[Protective activity of S-PT84, a heat-killed preparation of Lactobacillus pentosus, against oral and gastric candidiasis in an experimental murine model].

Science.gov (United States)

Hayama, Kazumi; Ishijima, Sanae; Ono, Yoshiko; Izumo, Takayuki; Ida, Masayuki; Shibata, Hiroshi; Abe, Shigeru

2014-01-01

The effect of S-PT84, a heat-killed preparation of Lactobacillus pentosus on growth of Candida albicans was examined in vitro and in vivo. The mycelial growth was effectively inhibited by S-PT84 and seemed to bind to the hyphae. We assessed the potential of S-PT84 for treatment of oral and gastric candidiasis using a murine model. When 2 mg of S-PT84 was administered three times into the oral cavity of orally Candida infected mice, the score of lesions on the tongue was improved on day 2. When 50 μl and 200 μl of S-PT84 (10 mg/ml) were administered three times into the oral cavity (0.5 mg × 3) and the stomach (2 mg × 3) of the same mouse model, the number of viable Candida cells in the stomach was reduced significantly on day 2. These findings suggest the possibility that S-PT84 has potential as a food ingredient supporting anti-Candida treatment, especially for Candida infection in the gastrointestinal tract.

SPT0346-52: NEGLIGIBLE AGN ACTIVITY IN A COMPACT, HYPER-STARBURST GALAXY AT z = 5.7

Energy Technology Data Exchange (ETDEWEB)

Ma, Jingzhe; Gonzalez, Anthony H. [Department of Astronomy, University of Florida, Gainesville, FL 32611 (United States); Vieira, J. D.; Sreevani, J. [Department of Astronomy and Department of Physics, University of Illinois, 1002 West Green St., Urbana, IL 61801 (United States); Aravena, M. [Núcleo de Astronomía, Facultad de Ingeniería, Universidad Diego Portales, Av. Ejército 441, Santiago (Chile); Ashby, M. L. N. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Béthermin, M.; Breuck, C. de; Gullberg, B. [European Southern Observatory, Karl Schwarzschild Straße 2, D-85748 Garching (Germany); Bothwell, M. S. [Cavendish Laboratory, University of Cambridge, JJ Thompson Ave, Cambridge CB3 0HA (United Kingdom); Brandt, W. N. [Institute for Gravitation and the Cosmos, The Pennsylvania State University, University Park, PA 16802 (United States); Carlstrom, J. E. [Kavli Institute for Cosmological Physics, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Chapman, S. C. [Dalhousie University, Halifax, Nova Scotia (Canada); Hezaveh, Y. [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Stanford, CA 94305 (United States); Litke, K.; Marrone, D. P.; Spilker, J. S. [Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States); Malkan, M. [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1547 (United States); McDonald, M. [Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, 37-582C, Cambridge, MA 02139 (United States); Murphy, E. J., E-mail: jingzhema@ufl.edu [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); and others

2016-12-01

We present Chandra ACIS-S and Australia Telescope Compact Array (ATCA) radio continuum observations of the strongly lensed dusty, star-forming galaxy SPT-S J034640-5204.9 (hereafter SPT0346-52) at z = 5.656. This galaxy has also been observed with ALMA, HST , Spitzer , Herschel , Atacama Pathfinder EXperiment, and the Very Large Telescope. Previous observations indicate that if the infrared (IR) emission is driven by star formation, then the inferred lensing-corrected star formation rate (SFR) (∼4500 M {sub ☉} yr{sup −1}) and SFR surface density Σ{sub SFR} (∼2000 M {sub ☉} yr{sup −1} kpc{sup −2}) are both exceptionally high. It remained unclear from the previous data, however, whether a central active galactic nucleus (AGN) contributes appreciably to the IR luminosity. The Chandra upper limit shows that SPT0346-52 is consistent with being star formation dominated in the X-ray, and any AGN contribution to the IR emission is negligible. The ATCA radio continuum upper limits are also consistent with the FIR-to-radio correlation for star-forming galaxies with no indication of an additional AGN contribution. The observed prodigious intrinsic IR luminosity of (3.6 ± 0.3) × 10{sup 13} L {sub ☉} originates almost solely from vigorous star formation activity. With an intrinsic source size of 0.61 ± 0.03 kpc, SPT0346-52 is confirmed to have one of the highest Σ{sub SFR} of any known galaxy. This high Σ{sub SFR}, which approaches the Eddington limit for a radiation pressure supported starburst, may be explained by a combination of very high star formation efficiency and gas fraction.

SPT0346-52: NEGLIGIBLE AGN ACTIVITY IN A COMPACT, HYPER-STARBURST GALAXY AT z = 5.7

International Nuclear Information System (INIS)

Ma, Jingzhe; Gonzalez, Anthony H.; Vieira, J. D.; Sreevani, J.; Aravena, M.; Ashby, M. L. N.; Béthermin, M.; Breuck, C. de; Gullberg, B.; Bothwell, M. S.; Brandt, W. N.; Carlstrom, J. E.; Chapman, S. C.; Hezaveh, Y.; Litke, K.; Marrone, D. P.; Spilker, J. S.; Malkan, M.; McDonald, M.; Murphy, E. J.

2016-01-01

We present Chandra ACIS-S and Australia Telescope Compact Array (ATCA) radio continuum observations of the strongly lensed dusty, star-forming galaxy SPT-S J034640-5204.9 (hereafter SPT0346-52) at z = 5.656. This galaxy has also been observed with ALMA, HST , Spitzer , Herschel , Atacama Pathfinder EXperiment, and the Very Large Telescope. Previous observations indicate that if the infrared (IR) emission is driven by star formation, then the inferred lensing-corrected star formation rate (SFR) (∼4500 M ☉ yr −1 ) and SFR surface density Σ SFR (∼2000 M ☉ yr −1 kpc −2 ) are both exceptionally high. It remained unclear from the previous data, however, whether a central active galactic nucleus (AGN) contributes appreciably to the IR luminosity. The Chandra upper limit shows that SPT0346-52 is consistent with being star formation dominated in the X-ray, and any AGN contribution to the IR emission is negligible. The ATCA radio continuum upper limits are also consistent with the FIR-to-radio correlation for star-forming galaxies with no indication of an additional AGN contribution. The observed prodigious intrinsic IR luminosity of (3.6 ± 0.3) × 10 13 L ☉ originates almost solely from vigorous star formation activity. With an intrinsic source size of 0.61 ± 0.03 kpc, SPT0346-52 is confirmed to have one of the highest Σ SFR of any known galaxy. This high Σ SFR , which approaches the Eddington limit for a radiation pressure supported starburst, may be explained by a combination of very high star formation efficiency and gas fraction.

Integrated performance of a frequency domain multiplexing readout in the SPT-3G receiver

Science.gov (United States)

Bender, A. N.; Ade, P. A. R.; Anderson, A. J.; Avva, J.; Ahmed, Z.; Arnold, K.; Austermann, J. E.; Basu Thakur, R.; Benson, B. A.; Bleem, L. E.; Byrum, K.; Carlstrom, J. E.; Carter, F. W.; Chang, C. L.; Cho, H. M.; Cliche, J. F.; Crawford, T. M.; Cukierman, A.; Czaplewski, D. A.; Ding, J.; Divan, R.; de Haan, T.; Dobbs, M. A.; Dutcher, D.; Everett, W.; Gilbert, A.; Groh, J. C.; Guyser, R.; Halverson, N. W.; Harke-Hosemann, A.; Harrington, N. L.; Hattori, K.; Henning, J. W.; Hilton, G. C.; Holzapfel, W. L.; Huang, N.; Irwin, K. D.; Jeong, O.; Khaire, T.; Korman, M.; Kubik, D.; Kuo, C. L.; Lee, A. T.; Leitch, E. M.; Lendinez, S.; Meyer, S. S.; Miller, C. S.; Montgomery, J.; Nadolski, A.; Natoli, T.; Nguyen, H.; Novosad, V.; Padin, S.; Pan, Z.; Pearson, J.; Posada, C. M.; Rahlin, A.; Reichardt, C. L.; Ruhl, J. E.; Saliwanchik, B. R.; Sayre, J. T.; Shariff, J. A.; Shirley, Ian; Shirokoff, E.; Smecher, G.; Sobrin, J.; Stan, L.; Stark, A. A.; Story, K.; Suzuki, A.; Tang, Q. Y.; Thompson, K. L.; Tucker, C.; Vanderlinde, K.; Vieira, J. D.; Wang, G.; Whitehorn, N.; Yefremenko, V.; Yoon, K. W.

2016-07-01

The third generation receiver for the South Pole Telescope, SPT-3G, will make extremely deep, arcminuteresolution maps of the temperature and polarization of the cosmic microwave background. The SPT-3G maps will enable studies of the B-mode polarization signature, constraining primordial gravitational waves as well as the effect of massive neutrinos on structure formation in the late universe. The SPT-3G receiver will achieve exceptional sensitivity through a focal plane of 16,000 transition-edge sensor bolometers, an order of magnitude more than the current SPTpol receiver. SPT-3G uses a frequency domain multiplexing (fMux) scheme to read out the focal plane, combining the signals from 64 bolometers onto a single pair of wires. The fMux readout facilitates the large number of detectors in the SPT-3G focal plane by limiting the thermal load due to readout wiring on the 250 millikelvin cryogenic stage. A second advantage of the fMux system is that the operation of each bolometer can be optimized. In addition to these benefits, the fMux readout introduces new challenges into the design and operation of the receiver. The bolometers are operated at a range of frequencies up to 5 MHz, requiring control of stray reactances over a large bandwidth. Additionally, crosstalk between multiplexed detectors will inject large false signals into the data if not adequately mitigated. SPT-3G is scheduled to deploy to the South Pole Telescope in late 2016. Here, we present the pre-deployment performance of the fMux readout system with the SPT-3G focal plane.

Mengapa Perlu Menghapus SPT Tahunan 1721?

Directory of Open Access Journals (Sweden)

Yenni Mangoting

2008-01-01

Full Text Available Employers as a withholders calculate employment income tax with two ways, there are 1 calculate employment income tax in the case of periodical tax return and 2 re-count for employment income tax and combine all the income that incurred in tax year and report them in to annual income tax return form 1721. Under payment of tax liability must be paid at the latest on the 25th day of the third month after a fiscal year ended. Because of that employers actually not calculate employment income tax base on real income. This system actually make difficulties and in addition withholders have an opportunity by rule for re-count employment income tax as base for fill up annual income tax return form 1721- A1 or 1721 A2 . Employment income tax calculation in year ended was final result. Abstract in Bahasa Indonesia: Pemberi kerja yang dalam hal ini bertindak sebagai pemotong pajak, menghitung PPh pasal 21 dalam dua tahap, yaitu 1 menghitung PPh pasal 21 masa yang dilaporkan dan disetorkan setiap bulan dan 2 Perhitungan ulang PPh Pasal 21 dengan menjumlahkan semua penghasilan yang diterima dalam satu tahun pajak dan dilaporkan dalam SPT Tahunan dengan form 1721. Kekurangan pembayaran harus dilunasi sebelum tanggal 25 Maret tahun pajak berikutnya. Oleh karena itu pemberi kerja biasanya tidak mengitung PPh pasal 21 masa berdasarkan penghasilan yang sebenarnya. Selain karena secara administrasi merepotkan, pemberi kerja juga di beri kesempatan menghitung kembali PPh Pasal 21 sebagai dasar pengisian Form 1721 - A1 atau 1721 A2. Penghitungan kembali PPh Pasal 21 pada akhir tahun menjadi perhitungan final hasil revisi perhitungan PPh 21 masa. Kata kunci: pemberi kerja, SPT Tahunan PPh Pasal 21, SPT Masa PPh Pasal 21, Wajib Pajak

Large arrays of dual-polarized multichroic TES detectors for CMB measurements with the SPT-3G receiver

Science.gov (United States)

Posada, Chrystian M.; Ade, Peter A. R.; Anderson, Adam J.; Avva, Jessica; Ahmed, Zeeshan; Arnold, Kam S.; Austermann, Jason; Bender, Amy N.; Benson, Bradford A.; Bleem, Lindsey; Byrum, Karen; Carlstrom, John E.; Carter, Faustin W.; Chang, Clarence; Cho, Hsiao-Mei; Cukierman, Ari; Czaplewski, David A.; Ding, Junjia; Divan, Ralu N. S.; de Haan, Tijmen; Dobbs, Matt; Dutcher, Daniel; Everett, Wenderline; Gannon, Renae N.; Guyser, Robert J.; Halverson, Nils W.; Harrington, Nicholas L.; Hattori, Kaori; Henning, Jason W.; Hilton, Gene C.; Holzapfel, William L.; Huang, Nicholas; Irwin, Kent D.; Jeong, Oliver; Khaire, Trupti; Korman, Milo; Kubik, Donna L.; Kuo, Chao-Lin; Lee, Adrian T.; Leitch, Erik M.; Lendinez Escudero, Sergi; Meyer, Stephan S.; Miller, Christina S.; Montgomery, Joshua; Nadolski, Andrew; Natoli, Tyler J.; Nguyen, Hogan; Novosad, Valentyn; Padin, Stephen; Pan, Zhaodi; Pearson, John E.; Rahlin, Alexandra; Reichardt, Christian L.; Ruhl, John E.; Saliwanchik, Benjamin; Shirley, Ian; Sayre, James T.; Shariff, Jamil A.; Shirokoff, Erik D.; Stan, Liliana; Stark, Antony A.; Sobrin, Joshua; Story, Kyle; Suzuki, Aritoki; Tang, Qing Yang; Thakur, Ritoban B.; Thompson, Keith L.; Tucker, Carole E.; Vanderlinde, Keith; Vieira, Joaquin D.; Wang, Gensheng; Whitehorn, Nathan; Yefremenko, Volodymyr; Yoon, Ki Won

2016-07-01

Detectors for cosmic microwave background (CMB) experiments are now essentially background limited, so a straightforward alternative to improve sensitivity is to increase the number of detectors. Large arrays of multichroic pixels constitute an economical approach to increasing the number of detectors within a given focal plane area. Here, we present the fabrication of large arrays of dual-polarized multichroic transition-edge-sensor (TES) bolometers for the South Pole Telescope third-generation CMB receiver (SPT-3G). The complete SPT-3G receiver will have 2690 pixels, each with six detectors, allowing for individual measurement of three spectral bands (centered at 95 GHz, 150 GHz and 220 GHz) in two orthogonal polarizations. In total, the SPT-3G focal plane will have 16140 detectors. Each pixel is comprised of a broad-band sinuous antenna coupled to a niobium microstrip transmission line. In-line filters are used to define the different band-passes before the millimeter-wavelength signal is fed to the respective Ti/Au TES sensors. Detectors are read out using a 64x frequency domain multiplexing (fMux) scheme. The microfabrication of the SPT-3G detector arrays involves a total of 18 processes, including 13 lithography steps. Together with the fabrication process, the effect of processing on the Ti/Au TES's Tc is discussed. In addition, detectors fabricated with Ti/Au TES films with Tc between 400 mK 560 mK are presented and their thermal characteristics are evaluated. Optical characterization of the arrays is presented as well, indicating that the response of the detectors is in good agreement with the design values for all three spectral bands (95 GHz, 150 GHz, and 220 GHz). The measured optical efficiency of the detectors is between 0.3 and 0.8. Results discussed here are extracted from a batch of research of development wafers used to develop the baseline process for the fabrication of the arrays of detectors to be deployed with the SPT-3G receiver. Results from

Cross-correlation of gravitational lensing from DES Science Verification data with SPT and Planck lensing

Energy Technology Data Exchange (ETDEWEB)

Kirk, D.; Omori, Y.; Benoit-Lévy, A.; Cawthon, R.; Chang, C.; Larsen, P.; Amara, A.; Bacon, D.; Crawford, T. M.; Dodelson, S.; Fosalba, P.; Giannantonio, T.; Holder, G.; Jain, B.; Kacprzak, T.; Lahav, O.; MacCrann, N.; Nicola, A.; Refregier, A.; Sheldon, E.; Story, K. T.; Troxel, M. A.; Vieira, J. D.; Vikram, V.; Zuntz, J.; Abbott, T. M. C.; Abdalla, F. B.; Becker, M. R.; Benson, B. A.; Bernstein, G. M.; Bernstein, R. A.; Bleem, L. E.; Bonnett, C.; Bridle, S. L.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Capozzi, D.; Carlstrom, J. E.; Rosell, A. Carnero; Kind, M. Carrasco; Carretero, J.; Crocce, M.; Cunha, C. E.; D' Andrea, C. B.; da Costa, L. N.; Desai, S.; Diehl, H. T.; Dietrich, J. P.; Doel, P.; Eifler, T. F.; Evrard, A. E.; Flaugher, B.; Frieman, J.; Gerdes, D. W.; Goldstein, D. A.; Gruen, D.; Gruendl, R. A.; Honscheid, K.; James, D. J.; Jarvis, M.; Kent, S.; Kuehn, K.; Kuropatkin, N.; Lima, M.; March, M.; Martini, P.; Melchior, P.; Miller, C. J.; Miquel, R.; Nichol, R. C.; Ogando, R.; Plazas, A. A.; Reichardt, C. L.; Roodman, A.; Rozo, E.; Rykoff, E. S.; Sako, M.; Sanchez, E.; Scarpine, V.; Schubnell, M.; Sevilla-Noarbe, I.; Simard, G.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Wechsler, R. H.; Weller, J.

2016-03-10

We measure the cross-correlation between weak lensing of galaxy images and of the cosmic microwave background (CMB). The effects of gravitational lensing on different sources will be correlated if the lensing is caused by the same mass fluctuations. We use galaxy shape measurements from 139 deg$^{2}$ of the Dark Energy Survey (DES) Science Verification data and overlapping CMB lensing from the South Pole Telescope (SPT) and Planck. The DES source galaxies have a median redshift of $z_{\\rm med} {\\sim} 0.7$, while the CMB lensing kernel is broad and peaks at $z{\\sim}2$. The resulting cross-correlation is maximally sensitive to mass fluctuations at $z{\\sim}0.44$. Assuming the Planck 2015 best-fit cosmology, the amplitude of the DES$\\times$SPT cross-power is found to be $A = 0.88 \\pm 0.30$ and that from DES$\\times$Planck to be $A = 0.86 \\pm 0.39$, where $A=1$ corresponds to the theoretical prediction. These are consistent with the expected signal and correspond to significances of $2.9 \\sigma$ and $2.2 \\sigma$ respectively. We demonstrate that our results are robust to a number of important systematic effects including the shear measurement method, estimator choice, photometric redshift uncertainty and CMB lensing systematics. Significant intrinsic alignment of galaxy shapes would increase the cross-correlation signal inferred from the data; we calculate a value of $A = 1.08 \\pm 0.36$ for DES$\\times$SPT when we correct the observations with a simple IA model. With three measurements of this cross-correlation now existing in the literature, there is not yet reliable evidence for any deviation from the expected LCDM level of cross-correlation, given the size of the statistical uncertainties and the significant impact of systematic errors, particularly IAs. We provide forecasts for the expected signal-to-noise of the combination of the five-year DES survey and SPT-3G.

CSIR Annual report 1967

CSIR Research Space (South Africa)

CSIR

1967-01-01

Full Text Available This report presents the twenty third annual report of the Council for Scientific and Industrial Research. The report covers the period from the 1st January, 1967, to the 31st December 1967. Balance sheets and statements of income and expenditure...

PERANCANGAN DAN PEMBUATAN SISTEM INFORMASI PENGGAJIAN DAN LAPORAN SPT TAHUNAN UNTUK KARYAWAN DI PERUSAHAAN KONVEKSI CV. X

Directory of Open Access Journals (Sweden)

Yulia Yulia

2009-01-01

Full Text Available CV. X is a garment company which has 55 employees. Every end of the month the company doing payroll calculations and every year make an annual tax report (Notice Letter / SPT. Currently the calculation of salaries and the making of SPT are still done manually and thus require a long time and the large possibility of miscalculation. In this research, we have designed a payroll information system and SPT reporting, including employee attendance system, payroll calculation system and the various attribute such as overtime, furlough, deductions and so forth automatically. This system is able to do the calculation and reporting of annual tax returns and tax correction automatically. Besides, the system is also able to create various reports such as salary statements, tax cuts statements, the report to the director of such employee data report, employee history report, and payroll report. From the test results of payroll information systems and SPT report, can be seen that the system is able to perform the calculation of salaries and annual tax returns correctly. Abstract in Bahasa Indonesia: CV. X merupakan sebuah perusahaan koveksi dengan total karyawan sekitar 55 orang. Setiap akhir bulan perusahaan melakukan penghitungan gaji karyawan dan tiap tahun melakukan pembuatan laporan pajak tahunan (Surat Pemberitahuan/SPT. Saat ini penghitungan gaji dan pembuatan SPT ini masih dilakukan secara manual sehingga membutuhkan waktu yang lama serta besar kemungkinan terjadinya kesalahan perhitungan. Pada penelitian ini, dirancang sebuah sistem informasi penggajian dan pembuatan laporan SPT, antara lain meliputi sistem absensi karyawan, sistem penghitungan gaji dan berbagai attributnya seperti lembur, cuti, potongan dan sebagainya secara terotomatisasi. Sistem ini juga mampu melakukan penghitungan dan pembuatan laporan SPT tahunan serta koreksi pajak secara terotomatisasi. Selain itu sistem juga mampu membuat berbagai laporan baik yang ditujukan untuk karyawan

Evaluation of SPT energy for Donut and Safety hammers using CPT measurements in Egypt

Directory of Open Access Journals (Sweden)

Rami M. El-Sherbiny

2013-12-01

Full Text Available Standard Penetration Test (SPT blow counts require correction prior to utilization in soil characterization and determination of properties and behavior. Among the most important corrections is the energy correction required to adjust the blow counts to 60% energy efficiency. However, there are no published data supporting commonly used value in Egypt. This paper presents an evaluation of the energy efficiency of the Donut and Safety hammers commonly used in Egypt and the associated energy correction factor. The energy efficiency is estimated by comparing N-values from the SPT to back-calculated N60 values from the Cone Penetration Test (CPT using well established correlations. Results indicate that the energy efficiency of the Donut hammer based on current practice in Egypt is approximately 50%. Thus, the back-calculated energy correction factor is approximately 0.82. For the Safety hammer, results indicate that the energy efficiency is approximately 60%, and the energy correction factor is approximately 1.0.

Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5.

Science.gov (United States)

Blythe, Amanda; Gunasekara, Sanjika; Walshe, James; Mackay, Joel P; Hartzog, Grant A; Vrielink, Alice

2014-08-01

Spt4/5 is a hetero-dimeric transcription elongation factor that can both inhibit and promote transcription elongation by RNA polymerase II (RNAPII). However, Spt4/5's mechanism of action remains elusive. Spt5 is an essential protein and the only universally-conserved RNAP-associated transcription elongation factor. The protein contains multiple Kyrpides, Ouzounis and Woese (KOW) domains. These domains, in other proteins, are thought to bind RNA although there is little direct evidence in the literature to support such a function in Spt5. This could be due, at least in part, to difficulties in expressing and purifying recombinant Spt5. When expressed in Escherichia coli (E. coli), Spt5 is innately insoluble. Here we report a new approach for the successful expression and purification of milligram quantities of three different multi-KOW domain complexes of Saccharomyces cerevisiae Spt4/5 for use in future functional studies. Using the E. coli strain Rosetta2 (DE3) we have developed strategies for co-expression of Spt4 and multi-KOW domain Spt5 complexes from the bi-cistronic pET-Duet vector. In a second strategy, Spt4/5 was expressed via co-transformation of Spt4 in the vector pET-M11 with Spt5 ubiquitin fusion constructs in the vector pHUE. We characterized the multi-KOW domain Spt4/5 complexes by Western blot, limited proteolysis, circular dichroism, SDS-PAGE and size exclusion chromatography-multiangle light scattering and found that the proteins are folded with a Spt4:Spt5 hetero-dimeric stoichiometry of 1:1. These expression constructs encompass a larger region of Spt5 than has previously been reported, and will provide the opportunity to elucidate the biological function of the multi-KOW containing Spt5. Copyright © 2014 Elsevier Inc. All rights reserved.

El maltrato de género en «Te doy mis ojos» (2003

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Rosendo BUGARÍN GONZÁLEZ

2016-04-01

Full Text Available En nuestro país son escasas y de muy reciente aparición las películas que tratan sobre la violencia de género desde una óptica de rechazo y denuncia. Probablemente la más representativa sea Te doy mis ojos. Su visionado pretende contribuir a concienciar y a hacer reflexionar al espectador sobre la grave dad de esta lacra en nuestra sociedad. No cabe duda de que para llevar a cabo este proyecto, sus respon sables tuvieron que emprender una muy seria y rigurosa labor de investigación. En efecto, este film es un auténtico manual (o incluso tratado sobre maltrato de género. En él se recoge prácticamente “todo” lo relacionado con este problema de salud: el círculo de la violencia, el plan de huída, las consultas sanitarias que no detectaron el problema, el sufrimiento de la víctima, su necesidad de apoyo y acompañamiento así como el contexto del maltratador.

Performance Evaluation of the SPT-140

Science.gov (United States)

Manzella, David; Sarmiento, Charles; Sankovic, John; Haag, Tom

1997-01-01

As part of an on-going cooperative program with industry, an engineering model SPT-140 Hall thruster, which may be suitable for orbit insertion and station-keeping of geosynchronous communication satellites, was evaluated with respect to thrust and radiated electromagnetic interference at the NASA Lewis Research Center. Performance measurements were made using a laboratory model propellant feed system and commercial power supplies. The engine was operated in a space simulation chamber capable of providing background pressures of 4 x 10(exp -6) Torr or less during thruster operation. Thrust was measured at input powers ranging from 1.5 to 5 kilowatts with two different output filter configurations. The broadband electromagnetic emission spectra generated by the engine was also measured for a range of frequencies from 0.01 to 18,000 Mhz. These results are compared to the noise threshold of the measurement system and MIL-STD-461C where appropriate.

MASS CALIBRATION AND COSMOLOGICAL ANALYSIS OF THE SPT-SZ GALAXY CLUSTER SAMPLE USING VELOCITY DISPERSION σ v AND X-RAY Y X MEASUREMENTS

International Nuclear Information System (INIS)

Bocquet, S.; Saro, A.; Mohr, J. J.; Bazin, G.; Chiu, I.; Desai, S.; Aird, K. A.; Ashby, M. L. N.; Bayliss, M.; Bautz, M.; Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Crawford, T. M.; Crites, A. T.; Brodwin, M.; Cho, H. M.; Clocchiatti, A.; De Haan, T.

2015-01-01

We present a velocity-dispersion-based mass calibration of the South Pole Telescope Sunyaev-Zel'dovich effect survey (SPT-SZ) galaxy cluster sample. Using a homogeneously selected sample of 100 cluster candidates from 720 deg 2 of the survey along with 63 velocity dispersion (σ v ) and 16 X-ray Y X measurements of sample clusters, we simultaneously calibrate the mass-observable relation and constrain cosmological parameters. Our method accounts for cluster selection, cosmological sensitivity, and uncertainties in the mass calibrators. The calibrations using σ v and Y X are consistent at the 0.6σ level, with the σ v calibration preferring ∼16% higher masses. We use the full SPT CL data set (SZ clusters+σ v +Y X ) to measure σ 8 (Ω m /0.27) 0.3 = 0.809 ± 0.036 within a flat ΛCDM model. The SPT cluster abundance is lower than preferred by either the WMAP9 or Planck+WMAP9 polarization (WP) data, but assuming that the sum of the neutrino masses is ∑m ν = 0.06 eV, we find the data sets to be consistent at the 1.0σ level for WMAP9 and 1.5σ for Planck+WP. Allowing for larger ∑m ν further reconciles the results. When we combine the SPT CL and Planck+WP data sets with information from baryon acoustic oscillations and Type Ia supernovae, the preferred cluster masses are 1.9σ higher than the Y X calibration and 0.8σ higher than the σ v calibration. Given the scale of these shifts (∼44% and ∼23% in mass, respectively), we execute a goodness-of-fit test; it reveals no tension, indicating that the best-fit model provides an adequate description of the data. Using the multi-probe data set, we measure Ω m = 0.299 ± 0.009 and σ 8 = 0.829 ± 0.011. Within a νCDM model we find ∑m ν = 0.148 ± 0.081 eV. We present a consistency test of the cosmic growth rate using SPT clusters. Allowing both the growth index γ and the dark energy equation-of-state parameter w to vary, we find γ = 0.73 ± 0.28 and w = –1.007 ± 0.065, demonstrating that the

Preventative effect of OMZ-SPT on lipopolysaccharide-induced acute lung injury and inflammation via nuclear factor-kappa B signaling in mice

International Nuclear Information System (INIS)

Wang, Ting; Hou, Wanru; Fu, Zhou

2017-01-01

Acute lung injury (ALI) is an early pathophysiologic change in acute respiratory distress syndrome and its management can be challenging. Omalizumab (Xolair™) is a recombinant DNA-derived, humanized antibody. OMZ-SPT is a polypeptide on the heavy chain of omalizumab monoclonal antibody. Here, we found that intramuscular administration of OMZ-SPT significantly improved survival and attenuated lung inflammation in female C57BL/6 mice suffering from lipopolysaccharide (LPS)-induced ALI. We also demonstrated that OMZ-SPT can inhibit expression of the inflammatory cytokines tumor necrosis factor-α, interleukin-1β and interleukin-6 by ELISA in mice suffering from LPS-induced ALI and a mouse macrophage line (RAW264.7 cells). In addition, we showed that OMZ-SPT inhibited LPS-induced activation of nuclear factor-kappa B (NF-κB) signaling and total expression of NF-κB by western blotting. These data suggest that OMZ-SPT could be a novel therapeutic choice for ALI. - Highlights: • OMZ-SPT is a polypeptide on the heavy chain of omalizumab monoclonal antibody. • Omalizumab (Xolair™) have anti-inflammatory effects. • OMZ-SPT can inhibit inflammatory responses and lung injury in LPS-induced ALI mice. • Protective effect of OMZ-SPT on ALI is due to inhibition of NF-κB signaling. • OMZ-SPT could be a novel therapeutic choice for ALI.

Overburden Stress Normalization and Rod Length Corrections for the Standard Penetration Test (SPT)

OpenAIRE

Deger, Tonguc Tolga

2014-01-01

The Standard Penetration Test (SPT) has been a staple of geotechnical engineering practice for more than 70 years. Empirical correlations based on in situ SPT data provide an important basis for assessment of a broad range of engineering parameters, and for empirically based analysis and design methods spanning a significant number of areas of geotechnical practice. Despite this longstanding record of usage, the test itself is relatively poorly standardized with regard to the allowable variab...

Maps of the Southern Millimeter-wave Sky from Combined 2500 deg$^2$ SPT-SZ and Planck Temperature Data

Energy Technology Data Exchange (ETDEWEB)

Chown, R.; et al.

2018-03-28

We present three maps of the millimeter-wave sky created by combining data from the South Pole Telescope (SPT) and the Planck satellite. We use data from the SPT-SZ survey, a survey of 2540 deg$^2$ of the the sky with arcminute resolution in three bands centered at 95, 150, and 220 GHz, and the full-mission Planck temperature data in the 100, 143, and 217 GHz bands. A linear combination of the SPT-SZ and Planck data is computed in spherical harmonic space, with weights derived from the noise of both instruments. This weighting scheme results in Planck data providing most of the large-angular-scale information in the combined maps, with the smaller-scale information coming from SPT-SZ data. A number of tests have been done on the maps. We find their angular power spectra to agree very well with theoretically predicted spectra and previously published results.

MASS CALIBRATION AND COSMOLOGICAL ANALYSIS OF THE SPT-SZ GALAXY CLUSTER SAMPLE USING VELOCITY DISPERSION σ {sub v} AND X-RAY Y {sub X} MEASUREMENTS

Energy Technology Data Exchange (ETDEWEB)

Bocquet, S.; Saro, A.; Mohr, J. J.; Bazin, G.; Chiu, I.; Desai, S. [Department of Physics, Ludwig-Maximilians-Universität, Scheinerstr. 1, D-81679 München (Germany); Aird, K. A. [University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Ashby, M. L. N.; Bayliss, M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Bautz, M. [Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (United States); Benson, B. A. [Fermi National Accelerator Laboratory, Batavia, IL 60510-0500 (United States); Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Crawford, T. M.; Crites, A. T. [Kavli Institute for Cosmological Physics, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Brodwin, M. [Department of Physics and Astronomy, University of Missouri, 5110 Rockhill Road, Kansas City, MO 64110 (United States); Cho, H. M. [NIST Quantum Devices Group, 325 Broadway Mailcode 817.03, Boulder, CO 80305 (United States); Clocchiatti, A. [Departamento de Astronomia y Astrosifica, Pontificia Universidad Catolica (Chile); De Haan, T., E-mail: bocquet@usm.lmu.de [Department of Physics, McGill University, 3600 Rue University, Montreal, Quebec H3A 2T8 (Canada); and others

2015-02-01

We present a velocity-dispersion-based mass calibration of the South Pole Telescope Sunyaev-Zel'dovich effect survey (SPT-SZ) galaxy cluster sample. Using a homogeneously selected sample of 100 cluster candidates from 720 deg{sup 2} of the survey along with 63 velocity dispersion (σ {sub v}) and 16 X-ray Y {sub X} measurements of sample clusters, we simultaneously calibrate the mass-observable relation and constrain cosmological parameters. Our method accounts for cluster selection, cosmological sensitivity, and uncertainties in the mass calibrators. The calibrations using σ {sub v} and Y {sub X} are consistent at the 0.6σ level, with the σ {sub v} calibration preferring ∼16% higher masses. We use the full SPT{sub CL} data set (SZ clusters+σ {sub v}+Y {sub X}) to measure σ{sub 8}(Ω{sub m}/0.27){sup 0.3} = 0.809 ± 0.036 within a flat ΛCDM model. The SPT cluster abundance is lower than preferred by either the WMAP9 or Planck+WMAP9 polarization (WP) data, but assuming that the sum of the neutrino masses is ∑m {sub ν} = 0.06 eV, we find the data sets to be consistent at the 1.0σ level for WMAP9 and 1.5σ for Planck+WP. Allowing for larger ∑m {sub ν} further reconciles the results. When we combine the SPT{sub CL} and Planck+WP data sets with information from baryon acoustic oscillations and Type Ia supernovae, the preferred cluster masses are 1.9σ higher than the Y {sub X} calibration and 0.8σ higher than the σ {sub v} calibration. Given the scale of these shifts (∼44% and ∼23% in mass, respectively), we execute a goodness-of-fit test; it reveals no tension, indicating that the best-fit model provides an adequate description of the data. Using the multi-probe data set, we measure Ω{sub m} = 0.299 ± 0.009 and σ{sub 8} = 0.829 ± 0.011. Within a νCDM model we find ∑m {sub ν} = 0.148 ± 0.081 eV. We present a consistency test of the cosmic growth rate using SPT clusters. Allowing both the growth index γ and the dark energy equation

27 CFR 19.67 - Spirits produced in industrial processes.

Science.gov (United States)

2010-04-01

... industrial processes. 19.67 Section 19.67 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Administrative and Miscellaneous Provisions Activities Not Subject to This Part § 19.67 Spirits produced in industrial processes...

GALAXY CLUSTERS DISCOVERED VIA THE SUNYAEV-ZEL'DOVICH EFFECT IN THE 2500-SQUARE-DEGREE SPT-SZ SURVEY

Energy Technology Data Exchange (ETDEWEB)

Bleem, L. E.; Stalder, B.; de Haan, T.; Aird, K. A.; Allen, S. W.; Applegate, D. E.; Ashby, M. L. N.; Bautz, M.; Bayliss, M.; Benson, B. A.; Bocquet, S.; Brodwin, M.; Carlstrom, J. E.; Chang, C. L.; Chiu, I.; Cho, H. M.; Clocchiatti, A.; Crawford, T. M.; Crites, A. T.; Desai, S.; Dietrich, J. P.; Dobbs, M. A.; Foley, R. J.; Forman, W. R.; George, E. M.; Gladders, M. D.; Gonzalez, A. H.; Halverson, N. W.; Hennig, C.; Hoekstra, H.; Holder, G. P.; Holzapfel, W. L.; Hrubes, J. D.; Jones, C.; Keisler, R.; Knox, L.; Lee, A. T.; Leitch, E. M.; Liu, J.; Lueker, M.; Luong-Van, D.; Mantz, A.; Marrone, D. P.; McDonald, M.; McMahon, J. J.; Meyer, S. S.; Mocanu, L.; Mohr, J. J.; Murray, S. S.; Padin, S.; Pryke, C.; Reichardt, C. L.; Rest, A.; Ruel, J.; Ruhl, J. E.; Saliwanchik, B. R.; Saro, A.; Sayre, J. T.; Schaffer, K. K.; Schrabback, T.; Shirokoff, E.; Song, J.; Spieler, H. G.; Stanford, S. A.; Staniszewski, Z.; Stark, A. A.; Story, K. T.; Stubbs, C. W.; Vanderlinde, K.; Vieira, J. D.; Vikhlinin, A.; Williamson, R.; Zahn, O.; Zenteno, A.

2015-01-29

We present a catalog of galaxy clusters selected via their Sunyaev-Zel'dovich (SZ) effect signature from 2500 deg(2) of South Pole Telescope (SPT) data. This work represents the complete sample of clusters detected at high significance in the 2500 deg(2) SPT-SZ survey, which was completed in 2011. A total of 677 (409) cluster candidates are identified above a signal-to-noise threshold of ξ = 4.5 (5.0). Ground- and space-based optical and near-infrared (NIR) imaging confirms overdensities of similarly colored galaxies in the direction of 516 (or 76%) of the ξ > 4.5 candidates and 387 (or 95%) of the ξ > 5 candidates, the measured purity is consistent with expectations from simulations. Of these confirmed clusters, 415 were first identified in SPT data, including 251 new discoveries reported in this work. We estimate photometric redshifts for all candidates with identified optical and/or NIR counterparts, we additionally report redshifts derived from spectroscopic observations for 141 of these systems. The mass threshold of the catalog is roughly independent of redshift above z ~ 0.25 leading to a sample of massive clusters that extends to high redshift. The median mass of the sample is M (500c)(ρ(crit)) $\\sim 3.5\\times 10^{14}\\,M_\\odot \\,h_{70}^{-1}$, the median redshift is z (med) = 0.55, and the highest-redshift systems are at z > 1.4. The combination of large redshift extent, clean selection, and high typical mass makes this cluster sample of particular interest for cosmological analyses and studies of cluster formation and evolution.

NCBI nr-aa BLAST: CBRC-SARA-01-1967 [SEVENS

Lifescience Database Archive (English)

Full Text Available CBRC-SARA-01-1967 ref|ZP_00370594.1| Predicted DNA repair exonuclease [Campylobacter upsaliens...is RM3195] gb|EAL53370.1| Predicted DNA repair exonuclease [Campylobacter upsaliensis RM3195] ZP_00370594.1 0.047 31% ...

Fast SPT-Term Allocation and Efficient FPGA Implementation of FIR Filters for Software Defined Radio Applications

OpenAIRE

Bae, Choonghoon; Moteki, Takayuki; Kim, Minseok; Ichige, Koichi; Arai, Hiroyuki

2009-01-01

This paper presents a fast SPT-term allocation scheme and an efficient FPGA implementation of FIR filters for Software Defined Radio (SDR) applications. Direct conversion method based on RF direct sampling is nowadays widely used in SDR applications. Fast and accurate digital filters are required for RF direct sampling and processing in direct conversion, however such filters often require large digital circuit area. Signed-Power-of-Two (SPT) terms will be suitable for fast processing and eff...

The Spt-Ada-Gcn5 Acetyltransferase (SAGA complex in Aspergillus nidulans.

Directory of Open Access Journals (Sweden)

Paraskevi Georgakopoulos

Full Text Available A mutation screen in Aspergillus nidulans uncovered mutations in the acdX gene that led to altered repression by acetate, but not by glucose. AcdX of A. nidulans is highly conserved with Spt8p of Saccharomyces cerevisiae, and since Spt8p is a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA complex, the SAGA complex may have a role in acetate repression in A. nidulans. We used a bioinformatic approach to identify genes encoding most members of the SAGA complex in A. nidulans, and a proteomic analysis to confirm that most protein components identified indeed exist as a complex in A. nidulans. No apparent compositional differences were detected in mycelia cultured in acetate compared to glucose medium. The methods used revealed apparent differences between Yeast and A. nidulans in the deubiquitination (DUB module of the complex, which in S. cerevisiae consists of Sgf11p, Sus1p, and Ubp8p. Although a convincing homologue of S. cerevisiae Ubp8p was identified in the A. nidulans genome, there were no apparent homologues for Sus1p and Sgf11p. In addition, when the SAGA complex was purified from A. nidulans, members of the DUB module were not co-purified with the complex, indicating that functional homologues of Sus1p and Sgf11p were not part of the complex. Thus, deubiquitination of H2B-Ub in stress conditions is likely to be regulated differently in A. nidulans compared to S. cerevisiae.

THE REDSHIFT DISTRIBUTION OF DUSTY STAR-FORMING GALAXIES FROM THE SPT SURVEY

Energy Technology Data Exchange (ETDEWEB)

Strandet, M. L.; Weiss, A. [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69 D-53121 Bonn (Germany); Vieira, J. D.; Furstenau, R. M. [European Southern Observatory, Karl Schwarzschild Straße 2, D-85748 Garching (Germany); De Breuck, C.; Béthermin, M.; Gullberg, B. [Department of Astronomy and Department of Physics, University of Illinois, 1002 West Green St., Urbana, IL 61801 (United States); Aguirre, J. E. [University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104 (United States); Aravena, M. [Núcleo de Astronomía, Facultad de Ingeniería, Universidad Diego Portales, Av. Ejército 441, Santiago (Chile); Ashby, M. L. N. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Bradford, C. M. [Jet Propulsion Laboratory, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States); Carlstrom, J. E.; Crawford, T. M. [Kavli Institute for Cosmological Physics, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Chapman, S. C. [Dalhousie University, Halifax, Nova Scotia (Canada); Everett, W. [Department of Astrophysical and Planetary Sciences and Department of Physics, University of Colorado, Boulder, CO 80309 (United States); Fassnacht, C. D. [Department of Physics, University of California, One Shields Avenue, Davis, CA 95616 (United States); Gonzalez, A. H. [Department of Astronomy, University of Florida, Gainesville, FL 32611 (United States); Greve, T. R. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Hezaveh, Y. [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Stanford, CA 94305 (United States); and others

2016-05-10

We use the Atacama Large Millimeter/submillimeter Array (ALMA) in Cycle 1 to determine spectroscopic redshifts of high-redshift dusty star-forming galaxies (DSFGs) selected by their 1.4 mm continuum emission in the South Pole Telescope (SPT) survey. We present ALMA 3 mm spectral scans between 84 and 114 GHz for 15 galaxies and targeted ALMA 1 mm observations for an additional eight sources. Our observations yield 30 new line detections from CO, [C i], [N ii], H{sub 2}O and NH{sub 3}. We further present Atacama Pathfinder Experiment [C ii] and CO mid- J observations for seven sources for which only a single line was detected in spectral-scan data from ALMA Cycle 0 or Cycle 1. We combine the new observations with previously published and new millimeter/submillimeter line and photometric data of the SPT-selected DSFGs to study their redshift distribution. The combined data yield 39 spectroscopic redshifts from molecular lines, a success rate of >85%. Our sample represents the largest data set of its kind today and has the highest spectroscopic completeness among all redshift surveys of high- z DSFGs. The median of the redshift distribution is z = 3.9 ± 0.4, and the highest-redshift source in our sample is at z = 5.8. We discuss how the selection of our sources affects the redshift distribution, focusing on source brightness, selection wavelength, and strong gravitational lensing. We correct for the effect of gravitational lensing and find the redshift distribution for 1.4 mm selected sources with a median redshift of z = 3.1 ± 0.3. Comparing to redshift distributions selected at shorter wavelengths from the literature, we show that selection wavelength affects the shape of the redshift distribution.

Constraints on Cosmological Parameters from the Angular Power Spectrum of a Combined 2500 deg$^2$ SPT-SZ and Planck Gravitational Lensing Map

Energy Technology Data Exchange (ETDEWEB)

Simard, G.; et al.

2017-12-20

We report constraints on cosmological parameters from the angular power spectrum of a cosmic microwave background (CMB) gravitational lensing potential map created using temperature data from 2500 deg$^2$ of South Pole Telescope (SPT) data supplemented with data from Planck in the same sky region, with the statistical power in the combined map primarily from the SPT data. We fit the corresponding lensing angular power spectrum to a model including cold dark matter and a cosmological constant ($\\Lambda$CDM), and to models with single-parameter extensions to $\\Lambda$CDM. We find constraints that are comparable to and consistent with constraints found using the full-sky Planck CMB lensing data. Specifically, we find $\\sigma_8 \\Omega_{\\rm m}^{0.25}=0.598 \\pm 0.024$ from the lensing data alone with relatively weak priors placed on the other $\\Lambda$CDM parameters. In combination with primary CMB data from Planck, we explore single-parameter extensions to the $\\Lambda$CDM model. We find $\\Omega_k = -0.012^{+0.021}_{-0.023}$ or $M_{\

Space power technology for the twenty-first century (SPT21)

International Nuclear Information System (INIS)

Borger, W.U.; Massie, L.D.

1988-01-01

During the spring and summer months of 1987, the Aero Propulsion Laboratory of the Air Force Wright Aeronautical Laboratories, Wright-Patterson AFB, Ohio in cooperation with the Air Force Space Technology Center at Kirtland AFB, New Mexico, undertook an initiative to develop a Strategic Plan for Space Power Technology Development. The initiative was called SPT21, Space Power Technology for the Twenty-First Century. The planning process involved the participation of other Government organizations (U.S. Army, Navy, DOE and NASA) along with major aerospace companies and universities. Following an SPT21 kickoff meeting on 28 May 1987, detailed strategic planning was accomplished through seven (7) Space Power Technology Discipline Workshops commencing in June 1987 and concluding in August 1987. Technology Discipline Workshops were conducted in the following areas: (1) Solar Thermal Dynamic Power Systems (2) Solar Photovoltaic Cells and Arrays (3) Thermal Management Technology (4) Energy Storage Technology (5) Nuclear Power Systems Technology (6) Power Conditioning, Distribution and Control and (7) Systems Technology/Advanced Concepts. This technical paper summarizes the planning process and describes the salient findings and conclusions of the workshops

The New Arab Left and 1967

DEFF Research Database (Denmark)

Haugbølle, Sune

2017-01-01

In Arab political culture, the Naksa of 1967 had a number of watershed effects. Scholars have paid a lot of attention to the decline of secular Arab nationalism and the concurrent rise of Islamism. Much less research has been done on the way 1967 spurred radical left organizations, also known as ...... moment that followed. This moment has had a lasting impact on Arab political culture and is being re-interpreted in interesting ways today by Arab revolutionaries post-2011....

Subsidence of Surtsey volcano, 1967-1991

Science.gov (United States)

Moore, J.G.; Jakobsson, S.; Holmjarn, J.

1992-01-01

The Surtsey marine volcano was built on the southern insular shelf of Iceland, along the seaward extension of the east volcanic zone, during episodic explosive and effusive activity from 1963 to 1967. A 1600-m-long, east-west line of 42 bench marks was established across the island shortly after volcanic activity stopped. From 1967 to 1991 a series of leveling surveys measured the relative elevation of the original bench marks, as well as additional bench marks installed in 1979, 1982 and 1985. Concurrent measurements were made of water levels in a pit dug on the north coast, in a drill hole, and along the coastline exposed to the open ocean. These surveys indicate that the dominant vertical movement of Surtsey is a general subsidence of about 1.1??0.3 m during the 24-year period of observations. The rate of subsidence decreased from 15-20 cm/year for 1967-1968 to 1-2 cm/year in 1991. Greatest subsidence is centered about the eastern vent area. Through 1970, subsidence was locally greatest where the lava plain is thinnest, adjacent to the flanks of the eastern tephra cone. From 1982 onward, the region closest to the hydrothermal zone, which is best developed in the vicinity of the eastern vent, began showing less subsidence relative to the rest of the surveyed bench marks. The general subsidence of the island probably results from compaction of the volcanic material comprising Surtsey, compaction of the sea-floor sediments underlying the island, and possibly downwarping of the lithosphere due to the laod of Surtsey. The more localized early downwarping near the eastern tephra cone is apparently due to greater compaction of tephra relative to lava. The later diminished local subsidence near the hydrothermal zone is probably due to a minor volume increase caused by hydrous alteration of glassy tephra. However, this volume increase is concentrated at depth beneath the bottom of the 176-m-deep cased drillhole. ?? 1992 Springer-Verlag.

Joint measurement of lensing–galaxy correlations using SPT and DES SV data

Energy Technology Data Exchange (ETDEWEB)

Baxter, E.; Clampitt, J.; Giannantonio, T.; Dodelson, S.; Jain, B.; Huterer, D.; Bleem, L.; Crawford, T.; Efstathiou, G.; Fosalba, P.; Kirk, D.; Kwan, J.; Sánchez, C.; Story, K.; Troxel, M. A.; Abbott, T. M. C.; Abdalla, F. B.; Armstrong, R.; Benoit-Lévy, A.; Benson, B.; Bernstein, G. M.; Bernstein, R. A.; Bertin, E.; Brooks, D.; Carlstrom, J.; Rosell, A. Carnero; Carrasco Kind, M.; Carretero, J.; Chown, R.; Crocce, M.; Cunha, C. E.; da Costa, L. N.; Desai, S.; Diehl, H. T.; Dietrich, J. P.; Doel, P.; Evrard, A. E.; Fausti Neto, A.; Flaugher, B.; Frieman, J.; Gruen, D.; Gruendl, R. A.; Gutierrez, G.; de Haan, T.; Holder, G.; Honscheid, K.; Hou, Z.; James, D. J.; Kuehn, K.; Kuropatkin, N.; Lima, M.; March, M.; Marshall, J. L.; Martini, P.; Melchior, P.; Miller, C. J.; Miquel, R.; Mohr, J. J.; Nord, B.; Omori, Y.; Plazas, A. A.; Reichardt, C.; Romer, A. K.; Rykoff, E. S.; Sanchez, E.; Sevilla-Noarbe, I.; Sheldon, E.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Stark, A.; Swanson, M. E. C.; Tarle, G.; Thomas, D.; Walker, A. R.; Wechsler, R. H.

2016-07-04

We measure the correlation of galaxy lensing and cosmic microwave background lensing with a set of galaxies expected to trace the matter density field. The measurements are performed using pre-survey Dark Energy Survey (DES) Science Verification optical imaging data and millimetre-wave data from the 2500 sq. deg. South Pole Telescope Sunyaev–Zel'dovich (SPT-SZ) survey. The two lensing–galaxy correlations are jointly fit to extract constraints on cosmological parameters, constraints on the redshift distribution of the lens galaxies, and constraints on the absolute shear calibration of DES galaxy-lensing measurements. We show that an attractive feature of these fits is that they are fairly insensitive to the clustering bias of the galaxies used as matter tracers. The measurement presented in this work confirms that DES and SPT data are consistent with each other and with the currently favoured Λ cold dark matter cosmological model. It also demonstrates that joint lensing–galaxy correlation measurement considered here contains a wealth of information that can be extracted using current and future surveys.

Analisis Penerapan E-spt Dan E-filing Dalam Upaya Peningkatan Kepatuhan Wajib Pajak (Studi Kasus Di Kantor Pelayanan Pajak Pratama Manado)

OpenAIRE

Tumuli, Apriliani Kasandra; Sondakh, Jullie J; Wokas, Heince R.N

2016-01-01

Direktorat Jenderal Pajak melakukan berbagai inovasi baru dalam bidang perpajakan yaitu dengan pemanfaatan teknologi dan informasi sehingga terciptalah aplikasi komputer dalam sistem administrasi perpajakan seperti e-SPT dan e-Filing untuk memudahklan para wajib pajak sehingga dapat meningkatkan kepatuhan wajib pajak dalam melaporkan kewajiban perpajakannya. Penelitian ini bertujuan untuk mengetahui tingkat penggunaan e-SPT dan e-Filing, tingkat kepatuhan wajib pajak yaitu ketepatan waktu mel...

Fundamentos e métodos de medidas de energia dinâmica no SPT

Directory of Open Access Journals (Sweden)

Antonio Belincanta

2000-05-01

Full Text Available Discutem-se neste trabalho os métodos disponíveis no Brasil e no exterior para a medida da energia transferida às hastes no SPT, apresentando-se inclusive registros típicos dos eventos dinâmicos correspondentes

Zooplankton and other data collected from net casts in Coastal Waters of California from T-441; 19 April 1967 to 13 September 1967 (NODC Accession 7101507)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Zooplankton and other data were collected using net casts from T-441 in the Coastal Waters of California. Data were collected from 19 April 1967 to 13 September 1967...

Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.

Directory of Open Access Journals (Sweden)

Craig B Bennett

2008-01-01

Full Text Available BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 functions, we screened the evolutionarily distant eukaryote Saccharomyces cerevisiae for mutants that suppressed the G1 checkpoint arrest and lethality induced following heterologous BRCA1 expression. A genome-wide screen in the diploid deletion collection combined with a screen of ionizing radiation sensitive gene deletions identified mutants that permit growth in the presence of BRCA1. These genes delineate a metabolic mRNA pathway that temporally links transcription elongation (SPT4, SPT5, CTK1, DEF1 to nucleopore-mediated mRNA export (ASM4, MLP1, MLP2, NUP2, NUP53, NUP120, NUP133, NUP170, NUP188, POM34 and cytoplasmic mRNA decay at P-bodies (CCR4, DHH1. Strikingly, BRCA1 interacted with the phosphorylated RNA polymerase II (RNAPII carboxy terminal domain (P-CTD, phosphorylated in the pattern specified by the CTDK-I kinase, to induce DEF1-dependent cleavage and accumulation of a RNAPII fragment containing the P-CTD. Significantly, breast cancer associated BRCT domain defects in BRCA1 that suppressed P-CTD cleavage and lethality in yeast also suppressed the physical interaction of BRCA1 with human SPT5 in breast epithelial cells, thus confirming SPT5 as a relevant target of BRCA1 interaction. Furthermore, enhanced P-CTD cleavage was observed in both yeast and human breast cells following UV-irradiation indicating a conserved eukaryotic damage response. Moreover, P-CTD cleavage in breast epithelial cells was BRCA1-dependent since damage-induced P-CTD cleavage was only observed in the mutant BRCA1 cell line HCC1937 following ectopic expression of wild type BRCA1. Finally, BRCA1, SPT5 and hyperphosphorylated RPB1 form a complex that was rapidly degraded following MMS treatment in wild type but not BRCA1

Cancer incidence rates and trends among children and adolescents in Piedmont, 1967-2011.

Science.gov (United States)

Isaevska, Elena; Manasievska, Milena; Alessi, Daniela; Mosso, Maria Luisa; Magnani, Corrado; Sacerdote, Carlotta; Pastore, Guido; Fagioli, Franca; Merletti, Franco; Maule, Milena

2017-01-01

In the past, increases in childhood cancer incidence were reported in Europe and North America. The aim of this study is to show updated patterns of temporal behavior using data of the Childhood Cancer Registry of Piedmont (CCRP), a region with approximately 4.5 million inhabitants in North-West Italy. CCRP has been recording incident cases in children (0-14 years) since 1967 and in adolescents (15-19) since 2000. Time trends were estimated as annual percent change (APC) over the 1976-2011 period for children, and over 2000-2011 for both children and adolescents. CCRP registered 5020 incident cases from 1967 to 2011. Incidence rates were 157 per million person-years for children (1967-2011) and 282 for adolescents (2000-2011). From 1976-2011, increasing trends were observed in children for all neoplasms (APC 1.1, 95%CI: 0.8; 1.5) and for both embryonal and non-embryonal tumors: 1.1%, (0.5; 1.6) and 1.2%, (0.7; 1.6), respectively. Increases were observed in several tumor types, including leukemia, lymphoma, central nervous system tumors and neuroblastoma. In 2000-2011, incidence rates showed mostly non statistically significant variations and large variability. The observation of trends over a long period shows that the incidence of most tumors has increased, and this is only partially explained by diagnostic changes. Large rate variability hampers interpretation of trend patterns in short periods. Given that no satisfying explanation for the increases observed in the past was ever found, efforts must be made to understand and interpret this peculiar and still ununderstood pattern of childhood cancer incidence.

Cancer incidence rates and trends among children and adolescents in Piedmont, 1967-2011.

Directory of Open Access Journals (Sweden)

Elena Isaevska

Full Text Available In the past, increases in childhood cancer incidence were reported in Europe and North America. The aim of this study is to show updated patterns of temporal behavior using data of the Childhood Cancer Registry of Piedmont (CCRP, a region with approximately 4.5 million inhabitants in North-West Italy. CCRP has been recording incident cases in children (0-14 years since 1967 and in adolescents (15-19 since 2000. Time trends were estimated as annual percent change (APC over the 1976-2011 period for children, and over 2000-2011 for both children and adolescents. CCRP registered 5020 incident cases from 1967 to 2011. Incidence rates were 157 per million person-years for children (1967-2011 and 282 for adolescents (2000-2011. From 1976-2011, increasing trends were observed in children for all neoplasms (APC 1.1, 95%CI: 0.8; 1.5 and for both embryonal and non-embryonal tumors: 1.1%, (0.5; 1.6 and 1.2%, (0.7; 1.6, respectively. Increases were observed in several tumor types, including leukemia, lymphoma, central nervous system tumors and neuroblastoma. In 2000-2011, incidence rates showed mostly non statistically significant variations and large variability. The observation of trends over a long period shows that the incidence of most tumors has increased, and this is only partially explained by diagnostic changes. Large rate variability hampers interpretation of trend patterns in short periods. Given that no satisfying explanation for the increases observed in the past was ever found, efforts must be made to understand and interpret this peculiar and still ununderstood pattern of childhood cancer incidence.

38 CFR 1.967 - Refunds.

Science.gov (United States)

2010-07-01

... Referrals to Gao, Department of Justice, Or Irs § 1.967 Refunds. (a) Except as provided in paragraph (c) of... educational institution found liable under 38 U.S.C. 3685. Waiver of collection of educational benefit overpayments from all or a portion of the eligible persons attending an educational institution which has been...

Cuadros en movimiento: la pintura en el cine: Relaciones intermediales en La hora de los valientes [Mercero 1998] y Te doy mis ojos [Bollaín 2003

Directory of Open Access Journals (Sweden)

Esther Gimeno Ugalde

2011-12-01

Full Text Available The objective of this article is to study the relationship between cinema and painting from an intermedial perspective by analysing two Spanish films: La hora de los valientes (Antonio Mercero 1998 and Te doy mis ojos (Icíar Bollaín 2003. We intend to compare how the respective directors use painting to construct and enrich the cinematographic story and to analyse what narrative and artistic role the paintings play in the filmic text. The study of the two films will serve to illustrate our initial hypothesis, that painting is used not only for artistic and narrative purposes, but also to make the spectator a witness of a twofold drama: the individual and the collective. The exchange of looks which permeates the diegesis places painting to the forefront, whilst determining the interpretation of the filmic textBasándonos en un enfoque teórico intermedial, el presente artículo tiene como objeto estudiar las relaciones entre cine y pintura a partir de dos películas españolas: La hora de los valientes [Antonio Mercero 1998] y Te doy mis ojos [Icíar Bollaín 2003]. Nos proponemos cotejar cómo los respectivos directores introducen la pintura para construir y enriquecer el relato cinematográfico y analizar qué función narrativa y estética cumplen los cuadros en el texto fílmico. El estudio de ambos filmes nos servirá para demostrar nuestra hipótesis inicial: la pintura se emplea no solo con fines estéticos y narrativos, sino también para convertir al espectador en testigo de un doble drama, el individual y el colectivo. El juego de miradas que atraviesa la diégesis sitúa a la pintura en un primer plano, a la vez que determina la lectura del texto fílmico

The augmentation of heat transfer in a pipe flow using a swirling perforated twisted (SPT) tape insert

Science.gov (United States)

Ahmad, Shahrokh; Oishe, Sadia Noon; Rahman, Md. Lutfor

2017-12-01

The purpose of this research work is to increase the heat transfer coefficient by operating the heat exchangers at smaller revolution per minute. This signifies an achievement of reduction of pressure drop corresponding to less operating cost. This study has used two types of SPT tape insert to observe the various heat transfer coefficient, heat transfer rate and heat transfer augmentation efficiency. One tape was fully twisted and another tape was partially twisted. The shape of the SPT tape creates turbulence effect. The turbulence flow (swirl flow) generated by SPT tape promotes greater mixing and high heat transfer coefficients. An arrangement scheme has been developed for the experimental investigation. For remarking the rate of change of heat transfer, temperature has been measured numerically through the temperature sensors with various flow rates and RPM. The volume flow rate was varied from 10.3448276 LPM to 21.045574 LPM and the rotation of the perforated twisted tape was varied from 50 RPM to 400 RPM. Finally the research study demonstrates the effectiveness of the results of the proposed approaches. It is observed that the suggested method of heat transfer augmentations is much more effective than existing methods, since it results in an increase in heat transfer area and also an increase in the heat transfer coefficient and reduction of cost in the industrial sectors.

Detection of a Double Relic in the Torpedo Cluster: SPT-CL J0245-5302

Science.gov (United States)

Zheng, Q.; Johnston-Hollitt, M.; Duchesne, S. W.; Li, W. T.

2018-06-01

The Torpedo cluster, SPT-CL J0245-5302 (S0295) is a massive, merging cluster at a redshift of z = 0.300, which exhibits a strikingly similar morphology to the Bullet cluster 1E 0657-55.8 (z = 0.296), including a classic bow shock in the cluster's intra-cluster medium revealed by Chandra X-ray observations. We present Australia Telescope Compact Array data centred at 2.1 GHz and Murchison Widefield Array data at frequencies between 72 MHz and 231 MHz which we use to study the properties of the cluster. We characterise a number of discrete and diffuse radio sources in the cluster, including the detection of two previously unknown radio relics on the cluster periphery. The average spectral index of the diffuse emission between 70 MHz and 3.1 GHz is α =-1.63_{-0.10}^{+0.10} and a radio-derived Mach number for the shock in the west of the cluster is calculated as M = 2.04. The Torpedo cluster is thus a double relic system at moderate redshift.

A (Small) complexity performance contest: SPT versus LBFS

DEFF Research Database (Denmark)

Nielsen, Erland Hejn

2002-01-01

When discussing the nature of loading rules relevant to continuous dynamic job/flow shop systems, the general understanding is that results obtained in simpler structures of 2 to 4 machines are invariant to scaling and can be generalised without problems to more complex structures. The SPT...... results on pure re-entrant flow shop structures emerges. It now seems that alternative loading rules as for instance the LBFS (Last Buffer First Served) due to its strong long run stabilising property attracts quite some interest. To be more precise about the complexity aspect, complexity in job...... are not entirely only of theoretical interest, as well as results from a standard serial job/flow shop set-up, but with resource limitations that prevent the independent operations of the individual stations in the system....

A (Small) Complexity Performance Contest: SPT versus LBFS

DEFF Research Database (Denmark)

Nielsen, Erland Hejn

2002-01-01

When discussing the nature of loading rules relevant to continuous dynamic job/flow shop systems, the general understanding is that results obtained in simpler structures of 2 to 4 machines are invariant to scaling and can be generalised without problems to more complex structures. The SPT...... results on pure re-entrant flow shop structures emerges. It now seems that alternative loading rules as for instance the LBFS (Last Buffer First Served) due to its strong long run stabilising property attracts quite some interest. To be more precise about the complexity aspect, complexity in job...... are not entirely only of theoretical interest, as well as results from a standard serial job/flow shop set-up, but with resource limitations that prevent the independent operations of the individual stations in the system....

Report on the Personnel Dosimetry at AB Atomenergi during 1967

International Nuclear Information System (INIS)

Carlsson, J.; Wahlberg, T.

1968-12-01

This report presents the results of personnel dosimetry at AB Atomenergi during 1967. The external total body gamma dose for all employees (quarterly doses ≤ 100 mrem are not reported) corresponds to 140 manrem. The highest external total body gamma dose during 1967 to one person was 5700 mrem. 24700 gamma films and 3900 neutron films were evaluated. 1988 urine analyses and 989 measurements of body activity were made

Report on the Personnel Dosimetry at AB Atomenergi during 1967

Energy Technology Data Exchange (ETDEWEB)

Carlsson, J; Wahlberg, T

1968-12-15

This report presents the results of personnel dosimetry at AB Atomenergi during 1967. The external total body gamma dose for all employees (quarterly doses {<=} 100 mrem are not reported) corresponds to 140 manrem. The highest external total body gamma dose during 1967 to one person was 5700 mrem. 24700 gamma films and 3900 neutron films were evaluated. 1988 urine analyses and 989 measurements of body activity were made.

Impaired Uptake and/or Utilization of Leucine by Saccharomyces cerevisiae Is Suppressed by the SPT15-300 Allele of the TATA-Binding Protein Gene

DEFF Research Database (Denmark)

Baerends, RJ; Qiu, Jin-Long; Rasmussen, Simon

2009-01-01

Successful fermentations to produce ethanol require microbial strains that have a high tolerance to glucose and ethanol. Enhanced glucose/ethanol tolerance of the laboratory yeast Saccharomyces cerevisiae strain BY4741 under certain growth conditions as a consequence of the expression of a dominant...... us to examine the effect of expression of the SPT15-300 allele in various yeast species of industrial importance. Expression of SPT15-300 in leucine-prototrophic strains of S. cerevisiae, Saccharomyces bayanus, or Saccharomyces pastorianus (lager brewing yeast), however, did not improve tolerance...... to ethanol on complex rich medium (yeast extract-peptone-dextrose). The enhanced growth of the laboratory yeast strain BY4741 expressing the SPT15-300 mutant allele was seen only on defined media with low concentrations of leucine, indicating that the apparent improved growth in the presence of ethanol...

Integration Tests of the 4 kW-class High Voltage Hall Accelerator Power Processing Unit with the HiVHAc and the SPT-140 Hall Effect Thrusters

Science.gov (United States)

Kamhawi, Hani; Pinero, Luis; Haag, Thomas; Huang, Wensheng; Ahern, Drew; Liang, Ray; Shilo, Vlad

2016-01-01

NASAs Science Mission Directorate is sponsoring the development of a 4 kW-class Hall propulsion system for implementation in NASA science and exploration missions. The main components of the system include the High Voltage Hall Accelerator (HiVHAc), an engineering model power processing unit (PPU) developed by Colorado Power Electronics, and a xenon flow control module (XFCM) developed by VACCO Industries. NASA Glenn Research Center is performing integrated tests of the Hall thruster propulsion system. This presentation presents results from integrated tests of the PPU and XFCM with the HiVHAc engineering development thruster and a SPT-140 thruster provided by Space System Loral. The results presented in this paper demonstrate thruster discharge initiation, open-loop and closed-loop control of the discharge current with anode flow for both the HiVHAc and the SPT-140 thrusters. Integrated tests with the SPT-140 thruster indicated that the PPU was able to repeatedly initiate the thrusters discharge, achieve steady state operation, and successfully throttle the thruster between 1.5 and 4.5 kW. The measured SPT-140 performance was identical to levels reported by Space Systems Loral.

Sunyaev-Zel'dovich Effect and X-ray Scaling Relations from Weak-Lensing Mass Calibration of 32 SPT Selected Galaxy Clusters

Energy Technology Data Exchange (ETDEWEB)

Dietrich, J.P.; et al.

2017-11-14

Uncertainty in the mass-observable scaling relations is currently the limiting factor for galaxy cluster based cosmology. Weak gravitational lensing can provide a direct mass calibration and reduce the mass uncertainty. We present new ground-based weak lensing observations of 19 South Pole Telescope (SPT) selected clusters and combine them with previously reported space-based observations of 13 galaxy clusters to constrain the cluster mass scaling relations with the Sunyaev-Zel'dovich effect (SZE), the cluster gas mass $M_\\mathrm{gas}$, and $Y_\\mathrm{X}$, the product of $M_\\mathrm{gas}$ and X-ray temperature. We extend a previously used framework for the analysis of scaling relations and cosmological constraints obtained from SPT-selected clusters to make use of weak lensing information. We introduce a new approach to estimate the effective average redshift distribution of background galaxies and quantify a number of systematic errors affecting the weak lensing modelling. These errors include a calibration of the bias incurred by fitting a Navarro-Frenk-White profile to the reduced shear using $N$-body simulations. We blind the analysis to avoid confirmation bias. We are able to limit the systematic uncertainties to 6.4% in cluster mass (68% confidence). Our constraints on the mass-X-ray observable scaling relations parameters are consistent with those obtained by earlier studies, and our constraints for the mass-SZE scaling relation are consistent with the the simulation-based prior used in the most recent SPT-SZ cosmology analysis. We can now replace the external mass calibration priors used in previous SPT-SZ cosmology studies with a direct, internal calibration obtained on the same clusters.

Evaluation of SPT energy for Donut and Safety hammers using CPT measurements in Egypt

OpenAIRE

Rami M. El-Sherbiny; Manal A. Salem

2013-01-01

Standard Penetration Test (SPT) blow counts require correction prior to utilization in soil characterization and determination of properties and behavior. Among the most important corrections is the energy correction required to adjust the blow counts to 60% energy efficiency. However, there are no published data supporting commonly used value in Egypt. This paper presents an evaluation of the energy efficiency of the Donut and Safety hammers commonly used in Egypt and the associated energy c...

Pengaruh Customer Relationship Management Terhadap Loyalitas Nasabah Pada PT. Asuransi Umum Bumiputera Muda 1967 Cabang Pekanbaru

OpenAIRE

Sari, Wulan; Sutrisna, Endang

2017-01-01

The purpose of this study was to analyze the Customer Relationship Management and Customer Loyalty at PT. General Insurance Bumiputera Muda 1967 Pekanbaru Branch and see the effects. The study concluded that CRM at PT. General Insurance Bumiputera Muda 1967 Pekanbaru Branch which include dimensions, people, process and technology. Overall is considered to be good. Customer loyalty in the PT. General Insurance Bumiputera Muda 1967 Pekanbaru Branch is seen from the dimensions make the purchase ...

1967 : six days on the front

Energy Technology Data Exchange (ETDEWEB)

Anon.

2008-06-15

Canada's first oil sands project was launched by the Great Canadian Oil Sands Company in 1967 near Fort McMurray, Alberta. Giant draglines and bucketwheel excavators were used to mine the abrasive bitumen-laden sands. The first Middle East crisis also spiked demand for Canadian oil. The combined output from Algeria, Libya, Egypt and the Persian Gulf countries was 11.5 million barrels per day compared to just under 27 million barrels per day total free world production. The short crisis directly threatened Quebec and the Atlantic provinces which were entirely dependent on imported petroleum. Although western Canada had the ability to increase production by nearly 300,000 barrels per day, inadequate pipeline capacity impeded delivery of Canadian oil to these provinces. Following the crisis, production from the Persian Gulf and North Africa actually increased by 900,000 barrels per day. The long-term effect of the crisis was the closing of the Suez Canal for 8 years, depriving it of tariff revenues and permanently changing world shipping routes. In 1967, the first liquefied natural gas plant also came on stream in Vancouver, and Mobil Oil drilled a 15,000-foot exploratory well on Sable Island, Nova Scotia. 1 tab., 1 fig.

Expression of a mutated SPT15 gene in Saccharomyces cerevisiae enhances both cell growth and ethanol production in microaerobic batch, fed-batch, and simultaneous saccharification and fermentations.

Science.gov (United States)

Seong, Yeong-Je; Park, Haeseong; Yang, Jungwoo; Kim, Soo-Jung; Choi, Wonja; Kim, Kyoung Heon; Park, Yong-Cheol

2017-05-01

The SPT15 gene encodes a Saccharomyces cerevisiae TATA-binding protein, which is able to globally control the transcription levels of various metabolic and regulatory genes. In this study, a SPT15 gene mutant (S42N, S78R, S163P, and I212N) was expressed in S. cerevisiae BY4741 (BSPT15-M3), of which effects on fermentative yeast properties were evaluated in a series of culture types. By applying different nitrogen sources and air supply conditions in batch culture, organic nitrogen sources and microaerobic condition were decided to be more favorable for both cell growth and ethanol production of the BSPT15-M3 strain than the control S. cerevisiae BY4741 strain expressing the SPT15 gene (BSPT15wt). Microaerobic fed-batch cultures of BSPT15-M3 with glucose shock in the presence of high ethanol content resulted in a 9.5-13.4% higher glucose consumption rate and ethanol productivity than those for the BSPT15wt strain. In addition, BSPT15-M3 showed 4.5 and 3.9% increases in ethanol productivity from cassava hydrolysates and corn starch in simultaneous saccharification and fermentation processes, respectively. It was concluded that overexpression of the mutated SPT15 gene would be a potent strategy to develop robust S. cerevisiae strains with enhanced cell growth and ethanol production abilities.

Sessile oak (Quercus petraea agg. Ehrendorfer 1967) rare ...

African Journals Online (AJOL)

Sessile oak ( Quercus petraea agg. Ehrendorfer 1967) genetic variability in Serbia was estimated applying cpDNA universal primer pairs. Five different haplotypes were detected in the analyzed sample material from populations in Serbia. The areas in West and Southwest Serbia, with all their specificities, represent an ...

The Effect of Economic Inflation on Local Public Library Support in Kentucky, 1967-1976.

Science.gov (United States)

Smith, Robert C.

This study was developed on the hypothesis that economic inflation reduced the purchasing power of local support for public libraries from 1967 through fiscal 1976. The total local support for public libraries in each county in each year of the study was adjusted from the reported nominal amount to the relative Consumer Price Index value of 1967…

Effects of inhibition of serine palmitoyltransferase (SPT and sphingosine kinase 1 (SphK1 on palmitate induced insulin resistance in L6 myotubes.

Directory of Open Access Journals (Sweden)

Agnieszka Mikłosz

Full Text Available BACKGROUND: The objective of this study was to examine the effects of short (2 h and prolonged (18 h inhibition of serine palmitoyltransferase (SPT and sphingosine kinase 1 (SphK1 on palmitate (PA induced insulin resistance in L6 myotubes. METHODS: L6 myotubes were treated simultaneously with either PA and myriocin (SPT inhibitor or PA and Ski II (SphK1inhibitor for different time periods (2 h and 18 h. Insulin stimulated glucose uptake was measured using radioactive isotope. Expression of insulin signaling proteins was determined using Western blot analyses. Intracellular sphingolipids content [sphinganine (SFA, ceramide (CER, sphingosine (SFO, sphingosine-1-phosphate (S1P] were estimated by HPLC. RESULTS: Our results revealed that both short and prolonged time of inhibition of SPT by myriocin was sufficient to prevent ceramide accumulation and simultaneously reverse palmitate induced inhibition of insulin-stimulated glucose transport. In contrast, prolonged inhibition of SphK1 intensified the effect of PA on insulin-stimulated glucose uptake and attenuated further the activity of insulin signaling proteins (pGSK3β/GSK3β ratio in L6 myotubes. These effects were related to the accumulation of sphingosine in palmitate treated myotubes. CONCLUSION: Myriocin is more effective in restoration of palmitate induced insulin resistance in L6 myocytes, despite of the time of SPT inhibition, comparing to SKII (a specific SphK1 inhibitor. Observed changes in insulin signaling proteins were related to the content of specific sphingolipids, namely to the reduction of ceramide. Interestingly, inactivation of SphK1 augmented the effect of PA induced insulin resistance in L6 myotubes, which was associated with further inhibition of insulin stimulated PKB and GSK3β phosphorylation, glucose uptake and the accumulation of sphingosine.

The Pyridoxal 5′-Phosphate (PLP-Dependent Enzyme Serine Palmitoyltransferase (SPT: Effects of the Small Subunits and Insights from Bacterial Mimics of Human hLCB2a HSAN1 Mutations

Directory of Open Access Journals (Sweden)

Ashley E. Beattie

2013-01-01

Full Text Available The pyridoxal 5′-phosphate (PLP-dependent enzyme serine palmitoyltransferase (SPT catalyses the first step of de novo sphingolipid biosynthesis. The core human enzyme is a membrane-bound heterodimer composed of two subunits (hLCB1 and hLCB2a/b, and mutations in both hLCB1 (e.g., C133W and C133Y and hLCB2a (e.g., V359M, G382V, and I504F have been identified in patients with hereditary sensory and autonomic neuropathy type I (HSAN1, an inherited disorder that affects sensory and autonomic neurons. These mutations result in substrate promiscuity, leading to formation of neurotoxic deoxysphingolipids found in affected individuals. Here we measure the activities of the hLCB2a mutants in the presence of ssSPTa and ssSPTb and find that all decrease enzyme activity. High resolution structural data of the homodimeric SPT enzyme from the bacterium Sphingomonas paucimobilis (Sp SPT provides a model to understand the impact of the hLCB2a mutations on the mechanism of SPT. The three human hLCB2a HSAN1 mutations map onto Sp SPT (V246M, G268V, and G385F, and these mutant mimics reveal that the amino acid changes have varying impacts; they perturb the PLP cofactor binding, reduce the affinity for both substrates, decrease the enzyme activity, and, in the most severe case, cause the protein to be expressed in an insoluble form.

In vivo neutron activation at Toronto 1967-1981

International Nuclear Information System (INIS)

Harrison, J.E.; McNeill, K.G.

1986-01-01

Since the inception of work on in vivo neutron activation analysis at Toronto in 1967, the project has grown until these procedures are in routine diagnostic use at the Toronto General Hospital. Approximately 300 calcium tests and 600 nitrogen tests are carried out each year. Cadmium tests are also available. (author)

Phytoplankton and zooplankton data from bottle and nets casts in the coastal North Pacific (180-limit) from the OSHORO MARU by the Faculty of Fisheries/Hokkaido University from 23 April 1967 to 25 April 1967 (NODC Accession 0000503)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Phytoplankton and zooplankton data were collected from the OSHORO MARU in the coastal North Pacific (limit-180) from 23 April 1967 to 25 April 1967. Phytoplankton...

Estimation of alewife biomass in Lake Michigan, 1967-1978

Science.gov (United States)

Hatch, Richard W.; Haack, Paul M.; Brown, Edward H.

1981-01-01

The buildup of salmonid populations in Lake Michigan through annual stockings of hatchery-reared fish may become limited by the quantity of forage fish, mainly alewives Alosa pseudoharengus, available for food. As a part of a continuing examination of salmonid predator-prey relations in Lake Michigan, we traced changes in alewife biomass estimated from bottom-trawl surveys conducted in late October and early November 1967–1978. Weight of adult alewives trawled per 0.5 hectare of bottom (10-minute drag) at 16 depths along eight transects between 1973 and 1977 formed a skewed distribution: 72 of 464 drags caught no alewives; 89 drags caught less than 1 kg; and 2 drags caught more than 100 kg (maximum 159 kg). Analysis of variance in normalized catch per tow indicated highly significant differences between the main effects of years and depths, and highly significant differences in the interactions of years and transects, years and depths, and transects and depths. Five geographic and depth strata, formed by combining parts of transects wherein mean catch rate did not differ significantly, were the basis for calculating annual estimates of adult alewife biomass (with 90% confidence intervals). Estimated biomass of alewives (±90% confidence limits) in Lake Michigan proper (Green Bay and Grand Traverse Bay excluded) rose gradually from 46,000 (±9,000) t in 1967 to 114,000 (±17,000) t in 1973, declined to 45,000 (±8,000) t in 1977, and rose to 77,000 (±19,000) t in 1978.

Should Indonesia Accede to The 1951 Refugee Convention and Its 1967 Protocol?

Directory of Open Access Journals (Sweden)

Dita Liliansa

2015-12-01

Full Text Available Being a non-party to the 1951 Convention relating to the Status of Refugees (“1951 Refugee Convention” and 1967 Protocol relating to the Status of Refugees (“1967 Protocol”, Indonesia does not have legal obligations to provide permanent resettlement for asylum seeker and/or refugee. However, as a transit country for those seeking shelter in Australia, Indonesia undergoes a myriad of issues resulting from illegal entrance by asylum seeker and/or refugee. Besides having neither legal framework nor domestic mechanism to handle asylum seekers and/or refugee, Indonesia’s immigration law identifies every foreigner including asylum seeker and refugee who unlawfully enter Indonesia’s territory into the same box as illegal migrant. It then leads to the arrest of asylum seeker and/or refugee to be put in an over-capacity detention center or other places. This paper will analyze various issues related to asylum seeker and refugee in Indonesia and to weigh whether it is indispensable for Indonesia to accede to the 1951 Refugee Convention and its 1967 Protocol.

Cesium-137 body burden in Japanese from 1967 to 1975

Energy Technology Data Exchange (ETDEWEB)

Anzai, I; Ueda, K; Togo, M [Tokyo Univ. (Japan). Faculty of Medicine

1976-11-01

Cesium-137 concentrations in Japanese male adults were measured monthly during 1967 to 1975 by whole body counting. The /sup 137/Cs content decreased rapidly until 1968, then the reduction rate was considerably decelerated, being probably affected by the French and Chinese nuclear testing. A small rise was observed at the end of 1970, and its causes have been multilaterally studied from the radioecological viewpoints, which has not resulted in a clearcut conclusion. Daily intake estimated from body burden varies in a wide range but, on the average, agrees well with the reported values based on the radiochemical analyses of foods. The integrated absorbed dose from January 1967 to April 1975 is calculated to be 2.5 mrads. The authors re-emphasize the importance of the periodic measurement of human population.

Annual Report to Congress of the Atomic Energy Commission for 1967

Energy Technology Data Exchange (ETDEWEB)

Seaborg, Glenn T.

1968-01-31

The document represents the 1967 Annual Report of the Atomic Energy Commission (AEC) to Congress. The report opens with a Summary of Atomic Energy Programs in 1967 and includes 17 Chapters, 11 appendices and an index. Chapters are as follows: (1) Source and Special Nuclear Materials; (2) Safeguards and Materials Management; (3) The Nuclear Defense Effort; (4) Naval Propulsion Reactors; (5) Reactor Development and Technology; (6) Licensing and Regulating the Atom; (7) Operational Safety; (8) Nuclear Rocket Propulsion; (9) Specialized Nuclear Power Units; (10) Isotopic Radiation Applications; (11) The Plowshare Program; (12) International Cooperation Activities; (13) Informational Activities; (14) Nuclear Education and Training; (15) Basic Research; (16) Industrial Participation Aspects; and, (17) Administrative and Management Matters.

A política bancária do regime militar: o projeto de conglomerado (1967-1973 The finance policy of military regime: the conglomerate project (1967-1973

Directory of Open Access Journals (Sweden)

José Pedro Macarini

2007-12-01

Full Text Available Este artigo examina a política bancária e financeira conduzida por Delfim Netto de 1967 a 1973, a qual se revestiu de características específicas. São examinadas as pronunciadas tendências à concentração no segmento dos bancos comerciais privados e a sua expansão para outras faixas de operação, formando conglomerados financeiros e, assim, alterando profundamente a estrutura projetada originalmente pela reforma de 1964. Ambos os processos estiveram vinculados à orientação particular da política econômica a partir de 1967, cujo sentido maior encontrou expressão na tentativa de implementar, no governo Médici, um projeto de conglomerado integrando banco e indústria, visando a consolidar um segmento de grandes empresas privadas nacionais. O artigo sistematiza evidência disponível acerca desse projeto estratégico - um capítulo importante da política econômica durante uma fase do regime militar.This article discusses the banking policy led by Delfim Netto from 1967 trough 1973, which had special features. It is examined the tendency to banking concentration, very intense in those years, as well as the acute centralization process which led to the constitution of financial conglomerates, thus transforming the financial structure in a way not foreseen by the banking and financial reforms of 1964. Both processes reflected the new course of economic policy since 1967, having as its major objective to induce the formation of a new form of private capitalist organization - the conglomerate, integrating banking and industry -, which would led to the consolidation of a segment of big national private firms. The article seeks to collect the available evidence about that strategic project developed during a phase of the military regime.

On the validity of discocyclina ramaraoi Samanta n.sp. 1967

Digital Repository Service at National Institute of Oceanography (India)

Setty, M.G.A

@iDiscocyclina ramaraoi@@ described as a new species by Samanta in 1967 from the Discocyclinid limestone-Upper Marlstone of Pondichery formation (Upper Palaeocene-Lower Eocene) of South India is compared with @iD. boetonensis@@ (van der Vlerk...

Estadísticas culturales de Colombia: abril de 1967

Directory of Open Access Journals (Sweden)

Fernán Torres León

1967-04-01

Full Text Available El documento presenta un cuadro comparativo de las actividades culturales del pais, así como las exposiciones de artes plasticas y otras inauguradas, recitales poéticos, conciertos y recitales de música, libros de autores colombianos publicados y representaciones teatrales realizadas en el pais en el mes de abril de 1967

Operation and maintenance of the RA reactor, Report on operation in 1967, task 7.08; Pogon i odrzavanje reaktora RA, Izvestaj o radu u 1967. god. Zadtak 7.08

Energy Technology Data Exchange (ETDEWEB)

Milosevic, D and others [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Yugoslavia)

1967-12-15

During 1967, RA reactor was operated at nominal power for 190 days and 23 days at lower power levels. The total production was 31060 MWh. Report contains data until Dec. 22. 1967, but the reactor was planned to operate three more full days at nominal power of 6.5 MW, meaning that the total number of operation at full power would be 193 days ant the total production would be 30625 which is 2% higher than planned. Practically there were no discrepancies from the plan. There have been 5 shorter interruptions in operation caused by demand of the experiment, minor repairs and thunderstorm. Only one longer interruption was caused by difficulties in secondary water supply. The reactor was used for irradiation and experiments according to the demand of 590 users, of which 470 were from the Institute. This report contains detailed data about reactor power and experiments performed in 1967, and a chart showing discrepancies from the plan. Data concerned about the utilization of reactor experimental channels are included as well. Total number of safety shutdowns was 19, of which 11 were caused by power cuts, 6 due to voltage instabilities, and 2 due to failures of instrumentation. These data are compared to safety shutdown data from 1962 - 1967. There have been no accidents which could cause any significant effects. The only important incident occurred this year was caused by leaking of sulphur from an experimental capsule. It is described in detail. Detailed data concerning exposure of the personnel are part of this report. In spite of the fact that this year the spent fuel was for the first time packed and mixing of the fuel in the core there have been no unplanned difficulties nor contaminations.

Evaluation of radiological exposure from Plowshare applications, 1967--1975

International Nuclear Information System (INIS)

Barton, C.J.; Kaye, S.V.

1975-08-01

A review of the highlights and accomplishments of the nine-year program, FY 1967-75, at ORNL on the evaluation of the radiological exposure from Plowshare applications is presented. Conclusions based on the studies summarized are given. Chronological lists of presentations, reports and open literature publications on the various investigations of the program are appended to the report. (auth)

Strontium-90 content of human bone collected in 1967

International Nuclear Information System (INIS)

Jeanmaire, L.; Patti, F.

1969-01-01

This report follows report CEA-R-3381 and presents the strontium 90 content of human bones collected in 1967 in the Paris area. The main trend is much the same as during 1966; contamination levels are falling down in infants up to 5 year old. Beyond this age, the values are the same or experience a slight increase. (authors) [fr

47 CFR 0.417 - The Annual Reports.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false The Annual Reports. 0.417 Section 0.417 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION General Information Printed... of developments during the year, and selected industry statistics. [32 FR 10571, July 19, 1967] ...

Transformation Deja Vu? A Comparison of Military Improvements of Israel (1967-1973) and the United States (1990-2002)

Science.gov (United States)

2002-09-06

Transformation Déjà Vu ? A Comparison of Military Improvements of Israel (1967-1973) and the United States (1990-2002) Major William A. Forkner, USAF...Transformation Déjà Vu ? A Comparison of Military Improvements of Israel (1967-1973) and the United States (1990-2002) 5a. CONTRACT NUMBER 5b. GRANT NUMBER

El "régimen dual" en Israel desde 1967

Directory of Open Access Journals (Sweden)

Lev Grinberg

2008-01-01

Full Text Available Este artículo aborda el establecimiento del peculiar régimen de dominación dual de Israel desde 1967, argumentando que la estructura de este régimen convierte a las élites militares en un actor político crucial. El régimen dual se basa en la separación geográfi ca entre dos regímenes diferentes de control y legitimación. Argumentaré aquí que la guerra de 1967 fue un parteaguas histórico, ya que acarreó un desdibujamiento de las fronteras israelíes y la llegada de un régimen dual que legitima la división del poder político entre las élites militares y civiles que gobiernan Israel-Palestina. Mi objetivo es mostrar las contradicciones inherentes de este régimen dual de “ocupación democrática” y así arrojar luz sobre la dinámica de los espacios políticos de acuerdo a la población ocupada: su apertura, por reconocimiento y negociación, y su cancelación, por el uso de la violencia.

TREN PEMIKIRAN INTELEKTUAL MUSLIM KONTEMPORER DI TIMUR TENGAH PASCA-DIFITISME 1967

Directory of Open Access Journals (Sweden)

Yoyo Yoyo

2012-12-01

Full Text Available This article is an effort to make a clear map on contemporary Muslim intellectuals in the Middle East after the Arab defeat in 1967. The Six-Day War took place in June 1967 was a disaster for the Arab world. It ended the ideology of Pan-Arab nationalism and encouraged the rise of four compating self-criticism ideologies: Marxism, Liberalism, Fundamentalism and Nationalism. The four ideologies have their own particular responses and solutions to the Arab crisis. The result of this research shows that Islamic fundamentalism is still the strongest ideology compared to the secular ideologies. The Arab Spring in 2011 proved the fact and paved a way for the Islmists to become dominant in the political arena, as recently shown in Egypt. The other Islamist militant groups, such as Jama’ah Islamiyyah are now more free to promote the implementation of Islamic syari’ah.

A genetic screen for increasing metabolic flux in the isoprenoid pathway of Saccharomyces cerevisiae: Isolation of SPT15 mutants using the screen

Directory of Open Access Journals (Sweden)

M. Wadhwa

2016-12-01

Full Text Available A genetic screen to identify mutants that can increase flux in the isoprenoid pathway of yeast has been lacking. We describe a carotenoid-based visual screen built with the core carotenogenic enzymes from the red yeast Rhodosporidium toruloides. Enzymes from this yeast displayed the required, higher capacity in the carotenoid pathway. The development also included the identification of the metabolic bottlenecks, primarily phytoene dehydrogenase, that was subjected to a directed evolution strategy to yield more active mutants. To further limit phytoene pools, a less efficient version of GGPP synthase was employed. The screen was validated with a known flux increasing gene, tHMG1. New mutants in the TATA binding protein SPT15 were isolated using this screen that increased the yield of carotenoids, and an alternate isoprenoid, α-Farnesene confirming increase in overall flux. The findings indicate the presence of previously unknown links to the isoprenoid pathway that can be uncovered using this screen. Keywords: Metabolic engineering, Carotenoids, Isoprenoids, α-Farnesene, Rhodosporidium toruloides, SPT15

Hanford atmospheric dispersion data: 1960 through June 1967

Energy Technology Data Exchange (ETDEWEB)

Nickola, P.W.; Ramsdell, J.V.; Glantz, C.S.; Kerns, R.E.

1983-11-01

This volume presents dispersion and supporting meteorological data from experiments conducted over relatively flat terrain at Hanford, Washington from January 1960 through June 1967. The nature of the experiments, the sampling grids, and the tracer techniques used are described in the narrative portion of the document. Appendices contain the time-integrated concentrations for samplers within the plumes, summaries of the concentration distributions across the plumes, and wind and temperature profile data for each release period. 18 references, 7 figures, 3 tables.

Analysis of U.S. household wood energy consumption: 1967-2009

Science.gov (United States)

Nianfu. Song; Francisco X. Aguilar; Stephen R. Shifley; Michael E. Goerndt

2012-01-01

The residential sector consumes about 23% of the energy derived from wood (wood energy) in the U.S. An estimated error correction model with data from 1967 to 2009 suggests that residential wood energy consumption has declined by an average 3% per year in response to technological progress, urbanization, accessibility of non-wood energy, and other factors associated...

31 CFR 342.0 - Offering of notes.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Offering of notes. 342.0 Section 342.0 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE... or greater denomination. This offering was effective from May 1, 1967 until the close of business...

Understanding long-term (1982-2013) patterns and trends in winter wheat spring green-up date over the North China Plain

Science.gov (United States)

Wang, Sisi; Mo, Xingguo; Liu, Zhengjia; Baig, Muhammad Hasan Ali; Chi, Wenfeng

2017-05-01

Monitoring the spring green-up date (GUD) has grown in importance for crop management and food security. However, most satellite-based GUD models are associated with a high degree of uncertainty when applied to croplands. In this study, we introduced an improved GUD algorithm to extract GUD data for 32 years (1982-2013) for the winter wheat croplands on the North China Plain (NCP), using the third-generation normalized difference vegetation index form Global Inventory Modeling and Mapping Studies (GIMMS3g NDVI). The spatial and temporal variations in GUD with the effects of the pre-season climate and soil moisture conditions on GUD were comprehensively investigated. Our results showed that a higher correlation coefficient (r = 0.44, p the improved algorithm relative to GUD from the MCD12Q2 phenology product. In spatial terms, GUD increased from the southwest (less than day of year (DOY) 60) to the northeast (more than DOY 90) of the NCP, which corresponded to spatial reductions in temperature and precipitation. GUD advanced in most (78%) of the winter wheat area on the NCP, with significant advances in 37.8% of the area (p the interannual scale, the average GUD advanced from DOY 76.9 in the 1980s (average 1982-1989) to DOY 73.2 in the 1990s (average 1991-1999), and to DOY 70.3 after 2000 (average 2000-2013), indicating an average advance of 1.8 days/decade (r = 0.35, p the pre-season temperature, our findings underline that the effect of the pre-season soil moisture on GUD should also be considered. The improved GUD algorithm and satellite-based long-term GUD data are helpful for improving the representation of GUD in terrestrial ecosystem models and enhancing crop management efficiency.

Trend of suspended sediment load in the Velika Morava River in the period 1967-2007

Directory of Open Access Journals (Sweden)

Mustafić Sanja

2014-01-01

Full Text Available The paper is concerned with identifying changes in the time series of discharge (Q, suspended sediment concentration (SSC and sediment load (Qs of the Velika Morva River. The catchment area on farthest hydrological profile Ljubičevski most on Velika Morava River is approximately 35,496 km2. In this profile were carried out daily measurements of flow and concetration of silt in the period from 1967 to 2007. Average perennial transport of suspended sediment is 2.57ˣ106 t (72.4 t/km2/yr and ranged from 0.17ˣ106 t (4.8 t/km2/yr to 10.02ˣ106 t (282.2 t/km2/yr. Trends determined for Q, SSC and Qs are statistically obtained using the non-parametric Mann-Kendall test. Results of Mann-Kendall test show that Q has a slight declining trend of annual values which do not show statistical significance. Decline in trendline SSC and Qs is a significant at the level of 0.01. Calculating the standardized regression coefficients, it was found that the relative impact of SSC on sediment load is 3.1 time higher than the impact of discharge. From 1967 to 2007 the average decrease in sediment load at the mouth of the Velika Morava into the Danube was 3.1 t/km2/yr. [Projekat Ministarstva nauke Republike Srbije, br. 43007: The Research on Climate Change Influences on Environment: Influence Monitoring, Adaptation and Mitigation, subproject No. 9: Torrential Floods Frequency, Soil and Water Degradation as the Consequence of Global Changes

Reconsidering Glenn Gould’s 1967 Radio Montage ”The Idea of North”

DEFF Research Database (Denmark)

Sørensen, Bent

, philosophers.” Gould’s work is a strikingly original investigation into the identity repercussions of isolation and northern exposure upon five carefully selected Canadians, recorded in the year of the Canadian centennial, 1967. My paper will examine the piece from a cultural studies approach, discussing both...

STELLAR MASSES AND STAR FORMATION RATES OF LENSED, DUSTY, STAR-FORMING GALAXIES FROM THE SPT SURVEY

Energy Technology Data Exchange (ETDEWEB)

Ma, Jingzhe; Gonzalez, Anthony H. [Department of Astronomy, University of Florida, Gainesville, FL 32611 (United States); Spilker, J. S.; Marrone, D. P. [Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States); Strandet, M. [Max-Planck-Institut für Radioastronomie, Auf dem Hügel 69 D-53121 Bonn (Germany); Ashby, M. L. N. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Aravena, M. [Núcleo de Astronomía, Facultad de Ingeniería, Universidad Diego Portales, Av. Ejército 441, Santiago (Chile); Béthermin, M.; Breuck, C. de; Gullberg, B. [European Southern Observatory, Karl Schwarzschild Straße 2, D-85748 Garching (Germany); Bothwell, M. S. [Cavendish Laboratory, University of Cambridge, JJ Thompson Avenue, Cambridge CB3 0HA (United Kingdom); Brodwin, M. [Department of Physics and Astronomy, University of Missouri, 5110 Rockhill Road, Kansas City, MO 64110 (United States); Chapman, S. C. [Dalhousie University, Halifax, Nova Scotia (Canada); Fassnacht, C. D. [Department of Physics, University of California, One Shields Avenue, Davis, CA 95616 (United States); Greve, T. R. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Hezaveh, Y. [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Stanford, CA 94305 (United States); Malkan, M. [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1547 (United States); Saliwanchik, B. R., E-mail: jingzhema@ufl.edu [Department of Physics, Case Western Reserve University, Cleveland, OH 44106 (United States); and others

2015-10-10

To understand cosmic mass assembly in the universe at early epochs, we primarily rely on measurements of the stellar masses and star formation rates (SFRs) of distant galaxies. In this paper, we present stellar masses and SFRs of six high-redshift (2.8 ≤ z ≤ 5.7) dusty, star-forming galaxies (DSFGs) that are strongly gravitationally lensed by foreground galaxies. These sources were first discovered by the South Pole Telescope (SPT) at millimeter wavelengths and all have spectroscopic redshifts and robust lens models derived from Atacama Large Millimeter/submillimeter Array observations. We have conducted follow-up observations to obtain multi-wavelength imaging data using the Hubble Space Telescope (HST), Spitzer, Herschel, and the Atacama Pathfinder EXperiment. We use the high-resolution HST/Wide Field Camera 3 images to disentangle the background source from the foreground lens in Spitzer/IRAC data. The detections and upper limits provide important constraints on the spectral energy distributions (SEDs) for these DSFGs, yielding stellar masses, IR luminosities, and SFRs. The SED fits of six SPT sources show that the intrinsic stellar masses span a range more than one order of magnitude with a median value ∼5 ×10{sup 10} M{sub ⊙}. The intrinsic IR luminosities range from 4 × 10{sup 12} L{sub ⊙} to 4 × 10{sup 13} L{sub ⊙}. They all have prodigious intrinsic SFRs of 510–4800 M{sub ⊙} yr{sup −1}. Compared to the star-forming main sequence (MS), these six DSFGs have specific SFRs that all lie above the MS, including two galaxies that are a factor of 10 higher than the MS. Our results suggest that we are witnessing ongoing strong starburst events that may be driven by major mergers.

Barcelona's water supply, 1867–1967 : the transition to a modern system

OpenAIRE

Guàrdia Bassols, Manuel; Rosselló i Nicolau, Maribel; Garriga Bosch, Sergi

2013-01-01

Barcelona's water supply since 14th century to 1867, the Eixample's water supply problem the development of modern water supply since 1867 to 1967 the new sanitation system impact on water consumption water's slow entry into the domestic sphere from post-war restrictions to widespread water consumption. Peer Reviewed

The 1967 Arab-Israeli Six-Day War: An Analysis Using the Principles of War

National Research Council Canada - National Science Library

Glazer, Thomas

2001-01-01

The 1967 Arab-Israeli Six-Day War provides the operational commander with an excellent opportunity to examine the importance of the application, or misapplication, of the principles of war in a conflict...

ANÁLISE DE PERFIS DE SONDAGEM SPT E CARACTERIZAÇÃO GEOTÉCNICA DE SOLOS DO MUNICÍPIO DE NATAL

Directory of Open Access Journals (Sweden)

Kadson Ranniere da Rocha Câmara

2007-12-01

Full Text Available O presente trabalho tem como objetivo a caracterização geotécnica de solos do município de Natal para fins de obtenção de parâmetros de resistência ao cisalhamento e de deformabilidade do material. Quatro zonas foram definidas para a compilação de resultados de relatórios de sondagens tipo SPT (Standard Penetration Test, buscando-se destacar aspectos que diferenciem geotecnicamente as zonas consideradas. Campanhas de ensaios de laboratório foram relizadas para a idendificação de características geotécnicas (perfil de umidades e granulometria, densidade das partículas e deformabilidade de solo definido como referência para as análises. Parâmetros de resistência ao cisalhamento e de deformabilidade dos solos encontrados foram determinados mediante emprego de equações empíricas. Os resultados encontrados indicam haver importante variabilidade nas propriedades geotécnicas dos solos analisados, tanto para solos pertencentes a uma mesma zona como para solos de zonas distintas. O posicionamento das unidades geotécnicas e o estado de compacidade das mesmas consistem em variáveis destacadas no estudo realizado. Palavras-chaves: Mecânica dos Solos; Ensaios In Situ; Perfis SPT; Caracterização Geotécnica.

Angry young architects : Counterculture and the critique of modernism in Brisbane, 1967-72

NARCIS (Netherlands)

Gosseye, J.

2014-01-01

By 1967, Brisbane architecture students had had enough. Disenchantment with their “out-dated” architectural education and the rigidity of the Australian architectural establishment opened out onto the wider context of the Moratorium opposing the Vietnam War, and the peculiarly conservative and

Cumulative Index of ERIC Resources in Counseling and Personnel Services. 1967-1976.

Science.gov (United States)

Walz, Garry R.; And Others

This cumulative index contains over 5500 titles from the ERIC collection, and represents all the document input from the Clearinghouse on Counseling and Personnel Services between 1967-1976. Topics cover theoretical and practical information in all areas of counseling and guidance as well as in drug abuse, aging, sexuality and death. Directions…

The Family Gap in Pay: New Evidence for 1967 to 2013

Directory of Open Access Journals (Sweden)

Ipshita Pal

2016-08-01

Full Text Available This paper provides new evidence on the family gap in pay—the differential in hourly wages between women with children and women without children—between 1967 and 2013, five decades that include important changes in women's employment, especially mothers’ employment, policy reforms as well as contrasting economic cycles. We use data from the Current Population Survey and adjust for selection into motherhood, by estimating ordinary least square models and (as a robustness check applying augmented inverse probability of treatment weighting, using the standard doubly robust estimator. For women overall, we find a decline in the family gap over this period from 6 percent in 1967 and 1968 to about 1 percent in 2011 through 2013. However, results vary by marital status, education, race-ethnicity, immigration status, temporal flexibility, and occupation. The most striking difference we find is between mothers who are married and those who are not. The family gap declined for married mothers and was replaced by a positive wage differential in the most recent period, whereas for unmarried mothers, a wage gap persisted throughout the two decades, rising to a notable high of 10 percent in 1996 through 1998.

Developments and trends in soil science: 100 volumes of Geoderma (1967-2001)

NARCIS (Netherlands)

Hartemink, A.E.; McBratney, A.B.; Cattle, J.A.

2001-01-01

Between September 1967 and March 2001, Geoderma published 100 volumes containing 2079 papers covering 31,637 pages and filling 191 cm of shelf space. No doubt that is a lot of paper, but what is in it? This paper starts with a brief history of the journal and an overview of editors and a geographic

Evolution of caesium 137 levels in coconut water and copra in french Polynesia, since 1967

International Nuclear Information System (INIS)

Kabis de Saint-Chamas, L.; Bablet, J.P.; Ducousso, R.; Arnould, C.

1991-01-01

Nuclear experiments have been carried out by France in french Polynesia since 1966. The tests were first atmospheric, they have been underground since 1975. The experiment monitoring programme includes monitoring of 137 Cs contents in coconuts from the whole french polynesian territory. The methodology is described and the results of the 2 589 samples collected for 1967 to 1988 are presented. The maximum content found since 1967 is 52 Bq.kg -1 for coconut water and 289 Bq.kg -1 for coconut copra. The decrease of 137 Cs content is constant without discontinuity, whatever the distance from the explosion sites. The committed dose equivalent from 137 Cs delivered by coconut water and copra consumption represents only a few microsieverts a year [fr

United States-Vietnam Relations 1945-1967. Book 7 of 12

Science.gov (United States)

1971-09-20

1967," we are trans - mitting herewith for your use four sets of the declassified study. You will note that the declassified review contains 43...line with above you should make i-t emphatically clear whenever useful, that we do not believe a Phat/ Duc government can effectively govern the...for such support. In his reaction to • the PROVN Report in May 1966, in his directives to advisers around the time of the Chinh -Hunnicutt affair in

The strategic and political consequences of the June 1967 war

OpenAIRE

Machairas, Dimitrios

2017-01-01

This article analyses the direct, relatively immediate strategic and political consequences of the 1967 Arab-Israeli War, focusing on Israel’s post-war security situation, the connection of the Six-Day War with the next episodes of the Arab-Israeli conflict, and on important and relevant to the issue political realities emerging in the affected societies, such as the Palestinian national movement and refugee problem, the rise of Islam, and the Jewish colonisation of the occupied territories. ...

El Movimiento estudiantil chileno y el proceso de reforma universitaria, 1967-1968

DEFF Research Database (Denmark)

Cancino, Hugo

2012-01-01

En la presente ponencia analizamos el contexto histórico y cultural del movimiento de reforma de la Universidad de Chile, 1967-68 y su gestación en la Facultad de Filosofía y Educación. Este movimiento que se inscribió en la dilatada tradición de lucha de los estudiantes chilenos y latinoamericanos...

1967 radiation accident near Pittsburgh, Pennsylvania, and a follow-up report

International Nuclear Information System (INIS)

Gilberti, M.V.

1980-01-01

On 4 October 1967, three technicians were simultaneously accidentally exposed to whole-body radiation from a Van de Graaff linear accelerator. The accelerator generated electrons down a tube at a target of gold, where a steady stream of x-rays was produced. The clinical course, treatment of the acute and chronic changes, and the current health status of the three patients serve as the basis of this report

The Mini-SPT (Space Particle Telescope) for dual use: Precision flux measurement of low energy proton electron and heavy ion with tracking capability and A compact, low-cost realtime local radiation hazard/alarm detector to be used on board a satellite

Science.gov (United States)

Alpat, Behcet; Ergin, Tulun; Kalemci, Emrah

2016-07-01

The Mini-SPT project is the first, and most important, step towards the ambitious goal of creating a low-cost, compact, radiation hardened and high performance space particle telescope that can be mounted, in the near future, as standard particle detector on any satellite. Mini-SPT will be capable of providing high quality physics data on local space environment. In particular high precision flux measurement and tracking of low energy protons and electrons on different orbits with same instrumentation is of paramount importance for studies as geomagnetically trapped fluxes and space weather dynamics, dark matter search, low energy proton anisotropy and its effects on ICs as well as the solar protons studies. In addition, it will provide real-time "differentiable warnings" about the local space radiation hazard to other electronics systems on board the hosting satellite, including different criticality levels and alarm signals to activate mitigation techniques whenever this is strictly necessary to protect them from temporary/permanent failures. A real-time warning system will help satellite subsystems to save significant amount of power and memory with respect to other conventional techniques where the "mitigation" solutions are required to be active during entire mission life. The Mini-SPT will combine the use of technologies developed in cutting-edge high energy physics experiments (including technology from CMS experiments at CERN) and the development of new charged particle detecting systems for their use for the first time in space. The Mini-SPT essential objective is, by using for the first time in space SIPMs (Silicon Photomultipliers) technology for TOF and energy measurements, the production of high quality data with a good time, position and energy resolutions. The mini-SPT will consists of three main sub-units: a- A tracking and dE/dX measuring sub-detector which will be based on silicon pixel detectors (SPD) coupled to the rad-hard chip ROC-DIG (Read

A Longitudinal Study of Illinois State Scholarship Commission Monetary Award Recipients, 1967-1974.

Science.gov (United States)

Boyd, Joseph D.; Fenske, Robert H.

The present effectiveness and future direction of monetary award programs administered by the Illinois State Scholarship Commission is examined in three surveys. A random sample of 1,000 was drawn from the total number of scholarship recipients during the 1967-68 and 1970-71 academic years; 2,000 from the 1973-74 survey. It is shown that: (1)…

Resources on Campus Governance and Employment Relations, 1967-1977. With Essay, Annotations, and Indexes.

Science.gov (United States)

Tice, Terrence N.

An annotated bibliography containing 1,110 items from 1967 through early 1977 and other relevant resources covers virtually all the significant material on campus collective bargaining and closely related issues regarding campus governance and employment relations. It complements five publications from 1972-76 and indexes both authors and…

National Catholic Educational Association: 90 Years, 1904-1994. Meeting Crisis with Confidence (1967-1974).

Science.gov (United States)

Koob, C. Albert

1994-01-01

Describes the author's experiences and challenges as president of the National Catholic Educational Association between 1967-74, including the challenges of Vatican II and new developments in education. Indicates that the period, which began in financial and educational crisis, was a period of professional improvement in Catholic education. (MAB)

Argentina 1967-70. Un tentativo fallito di stabilizzazione.

Directory of Open Access Journals (Sweden)

G. MAYNARD

2014-08-01

Full Text Available Between 1950 and 1966 prices in Argentina rose at an average annual rate exceeding 25 percent. There have been several attempts to stabilise the situation, notably in 1966 when the military government took command. This attempt appeared to have considerable initial success, however, by 1970 the inflation rate began to accelerate again. This article describes the nature and characteristics of the stabilisation policy pursued in 1967-69. The author explains why, despite its initial success, in the end it broke down. Implications for the structuralist-monetarist controversy are then drawn. Finally, some conclusions that can be drawn for long-run development strategy and short-run stabilisation policy in Argentina are suggested.JEL: E31, E52, E60

Affect and Cultural Change: The Rise of Popular Zionism in the British Jewish Community After the Six Day War (1967)

OpenAIRE

Hakim, Jamie

2012-01-01

In current Jewish Studies scholarship there is a broad consensus that the Arab-Israeli war of June 1967 caused both an intense emotional response in Britain’s Jewish community and a change in the relationship this community had with the State of Israel. What this scholarship has yet to provide is either a detailed account of the ways that the June 1967 war impacted on this community or a sustained theorisation of how the intensity generated by a world-historical event might bring about change...

La dictature des colonels en Grèce, 1967-1974 The colonel’s dictatorship in Greece, 1967-1974, geostrategical stakes

Directory of Open Access Journals (Sweden)

Corinne Talon

2012-12-01

Full Text Available L’analyse de la dictature des colonels grecs (1967-74 vue par 3 quotidiens français révèle, par ses divergences, les orientations de la presse française.Il s’agit de présenter dans cet article, les enjeux géostratégiques de la dictature des colonels en Grèce, de montrer si ce régime, en Méditerranée, durant la guerre froide, présentait un intérêt pour les États-Unis, et ceci, à travers les analyses de trois quotidiens nationaux français : Le Monde, Le Figaro et L’Humanité. Cet article s’articule autour de trois périodes. La première, 1967, présente la thèse officielle du régime : la mise en place de la dictature en raison d’une menace communiste imminente. Cette partie montre la divergence d’analyse des trois journaux sur cette thèse, mais aussi, sur le rôle des États-Unis. La deuxième période se concentre sur les années 1968 à 1973 et montre les points de vue sur l’existence d’une protection américaine du régime. Si pour les trois journaux, les États-Unis soutiennent le régime pour des raisons géostratégiques, en revanche, pour Le Monde et l’Humanité, cette protection va au-delà, car elle permet au régime de se maintenir. Enfin, la troisième partie traite de l’année 1974, du coup d’État manqué à Chypre, de la chute de la dictature, et là encore, du rôle, voire de la responsabilité des États-Unis. Ces divergences, convergences ou nuances d’appréciations constituent une somme d’interrogation et de recherches.The purpose of this article is to present the geostrategical stakes of the colonels’ dictatorship in Greece, through the analysis of three French national daily newspaper: Le Monde, L’Humanité and Le Figaro. It will show whether or not this regime, in the Mediterranean, during the cold war, represented an interest for the US. This article turns around three periods. The first, 1967, presents the regime’s official standpoint: the establishment of the

Baby Booming Inequality? Demographic Change and Inequality in Norway, 1967{2004.

OpenAIRE

Almås, Ingvild; Havnes, Tarjei; Mogstad, Magne

2011-01-01

We demonstrate how age-adjusted inequality measures can be used to evaluate whether changes in inequality over time are because of changes in the age structure. In particular, we explore the hypothesis that the substantial rise in earnings inequality since the early 1980s is driven by the large baby boom cohorts approaching the peak of the age-earnings profile. Using administrative data on earnings for every Norwegian male over the period 1967-2004, we find that the impact of age ...

Stability of a sweet product of tamarillo (Cyphomandra betacea preserved by combined methods

Directory of Open Access Journals (Sweden)

Villegas-Ruíz Xadeni

2013-06-01

Full Text Available The aim of this study was the use of the hurdle technology for preparing a sweet product (SPT of tamarillo (Cyphomandra betacea and assess its storage stability. SPT was prepared at the fruit natural pH (3.72, lowering the water activity (aw (0.901 by adding sucrose and sodium benzoate (0.1% as antimicrobial. SPT was stored under refrigeration (4 °C conditions protected from light and it was analyzed every third day for 60 days. Physicochemical (color, aw, pH, and titratable acidity as citric acid, antioxidant (antioxidant capacity, total phenolics, and anthocyanins, and microbiological (aerobic mesophilic bacteria, molds, and yeasts, were determined. SPT was mixed with plain yogurt to evaluate the overall sensory acceptance during storage. The evaluation took place every seventh day during 49 days. The storage time had no effect neither on aw, pH or acidity of the SPT. It was observed an increase in the net change of color (0 to 4.9 and a decrease in total phenolic compounds (1.213-0.816 mg gallic acid/g SPT, total monomeric anthocyanins (0.910-0.611 mg cyanidin-3-glucoside/g SPT g, and antioxidant capacity (5.816-3.576 µmole Trolox/g SPT. The aerobic mesophilic bacteria ( 0.05 during storage.

Educación superior en Chile : instituciones, mercados y políticas gubernamentales, 1967-2007

NARCIS (Netherlands)

Brunner Ried, José Joaquín

2008-01-01

This dissertation provides a detailed analysis of the Chilean higher education system and policies over the period 1967-2007. It focuses on the creation, development and working of higher education markets and policies. The approach employed is shared with other recent specialized market studies of

A Gift or a Waste? Quintavalle, Surplus Embryos and the Abortion Act 1967.

Science.gov (United States)

Cherkassky, Lisa

2017-07-01

The destruction of an embryo must be justified in law. This is to prevent frivolous wastage and to show the respect afforded by the Warnock Report (1984). For example, embryonic destruction during pregnancy is underpinned by the Abortion Act 1967, and embryonic destruction during fertility treatment is regulated by the Human Fertilisation and Embryology Act 1990. However, following the appeal decision in R (Quintavalle) v Human Fertilisation and Embryology Authority (and Secretary of State for Health) [2005] 2 A.C. 561, embryos can now be created for a bone marrow tissue match to a sick sibling under the Human Fertility and Embryology Act 1990 according to the subjective desires of the mother. This opens the door to the first example of embryonic destruction on unique social-eugenic grounds with no clear lawful justification. It is argued that these embryos should be afforded a unique destruction provision under an amended version of section 1(1)(a) of the Abortion Act 1967 in light of their 'social-eugenic' nature. This would protect the Human Fertilisation and Embryology Authority from accusations of undercover eugenic practices and reinstate the respect shown towards embryos in law.

Geologic map of metallic and nonmetallic mineral deposits, Badakhshan Province, Afghanistan, modified from the 1967 original map compilation of G.G. Semenov and others

Science.gov (United States)

Peters, Stephen G.; Stettner, Will R.; Mathieux, Donald P.; Masonic, Linda M.; Moran, Thomas W.

2014-01-01

This geologic map of central Badakhshan Province, Afghanistan, is a combined, redrafted, and modified version of the Geological map of central Badakhshan, scale 1:200,000 (sheet 217), and Map of minerals of central Badakhshan, scale 1:200,000 (also sheet 217) from Semenov and others (1967) (Soviet report no. R0815). That unpublished Soviet report contains the original maps and cross sections, which were prepared in cooperation with the Ministry of Mines and Industries of the Republic of Afghanistan in 1967 under contract no. 1378 (Technoexport, USSR). This USGS publication also includes the gold metallogeny summarized in Abdullah and others (1977) and Peters and others (2007, 2011), and additional compilations from Guguev and others (1967).

Svangerskapskomplikasjoner og risikoen for astma blant nordmenn født 1967-1993

Directory of Open Access Journals (Sweden)

Per Nafstad

2009-10-01

Full Text Available Bakgrunn  Metode  Resultater  Konklusjon  Background  : Fetal life events may affect the development of the immune and/or respiratory system and increase the risk of asthma and allergic diseases. The objective of this study was to test the hypothesis that pregnancy complications are associated with the risk of developing asthma in the offspring.Methods  : The study population comprised Norwegian live births 1967-1993 (n = 1 548 429 linking the Medical Birth Registry of Norway (MBRN (exposure variables and the National Insurance Administration Register (NIAR (outcome variables, which covers all Norwegians. The MBRN variables included pregnancy complications, pregnancy outcomes and diseases of the mother. The NIAR provided data on all Norwegians who had received cash benefit for treatment of asthma from 1967 to 1996 (n = 5938, 3.9/1000 persons.Results  : In multiple logistic regression analysis, pregnancy complications (International Classification of Diseases (ICD-8 codes: 630-34 were associated with the risk of asthma (odds ratio 1.82, 95% confidence interval: 1.67–1.98. This was also the case if analyses were performed in different strata according to year of birth, plurality, maternal atopy, geographical district of birth, and maternal education.Conclusions  : Pregnancy complications may represent risk factors for the development of asthma in the offspring or express early signs of increased risk for developing the disease.: Svangerskapskomplikasjoner hos mor kan gi økt risiko for utvikling av astma hos barnet eller utrykke tidlige tegn på økt risiko for å utvikle sykdommen: Multipell logistisk regresjonsanalyse viste at svangerskapskomplikasjoner (International Classification of Diseases (ICD-8 kode 630-34 var assosiert med risikoen for å ha fått grunn- og/eller hjelpestønad for astma (odds ratio 1,82, 95% konfidensintervall: 1,67–1,98. Dette var også tilfelle hvis analysene ble utført i forskjellige strata av f

Exploring the secret history of the legal service of the European Executives, 1952-1967

DEFF Research Database (Denmark)

Rasmussen, Morten

key private archives, consequently constitutes the first attempt to write a history of the legal service of the European executives from 1952 to 1967. With the functions and actions of the legal service being very far from the public spotlight, the story presented here has until now been completely...... to finally be able to affirm, reject or nuance Stein’s classic claim....

Multiple connections in European co-operation: : international organizations, policy ideas, practices and transfers 1967–92

NARCIS (Netherlands)

Kaiser, Wolfram; Patel, Kiran Klaus

2017-01-01

International organizations are ubiquitous in contemporary Europe and the wider world. This special issue takes a historical approach to exploring their relations with each other in Western Europe between 1967 and 1992. The authors seek to ‘provincialize’ and ‘de-centre’ the European Union’s role,

Twenty Years Wandering (But Not in the Desert: Brazil’s 1967-1989 absence from UN peacekeeping

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Eduardo Uziel

2015-03-01

Full Text Available Since the early 1990s, Brazilian officials have often underlined the country’s role as a traditional contributor of troops to peacekeeping operations, beginning with participation in UNEF I, in 1957. However, for the two decades from 1967 to 1989, Brazil did not take part in peacekeeping – a particularly puzzling absence given that this was a period of increased Brazilian activism at the UN, including in international security issues. This article suggests that one of the main reasons for Brazil’s withdrawal was concern regarding the excessive role of the great powers in controlling these operations. From 1967 to 1977, Brazil participated in the attempt to stop the Security Council from consolidating its control over these operations, seeking thereby to reduce their vulnerability to great power manipulation. In 1977, it desisted from this endeavor, and returned to peacekeeping only in 1989, by which time Brazil, the world, and peacekeeping had all changed significantly.

Original footage of the Chilean miners with manganism published in Neurology in 1967.

Science.gov (United States)

Miranda, Marcelo; Bustamante, M Leonor; Mena, Francisco; Lees, Andrew

2015-12-15

Manganism has captured the imagination of neurologists for more than a century because of its similarities to Parkinson disease and its indirect but seminal role in the "l-dopa miracle." We present unpublished footage of the original case series reported in Neurology® in 1967 by Mena and Cotzias depicting the typical neurologic signs of manganism in 4 Chilean miners and their response to high doses of l-dopa. © 2015 American Academy of Neurology.

Esclavos perfectos: historia breve de la ciberarquitectura en MIT (1959-1967

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Daniel Cardoso Llach

2012-07-01

Full Text Available This paper addresses unexplored aspects of the relationship between military research at MIT, and the constitution, during the cold war years, of a techno-scientific discourse of architecture. Exploring primary sources from the "Computer-Aided Design Project" (1959-1967, this paper explains the emergence of a cybernetic understanding of design, and its transit into architectural culture. The article presents Nicholas Negroponte's use of the CAD project's technical and theoretical idioms to re-imagine architectural practice through a technocratic (and populist lens, and discusses aspects of its influence in contemporary techno-scientific design discourse.

Perang Enam Hari Arab Israel 1967 Menerusi Perspektif Teori Realisme

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MOHD IRWAN SYAZLI SAIDIN

2016-06-01

Full Text Available Realism approach has dominated the studies of world politics and international relations since the last of the World War II and until the start of the Cold War era. The focus of this study is to look into the factors that ignited the war other than identifying the policies or actions taken by the countries involved in the war. The question that arises lies in the extent to which the approach is able to explain the factors and actions taken by the leaders, to the point that it led to the 1967 war, and how this war can serve as guidance for our understanding of the Realism Theory. The objective of this study is to unravel the chains of events that had become the background of the 1967 Arab-Israeli War by concentrating on the root causes of the war and the policies of the countries involved, other than offering justification for the Realism Theory by looking closely into the characteristics, assumptions, and concepts under this approach. The methodology of this work employs document analysis and historical studies to obtain complete data. The analysis was carried out by applying the Arab-Israeli war events to the Realism Theory to prove that there is an association between the causes of the war and the theory through the analysis unit, key assumptions and substantial concepts contained in the Realism approach. The unit of analysis, which places the countries as the main actor in the international system, can be seen through the main role of Egypt, Jordan, Syria and Israel throughout the period of war. Concepts such as power, power balance, national interests, national sovereignty and self-help are also associated with the causes behind this war through a series of facts that have manifested themselves in the event

Executive Succession and Institutional Change: A Case Study of the University of New Mexico, 1967-1972.

Science.gov (United States)

Bjork, Lars G.

The history of the University of New Mexico during 1967-1972, when a new president was appointed, is examined. Attention is focused primarily on the environmental milieu relating to federal support of university research and the president's leadership initiative in establishing the Office of the Vice President for Research. In reviewing…

Development of estimation method for crop yield using MODIS satellite imagery data and process-based model for corn and soybean in US Corn-Belt region

Science.gov (United States)

Lee, J.; Kang, S.; Jang, K.; Ko, J.; Hong, S.

2012-12-01

Crop productivity is associated with the food security and hence, several models have been developed to estimate crop yield by combining remote sensing data with carbon cycle processes. In present study, we attempted to estimate crop GPP and NPP using algorithm based on the LUE model and a simplified respiration model. The state of Iowa and Illinois was chosen as the study site for estimating the crop yield for a period covering the 5 years (2006-2010), as it is the main Corn-Belt area in US. Present study focuses on developing crop-specific parameters for corn and soybean to estimate crop productivity and yield mapping using satellite remote sensing data. We utilized a 10 km spatial resolution daily meteorological data from WRF to provide cloudy-day meteorological variables but in clear-say days, MODIS-based meteorological data were utilized to estimate daily GPP, NPP, and biomass. County-level statistics on yield, area harvested, and productions were used to test model predicted crop yield. The estimated input meteorological variables from MODIS and WRF showed with good agreements with the ground observations from 6 Ameriflux tower sites in 2006. For examples, correlation coefficients ranged from 0.93 to 0.98 for Tmin and Tavg ; from 0.68 to 0.85 for daytime mean VPD; from 0.85 to 0.96 for daily shortwave radiation, respectively. We developed county-specific crop conversion coefficient, i.e. ratio of yield to biomass on 260 DOY and then, validated the estimated county-level crop yield with the statistical yield data. The estimated corn and soybean yields at the county level ranged from 671 gm-2 y-1 to 1393 gm-2 y-1 and from 213 gm-2 y-1 to 421 gm-2 y-1, respectively. The county-specific yield estimation mostly showed errors less than 10%. Furthermore, we estimated crop yields at the state level which were validated against the statistics data and showed errors less than 1%. Further analysis for crop conversion coefficient was conducted for 200 DOY and 280 DOY

Industry will meet productivity goals, but can it hold the line on prices: electrical Canada, 1967

Energy Technology Data Exchange (ETDEWEB)

1967-01-01

The Canadian electrical industry can expect to grow more muscle in 1967. Demand for electricity increases across the country and the big power projects will be the Nelson Columbia, Peace, Manicouagan, Outardes and Churchill Falls. With more promotion by utilities scheduled better electrical living will get a record shot in the arm.

Effect of Strip Mining on Water Quality in Small Streams in Eastern Kentucky, 1967-1975

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Kenneth L. Dyer; Willie R. Curtis

1977-01-01

Eight years of streamflow data are analyzed to show the effects of strip mining on chemical quality of water in six first-order streams in Breathitt County, Kentucky. All these watersheds were unmined in August, 1967, but five have since been strip mined. The accumulated data from this case history study indicate that strip mining causes large increases in the...

Le développement de la graphique de 1967 à 1997

OpenAIRE

Bonin, Serge

2014-01-01

La Sémiologie graphique a été publiée en 1967. Il y a trente ans. Le Laboratoire de Cartographie de la 6ème section de l’École Pratique des Hautes Études existait depuis une douzaine d’années ; créé par Lucien Febvre et soutenu par Fernand Braudel, présidents de l’institution, Jacques Bertin en était le directeur. Depuis, la 6ème section de l’École Pratique des Hautes Études est devenue l’École des Hautes Études en Sciences Sociales, et le Laboratoire de Cartographie, laboratoire de service, ...

Music and 're-education' in Greek prison camps: from Makronisos (1947-1955) to Giaros (1967-1968).

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Papaeti, Anna

2013-01-01

This paper examines the policy of 're-education' for left-wing political prisoners in Greece during the military Junta (1967-1974) at the prison camp on the island of Giaros from 1967 to November 1968. Taking as its starting point the ways folk culture was used to substantiate the Colonels' ideological discourse and to give their rule aesthetic roots as a strategy of legitimization, the paper investigates how this kind of music was instrumentalized as a way of breaking political prisoners in exile. Music from loudspeakers was part of an attempt to make detainees sign Declarations of Loyalty, renouncing their values and their comrades. The 're-education' programme of Giaros is examined here as a remainder of the Greek Civil-War legacy (1946-1949), and particularly of the institutionalized 're-education' and 'rehabilitation' programme of the infamous prison camps on the island of Makronisos (1947-1955). Interviews with former detainees from both historical periods underline the damaging effects of the use of music, highlighting the need to understand music's capacity to degrade, but also torture, individuals instead of uplift and ennoble the soul.

Using MODIS Data to Predict Regional Corn Yields

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Ho-Young Ban

2016-12-01

Full Text Available A simple approach was developed to predict corn yields using the MoDerate Resolution Imaging Spectroradiometer (MODIS data product from two geographically separate major corn crop production regions: Illinois, USA and Heilongjiang, China. The MOD09A1 data, which are eight-day interval surface reflectance data, were obtained from day of the year (DOY 89 to 337 to calculate the leaf area index (LAI. The sum of the LAI from early in the season to a given date in the season (end of DOY (EOD was well fitted to a logistic function and represented seasonal changes in leaf area duration (LAD. A simple phenology model was derived to estimate the dates of emergence and maturity using the LAD-logistic function parameters b1 and b2, which represented the rate of increase in LAI and the date of maximum LAI, respectively. The phenology model predicted emergence and maturity dates fairly well, with root mean square error (RMSE values of 6.3 and 4.9 days for the validation dataset, respectively. Two simple linear regression models (YP and YF were established using LAD as the variable to predict corn yield. The yield model YP used LAD from predicted emergence to maturity, and the yield model YF used LAD for a predetermined period from DOY 89 to a particular EOD. When state/province corn yields for the validation dataset were predicted at DOY 321, near completion of the corn harvest, the YP model, including the predicted phenology, performed much better than the YF model, with RMSE values of 0.68 t/ha and 0.66 t/ha for Illinois and Heilongjiang, respectively. The YP model showed similar or better performance, even for the much earlier pre-harvest yield prediction at DOY 257. In addition, the model performance showed no difference between the two study regions with very different climates and cultivation methods, including cultivar and irrigation management. These results suggested that the approach described in this paper has potential for application to

The provision of modern medical services to a nomadic population: a review of medical services to the Bedouins of southern Sinai during Israeli rule 1967-1982.

Science.gov (United States)

Romem, Pnina; Reizer, Haya; Romem, Yitzhak; Shvarts, Shifra

2002-04-01

Southern Sinai, a mountainous desolated arid area, is inhabited by Bedouin nomad tribes composed of Arabic-speaking Moslems. Until the Six Day War between Egypt and Israel in 1967, healthcare services in the region were based on traditional medicine performed by the Darvish, a local healer. Over the course of Israeli rule (1967-1982) an elaborate healthcare service was established and maintained, providing modern, up to date, comprehensive medical services that were available to all free of charge.

Charles de Gaulle et le Moyen Orient après 1967: la lecture des événements politiques et leur influence sur la prise de position de De Gaulle en 1967

OpenAIRE

Crețanu, Andrada

2016-01-01

In 1958, during the Algerian crisis, the return of General de Gaulle to power had a significant impact on the conduct of Franco-Israeli relations. Thus, after the Algerian independence completed in 1962, Gaullist policy moved towards the restoration of the old relations of "friendship and cooperation" with the Arab world, in line with "his reason and his feelings". This change of direction is noticeable in 1967, when France is the only Western country to have taken a critical stance toward Is...

A shock surface geometry - The February 15-16, 1967, event. [solar flare associated interplanetary shock

Science.gov (United States)

Lepping, R. P.; Chao, J. K.

1976-01-01

An estimated shape is presented for the surface of the flare-associated interplanetary shock of February 15-16, 1967, as seen in the ecliptic-plane cross section. The estimate is based on observations by Explorer 33 and Pioneers 6 and 7. The estimated shock normal at the Explorer 33 position is obtained by a least-squares shock parameter-fitting procedure for that satellite's data; the shock normal at the Pioneer 7 position is found by using the magnetic coplanarity theorem and magnetic-field data. The average shock speed from the sun to each spacecraft is determined along with the local speed at Explorer 33 and the relations between these speeds and the position of the initiating solar flare. The Explorer 33 shock normal is found to be severely inclined and not typical of interplanetary shocks. It is shown that the curvature of the shock surface in the ecliptic plane near the earth-Pioneer 7 region is consistent with a radius of not more than 0.4 AU.

Outline of fiscal 1967 achievements in research on MHD power generation; 1967 nendo MHD hatsuden kenkyu seika gaiyo

Energy Technology Data Exchange (ETDEWEB)

NONE

1968-09-01

Compiled are the results of studies conducted in fiscal 1967 on MHD (magnetohydrodynamic) power generation. In the test operation and modification of a 1,000kW-class MHD power generator at the Electrical Research Laboratory, a test is conducted using Faraday-type electrodes. It is then found that this configuration results in a maximum output of approximately 700kW, which is less than expected. In the experimental construction at the Hitachi, Ltd., of a machine capable of a long-term operation, an MHD power generator is built for a continuous operation of 100 hours with an maximum output of 2kW, and a 110-hour power generation is successfully achieved with a maximum output of 1.9kW. In the research and development of heat exchangers, tests are conducted for a bulkhead type heat exchanger, heat accumulator type heat exchanger, molten slag type heat exchanger, and a gas/liquid 2-phase flow type heat exchanger. In the study of heat-resisting insulators, materials based on zirconate, magnesia, thoria, zirconia, etc., are tested. In addition, studies are conducted on electrode materials, superconductive electromagnets (small superconductive electromagnets for MHD power generators, turbine type helium liquefiers, superconductive wires for 70-kilogauss electromagnets, etc.), and thermal performance rating. (NEDO)

26 CFR 1.981-2 - Foreign law community income for taxable years beginning before January 1, 1967.

Science.gov (United States)

2010-04-01

... paragraph (c) of § 1.981-3. (c) Time and manner of making election—(1) In general. A citizen of the United... election applies, (iv) The office of the district director, or the service center, where the return or...-2 Foreign law community income for taxable years beginning before January 1, 1967. (a) Election for...

Fiscal policy and growth: new results for the Spanish regions, 1967-1995

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Óscar Bajo Rubio

2003-01-01

Full Text Available In this paper we present a new assessment of the effects of fiscal policy on economic growth, focusing on the role of public expenditure. Starting from a theoretical model where only those public expenditure items strictly presumed to influence the production process (i.e., public capital and transfers are incorporated into the production function, we provide an empirical application for the case of the Spanish regions during the period 1967-1995. The results confirm the positive effect on growth from both public capital and transfers, being relatively more intense that of public capital for the more productive regions, and that of transfers for the less productive ones.

The SETI episode in the 1967 discovery of pulsars

Science.gov (United States)

Penny, Alan John

2013-09-01

In the winter of 1967 Cambridge radio astronomers discovered a new type of radio source of such an artificial seeming nature that for a few weeks some members of the group had to seriously consider whether they had discovered an extraterrestrial intelligence. Although their investigations lead them to a natural explanation (they had discovered pulsars), they had discussed the implications if it was indeed an artificial source: how to verify such a conclusion and how to announce it, and whether such a discovery might be dangerous. In this they presaged many of the components of the SETI Detection Protocols and the proposed Reply Protocols which have been used to guide the responses of groups dealing with the detection of an extraterrestrial intelligence. These Protocols were only established some twenty five years later in the 1990s and 2000s. Using contemporary and near-contemporary documentation and later recollections, this paper discusses in detail what happened that winter.

Measurement of Galaxy Cluster Integrated Comptonization and Mass Scaling Relations with the South Pole Telescope

Energy Technology Data Exchange (ETDEWEB)

Saliwanchik, B. R.; et al.

2015-01-22

We describe a method for measuring the integrated Comptonization (Y (SZ)) of clusters of galaxies from measurements of the Sunyaev-Zel'dovich (SZ) effect in multiple frequency bands and use this method to characterize a sample of galaxy clusters detected in the South Pole Telescope (SPT) data. We use a Markov Chain Monte Carlo method to fit a β-model source profile and integrate Y (SZ) within an angular aperture on the sky. In simulated observations of an SPT-like survey that include cosmic microwave background anisotropy, point sources, and atmospheric and instrumental noise at typical SPT-SZ survey levels, we show that we can accurately recover β-model parameters for inputted clusters. We measure Y (SZ) for simulated semi-analytic clusters and find that Y (SZ) is most accurately determined in an angular aperture comparable to the SPT beam size. We demonstrate the utility of this method to measure Y (SZ) and to constrain mass scaling relations using X-ray mass estimates for a sample of 18 galaxy clusters from the SPT-SZ survey. Measuring Y (SZ) within a 0.'75 radius aperture, we find an intrinsic log-normal scatter of 21% ± 11% in Y (SZ) at a fixed mass. Measuring Y (SZ) within a 0.3 Mpc projected radius (equivalent to 0.'75 at the survey median redshift z = 0.6), we find a scatter of 26% ± 9%. Prior to this study, the SPT observable found to have the lowest scatter with mass was cluster detection significance. We demonstrate, from both simulations and SPT observed clusters that Y (SZ) measured within an aperture comparable to the SPT beam size is equivalent, in terms of scatter with cluster mass, to SPT cluster detection significance.

An Approach to Flooding Inundation Combining the Streamflow Prediction Tool (SPT) and Downscaled Soil Moisture

Science.gov (United States)

Cotterman, K. A.; Follum, M. L.; Pradhan, N. R.; Niemann, J. D.

2017-12-01

Flooding impacts numerous aspects of society, from localized flash floods to continental-scale flood events. Many numerical flood models focus solely on riverine flooding, with some capable of capturing both localized and continental-scale flood events. However, these models neglect flooding away from channels that are related to excessive ponding, typically found in areas with flat terrain and poorly draining soils. In order to obtain a holistic view of flooding, we combine flood results from the Streamflow Prediction Tool (SPT), a riverine flood model, with soil moisture downscaling techniques to determine if a better representation of flooding is obtained. This allows for a more holistic understanding of potential flood prone areas, increasing the opportunity for more accurate warnings and evacuations during flooding conditions. Thirty-five years of near-global historical streamflow is reconstructed with continental-scale flow routing of runoff from global land surface models. Elevation data was also obtained worldwide, to establish a relationship between topographic attributes and soil moisture patterns. Derived soil moisture data is validated against observed soil moisture, increasing confidence in the ability to accurately capture soil moisture patterns. Potential flooding situations can be examined worldwide, with this study focusing on the United States, Central America, and the Philippines.

The Center for Intercultural Formation, Cuernavaca, Mexico, its reports (1962-1967 and Illich’s critical understanding of mission in Latin America

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Bruno-Jofré, Rosa

2014-12-01

Full Text Available This paper examines the Reports of the Center for Intercultural Formation (CIF, which were produced in Cuernavaca, Mexico, between 1962-1967 by the Centro de Investigaciones Culturales (Center for Cultural Research (CIC, and supported since 1963 by the Centro Intercultural de Documentación (Center for Intercultural Documentation (CIDOC (an offshoot of CIC. The network is placed within the historical conjuncture of the early 1960s and the alignment of the Vatican with the Alliance for Progress and its anti-communist developmentalist community projects. The core of the paper centers in the ‘illocutionary force’ (Quentin Skinner behind Illich’s responses to John XXIII’s call to congregations and lay Catholics for a renewed mission in Latin America. It addresses Illich’s resignification of the understanding of mission and missioner rooted in the Gospel, the notion of incarnation in the culture rather than missioners being agents of their culture, and missionary “poverty” as a virtue of the community worker. Illich’s radicalization of his critical discourse led to a confrontation with the Vatican in 1967 and 1968 after he published “The Seamy Side of Charity” and “The Vanishing Clergyman” in the last year, 1967, of the CIF Report. The conflict with the Vatican signaled Illich’s turn to educational, health and other issues moving away from a critique of the institutionalized Catholic Church.Este artículo examina los Reports del Center of Intercultural Formation (CIF que fueron elaborados en Cuernavaca, México, entre 1962 y 1967 por el Centro de Investigaciones Culturales (CIC, y producidos desde 1963 por el Centro Intercultural de Documentación constituido dentro del CIC. Esta red de centros es situada dentro de la coyuntura histórica del principio de los años sesenta y de la convergencia entre el Vaticano y la Alianza para el Progreso y sus proyectos comunitarios desarrollistas. El artículo se centra en la �

Report on the Workshop on the Use of Radio and Television in Workers' Education (Geneva, 20-30 November 1967).

Science.gov (United States)

International Labour Office, Geneva (Switzerland). International Vocational Training Information and Research Centre.

The potential value of radio and television in labor education, technical aspects, information dissemination, practical measures for promoting labor education broadcasting, and additional means of promoting the production of suitable program materials were discussed at this 1967 International Labour Office (ILO) workshop of labor educators and…

An Extended Fourier Approach to Improve the Retrieved Leaf Area Index (LAI in a Time Series from an Alpine Wetland

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Xingwen Quan

2014-01-01

Full Text Available An extended Fourier approach was presented to improve the retrieved leaf area index (LAIr of herbaceous vegetation in a time series from an alpine wetland. The retrieval was performed from the Aqua MODIS 8-day composite surface reflectance product (MYD09Q1 from day of year (DOY 97 to 297 using a look-up table (LUT based inversion of a two-layer canopy reflectance model (ACRM. To reduce the uncertainty (the ACRM inversion is ill-posed, we used NDVI and NIR images to reduce the influence of the soil background and the priori information to constrain the range of sensitive ACRM parameters determined using the Sobol’s method. Even so the uncertainty caused the LAIr versus time curve to oscillate. To further reduce the uncertainty, a Fourier model was fitted using the periodically LAIr results, obtaining LAIF. We note that the level of precision of the LAIF potentially may increase through removing singular points or decrease if the LAIr data were too noisy. To further improve the precision level of the LAIr, the Fourier model was extended by considering the LAIr uncertainty. The LAIr, the LAI simulated using the Fourier model, and the LAI simulated using the extended Fourier approach (LAIeF were validated through comparisons with the field measured LAI. The R2 values were 0.68, 0.67 and 0.72, the residual sums of squares (RSS were 3.47, 3.42 and 3.15, and the root-mean-square errors (RMSE were 0.31, 0.30 and 0.29, respectively, on DOY 177 (early July 2011. In late August (DOY 233, the R2 values were 0.73, 0.77 and 0.79, the RSS values were 38.96, 29.25 and 27.48, and the RMSE values were 0.94, 0.81 and 0.78, respectively. The results demonstrate that the extended Fourier approach has the potential to increase the level of precision of estimates of the time varying LAI.

PROCEEDINGS OF INTERNATIONAL CONFERENCE ON ORAL EDUCATION OF THE DEAF. VOLUME I. (WASHINGTON, D.C., NOVEMBER 1, 1967).

Science.gov (United States)

Alexander Graham Bell Association for the Deaf, Inc., Washington, DC.

THE PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON ORAL EDUCATION OF THE DEAF ARE THE WRITTEN RECORD OF A CONFERENCE HELD AT CLARKE SCHOOL FOR THE DEAF AND LEXINGTON SCHOOL FOR THE DEAF IN JUNE 1967. VOLUME I CONTAINS THE PAPERS FROM FIVE PLENARY SESSIONS AND SEVERAL SECTIONAL MEETINGS PRESENTED BY REPRESENTATIVES FROM 16 COUNTRIES. SUBJECTS…

WATER TEMPERATURE and Other Data from ALMIRANTE SALDANHA From SW Atlantic (limit-20 W) for 1967-01-01 (NODC Accession 9700076)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Phytoplankton, chlorophyll, and other data were collected from bottle casts in the SW Atlantic Ocean (lim-20 W) from the Almirante Saldanha from 16 March 1967 to 30...

La ciudad socialista: Visión y práctica urbana del Partido Comunista de Chile, 1967-1973 The socialist city: vision and urban practice of the Communist Party of Chile, 1967-1973

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Boris Cofré

2012-08-01

Full Text Available ¿Tuvieron los comunistas chilenos, entre 1967 y 1973, una visión propia sobre el problema urbano en Santiago? de ser así ¿cómo era la ciudad que los comunistas buscaban construir en la capital? Inspirados tanto en el marxismo y el modelo Soviético de desarrollo urbano, como en sus prácticas políticas concretas a nivel nacional, comunal y barrial, los comunistas no sólo imaginaron una urbe distinta sino que avanzaron en su construcción.

Electrochemistry of chromium(0)-aminocarbene complexes

International Nuclear Information System (INIS)

Hoskovcova, Irena; Rohacova, Jana; Meca, Ludek; Tobrman, Tomas; Dvorak, Dalimil; Ludvik, Jiri

2005-01-01

Two series of chromium(0)-(aryl)aminocarbene complexes substituted on the ligand phenyl ring were prepared and electrochemically investigated: pentacarbonyl((N,N-dimethylamino)(phenyl)carbene(chromium(0) (Ia-e) and chelated tetracarbonyl((η 2 -N-allyl-N-allylamino)(phenyl)carbene(chromium(0) (IIa, c-e). For comparison, a tungsten analogue of IIc (III) and a chromium chelate bearing a methyl substituent instead of the phenyl group IV were taken into the study. The intramolecular interactions of p-substituents on the ligand phenyl ring with the reduction and oxidation centres of the molecule of complex (followed electrochemically using LFER [P. Zuman, Substituent Effects in Organic Polarography, Plenum Press, New York, 1967]) enabled to localize the corresponding electron transfer. The influence of the type of coordination, the substituent on the ligand phenyl ring and the central metal atom on oxidation and reduction potentials is discussed

GSTM1 copy number and promoter haplotype as predictors for risk of recurrence and/or second primary tumor in patients with head and neck cancer

Directory of Open Access Journals (Sweden)

Zhang X

2013-03-01

Full Text Available Xuemei Zhang,1 Maosheng Huang,2 Xifeng Wu,2 Susan Kadlubar,1 Jie Lin,2 Xinfeng Yu,1 Chunyang Fan,3 Baitang Ning,4 Fred F Kadlubar1†1University of Arkansas for Medical Sciences, Little Rock, Arkansas, 2The University of Texas MD Anderson Cancer Center, Houston, Texas, 3VA hospital, Little Rock, Arkansas, 4National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas, USA†Fred F Kadlubar passed away on December 4, 2010.Abstract: The objective of this study was to determine copy number variant (CNV and promoter genetic variants in glutathione S-transferase Mu class 1 (GSTM1 and the risk of recurrence (REC/second primary tumor (SPT in patients with previously diagnosed early stage head and neck cancer. Among 441 subjects, 133 experienced REC and/or an SPT, while 308 had single primary disease. TaqMan real-time polymerase chain reaction was used to measure the exact copy number of GSTM1 and direct sequencing was used to determine genetic variants in the GSTM1 promoter region. Multivariate Cox regression analysis was performed to estimate hazard ratios (HRs and 95% confidence intervals (95% CIs associated with copy number and genetic variants. REC/SPT-free survival times were compared by constructing Kaplan–Meier curves and differences between curves were tested by logrank test. Results showed a significantly decreased REC/SPT (HR = 0.57; 95% CI = 0.35–0.95 and longer REC/SPT-free survival in subjects with at least two copies of GSTM1 compared with the GSTM1 homozygous deletion, but not in those with one copy of GSTM1. The −498G, −426G, and −339T alleles were significantly associated with REC/SPT, with HRs of 0.11 (0.02–0.85, 0.28 (0.11–0.74 and 2.02 (1.07–3.82, respectively. Kaplan–Meier survival analysis showed that the −498G, −426G, and −339C alleles were also significantly associated with increased REC/SPT-free survival. Further haplotype analysis showed the haplotype P-498G--426G--339

Functional insight into the C-terminal extension of halolysin SptA from haloarchaeon Natrinema sp. J7.

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Zhisheng Xu

Full Text Available Halolysin SptA from haloarchaeon Natrinema sp. J7 consists of a subtilisin-like catalytic domain and a C-terminal extension (CTE containing two cysteine residues. In this report, we have investigated the function of the CTE using recombinant enzymes expressed in Haloferax volcanii WFD11. Deletion of the CTE greatly reduced but did not abolish protease activity, which suggests that the CTE is not essential for enzyme folding. Mutational analysis suggests that residues Cys303 and Cys338 within the CTE form a disulfide bond that make this domain resistant to autocleavage and proteolysis under hypotonic conditions. Characterization of full-length and CTE-truncation enzymes indicates the CTE not only confers extra stability to the enzyme but also assists enzyme activity on protein substrates by facilitating binding at high salinities. Interestingly, homology modeling of the CTE yields a β-jelly roll-like structure similar to those seen in Claudin-binding domain of Clostridium perfringens enterotoxin (clostridial C-CPE and collagen binding domain (CBD, and the CTE also possesses collagen-binding activity, making it a potential candidate as an anchoring unit in drug delivery systems.

Review of the genus Merulempista Roesler, 1967 (Lepidoptera, Pyralidae from China, with description of two new species

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Yingdang Ren

2011-01-01

Full Text Available The genus Merulempista Roesler, 1967 is reviewed for China. Of the four species treated in this paper, Merulempista rubriptera Li & Ren, sp. n. and M. digitata Li & Ren, sp. n. are described as new; M. cyclogramma (Hampson, 1896 is newly recorded for China, and its taxonomic position is briefly discussed. Photographs of the adults and genitalia are provided, along with a key to the known Chinese species.

The mediating effects of childhood neglect on the association between schizotypal and autistic personality traits and depression in a non-clinical sample.

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Liu, Jianbo; Gong, Jingbo; Nie, Guanghui; He, Yuqiong; Xiao, Bo; Shen, Yanmei; Luo, Xuerong

2017-10-25

Autistic personality traits (APT) and schizotypal personality traits (SPT) are associated with depression. However, mediating factors within these relationships have not yet been explored. Thus, the focus of the current study was to examine the effects of childhood neglect on the relationship between APT/SPT and depression. This cross-sectional study was conducted on first-year students (N = 2469) at Hunan University of Chinese Medicine and Hengyang Normal College (Changsha, China). Participants completed surveys on APT, SPT, childhood neglect, abuse and depression. Through correlational analyses, APT and SPT traits were positively correlated with childhood neglect and depression (p childhood maltreatment, emotional neglect (β = 0.112, p Childhood neglect did not account for the relationships between APT/SPT and depression. Further analysis found that childhood neglect mediated the relationship between SPT and depression but not APT and depression. Among types of childhood maltreatment, neglect was the strongest predicting factor for depression. Neglect did not account for the relationship between APT/SPT and depression but was a strong mediating factor between SPT and depression.

[The role of the basophil activation test (BAT) in qualification for specific immunotherapy with inhalant allergens].

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Bulanda, Małgorzata; Dyga, Wojciech; Rusinek, Barbara; Czarnobilska, Ewa

Qualification for specific immunotherapy (SIT) according to the guidelines of the European Academy of Allergy and Clinical Immunology (EAACI) includes medical history, skin prik tests (SPT) and/or measuring the concentration of sIgE. It is necessary to perform additional diagnostic tests in case of discrepancies between the history and the results of SPT/sIgE or differences between SPT and sIgE. Basophil activation test (BAT) assesses the expression of activation markers of these cells, eg. CD63 and CD203c after stimulation. The aim of our study was to evaluate the usefulness of BAT in the qualification for the SIT in comparison to the SPT and sIgE and in case of discrepancies between the results of SPT and sIgE. The study included 30 patients with allergic rhinitis (AR) caused by allergy to house dust mite (Dermatophagoides pteronyssinus, Dp) or birch pollen qualified for SIT. All patients had SPT, sIgE and BAT determination. The group of patients with allergy to birch was a control group for Dp allergic and vice versa. BAT with CD63 antigen expression was performed using a Flow2CAST test. Basophils were stimulated with allergen preparation (50, 500, and 5000 SBU/ml concentrations). BAT results were expressed as a stimulation index (SI). For optimal concentrations of 50 and 500 SBU/ml parameters comparing BAT to SPT and sIgE as the gold standards were consecutively: sensitivity 82-100% and 93-100%, specificity 50-94% and 47-89%, positive predictive value 65- 94% and 61-87%, negative predictive value 86-100% and 93-100%. Correlation BAT - SPT and BAT - sIgE ranged within 0.59 to 0.84 and 0.51 to 0.72. BAT was helpful in 2 of 30 patients with incompatible results of SPT and sIgE. Optimal concentrations for basophil stimulation are 50 and 500 SBU/ ml. BAT may be useful diagnostic tool in the qualification for the SIT in case of discrepancies between the results of SPT and sIgE.

SOUTH POLE TELESCOPE DETECTIONS OF THE PREVIOUSLY UNCONFIRMED PLANCK EARLY SUNYAEV-ZEL'DOVICH CLUSTERS IN THE SOUTHERN HEMISPHERE

International Nuclear Information System (INIS)

Story, K.; Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Crawford, T. M.; Crites, A. T.; Aird, K. A.; Andersson, K.; Bazin, G.; Armstrong, R.; Desai, S.; Bonamente, M.; Brodwin, M.; Foley, R. J.; Clocchiatti, A.; De Haan, T.; Dobbs, M. A.; Dudley, J. P.; George, E. M.

2011-01-01

We present South Pole Telescope (SPT) observations of the five galaxy cluster candidates in the southern hemisphere which were reported as unconfirmed in the Planck Early Sunyaev-Zel'dovich (ESZ) sample. One cluster candidate, PLCKESZ G255.62-46.16, is located in the 2500 deg 2 SPT SZ survey region and was reported previously as SPT-CL J0411-4819. For the remaining four candidates, which are located outside of the SPT SZ survey region, we performed short, dedicated SPT observations. Each of these four candidates was strongly detected in maps made from these observations, with signal-to-noise ratios ranging from 6.3 to 13.8. We have observed these four candidates on the Magellan-Baade telescope and used these data to estimate cluster redshifts from the red sequence. Resulting redshifts range from 0.24 to 0.46. We report measurements of Y 0.'75 , the integrated Comptonization within a 0.'75 radius, for all five candidates. We also report X-ray luminosities calculated from ROSAT All-Sky Survey catalog counts, as well as optical and improved SZ coordinates for each candidate. The combination of SPT SZ measurements, optical red-sequence measurements, and X-ray luminosity estimates demonstrates that these five Planck ESZ cluster candidates do indeed correspond to real galaxy clusters with redshifts and observable properties consistent with the rest of the ESZ sample.

Revision of Brada Stimpson, 1853, and Bradabyssa Hartman, 1967 (Annelida, Flabelligeridae).

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Salazar-Vallejo, Sergio I

2017-11-03

Among flabelligerid genera Brada Stimpson, 1853 includes several species whose bodies are fusiform or club-shaped, often with a reduced number of chaetigers, and their members are found in temperate and polar waters. In contrast, Bradabyssa Hartman, 1967 is regarded as a monotypic genus with a single Antarctic species with a cylindrical body and a variable number of chaetigers. After examination of all type and non-type material available of both genera, two distinct body patterns were distinguished: one includes the type species for Brada, B. granosa Stimpson, 1853, has only 8 branchial filaments and the neurochaetae are thick, blunt, often falcate, whereas the other includes the type species of Bradabyssa, B. papillata Hartman, 1967, usually has many branchial filaments and neurochaetae are straighter and mucronate. Consequently, Brada is herein restricted to include only 5 species, one of which is new, Brada kudenovi n. sp. Bradabyssa is herein emended to include many species formerly regarded as belonging in Brada, as new combinations, and species can be separated into four groups according to the development of the tunic and its sediment load. Thirteen new species of Bradabyssa are also described: B. indica n. sp., B. mexicana n. sp., B. alaskensis n. sp., B. elinae n. sp., B. grangieri n. sp., B. levensteinae n. sp., B. harrisae n. sp., B. hartmanae n. sp., B. jirkovi n. sp., B. kirkegaardi n. sp., B. monnioti n. sp., B. mezianei n. sp. and B. willeyi n. sp. The species belonging to Brada are B. granosa, B. granulosa Hansen, 1880, B. incrustata Støp-Bowitz, 1948, B. inhabilis (Rathke, 1843), and B. kudenovi n. sp. The species belonging to Bradabyssa are separated into four groups according to the development of their tunic and its sediment load. Group crustosa includes B. indica n. sp., B. mexicana n. sp., B. minuta (Amoureux, 1986) n. comb., and B. sachalina (Annenkova-Chlopina, 1922) n. comb. Group nuda includes B. alaskensis n. sp., B. antarctica (Hartman

Fertility in Islamic Republic of Iran: Levels, Trends and Differentials during Three Decades (1967-1996

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Farahani, Farideh Khalaj Abadi

2002-01-01

Full Text Available EnglishThis study focuses on the fertility levels and trends of Iranian women aged10-49 years during three decades, 1967-1996. Information was collected by interviewing a systematiccluster sample of 13,253 households. The basic date of concern was the date of each live born childfor a sample of women in reproductive age and whether the live born was alive at the time of thestudy. The detailed nature of these data collected for each birth enabled fertility rates to becalculated for exact periods before the survey, for exact calendar years. Higher fertility rates werefound for the period 10-15 and 15-20 years preceding the survey. These high fertility levels areprobably due to some socio-economic changes in favor of higher level of fertility immediately afterthe 1979 revolution. However the results of the present survey show during 1967-1996, the TFR1 haddropped from 6.38 to 2.88 (an expected TFR based on fertility behavior during 1992-96. This declinewas probably due to delay in marriage and policy changes in favor of population control particularlysince 1987. Despite this potential fertility decline in recent years, Iran is expected to face a babyboom as the offspring who were born during the 1976-86 reach to the reproductive age in the comingdecades.FrenchCette étude porte sur les niveaux et les tendances de fertilité chez les Iraniennes âgées de 10 à 49 ans sur une période de trente ans, soit de 1967-1996. L'information a été recueillie en interviewant un échantillon en grappes systématique de 13 253 ménages. La principale date qui nous intéresse est la date de naissance de chaque enfant vivant pour un échantillon de femmes en âge de procréer et le fait que l'enfant soit toujours en vie au moment de l'étude. La nature détaillée des données recueillies pour chaque naissance a permis d'établir les taux de fertilité pour les périodes précises avant le sondage pour les années civiles précises. Les taux de fertilité �

A shock surface geometry: The February 15--16, 1967, event

International Nuclear Information System (INIS)

Lepping, R.P.; Chao, J.K.

1976-01-01

The flare-associated interplanetary (IP) shock of February 15--16, 1967, observed by Explorer 33 and Pioneer 7 is analyzed to yield an estimation of the ecliptic plane geometry of the shock surface near 1 AU. These spacecraft were separated by 23degree in heliocentric longitude, and Pioneer 7 was at a distance of 1.12 AU from the sun. There was an 18.9-hour delay between the two observations. The estimated shock normal, obtained by using a least squares shock parameter fitting procedure for the Explorer 33 data, is found to be theta/subS//subE/=-53degree and phi/subS//subE/=198degree. The error cone angle for the shock normal of the Explorer 33 observation was approximately 7degree. This severely inclined shock normal is not typical of IP shocks. The shock normal at the Pioneer 7 position is found to be theta/subn/=-14degree and phi/subn/=161degree. However, the uncertainty is large (approx. =25degree for a 1sigma cone angle). Although a data gap occurred at the apparent time of passage of the disturbance at Pioneer 6,the recovered data did not suggest such a passage. A consistent picture of the shock propagation is given. The average shock speed from the sun to each spacecraft and the local speed at Explorer 33 and their relations to the position of the initiating solar flare are obtained and discussed. In the region of space between the earth and Pioneer 7 the shock surface radius of curvature in the ecliptic plane appears to have been 0.4 AU or less

Numerical Modeling of Water Fluxes in the Root Zone of Irrigated Pecan

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Shukla, M. K.; Deb, S.

2010-12-01

Information is still limited on the coupled liquid water, water vapor, heat transport and root water uptake for irrigated pecan. Field experiments were conducted in a sandy loam mature pecan field in Las Cruces, New Mexico. Three pecan trees were chosen to monitor diurnal soil water content under the canopy (approximately half way between trunk and the drip line) and outside the drip line (bare spot) along a transect at the depths of 5, 10, 20, 40, and 60 cm using TDR sensors. Soil temperature sensors were installed at an under-canopy locations and bare spot to monitor soil temperature data at depths of 5, 10, 20, and 40 cm. Simulations of the coupled transport of liquid water, water vapor, and heat with and without root water uptake were carried out using the HYDRUS-1D code. Measured soil hydraulic and thermal properties, continuous meteorological data, and pecan characteristics, e.g. rooting depth, leaf area index, were used in the model simulations. Model calibration was performed for a 26-day period from DOY 204 through DOY 230, 2009 based on measured soil water content and soil temperature data at different soil depths, while the model was validated for a 90-day period from DOY 231 through DOY 320, 2009 at bare spot. Calibrated parameters were also used to apply the model at under-canopy locations for a 116-day period from DOY 204 to 320. HYDRUS-1D simulated water contents and soil temperatures correlated well with the measured data at each depth. Numerical assessment of various transport mechanisms and quantitative estimates of isothermal and thermal water fluxes with and without root water uptake in the unsaturated zone within canopy and bare spot is in progress and will be presented in the conference.

Lax-Phillips scattering theory with two Hilbert spaces V(x)=0((1)/|x|β), β>1

International Nuclear Information System (INIS)

Brambila Paz, F.

1988-10-01

A scattering theory for the wave equation with a perturbation with compact support was developed by Lax and Phillips in 1967. Using Enss approach Phillips developed a Lax-Phillips scattering theory for perturbations V such that V(x)=0((1)/|x| β ), β>2. In this paper we develop a scattering theory for more general perturbations V, i.e. for V(x)=0((1)/|x| β ), β>1. (author). 8 refs

International Migration with Heterogeneous Agents: Theory and Evidence for Germany, 1967-2009

DEFF Research Database (Denmark)

Brücker, Herbert; Schröder, Philipp

2012-01-01

Temporary migration, though empirically relevant, is often ignored in formal models. This paper proposes a migration model with heterogeneous agents and persistent cross country income differentials that features temporary migration. In equilibrium there exists a positive relation between the stock...... of migrants and the income differential, while the net migration flow becomes zero. Consequently, existing empirical migration models, estimating net migration flows, instead of stocks, may be misspecified. This suspicion appears to be confirmed by our investigation of the cointegration relationships...... of German migration stocks and flows since 1967. We find that (i) panel-unit root tests reject the hypothesis that migration flows and the explanatory variables are integrated of the same order, while migration stocks and the explanatory variables are all I(1) variables, and (ii) the hypothesis...

Auditory-motor interaction revealed by fMRI: speech, music, and working memory in area Spt.

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Hickok, Gregory; Buchsbaum, Bradley; Humphries, Colin; Muftuler, Tugan

2003-07-01

The concept of auditory-motor interaction pervades speech science research, yet the cortical systems supporting this interface have not been elucidated. Drawing on experimental designs used in recent work in sensory-motor integration in the cortical visual system, we used fMRI in an effort to identify human auditory regions with both sensory and motor response properties, analogous to single-unit responses in known visuomotor integration areas. The sensory phase of the task involved listening to speech (nonsense sentences) or music (novel piano melodies); the "motor" phase of the task involved covert rehearsal/humming of the auditory stimuli. A small set of areas in the superior temporal and temporal-parietal cortex responded both during the listening phase and the rehearsal/humming phase. A left lateralized region in the posterior Sylvian fissure at the parietal-temporal boundary, area Spt, showed particularly robust responses to both phases of the task. Frontal areas also showed combined auditory + rehearsal responsivity consistent with the claim that the posterior activations are part of a larger auditory-motor integration circuit. We hypothesize that this circuit plays an important role in speech development as part of the network that enables acoustic-phonetic input to guide the acquisition of language-specific articulatory-phonetic gestures; this circuit may play a role in analogous musical abilities. In the adult, this system continues to support aspects of speech production, and, we suggest, supports verbal working memory.

Evaluation of autologous serum skin test and skin prick test reactivity to house dust mite in patients with chronic spontaneous urticaria.

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Zhiqiang Song

Full Text Available BACKGROUND: Chronic spontaneous urticaria (CSU is a common skin disorder with etiology that is not well understood. METHODS: In this study, we evaluated the prevalence of autologous serum skin test (ASST and skin prick testing (SPT to house dust mite (HDM in 862 CSU cases in China. Clinical features, courses and treatment responses were also recorded. RESULTS: The prevalence of positive ASST was 46.3%, and patients aged 30-39 years had the highest positive rate (52.1%. Positive SPT to HDM was seen in 153 patients (17.7% with the highest positive rate (34.2% in patients aged 20 or less. Patients with positive ASST had higher urticaria activity scores (UAS (4.18±0.65 vs. 3.67±0.53 but lower positive rates of HDM (24.6% vs. 37.6%, as compared with those with negative ASST (odds ratio (OR 1.84, 95% CI 1.38-2.47. Patients could be categorized into four groups based on the results of ASST and SPT to HDM and patients with positive ASST and positive SPT to HDM had the highest disease activity scores, experienced higher frequencies of angioedema, diseases duration, and required higher dosage of loratadine every month, compared with other subgroups (P<0.0001. CONCLUSIONS: Patients with CSU showed varied responses of positive ASST and varied sensitivity to HDM, Patients with positive ASST and/or positive SPT had more disease activity compared with patients with negative ASST and/or negative SPT. Further classification can be made based on the result of SPT and ASST.

A Comparison of Maps and Power Spectra Determined from South Pole Telescope and Planck Data

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Hou, Z.; Aylor, K.; Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Cho, H-M.; Chown, R.; Crawford, T. M.; Crites, A. T.; de Haan, T.; Dobbs, M. A.; Everett, W. B.; Follin, B.; George, E. M.; Halverson, N. W.; Harrington, N. L.; Holder, G. P.; Holzapfel, W. L.; Hrubes, J. D.; Keisler, R.; Knox, L.; Lee, A. T.; Leitch, E. M.; Luong-Van, D.; Marrone, D. P.; McMahon, J. J.; Meyer, S. S.; Millea, M.; Mocanu, L. M.; Mohr, J. J.; Natoli, T.; Omori, Y.; Padin, S.; Pryke, C.; Reichardt, C. L.; Ruhl, J. E.; Sayre, J. T.; Schaffer, K. K.; Shirokoff, E.; Staniszewski, Z.; Stark, A. A.; Story, K. T.; Vanderlinde, K.; Vieira, J. D.; Williamson, R.

2018-01-17

We study the consistency of 150 GHz data from the South Pole Telescope (SPT) and 143 GHz data from the \\textit{Planck} satellite over the 2540 $\\text{deg}^2$ patch of sky covered by the SPT-SZ survey. We first visually compare the maps and find that the map residuals appear consistent with noise after we account for differences in angular resolution and filtering. To make a more quantitative comparison, we calculate (1) the cross-spectrum between two independent halves of SPT 150 GHz data, (2) the cross-spectrum between two independent halves of \\textit{Planck} 143 GHz data, and (3) the cross-spectrum between SPT 150 GHz and \\textit{Planck} 143 GHz data. We find the three cross-spectra are well-fit (PTE = 0.30) by the null hypothesis in which both experiments have measured the same sky map up to a single free parameter characterizing the relative calibration between the two. As a by-product of this analysis, we improve the calibration of SPT data by nearly an order of magnitude, from 2.6\\% to 0.3\\% in power; the best-fit power calibration factor relative to the most recent published SPT calibration is $1.0174 \\pm 0.0033$. Finally, we compare all three cross-spectra to the full-sky \\textit{Planck} $143 \\times 143$ power spectrum and find a hint ($\\sim$1.5$\\sigma$) for differences in the power spectrum of the SPT-SZ footprint and the full-sky power spectrum, which we model and fit as a power law in the spectrum. The best-fit value of this tilt is consistent between the three cross-spectra in the SPT-SZ footprint, implying that the source of this tilt---assuming it is real---is a sample variance fluctuation in the SPT-SZ region relative to the full sky. Despite the precision of our tests, we find no evidence for systematic errors in either data set. The consistency of cosmological parameters derived from these datasets is discussed in a companion paper.

Development of a novel iPad-based laparoscopic trainer and comparison with a standard laparoscopic trainer for basic laparoscopic skills testing.

Science.gov (United States)

Yoon, Renai; Del Junco, Michael; Kaplan, Adam; Okhunov, Zhamshid; Bucur, Philip; Hofmann, Martin; Alipanah, Reza; McDougall, Elspeth M; Landman, Jaime

2015-01-01

We developed the iTrainer (iT) as a portable laparoscopic trainer, which incorporates the iPad tablet. We then compared the iT with a standard pelvic trainer (SPT) to assess surgical skills as well as its image quality, resolution, brightness, comfort, and overall performance. We designed and constructed the iT to be compatible with the Apple iPad 3 and standard laparoscopic instruments. Participants were assigned to perform the thread-the-loops task on both trainers and were prospectively randomized to start on either the iT or the SPT. Each participant was allowed a 2-minute warm-up before the 2-minute testing period. We scored participants using the product of skill quality (0-4 scale) and quantity of loops threaded (0-10 scale). Participants then rated each trainer on image quality, resolution, brightness, comfort, and overall performance on a 5-point Likert scale. A total of 45 subjects including 10 undergraduates, 10 medical students, 10 general surgery and urology residents, and 15 experts (fellows and attending surgeons) participated in this study. There was no significant difference between thread-the-loops task scores completed on the iT when compared with the SPT for all groups tested (p > 0.05) with the exception of the medical student group, who performed better on the SPT (p < 0.05). On evaluation of each trainer, participants rated the iT as having superior image quality and resolution when compared with the SPT (p < 0.05) but rated the SPT higher in overall performance (p < 0.05). Brightness and comfort were rated similarly for both trainers. We have demonstrated face validity and criterion validity for the thread-the-loops task on the iT. The iT rated superior in image quality and resolution but inferior in overall performance compared with the SPT. The iT provides trainees a unique advantage over SPT as an additional resource to laparoscopic training as it is inexpensive, portable, and can be readily available for training. Copyright © 2014

Le développement de la graphique de 1967 à 1997

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Serge Bonin

2000-11-01

Full Text Available La Sémiologie graphique a été publiée en 1967. Il y a trente ans. Le Laboratoire de Cartographie de la 6ème section de l’École Pratique des Hautes Études existait depuis une douzaine d’années ; créé par Lucien Febvre et soutenu par Fernand Braudel, présidents de l’institution, Jacques Bertin en était le directeur. Depuis, la 6ème section de l’École Pratique des Hautes Études est devenue l’École des Hautes Études en Sciences Sociales, et le Laboratoire de Cartographie, laboratoire de service, est devenu le Laboratoire de Graphique, laboratoire de recherche. Trente sept ans d’activité au laboratoire, dont près de trente passés auprès de Jacques Bertin, m’autorisent à livrer une réflexion sur le développement de la Graphique, à faire un bilan vu de l’intérieur.

The therapeutic effects of radiotherapy of carcinoma of corpus uteri and cervix in the years 1967-1972

International Nuclear Information System (INIS)

Lembong, J.T.

1980-01-01

The results of radiotherapy of 374 cases of cancer of the cervix uteri, 163 cases of carcinoma of the endometrium, 24 cases of cancer of the cervival stump and 16 cases of sarkoma of the uterus carried out during the years 1967 to 1972 are shown. The absolute 5-year cure rates in our case material were 60,4 % for cancer of the cervix uteri and 73,0 % for carcinoma of the endometrium. In comparison with the treatment results reported in the years 1962 to 1966 an increase in radiotherapeutical efficiency was found, amounting to 8,8 % in case of cancer of the cervix uteri and 13,2 % in case of carcinoma of the endometrium. We also compared and analysed the different cure rates in case of primary irradiation (52,6 % resp. 55,8 %) as opposed to postoperative radiotherapy '76,9 % resp. 81,1 % cure rates). The frequency of radiation injuries and the rate of recurrence or metastases, as well as the incidence of concomitant diseases and complications have been reported and compared with those of other clinics. (orig./APR)

CARMELITA PINTO FONTES E O GINÁSIO DE APLICAÇÃO DA FACULDADE CATÓLICA DE FILOSOFIA DE SERGIPE (1961-1967

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Ane Rose de Jesus Santos Maciel

2016-03-01

Full Text Available Este artigo evidencia as ações pedagógicas da professora Carmelita Pinto Fontes no Ginásio de Aplicação da Faculdade Católica de Filosofia de Sergipe, entre os anos de 1961 a 1967. Esses estabelecimentos foram construídos como espaço de estágio para alunos concludentes dos cursos de Didática das Faculdades de Filosofia no Brasil, no entanto, tornaram-se um dos principais meios de divulgação de novas metodologias educacionais. Metodologicamente ancorado na pesquisa qualitativa, com apoio da História Cultural, da Educação e de Sergipe, além da História Oral, buscamos preencher lacunas deixadas pela historiografia da educação acerca de uma personagem importante para a configuração educacional que, através da educação, construiu sua trajetória intelectual em uma sociedade marcadamente masculina. Palavras-chave: Didática; Educação; Ginásio de Aplicação.   CARMELITA PINTO FONTES AND THE GYMNASIUM OF APPLICATION FROM THE CATHOLIC COLLEGE OF PHILOSOPHY OF SERGIPE (1961-1967 ABSTRACT This paper evidences the pedagogical actions from the professor Carmelita Pinto Fontes in the Gymnasium of Application from the Catholic College of Philosophy of Sergipe, through 1961 to 1967. These stablishment were built as a space of internship to senior students of the Didatic major from the Catholic College of Philosophy of Sergipe in Brazil; however, they became one of the main means for disseminating new educational technology. Methodologically anchored in qualitative research, with support of the Cultural History, Education and Sergipe, beyond of the Oral History, we seek to fill left gaps for the historiography of education about an important caracther to the educational configuration that built through education, her intellectual trajectory in a markedly male society. Keywords: Didatic; Education; Gymnasium of Application.   CARMELITA PINTO FONTES E O GIMNASIO DE APLICACIÓN DE LA FACULTAD CATÓLICA DE FILOSOFIA DE SERGIPE

Long-term outcome of radical radiation therapy for prostatic carcinoma: 1967-1987

International Nuclear Information System (INIS)

Hahn, Per; Baral, Edward; Cheang, Mary; Math, M.; Kostyra, Jeri; Roelss, Randall

1996-01-01

Purpose: This study was done to review long-term results of radical radiotherapy for prostate cancer. Methods and Materials: The records of 674 patients with Stage T1a, T1b, T2a, T2b, T3, and any T,N1,M0 disease, treated with external beam radiotherapy between January 1, 1967 and December 1987, were reviewed. These patients were treated to an average total dose of 66 Gy, with an average fractional dose of 2.05 Gy, using megavoltage. The duration of follow-up for surviving patients ranged from a minimum of 7 years to more than 20 years. Results: The survival for 151 Stage T1a,T1b patients was 98.5% at 5 years, 93.6% at 10 years, and 75.2% at 15 years. Survival for 346 Stage T2a,b patients was 94.4% at 5 years, 67.9% at 10 years, and 41.5% at 15 years. Survival for 92 Stage T3 patients was 87.3% at 5 years, 54% at 10 years, and 26.6% at 15 years. The survival for 85 any T,N1,M0 patients was 73.9% at 5 years, 34.4% at 10 years, and 8.5% at 15 years. At 15 years, 75.2% of Stage T1a,b patients, 41.5% of Stage T2a,b patients, 21.7% of Stage T3 patients, and 8.5% of Stage T,N1,M0 patients remained free of local recurrence and distant metastases. The elevation of prostatic acid phosphatase prior to radiotherapy was an unfavorable prognostic factor, with impact on both loco-regional recurrences and survival. Conclusions: The external beam radiotherapy for localized carcinoma of the prostate produced a good loco-regional control, NED, and overall survival. Patients with smaller tumors and low grade fared better than the ones with more aggressive and/or bulky tumors. The weakness of this study is the absence of serial prostate-specific measurements, which were not available during the period under study. The complication rate requiring surgical intervention was low, i.e. 0.4%

Lei nº 2.880, de 4 de abril de 1963 | Decreto 4.846, de 25 de setembro de 1967

Directory of Open Access Journals (Sweden)

Marta Maria Araujo

2018-04-01

Full Text Available Nos governos de Aluizio Alves (1961-1966 e de Monsenhor Walfredo Gurgel (1966-1971, respectivamente, no Estado do Rio Grande do Norte, foram criados o Instituto “Padre Miguelinho” (1963 e o Colégio Estadual “Winston Churchill” (1967 na capital Natal. O Instituto “Padre Miguelinho abrangia quatro unidades educacionais: Jardim de Infância “Professor Anfilóquio Câmara”; Grupo Escolar “Professor Luís Soares”; Colégio Estadual do Alecrim e o Ginásio Industrial. O Colégio Estadual “Winston Churchill” compreendia o Ensino Médio com o 1° e 2° ciclos (ginasial e colegial. Nesta Seção de Documento da Revista Educação em Questão, o Conselho Editorial publica a Lei n° 2.880, de 4 de abril de 1963, que criou o Instituto “Padre Miguelinho e o Decreto n° 4.846, de 25 de setembro de 1967, que criou o Colégio Estadual “Winston Churchill”, para fins de estudo e pesquisa de Historiadores da Educação.

Understanding Robert Lucas (1967-1981: his influence and influences

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Alexandre F.S. Andrada

2017-05-01

Full Text Available This paper analyzes Robert Lucas's contribution to economic theory between 1967 (year of his first solo publication and 1981 (the year before the emergence of Real Business Cycle approach, and it has two parts. The first one, using citation data from three different sources, we try to answer two questions: (i What are Lucas's most influential papers currently? (ii How has this influence changed through time? We show, for instance, that according to two of those three sources, Lucas's most influential paper today is not from his business cycle research agenda, which gave him his Nobel Prize in 1995. Moreover, it is clear the loss of influence of Lucas's macroeconomic theory since the early 1980s. In the second part, by cataloging all the works that Lucas had used as bibliographical references in his papers and separating them in two categories (positive and negative, we try to understand who exerted influence on him. We show that the author that Lucas most cited in a positive context were John Muth, Milton Friedman and Edmund Phelps. The authors more often cited in a negative context were John M. Keynes and A. W. Phillips. We discuss the reasons behind this data.

The reliability and validity of a soccer-specific nonmotorised treadmill simulation (intermittent soccer performance test).

Science.gov (United States)

Aldous, Jeffrey W F; Akubat, Ibrahim; Chrismas, Bryna C R; Watkins, Samuel L; Mauger, Alexis R; Midgley, Adrian W; Abt, Grant; Taylor, Lee

2014-07-01

This study investigated the reliability and validity of a novel nonmotorised treadmill (NMT)-based soccer simulation using a novel activity category called a "variable run" to quantify fatigue during high-speed running. Twelve male University soccer players completed 3 familiarization sessions and 1 peak speed assessment before completing the intermittent soccer performance test (iSPT) twice. The 2 iSPTs were separated by 6-10 days. The total distance, sprint distance, and high-speed running distance (HSD) were 8,968 ± 430 m, 980 ± 75 m and 2,122 ± 140 m, respectively. No significant difference (p > 0.05) was found between repeated trials of the iSPT for all physiological and performance variables. Reliability measures between iSPT1 and iSPT2 showed good agreement (coefficient of variation: 0.80). Furthermore, the variable run phase showed HSD significantly decreased (p ≤ 0.05) in the last 15 minutes (89 ± 6 m) compared with the first 15 minutes (85 ± 7 m), quantifying decrements in high-speed exercise compared with the previous literature. This study validates the iSPT as a NMT-based soccer simulation compared with the previous match-play data and is a reliable tool for assessing and monitoring physiological and performance variables in soccer players. The iSPT could be used in a number of ways including player rehabilitation, understanding the efficacy of nutritional interventions, and also the quantification of environmentally mediated decrements on soccer-specific performance.

Monitoring Bare Soil Freeze–Thaw Process Using GPS-Interferometric Reflectometry: Simulation and Validation

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Xuerui Wu

2017-12-01

Full Text Available Frozen soil and permafrost affect ecosystem diversity and productivity as well as global energy and water cycles. Although some space-based Radar techniques or ground-based sensors can monitor frozen soil and permafrost variations, there are some shortcomings and challenges. For the first time, we use GPS-Interferometric Reflectometry (GPS-IR to monitor and investigate the bare soil freeze–thaw process as a new remote sensing tool. The mixed-texture permittivity models are employed to calculate the frozen and thawed soil permittivities. When the soil freeze/thaw process occurs, there is an abrupt change in the soil permittivity, which will result in soil scattering variations. The corresponding theoretical simulation results from the forward GPS multipath simulator show variations of GPS multipath observables. As for the in-situ measurements, virtual bistatic radar is employed to simplify the analysis. Within the GPS-IR spatial resolution, one SNOTEL site (ID 958 and one corresponding PBO (plate boundary observatory GPS site (AB33 are used for analysis. In 2011, two representative days (frozen soil on Doy of Year (DOY 318 and thawed soil on DOY 322 show the SNR changes of phase and amplitude. The GPS site and the corresponding SNOTEL site in four different years are analyzed for comparisons. When the soil freeze/thaw process occurred and no confounding snow depth and soil moisture effects existed, it exhibited a good absolute correlation (|R| = 0.72 in 2009, |R| = 0.902 in 2012, |R| = 0.646 in 2013, and |R| = 0.7017 in 2014 with the average detrended SNR data. Our theoretical simulation and experimental results demonstrate that GPS-IR has potential for monitoring the bare soil temperature during the soil freeze–thaw process, while more test works should be done in the future. GNSS-R polarimetry is also discussed as an option for detection. More retrieval work about elevation and polarization combinations are the focus of future development.

Study of astrophysically important resonant states in 30 S using the 32S(p,t30 S reaction

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Wrede C.

2010-03-01

Full Text Available A small fraction (< 1% of presolar SiC grains is suggested to have been formed in the ejecta of classical novae. The 29P(p,γ30S reaction plays an important role in understanding the Si isotopic abundances in such grains, which in turn provide us with information on the nature of the probable white dwarf progenitor’s core, as well as the peak temperatures achieved during nova outbursts, and thus the nova nucleosynthetic path. The 29P(p,γ30S reaction rate at nova temperatures is determined by two low-lying 3+ and 2+ resonances above the proton threshold at 4399 keV in 30S. Despite several experimental studies in the past, however, only one of these two states has only been observed very recently. We have studied the 30S nuclear structure via the 32S(p,t 30S reaction at 5 laboratory angles between 9° to 62°. We have observed 14 states, eleven of which are above the proton threshold, including two levels at 4692.7 ± 4.5 keV and 4813.8 ± 3.4 keV that are candidates for the 3+ and the previously “issing” 2+ state, respectively.

Chemical, temperature and other data from MIKHAIL SOMOV and PROFESSOR VIZE in the Southern Oceans from 13 December 1967 to 12 March 1987 (NODC Accession 0000234)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Chemical, temperature, and other data were collected from the PROFESSOR VIZE and MIKHAIL SOMOV in the Southern Oceans from December 12, 1967 to March 12, 1987. Data...

The incidence and features of systemic reactions to skin prick tests.

Science.gov (United States)

Sellaturay, Priya; Nasser, Shuaib; Ewan, Pamela

2015-09-01

Skin prick testing (SPT) has been regarded as a safe procedure with few systemic reactions. To evaluate the rate of systemic reactions and their associations after SPT in the largest population to date. In this study reactions were recorded prospectively in a specialist UK allergy clinic for 6 years (2007-2013). An estimated 31,000 patients underwent SPT. Twenty-four patients (age range 7 months to 56 years, mean 23.5 years, 17 female patients, 12 with asthma) had systemic reactions. The rate of systemic reactions to SPT was 0.077%. The likely allergens causing the reaction were foods (18; peanut, 7; walnut, 1; Brazil nut, 2; pistachio, 1; lupin, 1; cow's milk, 2; shrimp, 1; spinach, 1; legume, 1; soy, 1), aeroallergens (4; rabbit, 1; rat, 1; ragwort, 1; grass pollen, 1), wasp venom (1), and Tazocin (1). The causative SPT wheal was larger than 8 mm in 75%. The reaction to Tazocin was severe, with anaphylaxis occurring minutes after SPT. Reactions were treated immediately in the clinic and did not require further medical care. In this largest single-center study, the rate of systemic reactions after SPT was 77 per 100,000 patients. It is the first study to identify foods as a common and important cause (75%), with nuts posing the highest risk. This study reports the first systemic reaction to venom SPT and the first anaphylactic reaction after drug SPT. There was an association with a history of severe reactions and large skin test reaction. There are risks, albeit small, when undertaking SPT. Copyright © 2015 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

The significance of pancreatic juice trace-element concentration in chronic pancreatitis

International Nuclear Information System (INIS)

Persigehl, M.; Loeffler, A.; Hoeck, A.

1979-01-01

The diagnosis of exocrine pancreas insufficiency in patients with chronic pancreatitis is still not easy. The best-suited method to confirm the diagnosis seems to be the secretin pancreozymin test (SPT). As previous results have shown, the determination of trace elements in the pancreatic juice can improve the diagnostic value of the SPT. During the SPT, the concentrations of Zn, Fe, Rb, Co, Cr, Se, Sb, Cs, Sc and Ag were measured in the duodenal aspirate of 50 patients by instrumental neutron activation analysis. Of the 50 patients, 24 suffered from pancreatic insufficiency in chronic pancreatitis and 26 had no signs of pancreatic insufficiency. Only the concentration of zinc differed significantly in the two groups; the other elements showed a similar behaviour. In patients without disease of the exocrine pancreas the zinc content of the pancreatic juice during the SPT ws 0.46+-0.13μg/ml, whereas in patients with pancreatic insufficiency it was only 0.18+-0.07μg/ml. The corresponding output was 171+-49.3μg zinc in controls and 41+-17.4μg in patients. After stimulation with pancreozymin the concentrations of zinc increased in normal patients to 1.13+-0.14μg/ml and to 0.22+-0.12μg/ml in patients with pancreatic insufficiency. The data demonstrate that the measurement of zinc in the duodenal juice during the SPT improves the diagnostic value of the test and that zinc should also be determined in doubtful cases of pancreatic insufficiency. (author)

[Clinical investigation of basophil activation test as a complementary test for house dust mite allergen].

Science.gov (United States)

Ren, H L; Li, J D; Miao, Y H; Xu, T

2018-03-01

Objective: To investigate the clinical application of glass micro fiber basophil activation test (BAT) used as a complementary test for house dust mite allergen. Method: Forty patients with clinical diagnosed allergic rhinitis was test by three methods for house dust mite allergen, skin prick test(SPT),Immuno CAP sIgE, and BAT in vitro. The sensitivity and specificity of glass micro fiber were accessed, and the consistency between BAT, SPT, and Immuno sIgE was analyzed. As in vivo provocation was not performed, gold standard is regarded as the combination of medical history and positive reports of SPT and/or ImmunoCAP sIgE test. Result: Twentythree patients are diagnosed as house dust mite allergic rhinitis by gold standard. The sensitivity and specificity of glass micro fiber BAT were 60.9% and 88.2%, the sensitivity of SPT and sIgE was 87.0% and sIgE 73.9%. The correlation rates between BAT with SPT is 0.67( P house dust mite allergic rhinitis, BAT have a good consistency with SPT and sIgE, while as it has only moderate consistency with "gold standard", further studies are needed to prove its clinical significance. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.

Non-Maxwellian electron energy probability functions in the plume of a SPT-100 Hall thruster

Science.gov (United States)

Giono, G.; Gudmundsson, J. T.; Ivchenko, N.; Mazouffre, S.; Dannenmayer, K.; Loubère, D.; Popelier, L.; Merino, M.; Olentšenko, G.

2018-01-01

We present measurements of the electron density, the effective electron temperature, the plasma potential, and the electron energy probability function (EEPF) in the plume of a 1.5 kW-class SPT-100 Hall thruster, derived from cylindrical Langmuir probe measurements. The measurements were taken on the plume axis at distances between 550 and 1550 mm from the thruster exit plane, and at different angles from the plume axis at 550 mm for three operating points of the thruster, characterized by different discharge voltages and mass flow rates. The bulk of the electron population can be approximated as a Maxwellian distribution, but the measured distributions were seen to decline faster at higher energy. The measured EEPFs were best modelled with a general EEPF with an exponent α between 1.2 and 1.5, and their axial and angular characteristics were studied for the different operating points of the thruster. As a result, the exponent α from the fitted distribution was seen to be almost constant as a function of the axial distance along the plume, as well as across the angles. However, the exponent α was seen to be affected by the mass flow rate, suggesting a possible relationship with the collision rate, especially close to the thruster exit. The ratio of the specific heats, the γ factor, between the measured plasma parameters was found to be lower than the adiabatic value of 5/3 for each of the thruster settings, indicating the existence of non-trivial kinetic heat fluxes in the near collisionless plume. These results are intended to be used as input and/or testing properties for plume expansion models in further work.

Patriot Advanced Capability-3 Missile Segment Enhancement (PAC-3 MSE)

Science.gov (United States)

2015-12-01

Patriot Conduct of Fire Trainer PoP - Proof of Principle T - Threshold TADiL-J - Tactical Digital Information Link-Joint TADSS - Training Aids, Devices...Production Estimate Econ Qty Sch Eng Est Oth Spt Total 5.272 0.311 0.411 0.398 0.000 0.126 0.000 -0.158 1.088 6.360 Current SAR Baseline to Current...Development Estimate Changes APUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total 4.957 0.287 0.286 0.398 0.000 -0.244 0.000 -0.158 0.569 5.526

Radiation cytogentics of the yellow-fever mosquito Aedes aegypti and the plant genus Collinsia. Final report, April 1967--September 1977

Energy Technology Data Exchange (ETDEWEB)

Rai, K.S.

1977-01-01

The major objectives of the project on Aedes aegypti, which is one of the most important disease vectors of man, were to study the cytogenetic effects of radiation and certain chemical mutagens, the genetics of radiation-induced chromosomal rearrangements with particular attention to reciprocal translocations, and the possibility of using translocations for genetic control of natural populations. Results reported on work done during the years 1967 and 1977 show these objectives have been mostly accomplished.

Radiation cytogenetics of the yellow-fever mosquito Aedes aegypti and the plant genus Collinsia. Final report, April 1967--September 1977

International Nuclear Information System (INIS)

Rai, K.S.

1977-01-01

The major objectives of the project on Aedes aegypti, which is one of the most important disease vectors of man, were to study the cytogenetic effects of radiation and certain chemical mutagens, the genetics of radiation-induced chromosomal rearrangements with particular attention to reciprocal translocations, and the possibility of using translocations for genetic control of natural populations. Results reported on work done during the years 1967 and 1977 show these objectives have been mostly accomplished

Multivariate genetic analysis of atopy phenotypes in a selected sample of twins

DEFF Research Database (Denmark)

Thomsen, S F; Ulrik, C S; Kyvik, K O

2006-01-01

traits were estimated and latent factor models of genetic and environmental effects were fitted to the observed data using maximum likelihood methods. RESULTS: The various phenotypic correlations between wheeze, rhinitis, AHR and posSPT were all significant and ranged between 0.50 and 0.86. Traits......BACKGROUND: Atopic traits often co-occur and this can potentially be caused by common aetiological relationships between traits, i.e. a common genetic or a common environmental background. OBJECTIVE: To estimate to what extent the same genetic and environmental factors influence wheeze, rhinitis...... that showed highest genetic correlations were wheeze-rhinitis (rho(A)=0.95), wheeze-AHR (rho(A)=0.85) and rhinitis-posSPT (rho(A)=0.92), whereas lower genetic correlations were observed for rhinitis-AHR (rho(A)=0.43) and AHR-posSPT (rho(A)=0.59). Traits with a high degree of environmental sharing were...

The Image of the 1967 War in Israeli History Textbooks as Test Case: Studying an Active Past in a Protracted Regional Conflict

Science.gov (United States)

Yogev, Esther

2012-01-01

This article seeks to shed light on the dilemma facing history education in regions beset by a protracted, and as yet unresolved ethno-political conflict. The article will examine this issue by means of a unique test case that observes a dramatic war event in Israeli textbooks. The event in question is the Six-Day War of 1967 and the study of its…

MAPS OF THE MAGELLANIC CLOUDS FROM COMBINED SOUTH POLE TELESCOPE AND PLANCK DATA

Energy Technology Data Exchange (ETDEWEB)

Crawford, T. M.; Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Crites, A. T.; Hou, Z.; Keisler, R. [Kavli Institute for Cosmological Physics, University of Chicago, Chicago, IL 60637 (United States); Chown, R.; Holder, G. P.; Haan, T. de; Dobbs, M. A. [Department of Physics, McGill University, Montreal, Quebec H3A 2T8 (Canada); Aird, K. A.; Hrubes, J. D. [University of Chicago, Chicago, IL 60637 (United States); Cho, H-M. [SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, CA 94025 (United States); George, E. M.; Harrington, N. L.; Holzapfel, W. L. [Department of Physics, University of California, Berkeley, CA 94720 (United States); Halverson, N. W. [Department of Astrophysical and Planetary Sciences and Department of Physics, University of Colorado, Boulder, CO 80309 (United States); Knox, L., E-mail: tcrawfor@kicp.uchicago.edu [Department of Physics, University of California, Davis, CA 95616 (United States); and others

2016-12-01

We present maps of the Large and Small Magellanic Clouds from combined South Pole Telescope (SPT) and Planck data. The Planck satellite observes in nine bands, while the SPT data used in this work were taken with the three-band SPT-SZ camera, The SPT-SZ bands correspond closely to three of the nine Planck bands, namely those centered at 1.4, 2.1, and 3.0 mm. The angular resolution of the Planck data ranges from 5 to 10 arcmin, while the SPT resolution ranges from 1.0 to 1.7 arcmin. The combined maps take advantage of the high resolution of the SPT data and the long-timescale stability of the space-based Planck observations to deliver robust brightness measurements on scales from the size of the maps down to ∼1 arcmin. In each band, we first calibrate and color-correct the SPT data to match the Planck data, then we use noise estimates from each instrument and knowledge of each instrument’s beam to make the inverse-variance-weighted combination of the two instruments’ data as a function of angular scale. We create maps assuming a range of underlying emission spectra and at a range of final resolutions. We perform several consistency tests on the combined maps and estimate the expected noise in measurements of features in them. We compare maps from this work to those from the Herschel HERITAGE survey, finding general consistency between the data sets. All data products described in this paper are available for download from the NASA Legacy Archive for Microwave Background Data Analysis server.

Standards of Practice for West African Libraries; Proceedings of a Seminar Held at the Institute of Librarianship, University of Ibadan, 15-16 April 1967.

Science.gov (United States)

Dean, John, Ed.

A seminar on standards for libraries in West Africa was held in April 1967. This proceedings volume presents the papers given by each of the participants. Discussed are the standards for collections, facilities, staff, technical processes and services for public, school, university and special libraries. The purpose was to focus upon the nature,…

Cancer incidence in Mormons and non-Mormons in Utah during 1967--75.

Science.gov (United States)

Lyon, J L; Gardner, J W; West, D W

1980-11-01

Data from the Utah Cancer Registry were used to compare cancer incidence in Mormons and non-Mormons in Utah for the period 1967--75. Church membership was identified for 97.8% of the 20,379 cases in Utah by a search of the central membership files of the Church of Jesus Christ of Latter-Day Saints (or Mormon Church). Sites associated with smoking (lung, larynx, pharynx, oral cavity, esophagus, and urinary bladder) showed an incidence in Mormons at about one-half that of non-Mormons. Rates of cancers of the breast, cervix, and ovary were low in Mormon women; the rate for cervical cancer was about one-half of that observed in non-Mormons. Cancers of the stomach, colon-rectum, and pancreas were about one-third lower in Mormons than in others who are not members of this religious group. Most of the differences seen in cancer incidence can be explained by Mormon teachings regarding sexual activity and alcohol and tobacco use, but some differences (e.g., colon and stomach) remain unexplained.

A peste no nordeste oriental do Brasil e sua fitofisionomia geográfica no período de 1935-1967

Directory of Open Access Journals (Sweden)

Dalva A. Mello

1969-01-01

Full Text Available Neste trabalho foram realizados estudos sôbre a distribuição da peste no Nordeste Oriental do Brasil, relacionando-se esta endemia com as zonas fitofisionômicas. Os dados aqui utilizados foram acumulados do período de 1935 a 1967. O autor faz ainda considerações sôbre a teoria da focalidade e conclui que a peste, dentro do conceito ecológico, deve ser considerada como uma doença euritópica.

Oral desensitization in children with immunoglobulin E-mediated cow's milk allergy--follow-up at 4 yr and 8 months.

Science.gov (United States)

Meglio, Paolo; Giampietro, Paolo G; Gianni, Simona; Galli, Elena

2008-08-01

Until now, the basic treatment for food allergy has been to avoid the offending item. This approach is difficult in the case of common foods and in the case where there is a risk of severe reaction after consuming the offending food, even inadvertently. This is the follow-up of a previous study aimed at desensitizing 21 children with immunoglobulin E (IgE)-mediated cow's milk (CM) allergy. This protocol was totally or partially successful in 85% of cases, but failed in the remaining 15%. Our aims were to study the long-term effectiveness and safety of oral CM desensitization, and the prognostic value of Skin Prick Test (SPT) and specific serum CM IgE. The 21 children were called back (one dropped out). The allergic history and other information on CM intake over the last 4-5 yr were recorded. Children underwent SPT, and end-point SPT, with casein and alpha-lactoalbumin. Specific CM IgE was also measured. At follow-up, 14/20 children totally (n = 13, 65%) or partially (n = 1, 5%) tolerated CM. None of the recalled children reported use of emergency care. SPT positivity to casein and/or alpha-lactoalbumin decreased significantly (p < 0.01), and all the negative SPT referred to the tolerant children. Cutaneous sensitivity to both casein and alpha-lactoalbumin (end-point SPT) significantly decreased after the 6-month desensitization period of the previous study (p < 0.001), but did not decrease significantly at follow-up. A significant reduction of serum-specific CM IgE was also observed (p < 0.05). Clinical tolerance induced by oral CM desensitization persists in time. Negativization of SPT and reduction of specific CM IgE could be considered prognostic indicators of CM tolerance. Oral CM desensitization seems to be a promising method to treat CM food allergy. This protocol is time-consuming but offers the advantage that it can be performed at home. This methodology must only be used by trained staff.

Convergence of lateral dynamic measurements in the plasma membrane of live cells from single particle tracking and STED-FCS

International Nuclear Information System (INIS)

Lagerholm, B Christoffer; Eggeling, Christian; Andrade, Débora M; Clausen, Mathias P

2017-01-01

Fluorescence correlation spectroscopy (FCS) in combination with the super-resolution imaging method STED (STED-FCS), and single-particle tracking (SPT) are able to directly probe the lateral dynamics of lipids and proteins in the plasma membrane of live cells at spatial scales much below the diffraction limit of conventional microscopy. However, a major disparity in interpretation of data from SPT and STED-FCS remains, namely the proposed existence of a very fast (unhindered) lateral diffusion coefficient, ⩾5 µ m 2 s −1 , in the plasma membrane of live cells at very short length scales, ≈⩽ 100 nm, and time scales, ≈1–10 ms. This fast diffusion coefficient has been advocated in several high-speed SPT studies, for lipids and membrane proteins alike, but the equivalent has not been detected in STED-FCS measurements. Resolving this ambiguity is important because the assessment of membrane dynamics currently relies heavily on SPT for the determination of heterogeneous diffusion. A possible systematic error in this approach would thus have vast implications in this field. To address this, we have re-visited the analysis procedure for SPT data with an emphasis on the measurement errors and the effect that these errors have on the measurement outputs. We subsequently demonstrate that STED-FCS and SPT data, following careful consideration of the experimental errors of the SPT data, converge to a common interpretation which for the case of a diffusing phospholipid analogue in the plasma membrane of live mouse embryo fibroblasts results in an unhindered, intra-compartment, diffusion coefficient of  ≈0.7–1.0 µ m 2 s −1 , and a compartment size of about 100–150 nm. (topical review)

Et lykkeligt fornuftsægteskab? Turistforeningen for Danmark mellem hjemstavnsturisme og eksportturisme ca. 1888-1967

Directory of Open Access Journals (Sweden)

Mikael Frausing

2010-11-01

Full Text Available Artiklen baserer sig på undersøgelser af Turistforeningen for Danmarks virke med hovedvægt på perioden 1923-1945. Nedsættelsen af „Udenrigsministeriets Udvalg for Turistpropaganda i Udlandet" i 1934 betød en gennemgribende forandring, hvor staten for første gang involverede sig aktivt i Turistforeningens organisationog arbejde. Turisme blev herved i højere grad opfattet som et eksporterhverv og indrettet efter sit økonomiske indtjeningspotentiale. Hermed lagdes grunden til den organisation og den turismeopfattelse, som kom til at dominere efterkrigstidens danske turisme, mens tidligere, konkurrerende syn på turismen på sigt marginaliseredes. En gennemgang af Turistforeningens brochurer og udgivelservil i øvrigt demonstrere, at „Danmark som turistland" repræsenteredes i meget forskellige og konkurrerende diskurser, lige fra en hjemstavnsorientering med vægt på oldtid, landskaber og landbokultur til det „moderne Danmark" med levende byliv, uhøjtidelig harmoni, ungdommelighed og social ansvarlighed. Overordnet betød mellemkrigstiden både i organisation og repræsentation en forskydning af turistarbejdet fra provinsens lokale, folkelige forankring til byernes, primært københavnske, erhvervsinteresser.Abstract: A Happy Marriage of Convenience?The Danish National Tourist Organization c.1888-1967Turistforeningen for Danmark was the Danish National Tourist Organization from 1923-1967. It replaced Den danske Turistforening which dissolved in the turmoil following World War I, and was itself replaced in 1967 by Danmarks Turistråd. This article offers an outline of the development of Turistforeningen for Danmark with a main focus on the interwar-period 1923-1939. Through an analysis of the organization's activities to attract foreign visitors as well as to„enhance"the travel of Danes within their own country it is shown, how two distinct understandings of „tourism" co-existed, and was balanced against each other, within the

Constraints on the Richness-Mass Relation and the Optical-SZE Positional Offset Distribution for SZE-Selected Clusters

CERN Document Server

Saro, A; Rozo, E; Benson, B A; Mohr, J; Rykoff, E S; Soares-Santos, M; Bleem, L; Dodelson, S; Melchior, P; Sobreira, F; Upadhyay, V; Weller, J; Abbott, T; Abdalla, F B; Allam, S; Armstrong, R; Banerji, M; Bauer, A H; Bayliss, M; Benoit-Lévy, A; Bernstein, G M; Bertin, E; Brodwin, M; Brooks, D; Buckley-Geer, E; Burke, D L; Carlstrom, J E; Capasso, R; Capozzi, D; Carnero Rosell, A; Carrasco Kind, M; Chiu, I; Covarrubias, R; Crawford, T M; Crocce, M; D'Andrea, C B; da Costa, L N; DePoy, D L; Desai, S; de Haan, T; Diehl, H T; Dietrich, J P; Doel, P; Cunha, C E; Eifler, T F; Evrard, A E; Fausti Neto, A; Fernandez, E; Flaugher, B; Fosalba, P; Frieman, J; Gangkofner, C; Gaztanaga, E; Gerdes, D; Gruen, D; Gruendl, R A; Gupta, N; Hennig, C; Holzapfel, W L; Honscheid, K; Jain, B; James, D; Kuehn, K; Kuropatkin, N; Lahav, O; Li, T S; Lin, H; Maia, M A G; March, M; Marshall, J L; Martini, Paul; McDonald, M; Miller, C J; Miquel, R; Nord, B; Ogando, R; Plazas, A A; Reichardt, C L; Romer, A K; Roodman, A; Sako, M; Sanchez, E; Schubnell, M; Sevilla, I; Smith, R C; Stalder, B; Stark, A A; Strazzullo, V; Suchyta, E; Swanson, M E C; Tarle, G; Thaler, J; Thomas, D; Tucker, D; Vikram, V; von der Linden, A; Walker, A R; Wechsler, R H; Wester, W; Zenteno, A; Ziegler, K E

2015-01-01

We cross-match galaxy cluster candidates selected via their Sunyaev-Zel'dovich effect (SZE) signatures in 129.1 deg$^2$ of the South Pole Telescope 2500d SPT-SZ survey with optically identified clusters selected from the Dark Energy Survey (DES) science verification data. We identify 25 clusters between $0.1\\lesssim z\\lesssim 0.8$ in the union of the SPT-SZ and redMaPPer (RM) samples. RM is an optical cluster finding algorithm that also returns a richness estimate for each cluster. We model the richness $\\lambda$-mass relation with the following function $\\langle\\ln\\lambda|M_{500}\\rangle\\propto B_\\lambda\\ln M_{500}+C_\\lambda\\ln E(z)$ and use SPT-SZ cluster masses and RM richnesses $\\lambda$ to constrain the parameters. We find $B_\\lambda= 1.14^{+0.21}_{-0.18}$ and $C_\\lambda=0.73^{+0.77}_{-0.75}$. The associated scatter in mass at fixed richness is $\\sigma_{\\ln M|\\lambda} = 0.18^{+0.08}_{-0.05}$ at a characteristic richness $\\lambda=70$. We demonstrate that our model provides an adequate description of the ma...

Changing the cubic ferrimagnetic domain structure in temperature region of spin flip transition

International Nuclear Information System (INIS)

Djuraev, D.R.; Niyazov, L.N.; Saidov, K.S.; Sokolov, B.Yu.

2011-01-01

The transformation of cubic ferrimagnetic Tb 0.2 Y 2.8 Fe 5 O 12 domain structure has been studied by magneto optic method in the temperature region of spontaneous spin flip phase transition (SPT). It has been found that SPT occurs in a finite temperature interval where the coexistence of low- and high- temperature magnetic phase domains has observed. A character of domain structure evolution in temperature region of spin flip essentially depends on the presence of mechanical stresses in crystal. Interpretation of experimental results has been carried out within the framework of SPT theory for a cubic crystal. (authors)

Enciclopédia para formar leitores: A cultura na gênese do Caderno de Sábado do Correio do Povo (Porto Alegre, 1967-1969

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Everton Terres Cardoso

2010-02-01

Full Text Available O Caderno de Sábado, suplemento cultural do Correio do Povo, circulou de setembro de 1967 a janeiro de 1981 em Porto Alegre. O presente artigo discute como se configura a noção de cultura na gênese do suplemento (1967-1969, considerando seu caráter enciclopédico e a proposta de formar culturalmente o leitor. A Análise de Conteúdo das 111 primeiras edições possibilitou a observação do ecletismo temático; do equilíbrio entre o universal e local; da alternância entre memória e atualidade; e da participação do Caderno de Sábado na constituição dos campos intelectual, acadêmico e artístico locais. O veículo traduzia duas acepções do termo cultura: o ideal iluminista de formação pelo jornalismo e a noção romântica alemã de elevação do espírito por meio da proximidade com as letras, artes e humanidades.

The SPT+Herschel+ALMA+Spitzer Legacy Survey: The stellar content of high redshift strongly lensed systems

Science.gov (United States)

Vieira, Joaquin; Ashby, Matt; Carlstrom, John; Chapman, Scott; DeBreuck, Carlos; Fassnacht, Chris; Gonzalez, Anthony; Phadke, Kedar; Marrone, Dan; Malkan, Matt; Reuter, Cassie; Rotermund, Kaja; Spilker, Justin; Weiss, Axel

2018-05-01

The South Pole Telescope (SPT) has systematically identified 90 high-redshift strongly gravitationally lensed submillimeter galaxies (SMGs) in a 2500 square-degree cosmological survey of the millimeter (mm) sky. These sources are selected by their extreme mm flux, which is largely independent of redshift and lensing configuration. We are undertaking a comprehensive and systematic followup campaign to use these "cosmic magnifying glasses" to study the infrared background in unprecedented detail, inform the condition of the interstellar medium in starburst galaxies at high redshift, and place limits on dark matter substructure. Here we ask for 115.4 hours of deep Spitzer/IRAC imaging to complete our survey of 90 systems to a uniform depth of 30min integrations at 3.6um and 60min at 4.5um. In our sample of 90 systems, 16 have already been fully observed, 30 have been partially observed, and 44 have not been observed at all. Our immediate goals are to: 1) constrain the specific star formation rates of the background high-redshift submillimeter galaxies by combining these Spitzer observations with our APEX, Herschel, and ALMA data, 2) robustly determine the stellar masses and mass-to-light ratios of all the foreground lensing galaxies in the sample by combining these observations with our VLT and Gemini data, the Dark Energy Survey, and ALMA; and 3) provide complete, deep, and uniform NIR coverage of our entire sample of lensed systems to characterize the environments of high redshift SMGs, maximize the discovery potential for additional spectacular and rare sources, and prepare for JWST. This program will provide the cornerstone data set for two PhD theses: Kedar Phadke at Illinois will lead the analysis of stellar masses for the background SMGs, and Kaja Rotermund at Dalhousie will lead the analysis of stellar masses for the foreground lenses.

[The source and factors that influence tracheal pulse oximetry signal].

Science.gov (United States)

Fan, Xiao-hua; Wei, Wei; Wang, Jian; Mu, Ling; Wang, Li

2010-03-01

To investigate the source and factors that influence tracheal pulse oximetry signal. The adult mongrel dog was intubated after anesthesia. The tracheal tube was modified by attaching a disposable pediatric pulse oximeter to the cuff. The chest of the dog was cut open and a red light from the tracheal oximeter was aligned with the deeper artery. The changes in tracheal pulse oxygen saturation (SptO2) signal were observed after the deeper artery was blocked temporarily. The photoplethysmography (PPG) and readings were recorded at different intracuff pressures. The influence of mechanical ventilation on the signal was also tested and compared with pulse oxygen saturation (SpO2). The SptO2 signal disappeared after deeper artery was blocked. The SptO2 signal changed with different intracuff pressures (P signal appeared under 20-60 cm H2O of intracuff pressure than under 0-10 cm H2O of intracuff pressure(P signal under a condition with mechanical ventilation differed from that without mechanical ventilation (P signal is primarily derived from deeper arteries around the trachea, not from the tracheal wall. Both intracuff pressures and mechanical ventilation can influence SptO2 signal. The SptO2 signal under 20-60 cm H2O of intracuff pressure is stronger than that under 0-10 em H2O of intracuff pressure. Mechanical ventilation mainly changes PPG.

Influence of low-intensity laser therapy on spatial perception threshold and electroneurographic finding in patients with diabetic polyneuropathy

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Perić Zoran

2007-01-01

Full Text Available Introduction: Low-intensity laser therapy (LILT can be applied in cases when patients with diabetic polyneuropathy (DPN suffer from chronic severe neuropathic pain. Objective. We wanted to analyze influence of LILT on spatial perception threshold (SPT and electroneurographic (ENG parameters in patients with painful DPN. Method. We analyzed 45 patients (25 males, average age 54.3 years (54.3±10.9, with clinical and ENG signs of painful DPN. The patients were divided into two groups: A and B. Group A consisted of 30 patients with DPN who had 30 LILT treatments over the period of 12 weeks and group B consisted of 15 patients with DPN who received only vitamin therapy per os within the same period. Prior to and after 12 weeks of treatment, the following ENG parameters were determined using surface electrodes: motor (MCV and sensory conduction velocities (SCV values (in m/s of nervus (n. peroneus (NP, n. tibialis (NT and n. medianus (NM and their motor distal latency (MDL values (in ms. SPT value (score as number from 1 to 8 was determined with Tactile Circumferential Discriminator on dorsal part of foot’s big toe skin. For statistical analysis, we used Student’s t-test and Pearson correlation (sig. 2 tailed study. Results. We registered statistically significant difference between SPT (p<0.01 values prior to (5.25±1.11 and after (4.87±0.90 LILT, as well as NMMCV (p<0.05 values prior to (47.18±5.08 and after (49.12±3.72 LILT. Besides, we registered, only after LILT, statistically significant correlation between SPT and NMDML (p<0.01 values and also between SPT and NMSCV (p<0.05 values. The differences and correlations between other analyzed parameters before and after treatments were not significant (p>0.05. Conclusion. In this study we registered significant decrease of SPT and increase of NMMCV after LILT and that indicated a favorable effect of this treatment in analyzed patients with painful DPN. In our opinion these results need further

'The televising of science is a process of television': establishing Horizon, 1962-1967.

Science.gov (United States)

Boon, Timothy

2015-03-01

BBC Television's Horizon series, fifty years old on 2 May 2014, despite its significance to the history of the public culture of science, has been little studied. This microhistorical account follows the gestation and early years of the programme, demonstrating how it established a social and cultural account of science. This was a result of televisual factors, notably the determination to follow the format of the successful arts television programme Monitor. It illuminates how the processes of television production, with a handful of key participants - Aubrey Singer, Gerald Leach, Philip Daly, Gordon Rattray Taylor, Ramsay Short, Michael Peacock and Robert Reid - established the format of the programme. This occurred over seventeen months of prior preparation followed by three troubled years of seeking to establish a stable form. This was finally achieved in 1967 when the programme adopted a film documentary approach after extended attempts at making it as a studio-based magazine programme. The story has implications for understanding the social accounts of science that were circulating in the key decade of the 1960s.

Multilocus Sequence Typing of Historical Burkholderia pseudomallei Isolates Collected in Southeast Asia from 1964 to 1967 Provides Insight into the Epidemiology of Melioidosis

OpenAIRE

McCombie, Roberta L.; Finkelstein, Richard A.; Woods, Donald E.

2006-01-01

A collection of 207 historically relevant Burkholderia pseudomallei isolates was analyzed by multilocus sequence typing (MLST). The strain collection contains environmental isolates obtained from a geographical distribution survey of B. pseudomallei isolates in Thailand (1964 to 1967), as well as stock cultures and colony variants from the U.S. Army Medical Research Unit (Malaysia), the Walter Reed Army Institute for Research, and the Pasteur Institute (Vietnam). The 207 isolates of the colle...

A Design of Solar Proton Telescope for Next Generation Small Satellite

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Jongdae Sohn

2012-12-01

Full Text Available The solar proton telescope (SPT is considered as one of the scientific instruments to be installed in instruments for the study of space storm (ISSS which is determined for next generation small satellite-1 (NEXTSat-1. The SPT is the instrument that acquires the information on energetic particles, especially the energy and flux of proton, according to the solar activity in the space radiation environment. We performed the simulation to determine the specification of the SPT using geometry and tracking 4 (GEANT4. The simulation was performed in the range of 0.6-1,000 MeV considering that the proton, which is to be detected, corresponds to the high energy region according to the solar activity in the space radiation environment. By using aluminum as a blocking material and adjusting the energy detection range, we determined total 7 channels (0.6~5, 5~10, 10~20, 20~35, 35~52, 52~72, and >72 MeV for the energy range of SPT. In the SPT, the proton energy was distinguished using linear energy transfer to compare with or discriminate from relativistic electron for the channels P1-P3 which are the range of less than 20 MeV, and above those channels, the energy was determined on the basis of whether silicon semiconductor detector (SSD signal can pass or not. To determine the optimal channel, we performed the conceptual design of payload which uses the SSD. The designed SPT will improve the understanding on the capture and decline of solar energetic particles at the radiation belt by measuring the energetic proton.

Fracionamento densimétrico com politungstato de sódio no estudo da proteção física da matéria orgânica em solos Densimetric fractionation with sodium polytungstate to investigate physical protection of soil organic matter

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Paulo Cesar Conceição

2008-04-01

Full Text Available O fracionamento físico densimétrico é uma técnica que permite estudar a proteção física da matéria orgânica (MO no solo, sendo utilizadas, de forma indistinta, soluções densas de iodeto de sódio (NaI e de politungstato de sódio (PTS. O objetivo deste estudo foi avaliar (a o efeito de soluções de NaI (1,8 g cm-3 e de PTS (1,8, 2,0 e 2,2 g cm-3 no rendimento de carbono (C nas frações leve-livre (FLL e leve-oclusa (FLO da MO na camada de 0-5 cm de um Argissolo Vermelho [PVd, Eldorado do Sul (RS] e de um Latossolo Vermelho [LVdf, Dourados (MS] e (b a magnitude da proteção física da MO em agregados no acúmulo de C orgânico nesses solos submetidos, respectivamente, ao sistema plantio direto por 18 anos (PD e pastagem (Brachiaria decumbens por nove anos, em comparação à sua condição em preparo convencional (PC. Em ambos os locais, blocos indeformados de solo foram coletados em experimentos de longa duração; os agregados foram separados nos planos de fraqueza e passados em peneira de 9,51 mm; esse material foi submetido ao fracionamento densimétrico da MO do solo. O uso da solução de PTS 1,8 g cm-3 aumentou de 176 a 727 % o rendimento de C na FLO em comparação à solução de NaI na mesma densidade, mas não teve efeito no rendimento de C da FLL da MO do solo. O aumento da densidade da solução de PTS de 1,8 g cm-3 para 2,0 g cm-3 incrementou de 30 a 99 % o rendimento de C da FLO; contudo, o aumento da densidade para 2,2 g cm-3 resultou em aumento pouco expressivo (Through the densimetric fractionation it is possible to study the physical protection of soil organic matter (SOM. High density solutions of sodium iodide (NaI or sodium polytungstate (SPT have been indistinctively used for this purpose. This study aimed to assess: (a the capacity of these two solutions at a density of 1.8 g cm-3 (NaI-1.8 and SPT-1.8 and of SPT at densities of 2.0 (SPT-2.0 and 2.2 g cm-3 (SPT-2.2 to increase C recovery in the free light

Cystic fibrosis transmembrane conductance regulator gene mutations: do they play a role in the aetiology of allergic bronchopulmonary aspergillosis?

Science.gov (United States)

Eaton, T E; Weiner Miller, P; Garrett, J E; Cutting, G R

2002-05-01

Previous work suggests that cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations may be implicated in the aetiology of allergic bronchopulmonary aspergilosis (ABPA). To compare the frequency of CF gene mutations in asthmatics with ABPA of varying severity with asthmatics who were skin prick test (SPT)-positive to Aspergillus fumigatus (Af) without evidence of ABPA and asthmatics SPT-negative to Af. Thirty-one Caucasian patients with ABPA were identified, together with asthmatics SPT positive to Af without evidence of ABPA (n = 23) and SPT negative to Af (n = 28). Genomic DNA was tested for 16 CF mutations accounting for approximately 85% of CF alleles in Caucasian New Zealanders. Four (12.9%) ABPA patients were found to be carriers of a CF mutation (DeltaF508 n = 3, R117H n = 1), one (4.3%) asthmatic SPT positive to Af without ABPA (DeltaF508), and one (3.6%) asthmatic SPT negative to Af (R117H). All patients with a CF mutation had normal sweat chloride (< 40 mM). There was no significant difference between the frequency of CF mutations in the ABPA patients and asthmatics without ABPA. However, the frequency of CF mutations in the ABPA patients was significantly different (P = 0.0125) to the expected carrier rate in the general population. These results lend further support to a possible link between CF mutations and ABPA.

CH-47F Improved Cargo Helicopter (CH-47F)

Science.gov (United States)

2015-12-01

Confidence Level Confidence Level of cost estimate for current APB: 50% The Confidence Level of the CH-47F APB cost estimate, which was approved on April...M) Initial PAUC Development Estimate Changes PAUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total 10.316 -0.491 3.003 -0.164 2.273 7.378...SAR Baseline to Current SAR Baseline (TY $M) Initial APUC Development Estimate Changes APUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total

Distribution of inhalant allergies in pediatric patients presenting with allergic complaints in the Eastern Anatolia Region.

Science.gov (United States)

Kilic, Mehmet; Taskin, Erdal

2016-08-01

The objective of this study was to define the distribution of inhalant allergens in pediatric patients in whom sensitization was diagnosed with a skin prick test (SPT) who had presented with allergic complaints. In addition, the correlation between the inhalant allergens detected on the SPT and the patients' demographic features, diagnosis, and laboratory findings was defined. A total of 1415 children among the 4056 patients who presented at a clinic in the Eastern Anatolia region with allergic complaints and who had undergone an SPT were included in this study. On the SPT, sensitization to grass pollens was found in 60.1%, cereals pollens in 57.2%, and Dermatophagoides farinae in 21.8% of the patients. Furthermore, on the SPT, incidence of asthma development was 3.96 times higher (odds ratio 3.96, 95% CI: 1.77-6.83; P=0.001) in patients who were allergic to Dermatophagoides farinae. In our study, differences were found in the study region compared to data from around the world and other regions in Turkey in terms of the distribution of allergies and variations in allergens in patients diagnosed due to variations in climate and plants.

Fifty years of IAA History Symposia (1967-2016)

Science.gov (United States)

Skoog, A. Ingemar; Hall, R. Cargill

2017-05-01

The International Academy of Astronautics (IAA) Symposia on the History of Rocketry and Astronautics have been held annually at the International Astronautical Congresses since 1967. During these past 50 years nearly 800 papers have been presented and subsequently published in the proceedings. With a 20-year rule imposed for historical presentations, the first 10 symposia concentrated on pre-World War II and early 1950s activities. A surprisingly large number of papers on early, less well-known Soviet-Russian contributions to rocketry and astronautics were presented in the first symposia, despite the ongoing Space Race between the U.S and USSR. Another important element in these symposia involved memoir papers offered by pre- and post-war rocket and astronautics pioneers from many countries, and the participation of many of these pioneers in person. In sum, the history of national space and rocket projects from some 40 countries were presented over the years in IAA History Symposia. These 50 symposia have provided a platform for scholars and professional and non-professional historians to meet and discuss the history of rocketry and astronautics, and to personally interview many space pioneers, most of whom today are deceased. Their personal recollections have since been shared with a large audience. Over time, IAA history papers divided into recognizable periods: ancient times through the 19th century, and the 20th and 21st centuries, which separate among actions and events that took place before 1945, in 1945 to 1957, and after 1957 (which marked the beginning of the space age). Proceedings of the IAA History Symposia have been published in English, ultimately in the History Series of the American Astronautical Society (AAS) and its publishing arm, Univelt Inc., under an agreement secured with the IAA. This paper presents an overview of the IAA History Symposia. It examines the early years of the history committee and its first symposium, the evolution of

Digital dermoscopy to determine skin melanin index as an objective indicator of skin pigmentation

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Sara Majewski

2016-04-01

Full Text Available Clinical assessment of skin photosensitivity is subjectively determined by erythema and tanning responses to sunlight recalled by the subject, alternatively known as Fitzpatrick Skin Phototype (SPT. Responses may be unreliable due to recall bias, subjective bias by clinicians and subjects, and lack of cultural sensitivity of the questions. Analysis of red-green-blue (RGB color spacing of digital images may provide an objective determination of SPT. This paper presents the studies to assess the melanin index (MI, as determined by RGB images obtained by both standard digital camera as well as by videodermoscope, and to correlate the MI with SPT based upon subjects’ verbal responses to standardized questions administered by a dermatologist.A sample of subjects representing all SPTs I–VI was selected. Both the digital camera and videodermoscope were calibrated at standard illumination, light source and white balance. Images of constitutive skin of the upper ventral arm were taken of each subject using both instruments.The studies showed that 58 subjects (20 M, 38 F were enrolled in the study (mean age: 47 years; range: 20–89, stratified to skin phototype I–VI. MI obtained by using both digital camera and videodermoscope increased significantly as the SPT increased p = 0.004 and p < 0.0001, respectively and positively correlated with dermatologist-assessed SPT (Spearman correlation, r = 0.48 and r = 0.84, respectively.Digital imaging can quantify melanin content in order to quantitatively approximate skin pigmentation in all skin phototypes including Type VI skin. This methodology holds promise as a simple, non-invasive, rapid and objective approach to reliably determine skin phototype and, with further investigation, may prove to be both practical and useful in the prediction of skin cancer risk.

The Xanthophyceae and Chlorophyceae of the Western Ross Sea, Victoria Land, Antarctica and Macquarie Island collected under the direction of Prof. Dr. J. S. Zaneveld (1963—1967)

NARCIS (Netherlands)

Wagner, H.P.; Zaneveld, J.S.

1988-01-01

During the austral summer seasons of 1963-1964 and 1964-1965, and during the austral winter season of 1967 Prof. Dr. J.S. Zaneveld made collection expeditions to the western Ross Sea. In 1965 collections were also made from the U.S.C.G. icebreaker ‘Glacier’, around the western Ross Sea and around

On the continuing relevance of Mandelbrot's non-ergodic fractional renewal models of 1963 to 1967

Science.gov (United States)

Watkins, Nicholas W.

2017-12-01

The problem of "1/f" noise has been with us for about a century. Because it is so often framed in Fourier spectral language, the most famous solutions have tended to be the stationary long range dependent (LRD) models such as Mandelbrot's fractional Gaussian noise. In view of the increasing importance to physics of non-ergodic fractional renewal models, and their links to the CTRW, I present preliminary results of my research into the history of Mandelbrot's very little known work in that area from 1963 to 1967. I speculate about how the lack of awareness of this work in the physics and statistics communities may have affected the development of complexity science, and I discuss the differences between the Hurst effect, "1/f" noise and LRD, concepts which are often treated as equivalent. Contribution to the "Topical Issue: Continuous Time Random Walk Still Trendy: Fifty-year History, Current State and Outlook", edited by Ryszard Kutner and Jaume Masoliver.

Fertility in Islamic Republic of Iran: Levels, Trends and Differentials during Three Decades (1967-1996

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Kazem Mohammad

2002-12-01

The detailed nature of these data collected for each birth enabled fertility rates to be calculated for exact periods before the survey, for exact calendar years. Higher fertility rates were found for the period 10-15 and 15-20 years preceding the survey. These high fertility levels are probably due to some socio-economic changes in favor of higher level of fertility immediately after the 1979 revolution. However the results of the present survey show during 1967-1996, the TFR1 had dropped from 6.38 to 2.88 (an expected TFR based on fertility behavior during 1992-96. This decline was probably due to delay in marriage and policy changes in favor of population control particularly since 1987. Despite this potential fertility decline in recent years, Iran is expected to face a baby boom as the offspring who were born during the 1976-86 reach to the reproductive age in the coming decades.

Optimising position control of a solar parabolic trough

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Puramanathan Naidoo

2011-03-01

Full Text Available In today’s climate of growing energy needs and increasing environmental concerns, alternatives to the use of non-renewable and polluting fossil fuels have to be investigated. One such alternative is solar energy. This study is based on the implementation of a mathematical computation – the PSA (Plataforma Solar de Almeria computation developed at PSA (the European Test Centre for solar energy applications – embedded in a control algorithm to locate the position of the sun. Tests were conducted on a solar parabolic trough (SPT constructed at the Solar Thermal Applications Research Laboratory of the Mangosuthu University of Technology (Durban, South Africa for optimal position control using the PSA value. The designed control algorithm embedded in an industrial Siemens S7-314 C-2PtP programmable logic controller compared the PSA computation to a measured position of the SPT to optimally rotate the SPT to a desired position with the constant movement of the sun. The two main angles of the sun relative to the position of the SPT on earth, the zenith angle and the azimuth angle, both calculated in the PSA from the vertical and horizontal planes, respectively, were applied to the control algorithm to generate an appropriate final tracking angle within a 0.007 radian (0° 24′ 3.6″ tolerance, in accordance to the construction specifications and solar collector testing standards of the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE, 1991. These values, together with the longitude and latitude applicable to the geographical location of the SPT, were processed in the control software to rotate the SPT to an optimal position with respect to the position of the sun in its daily path, for solar-to-thermal conversion.

Aproximación a la enseñanza secundaria durante el Franquismo (1938-1967

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Leoncio VEGA GIL

2010-03-01

Full Text Available RESUMEN: El trabajo que abordamos en esta monografía se centra cronológicamente en el ciclo histórico conocido como franquismo y a nivel de contenido delimitamos el estudio a la enseñanza secundaria tanto desde su dimensión formal y política, a partir de los pilares legislativos que sobre este nivel se fueron erigiendo (1938, 1953 y 1967, como desde la realidad escolar en términos cuantitativos de la geografía nacional y un estudio interno más profundo de algunas variables para el caso de su articulación en Zamora. Y, si las fuentes nos lo permiten, entraremos en las cuestiones del «tercer nivel», la mentalidad del alumno de segunda enseñanza y su relación con el modelo social y académico real de los alumnos que asisten a cursar estudios en el Instituto «Claudio Moyano» de Zamora o de los que cursan la enseñanza colegiada, tan potenciada esta última ahora por el régimen.

Medical clowns ease anxiety and pain perceived by children undergoing allergy prick skin tests.

Science.gov (United States)

Goldberg, A; Stauber, T; Peleg, O; Hanuka, P; Eshayek, L; Confino-Cohen, R

2014-10-01

Intervention of medical clowns (MC) during various medical procedures performed in children has been used to relieve anxiety and pain. Their role in allergy skin testing has never been evaluated. To evaluate whether MC can diminish pain and anxiety perceived by children undergoing allergy skin prick tests (SPT). In a prospective, randomized, controlled, and blinded study, children undergoing SPT were or were not accompanied by MC. All parents and children ≥8 years completed the State-Trait Anxiety Inventory (STAI) before and after SPT. Videotapes recorded during the procedure were scored for anxiety (m-YPAS) for all children and for pain (FLACC) for children 2-7 years old by a psychologist who was unaware of the MC's presence. After SPT, children ≥8 years completed a visual analog score (VAS) for pain. Ninety-one children (mean age 8.2 years, M/F = 54/37) were recruited of whom 45 were accompanied by clowns. A significant reduction in state-STAI was found in the clowns group, in both parents and children, when compared with the regular group (26.9 ± 6.6 and 32.3 ± 10.0; P = 0.004, and 27.1 ± 4.2 and 34.3 ± 7.6; P = 0.002, respectively). Both m-YPAS and FLACC were reduced in the clowns group compared with the regular one. In the clowns group, m-YPAS positively correlated with both VAS and FLACC (P = 0.000 and 0.002, respectively). m-YPAS was positively correlated with FLACC in the regular group (P = 0.000). Medical clowns significantly decrease the level of anxiety perceived by both children undergoing allergy SPT and their parents, as well as the pain perceived by young children. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Effects of Blocked and Random Practice Schedule on Outcomes of Sound Production Treatment for Acquired Apraxia of Speech: Results of a Group Investigation.

Science.gov (United States)

Wambaugh, Julie L; Nessler, Christina; Wright, Sandra; Mauszycki, Shannon C; DeLong, Catharine; Berggren, Kiera; Bailey, Dallin J

2017-06-22

The purpose of this investigation was to compare the effects of schedule of practice (i.e., blocked vs. random) on outcomes of Sound Production Treatment (SPT; Wambaugh, Kalinyak-Fliszar, West, & Doyle, 1998) for speakers with chronic acquired apraxia of speech and aphasia. A combination of group and single-case experimental designs was used. Twenty participants each received SPT administered with randomized stimuli presentation (SPT-R) and SPT applied with blocked stimuli presentation (SPT-B). Treatment effects were examined with respect to accuracy of articulation as measured in treated and untreated experimental words produced during probes. All participants demonstrated improved articulation of treated items with both practice schedules. Effect sizes were calculated to estimate magnitude of change for treated and untreated items by treatment condition. No significant differences were found for SPT-R and SPT-B relative to effect size. Percent change over the highest baseline performance was also calculated to provide a clinically relevant indication of improvement. Change scores associated with SPT-R were significantly higher than those for SPT-B for treated items but not untreated items. SPT can result in improved articulation regardless of schedule of practice. However, SPT-R may result in greater gains for treated items. https://doi.org/10.23641/asha.5116831.

Summary of seismic activity and its relation to geology and mining in the Sunnyside mining district, Carbon and Emery Counties, Utah, during 1967-1970

Science.gov (United States)

Dunrud, C. Richard; Osterwald, Frank W.; Hernandez, Jerome

1973-01-01

In the Sunnyside mining district, Utah, coal is mined under thick and variable overburden which is locally weakened by faults and other structural discontinuities. Stress changes and local stress concentrations produced by mining under these conditions often cause sudden and violent ruptures in the coal and surrounding rock mass. The strain energy released by this type of failure, which can produce shock waves and may discharge coal and rock with explosive force, is often a serious threat to life and property. These releases of strain energy are called bumps or bounces by miners if they occur in the coal, and rock bursts if they occur in the surrounding rock mass. Many of these releases are so violent that they generate seismic waves that can be felt, or at least detected by seismic instruments, miles from the site of the rupture, whereas others are smaller and can be detected only by those sensitive seismic instruments within a few thousand feet of the site of the rupture. In 1969 and 1970, about 27,000 and about 15,000 earth tremors, respectively, were recorded by the five-station seismic monitoring network that is located at the surface and encompasses most of the mine workings in the district. Of these totals, 512 and 524 earth tremors, respectively, were of sufficient magnitude (greater than 1. 5 on the Richter scale) so that the hypocenters could be accurately located. In 1968 about 20,000 tremors were recorded, with 281 large enough to plot, but in 1967 over 50,000 were recorded, of which 540 were plotted. In this report we discuss the way in which seismic activity, geology, and mining are related or seem to be related for the period 1967 through 1970, with emphasis on the period 1969-70. We also suggest certain mining procedures which, based on studies during the period, might increase the safety and efficiency of mining operations in the Sunnyside district. A complete tabulation of the larger magnitude earth tremors which occurred during 1969-70 and

Consistency relations in effective field theory

Energy Technology Data Exchange (ETDEWEB)

Munshi, Dipak; Regan, Donough, E-mail: D.Munshi@sussex.ac.uk, E-mail: D.Regan@sussex.ac.uk [Astronomy Centre, School of Mathematical and Physical Sciences, University of Sussex, Brighton BN1 9QH (United Kingdom)

2017-06-01

The consistency relations in large scale structure relate the lower-order correlation functions with their higher-order counterparts. They are direct outcome of the underlying symmetries of a dynamical system and can be tested using data from future surveys such as Euclid. Using techniques from standard perturbation theory (SPT), previous studies of consistency relation have concentrated on continuity-momentum (Euler)-Poisson system of an ideal fluid. We investigate the consistency relations in effective field theory (EFT) which adjusts the SPT predictions to account for the departure from the ideal fluid description on small scales. We provide detailed results for the 3D density contrast δ as well as the scaled divergence of velocity θ-bar . Assuming a ΛCDM background cosmology, we find the correction to SPT results becomes important at k ∼> 0.05 h/Mpc and that the suppression from EFT to SPT results that scales as square of the wave number k , can reach 40% of the total at k ≈ 0.25 h/Mpc at z = 0. We have also investigated whether effective field theory corrections to models of primordial non-Gaussianity can alter the squeezed limit behaviour, finding the results to be rather insensitive to these counterterms. In addition, we present the EFT corrections to the squeezed limit of the bispectrum in redshift space which may be of interest for tests of theories of modified gravity.

Conflictos campesinos e indígenas en el sur de Chile (la provincia de Cautín, 1967-1973

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Jesús-Ángel Redondo Cardeñoso

2017-01-01

Full Text Available This article presents a study of the conflict between the campesinso and the indigenous (Mapuche population that took place in the province of Cautín (Chile during the cycle of social conflictivity the country experienced between 1967 and 1973. The objective is to review the traditional views that have prevailed on this topic in Chilean historiography, based on monolithic perspectives of the rural conflict. Through archival and journalistic documentation of the regional environment, it analyzes diverse manifestations of said conflict, from traditional expressions of campesino rebelliousness (cuatrerismo to modern forms of collective mobilization (agrarian trade unionism, which makes it possible to observe the diversity, complexity and heterogeneity of said conflicts and their leading actors.

Horizontal accountability and presidential dominance: a difficult combination. The case of the Dominican Republic, 1967-2009

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Leiv MARSTEINTREDET

2011-03-01

Full Text Available This article studies horizontal accountability in the Dominican Republic. First it analyses the rules regulating the system of checks and balances. Although important, institutional rules cannot explain the variation in the levels of accountability across time found in the Dominican case. Therefore, the article focuses on the execution of national budgets and the financial situation of the accountability institutions. The article suggests using an index of budgetary disproportionality based on a comparison of the congressionally approved budget and the executed budget to measure the level of horizontal accountability. A multivariate time-series regression analysis shows that budgetary disproportionality increases with presidential dominance. The article concludes that for the period 1967-2009, it is presidential behaviour more than any other factor that has prevented an effective system of checks and balances. Therefore the case confirms O’Donnell’s hypothesis of Delegative Democracies.

Política fiscal y crecimiento: nuevos resultados para las regiones españolas, 1967-1995

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Óscar Bajo Rubio

2003-01-01

Full Text Available En este trabajo se presenta una nueva evaluación de los efectos de la política fiscal sobre el crecimiento económico, desde el punto de vista del gasto público. Partiendo de un modelo teórico en el que la función de producción incorpora únicamente aquellos componentes del gasto público que deberían influir estrictamente en el proceso productivo (capital público y transferencias, se realiza una aplicación empírica para el caso de las regiones españolas durante el periodo 1967-1995. Los resultados confirman el efecto positivo sobre el crecimiento tanto del capital público como de las transferencias, siendo relativamente más intenso el del capital público en el caso de las regiones más productivas, y el de las transferencias en el de las menos productivas.

Change of occurance of type 1 and type 2 decompression sickness of divers treated at the Croatian Naval Medical Institute in the period from 1967 to 2000.

Science.gov (United States)

Andrić, Dejan; Petri, Nadan M; Stipancević, Hrvoje; Petri, Lena Vranjković; Kovacević, Hasan

2003-01-01

A significant change of occurrence (p=0.0343) of type 1 and type 2 decompression sickness (DCS) of divers in Croatia was observed in the period from 1991 to 2002 (type 1: n=26, 37.68% and type 2: n=43, 62.32%) compared with the period from 1967 to 1990 (type 1: n=93, 52.84% and type 2: n=83, 47.16%). The change was attributed to the extensive usage of diving computers and artificial gas mixtures which enable extended bottom times and deeper dives, thus putting divers at an increased decompression risk. The importance of the results of this report is in the fact that permanent neurological deficit occurs only after type 2 DCS. Injured divers with permanent loss after type 2 DCS are not fit for diving and require a long term medical care, thus becoming a significant public health problem.

Yeast Interacting Proteins Database: YFR049W, YOR047C [Yeast Interacting Proteins Database

Lifescience Database Archive (English)

Full Text Available protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator... (0) YOR047C STD1 Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sens...ors Snf3p and Rgt2p, and TATA-binding protein Spt15p; ac

Revista de Saúde Pública in scientific publications on Violence and Health (1967-2015).

Science.gov (United States)

Schraiber, Lilia Blima; Barros, Claudia; d'Oliveira, Ana Flávia Pires Lucas; Peres, Maria Fernanda Tourinho

2016-11-10

This article retrieved the publications from the Revista de Saúde Pública journal (from 1967 to 2015) on violence and health, on the SciELO and PubMed bases, by searching for the terms "violence", "suicide", "aggression", "bullying", and "external causes", registered in any part of the text. We found 130 articles (the first one published in 1974). We observed: increase of publications over time, with decrease in the last five years; similar production volume in lethal and non-lethal violence; later publication of the latter; few studies in qualitative research; mostly descriptive production; and visualization of the problem more by the acts than by contexts or motivations and aggressors. Social markers were little approached, appearing, from largest to smallest frequency, social class, gender, race/ethnicity, and generation. Human rights were little used and only recently used as analytical framework, connected more to gender than to social class. Although Revista de Saúde Pública has registered the theme in its publications, consolidating it as scientific production line, there is still great explanatory theoretical rarefaction and little intersectionality between violence, social inequalities, and human rights. RESUMO A produção da Revista de Saúde Pública (de 1967 até 2015) sobre violência e saúde foi recuperada nas bases SciELO e PubMed utilizando-se os termos "violência", "suicídio", "agressões", "bullying" e "causas externas", registrados em qualquer parte do texto. Foram encontrados 130 artigos (o primeiro deles publicado em 1974). Constatou-se: aumento das publicações no tempo, com decréscimo nos últimos cinco anos; volume similar de produção em violência letal e não letal; publicação mais tardia desta última; poucos estudos em pesquisa qualitativa; produção majoritariamente descritiva; e visibilização do problema, mais pelos atos que pelos contextos ou motivações e agressores. Os marcadores sociais foram pouco tematizados

Frozen fruit skin prick test for the diagnosis of fruit allergy.

Science.gov (United States)

Garriga, Teresa; Guilarte, Mar; Luengo, Olga; Guillén, Mercé; Labrador-Horrillo, Moisés; Fadeeva, Tatiana; Sala, Anna; Cardona, Victória

2010-12-01

Diagnosis of fruit sensitisation by skin prick test (SPT) is fast and easy to perform. Nevertheless, some fruit is not available throughout the year. Freezing aliquots of these fresh fruits to be defrosted would be a good solution to perform SPT at any time. To compare the reproducibility of SPT with Rosaceae and Cucurbitaceae frozen fruit with fresh and commercial fruit extracts. SPT with the following fruit were performed: apricot, cherry, strawberry, nectarine, Japanese medlar, peach, (peel and pulp), yellow and red plum, melon and watermelon. We compared fresh fruit, commercial extract and fruit which had been frozen at -18 degrees C. Results were read by planimetry (Inmunotek prick-film) after 15 minutes. The study group comprised 48 patients (9 males, 39 females) with a mean age of 31, 6 +/- 2.0 years. Concordance of positive and negative results was extremely high and significant in all cases. Correlation between frozen fruit and commercial extract, frozen fruit and fresh and commercial extract and fresh fruit was statistically significant in all cases except for strawberry. The use of frozen fruit is a valid method, as the performance of the SPT is similar to that of fresh fruit. This enables diagnostic procedures with seasonal fruit at any time of the year.

Geomagnetic Storm Impact On GPS Code Positioning

Science.gov (United States)

Uray, Fırat; Varlık, Abdullah; Kalaycı, İbrahim; Öǧütcü, Sermet

2017-04-01

This paper deals with the geomagnetic storm impact on GPS code processing with using GIPSY/OASIS research software. 12 IGS stations in mid-latitude were chosen to conduct the experiment. These IGS stations were classified as non-cross correlation receiver reporting P1 and P2 (NONCC-P1P2), non-cross correlation receiver reporting C1 and P2 (NONCC-C1P2) and cross-correlation (CC-C1P2) receiver. In order to keep the code processing consistency between the classified receivers, only P2 code observations from the GPS satellites were processed. Four extreme geomagnetic storms October 2003, day of the year (DOY), 29, 30 Halloween Storm, November 2003, DOY 20, November 2004, DOY 08 and four geomagnetic quiet days in 2005 (DOY 92, 98, 99, 100) were chosen for this study. 24-hour rinex data of the IGS stations were processed epoch-by-epoch basis. In this way, receiver clock and Earth Centered Earth Fixed (ECEF) Cartesian Coordinates were solved for a per-epoch basis for each day. IGS combined broadcast ephemeris file (brdc) were used to partly compensate the ionospheric effect on the P2 code observations. There is no tropospheric model was used for the processing. Jet Propulsion Laboratory Application Technology Satellites (JPL ATS) computed coordinates of the stations were taken as true coordinates. The differences of the computed ECEF coordinates and assumed true coordinates were resolved to topocentric coordinates (north, east, up). Root mean square (RMS) errors for each component were calculated for each day. The results show that two-dimensional and vertical accuracy decreases significantly during the geomagnetic storm days comparing with the geomagnetic quiet days. It is observed that vertical accuracy is much more affected than the horizontal accuracy by geomagnetic storm. Up to 50 meters error in vertical component has been observed in geomagnetic storm day. It is also observed that performance of Klobuchar ionospheric correction parameters during geomagnetic storm

War time experiences of triage and resuscitation: Australian Army nurses in the Vietnam War, 1967-1971.

Science.gov (United States)

Biedermann, N E; Harvey, N R

2001-07-01

The experiences of nurses in war is prolifically described in the North American scholarly literature, and in the Australian nursing literature to a lesser extent. The literature describes the plights and achievements of nurses caring for soldiers and civilians often under the most undesirable of circumstances. A central focus of war time nursing is the resuscitation of critically wounded soldiers. This paper addresses the experiences of the Australian Army nurses who were involved in the triage and resuscitation of critically wounded allied and enemy soldiers in the Vietnam War between 1967 and 1971. As part of a research study to explore and analyse the nature of nursing work in the Vietnam War, seventeen Vietnam veteran nurses were interviewed about their experiences. This paper explores the progression of the triage department in the Australian military hospital in Vung Tau, and it highlights that the majority of the nurses who took part in this study were clinically unprepared, particularly as emergency nurses.

Comparison of F-18-FDG PET/CT findings between pancreatic solid pseudopapillary tumor and pancreatic ductal adenocarcinoma

International Nuclear Information System (INIS)

Kim, Yong-il; Kim, Seok-ki; Paeng, Jin Chul; Lee, Ho-Young

2014-01-01

Objective: Pancreatic solid pseudopapillary tumor (SPT) is a rare benign tumor. Little data are available on positron emission tomographic/computed tomographic (PET/CT) characteristics of this tumor. Therefore, we analyzed the metabolic characteristics of SPT using F-18-FDG PET/CT and compared the results with those of pancreatic ductal adenocarcinoma. Methods: We retrospectively reviewed the records of 11 SPT patients and 46 patients with ductal adenocarcinoma. Ten SPT patients had primary tumors and 1 patient had metastatic SPT. Maximum standardized uptake value (max SUV), mean SUV, metabolic tumor volume (MTV), total lesion glycolysis (TLG), and tumor-to-background ratio (TBR) were evaluated. Mann–Whitney U test between pancreatic SPT and ductal adenocarcinoma was performed. In addition, age, gender and tumor size-adjusted analysis of covariance (ANCOVA) was done between pancreatic SPT and ductal adenocarcinoma. Results: Compared with pancreatic ductal adenocarcinomas, SPTs had significantly higher tumor size-adjusted MTV and TLG. MTV and TLG values were significantly correlated with T-stage of the SPTs. In 1 SPT patient, metastases in the liver and mesentery were revealed by intense uptake of FDG on F-18-FDG PET/CT, and after PET/CT had suggested the presence of pancreatic SPT. Conclusion: We recommend that SPT be considered when a solid pancreatic mass with increased FDG metabolism is encountered on PET/CT. F-18-FDG PET/CT may be useful in detecting subtle metastases of SPT

Causal mechanisms of seismo-EM phenomena during the 1965-1967 Matsushiro earthquake swarm

Science.gov (United States)

Enomoto, Yuji; Yamabe, Tsuneaki; Okumura, Nobuo

2017-03-01

The 1965-1967 Matsushiro earthquake swarm in central Japan exhibited two unique characteristics. The first was a hydro-mechanical crust rupture resulting from degassing, volume expansion of CO2/water, and a crack opening within the critically stressed crust under a strike-slip stress. The other was, despite the lower total seismic energy, the occurrence of complexed seismo-electromagnetic (seismo-EM) phenomena of the geomagnetic intensity increase, unusual earthquake lights (EQLs) and atmospheric electric field (AEF) variations. Although the basic rupture process of this swarm of earthquakes is reasonably understood in terms of hydro-mechanical crust rupture, the associated seismo-EM processes remain largely unexplained. Here, we describe a series of seismo-EM mechanisms involved in the hydro-mechanical rupture process, as observed by coupling the electric interaction of rock rupture with CO2 gas and the dielectric-barrier discharge of the modelled fields in laboratory experiments. We found that CO2 gases passing through the newly created fracture surface of the rock were electrified to generate pressure-impressed current/electric dipoles, which could induce a magnetic field following Biot-Savart’s law, decrease the atmospheric electric field and generate dielectric-barrier discharge lightning affected by the coupling effect between the seismic and meteorological activities.

An Investigation of the Ionospheric Disturbances Due to the 2014 Sudden Stratospheric Warming Events Over Brazilian Sector

Science.gov (United States)

de Jesus, R.; Batista, I. S.; Jonah, O. F.; de Abreu, A. J.; Fagundes, P. R.; Venkatesh, K.; Denardini, C. M.

2017-11-01

The present study investigates the ionospheric F region response in the Brazilian sector due to sudden stratospheric warming (SSW) events of 2014. The data used for this work are obtained from GPS receivers and magnetometer measurements during day of year (DOY) 01 to 120, 2014 at different stations in the equatorial and low-latitude regions in the Brazilian sector. In addition, the data obtained from Communication/Navigation Outage Forecasting System satellites during DOY 01 to 75 of 2014 are used. The main novelty of this research is that, during the 2014 SSW events, daytime vertical total electron content (VTEC) shows a strong increase on the order of about 23% and 11% over the equatorial and low-latitude regions, respectively. We also observed that the nighttime VTEC (SSW days) is increased by 8% and 33% over equatorial and low-latitude regions, respectively. The magnetometer measurements show a strong counterelectrojet during the SSW days. The results show an amplification of the 0.5 day and 2-16 day periods in the VTEC and equatorial electrojet during the SSWs. The occurrences of ionospheric irregularities during the SSW events are around 84% and 53% in the equatorial and low-latitude regions, respectively, which is less frequent when compared with those during the pre-SSW periods.

Novel Two-Component System of Streptococcus sanguinis Affecting Functions Associated with Viability in Saliva and Biofilm Formation.

Science.gov (United States)

Camargo, Tarsila M; Stipp, Rafael N; Alves, Lívia A; Harth-Chu, Erika N; Höfling, José F; Mattos-Graner, Renata O

2018-04-01

Streptococcus sanguinis is a pioneer species of teeth and a common opportunistic pathogen of infective endocarditis. In this study, we identified a two-component system, S. sanguinis SptRS (SptRS Ss ), affecting S. sanguinis survival in saliva and biofilm formation. Isogenic mutants of sptR Ss (SKsptR) and sptS Ss (SKsptS) showed reduced cell counts in ex vivo assays of viability in saliva compared to those of parent strain SK36 and complemented mutants. Reduced counts of the mutants in saliva were associated with reduced growth rates in nutrient-poor medium (RPMI) and increased susceptibility to the deposition of C3b and the membrane attach complex (MAC) of the complement system, a defense component of saliva and serum. Conversely, sptR Ss and sptS Ss mutants showed increased biofilm formation associated with higher levels of production of H 2 O 2 and extracellular DNA. Reverse transcription-quantitative PCR (RT-qPCR) comparisons of strains indicated a global role of SptRS Ss in repressing genes for H 2 O 2 production (2.5- to 15-fold upregulation of spxB , spxR , vicR , tpk , and ackA in sptR Ss and sptS Ss mutants), biofilm formation, and/or evasion of host immunity (2.1- to 11.4-fold upregulation of srtA , pcsB , cwdP , iga , and nt5e ). Compatible with the homology of SptR Ss with AraC-type regulators, duplicate to multiple conserved repeats were identified in 1,000-bp regulatory regions of downstream genes, suggesting that SptR Ss regulates transcription by DNA looping. Significant transcriptional changes in the regulatory genes vicR , spxR , comE , comX , and mecA in the sptR Ss and sptS Ss mutants further indicated that SptRS Ss is part of a regulatory network that coordinates cell wall homeostasis, H 2 O 2 production, and competence. This study reveals that SptRS Ss is involved in the regulation of crucial functions for S. sanguinis persistence in the oral cavity. Copyright © 2018 American Society for Microbiology.

Revista de Saúde Pública in scientific publications on Violence and Health (1967-2015

Directory of Open Access Journals (Sweden)

Lilia Blima Schraiber

Full Text Available ABSTRACT This article retrieved the publications from the Revista de Saúde Pública journal (from 1967 to 2015 on violence and health, on the SciELO and PubMed bases, by searching for the terms “violence”, “suicide”, “aggression”, “bullying”, and “external causes”, registered in any part of the text. We found 130 articles (the first one published in 1974. We observed: increase of publications over time, with decrease in the last five years; similar production volume in lethal and non-lethal violence; later publication of the latter; few studies in qualitative research; mostly descriptive production; and visualization of the problem more by the acts than by contexts or motivations and aggressors. Social markers were little approached, appearing, from largest to smallest frequency, social class, gender, race/ethnicity, and generation. Human rights were little used and only recently used as analytical framework, connected more to gender than to social class. Although Revista de Saúde Pública has registered the theme in its publications, consolidating it as scientific production line, there is still great explanatory theoretical rarefaction and little intersectionality between violence, social inequalities, and human rights.

Pollen food allergy syndrome in Turkey: Clinical characteristics and evaluation of its association with skin test reactivity to pollens.

Science.gov (United States)

Özdemir, Seςil Kepil; Özgüςlü, Selcan

2017-09-17

There is limited data regarding pollen food allergy syndrome (PFAS) in Turkey. To investigate the clinical characteristics and possible risk factors of PFAS in Turkey, and to evaluate if there was an association between skin test reactivity to pollens and presence of PFAS. A total of 254 consecutive adult patients with pollen sensitivity were prospectively recruited. Patients were interviewed with a questionnaire including a list of pollen-associated foods. Patients were classified as having PFAS if they reported clear allergic symptoms compatible with PFAS. All participants underwent skin prick tests (SPT) to a panel of common aeroallergens, prick-to-prick tests with culprit fresh foods were performed in patients who gave consent. Self-reported PFAS was observed in 49 patients (19.3%). The most common culprit foods were kiwi, peach, tomato, melon and watermelon. Multiple logistic regression analysis showed that potential risk factors for PFAS were having asthma (OR=2.392, P=0.044) and tree pollen sensitization (OR=2.904, P=0.004). There were no significant differences in the SPT wheal sizes to individual pollen extracts between patients with and without PFAS with a positive SPT result for that pollen extract (P> 0.05). PFAS is frequent in pollen sensitized adults in Turkey. The most commonly implicated foods are kiwi, peach,tomato, melon and watermelon, in our geographical region. SPT wheal sizes to pollen extracts seems to be similar in patients with and without PFAS.

AASM standards of practice compliant validation of actigraphic sleep analysis from SOMNOwatch(TM) versus polysomnographic sleep diagnostics shows high conformity also among subjects with sleep disordered breathing

International Nuclear Information System (INIS)

Dick, R; Schulz, J; Penzel, T; Fietze, I; Partinen, M; Hein, H

2010-01-01

In recent AASM practice, parameter actimetry is cited to measure total sleep time in obstructive sleep apnoea patients, when polysomnography is not available. An actigraph was therefore compared to polysomnographic data in 28 subjects with known sleep disordered breathing. Total sleep time (TST), sleep period time (SPT), sleep efficiency (SE), sustained sleep efficiency (SSE), sleep onset latency (SL) and sleep/wake pattern were compared to gold standard polysomnography. The results of an epoch-by-epoch comparison of sleep/wake from actigraphy to sleep stages from polysomnography gave a sensitivity of 90.2%, a specificity of 95.2% and an overall accuracy of 85.9%. Correlations were moderately strong for SE (0.71, p < 0.001) and SSE (0.65, p < 0.001) and high for TST (0.89, p < 0.001), SPT (0.91, p < 0.001) and SL (0.89, p < 0.001). It was concluded that actigraphy is not identical with PSG recording but gives good results in sleep/wake patterns and predicting TST, SPT, SSE, SE and SL also in sleep apnoea patients not suffering from other sleep disorders. The difficult detection of correct sleep onset causes SSE and SL to be less predictable. Therefore a 15-epoch criterion was introduced and resulted in high correlation of 0.89 for sleep latency, but has to be tested on a bigger population

A study of the asymmetrical distribution of solar activity features on solar and plasma parameters (1967-2016)

Science.gov (United States)

El-Borie, M. A.; El-Taher, A. M.; Aly, N. E.; Bishara, A. A.

2018-04-01

The impact of asymmetrical distribution of hemispheric sunspot areas (SSAs) on the interplanetary magnetic field, plasma, and solar parameters from 1967 to 2016 has been studied. The N-S asymmetry of solar-plasma activities based on SSAs has a northern dominance during solar cycles 20 and 24. However, it has a tendency to shift to the southern hemisphere in cycles 21, 22, and 23. The solar cycle 23 showed that the sorted southern SSAs days predominated over the northern days by ˜17%. Through the solar cycles 21-24, the SSAs of the southern hemisphere were more active. In contrast, the northern SSAs predominate over the southern one by 9% throughout solar cycle 20. On the other hand, the average differences of field magnitude for the sorted northern and southern groups during solar cycles 20-24 are statistically insignificant. Clearly, twenty years showed that the solar plasma ion density from the sorted northern group was denser than that of southern group and a highest northern dominant peak occurred in 1971. In contrast, seventeen out of fifty years showed the reverse. In addition, there are fifteen clear asymmetries of solar wind speed (SWS), with SWS (N) > SWS (S), and during the years 1972, 2002, and 2008, the SWS from the sorted northern group was faster than that of southern activity group by 6.16 ± 0.65 km/s, 5.70 ± 0.86 km/s, and 5.76 ± 1.35 km/s, respectively. For the solar cycles 20-24, the grand-averages of P from the sorted solar northern and southern have nearly the same parameter values. The solar plasma was hotter for the sorted northern activity group than the southern ones for 17 years out of 50. Most significant northern prevalent asymmetries were found in 1972 (5.76 ± 0.66 × 103 K) and 1996 (4.7 ± 0.8 × 103 K), while two significant equivalent dominant southern asymmetries (˜3.8 ± 0.3 × 103 K) occurred in 1978 and 1993. The grand averages of sunspot numbers have symmetric activity for the two sorted northern and southern hemispheres

Galaxy Kinematics and Mass Calibration in Massive SZE Selected Galaxy Clusters to z=1.3

Energy Technology Data Exchange (ETDEWEB)

Capasso, R.; et al.

2017-11-27

The galaxy phase-space distribution in galaxy clusters provides insights into the formation and evolution of cluster galaxies, and it can also be used to measure cluster mass profiles. We present a dynamical study based on $\\sim$3000 passive, non-emission line cluster galaxies drawn from 110 galaxy clusters. The galaxy clusters were selected using the Sunyaev-Zel'dovich effect (SZE) in the 2500 deg$^2$ SPT-SZ survey and cover the redshift range $0.2 < z < 1.3$. We model the clusters using the Jeans equation, while adopting NFW mass profiles and a broad range of velocity dispersion anisotropy profiles. The data prefer velocity dispersion anisotropy profiles that are approximately isotropic near the center and increasingly radial toward the cluster virial radius, and this is true for all redshifts and masses we study. The pseudo-phase-space density profile of the passive galaxies is consistent with expectations for dark matter particles and subhalos from cosmological $N$-body simulations. The dynamical mass constraints are in good agreement with external mass estimates of the SPT cluster sample from either weak lensing, velocity dispersions, or X-ray $Y_X$ measurements. However, the dynamical masses are lower (at the 2.2$\\sigma$ level) when compared to the mass calibration favored when fitting the SPT cluster data to a LCDM model with external cosmological priors, including CMB anisotropy data from Planck. The tension grows with redshift, where in the highest redshift bin the ratio of dynamical to SPT+Planck masses is $\\eta=0.63^{+0.13}_{-0.08}\\pm0.05$ (statistical and systematic), corresponding to 2.6$\\sigma$ tension.

Interpretation of the U.S.A. oceanographer sounding and radon data over the Arabian Sea during June 1967

International Nuclear Information System (INIS)

Rao, Y.P.; Desai, B.N.

1974-01-01

U.S.A. 'Oceanographer' sounding and radon data during June 1967 have been discussed with reference to the synoptic charts. During the period 14 to 21 June, there was above the surface layer of maritime air, less moist air with nearly saturation adiabatic lapse from the south Arabian Sea instead of the dry continental air from northeast Africa and Arabia. The 'Oceanographer' soundings compare well with those at Bombay, if one keeps in mind the effect of the Ghats for the latter location. The radon data show that there was presence of the maritime air from across the equator, which had got mixed to some extent with continental air from northeast Africa and Arabia; the high radon values off Saurashtra-Konkan were not due to vertical mixing of the lower maritime air with the upper continental air (author)

Interpretation of the U.S.A. oceanographer sounding and radon data over the Arabian Sea during June 1967

International Nuclear Information System (INIS)

Rao, Y.P.; Desai, B.N.

1974-01-01

U.S.A. 'Oceanographer' sounding and radon data during June 1967 have been discussed with reference to the synoptic charts. During the period 14 to 21 June, there was above the surface layer of maritime air, less moist air with nearly saturation adiabatic lapse from the south Arabian Sea instead of the dry continental air from northeast Africa and Arabia. The 'Oceanographer' soundings compare well with those at Bombay, if one keeps in mind the effect of the Ghats for the latter location. The radon data show that there was presence of the maritime air from across the equator, which had got mixed to some extent with continental air from northeast Africa and Arabia; the high radon values off Saurashtra-Konkan were not due to vertical mixing of the lower maritime air with the upper continental air. (author)

Sound production treatment for acquired apraxia of speech: Effects of blocked and random practice on multisyllabic word production.

Science.gov (United States)

Wambaugh, Julie; Nessler, Christina; Wright, Sandra; Mauszycki, Shannon; DeLong, Catharine

2016-10-01

This study was designed to examine the effects of practice schedule, blocked vs random, on outcomes of a behavioural treatment for acquired apraxia of speech (AOS), Sound Production Treatment (SPT). SPT was administered to four speakers with chronic AOS and aphasia in the context of multiple baseline designs across behaviours and participants. Treatment was applied to multiple sound errors within three-to-five syllable words. All participants received both practice schedules: SPT-Random (SPT-R) and SPT-Blocked (SPT-B). Improvements in accuracy of word production for trained items were found for both treatment conditions for all participants. One participant demonstrated better maintenance effects associated with SPT-R. Response generalisation to untreated words varied across participants, but was generally modest and unstable. Stimulus generalisation to production of words in sentence completion was positive for three of the participants. Stimulus generalisation to production of phrases was positive for two of the participants. Findings provide additional efficacy data regarding SPT's effects on articulation of treated items and extend knowledge of the treatment's effects when applied to multiple targets within multisyllabic words.

OBSERVATIONS OF THE HELIOSHEATH AND SOLAR WIND NEAR THE TERMINATION SHOCK BY VOYAGER 2

International Nuclear Information System (INIS)

Burlaga, L. F.; Ness, N. F.; Acuna, M. H.; Richardson, J. D.; Stone, E.; McDonald, F. B.

2009-01-01

This paper describes the principal features of 24 hr averages of the magnetic field strength variations B(t) and their relationships to the plasma and energetic particles observed prior to and after the crossing of the termination shock (TS) by Voyager 2 (V2). The solar wind (pre-TS crossing) and heliosheath (post-TS crossing) data extend from day of year (DOY) 1 through 241, 2007 and from 2007 DOY 245 through 2008 DOY 80, respectively. In the solar wind, two merged interaction regions (MIRs) were observed in which the ratio of plasma pressure to magnetic pressure in the solar wind was relatively low. Strong magnetic fields and low values of beta were also observed just prior to its crossing of the TS. The predicted correlation between peaks in the intensity of energetic particles in the solar wind when V2 crossed the heliospheric current sheet from positive to negative magnetic polarity in the solar wind was not observed. In the heliosheath, V2 observed a feature characterized by large enhancements of the density N and the proton temperature T, a small increase in speed V, and a depression in B. The distributions of 24 hr averages of B and beta were approximately log-normal in both the solar wind and the heliosheath. A unipolar region was observed for 73 days in the heliosheath, as the heliospheric current sheet moved toward the equatorial plane to latitudes lower than V2.

Horizontal accountability and presidential dominance: a difficult combination. The case of the Dominican Republic, 1967-2009 Rendición de cuentas horizontal y preponderancia presidencial: una combinación difícil. El caso de República Dominicana, 1967-2009

Directory of Open Access Journals (Sweden)

Leiv MARSTEINTREDET

2011-03-01

Full Text Available This article studies horizontal accountability in the Dominican Republic. First it analyses the rules regulating the system of checks and balances. Although important, institutional rules cannot explain the variation in the levels of accountability across time found in the Dominican case. Therefore, the article focuses on the execution of national budgets and the financial situation of the accountability institutions. The article suggests using an index of budgetary disproportionality based on a comparison of the congressionally approved budget and the executed budget to measure the level of horizontal accountability. A multivariate time-series regression analysis shows that budgetary disproportionality increases with presidential dominance. The article concludes that for the period 1967-2009, it is presidential behaviour more than any other factor that has prevented an effective system of checks and balances. Therefore the case confirms O’Donnell’s hypothesis of Delegative Democracies.Este artículo estudia la rendición de cuentas horizontal en República Dominicana. Primero se estudian las normas constitucionales que regulan el sistema de pesos y contrapesos. Aunque importantes, estas no explican la gran variación en niveles de rendición de cuentas observada en el caso dominicano. Por lo tanto, el trabajo se enfoca en el ejercicio de los gastos de los presupuestos nacionales y la situación financiera de las instituciones de control. El artículo sugiere analizar la situación presupuestaria de las instituciones fiscalizadoras y propone utilizar la desproporcionalidad entre el presupuesto aprobado y el ejecutado como un indicador del nivel de rendición de cuentas en un país. Un análisis multivariado de regresión de series de tiempo demuestra que la desproporcionalidad presupuestal aumenta con la preponderancia presidencial. Se concluye que, para el caso dominicano en el período 1967-2009, el comportamiento de varios presidentes m

Clinical relevance is associated with allergen-specific wheal size in skin prick testing

DEFF Research Database (Denmark)

Haahtela, T.; Burbach, G. J.; Bachert, C.

2014-01-01

, asthma, atopic dermatitis, food allergy). The effects of age, gender, and geographical area on SPT results were assessed. For each allergen, the wheal size in mm with an 80% positive predictive value (PPV) for being clinically relevant was calculated. ResultsDepending on the allergen, from 40% (blatella...... by providing quantitative decision points. MethodsThe GA(2)LEN SPT study with 3068 valid data sets was used to investigate the relationship between SPT results and patient-reported clinical relevance for each of the 18 inhalant allergens as well as SPT wheal size and physician-diagnosed allergy (rhinitis...... SPT reactions had a smaller risk of sensitizations being clinically relevant compared with adults. The 80% PPV varied from 3 to 10mm depending on the allergen. ConclusionThese reading keys' for 18 inhalant allergens can help interpret SPT results with respect to their clinical significance. A SPT form...

Homosexual Liberation Movements in Latin America. Historiographical Contributions from a Comparative Perspective between Argentina, Brazil, Chile, Colombia and Mexico (1967-1982

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Patricio Simonetto

2017-07-01

Full Text Available Between 1967 and 1982, homosexual liberation movements emerged in Latin America that sought to unify strategies of social and sexual revolution. This article proposes a comparative study to rethink the periodization of the distinct selection of cases and analyze the similarities and differences between them. For this, the cases of Argentina, Brazil, Chile, Colombia and Mexico are discussed. The purpose of this paper is to find a different explanation for these movements that avoids viewing them as just a projection of the Stonewall uprising (1969, thereby bringing forward an explanatory variable from within Latin America. In turn, the respective relationships of these movements with the local radical Left and the State are also considered.

A 2500 deg ² CMB Lensing Map from Combined South Pole Telescope and Planck Data

Energy Technology Data Exchange (ETDEWEB)

Omori, Y.; Chown, R.; Simard, G.; Story, K. T.; Aylor, K.; Baxter, E. J.; Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Cho, H-M.; Crawford, T. M.; Crites, A. T.; Haan, T. de; Dobbs, M. A.; Everett, W. B.; George, E. M.; Halverson, N. W.; Harrington, N. L.; Holder, G. P.; Hou, Z.; Holzapfel, W. L.; Hrubes, J. D.; Knox, L.; Lee, A. T.; Leitch, E. M.; Luong-Van, D.; Manzotti, A.; Marrone, D. P.; McMahon, J. J.; Meyer, S. S.; Mocanu, L. M.; Mohr, J. J.; Natoli, T.; Padin, S.; Pryke, C.; Reichardt, C. L.; Ruhl, J. E.; Sayre, J. T.; Schaffer, K. K.; Shirokoff, E.; Staniszewski, Z.; Stark, A. A.; Vanderlinde, K.; Vieira, J. D.; Williamson, R.; Zahn, O.

2017-11-07

We present a cosmic microwave background (CMB) lensing map produced from a linear combination of South Pole Telescope (SPT) and \\emph{Planck} temperature data. The 150 GHz temperature data from the $2500\\ {\\rm deg}^{2}$ SPT-SZ survey is combined with the \\emph{Planck} 143 GHz data in harmonic space, to obtain a temperature map that has a broader $\\ell$ coverage and less noise than either individual map. Using a quadratic estimator technique on this combined temperature map, we produce a map of the gravitational lensing potential projected along the line of sight. We measure the auto-spectrum of the lensing potential $C_{L}^{\\phi\\phi}$, and compare it to the theoretical prediction for a $\\Lambda$CDM cosmology consistent with the \\emph{Planck} 2015 data set, finding a best-fit amplitude of $0.95_{-0.06}^{+0.06}({\\rm Stat.})\\! _{-0.01}^{+0.01}({\\rm Sys.})$. The null hypothesis of no lensing is rejected at a significance of $24\\,\\sigma$. One important use of such a lensing potential map is in cross-correlations with other dark matter tracers. We demonstrate this cross-correlation in practice by calculating the cross-spectrum, $C_{L}^{\\phi G}$, between the SPT+\\emph{Planck} lensing map and Wide-field Infrared Survey Explorer (\\emph{WISE}) galaxies. We fit $C_{L}^{\\phi G}$ to a power law of the form $p_{L}=a(L/L_{0})^{-b}$ with $a=2.15 \\times 10^{-8}$, $b=1.35$, $L_{0}=490$, and find $\\eta^{\\phi G}=0.94^{+0.04}_{-0.04}$, which is marginally lower, but in good agreement with $\\eta^{\\phi G}=1.00^{+0.02}_{-0.01}$, the best-fit amplitude for the cross-correlation of \\emph{Planck}-2015 CMB lensing and \\emph{WISE} galaxies over $\\sim67\\%$ of the sky. The lensing potential map presented here will be used for cross-correlation studies with the Dark Energy Survey (DES), whose footprint nearly completely covers the SPT $2500\\ {\\rm deg}^2$ field.

A 2500 deg2 CMB Lensing Map from Combined South Pole Telescope and Planck Data

International Nuclear Information System (INIS)

Omori, Y.; Chown, R.; Simard, G.; Story, K. T.; University of Chicago, IL

2017-01-01

Here, we present a cosmic microwave background (CMB) lensing map produced from a linear combination of South Pole Telescope (SPT) and Planck temperature data. The 150 GHz temperature data from the 2500 deg 2 SPT-SZ survey is combined with the Planck 143 GHz data in harmonic space to obtain a temperature map that has a broader ℓ coverage and less noise than either individual map. Using a quadratic estimator technique on this combined temperature map, we produce a map of the gravitational lensing potential projected along the line of sight. We measure the auto-spectrum of the lensing potential C L ϕϕ , and compare it to the theoretical prediction for a ΛCDM cosmology consistent with the Planck 2015 data set, finding a best-fit amplitude of 0.95 −0.06 +0.06 (stat.) −0.01 +0.01 (sys.). The null hypothesis of no lensing is rejected at a significance of 24σ. One important use of such a lensing potential map is in cross-correlations with other dark matter tracers. We demonstrate this cross-correlation in practice by calculating the cross-spectrum, C L ϕG , between the SPT+Planck lensing map and Wide-field Infrared Survey Explorer (WISE) galaxies. We fit C L ϕG to a power law of the form p L =a(L/L 0 ) −b with a, L 0, and b fixed, and find η ϕG =C L ϕG /p L =0.94 −0.04 +0.04 , which is marginally lower, but in good agreement with η ϕG =1.00 −0.01 +0.02 , the best-fit amplitude for the cross-correlation of Planck-2015 CMB lensing and WISE galaxies over ~67% of the sky. Finally, the lensing potential map presented here will be used for cross-correlation studies with the Dark Energy Survey, whose footprint nearly completely covers the SPT 2500 deg 2 field.

Las capas medios asalariadas y la evolución de los comportamientos electorales en Francia, 1967-1984

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GERARD GRUNBERG

1984-01-01

Full Text Available Las clases medias trabajadores jugaron un papel decisivo en la reconstrucción de la base del Partido Socialista Francés entre los años 1967 y 1981. Sin embargo, sus triunfos electorales fueron seguidos de un debilitamiento de su base de poder desde 1981 hasta 1984. El mandato socialista inicial de Mitterrand en 1981 condujo a una sobrestimación de las aspiraciones de reorganización social. Los datos procedentes de encuestas de ámbito nacional en 1983 mostraban que el principal objetivo de la mayoría de ciudadanos era una mejora de las condiciones de vida cotidianas. El sistema que pueda conseguir este objetivo será el mejor. La mayoría de los trabajadores de las clases medias son conscientes de la importancia de los temas que afectan a los derechos humanos en democracia; sin embargo, no apoyan una redistribución radical de la pobreza.

Opisthorchis felineus negatively associates with skin test reactivity in Russia-EuroPrevall-International Cooperation study.

Science.gov (United States)

Fedorova, O S; Janse, J J; Ogorodova, L M; Fedotova, M M; Achterberg, R A; Verweij, J J; Fernández-Rivas, M; Versteeg, S A; Potts, J; Minelli, C; van Ree, R; Burney, P; Yazdanbakhsh, M

2017-07-01

Most studies on the relationship between helminth infections and atopic disorders have been conducted in (sub)tropical developing countries where exposure to multiple parasites and lifestyle can confound the relationship. We aimed to study the relationship between infection with the fish-borne helminth Opishorchis felineus and specific IgE, skin prick testing, and atopic symptoms in Western Siberia, with lifestyle and hygiene standards of a developed country. Schoolchildren aged 7-11 years were sampled from one urban and two rural regions. Skin prick tests (SPT) and specific IgE (sIgE) against food and aeroallergens were measured, and data on allergic symptoms and on demographic and socioeconomic factors were collected by questionnaire. Diagnosis of opisthorchiasis was based on PCR performed on stool samples. Of the 732 children included, 34.9% had opisthorchiasis. The sensitization to any allergen when estimated by positive SPT was 12.8%, while much higher, 24.0%, when measured by sIgE. Atopic symptoms in the past year (flexural eczema and/or rhinoconjunctivitis) were reported in 12.4% of the children. SPT was positively related to flexural eczema and rhinoconjunctivitis, but not to wheezing. Opisthorchiasis showed association with lower SPT response, as well as borderline association with low IgE reactivity to any allergen. However, the effect of opisthorchiasis on SPT response was not mediated by IgE, suggesting that opisthorchiasis influences SPT response through another mechanism. Opisthorchiasis also showed borderline association with lower atopic symptoms. There is a negative association between a chronic helminth infection and skin prick test reactivity even in a developed country. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Comparing cycling world hour records, 1967-1996: modeling with empirical data.

Science.gov (United States)

Bassett, D R; Kyle, C R; Passfield, L; Broker, J P; Burke, E R

1999-11-01

The world hour record in cycling has increased dramatically in recent years. The present study was designed to compare the performances of former/current record holders, after adjusting for differences in aerodynamic equipment and altitude. Additionally, we sought to determine the ideal elevation for future hour record attempts. The first step was constructing a mathematical model to predict power requirements of track cycling. The model was based on empirical data from wind-tunnel tests, the relationship of body size to frontal surface area, and field power measurements using a crank dynamometer (SRM). The model agreed reasonably well with actual measurements of power output on elite cyclists. Subsequently, the effects of altitude on maximal aerobic power were estimated from published research studies of elite athletes. This information was combined with the power requirement equation to predict what each cyclist's power output would have been at sea level. This allowed us to estimate the distance that each rider could have covered using state-of-the-art equipment at sea level. According to these calculations, when racing under equivalent conditions, Rominger would be first, Boardman second, Merckx third, and Indurain fourth. In addition, about 60% of the increase in hour record distances since Bracke's record (1967) have come from advances in technology and 40% from physiological improvements. To break the current world hour record, field measurements and the model indicate that a cyclist would have to deliver over 440 W for 1 h at sea level, or correspondingly less at altitude. The optimal elevation for future hour record attempts is predicted to be about 2500 m for acclimatized riders and 2000 m for unacclimatized riders.

Long-term repeatability of the skin prick test is high when supported by history or allergen-sensitivity tests

DEFF Research Database (Denmark)

Bødtger, Uffe; Jacobsen, C R; Poulsen, L K

2003-01-01

subjects. An SPT was positive when > or =3 mm, and repeatable if either persistently positive or negative. Clinical sensitivity to birch pollen was used as model for inhalation allergy, and was investigated at inclusion and at study termination by challenge tests, intradermal test, titrated SPT and Ig......E measurements. Birch pollen symptoms were confirmed in diaries. RESULTS: The repeatability of a positive SPT was 67%, increasing significantly to 100% when supported by the history. When not supported by history, the presence of specific IgE was significantly associated with a repeatable SPT. Allergen....... CONCLUSION: SPT changes are clinically relevant. Further studies using other allergens are needed. Long-term repeatability of SPT is high in the presence of a supportive history....

Gravitational spreading, bookshelf faulting, and tectonic evolution of the South Polar Terrain of Saturn's moon Enceladus

Science.gov (United States)

Yin, An; Pappalardo, Robert T.

2015-11-01

Despite a decade of intense research the mechanical origin of the tiger-stripe fractures (TSF) and their geologic relationship to the hosting South Polar Terrain (SPT) of Enceladus remain poorly understood. Here we show via systematic photo-geological mapping that the semi-squared SPT is bounded by right-slip, left-slip, extensional, and contractional zones on its four edges. Discrete deformation along the edges in turn accommodates translation of the SPT as a single sheet with its transport direction parallel to the regional topographic gradient. This parallel relationship implies that the gradient of gravitational potential energy drove the SPT motion. In map view, internal deformation of the SPT is expressed by distributed right-slip shear parallel to the SPT transport direction. The broad right-slip shear across the whole SPT was facilitated by left-slip bookshelf faulting along the parallel TSF. We suggest that the flow-like tectonics, to the first approximation across the SPT on Enceladus, is best explained by the occurrence of a transient thermal event, which allowed the release of gravitational potential energy via lateral viscous flow within the thermally weakened ice shell.

FACT, the Bur kinase pathway, and the histone co-repressor HirC have overlapping nucleosome-related roles in yeast transcription elongation.

Directory of Open Access Journals (Sweden)

Jennifer R Stevens

Full Text Available Gene transcription is constrained by the nucleosomal nature of chromosomal DNA. This nucleosomal barrier is modulated by FACT, a conserved histone-binding heterodimer. FACT mediates transcription-linked nucleosome disassembly and also nucleosome reassembly in the wake of the RNA polymerase II transcription complex, and in this way maintains the repression of 'cryptic' promoters found within some genes. Here we focus on a novel mutant version of the yeast FACT subunit Spt16 that supplies essential Spt16 activities but impairs transcription-linked nucleosome reassembly in dominant fashion. This Spt16 mutant protein also has genetic effects that are recessive, which we used to show that certain Spt16 activities collaborate with histone acetylation and the activities of a Bur-kinase/Spt4-Spt5/Paf1C pathway that facilitate transcription elongation. These collaborating activities were opposed by the actions of Rpd3S, a histone deacetylase that restores a repressive chromatin environment in a transcription-linked manner. Spt16 activity paralleling that of HirC, a co-repressor of histone gene expression, was also found to be opposed by Rpd3S. Our findings suggest that Spt16, the Bur/Spt4-Spt5/Paf1C pathway, and normal histone abundance and/or stoichiometry, in mutually cooperative fashion, facilitate nucleosome disassembly during transcription elongation. The recessive nature of these effects of the mutant Spt16 protein on transcription-linked nucleosome disassembly, contrasted to its dominant negative effect on transcription-linked nucleosome reassembly, indicate that mutant FACT harbouring the mutant Spt16 protein competes poorly with normal FACT at the stage of transcription-linked nucleosome disassembly, but effectively with normal FACT for transcription-linked nucleosome reassembly. This functional difference is consistent with the idea that FACT association with the transcription elongation complex depends on nucleosome disassembly, and that the

Subsidence of the South Polar Terrain and global tectonic of Enceladus

Science.gov (United States)

Czechowski, Leszek

2016-04-01

Introduction: Enceladus is the smallest celestial body in the Solar System where volcanic and tectonic activities are observed. Every second, the mass of ˜200 kg is ejected into space from the South Polar Terrain (SPT) - [1]. The loss of matter from the body's interior should lead to global compression of the crust (like on Mercury). Typical effects of compression are: thrust faults, folding and subduction. However, such forms are not dominant on Enceladus. We propose here special dynamical process that could explain this paradox. Our hypothesis states that the mass loss from SPT is the main driving mechanism of the following tectonic processes: subsidence of SPT, flow in the mantle and motion of adjacent tectonic plates. The hypothesis is presented in [2] and [3]. We suggest that the loss of the volatiles results in a void, an instability, and motion of solid matter to fill the void. The motion includes: Subsidence of the 'lithosphere' of SPT. Flow of the matter in the mantle. Motion of plates adjacent to SPT towards the active region. Methods and results: The numerical model of the subsidence process is developed. It is based on the model of thermal convection in the mantle. Special boundary conditions are applied, that could simulate subsidence of SPT. If emerging void is being filled by the subsidence of SPT only, then the velocity of subsidence is ˜0.05 mmṡyr-1. However, numerical calculations indicate that all three types of motion are usually important. The role of a given motion depends on the viscosity distribution. Generally, for most of the models the subsidence is ˜0.02 mmṡyr-1, but mantle flow and plates' motion also play a role in filling the void. The preliminary results of the numerical model indicate also that the velocity of adjacent plates could be ˜0.02 mmṡyr-1 for the Newtonian rheology. Note that in our model the reduction of the crust area is not a result of compression but it is a result of the plate sinking. Therefore the

The probe rules in single particle tracking

DEFF Research Database (Denmark)

Clausen, Mathias P.; Lagerholm, B. Christoffer

2011-01-01

techniques and probes that have made historically very demanding and specialized bio-imaging techniques more easily accessible and achievable. SPT has in particular found extensive use for analyzing the molecular organization of biological membranes. From these and other studies using complementary...... techniques it has been determined that the organization of native plasma membranes is heterogeneous over a very large range of spatial and temporal scales. The observed heterogeneities in the organization have the practical consequence that the SPT results in investigations of native plasma membranes...... are time dependent. Furthermore, because the accessible time dynamics, and also the spatial resolution, in an SPT experiment is mainly dependent on the luminous brightness and photostability of the particular SPT probe that is used, available SPT results are ultimately dependent on the SPT probes...

CLINICAL APPLICATIONS OF CRYOTHERAPY AMONG SPORTS PHYSICAL THERAPISTS.

Science.gov (United States)

Hawkins, Shawn W; Hawkins, Jeremy R

2016-02-01

Therapeutic modalities (TM) are used by sports physical therapists (SPT) but how they are used is unknown. To identify the current clinical use patterns for cryotherapy among SPT. Cross-sectional survey. All members (7283) of the Sports Physical Therapy Section of the APTA were recruited. A scenario-based survey using pre-participation management of an acute or sub-acute ankle sprain was developed. A Select Survey link was distributed via email to participants. Respondents selected a treatment approach based upon options provided. Follow-up questions were asked. The survey was available for two weeks with a follow-up email sent after one week. Question answers were the main outcome measures. Reliability: Cronbach's alpha=>0.9. The SPT response rate = 6.9% (503); responses came from 48 states. Survey results indicated great variability in respondents' approaches to the treatment of an acute and sub-acute ankle sprain. SPT applied cryotherapy with great variability and not always in accordance to the limited research on the TM. Continuing education, application of current research, and additional outcomes based research needs to remain a focus for clinicians. 3.

Slip safety risk analysis of surface properties using the coefficients of friction of rocks.

Science.gov (United States)

Çoşkun, Gültekin; Sarıışık, Gencay; Sarıışık, Ali

2017-12-19

This study was conducted to determine the most appropriate surface processing techniques (SPT), environmental conditions (EC) and surface roughness (SR) to minimize the risk of slipping when pedestrians walk on a floor covering of rocks barefoot and with shoes. Coefficients of friction (COFs) and values of SR were found using five different types of rocks, four SPT and two (ramp and pendulum) tests. Results indicate that the parameters which affect the COF values of rocks include SR, EC and SPT. Simple linear regression was performed to examine the relationship between the values of the COF and the SR. The value of the COF was identified as R 2  ≥ 0.864. Statistical results, which are based on experimental measurements, show that rocks are classified according to their safe use areas depending on their COF and SR values.

A controversy on moral judgment: Fifteen historian-reviewers in the controversy on Hannah Arendt’s book Eichmann in Jerusalem in the US, West Germany and France, 1963-1967. A historical and a pragma-dialectical perspective

NARCIS (Netherlands)

Boers, M.

2016-01-01

This dissertation consists of two parts. The first part is the result of thorough historical research into the development and content of the discussion of Hannah Arendt’s book ‘Eichmann in Jerusalem’ between 1963 and 1967, in three countries: the US, West Germany and France. This part corrects and

Lessons denied: a history of therapeutic response to combat stress reaction during Israel's War of Independence (1948), the Sinai Campaign (1956) and the Six Day War (1967)

Science.gov (United States)

Witztum, E; Levy, A; Solomon, Z

1996-01-01

The current article examines the history of therapeutic response in the Israel Defense Forces toward combat stress reaction during two decades, and in the course of three wars: the 1948 War of Independence, the 1956 Sinai Campaign, and the 1967 Six Day War. Three independent sources were used: recorded debriefing materials; interviews conducted with therapists, commanders and military historians; and professional literature on the wars in Hebrew and other languages. The collected material is described and issues of attitudes, treatment approaches and preparedness are discussed.

Spherical Slepian as a new method for ionospheric modeling in arctic region

Science.gov (United States)

Etemadfard, Hossein; Hossainali, Masoud Mashhadi

2016-03-01

From the perspective of the physical, chemical and biological balance in the world, the Arctic has gradually turned into an important region opening ways for new researchers and scientific expeditions. In other words, various researches have been funded in order to study this frozen frontier in details. The current study can be seen in the same milieu where researchers intend to propose a set of new base functions for modeling ionospheric in the Arctic. As such, to optimize the Spherical Harmonic (SH) functions, the spatio-spectral concentration is applied here using the Slepian theory that was developed by Simons. For modeling the ionosphere, six International GNSS Service (IGS) stations located in the northern polar region were taken into account. Two other stations were left out for assessing the accuracy of the proposed model. The adopted GPS data starts at DOY 69 (Day of Year) and ends at DOY 83 (totally 15 successive days) in 2013. Three Spherical Slepian models respectively with the maximal degrees of K=15, 20 & 25 were used. Based on the results, K=15 is the optimum degree for the proposed model. The accuracy and precision of the Slepian model are about 0.1 and 0.05 TECU, respectively (TEC Unit=1016 electron/m2). To understand the advantage of this model, it is compared with polynomial and trigonometric series which are developed using the same set of measurements. The accuracy and precision of trigonometric and polynomial models are at least 4 times worse than the Slepian one.

Agreement between the Skin Prick Test and Specific Serum IgE for Egg White and Cow's Milk Allergens in Young Infant with Atopic Dermatitis

Directory of Open Access Journals (Sweden)

Hyeon-Jong Yang

2014-01-01

Conclusions: The results of SPT agreed well with those of sIgE. This finding provides a rationale for using SPT, and suggests that SPT can be used along with sIgE to detect food sensitization in young infants with AD.

A Comparison of Cosmological Parameters Determined from CMB Temperature Power Spectra from the South Pole Telescope and the Planck Satellite

Science.gov (United States)

Aylor, K.; Hou, Z.; Knox, L.; Story, K. T.; Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Cho, H.-M.; Chown, R.; Crawford, T. M.; Crites, A. T.; de Haan, T.; Dobbs, M. A.; Everett, W. B.; George, E. M.; Halverson, N. W.; Harrington, N. L.; Holder, G. P.; Holzapfel, W. L.; Hrubes, J. D.; Keisler, R.; Lee, A. T.; Leitch, E. M.; Luong-Van, D.; Marrone, D. P.; McMahon, J. J.; Meyer, S. S.; Millea, M.; Mocanu, L. M.; Mohr, J. J.; Natoli, T.; Omori, Y.; Padin, S.; Pryke, C.; Reichardt, C. L.; Ruhl, J. E.; Sayre, J. T.; Schaffer, K. K.; Shirokoff, E.; Staniszewski, Z.; Stark, A. A.; Vanderlinde, K.; Vieira, J. D.; Williamson, R.

2017-11-01

The Planck cosmic microwave background temperature data are best fit with a ΛCDM model that mildly contradicts constraints from other cosmological probes. The South Pole Telescope (SPT) 2540 {\\deg }2 SPT-SZ survey offers measurements on sub-degree angular scales (multipoles 650≤slant {\\ell }≤slant 2500) with sufficient precision to use as an independent check of the Planck data. Here we build on the recent joint analysis of the SPT-SZ and Planck data in Hou et al. by comparing ΛCDM parameter estimates using the temperature power spectrum from both data sets in the SPT-SZ survey region. We also restrict the multipole range used in parameter fitting to focus on modes measured well by both SPT and Planck, thereby greatly reducing sample variance as a driver of parameter differences and creating a stringent test for systematic errors. We find no evidence of systematic errors from these tests. When we expand the maximum multipole of SPT data used, we see low-significance shifts in the angular scale of the sound horizon and the physical baryon and cold dark matter densities, with a resulting trend to higher Hubble constant. When we compare SPT and Planck data on the SPT-SZ sky patch to Planck full-sky data but keep the multipole range restricted, we find differences in the parameters n s and {A}s{e}-2τ . We perform further checks, investigating instrumental effects and modeling assumptions, and we find no evidence that the effects investigated are responsible for any of the parameter shifts. Taken together, these tests reveal no evidence for systematic errors in SPT or Planck data in the overlapping sky coverage and multipole range and at most weak evidence for a breakdown of ΛCDM or systematic errors influencing either the Planck data outside the SPT-SZ survey area or the SPT data at {\\ell }> 2000.

Development of a novel recessive genetic male sterility system for hybrid seed production in maize and other cross-pollinating crops.

Science.gov (United States)

Wu, Yongzhong; Fox, Tim W; Trimnell, Mary R; Wang, Lijuan; Xu, Rui-Ji; Cigan, A Mark; Huffman, Gary A; Garnaat, Carl W; Hershey, Howard; Albertsen, Marc C

2016-03-01

We have developed a novel hybridization platform that utilizes nuclear male sterility to produce hybrids in maize and other cross-pollinating crops. A key component of this platform is a process termed Seed Production Technology (SPT). This process incorporates a transgenic SPT maintainer line capable of propagating nontransgenic nuclear male-sterile lines for use as female parents in hybrid production. The maize SPT maintainer line is a homozygous recessive male sterile transformed with a SPT construct containing (i) a complementary wild-type male fertility gene to restore fertility, (ii) an α-amylase gene to disrupt pollination and (iii) a seed colour marker gene. The sporophytic wild-type allele complements the recessive mutation, enabling the development of pollen grains, all of which carry the recessive allele but with only half carrying the SPT transgenes. Pollen grains with the SPT transgenes exhibit starch depletion resulting from expression of α-amylase and are unable to germinate. Pollen grains that do not carry the SPT transgenes are nontransgenic and are able to fertilize homozygous mutant plants, resulting in nontransgenic male-sterile progeny for use as female parents. Because transgenic SPT maintainer seeds express a red fluorescent protein, they can be detected and efficiently separated from seeds that do not contain the SPT transgenes by mechanical colour sorting. The SPT process has the potential to replace current approaches to pollen control in commercial maize hybrid seed production. It also has important applications for other cross-pollinating crops where it can unlock the potential for greater hybrid productivity through expanding the parental germplasm pool. © 2015 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

Laparoscopic vs open distal pancreatectomy for solid pseudopapillary tumor of the pancreas

Science.gov (United States)

Zhang, Ren-Chao; Yan, Jia-Fei; Xu, Xiao-Wu; Chen, Ke; Ajoodhea, Harsha; Mou, Yi-Ping

2013-01-01

AIM: To compare short- and long-term outcomes of laparoscopic vs open distal pancreatectomy for solid pseudopapillary tumor (SPT) of the pancreas. METHODS: This retrospective study included 28 patients who underwent distal pancreatectomy for SPT of the pancreas between 1998 and 2012. The patients were divided into two groups based on the surgical approach: the laparoscopic surgery group and the open surgery group. The patients’ demographic data, operative results, pathological reports, hospital courses, morbidity and mortality, and follow-up data were compared between the two groups. RESULTS: Fifteen patients with SPT of the pancreas underwent laparoscopic distal pancreatectomy (LDP), and 13 underwent open distal pancreatectomy (ODP). Baseline characteristics were similar between the two groups except for a female predominance in the LDP group (100.0% vs 69.2%, P = 0.035). Mortality, morbidity (33.3% vs 38.5%, P = 1.000), pancreatic fistula rates (26.7% vs 30.8%, P = 0.728), and reoperation rates (0.0% vs 7.7%, P = 0.464) were similar in the two groups. There were no significant differences in the operating time (171 min vs 178 min, P = 0.755) between the two groups. The intraoperative blood loss (149 mL vs 580 mL, P = 0.002), transfusion requirement (6.7% vs 46.2%, P = 0.029), first flatus time (1.9 d vs 3.5 d, P = 0.000), diet start time (2.3 d vs 4.9 d, P = 0.000), and postoperative hospital stay (8.1 d vs 12.8 d, P = 0.029) were significantly less in the LDP group than in the ODP group. All patients had negative surgical margins at final pathology. There were no significant differences in number of lymph nodes harvested (4.6 vs 6.4, P = 0.549) between the two groups. The median follow-up was 33 (3-100) mo for the LDP group and 45 (17-127) mo for the ODP group. All patients were alive with one recurrence. CONCLUSION: LDP for SPT has short-term benefits compared with ODP. Long-term outcomes of LDP are similar to those of ODP. PMID:24115826

The role of spectrophotometry in the diagnosis of melanoma

Science.gov (United States)

2010-01-01

Background Spectrophotometry (SPT) could represent a promising technique for the diagnosis of cutaneous melanoma (CM) at earlier stages of the disease. Starting from our experience, we further assessed the role of SPT in CM early detection. Methods During a health campaign for malignant melanoma at National Cancer Institute of Naples, we identified a subset of 54 lesions to be addressed to surgical excision and histological examination. Before surgery, all patients were investigated by clinical and epiluminescence microscopy (ELM) screenings; selected lesions underwent spectrophotometer analysis. For SPT, we used a video spectrophotometer imaging system (Spectroshade® MHT S.p.A., Verona, Italy). Results Among the 54 patients harbouring cutaneous pigmented lesions, we performed comparison between results from the SPT screening and the histological diagnoses as well as evaluation of both sensitivity and specificity in detecting CM using either SPT or conventional approaches. For all pigmented lesions, agreement between histology and SPT classification was 57.4%. The sensitivity and specificity of SPT in detecting melanoma were 66.6% and 76.2%, respectively. Conclusions Although SPT is still considered as a valuable diagnostic tool for CM, its low accuracy, sensitivity, and specificity represent the main hamper for the introduction of such a methodology in clinical practice. Dermoscopy remains the best diagnostic tool for the preoperative diagnosis of pigmented skin lesions. PMID:20707921

Regional and local planning implications of energy policy: lessons from the past and issues from the future. [UK; 1967 to 1986

Energy Technology Data Exchange (ETDEWEB)

Roberts, P.W.

1986-01-01

This paper firstly examines the development of UK energy policy from 1967 to 1986; emphasis is placed upon the changing position of the coal industry, this section concludes with a consideration of the most recent energy forecasts. Following a brief examination of the relationships between energy and the regions, the paper looks in some detail at the changing patterns of coal production and employment in the UK regions. This leads to a consideration of the links between coal mining and the planning system: particular emphasis is placed upon the environmental, social and economic impacts of mining. The paper concludes with an examination of some of the key issues which may confront UK coal and the role of the coal industry in the process of regional development. 82 refs.

As the Child Reads: The Treatment of Minorities in Textbooks and Other Teaching Materials. Conference Report, National NEA-PR&R Conference on Civil and Human Rights in Education (Washington, D. C., February 8-10, 1967).

Science.gov (United States)

Hart, Elinor, Ed.

The conference on "The Treatment of Minorities in Textbooks and Other Teaching Materials" was held on February 8-10, 1967 in Washington, D.C. It was sponsored by the National Education Association and the Committee on Civil and Human Rights of Educators of the Commission on Professional Rights and Responsibilities. Attending the conference were…

The Role of Social Perspective-Taking in Developing Students' Leadership Capacities

Science.gov (United States)

Dugan, John P.; Bohle, Christopher W.; Woelker, Lindsey R.; Cooney, Matthew A.

2014-01-01

This study examined relationships between social perspective-taking (SPT) and the individual, group, and societal domains of socially responsible leadership. SPT is a higher-order cognitive skill linked to moral development and social coordination, but never empirically connected to leadership development. Analyses determined SPT has a strong…

The Impossible Performance of Mass Commodity. George Maciunas, Herman Fine and Robert Watts’ Implosions Inc. (ca. 1967

Directory of Open Access Journals (Sweden)

Estella Noriega, Iñaki

2016-12-01

Full Text Available In the US context Fluxus is understood as an advance of the ‘60s radicalism. The assumption that Fluxus was opposed to consumption culture, as that embodied by Pop art, is among the interpretations that renew such a view. Examining the example of Implosions Inc., a short-lived but nevertheless interesting commercial enterprise formed by Robert Watts, Herman Fine and George Maciunas in 1967, this essay focuses its attention on the complex relationship between Fluxus and commercial culture. Implosions Inc. was a project in which many Pop artists were asked to participate along with its Fluxus founders, and it was intended as another step forward in the transformation of the artist into a commodity mass-producer. In analyzing this phenomenon, this article questions assumed principles in the Neo-avantgarde theory like the distinction between art production and culture consumption. The essay, however, will try to establish another paradigm that draws the differences between Pop art and Fluxus as the kind of audiences both these tendencies tried to conform. As a conclusion, the article fleshes out some ideas on individualism that were developed by Maciunas, which shed light on the notions surrounding the idea of collectivism as developed in Fluxus.En el contexto de los EE.UU., Fluxus ha sido entendido como avanzadilla del radicalismo de la década de los 60. La asunción de que Fluxus se oponía a la cultura comercial, tal y como era representada por el pop art, es una de las líneas que renueva dicha interpretación. Mediante el análisis de Implosions Inc., una pequeña pero fundamental empresa de Fluxus que formaron en 1967 George Maciunas, Robert Watts y Herman Fine, este ensayo pretende mostrar colaboraciones entre los artistas Fluxus y Pop y que se propuso hacer del artista un productor de mercancía de masas. Al analizar este episodio, el artículo cuestiona principios de la teoría de la neovanguardia, como la distinción entre el arte de la

Solid pseudopapillary tumors of the pancreas: 27 cases from a single institution

Directory of Open Access Journals (Sweden)

ZHOU Haiyang

2013-01-01

Full Text Available ObjectiveTo summarize the clinicopathologic features and treatment outcomes of solid pseudopapillary tumors (SPTs of the pancreas. MethodsTwenty-seven cases of SPT of the pancreas admitted for treatment to the Peking University Cancer Hospital between September 2008 and September 2012 were retrospectively analyzed. ResultsThe majority of the pancreatic SPT patients were young adults (median age: 29 years old and females (85.2%. All 27 patients were treated with surgical resection using pancreaticoduodenectomy (n=4, duodenum preserving pancreatic tumor resection (n=6, middle pancreatectomy (n=5, distal pancreatectomy (n=5, or distal pancreatectomy plus splenectomy (n=7. The minimum tumor diameter was 1.5 cm, the maximum diameter was 12.0 cm, and the average diameter was 5.4 cm. Twelve patients developed pancreatic leakage and pyrexia following the operation. One patient suffered splenic artery hemorrhage. All 27 patients survived and completed follow-up. Only one patient developed recurrence, which was treated by a second surgical resection, and all other patients showed no clinical signs of recurrence or metastasis. ConclusionSPT of the pancreas has uncertain malignant potential with good prognosis. Radical resection with preservation of the surrounding tissues is an effective and safe treatment for SPT.

Atopy risk factors at birth and in adulthood.

Science.gov (United States)

Ferraz, Erica; Garcia, Clécia Aparecida; Bettiol, Heloísa; Caldeira, Roseane Durães; Cardoso, Viviane Cunha; Arruda, Luiza Karla; Barbieri, Marco Antônio; Vianna, Elcio Oliveira

2011-01-01

To study the association between atopy and variables such as weight, length, and socioeconomic level at birth and in young adulthood. A total of 2,063 subjects were investigated in a prospective birth cohort study of individuals born in Ribeirão Preto, Brazil, in 1978/1979, and examined at the age of 23-25 years. Skin prick tests (SPT) for eight common allergens in Brazil were performed. Subjects with a wheal reaction ≥ 3 mm to one or more of the eight allergens tested were considered to be atopic. We used the log-binomial model (generalized linear model) in order to assess the association between atopy and birth or adult variables. The prevalence of positive SPT was 47.6%. Male gender was associated with an increased risk of atopy (relative risk [RR] = 1.18; 95% confidence interval [95%CI] 1.07-1.30). Low level of schooling was a protective factor against atopy, with a RR = 0.74; 95%CI 0.62-0.89. Living with a smoker in childhood was also associated with lower risk of atopy (RR = 0.87; 95%CI 0.79-0.96). Birth weight, length and order, maternal age, and intrauterine growth restriction were not associated with positive SPT. This study showed that male gender was associated with an increased risk of atopy. Low socioeconomic status, assessed by low level of schooling, was a protective factor against atopy. These data agree with the hygiene hypothesis.

Army Sustainment. Volume 47, Number 6. November-December 2015

Science.gov (United States)

2015-11-01

SP TBD AWT/ AVN T: SPT Convoy GOLD / 13B SP 1315 / 1415 T: SPT Convoy Turani SP 1115 T: SPT Convoy GOLD / 13B SP 1315 / 1415 T: SPT Convoy Turani SP...white Ford observed). Legend A/DACG = Arrival/departure airfield control group AWT/ AVN = Air weapons teams/aviation BSA = Brigade support area...Tech AED Engineer AMCOM LAR AMCOM LAR AMCOM LAR AMCOM UAS LAR PM UAS Lead TACOM LAR AMCOM LAR AMCOM LAR CECOM AVN LAR AMCOM LAR PM UAS CECOM AVN LAR

Radiochemical quality of water in the shallow aquifer in Mortandad Canyon, 1967-1978

International Nuclear Information System (INIS)

Purtymun, W.D.; Hansen, W.R.; Peters, R.J.

1983-03-01

Mortandad Canyon receives treated industrial liquid effluents that contain trace amounts of radionuclides. The effluents, other waste water, and storm runoff recharge a shallow aquifer in the alluvium of the canyon. The aquifer lies within the Los Alamos National Laboratory boundaries. Analyses for gross alpha, gross beta, 137 Cs, 238 Pu, 239 Pu, 241 Am, 90 Sr, 3 H, and total U have been made of water in the aquifer from 1967 through 1978. Average concentrations of the radionuclides in solution decrease downgradient in the canyon with the exception of 3 H. Average 3 H concentrations were highest in the Middle Canyon. Inventories of most radionuclides in the water indicate that in 1978 less than 1% of the total amount released with the effluents in the canyon from 1963 through 1978 remained in solution. The amount of total U in solution in 1978 was about 16% of the total amount released. If there is no significant change in the amounts of radionuclides received at the treatment plant and methods of treatment remain the same, the projected estimates of radionuclide concentrations in the aquifer will increase about 80% from 1978 to 1990. The average concentrations in 1978 and projected concentrations in 1990 of gross alpha, 137 Cs, 238 Pu, 239 Pu, 241 Am, 90 Sr, 3 H, and total U are less than 1% of the Department of Energy's concentration guides (CG) for areas with controlled public access. Gross beta radioactivity in 1978 was 2% of the CG and is projected to increase to 3% of the CG by 1990

Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells.

Science.gov (United States)

Safina, Alfiya; Garcia, Henry; Commane, Mairead; Guryanova, Olga; Degan, Seamus; Kolesnikova, Kateryna; Gurova, Katerina V

2013-08-01

Facilitates chromatin transcription (FACT) is a chromatin remodeling complex with two subunits: SSRP1 and SPT16. Mechanisms controlling FACT levels are of interest, since the complex is not expressed in most differentiated cells, but is frequently upregulated in cancer, particularly in poorly differentiated, aggressive tumors. Moreover, inhibition of FACT expression or function in tumor cells interferes with their survival. Here we demonstrate that SSRP1 and SPT16 protein levels decline upon induction of cellular differentiation or senescence in vitro and that similar declines in protein levels for both SSRP1 and SPT16 occur upon RNAi-mediated knockdown of either SSRP1 or SPT16. The interdependence of SSRP1 and SPT16 protein levels was found to be due to their association with SSRP1 and SPT16 mRNAs, which stabilizes the proteins. In particular, presence of SSRP1 mRNA is critical for SPT16 protein stability. In addition, binding of SSRP1 and SPT16 mRNAs to the FACT complex increases the stability and efficiency of translation of the mRNAs. These data support a model in which the FACT complex is stable when SSRP1 mRNA is present, but quickly degrades when SSRP1 mRNA levels drop. In the absence of FACT complex, SSRP1 and SPT16 mRNAs are unstable and inefficiently translated, making reactivation of FACT function unlikely in normal cells. Thus, we have described a complex and unusual mode of regulation controlling cellular FACT levels that results in amplified and stringent control of FACT activity. The FACT dependence of tumor cells suggests that mechanisms controlling FACT levels could be targeted for anticancer therapy.

Analysis of Energy Resources and Programs of the Soviet Union and Eastern Europe. Appendix F: Electric Power

Science.gov (United States)

1973-12-01

Chirchik 0.60 1963-1967 6’j Irkutskaiya Angara 0.66 1950-1956 91 Pliyvinskaiya Daugava 0.83 1961-1966 49 Chirkeiskaiya Sulak 1.00 1963-1967 36...Chirkeisk station on the River Sulak . Some of the others, such as the Irgurskaiya (Inguri River), are being built with a total head of 271 meters

Energetically benign synthesis of lanthanum silicate through “silica garden” route and its characterization

Energy Technology Data Exchange (ETDEWEB)

Parmar, Kavita [Central University of Jharkhand, Ranchi (India); Bhattacharjee, Santanu, E-mail: santanu@nmlindia.org [CSIR-National Metallurgical Laboratory, Jamshedpur (India)

2017-06-15

Lanthanum silicate synthesis through “silica garden” route has been reported as an alternative to energy intensive milling procedure. Under optimum conditions lanthanum chloride crystals react with water glass (sodium silicate) to produce self generating hollow lanthanum silicate precipitation tube(s) (LaSPT). The micro tubes are irregular, thick, white coloured and amorphous but are hierarchically built from smaller tubules of 10–20 nm diameters. They retain their amorphous nature on being heated up to 600 °C beyond which crystallization starts. The major phase in the LaSPT heated at 900 °C is La{sub 2}Si{sub 2}O{sub 7}. “As synthesized” LaSPT is heterogeneous and comprises non stoichiometric phases. The exterior and interior surfaces of these tubes are remarkably different in their morphology and chemical composition. LaSPT sintered at 1200 and 1300 °C show fair amount of ionic conductivity. - Graphical abstract: Lanthanum silicate precipitation tube (LaSPT) produced through ‘silica garden’ route offers a green alternative to energy intensive milling procedure. - Highlights: • La-silicate precipitation tube (LaSPT) synthesized via silica garden route. • The microtubes are irregular, thick, white coloured and amorphous. • They are hierarchically built from smaller tubules of 10–20 nm diameters. • The major phase in the LaSPT heated at 900 °C is La{sub 2}Si{sub 2}O{sub 7}. • LaSPT sintered at 1200 °C is fairly conducting.

Energetically benign synthesis of lanthanum silicate through “silica garden” route and its characterization

International Nuclear Information System (INIS)

Parmar, Kavita; Bhattacharjee, Santanu

2017-01-01

Lanthanum silicate synthesis through “silica garden” route has been reported as an alternative to energy intensive milling procedure. Under optimum conditions lanthanum chloride crystals react with water glass (sodium silicate) to produce self generating hollow lanthanum silicate precipitation tube(s) (LaSPT). The micro tubes are irregular, thick, white coloured and amorphous but are hierarchically built from smaller tubules of 10–20 nm diameters. They retain their amorphous nature on being heated up to 600 °C beyond which crystallization starts. The major phase in the LaSPT heated at 900 °C is La_2Si_2O_7. “As synthesized” LaSPT is heterogeneous and comprises non stoichiometric phases. The exterior and interior surfaces of these tubes are remarkably different in their morphology and chemical composition. LaSPT sintered at 1200 and 1300 °C show fair amount of ionic conductivity. - Graphical abstract: Lanthanum silicate precipitation tube (LaSPT) produced through ‘silica garden’ route offers a green alternative to energy intensive milling procedure. - Highlights: • La-silicate precipitation tube (LaSPT) synthesized via silica garden route. • The microtubes are irregular, thick, white coloured and amorphous. • They are hierarchically built from smaller tubules of 10–20 nm diameters. • The major phase in the LaSPT heated at 900 °C is La_2Si_2O_7. • LaSPT sintered at 1200 °C is fairly conducting.

The prevalence of skin-test-positive allergic rhinitis in Danish adults

DEFF Research Database (Denmark)

Linneberg, A; Jørgensen, T; Nielsen, N H

2000-01-01

BACKGROUND: It is disputed whether increases in self-reported respiratory allergy represent a true increase or merely increased recognition. We aimed to investigate whether the prevalence of skin-prick-test (SPT)-positive allergic rhinitis had increased in an adult general population in Copenhagen...... (participation rate 74.6%) and 482 (participation rate 53.4%) subjects were examined in 1990 and 1998, respectively. Diagnoses of SPT-positive allergic rhinitis were based on a history of nasal symptoms on exposure to allergens and SPT positivity to allergens. RESULTS: The prevalence of a diagnosis of SPT...

Use of dye tracing in water-resources investigations in Wyoming, 1967-94

Science.gov (United States)

Wilson, J.F.; Rankl, J.G.

1996-01-01

During 1967-94, the U.S. Geological Survey made numerous applications of dye tracing for water-resources investigations in Wyoming. Many of the dye tests were done in cooperation with other agencies. Results of all applications, including some previously unpublished, are described. A chronology of past applications in Wyoming and a discussion of potential future applications are included. Time-of-travel and dispersion measurements were made in a 113-mile reach of the Wind/Bighorn River below Boysen Dam; a 117-mile reach of the Green River upstream from Fontenelle Reservoir and a 70-mile reach downstream; parts of four tributaries to the Green (East Fork River, 39 miles; Big Sandy River, 112 miles; Horse Creek, 14 miles; and Blacks Fork, 14 miles); a 75-mile reach of the Little Snake River along the Wyoming-Colorado State line; and a 95-mile reach of the North Platte River downstream from Casper. Reaeration measurements were made during one of the time-of-travel measurements in the North Platte River. Sixty-eight dye-dilution measurements of stream discharge were made at 22 different sites. These included 17 measurements for verifying the stage-discharge relations for streamflow-gaging stations on North and South Brush Creeks near Saratoga, and total of 29 discharge measurements at 12 new stations at remote sites on steep, rough mountain streams crossing limestone outcrops in northeastern Wyoming. The largest discharge measured by dye tracing was 2,300 cubic feet per second. In karst terrane, four losing streams-North Fork Powder River, North Fork Crazy Woman Creek, Little Tongue River, and Smith Creek-were dye-tested. In the Middle Popo Agie River, a sinking stream in Sinks Canyon State Park, a dye test verified the connection of the sink (Sinks of Lander Cave) to the rise, where flow in the stream resumes.

Italian Mass Media and the Atom in the 1960s: The Memory of Hiroshima and Nagasaki and the Peaceful Atom (1963-1967)

International Nuclear Information System (INIS)

Ciglioni, Laura

2017-01-01

The chapter investigates the representations of both fears and hopes related to atomic issues in Italian mass media from 1963 to 1967, through the analysis of a selection of highly circulated mass-market magazines (representing a broad spectrum of political cultures) and of television programs broadcast by the two Italian public networks of the time. The fears of the “atomic age” are analyzed through the memory of Hiroshima and Nagasaki, which represents one of the privileged venues for both molding representations of the atomic bomb and negotiating fears. “Atomic hopes” are investigated, instead, examining the emergent fascination for the peaceful uses of atomic energy, analyzed as the catalyst for a positive perception of the atom at a time when national energy policies were at a crucial turning point.

Does Nintendo Wii Balance Board improve standing balance? A randomized controlled trial in children with cerebral palsy.

Science.gov (United States)

Gatica-Rojas, Valeska; Méndez-Rebolledo, Guillermo; Guzman-Muñoz, Eduardo; Soto-Poblete, Alex; Cartes-Velásquez, Ricardo; Elgueta-Cancino, Edith; Cofré Lizama, L Eduardo

2017-08-01

Evidence on the effect of systemic exercise programs to improve the standing balance with the Nintendo Wii system is very limited and its post-treatment effectiveness is unknown in cerebral palsy (CP) patients. Primary aim was to compare the effect of Nintendo Wii balance board (Wii-therapy) and standard physiotherapy (SPT), on the performance of standing balance in children and adolescents with CP. Secondary aim was to determine the post-treatment effectiveness of Wii-therapy and SPT. Two-arm, matched-pairs, parallel-groups, randomized, controlled clinical trial. Outpatient Rehabilitation Centre in the city of Talca. Patients with CP type spastic hemiplegia (SHE) and spastic diplegia (SDI), aged 7 to 14 years, and level I or II of GMFCS or GMFCS-ER. Were excluded patients with FSIQWii-therapy (SDI=7; SHE=9) or SPT intervention (SDI=7; SHE=9). In each group, patients received three sessions per week over a period of 6 weeks. Standing balance was assessed at baseline and every 2 weeks. Additionally, two follow-up assessments (4 additional weeks) were performed to determine post-treatment effectiveness. Standing balance was quantified on force platform obtaining the outcomes area of center-of-pressure (CoP) sway (CoPSway), standard deviation in the medial-lateral (SDML) and the anterior-posterior (SDAP) directions, and velocity in both directions (VML and VAP). Compared to SPT, Wii-therapy significantly reduced the CoPSway (P=0.02) and SDAP in the eyes-open condition (P=0.01). However, the effects wane after 2-4 weeks. Post-hoc analysis revealed that only SHE children benefited from Wii-therapy. Wii-therapy was better than SPT in improving standing balance in patients with CP, but improves the balance only in SHE patients. Also, Wii-therapy effectiveness waned 2-4 weeks after the end the intervention. A systematic exercise program like Wii-therapy using the Nintendo Wii Balance Board device can be considered to improves the standing balance in patients with CP

Double-blind, randomized phase 3 trial of low-dose 13-cis retinoic acid in the prevention of second primaries in head and neck cancer: Long-term follow-up of a trial of the Eastern Cooperative Oncology Group-ACRIN Cancer Research Group (C0590).

Science.gov (United States)

Bhatia, Aarti K; Lee, Ju-Whei; Pinto, Harlan A; Jacobs, Charlotte D; Limburg, Paul J; Rubin, Philip; Arusell, Robert M; Dunphy, Eamonn P; Khandekar, Janardan D; Reiner, Seth A; Baez-Diaz, Luis; Celano, Paul; Li, Shuli; Li, Yi; Burtness, Barbara A; Adams, George L; Pandya, Kishan J

2017-12-01

13-Cis retinoic acid (13-CRA) is a synthetic vitamin A derivative. High-dose 13-CRA in patients with squamous cell cancers of the head and neck (SCCHNs) reduces the incidence of second primary tumors (SPTs). The authors report long-term results from a phase 3 randomized trial that compared treatment with low-dose 13-CRA versus placebo for patients who had early stage SCCHN, with a focus on the development of SPTs and overall survival (OS). In total, 176 patients who received treatment for stage I/II SCCHN were randomized to receive either low-dose 13-CRA (weight-based dose of 7.5 mg or 10 mg) or placebo for 2 years. A competing-risk approach and the log-rank test were used to compare the time to SPT and OS, respectively, between groups. 13-CRA neither significantly reduced the cumulative incidence of SPT (P = .61) nor improved the time to SPT (hazard ratio [HR] for 13-CRA/placebo; 0.86; P = .61). Despite limited power, there was a trend toward improved OS for the 13-CRA arm (HR, 0.75; P = .14), particularly among patients whose index tumor was surgically excised (N = 26; HR, 0.50; P = .057) and among women (N = 39; HR, 0.44; P = .065) and never/former smokers (N = 129; HR, 0.61; P = .055), with a median follow-up of 16 years. The main 13-CRA related toxicities were dry skin and cheilitis. Treatment with low-dose 13-CRA for 2 years did not decrease the incidence of SPT; subset analysis indicates a potential survival advantage among patients who are women and never/former smokers. More targeted interventions based on clinical risk factors and molecular characterization of tumors may yield greater success in future prevention trials. Cancer 2017;123:4653-4662. © 2017 American Cancer Society. © 2017 American Cancer Society.

Inhibition of serine palmitoyltransferase in vitro and long-chain base biosynthesis in intact Chinese hamster ovary cells by β-Cl-alanine

International Nuclear Information System (INIS)

Medlock, K.A.; Merrill, A.H. Jr.

1987-01-01

Serine palmitoyltransferase (SPT) is a pyridoxal-5'-phosphate dependent enzyme that catalyzes the first committed step of long-chain base (LCB) synthesis. Inhibition of SPT activity and de novo biosynthesis of sphinganine and sphingosine was observed in vitro and in intact Chinese hamster ovary cells (CHO). In vitro studies revealed that inhibition was irreversible and concentration- and time-dependent, which are characteristics of suicide inhibition. Incubation of intact CHO cells with 5 mM β-Cl-alanine for 15 min completely inhibited SPT activity and LCB synthesis from [ 14 C]serine. The concentration dependences of inhibition of SPT activity and LCB formation were identical. There was no loss of viability of recovery of SPT activity over the 2 hour time course of these experiments. The synthesis of several other lipids was not affected by the same treatment. These results establish the association between the activity of SPT and the cellular rate of LCB formation and indicate that β-Cl-alanine can be used to study alterations in cellular LCB synthesis

Levendefødte i Norge 1967-76 med diagnosen Down syndrom – en registerstudie

Directory of Open Access Journals (Sweden)

Tor Bjerkedal

2009-10-01

Full Text Available Diagnoser av Down syndrom registrert i Medisinsk fødselsregister (MFR er sammenholdt med diagnoser registrert i stønadsregistrene i Ny arbeids- og velferdsetat (NAV, tidligere Rikstrygdeverket for alle levendefødte i årene 1967-76, i alt 629 928. Formålet med studien har vært å vurdere hvor ofte diagnosen Down syndrom registreres i MFR i forhold til forekomsten av tilstanden og validiteten av diagnosene, og å følge opp sannsynlige tilfeller av Down syndrom til ung voksen alder i forhold til overlevelse, utdanning, arbeidsaktivitet, uførepensjonering og familiedannelse. Oppfølgingen er muliggjort ved registerkoblinger, godkjent av Datatilsynet og utført av Statistisk sentralbyrå. Totalt var diagnosen Down syndrom registrert i 784 tilfeller, 1,25 per 1000 levendefødte, noe høyere for gutter, 1,31, enn for piker 1,19. Falske positive i MFR utgjorde 4,9 prosent mens falske negative er anslått til 27,8 prosent. Det vil si at 72,2 prosent av Down syndrom tilfellene blir diagnostisert ved fødsel og registrert i MFR. Dette anslag er beheftet med atskillig usikkerhet. Usikkerheten skyldes omfanget av fosterindisert abort, uensartet diagnostikk, varierende meldefrekvens og mangelfull registrering. Å redusere usikkerheten ville kreve systematisk tilgang til relevante helseregistre og at helsevesenets samlede kunnskap om personer med definerte lidelser kan innhentes løpende. Personvern, slik dette forståes og praktiseres i dag, vil sannsynligvis hindre en slik løsning. En systematisk oppfølging er imidlertid viktig for velferden for utsatte grupper i vårt samfunn. I foreliggende undersøkelse kan det dokumenteres at personer med Down syndrom ikke oppnår den arbeidsaktivitet som utdanningen de har gjennomført skulle tilsi. At noen få tilfeller ikke synes å være uførepensjonert før 30-års alderen kan også være et interessant funn. En avklaring på dette forhold kunne gi nyttig informasjon for velferdsarbeidet for personer med

Why Sustainers Should Care About the Targeting Process

Science.gov (United States)

2016-02-29

1200 T: Recon GOLD / 13B SP TBD AWT/ AVN T: SPT Convoy GOLD / 13B SP 1315 / 1415 T: SPT Convoy Turani SP 1115 T: SPT Convoy GOLD / 13B SP 1315 / 1415 T...on the lookout for a white Ford observed). Legend A/DACG = Arrival/departure airfield control group AWT/ AVN = Air weapons teams/aviation BSA

A sandwiched piezoelectric transducer with flex end-caps for energy harvesting in large force environments

International Nuclear Information System (INIS)

Kuang, Yang; Daniels, Alice; Zhu, Meiling

2017-01-01

This paper presents a sandwiched piezoelectric transducer (SPT) for energy harvesting in large force environments with increased load capacity and electric power output. The SPT uses (1) flex end-caps to amplify the applied load force so as to increase its power output and (2) a sandwiched piezoelectric-substrate structure to reduce the stress concentration in the piezoelectric material so as to increase the load capacity. A coupled piezoelectric-circuit finite element model (CPC-FEM) was developed, which is able to directly predict the electric power output of the SPT connected to a load resistor. The CPC-FEM was used to study the effects of various parameters of the SPT on the performance to obtain an optimal design. These parameters included the substrate thickness, the end-cap material and thickness, the electrode length, the joint length, the end-cap internal angle and the PZT thickness. A prototype with optimised parameters was tested on a loading machine, and the experimental results were compared with simulation. A good agreement was observed between simulation and experiment. When subjected to a 1 kN 2 Hz sinusoidal force applied by the loading machine, the SPT produced an average power of 4.68 mW. The application of the SPT as a footwear energy harvester was demonstrated by fitting the SPT into a boot and performing the tests on a treadmill, and the SPT generated an average power of 2.5 mW at a walking speed of 4.8 km h −1 . (paper)

Smoking and the development of allergic sensitization to aeroallergens in adults

DEFF Research Database (Denmark)

Linneberg, A; Nielsen, N H; Madsen, F

2001-01-01

positivity and specific IgE positivity, respectively. The risk of developing SPT positivity (adjusted odds ratio: 0.45, 95% CI 0.21-0.98) and specific IgE positivity (adjusted odds ratio: 0.62, 95%, CI 0.26-1.49) was lower among sustained smokers than never-smokers. CONCLUSIONS: In this adult population...

Kidney bean: a major sensitizer among legumes in asthma and rhinitis patients from India.

Directory of Open Access Journals (Sweden)

Ramkrashan Kasera

Full Text Available BACKGROUND: The prevalence of IgE mediated food allergies has increased over the last two decades. Food allergy has been reported to be fatal in highly sensitive individuals. Legumes are important food allergens but their prevalence may vary among different populations. The present study identifies sensitization to common legumes among Indian population, characterizes allergens of kidney bean and establishes its cross reactivity with other legumes. METHODOLOGY: Patients (n = 355 with history of legume allergy were skin prick tested (SPT with 10 legumes. Specific IgE (sIgE and total IgE were estimated in sera by enzyme-linked immunosorbent assay. Characterization of kidney bean allergens and their cross reactivity was investigated by immunobiochemical methods. Identification of major allergens of kidney bean was carried out by mass spectrometry. PRINCIPAL FINDINGS: Kidney bean exhibited sensitization in 78 (22.0% patients followed by chickpea 65 (18.0% and peanut 53 (15%. SPT positive patients depicted significantly elevated sIgE levels against different legumes (r = 0.85, p<0.0001. Sera from 30 kidney bean sensitive individuals exhibited basophil histamine release (16-54% which significantly correlated with their SPT (r = 0.83, p<0.0001 and sIgE (r = 0.99, p<0.0001. Kidney bean showed eight major allergens of 58, 50, 45, 42, 40, 37, 34 and 18 kDa on immunoblot and required 67.3±2.51 ng of homologous protein for 50% IgE inhibition. Inhibition assays revealed extensive cross reactivity among kidney bean, peanut, black gram and pigeon pea. nLC-MS/MS analysis identified four allergens of kidney bean showing significant matches with known proteins namely lectin (phytohemagglutinin, phaseolin, alpha-amylase inhibitor precursor and group 3 late embryogenesis abundant protein. CONCLUSION/SIGNIFICANCE: Among legumes, kidney bean followed by chick pea and peanut are the major allergic triggers in asthma and rhinitis patients in India

Effect of inorganic additive sodium pyrophosphate tetrabasic on positive electrolytes for a vanadium redox flow battery

International Nuclear Information System (INIS)

Park, Se-Kook; Shim, Joonmok; Yang, Jung Hoon; Jin, Chang-Soo; Lee, Bum Suk; Lee, Young-Seak; Shin, Kyoung-Hee; Jeon, Jae-Deok

2014-01-01

Sodium pyrophosphate tetrabasic (SPT) is employed as an inorganic additive in the positive electrolyte of a vanadium redox flow battery (VRFB) to improve its long-term stability and electrochemical performance. The results of precipitation tests show that the long-term stability of positive electrolytes (2 MV(V) solution in 4 M total sulfates with 0.05 M SPT additive) is improved compared to the blank one. UV-vis and cyclic voltammetry (CV) measurements also suggest that the addition of SPT can effectively delay the formation of precipitation in positive electrolytes, and no new substances are formed in V(V) electrolytes with SPT. The calcined precipitates extracted from the electrolytes with and without a SPT additive are identified as V 2 O 5 by X-ray diffraction (XRD) analysis. A VRFB single-unit cell employing positive electrolytes with an additive exhibits the high energy efficiency of 74.6% at a current density of 40 mA cm 2 at the 500 th cycle at 20°C, compared to 71.8% for the cell employing the electrolyte without an additive. Moreover, the cell employing the electrolyte with an additive exhibits less discharge capacity fading during cycling in comparison with the pristine one. The disassembled cell without an additive shows a large number of V 2 O 5 precipitation particles on the felt electrode after 500 cycles. Meanwhile, the felt electrode of the cell with an additive has little precipitation. That precipitation gives rise to an imbalance between the positive and negative half-cell electrolytes, which results in a significant capacity loss. The additive has shown positive results under limited laboratory short-term and small-scale conditions

Case studies in live electronic music preservation : Recasting Jorge Peixinho's Harmónicos (1967-1986 and Sax-Blue (1984-1992

Directory of Open Access Journals (Sweden)

António de Sousa Dias

2009-05-01

Full Text Available We present two examples of technology transfer from analogical to digital systems, in two works of live electroacoustic music by the Portuguese composer Jorge Peixinho (1940-1995, Harmónicos (1967 and Sax-Blue (1982. These works require the use of analogue technology that has become obsolete or difficult to access by the average performer. We think that migration from electronics to software, also referred as recast represents a necessary step to preserve live electroacoustic music. However, this process can pose multiple questions as it also relies on aesthetic considerations. In this case, we put on a considerable effort into understanding both the composer's intentions and the equipment operating mode and we think the solutions proposed are adequate to perform both works. Finally, we discuss some of the questions, solutions and limitations that arose with these recasts and how they can contribute to the sustainability problem concerning these works.

Computational Power of Symmetry-Protected Topological Phases.

Science.gov (United States)

Stephen, David T; Wang, Dong-Sheng; Prakash, Abhishodh; Wei, Tzu-Chieh; Raussendorf, Robert

2017-07-07

We consider ground states of quantum spin chains with symmetry-protected topological (SPT) order as resources for measurement-based quantum computation (MBQC). We show that, for a wide range of SPT phases, the computational power of ground states is uniform throughout each phase. This computational power, defined as the Lie group of executable gates in MBQC, is determined by the same algebraic information that labels the SPT phase itself. We prove that these Lie groups always contain a full set of single-qubit gates, thereby affirming the long-standing conjecture that general SPT phases can serve as computationally useful phases of matter.

Review of the Lightning Strike Incident at Launch Complex 37 on July 27, 1967, and Comparison to a Gemini Lightning Strike

Science.gov (United States)

Llewellyn, J. A.

1967-01-01

The Launch Complex 37 lightning strike of July 27, 1967, was reviewed and compared to a similar incident on the Gemini Program. Available data indicate little likelihood of damaging currents having been present in SA-204 Launch Vehicle or the ground equipment during the July 27th incident. Based on the results of subsystem and system testing after the strike, anticipated results of future testing, the six months elapsed time between the strike-and launch, and the fact that much of the critical airborne electrical/electronic equipment has been removed since the strike for other reasons, no new actions are considered necessary at this time in the Gemini case, significant failures occurred in both airborne and ground circuits. Due to the resultant semi, condlictor uncertainty, and the relatively' short time prior to planned launch, all critical airborne components containing semiconduetors were replaced, and a sophisticated data comparison task was implemented.

Small specimen technique for assessing mechanical properties of metallic components

Energy Technology Data Exchange (ETDEWEB)

Lobo, Raquel M.; Andrade, Arnaldo H.P.; Morcelli, Aparecido E., E-mail: rmlobo@ipen.br, E-mail: morcelliae@gmail.com [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

2017-11-01

Small Punch Test (SPT) is one of the most promising techniques of small specimen test, which was originally applied in testing of irradiated materials in nuclear engineering. Then it was introduced to other fields as an almost nondestructive method to measure the local mechanical properties that are difficult to be obtained using conventional mechanical tests. Most studies to date are focused on metallic materials, although SPT applications are recently spreading to other materials. The small punch test (SPT) employs small-sized specimens (for example, samples measuring 8 mm in diameter and 0.5 mm thick). The specimen is firmly clamped between two circular dies and is bi-axially strained until failure into a circular hole using a hemispherical punch. The 'load-punch displacement' record can be used to estimate the yield strength, the ultimate tensile strength, the tensile elongation, and the temperature of the ductile-to-brittle transition. Recently, some researchers are working on the use of miniature notched or pre-cracked specimens (denoted as p-SPT) to validate its geometry and dimensions for obtaining the fracture properties of metallic materials. In a first approach, the technique makes it possible to convert primary experimental data into conventional mechanical properties of a massive specimen. In this paper a comprehensive review of the different STP applications is presented with the aim of clarifying its usefulness. (author)

Nonatopic asthma is associated with helminth infections and bronchiolitis in poor children.

Science.gov (United States)

Pereira, M U; Sly, P D; Pitrez, P M; Jones, M H; Escouto, D; Dias, A C O; Weiland, S K; Stein, R T

2007-06-01

Asthma is common in urban centres in Latin America, but atopic asthma may not be the main phenotype among children. Helminth infections are highly prevalent in poor populations, and it was hypothesised that they attenuate allergic asthma, whereas other factors are related to the expression of a nonatopic wheeze/asthma phenotype. A total of 1,982 children from Southern Brazil with a mean+/-sd age of 10.1+/-0.76 yrs completed asthma questionnaires, and 1,011 were evaluated for intestinal parasites and atopy using skin-prick tests (SPTs). Wheeze in the previous 12 months was reported by 25.6%, and 9.3% showed current asthma; 13% were SPT-positive and 19.1% were positive for any helminths. Most children with either wheeze or asthma were SPT-negative; however, severe wheeze was more prevalent among the atopic minority. Helminth infections were inversely associated with positive SPT results. Bronchiolitis before the age of 2 yrs was the major independent risk factor for asthma at age 10 yrs; high-load Ascaris infection, a family history of asthma and positive SPT results were also asthma risk factors. Most asthma and wheeze are of the nonatopic phenotype, suggesting that some helminths may exert an attenuating effect on the expression of the atopic portion of the disease, whereas viral bronchiolitis predisposes more specifically to recurrent airway symptoms.

Small specimen technique for assessing mechanical properties of metallic components

International Nuclear Information System (INIS)

Lobo, Raquel M.; Andrade, Arnaldo H.P.; Morcelli, Aparecido E.

2017-01-01

Small Punch Test (SPT) is one of the most promising techniques of small specimen test, which was originally applied in testing of irradiated materials in nuclear engineering. Then it was introduced to other fields as an almost nondestructive method to measure the local mechanical properties that are difficult to be obtained using conventional mechanical tests. Most studies to date are focused on metallic materials, although SPT applications are recently spreading to other materials. The small punch test (SPT) employs small-sized specimens (for example, samples measuring 8 mm in diameter and 0.5 mm thick). The specimen is firmly clamped between two circular dies and is bi-axially strained until failure into a circular hole using a hemispherical punch. The 'load-punch displacement' record can be used to estimate the yield strength, the ultimate tensile strength, the tensile elongation, and the temperature of the ductile-to-brittle transition. Recently, some researchers are working on the use of miniature notched or pre-cracked specimens (denoted as p-SPT) to validate its geometry and dimensions for obtaining the fracture properties of metallic materials. In a first approach, the technique makes it possible to convert primary experimental data into conventional mechanical properties of a massive specimen. In this paper a comprehensive review of the different STP applications is presented with the aim of clarifying its usefulness. (author)

Dando vida me doy vida: Una experiencia de investigación acción con familias

OpenAIRE

Arce-Chavarría, Eilyn

2015-01-01

This paper is the result of a participatory action research project.  It expresses my experiences with nine of the fourteen families of students attending the special education school where I work.  Students are in Early Intervention (0-3 years old), Kinder Garden (3-6 and a half years old) and the first cycle of elementary school (6 years and 6 months to 9 years old). Six of the participating families included a father and a mother, while the other three only included the mother. I met six t...

HC/MC-130 Recapitalization Aircraft (HC/MC-130 Recap)

Science.gov (United States)

2015-12-01

rigging for aerial delivery, aeromedical and other rigging, and principles of cargo restraint for Loadmaster personnel. This allows for training without...Initial APUC Production Estimate Changes APUC Current Estimate Econ Qty Sch Eng Est Oth Spt Total 108.841 0.842 0.871 -0.756 2.167 -12.630 0.000 9.607

Braille use among Norwegian children from 1967 to 2007: trends in the underlying causes.

Science.gov (United States)

Augestad, Liv Berit; Klingenberg, Oliv; Fosse, Per

2012-08-01

The aim of the study was to estimate the occurrence, diagnoses and time trends among Norwegian children that have received education in braille from 1967 to 2007. We used a retrospective population-based study design. The health care system is free for all inhabitants in Norway. We included all children that had received braille education the last four decades. From each student's record, we abstracted year born, country of birth, gender, year diagnosed, diagnosis, classification of visual impairment and type of reading media. We identified 287 children (137 girls and 150 boys) that had received braille education over the last 40 years. Of these, 262 (91.3%) children were born in Norway, 145 (53.7%) were diagnosed within the first year of life and 59 (20.6%) from age of one to five. The most frequent diagnoses were Retinopathy of Prematurity (ROP), Juvenile Ceroid Lipofuscinoses (JNCL), Lebers Congenital Amaurosis (LCA) and Retinitis Pigmentosa (RP). Among the children, 63% (N = 170) used braille only, 9% (N = 25) braille and print, but priority braille, and 27% (N = 73) braille and print, priority print. The number of children with ROP using braille had a peak in 1977, then the number declined. The number diagnosed with LCA increased from 1987 to 1992. The number of braille users among children diagnosed with JNCL tended to increase substantially after 1992. Braille education seemed to be dependent of trends in diagnoses as well as trends in recommendations from professional educators. © 2011 The Authors. Acta Ophthalmologica © 2011 Acta Ophthalmologica Scandinavica Foundation.

Juventud rebelde, campesinado indígena y la instalación del discurso de clases en los campos de Cautín. Movimiento Campesino Revolucionario. Chile, 1967-1973

OpenAIRE

Ovidio Cárcamo Hernández

2015-01-01

El propósito de este artículo es analizar el itinerario seguido por algunos militantes del Movimiento de Izquierda Revolucionaria (MIR), en el marco de la Reforma Agraria chilena entre 1967 y 1973, en la provincia de Cautín, en el surde Chile. Además buscamos describir el proceso de vinculación entre los militantes del MIR y el campesinado indígena, relación de la cual nació el Movimiento Campesino Revolucionario (MCR) a fines de 1970, iniciándose así una importante embestida contra la gran p...

Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation.

Science.gov (United States)

Kurat, Christoph F; Lambert, Jean-Philippe; Petschnigg, Julia; Friesen, Helena; Pawson, Tony; Rosebrock, Adam; Gingras, Anne-Claude; Fillingham, Jeffrey; Andrews, Brenda

2014-09-30

DNA replication occurs during the synthetic (S) phase of the eukaryotic cell cycle and features a dramatic induction of histone gene expression for concomitant chromatin assembly. Ectopic production of core histones outside of S phase is toxic, underscoring the critical importance of regulatory pathways that ensure proper expression of histone genes. Several regulators of histone gene expression in the budding yeast Saccharomyces cerevisiae are known, yet the key oscillator responsible for restricting gene expression to S phase has remained elusive. Here, we show that suppressor of Ty (Spt)10, a putative histone acetyltransferase, and its binding partner Spt21 are key determinants of S-phase-specific histone gene expression. We show that Spt21 abundance is restricted to S phase in part by anaphase promoting complex Cdc20-homologue 1 (APC(Cdh1)) and that it is recruited to histone gene promoters in S phase by Spt10. There, Spt21-Spt10 enables the recruitment of a cascade of regulators, including histone chaperones and the histone-acetyltransferase general control nonderepressible (Gcn) 5, which we hypothesize lead to histone acetylation and consequent transcription activation.

Deficient symbol processing in Alzheimer disease.

Science.gov (United States)

Toepper, Max; Steuwe, Carolin; Beblo, Thomas; Bauer, Eva; Boedeker, Sebastian; Thomas, Christine; Markowitsch, Hans J; Driessen, Martin; Sammer, Gebhard

2014-01-01

Symbols and signs have been suggested to improve the orientation of patients suffering from Alzheimer disease (AD). However, there are hardly any studies that confirm whether AD patients benefit from signs or symbols and which symbol characteristics might improve or impede their symbol comprehension. To address these issues, 30 AD patients and 30 matched healthy controls performed a symbol processing task (SPT) with 4 different item categories. A repeated-measures analysis of variance was run to identify impact of different item categories on performance accuracy in both the experimental groups. Moreover, SPT scores were correlated with neuropsychological test scores in a broad range of other cognitive domains. Finally, diagnostic accuracy of the SPT was calculated by a receiver-operating characteristic curve analysis. Results revealed a global symbol processing dysfunction in AD that was associated with semantic memory and executive deficits. Moreover, AD patients showed a disproportional performance decline at SPT items with visual distraction. Finally, the SPT total score showed high sensitivity and specificity in differentiating between AD patients and healthy controls. The present findings suggest that specific symbol features impede symbol processing in AD and argue for a diagnostic benefit of the SPT in neuropsychological assessment.

Plant Outage Time Savings Provided by Subcritical Physics Testing at Vogtle Unit 2

International Nuclear Information System (INIS)

Cupp, Philip; Heibel, M.D.

2006-01-01

The most recent core reload design verification physics testing done at Southern Nuclear Company's (SNC) Vogtle Unit 2, performed prior to initial power operations in operating cycle 12, was successfully completed while the reactor was at least 1% ΔK/K subcritical. The testing program used was the first application of the Subcritical Physics Testing (SPT) program developed by the Westinghouse Electric Company LLC. The SPT program centers on the application of the Westinghouse Subcritical Rod Worth Measurement (SRWM) methodology that was developed in cooperation with the Vogtle Reactor Engineering staff. The SRWM methodology received U. S. Nuclear Regulatory Commission (NRC) approval in August of 2005. The first application of the SPT program occurred at Vogtle Unit 2 in October of 2005. The results of the core design verification measurements obtained during the SPT program demonstrated excellent agreement with prediction, demonstrating that the predicted core characteristics were in excellent agreement with the actual operating characteristics of the core. This paper presents an overview of the SPT Program used at Vogtle Unit 2 during operating cycle 12, and a discussion of the critical path outage time savings the SPT program is capable of providing. (authors)

Cell cycle-regulated oscillator coordinates core histone gene transcription through histone acetylation

Science.gov (United States)

Kurat, Christoph F.; Lambert, Jean-Philippe; Petschnigg, Julia; Friesen, Helena; Pawson, Tony; Rosebrock, Adam; Gingras, Anne-Claude; Fillingham, Jeffrey; Andrews, Brenda

2014-01-01

DNA replication occurs during the synthetic (S) phase of the eukaryotic cell cycle and features a dramatic induction of histone gene expression for concomitant chromatin assembly. Ectopic production of core histones outside of S phase is toxic, underscoring the critical importance of regulatory pathways that ensure proper expression of histone genes. Several regulators of histone gene expression in the budding yeast Saccharomyces cerevisiae are known, yet the key oscillator responsible for restricting gene expression to S phase has remained elusive. Here, we show that suppressor of Ty (Spt)10, a putative histone acetyltransferase, and its binding partner Spt21 are key determinants of S-phase–specific histone gene expression. We show that Spt21 abundance is restricted to S phase in part by anaphase promoting complex Cdc20-homologue 1 (APCCdh1) and that it is recruited to histone gene promoters in S phase by Spt10. There, Spt21-Spt10 enables the recruitment of a cascade of regulators, including histone chaperones and the histone-acetyltransferase general control nonderepressible (Gcn) 5, which we hypothesize lead to histone acetylation and consequent transcription activation. PMID:25228766

Correlation of skin test results and specific immunoglobulin E blood levels with nasal provocation testing for house-dust mite allergies.

Science.gov (United States)

Haxel, Boris R; Huppertz, Tilman; Boessert, Patrick; Bast, Florian; Fruth, Kai

2016-01-01

Allergen-specific immunotherapy for house-dust mite (HDM) allergies is associated with lower success rates when compared with similar treatments for other inhalant allergens, such as grass or birch. One reason might be the greater difficulty in diagnosing patients with assumed HDM allergies because symptoms occur perennially and may differ from those of a conventional allergic rhinitis. The aim of the study was to compare the different methods of diagnosis in patients with assumed HDM allergy. We performed a retrospective analysis of nasal provocation tests (NPT) from patients (n = 161) evaluated for Dermatophagoides pteronyssinus (n = 127) and Dermatophagoides farinae (n = 104) allergies, and compared the results with other allergen testing methods (skin-prick test [SPT], intracutaneous test, and allergen specific immunoglobulin E levels [sIgE] to detect sensitization). Receiver operating characteristic curves were used for the analyses and the areas under the curve were calculated. For D. pteronyssinus and D. farinae, 86 and 70 complete data files, respectively, were available. For both tested HDMs, the results of the receiver operating characteristic curves showed a significant correlation for SPT and sIgE, with the results of the NPT (area under the curve, 0.742 to 0.763) but not for the intracutaneous test. In patients with a positive SPT (≥3 mm), an allergy was confirmed by the NPT in 69% of cases for D. pteronyssinus and 71% for D. farinae. A positive sIgE result (ImmunoCAP class of ≥2) was verified by the NPT in 69% of cases (D. pteronyssinus) and 70% (D. farinae). The predictability value for a positive NPT result is best for SPT and sIgE. Nevertheless, even if the results of both test systems are combined, the positive predictive value that was achieved was only 0.77 for D. pteronyssinus and 0.69 for D. farinae. Therefore, in patients eligible for immunotherapy for HDM, an NPT should be performed before the start of the therapy to verify a clinically

Moessbauer studies of the structural phase transitions in RbFeF4

International Nuclear Information System (INIS)

Baumeler, Hp.; Keller, H.; Kuendig, W.; Savic, I.M.; Wanklyn, B.M.

1984-01-01

RbFeF 4 exhibits two structural phase transitions (SPT), namely a first-order transition at 381 K and a second-order transition at 417 K. A detailed 57 Fe Moessbauer investigation of these SPT is presented. At pronounced discontinuities in the quadrupole splitting and the recoil-free fraction are observed, whereas at 417 K both quantities vary continuously with temperature. Both SPT are also seen in the area ratio of the single crystal quadrupole lines which reflects the tilting of the FeF 6 octahedra with respect to the c-axis. However, no noticeable indication of the SPT is found in the center shift. (Auth.)

Moessbauer studies of the structural phase transitions in RbFeF/sub 4/

Energy Technology Data Exchange (ETDEWEB)

Baumeler, Hp.; Keller, H.; Kuendig, W.; Savic, I.M.; Wanklyn, B.M.

1984-03-20

RbFeF/sub 4/ exhibits two structural phase transitions (SPT), namely a first-order transition at 381 K and a second-order transition at 417 K. A detailed /sup 57/Fe Moessbauer investigation of these SPT is presented. At pronounced discontinuities in the quadrupole splitting and the recoil-free fraction are observed, whereas at 417 K both quantities vary continuously with temperature. Both SPT are also seen in the area ratio of the single crystal quadrupole lines which reflects the tilting of the FeF/sub 6/ octahedra with respect to the c-axis. However, no noticeable indication of the SPT is found in the center shift.

Molecular Characterization of Foot-and-Mouth Disease Viruses Collected in Tanzania Between 1967 and 2009.

Science.gov (United States)

Kasanga, C J; Wadsworth, J; Mpelumbe-Ngeleja, C A R; Sallu, R; Kivaria, F; Wambura, P N; Yongolo, M G S; Rweyemamu, M M; Knowles, N J; King, D P

2015-10-01

This paper describes the molecular characterization of foot-and-mouth disease viruses (FMDV) recovered from outbreaks in Tanzania that occurred between 1967 and 2009. A total of 44 FMDV isolates, containing representatives of serotypes O, A, SAT 1 and SAT 2 from 13 regions of Tanzania, were selected from the FAO World Reference Laboratory for FMD (WRLFMD) virus collection. VP1 nucleotide sequences were determined for RT-PCR amplicons, and phylogenetic reconstructions were determined by maximum likelihood and neighbour-joining methods. These analyses showed that Tanzanian type O viruses fell into the EAST AFRICA 2 (EA-2) topotype, type A viruses fell into the AFRICA topotype (genotype I), type SAT 1 viruses into topotype I and type SAT 2 viruses into topotype IV. Taken together, these findings reveal that serotypes O, A, SAT 1 and SAT 2 that caused FMD outbreaks in Tanzania were genetically related to lineages and topotypes occurring in the East African region. The close genetic relationship of viruses in Tanzania to those from other countries suggests that animal movements can contribute to virus dispersal in sub-Saharan Africa. This is the first molecular description of viruses circulating in Tanzania and highlights the need for further sampling of representative viruses from the region so as to elucidate the complex epidemiology of FMD in Tanzania and sub-Saharan Africa. © 2014 The Authors. Transboundary and Emerging Diseases Published by Blackwell Verlag GmbH.

The state of the warm and cold gas in the extreme starburst at the core of the Phoenix galaxy cluster (SPT-CLJ2344-4243)

International Nuclear Information System (INIS)

McDonald, Michael; Bautz, Marshall W.; Swinbank, Mark; Edge, Alastair C.; Hogan, Michael T.; Wilner, David J.; Bayliss, Matthew B.; Veilleux, Sylvain; Benson, Bradford A.; Marrone, Daniel P.; McNamara, Brian R.; Wei, Lisa H.

2014-01-01

We present new optical integral field spectroscopy (Gemini South) and submillimeter spectroscopy (Submillimeter Array) of the central galaxy in the Phoenix cluster (SPT-CLJ2344-4243). This cluster was previously reported to have a massive starburst (∼800 M ☉ yr –1 ) in the central, brightest cluster galaxy, most likely fueled by the rapidly cooling intracluster medium. These new data reveal a complex emission-line nebula, extending for >30 kpc from the central galaxy, detected at [O II]λλ3726, 3729, [O III]λλ4959, 5007, Hβ, Hγ, Hδ, [Ne III]λ3869, and He II λ4686. The total Hα luminosity, assuming Hα/Hβ = 2.85, is L Hα = 7.6 ± 0.4 ×10 43 erg s –1 , making this the most luminous emission-line nebula detected in the center of a cool core cluster. Overall, the relative fluxes of the low-ionization lines (e.g., [O II], Hβ) to the UV continuum are consistent with photoionization by young stars. In both the center of the galaxy and in a newly discovered highly ionized plume to the north of the galaxy, the ionization ratios are consistent with both shocks and active galactic nucleus (AGN) photoionization. We speculate that this extended plume may be a galactic wind, driven and partially photoionized by both the starburst and central AGN. Throughout the cluster we measure elevated high-ionization line ratios (e.g., He II/Hβ, [O III]/Hβ), coupled with an overall high-velocity width (FWHM ≳ 500 km s –1 ), suggesting that shocks are likely important throughout the interstellar medium of the central galaxy. These shocks are most likely driven by a combination of stellar winds from massive young stars, core-collapse supernovae, and the central AGN. In addition to the warm, ionized gas, we detect a substantial amount of cold, molecular gas via the CO(3-2) transition, coincident in position with the galaxy center. We infer a molecular gas mass of M H 2 = 2.2 ± 0.6 × 10 10 M ☉ , which implies that the starburst will consume its fuel in ∼30 Myr if

A Case Study On Pile Relaxation In Dilative Silts

Science.gov (United States)

2011-12-20

2 Table 2-1 Correlation of Uncorrected SPT N -Value with Total Unit Weight and Friction Angle (Kulhawy and Mayne, 1990...Effective internal friction angle. N = Uncorrected SPT blow count. σ’v = Effective vertical stress. cn = Overburden correction factor...shear strength of the soil. The unit weight of a soil can be determined from correlations to SPT N values, as shown in Table 2.1. 10

Untitled

African Journals Online (AJOL)

BA opplied 6 doys of ter onthesis a. Taking the terminal raceme as a whole, the treatments did not show significant differences with respect to the total number of flowers produced and those flowers that developed into pods. Figure 1 shows the daily pattern of pod abscission as influenced by BA applied at different times.

Dando vida me doy vida: Una experiencia de investigación acción con familias

OpenAIRE

Arce-Chavarría, Eilyn

2015-01-01

Este artículo es el resultado de una investigación acción participativa, expresa mi compartir con nueve de catorce familias del estudiantado que asiste al centro de educación especial para el cual trabajo, y cursan los niveles de intervención temprana (0 a 3 años de edad), preescolar (3 a 6 años y 6 meses de edad) y primer ciclo (6 años y 6 meses a 9 años de edad). Seis de las familias participantes estaban compuestas por papá y mamá y las otras tres solo por la madre. Incorpora seis tardes d...

Role of nasal challenge and local eosinophilia in indirect exposure to cat in allergic rhinitis patients.

Science.gov (United States)

Al Ahmad, M; Arifhodzic, N; Nurkic, J; Jusufovic, E; Hanoun, A L; Rodriguez, T

2018-01-17

Introduction. Sensitization to cat allergens is common worldwide. Currently, there is a trend towards costly and often unavailable diagnostic analysis. Objectives. The aim is to assess the reliability of skin prick test (SPT) and serum specific IgE (ssIgE) to cat sensitization, by performing nasal challenge test (NCT) in a community with low cat ownership but common presence of stray cats. Patients and methods. Forty-one pa-tients with perennial allergic rhinitis (AR) who were mono or polysensitized (including cat) were included. We had 31 cat non-owners and 10 present cat owners. SPT (> 5 mm / diameter), ssIgE (≥ 0.70 IU/ml), nasal smear for eosinophil (Eo) and NCT were compared between groups. Outcomes included nasal challenge score, nasal Eo positivity, peak inspiratory and expiratory flow (PIF and PEF) 2 and 8 hours after the NCT, and were compared to baseline. Results. Baseline SPT wheal size and ssIgE level were similar in both groups. NCT positivity was more frequent in cat owners. The strongest nasal reaction was on the top concentration in both groups. Nasal Eo positivity in cat owners was higher before and 2 hours after NCT, but similar to non-owners at last measurement. NCT positive cat non-owners had bigger SPT wheal size than NCT negative non-owners, but smaller than NCT positive cat owners. In contrast to PEF, a significant fall in PIF was noticed in both groups. Mono and polysensitised patients showed similar NCT positivity. Conclusion. Stray cats may pose a relevant risk of developing perennial AR. Regardless of cat ownership status, SPT and ssIgE should be the first diagnostic tool. Nasal Eo and NCT seem to be good diagnostic tools in cat non-owners if diagnosis is elusive.

Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease

Science.gov (United States)

Grimm, Marcus O. W.; Grösgen, Sven; Rothhaar, Tatjana L.; Burg, Verena K.; Hundsdörfer, Benjamin; Haupenthal, Viola J.; Friess, Petra; Müller, Ulrike; Fassbender, Klaus; Riemenschneider, Matthias; Grimm, Heike S.; Hartmann, Tobias

2011-01-01

Lipids play an important role as risk or protective factors in Alzheimer's disease (AD), a disease biochemically characterized by the accumulation of amyloid beta peptides (Aβ), released by proteolytic processing of the amyloid precursor protein (APP). Changes in sphingolipid metabolism have been associated to the development of AD. The key enzyme in sphingolipid de novo synthesis is serine-palmitoyl-CoA transferase (SPT). In the present study we identified a new physiological function of APP in sphingolipid synthesis. The APP intracellular domain (AICD) was found to decrease the expression of the SPT subunit SPTLC2, the catalytic subunit of the SPT heterodimer, resulting in that decreased SPT activity. AICD function was dependent on Fe65 and SPTLC2 levels are increased in APP knock-in mice missing a functional AICD domain. SPTLC2 levels are also increased in familial and sporadic AD postmortem brains, suggesting that SPT is involved in AD pathology. PMID:21660213

Robust model-based analysis of single-particle tracking experiments with Spot-On

Science.gov (United States)

Grimm, Jonathan B; Lavis, Luke D

2018-01-01

Single-particle tracking (SPT) has become an important method to bridge biochemistry and cell biology since it allows direct observation of protein binding and diffusion dynamics in live cells. However, accurately inferring information from SPT studies is challenging due to biases in both data analysis and experimental design. To address analysis bias, we introduce ‘Spot-On’, an intuitive web-interface. Spot-On implements a kinetic modeling framework that accounts for known biases, including molecules moving out-of-focus, and robustly infers diffusion constants and subpopulations from pooled single-molecule trajectories. To minimize inherent experimental biases, we implement and validate stroboscopic photo-activation SPT (spaSPT), which minimizes motion-blur bias and tracking errors. We validate Spot-On using experimentally realistic simulations and show that Spot-On outperforms other methods. We then apply Spot-On to spaSPT data from live mammalian cells spanning a wide range of nuclear dynamics and demonstrate that Spot-On consistently and robustly infers subpopulation fractions and diffusion constants. PMID:29300163

Perineal injuries and birth positions among 2992 women with a low risk pregnancy who opted for a homebirth

DEFF Research Database (Denmark)

Edqvist, Malin; Blix, Ellen; Hegaard, Hanne K

2016-01-01

at home and to compare the prevalence of perineal injuries, SPT and episiotomy in different birth positions in four Nordic countries. METHODS: A population-based prospective cohort study of planned home births in four Nordic countries. To assess medical outcomes a questionnaire completed after birth...... by the attending midwife was used. Descriptive statistics, bivariate analysis and logistic regression were used to analyze the data. RESULTS: Two thousand nine hundred ninety-two women with planned home births, who birthed spontaneously at home or after transfer to hospital, between 2008 and 2013 were included.......26-1.79). Flexible sacrum positions were associated with fewer episiotomies (OR 0.20; CI 95 % 0.10-0.54). CONCLUSION: A low prevalence of SPT and episiotomy was found among women opting for a home birth in four Nordic countries. Women used a variety of birth positions and a majority gave birth in flexible sacrum...

Classics in physical geography revisited. Hewlett, J.D. and Hibbert, A.R. 1967: Factors affecting the response of small watersheds to precipitation in humid areas. In Sopper, W.E. and Lull, H.W., editors, Forest hydrology, New York: Pergamon Press, 275-90.

Science.gov (United States)

Jeffrey J. McDonnell

2009-01-01

Hewlett and Hibbert’s (1967) ‘Factors affecting the response of small watersheds to precipitation in humid areas’ (hereafter referred to as ‘Factors’) is one of the most important papers published in the field of catchment hydrology.

Skin prick test in patients with chronic allergic skin disorders

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Pooja Bains

2015-01-01

Full Text Available Background: Chronic allergic skin disorders are the inflammatory and proliferative conditions in which both genetic and environmental factors play important roles. Chronic idiopathic urticaria (CIU and atopic dermatitis (AD are among the most common chronic allergic skin disorders. These can be provoked by various food and aeroallergens. Skin prick tests (SPTs represent the cheapest and most effective method to diagnose type I hypersensitivity. Positive skin tests with a history suggestive of clinical sensitivity strongly incriminate the allergen as a contributor to the disease process. Aim s and Objectives: To determine the incidence of positive SPT in patients with chronic allergic skin disorders and to identify the various allergens implicated in positive SPT. Methods: Fifty patients of chronic allergic disorders were recruited in this study. They were evaluated by SPT with both food and aeroallergens. Results: In our study, SPT positivity in patients of CIU was 63.41% and in AD was 77.78%. Out of the 41 patients of CIU, the most common allergen groups showing SPT positivity were dust and pollen, each comprising 26.83% patients. SPT reaction was positive with food items (21.6%, insects (17.07%, fungus (12.20%, and Dermatophagoides farinae, that is, house dust mite (HDM (7.32%. The allergen which showed maximum positivity was grain dust wheat (19.51%. Among nine patients of AD, maximum SPT positivity was seen with Dermatophagoides farinae, pollen Amaranthus spinosus, grain dust wheat, and cotton mill dust; each comprising 22.22% of patients. Conclusion: Our study showed that a significant number of patients of CIU and AD showed sensitivity to dust, pollen, insects, Dermatophagoides farinae, and fungi on SPT. Thus, it is an important tool in the diagnosis of CIU and AD.

Actigraphy combined with EEG compared to polysomnography in sleep apnea patients

International Nuclear Information System (INIS)

Fietze, Ingo; Penzel, Thomas; Partinen, Markku; Sauter, Jochen; Küchler, Gert; Suvoro, Alexander; Hein, Holger

2015-01-01

An actigraph extended with electroencephalography (EEG), electroocculography (EOG) and electromyography (EMG) was compared to polysomnography in two studies on patients suffering from sleep disordered breathing. Study A with 30 subjects used a single lead EEG, and study B with 20 subjects used EOG and EMG in addition. Sleep was scored according to Rechtschaffen and Kales rules. Total sleep time (TST), sleep period time (SPT), sleep efficiency (SE), sustained sleep efficiency (SSE), sleep-onset latency (SL), and sleep stages were compared. For study A an epoch-by-epoch comparison of sleep stages revealed an overall agreement of 74.2%. Correlations were high for SE (0.98, p < 0.001), SSE (0.98, p < 0.001), TST (0.99, p < 0.001), SPT (0.99, p < 0.001), and SL (0.98, p < 0.001). Regarding the sleep stages, correlations were high for rapid eye movement (REM) (0.83, p < 0.001), light-sleep (0.78, p < 0.001), and deep sleep (0.73, p < 0.001). For study B, results of an epoch-by-epoch comparison of sleep stages showed an overall agreement of 75.5%. Correlations were high for SE (0.98, p < 0.001), SSE (0.98, p < 0.001), TST (0.87, p < 0.001), SL (0.98, p < 0.001), SPT (0.94, p < 0.001), and for rapid eye movement (REM) (0.91, p < 0.001), light-sleep (0.74, p < 0.001), and deep sleep (0.89, p < 0.001). In summary the study revealed high agreement between polysomnography and single lead EEG in sleep apnea patients. Deviations for REM were slightly higher for the single lead EEG compared to single lead EEG plus EOG/EMG. Both simplified systems proved to be reliable for comfortable out-patient sleep recording. (paper)

Empirical Comparison of Two Psychological Therapies: Self Psychology and Cognitive Orientation in the Treatment of Anorexia and Bulimia

Science.gov (United States)

Bachar, Eytan; Latzer, Yael; Kreitler, Shulamit; Berry, Elliot M.

1999-01-01

The authors investigated the applicability of self psychological treatment (SPT) and cognitive orientation treatment (COT) to the treatment of anorexia and bulimia. Thirty-three patients participated in this study. The bulimic patients (n = 25) were randomly assigned either to SPT, COT, or control/nutritional counseling only (C/NC). The anorexic patients (n = 8) were randomly assigned to either SPT or COT. Patients were administered a battery of outcome measures assessing eating disorders symptomatology, attitudes toward food, self structure, and general psychiatric symptoms. After SPT, significant improvement was observed. After COT, slight but nonsignificant improvement was observed. After C/NC, almost no changes could be detected.(The Journal of Psychotherapy Practice and Research 1999; 8:115–128) PMID:10079459

Gas-breakdown effects associated with the self-pinched transport of intense light-ion beams

International Nuclear Information System (INIS)

Ottinger, P.F.; Olson, C.L.; Welch, D.R.; Oliver, B.V.

1997-01-01

Self-pinched transport (SPT) of intense light-ion beams is being considered for delivering energy to a high-gain, high-yield inertial confinement fusion target. Proton beam SPT experiments are underway on the Gamble II generators at the Naval Research Laboratory. The physics of SPT in low-pressure gas is being analyzed with analytic theory and numerical simulations. A 1-D theory estimates the net current fraction necessary for stable transport as a function of gas density for a given beam profile. SPT simulations using the 3-D hybrid particle-in-cell (PIC) code IPROP determine the beam profile. Important to both theory and simulations is the inclusion of gas-breakdown physics. A comparison between the theory and the self-consistent simulations using IPROP is made. Additional SPT simulations have been carried out using the 2-D hybrid PIC code SOLENZ which assumes a pre-ionized plasma. This simulation model enables the investigation of long time scale beam propagation issues. A comparison between IPROP and SOLENZ will be presented. SOLENZ simulations with the Gamble I beam parameters demonstrate SPT but point to the need to study the injection conditions to improve beam confinement. Simulations examining beam-to-wall distance and injection conditions will be presented

Lupin sensitization and clinical allergy in food allergic children in Norway.

Science.gov (United States)

Lindvik, Helene; Holden, Lise; Løvik, Martinus; Cvancarova, Milada; Halvorsen, Ragnhild

2008-01-01

The aim of the present pilot study was to investigate to what extent children in Norway sensitized to lupin had clinical lupin allergy, and to compare sensitization to lupin with sensitization to other legumes. Thirty-five children with food allergy referred to a national referral hospital were evaluated with skin prick test (SPT) and analysis of serum-specific IgE to lupin, peanut, pea and soy. The children with positive SPTs to lupin were offered oral food challenges with lupin flour. Fifteen children (43%) had positive SPT and 17 children (49%) had serum-specific IgE to lupin. Ten SPT-positive children underwent oral food challenges and one experienced an allergic reaction to lupin flour. This child was one of six challenged children with IgE antibodies to peanut >15 kU(A)/L. There was a strong relationship between positive SPT to lupin flour and positive SPT to soy and between positive SPT to lupin and specific IgE to soy, pea and peanut. Children with sensitization to lupin are not likely to have a clinical lupin allergy. Avoidance of lupin on the basis of lupin sensitization or peanut allergy would lead to unnecessarily strict diets. Food challenge is currently necessary to diagnose lupin allergy.

La tuberculosis de “Doc” Holliday en el cine. La hora de las pistolas/ Hour Of The Gun (1967 y Duelo a muerte en O.K. Corral/ “Doc” (1971

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José Elías García Sánchez

2008-10-01

Full Text Available La hora de las pistolas (1967 de John Sturges comienza en el famoso duelo en el O.K. Corral mientras que Duelo a muerte en O.K. Corral (1971 de Frank Perry, como sus predecesoras Pasión de los fuertes (1946 y Duelo de titanes (1957 termina en él. Ambas películas muestran la tuberculosis pulmonar de “Doc” Holliday. La primera incide especialmente en sus últimos días en el sanatorio antituberculoso de Glenwood Springs y la segunda, en la que es el protagonista, con sus intensos ataques de tos.

Ballistic Missile Defense System (BMDS)

Science.gov (United States)

2015-12-01

Deliveries: 1 JBMD BLK 04 Computer Program, Peripherals, and SM-3 BLK IA Missiles. Japan 8/13/2004 0 21.3 FMS Case JA-P-BGQ: Proof of Principle (PoP...Estimate Econ Qty Sch Eng Est Oth Spt Total 0.000 -- -- -- -- -- -- -- -- 0.000 An APUC Unit Cost History is not available, since no Initial APUC Estimate

Distributional changes in the western Burrowing Owl (Athene cunicularia hypugaea) in North America from 1967 to 2008

Science.gov (United States)

Macias-Duarte, Alberto; Conway, Courtney J.

2015-01-01

The quantification of shifts in bird distributions in response to climate change provides an opportunity to gain a deeper understanding of the processes that influence species persistence. We used data from the North American Breeding Bird Survey (BBS) to document changes in the distributional limits of the western Burrowing Owl (Athene cunicularia hypugaea) from 1967 to 2008. We used logistic regression to model presence probability (p) as a function of longitude, latitude, and year. We modeled a linear trend in logit(p) through time with slope and intercept modeled as a double Fourier series of longitude and latitude. We found that the western Burrowing Owl has experienced an intriguing southward shift in the northern half of its breeding range, contrary to what is predicted by most species niche models and what has been observed for many other species in North America. The breeding range of the Burrowing Owl has been shrinking near its northern, western, and eastern edges. Our model detected the population declines that were observed in California and eastern Washington, in locations where maps based on route-specific estimating equations had predicted significant population increases. We suggest that the northern boundary of the breeding distribution of the western Burrowing Owl has contracted southward and the southern boundary of the species' breeding distribution has expanded southward into areas of northern Mexico that were formerly used only by wintering migrants.

A comparison of single particle tracking and temporal image correlation spectroscopy for quantitative analysis of endosome motility

DEFF Research Database (Denmark)

Lund, F. W.; Wustner, D.

2013-01-01

Single particle tracking (SPT) is becoming a standard method to extract transport parameters from time-lapse image sequences of fluorescent vesicles in living cells. Another method to obtain these data is temporal image correlation spectroscopy (TICS), but this method is less often used for measu......Single particle tracking (SPT) is becoming a standard method to extract transport parameters from time-lapse image sequences of fluorescent vesicles in living cells. Another method to obtain these data is temporal image correlation spectroscopy (TICS), but this method is less often used...... for measurement of intracellular vesicle transport. Here, we present an extensive comparison of SPT and TICS. First we examine the effect of photobleaching, shading and noise on SPT and TICS analysis using simulated image sequences. To this end, we developed a simple photophysical model, which relates spatially...... varying illumination intensity to the bleaching propensity and fluorescence intensity of the moving particles. We found that neither SPT nor TICS are affected by photobleaching per se, but the transport parameters obtained by both methods are sensitive to the signal-to-noise ratio. In addition, the number...

Entre a política e o prazer: ditadura, arte e boêmia através do filme Garota de Ipanema (Leon Hirszman, 1967 = Between politics and pleasure: dictatorship, art and bohemia throughout Leon Hirszman’s Garota de Ipanema (1967 = Entre la política y el placer: dictadura, arte y bohemia a través del film Garota de Ipanema (Leon Hirszman, 1967

Directory of Open Access Journals (Sweden)

Pinto, Carlos Eduardo Pinto de

2017-01-01

Full Text Available O artigo aborda, através da análise do filme Garota de Ipanema (Leon Hirszman, 1967 e de seu circuito social, as tensões entre política e prazer no cotidiano do Rio de Janeiro durante a ditadura militar. A releitura de uma canção da Bossa Nova através de um filme que pretendia acompanhar o cotidiano de uma menina de classe média em Ipanema é esperada como um rompimento com os pressupostos do cinema político seguidos até então por seu diretor, um dos expoentes do Cinema Novo brasileiro. Afinal, tanto a Bossa quanto Ipanema eram consideradas metonímias de uma boêmia despolitizada que não se conectava, aparentemente, com a proposta de intervenção da arte na sociedade, seguida pelos cinemanovistas. Ironicamente, o filme decepcionou a crítica, justamente por não ser um bom entretenimento, se propondo a compreender a inserção da protagonista no mundo, inclusive sua relação com a política sob uma ditadura. Desse modo, a análise possibilita pensar as conexões entre ditadura, arte e boêmia no filme e através dele

Cosmological data and indications for new physics

Energy Technology Data Exchange (ETDEWEB)

Benetti, Micol [Physics Department and ICRA, Università di Roma ' ' La Sapienza' ' , Ple. Aldo Moro 2, 00185, Rome (Italy); Gerbino, Martina; Melchiorri, Alessandro; Pagano, Luca [Physics Department and INFN, Università di Roma ' ' La Sapienza' ' , Ple Aldo Moro 2, 00185, Rome (Italy); Kinney, William H. [Department of Physics, University at Buffalo, the State University of New York, Buffalo, NY 14260-1500 (United States); Kolb, Edward W. [Department of Astronomy and Astrophysics, Enrico Fermi Institute, and Kavli Institute for Cosmological Physics, University of Chicago, Chicago, Illinois 60637-1433 (United States); Lattanzi, Massimiliano [Dipartimento di Fisica e Science della Terra, Università di Ferrara and INFN, sezione di Ferrara, Polo Scientifico e Tecnologico - Edificio C Via Saragat, 1, I-44122 Ferrara Italy (Italy); Riotto, Antonio, E-mail: micol.benetti@roma1.infn.it, E-mail: martina.gerbino@roma1.infn.it, E-mail: whkinney@buffalo.edu, E-mail: Rocky.Kolb@uchicago.edu, E-mail: lattanzi@fe.infn.it, E-mail: alessandro.melchiorri@roma1.infn.it, E-mail: luca.pagano@roma1.infn.it, E-mail: antonio.riotto@unige.ch [Department of Theoretical Physics and Center for Astroparticle Physics (CAP) 24 quai E. Ansermet, CH-1211 Geneva 4 (Switzerland)

2013-10-01

Data from the Atacama Cosmology Telescope (ACT) and the South Pole Telescope (SPT), combined with the nine-year data release from the WMAP satellite, provide very precise measurements of the cosmic microwave background (CMB) angular anisotropies down to very small angular scales. Augmented with measurements from Baryonic Acoustic Oscillations surveys and determinations of the Hubble constant, we investigate whether there are indications for new physics beyond a Harrison-Zel'dovich model for primordial perturbations and the standard number of relativistic degrees of freedom at primordial recombination. All combinations of datasets point to physics beyond the minimal Harrison-Zel'dovich model in the form of either a scalar spectral index different from unity or additional relativistic degrees of freedom at recombination (e.g., additional light neutrinos). Beyond that, the extended datasets including either ACT or SPT provide very different indications: while the extended-ACT (eACT) dataset is perfectly consistent with the predictions of standard slow-roll inflation, the extended-SPT (eSPT) dataset prefers a non-power-law scalar spectral index with a very large variation with scale of the spectral index. Both eACT and eSPT favor additional light degrees of freedom on top of the Harrison-Zel'dovich model. eACT is consistent with zero neutrino masses, while eSPT favors nonzero neutrino masses at more than 95% confidence.

The Transfer of Cognitive Speed of Processing Training to Older Adults’ Driving Mobility Across 5 Years

Science.gov (United States)

Edwards, Jerri D.; O’Connor, Melissa L.; Ball, Karlene K.; Wadley, Virginia G.; Vance, David E.

2016-01-01

Objectives. Multilevel models assessed the effects of cognitive speed of processing training (SPT) on older adults’ self-reported driving using intention-to-treat (ITT, randomization to training or control conditions) and dosage (treatment-received via number of training sessions) analyses across 5 years. Method. Participants randomized to SPT (n = 598) were compared with those randomized to either the no-contact control (n = 598) or memory training, which served as an active control (n = 610). Driving mobility (frequency, exposure, and space) was assessed over time. Results. No significant effects were found within the ITT analyses. However, number of SPT sessions did affect driving mobility outcomes. In the full sample (N = 1,806), higher SPT doses were associated with maintained driving frequency as compared with both control groups, but no effects were found for driving exposure or space. Subsample analyses (n = 315) revealed that persons at-risk for mobility declines (i.e., poor initial processing speed) who received additional booster SPT sessions reported greater maintenance of both driving frequency and exposure over time as compared with the no-contact and active control groups. Discussion. These results and prior research indicate that cognitive SPT transfers to prolonged driving mobility among older adults. Future research should investigate the mechanisms behind transfer effects to real-world activities, such as driving. PMID:25878053

Self-pinched transport of intense ion beams

International Nuclear Information System (INIS)

Ottinger, P.F.; Neri, J.M.; Stephanakis, S.J.

1999-01-01

Electron beams with substantial net currents have been routinely propagated in the self-pinched mode for the past two decades. However, as the physics of gas breakdown and beam neutralization is different for ion beams, previous predictions indicated insufficient net current for pinching so that ion beam self-pinched transport (SPT) was assumed impossible. Nevertheless, recent numerical simulations using the IPROP code have suggested that ion SPT is possible. These results have prompted initial experiments to investigate SPT of ion beams. A 100-kA, 1.2-MeV, 3-cm-radius proton beam, generated on the Gamble II pulsed-power accelerator at NRL, has been injected into helium in the 30- to 250-mTorr regime to study this phenomenon. Evidence of self-pinched ion beam transport was observed in the 35- to 80-mTorr SPT pressure window predicted by IPROP. Measured signals from a time- and space-resolved scattered proton diagnostic and a time-integrated Li(Cu) nuclear activation diagnostic, both of which measure protons striking a 10-cm diameter target 50 cm into the transport region, are significantly larger in this pressure window than expected for ballistic transport. These results are consistent with significant self-magnetic fields and self-pinching of the ion beam. On the other hand, time-integrated signals from these same two diagnostics are consistent with ballistic transport at pressures above and below the SPT window. Interferometric electron line-density measurements, acquired during beam injection into the helium gas, show insignificant ionization below 35 mTorr, a rapidly rising ionization fraction with pressure in the SPT window, and a plateau in ionization fraction at about 2% for pressures above 80 mTorr. These and other results are consistent with the physical picture for SPT. IPROP simulations, which closely model the Gamble II experimental conditions, produce results that are in qualitative agreement with the experimental results. The advantages of SPT for

Determination of blood leukocyte concentration with constant volume acquisition on a flow cytometer is comparable to individualized single platform testing with beads as internal reference standard

DEFF Research Database (Denmark)

Hansen, Susan; Dahl, Ronald; Hoffmann, Hans Jürgen

2008-01-01

at a high rate has a median of 163 microl (IQR 156-170) with TruCount tubes. Leukocyte concentrations of 26 healthy volunteers were measured twice on up to four occasions with a Bürker-Türk chamber, by single platform technology (SPT) with TruCount tubes and on the same data set using CVA. Total leukocyte...... concentrations determined by CVA correlated better with measurements in a Bürker-Türk (BT) chamber than with SPT. Concentrations determined with CVA were 1.86% higher than with BT whereas SPT data were 5.35% higher than BT (p...LeukoGating can be established using microscopy as a reference, and is comparable to BT chamber and SPT determination. Leukocyte concentrations can be measured with CVA on flow cytometers in research and clinical settings....

Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study

Science.gov (United States)

2010-01-01

Background Susceptibility to atopy originates from effects of the environment on genes. Birth order has been identified as a risk factor for atopy and evidence for some candidate genes has been accumulated; however no study has yet assessed a birth order-gene interaction. Objective To investigate the interaction of IL13 polymorphisms with birth order on allergic sensitization at ages 4, 10 and 18 years. Methods Mother-infant dyads were recruited antenatally and followed prospectively to age 18 years. Questionnaire data (at birth, age 4, 10, 18); skin prick test (SPT) at ages 4, 10, 18; total serum IgE and specific inhalant screen at age 10; and genotyping for IL13 were collected. Three SNPs were selected from IL13: rs20541 (exon 4, nonsynonymous SNP), rs1800925 (promoter region) and rs2066960 (intron 1). Analysis included multivariable log-linear regression analyses using repeated measurements to estimate prevalence ratios (PRs). Results Of the 1456 participants, birth order information was available for 83.2% (1212/1456); SPT was performed on 67.4% at age 4, 71.2% at age 10 and 58.0% at age 18. The prevalence of atopy (sensitization to one or more food or aeroallergens) increased from 19.7% at age 4, to 26.7% at 10 and 41.1% at age 18. Repeated measurement analysis indicated interaction between rs20541 and birth order on SPT. The stratified analyses demonstrated that the effect of IL13 on SPT was restricted only to first-born children (p = 0.007; adjusted PR = 1.35; 95%CI = 1.09, 1.69). Similar findings were noted for firstborns regarding elevated total serum IgE at age 10 (p = 0.007; PR = 1.73; 1.16, 2.57) and specific inhalant screen (p = 0.034; PR = 1.48; 1.03, 2.13). Conclusions This is the first study to show an interaction between birth order and IL13 polymorphisms on allergic sensitization. Future functional genetic research need to determine whether or not birth order is related to altered expression and methylation of the IL13 gene. PMID:20403202

Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study

Directory of Open Access Journals (Sweden)

Ogbuanu Ikechukwu U

2010-04-01

Full Text Available Abstract Background Susceptibility to atopy originates from effects of the environment on genes. Birth order has been identified as a risk factor for atopy and evidence for some candidate genes has been accumulated; however no study has yet assessed a birth order-gene interaction. Objective To investigate the interaction of IL13 polymorphisms with birth order on allergic sensitization at ages 4, 10 and 18 years. Methods Mother-infant dyads were recruited antenatally and followed prospectively to age 18 years. Questionnaire data (at birth, age 4, 10, 18; skin prick test (SPT at ages 4, 10, 18; total serum IgE and specific inhalant screen at age 10; and genotyping for IL13 were collected. Three SNPs were selected from IL13: rs20541 (exon 4, nonsynonymous SNP, rs1800925 (promoter region and rs2066960 (intron 1. Analysis included multivariable log-linear regression analyses using repeated measurements to estimate prevalence ratios (PRs. Results Of the 1456 participants, birth order information was available for 83.2% (1212/1456; SPT was performed on 67.4% at age 4, 71.2% at age 10 and 58.0% at age 18. The prevalence of atopy (sensitization to one or more food or aeroallergens increased from 19.7% at age 4, to 26.7% at 10 and 41.1% at age 18. Repeated measurement analysis indicated interaction between rs20541 and birth order on SPT. The stratified analyses demonstrated that the effect of IL13 on SPT was restricted only to first-born children (p = 0.007; adjusted PR = 1.35; 95%CI = 1.09, 1.69. Similar findings were noted for firstborns regarding elevated total serum IgE at age 10 (p = 0.007; PR = 1.73; 1.16, 2.57 and specific inhalant screen (p = 0.034; PR = 1.48; 1.03, 2.13. Conclusions This is the first study to show an interaction between birth order and IL13 polymorphisms on allergic sensitization. Future functional genetic research need to determine whether or not birth order is related to altered expression and methylation of the IL13 gene.

Trans advanced surface laser ablation (TransPRK) outcomes using SmartPulseTechnology.

Science.gov (United States)

Aslanides, Ioannis M; Kymionis, George D

2017-02-01

To evaluate early visual rehabilitation, post-operative pain, epithelial healing and haze after transepithelial photorefractive keratectomy (TransPRK) using the SmartPulseTechnology (SPT) of Schwind Amaris (Schwind eye-tech-solutions GmbH, Kleinostheim, Germany). This was a retrospective comparative evaluation of a cohort of myopic patients undergoing TransPRK with SPT (group 1), with one matched control group that underwent conventional TransPRK (group 2). All cases had a 6-month post-operative follow-up including visual acuity and slit-lamp examination. Subjective evaluation of pain was recorded post-operatively. 49 eyes of 25 patients in group 1 and 40 eyes of 20 patients in group 2 were enrolled. The patients' visual rehabilitation was significantly faster in group 1, one day and one week post-operatively (P0.05). TransPRK using SPT provides promising results in the early post-operative period. Visual rehabilitation, re-epithelialization and pain were faster in the early post-operative period in group 1 in comparison with group 2. Haze formation was not significantly different between the two groups; however, it was consistently less in group 1. Copyright © 2016 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

Contrasting cultural landscapes and spaces in Peter Weir’s film Picnic at Hanging Rock (1975, based on Joan Lindsay’s 1967 novel with the same title

Directory of Open Access Journals (Sweden)

Jytte Holmqvist

2013-10-01

Full Text Available The following essay explores the relationship between contrasting cultures and cultural spaces within a rural Australian, Victorian, context, with reference to the narrated cultural landscape in Joan Lindsay’s novel Picnic at Hanging Rock (1967 and in the film based on the novel, by Peter Weir (1975. In the analysis of the five first scenes of the film, the focus will be on the notion of scenic- and human- beauty that is at once arresting and foreboding, and the various contrasting and parallel spaces that characterise the structure of book and film. The article will draw from a number of additional secondary sources, including various cultural readings which offer alternative methodological approaches to the works analysed, and recorded 1970s interviews with the author and the filmmaker.

CHANGES IN THE STRUCTURE OF COAL AND STEEL INDUSTRIES UNDER THE ECSC (1952-1967: WAS WEST GERMANY KEPT “SMALL”?

Directory of Open Access Journals (Sweden)

Eline Poelmans

2012-01-01

Full Text Available In 1951, six European countries founded the European Coal and Steel Community (ECSC, which they hoped would be a first step towards more European integration and which they hoped would provide a common legal framework for their coal and steel industries. The main aim of the ECSC was to make sure that the German coal and steel industries would never again reach their prewar capacities, which according to many had played a part in the coming of World War II. Another important aim was to forestall any attempt of the USSR to conquer West Germany. This article constitutes a case study of the regional concentration of the coal and steel industries in the six ECSC countries, and it investigates whether the importance of certain coal and steel producing regions within the ECSC changed between 1952 and 1967. Furthermore, an analysis is conducted of how the concentration ratios of the ECSC's industries differed among the six countries, whether these differences changed over time, how this influenced the size and number of coal and steel firms and whether the ECSC succeeded in its initial aim of keeping West Germany small.

investigation of shallow foundation soil bearing capacity

African Journals Online (AJOL)

HOD

SITE USING PLAXIS 2D SOFTWARE AND EMPIRICAL FORMULATIONS ... development site using standard penetration test (SPT) data obtained from10 SPT ... The numerical analysis results using Plaxis 2D, a finite element code, shows the ...

Subunits of ADA-two-A-containing (ATAC) or Spt-Ada-Gcn5-acetyltrasferase (SAGA) Coactivator Complexes Enhance the Acetyltransferase Activity of GCN5.

Science.gov (United States)

Riss, Anne; Scheer, Elisabeth; Joint, Mathilde; Trowitzsch, Simon; Berger, Imre; Tora, László

2015-11-27

Histone acetyl transferases (HATs) play a crucial role in eukaryotes by regulating chromatin architecture and locus specific transcription. GCN5 (KAT2A) is a member of the GNAT (Gcn5-related N-acetyltransferase) family of HATs. In metazoans this enzyme is found in two functionally distinct coactivator complexes, SAGA (Spt Ada Gcn5 acetyltransferase) and ATAC (Ada Two A-containing). These two multiprotein complexes comprise complex-specific and shared subunits, which are organized in functional modules. The HAT module of ATAC is composed of GCN5, ADA2a, ADA3, and SGF29, whereas in the SAGA HAT module ADA2b is present instead of ADA2a. To better understand how the activity of human (h) hGCN5 is regulated in the two related, but different, HAT complexes we carried out in vitro HAT assays. We compared the activity of hGCN5 alone with its activity when it was part of purified recombinant hATAC or hSAGA HAT modules or endogenous hATAC or hSAGA complexes using histone tail peptides and full-length histones as substrates. We demonstrated that the subunit environment of the HAT complexes into which GCN5 incorporates determines the enhancement of GCN5 activity. On histone peptides we show that all the tested GCN5-containing complexes acetylate mainly histone H3K14. Our results suggest a stronger influence of ADA2b as compared with ADA2a on the activity of GCN5. However, the lysine acetylation specificity of GCN5 on histone tails or full-length histones was not changed when incorporated in the HAT modules of ATAC or SAGA complexes. Our results thus demonstrate that the catalytic activity of GCN5 is stimulated by subunits of the ADA2a- or ADA2b-containing HAT modules and is further increased by incorporation of the distinct HAT modules in the ATAC or SAGA holo-complexes. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families.

Science.gov (United States)

Bouzigon, Emmanuelle; Dizier, Marie-Hélène; Krähenbühl, Christine; Lemainque, Arnaud; Annesi-Maesano, Isabella; Betard, Christine; Bousquet, Jean; Charpin, Denis; Gormand, Frédéric; Guilloud-Bataille, Michel; Just, Jocelyne; Le Moual, Nicole; Maccario, Jean; Matran, Régis; Neukirch, Françoise; Oryszczyn, Marie-Pierre; Paty, Evelyne; Pin, Isabelle; Rosenberg-Bourgin, Myriam; Vervloet, Daniel; Kauffmann, Francine; Lathrop, Mark; Demenais, Florence

2004-12-15

A genome-wide scan for asthma phenotypes was conducted in the whole sample of 295 EGEA families selected through at least one asthmatic subject. In addition to asthma, seven phenotypes involved in the main asthma physiopathological pathways were considered: SPT (positive skin prick test response to at least one of 11 allergens), SPTQ score being the number of positive skin test responses to 11 allergens, Phadiatop (positive specific IgE response to a mixture of allergens), total IgE levels, eosinophils, bronchial responsiveness (BR) to methacholine challenge and %predicted FEV(1). Four regions showed evidence for linkage (P0.001): 6q14 for %FEV(1), 12p13 for IgE, 17q22-q24 for SPT and 21q21 for both SPTQ and %FEV(1). Nine other regions indicated smaller linkage signals (0.0010.005). While most of these regions have been reported by previous asthma and lung function screens, 6q14 appears to be a new region potentially linked to %FEV(1). To determine which of these various asthma phenotypes are more likely to share common genetic determinants, a principal component analysis was applied to the genome-wide LOD scores. This analysis revealed clustering of LODs for asthma, SPT and Phadiatop on one axis and clustering of LODs for %FEV(1), BR and SPTQ on the other, while LODs for IgE and eosinophils appeared to be independent from all other LODs. These results provide new insights into the potential sharing of genetic determinants by asthma-related phenotypes.

The Transfer of Cognitive Speed of Processing Training to Older Adults' Driving Mobility Across 5 Years.

Science.gov (United States)

Ross, Lesley A; Edwards, Jerri D; O'Connor, Melissa L; Ball, Karlene K; Wadley, Virginia G; Vance, David E

2016-01-01

Multilevel models assessed the effects of cognitive speed of processing training (SPT) on older adults' self-reported driving using intention-to-treat (ITT, randomization to training or control conditions) and dosage (treatment-received via number of training sessions) analyses across 5 years. Participants randomized to SPT (n = 598) were compared with those randomized to either the no-contact control (n = 598) or memory training, which served as an active control (n = 610). Driving mobility (frequency, exposure, and space) was assessed over time. No significant effects were found within the ITT analyses. However, number of SPT sessions did affect driving mobility outcomes. In the full sample (N = 1,806), higher SPT doses were associated with maintained driving frequency as compared with both control groups, but no effects were found for driving exposure or space. Subsample analyses (n = 315) revealed that persons at-risk for mobility declines (i.e., poor initial processing speed) who received additional booster SPT sessions reported greater maintenance of both driving frequency and exposure over time as compared with the no-contact and active control groups. These results and prior research indicate that cognitive SPT transfers to prolonged driving mobility among older adults. Future research should investigate the mechanisms behind transfer effects to real-world activities, such as driving. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Periodontal abscess during supportive periodontal therapy: a review of the literature.

Science.gov (United States)

Silva, Geraldo L M; Soares, Rodrigo V; Zenóbio, Elton G

2008-09-01

The aim of this review is to present the current status of the occurrence and management of a periodontal abscess during supportive periodontal therapy (SPT). A periodontal abscess depicts typical features and has been described in patients under SPT in clinical trials. Common periodontal pathogens have been observed in this lesion and some etiologic factors may be responsible for its recurrence. This condition can be isolated or associated with factors that can change the prognosis of affected teeth. Although it has been frequently noticed in untreated periodontitis, the periodontal abscess can also occur in patients under SPT and has been regarded as one of the possible complications of SPT. Patients with a high susceptibility to periodontal disease lost more teeth than those with a healthy periodontium. Early diagnosis and appropriate intervention for periodontal abscesses in patients under SPT are extremely important for the management of the periodontal abscess since this condition can lead to loss of the involved tooth. A single case of a tooth diagnosed with periodontal abscess that responds favorably to adequate treatment does not seem to affect its longevity. An accurate diagnosis and adequate treatment can preserve the longevity of affected teeth.

Solar power tower commercialization in the Southwest: A market and technical assessment

International Nuclear Information System (INIS)

Bradley, J.; DeGroat, K.; Tanner, S.

1995-01-01

This market and technical assessment illustrates that the Southwestern power market can support the commercialization needs of Solar Power Tower (SPT) technology over the next 10 to 15 years. Realizing full commercial development during this time is contingent on successful completion of Solar Two and development of an initial follow-on plant around 2000. After 2002, the power market will become increasingly robust, presenting new opportunities for SPT development. The important conclusion of this analysis is that SPT projects can reach a cost level that puts them at or below the expected norm of costs for their main competitor, combined cycle natural gas. This means that with the same competitive focus on minimizing costs and finding opportunities to be more competitive that characterize combined cycle project developers, SPT has a realistic chance of competing and winning market share. The ability of SPT technology to compete in this market will be greatly affected by the rate of cost-reductions and technological improvements, but perhaps as importantly, by the environmental and regulatory climate which will unfold over the next decade and the availability of low cost financing options

Towards a Complete Classification of Symmetry-Protected Topological Phases for Interacting Fermions in Three Dimensions and a General Group Supercohomology Theory

Science.gov (United States)

Wang, Qing-Rui; Gu, Zheng-Cheng

2018-01-01

The classification and construction of symmetry-protected topological (SPT) phases in interacting boson and fermion systems have become a fascinating theoretical direction in recent years. It has been shown that (generalized) group cohomology theory or cobordism theory gives rise to a complete classification of SPT phases in interacting boson or spin systems. The construction and classification of SPT phases in interacting fermion systems are much more complicated, especially in three dimensions. In this work, we revisit this problem based on an equivalence class of fermionic symmetric local unitary transformations. We construct very general fixed-point SPT wave functions for interacting fermion systems. We naturally reproduce the partial classifications given by special group supercohomology theory, and we show that with an additional B ˜H2(Gb,Z2) structure [the so-called obstruction-free subgroup of H2(Gb,Z2) ], a complete classification of SPT phases for three-dimensional interacting fermion systems with a total symmetry group Gf=Gb×Z2f can be obtained for unitary symmetry group Gb. We also discuss the procedure for deriving a general group supercohomology theory in arbitrary dimensions.

Experiment list: SRX150496 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available ein-Barr Virus 63040797,85.0,19.7,1435 GSM935417: Harvard ChipSeq GM12878 SPT20 std source_name=GM12878 || b...gId=165&q=GM12878 || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq || datat

Assessment of land-use change on streamflow using GIS, remote sensing and a physically-based model, SWAT

Directory of Open Access Journals (Sweden)

J. Y. G. Dos Santos

2014-09-01

Full Text Available This study aims to assess the impact of the land-use changes between the periods 1967−1974 and 1997−2008 on the streamflow of Tapacurá catchment (northeastern Brazil using the Soil and Water Assessment Tool (SWAT model. The results show that the most sensitive parameters were the baseflow, Manning factor, time of concentration and soil evaporation compensation factor, which affect the catchment hydrology. The model calibration and validation were performed on a monthly basis, and the streamflow simulation showed a good level of accuracy for both periods. The obtained R2 and Nash-Sutcliffe Efficiency values for each period were respectively 0.82 and 0.81 for 1967−1974, and 0.93 and 0.92 for the period 1997−2008. The evaluation of the SWAT model response to the land cover has shown that the mean monthly flow, during the rainy seasons for 1967−1974, decreased when compared to 1997−2008.

Optical Characterization of the SPT-3G Camera

Science.gov (United States)

Pan, Z.; Ade, P. A. R.; Ahmed, Z.; Anderson, A. J.; Austermann, J. E.; Avva, J. S.; Thakur, R. Basu; Bender, A. N.; Benson, B. A.; Carlstrom, J. E.; Carter, F. W.; Cecil, T.; Chang, C. L.; Cliche, J. F.; Cukierman, A.; Denison, E. V.; de Haan, T.; Ding, J.; Dobbs, M. A.; Dutcher, D.; Everett, W.; Foster, A.; Gannon, R. N.; Gilbert, A.; Groh, J. C.; Halverson, N. W.; Harke-Hosemann, A. H.; Harrington, N. L.; Henning, J. W.; Hilton, G. C.; Holzapfel, W. L.; Huang, N.; Irwin, K. D.; Jeong, O. B.; Jonas, M.; Khaire, T.; Kofman, A. M.; Korman, M.; Kubik, D.; Kuhlmann, S.; Kuo, C. L.; Lee, A. T.; Lowitz, A. E.; Meyer, S. S.; Michalik, D.; Montgomery, J.; Nadolski, A.; Natoli, T.; Nguyen, H.; Noble, G. I.; Novosad, V.; Padin, S.; Pearson, J.; Posada, C. M.; Rahlin, A.; Ruhl, J. E.; Saunders, L. J.; Sayre, J. T.; Shirley, I.; Shirokoff, E.; Smecher, G.; Sobrin, J. A.; Stark, A. A.; Story, K. T.; Suzuki, A.; Tang, Q. Y.; Thompson, K. L.; Tucker, C.; Vale, L. R.; Vanderlinde, K.; Vieira, J. D.; Wang, G.; Whitehorn, N.; Yefremenko, V.; Yoon, K. W.; Young, M. R.

2018-05-01

The third-generation South Pole Telescope camera is designed to measure the cosmic microwave background across three frequency bands (centered at 95, 150 and 220 GHz) with ˜ 16,000 transition-edge sensor (TES) bolometers. Each multichroic array element on a detector wafer has a broadband sinuous antenna that couples power to six TESs, one for each of the three observing bands and both polarizations, via lumped element filters. Ten detector wafers populate the detector array, which is coupled to the sky via a large-aperture optical system. Here we present the frequency band characterization with Fourier transform spectroscopy, measurements of optical time constants, beam properties, and optical and polarization efficiencies of the detector array. The detectors have frequency bands consistent with our simulations and have high average optical efficiency which is 86, 77 and 66% for the 95, 150 and 220 GHz detectors. The time constants of the detectors are mostly between 0.5 and 5 ms. The beam is round with the correct size, and the polarization efficiency is more than 90% for most of the bolometers.

Patterns of late spring frost leaf damage and recovery in a European beech (Fagus sylvatica L.) stand in south-eastern Germany based on repeated digital photographs.

Science.gov (United States)

Menzel, Annette; Helm, Raimund; Zang, Christian

2015-01-01

Damage by late spring frost is a risk deciduous trees have to cope with in order to optimize the length of their growing season. The timing of spring phenological development plays a crucial role, not only at the species level, but also at the population and individual level, since fresh new leaves are especially vulnerable. For the pronounced late spring frost in May 2011 in Germany, we studied the individual leaf development of 35 deciduous trees (mainly European beech Fagus sylvatica L.) at a mountainous forest site in the Bayerischer Wald National Park using repeated digital photographs. Analyses of the time series of greenness by a novel Bayesian multiple change point approach mostly revealed five change points which almost perfectly matched the expected break points in leaf development: (i) start of the first greening between day of the year (DOY) 108-119 (mean 113), (ii) end of greening, and (iii) visible frost damage after the frost on the night of May 3rd/4th (DOY 123/124), (iv) re-sprouting 19-38 days after the frost, and (v) full maturity around DOY 178 (166-184) when all beech crowns had fully recovered. Since frost damage was nearly 100%, individual susceptibility did not depend on the timing of first spring leaf unfolding. However, we could identify significant patterns in fitness linked to an earlier start of leaf unfolding. Those individuals that had an earlier start of greening during the first flushing period had a shorter period of recovery and started the second greening earlier. Thus, phenological timing triggered the speed of recovery from such an extreme event. The maximum greenness achieved, however, did not vary with leaf unfolding dates. Two mountain ashes (Sorbus aucuparia L.) were not affected by the low temperatures of -5°C. Time series analysis of webcam pictures can thus improve process-based knowledge and provide valuable insights into the link between phenological variation, late spring frost damage, and recovery within one stand.

COMPRESSIBLE 'TURBULENCE' OBSERVED IN THE HELIOSHEATH BY VOYAGER 2

International Nuclear Information System (INIS)

Burlaga, L. F.; Ness, N. F.

2009-01-01

This paper describes the multiscale structure of the compressible 'turbulence' observed in the high-resolution (48 s) observations of the magnetic field strength B made by Voyager 2 (V2) in the heliosheath behind the termination shock from 2007 DOY 245.0-300.8 and in a unipolar region from 2008 DOY 2.9-75.6. The magnetic field strength is highly variable on scales from 48 s to several hours in both intervals. The distributions of daily averages and 48 s averages of B are lognormal in the post-termination shock (TS) region and Gaussian in the unipolar region, respectively. The amplitudes of the fluctuations were greater in the post-TS region than in the unipolar region, at scales less than several hours. The multiscale structure of the increments of B is described by the q-Gaussian distribution of nonextensive statistical mechanics on all scales from 48 s to 3.4 hr in the unipolar region and from 48 s to 6.8 hr in the post-TS region, respectively. The amplitudes of the fluctuations of increments of B are larger in the post-TS region than in the unipolar region at all scales. The probability density functions of the increments of B are non-Gaussian at all scales in the unipolar region, but they are Gaussian at the largest scales in the post-TS region. Time series of the magnitude and direction of B show that the fluctuations are highly compressive. The small-scale fluctuations are a mixture of coherent structures (semi-deterministic structures) and random structures, which vary significantly from day to day. Several types of coherent structures were identified in both regions.

Re-assessing the likelihood of airborne spread of foot-and-mouth disease at the start of the 1967-1968 UK foot-and-mouth disease epidemic

DEFF Research Database (Denmark)

Gloster, J.; Freshwater, A.; Sellers, R.F.

2005-01-01

The likelihood of airborne spread of foot-and-mouth disease at the start of the 1967-1968 epidemic is re-assessed in the light of current understanding of airborne disease spread. The findings strongly confirm those made at the time that airborne virus was the most likely cause of the rapid early...... development of the disease out to 60 km from the source. This conclusion is reached following a detailed epidemiological, meteorological and modelling study using original records and current modelling techniques. The role played by 'lee waves' as the mechanism for the spread is investigated. It is thought...... that they played little part in influencing the development of the epidemic. A number of lessons learned from the work are drawn, identifying the need for further research on the quantity and characteristics I of airborne virus. The results are also used to illustrate what advice would have been available...

Levantamento epidemiológico e virológico de casos suspeitos de poliomielite no Hospital Estadual Jesus, no período de janeiro de 1967 a março de 1968

Directory of Open Access Journals (Sweden)

Hermann G. Schatzmayr

1968-10-01

Full Text Available Os autores apresentam os resultados de isolamento de poliovírus de crianças com suspeita de poliomielite paralítica no Isolamento do Hospital Estadual Jesus do Estado da Guanabara. Nas 188 amostras computadas apresentaram-se 79 positivas, destas 73,5% de poliovírus tipo I, 25,3% do tipo II e 1,2% do tipo III. Os autores mostram no Gráfico 1, um aumento da incidência da poliomielite a partir dos últimos meses no ano de 1967. Chamam a atenção para o grande número de casos no grupo etário de 0-3 anos (Gráfico 2; colocam ainda em questão o melhor equacionamento do problema das vacinações (Tabela 1, com estudos laboratoriais de avaliação da vacina Sabin. O estudo da procedência e sexo das crianças não permitiu maiores conclusões, sendo levantada também a relação da idade com a incidência da poliomielite (Tabela 2, bem como a necessidade de se realizar estudos para outros enterovírus, presentes na população infantil da área estudada.

AcEST: BP915793 [AcEST

Lifescience Database Archive (English)

Full Text Available glycoprotein OS=Ivory Coast ebolavi... 30 8.4 >sp|Q21338|SPT5H_CAEEL Transcription elongation factor SPT5 O...LFQRTT 119 >sp|Q66810|VGP_EBOIC Envelope glycoprotein OS=Ivory Coast ebolavirus (strain Cote d'Ivoire-94) GN

Association between vitamin D levels and allergy-related outcomes vary by race and other factors.

Science.gov (United States)

Wegienka, Ganesa; Havstad, Suzanne; Zoratti, Edward M; Kim, Haejin; Ownby, Dennis R; Johnson, Christine Cole

2015-11-01

Allergy-related studies that include biological measurements of vitamin D preceding well-measured outcomes are needed. We sought to examine the associations between early-life vitamin D levels and the development of allergy-related outcomes in the racially diverse Wayne County Health, Environment, Allergy, and Asthma Longitudinal Study birth cohort. 25-Hydroxyvitamin D (25[OH]D) levels were measured in stored blood samples from pregnancy, cord blood, and age 2 years. Logistic regression models were used to calculate odds ratios (ORs) with 95% CIs for a 5 ng/mL increase in 25(OH)D levels for the following outcomes at age 2 years: eczema, skin prick tests (SPTs), increased allergen-specific IgE level (≥ 0.35 IU/mL), and doctor's diagnosis of asthma (3-6 years). Prenatal 25(OH)D levels were inversely associated with eczema (OR, 0.85; 95% CI, 0.75-0.96). The association was stronger in white children (white children: OR, 0.79; 95% CI, 0.57-1.09; black children: OR, 0.96; 95% CI, 0.82-1.12), although this was not statistically significant. Cord blood 25(OH)D levels were inversely associated with having 1 or more positive SPT responses and aeroallergen sensitization. Both associations were statistically significant in white children (positive SPT response: OR, 0.50; 95% CI, 0.32-0.80; ≥ 1 aeroallergen sensitization: OR, 0.50; 95% CI, 0.28-0.92) in contrast with black children (positive SPT response: OR, 0.88; 95% CI, 0.68-1.14; ≥ 1 aeroallergen sensitization: OR, 0.85; 95% CI, 0.65-1.11). 25(OH)D levels measured concurrently with outcome assessment were inversely associated with aeroallergen sensitization (OR, 0.79; 95% CI, 0.66-0.96) only among black children (white children: OR, 1.21; 95% CI, 0.87-1.69). Prenatal and cord blood 25(OH)D levels were associated with some allergy-related outcomes, with a general pattern indicating that children with higher 25(OH)D levels tend to have fewer allergy-related outcomes. Copyright © 2015 American Academy of Allergy

Warfighter Information Network-Tactical Increment 2 (WIN-T Inc 2)

Science.gov (United States)

2015-12-01

Company- level . Using equipment mounted on combat platforms, WIN-T Inc 2 delivers a mobile capability that reduces reliance on fixed infrastructure...Cost Estimate Reference Army Cost Position (ACP) dated April 28, 2015 Confidence Level Confidence Level of cost estimate for current APB: 50% The...Development Estimate Changes PAUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total 2.064 -0.055 -0.063 0.016 0.000 0.093 0.000 0.200 0.191 2.255

Matrix product states and equivariant topological field theories for bosonic symmetry-protected topological phases in (1+1) dimensions

Energy Technology Data Exchange (ETDEWEB)

Shiozaki, Ken [Department of Physics, University of Illinois at Urbana Champaign,1110 West Green Street, Urbana, IL 61801 (United States); Ryu, Shinsei [James Franck Institute and Kadanoff Center for Theoretical Physics, University of Chicago,5640 South Ellis Ave, Chicago, IL 60637 (United States)

2017-04-18

Matrix Product States (MPSs) provide a powerful framework to study and classify gapped quantum phases — symmetry-protected topological (SPT) phases in particular — defined in one dimensional lattices. On the other hand, it is natural to expect that gapped quantum phases in the limit of zero correlation length are described by topological quantum field theories (TFTs or TQFTs). In this paper, for (1+1)-dimensional bosonic SPT phases protected by symmetry G, we bridge their descriptions in terms of MPSs, and those in terms of G-equivariant TFTs. In particular, for various topological invariants (SPT invariants) constructed previously using MPSs, we provide derivations from the point of view of (1+1) TFTs. We also discuss the connection between boundary degrees of freedom, which appear when one introduces a physical boundary in SPT phases, and “open” TFTs, which are TFTs defined on spacetimes with boundaries.

Sleeve Push Technique: A Novel Method of Space Gaining.

Science.gov (United States)

Verma, Sanjeev; Bhupali, Nameksh Raj; Gupta, Deepak Kumar; Singh, Sombir; Singh, Satinder Pal

2018-01-01

Space gaining is frequently required in orthodontics. Multiple loops were initially used for space gaining and alignment. The most common used mechanics for space gaining is the use of nickel-titanium open coil springs. The disadvantage of nickel-titanium coil spring is that they cannot be used until the arches are well aligned to receive the stiffer stainless steel wires. Therefore, a new method of gaining space during initial alignment and leveling has been developed and named as sleeve push technique (SPT). The nickel-titanium wires, i.e. 0.012 inches and 0.014 inches along with archwire sleeve (protective tubing) can be used in a modified way to gain space along with alignment. This method helps in gaining space right from day 1 of treatment. The archwire sleeve and nickel-titanium wire in this new SPT act as a mutually synergistic combination and provide the orthodontist with a completely new technique for space opening.

Sleeve push technique: A novel method of space gaining

Directory of Open Access Journals (Sweden)

Sanjeev Verma

2018-01-01

Full Text Available Space gaining is frequently required in orthodontics. Multiple loops were initially used for space gaining and alignment. The most common used mechanics for space gaining is the use of nickel–titanium open coil springs. The disadvantage of nickel–titanium coil spring is that they cannot be used until the arches are well aligned to receive the stiffer stainless steel wires. Therefore, a new method of gaining space during initial alignment and leveling has been developed and named as sleeve push technique (SPT. The nickel–titanium wires, i.e. 0.012 inches and 0.014 inches along with archwire sleeve (protective tubing can be used in a modified way to gain space along with alignment. This method helps in gaining space right from day 1 of treatment. The archwire sleeve and nickel–titanium wire in this new SPT act as a mutually synergistic combination and provide the orthodontist with a completely new technique for space opening.

[Allergens used in skin tests in Mexico].

Science.gov (United States)

Larenas Linnemann, Désirée; Arias Cruz, Alfredo; Guidos Fogelbach, Guillermo Arturo; Cid del Prado, Mari Lou

2009-01-01

Immunotherapy is the only recognized causal treatment for allergies. It is prepared on an individual basis, based on the patient's clinical history and the result of the skin prick test (SPT). An adequate composition of the allergens with which to test the patient is crucial for an optimal diagnosis. To know allergens used in tests in allergy practices in Mexico. A national survey among all members of the Colegio Mexicano de Inmunología Clínica y Alergia (CMICA) and of the Colegio Mexicano de Pediatras Especialistas en Inmunología Clínica y Alergia (COMPEDIA) was carried out. In a second phase respondents were asked to send in the composition of a routine SPT in their clinic. The results are presented descriptively and the frequency is calculated by which certain allergen is tested in the interviewed practices. A survey response rate of 61 (17%) was obtained and 54% showed their SPT content. Weeds' representation in the SPT seems adequate; Atriplex is tested in all allergy practices. Some trees that show cross-reactivity might be eliminated from the SPT, but 20% doesn't test for Cynodon nor Holcus, and 25% doesn't for important allergens as cat, dog and cockroach. House dust and tobacco are still tested with certain frequency. The selection of which allergens to test in a SPT is based on multiple data, that change continuously with new investigations and discoveries. Our specialty is the most indicated--and obligated--to adjust constantly to these changes to have the best diagnostic tool to detect specific allergies.

Navy Multiband Terminal (NMT)

Science.gov (United States)

2015-12-01

AEHF satellites and MILSTAR satellites in the backwards-compatible mode. Mission requirements specific to Navy operations, including threat levels and...Center for Cost Analysis (NCCA) Component Cost Position (CCP) memo dated December 18, 2015 Confidence Level Confidence Level of cost estimate for... Econ Qty Sch Eng Est Oth Spt Total 6.970 0.082 0.637 0.034 0.000 -1.210 0.000 -0.418 -0.875 6.095 Current SAR Baseline to Current Estimate (TY $M) PAUC

Psychological, behavioral, and clinical effects of intra-oral camera: a randomized control trial on adults with gingivitis.

Science.gov (United States)

Araújo, Mário-Rui; Alvarez, Maria-João; Godinho, Cristina A; Pereira, Cícero

2016-12-01

To evaluate the effects of using an intra-oral camera (IOC) during supportive periodontal therapy (SPT), on the psychological, behavioral, and clinical parameters of patients with gingivitis, outlined by evidence and a theory-based framework. A group of 78 adult patients with gingivitis receiving an SPT was randomized into two groups: IOC and control. Bleeding on Marginal Probing (BOMP), self-reported dental hygiene behaviors, and psychological determinants of behavior change (outcome expectancies, self-efficacy, and planning) and IOC opinion were evaluated 1 week before or during the appointment and 4 months later. Repeated-measures anova was used to compare groups over time. Almost all the patients brushed their teeth daily, while 78% either never or hardly ever used dental floss. The IOC group showed significant improvements in BOMP index (P < 0.001), self-reported flossing (P < 0.05), and self-efficacy (P < 0.05) compared to the control group. The use of IOC significantly improves clinical, behavioral, and psychological determinants of periodontal health 4 months after treatment. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Core features of personality disorder: differentiating general personality dysfunctioning from personality traits

NARCIS (Netherlands)

Berghuis, H.; Kamphuis, J.H.; Verheul, R.

2012-01-01

The distinction between general personality dysfunctioning (GPD) and specific personality traits (SPT) is an important focus of attention in the proposed revisions of the DSM-5. The present study explores the distinction between GPD and SPT using the self-report questionnaires General Assessment of

Two-photon excited fluorescence imaging of the pancreatic solid pseudopapillary tumor without hematoxylin and eosin stains.

Science.gov (United States)

Xu, Yahao; Liao, Chenxi; Chen, Jing; Chen, Youting; Zhu, Xiaoqin; Chen, Jianxin

2016-05-01

Solid pseudopapillary tumor (SPT) of the pancreas is an epithelial tumor with low-grade malignant potential and present more common in females. At present, the gold standard for accurate diagnosis of pancreatic tumor was mostly depending on the pathological and/or cytological evaluation. In this work, TPEF microscopy was applied to obtain the images of human normal pancreas and SPT of the pancreas without hematoxylin and eosin (H&E) staining, for the purpose of identifying the organization structural, cell morphological, and cytoplasm changing, which were then compared to their corresponding H&E stained histopathological results. Our results showed that high-resolution TPEF imaging of the pancreatic SPT can clearly distinguish the pathological features from normal pancreas in unstained histological sections, and the results are consistent with the histological results. Moreover, we measured the nuclear-cytoplasmic ratios of the pancreatic SPT and normal pancreas to characterize their difference in the cytomorphological feature. It indicated that this technique can achieve the consistent information of pathological diagnosis, and has the potential to substantially improve the optical diagnosis and treatment of the pancreatic SPT without H&E staining in the future. SCANNING 38:245-250, 2016. © 2015 Wiley Periodicals, Inc. © Wiley Periodicals, Inc.

ANALISIS MODEL PENERIMAAN PENGGUNA SISTEM PELAPORAN PAJAK ONLINE

Directory of Open Access Journals (Sweden)

Muhammad Malik Hakim

2016-04-01

Full Text Available Direktorat Jenderal Pajak saat ini telah menerapkan e-SPT dan e-Filing sebagai sarana digitalisasi dan otomasi pelaporan pajak. Untuk meningkatkan transformasi bisnis proses dalam sistem pelayanan perpajakan dari sistem manual ke digital, diperlukan kesiapan dan penerimaan pengguna yang cukup memadai. Studi dan analisis perlu dilakukan untuk mengetahui sejauh mana tingkat penerimaan pengguna dalam menggunakan sistem e-SPT dan e- Filing. Studi dilakukan secara kuantitatif menggunakan model UTAUT yang telah dimodifikasi untuk menganalisis model penerimaan pengguna yang merupakan Wajib Pajak Orang Pribadi yang telah menggunakan e-SPT dan e- Filing. Jumlah responden dalam penelitian ini sejumlah 235 responden yang disebarkan dengan cara snow ball sampling. Hasil penelitian menunjukkan perbedaan model penerimaan e-SPT dan e-Filing dari jenis kelamin dan kelompok umur. Pengaruh harapan kinerja (PE dan pengaruh sosial (SI terhadap niat perilaku (BI, serta pengaruh niat perilaku (BI pada penggunaan aktual (AU pada pria lebih kuat dibandingkan pada wanita. Sebaliknya, pengaruh harapan usaha (EE terhadap niat perilaku (BI dan fasilitas pendukung / penunjang (FC terhadap penggunaan aktual (AU pada wanita dijumpai memberikan pengaruh yang lebih kuat. Selain itu, di dalam kelompok umur, pengaruh terhadap semua variabel yang diteliti ternyata lebih kuat pada kelompok umur 25 35 tahun. Kata kunci: model penerimaan pengguna, UTAUT, pelaporan pajak, e-SPT, e-filing.

Cosmogenic nuclides in recently fallen meteorites: Evidence for galactic cosmic ray variations during the period 1967--1978

International Nuclear Information System (INIS)

Evans, J.C.; Reeves, J.H.; Rancitelli, L.A.; Bogard, D.D.

1982-01-01

Cosmogenic radionuclides were measured on 48 fragments of 24 meteorites which fell between 1967 and 1978. Nondestructive gamma counting techniques were used to obtain data on 7 Be, 46 Sc, 48 V, 51 Cr, 54 Mn, 56 Co, 57 Co, 58 Co, and 60 Co on at least some of the samples. Sodium 22 and 26 Al measurements are reported on all 48 samples. In addition, new rare gas data and exposure ages are reported for the meteorites Guibga, Gorlovka, Dhajala, Louisville, Acapulco, Jilin, Kabo, Alta-Ameen, and Canon City. The cosmogenic radioisotope and rare gas data are interpreted in terms of a time dependent modulation of galactic cosmic rays spanning one full 11 year sun spot cycle. Special attention is given to the data on 22 Na, 46 Sc, 54 Mn, and 48 V with either 26 Al or 22 Ne/ 21 Ne used to provide a shielding correction. The shielding normalized data using the 26 Al method appear to correlate well with calculated production rates scaled against the Deep River neutron monitor. The data for the four isotopes are consistent with a production rate variation of a factor of 2.5--3 between solar maximum and solar minimum for sun spot cycle 20. These data demonstrate that the production rates of cosmic ray-produced nuclides in meteorites vary considerably according to modulation by the 11-year solar cycle and support the concept that variations of solar-modulated, cosmic ray flux of similar magnitude have occurred over much longer time periods

THE GROWTH OF COOL CORES AND EVOLUTION OF COOLING PROPERTIES IN A SAMPLE OF 83 GALAXY CLUSTERS AT 0.3 < z < 1.2 SELECTED FROM THE SPT-SZ SURVEY

Energy Technology Data Exchange (ETDEWEB)

McDonald, M.; Bautz, M. W. [Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139 (United States); Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Crawford, T. M.; Crites, A. T. [Kavli Institute for Cosmological Physics, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Vikhlinin, A.; Stalder, B.; Ashby, M. L. N.; Bayliss, M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); De Haan, T. [Department of Physics, McGill University, 3600 Rue University, Montreal, Quebec H3A 2T8 (Canada); Lin, H. W. [Caddo Parish Magnet High School, Shrevport, LA 71101 (United States); Aird, K. A. [University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Bocquet, S.; Desai, S. [Department of Physics, Ludwig-Maximilians-Universitaet, Scheinerstr. 1, D-81679 Muenchen (Germany); Brodwin, M. [Department of Physics and Astronomy, University of Missouri, 5110 Rockhill Road, Kansas City, MO 64110 (United States); Cho, H. M. [NIST Quantum Devices Group, 325 Broadway Mailcode 817.03, Boulder, CO 80305 (United States); Clocchiatti, A., E-mail: mcdonald@space.mit.edu [Departamento de Astronomia y Astrosifica, Pontificia Universidad Catolica (Chile); and others

2013-09-01

We present first results on the cooling properties derived from Chandra X-ray observations of 83 high-redshift (0.3 < z < 1.2) massive galaxy clusters selected by their Sunyaev-Zel'dovich signature in the South Pole Telescope data. We measure each cluster's central cooling time, central entropy, and mass deposition rate, and compare these properties to those for local cluster samples. We find no significant evolution from z {approx} 0 to z {approx} 1 in the distribution of these properties, suggesting that cooling in cluster cores is stable over long periods of time. We also find that the average cool core entropy profile in the inner {approx}100 kpc has not changed dramatically since z {approx} 1, implying that feedback must be providing nearly constant energy injection to maintain the observed ''entropy floor'' at {approx}10 keV cm{sup 2}. While the cooling properties appear roughly constant over long periods of time, we observe strong evolution in the gas density profile, with the normalized central density ({rho}{sub g,0}/{rho}{sub crit}) increasing by an order of magnitude from z {approx} 1 to z {approx} 0. When using metrics defined by the inner surface brightness profile of clusters, we find an apparent lack of classical, cuspy, cool-core clusters at z > 0.75, consistent with earlier reports for clusters at z > 0.5 using similar definitions. Our measurements indicate that cool cores have been steadily growing over the 8 Gyr spanned by our sample, consistent with a constant, {approx}150 M{sub Sun} yr{sup -1} cooling flow that is unable to cool below entropies of 10 keV cm{sup 2} and, instead, accumulates in the cluster center. We estimate that cool cores began to assemble in these massive systems at z{sub cool}=1.0{sup +1.0}{sub -0.2}, which represents the first constraints on the onset of cooling in galaxy cluster cores. At high redshift (z {approx}> 0.75), galaxy clusters may be classified as ''cooling flows

Guided Multiple Launch Rocket System/Guided Multiple Launch Rocket System Alternative Warhead (GMLRS/GMLRS AW)

Science.gov (United States)

2015-12-01

Physical Configuration Audit for the GMLRS AW was completed at the system level in March 2015. ​Director of Operational Test and Evaluation Assessment...Confidence Level Confidence Level of cost estimate for current APB: 50% The confidence level used in establishing the cost estimate for GMLRS/GMLRS AW...PAUC Development Estimate Changes PAUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total 0.039 -0.003 0.001 0.001 0.009 0.037 0.000 0.000 0.045

AGM-88E Advanced Anti-Radiation Guided Missile (AGM-88E AARGM)

Science.gov (United States)

2015-12-01

0.0 0.0 Acq O&M 0.0 0.0 -- 0.0 0.0 0.0 0.0 Total 1528.5 1661.1 N/A 2107.4 1861.4 2026.2 2663.7 1 APB Breach Confidence Level Confidence Level of...normal conditions, encountering average levels of technical, schedule, and programmatic risk and external interference. Based on the rigor in methods...SAR Baseline to Current SAR Baseline (TY $M) Initial PAUC Development Estimate Changes PAUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total

The José de Figueiredo Institute role on the recovery of paintings from the Gulbenkian collection after the 1967 flood at the Pombal Palace, in Oeiras

Directory of Open Access Journals (Sweden)

Mercês Lorena

2017-01-01

Full Text Available Before the opening of the Calouste Gulbenkian Museum in 1969, much of the Gulbenkian collection was displayed and stored at the Pombal Palace, in Oeiras. The 1967 flood was one of the greatest calamities that hit this collection. Of the 70 paintings that were kept in the safety deposit, and which were damaged by water and mud, two-thirds required special care, including two paintings that were considered irrecoverable: "Virgin with the child and Donors", by Vittore Carpaccio, and the "Island of S. Pietro di Castello", by Francesco Guardi. The José de Figueiredo Institute immediately began the salvage intervention that certain paintings required, using techniques and products internationally recognized and proven by the long years of their experience. An individual file process was prepared for each work, including a photographic and radiographic documentation plus a detailed description of the intervention procedure.

Respuesta de Physalis peruviana a la fertilización con diferentes dosis de N, P y K en el Altiplano de Pasto, Colombia

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Amanda Silva Parra

2015-10-01

Full Text Available En un Andisol Typic dystrandept del Altiplano de Pasto (2800 m.s.n.m., 12.6°C, 820 mm/año y 900 h de luz solar, Colombia, se evaluaron algunas variables de crecimiento, contenido de nutrientes y producción de uvilla (Physalis peruviana como respuesta a la fertilización con N, P y K. Los tratamientos consistieron en la aplicación de urea (46% N como fuente de N, superfosfato triple-SPT (46% de P2O5 como fuente de P y cloruro de potasio-KCl (60% K2O como fuente de K, en dosis iguales para cada fuente, de 80, 150 y 300 kg/ha/año aplicados en dos épocas al momento del trasplante y 30 días después, antes de la floración. Los resultados mostraron diferencias en fuentes y dosis (P ≤ 0.01 en todas las variables analizadas. Las dosis de 300 kg/ha de urea, 150 kg/ha de SPT y 300 kg/ha de KCl favorecieron la mayor altura de planta, la materia seca y la absorción de NPK (P ≤ 0.05. La absorción de N fue mayor que la de K y éste a su vez que la de P en todas las interacciones evaluadas (P ≤ 0.05. La aplicación de 300 kg/ha de cada uno de los fertilizantes ocasiono incremento del rendimiento de P. peruviana. Por otra parte, fueron encontrados efectos positivos en la absorción NPK en relación con los rendimientos de Physalis peruviana con 300 kg/ha de urea, 150 kg/ha de SPT y 300 kg/ha de KCl (P ≤ 0.05, por tanto se recomiendan estas dosis de fertilizantes.

Survey on the role of brown hares (Lepus europaeus, Pallas 1778 as carriers of zoonotic dermatophytes

Directory of Open Access Journals (Sweden)

Francesca Mancianti

2010-02-01

Full Text Available The occurrence of dermatophytes and keratinophilic fungi was investigated by hair-brush technique on the coat of 986 apparently healthy brown hares (Lepus europaeus, Pallas 1778 caught in 9 restocking and capture zones in Central Italy. Overall, 7.5% hair samples gave positive results. Trichophyton terrestre (2.1%, Chrysosporium sp, Chrysosporium keratinophilum, Microsporum gypseum, Trichophyton gloriae and Trichophyton mentagrophytes (0.6% each, Trichophyton erinacei and Scopulariopsis brevicaulis (0.4% each, Chrysosporium asperatum (0.3%, Arthroderma sp and Microsporum canis (0.1% each were identified in cultures with single isolates, whereas Chrysosporium sp/T. mentagrophytes (0.3%, Chrysosporium sp/T. terrestre and M. gypseum/T. terrestre (0.2% each, Chrysosporium tropicum/T. terrestre, M. canis/T. terrestre and T. ajelloi/T. terrestre (0.1% each were identified in cultures with mixed isolates. T. erinacei and M. canis have not previously been isolated from hares. M. canis, T. erinacei and T. mentagrophytes were the most clinically important dermatophytes found. Altogether, they were isolated only from 1.5% hair samples. Thus, it is concluded that brown hares may play a limited epidemiological role as carriers of zoonotic dermatophytes. Nevertheless, this should be taken into consideration as many people may be exposed to zoonotic agents from brown hares during hunting and trapping activities.

Effect of tribulus terrestris saponins on behavior and neuroendocrine in chronic mild stress depression rats.

Science.gov (United States)

Wang, Zhe; Zhang, Dongdong; Hui, Shan; Zhang, Yingjin; Hu, Suiyu

2013-04-01

To observe the effect of tribulus terrestris saponins (TTS) on behavior and neuroendocrine of chronic mild stress (CMS) depression rats. Thirty male Sprague-Dawley rats were randomly allocated to six groups: vehicle group, CMS group, CMS + fluoxetine group and CMS + TTS of low-dosage (0.375 g/kg), medium-dosage (0.75 g/kg) and high-dosage (2.25 g/kg) groups. All rats except the vehicle group singly housed and exposed an unpredicted sequence of mild stressors. The behavior of rats was detected by open-field test (OFT) and sucrose preference test (SPT). The concentration of corticotropin-releasing factor (CRF) and adrenocorticotropic hormone (ACTH) in serum of the rats were detected by radioimmunoassay. The concentration of cortisol (CORT) in serum was detected by enzyme immunoassay. CMS procedure not only significantly decreased the scores of crossing, rears and grooming in OFT and the sucrose preference in SPT (all P < 0.01), but also markedly increased serum CRH and CORT levels (both P < 0.05). Treatment with TTS (0.75 and 2.25 g/kg) could significantly prevent all of these abnormalities induced by CMS (P < 0.05, P < 0.01). CMS can affect rat behavior and neuroendocrine and cause depression. TTS has the antagonism on CMS and produce antidepressive effects.

Tactical Tomahawk RGM-109E/UGM-109E Missile (TACTOM)

Science.gov (United States)

2015-12-01

2004: Operational Requirements Document for Tomahawk Weapons Systems Baseline IV signed. TACTOM is authorized in Chapter 2 of this system level ...5124.8 3290.3 6885.4 6390.4 1 APB Breach Confidence Level Confidence Level of cost estimate for current APB: 51% The estimate to support this program...Development Estimate Changes PAUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total 1.365 -0.015 0.324 0.117 0.000 -0.716 0.000 0.104 -0.186 1.179

Phosphorus kinetics in ovine fed with different phosphorus sources, using the isotopic dilution technique

International Nuclear Information System (INIS)

Vitti, D.M.S.S.; Abdalla, A.L.; Meirelles, C.F.

1992-01-01

Phosphorus kinetics in fluids and tissues of sheep was studied. Sixteen castrated sheep were kept in metabolism cages, receiving a semipuried diet containing as phosphorus sources dicalcium phosphate (BIC), monoammonium phosphate (MAP), superphosphate (SPT) and Tapita phosphate (TAP) 200 μCi P-32 was intravenously injected in each sheep and blood and feces were collected for eight days. From the specific activities in feces and plasma the endogenous phosphorus and the absorption coefficient were calculated. plasma P-32 half-life was determined. Nine days after injection the animals were killed and liver, kidney and muscle and bone samples were collected. P-32 retention and specific activities in tissues were determined. Endogenous phosphorus and absorption coefficient values were 54.44 ± 15.31 mh/kg live weight and 0.60; 47.98 ± 12.44 and 0.56; 39.70 ± 7.29 and 0.49; 59.11 ± 17.12 and 0.58 respectively bor BIC, MAP, TAP and SPT. P-32 retention by tissues was 0.29 ± 0.09; 0.27 ± 0.06; 0.16 ± 0.04 and 0.08 ± 0.03 dose/g fresh matter, respectively for bone, liver, kidney and muscle. It was concluded that animals which received TAP showed differences in absorption, distribution and P-32 retention by fluids and tissues. Phosphorus availability was lower for this source. (author)

Phosphorus kinetics in ovine fed with different phosphorus sources, using the isotopic dilution technique; Cinetica do fosforo em ovinos suplementados com diferentes fontes fosfatadas, atraves da tecnica de diluicao isotopica

Energy Technology Data Exchange (ETDEWEB)

Vitti, D M.S.S.; Abdalla, A L [Centro de Energia Nuclear na Agricultura (CENA), Piracicaba, SP (Brazil); Meirelles, C F [Sao Paulo Univ., Piracicaba, SP (Brazil). Escola Superior de Agricultura Luiz de Queiroz

1992-06-01

Phosphorus kinetics in fluids and tissues of sheep was studied. Sixteen castrated sheep were kept in metabolism cages, receiving a semipuried diet containing as phosphorus sources dicalcium phosphate (BIC), monoammonium phosphate (MAP), superphosphate (SPT) and Tapita phosphate (TAP) 200 {mu}Ci P-32 was intravenously injected in each sheep and blood and feces were collected for eight days. From the specific activities in feces and plasma the endogenous phosphorus and the absorption coefficient were calculated. plasma P-32 half-life was determined. Nine days after injection the animals were killed and liver, kidney and muscle and bone samples were collected. P-32 retention and specific activities in tissues were determined. Endogenous phosphorus and absorption coefficient values were 54.44 {+-} 15.31 mh/kg live weight and 0.60; 47.98 {+-} 12.44 and 0.56; 39.70 {+-} 7.29 and 0.49; 59.11 {+-} 17.12 and 0.58 respectively bor BIC, MAP, TAP and SPT. P-32 retention by tissues was 0.29 {+-} 0.09; 0.27 {+-} 0.06; 0.16 {+-} 0.04 and 0.08 {+-} 0.03 dose/g fresh matter, respectively for bone, liver, kidney and muscle. It was concluded that animals which received TAP showed differences in absorption, distribution and P-32 retention by fluids and tissues. Phosphorus availability was lower for this source. (author) 14 refs., 1 tab.

Yoga as a Therapeutic Intervention: A Bibliometric Analysis of Published Research Studies from 1967 to 2013

Science.gov (United States)

Slutsky, Jeremiah; Singh, Nilkamal; Khalsa, Sat Bir S.

2015-01-01

Abstract Objective: A comprehensive bibliometric analysis was conducted on publications for yoga therapy research in clinical populations. Methods: Major electronic databases were searched for articles in all languages published between 1967 and 2013. Databases included PubMed, PsychInfo, MEDLINE, IndMed, Indian Citation Index, Index Medicus for South-East Asia Region, Web of Knowledge, Embase, EBSCO, and Google Scholar. Nonindexed journals were searched manually. Key search words included yoga, yoga therapy, pranayama, asana. All studies met the definition of a clinical trial. All styles of yoga were included. The authors extracted the data. Results: A total of 486 articles met the inclusion criteria and were published in 217 different peer-reviewed journals from 29 different countries on 28,080 study participants. The primary result observed is the three-fold increase in number of publications seen in the last 10 years, inclusive of all study designs. Overall, 45% of the studies published were randomized controlled trials, 18% were controlled studies, and 37% were uncontrolled studies. Most publications originated from India (n=258), followed by the United States (n=122) and Canada (n=13). The top three disorders addressed by yoga interventions were mental health, cardiovascular disease, and respiratory disease. Conclusion: A surge in publications on yoga to mitigate disease-related symptoms in clinical populations has occurred despite challenges facing the field of yoga research, which include standardization and limitations in funding, time, and resources. The population at large has observed a parallel surge in the use of yoga outside of clinical practice. The use of yoga as a complementary therapy in clinical practice may lead to health benefits beyond traditional treatment alone; however, to effect changes in health care policy, more high-quality, evidence-based research is needed. PMID:26196166

Financiamento à Inovação no Brasil: análise da aplicação dos recursos do Fundo Nacional de Desenvolvimento Científico e Tecnológico (FNDCT e da Financiadora de Estudos e Projetos (FINEP de 1967 a 2006

Directory of Open Access Journals (Sweden)

Luiz Martins de Melo

2009-10-01

Full Text Available The current work is focused on analyzing the innovation financing activities through the analysis of the outlays of the Fundo Nacional de Desenvolvimento Científico e Tecnológico – FNDCT (Funding for Scientific and Technological Development and also through Financiadora de Estudos de Projetos – FINEP (Research and Projects Financing during 1967-2006. Based on the concept of National System of Innovation a division in two periods will be proposed, which are 1967-1997 and 1998-2006, that has its landmark in the institutional change which created the sectoral funds as the primary source of funds to the FNDCT as well as setting up of a new governance to manage them. In order to understand those changes a comparison between the two periods will be made to point out the main features in both periods, that influenced the allocation of funds to FNDCT and FINEP and how those different features influenced the general priorities of FNDCT and FINEP outlays in each period. The conclusion points out to a higher average outlay per year and a priority to finance Brazilian owned firms in the first period. Despite the increase in the tax collection to sectoral funds in the second period, the amount of resources at disposal of the FNDCT and FINEP were hindered by a very tight macroeconomic policy, and by the lack of operational integration among the financial instruments to support innovation.O presente trabalho tem como objetivo analisar o financiamento das atividades de inovação por meio da aplicação dos recursos do Fundo Nacional de Desenvolvimento Científico e Tecnológico (FNDCT e da Financiadora de Estudos de Projetos (FINEP, de 1967 a 2006. Com base no conceito de Sistema Nacional de Inovação, é apresentada uma divisão em dois períodos, 1967-1997 e 1998-2006, cujo centro é a mudança institucional que criou os fundos setoriais como fonte primária de recursos para o FNDCT e, conjuntamente, a mudança na sua governança. Uma compara

Note: Time-gated 3D single quantum dot tracking with simultaneous spinning disk imaging

International Nuclear Information System (INIS)

DeVore, M. S.; Stich, D. G.; Keller, A. M.; Phipps, M. E.; Hollingsworth, J. A.; Goodwin, P. M.; Werner, J. H.; Cleyrat, C.; Lidke, D. S.; Wilson, B. S.

2015-01-01

We describe recent upgrades to a 3D tracking microscope to include simultaneous Nipkow spinning disk imaging and time-gated single-particle tracking (SPT). Simultaneous 3D molecular tracking and spinning disk imaging enable the visualization of cellular structures and proteins around a given fluorescently labeled target molecule. The addition of photon time-gating to the SPT hardware improves signal to noise by discriminating against Raman scattering and short-lived fluorescence. In contrast to camera-based SPT, single-photon arrival times are recorded, enabling time-resolved spectroscopy (e.g., measurement of fluorescence lifetimes and photon correlations) to be performed during single molecule/particle tracking experiments

An evaluation of the diagnostic value of different skin tests with egg in clinically egg-allergic children having atopic dermatitis

DEFF Research Database (Denmark)

Hansen, Tine K; Høst, Arne; Bindslev-Jensen, Carsten

2004-01-01

Skin testing is a common diagnostic procedure in food allergy, but the final diagnosis of food allergy is based on the clinical response to food challenge. We studied the value of the skin prick-prick test (SPT), skin application food test (SAFT) and atopy patch test (APT) with fresh egg extract......-allergic children were positive in SPT and 40-60% in APT. In APT and in SPT false-positive reactions to egg were observed. In this study comprising a small number of patients including control subjects, neither SAFT nor APT with fresh whole egg extract were able to increase the diagnostic accuracy in detecting egg...

Note: Time-gated 3D single quantum dot tracking with simultaneous spinning disk imaging

Energy Technology Data Exchange (ETDEWEB)

DeVore, M. S.; Stich, D. G.; Keller, A. M.; Phipps, M. E.; Hollingsworth, J. A.; Goodwin, P. M.; Werner, J. H., E-mail: jwerner@lanl.gov [Center for Integrated Nanotechnologies, Los Alamos National Laboratory, Mail Stop G755, Los Alamos, New Mexico 87545 (United States); Cleyrat, C.; Lidke, D. S.; Wilson, B. S. [Department of Pathology and Cancer Research and Treatment Center, University of New Mexico, Albuquerque, New Mexico 87131 (United States)

2015-12-15

We describe recent upgrades to a 3D tracking microscope to include simultaneous Nipkow spinning disk imaging and time-gated single-particle tracking (SPT). Simultaneous 3D molecular tracking and spinning disk imaging enable the visualization of cellular structures and proteins around a given fluorescently labeled target molecule. The addition of photon time-gating to the SPT hardware improves signal to noise by discriminating against Raman scattering and short-lived fluorescence. In contrast to camera-based SPT, single-photon arrival times are recorded, enabling time-resolved spectroscopy (e.g., measurement of fluorescence lifetimes and photon correlations) to be performed during single molecule/particle tracking experiments.

Sensitisation to aeroallergens among asthmatic and non-asthmatic adolescents living in a poor region in the Northeast of Brazil.

Science.gov (United States)

Sarinho, E C S; Mariano, J; Sarinho, S W; Medeiros, D; Rizzo, J A; Almerinda R, S; Solé, D

2009-01-01

To assess the kind and frequency of sensitisation to aeroallergens (skin prick test - SPT) of asthmatic and non-asthmatic adolescents (13-14 years old) living in the city of Caruaru, Northeast of Brazil, and to analyse their exposure to some environmental factors. A case-control study was conducted with asthmatic (50) and non-asthmatic (150) adolescents diagnosed by the International Study of Asthma and Allergies in Childhood (ISAAC) written questionnaire. All were submitted to SPT with aeroallergens (house dust mites, cat and dog epithelium, cockroaches, moulds and grass) and completed a questionnaire to evaluate their environmental exposure. There were no significant differences between groups regarding gender, age, number of siblings and environmental exposure. Asthmatic subjects exhibited a higher frequency of positive SPTs than non-asthmatic subjects (54.0% vs 33.3%, p=0.009) mainly due to Periplaneta americana (34.0% vs 12.7%, p=0.0007 respectively) and Canis familiaris (20.0% vs 8.7%, p=0.029). Although sensitisation to aeroallergens was high among non-asthmatic adolescents, asthma was associated with parental history of atopic disease and sensitisation to P. americana and Canis familiaris but not to D. pteronyssinus showing that local studies are mandatory for the tailoring of appropriate management of allergic diseases.

RENDICIÓN DE CUENTAS HORIZONTAL Y PREPONDERANCIA PRESIDENCIAL: UNA COMBINACIÓN DIFÍCIL. EL CASO DE REPÚBLICA DOMINICANA, 1967-2009

Directory of Open Access Journals (Sweden)

Leiv MARSTEINTREDET

2010-01-01

Full Text Available Este artículo estudia la rendición de cuentas horizontal en República Dominicana. Primero se estudian las normas constitucionales que regulan el sistema de pesos y contrapesos. Aunque importantes, estas no explican la gran variación en niveles de rendición de cuentas observada en el caso dominicano. Por lo tanto, el trabajo se enfoca en el ejercicio de los gastos de los presupuestos nacionales y la situación financiera de las instituciones de control. El artículo sugiere analizar la situación presupuestaria de las instituciones fiscalizadoras y propone utilizar la desproporcionalidad entre el presupuesto aprobado y el ejecutado como un indicador del nivel de rendición de cuentas en un país. Un análisis multivariado de regresión de series de tiempo demuestra que la desproporcionalidad presupuestal aumenta con la preponderancia presidencial. Se concluye que, para el caso dominicano en el período 1967-2009, el comportamiento de varios presidentes más que otros factores es el que ha obstaculizado el funcionamiento del sistema de pesos y contrapesos. Por lo tanto, la experiencia dominicana confirma la hipótesis de O¿Donnell sobre las democracias delegativas.

Examination of near-wall hindered Brownian diffusion of nanoparticles: Experimental comparison to theories by Brenner (1961) and Goldman et al. (1967)

International Nuclear Information System (INIS)

Choi, C. K.; Margraves, C. H.; Kihm, K. D.

2007-01-01

Multilayered distributions of hindered mean square displacement (MSD) for nanoparticles are measured in the near-wall region within 500 nm from the solid surface using total internal reflection fluorescence microscopy, an evanescent wave microscopic imaging technique. Examined particles are yellow-green (505/515) polystyrene fluorescent nanospheres of 100, 250, and 500 nm radii with a specific gravity of 1.055. To ensure the measurement accuracy, special care is taken to minimize photobleaching of fluorescent particles by adding neutral density filters to optimally reduce the excitation power. The experimental results for parallel MSDs to the solid surface validate the theory of hindered diffusion [A. J. Goldman, R. G. Cox, and H. Brenner, 'Slow viscous motion of a sphere parallel to a plane - I: Motion through a quiescent fluid', Chem. Eng. Sci. 22, 637 (1967)] of spheres based on viscous slow-down in the near-wall region. It is also reported that the effect of adding sodium chloride up to 10 mM to the solution has little effect on the parallel diffusive motion of the tested nanoparticles. Experimental evidence shows that normal MSDs, for submicroscopic charged nanoparticles, are substantially different from Einstein's 2DΔt due to the deterministic motion arising from electrostatic forces

The Arabidopsis histone chaperone FACT is required for stress-induced expression of anthocyanin biosynthetic genes.

Science.gov (United States)

Pfab, Alexander; Breindl, Matthias; Grasser, Klaus D

2018-03-01

The histone chaperone FACT is involved in the expression of genes encoding anthocyanin biosynthetic enzymes also upon induction by moderate high-light and therefore contributes to the stress-induced plant pigmentation. The histone chaperone FACT consists of the SSRP1 and SPT16 proteins and associates with transcribing RNAPII (RNAPII) along the transcribed region of genes. FACT can promote transcriptional elongation by destabilising nucleosomes in the path of RNA polymerase II, thereby facilitating efficient transcription of chromatin templates. Transcript profiling of Arabidopsis plants depleted in SSRP1 or SPT16 demonstrates that only a small subset of genes is differentially expressed relative to wild type. The majority of these genes is either up- or down-regulated in both the ssrp1 and spt16 plants. Among the down-regulated genes, those encoding enzymes of the biosynthetic pathway of the plant secondary metabolites termed anthocyanins (but not regulators of the pathway) are overrepresented. Upon exposure to moderate high-light stress several of these genes are up-regulated to a lesser extent in ssrp1/spt16 compared to wild type plants, and accordingly the mutant plants accumulate lower amounts of anthocyanin pigments. Moreover, the expression of SSRP1 and SPT16 is induced under these conditions. Therefore, our findings indicate that FACT is a novel factor required for the accumulation of anthocyanins in response to light-induction.

Comparison of energy measurements in the standard penetration test using the cathead and rope method. Phases I and II. Final report

International Nuclear Information System (INIS)

Kovacs, W.D.; Salomone, L.A.; Yokel, F.Y.

1983-11-01

Studies conducted on the Standard Penetration Test (SPT) and its present use in engineering practice show that a wide variation in the use of different pieces of SPT equipment, procedures and personnel results in a range of energy measured in the drill rods from 30 to 85 percent of the standard SPT energy. The potential energy and kinetic energy of the hammer were measured prior to impact, and the energy passing through the drill rods was calculated from a force-time measurement in the rods. It was found that safety (type) hammers tend to allow more kinetic energy to pass through the hammer-anvil system than donut (type) hammers. The energy passing through the drill rods was calculated by using a digital processing oscilloscope and an SPT Calibrator. Lessons learned in evaluating the energy measurement by these two methods are discussed. The combined effect of the drill rig used, the operator and his procedures, and the SPT equipment should be considered when energy is to be evaluated. The variation of average energy ratio within various drill rig models was found to be about as large as that among drill rig models. It was therefore impossible to make a statistically significant estimate of the reference energy which is representative of the average energy delivered in the US practice. 29 references, 24 figures, 20 tables

The prevalence of food allergy in infants in Chongqing, China.

Science.gov (United States)

Chen, Jing; Hu, Yan; Allen, Katrina J; Ho, Marco H K; Li, Haiqi

2011-06-01

Over the past three decades, the prevalence of allergic diseases has markedly increased in developed countries. There has been a paucity of data on food allergy (FA) in developing countries such as China. We aimed to estimate the prevalence and the clinical features of FA in Chinese infants attending a routine well-baby clinic in Chongqing, China. From January 1st to February 28th, 2009, consecutive infants and young children aged 0-12 months attending routine well-baby checks at the Department of Primary Child Care, Children's Hospital of Chongqing Medical University, were invited to participate in the study. Parents completed questionnaires, and children were skin prick tested (SPT) to a panel of 10 foods (egg white, egg yolk, cow's milk, soybean, peanut, wheat, fish, shrimp, orange, and carrot) together of histamine and saline controls. Subjects with either a positive SPT or a positive medical history were invited to undergo an oral food challenge. Of 497 children who consented to participate, 477 (96%) participated fully in the study. Of these, 56 subjects had a positive SPT (11.3%), with 45 positive to egg, 13 to cow's milk, 2 to peanut, 1 to fish, shrimp, and orange respectively. Eighty subjects (16.1%, 80/497) participated in food challenges.   The overall prevalence of challenge-proven FA in 0- to 1-yr-old children in Chongqing, China, was 3.8% (18/477, 95% CI, 2.5-5.9%) with 2.5% (12/477) egg allergic and 1.3% (6/477) cow's milk allergic. © 2011 John Wiley & Sons A/S.

Cow's Milk Desensitization in Anaphylactic Patients: A New Personalized-dose Method.

Science.gov (United States)

Babaie, Delara; Nabavi, Mohammad; Arshi, Saba; Mesdaghi, Mehrnaz; Chavoshzadeh, Zahra; Bemanian, Mohammad Hasan; Tafakori, Mitra; Amirmoini, Mehrdad; Esmailzadeh, Hosein; Molatefi, Rasoul; Rekabi, Mahsa; Akbarpour, Nadieh; Masoumi, Farimah; Fallahpour, Morteza

2017-02-01

Cow's milk allergy (CMA) is the most frequent food allergy in children and oral immunotherapy (OIT) is a promising approach for treatment of patients. The most challenging cases are anaphylactic with coexisting asthma and proposing safe protocols is crucial especially in high risk groups. Considering that CMA varies among patients, an individualized OIT protocol would be beneficial to achieve a safer and more efficient method of desensitization. 18 children more than 3 years of age with IgE-mediated CMA were enrolled. CMA was confirmed by positive skin prick test (SPT) and positive oral food challenge (OFC) and 60% of individuals had a convincing history of persistent asthma. SPT with milk extracts, whole fresh milk and serially diluted milk concentrations were performed.  The dilution of milk that induced 3-5 mm of wheal in each individual was selected as the starting dilution for OIT. Desensitization began by 1 drop of the defined dilution and continued increasingly. Overall, 16 out of 18 children (88.8%) achieved the daily intake of 120 mL of milk. Four out of these 16 children accomplished the protocol without any adverse allergic reactions. 12 patients experienced mild to severe reactions. Wheal and erythema in SPT (p≤0.001), and sIgE (p≤0.003) to most milk allergens were significantly decreased following desensitization. We successfully desensitized 16 of 18 children with IgE-mediated CMA by individualized desensitization protocol. Individualizing the OIT protocol would be helpful to save time and perhaps to relieve the allergic symptoms after ingesting cow's milk intake.

Public views of health insurance in Japan during the era of attaining universal health coverage: a secondary analysis of an opinion poll on health insurance in 1967

Directory of Open Access Journals (Sweden)

Ikuma Nozaki

2017-07-01

Full Text Available While Japan’s success in achieving universal health insurance over a short period with controlled healthcare costs has been studied from various perspectives, that of beneficiaries have been overlooked. We conducted a secondary analysis of an opinion poll on health insurance in 1967, immediately after reaching universal coverage. We found that people continued to face a slight barrier to healthcare access (26.8% felt medical expenses were a heavy burden and had high expectations for health insurance (60.5% were satisfied with insured medical services and 82.4% were willing to pay a premium. In our study, younger age, having children before school age, lower living standards, and the health insurance scheme were factors that were associated with a willingness to pay premiums. Involving high-income groups in public insurance is considered to be the key to ensuring universal coverage of social insurance.

Skin prick test results in patients with atopic symptoms in Yozgat district

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Emine Çölgeçen

2014-03-01

Full Text Available Objective: Skin prick test (SPT is used widely and fastly to determine the allergens in atopic disease. We aimed in this study to analysis the relationship between total serum IgE (T.IgE and allergens that found by SPT and looking over the frequency of allergens. Methods: We evaluated clinical findings and SPT results and T.IgE levels of 190 patients who admitted to dermatology outpatient clinic, retrospectively. Rsults: 53 (27.9% patients had idiopathic generalized pruritus (IGP, 41 (21.6% had atopic dermatitis (AD, 40 (21.1% had chronic idiopathic urticaria (CIU, 38 (20% had allergic rhinitis (AR, and 18 (9.5% had allergic asthma (AA. 123 (64.7% patients had positive reaction to at least one or more allergen on SPT. Of these patients 28 were IGP, 30 were AD, 20 were CIU, 28 were AR, and 17 were AA. The most common allergens were pine pollen (25.3%, wheat pollen (18.4%, and dog epithelium (15.8%. The mean levels of T.IgE was 382.61 ± 517.28 IU/ml (1-2500. T.IgE is higher 54.9% of patients. It was seen that DPT positivity was significantly more frequent in patients with increased T.IgE levels than those with normal total serum IgE level (p<0.05. Conclusion: We think that pine tree and wheat pollens are the most commonly encountered allergens at Yozgat area. Moreover, our findings indicated to the requirement and benefits of DPT in patients with AD, AR and AA in addition to the those KİU and İJP, particularly in patients with increased T.IgE levels, although further studies with larger sample size are needed. J Clin Exp Invest 2014; 5 (1: 64-68

Yeast Interacting Proteins Database: YOR358W, YOR047C [Yeast Interacting Proteins Database

Lifescience Database Archive (English)

Full Text Available ; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; act...rotein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator o

Physical Fitness of Girls Practising Acrobatic and Trampoline Gymnastics Compared to that of Girls Practising other Sports in the Subcarpathian Province Team

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Seredyński Antoni

2015-09-01

Full Text Available Introduction. The aim of this study was to determine the level of overall physical fitness of girls from the Subcarpathian Province Team (SPT who practise acrobatic and trampoline gymnastics and compare it to that of other members of the SPT. A comparative analysis of the subjects’ physique was also performed.

The prevalence of peanut sensitization and the association to pollen sensitization in a cohort of unselected adolescents

DEFF Research Database (Denmark)

Mørtz, Charlotte G; Andersen, Klaus Ejner; Bindslev-Jensen, Carsten

2005-01-01

In the last decade an increased occurrence of peanut hypersensitivity and severe anaphylactic reactions to peanut have been reported. However, few prevalence studies have been performed in unselected populations. This study evaluated the point prevalence of peanut hypersensitivity in Danish...... adolescents. The point prevalence of peanut allergy confirmed by oral challenge was estimated to 0.5%. The number of adolescents sensitized to peanut by specific immunoglobulin E (IgE) (CAP FEIA) and skin prick test (SPT) were higher (5.8% resp. 3.4%). In adolescents without clinically relevant peanut...... sensitization most cases were sensitized to grass pollen and the IgE class for grass was higher than for peanut. A correlation between peanut and pollen (grass) sensitization is therefore plausible. Before a positive SPT or specific IgE measurement to peanut is considered clinically relevant in a patient...

B-2 Extremely High Frequency SATCOM and Computer Increment 1 (B-2 EHF Inc 1)

Science.gov (United States)

2015-12-01

Confidence Level Confidence Level of cost estimate for current APB: 55% This APB reflects cost and funding data based on the B-2 EHF Increment I SCP...This cost estimate was quantified at the Mean (~55%) confidence level . Total Quantity Quantity SAR Baseline Production Estimate Current APB...Production Estimate Econ Qty Sch Eng Est Oth Spt Total 33.624 -0.350 1.381 0.375 0.000 -6.075 0.000 -0.620 -5.289 28.335 Current SAR Baseline to Current

Improving the Effectiveness of Penicillin Allergy De-labeling.

Science.gov (United States)

Bourke, Jack; Pavlos, Rebecca; James, Ian; Phillips, Elizabeth

2015-01-01

Approximately 10-20% of hospitalized patients are labeled as penicillin allergic, and this is associated with significant health and economic costs. We looked at the effectiveness of penicillin allergy de-labeling in clinical practice with the aim of deriving risk stratification models to guide testing strategies. Consecutive patients aged 15 years or more, referred to a Western Australian public hospital drug allergy service between 2008 and 2013 for beta-lactam allergy, were included. Follow-up surveys were conducted. Results of skin prick testing and intradermal testing (SPT/IDT) and oral challenge (OC), and follow-up of post testing antibiotic usage were the main outcomes. SPT/IDT was performed in 401 consecutive patients with immediate (IMM) (≤ 1 hour) (n = 151) and nonimmediate (NIM) (>1 hour) (n = 250) reactions. Of 341 patients, 42 (12.3%) were SPT/IDT+ to ≥ 1 penicillin reagents, including 35/114 (30.4%) in the IMM group and 7/227 (3.1%) in the NIM group (P penicillin VK (SPT/IDT negative predictive value [NPV] 99.2%). Selective or unrestricted beta-lactam was recommended in almost 90% overall, including 238/250 (95.2%) in the NIM group and 126/151 (83.4%) in the IMM group (P = .0001). Of 182 patients, 137 (75.3%) were following the allergy label modifications (ALM) at the time of follow-up. Penicillin SPT/IDT/OC safely de-labels penicillin-allergic patients and identifies selective beta-lactam allergies; however, incomplete adherence to ALM recommendations impairs effectiveness. Infrequent SPT/IDT+ and absent OC reactions in patients with NIM reactions suggest OC alone to be a safe and cost-effective de-labeling strategy that could improve the coverage of penicillin allergy de-labeling in lower risk populations. Copyright © 2015 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Observation of symmetry-protected topological band with ultracold fermions

Science.gov (United States)

Song, Bo; Zhang, Long; He, Chengdong; Poon, Ting Fung Jeffrey; Hajiyev, Elnur; Zhang, Shanchao; Liu, Xiong-Jun; Jo, Gyu-Boong

2018-01-01

Symmetry plays a fundamental role in understanding complex quantum matter, particularly in classifying topological quantum phases, which have attracted great interests in the recent decade. An outstanding example is the time-reversal invariant topological insulator, a symmetry-protected topological (SPT) phase in the symplectic class of the Altland-Zirnbauer classification. We report the observation for ultracold atoms of a noninteracting SPT band in a one-dimensional optical lattice and study quench dynamics between topologically distinct regimes. The observed SPT band can be protected by a magnetic group and a nonlocal chiral symmetry, with the band topology being measured via Bloch states at symmetric momenta. The topology also resides in far-from-equilibrium spin dynamics, which are predicted and observed in experiment to exhibit qualitatively distinct behaviors in quenching to trivial and nontrivial regimes, revealing two fundamental types of spin-relaxation dynamics related to bulk topology. This work opens the way to expanding the scope of SPT physics with ultracold atoms and studying nonequilibrium quantum dynamics in these exotic systems. PMID:29492457

Floquet Symmetry-Protected Topological Phases in Cold-Atom Systems

Science.gov (United States)

Potirniche, I.-D.; Potter, A. C.; Schleier-Smith, M.; Vishwanath, A.; Yao, N. Y.

2017-09-01

We propose and analyze two distinct routes toward realizing interacting symmetry-protected topological (SPT) phases via periodic driving. First, we demonstrate that a driven transverse-field Ising model can be used to engineer complex interactions which enable the emulation of an equilibrium SPT phase. This phase remains stable only within a parametric time scale controlled by the driving frequency, beyond which its topological features break down. To overcome this issue, we consider an alternate route based upon realizing an intrinsically Floquet SPT phase that does not have any equilibrium analog. In both cases, we show that disorder, leading to many-body localization, prevents runaway heating and enables the observation of coherent quantum dynamics at high energy densities. Furthermore, we clarify the distinction between the equilibrium and Floquet SPT phases by identifying a unique micromotion-based entanglement spectrum signature of the latter. Finally, we propose a unifying implementation in a one-dimensional chain of Rydberg-dressed atoms and show that protected edge modes are observable on realistic experimental time scales.

Floquet Symmetry-Protected Topological Phases in Cold-Atom Systems.

Science.gov (United States)

Potirniche, I-D; Potter, A C; Schleier-Smith, M; Vishwanath, A; Yao, N Y

2017-09-22

We propose and analyze two distinct routes toward realizing interacting symmetry-protected topological (SPT) phases via periodic driving. First, we demonstrate that a driven transverse-field Ising model can be used to engineer complex interactions which enable the emulation of an equilibrium SPT phase. This phase remains stable only within a parametric time scale controlled by the driving frequency, beyond which its topological features break down. To overcome this issue, we consider an alternate route based upon realizing an intrinsically Floquet SPT phase that does not have any equilibrium analog. In both cases, we show that disorder, leading to many-body localization, prevents runaway heating and enables the observation of coherent quantum dynamics at high energy densities. Furthermore, we clarify the distinction between the equilibrium and Floquet SPT phases by identifying a unique micromotion-based entanglement spectrum signature of the latter. Finally, we propose a unifying implementation in a one-dimensional chain of Rydberg-dressed atoms and show that protected edge modes are observable on realistic experimental time scales.

Als Clinicus over de Grenzen van de Psychiatrie. De verwantschap tussen literatuur en wetenschap in het werk van de psychiater H.C. Rümke (1893-1967

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Ingrid Kloosterman

2010-09-01

Full Text Available As a clincian beyond the boundaries of psychiatry. The congeniality of literature and psychiatry in the work of psychiatrist H.C. Rümke (1893-1967 One of the most important Dutch psychiatrists in the interwar period was H.C. Rümke (1893-1967. With his eclectic interest in psychiatric approaches such as both psychoanalysis and phenomenology, Rümke is most well known for his remarkable diagnostic and therapeutic skills. The life and work of Rümke has been studied in detail, most notably by the Dutch historian Jacob Van Belzen. Despite this extensive research, in this paper it is stated that a relevant aspect of Rümke’s work has been largely disregarded – namely his profound interest in and use of poetry and literature. Not only did Rümke write poems himself under the pseudonym of H. Cornelius, in his scholarly work he frequently refers to fictional literature and at the end of his career he wrote a comprehensive analysis of Frederik van Eeden’s novel Van de Koele Meeren des Doods. For the eclectic clinician Rümke literature and poetry are a source of knowledge to gain insight into the human psyche. Furthermore, according to Rümke, often literature succeeds better at expressing the human condition than the science of psychiatry can. In this article it is argued that for a coherent interpretation of the life and work of Rümke this literal and poetic aspect of his work cannot be disregarded. It is precisely Rümke’s profound interest in literature and poetry that reflects his two main theses about the science of psychiatry. These are on the one hand the centrality of clinical practice and on the other hand the boundaries of psychiatry. As a clinical practitioner Rümke’s aim was to be able to understand the suffering of the patient – literature and poetry could help him do that. Rümke’s use of literature and poetry can be understood by taking into account the context of the clinic, but the intertwinement between psychiatry

IgE Sensitization Patterns to Commonly Consumed Foods Determined by Skin Prick Test in Korean Adults.

Science.gov (United States)

Kim, Sung Ryeol; Park, Hye Jung; Park, Kyung Hee; Lee, Jae-Hyun; Park, Jung-Won

2016-08-01

Offending food allergens can vary with regional preferences in food consumption. In this study, we analysed sensitization rates to commonly consumed foods in Korean adults suspected of having food allergy. One hundred and thirty four subjects underwent a skin prick test (SPT) with 55 food allergens, of which 13 were made by our laboratory and the rest were commercially purchased. Of the 134 patients, 73 (54.5%) were sensitized to one or more food allergens. Sensitization to chrysalis was detected most frequently, at a rate of 25.4%. Sensitization rates to other food allergens were as follows: maize grain (13.4%), shrimp (11.9%), almond (11.1%), wheat flour (8.2%), lobster (8.2%), buckwheat (8.2%), mackerel (5.2%), pollack (5.2%), halibut (4.5%), peanut (4.5%), anchovy (4.4%), squid (3.7%), saury (3.0%), common eel (3.0%), yellow corvina (3.0%), hairtail (2.2%), octopus (2.2%), and others. In addition to well-known food allergens, sensitivity to mackerel, chrysalis, pollack, and halibut, which are popular foods in Korea, was observed at high rates in Korean adults. We suggest that the SPT panel for food allergy in Korea should include these allergens.

IgE Sensitization Patterns to Commonly Consumed Foods Determined by Skin Prick Test in Korean Adults

Science.gov (United States)

2016-01-01

Offending food allergens can vary with regional preferences in food consumption. In this study, we analysed sensitization rates to commonly consumed foods in Korean adults suspected of having food allergy. One hundred and thirty four subjects underwent a skin prick test (SPT) with 55 food allergens, of which 13 were made by our laboratory and the rest were commercially purchased. Of the 134 patients, 73 (54.5%) were sensitized to one or more food allergens. Sensitization to chrysalis was detected most frequently, at a rate of 25.4%. Sensitization rates to other food allergens were as follows: maize grain (13.4%), shrimp (11.9%), almond (11.1%), wheat flour (8.2%), lobster (8.2%), buckwheat (8.2%), mackerel (5.2%), pollack (5.2%), halibut (4.5%), peanut (4.5%), anchovy (4.4%), squid (3.7%), saury (3.0%), common eel (3.0%), yellow corvina (3.0%), hairtail (2.2%), octopus (2.2%), and others. In addition to well-known food allergens, sensitivity to mackerel, chrysalis, pollack, and halibut, which are popular foods in Korea, was observed at high rates in Korean adults. We suggest that the SPT panel for food allergy in Korea should include these allergens. PMID:27478328

strength characterization of foundation soils at federal university ...

African Journals Online (AJOL)

HOD

used to calculate bearing capacity factors for structural footings [1]. One of in situ testing methods is the. Standard Penetration Test (SPT) that is used to identify soil type and stratigraphy along with being a relative measure of strength [2]. In this study, the SPT blow count was used as a parameter for in situ characterization of.

Analysis and computer program for rupture-risk prediction of abdominal aortic aneurysms

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Li Zhonghua

2006-03-01

Full Text Available Abstract Background Ruptured abdominal aortic aneurysms (AAAs are the 13th leading cause of death in the United States. While AAA rupture may occur without significant warning, its risk assessment is generally based on critical values of the maximum AAA diameter (>5 cm and AAA-growth rate (>0.5 cm/year. These criteria may be insufficient for reliable AAA-rupture risk assessment especially when predicting possible rupture of smaller AAAs. Methods Based on clinical evidence, eight biomechanical factors with associated weighting coefficients were determined and summed up in terms of a dimensionless, time-dependent severity parameter, SP(t. The most important factor is the maximum wall stress for which a semi-empirical correlation has been developed. Results The patient-specific SP(t indicates the risk level of AAA rupture and provides a threshold value when surgical intervention becomes necessary. The severity parameter was validated with four clinical cases and its application is demonstrated for two AAA cases. Conclusion As part of computational AAA-risk assessment and medical management, a patient-specific severity parameter 0

EA 18G Growler Aircraft (EA 18G)

Science.gov (United States)

2015-12-01

10051.9 N/A 13186.9 8636.4 11550.1 15672.4 1 APB Breach Confidence Level Confidence Level of cost estimate for current APB: 50% The current...estimate recommendation aims to provide sufficient resources to execute the program under normal conditions, encountering average levels of technical...TY $M) Initial PAUC Development Estimate Changes PAUC Production Estimate Econ Qty Sch Eng Est Oth Spt Total 93.573 4.150 1.442 -0.319 0.947 -0.348

Antitumor activity of a novel and orally available inhibitor of serine palmitoyltransferase

International Nuclear Information System (INIS)

Yaguchi, Masahiro; Shibata, Sachio; Satomi, Yoshinori; Hirayama, Megumi; Adachi, Ryutaro; Asano, Yasutomi; Kojima, Takuto; Hirata, Yasuhiro; Mizutani, Akio; Kiba, Atsushi; Sagiya, Yoji

2017-01-01

Metabolic reprogramming is an essential hallmark of neoplasia. Therefore, targeting cancer metabolism, including lipid synthesis, has attracted much interest in recent years. Serine palmitoyltransferase (SPT) plays a key role in the initial and rate-limiting step of de novo sphingolipid biosynthesis, and inhibiting SPT activity prevents the proliferation of certain cancer cells. Here, we identified a novel and orally available SPT inhibitor, compound-2. Compound-2 showed an anti-proliferative effect in several cancer cell models, reducing the levels of the sphingolipids ceramide and sphingomyelin. In the presence of compound-2, exogenously added S1P partially compensated the intracellular sphingolipid levels through the salvage pathway by partially rescuing compound-2-induced cytotoxicity. This suggested that the mechanism underlying the anti-proliferative effect of compound-2 involved the reduction of sphingolipid levels. Indeed, compound-2 promoted multinuclear formation with reduced endogenous sphingomyelin levels specifically in a compound-2-sensitive cell line, indicating that the effect was induced by sphingolipid reduction. Furthermore, compound-2 showed potent antitumor activity without causing significant body weight loss in the PL-21 acute myeloid leukemia mouse xenograft model. Therefore, SPT may be an attractive therapeutic anti-cancer drug target for which compound-2 may be a promising new drug. - Highlights: • We discovered compound-2, a novel and orally available SPT inhibitor. • Compound-2 was cytotoxic against PL-21 acute myeloid leukemia cells. • Compound-2 showed antitumor activity in the PL-21 mouse xenograft model.

A Itinerância dos artistas: a construção do campo das artes visuais em Brasília (1958-1967 The itinerancy of artists: the construction of the visual arts field in Brasília (1958-1967

Directory of Open Access Journals (Sweden)

Angélica Madeira

2002-10-01

Full Text Available Este artigo apresenta os primeiros resultados do projeto Itinerâncias Urbanas: os artistas e o campo das representações estéticas, que pretende mapear e analisar a produção e a consolidação do campo das artes visuais em Brasília, em três momentos significativos de sua história: os anos 50, quando se tornaram hegemônicos o paradigma racionalista em arquitetura e urbanismo, e o concretismo no Brasil; 1967, ano do quarto Salão Nacional de Artes Plásticas de Brasília, o último promovido pelo mecenato oficial, que tornou explícita a tendência conceitual na arte brasileira; e, finalmente o momento contemporâneo, ou seja, as duas últimas décadas, quando mudam os mecanismos de patrocínio e se torna mais explícita a relação entre arte e mercado. O artigo pretende ainda pontuar algumas questões mais substantivas, de natureza teórica, assim como alguns impasses de método.This article presents the first results of a research which aims at mapping and analyzing the construction and the consolidation of the field of the visual arts in Brasília. The whole project is divided into three significant moments of the city's history: the fifties, when the rationalist model in architecture and urban design, and concretism in the field of the arts became hegemonic; the late sixties, when conceptualism was strongly affirmed on the Brazilian art scene; and finally, the two last decades, which brought big changes to patronage and to art market strategies. The article also punctuate some theoretical and methodological remarks.

A measurement of gravitational lensing of the cosmic microwave background by galaxy clusters using data from the south pole telescope

Energy Technology Data Exchange (ETDEWEB)

Baxter, E. J.; Keisler, R.; Dodelson, S.; Aird, K. A.; Allen, S. W.; Ashby, M. L. N.; Bautz, M.; Bayliss, M.; Benson, B. A.; Bleem, L. E.; Bocquet, S.; Brodwin, M.; Carlstrom, J. E.; Chang, C. L.; Chiu, I.; Cho, H-M.; Clocchiatti, A.; Crawford, T. M.; Crites, A. T.; Desai, S.; Dietrich, J. P.; de Haan, T.; Dobbs, M. A.; Foley, R. J.; Forman, W. R.; George, E. M.; Gladders, M. D.; Gonzalez, A. H.; Halverson, N. W.; Harrington, N. L.; Hennig, C.; Hoekstra, H.; Holder, G. P.; Holzapfel, W. L.; Hou, Z.; Hrubes, J. D.; Jones, C.; Knox, L.; Lee, A. T.; Leitch, E. M.; Liu, J.; Lueker, M.; Luong-Van, D.; Mantz, A.; Marrone, D. P.; McDonald, M.; McMahon, J. J.; Meyer, S. S.; Millea, M.; Mocanu, L. M.; Murray, S. S.; Padin, S.; Pryke, C.; Reichardt, C. L.; Rest, A.; Ruhl, J. E.; Saliwanchik, B. R.; Saro, A.; Sayre, J. T.; Schaffer, K. K.; Shirokoff, E.; Song, J.; Spieler, H. G.; Stalder, B.; Stanford, S. A.; Staniszewski, Z.; Stark, A. A.; Story, K. T.; van Engelen, A.; Vanderlinde, K.; Vieira, J. D.; Vikhlinin, A.; Williamson, R.; Zahn, O.; Zenteno, A.

2015-06-20

Clusters of galaxies are expected to gravitationally lens the cosmic microwave background (CMB) and thereby generate a distinct signal in the CMB on arcminute scales. Measurements of this effect can be used to constrain the masses of galaxy clusters with CMB data alone. Here we present a measurement of lensing of the CMB by galaxy clusters using data from the South Pole Telescope (SPT). We develop a maximum likelihood approach to extract the CMB cluster lensing signal and validate the method on mock data. We quantify the effects on our analysis of several potential sources of systematic error and find that they generally act to reduce the best-fit cluster mass. It is estimated that this bias to lower cluster mass is roughly 0.85σ in units of the statistical error bar, although this estimate should be viewed as an upper limit. We apply our maximum likelihood technique to 513 clusters selected via their Sunyaev–Zeldovich (SZ) signatures in SPT data, and rule out the null hypothesis of no lensing at 3.1σ. The lensing-derived mass estimate for the full cluster sample is consistent with that inferred from the SZ flux: ${M}_{200,\\mathrm{lens}}={0.83}_{-0.37}^{+0.38}\\;{M}_{200,\\mathrm{SZ}}$ (68% C.L., statistical error only).

Polybrominated diphenyl ethers (PBDEs) and their methoxylated derivatives in pike from Swedish waters with emphasis on temporal trends, 1967-2000.

Science.gov (United States)

Kierkegaard, A; Bignert, A; Sellström, U; Olsson, M; Asplund, L; Jansson, B; De Wit, C A

2004-07-01

Temporal trends of five tetra- to hexabromodiphenyl ethers [BDE47, BDE99, BDE100, BDE153 and BDE154) and two methoxy-tetraBDEs [6-methoxy-2,2',4,4'- tetraBDE (6-MeO-BDE47) and 2'-methoxy-2,3',4,5'- tetraBDE (2'-MeO-BDE68)] in pike from Lake Bolmen for the years 1967-2000, are presented. All BDE congeners show increasing trends up to the mid-1980s (Sigma5PBDE from 60 to 1600 pg/g wet weight in 1989, i.e. a more than 25-fold increase), and then decrease or level off. The decreasing trends of PBDEs after the 1980s were considerably slower in the present study than was found in a study of an environmental matrix from the Baltic Proper covering the same time period. This difference suggests local sources near Lake Bolmen. The MeO-BDEs show initially decreasing concentrations, which for 6-MeO-BDE47 continues until the early 1990s. The concentrations of 6-MeO-BDE47 in herring from five locations along the Swedish coast increased from south to north in the Baltic Sea. No correlation between the concentrations of the BDE congeners and the MeO-BDEs was observed, indicating sources other than PBDEs for these compounds. The presence of MeO-BDEs in fish from lakes with different characteristics suggests a natural production not favoured by eutrophication, or dependent on sampling season and geographical location.

The diagnostic accuracy of the atopy patch test in diagnosing hypersensitivity to cow's milk and hen's egg in unselected children with and without atopic dermatitis

DEFF Research Database (Denmark)

Osterballe, Morten; Andersen, Klaus E; Bindslev-Jensen, Carsten

2004-01-01

BACKGROUND: Previous studies have suggested that the atopy patch test (APT) may make oral challenge superfluous in diagnosing children with food hypersensitivity. OBJECTIVE: To investigate the clinical relevance of APT in predicting hypersensitivity to cow's milk and hen's egg in 486 unselected...... children 3 years of age. METHOD: The children were examined by APT, skin prick (SPT), histamine release (HR), and specific IgE followed by oral challenge when hypersensitivity to cow's milk or hen's egg was suspected. RESULTS: Food hypersensitivity confirmed by oral challenge was 1.6% to hen's egg and 0.......6% to cow's milk. No hypersensitivity to cow's milk or hen's egg was predicted by APT alone. CONCLUSION: APT could not predict food hypersensitivity not predicted by SPT, HR, or specific IgE. Thus, APT cannot be recommended in daily practice for the diagnosis of hypersensitivity to cow's milk and hen's egg...

Juventud rebelde, campesinado indígena y la instalación del discurso de clases en los campos de Cautín. Movimiento Campesino Revolucionario. Chile, 1967-1973

Directory of Open Access Journals (Sweden)

Ovidio Cárcamo Hernández

2015-06-01

Full Text Available El propósito de este artículo es analizar el itinerario seguido por algunos militantes del Movimiento de Izquierda Revolucionaria (MIR, en el marco de la Reforma Agraria chilena entre 1967 y 1973, en la provincia de Cautín, en el surde Chile. Además buscamos describir el proceso de vinculación entre los militantes del MIR y el campesinado indígena, relación de la cual nació el Movimiento Campesino Revolucionario (MCR a fines de 1970, iniciándose así una importante embestida contra la gran propiedad agraria, que puso en jaque a los grupos patronales locales, por lo menos hasta el Golpe Militar de 1973. Por otra parte, hemos buscado caracterizar a aquellos jóvenes, mayoritariamente de la clase media urbana, cuya entrega permitió al MIR crear un frente de masas, poco común en la historia agraria de Chile.

Field-theory representation of gauge-gravity symmetry-protected topological invariants, group cohomology, and beyond.

Science.gov (United States)

Wang, Juven C; Gu, Zheng-Cheng; Wen, Xiao-Gang

2015-01-23

The challenge of identifying symmetry-protected topological states (SPTs) is due to their lack of symmetry-breaking order parameters and intrinsic topological orders. For this reason, it is impossible to formulate SPTs under Ginzburg-Landau theory or probe SPTs via fractionalized bulk excitations and topology-dependent ground state degeneracy. However, the partition functions from path integrals with various symmetry twists are universal SPT invariants, fully characterizing SPTs. In this work, we use gauge fields to represent those symmetry twists in closed spacetimes of any dimensionality and arbitrary topology. This allows us to express the SPT invariants in terms of continuum field theory. We show that SPT invariants of pure gauge actions describe the SPTs predicted by group cohomology, while the mixed gauge-gravity actions describe the beyond-group-cohomology SPTs. We find new examples of mixed gauge-gravity actions for U(1) SPTs in (4+1)D via the gravitational Chern-Simons term. Field theory representations of SPT invariants not only serve as tools for classifying SPTs, but also guide us in designing physical probes for them. In addition, our field theory representations are independently powerful for studying group cohomology within the mathematical context.

Effects of late defoliations on chemical and sensory characteristics of cv. uva longanesi wines

OpenAIRE

Tessarin, P; Boliani, A. C; Botelho, R. V; Rusin, C; Versari, A; Parpinello, G. P; Rombolà, A. D

2014-01-01

In this study we investigated the effects of late leaf removal on the berry and wine composition and on wine sensory characteristics of Uva Longanesi, a late maturing red Italian grape variety, which wines are characterized by high levels of alcohol and excessive astringency, the latter apparently intensified by late defoliation practices. During 2008 season, spur-pruned trained vines were submitted to manual defoliation (4 basal leaves) at the onset (DEF I, 210 DOY) or at the end (DEF II, 23...

A systematic comparison of all mutations in hereditary sensory neuropathy type I (HSAN I) reveals that the G387A mutation is not disease associated.

Science.gov (United States)

Hornemann, Thorsten; Penno, Anke; Richard, Stephane; Nicholson, Garth; van Dijk, Fleur S; Rotthier, Annelies; Timmerman, Vincent; von Eckardstein, Arnold

2009-04-01

Hereditary sensory neuropathy type 1 (HSAN I) is an autosomal dominant inherited neurodegenerative disorder of the peripheral nervous system associated with mutations in the SPTLC1 subunit of the serine palmitoyltransferase (SPT). Four missense mutations (C133W, C133Y, V144D and G387A) in SPTLC1 were reported to cause HSAN I. SPT catalyses the condensation of Serine and Palmitoyl-CoA, which is the first and rate-limiting step in the de novo synthesis of ceramides. Earlier studies showed that C133W and C133Y mutants have a reduced activity, whereas the impact of the V144D and G387A mutations on the human enzyme was not tested yet. In this paper, we show that none of the HSAN I mutations interferes with SPT complex formation. We demonstrate that also V144D has a reduced SPT activity, however to a lower extent than C133W and C133Y. In contrast, the G387A mutation showed no influence on SPT activity. Furthermore, the growth phenotype of LY-B cells--a SPTLC1 deficient CHO cell line--could be reversed by expressing either the wild-type SPTLC1 or the G387A mutant, but not the C133W mutant. This indicates that the G387A mutation is most likely not directly associated with HSAN I. These findings were genetically confirmed by the identification of a nuclear HSAN family which showed segregation of the G387A variant as a non-synonymous SNP.

Evaluation of basophil activation test in suspected food hypersensitivity.

Science.gov (United States)

Pignatti, Patrizia; Yacoub, Mona-Rita; Testoni, Claudia; Pala, Gianni; Corsetti, Maura; Colombo, Giselda; Meriggi, Antonio; Moscato, Gianna

2017-07-01

Food hypersensitivity is characterized by a wide range of symptoms. The relationship between symptoms and food is more frequently suspected than objectively proven. Basophil activation test (BAT) is based on the evaluation of activation markers on blood basophils in vitro stimulated with drugs or allergens. The aim of the study was to evaluate the usefulness of BAT when introduced in the routine work-up of suspected food hypersensitivity. BAT was requested in subjects with food adverse reactions when a discrepancy existed among history and skin prick test (SPT) and/or specific IgE. Data from 150 subjects were analysed using CD63 as basophil activation marker. Thirty controls were evaluated for cut-offs. Immunoblots was performed with the sera of representative subjects positive for BAT and negative for SPT and sIgE. 1,024 BAT were carried out, the agreement (positive/positive and negative/negative) was 78.5% for BAT vs. SPT and 78.3% for BAT vs. IgE. Atopic patients, but not atopic controls, more frequently had a positive BAT than non-atopic patients (P tested food) and both negative sIgE and SPT. Immunoblots revealed the presence of sIgE for the tested foods in representative patients with positive BAT, negative SPT and sIgE. Introduction of BAT in routine of food hypersensitivity, limited to subjects with a discrepancy between history and traditional tests, might be useful particularly when total IgE are low. © 2015 International Clinical Cytometry Society. © 2015 International Clinical Cytometry Society.

ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcription.

OpenAIRE

Marcus, G A; Horiuchi, J; Silverman, N; Guarente, L

1996-01-01

In this report we described the cloning and characterization of ADA5, a gene identified by resistance to GAL4-VP16-mediated toxicity. ADA5 binds directly to the VP16 activation domain but not to a transcriptionally defective VP16 double point mutant. Double mutants with mutations in ada5 and other genes (ada2 or ada3) isolated by resistance to GAL4-VP16 grow like ada5 single mutants, suggesting that ADA5 is in the same pathway as the other ADA genes. Further, ADA5 cofractionates and coprecipi...

The diagnosis of food allergy: a systematic review and meta-analysis.

Science.gov (United States)

Soares-Weiser, K; Takwoingi, Y; Panesar, S S; Muraro, A; Werfel, T; Hoffmann-Sommergruber, K; Roberts, G; Halken, S; Poulsen, L; van Ree, R; Vlieg-Boerstra, B J; Sheikh, A

2014-01-01

We investigated the accuracy of tests used to diagnose food allergy. Skin prick tests (SPT), specific-IgE (sIgE), component-resolved diagnosis and the atopy patch test (APT) were compared with the reference standard of double-blind placebo-controlled food challenge. Seven databases were searched and international experts were contacted. Two reviewers independently identified studies, extracted data, and used QUADAS-2 to assess risk of bias. Where possible, meta-analysis was undertaken. Twenty-four (2831 participants) studies were included. For cows' milk allergy, the pooled sensitivities were 53% (95% CI 33-72), 88% (95 % CI 76-94), and 87% (95% CI 75-94), and specificities were 88% (95% CI 76-95), 68% (95% CI 56-77), and 48% (95% CI 36-59) for APT, SPT, and sIgE, respectively. For egg, pooled sensitivities were 92% (95% CI 80-97) and 93% (95% CI 82-98), and specificities were 58% (95% CI 49-67) and 49% (40-58%) for skin prick tests and specific-IgE. For wheat, pooled sensitivities were 73% (95% CI 56-85) and 83% (95% CI 69-92), and specificities were 73% (95% CI 48-89) and 43% (95% CI 20-69%) for SPT and sIgE. For soy, pooled sensitivities were 55% (95% CI 33-75) and 83% (95% CI 64-93), and specificities were 68% (95% CI 52-80) and 38% (95% CI 24-54) for SPT and sIgE. For peanut, pooled sensitivities were 95% (95% CI 88-98) and 96% (95% CI 92-98), and specificities were 61% (95% CI 47-74), and 59% (95% CI 45-72) for SPT and sIgE. The evidence base is limited and weak and is therefore difficult to interpret. Overall, SPT and sIgE appear sensitive although not specific for diagnosing IgE-mediated food allergy. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The prevalence of positive reactions in the atopy patch test with aeroallergens and food allergens in subjects with atopic eczema: a European multicenter study.

Science.gov (United States)

Darsow, U; Laifaoui, J; Kerschenlohr, K; Wollenberg, A; Przybilla, B; Wüthrich, B; Borelli, S; Giusti, F; Seidenari, S; Drzimalla, K; Simon, D; Disch, R; Borelli, S; Devillers, A C A; Oranje, A P; De Raeve, L; Hachem, J-P; Dangoisse, C; Blondeel, A; Song, M; Breuer, K; Wulf, A; Werfel, T; Roul, S; Taieb, A; Bolhaar, S; Bruijnzeel-Koomen, C; Brönnimann, M; Braathen, L R; Didierlaurent, A; André, C; Ring, J

2004-12-01

The atopy patch test (APT) was proposed to evaluate IgE-mediated sensitizations in patients with atopic eczema (AE). The prevalence and agreement with clinical history and specific IgE (sIgE) of positive APT reactions was investigated in six European countries using a standardized method. A total of 314 patients with AE in remission were tested in 12 study centers on clinically uninvolved, non-abraded back skin with 200 index of reactivity (IR)/g of house dust mite Dermatophagoides pteronyssinus, cat dander, grass, and birch pollen allergen extracts with defined major allergen contents in petrolatum. Extracts of egg white, celery and wheat flour with defined protein content were also patch tested. APT values were evaluated at 24, 48, and 72 h according to the European Task Force on Atopic Dermatitis (ETFAD) guidelines. In addition, skin-prick test (SPT) and sIgE and a detailed history on allergen-induced eczema flares were obtained. Previous eczema flares, after contact with specific allergens, were reported in 1% (celery) to 34% (D. pteronyssinus) of patients. The frequency of clear-cut positive APT reactions ranged from 39% with D. pteronyssinus to 9% with celery. All ETFAD intensities occured after 48 and 72 h. Positive SPT (16-57%) and elevated sIgE (19-59%) results were more frequent. Clear-cut positive APT with all SPT and sIgE testing negative was seen in 7% of the patients, whereas a positive APT without SPT or sIgE for the respective allergen was seen in 17% of the patients. APT, SPT and sIgE results showed significant agreement with history for grass pollen and egg white (two-sided Pr > /Z/ atopic controls, no positive APT reaction was seen. Aeroallergens and food allergens are able to elicit eczematous skin reactions after epicutaneous application. As no gold standard for aeroallergen provocation in AE exists, the relevance of aeroallergens for AE flares may be evaluated by APT in addition to SPT and sIgE. The data may contribute to the international

Spray deposited CeO2–TiO2 counter electrode for electrochromic ...

Indian Academy of Sciences (India)

Abstract. Optically passive thin films of CeO2–TiO2 mixed oxides with molar ratio of Ce/Ti of 0.05 were deposited by the spray pyrolysis technique (SPT) on a glass and fluorine-doped tin oxide (FTO)-coated glass substrates. Precur- sor solution containing cerium nitrate hexahydrate (Ce(NO3)2·6H2O) and titanium ...

Gapless Symmetry-Protected Topological Order

Directory of Open Access Journals (Sweden)

Thomas Scaffidi

2017-11-01

Full Text Available We introduce exactly solvable gapless quantum systems in d dimensions that support symmetry-protected topological (SPT edge modes. Our construction leads to long-range entangled, critical points or phases that can be interpreted as critical condensates of domain walls “decorated” with dimension (d-1 SPT systems. Using a combination of field theory and exact lattice results, we argue that such gapless SPT systems have symmetry-protected topological edge modes that can be either gapless or symmetry broken, leading to unusual surface critical properties. Despite the absence of a bulk gap, these edge modes are robust against arbitrary symmetry-preserving local perturbations near the edges. In two dimensions, we construct wave functions that can also be interpreted as unusual quantum critical points with diffusive scaling in the bulk but ballistic edge dynamics.

Evaluation of Spatial Perspective Taking Skills using a Digital Game with Different Levels of Immersion

Directory of Open Access Journals (Sweden)

Laura Freina

2017-09-01

Full Text Available The present paper presents the results of an experiment aimed at assessing the impact of different levels of immersion on performance in a Spatial Perspective Taking (SPT task. Since SPT is an embodied skill, the hypothesis was that the more immersive a tool is, the better the performance should be. Ninety-eight students from a local primary school have played with three different versions of a game: (i completely immersive with a Head Mounted Display, (ii semi immersive on a computer screen and (iii non-immersive where no movements were possible for the player. Results showed that in the immersive versions of the game, players obtained higher scores than in the non-immersive version, suggesting that an immersive tool can better support performance in a SPT task.

Analysis of the association between spawning time QTL markers and the biannual spawning behavior in rainbow trout (Oncorhynchus mykiss

Directory of Open Access Journals (Sweden)

Nelson Colihueque

2010-01-01

Full Text Available The rainbow trout is a salmonid fish that occasionally exhibits broodstocks with biannual spawning behavior, a phenomenon known as a double annual reproductive cycle (DARC. Spawning time quantitative trait loci (SPT-QTLs affect the time of the year that female rainbow trout spawn and may influence expression of the DARC trait. In this study, microsatellite markers linked and unlinked to SPT-QTLs were genotyped to investigate the underlying genetics of this trait. SPT-QTLs influenced the DARC trait since in two case-control comparisons three linked markers (OmyFGT12TUF, One3ASC and One19ASC had significant levels of allelic frequency differentiation and marker-character association. Furthermore, alleles of One3ASC and One19ASC had significantly higher frequencies in populations that carried the DARC trait.

Huwelijk in Nederland, 1967 [Marriage in the Netherlands, 1967

NARCIS (Netherlands)

Kooy, G.A.

2007-01-01

Detailed background data on marriage and family / religion and occupation / satisfaction with job / household and mutual friends / perceptions of partner / personal worries / relationships with mutual friends / self description / personal problems / opinions on financial matters / socio-cultural and

“Turn to pollute”: poluição atmosférica e modelo de desenvolvimento no “milagre” brasileiro (1967-1973

Directory of Open Access Journals (Sweden)

Regina Horta Duarte

Full Text Available Resumo Em 1972, durante a Conferência de Estocolmo, a oposição do Brasil às propostas de regulamentação ambiental despertou fortes críticas internacionais. Este artigo discute as conexões entre a ditadura civil-militar, o milagre econômico e a política ambiental brasileira entre 1967 e 1973, com foco na poluição atmosférica. Como outros países latino-americanos, o Brasil enfrentava dilemas entre desenvolvimento e qualidade ambiental. Algumas instituições propuseram soluções diversas para o tema, como Cepal e Redpanaire, ambas agências das Nações Unidas na América Latina. A polêmica da poluição atmosférica explicita as contradições do regime civil-militar brasileiro, que justificava a poluição como meio para o desenvolvimento e a luta contra a pobreza ao mesmo tempo em que adotava políticas que resultaram em concentração de riqueza. Enquanto o poder de compra e a qualidade de vida das elites cresciam rapidamente, a maioria da população brasileira experimentou altas taxas de mortalidade infantil, más condições de saúde, ambientes degradados e significativas perdas salariais. A ditadura deixou para o Brasil um duplo legado de aprofundamento da desigualdade social e da degradação ambiental.

Polybrominated diphenyl ethers (PBDEs) and their methoxylated derivatives in pike from Swedish waters with emphasis on temporal trends, 1967-2000

International Nuclear Information System (INIS)

Kierkegaard, A.; Bignert, A.; Sellstroem, U.; Olsson, M.; Asplund, L.; Jansson, B.; Wit, C.A. de

2004-01-01

Temporal trends of five tetra- to hexabromodiphenyl ethers [BDE47, BDE99, BDE100, BDE153 and BDE154) and two methoxy-tetraBDEs [6-methoxy-2,2',4,4'- tetraBDE (6-MeO-BDE47) and 2'-methoxy-2,3',4,5'- tetraBDE (2'-MeO-BDE68)] in pike from Lake Bolmen for the years 1967-2000, are presented. All BDE congeners show increasing trends up to the mid-1980s (Σ5PBDE from 60 to 1600 pg/g wet weight in 1989, i.e. a more than 25-fold increase), and then decrease or level off. The decreasing trends of PBDEs after the 1980s were considerably slower in the present study than was found in a study of an environmental matrix from the Baltic Proper covering the same time period. This difference suggests local sources near Lake Bolmen. The MeO-BDEs show initially decreasing concentrations, which for 6-MeO-BDE47 continues until the early 1990s. The concentrations of 6-MeO-BDE47 in herring from five locations along the Swedish coast increased from south to north in the Baltic Sea. No correlation between the concentrations of the BDE congeners and the MeO-BDEs was observed, indicating sources other than PBDEs for these compounds. The presence of MeO-BDEs in fish from lakes with different characteristics suggests a natural production not favoured by eutrophication, or dependent on sampling season and geographical location. - PBDEs and MeO-BDEs show different temporal trends in pike from a Swedish lake suggesting different sources

Prevalence of IgE sensitization in Danish children with suspected asthma

DEFF Research Database (Denmark)

Hoffmann-Petersen, Benjamin; Høst, Arne; Larsen, Kirsten Toksvig

2013-01-01

OBJECTIVE: The aim of this article was to estimate the prevalence of IgE sensitization in Danish children with suspected asthma and to characterize the pattern of sensitization. STUDY DESIGN: We performed a cross-sectional study including 1744 children from 0 to 15 yr suspected of asthma who were...... referred to pediatric outpatient clinics in the region of southern Denmark from 2003 to 2005. The children were subjected to an extensive questionnaire-based interview, clinical examination, and both skin prick testing (SPT) and IgE measurements for 17 allergens. RESULTS: Asthma was confirmed in 1024...... of the 1744 children. Among the children in whom the asthma diagnosis was confirmed, sensitization to one or more of the 17 allergens tested was found in 67.5% by either SPT or s-IgE ≥ class 2. Sensitization to any food allergen was found in 31.1%, to any outdoor allergen in 36.2%, and to any indoor allergen...

Remote Minehunting System (RMS)

Science.gov (United States)

2015-12-01

1449.4 1449.4 744.6 Confidence Level Confidence Level of cost estimate for current APB: 50% The Independent Cost Estimate to support the RMS Nunn...which the Derpartment has been successful. It is difficult to calculate mathematically the precise confidence levels associated with life-cycle cost...Baseline (TY $M) Initial PAUC Production Estimate Changes PAUC Development Estimate Econ Qty Sch Eng Est Oth Spt Total 12.957 -0.752 3.262 2.950 0.454

Yeast Interacting Proteins Database: YOR047C, YKL038W [Yeast Interacting Proteins Database

Lifescience Database Archive (English)

Full Text Available racts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a...Bait description Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose senso...rs Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the tra

Diagnostic value of scratch-chamber test, skin prick test, histamine release and specific IgE in birch-allergic patients with oral allergy syndrome to apple

DEFF Research Database (Denmark)

Osterballe, M; Scheller, R; Stahl Skov, P

2003-01-01

BACKGROUND: The aim of the study was to examine the diagnostic value of skin prick test (SPT), scratch-chamber test (SCT), histamine release (HR) and specific immunoglobulin E (IgE) in birch-allergic patients with oral allergy syndrome to apple. METHODS: Ten birch-allergic patients with oral...... a detailed case history about symptoms of oral allergy syndrome combined with a SPT with fresh apple peel or A72 will be useful....

Distribution pattern of juveniles of the pink shrimps Farfantepenaeus brasiliensis (Latreille, 1817 and F. paulensis (Pérez-Farfante, 1967 on the southeastern Brazilian coast

Directory of Open Access Journals (Sweden)

Rogério Caetano da Costa

Full Text Available Abstract The spatio-temporal distribution of juveniles of the pink shrimps Farfantepenaeus brasiliensis (Latreille, 1817 and Farfantepenaeus paulensis (Pérez-Farfante, 1967 in the Ubatuba region (SP was investigated. Sampling was performed in the bays of Ubatumirim (UBM, Ubatuba (UBA and Mar Virado (MV. A total of 2,018 F. brasiliensis and F. paulensis were collected. The largest catch of juveniles of both species occurred in UBA (N = 867, followed by UBM (N = 729 and MV (N= 422. The bottom sediment in MV had the highest silt and clay content, which explains the negative correlation of the substrate with the abundance of both species. Temperature was positively correlated with the abundance of both species. Juveniles were highly abundant in shallower areas in the summer of 1998. The high rainfall in this El Niño period may have lowered the salinity in estuarine waters and led the shrimps to move to coastal areas in search of higher salinities such as in bays. With this unusually early reduction in salinity, individuals migrated to the bay before the closed season began and thus became more exposed to fishing. We confirmed that monitoring environmental variations, especially in El Niño years, is essential for understanding the distribution patterns of juveniles of both species.

Effects of periodontal treatment on carotid intima-media thickness in patients with lifestyle-related diseases: Japanese prospective multicentre observational study.

Science.gov (United States)

Kudo, Chieko; Shin, Wee Soo; Sasaki, Nobuhiro; Harai, Kazuo; Kato, Kai; Seino, Hiroaki; Goke, Eiji; Fujino, Takemasa; Kuribayashi, Nobuichi; Pearce, Youko Onuki; Taira, Masato; Matsushima, Ryoji; Minabe, Masato; Takashiba, Shogo

2018-01-12

Atherosclerosis, a chronic inflammatory disease in arterial blood vessels, is one of the major causes of death in worldwide. Meanwhile, periodontal disease is a chronic inflammatory disease caused by infection with periodontal pathogens such as P. gingivalis (Porphyromonas gingivalis). Several studies have reported association between periodontal infection and atherosclerosis, but direct investigation about the effects of periodontal treatment on atherosclerosis has not been reported. We have planned Japanese local clinics to determine the relationship between periodontal disease and atherosclerosis under collaborative with medical and dental care. A prospective, multicentre, observational study was conducted including 38 medical patients with lifestyle-related diseases in the stable period under consultation at participating medical clinics and 92 periodontal patients not undergoing medical treatment but who were consulting at participating dental clinics. Systemic and periodontal examinations were performed before and after periodontal treatment. At baseline, LDL-C (low-density lipoprotein cholesterol) levels and percentage (%) of mobile teeth were positively related to plasma IgG (immunoglobulin) antibody titer against P. gingivalis with multivariate analysis. Corresponding to improvements in periodontal clinical parameters after treatment, right and left max IMT (maximum intima-media thickness) levels were decreased significantly after treatment (SPT-S: start of supportive periodontal therapy, SPT-1y: at 1 year under SPT, and SPT-3y: at 3 years under SPT). The present study has clarified our previous univariate analysis results, wherein P. gingivalis infection was positively associated with progression of atherosclerosis. Thus, routine screening using plasma IgG antibody titer against P. gingivalis and periodontal treatment under collaborative with medical and dental care may prevent cardiovascular accidents caused by atherosclerosis.

Small punch test evaluation methods for material characterisation

Energy Technology Data Exchange (ETDEWEB)

Janča, Adam, E-mail: adam.janca@fjfi.cvut.cz; Siegl, Jan, E-mail: jan.siegl@fjfi.cvut.cz; Haušild, Petr, E-mail: petr.hausild@fjfi.cvut.cz

2016-12-01

The Small Punch Test (SPT) is one of the most widespread mechanical testing methods using miniaturized specimens. The paper presented deals with the time independent SPT, in which a flat specimen is bent by means of a (hemi)spherical punch moving at a constant velocity. The main goal is to relate the measured data to deformation processes taking place during specimen loading. Understanding of such relations is crucial for characterizing a material using any non-standardized experimental procedure. Using enhanced instrumentation, not only traditional load-displacement or load-deflection curves could be obtained, but also specimen thinning could be continuously measured and evaluated. Five alloys having a broad range of mechanical properties were tested. The results obtained were evaluated using both traditional and newly proposed methods and they were correlated with results of the conventional tensile test. The methods proposed seem to lead to a universal correlation between SPT results and tensile characteristics. - Highlights: • The newly proposed methodology significantly improved results of SPT. • Plastic deformation starts inside the specimen from the very beginning of loading. • Specimen thinning = punch displacement−specimen deflection. • Material response to loading is well illustrated by the novel load-thinning curve.

Somatic Genetic Variation in Solid Pseudopapillary Tumor of the Pancreas by Whole Exome Sequencing

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Meng Guo

2017-01-01

Full Text Available Solid pseudopapillary tumor of the pancreas (SPT is a rare pancreatic disease with a unique clinical manifestation. Although CTNNB1 gene mutations had been universally reported, genetic variation profiles of SPT are largely unidentified. We conducted whole exome sequencing in nine SPT patients to probe the SPT-specific insertions and deletions (indels and single nucleotide polymorphisms (SNPs. In total, 54 SNPs and 41 indels of prominent variations were demonstrated through parallel exome sequencing. We detected that CTNNB1 mutations presented throughout all patients studied (100%, and a higher count of SNPs was particularly detected in patients with older age, larger tumor, and metastatic disease. By aggregating 95 detected variation events and viewing the interconnections among each of the genes with variations, CTNNB1 was identified as the core portion in the network, which might collaborate with other events such as variations of USP9X, EP400, HTT, MED12, and PKD1 to regulate tumorigenesis. Pathway analysis showed that the events involved in other cancers had the potential to influence the progression of the SNPs count. Our study revealed an insight into the variation of the gene encoding region underlying solid-pseudopapillary neoplasm tumorigenesis. The detection of these variations might partly reflect the potential molecular mechanism.

Synthesis and characterization of 10%Gd doped ceria (GDC) deposited on NiO-GDC anode-grade-ceramic substrate as half cell for IT-SOFC

DEFF Research Database (Denmark)

Chourashiya, M. G.; Jadhav, L. D.

2011-01-01

In the present research work spray pyrolysis technique (SPT) is employed to synthesize GDC (10%Gd doped ceria) thin films on anode-grade-ceramic substrate (porous NiO-GDC). The film/substrate structure was characterized for their micro-structural and electrical properties along with their interfa......In the present research work spray pyrolysis technique (SPT) is employed to synthesize GDC (10%Gd doped ceria) thin films on anode-grade-ceramic substrate (porous NiO-GDC). The film/substrate structure was characterized for their micro-structural and electrical properties along...... with their interfacial-quality. By optimization of preparative parameters of SPT and modification of surface of anode-grade ceramic substrate, we were able to prepare the GDC films having thickness of the order of 13 μm on NiO-GDC substrate. Further to improve the interfacial quality and densification of film, annealing...

Quantitative linkage genome scan for atopy in a large collection of Caucasian families

DEFF Research Database (Denmark)

Webb, BT; van den Oord, E; Akkari, A

2007-01-01

adulthood, asthma is frequently associated also with quantitative measures of atopy. Genome wide quantitative multipoint linkage analysis was conducted for serum IgE levels and percentage of positive skin prick test (SPT(per)) using three large groups of families originally ascertained for asthma....... In this report, 438 and 429 asthma families were informative for linkage using IgE and SPT(per) which represents 690 independent families. Suggestive linkage (LOD >/= 2) was found on chromosomes 1, 3, and 8q with maximum LODs of 2.34 (IgE), 2.03 (SPT(per)), and 2.25 (IgE) near markers D1S1653, D3S2322-D3S1764...... represents one of the biggest genome scans so far reported for asthma related phenotypes. This study also demonstrates the utility of increased sample sizes and quantitative phenotypes in linkage analysis of complex disorders....

Anther development stage and gamma radiation effects on tomato anther-derived callus formation

International Nuclear Information System (INIS)

Brasileiro, Ana Christina R.; Willadino, Lilia; Guerra, Marcelo; Colaco, Waldeciro; Meunier, Isabelle; Camara, Terezinha R.

1999-01-01

Two experiments were carried (I) to determine tomato anther development stage influence on callus production; and (II) to investigate gamma radiation effects on anther culture. In the first experiment, anthers of a tomato hybrid (IPA 5 x Rotam 4-F 1 ) were grown on three media. Although calli were induced at all stages of anther development, varying from prophase I to mono nucleate microspore, callus frequency decreased as anther development progressed and calli induction were not significantly affected by all media tested. Anthers containing prophase I meiocytes produced the highest calli frequency. Anther and flower bud length both were significantly correlated with anther development stage. In the second experiment, seed and floral buds of tomato hybrids IPA 5 x Rotam 4 (F 2 ), IPA 6 x Rotam 4 (F 2 ) and IPA 8 x 217.1 (F 2 ) were submitted to gamma-ray and anthers were plated on two media described by Gresshoff and Doy (1972) supplemented with 2.0 mg L -1 NAA + 5.0 mg L -1 KIN and 2.0 mg L -1 NAA + 1.0 mg L -1 KIN. No significant differences for genotype and dosage testes were found for calli formation. (author)

Ionospheric variations during the 13 September 1967 storm

International Nuclear Information System (INIS)

Goel, M.K.; Rao, B.C.N.

1980-01-01

The storm time variations in N sub(e), T sub(e), and ion drifts are studied for a mid-latitude station, St. Santin (44.11 0 N, 2.3 0 E) using incoherent scatter radar data. It is observed that there is an increase in N sub(e) with a corresponding decrease in T sub(e) at 350 km and the drifts are upward when compared with the quiet time drifts. These drifts are shown to be related to changes in magnetic field and hence they may be due to an electrodynamic effect. It is established from the N sub(e) and T sub(e) profile changes that the differences in the ionospheric effects at different times reported earlier by the authors for the same storm are due to the storm-time effect and not due to a longitude effect. (author)

Survey of gastrointestinal reactions to foods in adults in relation to atopy, presence of mucus in the stools, swelling of joints and arthralgia in patients with gastrointestinal reactions to foods.

Science.gov (United States)

Bengtsson, U; Hanson, L A; Ahlstedt, S

1996-12-01

Food intolerance in adults is mostly associated with vague symptoms and not clearly related to atopy and food allergy. A combination of different pathogenetic mechanisms may be responsible for the symptoms. The aim of this study was to describe patients with a history of food-related gastrointestinal symptoms in relation to the presence of mucus in the stools, joint swelling and arthralgia and to determine whether or not there is an association between the presence of these parameters, atopic disease and the presence of immune complexes in serum. Fifty-eight patients consecutively referred to our clinic with food-related gastrointestinal symptoms were investigated. Thirty-five patients (60%) had mucus in their stools, 24 patients (41%) complained about joint swelling and 41 patients (71%) had arthralgia. There were no correlations between these parameters and atopy according to Phadiatope test or skin prick test (SPT). No correlations were found between the occurrence of mucus in the stools, arthralgia and joint swelling. There were significantly higher levels of circulating immune complexes in patients with a history of arthralgia compared with patients with no such history (P mucus in the stools. However, there were significant positive correlations between food-related gastrointestinal symptoms in the following instances: chocolate-induced gastrointestinal symptoms and mucus in the stools (P = 0.006), vegetable-induced gastrointestinal symptoms and mucus in the stools (P = 0.002) and meat-induced gastrointestinal symptoms and mucus in the stools (P = 0.003). In a group of individuals without food-related symptoms investigated separately, a very low frequency of mucus in the stools, joint swelling and arthralgia was seen (none, two and three individuals of the 20 subjects, respectively). Of 41 patients with immediate onset of gastrointestinal symptoms, 20 were atopic according to Phadiatope and SPT. Of 11 patients with late onset of symptoms 10 were negative in

High Time-Resolved Kinetic Temperatures of Solar Wind Minor Ions Measured with SOHO/CELIAS/CTOF

Science.gov (United States)

Janitzek, N. P.; Berger, L.; Drews, C.; Wimmer-Schweingruber, R. F.

2017-12-01

Solar wind heavy ions with an atomic number Z > 2 are referred to as minor ions since they represent a fraction of less than one percent of all solar wind ions. They can be therefore regarded as test particles, only reacting to but not driving the dynamics of the solar wind plasma, which makes them a unique diagnostic tool for plasma wave phenomena both in the solar atmosphere and the extended heliosphere. In the past, several studies have investigated the kinetic temperatures of minor ions, but due to low counting statistics these studies are based on ion velocity distribution functions (VDFs) recorded over time periods of several hours. The Charge Time-Of-Flight (CTOF) mass spectrometer as part of the Charge, ELement and Isotope Analysis System (CELIAS) onboard the SOlar and Heliospheric Observatory (SOHO) provides solar wind heavy ion 1D radial VDFs with excellent charge state separation, an unprecedented cadence of 5 minutes and very high counting statistics, exceeding similar state-of-the-art instruments by a factor of ten. In our study, based on CTOF measurements at Langrangian point L1 between DOY 150 and DOY 220 in 1996, we investigate systematically the influence of the VDF time resolution on the derived kinetic temperatures for solar wind silicon and iron ions. The selected ion set spans a wide range of mass-per-charge from 3 amu/e heavy ions with ion-cyclotron waves.

Material Development Study for a Hazardous Chemical Protective Clothing Outfit

Science.gov (United States)

1980-08-01

Analytical - X VCM Vinyl Chloride Unavailable - X ZEC Zectran Insoluble X X ZCN Zinc Cyanide Insoluble X X ZCT Zirconium Tetrachloride Water React. X 64...Environmental Rating of Plastics, Reprints of Design News, R. L. Peters , 6 December 1967, 20 December 1967, 22 November 1967, 8 November 1967. 13. Modern

Movement behaviour and video tracking of Milnesium tardigradum Doyère, 1840 (Eutardigrada, Apochela)

NARCIS (Netherlands)

Shcherbakov, D.; Schill, R.O.; Brümmer, F.; Blum, M.

2010-01-01

Tardigrades or ‘water-bears’ live in moist environments with a high degree of gaseous exchange. In tardigrades, locomotion is essential, e.g. for feeding, to find sexual partners and to adjust the level of hydration by moving to wetter or dryer environments. Here we report on the movement behaviour

Polybrominated diphenyl ethers (PBDEs) and their methoxylated derivatives in pike from Swedish waters with emphasis on temporal trends, 1967-2000

Energy Technology Data Exchange (ETDEWEB)

Kierkegaard, A.; Bignert, A.; Sellstroem, U.; Olsson, M.; Asplund, L.; Jansson, B.; Wit, C.A. de

2004-07-01

Temporal trends of five tetra- to hexabromodiphenyl ethers [BDE47, BDE99, BDE100, BDE153 and BDE154) and two methoxy-tetraBDEs [6-methoxy-2,2',4,4'- tetraBDE (6-MeO-BDE47) and 2'-methoxy-2,3',4,5'- tetraBDE (2'-MeO-BDE68)] in pike from Lake Bolmen for the years 1967-2000, are presented. All BDE congeners show increasing trends up to the mid-1980s ({sigma}5PBDE from 60 to 1600 pg/g wet weight in 1989, i.e. a more than 25-fold increase), and then decrease or level off. The decreasing trends of PBDEs after the 1980s were considerably slower in the present study than was found in a study of an environmental matrix from the Baltic Proper covering the same time period. This difference suggests local sources near Lake Bolmen. The MeO-BDEs show initially decreasing concentrations, which for 6-MeO-BDE47 continues until the early 1990s. The concentrations of 6-MeO-BDE47 in herring from five locations along the Swedish coast increased from south to north in the Baltic Sea. No correlation between the concentrations of the BDE congeners and the MeO-BDEs was observed, indicating sources other than PBDEs for these compounds. The presence of MeO-BDEs in fish from lakes with different characteristics suggests a natural production not favoured by eutrophication, or dependent on sampling season and geographical location. - PBDEs and MeO-BDEs show different temporal trends in pike from a Swedish lake suggesting different sources.

A Personal Account of the History of Historical Demography in Europe at the End of the Glorious Thirty (1967-1975

Directory of Open Access Journals (Sweden)

Antoinette Fauve-Chamoux

2017-04-01

Full Text Available Encouraged by her masters at the Annales School—historians Fernand Braudel and Emmanuel Le Roy Ladurie, demographer Louis Henry from Institut National d’Etudes Démographiques (INED, and sociologist Peter Laslett from Cambridge—the author, a baby-boomer, experienced major socio-economic and cultural changes in family behavior and reproduction models induced in Europe by the revolutionary events of 1968 in Paris. In this essay, she presents a personal account of the history of historical demography in Europe, between 1967 and 1975, in other words at the end of the post-WWII Glorious Thirty period (1945-1975. She then became involved in the development of a global network that had been formed in 1960 in Stockholm, linking professional national and international associations and academic units in Historical Demography and History of the Family. This network spread quickly overseas during the following decades. The period under study was marked by the beginning of important behavioral changes in socio-economic contexts and attitudes to family life, gender and human reproduction. These major shifts were called the Second Demographic Transition by two Dutch demographers, inspired by French scholars. The year 1976 is identified as a major turning point for Historical Demography as a discipline, mostly through the creation of the Social Science History Association and the Journal of Family History, which brought new theoretical approaches and methodologies. A generation of productive researchers appeared with the end of the 20th century and the new millennium. They took advantage of an increasingly digitalized world to widely disseminate a rich store of knowledge about past population behavior gathered since the 1960s by their predecessors.

GPS, BDS and Galileo ionospheric correction models: An evaluation in range delay and position domain

Science.gov (United States)

Wang, Ningbo; Li, Zishen; Li, Min; Yuan, Yunbin; Huo, Xingliang

2018-05-01

The performance of GPS Klobuchar (GPSKlob), BDS Klobuchar (BDSKlob) and NeQuick Galileo (NeQuickG) ionospheric correction models are evaluated in the range delay and position domains over China. The post-processed Klobuchar-style (CODKlob) coefficients provided by the Center for Orbit Determination in Europe (CODE) and our own fitted NeQuick coefficients (NeQuickC) are also included for comparison. In the range delay domain, BDS total electrons contents (TEC) derived from 20 international GNSS Monitoring and Assessment System (iGMAS) stations and GPS TEC obtained from 35 Crust Movement Observation Network of China (CMONC) stations are used as references. Compared to BDS TEC during the short period (doy 010-020, 2015), GPSKlob, BDSKlob and NeQuickG can correct 58.4, 66.7 and 54.7% of the ionospheric delay. Compared to GPS TEC for the long period (doy 001-180, 2015), the three ionospheric models can mitigate the ionospheric delay by 64.8, 65.4 and 68.1%, respectively. For the two comparison cases, CODKlob shows the worst performance, which only reduces 57.9% of the ionospheric range errors. NeQuickC exhibits the best performance, which outperforms GPSKlob, BDSKlob and NeQuickG by 6.7, 2.1 and 6.9%, respectively. In the position domain, single-frequency stand point positioning (SPP) was conducted at the selected 35 CMONC sites using GPS C/A pseudorange with and without ionospheric corrections. The vertical position error of the uncorrected case drops significantly from 10.3 m to 4.8, 4.6, 4.4 and 4.2 m for GPSKlob, CODKlob, BDSKlob and NeQuickG, however, the horizontal position error (3.2) merely decreases to 3.1, 2.7, 2.4 and 2.3 m, respectively. NeQuickG outperforms GPSKlob and BDSKlob by 5.8 and 1.9% in vertical component, and by 25.0 and 3.2% in horizontal component.

Geomorphic Identification and Verification of Recent Sedimentation Patterns in the Woonasquatucket River, North Providence, Rhode Island

Science.gov (United States)

2007-03-01

1954 52.0 465 Diane 8/19/1955 Tropical Storm 29 1965 35.4 438 1963-1967 (Statewide) Alma 6/14/1966 Extratropical 30 1996 42.4 438 10/20/1996...1960 9/12/1960 Extratropical Tropical Storm Hurricane (Cat 2) 34 1990 48.1 402 Bob 8/19/1991 Hurricane (Cat 2) 35 1964 29.2 401 1963-1967...Island to use the Scotch loom, a reproduction of a power loom used in Europe , and was also the first mill in the United States to produce worsteds

La falta de Laclau: lo imaginario

Directory of Open Access Journals (Sweden)

Julio Aibar

2014-06-01

Full Text Available En la obra de Laclau hay una clara deficiencia: la del registro de lo Imaginario. La no inclusión de ese registro en el andamiaje conceptual que sostiene a la teoría de la hegemonía, hace que la misma sea endeble en sus principales desarrollos. En este artículo doy cuenta, a la luz de la obra de Lacan, del silencio teórico de Laclau, para después explorar las consecuencias de dicho silencio para el análisis político.

Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether

OpenAIRE

Martínez-Montañés, Fernando; Lone, Museer A.; Hsu, Fong-Fu; Schneiter3, Roger

2017-01-01

Long-chain bases (LCBs) are the precursors to ceramide and sphingolipids in eukaryotic cells. They are formed by the action of serine palmitoyl-CoA transferase (SPT), a complex of integral membrane proteins located in the endoplasmic reticulum. SPT activity is negatively regulated by Orm proteins to prevent the toxic overaccumulation of LCBs. Here we show that overaccumulation of LCBs in yeast results in their conversion to a hitherto undescribed LCB derivative, an LCB vinyl ether. The ...

Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase.

Science.gov (United States)

Genin, Michael J; Gonzalez Valcarcel, Isabel C; Holloway, William G; Lamar, Jason; Mosior, Marian; Hawkins, Eric; Estridge, Thomas; Weidner, Jeffrey; Seng, Thomas; Yurek, David; Adams, Lisa A; Weller, Jennifer; Reynolds, Vincent L; Brozinick, Joseph T

2016-06-23

To develop novel treatments for type 2 diabetes and dyslipidemia, we pursued inhibitors of serine palmitoyl transferase (SPT). To this end compounds 1 and 2 were developed as potent SPT inhibitors in vitro. 1 and 2 reduce plasma ceramides in rodents, have a slight trend toward enhanced insulin sensitization in DIO mice, and reduce triglycerides and raise HDL in cholesterol/cholic acid fed rats. Unfortunately these molecules cause a gastric enteropathy after chronic dosing in rats.

Standardization of food allergen extracts for skin prick test

DEFF Research Database (Denmark)

Skamstrup Hansen, K; Bindslev-Jensen, C; Skov, P S

2001-01-01

The aim of the study was to standardize and evaluate technically optimized food allergen extracts for use in skin prick test (SPT). The standardization procedure comprised 36 allergic histories in 32 food allergic patients with 21 healthy, non-atopic individuals serving as controls. The patients...... had a history of allergic symptoms upon ingestion of either cow's milk (n=3), hen's egg (n=9), wheat (n=4), hazelnut (n=14) or cod (n=6). They also had specific IgE in serum to the food in question and a positive SPT with a fresh preparation of the food. The diagnosis had been confirmed by a double......-blind, placebo-controlled food challenge, except for the hazelnut-allergic patients. The controls were subjected to an open food challenge with all the foods to ensure tolerance. The standardization was performed by means of titrated SPT in accordance with the guidelines on biological standardization from...

Quantitative linkage genome scan for atopy in a large collection of Caucasian families

DEFF Research Database (Denmark)

Webb, BT; van den Oord, E; Akkari, A

2007-01-01

Quantitative phenotypes correlated with a complex disorder offer increased power to detect linkage in comparison to affected-unaffected classifications. Asthma is a complex disorder characterized by periods of bronchial obstruction and increased bronchial hyper reactivity. In childhood and early...... adulthood, asthma is frequently associated also with quantitative measures of atopy. Genome wide quantitative multipoint linkage analysis was conducted for serum IgE levels and percentage of positive skin prick test (SPT(per)) using three large groups of families originally ascertained for asthma....... In this report, 438 and 429 asthma families were informative for linkage using IgE and SPT(per) which represents 690 independent families. Suggestive linkage (LOD >/= 2) was found on chromosomes 1, 3, and 8q with maximum LODs of 2.34 (IgE), 2.03 (SPT(per)), and 2.25 (IgE) near markers D1S1653, D3S2322-D3S1764...

Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.

Science.gov (United States)

Demény, Màté A; Soutoglou, Evi; Nagy, Zita; Scheer, Elisabeth; Jànoshàzi, Agnes; Richardot, Magalie; Argentini, Manuela; Kessler, Pascal; Tora, Laszlo

2007-03-21

TFIID plays a role in nucleating RNA polymerase II preinitiation complex assembly on protein-coding genes. TFIID is a multisubunit complex comprised of the TATA box binding protein (TBP) and 14 TBP-associated factors (TAFs). Another class of multiprotein transcriptional regulatory complexes having histone acetyl transferase (HAT) activity, and containing TAFs, includes TFTC, STAGA and the PCAF/GCN5 complex. Looking for as yet undiscovered subunits by a proteomic approach, we had identified TAF8 and SPT7L in human TFTC preparations. Subsequently, however, we demonstrated that TAF8 was not a stable component of TFTC, but that it is present in a small TAF complex (SMAT), containing TAF8, TAF10 and SPT7L, that co-purified with TFTC. Thus, TAF8 is a subunit of both TFIID and SMAT. The latter has to be involved in a pathway of complex formation distinct from the other known TAF complexes, since these three histone fold (HF)-containing proteins (TAF8, TAF10 and SPT7L) can never be found together either in TFIID or in STAGA/TFTC HAT complexes. Here we show that TAF8 is absolutely necessary for the integration of TAF10 in a higher order TFIID core complex containing seven TAFs. TAF8 forms a heterodimer with TAF10 through its HF and proline rich domains, and also interacts with SPT7L through its C-terminal region, and the three proteins form a complex in vitro and in vivo. Thus, the TAF8-TAF10 and TAF10-SPT7L HF pairs, and also the SMAT complex, seem to be important regulators of the composition of different TFIID and/or STAGA/TFTC complexes in the nucleus and consequently may play a role in gene regulation.

Resolving Fast, Confined Diffusion in Bacteria with Image Correlation Spectroscopy.

Science.gov (United States)

Rowland, David J; Tuson, Hannah H; Biteen, Julie S

2016-05-24

By following single fluorescent molecules in a microscope, single-particle tracking (SPT) can measure diffusion and binding on the nanometer and millisecond scales. Still, although SPT can at its limits characterize the fastest biomolecules as they interact with subcellular environments, this measurement may require advanced illumination techniques such as stroboscopic illumination. Here, we address the challenge of measuring fast subcellular motion by instead analyzing single-molecule data with spatiotemporal image correlation spectroscopy (STICS) with a focus on measurements of confined motion. Our SPT and STICS analysis of simulations of the fast diffusion of confined molecules shows that image blur affects both STICS and SPT, and we find biased diffusion rate measurements for STICS analysis in the limits of fast diffusion and tight confinement due to fitting STICS correlation functions to a Gaussian approximation. However, we determine that with STICS, it is possible to correctly interpret the motion that blurs single-molecule images without advanced illumination techniques or fast cameras. In particular, we present a method to overcome the bias due to image blur by properly estimating the width of the correlation function by directly calculating the correlation function variance instead of using the typical Gaussian fitting procedure. Our simulation results are validated by applying the STICS method to experimental measurements of fast, confined motion: we measure the diffusion of cytosolic mMaple3 in living Escherichia coli cells at 25 frames/s under continuous illumination to illustrate the utility of STICS in an experimental parameter regime for which in-frame motion prevents SPT and tight confinement of fast diffusion precludes stroboscopic illumination. Overall, our application of STICS to freely diffusing cytosolic protein in small cells extends the utility of single-molecule experiments to the regime of fast confined diffusion without requiring advanced

A serine palmitoyltransferase inhibitor blocks hepatitis C virus replication in human hepatocytes.

Science.gov (United States)

Katsume, Asao; Tokunaga, Yuko; Hirata, Yuichi; Munakata, Tsubasa; Saito, Makoto; Hayashi, Hitohisa; Okamoto, Koichi; Ohmori, Yusuke; Kusanagi, Isamu; Fujiwara, Shinya; Tsukuda, Takuo; Aoki, Yuko; Klumpp, Klaus; Tsukiyama-Kohara, Kyoko; El-Gohary, Ahmed; Sudoh, Masayuki; Kohara, Michinori

2013-10-01

Host cell lipid rafts form a scaffold required for replication of hepatitis C virus (HCV). Serine palmitoyltransferases (SPTs) produce sphingolipids, which are essential components of the lipid rafts that associate with HCV nonstructural proteins. Prevention of the de novo synthesis of sphingolipids by an SPT inhibitor disrupts the HCV replication complex and thereby inhibits HCV replication. We investigated the ability of the SPT inhibitor NA808 to prevent HCV replication in cells and mice. We tested the ability of NA808 to inhibit SPT's enzymatic activity in FLR3-1 replicon cells. We used a replicon system to select for HCV variants that became resistant to NA808 at concentrations 4- to 6-fold the 50% inhibitory concentration, after 14 rounds of cell passage. We assessed the ability of NA808 or telaprevir to inhibit replication of HCV genotypes 1a, 1b, 2a, 3a, and 4a in mice with humanized livers (transplanted with human hepatocytes). NA808 was injected intravenously, with or without pegylated interferon alfa-2a and HCV polymerase and/or protease inhibitors. NA808 prevented HCV replication via noncompetitive inhibition of SPT; no resistance mutations developed. NA808 prevented replication of all HCV genotypes tested in mice with humanized livers. Intravenous NA808 significantly reduced viral load in the mice and had synergistic effects with pegylated interferon alfa-2a and HCV polymerase and protease inhibitors. The SPT inhibitor NA808 prevents replication of HCV genotypes 1a, 1b, 2a, 3a, and 4a in cultured hepatocytes and in mice with humanized livers. It might be developed for treatment of HCV infection or used in combination with pegylated interferon alfa-2a or HCV polymerase or protease inhibitors. Copyright © 2013 AGA Institute. Published by Elsevier Inc. All rights reserved.

House dust bioactivities predict skin prick test reactivity for children with high risk of allergy.

Science.gov (United States)

Kim, Haejin; Tse, Kevin; Levin, Linda; Bernstein, David; Reponen, Tiina; LeMasters, Grace; Lummus, Zana; Horner, Anthony A

2012-06-01

Although evidence suggests that ambient exposures to endotoxin and other immunostimulants during early life influence allergic risk, efforts to understand this host-environment relationship have been hampered by a paucity of relevant assays. These investigations determined whether parameters of house dust extract (HDE) bioactivity were predictive of allergen skin prick test (SPT) reactivity for infants at high risk of allergy participating in the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS). We conducted a nested case-control study, selecting 99 CCAAPS children who had positive SPT results to at least 1 aeroallergen at age 3 years and 101 subjects with negative SPT results. HDEs were prepared from dust samples collected from the subjects' homes at age 1 year. Murine splenocytes and bone marrow-derived dendritic cells were incubated with HDEs, and supernatant cytokine concentrations were determined by means of ELISA. Alternatively, bone marrow-derived dendritic cells were preincubated with HDEs, and then LPS-induced IL-6 responses were assessed. HDE endotoxin levels were determined by using the limulus amebocyte lysate assay. HDEs derived from the homes of children with positive (cases) and negative (control subjects) SPT results had similar bioactivities. However, when cases were considered in isolation, HDEs with higher levels of bioactivity were significantly associated with children who had lower numbers of positive SPT results. Analogous statistical analyses did not identify any association between HDE endotoxin levels and the aeroallergen sensitization profiles of children included in this study. HDE immunostimulatory activities predicted the aeroallergen sensitization status of CCAAPS subjects better than HDE endotoxin levels. These results provide the first published evidence that HDE bioassays have clinical relevance in predicting atopic risk. Copyright © 2012 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All

The prevalence of food allergy and other allergic diseases in early childhood in a population-based study: HealthNuts age 4-year follow-up.

Science.gov (United States)

Peters, Rachel L; Koplin, Jennifer J; Gurrin, Lyle C; Dharmage, Shyamali C; Wake, Melissa; Ponsonby, Anne-Louise; Tang, Mimi L K; Lowe, Adrian J; Matheson, Melanie; Dwyer, Terence; Allen, Katrina J

2017-07-01

The HealthNuts study previously reported interim prevalence data showing the highest prevalence of challenge-confirmed food allergy in infants internationally. However, population-derived prevalence data on challenge-confirmed food allergy and other allergic diseases in preschool-aged children remain sparse. This study aimed to report the updated prevalence of food allergy at age 1 year from the whole cohort, and to report the prevalence of food allergy, asthma, eczema, and allergic rhinitis at age 4 years. HealthNuts is a population-based cohort study with baseline recruitment of 5276 one-year-old children who underwent skin prick test (SPT) to 4 food allergens and those with detectable SPT results had formal food challenges. At age 4 years, parents completed a questionnaire (81.3% completed) and those who previously attended the HealthNuts clinic at age 1 year or reported symptoms of a new food allergy were invited for an assessment that included SPT and oral food challenges. Data on asthma, eczema, and allergic rhinitis were captured by validated International Study of Asthma and Allergies in Childhood questionnaires. The prevalence of challenge-confirmed food allergy at age 1 and 4 years was 11.0% and 3.8%, respectively. At age 4 years, peanut allergy prevalence was 1.9% (95% CI, 1.6% to 2.3%), egg allergy was 1.2% (95% CI, 0.9% to 1.6%), and sesame allergy was 0.4% (95% CI, 0.3% to 0.6%). Late-onset peanut allergy at age 4 years was rare (0.2%). The prevalence of current asthma was 10.8% (95% CI, 9.7% to 12.1%), current eczema was 16.0% (95% CI, 14.7% to 17.4%), and current allergic rhinitis was 8.3% (95% CI, 7.2% to 9.4%). Forty percent to 50% of this population-based cohort experienced symptoms of an allergic disease in the first 4 years of their life. Although the prevalence of food allergy decreased between age 1 year and age 4 years in this population-based cohort, the prevalence of any allergic disease among 4-year-old children in Melbourne

Measurements of the branching fractions for D+→KS0KS0K+, KS0KS0π+ and D0→KS0KS0, KS0KS0KS0

Directory of Open Access Journals (Sweden)

M. Ablikim

2017-02-01

Full Text Available By analyzing 2.93fb−1 of data taken at the ψ(3770 resonance peak with the BESIII detector, we measure the branching fractions for the hadronic decays D+→KS0KS0K+, D+→KS0KS0π+, D0→KS0KS0 and D0→KS0KS0KS0. They are determined to be B(D+→KS0KS0K+=(2.54±0.05stat.±0.12sys.×10−3, B(D+→KS0KS0π+=(2.70±0.05stat.±0.12sys.×10−3, B(D0→KS0KS0=(1.67±0.11stat.±0.11sys.×10−4 and B(D0→KS0KS0KS0=(7.21±0.33stat.±0.44sys.×10−4, where the second one is measured for the first time and the others are measured with significantly improved precision over the previous measurements.

FACT prevents the accumulation of free histones evicted from transcribed chromatin and a subsequent cell cycle delay in G1.

Directory of Open Access Journals (Sweden)

Macarena Morillo-Huesca

2010-05-01

Full Text Available The FACT complex participates in chromatin assembly and disassembly during transcription elongation. The yeast mutants affected in the SPT16 gene, which encodes one of the FACT subunits, alter the expression of G1 cyclins and exhibit defects in the G1/S transition. Here we show that the dysfunction of chromatin reassembly factors, like FACT or Spt6, down-regulates the expression of the gene encoding the cyclin that modulates the G1 length (CLN3 in START by specifically triggering the repression of its promoter. The G1 delay undergone by spt16 mutants is not mediated by the DNA-damage checkpoint, although the mutation of RAD53, which is otherwise involved in histone degradation, enhances the cell-cycle defects of spt16-197. We reveal how FACT dysfunction triggers an accumulation of free histones evicted from transcribed chromatin. This accumulation is enhanced in a rad53 background and leads to a delay in G1. Consistently, we show that the overexpression of histones in wild-type cells down-regulates CLN3 in START and causes a delay in G1. Our work shows that chromatin reassembly factors are essential players in controlling the free histones potentially released from transcribed chromatin and describes a new cell cycle phenomenon that allows cells to respond to excess histones before starting DNA replication.

Diffraction-based overlay for spacer patterning and double patterning technology

Science.gov (United States)

Lee, Byoung Hoon; Park, JeongSu; Lee, Jongsu; Park, Sarohan; Lim, ChangMoon; Yim, Dong-Gyu; Park, Sungki; Ryu, Chan-Ho; Morgan, Stephen; van de Schaar, Maurits; Fuchs, Andreas; Bhattacharyya, Kaustuve

2011-03-01

Overlay performance will be increasingly important for Spacer Patterning Technology (SPT) and Double Patterning Technology (DPT) as various Resolution Enhancement Techniques are employed to extend the resolution limits of lithography. Continuous shrinkage of devices makes overlay accuracy one of the most critical issues while overlay performance is completely dependent on exposure tool. Image Based Overlay (IBO) has been used as the mainstream metrology for overlay by the main memory IC companies, but IBO is not suitable for some critical layers due to the poor Tool Induced Shift (TIS) values. Hence new overlay metrology is required to improve the overlay measurement accuracy. Diffraction Based Overlay (DBO) is regarded to be an alternative metrology to IBO for more accurate measurements and reduction of reading errors. Good overlay performances of DBO have been reported in many articles. However applying DBO for SPT and DPT layers poses extra challenges for target design. New vernier designs are considered for different DPT and SPT schemes to meet overlay target in DBO system. In this paper, we optimize the design of the DBO target and the performance of DBO to meet the overlay specification of sub-3x nm devices which are using SPT and DPT processes. We show that the appropriate vernier design yields excellent overlay performance in residual and TIS. The paper also demonstrated the effects of vernier structure on overlay accuracy from SEM analysis.

Economic contribution of draught animals to Mazahua smallholder Campesino farming systems in the highlands of Central Mexico.

Science.gov (United States)

Arriaga-Jordán, C M; Pedraza-Fuentes, A M; Velázquez-Beltrán, L G; Nava-Bernal, E G; Chávez-Mejía, M C

2005-10-01

The economic contribution of draught animals to smallholder Mazahua campesino systems in two mountain villages of San Felipe del Progreso, in the central highlands of Mexico, was assessed. Campesinos rely on draught animals for cultivation tasks, as pack animals, and as transport for agricultural and domestic activities. The villages were San Pablo Tlalchichilpa (SPT) and La Concepción Mayorazgo (LCM). Twelve households that possessed draught animals were monitored from July 1999 to June 2000, nine in SPT and three in LCM, in terms of animal inventories and income from their draught animals, in cash and opportunity values. Equines in SPT have substituted bulls, and are recognized for their multipurpose contribution, while in LCM bulls are still used for ploughing the land. Overall total mean gross income was US dollar 490.78 per farm per year, plus US dollar 56 as opportunity value of the fertilizer value of manure for both villages. Deducting estimated costs, owning draught animals leaves a mean net margin of US dollar 412.50/year in SPT and of US dollar 285.64/year in LCM. There is a significant correlation (p draught animals and incomes, with a regression coefficient of US dollar 279.16 per year per draught animal. Besides positive economic returns, having work animals alleviates drudgery for the campesino families.

Longitudinal supportive periodontal therapy for severe chronic periodontitis with furcation involvement: a 12-year follow-up report.

Science.gov (United States)

Komiya-Ito, Akiyo; Tomita, Sachiyo; Kinumatsu, Takashi; Fujimoto, Yoshihiro; Tsunoda, Masatake; Saito, Atsushi

2013-01-01

We report a case involving a 12-year follow-up after treatment for chronic periodontitis with furcation involvement. A 54-year-old woman presented with the chief complaint of hypersensitivity. Clinical examination at the first visit revealed 15% of sites with a probing depth ≥4 mm and 35% of sites with bleeding on probing. Initial periodontal therapy was implemented based on a clinical diagnosis of severe chronic periodontitis. Surgical periodontal therapy was subsequently performed at selected sites. For #44, regenerative periodontal therapy using enamel matrix derivative (Emdogain(®)) was selected. For #16, which exhibited a 2- to 3-wall vertical bony defect and class III (mesio-distal) furcation involvement, bone graft was scheduled. Other sites with residual periodontal pockets were treated by open flap debridement. For #37, with a gutter-shaped root, odontoplasty was performed. After reevaluation, the patient was placed on supportive periodontal therapy (SPT). During 12 years of SPT, the periodontal condition remained uneventful in most of the teeth. However, bone resorption was observed in the distal aspect of #37, making the prognosis poor. This indicates the need to continuously monitor risk factors, including inflammation and traumatic occlusion, during SPT. Although some problems still remain, severe periodontitis with furcation involvement was successfully maintained longitudinally with an adequate level of patient compliance and careful SPT.

Deoxysphingoid bases as plasma markers in Diabetes mellitus

OpenAIRE

Bertea, Mariana; R?tti, Markus F; Othman, Alaa; Marti-Jaun, Jaqueline; Hersberger, Martin; von Eckardstein, Arnold; Hornemann, Thorsten

2010-01-01

Abstract Background Sphingoid bases are formed from the precursors L-serine and palmitoyl-CoA-a reaction which is catalyzed by the serine-palmitoyltransferase (SPT). SPT metabolizes, besides palmitoyl-CoA also other acyl-CoAs but shows also variability towards the use of other amino acid substrates. The enzyme is also able to metabolize alanine, which results in the formation of an atypical deoxy-sphingoid base (DSB). This promiscuous activity is greatly increased in the case of the sensory n...

Hall effect thruster with an AlN chamber

International Nuclear Information System (INIS)

Barral, S.; Jayet, Y.; Mazouffre, S.; Veron, E.; Echegut, P.; Dudeck, M.

2005-01-01

The plasma discharge of a Hall-effect thruster (SPT) is strongly depending of the plasma-insulated wall interactions. These interactions are mainly related to the energy deposition, potential sheath effect and electron secondary emission rate (e.s.e.). In usual SPT, the annular channel is made of BN-SiO 2 . The SPT100-ML (laboratory model will be tested with an AlN chamber in the French test facility Pivoine in the laboratoire d'Aerothermique (Orleans-France). The different parameters such as discharge current, thrust, plasma oscillations and wall temperature will studied for several operating conditions. The results will be compared with a fluid model developed in IPPT (Warsaw-Poland) taking into account electron emission from the internal and external walls and using previous experimental measurements of e.s.e. for AlN from ONERA (Toulouse-France). The surface state of AlN will be analysed before and after experiments by an Environmental Scanning Electron Microscope and by a Strength Electron Microscope. (author)

Nonablative Fractional Laser Resurfacing for Acne Scarring in Patients With Fitzpatrick Skin Phototypes IV-VI.

Science.gov (United States)

Alexis, Andrew F; Coley, Marcelyn K; Nijhawan, Rajiv I; Luke, Janiene D; Shah, Sejal K; Argobi, Yahya A; Nodzenski, Michael; Veledar, Emir; Alam, Murad

2016-03-01

There is a paucity of studies investigating laser resurfacing in Fitzpatrick skin phototypes (SPT) IV to VI. To assess the efficacy and safety of fractional nonablative laser resurfacing in the treatment of acne scarring in patients with SPT IV to VI. The authors conducted a randomized, investigator-blinded and rater-blinded, split-face comparative study of adults with SPT IV to VI and facial acne scars treated with 2 different density settings and the same fluence. Quantitative global scarring grading system (QGSGS) scores were significantly improved from baseline at 16 and 24 weeks (p = .0277). Improvements in QGSGS scores after higher and lower density treatments were statistically similar (p = .96). The live-blinded dermatologist, the blinded dermatologist photoraters, and the patients rated scars as being significantly more improved by visual analog scale at weeks 16 and 24 compared with baseline (p skin types IV to VI. Self-limited postinflammatory hyperpigmentation was a common occurrence, especially with higher treatment densities.

A perturbative approach to the redshift space power spectrum: beyond the Standard Model

Energy Technology Data Exchange (ETDEWEB)

Bose, Benjamin; Koyama, Kazuya, E-mail: benjamin.bose@port.ac.uk, E-mail: kazuya.koyama@port.ac.uk [Institute of Cosmology and Gravitation, University of Portsmouth, Burnaby Road, Portsmouth, Hampshire, PO1 3FX (United Kingdom)

2016-08-01

We develop a code to produce the power spectrum in redshift space based on standard perturbation theory (SPT) at 1-loop order. The code can be applied to a wide range of modified gravity and dark energy models using a recently proposed numerical method by A.Taruya to find the SPT kernels. This includes Horndeski's theory with a general potential, which accommodates both chameleon and Vainshtein screening mechanisms and provides a non-linear extension of the effective theory of dark energy up to the third order. Focus is on a recent non-linear model of the redshift space power spectrum which has been shown to model the anisotropy very well at relevant scales for the SPT framework, as well as capturing relevant non-linear effects typical of modified gravity theories. We provide consistency checks of the code against established results and elucidate its application within the light of upcoming high precision RSD data.

Small-scale Specimen Testing of Monolithic U-Mo Fuel Foils

Energy Technology Data Exchange (ETDEWEB)

Ramprashad Prabhakaran; Douglas E. Burkes; James I. Cole; Indrajit Charit; Daniel M. Wachs

2008-10-01

The objective of this investigation is to develop a shear punch testing (SPT) procedure and standardize it to evaluate the mechanical properties of irradiated fuels in a hot-cell so that the tensile behavior can be predicted using small volumes of material and at greatly reduced irradiation costs. This is highly important in the development of low-enriched uranium fuels for nuclear research and test reactors. The load-displacement data obtained using SPT can be interpreted in terms of and correlated with uniaxial mechanical properties. In order to establish a correlation between SPT and tensile data, sub-size tensile and microhardness testing were performed on U-Mo alloys. In addition, efforts are ongoing to understand the effect of test parameters (such as specimen thickness, surface finish, punch-die clearance, crosshead velocity and carbon content) on the measured mechanical properties, in order to rationalize the technique, prior to employing it on a material of unknown strength.

Small-scale Specimen Testing of Monolithic U-Mo Fuel Foils

International Nuclear Information System (INIS)

Ramprashad Prabhakaran; Douglas E. Burkes; James I. Cole; Indrajit Charit; Daniel M. Wachs

2008-01-01

The objective of this investigation is to develop a shear punch testing (SPT) procedure and standardize it to evaluate the mechanical properties of irradiated fuels in a hot-cell so that the tensile behavior can be predicted using small volumes of material and at greatly reduced irradiation costs. This is highly important in the development of low-enriched uranium fuels for nuclear research and test reactors. The load-displacement data obtained using SPT can be interpreted in terms of and correlated with uniaxial mechanical properties. In order to establish a correlation between SPT and tensile data, sub-size tensile and microhardness testing were performed on U-Mo alloys. In addition, efforts are ongoing to understand the effect of test parameters (such as specimen thickness, surface finish, punch-die clearance, crosshead velocity and carbon content) on the measured mechanical properties, in order to rationalize the technique, prior to employing it on a material of unknown strength

Baker's asthma in a child.

Science.gov (United States)

Alonso, E; Ausín, A; Elices, A; Moreno-Escobosa, M; Ibáñez, M; Laso, M

2001-01-01

baker's asthma is a well-known occupational lung disease which usually develops in adults. We report the case of a two years old boy who suffered from asthma, urticaria and atopic dermatitis for twelve months, whose symptoms were associated to visits to his grandfather's bakery. skin prick tests (SPT) were made to dust mites, moulds, flours, alfa-amylase and egg. It was also determined total IgE and specific IgE antibodies to alfa-amylase and flours. Subsequently, a challenge test was carried out with wheat flour. The SPTs were positive to flours, alfa-amylase and egg. The determination of specific IgE antibodies showed 2.64 kU/L to wheat, 0.79 kU/L to glyadin and 2.98 kU/L to alfa-amylase. The patient developed asthma and rhinitis after manipulating wheat flour for 10 min. we demonstrated a type I hypersensitivity to wheat flour and alfa-amylase in a two years old child by SPT, specific IgE antibodies and challenge test. This case in the childhood equivalent of occupational baker's asthma.

MODELO DE INTERPOLACIÓN ESPACIAL MEDIANTE SISTEMAS DE INFORMACIÓN GEOGRÁFICA PARA EL ESTUDIO DE LA VARIABILIDAD ESPACIAL DE LA RESISTENCIA A LA PENETRACIÓN DEL SUELO

Directory of Open Access Journals (Sweden)

LIBARDO ANTONIO LONDOÑO CIRO

2010-01-01

Full Text Available Entre 1993 y 2005, se han realizado numerosos estudios de suelos en un amplio sector del barrio Laureles (Medellín, Departamento de Antioquia, Colombia, que han tenido como objeto la identificación de la estratigrafía de la zona y la determinación de la capacidad portante del suelo. Los ensayos de campo y laboratorio realizados durante estas exploraciones son resistencia a la penetración estándar (Standar Penetration Test SPT y ensayos de laboratorio de resistencia a la compresión simple. A estos datos se les realizó un proceso de georeferenciación para profundidades especificas de 2.5, 5.0 y 7.5 metros para el ensayo SPT, y 2.30 y 3.30 metros para los ensayos de compresión simple. Mediante el uso de técnicas geoestadísticas (interpolación espacial, se modelaron superficies para el área en estudio, con el propósito de encontrar información en locaciones en las cuales no se han realizado estudios de suelos.

Growing season temperature and precipitation variability and extremes in the U.S. Corn Belt from 1981 to 2012

Science.gov (United States)

Dai, S.; Shulski, M.

2013-12-01

Climate warming and changes in rainfall patterns and increases in extreme events are resulting in higher risks of crop failures. A greater sense of urgency has been induced to understand the impacts of past climate on crop production in the U.S. As one of the most predominant sources of feed grains, corn is also the main source of U.S. ethanol. In the U.S. Corn Belt, region-scale evaluation on temperature and precipitation variability and extremes during the growing season is not well-documented yet. This study is part of the USDA-funded project 'Useful to Usable: Transforming climate variability and change information for cereal crop producers'. The overall goal of our work is to study the characteristics of average growing season conditions and changes in growing season temperature- and precipitation-based indices that are closely correlated with corn grain yield in the U.S. Corn Belt. The research area is the twelve major Corn Belt states, including IL, IN, IA, KS, MI, MN, MO, NE, OH, SD, ND, and WI. Climate data during 1981-2010 from 132 meteorological stations (elevation ranges from 122 m to 1,202 m) are used in this study, including daily minimum, maximum, and mean temperature, and daily precipitation. From 1981 to 2012, beginning date (BD), ending date (ED), and growing season length (GSL) in the climatological corn growing season are studied. Especially, during the agronomic corn growing season, from Apr to Oct, temperature- and precipitation-based indices are analyzed. The temperature-based indices include: number of days with daily mean temperature below 10°C, number of days with daily mean temperature above 30°C, the sum of growing degree days (GDD) between 10°C to 30°C (GDD10,30, growth range for corn), the sum of growing degree days above 30°C (GDD30+, exposure to harmful warming for corn), the sum of growing degree days between 0°C and 44°C (GDD0,44, survival range limits for corn), the sum of growing degree days between 5°C and 35°C (GDD5

Significance of determination of female sex hormones (E2, LH, FSH), insulin-like growth factor I (IGF-I) and leptin in girls with precocious puberty

International Nuclear Information System (INIS)

Huang Jianrong

2004-01-01

Objective: To investigate the diagnostic value of determination of serum levels of estradiol (E 2 ), luteinizing hormone (LH) and follicle stimulating hormone (FSH), insulin-like growth factor (IGF-I) and leptin in girls with idiopathic central precocious puberty (ICPP). Methods: Serum E 2 , LH, FSH, IGF-I (with chemiluminescence immunoassay) and leptin (with RIA) levels were determined in 35 girls with early development of breast as the sign of precocious puberty, of which, 15 was considered to be of the ICPP group and 20 of simple premature thelarche group (SPT). Criteria of diagnosis for ICPP were: peak LH value>12IU/L and LH/FSH>1 after GnRH stimulating test. Results: Serum E 2 , LH, FSH, IGF-I leptin levels in girls with ICPP were significantly higher than those in the girls with SPT (P 0.2 as the cut-off value for diagnosis of ICPP there would still be a positive rate of 86.6% suggesting that the diagnostic criteria might be set lower. Serum IGF-I levels were positively correlated to those of E 2 (r=0.47, P 2 and IGF-I. Conclusion: Determinations of serum E 2 , LH, FHS, IGF-I and leptin levels were helpful for the early diagnosis of ICPP. (author)

Proceedings of the 17th Conference on Toxicology Held in Dayton, Ohio on 3-5 November 1987

Science.gov (United States)

1989-09-01

criterional stability. PEST was developed by Taylor and Creelman [35] and has been revisited on several occasions since [36-41]. 366 >0 0 . 0 0 c- L9 . 0...Psychol. 18, 1-10. 35 Taylor, M.M. and Creelman , C.D. (1967) PEST: Efficient estimates on probablity functions J. Accoust. Soc. Am. 41, 782-787. 36

Factors related to allergic sensitization to aeroallergens in a cross-sectional study in adults

DEFF Research Database (Denmark)

Linneberg, A; Nielsen, N H; Madsen, F

2001-01-01

number of siblings, a positive family history of hay fever and never smoking, were independently associated with both SPT positivity and specific IgE positivity. Furthermore, SPT positivity was positively associated with alcohol consumption (dose-response relationship only), and negatively associated......-response relationship. CONCLUSION: Being male, young age, a positive family history of hayfever, low number of siblings and never smoking, were independently associated with allergic sensitization. In addition, the results indicated a possible relationship of alcohol consumption, body mass index and previous keeping...

Can we see scalar, pseudoscalar or tensor interactions in coherent pion production?

International Nuclear Information System (INIS)

Rein, D.

1988-01-01

The possibility to detect nonconventional scalar, pseudoscalar or tensor interactions (SPT) in the angular distribution of pions produced coherently in neutrino nucleus reactions is reexamined. It is found that the angular distribution does not differ qualitatively from a corresponding distribution arising from conventional vector-axial vector (VA) interactions unless the energy of the outgoing pion is restricted. Even then SPT interactions are likely to be overshadowed by transverse VA interactions which can mimic the former at finite although small momentum transfer Q 2 . (author)

Preparation and electrochemical properties of La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 (x = 0, 0.30, 0.33, 0.36, 0.39) hydrogen storage alloys

International Nuclear Information System (INIS)

Tian, Xiao; Wei, Wei; Duan, Ruxia; Zheng, Xinyao; Zhang, Huaiwei; Tegus, O.; Li, Xingguo

2016-01-01

The as-cast alloy with the composition of La_0_._7_0Ni_2_._4_5Co_0_._7_5Al_0_._3_0 was prepared by vacuum arc melting. La–Mg–Ni-based La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 hydrogen storage alloy has been synthesized by high-energy vibratory milling blending of the La_0_._7_0Ni_2_._4_5Co_0_._7_5Al_0_._3_0 as-cast alloy and elemental Mg, followed by an isothermal annealing. The microstructures and electrochemical properties of the La_0_._7_0Ni_2_._4_5Co_0_._7_5Al_0_._3_0 and La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 alloys were investigated by XRD, SEM and electrochemical measurements. The XRD analysis and Rietveld refinement showed that the as-cast La_0_._7_0Ni_2_._4_5Co_0_._7_5Al_0_._3_0 alloy consists of single LaNi_5 phase, whereas the La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 alloys contain the LaNi_5 and (La, Mg)_2Ni_7. The electrochemical measurements indicated that the maximum discharge capacity and discharge potential characteristic of the La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 alloys increases first and then decreases with increasing x. The maximum discharge capacity and discharge potential characteristic of alloy reaches the optimum when x is 0.36. The cyclic stability of the La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 alloy with a smaller quantity of Mg is better than that of the alloy with a larger quantity of Mg. - Highlights: • La–Mg–Ni-based alloy was synthesized by melting, milling and subsequent annealing. • Mg atoms exist in the La_2Ni_7 phase prior to LaNi_5 phase. • The La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 alloys consist of the LaNi_5 and (La, Mg)_2Ni_7. • The more Mg element the alloys contain, the easier aggregation Mg atom is. • The C_m_a_x of La_0_._7_0Mg_xNi_2_._4_5Co_0_._7_5Al_0_._3_0 alloy first increases and then decreases with rising x.

Decree N0 73-322 of 15 March 1973 concerning insurance and reinsurance of exceptional and nuclear risks by the Central Reinsurance Fund

International Nuclear Information System (INIS)

1973-01-01

This Decree provides that the Central Reinsurance Fund may cover, with the State guarantee, risks for which operators of nuclear ships and installations are liable and concerning which State intervention is provided for by legislation. These operations relate in particular to goods carried, nuclear installations and property on the site of such installations. The Decree sets up an Advisory Commission for the Central Reinsurance Fund regarding security for exceptional and nuclear risks and repeals a 1967 Decree on insurance of exceptional risks. (NEA) [fr

High Temperature Deformation Mechanisms in a DLD Nickel Superalloy

Directory of Open Access Journals (Sweden)

Sean Davies

2017-04-01

Full Text Available The realisation of employing Additive Layer Manufacturing (ALM technologies to produce components in the aerospace industry is significantly increasing. This can be attributed to their ability to offer the near-net shape fabrication of fully dense components with a high potential for geometrical optimisation, all of which contribute to subsequent reductions in material wastage and component weight. However, the influence of this manufacturing route on the properties of aerospace alloys must first be fully understood before being actively applied in-service. Specimens from the nickel superalloy C263 have been manufactured using Powder Bed Direct Laser Deposition (PB-DLD, each with unique post-processing conditions. These variables include two build orientations, vertical and horizontal, and two different heat treatments. The effects of build orientation and post-process heat treatments on the materials’ mechanical properties have been assessed with the Small Punch Tensile (SPT test technique, a practical test method given the limited availability of PB-DLD consolidated material. SPT testing was also conducted on a cast C263 variant to compare with PB-DLD derivatives. At both room and elevated temperature conditions, differences in mechanical performances arose between each material variant. This was found to be instigated by microstructural variations exposed through microscopic and Energy Dispersive X-ray Spectroscopy (EDS analysis. SPT results were also compared with available uniaxial tensile data in terms of SPT peak and yield load against uniaxial ultimate tensile and yield strength.

Analysis of the existing correlations of effective friction angle for eastern piedmont soils of Bogota from in situ tests

Directory of Open Access Journals (Sweden)

July E. Carmona-Álvarez

2015-07-01

Full Text Available To estimate the effective friction angle of soil from in situ test is a complicated job, due to high rates of strain existing in this kind of tests, which tend to be too invasive and disturb the vicinities of test depth, even the sample that eventually is taken at the site. Likewise, the most of the correlations found in the current bibliography to obtain the effective friction angle using field tests, have been developed for soils from different regions. For that reason when are implemented on tropical soils present high scatter, to compare the field parameter values with real results obtained at the lab. This research aims to use in situ tests define through of analysis of different correlations, which fits adequately to the specific conditions of the piedmont soils of Bogota. For the present study will be utilized data from SPT (widely used in Colombia and SPT-T (never before conducted in the country, carried out considering the appropriated norms to each test, taking in account to SPT-T, doesn’t exist local standard governing such tests. The correlations for field procedures of the tests implemented were for effective confining and energy transference of the SPT hammer, since the state-of-the-art mentions it as the most affect the reliability of the final results. The final results show the tendency of the methodologies used to obtain the correlation, in relation with the real value of effective friction angle from of lab tests.

Analysis of changes in the federal funding trends to higher education for basic research in space, solar, and nuclear sciences compared to government and industry: 1967-1985

International Nuclear Information System (INIS)

Veasey, C. Jr.

1985-01-01

The problem addressed by this study is that the amount of federal funds allocated in higher education for conducting basic research in space, solar, and nuclear sciences appear to be declining relative to government and industry. To test this hypothesis, data were obtained from the National Science Foundation on the amounts of federal funds provided for research and development from fiscal years 1955 to 1985. The NSF data were organized into tables, presented, and analyzed to help determine what changes had occurred in the amounts of federal funds allocated to higher education, government, and industry for basic research in space, solar, and nuclear sciences for fiscal years 1967 to 1985. The study provided six recommendations to augment declining federal funds for basic research. (1) Expand participation in applied research, (2) Develop and expand consortia arrangements with other academic institutions of higher education. (3) Pursue other funding sources such as alumni, private foundations, industry, and state and local government. (4) Develop and expand joint research with national and industrial laboratories. (5) Expand participation in interdisciplinary and multidisciplinary research to develop technological solutions to local, regional, and national problems. (6) Develop and expand programs of reciprocal internships, and sabbaticals with industrial and national laboratories

The effect of single and multiple infections on atopy and wheezing in children.

Science.gov (United States)

Alcantara-Neves, Neuza Maria; Veiga, Rafael Valente; Dattoli, Vitor Camilo Cavalcante; Fiaccone, Rosimeire Leovigildo; Esquivel, Renata; Cruz, Álvaro Augusto; Cooper, Philip John; Rodrigues, Laura Cunha; Barreto, Maurício Lima

2012-02-01

The current epidemic of asthma and atopy has been explained by alterations in immune responses related to reduction in childhood infections. However, the findings of epidemiologic studies investigating the association between infection with atopy and asthma have been inconsistent. We sought to investigate the effect of single or multiple infections (pathogen burden) on atopy and wheeze in urban children from Latin America. Specific IgE against aeroallergens (sIgE) and skin prick test (SPT) reactivity for the most common local allergens were measured in 1128 children aged 4 to 11 years. Data on wheezing and potential confounders were collected by questionnaire. Infections by 8 pathogens were assessed by using serology and stool examination. Associations of wheeze and atopic outcomes with single and multiple infections were analyzed by means of logistic regression. Negative results for Toxoplasma gondii were associated with a higher prevalence of sIgE (≥0.70 kU/L), whereas negative results for Ascaris lumbricoides, T gondii, herpes simplex virus, and EBV were associated with a higher prevalence of SPT reactivity. Children with 3 or fewer infection markers had a higher prevalence of sIgE and SPT reactivity compared with those with 4 or more infection markers. However, isolated infections or pathogen burden were not associated with the prevalence of atopic or nonatopic wheeze. The findings provide support for the idea that the hygiene hypothesis is operating in an urban Latin American context, but its expression is thus far restricted to the atopic status of patients and not the perceived asthma symptoms. Copyright © 2011 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

Estimating SPT-N Value Based on Soil Resistivity using Hybrid ANN-PSO Algorithm

Science.gov (United States)

Nur Asmawisham Alel, Mohd; Ruben Anak Upom, Mark; Asnida Abdullah, Rini; Hazreek Zainal Abidin, Mohd

2018-04-01

Standard Penetration Resistance (N value) is used in many empirical geotechnical engineering formulas. Meanwhile, soil resistivity is a measure of soil’s resistance to electrical flow. For a particular site, usually, only a limited N value data are available. In contrast, resistivity data can be obtained extensively. Moreover, previous studies showed evidence of a correlation between N value and resistivity value. Yet, no existing method is able to interpret resistivity data for estimation of N value. Thus, the aim is to develop a method for estimating N-value using resistivity data. This study proposes a hybrid Artificial Neural Network-Particle Swarm Optimization (ANN-PSO) method to estimate N value using resistivity data. Five different ANN-PSO models based on five boreholes were developed and analyzed. The performance metrics used were the coefficient of determination, R2 and mean absolute error, MAE. Analysis of result found that this method can estimate N value (R2 best=0.85 and MAEbest=0.54) given that the constraint, Δ {\\bar{l}}ref, is satisfied. The results suggest that ANN-PSO method can be used to estimate N value with good accuracy.

Correlation of cutaneous sensitivity and cytokine response in children with asthma

Directory of Open Access Journals (Sweden)

Meenu Singh

2017-01-01

Full Text Available Background: Food allergy occurs in a significant portion of pediatric asthma. Various cells and their mediators/cytokines play a pivotal role in orchestrating the airway inflammatory response in asthma. Objective: To study the cutaneous hypersensitivity, Th1, Th2, and Th17 response of pediatric population with asthma and genetic predisposition to atopy, by determining total immunoglobulin E (IgE level in response to various food allergens. Materials and Methods: Fifty asthmatic children with a history of worsening symptoms by various food allergens (study group and twenty healthy children (control group were included. Food allergy was assessed through skin prick test (SPT of various food allergens. Total serum IgE level was measured by sandwich ELISA, and T-cell (Th1, Th2, and Th17-dependent cytokines were measured by flow cytometry. Results: All 50 asthmatic children in the study group showed SPT positivity against various food allergens (rice = 17; banana, fish and groundnut = 10; wheat = 9; milk and orange = 7; egg = 6; and mango = 4. The average total IgE level in the study group was 316.8 ± 189.8 IU/mL. A significant positive correlation of total IgE with interleukin 17 (IL-17 (r = 0.796; P < 0.0001, IL-13 (r = 0.383; P = 0.01, and IL-4 (r = 0.263; P = 0.043 level was noted. A significant negative correlation of total IgE was noted with interferon gamma (r = −0.5823; P < 0.0001 and IL-10 (r = −0.4474; P < 0.001 level and the duration of breastfeeding (r = −0.31, P = 0.03. Conclusions: The present study found a positive correlation between total serum IgE level and Th2, Th17 cytokines in a pediatric population with asthma. A significant negative correlation was found between the duration of breastfeeding and the cytokines.

Feasibility and effectiveness of circuit training in acute stroke rehabilitation.

Science.gov (United States)

Rose, Dorian; Paris, Trevor; Crews, Erin; Wu, Samuel S; Sun, Anqi; Behrman, Andrea L; Duncan, Pamela

2011-02-01

Task-specificity, repetition and progression are key variables in the acquisition of motor skill however they have not been consistently implemented in post-stroke rehabilitation. To evaluate the effectiveness of a stroke rehabilitation plan of care that incorporated task-specific practice, repetition and progression to facilitate functional gain compared to standard physical therapy for individuals admitted to an inpatient stroke unit. Individuals participated in either a circuit training (CTPT) model (n = 72) or a standard (SPT) model (n = 108) of physical therapy, 5 days/week. Each 60 minute circuit training session, delivered according to severity level, consisted of four functional mobility tasks. Daily exercise logs documented both task repetition and progression. The CTPT model was successfully implemented in an acute rehabilitation setting. The CTPT group showed a significantly greater improved change in gait speed from hospital admission to discharge than the SPT group (0.21 ± 0.25 m/sec vs. 0.13 ± 0.22 m/sec; p = 0.03). The difference between groups occurred primarily among those who were ambulatory upon admission. There were no significant differences between the two cohorts at 90 days post-stroke as measured by the FONE-FIM, SF-36 and living location. Therapy focused on systematically progressed functional tasks can be successfully implemented in an inpatient rehabilitation stroke program. This circuit-training model resulted in greater gains in gait velocity over the course of inpatient rehabilitation compared to the standard model of care. Community-based services following hospital discharge to maintain these gains should be included in the continuum of post-stroke care.

International dictionary of geophysics : S. K. Runcorn (editor-in-chief). Pergamon, Oxford, 1967, 2 volumes, 1,728 pp., 730 fig., £ 45.0.0

NARCIS (Netherlands)

Manten, A.A.

1968-01-01

The reader is informed about a large number of subjects in a generally brief, elucidating manner. No single source contains such a large number of short review articles. That the general framework in which the contributions are contained is weak, is no reflection on the authors, but the

Use of the isotope flux ratio approach to investigate the C18O16O and 13CO2 exchange near the floor of a temperate deciduous forest

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P. Bartlett

2012-07-01

Full Text Available Stable isotopologues of CO2, such as 13CO2 and C18OO, have been used to study the CO2 exchange between land and atmosphere. The advent of new measuring techniques has allowed near-continuous measurements of stable isotopes in the air. These measurements can be used with micrometeorological techniques, providing new tools to investigate the isotope exchange in ecosystems. The objectives of this study were to evaluate the use of the isotope flux ratio method (IFR near the forest floor of a temperate deciduous forest and to study the temporal dynamics of δ18O of CO2 flux near the forest floor by comparing IFR estimates with estimates of δ18O of net soil CO2 flux provided by an analytical model. Mixing ratios of 12C16O2, 13CO2 and C16O18O were measured within and above a temperate deciduous forest, using the tunable diode laser spectroscopy technique. The half-hourly compositions of the CO2 flux near the forest floor (δ13CF and δ18OF were calculated by IFR and compared with estimates provided by a modified Keeling plot technique (mKP and by a Lagrangian dispersion analysis (WT analysis. The mKP and IFR δ18OF estimates showed good agreement (slope = 1.03 and correlation, R2 = 0.80. The δ13CF estimates from the two methods varied in a narrow range of −32.7 and −23‰; the mean (± SE mKP and IFR δ13CF values were −27.5‰ (±0.2 and −27.3‰ (±0.1, respectively, and were statistically identical (p>0.05. WT analysis and IFR δ18OF estimates showed better correlation (R2 = 0.37 when only turbulent periods (u*>0.6 m s−1 were included in the analysis. The large amount of data captured (~95 % of half-hour periods evaluated for the IFR in comparison with mKP (27 % shows that the former provides new opportunities for studying δ18OF dynamics within forest canopies. Values of δ18OF showed large temporal variation, with values ranging from −31.4‰ (DOY 208 to −11.2‰ (DOY 221. Precipitation events caused substantial variation (~8�

Análisis de los contenidos matemáticos en los libros de divulgación matemática

OpenAIRE

Rodríguez Rodríguez, Ángela María

2017-01-01

La realización de este trabajo de investigación se centra en el análisis de los contenidos matemáticos que existen en libros de divulgación matemática, por lo tanto la pregunta a la que doy respuesta es “¿Existen contenidos de geometría y medida para sexto curso de primaria en libros de divulgación matemática de secundaria?”. Para empezar, debía acotar el campo de estudio, tanto en curso como en contenidos. El curso elegido fue sexto de primaria, por tener algunos contenidos relacionados c...

Política externa como política pública: uma análise pela regulamentação constitucional brasileira (1967-1988

Directory of Open Access Journals (Sweden)

Michelle Ratton Sanchez

2006-11-01

Full Text Available O objetivo deste trabalho é relacionar os debates sobre política externa e política pública, a partir de uma perspectiva constitucional. Para afastar o consenso de que a política externa sempre foi considerada como "externa" aos estados e distinta de toda e qualquer política doméstica - e assim de toda e qualquer política pública -, buscou-se identificar as políticas interna, externa e internacional como um continuum de um mesmo processo decisório. A partir desses pressupostos teóricos, apresentou-se uma análise da distribuição de competências da política externa brasileira nas constituições de 1967 e 1988, com o intuito de identificar, no contexto de redemocratização do Brasil possíveis alterações na regulamentação da política externa que sugerissem a incorporação de uma concepção de gestão poliárquica, que a aproximasse das demais políticas públicas. Por fim, compararam-se os mecanismos disponíveis na Constituição de 1988 para o controle da política externa e das políticas públicas em geral, a fim de proceder-se à sua aproximação e verificar a aplicabilidade dos mecanismos relativos às políticas públicas para controle da política externa.

AcEST: DK943548 [AcEST

Lifescience Database Archive (English)

Full Text Available astX Result : Swiss-Prot sp_hit_id Q9Y2K1 Definition sp|Q9Y2K1|ZBTB1_HUMAN Zinc finger and BTB domain-contai......done Score E Sequences producing significant alignments: (bits) Value sp|Q9Y2K1|ZBTB1_HUMAN Zinc finger a...6.3 sp|Q9DDT5|SPT5H_DANRE Transcription elongation factor SPT5 OS=Da... 29 8.2 >sp|Q9Y2K1|ZBTB1_HUMAN Zinc f

[A case of mixed connective tissue disease positive for proteinase 3 antineutrophil cytoplasmic antibody in a patient with slowly progressive type 1 diabetes mellitus and chronic thyroiditis].

Science.gov (United States)

Michitsuji, Tohru; Horai, Yoshiro; Sako, Ayaka; Asano, Taro; Iwanaga, Nozomi; Izumi, Yasumori; Kawakami, Atsushi

2017-01-01

  A female in her sixties with slowly progressive type 1 diabetes mellitus (SPT1DM) and chronic thyroiditis was referred to our rheumatology department with swelling in her fingers. A prominent atherosclerotic lesion was revealed upon brain magnetic resonance imaging, and she was found to have mixed connective tissue disease (MCTD) positive for proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA). This rare case of MCTD accompanying SPT1DM and PR3-ANCA suggested that a synergy between MCTD and PR3-ANCA triggers atherosclerosis.

Anther development stage and gamma radiation effects on tomato anther-derived callus formation; Efeitos do estadio de desenvolvimento da antera e da radiacao gama na formacao de calos derivados de anteras de tomate

Energy Technology Data Exchange (ETDEWEB)

Brasileiro, Ana Christina R.; Willadino, Lilia [Universidade Federal Rural de Pernambuco, Recife, PE (Brazil). Lab. de Cultura de Tecidos Vegetais. E-mail: lilia@truenet.com.br; Guerra, Marcelo [Pernambuco Univ., Recife, PE (Brazil). Dept. de Botanica. Lab. de Citogenetica Vegetal; Colaco, Waldeciro [Pernambuco Univ., Recife, PE (Brazil). Dept. de Energia Nuclear. Lab. de Radioagronomia; Meunier, Isabelle [Universidade Federal Rural de Pernambuco, Recife, PE (Brazil). Dept. de Engenharia Florestal; Camara, Terezinha R. [Universidade Federal Rural de Pernambuco, Recife, PE (Brazil). Dept. de Quimica. Lab. de Cultura de Tecidos Vegetais

1999-12-01

Two experiments were carried (I) to determine tomato anther development stage influence on callus production; and (II) to investigate gamma radiation effects on anther culture. In the first experiment, anthers of a tomato hybrid (IPA 5 x Rotam 4-F{sub 1}) were grown on three media. Although calli were induced at all stages of anther development, varying from prophase I to mono nucleate microspore, callus frequency decreased as anther development progressed and calli induction were not significantly affected by all media tested. Anthers containing prophase I meiocytes produced the highest calli frequency. Anther and flower bud length both were significantly correlated with anther development stage. In the second experiment, seed and floral buds of tomato hybrids IPA 5 x Rotam 4 (F{sub 2}), IPA 6 x Rotam 4 (F{sub 2}) and IPA 8 x 217.1 (F{sub 2}) were submitted to gamma-ray and anthers were plated on two media described by Gresshoff and Doy (1972) supplemented with 2.0 mg L{sup -1} NAA + 5.0 mg L{sup -1} KIN and 2.0 mg L{sup -1} NAA + 1.0 mg L{sup -1} KIN. No significant differences for genotype and dosage testes were found for calli formation. (author)

Spina bifida and cleft lip among newborns of Norwegian women with epilepsy: changes related to the use of anticonvulsants.

Science.gov (United States)

King, P B; Lie, R T; Irgens, L M

1996-01-01

OBJECTIVES: This study examined the connection between the use of anticonvulsants for epilepsy during or before pregnancy and the risk of spina bifida and cleft lip in newborns. METHODS: Among mothers registered from 1967 to 1992 by the Medical Birth Registry of Norway, 7588 who had epilepsy were identified and their newborns' prevalence of spina bifida and cleft lip examined. RESULTS: The odds ratio of spina bifida in children of mothers with epilepsy compared with other children increased from 1.5 in 1967 through 1980 (95% confidence interval [CI] = 0.3, 4.5) to 4.4 in 1981 through 1992 (95% CI = 2.0, 8.5). The odds ratio of cleft lip, however, decreased from 3.0 before 1981 (95% CI = 1.6, 5.1) to 1.1 after 1981 (95% CI = 0.4, 2.3). CONCLUSIONS: This shift toward more serious birth defects is consistent with the different teratogenic effects of newer and older anticonvulsants. PMID:8876519

The Effect of Three-Monthly Albendazole Treatment on Malarial Parasitemia and Allergy: A Household-Based Cluster-Randomized, Double-Blind, Placebo-Controlled Trial

Science.gov (United States)

Kaisar, Maria M. M.; May, Linda; Prasetyani, Margaretta A.; Wahyuni, Sitti; Djuardi, Yenny; Ariawan, Iwan; Wibowo, Heri; Lell, Bertrand; Sauerwein, Robert; Brice, Gary T.; Sutanto, Inge; van Lieshout, Lisette; de Craen, Anton J. M.; van Ree, Ronald; Verweij, Jaco J.; Tsonaka, Roula; Houwing-Duistermaat, Jeanine J.; Luty, Adrian J. F.; Sartono, Erliyani; Supali, Taniawati; Yazdanbakhsh, Maria

2013-01-01

Background Helminth infections are proposed to have immunomodulatory activities affecting health outcomes either detrimentally or beneficially. We evaluated the effects of albendazole treatment, every three months for 21 months, on STH, malarial parasitemia and allergy. Methods and Findings A household-based cluster-randomized, double-blind, placebo-controlled trial was conducted in an area in Indonesia endemic for STH. Using computer-aided block randomization, 481 households (2022 subjects) and 473 households (1982 subjects) were assigned to receive placebo and albendazole, respectively, every three months. The treatment code was concealed from trial investigators and participants. Malarial parasitemia and malaria-like symptoms were assessed in participants older than four years of age while skin prick test (SPT) to allergens as well as reported symptoms of allergy in children aged 5–15 years. The general impact of treatment on STH prevalence and body mass index (BMI) was evaluated. Primary outcomes were prevalence of malarial parasitemia and SPT to any allergen. Analysis was by intention to treat. At 9 and 21 months post-treatment 80.8% and 80.1% of the study subjects were retained, respectively. The intensive treatment regiment resulted in a reduction in the prevalence of STH by 48% in albendazole and 9% in placebo group. Albendazole treatment led to a transient increase in malarial parasitemia at 6 months post treatment (OR 4.16(1.35–12.80)) and no statistically significant increase in SPT reactivity (OR 1.18(0.74–1.86) at 9 months or 1.37 (0.93–2.01) 21 months). No effect of anthelminthic treatment was found on BMI, reported malaria-like- and allergy symptoms. No adverse effects were reported. Conclusions The study indicates that intensive community treatment of 3 monthly albendazole administration for 21 months over two years leads to a reduction in STH. This degree of reduction appears safe without any increased risk of malaria or allergies. Trial

Image Restoration and Analysis of Influenza Virions Binding to Membrane Receptors Reveal Adhesion-Strengthening Kinetics.

Directory of Open Access Journals (Sweden)

Donald W Lee

Full Text Available With the development of single-particle tracking (SPT microscopy and host membrane mimics called supported lipid bilayers (SLBs, stochastic virus-membrane binding interactions can be studied in depth while maintaining control over host receptor type and concentration. However, several experimental design challenges and quantitative image analysis limitations prevent the widespread use of this approach. One main challenge of SPT studies is the low signal-to-noise ratio of SPT videos, which is sometimes inevitable due to small particle sizes, low quantum yield of fluorescent dyes, and photobleaching. These situations could render current particle tracking software to yield biased binding kinetic data caused by intermittent tracking error. Hence, we developed an effective image restoration algorithm for SPT applications called STAWASP that reveals particles with a signal-to-noise ratio of 2.2 while preserving particle features. We tested our improvements to the SPT binding assay experiment and imaging procedures by monitoring X31 influenza virus binding to α2,3 sialic acid glycolipids. Our interests lie in how slight changes to the peripheral oligosaccharide structures can affect the binding rate and residence times of viruses. We were able to detect viruses binding weakly to a glycolipid called GM3, which was undetected via assays such as surface plasmon resonance. The binding rate was around 28 folds higher when the virus bound to a different glycolipid called GD1a, which has a sialic acid group extending further away from the bilayer surface than GM3. The improved imaging allowed us to obtain binding residence time distributions that reflect an adhesion-strengthening mechanism via multivalent bonds. We empirically fitted these distributions using a time-dependent unbinding rate parameter, koff, which diverges from standard treatment of koff as a constant. We further explain how to convert these models to fit ensemble-averaged binding data

Step-to-step variability in treadmill walking: influence of rhythmic auditory cueing.

Directory of Open Access Journals (Sweden)

Philippe Terrier

Full Text Available While walking, human beings continuously adjust step length (SpL, step time (SpT, step speed (SpS = SpL/SpT and step width (SpW by integrating both feedforward and feedback mechanisms. These motor control processes result in correlations of gait parameters between consecutive strides (statistical persistence. Constraining gait with a speed cue (treadmill and/or a rhythmic auditory cue (metronome, modifies the statistical persistence to anti-persistence. The objective was to analyze whether the combined effect of treadmill and rhythmic auditory cueing (RAC modified not only statistical persistence, but also fluctuation magnitude (standard deviation, SD, and stationarity of SpL, SpT, SpS and SpW. Twenty healthy subjects performed 6 × 5 min. walking tests at various imposed speeds on a treadmill instrumented with foot-pressure sensors. Freely-chosen walking cadences were assessed during the first three trials, and then imposed accordingly in the last trials with a metronome. Fluctuation magnitude (SD of SpT, SpL, SpS and SpW was assessed, as well as NonStationarity Index (NSI, which estimates the dispersion of local means in the times series (SD of 20 local means over 10 steps. No effect of RAC on fluctuation magnitude (SD was observed. SpW was not modified by RAC, what is likely the evidence that lateral foot placement is separately regulated. Stationarity (NSI was modified by RAC in the same manner as persistent pattern: Treadmill induced low NSI in the time series of SpS, and high NSI in SpT and SpL. On the contrary, SpT, SpL and SpS exhibited low NSI under RAC condition. We used relatively short sample of consecutive strides (100 as compared to the usual number of strides required to analyze fluctuation dynamics (200 to 1000 strides. Therefore, the responsiveness of stationarity measure (NSI to cued walking opens the perspective to perform short walking tests that would be adapted to patients with a reduced gait perimeter.

Significant decrease in congenital malformations in newborn infants of an unselected population of diabetic women

DEFF Research Database (Denmark)

Damm, P; Mølsted-Pedersen, L

1989-01-01

In an unselected and consecutive series of 1858 newborn infants of diabetic mothers, born in the Rigshospital, Copenhagen, in the period 1967 to 1986, congenital malformations were studied. The malformation rate in White Classes B to F was remarkably constant from 1967 to 1981, but a significant...... decrease in major congenital malformations was found in the period 1982 to 1986 versus 1977 to 1981 (2.7% vs. 7.4%, p less than 0.05). This decrease was mainly due to a fourfold decline in major congenital malformations in White Classes D and F (p less than 0.01), and consequently a correlation between...... the severity of maternal diabetes and the frequency of congenital malformations was no longer present. In the offspring of a control group of 1715 nondiabetic women, major congenital malformations were found in 1.7% (p greater than 0.05). Seventy-five percent of the diabetic pregnancies were planned...

Environmental Assessment Supplement for C-17Southwest Landing Zone Articulated Concrete Block Shoulders Travis Air Force Base, Fairfield, California

Science.gov (United States)

2012-03-01

considered in this opinion: or ( 4) a ncv . spt:cies is listed or criticCJI habitat designated that may be affected by the action. I r ym1 have...these <>ddresses in ycur web browse.- *"’ -track gH~’ ~ ~!g~u~~:*"’( ~e ’f~~ * f~:~~~~s;’ :~U~9Sh i~.!:~* 5 ~5"’~i"* I 0 il) SHIPME>NT QUESTIONS

Symmetry protected topological charge in symmetry broken phase: Spin-Chern, spin-valley-Chern and mirror-Chern numbers

International Nuclear Information System (INIS)

Ezawa, Motohiko

2014-01-01

The Chern number is a genuine topological number. On the other hand, a symmetry protected topological (SPT) charge is a topological number only when a symmetry exists. We propose a formula for the SPT charge as a derivative of the Chern number in terms of the Green function in such a way that it is valid and related to the associated Hall current even when the symmetry is broken. We estimate the amount of deviation from the quantized value as a function of the strength of the broken symmetry. We present two examples. First, we consider Dirac electrons with the spin–orbit coupling on honeycomb lattice, where the SPT charges are given by the spin-Chern, valley-Chern and spin-valley-Chern numbers. Though the spin-Chern charge is not quantized in the presence of the Rashba coupling, the deviation is estimated to be 10 −7 in the case of silicene, a silicon cousin of graphene. Second, we analyze the effect of the mirror-symmetry breaking of the mirror-Chern number in a thin-film of topological crystalline insulator.

Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling.

Science.gov (United States)

Scarlatti, Francesca; Sala, Giusy; Somenzi, Giulia; Signorelli, Paola; Sacchi, Nicoletta; Ghidoni, Riccardo

2003-12-01

Resveratrol (3,4',5-trans-trihydroxystilbene), a phytoalexin present in grapes and red wine, is emerging as a natural compound with potential anticancer properties. Here we show that resveratrol can induce growth inhibition and apoptosis in MDA-MB-231, a highly invasive and metastatic breast cancer cell line, in concomitance with a dramatic endogenous increase of growth inhibitory/proapoptotic ceramide. We found that accumulation of ceramide derives from both de novo ceramide synthesis and sphingomyelin hydrolysis. More specifically we demonstrated that ceramide accumulation induced by resveratrol can be traced to the activation of serine palmitoyltransferase (SPT), the key enzyme of de novo ceramide biosynthetic pathway, and neutral sphingomyelinase (nSMase), a main enzyme involved in the sphingomyelin/ceramide pathway. However, by using specific inhibitors of SPT, myriocin and L-cycloserine, and nSMase, gluthatione and manumycin, we found that only the SPT inhibitors could counteract the biological effects induced by resveratrol. Thus, resveratrol seems to exert its growth inhibitory/apoptotic effect on the metastatic breast cancer cell line MDA-MB-231 by activating the de novo ceramide synthesis pathway.

Performance of a shallow-focus applied-magnetic-field diode for ion-beam-transport experiments

Energy Technology Data Exchange (ETDEWEB)

Young, F.C.; Neri, J.M.; Ottinger, P.F. [Naval Research Lab., Washington, DC (United States); Rose, D.V. [JAYCOR, Vienna (Vatican City State, Holy See); Jones, T.G.; Oliver, B.V.

1997-12-31

An applied-magnetic-field ion diode to study the transport of intense ion beams for light-ion inertial confinement fusion is being operated on the Gamble II generator at NRL. A Large-area (145-cm{sup 2}), shallow-focusing diode is used to provide the ion beam required for self-pinched transport (SPT) experiments. Experiments have demonstrated focusing at 70 cm for 1.2-MV, 40-kA protons. Beyond the focus, the beam hollows out consistent with 20--30 mrad microdivergence. The effect of the counter-pulse B-field on altering the ion-beam trajectories and improving the focus has been diagnosed with a multiple-pinhole-camera using radiachromic film. This diagnostic is also used to determine the radial and azimuthal uniformity of ion emission at the anode for different B-field conditions. Increasing the diode voltage to 1.5 MV and optimizing the ion current are planned before initiating SPT experiments. Experiments to measure the spatial beam profile at focus, i.e., the SPT channel entrance, are in progress. Results are presented.

Policy and governance for sustainable consumption at the crossroads of theories and concepts

DEFF Research Database (Denmark)

Keller, Margit; Halkier, Bente; Wilska, Terhi-Anna

2016-01-01

This introductory article of the special issue compares different conceptual underpinnings of efforts to make the everyday activities of consumers more sustainable. As social practice theory (SPT) is the main theoretical foundation of the articles collected here, we outline its strengths and limi......This introductory article of the special issue compares different conceptual underpinnings of efforts to make the everyday activities of consumers more sustainable. As social practice theory (SPT) is the main theoretical foundation of the articles collected here, we outline its strengths...... and limitations, when compared with the dominant individual-oriented behaviour change approach, and we focus on theories of planned behaviour, social marketing as well as ‘choice architecture’, based on behavioural economics. This article analyses SPT's usefulness, particularly from the applied point of view...... to the need for more focus on consumers' workplace practices alongside domestic practices and analysis of and intervention in the material environments and objects in which social practices are embedded. Finally, they are concerned with the identification of moments of transition in consumers' lives...

Evaluation of Food Allergy in Children by Skin Prick Tests with Commercial Extracts and Fresh Foods, Specific IgE and, Open Oral Food Challenge-Our Five Years Experience in Food Allergy Work-up.

Science.gov (United States)

Zivanovic, Mirjana; Atanasković-Marković, Marina; Medjo, Biljana; Gavrović-Jankulović, Marija; Smiljanić, Katarina; Tmušić, Vladimir; Djurić, Vojislav

2017-04-01

IgE- mediated food allergy affects 6-8% of children. Our study aimed to define the correlations between the results obtained with skin prick tests (SPTs) using commercial extracts and fresh foods, and the correlations between these result and those obtained with specific IgE (sIgE) and/ or challenge. Children aged from 2 months to 6 years were recruited prospectively. Overall 571 children were positive to one food. In all children we performed  SPT using commercial extracts of suspected food and fresh foods and sIgE. If SPT and sIgE test results did not correspond to the history, we performed open oral food challenge. Sensitivity of SPT with commercial extracts for all tested food was poor (3-35%), while  sensitivity of fresh food skin prick tests (FFSPT) was excellent (50-100%), and showed correlation with open oral food challenge (pfood extracts are more effective in detecting sensitization and with levels of sIgE greater than class 3 could predict clinical reactivity, without the need for potentially hazardous food challenges.

Dynamic Site Characterization and Correlation of Shear Wave Velocity with Standard Penetration Test ` N' Values for the City of Agartala, Tripura State, India

Science.gov (United States)

Sil, Arjun; Sitharam, T. G.

2014-08-01

Seismic site characterization is the basic requirement for seismic microzonation and site response studies of an area. Site characterization helps to gauge the average dynamic properties of soil deposits and thus helps to evaluate the surface level response. This paper presents a seismic site characterization of Agartala city, the capital of Tripura state, in the northeast of India. Seismically, Agartala city is situated in the Bengal Basin zone which is classified as a highly active seismic zone, assigned by Indian seismic code BIS-1893, Indian Standard Criteria for Earthquake Resistant Design of Structures, Part-1 General Provisions and Buildings. According to the Bureau of Indian Standards, New Delhi (2002), it is the highest seismic level (zone-V) in the country. The city is very close to the Sylhet fault (Bangladesh) where two major earthquakes ( M w > 7) have occurred in the past and affected severely this city and the whole of northeast India. In order to perform site response evaluation, a series of geophysical tests at 27 locations were conducted using the multichannel analysis of surface waves (MASW) technique, which is an advanced method for obtaining shear wave velocity ( V s) profiles from in situ measurements. Similarly, standard penetration test (SPT-N) bore log data sets have been obtained from the Urban Development Department, Govt. of Tripura. In the collected data sets, out of 50 bore logs, 27 were selected which are close to the MASW test locations and used for further study. Both the data sets ( V s profiles with depth and SPT-N bore log profiles) have been used to calculate the average shear wave velocity ( V s30) and average SPT-N values for the upper 30 m depth of the subsurface soil profiles. These were used for site classification of the study area recommended by the National Earthquake Hazard Reduction Program (NEHRP) manual. The average V s30 and SPT-N classified the study area as seismic site class D and E categories, indicating that

Phase structure and electrochemical properties of La0.67Mg0.33Ni3.0-xCox (x=0.0, 0.25, 0.5, 0.75) hydrogen storage alloys

International Nuclear Information System (INIS)

Wang Dahui; Luo Yongchun; Yan Ruxu; Zhang Faliang; Kang Long

2006-01-01

La 0.67 Mg 0.33 Ni 3.0-x Co x (x=0.0, 0.25, 0.50, 0.75) hydrogen storage alloys were prepared by induction melting. Influences of partial substitution of Co for Ni on phase structure and electrochemical properties of La 0.67 Mg 0.33 Ni 3.0 were investigated by means of X-ray diffraction (XRD), electron probe X-ray microanalysis (EPMA) and electrochemical measurements. XRD patterns and back scattered electron images show that the alloys were composed of the (La,Mg)Ni 3 phase with the PuNi 3 -type structure and the (La,Mg) 2 Ni 7 phase with the Ce 2 Ni 7 -type structure. The lattice parameters a, c and the unit-cell volumes v vary with the increase of Co content x. The electrochemical measurements show that partial Co substitution for Ni had no influence on the initial activation rate of the alloys. The maximum electrochemical discharge capacity increases firstly then decreases, the high-rate dischargeabilities (HRDs) of La 0.67 Mg 0.33 Ni 3.0-x Co x alloy electrodes increase with the increase of Co content. Moreover, the cycle stabilities of La 0.67 Mg 0.33 Ni 3.0-x Co x is not improved by small quantity replacement Ni by Co except for x=0.75

Precision dosimetry system suited for low temperature radiation damage experiments

DEFF Research Database (Denmark)

Andersen, H.H.; Hanke, C.C.; Sørensen, H.

1967-01-01

A calorimetric system for dosimetry on a beam of charged particles is described. The calorimeter works at liquid helium temperature. The total dose may be measured with an accuracy of 0.3%, and the dose per area with 0.4%. No theoretical corrections are needed. © 1967 The American Institute...

Detection of some safe plant-derived foods for LTP-allergic patients.

Science.gov (United States)

Asero, Riccardo; Mistrello, Gianni; Roncarolo, Daniela; Amato, Stefano

2007-01-01

Lipid transfer protein (LTP) is a widely cross-reacting plant pan-allergen. Adverse reactions to Rosaceae, tree nuts, peanut, beer, maize, mustard, asparagus, grapes, mulberry, cabbage, dates, orange, fig, kiwi, lupine, fennel, celery, tomato, eggplant, lettuce, chestnut and pineapple have been recorded. To detect vegetable foods to be regarded as safe for LTP-allergic patients. Tolerance/intolerance to a large spectrum of vegetable foods other than Rosaceae, tree nuts and peanut was assessed by interview in 49 subjects monosensitized to LTP and in three distinct groups of controls monosensitized to Bet v 1 (n = 24) or Bet v 2 (n = 18), or sensitized to both LTP and birch pollen (n = 16), all with a history of vegetable food allergy. Patients and controls underwent skin prick test (SPT) with a large spectrum of vegetable foods. The absence of IgE reactivity to foods that were negative in both clinical history and SPT was confirmed by immunoblot analysis and their clinical tolerance was finally assessed by open oral challenge (50 g per food). All patients reported tolerance and showed negative SPT to carrot, potato, banana and melon; these foods scored positive in SPT and elicited clinical symptoms in a significant proportion of patients from all three control groups. All patients tolerated these four foods on oral challenge. Immunoblot analysis confirmed the lack of IgE reactivity to these foods by LTP-allergic patients. Carrot, potato, banana and melon seem safe for LTP-allergic patients. This finding may be helpful for a better management of allergy to LTP.

Efeitos do estádio de desenvolvimento da antera e da radiação gama na formação de calos derivados de anteras de tomate Anther development stage and gamma radiation effects on tomato anther-derived callus formation

Directory of Open Access Journals (Sweden)

Ana Christina R. Brasileiro

1999-10-01

Full Text Available Este trabalho foi conduzido visando: (I determinar a influência do estádio de desenvolvimento de anteras de tomate sobre a formação de calos e (II analisar o efeito da radiação gama no cultivo in vitro de anteras. No primeiro experimento, anteras de híbridos de tomate IPA 5 x Rotam 4 (F1 foram cultivadas em três meios nutritivos. Apesar da formação de calos ter sido induzida em todos os estádios de desenvolvimento, variando de prófase I à micrósporo mononucleado, a freqüência de calos produzidos decresceu com o avanço do estádio de desenvolvimento e se apresentou de forma semelhante nos meios testados. Anteras contendo meiócitos em estádio de prófase I mostraram maior freqüência de formação de calos. Tanto o comprimento da antera quanto o do botão floral apresentaram correlação significativa com o estádio de desenvolvimento. No segundo experimento, sementes e botões florais dos híbridos IPA 5 x Rotam 4 (F2, IPA 6 x Rotam 4 (F2 e IPA 8 x 217.1 (F2 foram submetidos à radiação gama e suas anteras foram cultivadas em dois meios descritos por Gresshoff & Doy (1972, contendo 2,0 mg L-1 de ANA + 5,0 mg L-1 de cinetina e 2,0 mg L-1 de ANA + 1,0 mg L-1 de cinetina. Não foram constatadas diferenças significativas, no que se refere à formação de calos, para os genótipos e doses estudadas - 200 Gy, para sementes e 20 Gy, para botões florais.Two experiments were carried (I to determine tomato anther development stage influence on callus production; and (II to investigate gamma radiation effects on anther culture. In the first experiment, anthers of a tomato hybrid (IPA 5 x Rotam 4 - F1 were grown on three media. Although calli were induced at all stages of anther development, varying from prophase I to mononucleate microspore, callus frequency decreased as anther development progressed and calli induction were not significantly affected by all media tested. Anthers containing prophase I meiocytes produced the highest

A randomized controlled study of peanut oral immunotherapy (OIT): clinical desensitization and modulation of the allergic response

Science.gov (United States)

Varshney, Pooja; Jones, Stacie M.; Scurlock, Amy M.; Perry, Tamara T.; Kemper, Alex; Steele, Pamela; Hiegel, Anne; Kamilaris, Janet; Carlisle, Suzanne; Yue, Xiaohong; Kulis, Mike; Pons, Laurent; Vickery, Brian; Burks, A. Wesley

2011-01-01

Background Open-label oral immunotherapy (OIT) protocols have been used to treat small numbers of patients with peanut allergy. Peanut OIT has not been evaluated in double-blind, placebo-controlled trials. Objective To investigate the safety and effectiveness of OIT for peanut allergy in a double blind, placebo-controlled study. Methods In this multicenter study, peanut-allergic children ages 1-16 years received OIT with peanut flour or placebo. Initial escalation, build-up, and maintenance phases were followed by an oral food challenge at approximately one year. Titrated skin prick tests (SPT) and laboratory studies were performed at regular intervals. Results Twenty-eight subjects were enrolled in the study. Three peanut OIT subjects withdrew early in the study due to allergic side effects. During the double-blind, placebo-controlled food challenge, all remaining peanut OIT subjects (N=16) ingested the maximum cumulative dose of 5000 mg (approximately 20 peanuts), while placebo subjects (N=9) ingested a median cumulative dose of 280 mg (range, 0-1900 mg) [p<0.001]. In contrast to the placebo group, the peanut OIT group showed reductions in SPT size (p<0.001), IL-5 (p=0.01), and IL-13 (p=0.02) and increases in peanut-specific IgG4 (p<0.001). Peanut OIT subjects had initial increases in peanut-specific IgE (p<0.01) but did not show significant change from baseline by the time of OFC. The ratio of FoxP3 hi: FoxP3 intermediate CD4+CD25+ T cells increased at the time of OFC (p=0.04) in peanut OIT subjects. Conclusion These results conclusively demonstrate that peanut OIT induces desensitization and concurrent immune modulation. The present study continues and is evaluating the hypothesis that peanut OIT causes long-term immune tolerance. PMID:21377034

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