ = E s  ⊕ E c  ⊕ E u over the tangent bundle T f Λ. It's known from the Hirsch–Pugh–Shub theory that Λ admits two invariant laminations associated to the extremal bundles E s and E u . These laminations are families of dynamically defined immersed submanifolds of the M tangent, respectively, to the bundles E s and E u at every point in Λ. In this work, we prove that at least one of the invariant laminations of a transitive partially hyperbolic attractor with a one-dimensional center bundle is minimal: the orbit of every leaf intersects Λ densely. This result extends those in Bonatti et al (2002 J. Inst. Math. Jussieu 1 513–41) and Hertz et al (2007 Fields Institute Communications vol 51 (Providence, RI: American Mathematical Society) pp 103–9) about minimal foliations for robustly transitive diffeomorphisms. (paper)

Invariant cross sections for the inclusive reactions antipp→π++X and antipp→p+X at 22.4 GeV/c

International Nuclear Information System (INIS)

Boss, E.G.; Ermilova, D.I.; Samojlov, V.V.

1978-01-01

The invariant inclusive cross sections for π + mesons and protons from antipp reactions at 22.4 GeV/c are presented. The average multiplicity for π + meson and proton production is 1.92+-0.02 and 0.41+-0.02, respectively. The annihilation spectra have been approximated using the difference between antipp and pp data. The resulting distributions have similar features as the total antipp data

Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41.

Directory of Open Access Journals (Sweden)

Tana Taechalertpaisarn

Full Text Available The genomes of Plasmodium parasites that cause malaria in humans, other primates, birds, and rodents all encode multiple 6-cys proteins. Distinct 6-cys protein family members reside on the surface at each extracellular life cycle stage and those on the surface of liver infective and sexual stages have been shown to play important roles in hepatocyte growth and fertilization respectively. However, 6-cys proteins associated with the blood-stage forms of the parasite have no known function. Here we investigate the biochemical nature and function of two blood-stage 6-cys proteins in Plasmodium falciparum, the most pathogenic species to afflict humans. We show that native P12 and P41 form a stable heterodimer on the infective merozoite surface and are secreted following invasion, but could find no evidence that this complex mediates erythrocyte-receptor binding. That P12 and P41 do not appear to have a major role as adhesins to erythrocyte receptors was supported by the observation that antisera to these proteins did not substantially inhibit erythrocyte invasion. To investigate other functional roles for these proteins their genes were successfully disrupted in P. falciparum, however P12 and P41 knockout parasites grew at normal rates in vitro and displayed no other obvious phenotypic changes. It now appears likely that these blood-stage 6-cys proteins operate as a pair and play redundant roles either in erythrocyte invasion or in host-immune interactions.

Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain.

Directory of Open Access Journals (Sweden)

Alexandra J Spencer

Full Text Available The orthodox role of the invariant chain (CD74; Ii is in antigen presentation to CD4+ T cells, but enhanced CD8+ T cells responses have been reported after vaccination with vectored viral vaccines encoding a fusion of Ii to the antigen of interest. In this study we assessed whether fusion of the malarial antigen, ME-TRAP, to Ii could increase the vaccine-induced CD8+ T cell response. Following single or heterologous prime-boost vaccination of mice with a recombinant chimpanzee adenovirus vector, ChAd63, or recombinant modified vaccinia virus Ankara (MVA, higher frequencies of antigen-specific CD4+ and CD8+ T cells were observed, with the largest increases observed following a ChAd63-MVA heterologous prime-boost regimen. Studies in non-human primates confirmed the ability of Ii-fusion to augment the T cell response, where a 4-fold increase was maintained up to 11 weeks after the MVA boost. Of the numerous different approaches explored to increase vectored vaccine induced immunogenicity over the years, fusion to the invariant chain showed a consistent enhancement in CD8+ T cell responses across different animal species and may therefore find application in the development of vaccines against human malaria and other diseases where high levels of cell-mediated immunity are required.

On functional bases of the first-order differential invariants for non-conjugate subgroups of the Poincaré group $P(1,4$

Directory of Open Access Journals (Sweden)

V.M. Fedorchuk

2008-11-01

Full Text Available It is established which functional bases of the first-order differential invariants of the splitting and non-splitting subgroups of the Poincaré group $P(1,4$ are invariant under the subgroups of the extended Galilei group $widetilde G(1,3 subset P(1,4$. The obtained sets of functional bases are classified according to dimensions.

Substance Use and Depression Symptomatology: Measurement Invariance of the Beck Depression Inventory (BDI-II among Non-Users and Frequent-Users of Alcohol, Nicotine and Cannabis.

Directory of Open Access Journals (Sweden)

Ashlee A Moore

Full Text Available Depression is a highly heterogeneous condition, and identifying how symptoms present in various groups may greatly increase our understanding of its etiology. Importantly, Major Depressive Disorder is strongly linked with Substance Use Disorders, which may ameliorate or exacerbate specific depression symptoms. It is therefore quite plausible that depression may present with different symptom profiles depending on an individual's substance use status. Given these observations, it is important to examine the underlying construct of depression in groups of substance users compared to non-users. In this study we use a non-clinical sample to examine the measurement structure of the Beck Depression Inventory (BDI-II in non-users and frequent-users of various substances. Specifically, measurement invariance was examined across those who do vs. do not use alcohol, nicotine, and cannabis. Results indicate strict factorial invariance across non-users and frequent-users of alcohol and cannabis, and metric invariance across non-users and frequent-users of nicotine. This implies that the factor structure of the BDI-II is similar across all substance use groups.

Substance Use and Depression Symptomatology: Measurement Invariance of the Beck Depression Inventory (BDI-II) among Non-Users and Frequent-Users of Alcohol, Nicotine and Cannabis.

Science.gov (United States)

Moore, Ashlee A; Neale, Michael C; Silberg, Judy L; Verhulst, Brad

2016-01-01

Depression is a highly heterogeneous condition, and identifying how symptoms present in various groups may greatly increase our understanding of its etiology. Importantly, Major Depressive Disorder is strongly linked with Substance Use Disorders, which may ameliorate or exacerbate specific depression symptoms. It is therefore quite plausible that depression may present with different symptom profiles depending on an individual's substance use status. Given these observations, it is important to examine the underlying construct of depression in groups of substance users compared to non-users. In this study we use a non-clinical sample to examine the measurement structure of the Beck Depression Inventory (BDI-II) in non-users and frequent-users of various substances. Specifically, measurement invariance was examined across those who do vs. do not use alcohol, nicotine, and cannabis. Results indicate strict factorial invariance across non-users and frequent-users of alcohol and cannabis, and metric invariance across non-users and frequent-users of nicotine. This implies that the factor structure of the BDI-II is similar across all substance use groups.

Invariant cross sections for inclusive reactions anti pp→π++X and anti pp→p+X at 22.4 GeV/c

International Nuclear Information System (INIS)

Boos, E.G.; Temiraliev, T.; Samojlov, V.V.

1977-01-01

Invariant inclusive cross sections for π + mesons and protons from antipp reactions at 22.4 GeV/c are presented. The average multiplicity for production of π + mesons is 1.92+-0.02 and for protons 0.41+-0.02. Annihilation spectra have been approximated by using the difference between antipp and pp data. The resulting distributions have similar gross features as the total antipp data. (author)

41Ar-concentration measurements at the Finnish TRIGA Mark II

International Nuclear Information System (INIS)

Tamminen, A.

1970-01-01

41 Ar-concentrations in the reactor hall and in the Ar-ventilation duct of FiR-1 (IRIGA Mark II, 250 kW) have been measured during normal operation conditions. Additional measurements have been performed varying Ar-ventilation and hall ventilation flow. A γ- and background compensated thin window proportional detector and a β-Geiger detector for 41 Ar-measurements are described. The hall concentration has also been estimated from background measurements with an unshielded Ge(Li)-detector. The saturation concentration in the reactor hall with and without the hall ventilation is about 1 x 10 -7 μCi/cm 3 and 3 x 10 -7 μCi/cm 3 , respectively. (author)

Classification of simple current invariants

CERN Document Server

Gato-Rivera, Beatriz

1992-01-01

We summarize recent work on the classification of modular invariant partition functions that can be obtained with simple currents in theories with a center (Z_p)^k with p prime. New empirical results for other centers are also presented. Our observation that the total number of invariants is monodromy-independent for (Z_p)^k appears to be true in general as well. (Talk presented in the parallel session on string theory of the Lepton-Photon/EPS Conference, Geneva, 1991.)

Conformal Invariance, Dark Energy, and CMB Non-Gaussianity

CERN Document Server

Antoniadis, Ignatios; Mottola, Emil

2012-01-01

We show that in addition to simple scale invariance, a universe dominated by dark energy naturally gives rise to correlation functions possessing full conformal invariance. This is due to the mathematical isomorphism between the conformal group of certain three dimensional slices of de Sitter space and the de Sitter isometry group SO(4,1). In the standard homogeneous, isotropic cosmological model in which primordial density perturbations are generated during a long vacuum energy dominated de Sitter phase, the embedding of flat spatial R^3 sections in de Sitter space induces a conformal invariant perturbation spectrum and definite prediction for the shape of the non-Gaussian CMB bispectrum. In the case in which the density fluctuations are generated instead on the de Sitter horizon, conformal invariance of the S^2 horizon embedding implies a different but also quite definite prediction for the angular correlations of CMB non-Gaussianity on the sky. Each of these forms for the bispectrum is intrinsic to the sym...

Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

Science.gov (United States)

Michailidou, Kyriaki; Hall, Per; Gonzalez-Neira, Anna; Ghoussaini, Maya; Dennis, Joe; Milne, Roger L; Schmidt, Marjanka K; Chang-Claude, Jenny; Bojesen, Stig E; Bolla, Manjeet K; Wang, Qin; Dicks, Ed; Lee, Andrew; Turnbull, Clare; Rahman, Nazneen; Fletcher, Olivia; Peto, Julian; Gibson, Lorna; Dos Santos Silva, Isabel; Nevanlinna, Heli; Muranen, Taru A; Aittomäki, Kristiina; Blomqvist, Carl; Czene, Kamila; Irwanto, Astrid; Liu, Jianjun; Waisfisz, Quinten; Meijers-Heijboer, Hanne; Adank, Muriel; van der Luijt, Rob B; Hein, Rebecca; Dahmen, Norbert; Beckman, Lars; Meindl, Alfons; Schmutzler, Rita K; Müller-Myhsok, Bertram; Lichtner, Peter; Hopper, John L; Southey, Melissa C; Makalic, Enes; Schmidt, Daniel F; Uitterlinden, Andre G; Hofman, Albert; Hunter, David J; Chanock, Stephen J; Vincent, Daniel; Bacot, François; Tessier, Daniel C; Canisius, Sander; Wessels, Lodewyk F A; Haiman, Christopher A; Shah, Mitul; Luben, Robert; Brown, Judith; Luccarini, Craig; Schoof, Nils; Humphreys, Keith; Li, Jingmei; Nordestgaard, Børge G; Nielsen, Sune F; Flyger, Henrik; Couch, Fergus J; Wang, Xianshu; Vachon, Celine; Stevens, Kristen N; Lambrechts, Diether; Moisse, Matthieu; Paridaens, Robert; Christiaens, Marie-Rose; Rudolph, Anja; Nickels, Stefan; Flesch-Janys, Dieter; Johnson, Nichola; Aitken, Zoe; Aaltonen, Kirsimari; Heikkinen, Tuomas; Broeks, Annegien; Veer, Laura J Van't; van der Schoot, C Ellen; Guénel, Pascal; Truong, Thérèse; Laurent-Puig, Pierre; Menegaux, Florence; Marme, Frederik; Schneeweiss, Andreas; Sohn, Christof; Burwinkel, Barbara; Zamora, M Pilar; Perez, Jose Ignacio Arias; Pita, Guillermo; Alonso, M Rosario; Cox, Angela; Brock, Ian W; Cross, Simon S; Reed, Malcolm W R; Sawyer, Elinor J; Tomlinson, Ian; Kerin, Michael J; Miller, Nicola; Henderson, Brian E; Schumacher, Fredrick; Le Marchand, Loic; Andrulis, Irene L; Knight, Julia A; Glendon, Gord; Mulligan, Anna Marie; Lindblom, Annika; Margolin, Sara; Hooning, Maartje J; Hollestelle, Antoinette; van den Ouweland, Ans M W; Jager, Agnes; Bui, Quang M; Stone, Jennifer; Dite, Gillian S; Apicella, Carmel; Tsimiklis, Helen; Giles, Graham G; Severi, Gianluca; Baglietto, Laura; Fasching, Peter A; Haeberle, Lothar; Ekici, Arif B; Beckmann, Matthias W; Brenner, Hermann; Müller, Heiko; Arndt, Volker; Stegmaier, Christa; Swerdlow, Anthony; Ashworth, Alan; Orr, Nick; Jones, Michael; Figueroa, Jonine; Lissowska, Jolanta; Brinton, Louise; Goldberg, Mark S; Labrèche, France; Dumont, Martine; Winqvist, Robert; Pylkäs, Katri; Jukkola-Vuorinen, Arja; Grip, Mervi; Brauch, Hiltrud; Hamann, Ute; Brüning, Thomas; Radice, Paolo; Peterlongo, Paolo; Manoukian, Siranoush; Bonanni, Bernardo; Devilee, Peter; Tollenaar, Rob A E M; Seynaeve, Caroline; van Asperen, Christi J; Jakubowska, Anna; Lubinski, Jan; Jaworska, Katarzyna; Durda, Katarzyna; Mannermaa, Arto; Kataja, Vesa; Kosma, Veli-Matti; Hartikainen, Jaana M; Bogdanova, Natalia V; Antonenkova, Natalia N; Dörk, Thilo; Kristensen, Vessela N; Anton-Culver, Hoda; Slager, Susan; Toland, Amanda E; Edge, Stephen; Fostira, Florentia; Kang, Daehee; Yoo, Keun-Young; Noh, Dong-Young; Matsuo, Keitaro; Ito, Hidemi; Iwata, Hiroji; Sueta, Aiko; Wu, Anna H; Tseng, Chiu-Chen; Van Den Berg, David; Stram, Daniel O; Shu, Xiao-Ou; Lu, Wei; Gao, Yu-Tang; Cai, Hui; Teo, Soo Hwang; Yip, Cheng Har; Phuah, Sze Yee; Cornes, Belinda K; Hartman, Mikael; Miao, Hui; Lim, Wei Yen; Sng, Jen-Hwei; Muir, Kenneth; Lophatananon, Artitaya; Stewart-Brown, Sarah; Siriwanarangsan, Pornthep; Shen, Chen-Yang; Hsiung, Chia-Ni; Wu, Pei-Ei; Ding, Shian-Ling; Sangrajrang, Suleeporn; Gaborieau, Valerie; Brennan, Paul; McKay, James; Blot, William J; Signorello, Lisa B; Cai, Qiuyin; Zheng, Wei; Deming-Halverson, Sandra; Shrubsole, Martha; Long, Jirong; Simard, Jacques; Garcia-Closas, Montse; Pharoah, Paul D P; Chenevix-Trench, Georgia; Dunning, Alison M; Benitez, Javier; Easton, Douglas F

2013-04-01

Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ∼9% of the familial risk of the disease. We report here a meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, from which we selected 29,807 SNPs for further genotyping. These SNPs were genotyped in 45,290 cases and 41,880 controls of European ancestry from 41 studies in the Breast Cancer Association Consortium (BCAC). The SNPs were genotyped as part of a collaborative genotyping experiment involving four consortia (Collaborative Oncological Gene-environment Study, COGS) and used a custom Illumina iSelect genotyping array, iCOGS, comprising more than 200,000 SNPs. We identified SNPs at 41 new breast cancer susceptibility loci at genome-wide significance (P breast cancer susceptibility.

Zinc(II) phthalocyanines immobilized in mesoporous silica Al-MCM-41 and their applications in photocatalytic degradation of pesticides

Energy Technology Data Exchange (ETDEWEB)

Silva, M. [Departamento de Quimica, Universidade de Coimbra, Rua Larga, 3004-535 Coimbra (Portugal); Laboratoire de Photochimie Moleculaire et Macromoleculaire, UMR CNRS 6505, Universite Blaise Pascal, F-63177 Aubiere cedex (France); Calvete, M.J.F.; Goncalves, N.P.F.; Burrows, H.D. [Departamento de Quimica, Universidade de Coimbra, Rua Larga, 3004-535 Coimbra (Portugal); Sarakha, M. [Laboratoire de Photochimie Moleculaire et Macromoleculaire, UMR CNRS 6505, Universite Blaise Pascal, F-63177 Aubiere cedex (France); Fernandes, A.; Ribeiro, M.F. [Instituto para a Biotecnologia e Bioengenharia, Centro para a Engenharia Biologica e Quimica, Instituto Superior Tecnico - Universidade Tecnica de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa (Portugal); Azenha, M.E., E-mail: meazenha@ci.uc.pt [Departamento de Quimica, Universidade de Coimbra, Rua Larga, 3004-535 Coimbra (Portugal); Pereira, M.M., E-mail: mmpereira@qui.uc.pt [Departamento de Quimica, Universidade de Coimbra, Rua Larga, 3004-535 Coimbra (Portugal)

2012-09-30

Highlights: Black-Right-Pointing-Pointer Complete immobilization of zinc(II) phthalocyanines accomplished in Al-MCM-41. Black-Right-Pointing-Pointer Efficient photodegradation of model pesticides achieved using 365 nm irradiation. Black-Right-Pointing-Pointer Sodium azide experiments showed the involvement of singlet oxygen ({sup 1}O{sub 2}). - Abstract: In the present study the authors investigated a set of three new zinc(II) phthalocyanines (zinc(II) tetranitrophthalocyanine (ZnTNPc), zinc(II) tetra(phenyloxy)phthalocyanine (ZnTPhOPc) and the tetraiodide salt of zinc(II)tetra(N,N,N-trimethylaminoethyloxy) phthalocyaninate (ZnTTMAEOPcI)) immobilized into Al-MCM-41 prepared via ship-in-a-bottle methodology. The samples were fully characterized by diffuse reflectance-UV-vis spectroscopy (DRS-UV-vis), luminescence, thermogravimetric analysis (TG/DSC), N{sub 2} adsorption techniques and elemental analysis. A comparative study was made on the photocatalytic performance upon irradiation within the wavelength range 320-460 nm of these three systems in the degradation of pesticides fenamiphos and pentachlorophenol. ZnTNPc-Al-MCM-41 and ZnTTMAEOPcI-Al-MCM-41 were found to be the most active systems, with the best performance observed with the immobilized cationic phthalocyanine, ZnTTMAEOPcI-Al-MCM-41. This system showed high activity even after three photocatalytic cycles. LC-MS product characterization and mechanistic studies indicate that singlet oxygen ({sup 1}O{sub 2}), produced by excitation of these immobilized photosensitizers, is a key intermediate in the photocatalytic degradation of both pesticides.

Zinc(II) phthalocyanines immobilized in mesoporous silica Al-MCM-41 and their applications in photocatalytic degradation of pesticides

International Nuclear Information System (INIS)

Silva, M.; Calvete, M.J.F.; Gonçalves, N.P.F.; Burrows, H.D.; Sarakha, M.; Fernandes, A.; Ribeiro, M.F.; Azenha, M.E.; Pereira, M.M.

2012-01-01

Highlights: ► Complete immobilization of zinc(II) phthalocyanines accomplished in Al-MCM-41. ► Efficient photodegradation of model pesticides achieved using 365 nm irradiation. ► Sodium azide experiments showed the involvement of singlet oxygen ( 1 O 2 ). - Abstract: In the present study the authors investigated a set of three new zinc(II) phthalocyanines (zinc(II) tetranitrophthalocyanine (ZnTNPc), zinc(II) tetra(phenyloxy)phthalocyanine (ZnTPhOPc) and the tetraiodide salt of zinc(II)tetra(N,N,N-trimethylaminoethyloxy) phthalocyaninate (ZnTTMAEOPcI)) immobilized into Al-MCM-41 prepared via ship-in-a-bottle methodology. The samples were fully characterized by diffuse reflectance-UV–vis spectroscopy (DRS-UV–vis), luminescence, thermogravimetric analysis (TG/DSC), N 2 adsorption techniques and elemental analysis. A comparative study was made on the photocatalytic performance upon irradiation within the wavelength range 320–460 nm of these three systems in the degradation of pesticides fenamiphos and pentachlorophenol. ZnTNPc-Al-MCM-41 and ZnTTMAEOPcI-Al-MCM-41 were found to be the most active systems, with the best performance observed with the immobilized cationic phthalocyanine, ZnTTMAEOPcI-Al-MCM-41. This system showed high activity even after three photocatalytic cycles. LC–MS product characterization and mechanistic studies indicate that singlet oxygen ( 1 O 2 ), produced by excitation of these immobilized photosensitizers, is a key intermediate in the photocatalytic degradation of both pesticides.

High yield production of human invariant chain CD74 constructs fused to solubility-enhancing peptides and characterization of their MIF-binding capacities

NARCIS (Netherlands)

Kok, Tjie; Wasiel, Anna A; Dekker, Frank J; Poelarends, Gerrit J; Cool, Robbert H

2018-01-01

The HLA class II histocompatibility antigen gamma chain, also known as HLA-DR antigen-associated invariant chain or CD74, has been shown to be involved in many biological processes amongst which antigen loading and transport of MHC class II molecules from the endoplasmic reticulum to the Golgi

Lorentz invariance with an invariant energy scale.

Science.gov (United States)

Magueijo, João; Smolin, Lee

2002-05-13

We propose a modification of special relativity in which a physical energy, which may be the Planck energy, joins the speed of light as an invariant, in spite of a complete relativity of inertial frames and agreement with Einstein's theory at low energies. This is accomplished by a nonlinear modification of the action of the Lorentz group on momentum space, generated by adding a dilatation to each boost in such a way that the Planck energy remains invariant. The associated algebra has unmodified structure constants. We also discuss the resulting modifications of field theory and suggest a modification of the equivalence principle which determines how the new theory is embedded in general relativity.

TEM characterization of invariant line interfaces and structural ledges in a Mo-Si alloy

International Nuclear Information System (INIS)

Xiao, S.Q.; Dahmen, U.; Maloy, S.A.; Heuer, A.H.

1995-06-01

Two distinct lath morphologies of Mo 5 Si 3 precipitates observed in MoSi 2 differ in their cross-sectional shape and lattice orientation. Type I laths exhibit a rectangular cross section, with interfaces parallel to low-index planes, while Type II laths are parallelogram-shaped, with their major interface at 13 degree to the Type I precipitate. The corresponding orientation relationships differ by a 1.8 degree rotation around the lath axis. In this study, the difference between the two characteristic morphologies and orientation relationships is shown to be the formation of an invariant line strain for Type II precipitates. On an atomic scale, both interfaces have a terrace and ledge structure but differ in the stacking sequence of interfacial ledges associated with partial dislocations. The structural unit model and the invariant line model predict identical interface geometries which agree closely with the observations

Type II diabetes mellitus and the incidence of epithelial ovarian cancer in the cancer prevention study-II nutrition cohort.

Science.gov (United States)

Gapstur, Susan M; Patel, Alpa V; Diver, W Ryan; Hildebrand, Janet S; Gaudet, Mia M; Jacobs, Eric J; Campbell, Peter T

2012-11-01

Despite consistent associations of type II diabetes mellitus with hormonally related cancers such as breast and endometrium, the relation between type II diabetes mellitus and ovarian cancer risk is unclear. Associations of type II diabetes mellitus status, duration, and insulin use with epithelial ovarian cancer overall, and with serous and nonserous histologic subtypes were examined in the Cancer Prevention Study-II Nutrition Cohort, a prospective study of U.S. men and women predominantly aged 50 years and older. Between 1992 and 2007, 524 incident epithelial ovarian cancer cases were identified among 63,440 postmenopausal women. Multivariable-adjusted relative risks (RR) and 95% confidence intervals (CI) were computed using extended Cox regression to update diabetes status and bilateral oophorectomy status during follow-up. Type II diabetes mellitus status (RR = 1.05; 95% CI, 0.75-1.46) and duration were not associated with epithelial ovarian cancer risk. Although not statistically significantly different (P(difference) = 0.39), the RR was higher for type II diabetes mellitus with insulin use (RR = 1.28; 95% CI, 0.74-2.24) than for type II diabetes mellitus without insulin use (RR = 0.96; 95% CI, 0.64-1.43). Diabetes seemed to be more strongly associated with nonserous (RR = 1.41; 95% CI, 0.70-2.85) than serous (RR = 0.71; 95% CI, 0.41-1.23) histologic subtypes. Type II diabetes mellitus was not associated with risk of epithelial ovarian cancer, although higher risks with nonserous subtypes and among insulin users cannot be ruled out. Larger studies are needed to clarify associations of type II diabetes mellitus with or without insulin use with risk of ovarian cancer overall and by histologic subtypes. ©2012 AACR.

Impulsivity and the Sexes: Measurement and Structural Invariance of the UPPS-P Impulsive Behavior Scale

Science.gov (United States)

Cyders, Melissa A.

2013-01-01

Before it is possible to test whether men and women differ in impulsivity, it is necessary to evaluate whether impulsivity measures are invariant across sex. The UPPS-P Impulsive Behavior Scale (negative urgency, lack of premeditation, lack of perseverance, and sensation seeking, with added subscale of positive urgency) is one measure of five…

Representation of magnetic fields with toroidal topology in terms of field-line invariants

International Nuclear Information System (INIS)

Lewis, H.R.

1990-01-01

Beginning with Boozer's representation of magnetic fields with toroidal topology [Phys. Fluids 26, 1288 (1983)], a general formalism is presented for the representation of any magnetic field with toroidal topology in terms of field-line invariants. The formalism is an application to the magnetic field case of results developed recently by Lewis et al. (submitted for publication to J. Phys. A) for arbitrary time-dependent Hamiltonian systems with one degree of freedom. Every magnetic field with toroidal topology can be associated with time-dependent Hamiltonian systems with one degree of freedom and every time-dependent Hamiltonian system with one degree of freedom can be associated with magnetic fields with toroidal topology. In the Hamiltonian context, given any particular function I(q,p,t), Lewis et al. derived those Hamiltonians for which I(q,p,t) is an invariant. In addition, for each of those Hamiltonians, they derived a function canonically conjugate to I(q,p,t) that is also an invariant. They applied this result to the case where I(q,p,t) is expressed as a function of two canonically conjugate functions. This general Hamiltonian formalism provides a basis for representing magnetic fields with toroidal topology in terms of field-line invariants. The magnetic fields usually contain plasma with flow and anisotropic pressure. A class of fields with or without rotational symmetry is identified for which there are magnetic surfaces. The formalism is developed for application to the case of vacuum magnetic fields

On the construction of translationally invariant deformed wave functions

International Nuclear Information System (INIS)

Guardiola, R.

1975-01-01

Translationally invariant nuclear wave functions are constructed from deformed harmonic oscillator shell-model wave functions, with an exact projection of angular momentum quantum numbers. It is shown that the computation of matrix elements with the translationally invariant wave functions is as simple as the standard calculation, and formulae are obtained for (i) the potential energy, (ii) the kinetic energy and rms radius, and (iii) the charge form factor. (Auth.)

Association of interleukin 17 / angiotensin II with refractory ...

African Journals Online (AJOL)

Table 2 Multiple linear regression analysis showing relationship between IL 17, Ang II and mean arterial pressure in hemodialysis patients. Variables. B t value. P value. IL 17. 6.320. 10.221. 0.000. Ang II. 0.143. 2.442. 0.017. Discussion. This study aimed to investigate the association between. IL 17 and the risk of refractory ...

Search for quark compositeness, axigluons, and heavy particles using the dijet invariant mass spectrum observed in p bar p collisions

International Nuclear Information System (INIS)

Abe, F.; Albrow, M.; Akimoto, H.; Amidei, D.; Anway-Wiese, C.; Apollinari, G.; Areti, H.; Auchincloss, P.; Azfar, F.; Azzi, P.; Bacchetta, N.; Badgett, W.; Bailey, M.W.; Bao, J.; de Barbaro, P.; Barbaro-Galtieri, A.; Barnes, V.E.; Barnett, B.A.; Bauer, G.; Baumann, T.; Bedeschi, F.; Behrends, S.; Belforte, S.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Benlloch, J.; Benton, D.; Beretvas, A.; Berge, J.P.; Bertolucci, S.; Bhatti, A.; Biery, K.; Binkley, M.; Bird, F.; Bisello, D.; Blair, R.E.; Blocker, C.; Bodek, A.; Bolognesi, V.; Bortoletto, D.; Boswell, C.; Boulos, T.; Brandenburg, G.; Bromberg, C.; Buckley-Geer, E.; Budd, H.S.; Burkett, K.; Busetto, G.; Byon-Wagner, A.; Byrum, K.L.; Campagnari, C.; Campbell, M.; Caner, A.; Carithers, W.; Carlsmith, D.; Castro, A.; Cen, Y.; Cervelli, F.; Chapman, J.; Chiarelli, G.; Chikamatsu, T.; Cihangir, S.; Clark, A.G.; Cobal, M.; Contreras, M.; Conway, J.; Cooper, J.; Cordelli, M.; Coupal, D.P.; Crane, D.; Cunningham, J.D.; Daniels, T.; Deninno, M.; DeJongh, F.; Dell'Agnello, S.; Dell'Orso, M.; Demortier, L.; Denby, B.; Derwent, P.F.; Devlin, T.; Dickson, M.; Done, J.P.; Drucker, R.B.; Dunn, A.; Einsweiler, K.; Elias, J.E.; Engels, E. Jr.; Ely, R.; Eno, S.; Errede, D.; Errede, S.; Etchegoyen, A.; Fan, Q.; Farhat, B.; Fiori, I.; Flaugher, B.; Foster, G.W.; Franklin, M.; Frautschi, M.; Freeman, J.; Freidman, J.; Frisch, H.; Fry, A.; Fuess, T.A.; Fukui, Y.; Funaki, S.; Garfinkel, A.F.; Geer, S.; Gerdes, D.W.; Giannetti, P.; Giokaris, N.; Giormini, P.; Gladney, L.; Glenzinski, D.; Gold, M.; Gonzalez, J.; Goshaw, A.T.; Goulianos, K.; Grassmann, H.; Grewal, A.; Grieco, G.; Groer, L.; Grosso-Pilcher, C.; Haber, C.; Hahn, S.R.; Hamilton, R.; Handler, R.; Hans, R.M.; Hara, K.; Harral, B.; Harris, R.M.; Hauger, S.A.; Hauser, J.; Hawk, C.; Heinrich, J.; Hennessy, D.; Hipple, R.; Hollebeek, R.; Hoelscher, A.; Hong, S.; Houk, G.; Hu, P.; Huston, J.; Huffman, B.T.; Hughes, R.; Hurst, P.; Huth, J.; Hylen, J.; Incagli, M.

1993-01-01

The dijet invariant mass distribution has been measured in the region between 140 and 1000 GeV/c 2 , in 1.8 TeV p bar p collisions. Data collected with the Collider Detector at Fermilab show agreement with QCD calculations. A limit on quark compositeness of Λ c >1.3 TeV is obtained. Axigluons with masses between 240 and 640 GeV/c 2 are excluded at 95% C.L. if we assume ten open decay channels. Model-independent limits on the production of heavy particles decaying into two jets are also presented

Identification of a third protein 4.1 tumor suppressor, protein 4.1R, in meningioma pathogenesis

Energy Technology Data Exchange (ETDEWEB)

Robb, Victoria A.; Li, Wen; Gascard, Philippe; Perry, Arie; Mohandas, Narla; Gutmann, David H.

2003-06-11

Meningiomas are common tumors of the central nervous system, however, the mechanisms under lying their pathogenesis are largely undefined. Two members of the Protein 4.1 super family, the neuro fibromatosis 2 (NF2) gene product (merlin/schwannomin) and Protein 4.1B have been implicated as meningioma tumor suppressors. In this report, we demonstrate that another Protein 4.1 family member, Protein 4.1R, also functions as a meningioma tumor suppressor. Based on the assignment of the Protein 4.1R gene to chromosome 1p32-36, a common region of deletion observed in meningiomas, we analyzed Protein 4.1R expression in meningioma cell lines and surgical tumor specimens. We observed loss of Protein 4.1R protein expression in two meningioma cell lines (IOMM-Lee, CH157-MN) by Western blotting as well as in 6 of 15 sporadic meningioma as by immuno histo chemistry (IHC). Analysis of a subset of these sporadic meningiomas by fluorescent in situ hybridization (FISH) with a Protein 4.1R specific probe demonstrated 100 percent concordance with the IHC results. In support of a meningioma tumor suppressor function, over expression of Protein 4.1R resulted in suppression of IOMM-Lee and CH157MN cell proliferation. Similar to the Protein 4.1B and merlin meningioma tumor suppressors, Protein 4.1R localization in the membrane fraction increased significantly under conditions of growth arrest in vitro. Lastly, Protein 4.1R interacted with some known merlin/Protein 4.1B interactors such as CD44 and bII-spectrin, but did not associate with the Protein 4.1B interactors 14-3-3 and PRMT3 or the merlin binding proteins SCHIP-1 and HRS. Collectively, these results suggest that Protein 4.1R functions as an important tumor suppressor important in the molecular pathogenesis of meningioma.

Scale-invariant transition probabilities in free word association trajectories

Directory of Open Access Journals (Sweden)

Martin Elias Costa

2009-09-01

Full Text Available Free-word association has been used as a vehicle to understand the organization of human thoughts. The original studies relied mainly on qualitative assertions, yielding the widely intuitive notion that trajectories of word associations are structured, yet considerably more random than organized linguistic text. Here we set to determine a precise characterization of this space, generating a large number of word association trajectories in a web implemented game. We embedded the trajectories in the graph of word co-occurrences from a linguistic corpus. To constrain possible transport models we measured the memory loss and the cycling probability. These two measures could not be reconciled by a bounded diffusive model since the cycling probability was very high (16 % of order-2 cycles implying a majority of short-range associations whereas the memory loss was very rapid (converging to the asymptotic value in ∼ 7 steps which, in turn, forced a high fraction of long-range associations. We show that memory loss and cycling probabilities of free word association trajectories can be simultaneously accounted by a model in which transitions are determined by a scale invariant probability distribution.

Transition probabilities for the 3s2 3p(2P0)-3s3p2(4P) intersystem lines of Si II

Science.gov (United States)

Calamai, Anthony G.; Smith, Peter L.; Bergeson, S. D.

1993-01-01

Intensity ratios of lines of the spin-changing 'intersystem' multiplet of S II (4P yields 2P0) at 234 nm have been used to determine electron densities and temperatures in a variety of astrophysical environments. However, the accuracy of these diagnostic calculations have been limited by uncertainties associated with the available atomic data. We report the first laboratory measurement, using an ion-trapping technique, of the radiative lifetimes of the three metastable levels of the 3s3p2 4P term of Si II. Our results are 104 +/- 16, 406 +/- 33, and 811 +/- 77 micro-s for lifetimes of the J = 1/2, 5/2, and 3/2 levels, respectively. A-values were derived from our lifetimes by use of measured branching fractions. Our A-values, which differ from calculated values by 30 percent or more, should give better agreement between modeled and observed Si II line ratios.

The Loneliness Questionnaire: Establishing Measurement Invariance Across Ethnic Groups.

Science.gov (United States)

Ritchwood, Tiarney D; Ebesutani, Chad K; Chin, Eu Gene; Young, John

2017-09-01

A state of loneliness describes an individual's perception of having dissatisfying social connections to others. Though it is notable across the life span, it may have particularly deleterious effects in childhood and adolescence, leading to increased risk of emotional impairment. The current study evaluates a widely used test of loneliness, the Loneliness Questionnaire, for measurement invariance across ethnic groups in a large, representative sample of youth in the 2nd to 12th grades ( N = 12,344; 41% African American) in Mississippi. Analyses were conducted using multigroup confirmatory factor analysis following a published, sequential method to examine invariance in form, factor loadings, and item intercepts. Overall, our results indicated that the instrument was invariant across ethnicities, suggesting that youth with equivalent manifest scores can be discerned as having comparable levels of latent loneliness. The loneliness scores also corresponded significantly with depression and anxiety scores for most subsamples, with one exception. These findings are discussed in the context of previous results comparing levels of loneliness across ethnicities. Additionally, the broader context of the need to expand invariance studies in instrumentation work is highlighted.

27 CFR 41.235 - Articles of partnership or association.

Science.gov (United States)

2010-04-01

... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles of partnership or... Importers of Processed Tobacco § 41.235 Articles of partnership or association. Every partnership or... application for the permit required by § 41.231 a true copy of the articles of partnership or association, if...

Maxwell equations in conformal invariant electrodynamics

International Nuclear Information System (INIS)

Fradkin, E.S.; AN SSSR, Novosibirsk. Inst. Avtomatiki i Ehlektrometrii); Kozhevnikov, A.A.; Palchik, M.Ya.; Pomeransky, A.A.

1983-01-01

We consider a conformal invariant formulation of quantum electrodynamics. Conformal invariance is achieved with a specific mathematical construction based on the indecomposable representations of the conformal group associated with the electromagnetic potential and current. As a corolary of this construction modified expressions for the 3-point Green functions are obtained which both contain transverse parts. They make it possible to formulate a conformal invariant skeleton perturbation theory. It is also shown that the Euclidean Maxwell equations in conformal electrodynamics are manifestations of its kinematical structure: in the case of the 3-point Green functions these equations follow (up to constants) from the conformal invariance while in the case of higher Green functions they are equivalent to the equality of the kernels of the partial wave expansions. This is the manifestation of the mathematical fast of a (partial) equivalence of the representations associated with the potential, current and the field tensor. (orig.)

Mucosal-Associated Invariant T Cells: New Insights into Antigen Recognition and Activation

Directory of Open Access Journals (Sweden)

Xingxing Xiao

2017-11-01

Full Text Available Mucosal-associated invariant T (MAIT cells, a novel subpopulation of innate-like T cells that express an invariant T cell receptor (TCRα chain and a diverse TCRβ chain, can recognize a distinct set of small molecules, vitamin B metabolites, derived from some bacteria, fungi but not viruses, in the context of an evolutionarily conserved major histocompatibility complex-related molecule 1 (MR1. This implies that MAIT cells may play unique and important roles in host immunity. Although viral antigens are not recognized by this limited TCR repertoire, MAIT cells are known to be activated in a TCR-independent mechanism during some viral infections, such as hepatitis C virus and influenza virus. In this article, we will review recent works in MAIT cell antigen recognition, activation and the role MAIT cells may play in the process of bacterial and viral infections and pathogenesis of non-infectious diseases.

Immunochemical studies of Lolium perenne (rye grass) pollen allergens, Lol p I, II, and III.

Science.gov (United States)

Ansari, A A; Kihara, T K; Marsh, D G

1987-12-15

It was reported earlier that human immune responses to three perennial rye grass (Lolium perenne) pollen allergens, Lol p I, II, and III, are associated with histocompatibility leukocyte antigen (HLA)-DR3. Rye-allergic people are often concordantly sensitive to all three of these allergens. Since earlier studies suggested that these antigens are non-cross-reactive, their immunologic relatedness by double antibody radioimmunoassay (DARIA) was studied in order to understand further the immunochemical basis for the concordant recognition of the three allergens. Direct binding DARIA studies were performed with human sera from 189 allergic subjects. Inhibition DARIA studies were carried out with 17 human sera from grass-allergic patients who were on grass immunotherapy, one goat anti-serum, and six rabbit antisera. None of the sera detected any significant degree of two-way cross-reactivity between Lol p I and II, or between Lol p I and III. However, the degree of two-way cross-reactivity between Lol p II and III exhibited by individual human and animal antisera varied between undetectable and 100%. In general, the degree of cross-reactivity between Lol p II and III was higher among human sera than among animal sera. Taken together with earlier findings that antibody responses to Lol p I, II and III are associated with HLA-HDR3, and that most Lol p II and III responders are also Lol p I responders, but not vice versa, our present results suggest the following: the HLA-DR3-encoded Ia molecule recognizes a similar immunodominant Ia recognition site (agretope) shared between Lol p I and Lol p II and/or III; in addition, Lol p I appears to contain unique Ia recognition site(s) not present in Lol p II and III. However, further epitope analyses are required to investigate these possibilities.

Invariance Signatures: Characterizing contours by their departures from invariance

OpenAIRE

Squire, David; Caelli, Terry M.

1997-01-01

In this paper, a new invariant feature of two-dimensional contours is reported: the Invariance Signature. The Invariance Signature is a measure of the degree to which a contour is invariant under a variety of transformations, derived from the theory of Lie transformation groups. It is shown that the Invariance Signature is itself invariant under shift, rotation and scaling of the contour. Since it is derived from local properties of the contour, it is well-suited to a neural network implement...

Affine invariants of convex polygons.

Science.gov (United States)

Flusser, Jan

2002-01-01

In this correspondence, we prove that the affine invariants, for image registration and object recognition, proposed recently by Yang and Cohen (see ibid., vol.8, no.7, p.934-46, July 1999) are algebraically dependent. We show how to select an independent and complete set of the invariants. The use of this new set leads to a significant reduction of the computing complexity without decreasing the discrimination power.

Novel topological invariants and anomalies

International Nuclear Information System (INIS)

Hirayama, M.; Sugimasa, N.

1987-01-01

It is shown that novel topological invariants are associated with a class of Dirac operators. Trace formulas which are similar to but different from Callias's formula are derived. Implications of these topological invariants to anomalies in quantum field theory are discussed. A new class of anomalies are calculated for two models: one is two dimensional and the other four dimensional

Thermodynamic controls on the kinetics of microbial low-pH Fe(II) oxidation.

Science.gov (United States)

Larson, Lance N; Sánchez-España, Javier; Kaley, Bradley; Sheng, Yizhi; Bibby, Kyle; Burgos, William D

2014-08-19

Acid mine drainage (AMD) is a major worldwide environmental threat to surface and groundwater quality. Microbial low-pH Fe(II) oxidation could be exploited for cost-effective AMD treatment; however, its use is limited because of uncertainties associated with its rate and ability to remove Fe from solution. We developed a thermodynamic-based framework to evaluate the kinetics of low-pH Fe(II) oxidation. We measured the kinetics of low-pH Fe(II) oxidation at five sites in the Appalachian Coal Basin in the US and three sites in the Iberian Pyrite Belt in Spain and found that the fastest rates of Fe(II) oxidation occurred at the sites with the lowest pH values. Thermodynamic calculations showed that the Gibbs free energy of Fe(II) oxidation (ΔG(oxidation)) was also most negative at the sites with the lowest pH values. We then conducted two series of microbial Fe(II) oxidation experiments in laboratory-scale chemostatic bioreactors operated through a series of pH values (2.1-4.2) and found the same relationships between Fe(II) oxidation kinetics, ΔG(oxidation), and pH. Conditions that favored the fastest rates of Fe(II) oxidation coincided with higher Fe(III) solubility. The solubility of Fe(III) minerals, thus plays an important role on Fe(II) oxidation kinetics. Methods to incorporate microbial low-pH Fe(II) oxidation into active and passive AMD treatment systems are discussed in the context of these findings. This study presents a simplified model that describes the relationship between free energy and microbial kinetics and should be broadly applicable to many biogeochemical systems.

Scale invariance of the η-deformed AdS5×S5 superstring, T-duality and modified type II equations

Directory of Open Access Journals (Sweden)

G. Arutyunov

2016-02-01

Full Text Available We consider the ABF background underlying the η-deformed AdS5×S5 sigma model. This background fails to satisfy the standard IIB supergravity equations which indicates that the corresponding sigma model is not Weyl invariant, i.e. does not define a critical string theory in the usual sense. We argue that the ABF background should still define a UV finite theory on a flat 2d world-sheet implying that the η-deformed model is scale invariant. This property follows from the formal relation via T-duality between the η-deformed model and the one defined by an exact type IIB supergravity solution that has 6 isometries albeit broken by a linear dilaton. We find that the ABF background satisfies candidate type IIB scale invariance conditions which for the R–R field strengths are of the second order in derivatives. Surprisingly, we also find that the ABF background obeys an interesting modification of the standard IIB supergravity equations that are first order in derivatives of R–R fields. These modified equations explicitly depend on Killing vectors of the ABF background and, although not universal, they imply the universal scale invariance conditions. Moreover, we show that it is precisely the non-isometric dilaton of the T-dual solution that leads, after T-duality, to modification of type II equations from their standard form. We conjecture that the modified equations should follow from κ-symmetry of the η-deformed model. All our observations apply also to η-deformations of AdS3×S3×T4and AdS2×S2×T6models.

p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-uncoupling in obesity.

Science.gov (United States)

Yu, Yi; Rajapakse, Angana G; Montani, Jean-Pierre; Yang, Zhihong; Ming, Xiu-Fen

2014-07-18

Endothelial nitric oxide synthase (eNOS)-uncoupling links obesity-associated insulin resistance and type-II diabetes to the increased incidence of cardiovascular disease. Studies have indicated that increased arginase is involved in eNOS-uncoupling through competing with the substrate L-arginine. Given that arginase-II (Arg-II) exerts some of its biological functions through crosstalk with signal transduction pathways, and that p38 mitogen-activated protein kinase (p38mapk) is involved in eNOS-uncoupling, we investigated here whether p38mapk is involved in Arg-II-mediated eNOS-uncoupling in a high fat diet (HFD)-induced obesity mouse model. Obesity was induced in wild type (WT) and Arg-II-deficient (Arg-II(-/-)) mice on C57BL/6 J background by high-fat diet (HFD, 55% fat) for 14 weeks starting from age of 7 weeks. The entire aortas were isolated and subjected to 1) immunoblotting analysis of the protein level of eNOS, Arg-II and p38mapk activation; 2) arginase activity assay; 3) endothelium-dependent and independent vasomotor responses; 4) en face staining of superoxide anion and NO production with Dihydroethidium and 4,5-Diaminofluorescein Diacetate, respectively, to assess eNOS-uncoupling. To evaluate the role of p38mapk, isolated aortas were treated with p38mapk inhibitor SB203580 (10 μmol/L, 1 h) prior to the analysis. In addition, the role of p38mapk in Arg-II-induced eNOS-uncoupling was investigated in cultured human endothelial cells overexpressing Arg-II in the absence or presence of shRNA against p38mapk. HFD enhanced Arg-II expression/activity and p38mapk activity, which was associated with eNOS-uncoupling as revealed by decreased NO and enhanced L-NAME-inhibitable superoxide in aortas of WT obese mice. In accordance, WT obese mice revealed decreased endothelium-dependent relaxations to acetylcholine despite of higher eNOS protein level, whereas Arg-II(-/-) obese mice were protected from HFD-induced eNOS-uncoupling and endothelial dysfunction, which

Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV

Directory of Open Access Journals (Sweden)

Rahul Sampath

2016-01-01

Full Text Available HIV cure is now the focus of intense research after Timothy Ray Brown (the Berlin patient set the precedent of being the first and only person cured. A major barrier to achieving this goal on a meaningful scale is an elimination of the latent reservoir, which is thought to comprise CD4-positive cells that harbor integrated, replication-competent HIV provirus. These cells do not express viral proteins, are indistinguishable from uninfected CD4 cells, and are thought to be responsible for HIV viral rebound–-that occurs within weeks of combination anti retroviral therapy (cART interruption. Modalities to engineer transcriptional stimulation (reactivation of this dormant integrated HIV provirus, leading to expression of cytotoxic viral proteins, are thought to be a specific way to eradicate the latently infected CD4 pool and are becoming increasingly relevant in the era of HIV cure. HIV protease is one such protein produced after HIV reactivation that cleaves procaspase-8 to generate a novel protein Casp8p41. Casp8p41 then binds to the BH3 domain of BAK, leading to BAK oligomerization, mitochondrial depolarization, and apoptosis. In central memory T cells (TCMs from HIV-infected patients, an elevated Bcl-2/procaspase-8 ratio was observed, and Casp8p41 binding to Bcl-2 was associated with a lack of reactivation-induced cell death. This was reversed by priming cells with a specific Bcl-2 antagonist prior to reactivation, resulting in increased cell death and decreased HIV DNA in a Casp8p41-dependent pathway. This review describes the biology, clinical relevance, and implications of Casp8p41 for a potential cure.

Notes on algebraic invariants for non-commutative dynamical systems

Energy Technology Data Exchange (ETDEWEB)

Longo, R [Rome Univ. (Italy). Istituto di Matematica

1979-11-01

We consider an algebraic invariant for non-commutative dynamical systems naturally arising as the spectrum of the modular operator associated to an invariant state, provided certain conditions of mixing type are present. This invariant turns out to be exactly the annihilator of the invariant T of Connes. Further comments are included, in particular on the type of certain algebras of local observables

The Pauli principle is sufficient to account for the broad structure in pp → π+d at the invariant mass of 2.41 GeV

International Nuclear Information System (INIS)

Svarc, A.

1992-01-01

The origin of the broad structure in the ratio of the differential cross section at O o and 30 o CMS scattering angle in the pp→π + d process at the invariant mass of 2.41 GeV, which has been extracted using the world collection of experimental data as input, has been analysed. The observed pattern can be generated by a combination of the Pauli principle restrictions upon the helicity amplitudes, combined with their individual and smooth energy behaviour. No assertions regarding additional dibaryon dynamics can be made without accounting for the observed effect. A toy model is presented solely as an illustration. (author)

Study on thermal, mechanical and adsorption properties of amine-functionalized MCM-41/PMMA and MCM-41/PS nanocomposites prepared by ultrasonic irradiation.

Science.gov (United States)

Mohammadnezhad, Gholamhossein; Abad, Saeed; Soltani, Roozbeh; Dinari, Mohammad

2017-11-01

In this study, two common industrial polymers, poly(methyl methacrylate) (PMMA) and polystyrene (PS), were incorporated into amine-functionalized MCM-41 mesoporous silica as reinforcement agents via an ultrasonic assisted method as a facile, fast, eco-friendly, and versatile synthetic tool. Amino functionalization of MCM-41 were performed by 3-aminopropyl triethoxysilane as a coupling agent and it is denoted as APTS-MCM-41. The obtained nanocomposites (NCs), APTS-MCM-41/PMMA and APTS-MCM-41/PS, were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning and transmission electron microscopies (SEM and TEM), and thermogravimetric analysis (TGA). Their mechanical properties were also probed via stress-strain curves and improved tensile properties were observed in the NCs relative to the neat polymers. Additionally, APTS-MCM-41/PMMA exhibited better mechanical properties than APTS-MCM-41/PS. Sorption studies were carried out on the two NCs and the effect of different process parameters, namely, pH, contact time, and initial Cd(II) concentration investigated in batch mode. Pseudo-second order and intraparticle diffusion models explain the Cd(II) kinetics more effectively for APTS-MCM-41/PMMA and APTS-MCM-41/PS, respectively. The adsorption isotherm data fitted well to Langmuir isotherm for both NCs and the maximum monolayer adsorption capacities were found to be 24.75mg/g and 10.42mg/g for APTS-MCM-41/PMMA and APTS-MCM-41/PS, respectively. The results demonstrate that the NCs show potential for use in adsorption of heavy metal ion such as Cd(II) from aqueous media. Copyright © 2017 Elsevier B.V. All rights reserved.

D-brane superpotentials and Ooguri-Vafa invariants of compact Calabi-Yau threefolds

Science.gov (United States)

Xu, Feng-Jun; Yang, Fu-Zhong

2015-04-01

We calculate the D-brane superpotentials for two compact Calabi-Yau manifolds X14(1,1,2,3,7) and X8(1,1,1,2,3) which are of non-Fermat type in the type II string theory. By constructing the open mirror symmetry, we also compute the Ooguri-Vafa invariants, which are related to the open Gromov-Witten invariants. Supported by NSFC (11075204, 11475178)

Measurement invariance versus selection invariance: Is fair selection possible?

NARCIS (Netherlands)

Borsboom, D.; Romeijn, J.W.; Wicherts, J.M.

2008-01-01

This article shows that measurement invariance (defined in terms of an invariant measurement model in different groups) is generally inconsistent with selection invariance (defined in terms of equal sensitivity and specificity across groups). In particular, when a unidimensional measurement

Measurement invariance versus selection invariance : Is fair selection possible?

NARCIS (Netherlands)

Borsboom, Denny; Romeijn, Jan-Willem; Wicherts, Jelte M.

This article shows that measurement invariance (defined in terms of an invariant measurement model in different groups) is generally inconsistent with selection invariance (defined in terms of equal sensitivity and specificity across groups). In particular, when a unidimensional measurement

Association of Cross Linked C-Telopeptide II Collagen and Hyaluronic Acid with Knee Osteoarthritis Severity

Directory of Open Access Journals (Sweden)

John Butar Butar

2013-12-01

Full Text Available BACKGROUND: This study was carried out to investigate the association of Cross Linked C-Telopeptide Type I & II Collagen (CTX-I and II and hyaluronic acid (HA with knee osteoarthritis (OA severity. METHODS: Sixty menopause women with primary knee OA were enrolled in this study during their visits to the Outpatient Department. Patients with knee pain during weight bearing, active or passive range of motion, or tenderness with Kellgren-Lawrence (KL grade of more than I were included. Patients with injury, inflammatory and metabolic diseases were excluded. Patients were put in a 10-hour fasting prior to withdrawal of morning blood samples for examinations of HA, CTX-I, interleukin 1 beta (IL-1β, and high sensitivity C reactive protein (hs-CRP level. Second void morning urine specimens were taken for CTXII assessment. HA, CTX-I and II levels were measured by enzyme-linked immunosorbent assay. RESULTS: Sixty menopausal female patients were included in this study, 35 with KL grade II, 17 grade III, and 8 grade IV. Means of CTX-II were significantly different between subjects KL grade IV and III (p=0.021. Correlation of KL grade was significant with CTX-II (p=0.001, r=0.412 and HA (p=0.0411, r=0.269. KL grades were not significantly associated with CTX-I (p=0.8364, r=-0.0272; IL-1β (p=0.5773, r=0.0853 and hs-CRP (p=0.2625, r=0.1470. CONCLUSIONS: CTX-II and HA were associated with severity of knee OA, suggesting that CTX-II and HA can be used as marker for knee OA severity. KEYWORDS: CTX-II, hyaluronic acid, otestoarthritis, knee.

Towards a constructive approach of a gauge invariant, massive P(PHI)2 theory

International Nuclear Information System (INIS)

Schrader, R.

1978-01-01

As part of a possible constructive approach to a gauge invariant P(PHI) 2 theory, we consider massive, scalar, polynomially selfcoupled fields PHI in a fixed external Yang-Mills potential A in two dimensional euclidean space. For a large class of A's we show that the corresponding euclidean Green's functions for fields PHI have a lower mass gap for weak coupling which is uniform in A. The result is obtained by adapting the Glimm-Jaffe-Spencer cluster expansion to the present situation through Kato's inequality, which reflects the diamagnetic effect of the Yang-Mills potential. A dicussion of the corresponding gauge covariance is included. (orig.) [de

Do time-invariant confounders explain away the association between job stress and workers' mental health? Evidence from Japanese occupational panel data.

Science.gov (United States)

Oshio, Takashi; Tsutsumi, Akizumi; Inoue, Akiomi

2015-02-01

It is well known that job stress is negatively related to workers' mental health, but most recent studies have not controlled for unobserved time-invariant confounders. In the current study, we attempted to validate previous observations on the association between job stress and workers' mental health, by removing the effects of unobserved time-invariant confounders. We used data from three to four waves of an occupational Japanese cohort survey, focusing on 31,382 observations of 9741 individuals who participated in at least two consecutive waves. We estimated mean-centered fixed effects models to explain psychological distress in terms of the Kessler 6 (K6) scores (range: 0-24) by eight job stress indicators related to the job demands-control, effort-reward imbalance, and organizational injustice models. Mean-centered fixed effects models reduced the magnitude of the association between jobs stress and K6 scores to 44.8-54.2% of those observed from pooled ordinary least squares. However, the association remained highly significant even after controlling for unobserved time-invariant confounders for all job stress indicators. In addition, alternatively specified models showed the robustness of the results. In all, we concluded that the validity of major job stress models, which link job stress and workers' mental health, was robust, although unobserved time-invariant confounders led to an overestimation of the association. Copyright © 2014 Elsevier Ltd. All rights reserved.

The N-Terminal Flanking Region of the Invariant Chain Peptide Augments the Immunogenicity of a Cryptic “Self” Epitope from a Tumor-Associated Antigen

NARCIS (Netherlands)

Hess, A.D.; Thoburn, C.; Chen, W.; Miura, Y.; Wall, E. van der

2001-01-01

The N-terminal flanking region of the invariant chain peptide termed CLIP appears to have superagonistic properties interacting with the T cell receptor and the MHC class II molecule at or near the binding site for the bacterial superantigen Staphylococcal enterotoxin B (SEB). The present studies

IgE and IgG cross-reactivity among Lol p I and Lol p II/III. Identification of the C-termini of Lol p I, II, and III as cross-reactive structures.

Science.gov (United States)

van Ree, R; van Leeuwen, W A; van den Berg, M; Weller, H H; Aalberse, R C

1994-04-01

In this study, the homologous C-termini of Lol p I, Lol p II, and Lol p III were shown to contain cross-reactive B-cell epitopes. This was demonstrated by inhibition studies with purified Lol p I, II, and III and synthetic peptides of their C-termini. It was ruled out that the observed cross-reactivity was caused by cross-contamination of the purified allergens. Both human IgE and IgG bound to the C-terminus of Lol p I. These antibodies were cross-reactive with Lol p II and, more specifically, with its C-terminus. Within a small panel of allergic patients, no cross-reactivity with Lol p III was found. A hyperimmune polyclonal rabbit antiserum against Lol p I also recognized the Lol p I C-terminus. As for human antibodies, cross-reactivity with Lol p II and its C-terminus was demonstrated. Cross-reactivity with Lol p III was demonstrated with C-terminal peptides, but not with native Lol p III. A polyclonal rabbit antiserum against Lol p II bound to the C-terminal peptides of both Lol p II and III. This binding was inhibited with Lol p I, confirming that cross-reactive structures exist not only on the C-termini of Lol p II and Lol p I, but also of Lol p III and Lol p I. The existence of cross-reactivity between Lol p I and Lol p II and III possibly contributes to the frequently observed cosensitization for these allergens in grass-pollen-allergic patients.

The pMSSM Interpretation of LHC Results Using Rernormalization Group Invariants

Energy Technology Data Exchange (ETDEWEB)

Carena, Marcela [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Lykken, Joseph [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Sekmen, Sezen [CERN, Geneva (Switzerland); Shah, Nausheen R. [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Wagner, Carlos E.M. [Enrico Fermi Institute, Univ. of Chicago, IL (United States)

2012-10-01

The LHC has started to constrain supersymmetry-breaking parameters by setting bounds on possible colored particles at the weak scale. Moreover, constraints from Higgs physics, flavor physics, the anomalous magnetic moment of the muon, as well as from searches at LEP and the Tevatron have set additional bounds on these parameters. Renormalization Group Invariants (RGIs) provide a very useful way of representing the allowed parameter space by making direct connection with the values of these parameters at the messenger scale. Using a general approach, based on the pMSSM parametrization of the soft supersymmetry-breaking parameters, we analyze the current experimental constraints to determine the probability distributions for the RGIs. As examples of their application, we use these distributions to analyze the question of Gaugino Mass Unification and to probabilistically determine the parameters of General and Minimal Gauge Mediation with arbitrary Higgs mass parameters at the Messenger Scale.

The pMSSM Interpretation of LHC Results Using Rernormalization Group Invariants

CERN Document Server

Carena, Marcela; Sekmen, Sezen; Shah, Nausheen R; Wagner, Carlos E M

2012-01-01

The LHC has started to constrain supersymmetry-breaking parameters by setting bounds on possible colored particles at the weak scale. Moreover, constraints from Higgs physics, flavor physics, the anomalous magnetic moment of the muon, as well as from searches at LEP and the Tevatron have set additional bounds on these parameters. Renormalization Group Invariants (RGIs) provide a very useful way of representing the allowed parameter space by making direct connection with the values of these parameters at the messenger scale. Using a general approach, based on the pMSSM parametrization of the soft supersymmetry-breaking parameters, we analyze the current experimental constraints to determine the probability distributions for the RGIs. As examples of their application, we use these distributions to analyze the question of Gaugino Mass Unification and to probabilistically determine the parameters of General and Minimal Gauge Mediation with arbitrary Higgs mass parameters at the Messenger Scale.

Vector analyzing power and cross section for the reactions 40Ar(d(pol),p)41Ar and 40Ar(d(pol),t)39Ar

International Nuclear Information System (INIS)

Sen, S.; Darden, S.E.; Yoh, W.A.; Berners, E.D.

1975-01-01

Angular distributions of vector analyzing power and cross section for the reactions 40 Ar(d,p) 41 Ar and 40 Ar(d,t) 39 Ar have been measured at an incident deuteron energy of 14.83 MeV. The bound-state data in the (d,p) reaction and the (d,t) data are compared to DWBA calculations. The data for the neutron-unbound states are analyzed in the framework of the DWBA using (i) a form factor for weakly bound neutron and (ii) a resonance form factor, following the approach of Vincent and Fortune. The j-dependence of the (d,p) vector analyzing power permits definite spin-parity assignments to be made for 19 neutron-bound and 4 neutron unbound states in 41 Ar with excitation energy up to 6.57 MeV. Tentative Jsup(π) assignments have been made for 3 states. The l-value for the 5.62 MeV states has been determined. Data for the observed unbound states are found to be equally well reproduced by the type (i) calculations as by the type (ii) calculations. The (d,t) vector cnalyzing power data show definite J-dependence although not as strongly as in the (d,p) reaction. For relatively weakly excited states a pre-knowledge of the l-value of the transition is desirable for an unambiguous spin assignment. In general, the J-dependence in the (d,t) vector analyzing power can be utilized for definitive Jsup(π) assignments. On this basis, Jsub(π) values have been assigned for seven states in 39 Ar with excitation energies up to 4.47MeV excitation. Possible spin values for three other states are suggested. Spectroscopic factors fo the states in 41 Ar and 39 Ar have been extracted and are in fair agreement with those obtained by other workers. (Auth.)

Association of the p53 codon 72 polymorphism to gastric cancer risk in a high risk population of Costa Rica

International Nuclear Information System (INIS)

Alpizar-Alpizar, Warner; Sierra, Rafaela; Cuenca, Patricia; Une, Clas; Mena, Fernando; Perez-Perez, Guillermo Ignacio

2005-01-01

Gastric cancer is the second most common cancer associated death cause worldwide. Several factors have been associated with higher risk to develop gastric cancer, among them genetic predisposition. The p53 gene has a polymorphism located at codon 72, which has been associated with higher risk of several types of cancer, including gastric cancer. The aim of this study was to determine the association of p53, codon 72 polymorphism, with the risk of gastric cancer and pre-malignant lesions in a high-risk population from Costa Rica. The genotyping was carried out by PCR-RFLP in a sample of 58 gastric cancer patients, 99 control persons and 41 individuals classified as group I and II, according to the Japanese histological classification. No association was found for p53, codon 72 polymorphism with neither the risk of gastric cancer nor the risk of less severe gastric lesions in the studied sample. Based on this study and taking into account other studies carried out with p53, codon 72 polymorphism, the role of this polymorphism in the development of gastric cancer remains unclear. De novo mutations on p53 gene produced during neoplastic development of this disease might play a greater role than germinal polymorphisms of this same gene. Other polymorphic genes have been associated with higher risk to develop gastric cancer. (author) [es

Recombinant allergen Lol p II: expression, purification and characterization.

Science.gov (United States)

Tamborini, E; Brandazza, A; De Lalla, C; Musco, G; Siccardi, A G; Arosio, P; Sidoli, A

1995-05-01

Pollen from perennial rye grass (Lolium perenne) is a major cause of type I allergies worldwide. It contains complex mixtures of proteins, among which Lol p II is a major allergen. Previously, we have reported the cloning and sequencing of Lol p II and its expression in fusion with the heavy chain of human ferritin as carrier polypeptide (Sidoli et al., 1993, J. biol. Chem. 268, 21819-21825). Here, we describe the expression, purification and characterization of a recombinant Lol p II overproduced as a non-fusion protein in the periplasm of E. coli. The recombinant allergen was expressed in high yields and was easily purified in milligram amounts. It competed with the natural Lol p II for binding to specific IgE, and it induced allergic responses in skin prick tests, indicating to be immunologically analogous to the natural protein. Biochemical analyses indicate that recombinant Lol p II is a highly stable and soluble monomeric molecule which behaves like a small globular protein.

Admissible invariant distributions on reductive

CERN Document Server

Harish-Chandra; Paul J Sally, Jr

1999-01-01

Harish-Chandra presented these lectures on admissible invariant distributions for p-adic groups at the Institute for Advanced Study in the early 1970s. He published a short sketch of this material as his famous "Queen's Notes". This book, which was prepared and edited by DeBacker and Sally, presents a faithful rendering of Harish-Chandra's original lecture notes. The main purpose of Harish-Chandra's lectures was to show that the character of an irreducible admissible representation of a connected reductive p-adic group G is represented by a locally summable function on G. A key ingredient in this proof is the study of the Fourier transforms of distributions on \\mathfrak g, the Lie algebra of G. In particular, Harish-Chandra shows that if the support of a G-invariant distribution on \\mathfrak g is compactly generated, then its Fourier transform has an asymptotic expansion about any semisimple point of \\mathfrak g. Harish-Chandra's remarkable theorem on the local summability of characters for p-adic groups was ...

Invariant functionals in higher-spin theory

Directory of Open Access Journals (Sweden)

M.A. Vasiliev

2017-03-01

Full Text Available A new construction for gauge invariant functionals in the nonlinear higher-spin theory is proposed. Being supported by differential forms closed by virtue of the higher-spin equations, invariant functionals are associated with central elements of the higher-spin algebra. In the on-shell AdS4 higher-spin theory we identify a four-form conjectured to represent the generating functional for 3d boundary correlators and a two-form argued to support charges for black hole solutions. Two actions for 3d boundary conformal higher-spin theory are associated with the two parity-invariant higher-spin models in AdS4. The peculiarity of the spinorial formulation of the on-shell AdS3 higher-spin theory, where the invariant functional is supported by a two-form, is conjectured to be related to the holomorphic factorization at the boundary. The nonlinear part of the star-product function F⁎(B(x in the higher-spin equations is argued to lead to divergencies in the boundary limit representing singularities at coinciding boundary space–time points of the factors of B(x, which can be regularized by the point splitting. An interpretation of the RG flow in terms of proposed construction is briefly discussed.

Hybrid generative-discriminative approach to age-invariant face recognition

Science.gov (United States)

Sajid, Muhammad; Shafique, Tamoor

2018-03-01

Age-invariant face recognition is still a challenging research problem due to the complex aging process involving types of facial tissues, skin, fat, muscles, and bones. Most of the related studies that have addressed the aging problem are focused on generative representation (aging simulation) or discriminative representation (feature-based approaches). Designing an appropriate hybrid approach taking into account both the generative and discriminative representations for age-invariant face recognition remains an open problem. We perform a hybrid matching to achieve robustness to aging variations. This approach automatically segments the eyes, nose-bridge, and mouth regions, which are relatively less sensitive to aging variations compared with the rest of the facial regions that are age-sensitive. The aging variations of age-sensitive facial parts are compensated using a demographic-aware generative model based on a bridged denoising autoencoder. The age-insensitive facial parts are represented by pixel average vector-based local binary patterns. Deep convolutional neural networks are used to extract relative features of age-sensitive and age-insensitive facial parts. Finally, the feature vectors of age-sensitive and age-insensitive facial parts are fused to achieve the recognition results. Extensive experimental results on morphological face database II (MORPH II), face and gesture recognition network (FG-NET), and Verification Subset of cross-age celebrity dataset (CACD-VS) demonstrate the effectiveness of the proposed method for age-invariant face recognition well.

Power suppressed operators and gauge invariance in soft-collinear effective theory

International Nuclear Information System (INIS)

Bauer, Christian W.; Pirjol, Dan; Stewart, Iain W.

2003-01-01

The form of collinear gauge invariance for power suppressed operators in the soft-collinear effective theory (SCET) is discussed. Using a field redefinition we show that it is possible to make any power suppressed ultrasoft-collinear operators invariant under the original leading order gauge transformations. Our manipulations avoid gauge fixing. The Lagrangians to O(λ 2 ) are given in terms of these new fields. We then give a simple procedure for constructing power suppressed soft-collinear operators in SCET II by using an intermediate theory SCET I

Computational invariant theory

CERN Document Server

Derksen, Harm

2015-01-01

This book is about the computational aspects of invariant theory. Of central interest is the question how the invariant ring of a given group action can be calculated. Algorithms for this purpose form the main pillars around which the book is built. There are two introductory chapters, one on Gröbner basis methods and one on the basic concepts of invariant theory, which prepare the ground for the algorithms. Then algorithms for computing invariants of finite and reductive groups are discussed. Particular emphasis lies on interrelations between structural properties of invariant rings and computational methods. Finally, the book contains a chapter on applications of invariant theory, covering fields as disparate as graph theory, coding theory, dynamical systems, and computer vision. The book is intended for postgraduate students as well as researchers in geometry, computer algebra, and, of course, invariant theory. The text is enriched with numerous explicit examples which illustrate the theory and should be ...

(p,3He) reactions on 1p shell nuclei at 41 and 45 MeV

International Nuclear Information System (INIS)

Rapp, V.

1982-01-01

In the present thesis the (p, 3 He) reactions on target nuclei of the 1p shell were studied. The measurements were performed at the isochronous cyclotron of the KFA Juelich. Angular distribution at 41 and 45 MeV to residual nuclear states in 7 Li, 8 Be, 9 Be, 10 B, 11 B, 12 C, 13 C, and 14 N. were evaluated. (orig.) [de

SA-4-1BBL costimulation inhibits conversion of conventional CD4+ T cells into CD4+ FoxP3+ T regulatory cells by production of IFN-γ.

Directory of Open Access Journals (Sweden)

Shravan Madireddi

Full Text Available Tumors convert conventional CD4(+ T cells into induced CD4(+CD25(+FoxP3(+ T regulatory (iTreg cells that serve as an effective means of immune evasion. Therefore, the blockade of conventional CD4(+ T cell conversion into iTreg cells represents an attractive target for improving the efficacy of various immunotherapeutic approaches. Using a novel form of 4-1BBL molecule, SA-4-1BBL, we previously demonstrated that costimulation via 4-1BB receptor renders both CD4(+and CD8(+ T effector (Teff cells refractory to inhibition by Treg cells and increased intratumoral Teff/Treg cell ratio that correlated with therapeutic efficacy in various preclinical tumor models. Building on these studies, we herein show for the first time, to our knowledge, that signaling through 4-1BB inhibits antigen- and TGF-β-driven conversion of naïve CD4(+FoxP3(- T cells into iTreg cells via stimulation of IFN-γ production by CD4(+FoxP3(- T cells. Importantly, treatment with SA-4-1BBL blocked the conversion of CD4(+FoxP3(- T cells into Treg cells by EG.7 tumors. Taken together with our previous studies, these results show that 4-1BB signaling negatively modulate Treg cells by two distinct mechanisms: i inhibiting the conversion of CD4(+FoxP3(- T cells into iTreg cells and ii endowing Teff cells refractory to inhibition by Treg cells. Given the dominant role of Treg cells in tumor immune evasion mechanisms, 4-1BB signaling represents an attractive target for favorably tipping the Teff:Treg balance toward Teff cells with important implications for cancer immunotherapy.

Small Lesion Size Is Associated with Sleep-Related Epilepsy in Focal Cortical Dysplasia Type II

Directory of Open Access Journals (Sweden)

Bo Jin

2018-02-01

Full Text Available ObjectiveTo investigate the neuroimaging and clinical features associated with sleep-related epilepsy (SRE in patients with focal cortical dysplasia (FCD type II.MethodsPatients with histopathologically proven FCD type II were included from three epilepsy centers. SRE was defined according to the video EEG findings and seizure history. Cortical surface reconstruction and volume calculation were performed using FreeSurfer. The lesions were manually delineated on T1 volumetric MRI using the ITK-SNAP software. The lesion volumes were normalized by the intracranial volume of each patient. The lesions were classified as small or large by placing a threshold based on quantitative (whether the lesion was detected on MRI report and qualitative (volume criteria.ResultsA total of 77 consecutive patients were included. Of them, 36 had SRE and 41 had non-SRE. An earlier age of epilepsy onset, high seizure frequency, regional interictal EEG findings, and favorable surgical outcome were characteristic in both groups. Small lesions were defined as those having a volume <3,217 mm3. In total, 60.9% of the patients with SRE (25/41 had small FCD lesion, which was significantly higher than the non-SRE group (9/34, 26.5%, p = 0.005. Small lesion size was the only predictor significantly associated with SRE in the overall type II group by multivariate analyses (p = 0.016. Although the proportion of patients who had frontal FCD and SRE was higher than non-frontal FCD (54.5 vs. 27.3%, p = 0.043, the relationship between SRE and lesion location was not confirmed by multivariate analysis. Thalamic volume and seizure semiology were not statistically different between the SRE and non-SRE group. The significant association between lesion size and SRE was reproducible in type IIb and IIa subgroups.SignificanceSRE is common in patients with FCD type II. Small FCD type II lesions are significantly associated with SRE. Although our findings cannot be applied to

Invariant submanifold flows

Energy Technology Data Exchange (ETDEWEB)

Olver, Peter J [School of Mathematics, University of Minnesota, Minneapolis, MN 55455 (United States)], E-mail: olver@math.umn.edu

2008-08-29

Given a Lie group acting on a manifold, our aim is to analyze the evolution of differential invariants under invariant submanifold flows. The constructions are based on the equivariant method of moving frames and the induced invariant variational bicomplex. Applications to integrable soliton dynamics, and to the evolution of differential invariant signatures, used in equivalence problems and object recognition and symmetry detection in images, are discussed.

Quantum tunneling, adiabatic invariance and black hole spectroscopy

Science.gov (United States)

Li, Guo-Ping; Pu, Jin; Jiang, Qing-Quan; Zu, Xiao-Tao

2017-05-01

In the tunneling framework, one of us, Jiang, together with Han has studied the black hole spectroscopy via adiabatic invariance, where the adiabatic invariant quantity has been intriguingly obtained by investigating the oscillating velocity of the black hole horizon. In this paper, we attempt to improve Jiang-Han's proposal in two ways. Firstly, we once again examine the fact that, in different types (Schwarzschild and Painlevé) of coordinates as well as in different gravity frames, the adiabatic invariant I_adia = \\oint p_i dq_i introduced by Jiang and Han is canonically invariant. Secondly, we attempt to confirm Jiang-Han's proposal reasonably in more general gravity frames (including Einstein's gravity, EGB gravity and HL gravity). Concurrently, for improving this proposal, we interestingly find in more general gravity theories that the entropy of the black hole is an adiabatic invariant action variable, but the horizon area is only an adiabatic invariant. In this sense, we emphasize the concept that the quantum of the black hole entropy is more natural than that of the horizon area.

A renormalization group invariant line and an infrared attractive top-Higgs mass relation

International Nuclear Information System (INIS)

Schrempp, B.; Schrempp, F.

1992-10-01

The renormalization group equations (RGE's) of the Standard Model at one loop in terms of the gauge couplings g 1,2,3, the top Yukawa coupling g t and the scalar self coupling λ are reexamined. For g 1,2 = 0, the general solution of the RGE's is obtained analytically in terms of an interesting special solution for the ratio λ/g 2 t as function of the ratio g 2 t /g 2 3 which i) represents an RG invariant line which is strongly infrared attractive ii) interpolates all known quasi-fixed points and iii) is finite for large g 2 t /g 2 3 (ultraviolet limit). All essential features survive for g 1,2 ≠ 0. The invariant line translates into an infrared attractive top-Higgs mass relation, which e.g. associates to the top masses m t = 130/145/200 GeV the Higgs masses m H ≅ 68-90/103-115/207 GeV, respectively. (orig.)

Invariant subspaces in some function spaces on symmetric spaces. II

International Nuclear Information System (INIS)

Platonov, S S

1998-01-01

Let G be a semisimple connected Lie group with finite centre, K a maximal compact subgroup of G, and M=G/K a Riemannian symmetric space of non-compact type. We study the problem of describing the structure of closed linear subspaces in various function spaces on M that are invariant under the quasiregular representation of the group G. We consider the case when M is a symplectic symmetric space of rank 1

p13 from group II baculoviruses is a killing-associated gene

Directory of Open Access Journals (Sweden)

Yipeng Qi

2012-12-01

Full Text Available p13 gene was first described in Leucania separata multinuclearpolyhedrosis virus (Ls-p13 several years ago, but the functionof P13 protein has not been experimentally investigated todate. In this article, we indicated that the expression of p13from Heliothis armigera single nucleocapsid nucleopolyhedrovirus(Ha-p13 was regulated by both early and late promoter.Luciferase assay demonstrated that the activity of Ha-p13promoter with hr4 enhancer was more than 100 times inheterologous Sf9 cells than that in nature host Hz-AM1 cells.Both Ls-P13 and Ha-P13 are transmembrane proteins. Confocalmicroscopic analysis showed that both mainly located in thecytoplasm membrane at 48 h. Results of RNA interferenceindicated that Ha-p13 was a killing-associated gene for hostinsects H. armigera. The AcMNPV acquired the mentionedkilling activity and markedly accelerate the killing rate whenexpressing Ls-p13. In conclusion, p13 is a killing associatedgene in both homologous and heterologous nucleopolyhedrovirus.

Invariance identities associated with finite gauge transformations and the uniqueness of the equations of motion of a particle in a classical gauge field

International Nuclear Information System (INIS)

Rund, H.

1984-01-01

A certain class of geometric objects is considered against the background of a classical gauge field associated with an arbitrary structural Lie group. It is shown that the necessary and sufficient conditions for the invariance of the given objects under a finite gauge transformation are embodied in a set of three relations involving the derivatives of their components. As a special case these so-called invariance identities indicate that there cannot exist a gauge-invariant Lagrangian that depends on the gauge potentials, the interaction parameters, and the 4-velocity components of a test particle. However, the requirement that the equations of motion that result from such a lagrangian be gauge-invariant, uniquely determines the structure of these equations. (author)

Permutation invariant polynomial neural network approach to fitting potential energy surfaces. II. Four-atom systems

Energy Technology Data Exchange (ETDEWEB)

Li, Jun; Jiang, Bin; Guo, Hua, E-mail: hguo@unm.edu [Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico 87131 (United States)

2013-11-28

A rigorous, general, and simple method to fit global and permutation invariant potential energy surfaces (PESs) using neural networks (NNs) is discussed. This so-called permutation invariant polynomial neural network (PIP-NN) method imposes permutation symmetry by using in its input a set of symmetry functions based on PIPs. For systems with more than three atoms, it is shown that the number of symmetry functions in the input vector needs to be larger than the number of internal coordinates in order to include both the primary and secondary invariant polynomials. This PIP-NN method is successfully demonstrated in three atom-triatomic reactive systems, resulting in full-dimensional global PESs with average errors on the order of meV. These PESs are used in full-dimensional quantum dynamical calculations.

Gauge invariance of the Rayleigh--Schroedinger time-independent perturbation theory

International Nuclear Information System (INIS)

Yang, K.H.

1977-08-01

It is shown that the Rayleigh-Schroedinger time-independent perturbation theory is gauge invariant when the operator concerned is the particle's instantaneous energy operator H/sub B/ = (1/2m)[vector p - (e/c) vector A] 2 + eV 0 . More explicitly, it is shown that the energy perturbation corrections of each individual order of every state is gauge invariant. When the vector potential is curlless, the energy corrections of all orders are shown to vanish identically regardless of the explicit form of the vector potential. The relation between causality and gauge invariance is investigated. It is shown that gauge invariance guarantees conformity with causality and violation of gauge invariance implies violation of causality

Galileo-invariant theory of low energy pion-nucleus scattering. II

International Nuclear Information System (INIS)

Mach, R.

1983-01-01

Two classes of Galileo-invariant optical models are constructed for pion elastic scattering by nuclei. The former, the two-body model, was obtained assuming that the pion-bound nucleon dynamics is determined by the pion-nucleon kinetic energy. In deriving the latter model, the (A+1)-body dynamics was taken into account. The technique of effective nucleon momenta maintains the nonlocal propagation of the pion-target nucleon subsystem through the nucleus in contrast with the standard static approximation. (author)

TYPE II-P SUPERNOVAE FROM THE SDSS-II SUPERNOVA SURVEY AND THE STANDARDIZED CANDLE METHOD

International Nuclear Information System (INIS)

D'Andrea, Chris B.; Sako, Masao; Dilday, Benjamin; Jha, Saurabh; Frieman, Joshua A.; Kessler, Richard; Holtzman, Jon; Konishi, Kohki; Yasuda, Naoki; Schneider, D. P.; Sollerman, Jesper; Wheeler, J. Craig; Cinabro, David; Nichol, Robert C.; Lampeitl, Hubert; Smith, Mathew; Atlee, David W.; Bassett, Bruce; Castander, Francisco J.; Goobar, Ariel

2010-01-01

We apply the Standardized Candle Method (SCM) for Type II Plateau supernovae (SNe II-P), which relates the velocity of the ejecta of a SN to its luminosity during the plateau, to 15 SNe II-P discovered over the three season run of the Sloan Digital Sky Survey-II Supernova Survey. The redshifts of these SNe-0.027 0.01) as all of the current literature on the SCM combined. We find that the SDSS SNe have a very small intrinsic I-band dispersion (0.22 mag), which can be attributed to selection effects. When the SCM is applied to the combined SDSS-plus-literature set of SNe II-P, the dispersion increases to 0.29 mag, larger than the scatter for either set of SNe separately. We show that the standardization cannot be further improved by eliminating SNe with positive plateau decline rates, as proposed in Poznanski et al. We thoroughly examine all potential systematic effects and conclude that for the SCM to be useful for cosmology, the methods currently used to determine the Fe II velocity at day 50 must be improved, and spectral templates able to encompass the intrinsic variations of Type II-P SNe will be needed.

Constraining the Volatile Composition and Coma Photochemistry in Jupiter Family Comet 41P/Tuttle-Giacobini-Kresak with High Resolution IR and Optical Spectroscopy

Science.gov (United States)

McKay, Adam; DiSanti, Michael; Cochran, Anita; Dello Russo, Neil; Bonev, Boncho; Vervack, Ronald; Gibb, Erika; Roth, Nathan; Kawakita, Hideyo

2018-01-01

Over the past 20 years optical and IR spectroscopy of cometary comae has expanded our understanding both of cometary volatile composition and coma photochemistry. However, these observations tend to be biased towards Nearly Isotropic Comets (NIC'S) from the Oort Cloud, rather than the generally fainter and less active Jupiter Family Comets (JFC's) that are thought to originate from the Scattered Disk. However, early 2017 provided a rare opportunity to study several JFC's. We present preliminary results from IR and optical spectroscopy of JFC 41P/Tuttle-Giacobini-Kresak obtained during its 2017 apparition. IR spectra were obtained with the NIRSPEC instrument on Keck II and the new iSHELL spectrograph on NASA IRTF. High spectral resolution optical spectra were obtained with the Tull Coude spectrograph on the 2.7-meter Harlan J. Smith Telescope at McDonald Observatory. We will discuss mixing ratios of HCN, NH3, C2H6, C2H2, H2CO, and CH3OH compared to H2O and compare these to previous observations of comets. Preliminary results from the NIRSPEC observations indicate that 41P has typical C2H2 and HCN abundances compared to other JFC's, while the C2H6 abundance is similar to that of NIC's, but is enriched compared to other JFC's. H2CO appears to be heavily depleted in 41P. Analysis of the iSHELL spectra is underway and we will include results from these observations, which complement those from NIRSPEC and extend the scope or our compositional study by measuring additional molecules. We will also present abundances for CN, C2, NH2, C3, and CH obtained from the optical spectra and discuss the implications for the coma photochemistry.This work is supported by the NASA Postdoctoral Program, administered by the Universities Space Research Association, with additional funding from the NSF and NASA PAST.

Local and nonlocal advected invariants and helicities in magnetohydrodynamics and gas dynamics: II. Noether's theorems and Casimirs

International Nuclear Information System (INIS)

Webb, G M; Dasgupta, B; McKenzie, J F; Hu, Q; Zank, G P

2014-01-01

Conservation laws in ideal gas dynamics and magnetohydrodynamics (MHD) associated with fluid relabeling symmetries are derived using Noether's first and second theorems. Lie dragged invariants are discussed in terms of the MHD Casimirs. A nonlocal conservation law for fluid helicity applicable for a non-barotropic fluid involving Clebsch variables is derived using Noether's theorem, in conjunction with a fluid relabeling symmetry and a gauge transformation. A nonlocal cross helicity conservation law involving Clebsch potentials, and the MHD energy conservation law are derived by the same method. An Euler–Poincaré variational approach is also used to derive conservation laws associated with fluid relabeling symmetries using Noether's second theorem. (paper)

Quantum tunneling, adiabatic invariance and black hole spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Li, Guo-Ping; Zu, Xiao-Tao [University of Electronic Science and Technology of China, School of Physical Electronics, Chengdu (China); Pu, Jin [University of Electronic Science and Technology of China, School of Physical Electronics, Chengdu (China); China West Normal University, College of Physics and Space Science, Nanchong (China); Jiang, Qing-Quan [China West Normal University, College of Physics and Space Science, Nanchong (China)

2017-05-15

In the tunneling framework, one of us, Jiang, together with Han has studied the black hole spectroscopy via adiabatic invariance, where the adiabatic invariant quantity has been intriguingly obtained by investigating the oscillating velocity of the black hole horizon. In this paper, we attempt to improve Jiang-Han's proposal in two ways. Firstly, we once again examine the fact that, in different types (Schwarzschild and Painleve) of coordinates as well as in different gravity frames, the adiabatic invariant I{sub adia} = circular integral p{sub i}dq{sub i} introduced by Jiang and Han is canonically invariant. Secondly, we attempt to confirm Jiang-Han's proposal reasonably in more general gravity frames (including Einstein's gravity, EGB gravity and HL gravity). Concurrently, for improving this proposal, we interestingly find in more general gravity theories that the entropy of the black hole is an adiabatic invariant action variable, but the horizon area is only an adiabatic invariant. In this sense, we emphasize the concept that the quantum of the black hole entropy is more natural than that of the horizon area. (orig.)

A class of P,T-invariant topological phases of interacting electrons

International Nuclear Information System (INIS)

Freedman, Michael; Nayak, Chetan; Shtengel, Kirill; Walker, Kevin; Wang Zhenghan

2004-01-01

We describe a class of parity- and time-reversal-invariant topological states of matter which can arise in correlated electron systems in 2+1-dimensions. These states are characterized by particle-like excitations exhibiting exotic braiding statistics. P and T invariance are maintained by a 'doubling' of the low-energy degrees of freedom which occurs naturally without doubling the underlying microscopic degrees of freedom. The simplest examples have been the subject of considerable interest as proposed mechanisms for high-T c superconductivity. One is the 'doubled' version of the chiral spin liquid. The chiral spin liquid gives rise to anyon superconductivity at finite doping and the corresponding field theory is U(1) Chern-Simons theory at coupling constant m=2. The 'doubled' theory is two copies of this theory, one with m=2 the other with m=-2. The second example corresponds to Z 2 gauge theory, which describes a scenario for spin-charge separation. Our main concern, with an eye towards applications to quantum computation, are richer models which support non-Abelian statistics. All of these models, richer or poorer, lie in a tightly organized discrete family indexed by the Baraha numbers, 2cos(π/(k+2)), for positive integer k. The physical inference is that a material manifesting the Z 2 gauge theory or a doubled chiral spin liquid might be easily altered to one capable of universal quantum computation. These phases of matter have a field-theoretic description in terms of gauge theories which, in their infrared limits, are topological field theories. We motivate these gauge theories using a parton model or slave-fermion construction and show how they can be solved exactly. The structure of the resulting Hilbert spaces can be understood in purely combinatorial terms. The highly constrained nature of this combinatorial construction, phrased in the language of the topology of curves on surfaces, lays the groundwork for a strategy for constructing microscopic

Synthesis and structural characterization of nickel(II), cobalt(II), Zinc(II), manganese(II), cadmium(II) and uranium(VI) complexes of α-oximinoacetoacet-o/p-anisidide thiosemicarbazone

International Nuclear Information System (INIS)

Patel, P.S.; Patel, M.M.; Ray, R.M.

1993-01-01

A few metal complexes of α-oximinoacetoacet-o/p-anisidide thiosemicarbazones (OAOATS)/(OAPATS) with Ni(II), Co(II), Zn(II), Mn(II), Hg(II), Cd(II) and UO 2 (II) have been prepared and characterized by elemental analyses, conductivity, differential scanning calorimetry study, thermogravimetric analyses and infrared and electronic spectral measurements in conjunction with magnetic susceptibility measurements at room temperature. They have also been tested for their antimicrobial activities. (author). 24 refs., 2 tabs

Glenoid fossa position in Class II malocclusion associated with mandibular retrusion.

Science.gov (United States)

Giuntini, Veronica; De Toffol, Laura; Franchi, Lorenzo; Baccetti, Tiziano

2008-09-01

To assess the position of the glenoid fossa in subjects with Class II malocclusion associated with mandibular retrusion and normal mandibular size in the mixed dentition. A sample of 30 subjects (16 male, 14 female), age 9 years +/- 6 months, with skeletal and dental Class II malocclusion associated with mandibular retrusion, normal skeletal vertical relationships, and normal mandibular dimensions, was compared with a matched group of 37 subjects (18 male, 19 female) with skeletal and dental Class I relationships. The comparisons between the Class II group and the control group on the cephalometric measures for the assessment of glenoid fossa position were performed by means of a nonparametric test for independent samples (Mann-Whitney U-test, P < .05). Subjects with Class II malocclusion presented with a significantly more distal position of the glenoid fossa, when compared with the control group as measured by means of three parameters (GF-S on FH, GF-Ptm on FH, and GF-FMN). A posteriorly displaced glenoid fossa is a possible diagnostic feature of Class II malocclusion associated with mandibular retrusion. An effective cephalometric measurement to evaluate glenoid fossa position is the distance from the glenoid fossa to the frontomaxillonasal suture (GF-FMN).

Hydroconversion of methyl laurate on bifunctional Ni2P/AlMCM-41 catalyst prepared via in situ phosphorization using triphenylphosphine

Science.gov (United States)

Zhao, Sha; Zhang, Zhena; Zhu, Kongying; Chen, Jixiang

2017-05-01

A series of Ni2P/AlMCM-41-x bifunctional catalysts with different Si/Al ratios (x) were synthesized by in situ phosphorization of Ni/AlMCM-41-x with triphenylphosphine (nominal Ni/P ratio of 0.75) at 300 °C on a fixed-bed reactor. For comparison, NiP/AlMCM-41-5-TPR was also prepared by the TPR method from the supported nickel phosphate with the Ni/P ratio of 1.0, during which metallic Ni rather than Ni2P formed. TEM images show that Ni and Ni2P particles uniformly distributed in Ni2P/AlMCM-41-x and NiP/AlMCM-41-5-TPR. The Ni2P/AlMCM-41-x acidity increased with decreasing the Si/Al ratio. In the hydroconversion of methyl laurate, the conversions were close to 100% on all catalysts at 360 °C, 3.0 MPa, methyl laurate WHSV of 2 h-1 and H2/methyl laurate ratio of 25. As to Ni2P/AlMCM-41-x, with decreasing the Si/Al ratio, the total selectivity to C11 and C12 hydrocarbons decreased, while the total selectivity to isoundecane and isododecane (Si-C11+i-C12) firstly increased and then decreased. Ni2P/AlMCM-41-5 gave the largest Si-C11+i-C12 of 43.2%. While NiP/AlMCM-41-5-TPR gave higher Si-C11+i-C12 than Ni2P/AlMCM-41-5, it was more active for the undesired Csbnd C bond cleavage and methanation. We propose that the in-situ phosphorization adopted here is a promising approach to preparing Ni2P-based bifunctional catalysts.

pH-dependence of the specific binding of Cu(II) and Zn(II) ions to the amyloid-β peptide

International Nuclear Information System (INIS)

Ghalebani, Leila; Wahlström, Anna; Danielsson, Jens; Wärmländer, Sebastian K.T.S.; Gräslund, Astrid

2012-01-01

Highlights: ► Cu(II) and Zn(II) display pH-dependent binding to the Aβ(1–40) peptide. ► At pH 7.4 both metal ions display residue-specific binding to the Aβ peptide. ► At pH 5.5 the binding specificity is lost for Zn(II). ► Differential Cu(II) and Zn(II) binding may help explain metal-induced AD toxicity. -- Abstract: Metal ions like Cu(II) and Zn(II) are accumulated in Alzheimer’s disease amyloid plaques. The amyloid-β (Aβ) peptide involved in the disease interacts with these metal ions at neutral pH via ligands provided by the N-terminal histidines and the N-terminus. The present study uses high-resolution NMR spectroscopy to monitor the residue-specific interactions of Cu(II) and Zn(II) with 15 N- and 13 C, 15 N-labeled Aβ(1–40) peptides at varying pH levels. At pH 7.4 both ions bind to the specific ligands, competing with one another. At pH 5.5 Cu(II) retains its specific histidine ligands, while Zn(II) seems to lack residue-specific interactions. The low pH mimics acidosis which is linked to inflammatory processes in vivo. The results suggest that the cell toxic effects of redox active Cu(II) binding to Aβ may be reversed by the protective activity of non-redox active Zn(II) binding to the same major binding site under non-acidic conditions. Under acidic conditions, the protective effect of Zn(II) may be decreased or changed, since Zn(II) is less able to compete with Cu(II) for the specific binding site on the Aβ peptide under these conditions.

Field transformations, collective coordinates and BRST invariance

International Nuclear Information System (INIS)

Alfaro, J.; Damgaard, P.H.

1989-12-01

A very large class of general field transformations can be viewed as a field theory generalization of the method of collective coordinates. The introduction of new variables induces a gauge invariance in the transformed theory, and the freedom left in gauge fixing this new invariance can be used to find equivalent formulations of the same theory. First the Batalin-Fradkin-Vilkovisky formalism is applied to the Hamiltonian formulation of physical systems that can be described in terms of collective coordinates. We then show how this type of collective coordinate scheme can be generalized to field transformations, and discuss the War Identities of the associated BRST invariance. For Yang-Mills theory a connection to topological field theory and the background field method is explained in detail. In general the resulting BRST invariance we find hidden in any quantum field theory can be viewed as a consequence of our freedom in choosing a basis of coordinates φ(χ) in the action S[φ]. (orig.)

Hydroconversion of methyl laurate on bifunctional Ni{sub 2}P/AlMCM-41 catalyst prepared via in situ phosphorization using triphenylphosphine

Energy Technology Data Exchange (ETDEWEB)

Zhao, Sha; Zhang, Zhena [Tianjin Key Laboratory of Applied Catalysis Science and Technology, Department of Catalysis Science and Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072 (China); Zhu, Kongying, E-mail: ausky@tju.edu.cn [Analysis and Measurement Center, Tianjin University, Tianjin 300072 (China); Chen, Jixiang, E-mail: jxchen@tju.edu.cn [Tianjin Key Laboratory of Applied Catalysis Science and Technology, Department of Catalysis Science and Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072 (China)

2017-05-15

Highlights: • Bifunctional Ni{sub 2}P/AlMCM-41 was prepared by in situ phosphorization at 300 °C. • There were similar Ni{sub 2}P particle sizes in Ni{sub 2}P/AlMCM-41 with different Si/Al ratios. • The acid amount of Ni{sub 2}P/AlMCM-41 increased with decreasing the Si/Al ratio. • Ni{sub 2}P/AlMCM-41 with the Si/Al ratio of 5 had the highest activity for isomerization. • Ni{sub 2}P/AlMCM-41 had very low activity for methanation and C−C bond hydrogenolysis. - Abstract: A series of Ni{sub 2}P/AlMCM-41-x bifunctional catalysts with different Si/Al ratios (x) were synthesized by in situ phosphorization of Ni/AlMCM-41-x with triphenylphosphine (nominal Ni/P ratio of 0.75) at 300 °C on a fixed-bed reactor. For comparison, NiP/AlMCM-41-5-TPR was also prepared by the TPR method from the supported nickel phosphate with the Ni/P ratio of 1.0, during which metallic Ni rather than Ni{sub 2}P formed. TEM images show that Ni and Ni{sub 2}P particles uniformly distributed in Ni{sub 2}P/AlMCM-41-x and NiP/AlMCM-41-5-TPR. The Ni{sub 2}P/AlMCM-41-x acidity increased with decreasing the Si/Al ratio. In the hydroconversion of methyl laurate, the conversions were close to 100% on all catalysts at 360 °C, 3.0 MPa, methyl laurate WHSV of 2 h{sup −1} and H{sub 2}/methyl laurate ratio of 25. As to Ni{sub 2}P/AlMCM-41-x, with decreasing the Si/Al ratio, the total selectivity to C11 and C12 hydrocarbons decreased, while the total selectivity to isoundecane and isododecane (S{sub i-C11+i-C12}) firstly increased and then decreased. Ni{sub 2}P/AlMCM-41-5 gave the largest S{sub i-C11+i-C12} of 43.2%. While NiP/AlMCM-41-5-TPR gave higher S{sub i-C11+i-C12} than Ni{sub 2}P/AlMCM-41-5, it was more active for the undesired C−C bond cleavage and methanation. We propose that the in-situ phosphorization adopted here is a promising approach to preparing Ni{sub 2}P-based bifunctional catalysts.

Translationally invariant and non-translationally invariant empirical effective interactions

International Nuclear Information System (INIS)

Golin, M.; Zamick, L.

1975-01-01

In this work empirical deficiencies of the core-renormalized realistic effective interactions are examined and simple corrective potentials are sought. The inability of the current realistic interactions to account for the energies of isobaric analog states is noted, likewise they are unable to reproduce the changes in the single-particle energies, as one goes from one closed shell to another. It is noted that the Schiffer interaction gives better results for these gross properties and this is attributed to a combination of several facts. First, to the inclusion of long range terms in the Schiffer potential, then to the presence of relative p-state terms (l=1), in addition to the usual relative s-state terms (l=0). The strange shape of the above interaction is further attributed to the fact that it is translationally invariant whereas the theory of core-polarization yields non-translationally invariant potentials. Consequently, as a correction to the monopole deficiencies of the realistic interactions the term Vsub(mon)=ar 2 (1)r 2 (2)+r 2 (1)+β[r 4 (1)r 2 (2)r 4 (2) ] is proposed. (Auth.)

Invariant structures in gauge theories and confinement

International Nuclear Information System (INIS)

Prokhorov, L.V.; Shabanov, S.V.

1991-01-01

The problem of finding all gauge invariants is considered in connection with the problem of confinement. Polylocal gauge tensors are introduced and studied. It is shown (both in physical and pure geometrical approaches) that the path-ordered exponent is the only fundamental bilocal gauge tensor, which means that any irreducible polylocal gauge tensor is built of P-exponents and local tensors (matter fields). The simplest invariant structures in electrodynamics, chromodynamics and a theory with the gauge group SU(2) are considered separately. 23 refs.; 2 figs

Invariant and semi-invariant probabilistic normed spaces

Energy Technology Data Exchange (ETDEWEB)

Ghaemi, M.B. [School of Mathematics Iran, University of Science and Technology, Narmak, Tehran (Iran, Islamic Republic of)], E-mail: mghaemi@iust.ac.ir; Lafuerza-Guillen, B. [Departamento de Estadistica y Matematica Aplicada, Universidad de Almeria, Almeria E-04120 (Spain)], E-mail: blafuerz@ual.es; Saiedinezhad, S. [School of Mathematics Iran, University of Science and Technology, Narmak, Tehran (Iran, Islamic Republic of)], E-mail: ssaiedinezhad@yahoo.com

2009-10-15

Probabilistic metric spaces were introduced by Karl Menger. Alsina, Schweizer and Sklar gave a general definition of probabilistic normed space based on the definition of Menger . We introduce the concept of semi-invariance among the PN spaces. In this paper we will find a sufficient condition for some PN spaces to be semi-invariant. We will show that PN spaces are normal spaces. Urysohn's lemma, and Tietze extension theorem for them are proved.

DNA polymorphism of HLA class II genes in pauciarticular juvenile rheumatoid arthritis

DEFF Research Database (Denmark)

Morling, N; Friis, J; Fugger, L

1991-01-01

associated with the following HLA class II genes were increased in PJRA when compared to normal controls: DRB1*08 (DRw8) (35.2% vs 10.3%, RR = 4.6, p less than 10(-3), DRB3*01/02/03 (DRw52) (76.3% vs 48.1%, RR 3.5, p less than 10(-3)), DQA1*0401 (41.0% vs 7.4%, RR = 7.9, p less than 10(-3)), DQA1*0501 (55...... of DNA fragments associated with the following HLA class II genes were decreased in PJRA although not statistically significantly so after 'correction' of p values: DRB1*04 (14.8% vs 40.2%, RR = 0.27; p less than 10(-3)), DRB1*07 (0% vs 25.9%, RR = 0.04, p less than 10(-3)), DRB4*0101 (DRw53) (25.9% vs...... 53.6%, RR = 0.31, p less than 10(-3)), DQA1*0102 (11.6% vs 36.0%, RR = 0.25, p less than 10(-4)), and DQA1*0201 (2.6% vs 34.2%, RR = 0.05, p less than 10(-2)).(ABSTRACT TRUNCATED AT 250 WORDS)...

Association of tRNA methyltransferase NSUN2/IGF-II molecular signature with ovarian cancer survival.

Science.gov (United States)

Yang, Jia-Cheng; Risch, Eric; Zhang, Meiqin; Huang, Chan; Huang, Huatian; Lu, Lingeng

2017-09-01

To investigate the association between NSUN2/IGF-II signature and ovarian cancer survival. Using a publicly accessible dataset of RNA sequencing and clinical follow-up data, we performed Classification and Regression Tree and survival analyses. Patients with NSUN2 high IGF-II low had significantly superior overall and disease progression-free survival, followed by NSUN2 low IGF-II low , NSUN2 high IGF-II high and NSUN2 low IGF-II high (p IGF-II signature with the risks of death and relapse remained significant in multivariate Cox regression models. Random-effects meta-analyses show the upregulated NSUN2 and IGF-II expression in ovarian cancer versus normal tissues. The NSUN2/IGF-II signature associates with heterogeneous outcome and may have clinical implications in managing ovarian cancer.

Rotationally invariant correlation filtering

International Nuclear Information System (INIS)

Schils, G.F.; Sweeney, D.W.

1985-01-01

A method is presented for analyzing and designing optical correlation filters that have tailored rotational invariance properties. The concept of a correlation of an image with a rotation of itself is introduced. A unified theory of rotation-invariant filtering is then formulated. The unified approach describes matched filters (with no rotation invariance) and circular-harmonic filters (with full rotation invariance) as special cases. The continuum of intermediate cases is described in terms of a cyclic convolution operation over angle. The angular filtering approach allows an exact choice for the continuous trade-off between loss of the correlation energy (or specificity regarding the image) and the amount of rotational invariance desired

On local invariants of singular symplectic forms

Science.gov (United States)

Domitrz, Wojciech

2017-04-01

We find a complete set of local invariants of singular symplectic forms with the structurally stable Martinet hypersurface on a 2 n-dimensional manifold. In the C-analytic category this set consists of the Martinet hypersurface Σ2, the restriction of the singular symplectic form ω to TΣ2 and the kernel of ω n - 1 at the point p ∈Σ2. In the R-analytic and smooth categories this set contains one more invariant: the canonical orientation of Σ2. We find the conditions to determine the kernel of ω n - 1 at p by the other invariants. In dimension 4 we find sufficient conditions to determine the equivalence class of a singular symplectic form-germ with the structurally smooth Martinet hypersurface by the Martinet hypersurface and the restriction of the singular symplectic form to it. We also study the singular symplectic forms with singular Martinet hypersurfaces. We prove that the equivalence class of such singular symplectic form-germ is determined by the Martinet hypersurface, the canonical orientation of its regular part and the restriction of the singular symplectic form to its regular part if the Martinet hypersurface is a quasi-homogeneous hypersurface with an isolated singularity.

IgE and IgG cross-reactivity among Lol p I and Lol p II/III. Identification of the C-termini of Lol p I, II, and III as cross-reactive structures

NARCIS (Netherlands)

van Ree, R.; van Leeuwen, W. A.; van den Berg, M.; Weller, H. H.; Aalberse, R. C.

1994-01-01

In this study, the homologous C-termini of Lol p I, Lol p II, and Lol p III were shown to contain cross-reactive B-cell epitopes. This was demonstrated by inhibition studies with purified Lol p I, II, and III and synthetic peptides of their C-termini. It was ruled out that the observed

APACHE II as an indicator of ventilator-associated pneumonia (VAP.

Directory of Open Access Journals (Sweden)

Kelser de Souza Kock

2015-01-01

Full Text Available Background and objectives: strategies for risk stratification in severe pathologies are extremely important. The aim of this study was to analyze the accuracy of the APACHE II score as an indicator of Ventilator-Associated Pneumonia (VAP in ICU patient sat Hospital Nossa Senhora da Conceição (HNSC Tubarão-SC. Methods: It was conducted a prospective cohort study with 120 patients admitted between March and August 2013, being held APACHE II in the first 24 hours of mechanical ventilation (MV. Patients were followed until the following gout comes: discharge or death. It was also analyzed the cause of ICU admission, age, gender, days of mechanical ventilation, length of ICU and outcome. Results: The incidence of VAP was 31.8% (38/120. Two variables showed a relative riskin the development of VAP, APACHE II above average (RR = 1,62; IC 95% 1,03-2,55 and males (RR = 1,56; IC 95 % 1,18-2,08. The duration of mechanical ventilation (days above average18.4± 14.9(p =0.001, ICU stay (days above average 20.4± 15.3(p =0.003 presented the development of VAP. The accuracy of APACHE II in predicting VAP score >23, showed a sensitivity of 84% and specificity of 33%. Inrelation to death, two variables showed relative risk, age above average (RR=2.08; 95% CI =1.34 to 3.23 and ICU stay above average (RR=2.05; CI 95 =1.28 to 3.28%. Conclusion: The APACHE II score above or equal 23 might to indicate the risk of VAP. Keywords: Pneumonia, Ventilator-Associated, Intensive Care Units, APACHE. Prognosis

Small RNAs were involved in homozygous state-associated silencing of a marker gene (Neomycin phosphotransferase II: nptII) in transgenic tomato plants.

Science.gov (United States)

Deng, Lei; Pan, Yu; Chen, Xuqing; Chen, Guoping; Hu, Zongli

2013-07-01

Homozygous state-associated co-suppression is not a very common phenomenon. In our experiments, two transgenic plants 3A29 and 1195A were constructed by being transformed with the constructs pBIN-353A and pBIN119A containing nptII gene as a marker respectively. The homozygous progeny from these two independent transgenic lines 3A29 and 1195A, displayed kanamycin-sensitivity and produced a short main root without any lateral roots as untransformed control (wild-type) seedlings when germinated on kanamycin media. For the seedlings derived from putative hemizygous plants, the percentage of the seedlings showing normal growth on kanamycin media was about 50% and lower than the expected percentage (75%). Southern analysis of the genomic DNA confirmed that the homozygous and hemizygous plants derived from the same lines contained the same multiple nptII transgenes, which were located on the same site of chromosome. Northern analysis suggested that the marker nptII gene was expressed in the primary and the hemizygous transformants, but it was silenced in the homozygous transgenic plants. Further Northern analysis indicated that antisense and sense small nptII-derived RNAs were present in the transgenic plants and the blotting signal of nptII-derived small RNA was much higher in the homozygous transgenic plants than that of hemizygous transgenic plants. Additionally, read-through transcripts from the TRAMP gene to the nptII gene were detected. These results suggest that the read-through transcripts may be involved in homozygous state-associated silencing of the nptII transgene in transgenic tomato plants and a certain threshold level of the nptII-derived small RNAs is required for the homozygous state-associated co-suppression of the nptII transgene. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Are the invariance principles really truly Lorentz covariant?

International Nuclear Information System (INIS)

Arunasalam, V.

1994-02-01

It is shown that some sections of the invariance (or symmetry) principles such as the space reversal symmetry (or parity P) and time reversal symmetry T (of elementary particle and condensed matter physics, etc.) are not really truly Lorentz covariant. Indeed, I find that the Dirac-Wigner sense of Lorentz invariance is not in full compliance with the Einstein-Minkowski reguirements of the Lorentz covariance of all physical laws (i.e., the world space Mach principle)

On asymptotics and resurgent structures of enumerative Gromov-Witten invariants

International Nuclear Information System (INIS)

Couso-Santamaria, Ricardo; Schiappa, Ricardo; Geneve Univ.; Vaz, Ricardo; DESY Hamburg

2016-05-01

Making use of large-order techniques in asymptotics and resurgent analysis, this work addresses the growth of enumerative Gromov-Witten invariants - in their dependence upon genus and degree of the embedded curve - for several different threefold Calabi-Yau toric-varieties. In particular, while the leading asymptotics of these invariants at large genus or at large degree is exponential, at combined large genus and degree it turns out to be factorial. This factorial growth has a resurgent nature, originating via mirror symmetry from the resurgent-transseries description of the B-model free energy. This implies the existence of nonperturbative sectors controlling the asymptotics of the Gromov-Witten invariants, which could themselves have an enumerative-geometry interpretation. The examples addressed include: the resolved conifold; the local surfaces local P 2 and local P 1 x P 1 ; the local curves and Hurwitz theory; and the compact quintic. All examples suggest very rich interplays between resurgent asymptotics and enumerative problems in algebraic geometry.

On asymptotics and resurgent structures of enumerative Gromov-Witten invariants

Energy Technology Data Exchange (ETDEWEB)

Couso-Santamaria, Ricardo [Lisboa Univ. (Portugal). Inst. Superior Tecnico (IST); Schiappa, Ricardo [Lisboa Univ. (Portugal). Inst. Superior Tecnico (IST); Geneve Univ. (Switzerland). Dept. de Physique Theoretique et Section de Mathematiques; Vaz, Ricardo [Lisboa Univ. (Portugal). Inst. Superior Tecnico (IST); DESY Hamburg (Germany). Theory Group

2016-05-15

Making use of large-order techniques in asymptotics and resurgent analysis, this work addresses the growth of enumerative Gromov-Witten invariants - in their dependence upon genus and degree of the embedded curve - for several different threefold Calabi-Yau toric-varieties. In particular, while the leading asymptotics of these invariants at large genus or at large degree is exponential, at combined large genus and degree it turns out to be factorial. This factorial growth has a resurgent nature, originating via mirror symmetry from the resurgent-transseries description of the B-model free energy. This implies the existence of nonperturbative sectors controlling the asymptotics of the Gromov-Witten invariants, which could themselves have an enumerative-geometry interpretation. The examples addressed include: the resolved conifold; the local surfaces local P{sup 2} and local P{sup 1} x P{sup 1}; the local curves and Hurwitz theory; and the compact quintic. All examples suggest very rich interplays between resurgent asymptotics and enumerative problems in algebraic geometry.

American tertiary clinic-referred bipolar II disorder versus bipolar I disorder associated with hastened depressive recurrence.

Science.gov (United States)

Dell'Osso, Bernardo; Shah, Saloni; Do, Dennis; Yuen, Laura D; Hooshmand, Farnaz; Wang, Po W; Miller, Shefali; Ketter, Terence A

2017-12-01

Bipolar disorder (BD) is a chronic, frequently comorbid condition characterized by high rates of mood episode recurrence and suicidality. Little is known about prospective longitudinal characterization of BD type II (BD II) versus type I (BD I) in relation to time to depressive recurrence and recovery from major depressive episode. We therefore assessed times to depressive recurrence/recovery in tertiary clinic-referred BD II versus I patients. Outpatients referred to Stanford BD Clinic during 2000-2011 were assessed with Systematic Treatment Enhancement Program for BD (STEP-BD) Affective Disorders Evaluation and with Clinical Monitoring Form during up to 2 years of naturalistic treatment. Prevalence and clinical correlates of bipolar subtype in recovered (euthymic ≥8 weeks) and depressed patients were assessed. Kaplan-Meier analyses assessed the relationships between bipolar subtype and longitudinal depressive severity, and Cox proportional hazard analyses assessed the potential mediators. BD II versus BD I was less common among 105 recovered (39.0 vs. 61.0%, p = 0.03) and more common among 153 depressed (61.4 vs. 38.6%, p = 0.006) patients. Among recovered patients, BD II was associated with 6/25 (24.0%) baseline unfavorable illness characteristics/mood symptoms/psychotropics and hastened depressive recurrence (p = 0.015). Among depressed patients, BD II was associated with 8/25 (33.0%) baseline unfavorable illness characteristics/mood symptoms/psychotropics, but only non-significantly associated with delayed depressive recovery. BD II versus BD I was significantly associated with current depression and hastened depressive recurrence, but only non-significantly associated with delayed depressive recovery. Research on bipolar subtype relationships with depressive recurrence/recovery is warranted to enhance clinical management of BD patients.

Properties of invariant modelling and invariant glueing of vector fields

International Nuclear Information System (INIS)

Petukhov, V.R.

1987-01-01

Invariant modelling and invariant glueing of both continuous (rates and accelerations) and descrete vector fields, gradient and divergence cases are considered. The following appendices are discussed: vector fields in crystals, crystal disclinations, topological charges and their fields

Hypoadiponectinemia in obese subjects with type II diabetes: A close association with central obesity indices

Directory of Open Access Journals (Sweden)

Ghorban Mohammadzadeh

2011-01-01

Full Text Available Background: Adiponectin is an adipocyte secreted protein with important biological functions Hypoadiponectinemia is associated with obesity, insulin resistance, and type II diabetes This study aimed to evaluate serum adiponectin level in obese subjects with type II diabetes and its correlation with metabolic parameters Methods: This cross-sectional study was performed on 40 obese subjects with type II diabetes and 40 non-diabetic obese control subjects Fasting lipid profile was measured by the enzymatic methods The NycoCard HbA1c protocol was used to measure HbAlc The Serum adiponectin, insulin and glucose levels were measured using an enzyme immunoassay and glucose oxidase methods respectively Results: Type II diabetes was associated with hypoadiponectinemia, in both men and women Serum adiponectin level in non-diabetic subjects (6.44 ± 2.47 μg/ml was significantly higher than diabetics (4.55 ± 1.88 μg/ml Furthermore, serum adiponectin concentration in females was significantly higher than males in non-diabetics (7.18 ± 2.68 vs 5.61 ± 0.57 and diabetic groups (5.18 ± 2.08 vs 3.99 ± 1.5 There was a negative and significant correlation between serum adiponectin level with waist (r = -0.451, p = 0.003, waist to hip ratio (r = -0.404, p = 0.01 and BMI (r = - 0.322, p = 0.042 and a positive correlation with HDL (r = 0.337, p = 0.034 in non-diabetic group In diabetic group, there was only found a negative correlation between adiponectin and waist size (r = -0.317, p = 0.046 Conclusions: Obesity and type II diabetes are associated with low serum adiponectin concentration

Yeast hexokinase. A fluorescence temperature-jump study of the kinetics of the binding of glucose to the monomer forms of hexokinases P-I and P-II.

Science.gov (United States)

Hoggett, J G; Kellett, G L

1976-09-15

The binding of glucose to the monomeric forms of hexokinases P-I and P-II in Tris and phosphate buffers at pH 8.0 in the presence of 1 mol l-1 KCl has been studied using the fluorescence temperature-jump technique. For both isozymes only one relaxation time was observed; values of tau-1 increased linearly with increasing concentration of free reacting partners. The apparent second-order rate constant for association was about 2 X 10(6) 1 mol-1 s-1 for both isozymes; the differences in the stabilities of the complexes with P-I and P-II are entirely attributable to the fact that glucose dissociates more slowly from its complex with P-I than P-II (approximately 300 s-1 and 1100 s-1 respectively). Although the kinetic data are compatible with a single-step mechanism for glucose binding the association rate constant was much lower than that expected for a diffusion-limited rate of encounter. Other mechanisms for describing an induced-fit are discussed. It is shown that the data are incompatible with a slow 'prior-isomerization' pathway of substrate binding, but are consistent with a 'substrate-guided' pathway involving isomerization of the enzyme-substrate complex.

Mechanism insight of pollutant degradation and bromate inhibition by Fe-Cu-MCM-41 catalyzed ozonation.

Science.gov (United States)

Chen, Weirui; Li, Xukai; Tang, Yiming; Zhou, Jialu; Wu, Dan; Wu, Yin; Li, Laisheng

2018-03-15

A flexible catalyst, Fe-Cu-MCM-41, was employed to enhance diclofenac (DCF) mineralization and inhibit bromate formation in catalytic ozonation process. Greater TOC removal was achieved in Fe-Cu-MCM-41/O 3 process (78%) than those in Fe-MCM-41/O 3 (65%), Cu-MCM-41/O 3 (73%) and sole ozonation (42%). But it was interesting that both Cu-MCM-41/O 3 and Fe-MCM-41/O 3 achieved 93% bromate inhibition efficiency, only 71% inhibition efficiency was observed in Fe-Cu-MCM-41/O 3 . Influence of pH, TBA/NaHSO 3 and detection of by-products were conducted to explore the mechanism. By Pyridine adsorption-IR and XPS, a relationship was found among activity of catalysts, Lewis acid sites and electron transfer effect between Fe (II/III) and Cu (I/II). Fe-Cu-MCM-41 promoted ozone decomposition to generate OH, which accounted for enhanced DCF mineralization. The consumption of aqueous O 3 also suppressed the oxidative of Br - and HBrO/Br - . More HBrO/BrO - accumulated in catalytic ozonation process and less bromate generated. Bromate formation in Fe-Cu-MCM-41/O 3 process was sensitive with pH value, the acidic condition was not favor for bromate formation. Both DCF mineralization and bromate inhibition were influenced by surface reaction. Moreover, Fe-Cu-MCM-41 showed excellent catalytic performance in suppressing the accumulation of carboxylic acid, especially for oxalic acid. Nearly no oxalic acid was detected during Fe-Cu-MCM-41/O 3 process. Copyright © 2017 Elsevier B.V. All rights reserved.

Msn2p/Msn4p act as a key transcriptional activator of yeast cytoplasmic thiol peroxidase II.

Science.gov (United States)

Hong, Seung-Keun; Cha, Mee-Kyung; Choi, Yong-Soo; Kim, Won-Cheol; Kim, Il-Han

2002-04-05

We observed that the transcription of Saccharomyces cerevisiae cytoplasmic thiol peroxidase type II (cTPx II) (YDR453C) is regulated in response to various stresses (e.g. oxidative stress, carbon starvation, and heat-shock). It has been suggested that both transcription-activating proteins, Yap1p and Skn7p, regulate the transcription of cTPx II upon exposure to oxidative stress. However, a dramatic loss of transcriptional response to various stresses in yeast mutant strains lacking both Msn2p and Msn4p suggests that the transcription factors act as a principal transcriptional activator. In addition to two Yap1p response elements (YREs), TTACTAA and TTAGTAA, the presence of two stress response elements (STREs) (CCCCT) in the upstream sequence of cTPx II also suggests that Msn2p/Msn4p could control stress-induced expression of cTPx II. Analysis of the transcriptional activity of site-directed mutagenesis of the putative STREs (STRE1 and STRE2) and YREs (TRE1 and YRE2) in terms of the activity of a lacZ reporter gene under control of the cTPx II promoter indicates that STRE2 acts as a principal binding element essential for transactivation of the cTPx II promoter. The transcriptional activity of the cTPx II promoter was exponentially increased after postdiauxic growth. The transcriptional activity of the cTPx II promoter is greatly increased by rapamycin. Deletion of Tor1, Tor2, Ras1, and Ras2 resulted in a considerable induction when compared with their parent strains, suggesting that the transcription of cTPx II is under negative control of the Ras/cAMP and target of rapamycin signaling pathways. Taken together, these results suggest that cTPx II is a target of Msn2p/Msn4p transcription factors under negative control of the Ras-protein kinase A and target of rapamycin signaling pathways. Furthermore, the accumulation of cTPx II upon exposure to oxidative stress and during the postdiauxic shift suggests an important antioxidant role in stationary phase yeast cells.

A portable data acquisition system on J.I.P.P. T-II ICRF experiment

International Nuclear Information System (INIS)

Hidekuma, S.

1982-03-01

This system has been developed for the data acquisition in the J.I.P.P. T-II ICRF experiment. It is composed of the LSI-11/2(56KB), a dual floppy disk drive, CAMAC modules, a graphic display and an interface module to the HITAC 10-II system. The operating system is RT-11. This system has functions of the data acquisition through A-D converters (max.32ch), the transfer of the data to the HITAC 10-II system and the preservation of them in its floppy disk. Furthermore, a user can easily develop his application programs with this system. The operating procedures of this system are described. (author)

Remarks on the E-invariant and the Casson invariant

International Nuclear Information System (INIS)

Seade, J.

1991-08-01

In this work a framed manifold means a pair (M,F) consisting of a closed C ∞ , stably parallelizable manifold M, together with a trivialization F of its stable tangent bundle. The purpose of this work is to understand and determine in higher dimensions the invariant h(M,F) appearing in connection with the Adams e-invariants. 28 refs

Biological low pH Mn(II) oxidation in a manganese deposit influenced by metal-rich groundwater

Science.gov (United States)

Bohu, Tsing; Akob, Denise M.; Abratis, Michael; Lazar, Cassandre S.; Küsel, Kirsten

2016-01-01

The mechanisms, key organisms, and geochemical significance of biological low-pH Mn(II) oxidation are largely unexplored. Here, we investigated the structure of indigenous Mn(II)-oxidizing microbial communities in a secondary subsurface Mn oxide deposit influenced by acidic (pH 4.8) metal-rich groundwater in a former uranium mining area. Microbial diversity was highest in the Mn deposit compared to the adjacent soil layers and included the majority of known Mn(II)-oxidizing bacteria (MOB) and two genera of known Mn(II)-oxidizing fungi (MOF). Electron X-ray microanalysis showed that romanechite [(Ba,H2O)2(Mn4+,Mn3+)5O10] was conspicuously enriched in the deposit. Canonical correspondence analysis revealed that certain fungal, bacterial, and archaeal groups were firmly associated with the autochthonous Mn oxides. Eight MOB within the Proteobacteria, Actinobacteria, and Bacteroidetes and one MOF strain belonging to Ascomycota were isolated at pH 5.5 or 7.2 from the acidic Mn deposit. Soil-groundwater microcosms demonstrated 2.5-fold-faster Mn(II) depletion in the Mn deposit than adjacent soil layers. No depletion was observed in the abiotic controls, suggesting that biological contribution is the main driver for Mn(II) oxidation at low pH. The composition and species specificity of the native low-pH Mn(II) oxidizers were highly adapted to in situ conditions, and these organisms may play a central role in the fundamental biogeochemical processes (e.g., metal natural attenuation) occurring in the acidic, oligotrophic, and metalliferous subsoil ecosystems.

Invariants of generalized Lie algebras

International Nuclear Information System (INIS)

Agrawala, V.K.

1981-01-01

Invariants and invariant multilinear forms are defined for generalized Lie algebras with arbitrary grading and commutation factor. Explicit constructions of invariants and vector operators are given by contracting invariant forms with basic elements of the generalized Lie algebra. The use of the matrix of a linear map between graded vector spaces is emphasized. With the help of this matrix, the concept of graded trace of a linear operator is introduced, which is a rich source of multilinear forms of degree zero. To illustrate the use of invariants, a characteristic identity similar to that of Green is derived and a few Racah coefficients are evaluated in terms of invariants

Field-theory representation of gauge-gravity symmetry-protected topological invariants, group cohomology, and beyond.

Science.gov (United States)

Wang, Juven C; Gu, Zheng-Cheng; Wen, Xiao-Gang

2015-01-23

The challenge of identifying symmetry-protected topological states (SPTs) is due to their lack of symmetry-breaking order parameters and intrinsic topological orders. For this reason, it is impossible to formulate SPTs under Ginzburg-Landau theory or probe SPTs via fractionalized bulk excitations and topology-dependent ground state degeneracy. However, the partition functions from path integrals with various symmetry twists are universal SPT invariants, fully characterizing SPTs. In this work, we use gauge fields to represent those symmetry twists in closed spacetimes of any dimensionality and arbitrary topology. This allows us to express the SPT invariants in terms of continuum field theory. We show that SPT invariants of pure gauge actions describe the SPTs predicted by group cohomology, while the mixed gauge-gravity actions describe the beyond-group-cohomology SPTs. We find new examples of mixed gauge-gravity actions for U(1) SPTs in (4+1)D via the gravitational Chern-Simons term. Field theory representations of SPT invariants not only serve as tools for classifying SPTs, but also guide us in designing physical probes for them. In addition, our field theory representations are independently powerful for studying group cohomology within the mathematical context.

The Formation of Metal (M=Co(II), Ni(II), and Cu(II)) Complexes by Aminosilanes Immobilized within Mesoporous Molecular Sieves

International Nuclear Information System (INIS)

Park, Dong Ho; Park, Sung Soo; Choe, Sang Joon

1999-01-01

The immobilization of APTMS(3-(2-aminoethylamino)propyltrimethoxysilane) and AAPTMS(3-(2-(2-aminoethyl) aminoethylamino)propyltrimethoxysilane) on the surface of high quality mesoporous molecular sieves MCM-41 and MCM-48 have been confirmed by F.T.-IR spectroscopy, Raman spectroscopy, 29 Si solid state NMR, and a surface polarity measurement using Reichardt's dye. The formation of metal (Co(II), Ni(II), and Cu(II)) complexes by immobilized aminosilanes have been investigated by photoacoustic spectroscopy(PAS). The assignment of UV-Vis. PAS bands makes it possible to identify the structure of metal complexes within mesoporous molecular sieves. Co(II) ion may be coordinated mainly in a tetrahedral symmetry by two APTMS onto MCM-41, and in an octahedral one by two AAPTMS. Both Ni(II) and Cu(II) coordinated by aminosilanes within MCM-41 form possibly the octahedral complexes such as [Ni(APTMS) 2 (H 2 O) 2 ] 2+ , [Ni(AAPTMS) 2 ] 2+ , [Cu(APTMS) 2 (H 2 O) 2 ] 2+ , and [Cu(AAPTMS)(H 2 O) 3 ] 2+ , respectively. The PAS band shapes of complexes onto MCM-48 are similar to those of corresponding MCM-41 with the variation of PAS intensity. Most of metal ion(II) within MCM-41 and MCM-48 are coordinated by aminosilanes without the impregnation on the surface

On density of the Vassiliev invariants

DEFF Research Database (Denmark)

Røgen, Peter

1999-01-01

The main result is that the Vassiliev invariants are dense in the set of numeric knot invariants if and only if they separate knots.Keywords: Knots, Vassiliev invariants, separation, density, torus knots......The main result is that the Vassiliev invariants are dense in the set of numeric knot invariants if and only if they separate knots.Keywords: Knots, Vassiliev invariants, separation, density, torus knots...

Quantum implications of a scale invariant regularization

Science.gov (United States)

Ghilencea, D. M.

2018-04-01

We study scale invariance at the quantum level in a perturbative approach. For a scale-invariant classical theory, the scalar potential is computed at a three-loop level while keeping manifest this symmetry. Spontaneous scale symmetry breaking is transmitted at a quantum level to the visible sector (of ϕ ) by the associated Goldstone mode (dilaton σ ), which enables a scale-invariant regularization and whose vacuum expectation value ⟨σ ⟩ generates the subtraction scale (μ ). While the hidden (σ ) and visible sector (ϕ ) are classically decoupled in d =4 due to an enhanced Poincaré symmetry, they interact through (a series of) evanescent couplings ∝ɛ , dictated by the scale invariance of the action in d =4 -2 ɛ . At the quantum level, these couplings generate new corrections to the potential, as scale-invariant nonpolynomial effective operators ϕ2 n +4/σ2 n. These are comparable in size to "standard" loop corrections and are important for values of ϕ close to ⟨σ ⟩. For n =1 , 2, the beta functions of their coefficient are computed at three loops. In the IR limit, dilaton fluctuations decouple, the effective operators are suppressed by large ⟨σ ⟩, and the effective potential becomes that of a renormalizable theory with explicit scale symmetry breaking by the DR scheme (of μ =constant).

Early characteristic radiographic changes in mucolipidosis II

Energy Technology Data Exchange (ETDEWEB)

Lai, Lillian M. [Lucile Packard Children' s Hospital and Stanford University, Pediatric Radiology, Palo Alto, CA (United States); Lachman, Ralph S. [Lucile Packard Children' s Hospital and Stanford University, Pediatric Radiology, Palo Alto, CA (United States); University of California, International Skeletal Dysplasia Registry, Los Angeles, CA (United States)

2016-11-15

Although mucolipidosis type II has similar metabolic abnormalities to those found in all the mucopolysaccharidoses and mucolipidoses, there are distinctive diagnostic radiographic changes of mucolipidosis II in the perinatal/newborn/infant period. To describe the early characteristic radiographic changes of mucolipidosis II and to document when these changes manifest and resolve. We retrospectively reviewed radiographs and clinical records of 19 cases of mucolipidosis II from the International Skeletal Dysplasia Registry (1971-present; fetal age to 21/2 years). A radiologist with special expertise in skeletal dysplasias evaluated the radiographs. The most common abnormalities were increased vertebral body height (80%, nonspecific), talocalcaneal stippling (86%), periosteal cloaking (74%) and vertebral body rounding (50%). Unreported findings included sacrococcygeal sclerosis (54%) and vertebral body sclerosis (13%). Rickets and hyperparathyroidism-like (pseudohyperparathyroidism) changes (rarely reported) were found in 33% of cases. These changes invariably started in the newborn period and resolved by 1 year of age. The conversion from these early infantile radiographic features to dysostosis multiplex changes occurred in 41% of cases, and within the first year after birth. Several findings strongly suggest the diagnosis of mucolipidosis II, including cloaking in combination with one or more of the following radiographic criteria: talocalcaneal stippling, sacrococcygeal or generalized vertebral body sclerosis, vertebral body rounding, or rickets/hyperparathyroidism-like changes in the perinatal/newborn/infancy period. These findings are not found in the other two forms of mucolipidosis nor in any of the mucopolysaccharidoses. (orig.)

Early characteristic radiographic changes in mucolipidosis II

International Nuclear Information System (INIS)

Lai, Lillian M.; Lachman, Ralph S.

2016-01-01

Although mucolipidosis type II has similar metabolic abnormalities to those found in all the mucopolysaccharidoses and mucolipidoses, there are distinctive diagnostic radiographic changes of mucolipidosis II in the perinatal/newborn/infant period. To describe the early characteristic radiographic changes of mucolipidosis II and to document when these changes manifest and resolve. We retrospectively reviewed radiographs and clinical records of 19 cases of mucolipidosis II from the International Skeletal Dysplasia Registry (1971-present; fetal age to 21/2 years). A radiologist with special expertise in skeletal dysplasias evaluated the radiographs. The most common abnormalities were increased vertebral body height (80%, nonspecific), talocalcaneal stippling (86%), periosteal cloaking (74%) and vertebral body rounding (50%). Unreported findings included sacrococcygeal sclerosis (54%) and vertebral body sclerosis (13%). Rickets and hyperparathyroidism-like (pseudohyperparathyroidism) changes (rarely reported) were found in 33% of cases. These changes invariably started in the newborn period and resolved by 1 year of age. The conversion from these early infantile radiographic features to dysostosis multiplex changes occurred in 41% of cases, and within the first year after birth. Several findings strongly suggest the diagnosis of mucolipidosis II, including cloaking in combination with one or more of the following radiographic criteria: talocalcaneal stippling, sacrococcygeal or generalized vertebral body sclerosis, vertebral body rounding, or rickets/hyperparathyroidism-like changes in the perinatal/newborn/infancy period. These findings are not found in the other two forms of mucolipidosis nor in any of the mucopolysaccharidoses. (orig.)

Structure and Function of p97 and Pex1/6 Type II AAA+ Complexes.

Science.gov (United States)

Saffert, Paul; Enenkel, Cordula; Wendler, Petra

2017-01-01

Protein complexes of the Type II AAA+ (ATPases associated with diverse cellular activities) family are typically hexamers of 80-150 kDa protomers that harbor two AAA+ ATPase domains. They form double ring assemblies flanked by associated domains, which can be N-terminal, intercalated or C-terminal to the ATPase domains. Most prominent members of this family include NSF (N-ethyl-maleimide sensitive factor), p97/VCP (valosin-containing protein), the Pex1/Pex6 complex and Hsp104 in eukaryotes and ClpB in bacteria. Tremendous efforts have been undertaken to understand the conformational dynamics of protein remodeling type II AAA+ complexes. A uniform mode of action has not been derived from these works. This review focuses on p97/VCP and the Pex1/6 complex, which both structurally remodel ubiquitinated substrate proteins. P97/VCP plays a role in many processes, including ER- associated protein degradation, and the Pex1/Pex6 complex dislocates and recycles the transport receptor Pex5 from the peroxisomal membrane during peroxisomal protein import. We give an introduction into existing knowledge about the biochemical and cellular activities of the complexes before discussing structural information. We particularly emphasize recent electron microscopy structures of the two AAA+ complexes and summarize their structural differences.

Nhe I and Hinc II polymorphisms in the human laminin B1 chain gene on 7q22

Energy Technology Data Exchange (ETDEWEB)

Pikkarainen, T; Savolainen, E R; Tryggvason, K [Univ. of Oulu (Finland)

1989-06-12

pHL-40 and pHL-42 are overlapping cDNA clones that code for 4.2 kb of the 3{prime} end of the 5.5 kb mRNA. Nhe I detects a two allele polymorphism with fragments of 4.3 kb or 4.0 kb and an invariant band of 10.0 kb. Hinc II detects a two allele polymorphism with fragments of 6.6 kb or 5.5 kb and 1.1 kb and invariant bands of 7.8 kb, 4.0 kb, 3.3 kb, 2.3 kb and 0.6 kb. The allele frequency was studied in 60 chromosomes of unrelated Finnish individuals. The probe was localized to chromosome 7q22 by somatic cell and in situ hybridization. Co-dominant inheritance of the Nhe I RFLP was shown in one family and of the Hinc II RFLP in five families.

Mono(p-tolyl)platinum(II) and bis(p-tolyl)platinum(II) complexes of diethylsulfide as reagents for organoplatinum synthesis. Structures of [Pt(p-Tol)2(µ-SEt2)]2 and PtCl(p-Tol)(bpy) (bpy = 2,2'-bipyridine)

NARCIS (Netherlands)

Koten, G. van; Casado Lacabra, M.A.; Canty, A.J.; Lutz, M.H.; Patel, J.; Spek, A.L.; Sun, H.

2001-01-01

The complex trans-PtCl(p-Tol)(SEt{2}){2} is obtained from the reaction of [Pt(p-Tol){2}(SEt{2})]{2} with PtCl{2}(SEt{2}){2} and SEt{2} in mole ratio 1:2:2. The mono(p-tolyl)platinum(II) and bis(p-tolyl)platinum(II) complexes of diethylsulfide react with 2, 2'-bipyridine to form the complexes

28 CFR 66.41 - Financial reporting.

Science.gov (United States)

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Financial reporting. 66.41 Section 66.41..., Retention, and Enforcement § 66.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a..., for: (i) Submitting financial reports to Federal agencies, or (ii) Requesting advances or...

29 CFR 1470.41 - Financial reporting.

Science.gov (United States)

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Financial reporting. 1470.41 Section 1470.41 Labor... Reports, Records Retention, and Enforcement § 1470.41 Financial reporting. (a) General. (1) Except as... authorized by OMB, for: (i) Submitting financial reports to Federal agencies, or (ii) Requesting advances or...

Cohomological invariants in Galois cohomology

CERN Document Server

Garibaldi, Skip; Serre, Jean Pierre

2003-01-01

This volume is concerned with algebraic invariants, such as the Stiefel-Whitney classes of quadratic forms (with values in Galois cohomology mod 2) and the trace form of �tale algebras (with values in the Witt ring). The invariants are analogues for Galois cohomology of the characteristic classes of topology. Historically, one of the first examples of cohomological invariants of the type considered here was the Hasse-Witt invariant of quadratic forms. The first part classifies such invariants in several cases. A principal tool is the notion of versal torsor, which is an analogue of the universal bundle in topology. The second part gives Rost's determination of the invariants of G-torsors with values in H^3(\\mathbb{Q}/\\mathbb{Z}(2)), when G is a semisimple, simply connected, linear group. This part gives detailed proofs of the existence and basic properties of the Rost invariant. This is the first time that most of this material appears in print.

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility.

Science.gov (United States)

Pancera, Marie; Majeed, Shahzad; Ban, Yih-En Andrew; Chen, Lei; Huang, Chih-chin; Kong, Leopold; Kwon, Young Do; Stuckey, Jonathan; Zhou, Tongqing; Robinson, James E; Schief, William R; Sodroski, Joseph; Wyatt, Richard; Kwong, Peter D

2010-01-19

The viral spike of HIV-1 is composed of three gp120 envelope glycoproteins attached noncovalently to three gp41 transmembrane molecules. Viral entry is initiated by binding to the CD4 receptor on the cell surface, which induces large conformational changes in gp120. These changes not only provide a model for receptor-triggered entry, but affect spike sensitivity to drug- and antibody-mediated neutralization. Although some of the details of the CD4-induced conformational change have been visualized by crystal structures and cryoelectron tomograms, the critical gp41-interactive region of gp120 was missing from previous atomic-level characterizations. Here we determine the crystal structure of an HIV-1 gp120 core with intact gp41-interactive region in its CD4-bound state, compare this structure to unliganded and antibody-bound forms to identify structurally invariant and plastic components, and use ligand-oriented cryoelectron tomograms to define component mobility in the viral spike context. Newly defined gp120 elements proximal to the gp41 interface complete a 7-stranded beta-sandwich, which appeared invariant in conformation. Loop excursions emanating from the sandwich form three topologically separate--and structurally plastic--layers, topped off by the highly glycosylated gp120 outer domain. Crystal structures, cryoelectron tomograms, and interlayer chemistry were consistent with a mechanism in which the layers act as a shape-changing spacer, facilitating movement between outer domain and gp41-associated beta-sandwich and providing for conformational diversity used in immune evasion. A "layered" gp120 architecture thus allows movement among alternative glycoprotein conformations required for virus entry and immune evasion, whereas a beta-sandwich clamp maintains gp120-gp41 interaction and regulates gp41 transitions.

Cosmological disformal invariance

Energy Technology Data Exchange (ETDEWEB)

Domènech, Guillem; Sasaki, Misao [Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan); Naruko, Atsushi, E-mail: guillem.domenech@yukawa.kyoto-u.ac.jp, E-mail: naruko@th.phys.titech.ac.jp, E-mail: misao@yukawa.kyoto-u.ac.jp [Department of Physics, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan)

2015-10-01

The invariance of physical observables under disformal transformations is considered. It is known that conformal transformations leave physical observables invariant. However, whether it is true for disformal transformations is still an open question. In this paper, it is shown that a pure disformal transformation without any conformal factor is equivalent to rescaling the time coordinate. Since this rescaling applies equally to all the physical quantities, physics must be invariant under a disformal transformation, that is, neither causal structure, propagation speed nor any other property of the fields are affected by a disformal transformation itself. This fact is presented at the action level for gravitational and matter fields and it is illustrated with some examples of observable quantities. We also find the physical invariance for cosmological perturbations at linear and high orders in perturbation, extending previous studies. Finally, a comparison with Horndeski and beyond Horndeski theories under a disformal transformation is made.

Conformal branching rules and modular invariants

International Nuclear Information System (INIS)

Walton, M.A.

1989-01-01

Using the outer automorphisms of the affine algebra SU(n), we show how the branching rules for the conformal subalgebra SU(pq) contains SU(p) x SU(q) may be simply calculated. We demonstrate that new modular invariant combinations of SU(n) characters are obtainable from the branching rules. (orig.)

Histone acetyltransferase (HAT) activity of p300 modulates human T lymphotropic virus type 1 p30II-mediated repression of LTR transcriptional activity

International Nuclear Information System (INIS)

Michael, Bindhu; Nair, Amrithraj M.; Datta, Antara; Hiraragi, Hajime; Ratner, Lee; Lairmore, Michael D.

2006-01-01

Human T-lymphotropic virus type-1 (HTLV-1) is a deltaretrovirus that causes adult T cell leukemia/lymphoma, and is implicated in a variety of lymphocyte-mediated inflammatory disorders. HTLV-1 provirus has regulatory and accessory genes in four pX open reading frames. HTLV-1 pX ORF-II encodes two proteins, p13 II and p30 II , which are incompletely defined in virus replication or pathogenesis. We have demonstrated that pX ORF-II mutations block virus replication in vivo and that ORF-II encoded p30 II , a nuclear-localizing protein that binds with CREB-binding protein (CBP)/p300, represses CREB and Tax responsive element (TRE)-mediated transcription. Herein, we have identified p30 II motifs important for p300 binding and in regulating TRE-mediated transcription in the absence and presence of HTLV-1 provirus. Within amino acids 100-179 of p30 II , a region important for repression of LTR-mediated transcription, we identified a single lysine residue at amino acid 106 (K3) that significantly modulates the ability of p30 II to repress TRE-mediated transcription. Exogenous p300, in a dose-responsive manner, reverses p30 II -dependent repression of TRE-mediated transcription, in the absence or presence of the provirus, In contrast to wild type p300, p300 HAT mutants (defective in histone acetyltransferase activity) only partially rescued p30 II -mediated LTR repression. Deacetylation by histone deacetylase-1 (HDAC-1) enhanced p30 II -mediated LTR repression, while inhibition of deacetylation by trichostatin A decreases p30 II -mediated LTR repression. Collectively, our data indicate that HTLV-1 p30 II modulates viral gene expression in a cooperative manner with p300-mediated acetylation

Donaldson invariants in algebraic geometry

International Nuclear Information System (INIS)

Goettsche, L.

2000-01-01

In these lectures I want to give an introduction to the relation of Donaldson invariants with algebraic geometry: Donaldson invariants are differentiable invariants of smooth compact 4-manifolds X, defined via moduli spaces of anti-self-dual connections. If X is an algebraic surface, then these moduli spaces can for a suitable choice of the metric be identified with moduli spaces of stable vector bundles on X. This can be used to compute Donaldson invariants via methods of algebraic geometry and has led to a lot of activity on moduli spaces of vector bundles and coherent sheaves on algebraic surfaces. We will first recall the definition of the Donaldson invariants via gauge theory. Then we will show the relation between moduli spaces of anti-self-dual connections and moduli spaces of vector bundles on algebraic surfaces, and how this makes it possible to compute Donaldson invariants via algebraic geometry methods. Finally we concentrate on the case that the number b + of positive eigenvalues of the intersection form on the second homology of the 4-manifold is 1. In this case the Donaldson invariants depend on the metric (or in the algebraic geometric case on the polarization) via a system of walls and chambers. We will study the change of the invariants under wall-crossing, and use this in particular to compute the Donaldson invariants of rational algebraic surfaces. (author)

All Chern-Simons invariants of 4D, N=1 gauged superform hierarchies

Energy Technology Data Exchange (ETDEWEB)

Becker, Katrin; Becker, Melanie; III, William D. Linch [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy,Texas A& M University,College Station, TX 77843-4242 (United States); Randall, Stephen [Department of Physics, University of California,Berkeley, CA 94720-7300 (United States); Robbins, Daniel [Department of Physics, University at Albany,Albany, NY 12222 (United States)

2017-04-19

We give a geometric description of supersymmetric gravity/(non-)abelian p-form hierarchies in superspaces with 4D, N=1 super-Poincaré invariance. These hierarchies give rise to Chern-Simons-like invariants, such as those of the 5D, N=1 graviphoton and the eleven-dimensional 3-form but also generalizations such as Green-Schwarz-like/BF-type couplings. Previous constructions based on prepotential superfields are reinterpreted in terms of p-forms in superspace thereby elucidating the underlying geometry. This vastly simplifies the calculations of superspace field-strengths, Bianchi identities, and Chern-Simons invariants. Using this, we prove the validity of a recursive formula for the conditions defining these actions for any such tensor hierarchy. Solving it at quadratic and cubic orders, we recover the known results for the BF-type and cubic Chern-Simons actions. As an application, we compute the quartic invariant ∼AdAdAdA+… relevant, for example, to seven-dimensional supergravity compactifications.

Moment invariants for particle beams

International Nuclear Information System (INIS)

Lysenko, W.P.; Overley, M.S.

1988-01-01

The rms emittance is a certain function of second moments in 2-D phase space. It is preserved for linear uncoupled (1-D) motion. In this paper, the authors present new functions of moments that are invariants for coupled motion. These invariants were computed symbolically using a computer algebra system. Possible applications for these invariants are discussed. Also, approximate moment invariants for nonlinear motion are presented

Can confinement ensure natural CP-invariance of strong interactions

International Nuclear Information System (INIS)

Shifman, M.A.; Vainshtein, A.I.; Zakharov, V.I.

1979-01-01

P- and T-invariance violation in quantum chromodynamics (QCD) due to the so called THETA term Δα=THETAxgsub(s)sup(2)/32πsup(2)xGsub(μν)sup(a)xGsub(μν)sup(a) tilde, where Gsub(μν)sup(a) is the gluon field strength tensor, and gsub(s) is the quark-gluon coupling constant is discussed. It is shown that irrespectively of how the confinement works there emerge observable P- and T-odd effects. The proof is based on the assumption that QCD resolves the upsilon(1) problem, i.e. the mass of the singlet pseudoscalar meson does not vanish in the chiral limit. A modification of the axion scheme which restores the natural P and T invariance of the theory is suggested and cannot be ruled out experimentally

49 CFR 18.41 - Financial reporting.

Science.gov (United States)

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Financial reporting. 18.41 Section 18.41... Enforcement § 18.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

34 CFR 80.41 - Financial reporting.

Science.gov (United States)

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Financial reporting. 80.41 Section 80.41 Education... Enforcement § 80.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

45 CFR 92.41 - Financial reporting.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Financial reporting. 92.41 Section 92.41 Public... Reports, Records Retention, and Enforcement § 92.41 Financial reporting. (a) General. (1) Except as... authorized by OMB, for: (i) Submitting financial reports to Federal agencies, or (ii) Requesting advances or...

45 CFR 1174.41 - Financial reporting.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Financial reporting. 1174.41 Section 1174.41... Enforcement § 1174.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

45 CFR 1183.41 - Financial reporting.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Financial reporting. 1183.41 Section 1183.41... Enforcement § 1183.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a)(2) and (5) of...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

45 CFR 1157.41 - Financial reporting.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Financial reporting. 1157.41 Section 1157.41... Enforcement § 1157.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

22 CFR 135.41 - Financial reporting.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Financial reporting. 135.41 Section 135.41... Enforcement § 135.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage.

Science.gov (United States)

Hilton, Matthew J; Tu, Xiaolin; Long, Fanxin

2007-08-01

Indian hedgehog (Ihh) controls multiple aspects of endochondral skeletal development by signaling to both chondrocytes and perichondrial cells. Previous efforts to delineate direct effects of Ihh on chondrocytes by Col2-Cre-mediated ablation of Smoothened (Smo, encoding a transmembrane protein indispensable for Ihh signaling) has been only partially successful, due to the inability to discriminate between chondrocytes and perichondrial cells. Here we report a transgenic line (Col2-Cre) expressing under the control of the Colalpha1(II) promoter an inert form of Cre that is activatable by exogenous tamoxifen (TM); TM administration at proper times during embryogenesis induced Cre activity in chondrocytes but not in the perichondrium. By using this mouse line, we deleted Smo within subsets of chondrocytes without affecting the perichondrium and found that Smo removal led to localized disruption of the expression of parathyroid hormone-related protein (PTHrP) and the morphology of chondrocytes. Unexpectedly, TM invariably induced Cre activity in a subset of cells associated with the trabecular bone surface of long bones. These cells, when genetically marked and cultured in vitro, were capable of producing bone nodules. Expression of the Col2-Cre transgene in these cells likely reflected the endogenous Colalpha1(II) promoter activity as similar cells were found to express the IIA isoform of Colalpha1(II) mRNA endogenously. In summary, the present study has not only provided evidence that Ihh signaling directly controls PTHrP expression and chondrocyte morphology in the growth region cartilage, but has also uncovered a distinct cell type associated with the trabecular bone that appears to possess osteogenic potential.

Formation of Hg(II) Tetrathiolate Complexes with Cysteine at Neutral pH.

Science.gov (United States)

Warner, Thomas; Jalilehvand, Farideh

2016-04-01

Mercury(II) ions precipitate from aqueous cysteine (H 2 Cys) solutions containing H 2 Cys/Hg(II) mole ratio ≥ 2.0 as Hg( S -HCys) 2 . In absence of additional cysteine, the precipitate dissolves at pH ~12 with the [Hg( S,N -Cys) 2 ] 2- complex dominating. With excess cysteine (H 2 Cys/Hg(II) mole ratio ≥ 4.0), higher complexes form and the precipitate dissolves at lower pH values. Previously, we found that tetrathiolate [Hg( S -Cys) 4 ] 6- complexes form at pH = 11.0; in this work we extend the investigation to pH values of physiological interest. We examined two series of Hg(II)-cysteine solutions in which C Hg(II) varied between 8 - 9 mM and 80 - 100 mM, respectively, with H 2 Cys/Hg(II) mole ratios from 4 to ~20. The solutions were prepared in the pH range 7.1 - 8.8, at the pH at which the initial Hg( S -HCys) 2 precipitate dissolved. The variations in the Hg(II) speciation were followed by 199 Hg NMR, X-ray absorption and Raman spectroscopic techniques. Our results show that in the dilute solutions ( C Hg(II) = 8 - 9 mM), mixtures of di-, tri- (major) and tetrathiolate complexes exist at moderate cysteine excess ( C H2Cys ~ 0.16 M) at pH 7.1. In the more concentrated solutions ( C Hg(II) = 80 - 100 mM) with high cysteine excess ( C H2Cys > 0.9 M), tetrathiolate [Hg( S -cysteinate) 4 ] m -6 ( m = 0 - 4) complexes dominate in the pH range 7.3 - 7.8, with lower charge than for the [Hg( S -Cys) 4 ] 6- complex due to protonation of some ( m ) of the amino groups of the coordinated cysteine ligands. The results of this investigation could provide a key to the mechanism of biosorption and accumulation of Hg(II) ions in biological / environmental systems.

Permutation-invariant distance between atomic configurations

Science.gov (United States)

Ferré, Grégoire; Maillet, Jean-Bernard; Stoltz, Gabriel

2015-09-01

We present a permutation-invariant distance between atomic configurations, defined through a functional representation of atomic positions. This distance enables us to directly compare different atomic environments with an arbitrary number of particles, without going through a space of reduced dimensionality (i.e., fingerprints) as an intermediate step. Moreover, this distance is naturally invariant through permutations of atoms, avoiding the time consuming associated minimization required by other common criteria (like the root mean square distance). Finally, the invariance through global rotations is accounted for by a minimization procedure in the space of rotations solved by Monte Carlo simulated annealing. A formal framework is also introduced, showing that the distance we propose verifies the property of a metric on the space of atomic configurations. Two examples of applications are proposed. The first one consists in evaluating faithfulness of some fingerprints (or descriptors), i.e., their capacity to represent the structural information of a configuration. The second application concerns structural analysis, where our distance proves to be efficient in discriminating different local structures and even classifying their degree of similarity.

Permutation-invariant distance between atomic configurations

International Nuclear Information System (INIS)

Ferré, Grégoire; Maillet, Jean-Bernard; Stoltz, Gabriel

2015-01-01

We present a permutation-invariant distance between atomic configurations, defined through a functional representation of atomic positions. This distance enables us to directly compare different atomic environments with an arbitrary number of particles, without going through a space of reduced dimensionality (i.e., fingerprints) as an intermediate step. Moreover, this distance is naturally invariant through permutations of atoms, avoiding the time consuming associated minimization required by other common criteria (like the root mean square distance). Finally, the invariance through global rotations is accounted for by a minimization procedure in the space of rotations solved by Monte Carlo simulated annealing. A formal framework is also introduced, showing that the distance we propose verifies the property of a metric on the space of atomic configurations. Two examples of applications are proposed. The first one consists in evaluating faithfulness of some fingerprints (or descriptors), i.e., their capacity to represent the structural information of a configuration. The second application concerns structural analysis, where our distance proves to be efficient in discriminating different local structures and even classifying their degree of similarity

45 CFR 602.41 - Financial reporting.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Financial reporting. 602.41 Section 602.41 Public... Requirements § 602.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

20 CFR 437.41 - Financial reporting.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Financial reporting. 437.41 Section 437.41... Enforcement § 437.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a)(2) and (5) of...) Submitting financial reports to SSA, or (ii) Requesting advances or reimbursements when letters of credit are...

21 CFR 1403.41 - Financial reporting.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Financial reporting. 1403.41 Section 1403.41 Food... Enforcement § 1403.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5...) Submitting financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters...

On the resolution in a measurement of dijet invariant mass when searching for associated WZ production with CDF

Energy Technology Data Exchange (ETDEWEB)

Leo, Sabato [Pisa U.

2009-01-01

We report on a number of simulation studies on how to improve the invariant mass resolution of a particle decaying into two large energy hadron jets. This is a preliminary step of an effort to observe associated WZ production. This process is extremely rare and competes with a large background, and any even minor improvement in resolution deserves great attention. ....

Feedback-Driven Dynamic Invariant Discovery

Science.gov (United States)

Zhang, Lingming; Yang, Guowei; Rungta, Neha S.; Person, Suzette; Khurshid, Sarfraz

2014-01-01

Program invariants can help software developers identify program properties that must be preserved as the software evolves, however, formulating correct invariants can be challenging. In this work, we introduce iDiscovery, a technique which leverages symbolic execution to improve the quality of dynamically discovered invariants computed by Daikon. Candidate invariants generated by Daikon are synthesized into assertions and instrumented onto the program. The instrumented code is executed symbolically to generate new test cases that are fed back to Daikon to help further re ne the set of candidate invariants. This feedback loop is executed until a x-point is reached. To mitigate the cost of symbolic execution, we present optimizations to prune the symbolic state space and to reduce the complexity of the generated path conditions. We also leverage recent advances in constraint solution reuse techniques to avoid computing results for the same constraints across iterations. Experimental results show that iDiscovery converges to a set of higher quality invariants compared to the initial set of candidate invariants in a small number of iterations.

Relating measurement invariance, cross-level invariance, and multilevel reliability

OpenAIRE

Jak, S.; Jorgensen, T.D.

2017-01-01

Data often have a nested, multilevel structure, for example when data are collected from children in classrooms. This kind of data complicate the evaluation of reliability and measurement invariance, because several properties can be evaluated at both the individual level and the cluster level, as well as across levels. For example, cross-level invariance implies equal factor loadings across levels, which is needed to give latent variables at the two levels a similar interpretation. Reliabili...

Constraint quantization of a worldline system invariant under reciprocal relativity: II

International Nuclear Information System (INIS)

Jarvis, P D; Morgan, S O

2008-01-01

We consider the worldline quantization of a system invariant under the symmetries of reciprocal relativity. Imposition of the first class constraint, the generator of local time reparametrizations, on physical states enforces identification of the worldline cosmological constant with a fixed value of the quadratic Casimir of the quaplectic symmetry group Q(3, 1) ≅ U(3, 1) x H(4), the semi-direct product of the pseudo-unitary group with the Weyl-Heisenberg group. In our previous paper, J. Phys. A: Math. Theor. 40 (2007) 12095, the 'spin' degrees of freedom were handled as covariant oscillators, leading to a unique choice of cosmological constant, required for projecting out negative-norm states from the physical gauge-invariant states. In the present paper, the spin degrees of freedom are treated as standard oscillators with positive norm states (wherein Lorentz boosts are not number-conserving in the auxiliary space; reciprocal transformations are of course not spin-conserving in general). As in the covariant approach, the spectrum of the square of the energy-momentum vector is continuous over the entire real line, and thus includes tachyonic (spacelike) and null branches. Adopting standard frames, the Wigner method on each branch is implemented, to decompose the auxiliary space into unitary irreducible representations of the respective little algebras and additional degeneracy algebras. The physical state space is vastly enriched as compared with the covariant approach, and contains towers of integer spin massive states, as well as unconventional massless representations of continuous spin type, with continuous Euclidean momentum and arbitrary integer helicity

Constraint quantization of a worldline system invariant under reciprocal relativity: II

Energy Technology Data Exchange (ETDEWEB)

Jarvis, P D; Morgan, S O [School of Mathematics and Physics, University of Tasmania, Private Bag 37 Hobart, Tasmania 7001 (Australia)], E-mail: Peter.Jarvis@utas.edu.au, E-mail: Stuart.Morgan@utas.edu.au

2008-11-21

We consider the worldline quantization of a system invariant under the symmetries of reciprocal relativity. Imposition of the first class constraint, the generator of local time reparametrizations, on physical states enforces identification of the worldline cosmological constant with a fixed value of the quadratic Casimir of the quaplectic symmetry group Q(3, 1) {approx_equal} U(3, 1) x H(4), the semi-direct product of the pseudo-unitary group with the Weyl-Heisenberg group. In our previous paper, J. Phys. A: Math. Theor. 40 (2007) 12095, the 'spin' degrees of freedom were handled as covariant oscillators, leading to a unique choice of cosmological constant, required for projecting out negative-norm states from the physical gauge-invariant states. In the present paper, the spin degrees of freedom are treated as standard oscillators with positive norm states (wherein Lorentz boosts are not number-conserving in the auxiliary space; reciprocal transformations are of course not spin-conserving in general). As in the covariant approach, the spectrum of the square of the energy-momentum vector is continuous over the entire real line, and thus includes tachyonic (spacelike) and null branches. Adopting standard frames, the Wigner method on each branch is implemented, to decompose the auxiliary space into unitary irreducible representations of the respective little algebras and additional degeneracy algebras. The physical state space is vastly enriched as compared with the covariant approach, and contains towers of integer spin massive states, as well as unconventional massless representations of continuous spin type, with continuous Euclidean momentum and arbitrary integer helicity.

Gauge invariant Barr-Zee type contributions to fermionic EDMs in the two-Higgs doublet models

International Nuclear Information System (INIS)

Abe, Tomohiro; Hisano, Junji; Kitahara, Teppei; Tobioka, Kohsaku

2014-01-01

We calculate all gauge invariant Barr-Zee type contributions to fermionic electric dipole moments (EDMs) in the two-Higgs doublet models (2HDM) with softly broken Z 2 symmetry. We start by studying the tensor structure of h→VV′ part in the Barr-Zee diagrams, and we calculate the effective couplings in a gauge invariant way by using the pinch technique. Then we calculate all Barr-Zee diagrams relevant for electron and neutron EDMs. We make bounds on the parameter space in type-I, type-II, type-X, and type-Y 2HDMs. The electron and neutron EDMs are complementary to each other in discrimination of the 2HDMs. Type-II and type-X 2HDMs are strongly constrained by recent ACME experiment’s result, and future experiments of electron and neutron EDMs may search O(10) TeV physics

Mitochondrial ribosomal protein L41 mediates serum starvation-induced cell-cycle arrest through an increase of p21WAF1/CIP1

International Nuclear Information System (INIS)

Kim, Mi Jin; Yoo, Young A.; Kim, Hyung Jung; Kang, Seongman; Kim, Yong Geon; Kim, Jun Suk; Yoo, Young Do

2005-01-01

Ribosomal proteins not only act as components of the translation apparatus but also regulate cell proliferation and apoptosis. A previous study reported that MRPL41 plays an important role in p53-dependent apoptosis. It also showed that MRPL41 arrests the cell cycle by stabilizing p27 Kip1 in the absence of p53. This study found that MRPL41 mediates the p21 WAF1/CIP1 -mediated G1 arrest in response to serum starvation. The cells were released from serum starvation-induced G1 arrest via the siRNA-mediated blocking of MRPL41 expression. Overall, these results suggest that MRPL41 arrests the cell cycle by increasing the p21 WAF1/CIP1 and p27 Kip1 levels under the growth inhibitory conditions

Foliated vector fields, the Godbillon-Vey invariant and the invariant I(F)

International Nuclear Information System (INIS)

Banyaga, A.; Landa, Alain Musesa

2004-03-01

We prove that if the invariant I(F) constructed in 'An invariant of contact structures and transversally oriented foliations', Ann. Global Analysis and Geom. 14(1996) 427-441 (A. Banyaga), through the Lie algebra of infinitesimal automorphisms of transversally oriented foliations F is trivial, then the Godbillon-Vey invariant GV (F) of F is also trivial, but that the converse is not true. For codimension one foliations, the restrictions I τ , (F) of I(F) to the Lie subalgebra of vector fields tangent to the leaves is the Reeb class R(F) of F. We also prove that if there exists a foliated vector field which is everywhere transverse to a codimension one foliation, then the Reeb class R(F) is trivial, hence so is the GV(F) invariant. (author)

Global solvability of the differential operators non-invariants on semi-simple Lie groups

International Nuclear Information System (INIS)

El Hussein, K.

1991-09-01

Let G be a connected semi-simple Lie group with finite centre and let G=KAN be the Iwasawa decomposition of G. Let P be a differential operator on G, which is right invariant by the sub-group AN and left invariant by the sub-group K. In this paper, we give a necessary and sufficient condition for the global solvability of P on G. (author). 5 refs

78 FR 77770 - Aldine Capital Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

Science.gov (United States)

2013-12-24

... financing to Koontz-Wagner Maintenance Services, LLC., 3801 Voorde Drive, South Bend, IN 46628. The....P. is an Associate of Aldine Capital Fund II, L.P. and owns more than ten percent of Koontz- Wagner...

Electrosensory Midbrain Neurons Display Feature Invariant Responses to Natural Communication Stimuli.

Directory of Open Access Journals (Sweden)

Tristan Aumentado-Armstrong

2015-10-01

Full Text Available Neurons that respond selectively but in an invariant manner to a given feature of natural stimuli have been observed across species and systems. Such responses emerge in higher brain areas, thereby suggesting that they occur by integrating afferent input. However, the mechanisms by which such integration occurs are poorly understood. Here we show that midbrain electrosensory neurons can respond selectively and in an invariant manner to heterogeneity in behaviorally relevant stimulus waveforms. Such invariant responses were not seen in hindbrain electrosensory neurons providing afferent input to these midbrain neurons, suggesting that response invariance results from nonlinear integration of such input. To test this hypothesis, we built a model based on the Hodgkin-Huxley formalism that received realistic afferent input. We found that multiple combinations of parameter values could give rise to invariant responses matching those seen experimentally. Our model thus shows that there are multiple solutions towards achieving invariant responses and reveals how subthreshold membrane conductances help promote robust and invariant firing in response to heterogeneous stimulus waveforms associated with behaviorally relevant stimuli. We discuss the implications of our findings for the electrosensory and other systems.

Electrosensory Midbrain Neurons Display Feature Invariant Responses to Natural Communication Stimuli.

Science.gov (United States)

Aumentado-Armstrong, Tristan; Metzen, Michael G; Sproule, Michael K J; Chacron, Maurice J

2015-10-01

Neurons that respond selectively but in an invariant manner to a given feature of natural stimuli have been observed across species and systems. Such responses emerge in higher brain areas, thereby suggesting that they occur by integrating afferent input. However, the mechanisms by which such integration occurs are poorly understood. Here we show that midbrain electrosensory neurons can respond selectively and in an invariant manner to heterogeneity in behaviorally relevant stimulus waveforms. Such invariant responses were not seen in hindbrain electrosensory neurons providing afferent input to these midbrain neurons, suggesting that response invariance results from nonlinear integration of such input. To test this hypothesis, we built a model based on the Hodgkin-Huxley formalism that received realistic afferent input. We found that multiple combinations of parameter values could give rise to invariant responses matching those seen experimentally. Our model thus shows that there are multiple solutions towards achieving invariant responses and reveals how subthreshold membrane conductances help promote robust and invariant firing in response to heterogeneous stimulus waveforms associated with behaviorally relevant stimuli. We discuss the implications of our findings for the electrosensory and other systems.

Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30{sup II} accessory protein and the induction of oncogenic cellular transformation by p30{sup II}/c-MYC

Energy Technology Data Exchange (ETDEWEB)

Romeo, Megan M.; Ko, Bookyung; Kim, Janice; Brady, Rebecca; Heatley, Hayley C.; He, Jeffrey; Harrod, Carolyn K.; Barnett, Braden [Laboratory of Molecular Virology, Department of Biological Sciences, and The Dedman College Center for Drug Discovery, Design, and Delivery, Southern Methodist University, Dallas, TX 75275-0376 (United States); Ratner, Lee [Departments of Medicine and Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110 (United States); Lairmore, Michael D. [University of California-Davis, School of Veterinary Medicine, One Shields Avenue, Davis, CA 95618 (United States); Martinez, Ernest [Department of Biochemistry, University of California, Riverside, CA 92521 (United States); Lüscher, Bernhard [Institute of Biochemistry, Klinikum, RWTH Aachen University, Pauwelsstrasse 30, 52057 Aachen (Germany); Robson, Craig N. [Northern Institute for Cancer Research, Newcastle University, The Medical School, Newcastle upon Tyne, NE2 4HH (United Kingdom); Henriksson, Marie [Department of Microbiology, Cell and Tumor Biology, Karolinska Institutet, Stockholm (Sweden); Harrod, Robert, E-mail: rharrod@smu.edu [Laboratory of Molecular Virology, Department of Biological Sciences, and The Dedman College Center for Drug Discovery, Design, and Delivery, Southern Methodist University, Dallas, TX 75275-0376 (United States)

2015-02-15

The human T-cell leukemia retrovirus type-1 (HTLV-1) p30{sup II} protein is a multifunctional latency-maintenance factor that negatively regulates viral gene expression and deregulates host signaling pathways involved in aberrant T-cell growth and proliferation. We have previously demonstrated that p30{sup II} interacts with the c-MYC oncoprotein and enhances c-MYC-dependent transcriptional and oncogenic functions. However, the molecular and biochemical events that mediate the cooperation between p30{sup II} and c-MYC remain to be completely understood. Herein we demonstrate that p30{sup II} induces lysine-acetylation of the c-MYC oncoprotein. Acetylation-defective c-MYC Lys→Arg substitution mutants are impaired for oncogenic transformation with p30{sup II} in c-myc{sup −/−} HO15.19 fibroblasts. Using dual-chromatin-immunoprecipitations (dual-ChIPs), we further demonstrate that p30{sup II} is present in c-MYC-containing nucleoprotein complexes in HTLV-1-transformed HuT-102 T-lymphocytes. Moreover, p30{sup II} inhibits apoptosis in proliferating cells expressing c-MYC under conditions of genotoxic stress. These findings suggest that c-MYC-acetylation is required for the cooperation between p30{sup II}/c-MYC which could promote proviral replication and contribute to HTLV-1-induced carcinogenesis. - Highlights: • Acetylation of c-MYC is required for oncogenic transformation by HTLV-1 p30{sup II}/c-MYC. • Acetylation-defective c-MYC mutants are impaired for foci-formation by p30{sup II}/c-MYC. • The HTLV-1 p30{sup II} protein induces lysine-acetylation of c-MYC. • p30{sup II} is present in c-MYC nucleoprotein complexes in HTLV-1-transformed T-cells. • HTLV-1 p30{sup II} inhibits apoptosis in c-MYC-expressing proliferating cells.

Gauge invariance rediscovered

International Nuclear Information System (INIS)

Moriyasu, K.

1978-01-01

A pedagogical approach to gauge invariance is presented which is based on the analogy between gauge transformations and relativity. By using the concept of an internal space, purely geometrical arguments are used to teach the physical ideas behind gauge invariance. Many of the results are applicable to general gauge theories

Translation invariant time-dependent solutions to massive gravity II

Science.gov (United States)

Mourad, J.; Steer, D. A.

2014-06-01

This paper is a sequel to JCAP 12 (2013) 004 and is also devoted to translation-invariant solutions of ghost-free massive gravity in its moving frame formulation. Here we consider a mass term which is linear in the vielbein (corresponding to a β3 term in the 4D metric formulation) in addition to the cosmological constant. We determine explicitly the constraints, and from the initial value formulation show that the time-dependent solutions can have singularities at a finite time. Although the constraints give, as in the β1 case, the correct number of degrees of freedom for a massive spin two field, we show that the lapse function can change sign at a finite time causing a singular time evolution. This is very different to the β1 case where time evolution is always well defined. We conclude that the β3 mass term can be pathological and should be treated with care.

o-Vanillin functionalized mesoporous silica - coated magnetite nanoparticles for efficient removal of Pb(II) from water

Science.gov (United States)

Culita, Daniela C.; Simonescu, Claudia Maria; Patescu, Rodica-Elena; Dragne, Mioara; Stanica, Nicolae; Oprea, Ovidiu

2016-06-01

o-Vanillin functionalized mesoporous silica - coated magnetite (Fe3O4@MCM-41-N-oVan) was synthesized and fully characterized by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, N2 adsorption-desorption technique and magnetic measurements. The capacity of Fe3O4@MCM-41-N-oVan to adsorb Pb(II) from aqueous solutions was evaluated in comparison with raw mesoporous silica - coated magnetite (Fe3O4@MCM-41) and amino - modified mesoporous silica coated magnetite (Fe3O4@MCM-41-NH2). The effect of adsorption process parameters such us pH, contact time, initial Pb(II) concentration was also investigated. The adsorption data were successfully fitted with the Langmuir model, exhibiting a maximum adsorption capacity of 155.71 mg/g at pH=4.4 and T=298 K. The results revealed that the adsorption rate was very high at the beginning of the adsorption process, 80-90% of the total amount of Pb(II) being removed within the first 60 min, depending on the initial concentration. The results of the present work suggest that Fe3O4@MCM-41-N-oVan is a suitable candidate for the separation of Pb(II) from contaminated water.

Link invariants from finite Coxeter racks

OpenAIRE

Nelson, Sam; Wieghard, Ryan

2008-01-01

We study Coxeter racks over $\\mathbb{Z}_n$ and the knot and link invariants they define. We exploit the module structure of these racks to enhance the rack counting invariants and give examples showing that these enhanced invariants are stronger than the unenhanced rack counting invariants.

Poincare-Birkhoff-Witt theorems and generalized Casimir invariants for some infinite-dimensional Lie groups: II

International Nuclear Information System (INIS)

Ton-That, Tuong

2005-01-01

In a previous paper we gave a generalization of the notion of Casimir invariant differential operators for the infinite-dimensional Lie groups GL ∞ (C) (or equivalently, for its Lie algebra gj ∞ (C)). In this paper we give a generalization of the Casimir invariant differential operators for a class of infinite-dimensional Lie groups (or equivalently, for their Lie algebras) which contains the infinite-dimensional complex classical groups. These infinite-dimensional Lie groups, and their Lie algebras, are inductive limits of finite-dimensional Lie groups, and their Lie algebras, with some additional properties. These groups or their Lie algebras act via the generalized adjoint representations on projective limits of certain chains of vector spaces of universal enveloping algebras. Then the generalized Casimir operators are the invariants of the generalized adjoint representations. In order to be able to explicitly compute the Casimir operators one needs a basis for the universal enveloping algebra of a Lie algebra. The Poincare-Birkhoff-Witt (PBW) theorem gives an explicit construction of such a basis. Thus in the first part of this paper we give a generalization of the PBW theorem for inductive limits of Lie algebras. In the last part of this paper a generalization of the very important theorem in representation theory, namely the Chevalley-Racah theorem, is also discussed

Synthesis and properties of complexes of copper(II), nickel(II), cobalt(II) and uranyl ions with 3-(p-tolylsulphonamido)rhodamine

International Nuclear Information System (INIS)

El-Bindary, A.A.; El-Sonbati, A.Z.

2000-01-01

Metal complexes of copper(II), nickel(II), cobalt(II) and uranyl ions with 3-(p-tolylsulphonamido)rhodamine (HL) have been prepared and characterized by chemical and thermal analyses, molar conductivity , magnetic susceptibility measurements, and infrared, electronic and EPR spectra. The visible and EPR spectra indicated that the Cu(II) complex has a tetragonal geometry. From EPR spectrum of the Cu(II) complex,various parameters were calculated. The crystal field parameters of Ni(II) complex were calculated and were found to agree fairly well with the values reported for known square pyramidal complexes. The infrared spectral studies showed a monobasic bidentate behaviour with the oxygen and nitrogen donor system. Thermal stabilities of the complexes are also reported. (author)

Complex dynamical invariants for two-dimensional complex potentials

Indian Academy of Sciences (India)

Abstract. Complex dynamical invariants are searched out for two-dimensional complex poten- tials using rationalization method within the framework of an extended complex phase space characterized by x = x1 + ip3, y = x2 + ip4, px = p1 + ix3, py = p2 + ix4. It is found that the cubic oscillator and shifted harmonic oscillator ...

Rotation Invariance Neural Network

OpenAIRE

Li, Shiyuan

2017-01-01

Rotation invariance and translation invariance have great values in image recognition tasks. In this paper, we bring a new architecture in convolutional neural network (CNN) named cyclic convolutional layer to achieve rotation invariance in 2-D symbol recognition. We can also get the position and orientation of the 2-D symbol by the network to achieve detection purpose for multiple non-overlap target. Last but not least, this architecture can achieve one-shot learning in some cases using thos...

Electron-impact coherence parameters for 41 P 1 excitation of zinc

Science.gov (United States)

Piwiński, Mariusz; Kłosowski, Łukasz; Chwirot, Stanisław; Fursa, Dmitry V.; Bray, Igor; Das, Tapasi; Srivastava, Rajesh

2018-04-01

We present electron-impact coherence parameters (EICP) for electron-impact excitation of 41 P 1 state of zinc atoms for collision energies 40 eV and 60 eV. The experimental results are presented together with convergent close-coupling and relativistic distorted-wave approximation theoretical predictions. The results are compared and discussed with EICP data for collision energies 80 eV and 100 eV.

Hidden invariance of the free classical particle

International Nuclear Information System (INIS)

Garcia, S.

1994-01-01

A formalism describing the dynamics of classical and quantum systems from a group theoretical point of view is presented. We apply it to the simple example of the classical free particle. The Galileo group G is the symmetry group of the free equations of motion. Consideration of the free particle Lagrangian semi-invariance under G leads to a larger symmetry group, which is a central extension of the Galileo group by the real numbers. We study the dynamics associated with this group, and characterize quantities like Noether invariants and evolution equations in terms of group geometric objects. An extension of the Galileo group by U(1) leads to quantum mechanics

Complete amino acid sequence of a Lolium perenne (perennial rye grass) pollen allergen, Lol p II.

Science.gov (United States)

Ansari, A A; Shenbagamurthi, P; Marsh, D G

1989-07-05

The complete amino acid sequence of a Lolium perenne (rye grass) pollen allergen, Lol p II was determined by automated Edman degradation of the protein and selected fragments. Cleavage of the protein by enzymatic and chemical techniques established an unambiguous sequence for the protein. Lol p II contains 97 amino acid residues, with a calculated molecular weight of 10,882. The protein lacks cysteine and glutamine and shows no evidence of glycosylation. Theoretical predictions by Fraga's (Fraga, S. (1982) Can. J. Chem. 60, 2606-2610) and Hopp and Woods' (Hopp, T. P., and Woods, K. R. (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 3824-3828) methods indicate the presence of four hydrophilic regions, which may contribute to sequential or parts of conformational B-cell epitopes. Analysis of amphipathic regions by Berzofsky's method indicates the presence of a highly amphipathic region, which may contain, or contribute to, an Ia/T-cell epitope. This latter segment of Lol p II was found to be highly homologous with an antibody-binding segment of the major rye allergen Lol p I and may explain why immune responsiveness to both the allergens is associated with HLA-DR3.

World-line quantization of a reciprocally invariant system

International Nuclear Information System (INIS)

Govaerts, Jan; Jarvis, Peter D; Morgan, Stuart O; Low, Stephen G

2007-01-01

We present the world-line quantization of a system invariant under the symmetries of reciprocal relativity (pseudo-unitary transformations on 'phase-space coordinates' (x μ (τ), p μ (τ)) which preserve the Minkowski metric and the symplectic form, and global shifts in these coordinates, together with coordinate-dependent transformations of an additional compact phase coordinate, θ(τ)). The action is that of free motion over the corresponding Weyl-Heisenberg group. Imposition of the first class constraint, the generator of local time reparametrizations, on physical states enforces identification of the world-line cosmological constant with a fixed value of the quadratic Casimir of the quaplectic symmetry group Q(D-1,1)≅U(D-1,1)xH(D), the semi-direct product of the pseudo-unitary group with the Weyl-Heisenberg group (the central extension of the global translation group, with central extension associated with the phase variable θ(τ)). The spacetime spectrum of physical states is identified. Even though for an appropriate range of values the restriction enforced by the cosmological constant projects out negative norm states from the physical gauge invariant spectrum, leaving over spin zero states only, in this purely bosonic setting the mass-squared spectrum is continuous over the entire real line and thus includes a tachyonic branch as well

Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient mice

DEFF Research Database (Denmark)

Holst, Peter Johannes; Christensen, Jan Pravsgaard; Thomsen, Allan Randrup

2011-01-01

response could be elicited in MHC class II-deficient mice by vaccination with adenovirus encoding lymphocytic choriomeningitis virus (LCMV) glycoprotein tethered to MHC class II-associated invariant chain. Moreover, the response induced conferred significant cytolytic CD8(+) T cell-mediated protection...... against challenge with a high dose of the invasive clone 13 strain of LCMV. In contrast, vaccination with adenovirus encoding unlinked LCMV glycoprotein induced weak virus control in the absence of CD4(+) T cells, and mice may die of increased immunopathology associated with incomplete protection. Acute...... mortality was not observed in any vaccinated mice following infection with the less-invasive Traub strain. However, LCMV Traub infection caused accelerated late mortality in unvaccinated MHC class II-deficient mice; in this case, we observed a strong trend toward delayed mortality in vaccinated mice...

Using impulses to control the convergence toward invariant surfaces of continuous dynamical systems

International Nuclear Information System (INIS)

Marão, José; Liu Xinzhi; Figueiredo, Annibal

2012-01-01

Let us consider a smooth invariant surface S of a given ordinary differential equations system. In this work we develop an impulsive control method in order to assure that the trajectories of the controlled system converge toward the surface S. The method approach is based on a property of a certain class of invariant surfaces whose the dynamics associated to their transverse directions can be described by a non-autonomous linear system. This fact allows to define an impulsive system which drives the trajectories toward the surface S. Also, we set up a definition of local stability exponents which can be associated to such kind of invariant surface.

The Dynamical Invariant of Open Quantum System

OpenAIRE

Wu, S. L.; Zhang, X. Y.; Yi, X. X.

2015-01-01

The dynamical invariant, whose expectation value is constant, is generalized to open quantum system. The evolution equation of dynamical invariant (the dynamical invariant condition) is presented for Markovian dynamics. Different with the dynamical invariant for the closed quantum system, the evolution of the dynamical invariant for the open quantum system is no longer unitary, and the eigenvalues of it are time-dependent. Since any hermitian operator fulfilling dynamical invariant condition ...

Synthesizing Modular Invariants for Synchronous Code

Directory of Open Access Journals (Sweden)

Pierre-Loic Garoche

2014-12-01

Full Text Available In this paper, we explore different techniques to synthesize modular invariants for synchronous code encoded as Horn clauses. Modular invariants are a set of formulas that characterizes the validity of predicates. They are very useful for different aspects of analysis, synthesis, testing and program transformation. We describe two techniques to generate modular invariants for code written in the synchronous dataflow language Lustre. The first technique directly encodes the synchronous code in a modular fashion. While in the second technique, we synthesize modular invariants starting from a monolithic invariant. Both techniques, take advantage of analysis techniques based on property-directed reachability. We also describe a technique to minimize the synthesized invariants.

Four-dimensional symmetry from a broad viewpoint. II Invariant distribution of quantized field oscillators and questions on infinities

Science.gov (United States)

Hsu, J. P.

1983-01-01

The foundation of the quantum field theory is changed by introducing a new universal probability principle into field operators: one single inherent and invariant probability distribution P(/k/) is postulated for boson and fermion field oscillators. This can be accomplished only when one treats the four-dimensional symmetry from a broad viewpoint. Special relativity is too restrictive to allow such a universal probability principle. A radical length, R, appears in physics through the probability distribution P(/k/). The force between two point particles vanishes when their relative distance tends to zero. This appears to be a general property for all forces and resembles the property of asymptotic freedom. The usual infinities in vacuum fluctuations and in local interactions, however complicated they may be, are all removed from quantum field theories. In appendix A a simple finite and unitary theory of unified electroweak interactions is discussed without assuming Higgs scalar bosons.

Hidden scale invariance of metals

DEFF Research Database (Denmark)

Hummel, Felix; Kresse, Georg; Dyre, Jeppe C.

2015-01-01

Density functional theory (DFT) calculations of 58 liquid elements at their triple point show that most metals exhibit near proportionality between the thermal fluctuations of the virial and the potential energy in the isochoric ensemble. This demonstrates a general “hidden” scale invariance...... of metals making the condensed part of the thermodynamic phase diagram effectively one dimensional with respect to structure and dynamics. DFT computed density scaling exponents, related to the Grüneisen parameter, are in good agreement with experimental values for the 16 elements where reliable data were...... available. Hidden scale invariance is demonstrated in detail for magnesium by showing invariance of structure and dynamics. Computed melting curves of period three metals follow curves with invariance (isomorphs). The experimental structure factor of magnesium is predicted by assuming scale invariant...

Invariance for Single Curved Manifold

KAUST Repository

Castro, Pedro Machado Manhaes de

2012-01-01

Recently, it has been shown that, for Lambert illumination model, solely scenes composed by developable objects with a very particular albedo distribution produce an (2D) image with isolines that are (almost) invariant to light direction change. In this work, we provide and investigate a more general framework, and we show that, in general, the requirement for such in variances is quite strong, and is related to the differential geometry of the objects. More precisely, it is proved that single curved manifolds, i.e., manifolds such that at each point there is at most one principal curvature direction, produce invariant is surfaces for a certain relevant family of energy functions. In the three-dimensional case, the associated energy function corresponds to the classical Lambert illumination model with albedo. This result is also extended for finite-dimensional scenes composed by single curved objects. © 2012 IEEE.

Invariance for Single Curved Manifold

KAUST Repository

Castro, Pedro Machado Manhaes de

2012-08-01

Recently, it has been shown that, for Lambert illumination model, solely scenes composed by developable objects with a very particular albedo distribution produce an (2D) image with isolines that are (almost) invariant to light direction change. In this work, we provide and investigate a more general framework, and we show that, in general, the requirement for such in variances is quite strong, and is related to the differential geometry of the objects. More precisely, it is proved that single curved manifolds, i.e., manifolds such that at each point there is at most one principal curvature direction, produce invariant is surfaces for a certain relevant family of energy functions. In the three-dimensional case, the associated energy function corresponds to the classical Lambert illumination model with albedo. This result is also extended for finite-dimensional scenes composed by single curved objects. © 2012 IEEE.

Reducing Lookups for Invariant Checking

DEFF Research Database (Denmark)

Thomsen, Jakob Grauenkjær; Clausen, Christian; Andersen, Kristoffer Just

2013-01-01

This paper helps reduce the cost of invariant checking in cases where access to data is expensive. Assume that a set of variables satisfy a given invariant and a request is received to update a subset of them. We reduce the set of variables to inspect, in order to verify that the invariant is still...

Biosorption of Cd(II) and Zn(II) by nostoc commune: isotherm and kinetics studies

Energy Technology Data Exchange (ETDEWEB)

Morsy, Fatthy M. [Faculty of Science, Botany Department, Assiut University, Assiut (Egypt); Hassan, Sedky H.A. [Department of Biological Environment, Kangwon National University, Kangwon-do (Korea, Republic of); Koutb, Mostafa [Faculty of Science, Botany Department, Assiut University, Assiut (Egypt); Umm Al-Qura University, Faculty of Applied Science, Biology Department, Mecca (Saudi Arabia)

2011-07-15

In this study, Nostoc commune (cyanobacterium) was used as an inexpensive and efficient biosorbent for Cd(II) and Zn(II) removal from aqueous solutions. The effect of various physicochemical factors on Cd(II) and Zn(II) biosorption such as pH 2.0-7.0, initial metal concentration 0.0-300 mg/L and contact time 0-120 min were studied. Optimum pH for removal of Cd(II) and Zn(II) was 6.0, while the contact time was 30 min at room temperature. The nature of biosorbent and metal ion interaction was evaluated by infrared (IR) technique. IR analysis of bacterial biomass revealed the presence of amino, carboxyl, hydroxyl, and carbonyl groups, which are responsible for biosorption of Cd(II) and Zn (II). The maximum biosorption capacities for Cd(II) and Zn(II) biosorption by N. commune calculated from Langmuir biosorption isotherm were 126.32 and 115.41 mg/g, respectively. The biosorption isotherm for two biosorbents fitted well with Freundlich isotherm than Langmuir model with correlation coefficient (r{sup 2} < 0.99). The biosorption kinetic data were fitted well with the pseudo-second-order kinetic model. Thus, this study indicated that the N. commune is an efficient biosorbent for the removal of Cd(II) and Zn(II) from aqueous solutions. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

Algorithms in invariant theory

CERN Document Server

Sturmfels, Bernd

2008-01-01

J. Kung and G.-C. Rota, in their 1984 paper, write: "Like the Arabian phoenix rising out of its ashes, the theory of invariants, pronounced dead at the turn of the century, is once again at the forefront of mathematics". The book of Sturmfels is both an easy-to-read textbook for invariant theory and a challenging research monograph that introduces a new approach to the algorithmic side of invariant theory. The Groebner bases method is the main tool by which the central problems in invariant theory become amenable to algorithmic solutions. Students will find the book an easy introduction to this "classical and new" area of mathematics. Researchers in mathematics, symbolic computation, and computer science will get access to a wealth of research ideas, hints for applications, outlines and details of algorithms, worked out examples, and research problems.

Vaccination with an adenoviral vector encoding the tumor antigen directly linked to invariant chain induces potent CD4(+) T-cell-independent CD8(+) T-cell-mediated tumor control

DEFF Research Database (Denmark)

Sorensen, Maria R; Holst, Peter J; Pircher, Hanspeter

2009-01-01

of the vaccine antigen to invariant chain (Ii). To evaluate this strategy we used a mouse model, in which an immunodominant epitope (GP33) of the LCMV glycoprotein (GP) represents the tumor-associated neoantigen. Prophylactic vaccination of C57BL/6 mice with a replication-deficient human adenovirus 5 vector...... encoding GP linked to Ii (Ad-Ii-GP) resulted in complete protection against GP33-expressing B16.F10 tumors. Therapeutic vaccination with Ad-Ii-GP delayed tumor growth by more than 2 wk compared with sham vaccination. Notably, therapeutic vaccination with the linked vaccine was significantly better than...... the tumor degradation. Finally, Ad-Ii-GP but not Ad-GP vaccination can break the immunological non-reactivity in GP transgenic mice indicating that our vaccine strategy will prove efficient also against endogenous tumor antigens....

Copy number variations of chromosome 16p13.1 region associated with schizophrenia

DEFF Research Database (Denmark)

Ingason, A; Rujescu, D; Cichon, S

2011-01-01

.007) and deletions in 0.12 % of cases and 0.04% of controls (P>0.05). The region can be divided into three intervals defined by flanking low copy repeats. Duplications spanning intervals I and II showed the most significant (P = 0.00010) association with schizophrenia. The age of onset in duplication and deletion...... carriers among cases ranged from 12 to 35 years, and the majority were males with a family history of psychiatric disorders. In a single Icelandic family, a duplication spanning intervals I and II was present in two cases of schizophrenia, and individual cases of alcoholism, attention deficit hyperactivity...

Pomeron-Quark Coupling from Charge Conjugation Invariance

International Nuclear Information System (INIS)

Zhou Lijuan; Wu Qing; Ma Weixing; Gu Yunting

2006-01-01

Based on the charge conjugation invariance and the vacuum property of the Pomeron, we point out that the commonly used vector vertex of the Pomeron coupling to quark is incorrect since it contradicts with the Pomeron property. We also claim that the soft Pomeron could be a tensor glueball ξ(2230) with quantum numbers I G J PC = 0 + 2 ++ and total decay width Γ tot ≅100 MeV, which lies on the soft Pomeron trajectory α p = 1.08+0.20t. Therefore, the coupling vertex of the soft Pomeron to quark should be tensorial which is invariant under the charge conjugation and can explain why the inadequate vector coupling, γ μ , of the soft Pomeron to quark is successful in dealing with Pomeron physics.

Cartan invariants and event horizon detection

Science.gov (United States)

Brooks, D.; Chavy-Waddy, P. C.; Coley, A. A.; Forget, A.; Gregoris, D.; MacCallum, M. A. H.; McNutt, D. D.

2018-04-01

We show that it is possible to locate the event horizon of a black hole (in arbitrary dimensions) by the zeros of certain Cartan invariants. This approach accounts for the recent results on the detection of stationary horizons using scalar polynomial curvature invariants, and improves upon them since the proposed method is computationally less expensive. As an application, we produce Cartan invariants that locate the event horizons for various exact four-dimensional and five-dimensional stationary, asymptotically flat (or (anti) de Sitter), black hole solutions and compare the Cartan invariants with the corresponding scalar curvature invariants that detect the event horizon.

Blind phase retrieval for aberrated linear shift-invariant imaging systems

International Nuclear Information System (INIS)

Yu, Rotha P; Paganin, David M

2010-01-01

We develop a means to reconstruct an input complex coherent scalar wavefield, given a through focal series (TFS) of three intensity images output from a two-dimensional (2D) linear shift-invariant optical imaging system with unknown aberrations. This blind phase retrieval technique unites two methods, namely (i) TFS phase retrieval and (ii) iterative blind deconvolution. The efficacy of our blind phase retrieval procedure has been demonstrated using simulated data, for a variety of Poisson noise levels.

Modulation of radiation injury response in retinal endothelial cells by quinic acid derivative KZ-41 involves p38 MAPK.

Directory of Open Access Journals (Sweden)

Jordan J Toutounchian

Full Text Available Radiation-induced damage to the retina triggers leukostasis, retinal endothelial cell (REC death, and subsequent hypoxia. Resultant ischemia leads to visual loss and compensatory retinal neovascularization (RNV. Using human RECs, we demonstrated that radiation induced leukocyte adhesion through mechanisms involving p38MAPK, p53, and ICAM-1 activation. Additional phenotypic changes included p38MAPK-dependent tyrosine phosphorylation of the focal adhesion scaffolding protein, paxillin (Tyr118. The quinic acid derivative KZ-41 lessened leukocyte adhesion and paxillin-dependent proliferation via inhibition of p38MAPK-p53-ICAM-1 signaling. Using the murine oxygen-induced retinopathy (OIR model, we examined the effect of KZ-41 on pathologic RNV. Daily ocular application of a KZ-41-loaded nanoemulsion significantly reduced both the avascular and neovascular areas in harvested retinal flat mounts when compared to the contralateral eye receiving vehicle alone. Our data highlight the potential benefit of KZ-41 in reducing both the retinal ischemia and neovascularization provoked by genotoxic insults. Further research into how quinic acid derivatives target and mitigate inflammation is needed to fully appreciate their therapeutic potential for the treatment of inflammatory retinal vasculopathies.

Mass generation within conformal invariant theories

International Nuclear Information System (INIS)

Flato, M.; Guenin, M.

1981-01-01

The massless Yang-Mills theory is strongly conformally invariant and renormalizable; however, when masses are introduced the theory becomes nonrenormalizable and weakly conformally invariant. Conditions which recover strong conformal invariance are discussed in the letter. (author)

Refined algebraic quantisation in a system with nonconstant gauge invariant structure functions

International Nuclear Information System (INIS)

Martínez-Pascual, Eric

2013-01-01

In a previous work [J. Louko and E. Martínez-Pascual, “Constraint rescaling in refined algebraic quantisation: Momentum constraint,” J. Math. Phys. 52, 123504 (2011)], refined algebraic quantisation (RAQ) within a family of classically equivalent constrained Hamiltonian systems that are related to each other by rescaling one momentum-type constraint was investigated. In the present work, the first steps to generalise this analysis to cases where more constraints occur are developed. The system under consideration contains two momentum-type constraints, originally abelian, where rescalings of these constraints by a non-vanishing function of the coordinates are allowed. These rescalings induce structure functions at the level of the gauge algebra. Providing a specific parametrised family of real-valued scaling functions, the implementation of the corresponding rescaled quantum momentum-type constraints is performed using RAQ when the gauge algebra: (i) remains abelian and (ii) undergoes into an algebra of a nonunimodular group with nonconstant gauge invariant structure functions. Case (ii) becomes the first example known to the author where an open algebra is handled in refined algebraic quantisation. Challenging issues that arise in the presence of non-gauge invariant structure functions are also addressed

Coordinate-invariant regularization

International Nuclear Information System (INIS)

Halpern, M.B.

1987-01-01

A general phase-space framework for coordinate-invariant regularization is given. The development is geometric, with all regularization contained in regularized DeWitt Superstructures on field deformations. Parallel development of invariant coordinate-space regularization is obtained by regularized functional integration of the momenta. As representative examples of the general formulation, the regularized general non-linear sigma model and regularized quantum gravity are discussed. copyright 1987 Academic Press, Inc

Invariant sets for Windows

CERN Document Server

Morozov, Albert D; Dragunov, Timothy N; Malysheva, Olga V

1999-01-01

This book deals with the visualization and exploration of invariant sets (fractals, strange attractors, resonance structures, patterns etc.) for various kinds of nonlinear dynamical systems. The authors have created a special Windows 95 application called WInSet, which allows one to visualize the invariant sets. A WInSet installation disk is enclosed with the book.The book consists of two parts. Part I contains a description of WInSet and a list of the built-in invariant sets which can be plotted using the program. This part is intended for a wide audience with interests ranging from dynamical

Measurements and calculations for determination of discharge of 41Ar from IFEs research reactor JEEP II at Kjeller, Norway

International Nuclear Information System (INIS)

Raaum, A.; Straelberg, E.

2003-01-01

41 Ar is formed by neutron irradiation of 40 Ar, which occurs naturally in air with a concentration of 9300 ppm. The discharge of 41 Ar from IFEs research reactor Jeep II is yearly reported to the Norwegian Radiation Protection Authority (NRPA). Until year 2000 the reported values were based on theoretical calculations of produced 41 Ar per operating hour of 6.8 GBq/h. During 2000 and 2001 the reactor was upgraded to increase the irradiation capacity and to meet the markets demand for irradiation of 5'Si-crystalls. After the upgrading, measurements and calculations were initiated to determine the new discharge rate for 41 Ar. During reactor operation an approximately constant discharge of 41 Ar is expected, mainly due to irradiation of air in open beam channels. In addition 41 Ar is released from irradiation pockets when they are opened to transfer samples in and out during reactor stop. The new value for discharge rate was determined from measurements of air samples from the discharge channel during operation and theoretical calculations of the release from the irradiation pockets. The new discharge rate was determined to 5.9 ± 0.5 GBq/h, which is a small reduction compared to the former value of 6.8 GBq/h. A small reduction in discharge rate was expected because the number of air-filled irradiation pockets was reduced after the upgrading. In a normal year the discharge of 41 Ar will be about 2 % of the Institutes discharge permission. (orig.)

Invariant strings and pattern-recognizing properties of one-dimensional cellular automata

International Nuclear Information System (INIS)

Jen, E.

1986-01-01

A cellular automaton is a discrete dynamical system whose evolution is governed by a deterministic rule involving local interactions. It is shown that given an arbitrary string of values and an arbitry neighborhood size (representing the range of interaction), a simple procedure can be used to find the fules of that neighborhood size under which the string is unvarian. The set of nearestneighbor rules for which invariant strings exist is completely specified, as is the set of strings invariant under each such rule. For any automaton rule, an associated ''filtering'' rule is defined for which the only attractors are spatial sequences consisting of concatenations of invariant strings. A result is provided defining the rule of minimum neighborhood size for which an arbitrrily chosen string is the unique invariant string. The applications of filtering rules to pttern recognition problems are discussed

Moment forms invariant to rotation and blur in arbitrary number of dimensions

Czech Academy of Sciences Publication Activity Database

Flusser, Jan; Boldyš, Jiří; Zitová, Barbara

2003-01-01

Roč. 25, č. 2 (2003), s. 234-246 ISSN 0162-8828 R&D Projects: GA ČR GA102/00/1711; GA ČR GP102/01/P065 Institutional research plan: CEZ:AV0Z1075907 Keywords : blur invariants * rotation invariants * group representation theory Subject RIV: JD - Computer Applications, Robotics Impact factor: 3.823, year: 2003 http://library.utia.cas.cz/prace/20030006.pdf

14 CFR 1273.41 - Financial reporting.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Financial reporting. 1273.41 Section 1273... Reports, Records, Retention, and Enforcement § 1273.41 Financial reporting. (a) General. (1) Except as... authorized by OMB, for: (i) Submitting financial reports to Federal agencies, or (ii) Requesting advances or...

13 CFR 143.41 - Financial reporting.

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Financial reporting. 143.41... Reports, Records, Retention, and Enforcement § 143.41 Financial reporting. (a) General. (1) Except as... authorized by OMB, for: (i) Submitting financial reports to Federal agencies, or (ii) Requesting advances or...

Associations among Gastric Juice pH, Atrophic Gastritis, Intestinal Metaplasia and Helicobacter pylori Infection

Science.gov (United States)

Sung, Jihee; Lee, Jongchan; Hwang, Young-Jae; Kim, Hyoung Woo; Chung, Jung Wha; Kim, Jin-Wook; Lee, Dong Ho

2018-01-01

Background/Aims Gastric juice plays a crucial role in the physiology of the stomach. The aim of this study is to evaluate associations among the pH of gastric juice, atrophic gastritis (AG), intestinal metaplasia (IM), pepsinogen, and Helicobacter pylori infection. Methods Gastric biopsies and juice were collected from 46 subjects who underwent endoscopies at Seoul National University Bundang Hospital between November 2011 and March 2013. H. pylori, AG and IM were evaluated, and pepsinogen I or II, I/II ratio, and interleukin (IL)-1β levels were measured. Results The mean pH of gastric juice was higher in the H. pylori-positive group (n=17) than that in the H. pylori-negative group (n=29) (4.54 vs 2.46, p=0.002). When patients were divided into pH <3 (n=28) and pH ≥3 (n=18) groups, H. pylori was lower in the pH <3 group (21.4%) than in the pH ≥3 group (61.1%) (p=0.007). The pH ≥3 group demonstrated AG and IM more frequently than the pH <3 group in the body (p=0.047 and p=0.051, respectively) but not in the antrum. There were no differences in pepsinogen I or II, I/II ratio, and IL-1β levels between the two groups. Conclusions There is a relationship between chronic H. pylori infection and gastric juice pH ≥3, which may originate from AG and IM in the body. PMID:28918609

Associations among Gastric Juice pH, Atrophic Gastritis, Intestinal Metaplasia and Helicobacter pylori Infection.

Science.gov (United States)

Sung, Jihee; Kim, Nayoung; Lee, Jongchan; Hwang, Young-Jae; Kim, Hyoung Woo; Chung, Jung Wha; Kim, Jin-Wook; Lee, Dong Ho

2018-03-15

Gastric juice plays a crucial role in the physiology of the stomach. The aim of this study is to evaluate associations among the pH of gastric juice, atrophic gastritis (AG), intestinal metaplasia (IM), pepsinogen, and Helicobacter pylori infection. Gastric biopsies and juice were collected from 46 subjects who underwent endoscopies at Seoul National University Bundang Hospital between November 2011 and March 2013. H. pylori , AG and IM were evaluated, and pepsinogen I or II, I/II ratio, and interleukin (IL)-1β levels were measured. The mean pH of gastric juice was higher in the H. pylori -positive group (n=17) than that in the H. pylori -negative group (n=29) (4.54 vs 2.46, p=0.002). When patients were divided into pH ＜3 (n=28) and pH ≥3 (n=18) groups, H. pylori was lower in the pH ＜3 group (21.4%) than in the pH ≥3 group (61.1%) (p=0.007). The pH ≥3 group demonstrated AG and IM more frequently than the pH ＜3 group in the body (p=0.047 and p=0.051, respectively) but not in the antrum. There were no differences in pepsinogen I or II, I/II ratio, and IL-1β levels between the two groups. There is a relationship between chronic H. pylori infection and gastric juice pH ≥3, which may originate from AG and IM in the body.

Copper(II) complexes with 4-(1H-1, 2, 4-trizol-1-ylmethyl) benzoic acid: Syntheses, crystal structures and antifungal activities

International Nuclear Information System (INIS)

Xiong, Pingping; Li, Jie; Bu, Huaiyu; Wei, Qing; Zhang, Ruolin; Chen, Sanping

2014-01-01

Reaction of Cu(II) with an asymmetric semi-rigid organic ligand 4-(1H-1, 2, 4-trizol-1-ylmethyl) benzoic acid (HL), yielded five compounds, [Cu 0.5 L] n (1), [Cu(HL) 2 Cl 2 ] n (2), [Cu(HL) 2 Cl 2 (H 2 O)] (3), [Cu(L) 2 (H 2 O)] n (4) and [Cu(L)(phen)(HCO 2 )] n (5), which have been fully characterized by infrared spectroscopy, elemental analysis, and single-crystal X-ray diffraction. As for compounds 1, 2 and 5, Cu(II) is bridged through HL, Cl - , and formic acid, respectively, featuring 1D chain-structure. In compound 3, Cu(II) with hexahedral coordination sphere is assembled through hydrogen-bonding into 3D supramolecular framework. In compound 4, 1D chain units –Cu–O–Cu–O– are ligand-bridged into a 3D network. All compounds were tested on fungi (Fusarium graminearum, Altemaria solani, Macrophoma kawatsukai, Alternaria alternata and Colletotrichum gloeosporioides). Compound 1 exhibits a better antifungal effect compared to other compounds. An effect of structure on the antifungal activity has also been correlated. - Graphical abstract: Copper(II) compounds with 4-(1H-1, 2, 4-trizol-1-ylmethyl) benzoic acid, were prepared, structurally characterized and investigated for antifungal activity. - Highlights: • The title compounds formed by thermodynamics and thermokinetics. • The five compounds show higher inhibition percentage than reactants. • The structure effect on the antifungal activity

Invariant Set Theory: Violating Measurement Independence without Fine Tuning, Conspiracy, Constraints on Free Will or Retrocausality

Directory of Open Access Journals (Sweden)

Tim Palmer

2015-11-01

Full Text Available Invariant Set (IS theory is a locally causal ontic theory of physics based on the Cosmological Invariant Set postulate that the universe U can be considered a deterministic dynamical system evolving precisely on a (suitably constructed fractal dynamically invariant set in U's state space. IS theory violates the Bell inequalities by violating Measurement Independence. Despite this, IS theory is not fine tuned, is not conspiratorial, does not constrain experimenter free will and does not invoke retrocausality. The reasons behind these claims are discussed in this paper. These arise from properties not found in conventional ontic models: the invariant set has zero measure in its Euclidean embedding space, has Cantor Set structure homeomorphic to the p-adic integers (p>>0 and is non-computable. In particular, it is shown that the p-adic metric encapulates the physics of the Cosmological Invariant Set postulate, and provides the technical means to demonstrate no fine tuning or conspiracy. Quantum theory can be viewed as the singular limit of IS theory when when p is set equal to infinity. Since it is based around a top-down constraint from cosmology, IS theory suggests that gravitational and quantum physics will be unified by a gravitational theory of the quantum, rather than a quantum theory of gravity. Some implications arising from such a perspective are discussed.

What's hampering measurement invariance : Detecting non-invariant items using clusterwise simultaneous component analysis

NARCIS (Netherlands)

De Roover, K.; Timmerman, Marieke; De Leersnyder, J.; Mesquita, B.; Ceulemans, Eva

2014-01-01

The issue of measurement invariance is ubiquitous in the behavioral sciences nowadays as more and more studies yield multivariate multigroup data. When measurement invariance cannot be established across groups, this is often due to different loadings on only a few items. Within the multigroup CFA

Average [O II] nebular emission associated with Mg II absorbers: dependence on Fe II absorption

Science.gov (United States)

Joshi, Ravi; Srianand, Raghunathan; Petitjean, Patrick; Noterdaeme, Pasquier

2018-05-01

We investigate the effect of Fe II equivalent width (W2600) and fibre size on the average luminosity of [O II] λλ3727, 3729 nebular emission associated with Mg II absorbers (at 0.55 ≤ z ≤ 1.3) in the composite spectra of quasars obtained with 3 and 2 arcsec fibres in the Sloan Digital Sky Survey. We confirm the presence of strong correlations between [O II] luminosity (L_{[O II]}) and equivalent width (W2796) and redshift of Mg II absorbers. However, we show L_{[O II]} and average luminosity surface density suffer from fibre size effects. More importantly, for a given fibre size, the average L_{[O II]} strongly depends on the equivalent width of Fe II absorption lines and found to be higher for Mg II absorbers with R ≡W2600/W2796 ≥ 0.5. In fact, we show the observed strong correlations of L_{[O II]} with W2796 and z of Mg II absorbers are mainly driven by such systems. Direct [O II] detections also confirm the link between L_{[O II]} and R. Therefore, one has to pay attention to the fibre losses and dependence of redshift evolution of Mg II absorbers on W2600 before using them as a luminosity unbiased probe of global star formation rate density. We show that the [O II] nebular emission detected in the stacked spectrum is not dominated by few direct detections (i.e. detections ≥3σ significant level). On an average, the systems with R ≥ 0.5 and W2796 ≥ 2 Å are more reddened, showing colour excess E(B - V) ˜ 0.02, with respect to the systems with R < 0.5 and most likely trace the high H I column density systems.

Identification of two novel critical mutations in PCNT gene resulting in microcephalic osteodysplastic primordial dwarfism type II associated with multiple intracranial aneurysms.

Science.gov (United States)

Li, Fei-Feng; Wang, Xu-Dong; Zhu, Min-Wei; Lou, Zhi-Hong; Zhang, Qiong; Zhu, Chun-Yu; Feng, Hong-Lin; Lin, Zhi-Guo; Liu, Shu-Lin

2015-12-01

Microcephalic osteodysplastic primordial dwarfism type II (MOPD II) is a highly detrimental human autosomal inherited recessive disorder. The hallmark characteristics of this disease are intrauterine and postnatal growth restrictions, with some patients also having cerebrovascular problems such as cerebral aneurysms. The genomic basis behind most clinical features of MOPD II remains largely unclear. The aim of this work was to identify the genetic defects in a Chinese family with MOPD II associated with multiple intracranial aneurysms. The patient had typical MOPD II syndrome, with subarachnoid hemorrhage and multiple intracranial aneurysms. We identified three novel mutations in the PCNT gene, including one single base alteration (9842A>C in exon 45) and two deletions (Del-C in exon 30 and Del-16 in exon 41). The deletions were co-segregated with the affected individual in the family and were not present in the control population. Computer modeling demonstrated that the deletions may cause drastic changes on the secondary and tertiary structures, affecting the hydrophilicity and hydrophobicity of the mutant proteins. In conclusion, we identified two novel mutations in the PCNT gene associated with MOPD II and intracranial aneurysms, and the mutations were expected to alter the stability and functioning of the protein by computer modeling.

Topological entropy for finite invariant sets of Y

International Nuclear Information System (INIS)

Li Shihai; Ye Xiangdong.

1992-12-01

Let Y be the space {z is an element of C:z 3 is an element of [0,1]} with a metric defined by the arc length. Suppose that f is an element of C(Y,Y) and P is a finite f-invariant set. The topological entropy of (P,f), h(P), is the infimum of the topological entropies of maps from C(Y,Y) which agree with f on P. In this paper we construct a function C P is an element of C(Y,Y) satisfying C P | P =f| P which achieves the topological entropy of (P,f). (author). 14 refs

Search for new physics using high mass tau pairs with ppbar collisions at 1.96 Tev using cdf ii

International Nuclear Information System (INIS)

Acosta, D.; The CDF Collaboration

2005-01-01

We present the results of a search for anomalous resonant production of tau lepton pairs with large invariant mass, the first such search using the CDF II Detector in Run II of the Tevatron p(bar p) collider. Such anomalous production could arise from various new physics processes. In a data sample corresponding to 195 pb -1 of integrated luminosity we predict 2.8 ± 0.5 events from Standard Model background processes and observe 4. We use this result to set limits on the production of heavy scalar and vector particles decaying to tau lepton pairs

Type II NKT Cells and Their Emerging Role in Health and Disease.

Science.gov (United States)

Dhodapkar, Madhav V; Kumar, Vipin

2017-02-01

NKT cells recognize lipid Ags presented by a class I MHC-like molecule CD1d, a member of the CD1 family. Although most initial studies on NKT cells focused on a subset with semi-invariant TCR termed invariant NKT cells, the majority of CD1d-restricted lipid-reactive human T cells express diverse TCRs and are termed type II NKT cells. These cells constitute a distinct population of circulating and tissue-resident effector T cells with immune-regulatory properties. They react to a growing list of self- as well as non-self-lipid ligands, and share some properties with both invariant NKT and conventional T cells. An emerging body of evidence points to their role in the regulation of immunity to pathogens/tumors and in autoimmune/metabolic disorders. An improved understanding of the biology of these cells and the ability to manipulate their function may be of therapeutic benefit in diverse disease conditions. Copyright © 2017 by The American Association of Immunologists, Inc.

Precision lifetime measurements of Ar II 4p doublet levels

International Nuclear Information System (INIS)

Marger, D.; Schmoranzer, H.

1990-01-01

The lifetimes of the Ar II 4p doublet fine-structure levels 4p 2 D 0 5/2 , 4p' 2 F 0 5/2 and 4p' 2 F 0 7/2 were measured by beam-dye laser spectroscopy. The experimental uncertainty was reduced to below 1%. (orig.)

Adiabatic invariance with first integrals of motion

Science.gov (United States)

Adib, Artur B.

2002-10-01

The construction of a microthermodynamic formalism for isolated systems based on the concept of adiabatic invariance is an old but seldom appreciated effort in the literature, dating back at least to P. Hertz [Ann. Phys. (Leipzig) 33, 225 (1910)]. An apparently independent extension of such formalism for systems bearing additional first integrals of motion was recently proposed by Hans H. Rugh [Phys. Rev. E 64, 055101 (2001)], establishing the concept of adiabatic invariance even in such singular cases. After some remarks in connection with the formalism pioneered by Hertz, it will be suggested that such an extension can incidentally explain the success of a dynamical method for computing the entropy of classical interacting fluids, at least in some potential applications where the presence of additional first integrals cannot be ignored.

Differential association of the N-propeptide of collagen IIA (PIIANP) and collagen II C-telopeptide (CTX-II) with synovitis and erosions in early and longstanding rheumatoid arthritis

DEFF Research Database (Denmark)

Christensen, A F; Lottenburger, T; Lindegaard, H

2009-01-01

OBJECTIVES: To determine the N-terminal propeptide of collagen IIA (PIIANP) in early and established rheumatoid arthritis (RA) and to study the association with collagen II degradation assessed by its C-telopeptide (CTX-II), x-ray status and disease activity measures. METHODS: Two cohorts of RA......-ray progression (p=0.84). There was no correlation between PIIANP and CTX-II. CONCLUSION: Declining PIIANP with increasing RA duration and persistently increased CTX-II indicate that cartilage anabolic and degradative pathways are unbalanced from clinical RA onset. Furthermore, that collagen II depletion in RA...... is both mediated by anti-anabolic effects unassociated with synovitis (decreased PIIANP) and by excess collagen II degradation linked to synovitis (increased CTX-II)....

15 CFR 24.41 - Financial reporting.

Science.gov (United States)

2010-01-01

... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Financial reporting. 24.41 Section 24..., Records, Retention, and Enforcement § 24.41 Financial reporting. (a) General. (1) Except as provided in... by OMB, for: (i) Submitting financial reports to Federal agencies, or (ii) Requesting advances or...

DU and UD-invariants of unitary groups

International Nuclear Information System (INIS)

Aguilera-Navarro, M.C.K.

1977-01-01

Four distint ways of obtaining the eigenvalues of unitary groups, in any irreducible representation, are presented. The invariants are defined according to two different contraction conventions. Their eigenvalue can be given in terms of two classes of special partial hooks associated with the young diagram characterizing the irreducible representation considered

Complete primary structure of a Lolium perenne (perennial rye grass) pollen allergen, Lol p III: comparison with known Lol p I and II sequences.

Science.gov (United States)

Ansari, A A; Shenbagamurthi, P; Marsh, D G

1989-10-17

The complete amino acid sequence of a Lolium perenne (rye grass) pollen allergen, Lol p III, determined by the automated Edman degradation of the protein and its selected fragments, is reported in this paper. Cleavage by enzymatic and chemical techniques established unambiguously the sequence for this 97-residue protein (Mr = 10,909), which lacks cysteine and shows no evidence of glycosylation. The sequence of Lol p III is very similar to that of another L. perenne allergen, Lol p II, which was sequenced recently; of the 97 positions in the two proteins, 57 are occupied by identical amino acids (59% identity). In addition, both allergens share a similar structure with an antibody-binding fragment of a third L. perenne allergen, Lol p I. Since human antibody responsiveness to all these three allergens is associated with HLA-DR3, and since the structure common to the three molecules shows high degrees of amphipathicity in Lol p II and III, we speculate that this common segment in the three molecules might contain or contribute to the respectively Ia/T-cell sites.

What’s hampering measurement invariance: Detecting non-invariant items using clusterwise simultaneous component analysis

Directory of Open Access Journals (Sweden)

Kim eDe Roover

2014-06-01

Full Text Available The issue of measurement invariance is ubiquitous in the behavioral sciences nowadays as more and more studies yield multivariate multigroup data. When measurement invariance cannot be established across groups, this is often due to different loadings on only a few items. Within the multigroup CFA framework, methods have been proposed to trace such non-invariant items, but these methods have some disadvantages in that they require researchers to run a multitude of analyses and in that they imply assumptions that are often questionable. In this paper, we propose an alternative strategy which builds on clusterwise simultaneous component analysis (SCA. Clusterwise SCA, being an exploratory technique, assigns the groups under study to a few clusters based on differences and similarities in the covariance matrices, and thus based on the component structure of the items. Non-invariant items can then be traced by comparing the cluster-specific component loadings via congruence coefficients, which is far more parsimonious than comparing the component structure of all separate groups. In this paper we present a heuristic for this procedure. Afterwards, one can return to the multigroup CFA framework and check whether removing the non-invariant items or removing some of the equality restrictions for these items, yields satisfactory invariance test results. An empirical application concerning cross-cultural emotion data is used to demonstrate that this novel approach is useful and can co-exist with the traditional CFA approaches.

Fusion of a viral antigen to invariant chain leads to augmented T-cell immunity and improved protection in gene-gun DNA-vaccinated mice

DEFF Research Database (Denmark)

Grujic, Mirjana; Holst, Peter J; Christensen, Jan P

2009-01-01

It has recently been demonstrated that a recombinant replication-deficient human adenovirus 5 (Ad5) vector expressing lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP) fused to the p31 invariant (Ii) chain confers broad, long-lasting T-cell immunity that completely protects C57BL/6 mice...... with the unlinked construct. In contrast, substantial protection against peripheral challenge was not observed. Additional experiments with T-cell subset-depleted or perforin-deficient mice revealed that virus control in vaccinated mice depends critically on cytotoxic CD8(+) T cells. Finally, priming with the naked...

24 CFR 85.41 - Financial reporting.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Financial reporting. 85.41 Section... § 85.41 Financial reporting. (a) General. (1) Except as provided in paragraphs (a) (2) and (5) of this... financial reports to Federal agencies, or (ii) Requesting advances or reimbursements when letters of credit...

o-Vanillin functionalized mesoporous silica – coated magnetite nanoparticles for efficient removal of Pb(II) from water

Energy Technology Data Exchange (ETDEWEB)

Culita, Daniela C., E-mail: danaculita@yahoo.co.uk [“Ilie Murgulescu” Institute of Physical Chemistry, Splaiul Independentei 202, Bucharest (Romania); Simonescu, Claudia Maria; Patescu, Rodica-Elena [Politehnica University, Faculty of Applied Chemistry and Materials Science, Bucharest (Romania); Dragne, Mioara [S.C. KEMCRISTAL S.R.L., Muncii Str., No. 51, Fundulea, Călăraşi (Romania); Stanica, Nicolae [“Ilie Murgulescu” Institute of Physical Chemistry, Splaiul Independentei 202, Bucharest (Romania); Oprea, Ovidiu [Politehnica University, Faculty of Applied Chemistry and Materials Science, Bucharest (Romania)

2016-06-15

o-Vanillin functionalized mesoporous silica – coated magnetite (Fe{sub 3}O{sub 4}@MCM-41-N-oVan) was synthesized and fully characterized by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, N{sub 2} adsorption–desorption technique and magnetic measurements. The capacity of Fe{sub 3}O{sub 4}@MCM-41-N-oVan to adsorb Pb(II) from aqueous solutions was evaluated in comparison with raw mesoporous silica – coated magnetite (Fe{sub 3}O{sub 4}@MCM-41) and amino – modified mesoporous silica coated magnetite (Fe{sub 3}O{sub 4}@MCM-41-NH{sub 2}). The effect of adsorption process parameters such us pH, contact time, initial Pb(II) concentration was also investigated. The adsorption data were successfully fitted with the Langmuir model, exhibiting a maximum adsorption capacity of 155.71 mg/g at pH=4.4 and T=298 K. The results revealed that the adsorption rate was very high at the beginning of the adsorption process, 80–90% of the total amount of Pb(II) being removed within the first 60 min, depending on the initial concentration. The results of the present work suggest that Fe{sub 3}O{sub 4}@MCM-41-N-oVan is a suitable candidate for the separation of Pb(II) from contaminated water. - Graphical abstract: A novel magnetic adsorbent based on o-vanillin functionalized mesoporous silica – coated magnetite was synthesized and fully characterized and its adsorption capacity for Pb(II) ions in aqueous solutions was evaluated. The maximum adsorption capacity for Pb(II) ions was determined to be 155.71 mg g{sup −1}. The adsorption rate was very high at the beginning of the adsorption process, 90% of the total amount of Pb(II) being removed within the first 60 min. Display Omitted.

o-Vanillin functionalized mesoporous silica – coated magnetite nanoparticles for efficient removal of Pb(II) from water

International Nuclear Information System (INIS)

Culita, Daniela C.; Simonescu, Claudia Maria; Patescu, Rodica-Elena; Dragne, Mioara; Stanica, Nicolae; Oprea, Ovidiu

2016-01-01

o-Vanillin functionalized mesoporous silica – coated magnetite (Fe 3 O 4 @MCM-41-N-oVan) was synthesized and fully characterized by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, N 2 adsorption–desorption technique and magnetic measurements. The capacity of Fe 3 O 4 @MCM-41-N-oVan to adsorb Pb(II) from aqueous solutions was evaluated in comparison with raw mesoporous silica – coated magnetite (Fe 3 O 4 @MCM-41) and amino – modified mesoporous silica coated magnetite (Fe 3 O 4 @MCM-41-NH 2 ). The effect of adsorption process parameters such us pH, contact time, initial Pb(II) concentration was also investigated. The adsorption data were successfully fitted with the Langmuir model, exhibiting a maximum adsorption capacity of 155.71 mg/g at pH=4.4 and T=298 K. The results revealed that the adsorption rate was very high at the beginning of the adsorption process, 80–90% of the total amount of Pb(II) being removed within the first 60 min, depending on the initial concentration. The results of the present work suggest that Fe 3 O 4 @MCM-41-N-oVan is a suitable candidate for the separation of Pb(II) from contaminated water. - Graphical abstract: A novel magnetic adsorbent based on o-vanillin functionalized mesoporous silica – coated magnetite was synthesized and fully characterized and its adsorption capacity for Pb(II) ions in aqueous solutions was evaluated. The maximum adsorption capacity for Pb(II) ions was determined to be 155.71 mg g −1 . The adsorption rate was very high at the beginning of the adsorption process, 90% of the total amount of Pb(II) being removed within the first 60 min. Display Omitted

Gauge-invariant cosmological density perturbations

International Nuclear Information System (INIS)

Sasaki, Misao.

1986-06-01

Gauge-invariant formulation of cosmological density perturbation theory is reviewed with special emphasis on its geometrical aspects. Then the gauge-invariant measure of the magnitude of a given perturbation is presented. (author)

Identification of invariant measures of interacting systems

International Nuclear Information System (INIS)

Chen Jinwen

2004-01-01

In this paper we provide an approach for identifying certain mixture representations of some invariant measures of interacting stochastic systems. This is related to the problem of ergodicity of certain extremal invariant measures that are translation invariant. Corresponding to these, results concerning the existence of invariant measures and certain weak convergence of the systems are also provided

Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes

Directory of Open Access Journals (Sweden)

Feuer Gerold

2004-11-01

Full Text Available Abstract Background Human T-lymphotropic virus type-1 (HTLV-1 is a deltaretrovirus that causes adult T-cell leukemia/lymphoma and is implicated in a variety of lymphocyte-mediated disorders. HTLV-1 contains both regulatory and accessory genes in four pX open reading frames. pX ORF-II encodes two proteins, p13II and p30II, which are incompletely defined in the virus life cycle or HTLV-1 pathogenesis. Proviral clones of the virus with pX ORF-II mutations diminish the ability of the virus to maintain viral loads in vivo. Exogenous expression of p30II differentially modulates CREB and Tax-responsive element-mediated transcription through its interaction with CREB-binding protein/p300 and represses tax/rex RNA nuclear export. Results Herein, we further characterized the role of p30II in regulation of cellular gene expression, using stable p30II expression system employing lentiviral vectors to test cellular gene expression with Affymetrix U133A arrays, representing ~33,000 human genes. Reporter assays in Jurkat T cells and RT-PCR in Jurkat and primary CD4+ T-lymphocytes were used to confirm selected gene expression patterns. Our data reveals alterations of interrelated pathways of cell proliferation, T-cell signaling, apoptosis and cell cycle in p30II expressing Jurkat T cells. In all categories, p30II appeared to be an overall repressor of cellular gene expression, while selectively increasing the expression of certain key regulatory genes. Conclusions We are the first to demonstrate that p30II, while repressing the expression of many genes, selectively activates key gene pathways involved in T-cell signaling/activation. Collectively, our data suggests that this complex retrovirus, associated with lymphoproliferative diseases, relies upon accessory gene products to modify cellular environment to promote clonal expansion of the virus genome and thus maintain proviral loads in vivo.

Aspects of the quantization of theories with a gauge invariance

International Nuclear Information System (INIS)

Siopsis, G.

1987-01-01

First, we identify the Gribov problem that is encountered when the Faddeev-Popov procedure of fixing the gauge is employed to define a perturbation expansion. The author propose a modification of the procedure that takes this problem into account. We then apply this method to two-dimensional gauge theories where the exact answer is known. Second, we try to build chiral theories that are consistent in the presence of anomalies, without making use of additional degrees of freedom. We are able to solve the model exactly in two dimensions, arriving at a gauge-invariant theory. We discuss the four-dimensional case and also the application of this method to string theory. In the latter, we obtain a model that lives in arbitrary dimensions. However, we do not compute the spectrum of the model. Third, we investigate the possibility of compactifying the unwanted dimensions of superstrings on a group manifold. We give a complete list of conformally invariant models. We also discuss one-loop modular invariance. We consider both type-II and heterotic superstring theories. Fourth, we discuss quantization of string field theory. We start by presenting the lagrangian approach, to demonstrate the non-uniqueness of the measure in the path- integral. It is fixed by demanding unitarity, which manifests itself in the hamiltonian formulation, studied next

Revisiting measurement invariance in intelligence testing in aging research: Evidence for almost complete metric invariance across age groups.

Science.gov (United States)

Sprague, Briana N; Hyun, Jinshil; Molenaar, Peter C M

2017-01-01

Invariance of intelligence across age is often assumed but infrequently explicitly tested. Horn and McArdle (1992) tested measurement invariance of intelligence, providing adequate model fit but might not consider all relevant aspects such as sub-test differences. The goal of the current paper is to explore age-related invariance of the WAIS-R using an alternative model that allows direct tests of age on WAIS-R subtests. Cross-sectional data on 940 participants aged 16-75 from the WAIS-R normative values were used. Subtests examined were information, comprehension, similarities, vocabulary, picture completion, block design, picture arrangement, and object assembly. The two intelligence factors considered were fluid and crystallized intelligence. Self-reported ages were divided into young (16-22, n = 300), adult (29-39, n = 275), middle (40-60, n = 205), and older (61-75, n = 160) adult groups. Results suggested partial metric invariance holds. Although most of the subtests reflected fluid and crystalized intelligence similarly across different ages, invariance did not hold for block design on fluid intelligence and picture arrangement on crystallized intelligence for older adults. Additionally, there was evidence of a correlated residual between information and vocabulary for the young adults only. This partial metric invariance model yielded acceptable model fit compared to previously-proposed invariance models of Horn and McArdle (1992). Almost complete metric invariance holds for a two-factor model of intelligence. Most of the subtests were invariant across age groups, suggesting little evidence for age-related bias in the WAIS-R. However, we did find unique relationships between two subtests and intelligence. Future studies should examine age-related differences in subtests when testing measurement invariance in intelligence.

Construction of exact complex dynamical invariant of a two ...

Indian Academy of Sciences (India)

system possesses a complex invariant, namely u = ln(p + imωx) − iωt [6]. ... gaining importance for explaining several phenomena [10] such as the resonance .... then H1 and H2 satisfy the Cauchy–Riemann conditions [18] and after employing.

Constructing Invariant Fairness Measures for Surfaces

DEFF Research Database (Denmark)

Gravesen, Jens; Ungstrup, Michael

1998-01-01

of the size of this vector field is used as the fairness measure on the family.Six basic 3rd order invariants satisfying two quadratic equations are defined. They form a complete set in the sense that any invariant 3rd order function can be written as a function of the six basic invariants together...

Flash photolysis ESR study of photosystem II signal II/sub vf/, the physiological donor to P-680/sup +/

Energy Technology Data Exchange (ETDEWEB)

Warden, J T [Rensselaer Polytechnic Inst., Troy, NY; Blankenship, R E; Sauer, K

1976-01-01

In flash-illuminated, oxygen-evolving spinach chloroplasts and green algae, a free radical transient has been observed with spectral parameters similar to those of Signal II (g approx. = 2.0045, ..delta..H/sub pp/ approx. = 19 G). However, in contrast with ESR Signal II, the transient radical does not readily saturate even at microwave power levels of 200 mW. This species is formed most efficiently with ''red'' illumination (lambda < 680 nm) and occurs stoichiometrically in a 1:1 ratio with P-700/sup +/. The Photosystem II transient is formed in less than 100 ..mu..s and decays via first-order kinetics with a halftime of 400-900 ..mu..s. Additionally, the t/sub /sup 1///sub 2// for radical decay is temperature independent between 20 and 4/sup 0/C; however, below 4/sup 0/C the transient signal exhibits Arrhenius behavior with an activation energy of approx. 10 kcal . mol/sup -1/. Inhibition of electron transport through Photosystem II by o-phenanthroline, 3-(3,4-dichlorophenyl)-1,1-dimethylurea or reduced 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone suppresses the formation of the light-induced transient. At low concentrations (0.2 mM), 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone partially inhibits the free radical formation, however, the decay kinetics are unaltered. High concentrations of 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone (1-5 mM) restore both the transient signal and electron flow through Photosystem II. These findings suggest that this ''quinoidal'' type ESR transient functions as the physiological donor to the oxidized reaction center chlorophyll, P-680/sup +/.

On logarithmic extensions of local scale-invariance

International Nuclear Information System (INIS)

Henkel, Malte

2013-01-01

Ageing phenomena far from equilibrium naturally present dynamical scaling and in many situations this may be generalised to local scale-invariance. Generically, the absence of time-translation-invariance implies that each scaling operator is characterised by two independent scaling dimensions. Building on analogies with logarithmic conformal invariance and logarithmic Schrödinger-invariance, this work proposes a logarithmic extension of local scale-invariance, without time-translation-invariance. Carrying this out requires in general to replace both scaling dimensions of each scaling operator by Jordan cells. Co-variant two-point functions are derived for the most simple case of a two-dimensional logarithmic extension. Their form is compared to simulational data for autoresponse functions in several universality classes of non-equilibrium ageing phenomena

Copper(II) complexes with 4-(1H-1, 2, 4-trizol-1-ylmethyl) benzoic acid: Syntheses, crystal structures and antifungal activities

Energy Technology Data Exchange (ETDEWEB)

Xiong, Pingping [Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi' an 710069 (China); Li, Jie [Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), Shaanxi Provincial Key Laboratory of Biotechnology, Xi' an 710069 (China); Bu, Huaiyu, E-mail: 7213792@qq.com [Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), Shaanxi Provincial Key Laboratory of Biotechnology, Xi' an 710069 (China); Wei, Qing [Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi' an 710069 (China); Zhang, Ruolin [Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), Shaanxi Provincial Key Laboratory of Biotechnology, Xi' an 710069 (China); Chen, Sanping, E-mail: sanpingchen@126.com [Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry and Materials Science, Northwest University, Xi' an 710069 (China)

2014-07-01

Reaction of Cu(II) with an asymmetric semi-rigid organic ligand 4-(1H-1, 2, 4-trizol-1-ylmethyl) benzoic acid (HL), yielded five compounds, [Cu{sub 0.5}L]{sub n} (1), [Cu(HL){sub 2}Cl{sub 2}]{sub n} (2), [Cu(HL){sub 2}Cl{sub 2}(H{sub 2}O)] (3), [Cu(L){sub 2}(H{sub 2}O)]{sub n} (4) and [Cu(L)(phen)(HCO{sub 2})]{sub n} (5), which have been fully characterized by infrared spectroscopy, elemental analysis, and single-crystal X-ray diffraction. As for compounds 1, 2 and 5, Cu(II) is bridged through HL, Cl{sup -}, and formic acid, respectively, featuring 1D chain-structure. In compound 3, Cu(II) with hexahedral coordination sphere is assembled through hydrogen-bonding into 3D supramolecular framework. In compound 4, 1D chain units –Cu–O–Cu–O– are ligand-bridged into a 3D network. All compounds were tested on fungi (Fusarium graminearum, Altemaria solani, Macrophoma kawatsukai, Alternaria alternata and Colletotrichum gloeosporioides). Compound 1 exhibits a better antifungal effect compared to other compounds. An effect of structure on the antifungal activity has also been correlated. - Graphical abstract: Copper(II) compounds with 4-(1H-1, 2, 4-trizol-1-ylmethyl) benzoic acid, were prepared, structurally characterized and investigated for antifungal activity. - Highlights: • The title compounds formed by thermodynamics and thermokinetics. • The five compounds show higher inhibition percentage than reactants. • The structure effect on the antifungal activity.

Characteristics of lead(II) adsorption onto "Natural Red Earth" in simulated environmental conditions

Science.gov (United States)

Mahatantila, K.; Vithanage, M. S.; Seike, Y.; Okumura, M.

2011-12-01

Lead is considered as a non-biodegradable and potentially toxic heavy metal and it is found as a common environmental pollutant. Adsorption characteristics of Pb(II) onto natural iron and aluminum coated sand, which is called Natural Red Earth (NRE), have been studied to ascertain the effect of pH, ionic strength, initial sorbate concentrations, temperature and time. Lead(II) adsorption achieved its maximum adsorption of nearly 100% at neutral to slightly acidic conditions. The optimum pH was nearly 5.5 and 6.5 for 2.41 and 24.1 μmol/L initial Pb(II) concentrations, respectively. Lead(II) adsorption was independent of 100 fold variation of ionic strength (0.001 - 0.1), indirectly evidencing dominance of an inner-sphere surface complexation mechanism for 10 fold variation of initial Pb(II) concentrations (2.41 and 24.1 μmol/L). Adsorption edges were quantified with a 2pK generalized diffuse double layer model considering two site types, >FeOH and >AlOH, for Pb(II) binding. The modeling results better fit with the mixture of monodentate and bidentated binding of Pb(II) onto >FeOH site and bidentate binding of Pb(II) onto >AlOH site. The intrinsic constants obtained were log KFeOPb=13.93, log K(FeO)2Pb=11.88 and log K(AlO)2Pb=13.21. Time required to reach the equilibrium was also increase from 15 min to 1hr with increasing Pb(II) concentrations from 2.41 to 24.1 μmol/L. Kinetic data fitted better to pseudo second order kinetic model. Lead(II) adsorption onto NRE was better explained by Two-site Langmuir isotherm with sorption maximum of 1.39x10-2 and 2.30x10-3 mol/kg for two sites with different affinities. Negative Gibbs free energy values indicated spontaneity of Pb(II) adsorption onto NRE, and entropy and enthalpy of adsorption were 124.04 J/K mol and 17.71 KJ/mol, respectively. These results suggested that the NRE could be effectively used as a low cost candidate for removal of Pb(II) from environmental water, since use of low cost materials to treat

Nonlocal, yet translation invariant, constraints for rotationally invariant slave bosons

Science.gov (United States)

Ayral, Thomas; Kotliar, Gabriel

The rotationally-invariant slave boson (RISB) method is a lightweight framework allowing to study the low-energy properties of complex multiorbital problems currently out of the reach of more comprehensive, yet more computationally demanding methods such as dynamical mean field theory. In the original formulation of this formalism, the slave-boson constraints can be made nonlocal by enlarging the unit cell and viewing the quantum states enclosed in this new unit cell as molecular levels. In this work, we extend RISB to constraints which are nonlocal while preserving translation invariance. We apply this extension to the Hubbard model.

An extension of Brosowski-Meinardus theorem on invariant approximation

International Nuclear Information System (INIS)

Liaqat Ali Khan; Abdul Rahim Khan.

1991-07-01

We obtain a generalization of a fixed point theorem of Dotson for non-expansive mappings on star-shaped sets and then use it to prove a unified Brosowski-Meinardus theorem on invariant approximation in the setting of p-normed linear spaces. (author). 13 refs

Unified models of interactions with gauge-invariant variables

International Nuclear Information System (INIS)

Zet, Gheorghe

2000-01-01

A model of gauge theory is formulated in terms of gauge-invariant variables over a 4-dimensional space-time. Namely, we define a metric tensor g μν ( μ , ν = 0,1,2,3) starting with the components F μν a and F μν a tilde of the tensor associated to the Yang-Mills fields and its dual: g μν = 1/(3Δ 1/3 ) (ε abc F μα a F αβ b tilde F βν c ). Here Δ is a scale factor which can be chosen of a convenient form so that the theory may be self-dual or not. The components g μν are interpreted as new gauge-invariant variables. The model is applied to the case when the gauge group is SU(2). For the space-time we choose two different manifolds: (i) the space-time is R x S 3 , where R is the real line and S 3 is the three-dimensional sphere; (ii) the space-time is endowed with axial symmetry. We calculate the components g μν of the new metric for the two cases in terms of SU(2) gauge potentials. Imposing the supplementary condition that the new metric coincides with the initial metric of the space-time, we obtain the field equations (of the first order in derivatives) for the gauge fields. In addition, we determine the scale factor Δ which is introduced in the definition of g μν to ensure the property of self-duality for our SU(2) gauge theory, namely, 1/(2√g)(ε αβστ g μα g νβ F στ a = F μν a , g = det (g μν ). In the case (i) we show that the space-time R x S 3 is not compatible with a self-dual SU(2) gauge theory, but in the case (ii) the condition of self-duality is satisfied. The model developed in our work can be considered as a possible way to unification of general relativity and Yang-Mills theories. This means that the gauge theory can be formulated in the close analogy with the general relativity, i.e. the Yang-Mills equations are equivalent to Einstein equations with the right-hand side of a simple form. (authors)

Torsional Topological Invariants (and their relevance for real life)

CERN Document Server

Chandia, O; Chandia, Osvaldo; Zanelli, Jorge

1997-01-01

The existence of topological invariants analogous to Chern/Pontryagin classes for a standard $SO(D)$ or SU(N) connection, but constructed out of the torsion tensor, is discussed. These invariants exhibit many of the features of the Chern/Pontryagin invariants: they can be expressed as integrals over the manifold of local densities and take integer values on compact spaces without boundary; their spectrum is determined by the homotopy groups determined by the connection bundle but depend also on the bundle of local orthonormal frames on the tangent space of the manifold. It is shown that in spacetimes with nonvanishing torsion there can occur topologically stable configurations associated with the frame bundle which are independent of the curvature. Explicit examples of topologically stable configurations carrying nonvanishing instanton number in four and eight dimensions are given, and they can be conjectured to exist in dimension $4k$. It is also shown that the chiral anomaly in a spacetime with torsion rece...

ER, p53 and MIB-1 are significantly associated with malignant phyllodes tumor.

Science.gov (United States)

Munawer, Nurhayati H; Md Zin, Reena; Md Ali, Siti-Aishah; Muhammad, Rohaizak; Ali, Jasmi; Das, Srijit

2012-01-01

Fibroadenomas (FA) are common while phyllodes tumors (PT) are rare and both tumors are composed of epithelial and stromal components. We evaluated the expression status of ER, Bc12, p53, and MIB-1 protein in these tumors. One hundred and ninety-three tumors comprising of 117 FAs and 76 PTs were examined using immunohistochemistry on tissue microarray. The mean age of patients with FA was 28.5 years while the mean ages of patients with benign, borderline and malignant PTs were 41.7, 48.6 and 42.1 years, respectively. Also all types of PTs were large (>Scm). ER showed a strong nuclear staining in the epithelial component of all tumors while ER/3 immunoreactivity was detected in both the epithelial and stromal components ofF A and PT. ER/β (pcomponent were associated with tumor size. p53 expression was significantly associated with both the epithelial and stromal components of malignant PTs (pcomponent (p=0.000). In addition, MIB-1 was also found to be associated with ER and ER/3 in the stromal component (p=0.000). The expression of p53 with tumor size and histological grade in PT may increase the risk for malignancy.

One-hole states in nuclei of 41K, 41Ca and 41Sc

International Nuclear Information System (INIS)

Kim, Moon Won

1985-01-01

The one-hole states in nuclei of 41 K, 41 Ca and 41 Sc have been calculated with a model space based on the (1f 7/2 ,2P 3/2 ) 2 (1d 3/2 , 2S 1/2 ) -1 configuration using the nuclear shell model. The two body effective interaction is assumed to be a surface-delta potential. 40 Ca is also assumed to be an inert core. Energy spectra and spectroscopic factors are obtained and compared with the experimental data. The calculate results in fair agreement with the observed values. (Author)

Analytic invariants of boundary links

OpenAIRE

Garoufalidis, Stavros; Levine, Jerome

2001-01-01

Using basic topology and linear algebra, we define a plethora of invariants of boundary links whose values are power series with noncommuting variables. These turn out to be useful and elementary reformulations of an invariant originally defined by M. Farber.

Status of time reversal invariance

International Nuclear Information System (INIS)

Henley, E.M.

1989-01-01

Time Reversal Invariance is introduced, and theories for its violation are reviewed. The present experimental and theoretical status of Time Reversal Invariance and tests thereof will be presented. Possible future tests will be discussed. 30 refs., 2 figs., 1 tab

Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy.

Science.gov (United States)

Heczey, Andras; Liu, Daofeng; Tian, Gengwen; Courtney, Amy N; Wei, Jie; Marinova, Ekaterina; Gao, Xiuhua; Guo, Linjie; Yvon, Eric; Hicks, John; Liu, Hao; Dotti, Gianpietro; Metelitsa, Leonid S

2014-10-30

Advances in the design of chimeric antigen receptors (CARs) have improved the antitumor efficacy of redirected T cells. However, functional heterogeneity of CAR T cells limits their therapeutic potential and is associated with toxicity. We proposed that CAR expression in Vα24-invariant natural killer T (NKT) cells can build on the natural antitumor properties of these cells while their restriction by monomorphic CD1d limits toxicity. Primary human NKT cells were engineered to express a CAR against the GD2 ganglioside (CAR.GD2), which is highly expressed by neuroblastoma (NB). We compared CAR.GD2 constructs that encoded the CD3ζ chain alone, with CD28, 4-1BB, or CD28 and 4-1BB costimulatory endodomains. CAR.GD2 expression rendered NKT cells highly cytotoxic against NB cells without affecting their CD1d-dependent reactivity. We observed a striking T helper 1-like polarization of NKT cells by 4-1BB-containing CARs. Importantly, expression of both CD28 and 4-1BB endodomains in the CAR.GD2 enhanced in vivo persistence of NKT cells. These CAR.GD2 NKT cells effectively localized to the tumor site had potent antitumor activity, and repeat injections significantly improved the long-term survival of mice with metastatic NB. Unlike T cells, CAR.GD2 NKT cells did not induce graft-versus-host disease. These results establish the potential of NKT cells to serve as a safe and effective platform for CAR-directed cancer immunotherapy. © 2014 by The American Society of Hematology.

Summational invariants

International Nuclear Information System (INIS)

Mackrodt, C.; Reeh, H.

1997-01-01

General summational invariants, i.e., conservation laws acting additively on asymptotic particle states, are investigated within a classical framework for point particles with nontrivial scattering. copyright 1997 American Institute of Physics

Dynamical topological invariant after a quantum quench

Science.gov (United States)

Yang, Chao; Li, Linhu; Chen, Shu

2018-02-01

We show how to define a dynamical topological invariant for one-dimensional two-band topological systems after a quantum quench. By analyzing general two-band models of topological insulators, we demonstrate that the reduced momentum-time manifold can be viewed as a series of submanifolds S2, and thus we are able to define a dynamical topological invariant on each of the spheres. We also unveil the intrinsic relation between the dynamical topological invariant and the difference in the topological invariant of the initial and final static Hamiltonian. By considering some concrete examples, we illustrate the calculation of the dynamical topological invariant and its geometrical meaning explicitly.

Phenomenology of local scale invariance: from conformal invariance to dynamical scaling

International Nuclear Information System (INIS)

Henkel, Malte

2002-01-01

Statistical systems displaying a strongly anisotropic or dynamical scaling behaviour are characterized by an anisotropy exponent θ or a dynamical exponent z. For a given value of θ (or z), we construct local scale transformations, which can be viewed as scale transformations with a space-time-dependent dilatation factor. Two distinct types of local scale transformations are found. The first type may describe strongly anisotropic scaling of static systems with a given value of θ, whereas the second type may describe dynamical scaling with a dynamical exponent z. Local scale transformations act as a dynamical symmetry group of certain non-local free-field theories. Known special cases of local scale invariance are conformal invariance for θ=1 and Schroedinger invariance for θ=2. The hypothesis of local scale invariance implies that two-point functions of quasi primary operators satisfy certain linear fractional differential equations, which are constructed from commuting fractional derivatives. The explicit solution of these yields exact expressions for two-point correlators at equilibrium and for two-point response functions out of equilibrium. A particularly simple and general form is found for the two-time auto response function. These predictions are explicitly confirmed at the uniaxial Lifshitz points in the ANNNI and ANNNS models and in the aging behaviour of simple ferromagnets such as the kinetic Glauber-Ising model and the kinetic spherical model with a non-conserved order parameter undergoing either phase-ordering kinetics or non-equilibrium critical dynamics

Quantifying Translation-Invariance in Convolutional Neural Networks

OpenAIRE

Kauderer-Abrams, Eric

2017-01-01

A fundamental problem in object recognition is the development of image representations that are invariant to common transformations such as translation, rotation, and small deformations. There are multiple hypotheses regarding the source of translation invariance in CNNs. One idea is that translation invariance is due to the increasing receptive field size of neurons in successive convolution layers. Another possibility is that invariance is due to the pooling operation. We develop a simple ...

Invariant measures in brain dynamics

International Nuclear Information System (INIS)

Boyarsky, Abraham; Gora, Pawel

2006-01-01

This note concerns brain activity at the level of neural ensembles and uses ideas from ergodic dynamical systems to model and characterize chaotic patterns among these ensembles during conscious mental activity. Central to our model is the definition of a space of neural ensembles and the assumption of discrete time ensemble dynamics. We argue that continuous invariant measures draw the attention of deeper brain processes, engendering emergent properties such as consciousness. Invariant measures supported on a finite set of ensembles reflect periodic behavior, whereas the existence of continuous invariant measures reflect the dynamics of nonrepeating ensemble patterns that elicit the interest of deeper mental processes. We shall consider two different ways to achieve continuous invariant measures on the space of neural ensembles: (1) via quantum jitters, and (2) via sensory input accompanied by inner thought processes which engender a 'folding' property on the space of ensembles

Quantum invariants of knots and 3-manifolds. 2. rev. ed.

International Nuclear Information System (INIS)

Turaev, Vladimir G.

2010-01-01

Due to the strong appeal and wide use of this monograph, it is now available in its second revised edition. The monograph gives a systematic treatment of 3-dimensional topological quantum field theories (TQFTs) based on the work of the author with N. Reshetikhin and O. Viro. This subject was inspired by the discovery of the Jones polynomial of knots and the Witten-Chern-Simons field theory. On the algebraic side, the study of 3-dimensional TQFTs has been influenced by the theory of braided categories and the theory of quantum groups. The book is divided into three parts. Part I presents a construction of 3-dimensional TQFTs and 2-dimensional modular functors from so-called modular categories. This gives a vast class of knot invariants and 3-manifold invariants as well as a class of linear representations of the mapping class groups of surfaces. In Part II the technique of 6j-symbols is used to define state sum invariants of 3-manifolds. Their relation to the TQFTs constructed in Part I is established via the theory of shadows. Part III provides constructions of modular categories, based on quantum groups and skein modules of tangles in the 3-space. This fundamental contribution to topological quantum field theory is accessible to graduate students in mathematics and physics with knowledge of basic algebra and topology. It is an indispensable source for everyone who wishes to enter the forefront of this fascinating area at the borderline of mathematics and physics. From the contents: - Invariants of graphs in Euclidean 3-space and of closed 3-manifolds - Foundations of topological quantum field theory - Three-dimensional topological quantum field theory - Two-dimensional modular functors - 6j-symbols - Simplicial state sums on 3-manifolds - Shadows of manifolds and state sums on shadows - Constructions of modular categories. (orig.)

The usage of color invariance in SURF

Science.gov (United States)

Meng, Gang; Jiang, Zhiguo; Zhao, Danpei

2009-10-01

SURF (Scale Invariant Feature Transform) is a robust local invariant feature descriptor. However, SURF is mainly designed for gray images. In order to make use of the information provided by color (mainly RGB channels), this paper presents a novel colored local invariant feature descriptor, CISURF (Color Invariance based SURF). The proposed approach builds the descriptors in a color invariant space, which stems from Kubelka-Munk model and provides more valuable information than the gray space. Compared with the conventional SURF and SIFT descriptors, the experimental results show that descriptors created by CISURF is more robust to the circumstance changes such as the illumination direction, illumination intensity, and the viewpoints, and are more suitable for the deep space background objects.

Cross section and panti p invariant mass distribution of the reaction γp → panti pp at 4.74-6.55 GeV, an experimental investigation

International Nuclear Information System (INIS)

Bodenkamp, J.

1981-08-01

This paper gives a report of a photoproduction experiment of proton-antiproton pairs on hydrogen in the elastic reaction γp → panti pp which was performed at the Deutsches Elektronensynchrotron in Hamburg. The results of our measurements do not show substantial energy dependence in the energy range in our experiment. We obtain an integrated cross section of 79.6 +- 6 nbarn for the investigated reaction. Data accumulations could be observed in the invariant mass distribution of the proton antiproton pairs at 1940 MeV/c 2 and 2020 MeV/c 2 . The signal at 2020 MeV/c 2 has a statistical significance of 3.5 standard deviations and is in agreement with a resonance of the panti p-system reported in earlier experiments, a Breit-Wigner fit to the data yielded for mass msub(o) and width GAMMAsub(o) of this signal m 0 = 2.023 +- .005 GeV/c 2 GAMMA 0 = 27 +- 12 MeV/c 2 . (orig./HSI) [de

Anisotropic Weyl invariance

Energy Technology Data Exchange (ETDEWEB)

Perez-Nadal, Guillem [Universidad de Buenos Aires, Buenos Aires (Argentina)

2017-07-15

We consider a non-relativistic free scalar field theory with a type of anisotropic scale invariance in which the number of coordinates ''scaling like time'' is generically greater than one. We propose the Cartesian product of two curved spaces, the metric of each space being parameterized by the other space, as a notion of curved background to which the theory can be extended. We study this type of geometries, and find a family of extensions of the theory to curved backgrounds in which the anisotropic scale invariance is promoted to a local, Weyl-type symmetry. (orig.)

The invariant theory of matrices

CERN Document Server

Concini, Corrado De

2017-01-01

This book gives a unified, complete, and self-contained exposition of the main algebraic theorems of invariant theory for matrices in a characteristic free approach. More precisely, it contains the description of polynomial functions in several variables on the set of m\\times m matrices with coefficients in an infinite field or even the ring of integers, invariant under simultaneous conjugation. Following Hermann Weyl's classical approach, the ring of invariants is described by formulating and proving the first fundamental theorem that describes a set of generators in the ring of invariants, and the second fundamental theorem that describes relations between these generators. The authors study both the case of matrices over a field of characteristic 0 and the case of matrices over a field of positive characteristic. While the case of characteristic 0 can be treated following a classical approach, the case of positive characteristic (developed by Donkin and Zubkov) is much harder. A presentation of this case...

EMPLOYEE COMMITMENT ACROSS COUNTRIES AND TIMES - MEASUREMENT INVARIANCE

Directory of Open Access Journals (Sweden)

Dana Mesner Andolšek

2015-01-01

Full Text Available Employee organisational commitment has been long and extensively studied until now (Meyer & Allen, 1997; Jaussi, 2007.An emphasis of current analysis was to verify its measurement characteristics, for the purpose of comparisons of levels of commitment across time and countries. A limited set of countries was chosen among those available in a sample from the data on Work Orientations II, ISSP 1997, purpose fully selected to reflect cultural and structural differences that was expected to affect change in levels of organisational commitment. With the use of structural equations models we first confirmed that a model for configural invariance for two factors measuring conceptually distinct components of Affective commitment (AC and Continuance commitment (CC respectively has better support than of one factor model. Metric and error term invariance was subsequently confirmed. Scalar equivalence, needed for valid comparison of mean levels of both components of commitment, was confirmed as well, with the exception of two country specific Tau coefficient. Finally, a model thus established was applied additionally on data from2005 ISSP. Acceptable fit was achieved for a common model containing both points in time and all countries, which allowed making more firm conclusions about the changes in AC and CC in different countries.

Integral reinforcement learning for continuous-time input-affine nonlinear systems with simultaneous invariant explorations.

Science.gov (United States)

Lee, Jae Young; Park, Jin Bae; Choi, Yoon Ho

2015-05-01

This paper focuses on a class of reinforcement learning (RL) algorithms, named integral RL (I-RL), that solve continuous-time (CT) nonlinear optimal control problems with input-affine system dynamics. First, we extend the concepts of exploration, integral temporal difference, and invariant admissibility to the target CT nonlinear system that is governed by a control policy plus a probing signal called an exploration. Then, we show input-to-state stability (ISS) and invariant admissibility of the closed-loop systems with the policies generated by integral policy iteration (I-PI) or invariantly admissible PI (IA-PI) method. Based on these, three online I-RL algorithms named explorized I-PI and integral Q -learning I, II are proposed, all of which generate the same convergent sequences as I-PI and IA-PI under the required excitation condition on the exploration. All the proposed methods are partially or completely model free, and can simultaneously explore the state space in a stable manner during the online learning processes. ISS, invariant admissibility, and convergence properties of the proposed methods are also investigated, and related with these, we show the design principles of the exploration for safe learning. Neural-network-based implementation methods for the proposed schemes are also presented in this paper. Finally, several numerical simulations are carried out to verify the effectiveness of the proposed methods.

Measurement of the Moments of the Hadronic Invariant Mass Distribution in Semileptonic B Decays

International Nuclear Information System (INIS)

Acosta, D.

2005-01-01

Using 180 pb -1 of data collected with the CDF II detector at the Tevatron, we measure the first two moments of the hadronic invariant mass-squared distribution in charmed semileptonic B decays. From these we determine the non-perturbative Heavy Quark Effective Theory parameters Λ and λ 1 used to relate the B meson semileptonic branching ratio to the CKM matrix element |V cb |

Scale invariant Volkov–Akulov supergravity

Energy Technology Data Exchange (ETDEWEB)

Ferrara, S., E-mail: sergio.ferrara@cern.ch [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); INFN – Laboratori Nazionali di Frascati, Via Enrico Fermi 40, 00044 Frascati (Italy); Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1547 (United States); Porrati, M., E-mail: mp9@nyu.edu [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); CCPP, Department of Physics, NYU, 4 Washington Pl., New York, NY 10003 (United States); Sagnotti, A., E-mail: sagnotti@sns.it [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); Scuola Normale Superiore and INFN, Piazza dei Cavalieri 7, 56126 Pisa (Italy)

2015-10-07

A scale invariant goldstino theory coupled to supergravity is obtained as a standard supergravity dual of a rigidly scale-invariant higher-curvature supergravity with a nilpotent chiral scalar curvature. The bosonic part of this theory describes a massless scalaron and a massive axion in a de Sitter Universe.

Synthesis of cobalt-containing mesoporous catalysts using the ultrasonic-assisted “pH-adjusting” method: Importance of cobalt species in styrene oxidation

Energy Technology Data Exchange (ETDEWEB)

Li, Baitao, E-mail: btli@scut.edu.cn; Zhu, Yanrun; Jin, Xiaojing

2015-01-15

Cobalt-containing SBA-15 and MCM-41 (Co-SBA-15 and Co-MCM-41) mesoporous catalysts were prepared via ultrasonic-assisted “pH-adjusting” technique in this study. Their physiochemical structures were comprehensively characterized and correlated with catalytic activity in oxidation of styrene. The nature of cobalt species depended on the type of mesoporous silica as well as pH values. The different catalytic performance between Co-SBA-15 and Co-MCM-41 catalysts originated from cobalt species. Cobalt species were homogenously incorporated into the siliceous framework of Co-SBA-15 in single-site Co(II) state, while Co{sub 3}O{sub 4} particles were loaded on Co-MCM-41 catalysts. The styrene oxidation tests showed that the single-site Co(II) state was more beneficial to the catalytic oxidation of styrene. The higher styrene conversion and benzaldehyde selectivity over Co-SBA-15 catalysts were mainly attributed to single-site Co(II) state incorporated into the framework of SBA-15. The highest conversion of styrene (34.7%) with benzaldehyde selectivity of 88.2% was obtained over Co-SBA-15 catalyst prepared at pH of 7.5, at the mole ratio of 1:1 (styrene to H{sub 2}O{sub 2}) at 70 °C. - Graphical abstract: Cobalt-containing mesoporous silica catalysts were developed via ultrasonic-assisted “pH-adjusting” technique. Compared with Co{sub 3}O{sub 4} in Co-MCM-41, the single-site Co(II) state in Co-SBA-15 was more efficient for the styrene oxidation. - Highlights: • Fast and cost-effective ultrasonic technique for preparing mesoporous materials. • Incorporation of Co via ultrasonic irradiation and “pH-adjusting”. • Physicochemical comparison between Co-SBA-15 and Co-MCM-41. • Correlation of styrene oxidation activity and catalyst structural property.

On the invariance principle

Energy Technology Data Exchange (ETDEWEB)

Moller-Nielsen, Thomas [University of Oxford (United Kingdom)

2014-07-01

Physicists and philosophers have long claimed that the symmetries of our physical theories - roughly speaking, those transformations which map solutions of the theory into solutions - can provide us with genuine insight into what the world is really like. According to this 'Invariance Principle', only those quantities which are invariant under a theory's symmetries should be taken to be physically real, while those quantities which vary under its symmetries should not. Physicists and philosophers, however, are generally divided (or, indeed, silent) when it comes to explaining how such a principle is to be justified. In this paper, I spell out some of the problems inherent in other theorists' attempts to justify this principle, and sketch my own proposed general schema for explaining how - and when - the Invariance Principle can indeed be used as a legitimate tool of metaphysical inference.

A functional LMO invariant for Lagrangian cobordisms

DEFF Research Database (Denmark)

Cheptea, Dorin; Habiro, Kazuo; Massuyeau, Gwénaël

2008-01-01

Lagrangian cobordisms are three-dimensional compact oriented cobordisms between once-punctured surfaces, subject to some homological conditions. We extend the Le–Murakami–Ohtsuki invariant of homology three-spheres to a functor from the category of Lagrangian cobordisms to a certain category...... of Jacobi diagrams. We prove some properties of this functorial LMO invariant, including its universality among rational finite-type invariants of Lagrangian cobordisms. Finally, we apply the LMO functor to the study of homology cylinders from the point of view of their finite-type invariants....

Issues associated with Galilean invariance on a moving solid boundary in the lattice Boltzmann method

Science.gov (United States)

Peng, Cheng; Geneva, Nicholas; Guo, Zhaoli; Wang, Lian-Ping

2017-01-01

In lattice Boltzmann simulations involving moving solid boundaries, the momentum exchange between the solid and fluid phases was recently found to be not fully consistent with the principle of local Galilean invariance (GI) when the bounce-back schemes (BBS) and the momentum exchange method (MEM) are used. In the past, this inconsistency was resolved by introducing modified MEM schemes so that the overall moving-boundary algorithm could be more consistent with GI. However, in this paper we argue that the true origin of this violation of Galilean invariance (VGI) in the presence of a moving solid-fluid interface is due to the BBS itself, as the VGI error not only exists in the hydrodynamic force acting on the solid phase, but also in the boundary force exerted on the fluid phase, according to Newton's Third Law. The latter, however, has so far gone unnoticed in previously proposed modified MEM schemes. Based on this argument, we conclude that the previous modifications to the momentum exchange method are incomplete solutions to the VGI error in the lattice Boltzmann method (LBM). An implicit remedy to the VGI error in the LBM and its limitation is then revealed. To address the VGI error for a case when this implicit remedy does not exist, a bounce-back scheme based on coordinate transformation is proposed. Numerical tests in both laminar and turbulent flows show that the proposed scheme can effectively eliminate the errors associated with the usual bounce-back implementations on a no-slip solid boundary, and it can maintain an accurate momentum exchange calculation with minimal computational overhead.

Continuous Integrated Invariant Inference, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — The proposed project will develop a new technique for invariant inference and embed this and other current invariant inference and checking techniques in an...

Interleukin-1 Receptor Antagonist and Interleukin-4 Genes Variable Number Tandem Repeats Are Associated with Adiposity in Malaysian Subjects

Directory of Open Access Journals (Sweden)

Yung-Yean Kok

2017-01-01

Full Text Available Interleukin-1 receptor antagonist (IL1RA intron 2 86 bp repeat and interleukin-4 (IL4 intron 3 70 bp repeat are variable number tandem repeats (VNTRs that have been associated with various diseases, but their role in obesity is elusive. The objective of this study was to investigate the association of IL1RA and IL4 VNTRs with obesity and adiposity in 315 Malaysian subjects (128 M/187 F; 23 Malays/251 ethnic Chinese/41 ethnic Indians. The allelic distributions of IL1RA and IL4 were significantly different among ethnicities, and the alleles were associated with total body fat (TBF classes. Individuals with IL1RA I/II genotype or allele II had greater risk of having higher overall adiposity, relative to those having the I/I genotype or I allele, respectively, even after controlling for ethnicity [Odds Ratio (OR of I/II genotype = 12.21 (CI = 2.54, 58.79; p=0.002; II allele = 5.78 (CI = 1.73, 19.29; p=0.004]. However, IL4 VNTR B2 allele was only significantly associated with overall adiposity status before adjusting for ethnicity [OR = 1.53 (CI = 1.04, 2.23; p=0.03]. Individuals with IL1RA II allele had significantly higher TBF than those with I allele (31.79±2.52 versus 23.51±0.40; p=0.005. Taken together, IL1RA intron 2 VNTR seems to be a genetic marker for overall adiposity status in Malaysian subjects.

Test of charge conjugation invariance

International Nuclear Information System (INIS)

Nefkens, B.M.K.; Prakhov, S.; Gaardestig, A.; Clajus, M.; Marusic, A.; McDonald, S.; Phaisangittisakul, N.; Price, J.W.; Starostin, A.; Tippens, W.B.; Allgower, C.E.; Spinka, H.; Bekrenev, V.; Koulbardis, A.; Kozlenko, N.; Kruglov, S.; Lopatin, I.; Briscoe, W.J.; Shafi, A.; Comfort, J.R.

2005-01-01

We report on the first determination of upper limits on the branching ratio (BR) of η decay to π 0 π 0 γ and to π 0 π 0 π 0 γ. Both decay modes are strictly forbidden by charge conjugation (C) invariance. Using the Crystal Ball multiphoton detector, we obtained BR(η→π 0 π 0 γ) -4 at the 90% confidence level, in support of C invariance of isoscalar electromagnetic interactions of the light quarks. We have also measured BR(η→π 0 π 0 π 0 γ) -5 at the 90% confidence level, in support of C invariance of isovector electromagnetic interactions

Scale invariant Volkov–Akulov supergravity

Directory of Open Access Journals (Sweden)

S. Ferrara

2015-10-01

Full Text Available A scale invariant goldstino theory coupled to supergravity is obtained as a standard supergravity dual of a rigidly scale-invariant higher-curvature supergravity with a nilpotent chiral scalar curvature. The bosonic part of this theory describes a massless scalaron and a massive axion in a de Sitter Universe.

Short Form of Weinstein Noise Sensitivity Scale (NSS-SF): Reliability, Validity and Gender Invariance among Chinese Individuals.

Science.gov (United States)

Zhong, Tao; Chung, Pak-Kwong; Liu, Jing Dong

2018-02-01

Independent from noise exposure, noise sensitivity plays a pivotal role in people's noise annoyance perception and concomitant health deteriorations. The present study empirically investigated the psychometric properties of the Chinese version of the Weinstein Noise Sensitivity Scale-Short Form (CNSS-SF), the widely used inventory measuring individual differences in noise perception. In total, 373 Chinese participants (age = 21.41 ± 3.36) completed the online, anonymous questionnaire package. Examination of the CNSS-SF's reliability (internal consistency), factorial validity through validation and cross-validation, nomological validity and measurement invariance across gender groups were undertaken. The Cronbach alpha coefficients and composite reliabilities indicated sufficient reliability of the CNSS-SF. Two confirmatory factor analyses (CFA), in two randomly partitioned groups of participants, substantiated the factorial validity of the scale. The nomological validity of the scale was also corroborated by the significant positive association of its score with the trait anxiety score. Measurement invariance of the CNSS-SF was also found across genders via multi-group CFA. Though not without limitations, findings from the present research provide promising evidence for the utility of the scale in measuring noise sensitivity among the Chinese population. The availability of the CNSS-SF can promote research related to environmental noise and health in China, as well as facilitate cross-cultural comparisons. Copyright © 2018 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

A Survey on Mixed Spin P-Fields

Institute of Scientific and Technical Information of China (English)

Huai-Liang CHANG; Jun LI; Wei-Ping LI; Chiu-Chu Melissa LIU

2017-01-01

The mixed spin P-fields (MSP for short) theory sets up a geometric platform to relate Gromov-Witten invariants of the quintic three-fold and Fan-Jarvis-Ruan-Witten invariants of the quintic polynomial in five variables.It starts with Wittens vision and the P-fields treatment of GW invariants and FJRW invariants.Then it briefly discusses the master space technique and its application to the set-up of the MSP moduli.Some key results in MSP theory are explained and some examples are provided.

Recent results of high p(T) physics at the CDF II

Energy Technology Data Exchange (ETDEWEB)

Tsuno, Soushi; /Okayama U.

2005-02-01

The Tevatron Run II program has been in progress since 2001. The CDF experiment has accumulated roughly five times as much data as did Run I, with much improved detectors. Preliminary results from the CDF experiment are presented. The authors focus on recent high p{sub T} physics results in the Tevatron Run II program.

Structure of the P{sub II} signal transduction protein of Neisseria meningitidis at 1.85 Å resolution

Energy Technology Data Exchange (ETDEWEB)

Nichols, Charles E. [Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Sainsbury, Sarah; Berrow, Nick S.; Alderton, David [The Oxford Protein Production Facility, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Saunders, Nigel J. [The Bacterial Pathogenesis and Functional Genomics Group, The Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE (United Kingdom); Stammers, David K. [Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); The Oxford Protein Production Facility, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Owens, Raymond J., E-mail: ray@strubi.ox.ac.uk [The Oxford Protein Production Facility, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Division of Structural Biology, Henry Wellcome Building for Genomic Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom)

2006-06-01

The structure of the P{sub II} signal transduction protein of N. meningitidis at 1.85 Å resolution is described. The P{sub II} signal transduction proteins GlnB and GlnK are implicated in the regulation of nitrogen assimilation in Escherichia coli and other enteric bacteria. P{sub II}-like proteins are widely distributed in bacteria, archaea and plants. In contrast to other bacteria, Neisseria are limited to a single P{sub II} protein (NMB 1995), which shows a high level of sequence identity to GlnB and GlnK from Escherichia coli (73 and 62%, respectively). The structure of the P{sub II} protein from N. meningitidis (serotype B) has been solved by molecular replacement to a resolution of 1.85 Å. Comparison of the structure with those of other P{sub II} proteins shows that the overall fold is tightly conserved across the whole population of related proteins, in particular the positions of the residues implicated in ATP binding. It is proposed that the Neisseria P{sub II} protein shares functions with GlnB/GlnK of enteric bacteria.

From modular invariants to graphs: the modular splitting method

International Nuclear Information System (INIS)

Isasi, E; Schieber, G

2007-01-01

We start with a given modular invariant M of a two-dimensional su-hat(n) k conformal field theory (CFT) and present a general method for solving the Ocneanu modular splitting equation and then determine, in a step-by-step explicit construction (1) the generalized partition functions corresponding to the introduction of boundary conditions and defect lines; (2) the quantum symmetries of the higher ADE graph G associated with the initial modular invariant M. Note that one does not suppose here that the graph G is already known, since it appears as a by-product of the calculations. We analyse several su-hat(3) k exceptional cases at levels 5 and 9

Type III secretion system and virulence markers highlight similarities and differences between human- and plant-associated pseudomonads related to Pseudomonas fluorescens and P. putida.

Science.gov (United States)

Mazurier, Sylvie; Merieau, Annabelle; Bergeau, Dorian; Decoin, Victorien; Sperandio, Daniel; Crépin, Alexandre; Barbey, Corinne; Jeannot, Katy; Vicré-Gibouin, Maïté; Plésiat, Patrick; Lemanceau, Philippe; Latour, Xavier

2015-04-01

Pseudomonas fluorescens is commonly considered a saprophytic rhizobacterium devoid of pathogenic potential. Nevertheless, the recurrent isolation of strains from clinical human cases could indicate the emergence of novel strains originating from the rhizosphere reservoir, which could be particularly resistant to the immune system and clinical treatment. The importance of type three secretion systems (T3SSs) in the related Pseudomonas aeruginosa nosocomial species and the occurrence of this secretion system in plant-associated P. fluorescens raise the question of whether clinical isolates may also harbor T3SSs. In this study, isolates associated with clinical infections and identified in hospitals as belonging to P. fluorescens were compared with fluorescent pseudomonads harboring T3SSs isolated from plants. Bacterial isolates were tested for (i) their genetic relationships based on their 16S rRNA phylogeny, (ii) the presence of T3SS genes by PCR, and (iii) their infectious potential on animals and plants under environmental or physiological temperature conditions. Two groups of bacteria were delineated among the clinical isolates. The first group encompassed thermotolerant (41°C) isolates from patients suffering from blood infections; these isolates were finally found to not belong to P. fluorescens but were closely related and harbored highly conserved T3SS genes belonging to the Ysc-T3SS family, like the T3SSs from P. aeruginosa. The second group encompassed isolates from patients suffering from cystic fibrosis; these isolates belonged to P. fluorescens and harbored T3SS genes belonging to the Hrp1-T3SS family found commonly in plant-associated P. fluorescens. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Recent progress in invariant pattern recognition

Science.gov (United States)

Arsenault, Henri H.; Chang, S.; Gagne, Philippe; Gualdron Gonzalez, Oscar

1996-12-01

We present some recent results in invariant pattern recognition, including methods that are invariant under two or more distortions of position, orientation and scale. There are now a few methods that yield good results under changes of both rotation and scale. Some new methods are introduced. These include locally adaptive nonlinear matched filters, scale-adapted wavelet transforms and invariant filters for disjoint noise. Methods using neural networks will also be discussed, including an optical method that allows simultaneous classification of multiple targets.

Finite type invariants and fatgraphs

DEFF Research Database (Denmark)

Andersen, Jørgen Ellegaard; Bene, Alex; Meilhan, Jean-Baptiste Odet Thierry

2010-01-01

–Murakami–Ohtsuki of the link invariant of Andersen–Mattes–Reshetikhin computed relative to choices determined by the fatgraph G; this provides a basic connection between 2d geometry and 3d quantum topology. For each fixed G, this invariant is shown to be universal for homology cylinders, i.e., G establishes an isomorphism...

Ermakov–Lewis invariants and Reid systems

Energy Technology Data Exchange (ETDEWEB)

Mancas, Stefan C., E-mail: stefan.mancas@erau.edu [Department of Mathematics, Embry-Riddle Aeronautical University, Daytona Beach, FL 32114-3900 (United States); Rosu, Haret C., E-mail: hcr@ipicyt.edu.mx [IPICyT, Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la presa San José 2055, Col. Lomas 4a Sección, 78216 San Luis Potosí, S.L.P. (Mexico)

2014-06-13

Reid's mth-order generalized Ermakov systems of nonlinear coupling constant α are equivalent to an integrable Emden–Fowler equation. The standard Ermakov–Lewis invariant is discussed from this perspective, and a closed formula for the invariant is obtained for the higher-order Reid systems (m≥3). We also discuss the parametric solutions of these systems of equations through the integration of the Emden–Fowler equation and present an example of a dynamical system for which the invariant is equivalent to the total energy. - Highlights: • Reid systems of order m are connected to Emden–Fowler equations. • General expressions for the Ermakov–Lewis invariants both for m=2 and m≥3 are obtained. • Parametric solutions of the Emden–Fowler equations related to Reid systems are obtained.

Scale-invariance underlying the logistic equation and its social applications

Energy Technology Data Exchange (ETDEWEB)

Hernando, A., E-mail: alberto.hernando@irsamc.ups-tlse.fr [Laboratoire Collisions, Agrégats, Réactivité, IRSAMC, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 09 (France); Plastino, A., E-mail: plastino@fisica.unlp.edu.ar [National University La Plata, IFLP-CCT-CONICET, C.C. 727, 1900 La Plata (Argentina); Universitat de les Illes Balears and IFISC-CSIC, 07122 Palma de Mallorca (Spain)

2013-01-03

On the basis of dynamical principles we i) advance a derivation of the Logistic Equation (LE), widely employed (among multiple applications) in the simulation of population growth, and ii) demonstrate that scale-invariance and a mean-value constraint are sufficient and necessary conditions for obtaining it. We also generalize the LE to multi-component systems and show that the above dynamical mechanisms underlie a large number of scale-free processes. Examples are presented regarding city-populations, diffusion in complex networks, and popularity of technological products, all of them obeying the multi-component logistic equation in an either stochastic or deterministic way.

Rotational Invariance of the 2d Spin - Spin Correlation Function

Science.gov (United States)

Pinson, Haru

2012-09-01

At the critical temperature in the 2d Ising model on the square lattice, we establish the rotational invariance of the spin-spin correlation function using the asymptotics of the spin-spin correlation function along special directions (McCoy and Wu in the two dimensional Ising model. Harvard University Press, Cambridge, 1973) and the finite difference Hirota equation for which the spin-spin correlation function is shown to satisfy (Perk in Phys Lett A 79:3-5, 1980; Perk in Proceedings of III international symposium on selected topics in statistical mechanics, Dubna, August 22-26, 1984, JINR, vol II, pp 138-151, 1985).

Scale-invariance underlying the logistic equation and its social applications

International Nuclear Information System (INIS)

Hernando, A.; Plastino, A.

2013-01-01

On the basis of dynamical principles we i) advance a derivation of the Logistic Equation (LE), widely employed (among multiple applications) in the simulation of population growth, and ii) demonstrate that scale-invariance and a mean-value constraint are sufficient and necessary conditions for obtaining it. We also generalize the LE to multi-component systems and show that the above dynamical mechanisms underlie a large number of scale-free processes. Examples are presented regarding city-populations, diffusion in complex networks, and popularity of technological products, all of them obeying the multi-component logistic equation in an either stochastic or deterministic way.

Search for high-mass resonances decaying to eμ in p$\\bar{p}$ collisions at √s = 1.96 TeV

Energy Technology Data Exchange (ETDEWEB)

Hahn, Kristian Allan [Univ. of Pennsylvania, Philadelphia, PA (United States)

2006-01-01

We describe a general search for resonances decaying to a neutral eμ final state in p$\\bar{p}$ collisions at a center-of-mass energy of 1.96 TeV. Using a data sample representing 344 pb^-1 of integrated luminosity recorded by the CDF II experiment, we compare Standard Model predictions with the number of observed events for invariant masses between 50 and 800 GeV/c². Finding no significant excess (5 events observed vs. 7.7 ± 0.8 expected for M_eμ > 100 GeV/c²), we set limits on sneutrino and Z' masses as functions of lepton family number violating couplings.

Time-scale invariances in preseismic electromagnetic radiation, magnetization and damage evolution of rocks

Directory of Open Access Journals (Sweden)

Y. Kawada

2007-10-01

Full Text Available We investigate the time-scale invariant changes in electromagnetic and mechanical energy releases prior to a rock failure or a large earthquake. The energy release processes are caused by damage evolutions such as crack propagation, motion of charged dislocation, area-enlargement of sheared asperities and repetitive creep-rate changes. Damage mechanics can be used to represent the time-scale invariant evolutions of both brittle and plastic damages. Irreversible thermodynamics applied to the damage mechanics reveals that the damage evolution produces the variations in charge, dipole and electromagnetic signals in addition to mechanical energy release, and yields the time-scale invariant patterns of Benioff electromagnetic radiation and cumulative Benioff strain-release. The irreversible thermodynamic framework of damage mechanics is also applicable to the seismo-magnetic effect, and the time-scale invariance is recognized in the remanent magnetization change associated with damage evolution prior to a rock failure.

Conformal invariance in the long-range Ising model

Directory of Open Access Journals (Sweden)

Miguel F. Paulos

2016-01-01

Full Text Available We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for the enhancement of scale invariance to conformal invariance. We however show that several correlation functions, computed to second order in the epsilon expansion, are nontrivially consistent with conformal invariance. We proceed to give a proof of conformal invariance to all orders in the epsilon expansion, based on the description of the long-range Ising model as a defect theory in an auxiliary higher-dimensional space. A detailed review of conformal invariance in the d-dimensional short-range Ising model is also included and may be of independent interest.

Conformal Invariance in the Long-Range Ising Model

CERN Document Server

Paulos, Miguel F; van Rees, Balt C; Zan, Bernardo

2016-01-01

We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for the enhancement of scale invariance to conformal invariance. We however show that several correlation functions, computed to second order in the epsilon expansion, are nontrivially consistent with conformal invariance. We proceed to give a proof of conformal invariance to all orders in the epsilon expansion, based on the description of the long-range Ising model as a defect theory in an auxiliary higher-dimensional space. A detailed review of conformal invariance in the d-dimensional short-range Ising model is also included and may be of independent interest.

Conformal invariance in the long-range Ising model

Energy Technology Data Exchange (ETDEWEB)

Paulos, Miguel F. [CERN, Theory Group, Geneva (Switzerland); Rychkov, Slava, E-mail: slava.rychkov@lpt.ens.fr [CERN, Theory Group, Geneva (Switzerland); Laboratoire de Physique Théorique de l' École Normale Supérieure (LPTENS), Paris (France); Faculté de Physique, Université Pierre et Marie Curie (UPMC), Paris (France); Rees, Balt C. van [CERN, Theory Group, Geneva (Switzerland); Zan, Bernardo [Institute of Physics, Universiteit van Amsterdam, Amsterdam (Netherlands)

2016-01-15

We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for the enhancement of scale invariance to conformal invariance. We however show that several correlation functions, computed to second order in the epsilon expansion, are nontrivially consistent with conformal invariance. We proceed to give a proof of conformal invariance to all orders in the epsilon expansion, based on the description of the long-range Ising model as a defect theory in an auxiliary higher-dimensional space. A detailed review of conformal invariance in the d-dimensional short-range Ising model is also included and may be of independent interest.

A many-particle adiabatic invariant of strongly magnetized pure electron plasmas

International Nuclear Information System (INIS)

Hjorth, P.G.

1988-01-01

A pure electron plasma is said to be strongly magnetized if the cyclotron radius of the electrons is much smaller than the classical distance of closest approach. In this parameter regime a many-particle adiabatic invariant constrains the collisional dynamics. For the case of a uniform magnetic field, the adiabatic invariant is the total kinetic energy associated with the electron velocity components that are perpendicular to the magnetic field (i.e., Σ j mv 2 j perpendicular/2). Were the adiabatic invariant an exact constant of the motion, no exchange of energy would be possible between the parallel and the perpendicular degrees of freedom, and the plasma could develop and maintain two different temperatures T parallel and T perpendicular. An adiabatic invariant, however, is not strictly conserved. In the present case, each collision produces an exponentially small exchange of energy between the parallel and the perpendicular degrees of freedom, and these act cumulatively in such a way that T parallel and T perpendicular eventually relax to a common value. The rate of equilibrium is calculated, both in the case where the collisions are described by classical mechanics and in the case where the collisions are described by quantum mechanics, the two calculations giving essentially the same result. A molecular dynamics simulation has been carried out, verifying the existence of this unusual invariant, and verifying the theoretically predicted rate equation

Modulating p-hydroxycinnamate behavior as a ditopic linker or photoacid in copper(ii) complexes with an auxiliary pyridine ligand.

Science.gov (United States)

Soldevila-Sanmartín, Joan; Calvet, Teresa; Font-Bardia, Merce; Domingo, Concepción; Ayllón, José A; Pons, Josefina

2018-05-08

The reaction of copper(ii) acetate monohydrate with p-hydroxycinnamic acid (HpOHcinn) and different pyridine derivatives (4-tert-butylpyridine, 4-tBupy; 4-acetylpyridine, 4-Acpy; 3-phenylpyridine, 3-Phpy; 4-phenylpyridine, 4-Phpy) was essayed in methanol solvent at room temperature. The crystal structures of the resulting compounds were elucidated. Their analysis shows that the choice of pyridine ligands determines different coordination modes of the pOHcinn ligand and the Cu(ii) coordination, nuclearity and geometry. The pOHcinn acts as a monodentate carboxylate ligand in combination with 4-tBupy or 4-Phpy, yielding monomers and dimers, associated by hydrogen bonds into supramolecular networks in which the phenol group plays a key role. Conversely, in combination with 4-Acpy or 3-Phpy, the phenol group coordinates directly to the Cu(ii), acting as a ditopic ligand and yielding 2D coordination polymers. The compound containing 3-Phpy shows interesting MeOH-H2O reversible exchange behavior. Not only has the pyridine auxiliary ligand had a tremendous effect on the coordination mode of pOHcinn, but also its reactivity is influenced. Particularly, in the case of the compound containing 4-Phpy, it undergoes a photoinduced process, in which the phenol group deprotonates and coordinates to Cu(ii) as a phenoxy ligand. This yields a coordination polymer in which two different dimers alternate, bridged by the resulting pOcinn ligand. The magneto-structural correlation of this compound is also discussed.

BRDF invariant stereo using light transport constancy.

Science.gov (United States)

Wang, Liang; Yang, Ruigang; Davis, James E

2007-09-01

Nearly all existing methods for stereo reconstruction assume that scene reflectance is Lambertian and make use of brightness constancy as a matching invariant. We introduce a new invariant for stereo reconstruction called light transport constancy (LTC), which allows completely arbitrary scene reflectance (bidirectional reflectance distribution functions (BRDFs)). This invariant can be used to formulate a rank constraint on multiview stereo matching when the scene is observed by several lighting configurations in which only the lighting intensity varies. In addition, we show that this multiview constraint can be used with as few as two cameras and two lighting configurations. Unlike previous methods for BRDF invariant stereo, LTC does not require precisely configured or calibrated light sources or calibration objects in the scene. Importantly, the new constraint can be used to provide BRDF invariance to any existing stereo method whenever appropriate lighting variation is available.

Observation of $S=+1$ Narrow Resonances in the System $pK^0_s$ from $p+\\rm {C_3H_8}$ Collision at 10 GeV/$c$

CERN Document Server

Aslanyan, P Zh; Rikhvitskaya, G G

2004-01-01

Experimental data from a 2 m propane bubble chamber have been analyzed to search for an exotic baryon state, the $\\Theta^+$ baryon, in the $pK^0_s$ decay mode for the reaction $p+{\\rm C_3H_8}$ at 10 GeV/$c$. The $pK^0_s$ invariant mass spectrum shows resonant structures with $M_{p K_s^0}=1540\\pm 8$, $1613\\pm10$, $1821\\pm11$ MeV/$c^2$ and $\\Gamma_{p K_s^0}= 9.2\\pm1.8$, $16.1\\pm4.1$, $28.0\\pm9.4$ MeV/$c^2$. The statistical significance of these peaks has been estimated as $5.5$, $4.8$ and $5.0$ s.d., respectively. There are also small peaks in mass regions of 1487 (3.0 s.d.), 1690 (3.6 s.d.) and 1980 (3.0 s.d.) MeV/$c^2$.

A scale invariance criterion for LES parametrizations

Directory of Open Access Journals (Sweden)

Urs Schaefer-Rolffs

2015-01-01

Full Text Available Turbulent kinetic energy cascades in fluid dynamical systems are usually characterized by scale invariance. However, representations of subgrid scales in large eddy simulations do not necessarily fulfill this constraint. So far, scale invariance has been considered in the context of isotropic, incompressible, and three-dimensional turbulence. In the present paper, the theory is extended to compressible flows that obey the hydrostatic approximation, as well as to corresponding subgrid-scale parametrizations. A criterion is presented to check if the symmetries of the governing equations are correctly translated into the equations used in numerical models. By applying scaling transformations to the model equations, relations between the scaling factors are obtained by demanding that the mathematical structure of the equations does not change.The criterion is validated by recovering the breakdown of scale invariance in the classical Smagorinsky model and confirming scale invariance for the Dynamic Smagorinsky Model. The criterion also shows that the compressible continuity equation is intrinsically scale-invariant. The criterion also proves that a scale-invariant turbulent kinetic energy equation or a scale-invariant equation of motion for a passive tracer is obtained only with a dynamic mixing length. For large-scale atmospheric flows governed by the hydrostatic balance the energy cascade is due to horizontal advection and the vertical length scale exhibits a scaling behaviour that is different from that derived for horizontal length scales.

Radiative proton-deuteron capture in a gauge invariant relativistic model

NARCIS (Netherlands)

Korchin, AY; Van Neck, D; Scholten, O; Waroquier, M

A relativistic model is developed for the description of the process p+dHe-3+gamma*. It is based on the impulse approximation, but is explicitly gauge invariant and Lorentz covariant. The model is applied to radiative proton-deuteron capture and electrodisintegration of He-3 nt intermediate

Solid-state nuclear magnetic resonance (NMR) spectroscopy of human immunodeficiency virus gp41 protein that includes the fusion peptide: NMR detection of recombinant Fgp41 in inclusion bodies in whole bacterial cells and structural characterization of purified and membrane-associated Fgp41.

Science.gov (United States)

Vogel, Erica P; Curtis-Fisk, Jaime; Young, Kaitlin M; Weliky, David P

2011-11-22

Human immunodeficiency virus (HIV) infection of a host cell begins with fusion of the HIV and host cell membranes and is mediated by the gp41 protein, a single-pass integral membrane protein of HIV. The 175 N-terminal residues make up the ectodomain that lies outside the virus. This work describes the production and characterization of an ectodomain construct containing the 154 N-terminal gp41 residues, including the fusion peptide (FP) that binds to target cell membranes. The Fgp41 sequence was derived from one of the African clade A strains of HIV-1 that have been less studied than European/North American clade B strains. Fgp41 expression at a level of ~100 mg/L of culture was evidenced by an approach that included amino acid type (13)CO and (15)N labeling of recombinant protein and solid-state NMR (SSNMR) spectroscopy of lyophilized whole cells. The approach did not require any protein solubilization or purification and may be a general approach for detection of recombinant protein. The purified Fgp41 yield was ~5 mg/L of culture. SSNMR spectra of membrane-associated Fgp41 showed high helicity for the residues C-terminal of the FP. This was consistent with a "six-helix bundle" (SHB) structure that is the final gp41 state during membrane fusion. This observation and negligible Fgp41-induced vesicle fusion supported a function for SHB gp41 of membrane stabilization and fusion arrest. SSNMR spectra of residues in the membrane-associated FP provided evidence of a mixture of molecular populations with either helical or β-sheet FP conformation. These and earlier SSNMR data strongly support the existence of these populations in the SHB state of membrane-associated gp41. © 2011 American Chemical Society

Comments on a direct approach to finding exact invariants for one-dimensional time-dependent classical hamiltonian

International Nuclear Information System (INIS)

Castro Moreira, I. de.

1983-01-01

A method introduced by Lewis and Leach for the obtention of exact invariants of the form I = Σ p sup(n) F sub(n) (q,t) for hamiltonian systems, is generalized and applied directly on the equations of motion. It gives us a general procedure to generates exact invariants also for non hamiltonian systems. (Author) [pt

Gauge-invariant factorization and canonical quantization of topologically massive gauge theories in any dimension

International Nuclear Information System (INIS)

Bertrand, Bruno; Govaerts, Jan

2007-01-01

Abelian topologically massive gauge theories (TMGT) provide a topological mechanism to generate mass for a bosonic p-tensor field in any spacetime dimension. These theories include the (2+1)-dimensional Maxwell-Chern-Simons and (3+1)-dimensional Cremmer-Scherk actions as particular cases. Within the Hamiltonian formulation, the embedded topological field theory (TFT) sector related to the topological mass term is not manifest in the original phase space. However, through an appropriate canonical transformation, a gauge-invariant factorization of phase space into two orthogonal sectors is feasible. The first of these sectors includes canonically conjugate gauge-invariant variables with free massive excitations. The second sector, which decouples from the total Hamiltonian, is equivalent to the phase-space description of the associated non-dynamical pure TFT. Within canonical quantization, a likewise factorization of quantum states thus arises for the full spectrum of TMGT in any dimension. This new factorization scheme also enables a definition of the usual projection from TMGT onto topological quantum field theories in a most natural and transparent way. None of these results rely on any gauge-fixing procedure whatsoever

Construction of time-dependent dynamical invariants: A new approach

International Nuclear Information System (INIS)

Bertin, M. C.; Pimentel, B. M.; Ramirez, J. A.

2012-01-01

We propose a new way to obtain polynomial dynamical invariants of the classical and quantum time-dependent harmonic oscillator from the equations of motion. We also establish relations between linear and quadratic invariants, and discuss how the quadratic invariant can be related to the Ermakov invariant.

Wavelet-based moment invariants for pattern recognition

Science.gov (United States)

Chen, Guangyi; Xie, Wenfang

2011-07-01

Moment invariants have received a lot of attention as features for identification and inspection of two-dimensional shapes. In this paper, two sets of novel moments are proposed by using the auto-correlation of wavelet functions and the dual-tree complex wavelet functions. It is well known that the wavelet transform lacks the property of shift invariance. A little shift in the input signal will cause very different output wavelet coefficients. The autocorrelation of wavelet functions and the dual-tree complex wavelet functions, on the other hand, are shift-invariant, which is very important in pattern recognition. Rotation invariance is the major concern in this paper, while translation invariance and scale invariance can be achieved by standard normalization techniques. The Gaussian white noise is added to the noise-free images and the noise levels vary with different signal-to-noise ratios. Experimental results conducted in this paper show that the proposed wavelet-based moments outperform Zernike's moments and the Fourier-wavelet descriptor for pattern recognition under different rotation angles and different noise levels. It can be seen that the proposed wavelet-based moments can do an excellent job even when the noise levels are very high.

Search for high-mass resonances decaying to e mu in p anti-p collisions at s**(1/2) = 1.96-TeV

Energy Technology Data Exchange (ETDEWEB)

Abulencia, A.; Acosta, D.; Adelman, Jahred A.; Affolder, T.; Akimoto, T.; Albrow, M.G.; Ambrose, D.; Amerio, S.; Amidei, D.; Anastassov, A.; Anikeev, K.; /Taiwan, Inst.

2006-03-01

The authors describe a general search for resonances decaying to a neutral e{mu} final state in p{bar p} collisions at a center-of-mass energy of 1.96 TeV. Using a data sample representing 344 pb{sup -1} of integrated luminosity recorded by the CDF II experiment, they compare Standard Model predictions with the number of observed events for invariant masses between 50 and 800 GeV/c{sup 2}. Finding no significant excess (5 events observed vs. 7.7 {+-} 0.8 expected for M{sub e{mu}} > 100 GeV/c{sup 2}), they set limits on sneutrino and Z{prime} masses as functions of lepton family number violating couplings.

Wilson loop invariants from WN conformal blocks

Directory of Open Access Journals (Sweden)

Oleg Alekseev

2015-12-01

Full Text Available Knot and link polynomials are topological invariants calculated from the expectation value of loop operators in topological field theories. In 3D Chern–Simons theory, these invariants can be found from crossing and braiding matrices of four-point conformal blocks of the boundary 2D CFT. We calculate crossing and braiding matrices for WN conformal blocks with one component in the fundamental representation and another component in a rectangular representation of SU(N, which can be used to obtain HOMFLY knot and link invariants for these cases. We also discuss how our approach can be generalized to invariants in higher-representations of WN algebra.

Invariants of triangular Lie algebras

International Nuclear Information System (INIS)

Boyko, Vyacheslav; Patera, Jiri; Popovych, Roman

2007-01-01

Triangular Lie algebras are the Lie algebras which can be faithfully represented by triangular matrices of any finite size over the real/complex number field. In the paper invariants ('generalized Casimir operators') are found for three classes of Lie algebras, namely those which are either strictly or non-strictly triangular, and for so-called special upper triangular Lie algebras. Algebraic algorithm of Boyko et al (2006 J. Phys. A: Math. Gen.39 5749 (Preprint math-ph/0602046)), developed further in Boyko et al (2007 J. Phys. A: Math. Theor.40 113 (Preprint math-ph/0606045)), is used to determine the invariants. A conjecture of Tremblay and Winternitz (2001 J. Phys. A: Math. Gen.34 9085), concerning the number of independent invariants and their form, is corroborated

INFLUENCIA DEL pH SOBRE LA ADSORCIÓN EN CARBÓN ACTIVADO DE Cd(II) Y Ni(II) DESDE SOLUCIONES ACUOSAS

OpenAIRE

Paola Rodríguez; Liliana Giraldo; Juan Carlos Moreno

2011-01-01

La adsorción de iones Cd(II) y Ni(II) desde soluciones acuosas sobre carbón activado se estudia con diferentes valores de pH. La adsorción de los iones se realiza en dos condiciones de pH de la solución: en la primera el pH varía en el transcurso del proceso a medida que los iones se adsorben y en la segunda el pH se mantiene fijo durante la adsorción. Cuando no se realiza un control en el pH de la solución se observan incrementos en la concentración de los io...

Angiotensin II stimulates basolateral 50-pS K channels in the thick ascending limb.

Science.gov (United States)

Wang, Mingxiao; Luan, Haiyan; Wu, Peng; Fan, Lili; Wang, Lijun; Duan, Xinpeng; Zhang, Dandan; Wang, Wen-Hui; Gu, Ruimin

2014-03-01

We used the patch-clamp technique to examine the effect of angiotensin II (ANG II) on the basolateral K channels in the thick ascending limb (TAL) of the rat kidney. Application of ANG II increased the channel activity and the current amplitude of the basolateral 50-pS K channel. The stimulatory effect of ANG II on the K channels was completely abolished by losartan, an inhibitor of type 1 angiotensin receptor (AT1R), but not by PD123319, an AT2R antagonist. Moreover, inhibition of phospholipase C (PLC) and protein kinase C (PKC) also abrogated the stimulatory effect of ANG II on the basolateral K channels in the TAL. This suggests that the stimulatory effect of ANG II on the K channels was induced by activating PLC and PKC pathways. Western blotting demonstrated that ANG II increased the phosphorylation of c-Src at tyrosine residue 416, an indication of c-Src activation. This effect was mimicked by PKC stimulator but abolished by calphostin C. Moreover, inhibition of NADPH oxidase (NOX) also blocked the effect of ANG II on c-Src tyrosine phosphorylation. The role of Src-family protein tyrosine kinase (SFK) in mediating the effect of ANG II on the basolateral K channel was further suggested by the experiments in which inhibition of SFK abrogated the stimulatory effect of ANG II on the basolateral 50-pS K channel. We conclude that ANG II increases basolateral 50-pS K channel activity via AT1R and that activation of AT1R stimulates SFK by a PLC-PKC-NOX-dependent mechanism.

Intra-Hepatic Depletion of Mucosal-Associated Invariant T Cells in Hepatitis C Virus-Induced Liver Inflammation.

Science.gov (United States)

Bolte, Fabian J; O'Keefe, Ashley C; Webb, Lauren M; Serti, Elisavet; Rivera, Elenita; Liang, T Jake; Ghany, Marc; Rehermann, Barbara

2017-11-01

Chronic hepatitis affects phenotypes of innate and adaptive immune cells. Mucosal-associated invariant T (MAIT) cells are enriched in the liver as compared with the blood, respond to intra-hepatic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated from the gut. Little is known about the role of MAIT cells in livers of patients with chronic hepatitis C virus (HCV) infection and their fate after antiviral therapy. We collected blood samples from 42 patients with chronic HCV infection who achieved a sustained virologic response after 12 weeks of treatment with sofosbuvir and velpatasvir. Mononuclear cells were isolated from blood before treatment, at weeks 4 and 12 during treatment, and 24 weeks after the end of treatment. Liver biopsies were collected from 37 of the patients prior to and at week 4 of treatment. Mononuclear cells from 56 blood donors and 10 livers that were not suitable for transplantation were used as controls. Liver samples were assessed histologically for inflammation and fibrosis. Mononuclear cells from liver and blood were studied by flow cytometry and analyzed for responses to cytokine and bacterial stimulation. The frequency of MAIT cells among T cells was significantly lower in blood and liver samples of patients with HCV infection than of controls (median, 1.31% vs 2.32% for blood samples, P = .0048; and median, 4.34% vs 13.40% for liver samples, P = .001). There was an inverse correlation between the frequency of MAIT cells in the liver and histologically determined levels of liver inflammation (r = -.5437, P = .0006) and fibrosis (r = -.5829, P = .0002). MAIT cells from the liver had higher levels of activation and cytotoxicity than MAIT cells from blood (P liver inflammation and MAIT cell activation and cytotoxicity, and increased the MAIT cell frequency among intra-hepatic but not blood T cells. The MAIT cell response to T-cell receptor-mediated stimulation did not change during the 12 weeks of

Real-time pose invariant logo and pattern detection

Science.gov (United States)

Sidla, Oliver; Kottmann, Michal; Benesova, Wanda

2011-01-01

The detection of pose invariant planar patterns has many practical applications in computer vision and surveillance systems. The recognition of company logos is used in market studies to examine the visibility and frequency of logos in advertisement. Danger signs on vehicles could be detected to trigger warning systems in tunnels, or brand detection on transport vehicles can be used to count company-specific traffic. We present the results of a study on planar pattern detection which is based on keypoint detection and matching of distortion invariant 2d feature descriptors. Specifically we look at the keypoint detectors of type: i) Lowe's DoG approximation from the SURF algorithm, ii) the Harris Corner Detector, iii) the FAST Corner Detector and iv) Lepetit's keypoint detector. Our study then compares the feature descriptors SURF and compact signatures based on Random Ferns: we use 3 sets of sample images to detect and match 3 logos of different structure to find out which combinations of keypoint detector/feature descriptors work well. A real-world test tries to detect vehicles with a distinctive logo in an outdoor environment under realistic lighting and weather conditions: a camera was mounted on a suitable location for observing the entrance to a parking area so that incoming vehicles could be monitored. In this 2 hour long recording we can successfully detect a specific company logo without false positives.

Chern-Simons invariants on hyperbolic manifolds and topological quantum field theories

Energy Technology Data Exchange (ETDEWEB)

Bonora, L. [International School for Advanced Studies (SISSA/ISAS), Trieste (Italy); INFN, Sezione di Trieste (Italy); Bytsenko, A.A.; Goncalves, A.E. [Universidade Estadual de Londrina, Departamento de Fisica, Londrina-Parana (Brazil)

2016-11-15

We derive formulas for the classical Chern-Simons invariant of irreducible SU(n)-flat connections on negatively curved locally symmetric three-manifolds. We determine the condition for which the theory remains consistent (with basic physical principles). We show that a connection between holomorphic values of Selberg-type functions at point zero, associated with R-torsion of the flat bundle, and twisted Dirac operators acting on negatively curved manifolds, can be interpreted by means of the Chern-Simons invariant. On the basis of the Labastida-Marino-Ooguri-Vafa conjecture we analyze a representation of the Chern-Simons quantum partition function (as a generating series of quantum group invariants) in the form of an infinite product weighted by S-functions and Selberg-type functions. We consider the case of links and a knot and use the Rogers approach to discover certain symmetry and modular form identities. (orig.)

Action priors for learning domain invariances

CSIR Research Space (South Africa)

Rosman, Benjamin S

2015-04-01

Full Text Available behavioural invariances in the domain, by identifying actions to be prioritised in local contexts, invariant to task details. This information has the effect of greatly increasing the speed of solving new problems. We formalise this notion as action priors...

Interfacial charge separation and recombination in InP and quasi-type II InP/CdS core/shell quantum dot-molecular acceptor complexes.

Science.gov (United States)

Wu, Kaifeng; Song, Nianhui; Liu, Zheng; Zhu, Haiming; Rodríguez-Córdoba, William; Lian, Tianquan

2013-08-15

Recent studies of group II-VI colloidal semiconductor heterostuctures, such as CdSe/CdS core/shell quantum dots (QDs) or dot-in-rod nanorods, show that type II and quasi-type II band alignment can facilitate electron transfer and slow down charge recombination in QD-molecular electron acceptor complexes. To explore the general applicability of this wave function engineering approach for controlling charge transfer properties, we investigate exciton relaxation and dissociation dynamics in InP (a group III-V semiconductor) and InP/CdS core/shell (a heterostructure beween group III-V and II-VI semiconductors) QDs by transient absorption spectroscopy. We show that InP/CdS QDs exhibit a quasi-type II band alignment with the 1S electron delocalized throughout the core and shell and the 1S hole confined in the InP core. In InP-methylviologen (MV(2+)) complexes, excitons in the QD can be dissociated by ultrafast electron transfer to MV(2+) from the 1S electron level (with an average time constant of 11.4 ps) as well as 1P and higher electron levels (with a time constant of 0.39 ps), which is followed by charge recombination to regenerate the complex in its ground state (with an average time constant of 47.1 ns). In comparison, InP/CdS-MV(2+) complexes show similar ultrafast charge separation and 5-fold slower charge recombination rates, consistent with the quasi-type II band alignment in these heterostructures. This result demonstrates that wave function engineering in nanoheterostructures of group III-V and II-VI semiconductors provides a promising approach for optimizing their light harvesting and charge separation for solar energy conversion applications.

Reduction and long-term immobilization of technetium by Fe(II) associated with clay mineral nontronite

International Nuclear Information System (INIS)

Jaisi, Deb P.; Dong, Hailiang; Plymale, Andrew E.; Fredrickson, Jim K.; Zachara, John M.; Heald, S.; Liu, Chongxuan

2009-01-01

99Tc is formed mostly during nuclear reactions and is released into the environment during weapons testing and inadvertent waste disposal. The long half-life, high environmental mobility (as Tc(VII)O4-) and its possible uptake into the food chain cause 99Tc to be a significant environmental contaminant. In this study, we evaluated the role of Fe(II) in biologically reduced clay mineral, nontronite (NAu-2), in reducing Tc(VII)O4- to poorly soluble Tc(IV) species as a function of pH and Fe(II) concentration. The rate of Tc(VII) reduction by Fe(II) in NAu-2 was higher at neutral pH (pH 7.0) than at acidic and basic pHs when Fe(II) concentration was low (< 1 mmol/g). The effect of pH, however, was insignificant at higher Fe(II) concentrations. The reduction of Tc(VII) by Fe(II) associated with NAu-2 was also studied in the presence of common subsurface oxidants including iron and manganese oxides, nitrate, and oxygen, to evaluate the effect of the oxidants on the enhancement and inhibition of Tc(VII) reduction, and reoxidation of Tc(IV). Addition of iron oxides (goethite and hematite) to the Tc(VII)-NAu-2 system, where Tc(VII) reduction was ongoing, enhanced reduction of Tc(VII), apparently as a result of re-distribution of reactive Fe(II) from NAu-2 to more reactive goethite/hematite surfaces. Addition of manganese oxides stopped further Tc(VII) reduction, and in case of K+-birnessite, it reoxidized previously reduced Tc(IV). Nitrate neither enhanced reduction of Tc(VII) nor promoted reoxidation of Tc(IV). Approximately 11% of Tc(IV) was oxidized by oxygen. The rate and extent of Tc(IV) reoxidation was found to strongly depend on the nature of the oxidants and concentration of Fe(II). When the same oxidants were added to aged Tc reduction products (mainly NAu-2 and TcO2nH2O), the extent of Tc(IV) reoxidation decreased significantly relative to fresh Tc(IV) products. Increasing NAu-2 concentration also resulted in the decreased extent of Tc(IV) reoxidation. The results

Embedded graph invariants in Chern-Simons theory

International Nuclear Information System (INIS)

Major, Seth A.

1999-01-01

Chern-Simons gauge theory, since its inception as a topological quantum field theory, has proved to be a rich source of understanding for knot invariants. In this work the theory is used to explore the definition of the expectation value of a network of Wilson lines -- an embedded graph invariant. Using a generalization of the variational method, lowest-order results for invariants for graphs of arbitrary valence and general vertex tangent space structure are derived. Gauge invariant operators are introduced. Higher order results are found. The method used here provides a Vassiliev-type definition of graph invariants which depend on both the embedding of the graph and the group structure of the gauge theory. It is found that one need not frame individual vertices. However, without a global projection of the graph there is an ambiguity in the relation of the decomposition of distinct vertices. It is suggested that framing may be seen as arising from this ambiguity -- as a way of relating frames at distinct vertices

Anti-aggregation-based spectrometric detection of Hg(II) at physiological pH using gold nanorods

Energy Technology Data Exchange (ETDEWEB)

Rajeshwari, A.; Karthiga, D.; Chandrasekaran, Natarajan; Mukherjee, Amitava, E-mail: amit.mookerjea@gmail.com

2016-10-01

An efficient detection method for Hg (II) ions at physiological pH (pH 7.4) was developed using tween 20-modified gold nanorods (NRs) in the presence of dithiothreitol (DTT). Thiol groups (-SH) at the end of DTT have a higher affinity towards gold atoms, and they can covalently interact with gold NRs and leads to their aggregation. The addition of Hg(II) ions prevents the aggregation of gold NRs due to the covalent bond formation between the -SH group of DTT and Hg(II) ions in the buffer system. The changes in the longitudinal surface plasmon resonance peak of gold NRs were characterized using a UV–visible spectrophotometer. The absorption intensity peak of gold NRs at 679 nm was observed to reduce after interaction with DTT, and the absorption intensity was noted to increase by increasing the concentration of Hg(II) ions. The TEM analysis confirms the morphological changes of gold NRs before and after addition of Hg(II) ions in the presence of DTT. Further, the aggregation and disaggregation of gold NRs were confirmed by particle size and zeta potential analysis. The developed method shows an excellent linearity (y = 0.001 x + 0.794) for the graph plotted between the absorption ratio and Hg(II) concentration (1 to 100 pM) under the optimized conditions. The limit of detection was noted to be 0.42 pM in the buffer system. The developed method was tested in simulated body fluid, and it was found to have a good recovery rate. - Highlights: • Tween-20 modified gold NRs used as a probe for Hg(II) at physiological pH. • TEM, particle size and surface charge analysis confirm the aggregation and • disaggregation of NRs • The sensitivity of the probe for Hg(II) ions detection was 0.42 pM. • Hg(II) estimation in simulated body fluids with good recovery.

Relating measurement invariance, cross-level invariance, and multilevel reliability

NARCIS (Netherlands)

Jak, S.; Jorgensen, T.D.

2017-01-01

Data often have a nested, multilevel structure, for example when data are collected from children in classrooms. This kind of data complicate the evaluation of reliability and measurement invariance, because several properties can be evaluated at both the individual level and the cluster level, as

Conformal invariance and two-dimensional physics

International Nuclear Information System (INIS)

Zuber, J.B.

1993-01-01

Actually, physicists and mathematicians are very interested in conformal invariance: geometric transformations which keep angles. This symmetry is very important for two-dimensional systems as phase transitions, string theory or node mathematics. In this article, the author presents the conformal invariance and explains its usefulness

Pattern recognition: invariants in 3D

International Nuclear Information System (INIS)

Proriol, J.

1992-01-01

In e + e - events, the jets have a spherical 3D symmetry. A set of invariants are defined for 3D objects with a spherical symmetry. These new invariants are used to tag the number of jets in e + e - events. (K.A.) 3 refs

A test for ordinal measurement invariance

NARCIS (Netherlands)

Ligtvoet, R.; Millsap, R.E.; Bolt, D.M.; van der Ark, L.A.; Wang, W.-C.

2015-01-01

One problem with the analysis of measurement invariance is the reliance of the analysis on having a parametric model that accurately describes the data. In this paper an ordinal version of the property of measurement invariance is proposed, which relies only on nonparametric restrictions. This

Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance

DEFF Research Database (Denmark)

Nolsøe, R L; Hamid, Y H; Pociot, F

2006-01-01

-cells, Fas expression and concomitant apoptosis owing to a constitutive expression of FasL. FASL and FAS map to loci linked to type II diabetes and estimates of insulin resistance, respectively. We have tested two functional promoter polymorphisms, FAS-670 G>A and FASL-844C>T as well as a microsatellite...... association to type II diabetes for the allele distribution of the FASL microsatellite (P-value 0.02, Bonferroni corrected). The FAS-670G>A was associated with homeostasis model assessment insulin resistance index and body mass index (P-values 0.02 and 0.02). We conclude that polymorphisms of FASL and FAS...

A scale invariant covariance structure on jet space

DEFF Research Database (Denmark)

Pedersen, Kim Steenstrup; Loog, Marco; Markussen, Bo

2005-01-01

This paper considers scale invariance of statistical image models. We study statistical scale invariance of the covariance structure of jet space under scale space blurring and derive the necessary structure and conditions of the jet covariance matrix in order for it to be scale invariant. As par...

Inflation in a Scale Invariant Universe

Energy Technology Data Exchange (ETDEWEB)

Ferreira, Pedro G. [Oxford U.; Hill, Christopher T. [Fermilab; Noller, Johannes [Zurich U.; Ross, Graham G. [Oxford U., Theor. Phys.

2018-02-16

A scale-invariant universe can have a period of accelerated expansion at early times: inflation. We use a frame-invariant approach to calculate inflationary observables in a scale invariant theory of gravity involving two scalar fields - the spectral indices, the tensor to scalar ratio, the level of isocurvature modes and non-Gaussianity. We show that scale symmetry leads to an exact cancellation of isocurvature modes and that, in the scale-symmetry broken phase, this theory is well described by a single scalar field theory. We find the predictions of this theory strongly compatible with current observations.

Adiabatic invariants of the extended KdV equation

Energy Technology Data Exchange (ETDEWEB)

Karczewska, Anna [Faculty of Mathematics, Computer Science and Econometrics, University of Zielona Góra, Szafrana 4a, 65-246 Zielona Góra (Poland); Rozmej, Piotr, E-mail: p.rozmej@if.uz.zgora.pl [Institute of Physics, Faculty of Physics and Astronomy, University of Zielona Góra, Szafrana 4a, 65-246 Zielona Góra (Poland); Infeld, Eryk [National Centre for Nuclear Research, Hoża 69, 00-681 Warszawa (Poland); Rowlands, George [Department of Physics, University of Warwick, Coventry, CV4 7A (United Kingdom)

2017-01-30

When the Euler equations for shallow water are taken to the next order, beyond KdV, momentum and energy are no longer exact invariants. (The only one is mass.) However, adiabatic invariants (AI) can be found. When the KdV expansion parameters are zero, exact invariants are recovered. Existence of adiabatic invariants results from general theory of near-identity transformations (NIT) which allow us to transform higher order nonintegrable equations to asymptotically equivalent (when small parameters tend to zero) integrable form. Here we present a direct method of calculations of adiabatic invariants. It does not need a transformation to a moving reference frame nor performing a near-identity transformation. Numerical tests show that deviations of AI from constant values are indeed small. - Highlights: • We suggest a new and simple method for calculating adiabatic invariants of second order wave equations. • It is easy to use and we hope that it will be useful if published. • Interesting numerics included.

Zn(II, Mn(II and Sr(II Behavior in a Natural Carbonate Reservoir System. Part I: Impact of Salinity, Initial pH and Initial Zn(II Concentration in Atmospheric Conditions

Directory of Open Access Journals (Sweden)

Auffray B.

2016-07-01

Full Text Available The sorption of inorganic elements on carbonate minerals is well known in strictly controlled conditions which limit the impact of other phenomena such as dissolution and/or precipitation. In this study, we evidence the behavior of Zn(II (initially in solution and two trace elements, Mn(II and Sr(II (released by carbonate dissolution in the context of a leakage from a CO2 storage site. The initial pH chosen are either equal to the pH of the water-CO2 equilibrium (~ 2.98 or equal to the pH of the water-CO2-calcite system (~ 4.8 in CO2 storage conditions. From this initial influx of liquid, saturated or not with respect to calcite, the batch experiments evolve freely to their equilibrium, as it would occur in a natural context after a perturbation. The batch experiments are carried out on two natural carbonates (from Lavoux and St-Emilion with PCO2 = 10−3.5 bar, with different initial conditions ([Zn(II]i from 10−4 to 10−6 M, either with pure water or 100 g/L NaCl brine. The equilibrium regarding calcite dissolution is confirmed in all experiments, while the zinc sorption evidenced does not always correspond to the two-step mechanism described in the literature. A preferential sorption of about 10% of the concentration is evidenced for Mn(II in aqueous experiments, while Sr(II is more sorbed in saline conditions. This study also shows that this preferential sorption, depending on the salinity, is independent of the natural carbonate considered. Then, the simulations carried out with PHREEQC show that experiments and simulations match well concerning the equilibrium of dissolution and the sole zinc sorption, with log KZn(II ~ 2 in pure water and close to 4 in high salinity conditions. When the simulations were possible, the log K values for Mn(II and Sr(II were much different from those in the literature obtained by sorption in controlled conditions. It is shown that a new conceptual model regarding multiple Trace Elements (TE sorption is

Gromov-Witten invariants and localization

Science.gov (United States)

Morrison, David R.

2017-11-01

We give a pedagogical review of the computation of Gromov-Witten invariants via localization in 2D gauged linear sigma models. We explain the relationship between the two-sphere partition function of the theory and the Kähler potential on the conformal manifold. We show how the Kähler potential can be assembled from classical, perturbative, and non-perturbative contributions, and explain how the non-perturbative contributions are related to the Gromov-Witten invariants of the corresponding Calabi-Yau manifold. We then explain how localization enables efficient calculation of the two-sphere partition function and, ultimately, the Gromov-Witten invariants themselves. This is a contribution to the review issue ‘Localization techniques in quantum field theories’ (ed V Pestun and M Zabzine) which contains 17 chapters, available at [1].

Link invariant and $G_2$ web space

OpenAIRE

Sakamoto, Takuro; Yonezawa, Yasuyoshi

2017-01-01

In this paper, we reconstruct Kuperberg’s $G_2$ web space [5, 6]. We introduce a new web diagram (a trivalent graph with only double edges) and new relations between Kuperberg’s web diagrams and the new web diagram. Using the web diagrams, we give crossing formulas for the $R$-matrices associated to some irreducible representations of $U_q(G_2)$ and calculate $G_2$ quantum link invariants for generalized twist links.

A Fe(II)/citrate/UV/PMS process for carbamazepine degradation at a very low Fe(II)/PMS ratio and neutral pH: The mechanisms.

Science.gov (United States)

Ling, Li; Zhang, Dapeng; Fan, Chihhao; Shang, Chii

2017-11-01

A novel Fe(II)/citrate/UV/PMS process for degrading a model micropollutant, carbamazepine (CBZ), at a low Fe(II)/PMS ratio and neutral pH has been proposed in this study, and the mechanisms of radical generation in the system was explored. With a UV dose of 302.4 mJ/cm 2 , an initial pH of 7, and CBZ, PMS, Fe(II) and citrate at initial concentrations of 10, 100, 12 and 26 μM, respectively, the CBZ degradation efficiency reached 71% in 20 min in the Fe(II)/citrate/UV/PMS process, which was 4.7 times higher than that in either the citrate/UV/PMS or Fe(II)/citrate/PMS process. The enhanced CBZ degradation in the Fe(II)/citrate/UV/PMS process was mainly attributed to the continuous activation of PMS by the UV-catalyzed regenerated Fe(II) from a Fe(III)-citrate complex, [Fe 3 O(cit) 3 H 3 ] 2- , which not only maintained Fe(III) soluble at neutral pH, but also increased 6.6 and 2.6 times of its molar absorbance and quantum yield as compared to those of ionic Fe(III), respectively. In the Fe(II)/citrate/UV/PMS process, the SO 4 •- produced from the fast reaction between PMS and the initially-added Fe(II) contributed 11% of CBZ degradation. The PMS activation by the UV radiation and regenerated Fe(II) contributed additional 14% and 46% of CBZ removal, respectively. The low iron and citrate doses and the fast radical generation at neutral pH make the Fe(II)/citrate/UV/PMS process suitable for degrading recalcitrant organic compounds in potable water. Copyright © 2017 Elsevier Ltd. All rights reserved.

Study of the Gray Scale, Polychromatic, Distortion Invariant Neural Networks Using the Ipa Model.

Science.gov (United States)

Uang, Chii-Maw

Research in the optical neural network field is primarily motivated by the fact that humans recognize objects better than the conventional digital computers and the massively parallel inherent nature of optics. This research represents a continuous effort during the past several years in the exploitation of using neurocomputing for pattern recognition. Based on the interpattern association (IPA) model and Hamming net model, many new systems and applications are introduced. A gray level discrete associative memory that is based on object decomposition/composition is proposed for recognizing gray-level patterns. This technique extends the processing ability from the binary mode to gray-level mode, and thus the information capacity is increased. Two polychromatic optical neural networks using color liquid crystal television (LCTV) panels for color pattern recognition are introduced. By introducing a color encoding technique in conjunction with the interpattern associative algorithm, a color associative memory was realized. Based on the color decomposition and composition technique, a color exemplar-based Hamming net was built for color image classification. A shift-invariant neural network is presented through use of the translation invariant property of the modulus of the Fourier transformation and the hetero-associative interpattern association (IPA) memory. To extract the main features, a quadrantal sampling method is used to sampled data and then replace the training patterns. Using the concept of hetero-associative memory to recall the distorted object. A shift and rotation invariant neural network using an interpattern hetero-association (IHA) model is presented. To preserve the shift and rotation invariant properties, a set of binarized-encoded circular harmonic expansion (CHE) functions at the Fourier domain is used as the training set. We use the shift and symmetric properties of the modulus of the Fourier spectrum to avoid the problem of centering the CHE

Adsorption of tetracycline on soil and sediment: Effects of pH and the presence of Cu(II)

International Nuclear Information System (INIS)

Zhang Zheyun; Sun Ke; Gao Bo; Zhang Guixiang; Liu Xitao; Zhao Ye

2011-01-01

Tetracycline (TC) is frequently detected in the environment, however, knowledge on the environmental fate and transport of TC is still limited. Batch adsorption experiments of TC by soil and sediment samples were conducted. The distribution of charge and electrostatic potential of individual atoms of various TC species in the aqueous solution were determined using MOPAC version 0.034 W program in ChemBio3D Ultra software. Most of the adsorption isotherms on the soil, river and marine sediments were well fitted with the Freundlich and Polanyi-Manes (PMM) models. The single point organic carbon (OC)-normalized adsorption distribution coefficients (K OC ) and PMM saturated adsorption capacity (Q OC 0 ) values of TC were associated with the mesopore volume and clay content to a greater extent, indicating the mesopore volume of the soil and sediments and their clay content possibly influenced the fate and transport of TC in the natural environment. The adsorption of TC on soil and sediments strongly depended on the pH and presence of Cu(II). The presence of Cu(II) facilitated TC adsorption on soil and sediments at low pH (pH < 5), possibly due to the metallic complexation and surface-bridging mechanism by Cu(II) adsorption on soil and sediments. The cation exchange interaction, metallic complexation and Coulombic interaction of mechanisms for adsorption of TC to soils and sediments were further supported by quantum chemical calculation of various TC species in different pH.

Cubic systems with invariant affine straight lines of total parallel multiplicity seven

Directory of Open Access Journals (Sweden)

Alexandru Suba

2013-12-01

Full Text Available In this article, we study the planar cubic differential systems with invariant affine straight lines of total parallel multiplicity seven. We classify these system according to their geometric properties encoded in the configurations of invariant straight lines. We show that there are only 17 different topological phase portraits in the Poincar\\'e disc associated to this family of cubic systems up to a reversal of the sense of their orbits, and we provide representatives of every class modulo an affine change of variables and rescaling of the time variable.

Testing Lorentz invariance of dark matter

CERN Document Server

Blas, Diego; Sibiryakov, Sergey

2012-01-01

We study the possibility to constrain deviations from Lorentz invariance in dark matter (DM) with cosmological observations. Breaking of Lorentz invariance generically introduces new light gravitational degrees of freedom, which we represent through a dynamical timelike vector field. If DM does not obey Lorentz invariance, it couples to this vector field. We find that this coupling affects the inertial mass of small DM halos which no longer satisfy the equivalence principle. For large enough lumps of DM we identify a (chameleon) mechanism that restores the inertial mass to its standard value. As a consequence, the dynamics of gravitational clustering are modified. Two prominent effects are a scale dependent enhancement in the growth of large scale structure and a scale dependent bias between DM and baryon density perturbations. The comparison with the measured linear matter power spectrum in principle allows to bound the departure from Lorentz invariance of DM at the per cent level.

Testing Lorentz invariance of dark matter

Energy Technology Data Exchange (ETDEWEB)

Blas, Diego [Theory Group, Physics Department, CERN, CH-1211 Geneva 23 (Switzerland); Ivanov, Mikhail M.; Sibiryakov, Sergey, E-mail: diego.blas@cern.ch, E-mail: mm.ivanov@physics.msu.ru, E-mail: sibir@inr.ac.ru [Faculty of Physics, Moscow State University, Vorobjevy Gory, 119991 Moscow (Russian Federation)

2012-10-01

We study the possibility to constrain deviations from Lorentz invariance in dark matter (DM) with cosmological observations. Breaking of Lorentz invariance generically introduces new light gravitational degrees of freedom, which we represent through a dynamical timelike vector field. If DM does not obey Lorentz invariance, it couples to this vector field. We find that this coupling affects the inertial mass of small DM halos which no longer satisfy the equivalence principle. For large enough lumps of DM we identify a (chameleon) mechanism that restores the inertial mass to its standard value. As a consequence, the dynamics of gravitational clustering are modified. Two prominent effects are a scale dependent enhancement in the growth of large scale structure and a scale dependent bias between DM and baryon density perturbations. The comparison with the measured linear matter power spectrum in principle allows to bound the departure from Lorentz invariance of DM at the per cent level.

Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors.

Science.gov (United States)

Pineda, M; González-Acosta, M; Thompson, B A; Sánchez, R; Gómez, C; Martínez-López, J; Perea, J; Caldés, T; Rodríguez, Y; Landolfi, S; Balmaña, J; Lázaro, C; Robles, L; Capellá, G; Rueda, D

2015-06-01

Lynch syndrome (LS) is an autosomal dominant cancer-susceptibility disease caused by inactivating germline mutations in mismatch repair (MMR) genes. Variants of unknown significance (VUS) are often detected in mutational analysis of MMR genes. Here we describe a large family fulfilling Amsterdam I criteria carrying two rare VUS in the MLH1 gene: c.121G > C (p.D41H) and c.2128A > G (p.N710D). Collection of clinico-pathological data, multifactorial analysis, in silico predictions, and functional analyses were used to elucidate the clinical significance of the identified MLH1 VUS. Only the c.121G > C variant cosegregated with LS-associated tumors in the family. Diagnosed colorectal tumors were microsatellite unstable although immunohistochemical staining revealed no loss of MMR proteins expression. Multifactorial likelihood analysis classified c.2128A > G as a non-pathogenic variant and c.121G > C as pathogenic. In vitro functional tests revealed impaired MMR activity and diminished expression of c.121G > C. Accordingly, the N710 residue is located in the unconserved MLH1 C-terminal domain, whereas D41 is highly conserved and located in the ATPase domain. The obtained results will enable adequate genetic counseling of c.121G > C and c.2128A > G variant carriers and their families. Furthermore, they exemplify how cumulative data and comprehensive analyses are mandatory to refine the classification of MMR variants. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The Schroeder functional equation and its relation to the invariant measures of chaotic maps

International Nuclear Information System (INIS)

Luevano, Jose-Ruben; Pina, Eduardo

2008-01-01

The aim of this paper is to show that the invariant measure for a class of one-dimensional chaotic maps, T(x), is an extended solution of the Schroeder functional equation, q(T(x)) = λq(x), induced by them. Hence, we give a unified treatment of a collection of exactly solved examples worked out in the current literature. In particular, we show that these examples belong to a class of functions introduced by Mira (see the text). Moreover, as a new example, we compute the invariant densities for a class of rational maps having the Weierstrass p function as an invariant one. Also, we study the relation between that equation and the well-known Frobenius-Perron and Koopman's operators

Longitudinal multigroup invariance analysis of the satisfaction with food-related life scale in university students.

Science.gov (United States)

Schnettler, Berta; Miranda, Horacio; Miranda-Zapata, Edgardo; Salinas-Oñate, Natalia; Grunert, Klaus G; Lobos, Germán; Sepúlveda, José; Orellana, Ligia; Hueche, Clementina; Bonilla, Héctor

2017-06-01

This study examined longitudinal measurement invariance in the Satisfaction with Food-related Life (SWFL) scale using follow-up data from university students. We examined this measure of the SWFL in different groups of students, separated by various characteristics. Through non-probabilistic longitudinal sampling, 114 university students (65.8% female, mean age: 22.5) completed the SWFL questionnaire three times, over intervals of approximately one year. Confirmatory factor analysis was used to examine longitudinal measurement invariance. Two types of analysis were conducted: first, a longitudinal invariance by time, and second, a multigroup longitudinal invariance by sex, age, socio-economic status and place of residence during the study period. Results showed that the 3-item version of the SWFL exhibited strong longitudinal invariance (equal factor loadings and equal indicator intercepts). Longitudinal multigroup invariance analysis also showed that the 3-item version of the SWFL displays strong invariance by socio-economic status and place of residence during the study period over time. Nevertheless, it was only possible to demonstrate equivalence of the longitudinal factor structure among students of both sexes, and among those older and younger than 22 years. Generally, these findings suggest that the SWFL scale has satisfactory psychometric properties for longitudinal measurement invariance in university students with similar characteristics as the students that participated in this research. It is also possible to suggest that satisfaction with food-related life is associated with sex and age. Copyright © 2017 Elsevier Ltd. All rights reserved.

On stabilisability of 2-D MIMO shift-invariant systems

Czech Academy of Sciences Publication Activity Database

Augusta, Petr; Augustová, Petra

2013-01-01

Roč. 350, č. 10 (2013), s. 2949-2966 ISSN 0016-0032 R&D Projects: GA ČR GPP103/12/P494 Institutional support: RVO:67985556 Keywords : spatially invariant system * stabilisation * multiple-input-multiple-output system, * positive polynomial Subject RIV: BC - Control Systems Theory Impact factor: 2.260, year: 2013 http://library.utia.cas.cz/separaty/2013/TR/augusta-0398772.pdf

Differential invariants of generic parabolic Monge–Ampère equations

International Nuclear Information System (INIS)

Ferraioli, D Catalano; Vinogradov, A M

2012-01-01

Some new results on the geometry of classical parabolic Monge–Ampère equations (PMAs) are presented. PMAs are either integrable, or non-integrable according to the integrability of its characteristic distribution. All integrable PMAs are locally equivalent to the equation u xx = 0. We study non-integrable PMAs by associating with each of them a one-dimensional distribution on the corresponding first-order jet manifold, called the directing distribution. According to some property of this distribution, non-integrable PMAs are subdivided into three classes, one generic and two special. Generic PMAs are completely characterized by their directing distributions, and we study canonical models of the latter, projective curve bundles (PCB). A PCB is a one-dimensional sub-bundle of the projectivized cotangent bundle of a four-dimensional manifold. Differential invariants of projective curves composing such a bundle are used to construct a series of contact differential invariants for corresponding PMAs. These give a solution of the equivalence problem for generic PMAs with respect to contact transformations. The introduced invariants measure the nonlinearity of PMAs in an exact manner. (paper)

The long-term functional outcome of type II odontoid fractures managed non-operatively.

LENUS (Irish Health Repository)

Butler, J S

2010-10-01

Odontoid fractures currently account for 9-15% of all adult cervical spine fractures, with type II fractures accounting for the majority of these injuries. Despite recent advances in internal fixation techniques, the management of type II fractures still remains controversial with advocates still supporting non-rigid immobilization as the definitive treatment of these injuries. At the NSIU, over an 11-year period between 1 July 1996 and 30 June 2006, 66 patients (n = 66) were treated by external immobilization for type II odontoid fractures. The medical records, radiographs and CT scans of all patients identified were reviewed. Clinical follow-up evaluation was performed using the Cervical Spine Outcomes Questionnaire (CSOQ). The objectives of this study were to evaluate the long-term functional outcome of patients suffering isolated type II odontoid fractures managed non-operatively and to correlate patient age and device type with clinical and functional outcome. Of the 66 patients, there were 42 males and 24 females (M:F = 1.75:1) managed non-operatively for type II odontoid fractures. The mean follow-up time was 66 months. Advancing age was highly correlated with poorer long-term functional outcomes when assessing neck pain (r = 0.19, P = 0.1219), shoulder and arm pain (r = 0.41, P = 0.0007), physical symptoms (r = 0.25, P = 0.472), functional disability (r = 0.24, P = 0.0476) and psychological distress (r = 0.41, P = 0.0007). Patients >65 years displayed a higher rate of pseudoarthrosis (21.43 vs. 1.92%) and established non-union (7.14 vs. 0%) than patients <65 years. The non-operative management of type II odontoid fractures is an effective and satisfactory method of treating type II odontoid fractures, particularly those of a stable nature. However, patients of advancing age have been demonstrated to have significantly poorer functional outcomes in the long term. This may be linked to higher rates of non-union.

arXiv Evidence for the rare decay $\\Sigma^+ \\to p \\mu^+ \\mu^-$

CERN Document Server

Aaij, Roel; LHCb Collaboration; Adinolfi, Marco; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Alfonso Albero, Alejandro; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Andreassi, Guido; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Archilli, Flavio; d'Argent, Philippe; Arnau Romeu, Joan; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Atzeni, Michele; Auriemma, Giulio; Baalouch, Marouen; Babuschkin, Igor; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baker, Sophie; Balagura, Vladislav; Baldini, Wander; Baranov, Alexander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Baryshnikov, Fedor; Batozskaya, Varvara; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Beiter, Andrew; Bel, Lennaert; Beliy, Nikita; Bellee, Violaine; Belloli, Nicoletta; Belous, Konstantin; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Beranek, Sarah; Berezhnoy, Alexander; Bernet, Roland; Berninghoff, Daniel; Bertholet, Emilie; Bertolin, Alessandro; Betancourt, Christopher; Betti, Federico; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bezshyiko, Iaroslava; Bifani, Simone; Billoir, Pierre; Birnkraut, Alex; Bizzeti, Andrea; Bjørn, Mikkel; Blake, Thomas; Blanc, Frederic; Blusk, Steven; Bocci, Valerio; Boettcher, Thomas; Bondar, Alexander; Bondar, Nikolay; Bordyuzhin, Igor; Borghi, Silvia; Borisyak, Maxim; Borsato, Martino; Bossu, Francesco; Boubdir, Meriem; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Braun, Svende; Brodzicka, Jolanta; Brundu, Davide; Buchanan, Emma; Burr, Christopher; Bursche, Albert; Buytaert, Jan; Byczynski, Wiktor; Cadeddu, Sandro; Cai, Hao; Calabrese, Roberto; Calladine, Ryan; Calvi, Marta; Calvo Gomez, Miriam; Camboni, Alessandro; Campana, Pierluigi; Campora Perez, Daniel Hugo; Capriotti, Lorenzo; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carniti, Paolo; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Cattaneo, Marco; Cavallero, Giovanni; Cenci, Riccardo; Chamont, David; Chapman, Matthew George; Charles, Matthew; Charpentier, Philippe; Chatzikonstantinidis, Georgios; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu Faye; Chitic, Stefan-Gabriel; Chobanova, Veronika; Chrzaszcz, Marcin; Chubykin, Alexsei; Ciambrone, Paolo; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cogoni, Violetta; Cojocariu, Lucian; Collins, Paula; Colombo, Tommaso; Comerma-Montells, Albert; Contu, Andrea; Coombs, George; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Costa Sobral, Cayo Mar; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Crocombe, Andrew; Cruz Torres, Melissa Maria; Currie, Robert; D'Ambrosio, Carmelo; Da Cunha Marinho, Franciole; Da Silva, Cesar Luiz; Dall'Occo, Elena; Dalseno, Jeremy; Davis, Adam; De Aguiar Francisco, Oscar; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Serio, Marilisa; De Simone, Patrizia; Dean, Cameron Thomas; Decamp, Daniel; Del Buono, Luigi; Dembinski, Hans Peter; Demmer, Moritz; Dendek, Adam; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Dey, Biplab; Di Canto, Angelo; Di Nezza, Pasquale; Dijkstra, Hans; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Douglas, Lauren; Dovbnya, Anatoliy; Dreimanis, Karlis; Dufour, Laurent; Dujany, Giulio; Durante, Paolo; Durham, John Matthew; Dutta, Deepanwita; Dzhelyadin, Rustem; Dziewiecki, Michal; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Farley, Nathanael; Farry, Stephen; Fazzini, Davide; Federici, Luca; Ferguson, Dianne; Fernandez, Gerard; Fernandez Declara, Placido; Fernandez Prieto, Antonio; Ferrari, Fabio; Ferreira Lopes, Lino; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fini, Rosa Anna; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fleuret, Frederic; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Franco Lima, Vinicius; Frank, Markus; Frei, Christoph; Fu, Jinlin; Funk, Wolfgang; Furfaro, Emiliano; Färber, Christian; Gabriel, Emmy; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; Garcia Martin, Luis Miguel; García Pardiñas, Julián; Garra Tico, Jordi; Garrido, Lluis; Gascon, David; Gaspar, Clara; Gavardi, Laura; Gazzoni, Giulio; Gerick, David; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianì, Sebastiana; Gibson, Valerie; Girard, Olivier Göran; Giubega, Lavinia-Helena; Gizdov, Konstantin; Gligorov, Vladimir; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gorelov, Igor Vladimirovich; Gotti, Claudio; Govorkova, Ekaterina; Grabowski, Jascha Peter; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graverini, Elena; Graziani, Giacomo; Grecu, Alexandru; Greim, Roman; Griffith, Peter; Grillo, Lucia; Gruber, Lukas; Gruberg Cazon, Barak Raimond; Grünberg, Oliver; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Göbel, Carla; Hadavizadeh, Thomas; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hamilton, Brian; Han, Xiaoxue; Hancock, Thomas Henry; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Hasse, Christoph; Hatch, Mark; He, Jibo; Hecker, Malte; Heinicke, Kevin; Heister, Arno; Hennessy, Karol; Henrard, Pierre; Henry, Louis; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hopchev, Plamen Hristov; Hu, Wenhua; Huang, Wenqian; Huard, Zachary; Hulsbergen, Wouter; Humair, Thibaud; Hushchyn, Mikhail; Hutchcroft, David; Ibis, Philipp; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jalocha, Pawel; Jans, Eddy; Jawahery, Abolhassan; Jiang, Feng; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kandybei, Sergii; Karacson, Matthias; Kariuki, James Mwangi; Karodia, Sarah; Kazeev, Nikita; Kecke, Matthieu; Keizer, Floris; Kelsey, Matthew; Kenzie, Matthew; Ketel, Tjeerd; Khairullin, Egor; Khanji, Basem; Khurewathanakul, Chitsanu; Kim, Kyung Eun; Kirn, Thomas; Klaver, Suzanne; Klimaszewski, Konrad; Klimkovich, Tatsiana; Koliiev, Serhii; Kolpin, Michael; Kopecna, Renata; Koppenburg, Patrick; Kosmyntseva, Alena; Kotriakhova, Sofia; Kozeiha, Mohamad; Kravchuk, Leonid; Kreps, Michal; Kress, Felix Johannes; Krokovny, Pavel; Krzemien, Wojciech; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kuonen, Axel Kevin; Kvaratskheliya, Tengiz; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lanfranchi, Gaia; Langenbruch, Christoph; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; Leflat, Alexander; Lefrançois, Jacques; Lefèvre, Regis; Lemaitre, Florian; Lemos Cid, Edgar; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Pei-Rong; Li, Tenglin; Li, Yiming; Li, Zhuoming; Liang, Xixin; Likhomanenko, Tatiana; Lindner, Rolf; Lionetto, Federica; Lisovskyi, Vitalii; Liu, Xuesong; Loh, David; Loi, Angelo; Longstaff, Iain; Lopes, Jose; Lucchesi, Donatella; Lucio Martinez, Miriam; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Lusiani, Alberto; Lyu, Xiao-Rui; Machefert, Frederic; Maciuc, Florin; Macko, Vladimir; Mackowiak, Patrick; Maddrell-Mander, Samuel; Maev, Oleg; Maguire, Kevin; Maisuzenko, Dmitrii; Majewski, Maciej Witold; Malde, Sneha; Malecki, Bartosz; Malinin, Alexander; Maltsev, Timofei; Manca, Giulia; Mancinelli, Giampiero; Marangotto, Daniele; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marinangeli, Matthieu; Marino, Pietro; Marks, Jörg; Martellotti, Giuseppe; Martin, Morgan; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Massafferri, André; Matev, Rosen; Mathad, Abhijit; Mathe, Zoltan; Matteuzzi, Clara; Mauri, Andrea; Maurice, Emilie; Maurin, Brice; Mazurov, Alexander; McCann, Michael; McNab, Andrew; McNulty, Ronan; Mead, James Vincent; Meadows, Brian; Meaux, Cedric; Meier, Frank; Meinert, Nis; Melnychuk, Dmytro; Merk, Marcel; Merli, Andrea; Michielin, Emanuele; Milanes, Diego Alejandro; Millard, Edward James; Minard, Marie-Noelle; Minzoni, Luca; Mitzel, Dominik Stefan; Mogini, Andrea; Molina Rodriguez, Josue; Mombächer, Titus; Monroy, Igancio Alberto; Monteil, Stephane; Morandin, Mauro; Morello, Michael Joseph; Morgunova, Olga; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Mulder, Mick; Müller, Dominik; Müller, Janine; Müller, Katharina; Müller, Vanessa; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nandi, Anita; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Thi Dung; Nguyen-Mau, Chung; Nieswand, Simon; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Nogay, Alla; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Ogilvy, Stephen; Oldeman, Rudolf; Onderwater, Gerco; Ossowska, Anna; Otalora Goicochea, Juan Martin; Owen, Patrick; Oyanguren, Maria Aranzazu; Pais, Preema Rennee; Palano, Antimo; Palutan, Matteo; Panshin, Gennady; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Parker, William; Parkes, Christopher; Passaleva, Giovanni; Pastore, Alessandra; Patel, Mitesh; Patrignani, Claudia; Pearce, Alex; Pellegrino, Antonio; Penso, Gianni; Pepe Altarelli, Monica; Perazzini, Stefano; Pereima, Dmitrii; Perret, Pascal; Pescatore, Luca; Petridis, Konstantinos; Petrolini, Alessandro; Petrov, Aleksandr; Petruzzo, Marco; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pietrzyk, Guillaume; Pikies, Malgorzata; Pinci, Davide; Pisani, Flavio; Pistone, Alessandro; Piucci, Alessio; Placinta, Vlad-Mihai; Playfer, Stephen; Plo Casasus, Maximo; Polci, Francesco; Poli Lener, Marco; Poluektov, Anton; Polyakov, Ivan; Polycarpo, Erica; Pomery, Gabriela Johanna; Ponce, Sebastien; Popov, Alexander; Popov, Dmitry; Poslavskii, Stanislav; Potterat, Cédric; Price, Eugenia; Prisciandaro, Jessica; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Pullen, Hannah Louise; Punzi, Giovanni; Qian, Wenbin; Qin, Jia-Jia; Quagliani, Renato; Quintana, Boris; Rachwal, Bartlomiej; Rademacker, Jonas; Rama, Matteo; Ramos Pernas, Miguel; Rangel, Murilo; Raniuk, Iurii; Ratnikov, Fedor; Raven, Gerhard; Ravonel Salzgeber, Melody; Reboud, Meril; Redi, Federico; Reichert, Stefanie; dos Reis, Alberto; Remon Alepuz, Clara; Renaudin, Victor; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Robbe, Patrick; Robert, Arnaud; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Lopez, Jairo Alexis; Rogozhnikov, Alexey; Roiser, Stefan; Rollings, Alexandra Paige; Romanovskiy, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rudolph, Matthew Scott; Ruf, Thomas; Ruiz Valls, Pablo; Ruiz Vidal, Joan; Saborido Silva, Juan Jose; Sadykhov, Elnur; Sagidova, Naylya; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santimaria, Marco; Santovetti, Emanuele; Sarpis, Gediminas; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrina, Darya; Schael, Stefan; Schellenberg, Margarete; Schiller, Manuel; Schindler, Heinrich; Schmelling, Michael; Schmelzer, Timon; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schreiner, HF; Schubiger, Maxime; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Semennikov, Alexander; Sepulveda, Eduardo Enrique; Sergi, Antonino; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Siddi, Benedetto Gianluca; Silva Coutinho, Rafael; Silva de Oliveira, Luiz Gustavo; Simi, Gabriele; Simone, Saverio; Sirendi, Marek; Skidmore, Nicola; Skwarnicki, Tomasz; Smith, Iwan Thomas; Smith, Jackson; Smith, Mark; Soares Lavra, Lais; Sokoloff, Michael; Soler, Paul; Souza De Paula, Bruno; Spaan, Bernhard; Spradlin, Patrick; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Stefko, Pavol; Stefkova, Slavomira; Steinkamp, Olaf; Stemmle, Simon; Stenyakin, Oleg; Stepanova, Margarita; Stevens, Holger; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Stramaglia, Maria Elena; Straticiuc, Mihai; Straumann, Ulrich; Strokov, Sergey; Sun, Jiayin; Sun, Liang; Swientek, Krzysztof; Syropoulos, Vasileios; Szumlak, Tomasz; Szymanski, Maciej Pawel; T'Jampens, Stephane; Tayduganov, Andrey; Tekampe, Tobias; Tellarini, Giulia; Teubert, Frederic; Thomas, Eric; van Tilburg, Jeroen; Tilley, Matthew James; Tisserand, Vincent; Tobin, Mark; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Tourinho Jadallah Aoude, Rafael; Tournefier, Edwige; Traill, Murdo; Tran, Minh Tâm; Tresch, Marco; Trisovic, Ana; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tully, Alison; Tuning, Niels; Ukleja, Artur; Usachov, Andrii; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagner, Alexander; Vagnoni, Vincenzo; Valassi, Andrea; Valat, Sebastien; Valenti, Giovanni; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vecchi, Stefania; van Veghel, Maarten; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Venkateswaran, Aravindhan; Verlage, Tobias Anton; Vernet, Maxime; Vesterinen, Mika; Viana Barbosa, Joao Vitor; Vieira, Daniel; Vieites Diaz, Maria; Viemann, Harald; Vilasis-Cardona, Xavier; Vitti, Marcela; Volkov, Vladimir; Vollhardt, Achim; Voneki, Balazs; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; de Vries, Jacco; Vázquez Sierra, Carlos; Waldi, Roland; Walsh, John; Wang, Jianchun; Wang, Yilong; Ward, David; Wark, Heather Mckenzie; Watson, Nigel; Websdale, David; Weiden, Andreas; Weisser, Constantin; Whitehead, Mark; Wicht, Jean; Wilkinson, Guy; Wilkinson, Michael; Williams, Mark Richard James; Williams, Mike; Williams, Timothy; Wilson, Fergus; Wimberley, Jack; Winn, Michael Andreas; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wyllie, Kenneth; Xie, Yuehong; Xu, Menglin; Xu, Qingnian; Xu, Zehua; Xu, Zhirui; Yang, Zhenwei; Yang, Zishuo; Yao, Yuezhe; Yin, Hang; Yu, Jiesheng; Yuan, Xuhao; Yushchenko, Oleg; Zarebski, Kristian Alexander; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Yanxi; Zhelezov, Alexey; Zheng, Yangheng; Zhu, Xianglei; Zhukov, Valery; Zonneveld, Jennifer Brigitta; Zucchelli, Stefano

2018-06-01

A search for the rare decay $\\Sigma^+ \\to p \\mu^+ \\mu^-$ is performed using $pp$ collision data recorded by the LHCb experiment at centre-of-mass energies $\\sqrt{s} = 7$ and $8$ TeV, corresponding to an integrated luminosity of $3 fb^{-1}$. An excess of events is observed with respect to the background expectation, with a signal significance of 4.1 standard deviations. No significant structure is observed in the dimuon invariant mass distribution, in contrast with a previous result from the HyperCP experiment. The measured $\\Sigma^+ \\to p \\mu^+ \\mu^-$ branching fraction is $(2.2\\,^{+\\,1.8}_{-\\,1.3})\\times 10^{-8}$, where statistical and systematic uncertainties are included, which is consistent with the Standard Model prediction.

Solar photocatalytic removal of Cu(II), Ni(II), Zn(II) and Pb(II): Speciation modeling of metal-citric acid complexes

International Nuclear Information System (INIS)

Kabra, Kavita; Chaudhary, Rubina; Sawhney, R.L.

2008-01-01

The present study is targeted on solar photocatalytic removal of metal ions from wastewater. Photoreductive deposition and dark adsorption of metal ions Cu(II), Ni(II), Pb(II) and Zn(II), using solar energy irradiated TiO 2 , has been investigated. Citric acid has been used as a hole scavenger. Modeling of metal species has been performed and speciation is used as a tool for discussing the photodeposition trends. Ninety-seven percent reductive deposition was obtained for copper. The deposition values of other metals were significantly low [nickel (36.4%), zinc (22.2%) and lead (41.4%)], indicating that the photocatalytic treatment process, using solar energy, was more suitable for wastewater containing Cu(II) ions. In absence of citric acid, the decreasing order deposition was Cu(II) > Ni(II) > Pb(II) > Zn(II), which proves the theoretical thermodynamic predictions about the metals

Conformal invariance in supergravity

International Nuclear Information System (INIS)

Bergshoeff, E.A.

1983-01-01

In this thesis the author explains the role of conformal invariance in supergravity. He presents the complete structure of extended conformal supergravity for N <= 4. The outline of this work is as follows. In chapter 2 he briefly summarizes the essential properties of supersymmetry and supergravity and indicates the use of conformal invariance in supergravity. The idea that the introduction of additional symmetry transformations can make clear the structure of a field theory is not reserved to supergravity only. By means of some simple examples it is shown in chapter 3 how one can always introduce additional gauge transformations in a theory of massive vector fields. Moreover it is shown how the gauge invariant formulation sometimes explains the quantum mechanical properties of the theory. In chapter 4 the author defines the conformal transformations and summarizes their main properties. He explains how these conformal transformations can be used to analyse the structure of gravity. The supersymmetric extension of these results is discussed in chapter 5. Here he describes as an example how N=1 supergravity can be reformulated in a conformally-invariant way. He also shows that beyond N=1 the gauge fields of the superconformal symmetries do not constitute an off-shell field representation of extended conformal supergravity. Therefore, in chapter 6, a systematic method to construct the off-shell formulation of all extended conformal supergravity theories with N <= 4 is developed. As an example he uses this method to construct N=1 conformal supergravity. Finally, in chapter 7 N=4 conformal supergravity is discussed. (Auth.)

Knot invariants and M-theory: Proofs and derivations

Science.gov (United States)

Errasti Díez, Verónica

2018-01-01

We construct two distinct yet related M-theory models that provide suitable frameworks for the study of knot invariants. We then focus on the four-dimensional gauge theory that follows from appropriately compactifying one of these M-theory models. We show that this theory has indeed all required properties to host knots. Our analysis provides a unifying picture of the various recent works that attempt an understanding of knot invariants using techniques of four-dimensional physics. This is a companion paper to K. Dasgupta, V. Errasti Díez, P. Ramadevi, and R. Tatar, Phys. Rev. D 95, 026010 (2017), 10.1103/PhysRevD.95.026010, covering all but Sec. III C. It presents a detailed mathematical derivation of the main results there, as well as additional material. Among the new insights, those related to supersymmetry and the topological twist are highlighted. This paper offers an alternative, complementary formulation of the contents in the first paper, but is self-contained and can be read independently.

Invariant Solutions for a Class of Perturbed Nonlinear Wave Equations

Directory of Open Access Journals (Sweden)

Waheed A. Ahmed

2017-11-01

Full Text Available Approximate symmetries of a class of perturbed nonlinear wave equations are computed using two newly-developed methods. Invariant solutions associated with the approximate symmetries are constructed for both methods. Symmetries and solutions are compared through discussing the advantages and disadvantages of each method.

Lorentz violating p-form gauge theories in superspace

Energy Technology Data Exchange (ETDEWEB)

Upadhyay, Sudhaker [Indian Institute of Technology Kharagpur, Centre for Theoretical Studies, Kharagpur (India); Shah, Mushtaq B.; Ganai, Prince A. [National Institute of Technology, Department of Physics, Srinagar, Kashmir (India)

2017-03-15

Very special relativity (VSR) keeps the main features of special relativity but breaks rotational invariance due to an intrinsic preferred direction. We study the VSR-modified extended BRST and anti-BRST symmetry of the Batalin-Vilkovisky (BV) actions corresponding to the p = 1, 2, 3-form gauge theories. Within the VSR framework, we discuss the extended BRST invariant and extended BRST and anti-BRST invariant superspace formulations for these BV actions. Here we observe that the VSR-modified extended BRST invariant BV actions corresponding to the p = 1, 2, 3-form gauge theories can be written in a manifestly covariant manner in a superspace with one Grassmann coordinate. Moreover, two Grassmann coordinates are required to describe the VSR-modified extended BRST and extended anti-BRST invariant BV actions in a superspace. These results are consistent with the Lorentz-invariant (special relativity) formulation. (orig.)

Object recognition by implicit invariants

Czech Academy of Sciences Publication Activity Database

Flusser, Jan; Kautsky, J.; Šroubek, Filip

2007-01-01

Roč. 2007, č. 4673 (2007), s. 856-863 ISSN 0302-9743. [Computer Analysis of Images and Patterns. Vienna, 27.08.2007-29.08.2007] R&D Projects: GA MŠk 1M0572 Institutional research plan: CEZ:AV0Z10750506 Keywords : Invariants * implicit invariants * moments * orthogonal polynomials * nonlinear object deformation Subject RIV: JD - Computer Applications, Robotics Impact factor: 0.402, year: 2005 http:// staff .utia.cas.cz/sroubekf/papers/CAIP_07.pdf

BanII dimorphic site located in the third intron of the human apolipoprotein AI (APOA1) gene

Energy Technology Data Exchange (ETDEWEB)

Coleman, R T; Kresnak, M T; Frossard, P M

1988-02-11

A 0.7kb fragment generated by AvaII digestion of pBL13AI, a 0.965kb full-length human apolipoprotein AI cDNA was cloned into the EcoRI site of pBR322. The apoAI cDNA was isolated from a lambdagt10 human fetal liver cDNA library. BanII (GPuGCPyC) (International Biotechnologies, Inc.) identifies two invariant bands at 1122bp and 417bp, and a single two-allele polymorphism with bands at either 274bp or 452bp. The human apolipoprotein AI-CIII-AIV gene complex has been localized on the long arm of chromosome 11 by Southern blot analysis of human-chinese hamster cell hybrids. Co-dominant segregation has been observed in two families (13 individuals). The BanII restriction map was constructed from DNA sequence data of the human apoAI gene. The 452bp fragment is generated by the loss of a BanII dimorphic site in the third intron of the apoAI gene, between the 178bp and the 274bp fragments.

Modular invariance, chiral anomalies and contact terms

International Nuclear Information System (INIS)

Kutasov, D.

1988-03-01

The chiral anomaly in heterotic strings with full and partial modular invariance in D=2n+2 dimensions is calculated. The boundary terms which were present in previous calculations are shown to be cancelled in the modular invariant case by contact terms, which can be obtained by an appropriate analytic continuation. The relation to the low energy field theory is explained. In theories with partial modular invariance, an expression for the anomaly is obtained and shown to be non zero in general. (author)

Analyzing vortex breakdown flow structures by assignment of colors to tensor invariants.

Science.gov (United States)

Rütten, Markus; Chong, Min S

2006-01-01

Topological methods are often used to describe flow structures in fluid dynamics and topological flow field analysis usually relies on the invariants of the associated tensor fields. A visual impression of the local properties of tensor fields is often complex and the search of a suitable technique for achieving this is an ongoing topic in visualization. This paper introduces and assesses a method of representing the topological properties of tensor fields and their respective flow patterns with the use of colors. First, a tensor norm is introduced, which preserves the properties of the tensor and assigns the tensor invariants to values of the RGB color space. Secondly, the RGB colors of the tensor invariants are transferred to corresponding hue values as an alternative color representation. The vectorial tensor invariants field is reduced to a scalar hue field and visualization of iso-surfaces of this hue value field allows us to identify locations with equivalent flow topology. Additionally highlighting by the maximum of the eigenvalue difference field reflects the magnitude of the structural change of the flow. The method is applied on a vortex breakdown flow structure inside a cylinder with a rotating lid.

Effect of the tether on the Mg(II), Ca(II), Cu(II) and Fe(III) stability constants and pM values of chelating agents related to EDDHA.

Science.gov (United States)

Sierra, Miguel A; Gómez-Gallego, Mar; Alcázar, Roberto; Lucena, Juan J; Yunta, Felipe; García-Marco, Sonia

2004-11-07

The effect of the length and the structure of the tether on the chelating ability of EDDHA-like chelates have not been established. In this work, PDDHA (propylenediamine-N,N'-bis(o-hydroxyphenyl)acetic acid), BDDHA (butylenediamine-N,N'-bis(o-hydroxyphenyl)acetic acid) and XDDHA (p-xylylenediamine-N,N'-bis(o-hydroxyphenyl)acetic acid) have been obtained and their chemical behaviour has been studied and compared with that of EDDHA following our methodology. The purity of the chelating agents, and their protonation, Ca(II), Mg(II), Fe(III) and Cu(II) stability constants and pM values have been determined. The stability constants and pM values indicate that EDDHA forms the most stable chelates followed by PDDHA. However, the differences among the pFe values are small when a nutrient solution is used, and in these conditions the XDDHA/Fe(III) chelate is the most stable. The results obtained in this work indicate that all the chelating agents studied can be used as iron chlorosis correctors and they can be applied to soil/plant systems.

Strong coupling in a gauge invariant field theory

Energy Technology Data Exchange (ETDEWEB)

Johnson, K. [Physics Department, Massachusetts Institute of Technology, Cambridge, MA (United States)

1963-01-15

I would like to discuss some approximations which may be significant in the domain of strong coupling in a field system analogous to quantum electrodynamics. The motivation of this work is the idea that the strong couplings and elementary particle spectrum may be the consequence of the dynamics of a system whose underlying description is in terms of a set of Fermi fields gauge invariantly coupled to a single (''bare'') massless neutral vector field. The basis of this gauge invariance would of course be the exact conservation law of baryons or ''nucleonic charge''. It seems to me that a coupling scheme based on an invariance principle is most attractive if that invariance is an exact one. It would then be nice to try to account for the approximate invariance principles in the same way one would describe ''accidental degeneracies'' in any quantum system.

Quantum Hall Conductivity and Topological Invariants

Science.gov (United States)

Reyes, Andres

2001-04-01

A short survey of the theory of the Quantum Hall effect is given emphasizing topological aspects of the quantization of the conductivity and showing how topological invariants can be derived from the hamiltonian. We express these invariants in terms of Chern numbers and show in precise mathematical terms how this relates to the Kubo formula.

Post-transplant HLA class II antibodies and high soluble CD30 levels are independently associated with poor kidney graft survival.

Science.gov (United States)

Langan, L L; Park, L P; Hughes, T L; Irish, A; Luxton, G; Witt, C S; Christiansen, F T

2007-04-01

HLA-specific antibodies (HSA) and soluble CD30 (sCD30) were measured in 208 renal transplant recipients with functioning grafts at least 1 year after transplantation (median 8.2 years) to investigate the predictive value of HSA and sCD30 on subsequent graft outcome. HSA (class I and class II) were detected by both ELISA LAT-M and Luminex LabScreen assays. Data on graft outcome was collected with a median follow-up time of 3.5 years after antibody and sCD30 measurement. Recipients with post-transplant HLA class II antibodies had particularly poor graft outcome with a hazard ratio (HR) of 7.8 (p transplant sCD30 level >or=100 U/mL was associated with increased risk of subsequent graft failure (HR 2.7, p = 0.03). sCD30 and HSA had an independent and additive association with graft outcome. Recipients with HLA class II antibody and high sCD30 had the highest risk of subsequent graft failure (HR 43.4, p sCD30 measured at least 1-year post-transplant provides valuable and predictive information regarding subsequent graft outcome.

Psychometric evaluation of the Overexcitability Questionnaire-Two applying Bayesian Structural Equation Modeling (BSEM and multiple-group BSEM-based alignment with approximate measurement invariance

Directory of Open Access Journals (Sweden)

Niki eDe Bondt

2015-12-01

Full Text Available The Overexcitability Questionnaire-Two (OEQ-II measures the degree and nature of overexcitability, which assists in determining the developmental potential of an individual according to Dabrowski’s Theory of Positive Disintegration. Previous validation studies using frequentist confirmatory factor analysis, which postulates exact parameter constraints, led to model rejection and a long series of model modifications. Bayesian structural equation modeling (BSEM allows the application of zero-mean, small-variance priors for cross-loadings, residual covariances, and differences in measurement parameters across groups, better reflecting substantive theory and leading to better model fit and less overestimation of factor correlations. Our BSEM analysis with a sample of 516 students in higher education yields positive results regarding the factorial validity of the OEQ-II. Likewise, applying BSEM-based alignment with approximate measurement invariance, the absence of non-invariant factor loadings and intercepts across gender is supportive of the psychometric quality of the OEQ-II. Compared to males, females scored significantly higher on emotional and sensual overexcitability, and significantly lower on psychomotor overexcitability.

Quantized gauge invariant periodic TDHF solutions

International Nuclear Information System (INIS)

Kan, K.-K.; Griffin, J.J.; Lichtner, P.C.; Dworzecka, M.

1979-01-01

Time-dependent Hartree-Fock (TDHF) is used to study steady state large amplitude nuclear collective motions, such as vibration and rotation. As is well known the small amplitude TDHF leads to the RPA equation. The analysis of periodicity in TDHF is not trivial because TDHF is a nonlinear theory and it is not known under what circumstances a nonlinear theory can support periodic solutions. It is also unknown whether such periodic solution, if they exist, form a continuous or a discrete set. But, these properties may be important in obtaining the energy spectrum of the collective states from the TDHF description. The periodicity and Gauge Invariant Periodicity of solutions are investigated for that class of models whose TDHF solutions depend on time through two parameters. In such models TDHF supports a continuous family of periodic solutions, but only a discrete subset of these is gauge invariant. These discrete Gauge Invariant Periodic solutions obey the Bohr-Summerfeld quantization rule. The energy spectrum of the Gauge Invariant Periodic solutions is compared with the exact eigenergies in one specific example

Tangent unit-vector fields: Nonabelian homotopy invariants and the Dirichlet energy

KAUST Repository

Majumdar, Apala; Robbins, J.M.; Zyskin, Maxim

2009-01-01

energy, E (H), for continuous tangent maps of arbitrary homotopy type H. The expression for E (H) involves a topological invariant - the spelling length - associated with the (nonabelian) fundamental group of the n-times punctured two-sphere, π1 (S2 - {s1

The association of urolithiasis and androgenetic alopecia.

Science.gov (United States)

Resorlu, Mustafa; Sancak, Eyup Burak; Uysal, Fatma; Arslan, Muhammet; Diri, Akif; Adam, Gurhan; Akbas, Alpaslan; Sariyildirim, Abdullah; Gulpinar, Murat Tolga; Resorlu, Berkan

2016-01-01

The objective of this study is to investigate whether patients with androgenetic alopecia were at risk in terms of urinary system stone disease. Patients with no baldness (Hamilton-Norwood Scala [HNS] stage I) were categorized as Group I, those with hair loss in the frontal region (HNS stages II, III, IIIa, and IVa) as Group II, those with hair loss in the vertex region (HNS stage III-vertex, V) as Group III and those with hair loss in both vertex and frontal regions (HNS stages IV, Va, VI, and VII) as Group IV. Patients in all groups were compared in terms of presence of stone, and the presence of any association between alopecia and urolithiasis, with common etiological risk factors, was investigated. Three hundred and two male patients were included in the study. The presence of urolithiasis was detected in 28.9% of patients in Group I; 26.5% of Group II; 36.9% of Group III; and 44.4% of Group IV (p = 0.085). Among patients aged under 60, urinary stone disease was detected in 30.8% of patients in Group I; 26.4% of Group II; 41.2% of Group III; and 53.8% of Group IV (p = 0.001). In patients aged over 60, urolithiasis was detected in 12.5% of patients in Group I; 26.9% of Group II; 32.2% of Group III; and 37.8% of Group IV (p = 0.371). We determined a significant correlation between vertex pattern and total alopecia with urolithiasis in patients younger than 60 years old.

Invariant molecular-dynamics approach to structural phase transitions

International Nuclear Information System (INIS)

Wentzcovitch, R.M.

1991-01-01

Two fictitious Lagrangians to be used in molecular-dynamics simulations with variable cell shape and suitable to study problems like structural phase transitions are introduced. Because they are invariant with respect to the choice of the simulation cell edges and eliminate symmetry breaking associated with the fictitious part of the dynamics, they improve the physical content of numerical simulations that up to now have been done by using Parrinello-Rahman dynamics

Parton densities in quantum chromodynamics. Gauge invariance, path-dependence, and Wilson lines

International Nuclear Information System (INIS)

Cherednikov, Igor O.

2017-01-01

The purpose of this book is to give a systematic pedagogical exposition of the quantitative analysis of Wilson lines and gauge-invariant correlation functions in quantum chromodynamics. Using techniques from the previous volume (Wilson Lines in Quantum Field Theory, 2014), an ab initio methodology is developed and practical tools for its implementation are presented. Emphasis is put on the implications of gauge invariance and path-dependence properties of transverse-momentum dependent parton density functions. The latter are associated with the QCD factorization approach to semi-inclusive hadronic processes, studied at currently operating and planned experimental facilities.

Parton densities in quantum chromodynamics. Gauge invariance, path-dependence, and Wilson lines

Energy Technology Data Exchange (ETDEWEB)

Cherednikov, Igor O. [Antwerpen Univ. (Belgium). Dept. Fysica; Veken, Frederik F. van der [CERN, Geneva (Switzerland)

2017-05-01

The purpose of this book is to give a systematic pedagogical exposition of the quantitative analysis of Wilson lines and gauge-invariant correlation functions in quantum chromodynamics. Using techniques from the previous volume (Wilson Lines in Quantum Field Theory, 2014), an ab initio methodology is developed and practical tools for its implementation are presented. Emphasis is put on the implications of gauge invariance and path-dependence properties of transverse-momentum dependent parton density functions. The latter are associated with the QCD factorization approach to semi-inclusive hadronic processes, studied at currently operating and planned experimental facilities.

An introduction to conformal invariance in quantum field theory and statistical mechanics

International Nuclear Information System (INIS)

Boyanovsky, D.; Naon, C.M.

1990-01-01

The subject of conformal invariance provides an extraordinarly successful and productive symbiosis between statistical mechanics and quantum field theory. The main goal of this paper, which is tailored to a wide audience, is to give an introduction to such vast subject (C.P.)

Multiperiod Maximum Loss is time unit invariant.

Science.gov (United States)

Kovacevic, Raimund M; Breuer, Thomas

2016-01-01

Time unit invariance is introduced as an additional requirement for multiperiod risk measures: for a constant portfolio under an i.i.d. risk factor process, the multiperiod risk should equal the one period risk of the aggregated loss, for an appropriate choice of parameters and independent of the portfolio and its distribution. Multiperiod Maximum Loss over a sequence of Kullback-Leibler balls is time unit invariant. This is also the case for the entropic risk measure. On the other hand, multiperiod Value at Risk and multiperiod Expected Shortfall are not time unit invariant.

A novel sensitive Cu(II) and Cd(II) nanosensor platform: Graphene oxide terminated p-aminophenyl modified glassy carbon surface

International Nuclear Information System (INIS)

Gupta, Vinod Kumar; Yola, Mehmet Lütfi; Atar, Necip; Ustundag, Zafer; Solak, Ali Osman

2013-01-01

Graphical abstract: - Highlights: • We electrochemically prepared sensor based on graphene oxide. • The prepared electrode was characterized by using various techniques. • The proposed nanosensor showed good stability, selectivity and high sensitivity. • The proposed nanosensor electrode was used for the analysis of Cd(II) and Cu(II). - Abstract: Graphene oxide (GO) based glassy carbon (GC) electrode has been prepared. Firstly, p-nitrophenyl (NP) modified GC (NP/GC) electrode was prepared via the electrochemical reduction of its tetraflouroborate diazonium salt. After the formation of NP/GC electrode, the negative potential was applied to NP/GC electrode to reduce the nitro groups to amine. p-Aminophenyl (AP) modified GC (AP/GC) electrode was immersed into a graphene oxide solution containing 1-ethyl-3(3-(dimethlyamino)propyl)-carbodiimide. Hence, we constructed GO terminated AP modified GC (GO/AP/GC) electrode. NP/GC, AP/GC and GO/AP/GC electrodes were characterized sequentially using cyclic voltammetry (CV) in the presence of 1.0 mM of potassium ferricyanide in 0.1 M KCl. In addition, GO and GO/AP/GC surfaces were characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM). The GO/AP/GC electrode was used for the analysis of Cd(II) and Cu(II) ions by adsorptive stripping voltammetry. The linearity range and the detection limit of Cd(II) and Cu(II) ions were 1.0 × 10 −11 –5.0 × 10 −10 M and 3.3 × 10 −12 M (S/N = 3), respectively

Cervical Muscle Dysfunction in the Chronic Whiplash Associated Disorder Grade II (WAD-II)

NARCIS (Netherlands)

Nederhand, Marcus Johannes; IJzerman, Maarten Joost; Hermens, Hermanus J.; Baten, Christian T.M.; Zilvold, Gerrit

2000-01-01

Study Design: In a cross-sectional study, surface electromyography measurements of the upper trapezius muscles were obtained during different functional tasks in patients with a chronic whiplash associated disorder Grade II and healthy control subjects. - Objectives: To investigate whether muscle

Dimuon Level-1 invariant mass in 2017 data

CERN Document Server

CMS Collaboration

2018-01-01

This document shows the Level-1 (L1) dimuon invariant mass with and without L1 muon track extrapolation to the collision vertex and how it compares with the offline reconstructed dimuon invariant mass. The plots are made with the data sample collected in 2017. The event selection, the matching algorithm and the results of the L1 dimuon invariant mass are described in the next pages.

Decrease in scale invariance of activity fluctuations with aging and in patients with suprasellar tumors

DEFF Research Database (Denmark)

Joustra, S. D.; Gu, C.; Rohling, J. H.T.

2018-01-01

-matched healthy controls (age range 21.0–70.6 years). Spontaneous wrist locomotor activity was measured for 7 days with actigraphy, and detrended fluctuation analysis was applied to assess correlations over a range of time scales from minutes to 24 h. For all the subjects, complex scale-invariant correlations...... scale invariance. Conversely, activity patterns at time scales between 10 and 24 h were significantly more regular than all other time scales, and this was mostly associated with age. In conclusion, scale invariance is degraded in healthy subjects at the ages of >33 year as characterized by attenuation......Motor activity in healthy young humans displays intrinsic fluctuations that are scale-invariant over a wide range of time scales (from minutes to hours). Human postmortem and animal lesion studies showed that the intact function of the suprachiasmatic nucleus (SCN) is required to maintain...

On invariant MASAs for endomorphisms of the Cuntz algebras

DEFF Research Database (Denmark)

Hong, Jeong Hee; Skalski, Adam; Szymanski, Wojciech

2010-01-01

The problem of existence of standard (i.e. product-type) invariant MASAs for endomorphisms of the Cuntz algebras O_n is studied. In particular, endomorphisms which preserve the canonical diagonal MASA D_n are investigated. Conditions on a unitary w equivalent to the fact that the corresponding...... endomorphism λ_w preserves D_n are found, and it is shown that they may be satisfied by unitaries which do not normalize D_n. Unitaries giving rise to endomorphisms which leave all standard MASAs invariant and have identical actions on them are characterized. Finally, some properties of examples of finite......-index endomorphisms of O_n given by Izumi and related to sector theory are discussed and it is shown that they lead to an endomorphism of O_2 associated to a matrix unitary which does not preserve any standard MASA....

Harmonic analysis and global solvability of a differential operator invariant on motion groups and semi-simple Lie groups

International Nuclear Information System (INIS)

El-Hussein, K.

1991-08-01

Let V be a real finite dimensional vector space and let K be a connected compact Lie group, which acts on V by means of a continuous linear representation ρ. Let G=V x p K be the motion group which is the semi-direct product of V by K and let P be an invariant differential operator on G. In this paper we give a necessary and sufficient condition for the global solvability of P on G. Now let G be a connected semi-simple Lie group with finite centre and let P be an invariant differential operator on G. We give also a necessary and sufficient condition for the global solvability of P on G. (author). 8 refs

A Balanced Comparison of Object Invariances in Monkey IT Neurons.

Science.gov (United States)

Ratan Murty, N Apurva; Arun, Sripati P

2017-01-01

Our ability to recognize objects across variations in size, position, or rotation is based on invariant object representations in higher visual cortex. However, we know little about how these invariances are related. Are some invariances harder than others? Do some invariances arise faster than others? These comparisons can be made only upon equating image changes across transformations. Here, we targeted invariant neural representations in the monkey inferotemporal (IT) cortex using object images with balanced changes in size, position, and rotation. Across the recorded population, IT neurons generalized across size and position both stronger and faster than to rotations in the image plane as well as in depth. We obtained a similar ordering of invariances in deep neural networks but not in low-level visual representations. Thus, invariant neural representations dynamically evolve in a temporal order reflective of their underlying computational complexity.

Characteristics of coronal mass ejections associated with solar frontside and backside metric type II bursts

International Nuclear Information System (INIS)

Kahler, S.W.; Cliver, E.W.; Sheeley, N.R. Jr.; Howard, R.A.; Koomen, M.J.; Michels, D.J.

1985-01-01

We compare fast (v> or =500 km s -1 ) coronal mass ejections (CME's) with reported metric type II bursts to study the properties of CME's associated with coronal shocks. We confirm an earlier report of fast frontside CME's with no associated metric type II bursts and calculate that 33 +- 15% of all fast frontside CME's are not associated with such bursts. Faster CME's are more likely to be associated with type II bursts, as expected from the hypothesis of piston-driven shocks. However, CME brightness and associated peak 3-cm burst intensity are also important factors, as might be inferred from the Wagner and MacQueen (1983) view of type II shocks decoupled from associated CME's. We use the equal visibility of solar frontside and backside CME's to deduce the observability of backside type II bursts. We calculate that 23 +- 7% of all backside type II bursts associated with fast CME's can be observed at the earth and that 13 +- 4% of all type II bursts originate in backside flares. CME speed again is the most important factor in the observability of backside type II bursts

Construction of an infectious clone of human adenovirus type 41.

Science.gov (United States)

Chen, Duo-Ling; Dong, Liu-Xin; Li, Meng; Guo, Xiao-Juan; Wang, Min; Liu, Xin-Feng; Lu, Zhuo-Zhuang; Hung, Tao

2012-07-01

Human adenovirus type 41 (HAdV-41) is well known for its fastidiousness in cell culture. To construct an infectious clone of HAdV-41, a DNA fragment containing the left and right ends of HAdV-41 as well as a kanamycin resistance gene and a pBR322 replication origin was excised from the previously constructed plasmid pAd41-GFP. Using homologous recombination, the plasmid pKAd41 was generated by co-transformation of the E. coli BJ5183 strain with this fragment and HAdV-41 genomic DNA. Virus was rescued from pKAd41-transfected 293TE7 cells, a HAdV-41 E1B55K-expressing cell line. The genomic integrity of the rescued virus was verified by restriction analysis and sequencing. Two fibers on the virion were confirmed by western blot. Immunofluorescence showed that more expression of the hexon protein could be found in 293TE7 cells than in 293 cells after HAdV-41 infection. The feature of non-lytic replication was preserved in 293TE7 cells, since very few progeny HAdV-41 viruses were released to the culture medium. These results show that pKAd41 is an effective infectious clone and suggest that the combination of pKAd41 and 293TE7 cells is an ideal system for virological study of HAdV-41.

Clinical assessment of class II resin-based composites versus preformed metal crowns performed on primary molars in patients at high risk of caries.

Science.gov (United States)

Alyahya, A; Khanum, A; Qudeimat, M

2018-02-01

To compare class II resin composite with preformed metal crowns (PMC) in the treatment of proximal dentinal caries in high caries-risk patients. The charts (270) of paediatric patients with proximal caries of their primary molars were reviewed. Success or failure of a procedure was assessed using the dental notes. Survival analysis was used to calculate the mean survival time (MST) for both procedures. The influence of variables on the mean survival time was investigated. A total of 593 class II resin composites and 243 PMCs were placed in patients ranging between 4-13 years of age. The failure percentage of class II resin composites was 22.6% with the majority having been due to recurrent caries, while the failure percentage of PMCs was 15.2% with the majority due to loss of the crown. There was no significant difference between the MST of class II resin composites and PMCs, 41.3 and 45.6 months respectively (p value = 0.06). In class II resin composites, mesial restorations were associated with lower MST compared to distal restorations (p-value composites and PMCs were comparable when performed on high caries-risk patients.

Searching for Compact Radio Sources Associated with UCH ii Regions

Energy Technology Data Exchange (ETDEWEB)

Masqué, Josep M.; Trinidad, Miguel A.; Rodríguez-Rico, Carlos A. [Departamento de Astronomía, Universidad de Guanajuato, Apdo. Postal 144, 36000 Guanajuato, México (Mexico); Rodríguez, Luis F.; Kurtz, Stan; Loinard, Laurent [Instituto de Radioastronomía y Astrofísica, Universidad Nacional Autónoma de México, Morelia 58089, México (Mexico); Dzib, Sergio A. [Max Planck Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany)

2017-02-10

Ultra-compact (UC)H ii regions represent a very early stage of massive star formation. The structure and evolution of these regions are not yet fully understood. Interferometric observations showed in recent years that compact sources of uncertain nature are associated with some UCH ii regions. To examine this, we carried out VLA 1.3 cm observations in the A configuration of selected UCH ii regions in order to report additional cases of compact sources embedded in UCH ii regions. With these observations, we find 13 compact sources that are associated with 9 UCH ii regions. Although we cannot establish an unambiguous nature for the newly detected sources, we assess some of their observational properties. According to the results, we can distinguish between two types of compact sources. One type corresponds to sources that are probably deeply embedded in the dense ionized gas of the UCH ii region. These sources are photoevaporated by the exciting star of the region and will last for 10{sup 4}–10{sup 5} years. They may play a crucial role in the evolution of the UCH ii region as the photoevaporated material could replenish the expanding plasma and might provide a solution to the so-called lifetime problem of these regions. The second type of compact sources is not associated with the densest ionized gas of the region. A few of these sources appear resolved and may be photoevaporating objects such as those of the first type, but with significantly lower mass depletion rates. The remaining sources of this second type appear unresolved, and their properties are varied. We speculate on the similarity between the sources of the second type and those of the Orion population of radio sources.

Invariant probabilities of transition functions

CERN Document Server

Zaharopol, Radu

2014-01-01

The structure of the set of all the invariant probabilities and the structure of various types of individual invariant probabilities of a transition function are two topics of significant interest in the theory of transition functions, and are studied in this book. The results obtained are useful in ergodic theory and the theory of dynamical systems, which, in turn, can be applied in various other areas (like number theory). They are illustrated using transition functions defined by flows, semiflows, and one-parameter convolution semigroups of probability measures. In this book, all results on transition probabilities that have been published by the author between 2004 and 2008 are extended to transition functions. The proofs of the results obtained are new. For transition functions that satisfy very general conditions the book describes an ergodic decomposition that provides relevant information on the structure of the corresponding set of invariant probabilities. Ergodic decomposition means a splitting of t...

Riemann quasi-invariants

International Nuclear Information System (INIS)

Pokhozhaev, Stanislav I

2011-01-01

The notion of Riemann quasi-invariants is introduced and their applications to several conservation laws are considered. The case of nonisentropic flow of an ideal polytropic gas is analysed in detail. Sufficient conditions for gradient catastrophes are obtained. Bibliography: 16 titles.

The Measurement Invariance of the Student Opinion Survey across English and non-English Language Learner Students within the Context of Low- and High-Stakes Assessments

Directory of Open Access Journals (Sweden)

Jason C. Immekus

2016-09-01

Full Text Available Student effort on large-scale assessments has important implications on the interpretation and use of scores to guide decisions. Within the United States, English Language Learners (ELLs generally are outperformed on large-scale assessments by non-ELLs, prompting research to examine factors associated with test performance. There is a gap in the literature regarding the test-taking motivation of ELLs compared to non-ELLs and whether existing measures have similar psychometric properties across groups. The Student Opinion Survey (SOS; Sundre, 2007 was designed to be administered after completion of a large-scale assessment to operationalize students’ test-taking motivation. Based on data obtained on 5,257 (41.8% ELL 10th grade students, study purpose was to test the measurement invariance of the SOS across ELLs and non-ELLs based on completion of low- and high-stakes assessments. Preliminary item analyses supported the removal of two SOS items (Items 3 and 7 that resulted in improved internal consistency for each of the two SOS subscales: Importance, Effort. A subsequent multi-sample confirmatory factor analysis (MCFA supported the measurement invariance of the scale’s two-factor model across language groups, indicating it met strict factorial invariance (Meredith 1993. A follow-up latent means analysis found that ELLs had higher effort on both the low- and high-stakes assessment with a small effect size. Effect size estimates indicated negligible differences on the importance factor. Although the instrument can be expected to function similarly across diverse language groups, which may have direct utility of test users and research into factors associated with large-scale test performance, continued research is recommended. Implications for SOS use in applied and research settings are discussed.

Modular categories and 3-manifold invariants

International Nuclear Information System (INIS)

Tureav, V.G.

1992-01-01

The aim of this paper is to give a concise introduction to the theory of knot invariants and 3-manifold invariants which generalize the Jones polynomial and which may be considered as a mathematical version of the Witten invariants. Such a theory was introduced by N. Reshetikhin and the author on the ground of the theory of quantum groups. here we use more general algebraic objects, specifically, ribbon and modular categories. Such categories in particular arise as the categories of representations of quantum groups. The notion of modular category, interesting in itself, is closely related to the notion of modular tensor category in the sense of G. Moore and N. Seiberg. For simplicity we restrict ourselves in this paper to the case of closed 3-manifolds

Knot invariants and higher representation theory

CERN Document Server

Webster, Ben

2018-01-01

The author constructs knot invariants categorifying the quantum knot variants for all representations of quantum groups. He shows that these invariants coincide with previous invariants defined by Khovanov for \\mathfrak{sl}_2 and \\mathfrak{sl}_3 and by Mazorchuk-Stroppel and Sussan for \\mathfrak{sl}_n. The author's technique is to study 2-representations of 2-quantum groups (in the sense of Rouquier and Khovanov-Lauda) categorifying tensor products of irreducible representations. These are the representation categories of certain finite dimensional algebras with an explicit diagrammatic presentation, generalizing the cyclotomic quotient of the KLR algebra. When the Lie algebra under consideration is \\mathfrak{sl}_n, the author shows that these categories agree with certain subcategories of parabolic category \\mathcal{O} for \\mathfrak{gl}_k.

Existence of a last invariant of conservative motion

International Nuclear Information System (INIS)

Hall, L.S.

1982-01-01

A general theory of integrable systems in two dimensions is formulated and applied. (The theory also has applications to more dimensions). The constraints are found which admit to general integrability of the orbits for magnetic forces as well as for forces derivable from a potential. When a system admits a given invariant, the invariant is found. A number of examples including known and apparently previously unknown invariants are given. The theory of exact integrals of the motion also can be extended to the derivation of approximate invariants. The general theory admits a variational principle, among other approximation techniques, for the computation of a best approximate invariant. The problem of the general cubic potential with one symmetric coordinate, V = 1/2 Ax 2 + 1/2 By 2 + Cx 2 y + 1/3 Dy 3 (of which the well-studied Henon-Heiles potential is the special case for A = B and C = -D), is examined in detail

Knot invariants derived from quandles and racks

OpenAIRE

Kamada, Seiichi

2002-01-01

The homology and cohomology of quandles and racks are used in knot theory: given a finite quandle and a cocycle, we can construct a knot invariant. This is a quick introductory survey to the invariants of knots derived from quandles and racks.

Fermions and link invariants

International Nuclear Information System (INIS)

Kauffman, L.; Saleur, H.

1991-01-01

Various aspects of knot theory are discussed when fermionic degrees of freedom are taken into account in the braid group representations and in the state models. It is discussed how the R matrix for the Alexander polynomial arises from the Fox differential calculus, and how it is related to the quantum group U q gl(1,1). New families of solutions of the Yang Baxter equation obtained from ''linear'' representations of the braid group and exterior algebra are investigated. State models associated with U q sl(n,m), and in the case n=m=1 a state model for the multivariable Alexander polynomial are studied. Invariants of links in solid handlebodies are considered and it is shown how the non trivial topology lifts the boson fermion degeneracy is present in S 3 . (author) 36 refs

A novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans.

Science.gov (United States)

Pellegrino, Renata; Kavakli, Ibrahim Halil; Goel, Namni; Cardinale, Christopher J; Dinges, David F; Kuna, Samuel T; Maislin, Greg; Van Dongen, Hans P A; Tufik, Sergio; Hogenesch, John B; Hakonarson, Hakon; Pack, Allan I

2014-08-01

Earlier work described a mutation in DEC2 also known as BHLHE41 (basic helix-loophelix family member e41) as causal in a family of short sleepers, who needed just 6 h sleep per night. We evaluated whether there were other variants of this gene in two well-phenotyped cohorts. Sequencing of the BHLHE41 gene, electroencephalographic data, and delta power analysis and functional studies using cell-based luciferase. We identified new variants of the BHLHE41 gene in two cohorts who had either acute sleep deprivation (n = 200) or chronic partial sleep deprivation (n = 217). One variant, Y362H, at another location in the same exon occurred in one twin in a dizygotic twin pair and was associated with reduced sleep duration, less recovery sleep following sleep deprivation, and fewer performance lapses during sleep deprivation than the homozygous twin. Both twins had almost identical amounts of non rapid eye movement (NREM) sleep. This variant reduced the ability of BHLHE41 to suppress CLOCK/BMAL1 and NPAS2/BMAL1 transactivation in vitro. Another variant in the same exome had no effect on sleep or response to sleep deprivation and no effect on CLOCK/BMAL1 transactivation. Random mutagenesis identified a number of other variants of BHLHE41 that affect its function. There are a number of mutations of BHLHE41. Mutations reduce total sleep while maintaining NREM sleep and provide resistance to the effects of sleep loss. Mutations that affect sleep also modify the normal inhibition of BHLHE41 of CLOCK/BMAL1 transactivation. Thus, clock mechanisms are likely involved in setting sleep length and the magnitude of sleep homeostasis. Pellegrino R, Kavakli IH, Goel N, Cardinale CJ, Dinges DF, Kuna ST, Maislin G, Van Dongen HP, Tufik S, Hogenesch JB, Hakonarson H, Pack AI. A novel BHLHE41 variant is associated with short sleep and resistance to sleep deprivation in humans. SLEEP 2014;37(8):1327-1336.

Invariant approach to CP in unbroken Δ(27

Directory of Open Access Journals (Sweden)

Gustavo C. Branco

2015-10-01

Full Text Available The invariant approach is a powerful method for studying CP violation for specific Lagrangians. The method is particularly useful for dealing with discrete family symmetries. We focus on the CP properties of unbroken Δ(27 invariant Lagrangians with Yukawa-like terms, which proves to be a rich framework, with distinct aspects of CP, making it an ideal group to investigate with the invariant approach. We classify Lagrangians depending on the number of fields transforming as irreducible triplet representations of Δ(27. For each case, we construct CP-odd weak basis invariants and use them to discuss the respective CP properties. We find that CP violation is sensitive to the number and type of Δ(27 representations.

Inertial Spontaneous Symmetry Breaking and Quantum Scale Invariance

Energy Technology Data Exchange (ETDEWEB)

Ferreira, Pedro G. [Oxford U.; Hill, Christopher T. [Fermilab; Ross, Graham G. [Oxford U., Theor. Phys.

2018-01-23

Weyl invariant theories of scalars and gravity can generate all mass scales spontaneously, initiated by a dynamical process of "inertial spontaneous symmetry breaking" that does not involve a potential. This is dictated by the structure of the Weyl current, $K_\\mu$, and a cosmological phase during which the universe expands and the Einstein-Hilbert effective action is formed. Maintaining exact Weyl invariance in the renormalised quantum theory is straightforward when renormalisation conditions are referred back to the VEV's of fields in the action of the theory, which implies a conserved Weyl current. We do not require scale invariant regulators. We illustrate the computation of a Weyl invariant Coleman-Weinberg potential.

Membrane-associated 41-kDa GTP-binding protein in collagen-induced platelet activation

International Nuclear Information System (INIS)

Walker, G.; Bourguignon, L.Y.

1990-01-01

Initially we established that the binding of collagen to human blood platelets stimulates both the rapid loss of PIP2 and the generation of inositol-4,5-bisphosphate (IP2) and inositol-1,4,5-triphosphate (IP3). These results indicate that the binding of collagen stimulates inositol phospholipid-specific phospholipase C during platelet activation. The fact that GTP or GTP-gamma-S augments, and pertussis toxin inhibits, collagen-induced IP3 formation suggests that a GTP-binding protein or (or proteins) may be directly involved in the regulation of phospholipase C-mediated phosphoinositide turnover in human platelets. We have used several complementary techniques to isolate and characterize a platelet 41-kDa polypeptide (or polypeptides) that has a number of structural and functional similarities to the regulatory alpha i subunit of the GTP-binding proteins isolated from bovine brain. This 41-kDa polypeptide (or polypeptides) is found to be closely associated with at least four membrane glycoproteins (e.g., gp180, gp110, gp95, and gp75) in a 330-kDa complex that can be dissociated by treatment with high salt plus urea. Most important, we have demonstrated that antilymphoma 41-kDa (alpha i subunit of GTP-binding proteins) antibody cross-reacts with the platelet 41-kDa protein (or proteins) and the alpha i subunit of bovine brain Gi alpha proteins, and blocks GTP/collagen-induced IP3 formation. These data provide strong evidence that the 41-kDa platelet GTP-binding protein (or proteins) is directly involved in collagen-induced signal transduction during platelet activation

Membrane-associated 41-kDa GTP-binding protein in collagen-induced platelet activation

Energy Technology Data Exchange (ETDEWEB)

Walker, G.; Bourguignon, L.Y. (Univ. of Miami Medical School, FL (USA))

1990-08-01

Initially we established that the binding of collagen to human blood platelets stimulates both the rapid loss of PIP2 and the generation of inositol-4,5-bisphosphate (IP2) and inositol-1,4,5-triphosphate (IP3). These results indicate that the binding of collagen stimulates inositol phospholipid-specific phospholipase C during platelet activation. The fact that GTP or GTP-gamma-S augments, and pertussis toxin inhibits, collagen-induced IP3 formation suggests that a GTP-binding protein or (or proteins) may be directly involved in the regulation of phospholipase C-mediated phosphoinositide turnover in human platelets. We have used several complementary techniques to isolate and characterize a platelet 41-kDa polypeptide (or polypeptides) that has a number of structural and functional similarities to the regulatory alpha i subunit of the GTP-binding proteins isolated from bovine brain. This 41-kDa polypeptide (or polypeptides) is found to be closely associated with at least four membrane glycoproteins (e.g., gp180, gp110, gp95, and gp75) in a 330-kDa complex that can be dissociated by treatment with high salt plus urea. Most important, we have demonstrated that antilymphoma 41-kDa (alpha i subunit of GTP-binding proteins) antibody cross-reacts with the platelet 41-kDa protein (or proteins) and the alpha i subunit of bovine brain Gi alpha proteins, and blocks GTP/collagen-induced IP3 formation. These data provide strong evidence that the 41-kDa platelet GTP-binding protein (or proteins) is directly involved in collagen-induced signal transduction during platelet activation.

Removal of Cu(II) and Pb(II) from Aqueous Solutions Using Nanoporous Materials

Science.gov (United States)

Dutta, Debajani; Roy, Sushanta Kumar; Das, Bodhaditya; Talukdar, Anup K.

2018-05-01

The present work deals with the adsorption of Cu2+ and Pb2+ on zeolites (ZSM-5, mordenite) and mesoporous materials (MCM-48, MCM-41). The characterization of the synthesized samples was performed by means of XRD, SEM, and thermogravimetric analysis. The batch method was employed to study the influence of adsorbent nature, contact time, initial metal ion concentration, and adsorbent load. The adsorption on MCM-48 follows a pseudo-second-order kinetic model. This material was found to be more effective for the removal of lead in a batch process as compared to the other adsorbents and the removal efficiency of the materials for Pb(II) followed the order MCM-48 > mordenite > ZSM-5 > MCM-41 and that for Cu(II) followed the order ZSM-5 > mordenite > MCM-41 > MCM-48.

Safflor yellow B suppresses angiotensin II-mediated human umbilical vein cell injury via regulation of Bcl-2/p22phox expression

International Nuclear Information System (INIS)

Wang, Chaoyun; He, Yanhao; Yang, Ming; Sun, Hongliu; Zhang, Shuping; Wang, Chunhua

2013-01-01

Intracellular reactive oxygen species (ROS) are derived from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase. Angiotensin II (Ang II) can cause endothelial dysfunction by promoting intracellular ROS generation. Safflor yellow B (SYB) effectively inhibits ROS generation by upregulating Bcl-2 expression. In this study, we examined the effects of SYB on Ang II-induced injury to human umbilical vein endothelial cells (HUVECs), and elucidated the roles of NADPH oxidase and Bcl-2. We treated cultured HUVECs with Ang II, SYB, and Bcl-2 siRNA, and determined NADPH oxidase activity and ROS levels. Furthermore, cellular and mitochondrial physiological states were evaluated, and the expression levels of target proteins were analyzed. Ang II significantly enhanced intracellular ROS levels, caused mitochondrial membrane dysfunction, and decreased cell viability, leading to apoptosis. This was associated with increased expression of AT1R and p22 phox , increased NADPH oxidase activity, and an increased ratio of Bax/Bcl-2, leading to decreases in antioxidant enzyme activities, which were further strengthened after blocking Bcl-2. Compared to Ang II treatment alone, co-treatment with SYB significantly reversed HUVEC injury. Taken together, these results demonstrate that SYB could significantly protect endothelial cells from Ang II-induced cell damage, and that it does so by upregulating Bcl-2 expression and inhibiting ROS generation. - Highlights: • Angiotensin II depresses mitochondria physiological function. • Angiotensin II activates NADPH oxidase via up-regulating expresion of p22 phox . • Bcl-2 plays a pivotal role in improving mitochondria function and regulates ROS level. • Inhibitor of Bcl-2 promotes angiotensin II mediated HUVEC injury. • SYB attenuates angiotensin II mediated HUVEC injury via up regulating Bcl-2 expression

OPATs: Omnibus P-value association tests.

Science.gov (United States)

Chen, Chia-Wei; Yang, Hsin-Chou

2017-07-10

Combining statistical significances (P-values) from a set of single-locus association tests in genome-wide association studies is a proof-of-principle method for identifying disease-associated genomic segments, functional genes and biological pathways. We review P-value combinations for genome-wide association studies and introduce an integrated analysis tool, Omnibus P-value Association Tests (OPATs), which provides popular analysis methods of P-value combinations. The software OPATs programmed in R and R graphical user interface features a user-friendly interface. In addition to analysis modules for data quality control and single-locus association tests, OPATs provides three types of set-based association test: window-, gene- and biopathway-based association tests. P-value combinations with or without threshold and rank truncation are provided. The significance of a set-based association test is evaluated by using resampling procedures. Performance of the set-based association tests in OPATs has been evaluated by simulation studies and real data analyses. These set-based association tests help boost the statistical power, alleviate the multiple-testing problem, reduce the impact of genetic heterogeneity, increase the replication efficiency of association tests and facilitate the interpretation of association signals by streamlining the testing procedures and integrating the genetic effects of multiple variants in genomic regions of biological relevance. In summary, P-value combinations facilitate the identification of marker sets associated with disease susceptibility and uncover missing heritability in association studies, thereby establishing a foundation for the genetic dissection of complex diseases and traits. OPATs provides an easy-to-use and statistically powerful analysis tool for P-value combinations. OPATs, examples, and user guide can be downloaded from http://www.stat.sinica.edu.tw/hsinchou/genetics/association/OPATs.htm. © The Author 2017

Coordination and Oxidation States of Iron Incorporated in Mesoporous MCM41

International Nuclear Information System (INIS)

Lazar, K.; Pal-Borbely, G.; Szegedi, A.; Beyer, H. K.

2002-01-01

Mesoporous Fe-MCM41 samples (Si/Fe=25) were synthesized and characterized under evacuation and reducing/oxidizing treatments by in situ FTIR and Moessbauer spectroscopies. Both Fe(II) and Fe(III) located in low coordination states in top layers of pore walls exhibit Lewis acidity and may participate in Fe(III) ↔ Fe(II) processes at low temperatures (570 K). Furthermore, Fe(III) ↔ Fe(II) cycles can be achieved and repeated with participation of the full amount of iron at higher temperatures (670 K). The accompanying formation of oxygen vacancies and restoration of the structure in the reverse process does not result in extended damages; the MCM41 structure retains its stability under the conditions applied.

Invariance as a Tool for Ontology of Information

Directory of Open Access Journals (Sweden)

Marcin J. Schroeder

2016-03-01

Full Text Available Attempts to answer questions regarding the ontological status of information are frequently based on the assumption that information should be placed within an already existing framework of concepts of established ontological statuses related to science, in particular to physics. However, many concepts of physics have undetermined or questionable ontological foundations. We can look for a solution in the recognition of the fundamental role of invariance with respect to a change of reference frame and to other transformations as a criterion for objective existence. The importance of invariance (symmetry as a criterion for a primary ontological status can be identified in the methodology of physics from its beginnings in the work of Galileo, to modern classifications of elementary particles. Thus, the study of the invariance of the theoretical description of information is proposed as the first step towards ontology of information. With the exception of only a few works among publications which set the paradigm of information studies, the issues of invariance were neglected. Orthodox analysis of information lacks conceptual framework for the study of invariance. The present paper shows how invariance can be formalized for the definition of information and, accompanying it, mathematical formalism proposed by the author in his earlier publications.

How does the brain rapidly learn and reorganize view-invariant and position-invariant object representations in the inferotemporal cortex?

Science.gov (United States)

Cao, Yongqiang; Grossberg, Stephen; Markowitz, Jeffrey

2011-12-01

All primates depend for their survival on being able to rapidly learn about and recognize objects. Objects may be visually detected at multiple positions, sizes, and viewpoints. How does the brain rapidly learn and recognize objects while scanning a scene with eye movements, without causing a combinatorial explosion in the number of cells that are needed? How does the brain avoid the problem of erroneously classifying parts of different objects together at the same or different positions in a visual scene? In monkeys and humans, a key area for such invariant object category learning and recognition is the inferotemporal cortex (IT). A neural model is proposed to explain how spatial and object attention coordinate the ability of IT to learn invariant category representations of objects that are seen at multiple positions, sizes, and viewpoints. The model clarifies how interactions within a hierarchy of processing stages in the visual brain accomplish this. These stages include the retina, lateral geniculate nucleus, and cortical areas V1, V2, V4, and IT in the brain's What cortical stream, as they interact with spatial attention processes within the parietal cortex of the Where cortical stream. The model builds upon the ARTSCAN model, which proposed how view-invariant object representations are generated. The positional ARTSCAN (pARTSCAN) model proposes how the following additional processes in the What cortical processing stream also enable position-invariant object representations to be learned: IT cells with persistent activity, and a combination of normalizing object category competition and a view-to-object learning law which together ensure that unambiguous views have a larger effect on object recognition than ambiguous views. The model explains how such invariant learning can be fooled when monkeys, or other primates, are presented with an object that is swapped with another object during eye movements to foveate the original object. The swapping procedure is

Remote sensing depth invariant index parameters in shallow benthic habitats for bottom type classification.

Science.gov (United States)

Gapper, J.; El-Askary, H. M.; Linstead, E.

2017-12-01

Ground cover prediction of benthic habitats using remote sensing imagery requires substantial feature engineering. Artifacts that confound the ground cover characteristics must be severely reduced or eliminated while the distinguishing features must be exposed. In particular, the impact of wavelength attenuation in the water column means that a machine learning algorithm will primarily detect depth. However, the per pixel depths are difficult to know on a grand scale. Previous research has taken an in situ approach to applying depth invariant index on a small area of interest within a Landsat 8 scene. We aim to abstract this process for application to entire Landsat scene as well as other locations in order to study change detection in shallow benthic zones on a global scale. We have developed a methodology and applied it to more than 25 different Landsat 8 scenes. The images were first preprocessed to mask land, clouds, and other distortions then atmospheric correction via dark pixel subtraction was applied. Finally, depth invariant indices were calculated for each location and associated parameters recorded. Findings showed how robust the resulting parameters (deep-water radiance, depth invariant constant, band radiance variance/covariance, and ratio of attenuation) were across all scenes. We then created false color composite images of the depth invariant indices for each location. We noted several artifacts within some sites in the form of patterns or striations that did not appear to be aligned with variations in subsurface ground cover types. Further research into depth surveys for these sites revealed depths consistent with one or more wavelengths fully attenuating. This result showed that our model framework is generalizing well but limited to the penetration depths due to wavelength attenuation. Finally, we compared the parameters associated with the depth invariant calculation which were consistent across most scenes and explained any outliers observed

Could solitons be adiabatic invariants attached to certain non linear equations

International Nuclear Information System (INIS)

Lochak, P.

1984-01-01

Arguments are given to support the claim that solitons should be the adiabatic invariants associated to certain non linear partial differential equations; a precise mathematical form of this conjecture is then stated. As a particular case of the conjecture, the Korteweg-de Vries equation is studied. (Auth.)

Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12 in familial hyperaldosteronism type II.

Science.gov (United States)

Jeske, Y W A; So, A; Kelemen, L; Sukor, N; Willys, C; Bulmer, B; Gordon, R D; Duffy, D; Stowasser, M

2008-04-01

1. There are two types of familial hyperaldosteronism (FH): FH-I and FH-II. FH-I is caused by a hybrid CYP11B1/CYP11B2 gene mutation. The genetic cause of FH-II, which is more common, is unknown. Adrenal hyperplasia and adenomas are features. We previously reported linkage of FH-II to a approximately 5 Mb region on chromosome 7p22. We subsequently reported finding no causative mutations in the retinoblastoma-associated Kruppel-associated box gene (RBaK), a candidate at 7p22 involved in tumorigenesis and cell cycle control. 2. In the current study we investigated RBaK regulatory regions and two other candidate genes: postmeiotic segregation increased 2 (PMS2, involved in DNA mismatch repair and tumour predisposition) and guanine nucleotide-binding protein alpha-12 (GNA12, a transforming oncogene). 3. The GNA12 and PMS2 genes were examined in two affected (A1, A2) and two unaffected (U1, U2) subjects from a large 7p22-linked FH-II family (family 1). No mutations were found. 4. The RBaK and PMS2 distal promoters were sequenced to -2150 bp from the transcription start site for RBaK and-2800 bp for PMS2. Five unreported single nucleotide polymorphisms (SNPs) were found in subjects A1, A2 but not in U1 or U2; A(-2031 bp)T, T(-2030 bp)G, G(-834 bp)C, C(-821 bp)G in RBaK and A(-876 bp)G in PMS2. Additional affected and unaffected subjects from family 1 and from two other 7p22-linked FH-II families and 58 unrelated normotensive control subjects were genotyped for these SNPs. 5. The five novel SNPs were found to be present in a significant proportion of normotensive controls. The four RBaK promoter SNPs were found to be in linkage disequilibrium in the normal population. The RBaK promoter (-)2031T/2030G/834C/821T allele was found to be in linkage disequilibrium with the causative mutation in FH-II family 1, but not in families 2 and 3. The PMS2 promoter (-)876G allele was also found to be linked to affected phenotypes in family 1. 6. The RBaK and PMS2 promoter SNPs alter the

Slow feature analysis: unsupervised learning of invariances.

Science.gov (United States)

Wiskott, Laurenz; Sejnowski, Terrence J

2002-04-01

Invariant features of temporally varying signals are useful for analysis and classification. Slow feature analysis (SFA) is a new method for learning invariant or slowly varying features from a vectorial input signal. It is based on a nonlinear expansion of the input signal and application of principal component analysis to this expanded signal and its time derivative. It is guaranteed to find the optimal solution within a family of functions directly and can learn to extract a large number of decorrelated features, which are ordered by their degree of invariance. SFA can be applied hierarchically to process high-dimensional input signals and extract complex features. SFA is applied first to complex cell tuning properties based on simple cell output, including disparity and motion. Then more complicated input-output functions are learned by repeated application of SFA. Finally, a hierarchical network of SFA modules is presented as a simple model of the visual system. The same unstructured network can learn translation, size, rotation, contrast, or, to a lesser degree, illumination invariance for one-dimensional objects, depending on only the training stimulus. Surprisingly, only a few training objects suffice to achieve good generalization to new objects. The generated representation is suitable for object recognition. Performance degrades if the network is trained to learn multiple invariances simultaneously.

Normal Anti-Invariant Submanifolds of Paraquaternionic Kähler Manifolds

Directory of Open Access Journals (Sweden)

Novac-Claudiu Chiriac

2006-12-01

Full Text Available We introduce normal anti-invariant submanifolds of paraquaternionic Kähler manifolds and study the geometric structures induced on them. We obtain necessary and sufficient conditions for the integrability of the distributions defined on a normal anti-invariant submanifold. Also, we present characterizations of local (global anti-invariant products.

Perturbation to Unified Symmetry and Adiabatic Invariants for Relativistic Hamilton Systems

International Nuclear Information System (INIS)

Zhang Mingjiang; Fang Jianhui; Lu Kai; Pang Ting; Lin Peng

2009-01-01

Based on the concept of adiabatic invariant, the perturbation to unified symmetry and adiabatic invariants for relativistic Hamilton systems are studied. The definition of the perturbation to unified symmetry for the system is presented, and the criterion of the perturbation to unified symmetry is given. Meanwhile, the Noether adiabatic invariants, the generalized Hojman adiabatic invariants, and the Mei adiabatic invariants for the perturbed system are obtained. (general)

Simple tests for CP or P violation by sequential decays: V1V2 modes with decays into l-bar/sub A/l/sub B/ and/or q-bar/sub A/q/sub B/

International Nuclear Information System (INIS)

Dell'Aquila, J.R.; Nelson, C.A.

1986-01-01

In a phiJ, JJ, or JUPSILON decay channel sin 2phi and/or sin phi terms in the azimuthal distribution would imply that P and CP separately are violated. Similarly in a phiZ 0 , JZ 0 , Z 0 Z 0 , or W + W - decay channel sin 2phi terms would imply that CP is violated. For these latter modes there are several distinct α and γ signatures for CP violation. Analogous signatures for expected P violation occur in a charged phiW +- , JW +- , or Z 0 W +- decay channel. Stronger tests for violations occur when the two vector bosons are identical and the X has odd spin because for J = 1 (>1) there are only two (three) independent amplitudes. For X of spin 0 many signatures and consistency checks are tabulated for (i) the violation of both P invariance and CP invariance in a phirho 0 , phiphi, K/sup asterisk+/K/sup asterisk-/, phiJ, JJ, or JUPSILON decay channel, for (ii) the violation of CP invariance in a phiZ 0 , JZ 0 , Z 0 Z 0 , or W + W - decay channel, and for (iii) the expected violation of P invariance in a charged phiW +- , JW +- , or Z 0 W +- decay channel

Terminal hemimyelocystocele associated with Chiari II malformation

Directory of Open Access Journals (Sweden)

Umamaheswara Reddy V.

2014-06-01

Full Text Available Terminal myelocystocele (TMC results from failure of embryonic CSF to drain outside the neural tube creating CSF reservoir within a dorsal meningocele. Association of Chiari II malformation with diastematomyelia and myelocystocele is extremely rare. Myelocystoceles do not have neural tissue so they have good prognosis after treatment, however when associated with hydromelia and Chiari malformation they present with neurological deficits. We present details of a 2 year old female who presented to us with this rare anomaly.

Invariant length scale in relativistic kinematics: lessons from Dirichlet branes

International Nuclear Information System (INIS)

Schuller, Frederic P.; Pfeiffer, Hendryk

2004-01-01

Dirac-Born-Infeld theory is shown to possess a hidden invariance associated with its maximal electric field strength. The local Lorentz symmetry O(1,n) on a Dirichlet-n-brane is thereby enhanced to an O(1,n)xO(1,n) gauge group, encoding both an invariant velocity and acceleration (or length) scale. The presence of this enlarged gauge group predicts consequences for the kinematics of observers on Dirichlet branes, with admissible accelerations being bounded from above. An important lesson is that the introduction of a fundamental length scale into relativistic kinematics does not enforce a deformation of Lorentz boosts, as one might assume naively. The exhibited structures further show that Moffat's non-symmetric gravitational theory qualifies as a candidate for a consistent Born-Infeld type gravity with regulated solutions

Scale invariant for one-sided multivariate likelihood ratio tests

Directory of Open Access Journals (Sweden)

Samruam Chongcharoen

2010-07-01

Full Text Available Suppose 1 2 , ,..., n X X X is a random sample from Np ( ,V distribution. Consider 0 1 2 : ... 0 p H      and1 : 0 for 1, 2,..., i H   i  p , let 1 0 H  H denote the hypothesis that 1 H holds but 0 H does not, and let ~ 0 H denote thehypothesis that 0 H does not hold. Because the likelihood ratio test (LRT of 0 H versus 1 0 H  H is complicated, severalad hoc tests have been proposed. Tang, Gnecco and Geller (1989 proposed an approximate LRT, Follmann (1996 suggestedrejecting 0 H if the usual test of 0 H versus ~ 0 H rejects 0 H with significance level 2 and a weighted sum of the samplemeans is positive, and Chongcharoen, Singh and Wright (2002 modified Follmann’s test to include information about thecorrelation structure in the sum of the sample means. Chongcharoen and Wright (2007, 2006 give versions of the Tang-Gnecco-Geller tests and Follmann-type tests, respectively, with invariance properties. With LRT’s scale invariant desiredproperty, we investigate its powers by using Monte Carlo techniques and compare them with the tests which we recommendin Chongcharoen and Wright (2007, 2006.

Dark coupling and gauge invariance

International Nuclear Information System (INIS)

Gavela, M.B.; Honorez, L. Lopez; Mena, O.; Rigolin, S.

2010-01-01

We study a coupled dark energy-dark matter model in which the energy-momentum exchange is proportional to the Hubble expansion rate. The inclusion of its perturbation is required by gauge invariance. We derive the linear perturbation equations for the gauge invariant energy density contrast and velocity of the coupled fluids, and we determine the initial conditions. The latter turn out to be adiabatic for dark energy, when assuming adiabatic initial conditions for all the standard fluids. We perform a full Monte Carlo Markov Chain likelihood analysis of the model, using WMAP 7-year data

Dark Coupling and Gauge Invariance

CERN Document Server

Gavela, M B; Mena, O; Rigolin, S

2010-01-01

We study a coupled dark energy-dark matter model in which the energy-momentum exchange is proportional to the Hubble expansion rate. The inclusion of its perturbation is required by gauge invariance. We derive the linear perturbation equations for the gauge invariant energy density contrast and velocity of the coupled fluids, and we determine the initial conditions. The latter turn out to be adiabatic for dark energy, when assuming adiabatic initial conditions for all the standard fluids. We perform a full Monte Carlo Markov Chain likelihood analysis of the model, using WMAP 7-year data.

Spin foam diagrammatics and topological invariance

International Nuclear Information System (INIS)

Girelli, Florian; Oeckl, Robert; Perez, Alejandro

2002-01-01

We provide a simple proof of the topological invariance of the Turaev-Viro model (corresponding to simplicial 3D pure Euclidean gravity with cosmological constant) by means of a novel diagrammatic formulation of the state sum models for quantum BF theories. Moreover, we prove the invariance under more general conditions allowing the state sum to be defined on arbitrary cellular decompositions of the underlying manifold. Invariance is governed by a set of identities corresponding to local gluing and rearrangement of cells in the complex. Due to the fully algebraic nature of these identities our results extend to a vast class of quantum groups. The techniques introduced here could be relevant for investigating the scaling properties of non-topological state sums, proposed as models of quantum gravity in 4D, under refinement of the cellular decomposition

Second-order gauge-invariant perturbations during inflation

International Nuclear Information System (INIS)

Finelli, F.; Marozzi, G.; Vacca, G. P.; Venturi, G.

2006-01-01

The evolution of gauge invariant second-order scalar perturbations in a general single field inflationary scenario are presented. Different second-order gauge-invariant expressions for the curvature are considered. We evaluate perturbatively one of these second order curvature fluctuations and a second-order gauge-invariant scalar field fluctuation during the slow-roll stage of a massive chaotic inflationary scenario, taking into account the deviation from a pure de Sitter evolution and considering only the contribution of super-Hubble perturbations in mode-mode coupling. The spectra resulting from their contribution to the second order quantum correlation function are nearly scale-invariant, with additional logarithmic corrections with respect to the first order spectrum. For all scales of interest the amplitude of these spectra depends on the total number of e-folds. We find, on comparing first and second order perturbation results, an upper limit to the total number of e-folds beyond which the two orders are comparable

Modified dispersion relations, inflation, and scale invariance

Science.gov (United States)

Bianco, Stefano; Friedhoff, Victor Nicolai; Wilson-Ewing, Edward

2018-02-01

For a certain type of modified dispersion relations, the vacuum quantum state for very short wavelength cosmological perturbations is scale-invariant and it has been suggested that this may be the source of the scale-invariance observed in the temperature anisotropies in the cosmic microwave background. We point out that for this scenario to be possible, it is necessary to redshift these short wavelength modes to cosmological scales in such a way that the scale-invariance is not lost. This requires nontrivial background dynamics before the onset of standard radiation-dominated cosmology; we demonstrate that one possible solution is inflation with a sufficiently large Hubble rate, for this slow roll is not necessary. In addition, we also show that if the slow-roll condition is added to inflation with a large Hubble rate, then for any power law modified dispersion relation quantum vacuum fluctuations become nearly scale-invariant when they exit the Hubble radius.

Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II

Directory of Open Access Journals (Sweden)

Aaron C. Petrey

2012-03-01

The severe pediatric disorder mucolipidosis II (ML-II; also known as I-cell disease is caused by defects in mannose 6-phosphate (Man-6-P biosynthesis. Patients with ML-II exhibit multiple developmental defects, including skeletal, craniofacial and joint abnormalities. To date, the molecular mechanisms that underlie these clinical manifestations are poorly understood. Taking advantage of a zebrafish model of ML-II, we previously showed that the cartilage morphogenesis defects in this model are associated with altered chondrocyte differentiation and excessive deposition of type II collagen, indicating that aspects of development that rely on proper extracellular matrix homeostasis are sensitive to decreases in Man-6-P biosynthesis. To further investigate the molecular bases for the cartilage phenotypes, we analyzed the transcript abundance of several genes in chondrocyte-enriched cell populations isolated from wild-type and ML-II zebrafish embryos. Increased levels of cathepsin and matrix metalloproteinase (MMP transcripts were noted in ML-II cell populations. This increase in transcript abundance corresponded with elevated and sustained activity of several cathepsins (K, L and S and MMP-13 during early development. Unlike MMP-13, for which higher levels of protein were detected, the sustained activity of cathepsin K at later stages seemed to result from its abnormal processing and activation. Inhibition of cathepsin K activity by pharmacological or genetic means not only reduced the activity of this enzyme but led to a broad reduction in additional protease activity, significant correction of the cartilage morphogenesis phenotype and reduced type II collagen staining in ML-II embryos. Our findings suggest a central role for excessive cathepsin K activity in the developmental aspects of ML-II cartilage pathogenesis and highlight the utility of the zebrafish system to address the biochemical underpinnings of metabolic disease.

Real-time trajectory analysis using stacked invariance methods

OpenAIRE

Kitts, B.

1998-01-01

Invariance methods are used widely in pattern recognition as a preprocessing stage before algorithms such as neural networks are applied to the problem. A pattern recognition system has to be able to recognise objects invariant to scale, translation, and rotation. Presumably the human eye implements some of these preprocessing transforms in making sense of incoming stimuli, for example, placing signals onto a log scale. This paper surveys many of the commonly used invariance methods, and asse...

Invariant subsets under compact quantum group actions

OpenAIRE

Huang, Huichi

2012-01-01

We investigate compact quantum group actions on unital $C^*$-algebras by analyzing invariant subsets and invariant states. In particular, we come up with the concept of compact quantum group orbits and use it to show that countable compact metrizable spaces with infinitely many points are not quantum homogeneous spaces.

Borromean surgery formula for the Casson invariant

DEFF Research Database (Denmark)

Meilhan, Jean-Baptiste Odet Thierry

2008-01-01

It is known that every oriented integral homology 3-sphere can be obtained from S3 by a finite sequence of Borromean surgeries. We give an explicit formula for the variation of the Casson invariant under such a surgery move. The formula involves simple classical invariants, namely the framing...

Adsorption of Sr(II) and Eu(III) on Na-rectorite. Effect of pH, ionic strength, concentration and modelling

Energy Technology Data Exchange (ETDEWEB)

Hu, J.; Wang, X.K. [School of Nuclear Science and Engineering, North China Electric Power Univ., BJ (China); Key Lab. of Novel Thin Film Solar Cells, Inst. of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Chen, C.L.; Sheng, G.D.; Li, J.X. [Key Lab. of Novel Thin Film Solar Cells, Inst. of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Chen, Y.X. [School of Nuclear Science and Engineering, North China Electric Power Univ., BJ (China)

2010-07-01

The surface charge characteristics of Na-rectorite (NaAl{sub 4}[Si,Al]{sub 8}O{sub 20}(OH){sub 4}.nH{sub 2}O;) were studied by potentiometric acid-base titrations. Sr(II) and Eu(III) adsorptions on Na-rectorite as a function of pH, ionic strength, and Sr(II)/Eu(III) concentrations were carried out to investigate the surface interactions between Sr(II)/Eu(III) with Na-rectorite. The results indicated that the adsorptions of Sr(II) and Eu(III) on Na-rectorite increased with increasing pH and decreased with increasing ionic strength and initial Sr(II)/Eu(III) concentrations, and that the affinity of Na-rectorite for Eu(III) was much higher than for Sr(II). The experimental data of Sr(II)/Eu(III) adsorption were simulated by the diffuse-layer model (DLM) well with the aid of FITEQL 3.2. Simultaneous adsorptions of Sr(II) and Eu(III) on Na-rectorite were also modeled using the DLM. The adsorption mechanisms of Sr(II) and Eu(III) on Na-rectorite may be dominated by ion exchange interaction at low pH or moderate pH, and by surface complexation interaction at high pH. (orig.)

Conformal (WEYL) invariance and Higgs mechanism

International Nuclear Information System (INIS)

Zhao Shucheng.

1991-10-01

A massive Yang-Mills field theory with conformal invariance and gauge invariance is proposed. It involves gravitational and various gauge interactions, in which all the mass terms appear as a uniform form of interaction m(x) KΦ(x). When the conformal symmetry is broken spontaneously and gravitation is ignored, the Higgs field emerges naturally, where the imaginary mass μ can be described as a background curvature. (author). 7 refs

Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?

Science.gov (United States)

Haeryfar, S M Mansour; Shaler, Christopher R; Rudak, Patrick T

2018-02-22

Mucosa-associated invariant T (MAIT) cells are a subset of innate-like T lymphocytes known for their ability to respond to MHC-related protein 1 (MR1)-restricted stimuli and select cytokine signals. They are abundant in humans and especially enriched in mucosal layers, common sites of neoplastic transformation. MAIT cells have been found within primary and metastatic tumors. However, whether they promote malignancy or contribute to anticancer immunity is unclear. On the one hand, MAIT cells produce IL-17A in certain locations and under certain circumstances, which could in turn facilitate neoangiogenesis, intratumoral accumulation of immunosuppressive cell populations, and cancer progression. On the other hand, they can express a potent arsenal of cytotoxic effector molecules, NKG2D and IFN-γ, all of which have established roles in cancer immune surveillance. In this review, we highlight MAIT cells' characteristics as they might pertain to cancer initiation, progression, or control. We discuss recent findings, including our own, that link MAIT cells to cancer, with a focus on colorectal carcinoma, as well as some of the outstanding questions in this active area of research. Finally, we provide a hypothetical picture in which MAIT cells constitute attractive targets in cancer immunotherapy.

HLA Class II Alleles Susceptibility Markers of Type 1 Diabetes Fail to Specify Phenotypes of Ketosis-Prone Diabetes in Adult Tunisian Patients

Directory of Open Access Journals (Sweden)

Lilia Laadhar

2011-01-01

Full Text Available We aimed to characterize the different subgroups of ketosis-prone diabetes (KPD in a sample of Tunisian patients using the Aβ scheme based on the presence or absence of β-cell autoantibodies (A+ or A− and β-cell functional reserve (β+ or β− and we investigated whether HLA class II alleles could contribute to distinct KPD phenotypes. We enrolled 43 adult patients with a first episode of ketosis. For all patients we evaluated clinical parameters, β-cell autoimmunity, β-cell function and HLA class II alleles. Frequency distribution of the 4 subgroups was 23.3% A+β−, 23.3% A−β−, 11.6% A+β+ and 41.9% A−β+. Patients from the group A+β− were significantly younger than those from the group A−β− (P=.002. HLA susceptibility markers were significantly more frequent in patients with autoantibodies (P=.003. These patients also had resistance alleles but they were more frequent in A+β+ than A+β− patients (P=.04. Insulin requirement was not associated to the presence or the absence of HLA susceptibility markers. HLA class II alleles associated with susceptibility to autoimmune diabetes have not allowed us to further define Tunisian KPD groups. However, high prevalence of HLA resistance alleles in our patients may reflect a particular genetic background of Tunisian KPD population.

Topological excitations in U(1) -invariant theories

International Nuclear Information System (INIS)

Savit, R.

1977-01-01

A class of U(1) -invariant theories in d dimensions is introduced on a lattice. These theories are labeled by a simplex number s, with 1 < or = s < d. The case with s = 1 is the X-Y model; and s = 2 gives compact photodynamics. An exact duality transformation is applied to show that the U(1) -invariant theory in d dimensions with simplex number s is the same as a similar theory in d dimensions but which is Z /sub infinity/-invariant and has simplex number s = d-s. This dual theory describes the topological excitations of the original theory. These excitations are of dimension s - 1

A case control association study of ACE gene polymorphism (I/D) with hypertension in Punjabi population from Faisalabad, Pakistan.

Science.gov (United States)

Hussain, Misbah; Awan, Fazli Rabbi; Gujjar, Amna; Hafeez, Shakir; Islam, Mehboob

2018-01-01

Angiotensin converting enzyme (ACE) is a key component of renin angiotensin aldosterone system. It converts angiotensin I to angiotensin II. Insertion/deletion (I/D) polymorphism of ACE gene is found associated with several complications. However, its association with hypertension and related metabolic diseases is still controversial. So, the aim of the present study was to check this association for Punjabi population from Faisalabad, Pakistan. For this purpose, blood samples (patients = 100, controls = 48) were collected and several biochemical parameters were measured. Genotyping for ACE (I/D) polymorphism was performed by polymerase chain reaction (PCR) assay. ID genotype is found prevalent in the studied population as 41% in control subjects and 61% in patients. Furthermore, chi-square analysis showed significant (p = 0.005) difference for genotypic frequencies between both groups. One-way ANOVA for association of II, ID, and DD genotypes with anthropometric, clinical, and biochemical parameters showed that in patient group, DD genotype is significantly (p = 0.041) associated with systolic blood pressure (SBP). Moreover, ID genotype is found associated with the presence of cardiovascular diseases. This study concludes that DD genotype is strongly associated with higher SBP in hypertensive patients.

Exposure of a distinct PDCA-1+ (CD317 B cell population to agonistic anti-4-1BB (CD137 inhibits T and B cell responses both in vitro and in vivo.

Directory of Open Access Journals (Sweden)

Dass S Vinay

Full Text Available 4-1BB (CD137 is an important T cell activating molecule. Here we report that it also promotes development of a distinct B cell subpopulation co-expressing PDCA-1. 4-1BB is expressed constitutively, and its expression is increased when PDCA-1(+ B cells are activated. We found that despite a high level of surface expression of 4-1BB on PDCA-1(+ B cells, treatment of these cells with agonistic anti-4-1BB mAb stimulated the expression of only a few activation markers (B7-2, MHC II, PD-L2, cytokines (IL-12p40/p70, and chemokines (MCP-1, RANTES, as well as sTNFR1, and the immunosuppressive enzyme, IDO. Although the PDCA-1(+ B cells stimulated by anti-4-1BB expressed MHC II at high levels and took up antigens efficiently, Ig class switching was inhibited when they were pulsed with T-independent (TI or T-dependent (TD Ags and adoptively transferred into syngeneic recipients. Furthermore, when anti-4-1BB-treated PDCA-1(+ B cells were pulsed with OVA peptide and combined with Vα2(+CD4(+ T cells, Ag-specific cell division was inhibited both in vitro and in vivo. Our findings suggest that the 4-1BB signal transforms PDCA-1(+ B cells into propagators of negative immune regulation, and establish an important role for 4-1BB in PDCA-1(+ B cell development and function.

Invariance group of the Finster metric function

International Nuclear Information System (INIS)

Asanov, G.S.

1985-01-01

An invariance group of the Finsler metric function is introduced and studied that directly generalized the respective concept (a group of Euclidean rolations) of the Rieman geometry. A sequential description of the isotopic invariance of physical fields on the base of the Finsler geometry is possible in terms of this group

Childhood Trauma Questionnaire: factor structure, measurement invariance, and validity across emotional disorders

NARCIS (Netherlands)

Spinhoven, P.; Penninx, B.W.; Hickendorff, M.; van Hemert, A.M.; Bernstein, D.P.; Elzinga, B.M.

2014-01-01

To study the psychometric properties of the Childhood Trauma Questionnaire-Short Form (CTQ-SF), we determined its dimensional structure, measurement invariance across presence of emotional disorders, the association of the CTQ-SF with an analogous interview-based measure (CTI) across presence of

Translation invariance, commutation relations and ultraviolet/infrared mixing

International Nuclear Information System (INIS)

Galluccio, Salvatore; Lizzi, Fedele; Vitale, Patrizia

2009-01-01

We show that the Ultraviolet/Infrared mixing of noncommutative field theories with the Groenewold-Moyal product, whereby some (but not all) ultraviolet divergences become infrared, is a generic feature of translationally invariant associative products. We find, with an explicit calculation that the phase appearing in the nonplanar diagrams is the one given by the commutator of the coordinates, the semiclassical Poisson structure of the non commutative spacetime. We do this with an explicit calculation for represented generic products.

Note on Weyl versus conformal invariance in field theory

Energy Technology Data Exchange (ETDEWEB)

Wu, Feng [Nanchang University, Department of Physics, Nanchang (China)

2017-12-15

It was argued recently that conformal invariance in flat spacetime implies Weyl invariance in a general curved background for unitary theories and possible anomalies in the Weyl variation of scalar operators are identified. We argue that generically unitarity alone is not sufficient for a conformal field theory to be Weyl invariant. Furthermore, we show explicitly that when a unitary conformal field theory couples to gravity in a Weyl-invariant way, each primary scalar operator that is either relevant or marginal in the unitary conformal field theory corresponds to a Weyl-covariant operator in the curved background. (orig.)